Ab119615

antibody from Aladdin Scientific Corporation

Targeting: CDKN1A CAP20, CDKN1, CIP1, P21, p21CIP1, p21Cip1/Waf1, SDI1, WAF1

Western blot (Data presented on provider website)

Antibody Data

Product number

Ab119615

Provider

Aladdin Scientific Corporation

Product name

Recombinant p21 Antibody

Antibody type

Recombinant

Description

Rabbit anti Human p21 Antibody, Recombinant (R07-3K5), could be used for WB and so on.Application:WB: 1/500-1/1000Protein FunctionMay be the important intermediate by which p53/TP53 mediates its role as an inhibitor of cellular proliferation in response to DNA damage. Binds to and inhibits cyclin-dependent kinase activity, preventing phosphorylation of critical cyclin-dependent kinase substrates and blocking cell cycle progression. Functions in the nuclear localization and assembly of cyclin D-CDK4 complex and promotes its kinase activity towards RB1. At higher stoichiometric ratios, inhibits the kinase activity of the cyclin D-CDK4 complex.

Reactivity

Human, Mouse

Host

Rabbit

Conjugate

Unconjugated

Antigen sequence

AA 148-164


Antibody clone number

R07-3K5

Vial size

100μl,10μl,1ml,50μl

Concentration

1,5 mg/ml

Storage

Store at 4°C short term (1-2 weeks). Store at -20°C long term (24 months). Upon delivery aliquot. Avoid freeze/thaw cycle.