Antibody data
- Antibody Data
- Antigen structure
- References [12]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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Validation data
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- Product number
- 10527-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#10527-1-AP, RRID:AB_2154659
- Product name
- NRG1 antibody
- Antibody type
- Polyclonal
- Description
- NRG1 antibody (Cat. #10527-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: IF, IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Identification and validation of CRLF1 and NRG1 as immune-related signatures in hypertrophic scar.
Empagliflozin and liraglutide ameliorate HFpEF in mice via augmenting the Erbb4 signaling pathway.
Jatrorrhizine ameliorates Schwann cell myelination via inhibiting HDAC3 ability to recruit Atxn2l for regulating the NRG1-ErbB2-PI3K-AKT pathway in diabetic peripheral neuropathy mice.
Spatiotemporal transcriptome atlas reveals the regional specification of the developing human brain.
Interferon-dependent SLC14A1(+) cancer-associated fibroblasts promote cancer stemness via WNT5A in bladder cancer.
Prenatal di-(2-ethylhexyl) phthalate exposure induced myocardial cytotoxicity via the regulation of the NRG1-dependent ErbB2/ErbB4-PI3K/AKT signaling pathway in fetal mice.
Extracellular Vesicle-Encapsulated miR-183-5p from Rhynchophylline-Treated H9c2 Cells Protect against Methamphetamine-Induced Dependence in Mouse Brain by Targeting NRG1.
miR-143-3p inhibition promotes neuronal survival in an Alzheimer's disease cell model by targeting neuregulin-1.
Therapeutic effects of Erbin inhibitor on spinal cord contusion in mice.
Sericin Nerve Guidance Conduit Delivering Therapeutically Repurposed Clobetasol for Functional and Structural Regeneration of Transected Peripheral Nerves.
miR-296-5p suppresses EMT of hepatocellular carcinoma via attenuating NRG1/ERBB2/ERBB3 signaling.
ErbB4 deletion accelerates renal fibrosis following renal injury.
Yu B, Cao Y, Li S, Bai R, Zhou G, Fu Q, Liang L, Gu W, Zhang L, Chen M
Genomics 2024 Mar;116(2):110797
Genomics 2024 Mar;116(2):110797
Empagliflozin and liraglutide ameliorate HFpEF in mice via augmenting the Erbb4 signaling pathway.
Ni XY, Feng XJ, Wang ZH, Zhang Y, Little PJ, Cao Y, Xu SW, Tang LQ, Weng JP
Acta pharmacologica Sinica 2024 Aug;45(8):1604-1617
Acta pharmacologica Sinica 2024 Aug;45(8):1604-1617
Jatrorrhizine ameliorates Schwann cell myelination via inhibiting HDAC3 ability to recruit Atxn2l for regulating the NRG1-ErbB2-PI3K-AKT pathway in diabetic peripheral neuropathy mice.
Gong X, Gui Z, Ye X, Li X
Phytotherapy research : PTR 2023 Feb;37(2):645-657
Phytotherapy research : PTR 2023 Feb;37(2):645-657
Spatiotemporal transcriptome atlas reveals the regional specification of the developing human brain.
Li Y, Li Z, Wang C, Yang M, He Z, Wang F, Zhang Y, Li R, Gong Y, Wang B, Fan B, Wang C, Chen L, Li H, Shi P, Wang N, Wei Z, Wang YL, Jin L, Du P, Dong J, Jiao J
Cell 2023 Dec 21;186(26):5892-5909.e22
Cell 2023 Dec 21;186(26):5892-5909.e22
Interferon-dependent SLC14A1(+) cancer-associated fibroblasts promote cancer stemness via WNT5A in bladder cancer.
Ma Z, Li X, Mao Y, Wei C, Huang Z, Li G, Yin J, Liang X, Liu Z
Cancer cell 2022 Dec 12;40(12):1550-1565.e7
Cancer cell 2022 Dec 12;40(12):1550-1565.e7
Prenatal di-(2-ethylhexyl) phthalate exposure induced myocardial cytotoxicity via the regulation of the NRG1-dependent ErbB2/ErbB4-PI3K/AKT signaling pathway in fetal mice.
Yu D, Zhu D, Wang X, Li B, Li J, Lu P, Ji Y, Wang X
Ecotoxicology and environmental safety 2022 Aug;241:113771
Ecotoxicology and environmental safety 2022 Aug;241:113771
Extracellular Vesicle-Encapsulated miR-183-5p from Rhynchophylline-Treated H9c2 Cells Protect against Methamphetamine-Induced Dependence in Mouse Brain by Targeting NRG1.
Zhou Y, Xiao S, Li C, Chen Z, Zhu C, Zhou Q, Ou J, Li J, Chen Y, Luo C, Mo Z
Evidence-based complementary and alternative medicine : eCAM 2021;2021:2136076
Evidence-based complementary and alternative medicine : eCAM 2021;2021:2136076
miR-143-3p inhibition promotes neuronal survival in an Alzheimer's disease cell model by targeting neuregulin-1.
Sun C, Jia N, Li R, Zhang Z, Zhong Y, Han K
Folia neuropathologica 2020;58(1):10-21
Folia neuropathologica 2020;58(1):10-21
Therapeutic effects of Erbin inhibitor on spinal cord contusion in mice.
Wu Y, Chen H, Tan Z, Li D, Liang C
American journal of translational research 2019;11(4):2570-2579
American journal of translational research 2019;11(4):2570-2579
Sericin Nerve Guidance Conduit Delivering Therapeutically Repurposed Clobetasol for Functional and Structural Regeneration of Transected Peripheral Nerves.
Zhang L, Yang W, Xie H, Wang H, Wang J, Su Q, Li X, Song Y, Wang G, Wang L, Wang Z
ACS biomaterials science & engineering 2019 Mar 11;5(3):1426-1439
ACS biomaterials science & engineering 2019 Mar 11;5(3):1426-1439
miR-296-5p suppresses EMT of hepatocellular carcinoma via attenuating NRG1/ERBB2/ERBB3 signaling.
Shi DM, Li LX, Bian XY, Shi XJ, Lu LL, Zhou HX, Pan TJ, Zhou J, Fan J, Wu WZ
Journal of experimental & clinical cancer research : CR 2018 Nov 29;37(1):294
Journal of experimental & clinical cancer research : CR 2018 Nov 29;37(1):294
ErbB4 deletion accelerates renal fibrosis following renal injury.
Zeng F, Miyazawa T, Kloepfer LA, Harris RC
American journal of physiology. Renal physiology 2018 May 1;314(5):F773-F787
American journal of physiology. Renal physiology 2018 May 1;314(5):F773-F787
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- human liver tissue were subjected to SDS PAGE followed by western blot with 10527-1-AP(NRG1 antibody) at dilution of 1:250
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The NRG1 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human NRG1. This antibody recognizes human, mouse antigen. The NRG1 antibody has been validated for the following applications: ELISA, WB, IHC analysis.