Antibody data
- Antibody Data
- Antigen structure
- References [4]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
- Flow cytometry [1]
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- Product number
- ABIN951896 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-DNA Fragmentation Factor, 40kDa, beta Polypeptide (Caspase-Activated DNase) (DFFB) (AA 1-30), (N-Term) antibody
- Antibody type
- Polyclonal
- Description
- Affinity Chromatography on Protein A
- Reactivity
- Human
- Host
- Rabbit
- Epitope
- AA 1-30, N-Term
- Vial size
- 0.4 mL
- Storage
- Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
- Handling
- Avoid repeated freezing and thawing.
Submitted references High mobility group proteins stimulate DNA cleavage by apoptotic endonuclease DFF40/CAD due to HMG-box interactions with DNA.
The major apoptotic endonuclease DFF40/CAD is a deoxyribose-specific and double-strand-specific enzyme.
The chromatin of differentiating erythroblasts is cleaved into large size fragments independent of caspase activated DNase and apoptosis inducing factor.
Sequence elements in both subunits of the DNA fragmentation factor are essential for its nuclear transport.
Kalinowska-Herok M, Widłak P
Acta biochimica Polonica 2008;55(1):21-6
Acta biochimica Polonica 2008;55(1):21-6
The major apoptotic endonuclease DFF40/CAD is a deoxyribose-specific and double-strand-specific enzyme.
Hanus J, Kalinowska-Herok M, Widlak P
Apoptosis : an international journal on programmed cell death 2008 Mar;13(3):377-82
Apoptosis : an international journal on programmed cell death 2008 Mar;13(3):377-82
The chromatin of differentiating erythroblasts is cleaved into large size fragments independent of caspase activated DNase and apoptosis inducing factor.
Hristoskova S, Holzgreve W, Hahn S, Rusterholz C
Journal of cellular physiology 2007 Nov;213(2):490-4
Journal of cellular physiology 2007 Nov;213(2):490-4
Sequence elements in both subunits of the DNA fragmentation factor are essential for its nuclear transport.
Neimanis S, Albig W, Doenecke D, Kahle J
The Journal of biological chemistry 2007 Dec 7;282(49):35821-30
The Journal of biological chemistry 2007 Dec 7;282(49):35821-30
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Supportive validation
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- Experimental details
- WB
Supportive validation
- Submitted by
- antibodies-online (provider)
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- Experimental details
- IHC
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- FACS