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Western blot
ImmunocytochemistryAntibody data
- Antibody Data
- Antigen structure
- References [11]
- Comments [0]
- Validations
- Immunocytochemistry [1]
- Immunohistochemistry [1]
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- Product number
- ABIN152872 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-alpha Adaptin antibody
- Antibody type
- Monoclonal
- Description
- Protein A purified
- Reactivity
- Human, Mouse, Rat, Bovine, Chicken/Avian, Porcine, Simian
- Host
- Mouse
- Isotype
- IgG
- Antibody clone number
- AC1-M11
- Vial size
- 0.5 mL
- Storage
- Store at -20°C. Avoid freeze-thaw cycles.
- Handling
- Avoid freeze-thaw cycles
Submitted references Calpain hydrolysis of alpha- and beta2-adaptins decreases clathrin-dependent endocytosis and may promote neurodegeneration.
Generation of coated intermediates of clathrin-mediated endocytosis on protein-free liposomes.
Association and colocalization of Eps15 with adaptor protein-2 and clathrin.
Molecular mechanisms in synaptic vesicle endocytosis and recycling.
Interaction of Shc with adaptor protein adaptins.
The tyrosine kinase substrate eps15 is constitutively associated with the plasma membrane adaptor AP-2.
Expression and localization of alpha-adaptin isoforms.
Adaptor self-aggregation, adaptor-receptor recognition and binding of alpha-adaptin subunits to the plasma membrane contribute to recruitment of adaptor (AP2) components of clathrin-coated pits.
Interaction of activated EGF receptors with coated pit adaptins.
100-kD proteins of Golgi- and trans-Golgi network-associated coated vesicles have related but distinct membrane binding properties.
100-kD coated vesicle proteins: molecular heterogeneity and intracellular distribution studied with monoclonal antibodies.
Rudinskiy N, Grishchuk Y, Vaslin A, Puyal J, Delacourte A, Hirling H, Clarke PG, Luthi-Carter R
The Journal of biological chemistry 2009 May 1;284(18):12447-58
The Journal of biological chemistry 2009 May 1;284(18):12447-58
Generation of coated intermediates of clathrin-mediated endocytosis on protein-free liposomes.
Takei K, Haucke V, Slepnev V, Farsad K, Salazar M, Chen H, De Camilli P
Cell 1998 Jul 10;94(1):131-41
Cell 1998 Jul 10;94(1):131-41
Association and colocalization of Eps15 with adaptor protein-2 and clathrin.
van Delft S, Schumacher C, Hage W, Verkleij AJ, van Bergen en Henegouwen PM
The Journal of cell biology 1997 Feb 24;136(4):811-21
The Journal of cell biology 1997 Feb 24;136(4):811-21
Molecular mechanisms in synaptic vesicle endocytosis and recycling.
De Camilli P, Takei K
Neuron 1996 Mar;16(3):481-6
Neuron 1996 Mar;16(3):481-6
Interaction of Shc with adaptor protein adaptins.
Okabayashi Y, Sugimoto Y, Totty NF, Hsuan J, Kido Y, Sakaguchi K, Gout I, Waterfield MD, Kasuga M
The Journal of biological chemistry 1996 Mar 1;271(9):5265-9
The Journal of biological chemistry 1996 Mar 1;271(9):5265-9
The tyrosine kinase substrate eps15 is constitutively associated with the plasma membrane adaptor AP-2.
Benmerah A, Gagnon J, Bègue B, Mégarbané B, Dautry-Varsat A, Cerf-Bensussan N
The Journal of cell biology 1995 Dec;131(6 Pt 2):1831-8
The Journal of cell biology 1995 Dec;131(6 Pt 2):1831-8
Expression and localization of alpha-adaptin isoforms.
Ball CL, Hunt SP, Robinson MS
Journal of cell science 1995 Aug;108 ( Pt 8):2865-75
Journal of cell science 1995 Aug;108 ( Pt 8):2865-75
Adaptor self-aggregation, adaptor-receptor recognition and binding of alpha-adaptin subunits to the plasma membrane contribute to recruitment of adaptor (AP2) components of clathrin-coated pits.
Chang MP, Mallet WG, Mostov KE, Brodsky FM
The EMBO journal 1993 May;12(5):2169-80
The EMBO journal 1993 May;12(5):2169-80
Interaction of activated EGF receptors with coated pit adaptins.
Sorkin A, Carpenter G
Science (New York, N.Y.) 1993 Jul 30;261(5121):612-5
Science (New York, N.Y.) 1993 Jul 30;261(5121):612-5
100-kD proteins of Golgi- and trans-Golgi network-associated coated vesicles have related but distinct membrane binding properties.
Wong DH, Brodsky FM
The Journal of cell biology 1992 Jun;117(6):1171-9
The Journal of cell biology 1992 Jun;117(6):1171-9
100-kD coated vesicle proteins: molecular heterogeneity and intracellular distribution studied with monoclonal antibodies.
Robinson MS
The Journal of cell biology 1987 Apr;104(4):887-95
The Journal of cell biology 1987 Apr;104(4):887-95
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Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- Figure 1 shows immunolocalization of alpha-adaptin in NRK cells using ABIN152872.
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- IHC
