Antibody data
- Antibody Data
- Antigen structure
- References [8]
- Comments [0]
- Validations
- Western blot [4]
- Immunohistochemistry [2]
- Flow cytometry [1]
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- Product number
- ABIN388094 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-BCL2-Associated X Protein (BAX) (AA 41-76), (BH3 Domain) antibody
- Antibody type
- Polyclonal
- Description
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
- Reactivity
- Human
- Host
- Rabbit
- Epitope
- AA 41-76, BH3 Domain
- Antibody clone number
- RB0952
- Vial size
- 400 μL
- Storage
- Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Submitted references Oridonin phosphate-induced autophagy effectively enhances cell apoptosis of human breast cancer cells.
BH3-triggered structural reorganization drives the activation of proapoptotic BAX.
Ceramide 1-phosphate inhibits serine palmitoyltransferase and blocks apoptosis in alveolar macrophages.
Protein kinase Cepsilon interacts with Bax and promotes survival of human prostate cancer cells.
Bax conformational change is a crucial step for PUMA-mediated apoptosis in human leukemia.
Cytosolic prion protein is not toxic and protects against Bax-mediated cell death in human primary neurons.
Cleavage of Bax to p18 Bax accelerates stress-induced apoptosis, and a cathepsin-like protease may rapidly degrade p18 Bax.
Cathepsin D triggers Bax activation, resulting in selective apoptosis-inducing factor (AIF) relocation in T lymphocytes entering the early commitment phase to apoptosis.
Li Y, Wang Y, Wang S, Gao Y, Zhang X, Lu C
Medical oncology (Northwood, London, England) 2015 Jan;32(1):365
Medical oncology (Northwood, London, England) 2015 Jan;32(1):365
BH3-triggered structural reorganization drives the activation of proapoptotic BAX.
Gavathiotis E, Reyna DE, Davis ML, Bird GH, Walensky LD
Molecular cell 2010 Nov 12;40(3):481-92
Molecular cell 2010 Nov 12;40(3):481-92
Ceramide 1-phosphate inhibits serine palmitoyltransferase and blocks apoptosis in alveolar macrophages.
Granado MH, Gangoiti P, Ouro A, Arana L, Gómez-Muñoz A
Biochimica et biophysica acta 2009 Apr;1791(4):263-72
Biochimica et biophysica acta 2009 Apr;1791(4):263-72
Protein kinase Cepsilon interacts with Bax and promotes survival of human prostate cancer cells.
McJilton MA, Van Sikes C, Wescott GG, Wu D, Foreman TL, Gregory CW, Weidner DA, Harris Ford O, Morgan Lasater A, Mohler JL, Terrian DM
Oncogene 2003 Sep 11;22(39):7958-68
Oncogene 2003 Sep 11;22(39):7958-68
Bax conformational change is a crucial step for PUMA-mediated apoptosis in human leukemia.
Liu FT, Newland AC, Jia L
Biochemical and biophysical research communications 2003 Oct 24;310(3):956-62
Biochemical and biophysical research communications 2003 Oct 24;310(3):956-62
Cytosolic prion protein is not toxic and protects against Bax-mediated cell death in human primary neurons.
Roucou X, Guo Q, Zhang Y, Goodyer CG, LeBlanc AC
The Journal of biological chemistry 2003 Oct 17;278(42):40877-81
The Journal of biological chemistry 2003 Oct 17;278(42):40877-81
Cleavage of Bax to p18 Bax accelerates stress-induced apoptosis, and a cathepsin-like protease may rapidly degrade p18 Bax.
Cao X, Deng X, May WS
Blood 2003 Oct 1;102(7):2605-14
Blood 2003 Oct 1;102(7):2605-14
Cathepsin D triggers Bax activation, resulting in selective apoptosis-inducing factor (AIF) relocation in T lymphocytes entering the early commitment phase to apoptosis.
Bidère N, Lorenzo HK, Carmona S, Laforge M, Harper F, Dumont C, Senik A
The Journal of biological chemistry 2003 Aug 15;278(33):31401-11
The Journal of biological chemistry 2003 Aug 15;278(33):31401-11
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- FACS