Antibody data
- Antibody Data
- Antigen structure
- References [4]
- Comments [0]
- Validations
- Flow cytometry [1]
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- Product number
- MAB5112 - Provider product page
- Provider
- Abnova Corporation
- Proper citation
- Abnova Corporation Cat#MAB5112, RRID:AB_10629831
- Product name
- CD86 monoclonal antibody, clone BU63 (PerCP)
- Antibody type
- Monoclonal
- Description
- Mouse monoclonal antibody raised against native CD86.
- Conjugate
- Red dye
- Isotype
- IgG
- Antibody clone number
- BU63
- Storage
- Store in the dark at 4°C. Do not freeze.Avoid prolonged exposure to light.Aliquot to avoid repeated freezing and thawing.
Submitted references Insertion of host-derived costimulatory molecules CD80 (B7.1) and CD86 (B7.2) into human immunodeficiency virus type 1 affects the virus life cycle.
Antigen-presenting T cells induce the development of cytotoxic CD4+ T cells. I. Involvement of the CD80-CD28 adhesion molecules.
The B7-2 (B70) costimulatory molecule expressed by monocytes and activated B lymphocytes is the CD86 differentiation antigen.
B70/B7-2 is identical to CD86 and is the major functional ligand for CD28 expressed on human dendritic cells.
Giguère JF, Bounou S, Paquette JS, Madrenas J, Tremblay MJ
Journal of virology 2004 Jun;78(12):6222-32
Journal of virology 2004 Jun;78(12):6222-32
Antigen-presenting T cells induce the development of cytotoxic CD4+ T cells. I. Involvement of the CD80-CD28 adhesion molecules.
Mauri D, Wyss-Coray T, Gallati H, Pichler WJ
Journal of immunology (Baltimore, Md. : 1950) 1995 Jul 1;155(1):118-27
Journal of immunology (Baltimore, Md. : 1950) 1995 Jul 1;155(1):118-27
The B7-2 (B70) costimulatory molecule expressed by monocytes and activated B lymphocytes is the CD86 differentiation antigen.
Engel P, Gribben JG, Freeman GJ, Zhou LJ, Nozawa Y, Abe M, Nadler LM, Wakasa H, Tedder TF
Blood 1994 Sep 1;84(5):1402-7
Blood 1994 Sep 1;84(5):1402-7
B70/B7-2 is identical to CD86 and is the major functional ligand for CD28 expressed on human dendritic cells.
Caux C, Vanbervliet B, Massacrier C, Azuma M, Okumura K, Lanier LL, Banchereau J
The Journal of experimental medicine 1994 Nov 1;180(5):1841-7
The Journal of experimental medicine 1994 Nov 1;180(5):1841-7
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Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Surface staining of human peripheral blood cells with CD86 monoclonal antibody, clone BU63 (PerCP) (Cat # MAB5112).
- Validation comment
- Flow Cytometry