Antibody data
- Antibody Data
- Antigen structure
- References [1]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
- Other assay [1]
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Validation data
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- Product number
- PA5-37698 - Provider product page
- Provider
- Invitrogen Antibodies
- Product name
- Phospho-JNK1 (Thr183) Polyclonal Antibody
- Antibody type
- Polyclonal
- Antigen
- Synthetic peptide
- Description
- A suggested positive control for Western blot is 293 cells; suggested positive control for IHC is human breast carcinoma.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 100 µL
- Concentration
- 1 mg/mL
- Storage
- -20°C
Submitted references NLRP3 inflammasome via IL-1β regulates PCSK9 secretion.
Ding Z, Wang X, Liu S, Zhou S, Kore RA, Mu S, Deng X, Fan Y, Mehta JL
Theranostics 2020;10(16):7100-7110
Theranostics 2020;10(16):7100-7110
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Supportive validation
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Western blot analysis of extracts from 293 cells using SAPK/JNK (pThr183) polyclonal antibody (Product # PA5-37698) (Lane 2) and the same antibody preincubated with blocking peptide (Lane 1).
Supportive validation
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Immunohistochemical analysis of Phospho-JNK1 (Thr183) in paraffin-embedded Human breast carcinoma tissue using Phospho-JNK1 (Thr183) Polyclonal Antibody (Product # PA5-37698) (left) or the same antibody preincubated with blocking peptide (right).
Supportive validation
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Figure 3 MAPKs are involved in IL-1beta-induced PCSK9 secretion. ( A ) and ( B ) IL-1beta and PCSK9 secretion and MAPKs expression. ( C ) and ( D ) PCSK9 expression in WT mice, ERK -/- , JNK -/- and P38 -/- mice. ( E ) ELISA analysis for PCSK9 secretion in MPM culture medium. ****P