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Western blotAntibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
- Flow cytometry [1]
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- Product number
- PAB4805 - Provider product page
- Provider
- Abnova Corporation
- Proper citation
- Abnova Corporation Cat#PAB4805, RRID:AB_1578191
- Product name
- NRG1 polyclonal antibody
- Antibody type
- Polyclonal
- Description
- Rabbit polyclonal antibody raised against synthetic peptide of NRG1.
- Storage
- Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.
Submitted references The heregulin/human epidermal growth factor receptor as a new growth factor system in melanoma with multiple ways of deregulation.
Neuregulin-1 enhances motility and migration of human astrocytic glioma cells.
A recurrent chromosome translocation breakpoint in breast and pancreatic cancer cell lines targets the neuregulin/NRG1 gene.
Stove C, Stove V, Derycke L, Van Marck V, Mareel M, Bracke M
The Journal of investigative dermatology 2003 Oct;121(4):802-12
The Journal of investigative dermatology 2003 Oct;121(4):802-12
Neuregulin-1 enhances motility and migration of human astrocytic glioma cells.
Ritch PA, Carroll SL, Sontheimer H
The Journal of biological chemistry 2003 Jun 6;278(23):20971-8
The Journal of biological chemistry 2003 Jun 6;278(23):20971-8
A recurrent chromosome translocation breakpoint in breast and pancreatic cancer cell lines targets the neuregulin/NRG1 gene.
Adélaïde J, Huang HE, Murati A, Alsop AE, Orsetti B, Mozziconacci MJ, Popovici C, Ginestier C, Letessier A, Basset C, Courtay-Cahen C, Jacquemier J, Theillet C, Birnbaum D, Edwards PA, Chaffanet M
Genes, chromosomes & cancer 2003 Aug;37(4):333-45
Genes, chromosomes & cancer 2003 Aug;37(4):333-45
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Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Western blot analysis of NRG1 polyclonal antibody (Cat # PAB4805) in SK-BR-3 cell lysate (35 ug/lane). NRG1 (arrow) was detected using the purified polyclonal antibody.
Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Formalin-fixed and paraffin-embedded human cancer tissue reacted with NRG1 polyclonal antibody (Cat # PAB4805) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry ; clinical relevance has not been evaluated. BC = breast carcinoma.
- Validation comment
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Flow cytometric analysis of NCI-H460 cells using NRG1 polyclonal antibody (Cat # PAB4805) (bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
- Validation comment
- Flow Cytometry
