CABT-B9383

antibody from Creative Diagnostics

Targeting: BAP1 hucep-6, KIAA0272, UCHL2

Western blot (Recommended by provider)

Flow cytometry (Recommended by provider)

Antibody Data

Product number

CABT-B9383

Provider

Creative Diagnostics

Product name

Mouse anti-Human BAP1 monoclonal antibody, clone 2H9

Antibody type

Monoclonal

Description

This gene belongs to the ubiquitin C-terminal hydrolase subfamily of deubiquitinating enzymes that are involved in the removal of ubiquitin from proteins. The encoded enzyme binds to the breast cancer type 1 susceptibility protein (BRCA1) via the RING finger domain of the latter and acts as a tumor suppressor. In addition, the enzyme may be involved in regulation of transcription, regulation of cell cycle and growth, response to DNA damage and chromatin dynamics. Germline mutations in this gene may be associated with tumor predisposition syndrome (TPDS), which involves increased risk of cancers including malignant mesothelioma, uveal melanoma and cutaneous melanoma. [provided by RefSeq, May 2013]

Reactivity

Human

Host

Mouse

Conjugate

Unconjugated

Isotype

IgG