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- Product number
- ABIN2840612 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Low Density Lipoprotein Receptor-Related Protein 6 (LRP6) (AA 1531-1560), (C-Term) antibody
- Antibody type
- Polyclonal
- Description
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
- Reactivity
- Human
- Host
- Rabbit
- Epitope
- AA 1531-1560, C-Term
- Antibody clone number
- RB01837
- Vial size
- 80 μL
- Storage
- Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Submitted references LRP6 protein regulates low density lipoprotein (LDL) receptor-mediated LDL uptake.
Wild-type LRP6 inhibits, whereas atherosclerosis-linked LRP6R611C increases PDGF-dependent vascular smooth muscle cell proliferation.
LRP6 overexpression defines a class of breast cancer subtype and is a target for therapy.
Isolation and characterization of LRP6, a novel member of the low density lipoprotein receptor gene family.
Ye ZJ, Go GW, Singh R, Liu W, Keramati AR, Mani A
The Journal of biological chemistry 2012 Jan 6;287(2):1335-44
The Journal of biological chemistry 2012 Jan 6;287(2):1335-44
Wild-type LRP6 inhibits, whereas atherosclerosis-linked LRP6R611C increases PDGF-dependent vascular smooth muscle cell proliferation.
Keramati AR, Singh R, Lin A, Faramarzi S, Ye ZJ, Mane S, Tellides G, Lifton RP, Mani A
Proceedings of the National Academy of Sciences of the United States of America 2011 Feb 1;108(5):1914-8
Proceedings of the National Academy of Sciences of the United States of America 2011 Feb 1;108(5):1914-8
LRP6 overexpression defines a class of breast cancer subtype and is a target for therapy.
Liu CC, Prior J, Piwnica-Worms D, Bu G
Proceedings of the National Academy of Sciences of the United States of America 2010 Mar 16;107(11):5136-41
Proceedings of the National Academy of Sciences of the United States of America 2010 Mar 16;107(11):5136-41
Isolation and characterization of LRP6, a novel member of the low density lipoprotein receptor gene family.
Brown SD, Twells RC, Hey PJ, Cox RD, Levy ER, Soderman AR, Metzker ML, Caskey CT, Todd JA, Hess JF
Biochemical and biophysical research communications 1998 Jul 30;248(3):879-88
Biochemical and biophysical research communications 1998 Jul 30;248(3):879-88
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Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- IHC
