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Learnsc-7290
antibody from Santa Cruz Biotechnology
Targeting: PLCG1
NCKAP3, PLC-II, PLC1, PLC148, PLCgamma1
Western blotAntibody data
- Antibody Data
- Antigen structure
- References [6]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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- Product number
- sc-7290 - Provider product page
- Provider
- Santa Cruz Biotechnology
- Proper citation
- Santa Cruz Biotechnology Cat#sc-7290, RRID:AB_628119
- Product name
- Anti-PLCG1
- Antibody type
- Monoclonal
- Antigen
- Synthetic peptide
- Reactivity
- Human
- Host
- Mouse
Submitted references Aberrant receptor internalization and enhanced FRS2-dependent signaling contribute to the transforming activity of the fibroblast growth factor receptor 2 IIIb C3 isoform.
Human olfactory epithelial cells generated in vitro express diverse neuronal characteristics.
Suppression of PLCbeta2 by endotoxin plays a role in the adenosine A(2A) receptor-mediated switch of macrophages from an inflammatory to an angiogenic phenotype.
Phospholipase Cgamma2 mediates RANKL-stimulated lymph node organogenesis and osteoclastogenesis.
Induction of interleukin-6 in human retinal epithelial cells by an attenuated Herpes simplex virus vector requires viral replication and NFkappaB activation.
Targeting of protein kinase C-epsilon during Fcgamma receptor-dependent phagocytosis requires the epsilonC1B domain and phospholipase C-gamma1.
Cha JY, Maddileti S, Mitin N, Harden TK, Der CJ
The Journal of biological chemistry 2009 Mar 6;284(10):6227-40
The Journal of biological chemistry 2009 Mar 6;284(10):6227-40
Human olfactory epithelial cells generated in vitro express diverse neuronal characteristics.
Borgmann-Winter KE, Rawson NE, Wang HY, Wang H, Macdonald ML, Ozdener MH, Yee KK, Gomez G, Xu J, Bryant B, Adamek G, Mirza N, Pribitkin E, Hahn CG
Neuroscience 2009 Jan 23;158(2):642-53
Neuroscience 2009 Jan 23;158(2):642-53
Suppression of PLCbeta2 by endotoxin plays a role in the adenosine A(2A) receptor-mediated switch of macrophages from an inflammatory to an angiogenic phenotype.
Grinberg S, Hasko G, Wu D, Leibovich SJ
The American journal of pathology 2009 Dec;175(6):2439-53
The American journal of pathology 2009 Dec;175(6):2439-53
Phospholipase Cgamma2 mediates RANKL-stimulated lymph node organogenesis and osteoclastogenesis.
Chen Y, Wang X, Di L, Fu G, Chen Y, Bai L, Liu J, Feng X, McDonald JM, Michalek S, He Y, Yu M, Fu YX, Wen R, Wu H, Wang D
The Journal of biological chemistry 2008 Oct 24;283(43):29593-601
The Journal of biological chemistry 2008 Oct 24;283(43):29593-601
Induction of interleukin-6 in human retinal epithelial cells by an attenuated Herpes simplex virus vector requires viral replication and NFkappaB activation.
Cai S, Brandt CR
Experimental eye research 2008 Feb;86(2):178-88
Experimental eye research 2008 Feb;86(2):178-88
Targeting of protein kinase C-epsilon during Fcgamma receptor-dependent phagocytosis requires the epsilonC1B domain and phospholipase C-gamma1.
Cheeseman KL, Ueyama T, Michaud TM, Kashiwagi K, Wang D, Flax LA, Shirai Y, Loegering DJ, Saito N, Lennartz MR
Molecular biology of the cell 2006 Feb;17(2):799-813
Molecular biology of the cell 2006 Feb;17(2):799-813
No comments: Submit comment
Supportive validation
- Submitted by
- per
- Main image
- Experimental details
- Western blot analysis of antibody specificity using a routine panel composed of IgG/HSA-depleted human plasma and protein lysates from selected human tissues and cell lines.
- Validation comment
- Band of predicted size in kDa (+/-20%) with additional bands present.
- Primary Ab dilution
- 1:500
- Secondary Ab dilution
- 1:7000
- Lane 1
- Marker [kDa]: 229, 112, 83.5, 47.9, 32.3, 26.5, 17.2
- Lane 2
- RT-4
- Lane 3
- U-251MG sp
- Lane 4
- Human Plasma
- Lane 5
- Liver
- Lane 6
- Tonsil
- Theoretical target weight
- [kDa] 149
Supportive validation
- Submitted by
- per
- Main image
- Experimental details
- Immunohistochemical staining of human tonsil shows strong cytoplasmic positivity in reaction center cells.
- Validation comment
- Staining pattern partly consistent with experimental and/or bioinformatic data.
