Antibody data
- Antibody Data
- Antigen structure
- References [0]
- Comments [0]
- Validations
- Flow cytometry [1]
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Validation data
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- Product number
- 354514 - Provider product page
- Provider
- BioLegend
- Proper citation
- BioLegend Cat#354514, RRID:AB_2563872
- Product name
- Brilliant Violet 421™ anti-human CD304 (Neuropilin-1)
- Antibody type
- Monoclonal
- Antigen
- CD304-Fc Fusion protein
- Description
- CD304, also known as neuropilin-1, BDCA-4 and VEGF165R, is a 140 kD type I transmembrane protein. Its extracellular region contains 2 CUB, 2 FV/FVIII, and one MAM domain; a soluble isoform is produced by alternative mRNA splicing. CD304 is involved in angiogenesis, neural development, and tumor metastasis. It's expressed by plasmacytoid dendritic cells, thymocytes, neurons, endothelium, and a subset of TFH cells. CD304 is also expressed in several carcinomas, and a high expression of this molecule in prostate cancer correlates with a poor prognosis.
- Reactivity
- Human
- Host
- Mouse
- Conjugate
- Blue dye
- Antibody clone number
- 12C2
- Vial size
- 100 tests
- Storage
- 2°C-8°C
- Handling
- Ambient RT
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Supportive validation
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- BioLegend (provider)
- Main image
- Experimental details
- Human peripheral blood mononuclear cells were stained with CD303 APC and CD304 (clone 12C2) Brilliant Violet 421™ (top) or mouse IgG2a, κ Brilliant Violet 421™ isotype control (bottom). Data shown was gated on the lymphocyte populations.
- Conjugate
- Blue dye