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Western blot
Flow cytometryAntibody data
- Antibody Data
- Antigen structure
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- Validations
- Flow cytometry [1]
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- Product number
- 348502 - Provider product page
- Provider
- BioLegend
- Proper citation
- BioLegend Cat#348502, RRID:AB_10588267
- Product name
- Purified anti-human CD144 (VE-Cadherin)
- Antibody type
- Monoclonal
- Antigen
- CD144
- Description
- CD144, also known as VE-cadherin and cadherin-5, is a 140 kD glycoprotein which is composed of 5 extracellular cadherin repeats and a highly conserved cytoplasmic tail region. It is a calcium-dependent transmembrane cell-cell adhesion molecule localized at the intercellular boundaries of endothelial cells, hematopoietic stem cells, and <a href=\http://www.copewithcytokines.de/cope.cgi?key=perineurial%20cells">perineurial cells</a>. It functions as a classic cadherin by mediating homophilic adhesion and functions as a plasma membrane attachment site for the cytoskeleton. CD144 is thought to play a role in vascular development, permeability, and remodeling.
- Reactivity
- Human
- Host
- Mouse
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 100 µg
- Concentration
- 0.5 mg/ml
- Storage
- The antibody solution should be stored undiluted at 4°C.
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Supportive validation
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- BioLegend (provider)
- Main image
- Experimental details
- Human umbilial vein endothelial cells, HUVEC, stained with purified BV9 conjugated with PE
- Conjugate
- Unconjugated
