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Western blotAntibody data
- Antibody Data
- Antigen structure
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- Product number
- abx117135 - Provider product page
- Provider
- Abbexa
- Product name
- P-Selectin Glycoprotein Ligand 1 (SELPLG) Antibody
- Antibody type
- Polyclonal
- Description
- SELPLG Antibody is a Rabbit Polyclonal antibody against SELPLG. This gene encodes a glycoprotein that functions as a high affinity counter-receptor for the cell adhesion molecules P-, E- and L- selectin expressed on myeloid cells and stimulated T lymphocytesAs such, this protein plays a critical role in leukocyte trafficking during inflammation by tethering of leukocytes to activated platelets or endothelia expressing selectinsThis protein requires two post-translational modifications, tyrosine sulfation and the addition of the sialyl Lewis x tetrasaccharide (sLex) to its O-linked glycans, for its high-affinity binding activityAberrant expression of this gene and polymorphisms in this gene are associated with defects in the innate and adaptive immune responseAlternate splicing results in multiple transcript variants.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 100 µg
- Storage
- Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
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