CABT-B1850

antibody from Creative Diagnostics

Targeting: DIDO1 BYE1, C20orf158, DATF1, DIO-1, DIO1, dJ885L7.8, FLJ11265, KIAA0333

Western blot (Recommended by provider)

Immunocytochemistry (Recommended by provider)

Antibody Data

Product number

CABT-B1850

Provider

Creative Diagnostics

Product name

Anti-Dido3 polyclonal antibody

Antibody type

Polyclonal

Description

Death inducer obliterator 3 (Dido3) is a transcription factor encoded by the DIDO1 (also known as BYE1, DIO1, DATF1, DIDO2, DIDO3) gene in human. Three other isoforms, including Dido1 & 2 (isoform 2 & 1, respectively), are also encoded by the same gene through alternative splicing. In addition to early research activities regarding apoptosis-inducing activity of Dido proteins, later studies reveal important roles of Dido1 & Dido3 (isoform 4) in maintaining stem cell genomic stability and self-renewal. Dido3 binds histone H3K4me3 in the nucleus. Histone H3T3 or H3T6 phosphorylation causes H3K4 demethylation and Dido3 translocation from chromatin to the mitotic spindle.

Reactivity

Human

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Vial size

100 _g

Concentration

Please refer to lot specific datasheet.

Storage

Stable for 1 year at 2-8°C from date of receipt.