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- References [16]
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- Product number
- 10252-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#10252-1-AP, RRID:AB_2229016
- Product name
- Cdc20 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated Cdc20 antibody (Cat. #10252-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: IHC, IP, WB,ELISA.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references CDC20 regulates the cell proliferation and radiosensitivity of P53 mutant HCC cells through the Bcl-2/Bax pathway.
The Oncogenic Role of APC/C Activator Protein Cdc20 by an Integrated Pan-Cancer Analysis in Human Tumors.
Comparison of the major cell populations among osteoarthritis, Kashin-Beck disease and healthy chondrocytes by single-cell RNA-seq analysis.
Identification of biomarkers for the transition from low-grade glioma to secondary glioblastoma by an integrated bioinformatic analysis.
Ursolic Acid Regulates Cell Cycle and Proliferation in Colon Adenocarcinoma by Suppressing Cyclin B1.
Downregulation of CDC20 Increases Radiosensitivity through Mcl-1/p-Chk1-Mediated DNA Damage and Apoptosis in Tumor Cells.
Ordered dephosphorylation initiated by the selective proteolysis of cyclin B drives mitotic exit.
Novel gene-specific translation mechanism of dysregulated, chronic inflammation reveals promising, multifaceted COVID-19 therapeutics.
Anaphase-promoting complex/cyclosome-Cdc-20 promotes Zwint-1 degradation.
CDC20 Knockdown and Acidic Microenvironment Collaboratively Promote Tumorigenesis through Inhibiting Autophagy and Apoptosis.
Spatiotemporal Proteomic Analysis of Stress Granule Disassembly Using APEX Reveals Regulation by SUMOylation and Links to ALS Pathogenesis.
Translation control of the immune checkpoint in cancer and its therapeutic targeting.
Upregulation of kinesin family member 4A enhanced cell proliferation via activation of Akt signaling and predicted a poor prognosis in hepatocellular carcinoma.
Plk1 bound to Bub1 contributes to spindle assembly checkpoint activity during mitosis.
Evaluation of the Antitumor Efficacy of RNAi-Mediated Inhibition of CDC20 and Heparanase in an Orthotopic Liver Tumor Model.
Probing the cell death signaling pathway of HepG2 cell line induced by copper-1,10-phenanthroline complex.
Zhao S, Zhang Y, Lu X, Ding H, Han B, Song X, Miao H, Cui X, Wei S, Liu W, Chen S, Wang J
International journal of biological sciences 2021;17(13):3608-3621
International journal of biological sciences 2021;17(13):3608-3621
The Oncogenic Role of APC/C Activator Protein Cdc20 by an Integrated Pan-Cancer Analysis in Human Tumors.
Wu F, Sun Y, Chen J, Li H, Yao K, Liu Y, Liu Q, Lu J
Frontiers in oncology 2021;11:721797
Frontiers in oncology 2021;11:721797
Comparison of the major cell populations among osteoarthritis, Kashin-Beck disease and healthy chondrocytes by single-cell RNA-seq analysis.
Wang X, Ning Y, Zhang P, Poulet B, Huang R, Gong Y, Hu M, Li C, Zhou R, Lammi MJ, Guo X
Cell death & disease 2021 May 27;12(6):551
Cell death & disease 2021 May 27;12(6):551
Identification of biomarkers for the transition from low-grade glioma to secondary glioblastoma by an integrated bioinformatic analysis.
Zhao L, Zhang J, Liu Z, Zhao P
American journal of translational research 2020;12(4):1222-1238
American journal of translational research 2020;12(4):1222-1238
Ursolic Acid Regulates Cell Cycle and Proliferation in Colon Adenocarcinoma by Suppressing Cyclin B1.
Yang M, Hu C, Cao Y, Liang W, Yang X, Xiao T
Frontiers in pharmacology 2020;11:622212
Frontiers in pharmacology 2020;11:622212
Downregulation of CDC20 Increases Radiosensitivity through Mcl-1/p-Chk1-Mediated DNA Damage and Apoptosis in Tumor Cells.
Gao Y, Wen P, Chen B, Hu G, Wu L, Xu A, Zhao G
International journal of molecular sciences 2020 Sep 12;21(18)
International journal of molecular sciences 2020 Sep 12;21(18)
Ordered dephosphorylation initiated by the selective proteolysis of cyclin B drives mitotic exit.
Holder J, Mohammed S, Barr FA
eLife 2020 Sep 1;9
eLife 2020 Sep 1;9
Novel gene-specific translation mechanism of dysregulated, chronic inflammation reveals promising, multifaceted COVID-19 therapeutics.
Wang L, Muneer A, Xie L, Zhang F, Wu B, Mei L, Lenarcic EM, Feng EH, Song J, Xiong Y, Yu X, Wang C, Gheorghe C, Torralba K, Cook JG, Wan YY, Moorman NJ, Song H, Jin J, Chen X
bioRxiv : the preprint server for biology 2020 Nov 16;
bioRxiv : the preprint server for biology 2020 Nov 16;
Anaphase-promoting complex/cyclosome-Cdc-20 promotes Zwint-1 degradation.
He Y, Li R, Gu L, Deng H, Zhao Y, Guo Y, Yu S, Wang G
Cell biochemistry and function 2020 Jun;38(4):451-459
Cell biochemistry and function 2020 Jun;38(4):451-459
CDC20 Knockdown and Acidic Microenvironment Collaboratively Promote Tumorigenesis through Inhibiting Autophagy and Apoptosis.
Gu Q, Li F, Ge S, Zhang F, Jia R, Fan X
Molecular therapy oncolytics 2020 Jun 26;17:94-106
Molecular therapy oncolytics 2020 Jun 26;17:94-106
Spatiotemporal Proteomic Analysis of Stress Granule Disassembly Using APEX Reveals Regulation by SUMOylation and Links to ALS Pathogenesis.
Marmor-Kollet H, Siany A, Kedersha N, Knafo N, Rivkin N, Danino YM, Moens TG, Olender T, Sheban D, Cohen N, Dadosh T, Addadi Y, Ravid R, Eitan C, Toth Cohen B, Hofmann S, Riggs CL, Advani VM, Higginbottom A, Cooper-Knock J, Hanna JH, Merbl Y, Van Den Bosch L, Anderson P, Ivanov P, Geiger T, Hornstein E
Molecular cell 2020 Dec 3;80(5):876-891.e6
Molecular cell 2020 Dec 3;80(5):876-891.e6
Translation control of the immune checkpoint in cancer and its therapeutic targeting.
Xu Y, Poggio M, Jin HY, Shi Z, Forester CM, Wang Y, Stumpf CR, Xue L, Devericks E, So L, Nguyen HG, Griselin A, Gordan JD, Umetsu SE, Reich SH, Worland ST, Asthana S, Barna M, Webster KR, Cunningham JT, Ruggero D
Nature medicine 2019 Feb;25(2):301-311
Nature medicine 2019 Feb;25(2):301-311
Upregulation of kinesin family member 4A enhanced cell proliferation via activation of Akt signaling and predicted a poor prognosis in hepatocellular carcinoma.
Huang Y, Wang H, Lian Y, Wu X, Zhou L, Wang J, Deng M, Huang Y
Cell death & disease 2018 Feb 2;9(2):141
Cell death & disease 2018 Feb 2;9(2):141
Plk1 bound to Bub1 contributes to spindle assembly checkpoint activity during mitosis.
Ikeda M, Tanaka K
Scientific reports 2017 Aug 18;7(1):8794
Scientific reports 2017 Aug 18;7(1):8794
Evaluation of the Antitumor Efficacy of RNAi-Mediated Inhibition of CDC20 and Heparanase in an Orthotopic Liver Tumor Model.
Liu M, Zhang Y, Liao Y, Chen Y, Pan Y, Tian H, Zhan Y, Liu D
Cancer biotherapy & radiopharmaceuticals 2015 Aug;30(6):233-9
Cancer biotherapy & radiopharmaceuticals 2015 Aug;30(6):233-9
Probing the cell death signaling pathway of HepG2 cell line induced by copper-1,10-phenanthroline complex.
Wu J, Chen W, Yin Y, Zheng Z, Zou G
Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine 2014 Jun;27(3):445-58
Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine 2014 Jun;27(3):445-58
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The Cdc20 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human Cdc20. This antibody recognizes human,mouse,rat antigen. The Cdc20 antibody has been validated for the following applications: ELISA, WB analysis.
