BS6037

antibody from Bioworld Technology, Inc
Targeting: NRG1 GGF, HGL, HRG, NDF, NRG1-IT2
Provider product page for BS6037
Western blot
Immunohistochemistry

Antibody data

Product number
BS6037 - Provider product page
Provider
Bioworld Technology, Inc
Product name
NRG1 polyclonal antibody
Antibody type
Polyclonal
Antigen
Recombinant full length Human NRG1.
Description
Neuregulin-1 gene, NRG1, encodes numerous splice variants with differing transcription initiation sites. Neuregulin-1 includes a range of isoforms with varying glycosylation, regulation of expression and function. Neuregulin-1 splice variants each bear an EGF-like domain, though otherwise have unique domain structures, differing functions and discrete tissue distribution. Six types of Neuregulin-1 isoform groups have been defined based on their structural features. Three types are most often described, type I (ARIA, NDF or HRG), type II (GGF) and type III (SMDF). Neuregulin-1 has been linked to schizophrenia and has diverse neural functions. Neuregulin-1 affects cell migration, the differentiation of neural crest and Schwann cells, and acts to upregulate the expression of acetylcholine receptors at muscle fibers during the formation of neuromuscular junctions.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
NRG1 protein structure - BS6037 shown in red.