Antibody data
- Antibody Data
- Antigen structure
- References [6]
- Comments [0]
- Validations
- Western blot [1]
- Other assay [1]
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Validation data
Reference
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- Product number
- V2961 - Provider product page
- Provider
- NSJ Bioreagents
- Product name
- CD6 Antibody
- Antibody type
- Monoclonal
- Antigen
- A CD8+ cytotoxic T-cell clone was used as the immunogen for the CD6 antibody.
- Description
- Protein G purified antibody
- Reactivity
- Human
- Host
- Mouse
- Conjugate
- Unconjugated
- Antibody clone number
- SPV-L14
- Vial size
- 20 µg, 100 µg (with sodium azide), 100 µg (without sodium azide), 7 ml (prediluted for IHC use, if applicable)
- Storage
- Store the CD6 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
Submitted references Itolizumab - a humanized anti-CD6 monoclonal antibody with a better side effects profile for the treatment of psoriasis.
Pattern of soluble CD5 and CD6 lymphocyte receptors in critically ill patients with septic syndromes.
Mitogen-activated protein kinase pathway activation by the CD6 lymphocyte surface receptor.
The accessory molecules CD5 and CD6 associate on the membrane of lymphoid T cells.
Molecular analysis of the hematopoiesis supporting osteoblastic cell line U2-OS.
Cloning of a novel cell type from human fetal liver expressing cytoplasmic CD3 delta and epsilon but not membrane CD3.
Menon R, David BG
Clinical, cosmetic and investigational dermatology 2015;8:215-22
Clinical, cosmetic and investigational dermatology 2015;8:215-22
Pattern of soluble CD5 and CD6 lymphocyte receptors in critically ill patients with septic syndromes.
Aibar J, Martínez-Florensa M, Castro P, Carrasco E, Escoda-Ferran C, Fernández S, Butjosa M, Hernández C, Rinaudo M, Lozano F, Nicolás JM
Journal of critical care 2015 Oct;30(5):914-9
Journal of critical care 2015 Oct;30(5):914-9
Mitogen-activated protein kinase pathway activation by the CD6 lymphocyte surface receptor.
Ibáñez A, Sarrias MR, Farnós M, Gimferrer I, Serra-Pagès C, Vives J, Lozano F
Journal of immunology (Baltimore, Md. : 1950) 2006 Jul 15;177(2):1152-9
Journal of immunology (Baltimore, Md. : 1950) 2006 Jul 15;177(2):1152-9
The accessory molecules CD5 and CD6 associate on the membrane of lymphoid T cells.
Gimferrer I, Farnós M, Calvo M, Mittelbrunn M, Enrich C, Sánchez-Madrid F, Vives J, Lozano F
The Journal of biological chemistry 2003 Mar 7;278(10):8564-71
The Journal of biological chemistry 2003 Mar 7;278(10):8564-71
Molecular analysis of the hematopoiesis supporting osteoblastic cell line U2-OS.
Nelissen JM, Torensma R, Pluyter M, Adema GJ, Raymakers RA, van Kooyk Y, Figdor CG
Experimental hematology 2000 Apr;28(4):422-32
Experimental hematology 2000 Apr;28(4):422-32
Cloning of a novel cell type from human fetal liver expressing cytoplasmic CD3 delta and epsilon but not membrane CD3.
Hori T, de Waal Malefyt R, Duncan BW, Harrison MR, Roncarolo MG, Spits H
International immunology 1991 Apr;3(4):353-7
International immunology 1991 Apr;3(4):353-7
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Supportive validation
- Submitted by
- NSJ Bioreagents (provider)
- Main image
- Experimental details
- Western blot testing of Ramos cell lysate with CD6 antibody (clone SPV-L14). Expected molecular weight: 72/90~130kDa (unmodified/glycosylated).
Supportive validation
- Submitted by
- NSJ Bioreagents (provider)
- Main image
- Experimental details
- SDS-PAGE Analysis of Purified, BSA-Free CD6 Antibody (clone SPV-L14). Confirmation of Integrity and Purity of the Antibody.