BS7887

antibody from Bioworld Technology, Inc
Targeting: HELLS LSH, Nbla10143, PASG, SMARCA6
Provider product page for BS7887
Western blot
Immunocytochemistry
Immunoprecipitation
Immunohistochemistry
Chromatin Immunoprecipitation

Antibody data

Product number
BS7887 - Provider product page
Provider
Bioworld Technology, Inc
Product name
HELLS polyclonal antibody
Antibody type
Polyclonal
Antigen
Recombinant full length Human HELLS.
Description
The SNF2 family of helicases are thought to act as transcriptional regulators by their ability to alter the structure of chromatin. One such member, Lymphoid-Specific Helicase (Lsh, also designated Hells for lymphoid-specific DNA helicase), is highly expressed in lymphoid precursor cells in adult animals and is required for the proliferation of peripheral T lymphocytes. Lsh is also expressed in fetal liver and more abundantly in fetal thymus. Lsh protein shows substantial homology to other members of the SNF2 family that are involved in chromatin remodeling and transcription, however does not show similarity to members involved in DNA repair or recombination. The similarity of Lsh to another SNF2 homolog, Mi-2, which functions as a transcriptional silencer in chromatin remodeling, suggests that Lsh may participate in chromatin repression to regulate transcription, rather than chromatin ¡ùopening¡ì.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
HELLS protein structure - BS7887 shown in red.