Antibody data
- Antibody Data
- Antigen structure
- References [0]
- Comments [0]
- Validations
- Flow cytometry [1]
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Validation data
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- Product number
- 302839 - Provider product page
- Provider
- BioLegend
- Proper citation
- BioLegend Cat#302839, RRID:AB_2562817
- Product name
- Purified anti-human CD27 (MaxPar® Ready)
- Antibody type
- Monoclonal
- Antigen
- 0
- Description
- CD27 is a 50-55 kD type I membrane protein also known as S152 and T14. It is a lymphocyte-specific member of the TNF-receptor superfamily. CD27 is expressed on medullary thymocytes, virtually all mature T cells, some B cells, and NK cells. CD27 binds to CD70 and plays an important role in costimulation of T cell activation, and regulation of B cell differentiation and proliferation. The cytoplasmic domains of CD27 have also been shown to interact with TRAF2 and TRAF5 to elicit NF-κB and SAPK/JNK activation.
- Reactivity
- Human
- Host
- Mouse
- Conjugate
- Unconjugated
- Antibody clone number
- O323
- Vial size
- 100 µg
- Concentration
- 1 mg/ml
- Storage
- 2°C-8°C
- Handling
- Ambient RT
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Supportive validation
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- BioLegend (provider)
- Main image
- Experimental details
- Human PBMCs stained with 154Sm-anti-CD45 (HI30) and 167Er-anti-CD27 (O323).
- Conjugate
- Unconjugated