Antibody data
- Antibody Data
- Antigen structure
- References [9]
- Comments [0]
- Validations
- Immunohistochemistry [2]
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Validation data
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- Product number
- 17609-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#17609-1-AP, RRID:AB_2305350
- Product name
- AKT2 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated AKT2 antibody (Cat. #17609-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, IP, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references miR-29b-3p Increases Radiosensitivity in Stemness Cancer Cells via Modulating Oncogenes Axis.
Akt3-mTOR regulates hippocampal neurogenesis in adult mouse.
YTHDF1 promotes hepatocellular carcinoma progression via activating PI3K/AKT/mTOR signaling pathway and inducing epithelial-mesenchymal transition.
Asparagine reinforces mTORC1 signaling to boost thermogenesis and glycolysis in adipose tissues.
PWWP2B Fine-Tunes Adipose Thermogenesis by Stabilizing HDACs in a NuRD Subcomplex.
Regulation of MicroRNA-497-Targeting AKT2 Influences Tumor Growth and Chemoresistance to Cisplatin in Lung Cancer.
AKT2 drives cancer progression and is negatively modulated by miR-124 in human lung adenocarcinoma.
Estrogen regulates miRNA expression: implication of estrogen receptor and miR-124/AKT2 in tumor growth and angiogenesis.
MicroRNA-137 Contributes to Dampened Tumorigenesis in Human Gastric Cancer by Targeting AKT2.
Pan D, Du Y, Li R, Shen A, Liu X, Li C, Hu B
Frontiers in cell and developmental biology 2021;9:741074
Frontiers in cell and developmental biology 2021;9:741074
Akt3-mTOR regulates hippocampal neurogenesis in adult mouse.
Zhang T, Ding H, Wang Y, Yuan Z, Zhang Y, Chen G, Xu Y, Chen L
Journal of neurochemistry 2021 Nov;159(3):498-511
Journal of neurochemistry 2021 Nov;159(3):498-511
YTHDF1 promotes hepatocellular carcinoma progression via activating PI3K/AKT/mTOR signaling pathway and inducing epithelial-mesenchymal transition.
Luo X, Cao M, Gao F, He X
Experimental hematology & oncology 2021 Jun 4;10(1):35
Experimental hematology & oncology 2021 Jun 4;10(1):35
Asparagine reinforces mTORC1 signaling to boost thermogenesis and glycolysis in adipose tissues.
Xu Y, Shi T, Cui X, Yan L, Wang Q, Xu X, Zhao Q, Xu X, Tang QQ, Tang H, Pan D
The EMBO journal 2021 Dec 15;40(24):e108069
The EMBO journal 2021 Dec 15;40(24):e108069
PWWP2B Fine-Tunes Adipose Thermogenesis by Stabilizing HDACs in a NuRD Subcomplex.
Yan L, Jin W, Zhao Q, Cui X, Shi T, Xu Y, Li F, Jin W, Zhang Z, Zhang Z, Tang QQ, Pan D
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2021 Aug;8(16):e2102060
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2021 Aug;8(16):e2102060
Regulation of MicroRNA-497-Targeting AKT2 Influences Tumor Growth and Chemoresistance to Cisplatin in Lung Cancer.
Wang L, Ji XB, Wang LH, Qiu JG, Zhou FM, Liu WJ, Wan DD, Lin MC, Liu LZ, Zhang JY, Jiang BH
Frontiers in cell and developmental biology 2020;8:840
Frontiers in cell and developmental biology 2020;8:840
AKT2 drives cancer progression and is negatively modulated by miR-124 in human lung adenocarcinoma.
Liu T, Zhu J, Du W, Ning W, Zhang Y, Zeng Y, Liu Z, Huang JA
Respiratory research 2020 Sep 1;21(1):227
Respiratory research 2020 Sep 1;21(1):227
Estrogen regulates miRNA expression: implication of estrogen receptor and miR-124/AKT2 in tumor growth and angiogenesis.
Jiang CF, Li DM, Shi ZM, Wang L, Liu MM, Ge X, Liu X, Qian YC, Wen YY, Zhen LL, Lin J, Liu LZ, Jiang BH
Oncotarget 2016 Jun 14;7(24):36940-36955
Oncotarget 2016 Jun 14;7(24):36940-36955
MicroRNA-137 Contributes to Dampened Tumorigenesis in Human Gastric Cancer by Targeting AKT2.
Wu L, Chen J, Ding C, Wei S, Zhu Y, Yang W, Zhang X, Wei X, Han D
PloS one 2015;10(6):e0130124
PloS one 2015;10(6):e0130124
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human liver using 17609-1-AP(AKT2 antibody) at dilution of 1:100 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The AKT2 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human AKT2. This antibody recognizes human,mouse,rat antigen. The AKT2 antibody has been validated for the following applications: ELISA, IHC analysis.