BS4840

antibody from Bioworld Technology, Inc
Targeting: GATA1 ERYF1, GATA-1, GF1, NF-E1, NFE1
Provider product page for BS4840
Western blot
Immunoprecipitation
Immunohistochemistry

Antibody data

Product number
BS4840 - Provider product page
Provider
Bioworld Technology, Inc
Product name
GATA 1 (phospho S142) polyclonal antibody
Antibody type
Polyclonal
Antigen
Synthetic phosphopeptide derived from human GATA1 around the phosphorylation site of Serine 142.
Description
GATA1 (Globin transcription factor 1) is a Cys2/Cys2 zinc finger DNA binding protein that is expressed primarily in erythroid, megakaryocytic, mast cells and eosinophilic cells. It belongs to the GATA family of transcription factors. GATA1 is a transcriptional activator which probably serves as a general switch factor for erythroid development. It binds to DNA sites with the consensus sequence [AT]GATA[AG] within regulatory regions of globin genes and of other genes expressed in erythroid cells. The protein also plays an important role in erythroid development by regulating the switch of fetal hemoglobin to adult hemoglobin. Mutations in this gene have been associated with X-linked dyserythropoietic anemia and thrombocytopenia. Acquired somatic mutations in GATA1 occur in virtually all children with Down's Syndrome, congenital transient myeloproliferative syndrome (TMD) and acute megakaryocytic leukemia.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
GATA1 protein structure - BS4840 shown in red.