BS6031

antibody from Bioworld Technology, Inc
Targeting: STAT5B
Provider product page for BS6031
Western blot
Immunocytochemistry
Immunohistochemistry

Antibody data

Product number
BS6031 - Provider product page
Provider
Bioworld Technology, Inc
Product name
Stat5b polyclonal antibody
Antibody type
Polyclonal
Antigen
Recombinant full length Human Stat5b.
Description
Stat5a and Stat5b (signal transducer and activator of transcription 5a and 5b; 96% homology) undergo receptor tyrosine kinase or G protein-coupled receptor-dependent phosphorylation in response to cytokines or growth factors, and then form homo- or heterodimers that translocate to the nucleus where they initiate transcription. Activation of Stat5b via IL-2, IL-4, CSF1 and growth hormones influences TCR signaling, apoptosis, adult mammary gland development and sexual dimorphism of liver gene expression. Stat5b is the major liver-expressed Stat5 form that has been shown to fuse with retinoic acid receptor-Ï« gene in acute promyelocytic leukemias (APLL).
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
STAT5B protein structure - BS6031 shown in red.