Antibody data
- Antibody Data
- Antigen structure
- References [38]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [2]
Submit
Validation data
Reference
Comment
Report error
- Product number
- bs-0127R - Provider product page
- Provider
- Bioss
- Proper citation
- Bioss Cat#bs-0127R, RRID:AB_10856348
- Product name
- Bax Polyclonal Antibody
- Antibody type
- Polyclonal
- Description
- KLH conjugated synthetic peptide derived from human Bax
- Reactivity
- Human, Mouse, Rat, Porcine, Rabbit
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 100ul
- Concentration
- 1ug/ul
- Storage
- Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for 12 months.
Submitted references The proteasome activator REGγ counteracts immunoproteasome expression and autoimmunity.
miR-193a/b-3p relieves hepatic fibrosis and restrains proliferation and activation of hepatic stellate cells.
Polychlorinated Biphenyl Quinone Induces Caspase 1-Mediated Pyroptosis through Induction of Pro-inflammatory HMGB1-TLR4-NLRP3-GSDMD Signal Axis.
LncRNA XIST mediates bovine mammary epithelial cell inflammatory response via NF-κB/NLRP3 inflammasome pathway.
CRISPR-Cas9 targeting of MMP13 in human chondrocytes leads to significantly reduced levels of the metalloproteinase and enhanced type II collagen accumulation.
Long-term arsenite exposure induces testicular toxicity by redox imbalance, G2/M cell arrest and apoptosis in mice.
Deficiency of stress-associated gene Nupr1 increases bone volume by attenuating differentiation of osteoclasts and enhancing differentiation of osteoblasts.
Desumoylating Isopeptidase 2 (DESI2) Inhibits Proliferation and Promotes Apoptosis of Pancreatic Cancer Cells through Regulating PI3K/AKT/mTOR Signaling Pathway.
Dietary Sea Buckthorn Pomace Induces Beige Adipocyte Formation in Inguinal White Adipose Tissue in Lambs.
Harmine mitigates LPS-induced acute kidney injury through inhibition of the TLR4-NF-κB/NLRP3 inflammasome signalling pathway in mice.
A Novel Rat Model of Patellofemoral Osteoarthritis Due to Patella Baja, or Low-Lying Patella.
Anti-Inflammatory Effects of High Hydrostatic Pressure Extract of Mulberry (Morus alba) Fruit on LPS-Stimulated RAW264.7 Cells.
TFF3 Contributes to Epithelial-Mesenchymal Transition (EMT) in Papillary Thyroid Carcinoma Cells via the MAPK/ERK Signaling Pathway.
High Concentration of Aspirin Induces Apoptosis in Rat Tendon Stem Cells via Inhibition of the Wnt/β-Catenin Pathway.
Downregulation of cytoplasmic DNases is implicated in cytoplasmic DNA accumulation and SASP in senescent cells.
Expression of Pref-1 and Related Chemokines during theDevelopment of Rat Mesenteric Lymph Nodes.
Combination therapy with F5/35 fiber chimeric conditionally replicative adenoviruses expressing IL-24 enhances the antitumor effect of temozolomide against melanoma.
miR-1307-3p suppresses the chondrogenic differentiation of human adipose-derived stem cells by targeting BMPR2.
Signaling pathways involved in the expression of SZNF and the target genes binding with SZNF related to cyadox.
Effects of ginsenoside Rb1 on oxidative stress injury in rat spinal cords by regulating the eNOS/Nrf2/HO-1 signaling pathway.
Engineering human cell spheroids to model embryonic tissue fusion in vitro.
Curcumin attenuates the development of thoracic aortic aneurysm by inhibiting VEGF expression and inflammation.
The inhibitory effect of anti- tumor polysaccharide from Punica granatum on metastasis.
Phycocyanin attenuates pulmonary fibrosis via the TLR2-MyD88-NF-κB signaling pathway.
Polyphenol-rich fraction of Parquetina nigrescens mitigates dichlorvos-induced neurotoxicity and apoptosis.
MicroRNA-125a-3p is involved in early behavioral disorders in stroke-afflicted rats through the regulation of Cadm2.
Unconventional MAPK-GSK-3β Pathway Behind Atypical Epithelial-Mesenchymal Transition In Hepatocellular Carcinoma.
Platelet-rich plasma protects rat chondrocytes from interleukin-1β-induced apoptosis.
The molecular mechanism of G2M cell cycle arrest induced by AFB1 in the jejunum.
The correlation between microRNA490-3p and TGFα in endometrial carcinoma tumorigenesis and progression.
YAP1 enhances cell proliferation, migration, and invasion of gastric cancer in vitro and in vivo.
Crude Preparations of Helicobacter pylori Outer Membrane Vesicles Induce Upregulation of Heme Oxygenase-1 via Activating Akt-Nrf2 and mTOR-IκB Kinase-NF-κB Pathways in Dendritic Cells.
Canonical Wnt signaling pathway contributes to the proliferation and survival in porcine pancreatic stem cells (PSCs).
Sialic acid rescues repurified lipopolysaccharide-induced acute renal failure via inhibiting TLR4/PKC/gp91-mediated endoplasmic reticulum stress, apoptosis, autophagy, and pyroptosis signaling.
Rapamycin inhibits acrolein-induced apoptosis by alleviating ROS-driven mitochondrial dysfunction in male germ cells.
Heparanase and vascular endothelial growth factor expression is increased in hypoxia-induced retinal neovascularization.
Targeting SPARC by lentivirus-mediated RNA interference inhibits cervical cancer cell growth and metastasis.
Intraocular expression of serum amyloid a and interleukin-6 in proliferative diabetic retinopathy.
Yao L, Zhou L, Xuan Y, Zhang P, Wang X, Wang T, Meng T, Xue Y, Ma X, Shah AS, Shang S, Ma X, Xie W, Wang H, Fu Q, Xia Y, Moses RE, Wang H, Li L, Xiao J, Zhang B, Li X
Journal of autoimmunity 2019 Sep;103:102282
Journal of autoimmunity 2019 Sep;103:102282
miR-193a/b-3p relieves hepatic fibrosis and restrains proliferation and activation of hepatic stellate cells.
Ju B, Nie Y, Yang X, Wang X, Li F, Wang M, Wang C, Zhang H
Journal of cellular and molecular medicine 2019 Jun;23(6):3824-3832
Journal of cellular and molecular medicine 2019 Jun;23(6):3824-3832
Polychlorinated Biphenyl Quinone Induces Caspase 1-Mediated Pyroptosis through Induction of Pro-inflammatory HMGB1-TLR4-NLRP3-GSDMD Signal Axis.
Dong W, Zhu Q, Yang B, Qin Q, Wang Y, Xia X, Zhu X, Liu Z, Song E, Song Y
Chemical research in toxicology 2019 Jun 17;32(6):1051-1057
Chemical research in toxicology 2019 Jun 17;32(6):1051-1057
LncRNA XIST mediates bovine mammary epithelial cell inflammatory response via NF-κB/NLRP3 inflammasome pathway.
Ma M, Pei Y, Wang X, Feng J, Zhang Y, Gao MQ
Cell proliferation 2019 Jan;52(1):e12525
Cell proliferation 2019 Jan;52(1):e12525
CRISPR-Cas9 targeting of MMP13 in human chondrocytes leads to significantly reduced levels of the metalloproteinase and enhanced type II collagen accumulation.
Seidl CI, Fulga TA, Murphy CL
Osteoarthritis and cartilage 2019 Jan;27(1):140-147
Osteoarthritis and cartilage 2019 Jan;27(1):140-147
Long-term arsenite exposure induces testicular toxicity by redox imbalance, G2/M cell arrest and apoptosis in mice.
Zeng Q, Yi H, Huang L, An Q, Wang H
Toxicology 2019 Jan 1;411:122-132
Toxicology 2019 Jan 1;411:122-132
Deficiency of stress-associated gene Nupr1 increases bone volume by attenuating differentiation of osteoclasts and enhancing differentiation of osteoblasts.
Shiraki M, Xu X, Iovanna JL, Kukita T, Hirata H, Kamohara A, Kubota Y, Miyamoto H, Mawatari M, Kukita A
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 Aug;33(8):8836-8852
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 Aug;33(8):8836-8852
Desumoylating Isopeptidase 2 (DESI2) Inhibits Proliferation and Promotes Apoptosis of Pancreatic Cancer Cells through Regulating PI3K/AKT/mTOR Signaling Pathway.
Ou X, Zhang GT, Xu Z, Chen JS, Xie Y, Liu JK, Liu XP
Pathology oncology research : POR 2019 Apr;25(2):635-646
Pathology oncology research : POR 2019 Apr;25(2):635-646
Dietary Sea Buckthorn Pomace Induces Beige Adipocyte Formation in Inguinal White Adipose Tissue in Lambs.
Zhang T, Deng B, Zhang R, Qin X, Zhang J, Zhao J
Animals : an open access journal from MDPI 2019 Apr 24;9(4)
Animals : an open access journal from MDPI 2019 Apr 24;9(4)
Harmine mitigates LPS-induced acute kidney injury through inhibition of the TLR4-NF-κB/NLRP3 inflammasome signalling pathway in mice.
Niu X, Yao Q, Li W, Zang L, Li W, Zhao J, Liu F, Zhi W
European journal of pharmacology 2019 Apr 15;849:160-169
European journal of pharmacology 2019 Apr 15;849:160-169
A Novel Rat Model of Patellofemoral Osteoarthritis Due to Patella Baja, or Low-Lying Patella.
Bei M, Tian F, Liu N, Zheng Z, Cao X, Zhang H, Wang Y, Xiao Y, Dai M, Zhang L
Medical science monitor : international medical journal of experimental and clinical research 2019 Apr 13;25:2702-2717
Medical science monitor : international medical journal of experimental and clinical research 2019 Apr 13;25:2702-2717
Anti-Inflammatory Effects of High Hydrostatic Pressure Extract of Mulberry (Morus alba) Fruit on LPS-Stimulated RAW264.7 Cells.
Jung S, Lee MS, Choi AJ, Kim CT, Kim Y
Molecules (Basel, Switzerland) 2019 Apr 11;24(7)
Molecules (Basel, Switzerland) 2019 Apr 11;24(7)
TFF3 Contributes to Epithelial-Mesenchymal Transition (EMT) in Papillary Thyroid Carcinoma Cells via the MAPK/ERK Signaling Pathway.
Lin X, Zhang H, Dai J, Zhang W, Zhang J, Xue G, Wu J
Journal of Cancer 2018;9(23):4430-4439
Journal of Cancer 2018;9(23):4430-4439
High Concentration of Aspirin Induces Apoptosis in Rat Tendon Stem Cells via Inhibition of the Wnt/β-Catenin Pathway.
Wang Y, Tang H, He G, Shi Y, Kang X, Lyu J, Zhou M, Zhu M, Zhang J, Tang K
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;50(6):2046-2059
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;50(6):2046-2059
Downregulation of cytoplasmic DNases is implicated in cytoplasmic DNA accumulation and SASP in senescent cells.
Takahashi A, Loo TM, Okada R, Kamachi F, Watanabe Y, Wakita M, Watanabe S, Kawamoto S, Miyata K, Barber GN, Ohtani N, Hara E
Nature communications 2018 Mar 28;9(1):1249
Nature communications 2018 Mar 28;9(1):1249
Expression of Pref-1 and Related Chemokines during theDevelopment of Rat Mesenteric Lymph Nodes.
Peng Y, Jia LM, Li BX, Xie LP, Xie ZJ, Zheng JH
Biomedical and environmental sciences : BES 2018 Jul;31(7):507-514
Biomedical and environmental sciences : BES 2018 Jul;31(7):507-514
Combination therapy with F5/35 fiber chimeric conditionally replicative adenoviruses expressing IL-24 enhances the antitumor effect of temozolomide against melanoma.
Yang M, Yang C, Tao Y, Tang J, Huang Q, Guo W, Feng S, Jiang A, Xu X, Jiang G, Liu Y
Cancer medicine 2018 Dec;7(12):5928-5942
Cancer medicine 2018 Dec;7(12):5928-5942
miR-1307-3p suppresses the chondrogenic differentiation of human adipose-derived stem cells by targeting BMPR2.
Yang Z, Li R, Ao J, Wa QD, Zhang Y, Chen L, Wen J, Chen B, Pan W, Li B, Tian XB
International journal of molecular medicine 2018 Dec;42(6):3115-3124
International journal of molecular medicine 2018 Dec;42(6):3115-3124
Signaling pathways involved in the expression of SZNF and the target genes binding with SZNF related to cyadox.
Cui L, Xing D, Huang D, Li D, Lu Q, Wang X, Wang Y, Huang L, Cheng G, Hao H, Peng D, Liu Z, Dai M, Yuan Z
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Dec;108:1879-1893
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Dec;108:1879-1893
Effects of ginsenoside Rb1 on oxidative stress injury in rat spinal cords by regulating the eNOS/Nrf2/HO-1 signaling pathway.
Liu X, Gu X, Yu M, Zi Y, Yu H, Wang Y, Xie Y, Xiang L
Experimental and therapeutic medicine 2018 Aug;16(2):1079-1086
Experimental and therapeutic medicine 2018 Aug;16(2):1079-1086
Engineering human cell spheroids to model embryonic tissue fusion in vitro.
Belair DG, Wolf CJ, Wood C, Ren H, Grindstaff R, Padgett W, Swank A, MacMillan D, Fisher A, Winnik W, Abbott BD
PloS one 2017;12(9):e0184155
PloS one 2017;12(9):e0184155
Curcumin attenuates the development of thoracic aortic aneurysm by inhibiting VEGF expression and inflammation.
Li X, Fang Q, Tian X, Wang X, Ao Q, Hou W, Tong H, Fan J, Bai S
Molecular medicine reports 2017 Oct;16(4):4455-4462
Molecular medicine reports 2017 Oct;16(4):4455-4462
The inhibitory effect of anti- tumor polysaccharide from Punica granatum on metastasis.
Varghese S, Joseph MM, S R A, B S U, Sreelekha TT
International journal of biological macromolecules 2017 Oct;103:1000-1010
International journal of biological macromolecules 2017 Oct;103:1000-1010
Phycocyanin attenuates pulmonary fibrosis via the TLR2-MyD88-NF-κB signaling pathway.
Li C, Yu Y, Li W, Liu B, Jiao X, Song X, Lv C, Qin S
Scientific reports 2017 Jul 19;7(1):5843
Scientific reports 2017 Jul 19;7(1):5843
Polyphenol-rich fraction of Parquetina nigrescens mitigates dichlorvos-induced neurotoxicity and apoptosis.
Ochigbo GO, Saba AB, Oyagbemi AA, Omobowale TO, Asenuga ER
Journal of Ayurveda and integrative medicine 2017 Jan - Mar;8(1):27-36
Journal of Ayurveda and integrative medicine 2017 Jan - Mar;8(1):27-36
MicroRNA-125a-3p is involved in early behavioral disorders in stroke-afflicted rats through the regulation of Cadm2.
Liu Y, Li Y, Ren Z, Si W, Li Y, Wei G, Zhao W, Zhou J, Tian Y, Chen D
International journal of molecular medicine 2017 Dec;40(6):1851-1859
International journal of molecular medicine 2017 Dec;40(6):1851-1859
Unconventional MAPK-GSK-3β Pathway Behind Atypical Epithelial-Mesenchymal Transition In Hepatocellular Carcinoma.
Parveen S, Vedagiri D, Nair HG, Parthasarathy H, Harshan KH
Scientific reports 2017 Aug 18;7(1):8842
Scientific reports 2017 Aug 18;7(1):8842
Platelet-rich plasma protects rat chondrocytes from interleukin-1β-induced apoptosis.
Yang J, Lu Y, Guo A
Molecular medicine reports 2016 Nov;14(5):4075-4082
Molecular medicine reports 2016 Nov;14(5):4075-4082
The molecular mechanism of G2M cell cycle arrest induced by AFB1 in the jejunum.
Yin H, Jiang M, Peng X, Cui H, Zhou Y, He M, Zuo Z, Ouyang P, Fan J, Fang J
Oncotarget 2016 Jun 14;7(24):35592-35606
Oncotarget 2016 Jun 14;7(24):35592-35606
The correlation between microRNA490-3p and TGFα in endometrial carcinoma tumorigenesis and progression.
Sun KX, Chen Y, Chen S, Liu BL, Feng MX, Zong ZH, Zhao Y
Oncotarget 2016 Feb 23;7(8):9236-49
Oncotarget 2016 Feb 23;7(8):9236-49
YAP1 enhances cell proliferation, migration, and invasion of gastric cancer in vitro and in vivo.
Sun D, Li X, He Y, Li W, Wang Y, Wang H, Jiang S, Xin Y
Oncotarget 2016 Dec 6;7(49):81062-81076
Oncotarget 2016 Dec 6;7(49):81062-81076
Crude Preparations of Helicobacter pylori Outer Membrane Vesicles Induce Upregulation of Heme Oxygenase-1 via Activating Akt-Nrf2 and mTOR-IκB Kinase-NF-κB Pathways in Dendritic Cells.
Ko SH, Rho DJ, Jeon JI, Kim YJ, Woo HA, Kim N, Kim JM
Infection and immunity 2016 Aug;84(8):2162-2174
Infection and immunity 2016 Aug;84(8):2162-2174
Canonical Wnt signaling pathway contributes to the proliferation and survival in porcine pancreatic stem cells (PSCs).
He X, Han W, Hu SX, Zhang MZ, Hua JL, Peng S
Cell and tissue research 2015 Nov;362(2):379-88
Cell and tissue research 2015 Nov;362(2):379-88
Sialic acid rescues repurified lipopolysaccharide-induced acute renal failure via inhibiting TLR4/PKC/gp91-mediated endoplasmic reticulum stress, apoptosis, autophagy, and pyroptosis signaling.
Yang CC, Yao CA, Yang JC, Chien CT
Toxicological sciences : an official journal of the Society of Toxicology 2014 Sep;141(1):155-65
Toxicological sciences : an official journal of the Society of Toxicology 2014 Sep;141(1):155-65
Rapamycin inhibits acrolein-induced apoptosis by alleviating ROS-driven mitochondrial dysfunction in male germ cells.
He X, Song W, Liu C, Chen S, Hua J
Cell proliferation 2014 Apr;47(2):161-71
Cell proliferation 2014 Apr;47(2):161-71
Heparanase and vascular endothelial growth factor expression is increased in hypoxia-induced retinal neovascularization.
Hu J, Song X, He YQ, Freeman C, Parish CR, Yuan L, Yu H, Tang S
Investigative ophthalmology & visual science 2012 Oct 3;53(11):6810-7
Investigative ophthalmology & visual science 2012 Oct 3;53(11):6810-7
Targeting SPARC by lentivirus-mediated RNA interference inhibits cervical cancer cell growth and metastasis.
Chen J, Shi D, Liu X, Fang S, Zhang J, Zhao Y
BMC cancer 2012 Oct 10;12:464
BMC cancer 2012 Oct 10;12:464
Intraocular expression of serum amyloid a and interleukin-6 in proliferative diabetic retinopathy.
Ma Y, Tao Y, Lu Q, Jiang YR
American journal of ophthalmology 2011 Oct;152(4):678-685.e2
American journal of ophthalmology 2011 Oct;152(4):678-685.e2
No comments: Submit comment
Supportive validation
- Submitted by
- Bioss (provider)
- Main image
- Experimental details
- L1 rat brain, L2 mouse liver lysates probed (bs-0127R) at 1:200 in 4°C. Followed by conjugation to secondary antibody (bs-0295G-HRP) at 1:3000 90min in 37°C. Predicted band and observed band size: 21kDa.
- Sample type
- Mouse
- Other comments
- Liver
Supportive validation
- Submitted by
- Bioss (provider)
- Main image
- Experimental details
- Formalin-fixed and paraffin embedded: rat brain tissue labeled with Anti-Bax Polyclonal Antibody, Unconjugated (bs-0127R) at 1:800 followed by conjugation to the secondary antibody and DAB staining
- Sample type
- Rat
- Other comments
- Brain
- Submitted by
- Bioss (provider)
- Main image
- Experimental details
- Formalin-fixed and paraffin embedded rabbit brain tissue labeled with Anti-Bax Polyclonal Antibody, Unconjugated (bs-0127R) at 1:200 followed by conjugation to the secondary antibody and DAB staining
- Sample type
- Rabbit
- Other comments
- Brain