BS8048

antibody from Bioworld Technology, Inc

Targeting: LAMC2 BM600-100kDa, EBR2, EBR2A, kalinin-105kDa, LAMB2T, LAMNB2, nicein-100kDa

Western blot (Data presented on provider website)

Antibody Data

Product number

BS8048

Provider

Bioworld Technology, Inc

Product name

LAMC2 polyclonal antibody

Antibody type

Polyclonal

Antigen

Recombinant full length Human LAMC2.

Description

Laminins are essential and abundant structural non-collagenous glycoproteins localizing to basement membranes. Basement membranes (cell-associated extracellular matrices (ECMs)) are polymers of laminins with stabilizing Type IV Collagen networks, nidogen and several proteoglycans. Basement membranes are found under epithelial layers, around the endothelium of blood vessels, and surrounding muscle, peripheral nerve and fat cells. Formation of basement membranes influences cell proliferation, phenotype, migration, gene expression and tissue architecture. Each laminin is a heterotrimer of ?, ? and ? chain subunits that undergoes cell-secretion and incorporation into the ECM. Laminins can self-assemble, bind to other matrix macromolecules, and have unique and shared cell interactions mediated by Integrins, dystroglycan and cognate laminin receptors. The human Laminin g-2 gene maps to chromosome 1q25.3 and specifically localizes to epithelial cells in skin, lung and kidney.

Reactivity

Human, Mouse, Rat

Host

Rabbit

Isotype

IgG

Vial size

100ul

Concentration

1 mg/ml

Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.