PAB12822

antibody from Abnova Corporation

Targeting: TNFSF10 Apo-2L, CD253, TL2, TRAIL

Western blot (Supportive data in Antibodypedia)

Immunohistochemistry (Supportive data in Antibodypedia)

Antibody Data

Product number

PAB12822

Provider

Abnova Corporation

Proper citation

Abnova Corporation Cat#PAB12822, RRID:AB_10677243

Product name

TNFSF10 polyclonal antibody

Antibody type

Polyclonal

Description

Rabbit polyclonal antibody raised against synthetic peptide of TNFSF10.

Storage

Store at 4°C for three months. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.

References

Submitted references

TRAIL receptors 1 (DR4) and 2 (DR5) signal FADD-dependent apoptosis and activate NF-kappaB.

Schneider P, Thome M, Burns K, Bodmer JL, Hofmann K, Kataoka T, Holler N, Tschopp J
Immunity 1997 Dec;7(6):831-6

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The receptor for the cytotoxic ligand TRAIL.

Pan G, O'Rourke K, Chinnaiyan AM, Gentz R, Ebner R, Ni J, Dixit VM
Science (New York, N.Y.) 1997 Apr 4;276(5309):111-3

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Induction of apoptosis by Apo-2 ligand, a new member of the tumor necrosis factor cytokine family.

Pitti RM, Marsters SA, Ruppert S, Donahue CJ, Moore A, Ashkenazi A
The Journal of biological chemistry 1996 May 31;271(22):12687-90

Western blot

Supportive validation

Submitted by

Abnova Corporation (provider)

Main image

Experimental details

Western blot analysis of TRAIL in HeLa cell lysate containing 10, 2.5, or 1 ng of recombinant protein containing extracellular domain of TNSF10 with TNFSF10 polyclonal antibody (Cat # PAB12822) at 1 ug/mL.

Immunohistochemistry

Supportive validation

Submitted by

Abnova Corporation (provider)

Main image

Experimental details

Immunohistochemistry of TNFSF10 in human brain tissue with TNFSF10 polyclonal antibody (Cat # PAB12822) at 20 ug/mL .

Validation comment

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)