Antibody data
- Antibody Data
- Antigen structure
- References [6]
- Comments [0]
- Validations [0]
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- Product number
- ABIN362491 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Pyruvate Dehydrogenase Kinase, Isozyme 1 (PDK1) (AA 239-243) antibody
- Antibody type
- Polyclonal
- Antigen
- Peptide sequence around AA 239-243 (A-N-S-F-V) derived from Human PDK1. Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates.
- Description
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography usingepitope-specific immunogen.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Epitope
- AA 239-243
- Isotype
- IgG
- Vial size
- 50 μL
- Concentration
- 1 mg/mL
- Storage
- Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
Submitted references Activation of mammalian target of rapamycin pathway confers adverse outcome in nonsmall cell lung carcinoma.
Phosphoinositide-dependent phosphorylation of PDK1 regulates nuclear translocation.
Large-scale characterization of HeLa cell nuclear phosphoproteins.
Nuclear translocation of 3'-phosphoinositide-dependent protein kinase 1 (PDK-1): a potential regulatory mechanism for PDK-1 function.
Regulation of kinase activity of 3-phosphoinositide-dependent protein kinase-1 by binding to 14-3-3.
Insulin stimulates increased catalytic activity of phosphoinositide-dependent kinase-1 by a phosphorylation-dependent mechanism.
Liu D, Huang Y, Chen B, Zeng J, Guo N, Zhang S, Liu L, Xu H, Mo X, Li W
Cancer 2011 Aug 15;117(16):3763-73
Cancer 2011 Aug 15;117(16):3763-73
Phosphoinositide-dependent phosphorylation of PDK1 regulates nuclear translocation.
Scheid MP, Parsons M, Woodgett JR
Molecular and cellular biology 2005 Mar;25(6):2347-63
Molecular and cellular biology 2005 Mar;25(6):2347-63
Large-scale characterization of HeLa cell nuclear phosphoproteins.
Beausoleil SA, Jedrychowski M, Schwartz D, Elias JE, Villén J, Li J, Cohn MA, Cantley LC, Gygi SP
Proceedings of the National Academy of Sciences of the United States of America 2004 Aug 17;101(33):12130-5
Proceedings of the National Academy of Sciences of the United States of America 2004 Aug 17;101(33):12130-5
Nuclear translocation of 3'-phosphoinositide-dependent protein kinase 1 (PDK-1): a potential regulatory mechanism for PDK-1 function.
Lim MA, Kikani CK, Wick MJ, Dong LQ
Proceedings of the National Academy of Sciences of the United States of America 2003 Nov 25;100(24):14006-11
Proceedings of the National Academy of Sciences of the United States of America 2003 Nov 25;100(24):14006-11
Regulation of kinase activity of 3-phosphoinositide-dependent protein kinase-1 by binding to 14-3-3.
Sato S, Fujita N, Tsuruo T
The Journal of biological chemistry 2002 Oct 18;277(42):39360-7
The Journal of biological chemistry 2002 Oct 18;277(42):39360-7
Insulin stimulates increased catalytic activity of phosphoinositide-dependent kinase-1 by a phosphorylation-dependent mechanism.
Chen H, Nystrom FH, Dong LQ, Li Y, Song S, Liu F, Quon MJ
Biochemistry 2001 Oct 2;40(39):11851-9
Biochemistry 2001 Oct 2;40(39):11851-9
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