Antibody data
- Antibody Data
- Antigen structure
- References [10]
- Comments [0]
- Validations
- Immunohistochemistry [1]
- Flow cytometry [2]
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Validation data
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- Product number
- NBP2-25208 - Provider product page
- Provider
- Novus Biologicals
- Product name
- Mouse Monoclonal B7-2/CD86 Antibody
- Antibody type
- Monoclonal
- Description
- Protein A or G purified. Recognizes a protein of 70kDa, which is identified as CD86 (HLDA V
- Reactivity
- Human, Mouse, Rat
- Host
- Mouse
- Isotype
- IgG
- Vial size
- 0.1 mg
- Concentration
- 0.2 mg/ml
- Storage
- Store at 4C.
Submitted references Active immunization with tau epitope in a mouse model of tauopathy induced strong antibody response together with improvement in short memory and pSer396-tau pathology.
HDAC8 inhibitor attenuates airway responses to antigen stimulus through synchronously suppressing galectin-3 expression and reducing macrophage-2 polarization.
The Possible Protective Role of Barley Seeds on the Spleen after Administration of Glucocorticoids in Adult Albino Rats: A Histological and Immunohistochemical Study.
M1 macrophages regulate TLR4/AP1 via paracrine to promote alveolar bone destruction in periodontitis.
Preventing the Solid Cancer Progression via Release of Anticancer-Cytokines in Co-Culture with Cold Plasma-Stimulated Macrophages.
TSLP promote M2 macrophages polarization and cardiac healing after myocardial infarction.
Ginsenoside Rg3 Mitigates Atherosclerosis Progression in Diabetic apoE-/- Mice by Skewing Macrophages to the M2 Phenotype.
Anti-tumor macrophages activated by ferumoxytol combined or surface-functionalized with the TLR3 agonist poly (I : C) promote melanoma regression.
Specific expression pattern of tissue cytokines analyzed through the Surface Acoustic Wave technique is associated with age-related spontaneous benign prostatic hyperplasia in rats.
Human Placental Hofbauer Cells Maintain an Anti-inflammatory M2 Phenotype despite the Presence of Gestational Diabetes Mellitus.
Joly-Amado A, Davtyan H, Serraneau K, Jules P, Zitnyar A, Pressman E, Zagorski K, Antonyan T, Hovakimyan A, Paek HJ, Gordon MN, Cribbs DH, Petrovsky N, Agadjanyan MG, Ghochikyan A, Morgan D
Neurobiology of disease 2020 Feb;134:104636
Neurobiology of disease 2020 Feb;134:104636
HDAC8 inhibitor attenuates airway responses to antigen stimulus through synchronously suppressing galectin-3 expression and reducing macrophage-2 polarization.
Li ML, Su XM, Ren Y, Zhao X, Kong LF, Kang J
Respiratory research 2020 Feb 28;21(1):62
Respiratory research 2020 Feb 28;21(1):62
The Possible Protective Role of Barley Seeds on the Spleen after Administration of Glucocorticoids in Adult Albino Rats: A Histological and Immunohistochemical Study.
Shehata MM, Saad Eldien HM, Meligy FY, Bahaidarh SY
Journal of microscopy and ultrastructure 2019 Oct-Dec;7(4):171-180
Journal of microscopy and ultrastructure 2019 Oct-Dec;7(4):171-180
M1 macrophages regulate TLR4/AP1 via paracrine to promote alveolar bone destruction in periodontitis.
Zhu LF, Li L, Wang XQ, Pan L, Mei YM, Fu YW, Xu Y
Oral diseases 2019 Nov;25(8):1972-1982
Oral diseases 2019 Nov;25(8):1972-1982
Preventing the Solid Cancer Progression via Release of Anticancer-Cytokines in Co-Culture with Cold Plasma-Stimulated Macrophages.
Kaushik NK, Kaushik N, Adhikari M, Ghimire B, Linh NN, Mishra YK, Lee SJ, Choi EH
Cancers 2019 Jun 18;11(6)
Cancers 2019 Jun 18;11(6)
TSLP promote M2 macrophages polarization and cardiac healing after myocardial infarction.
Liu D, Guo M, Zhou P, Xiao J, Ji X
Biochemical and biophysical research communications 2019 Aug 20;516(2):437-444
Biochemical and biophysical research communications 2019 Aug 20;516(2):437-444
Ginsenoside Rg3 Mitigates Atherosclerosis Progression in Diabetic apoE-/- Mice by Skewing Macrophages to the M2 Phenotype.
Guo M, Xiao J, Sheng X, Zhang X, Tie Y, Wang L, Zhao L, Ji X
Frontiers in pharmacology 2018;9:464
Frontiers in pharmacology 2018;9:464
Anti-tumor macrophages activated by ferumoxytol combined or surface-functionalized with the TLR3 agonist poly (I : C) promote melanoma regression.
Zhao J, Zhang Z, Xue Y, Wang G, Cheng Y, Pan Y, Zhao S, Hou Y
Theranostics 2018;8(22):6307-6321
Theranostics 2018;8(22):6307-6321
Specific expression pattern of tissue cytokines analyzed through the Surface Acoustic Wave technique is associated with age-related spontaneous benign prostatic hyperplasia in rats.
Rivera Del Alamo MM, Díaz-Lobo M, Busquets S, Rodríguez-Gil JE, Fernández-Novell JM
Biochemistry and biophysics reports 2018 Jul;14:26-34
Biochemistry and biophysics reports 2018 Jul;14:26-34
Human Placental Hofbauer Cells Maintain an Anti-inflammatory M2 Phenotype despite the Presence of Gestational Diabetes Mellitus.
Schliefsteiner C, Peinhaupt M, Kopp S, Lögl J, Lang-Olip I, Hiden U, Heinemann A, Desoye G, Wadsack C
Frontiers in immunology 2017;8:888
Frontiers in immunology 2017;8:888
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: B7-2/CD86 Antibody (BU63) [NBP2-25208] - Formalin-fixed, paraffin-embedded esophagus tumor tissue stained with CD86 antibody (5 ug/ml), peroxidase-conjugate and DAB chromogen. Note strong staining of differentiated squamous cells. TMA was used for this test.
Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Flow Cytometry: B7-2/CD86 Antibody (BU63) [NBP2-25208] - Flow Cytometric Analysis of PFA-fixed Ramos cells. B7-2/CD86 Antibody (BU63) followed by goat anti-Mouse IgG-CF488 (Blue); Isotype Control (Red).
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Flow Cytometry: B7-2/CD86 Antibody (BU63) [NBP2-25208] - Flow Cytometric Analysis of human PBMCs using B7-2/CD86 Antibody (BU63); Goat anti-Mouse IgG-CF488 (red); Isotype Control (green).