Antibody data
- Antibody Data
- Antigen structure
- References [2]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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Validation data
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- Product number
- NB300-555 - Provider product page
- Provider
- Novus Biologicals
- Proper citation
- Novus Cat#NB300-555, RRID:AB_10002536
- Product name
- Mouse Monoclonal TRAP1 Antibody
- Antibody type
- Monoclonal
- Description
- Immunogen affinity purified. Detects tumor necrosis factor receptor-associated protein (TRAP1) from human tissues.
- Reactivity
- Human, Mouse
- Host
- Mouse
- Isotype
- IgG
- Vial size
- 100ug
- Concentration
- 1 mg/ml
- Storage
- Store at -20C. Avoid freeze-thaw cycles.
Submitted references Bax/Bak-dependent, Drp1-independent Targeting of X-linked Inhibitor of Apoptosis Protein (XIAP) into Inner Mitochondrial Compartments Counteracts Smac/DIABLO-dependent Effector Caspase Activation.
Intramitochondrial recruitment of endolysosomes mediates Smac degradation and constitutes a novel intrinsic apoptosis antagonizing function of XIAP E3 ligase.
Hamacher-Brady A, Brady NR
The Journal of biological chemistry 2015 Sep 4;290(36):22005-18
The Journal of biological chemistry 2015 Sep 4;290(36):22005-18
Intramitochondrial recruitment of endolysosomes mediates Smac degradation and constitutes a novel intrinsic apoptosis antagonizing function of XIAP E3 ligase.
Hamacher-Brady A, Choe SC, Krijnse-Locker J, Brady NR
Cell death and differentiation 2014 Dec;21(12):1862-76
Cell death and differentiation 2014 Dec;21(12):1862-76
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: TRAP1 Antibody (TRAP1-6) [NB300-555] - Figure 2 illustrates IP of TRAP1 visualized by Coomassie Blue staining.
Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: TRAP1 Antibody (TRAP1-6) [NB300-555] - Normal biopsies of deparaffinized Human liver tissue, dilution of 1:20.