abx032705

antibody from Abbexa

Targeting: LRP6 ADCAD2

Western blot (Recommended by provider)

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

abx032705

Provider

Abbexa

Product name

Low Density Lipoprotein Receptor Related Protein 6 (LRP6) Antibody

Antibody type

Polyclonal

Description

LRP6 is essential for the Wnt/beta catenin signaling pathway, probably by acting as a coreceptor together with Frizzled for Wnt. It is a specific, high-affinity receptor for DKK1 and DKK2, but not DKK3. The interaction with DKK1 blocks LRP6-mediated Wnt/beta catenin signaling via LRP6 removal via Kremen proteins-mediated endocytosis.

Reactivity

Human

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Vial size

80 µl

Concentration

1.2 mg/ml

Storage

Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.