Antibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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Validation data
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- Product number
- PAB3445 - Provider product page
- Provider
- Abnova Corporation
- Proper citation
- Abnova Corporation Cat#PAB3445, RRID:AB_1579916
- Product name
- YES1 polyclonal antibody
- Antibody type
- Polyclonal
- Description
- Rabbit polyclonal antibody raised against synthetic peptide of YES1.
- Storage
- Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.
Submitted references QM, a putative tumor suppressor, regulates proto-oncogene c-yes.
Regulation of the human sperm tyrosine kinase c-yes. Activation by cyclic adenosine 3',5'-monophosphate and inhibition by Ca(2+).
Chromosomal reassignment: YACs containing both YES1 and thymidylate synthase map to the short arm of chromosome 18.
Oh HS, Kwon H, Sun SK, Yang CH
The Journal of biological chemistry 2002 Sep 27;277(39):36489-98
The Journal of biological chemistry 2002 Sep 27;277(39):36489-98
Regulation of the human sperm tyrosine kinase c-yes. Activation by cyclic adenosine 3',5'-monophosphate and inhibition by Ca(2+).
Leclerc P, Goupil S
Biology of reproduction 2002 Jul;67(1):301-7
Biology of reproduction 2002 Jul;67(1):301-7
Chromosomal reassignment: YACs containing both YES1 and thymidylate synthase map to the short arm of chromosome 18.
Silverman GA, Kuo WL, Taillon-Miller P, Gray JW
Genomics 1993 Feb;15(2):442-5
Genomics 1993 Feb;15(2):442-5
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Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Western blot analysis of YES1 polyclonal antibody (Cat # PAB3445) in mouse kidney tissue lysate. YES1 (arrow) was detected using purified polyclonal antibody. Secondary HRP-anti-rabbit was used for signal visualization with chemiluminescence.
Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Formalin-fixed and paraffin-embedded human cancer tissue reacted with YES1 polyclonal antibody (Cat # PAB3445) , which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry ; clinical relevance has not been evaluated. BC = breast carcinoma.
- Validation comment
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)