Antibody data
- Antibody Data
- Antigen structure
- References [8]
- Comments [0]
- Validations
- Western blot [2]
- ELISA [1]
- Immunohistochemistry [2]
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Validation data
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- Product number
- AF972 - Provider product page
- Provider
- Novus Biologicals
- Product name
- Goat Polyclonal EMMPRIN/CD147 Antibody
- Antibody type
- Polyclonal
- Description
- Antigen Affinity-purified. Detects human EMMPRIN/CD147 in direct ELISAs and Western blots. In direct ELISAs and Western blots, less than 5% cross-reactivity with recombinant mouse EMMPRIN is observed.
- Reactivity
- Human
- Host
- Goat
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 100 ug
- Concentration
- LYOPH
- Storage
- Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 degreesC as supplied. 1 month, 2 to 8 degreesC under sterile conditions after reconstitution. 6 months, -20 to -70 degreesC under sterile conditions after reconstitution.
Submitted references CD73 complexes with emmprin to regulate MMP-2 production from co-cultured sarcoma cells and fibroblasts.
Structure of the human plasma membrane Ca2+-ATPase 1 in complex with its obligatory subunit neuroplastin.
Efficacy Evaluation of Combination Treatment Using Gemcitabine and Radioimmunotherapy with (90)Y-Labeled Fully Human Anti-CD147 Monoclonal Antibody 059-053 in a BxPC-3 Xenograft Mouse Model of Refractory Pancreatic Cancer.
Cryopreserved Mesenchymal Stromal Cells Maintain Potency in a Retinal Ischemia/Reperfusion Injury Model: Toward an off-the-shelf Therapy.
Resveratrol blocks interleukin-18-EMMPRIN cross-regulation and smooth muscle cell migration.
Emmprin in epithelioid sarcoma: expression in tumor cell membrane and stimulation of MMP-2 production in tumor-associated fibroblasts.
Expression of emmprin and matrix metalloproteinases (MMPs) in peripheral nerve sheath tumors: emmprin and membrane-type (MT)1-MMP expressions are associated with malignant potential.
CD147 facilitates HIV-1 infection by interacting with virus-associated cyclophilin A.
Aoki M, Koga K, Miyazaki M, Hamasaki M, Koshikawa N, Oyama M, Kozuka-Hata H, Seiki M, Toole BP, Nabeshima K
BMC cancer 2019 Sep 12;19(1):912
BMC cancer 2019 Sep 12;19(1):912
Structure of the human plasma membrane Ca2+-ATPase 1 in complex with its obligatory subunit neuroplastin.
Gong D, Chi X, Ren K, Huang G, Zhou G, Yan N, Lei J, Zhou Q
Nature communications 2018 Sep 6;9(1):3623
Nature communications 2018 Sep 6;9(1):3623
Efficacy Evaluation of Combination Treatment Using Gemcitabine and Radioimmunotherapy with (90)Y-Labeled Fully Human Anti-CD147 Monoclonal Antibody 059-053 in a BxPC-3 Xenograft Mouse Model of Refractory Pancreatic Cancer.
Sugyo A, Tsuji AB, Sudo H, Koizumi M, Ukai Y, Kurosawa G, Kurosawa Y, Saga T, Higashi T
International journal of molecular sciences 2018 Sep 29;19(10)
International journal of molecular sciences 2018 Sep 29;19(10)
Cryopreserved Mesenchymal Stromal Cells Maintain Potency in a Retinal Ischemia/Reperfusion Injury Model: Toward an off-the-shelf Therapy.
Gramlich OW, Burand AJ, Brown AJ, Deutsch RJ, Kuehn MH, Ankrum JA
Scientific reports 2016 May 23;6:26463
Scientific reports 2016 May 23;6:26463
Resveratrol blocks interleukin-18-EMMPRIN cross-regulation and smooth muscle cell migration.
Venkatesan B, Valente AJ, Reddy VS, Siwik DA, Chandrasekar B
American journal of physiology. Heart and circulatory physiology 2009 Aug;297(2):H874-86
American journal of physiology. Heart and circulatory physiology 2009 Aug;297(2):H874-86
Emmprin in epithelioid sarcoma: expression in tumor cell membrane and stimulation of MMP-2 production in tumor-associated fibroblasts.
Koga K, Nabeshima K, Aoki M, Kawakami T, Hamasaki M, Toole BP, Nakayama J, Iwasaki H
International journal of cancer 2007 Feb 15;120(4):761-8
International journal of cancer 2007 Feb 15;120(4):761-8
Expression of emmprin and matrix metalloproteinases (MMPs) in peripheral nerve sheath tumors: emmprin and membrane-type (MT)1-MMP expressions are associated with malignant potential.
Nabeshima K, Iwasaki H, Nishio J, Koga K, Shishime M, Kikuchi M
Anticancer research 2006 Mar-Apr;26(2B):1359-67
Anticancer research 2006 Mar-Apr;26(2B):1359-67
CD147 facilitates HIV-1 infection by interacting with virus-associated cyclophilin A.
Pushkarsky T, Zybarth G, Dubrovsky L, Yurchenko V, Tang H, Guo H, Toole B, Sherry B, Bukrinsky M
Proceedings of the National Academy of Sciences of the United States of America 2001 May 22;98(11):6360-5
Proceedings of the National Academy of Sciences of the United States of America 2001 May 22;98(11):6360-5
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Detection of Human EMMPRIN/CD147 by Simple WesternTM. Detection of Human EMMPRIN/CD147 by Simple WesternTM.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Detection of Human EMMPRIN/CD147 by Western Blot. Detection of Human EMMPRIN/CD147 by Western Blot.
Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Human EMMPRIN/CD147 ELISA Standard Curve.
Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- EMMPRIN/CD147 in Human Stomach Cancer Tissue. EMMPRIN/CD147 in Human Stomach Cancer Tissue.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- EMMPRIN/CD147 in Human Cervix. EMMPRIN/CD147 in Human Cervix.