Antibody data
- Antibody Data
- Antigen structure
- References [1]
- Comments [0]
- Validations
- Flow cytometry [1]
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Validation data
Reference
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- Product number
- 336707 - Provider product page
- Provider
- BioLegend
- Proper citation
- BioLegend Cat#336707, RRID:AB_2075176
- Product name
- PE anti-human CD48
- Antibody type
- Monoclonal
- Antigen
- CD48
- Description
- CD48 is a 40-47 kD GPI-anchored membrane protein, also known as Blast-1 and HuLy-m3. It is a member of the CD2 family that contains 2 IgSF domains and is widely expressed on both resting and activated hematopoietic cells with the exception of granulocytes, platelets, and erythrocytes. CD48 binds to CD2 at a considerably (>100-fold) lower affinity than CD58. It is thought to contribute to T cell activation. The cytoplasmic tail of CD48 has been shown to bind to the kinases Lck and Fyn.
- Reactivity
- Human
- Host
- Mouse
- Conjugate
- Yellow dye
- Isotype
- IgG
- Vial size
- 25 tests
- Storage
- The antibody solution should be stored undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Submitted references Natural killer cell-produced IFN-γ and TNF-α induce target cell cytolysis through up-regulation of ICAM-1.
Wang R, Jaw JJ, Stutzman NC, Zou Z, Sun PD
Journal of leukocyte biology 2012 Feb;91(2):299-309
Journal of leukocyte biology 2012 Feb;91(2):299-309
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Supportive validation
- Submitted by
- BioLegend (provider)
- Main image
- Experimental details
- Human peripheral blood lymphocytes stained with BJ40 PE
- Conjugate
- Yellow dye