Antibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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Validation data
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- Product number
- PAB18211 - Provider product page
- Provider
- Abnova Corporation
- Proper citation
- Abnova Corporation Cat#PAB18211, RRID:AB_10715743
- Product name
- PLCG2 polyclonal antibody
- Antibody type
- Polyclonal
- Description
- Rabbit polyclonal antibody raised against synthetic peptide of PLCG2.
- Storage
- Store at -20°C.Aliquot to avoid repeated freezing and thawing.
Submitted references Phospholipase C-gamma2 is essential for NK cell cytotoxicity and innate immunity to malignant and virally infected cells.
Mechanism of B-cell receptor-induced phosphorylation and activation of phospholipase C-gamma2.
The receptor tyrosine kinase MerTK activates phospholipase C gamma2 during recognition of apoptotic thymocytes by murine macrophages.
Caraux A, Kim N, Bell SE, Zompi S, Ranson T, Lesjean-Pottier S, Garcia-Ojeda ME, Turner M, Colucci F
Blood 2006 Feb 1;107(3):994-1002
Blood 2006 Feb 1;107(3):994-1002
Mechanism of B-cell receptor-induced phosphorylation and activation of phospholipase C-gamma2.
Kim YJ, Sekiya F, Poulin B, Bae YS, Rhee SG
Molecular and cellular biology 2004 Nov;24(22):9986-99
Molecular and cellular biology 2004 Nov;24(22):9986-99
The receptor tyrosine kinase MerTK activates phospholipase C gamma2 during recognition of apoptotic thymocytes by murine macrophages.
Todt JC, Hu B, Curtis JL
Journal of leukocyte biology 2004 Apr;75(4):705-13
Journal of leukocyte biology 2004 Apr;75(4):705-13
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Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Western blot analysis of extracts from Raw 264.7 cells, treated with PMA (125 ng/mL, 30 mins), using PLCG2 polyclonal antibody (Cat # PAB18211).Peptide "+" means "peptide blocking".
Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Immunohistochemical analysis of paraffin-embedded human brain tissue using PLCG2 polyclonal antibody (Cat # PAB18211).Peptide "+" means "peptide blocking".
- Validation comment
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)