abx117185

antibody from Abbexa

Targeting: SLAMF1 CD150, SLAM

Western blot (Recommended by provider)

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

abx117185

Provider

Abbexa

Product name

Signaling Lymphocytic Activation Molecule Family Member 1 / CD150 (SLAMF1) Antibody

Antibody type

Polyclonal

Description

SLAMF1 Antibody is a Rabbit Polyclonal antibody against SLAMF1. Following occupancy of the T cell receptor by antigen, T cell prolifeRation and lymphokine production are determined by a second costimulatory signal delivered by a ligand expressed on antigen-presenting cellsSLAM (for signaling lymphocyte-activation molecule, also designated CDw150) is a novel receptor on T cells that, when engaged, potentiates T cell expansion in a CD28-independent mannerSAP (for SLAM-associated protein) contains an SH2 domain and functions to inhibit SH-PTP2 recruitment to the SLAM docking site, an activity induced by Fyn phosphorylation of SLAMMutations of the SAP gene may be associated with X-linked lympho-prolifeRative disease (XLP).

Reactivity

Human

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Vial size

100 µg

Storage

Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.