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Immunocytochemistry
ImmunohistochemistryAntibody data
- Antibody Data
- Antigen structure
- References [11]
- Comments [0]
- Validations
- Immunohistochemistry [1]
- Flow cytometry [1]
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- Product number
- V2056 - Provider product page
- Provider
- NSJ Bioreagents
- Product name
- CD86 Antibody
- Antibody type
- Monoclonal
- Antigen
- ARH-77 (B-lymphoblastoid cell line) was used as the immunogen for this CD86 antibody.
- Description
- Protein G purified antibody
- Reactivity
- Human, Mouse
- Host
- Mouse
- Conjugate
- Unconjugated
- Antibody clone number
- BU63
- Vial size
- 20 µg, 100 µg (with sodium azide), 100 µg (without sodium azide), 7 ml (prediluted for IHC use, if applicable)
- Storage
- Store the CD86 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
Submitted references Tissue-resident memory T cells populate the human brain.
Size-dependent effects of gold nanoparticles uptake on maturation and antitumor functions of human dendritic cells in vitro.
CD80 and CD86 IgC domains are important for quaternary structure, receptor binding and co-signaling function.
Molecular factors in dendritic cell responses to adsorbed glycoconjugates.
Activation of peroxisome proliferator-activated receptor gamma leads to upregulation of ESE-3 expression in human monocyte-derived dendritic cells.
Assessment of belatacept-mediated costimulation blockade through evaluation of CD80/86-receptor saturation.
Expression of the costimulatory molecule CD86, but not CD80, in keratinocytes of normal cervical epithelium and human papillomavirus-16 positive low squamous intraepithelial lesions.
Insertion of host-derived costimulatory molecules CD80 (B7.1) and CD86 (B7.2) into human immunodeficiency virus type 1 affects the virus life cycle.
Expression and function of CD80 and CD86 costimulator molecules on synovial dendritic cells in chronic arthritis.
Activation of human peripheral blood dendritic cells induces the CD86 co-stimulatory molecule.
B70/B7-2 is identical to CD86 and is the major functional ligand for CD28 expressed on human dendritic cells.
Smolders J, Heutinck KM, Fransen NL, Remmerswaal EBM, Hombrink P, Ten Berge IJM, van Lier RAW, Huitinga I, Hamann J
Nature communications 2018 Nov 2;9(1):4593
Nature communications 2018 Nov 2;9(1):4593
Size-dependent effects of gold nanoparticles uptake on maturation and antitumor functions of human dendritic cells in vitro.
Tomić S, Ðokić J, Vasilijić S, Ogrinc N, Rudolf R, Pelicon P, Vučević D, Milosavljević P, Janković S, Anžel I, Rajković J, Rupnik MS, Friedrich B, Colić M
PloS one 2014;9(5):e96584
PloS one 2014;9(5):e96584
CD80 and CD86 IgC domains are important for quaternary structure, receptor binding and co-signaling function.
Girard T, Gaucher D, El-Far M, Breton G, Sékaly RP
Immunology letters 2014 Sep;161(1):65-75
Immunology letters 2014 Sep;161(1):65-75
Molecular factors in dendritic cell responses to adsorbed glycoconjugates.
Hotaling NA, Cummings RD, Ratner DM, Babensee JE
Biomaterials 2014 Jul;35(22):5862-74
Biomaterials 2014 Jul;35(22):5862-74
Activation of peroxisome proliferator-activated receptor gamma leads to upregulation of ESE-3 expression in human monocyte-derived dendritic cells.
Sprater F, Azeem W, Appel S
Scandinavian journal of immunology 2014 Jan;79(1):20-6
Scandinavian journal of immunology 2014 Jan;79(1):20-6
Assessment of belatacept-mediated costimulation blockade through evaluation of CD80/86-receptor saturation.
Latek R, Fleener C, Lamian V, Kulbokas E 3rd, Davis PM, Suchard SJ, Curran M, Vincenti F, Townsend R
Transplantation 2009 Mar 27;87(6):926-33
Transplantation 2009 Mar 27;87(6):926-33
Expression of the costimulatory molecule CD86, but not CD80, in keratinocytes of normal cervical epithelium and human papillomavirus-16 positive low squamous intraepithelial lesions.
Ortiz-Sánchez E, Chávez-Olmos P, Piña-Sánchez P, Salcedo M, Garrido E
International journal of gynecological cancer : official journal of the International Gynecological Cancer Society 2007 May-Jun;17(3):571-80
International journal of gynecological cancer : official journal of the International Gynecological Cancer Society 2007 May-Jun;17(3):571-80
Insertion of host-derived costimulatory molecules CD80 (B7.1) and CD86 (B7.2) into human immunodeficiency virus type 1 affects the virus life cycle.
Giguère JF, Bounou S, Paquette JS, Madrenas J, Tremblay MJ
Journal of virology 2004 Jun;78(12):6222-32
Journal of virology 2004 Jun;78(12):6222-32
Expression and function of CD80 and CD86 costimulator molecules on synovial dendritic cells in chronic arthritis.
Summers KL, O'Donnell JL, Williams LA, Hart DN
Arthritis and rheumatism 1996 Aug;39(8):1287-91
Arthritis and rheumatism 1996 Aug;39(8):1287-91
Activation of human peripheral blood dendritic cells induces the CD86 co-stimulatory molecule.
McLellan AD, Starling GC, Williams LA, Hock BD, Hart DN
European journal of immunology 1995 Jul;25(7):2064-8
European journal of immunology 1995 Jul;25(7):2064-8
B70/B7-2 is identical to CD86 and is the major functional ligand for CD28 expressed on human dendritic cells.
Caux C, Vanbervliet B, Massacrier C, Azuma M, Okumura K, Lanier LL, Banchereau J
The Journal of experimental medicine 1994 Nov 1;180(5):1841-7
The Journal of experimental medicine 1994 Nov 1;180(5):1841-7
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Supportive validation
- Submitted by
- NSJ Bioreagents (provider)
- Main image
- Experimental details
- IHC testing of human esophageal tumor stained with CD86 antibody (BU63).
Supportive validation
- Submitted by
- NSJ Bioreagents (provider)
- Main image
- Experimental details
- FACS staining of human PBMCs using CD86 antibody (BU63).
