313009

antibody from BioLegend
Targeting: CD40 Bp50, p50, TNFRSF5
Provider product page for 313009
Flow cytometry
Other assay

Antibody data

Product number
313009 - Provider product page
Provider
BioLegend
Proper citation
BioLegend Cat#313009, RRID:AB_314972
Product name
LEAF™ Purified anti-human CD40 [HB14]
Antibody type
Monoclonal
Antigen
CD40
Description
CD40 is a 48 kD type I glycoprotein also known as BP50. It is a member of the TNFR superfamily primarily expressed on B cells, macrophages, follicular dendritic cells, endothelial cells, fibroblasts, and at low levels on plasma cells. CD40 has been reported to be involved in B cell differentiation, costimulation, isotype class-switching, and protection of B cells from apoptosis. Additionally, CD40 is important for T cell-B cell interactions. The ligand of CD40 is CD154 (CD40 ligand). The HB14 antibody has been reported to promote B cell proliferation in the presence of anti-IgM, IL-4 or PMA, partially block CD40 binding to CD40L and rescue B cells from apoptosis.
Reactivity
Human, Simian
Host
Mouse
Conjugate
Unconjugated
Isotype
IgG
Vial size
50 µg
Concentration
1 mg/ml
Storage
The antibody solution should be stored undiluted at 4 °C. This LEAF™ solution contains no preservative; handle under aseptic conditions.
CD40 protein structure - 313009 shown in red.