FNab01444

antibody from FineTest Biotech

Targeting: CD22 SIGLEC-2, SIGLEC2

Western blot

ELISA

Immunohistochemistry

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Validation data

Product number: FNab01444 - Provider product page
Provider: FineTest Biotech
Product name: CD22 antibody
Antibody type: Monoclonal
Antigen: Recombinant protein fragment
Description: Mediates B-cell B-cell interactions. May be involved in the localization of B-cells in lymphoid tissues. Binds sialylated glycoproteins; one of which is CD45. Preferentially binds to alpha-2,6-linked sialic acid. The sialic acid recognition site can be masked by cis interactions with sialic acids on the same cell surface. Upon ligand induced tyrosine phosphorylation in the immune response seems to be involved in regulation of B-cell antigen receptor signaling. Plays a role in positive regulation through interaction with Src family tyrosine kinases and may also act as an inhibitory receptor by recruiting cytoplasmic phosphatases via their SH2 domains that block signal transduction through dephosphorylation of signaling molecules.
Reactivity: Human
Host: Mouse
Conjugate: Unconjugated
Antigen sequence: CD22 molecule
Epitope: IgG1
Isotype: IgG
Antibody clone number: 7D10
Vial size: 100¦Ìg
Concentration: Protein A+G purification
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)
Handling: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)

CD22 protein structure - FNab01444 shown in red.