Ab102233

antibody from Aladdin Scientific Corporation

Targeting: MAPK1 ERK, ERK2, MAPK2, p41mapk, PRKM1, PRKM2

Western blot (Data presented on provider website)

Immunocytochemistry (Data presented on provider website)

Immunohistochemistry (Data presented on provider website)

Antibody Data

Product number

Ab102233

Provider

Aladdin Scientific Corporation

Product name

Recombinant ERK2 Antibody

Antibody type

Recombinant

Description

Rabbit anti Human ERK2 Antibody, Recombinant (R07-1A9), could be used for WB, IHC, IF, ICC and so on.Application:WB: 1/500-1/1000IHC: 1/50-1/100IF/ICC: 1/50-1/200Protein FunctionInvolved in both the initiation and regulation of meiosis, mitosis, and postmitotic functions in differentiated cells by phosphorylating a number of transcription factors such as ELK1. Phosphorylates EIF4EBP1; required for initiation of translation. Phosphorylates microtubule-associated protein 2 (MAP2). Phosphorylates SPZ1 (By similarity). Phosphorylates heat shock factor protein 4 (HSF4) and ARHGEF2. Acts as a transcriptional repressor. Binds to a [GC]AAA[GC] consensus sequence. Repress the expression of interferon gamma-induced genes. Seems to bind to the promoter of CCL5, DMP1, IFIH1, IFITM1, IRF7, IRF9, LAMP3, OAS1, OAS2, OAS3 and STAT1. Transcriptional activity is independent of kinase activity.

Reactivity

Human, Mouse, Rat

Host

Rabbit

Conjugate

Unconjugated

Antigen sequence

AA 340-360


Epitope

reacts with an epitope located in the C terminal region of ERK2.

Antibody clone number

R07-1A9

Vial size

100μl,10μl,1ml,50μl

Concentration

0,5 mg/ml

Storage

Store at 4°C short term (1-2 weeks). Store at -20°C long term (24 months). Upon delivery aliquot. Avoid freeze/thaw cycle.