633101

antibody from BioLegend
Targeting: MAPK8 JNK, JNK1, PRKM8, SAPK1
Provider product page for 633101
Western blot
Immunocytochemistry
Immunoprecipitation

Antibody data

Product number
633101 - Provider product page
Provider
BioLegend
Proper citation
BioLegend Cat#633101, RRID:AB_2140575
Product name
Purified anti-JNK1
Antibody type
Polyclonal
Antigen
Peptide mapping to the carboxy terminus of human JNK1
Description
The MAPK family includes several subgroups encompassing the extracellular signal-regulated kinase (ERK) family, the p38 Map kinase family, and c-Jun NH2-terminal kinase (JNK) family. JNK kinase group includes 3 members, JNK1, JNK2, and JNK3. JNK kinases are phosphorylated in response to various activations by environmental stress and pro-inflammatory cytokines by phosphorylating a number of transcription factors, primarily components of AP-1 such as c-Jun and ATF2 and thus regulate AP-1 transcriptional activity. JNK kinases are characterized by requirement for dual phosphorylation at a T-P-Y motif for enzymatic activation. The Poly6331 antibody has been shown to be useful for western blotting, immunoprecipitation, and immunohistochemistry of human, mouse, and rat JNK1 p46 and JNK1 p54 protein.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Conjugate
Unconjugated
Vial size
125 µl
Storage
The antibody solution should be stored undiluted at 4°C. DO NOT FREEZE.
MAPK8 protein structure - 633101 shown in red.