11-1017-25

antibody from ABEOMICS Inc.

Targeting: YWHAZ 14-3-3-zeta, KCIP-1, YWHAD

Western blot (Supportive data in Antibodypedia)

Antibody Data

Product number

11-1017-25

Provider

ABEOMICS Inc.

Product name

Anti-14-3-3 Zeta Antibody

Antibody type

Polyclonal

Description

14-3-3zeta is a central cellular hub protein regulating multiple signaling pathways involved in cancer development, progression and therapeutic resistance. It is linked to endoplasmic reticulum (ER) function in neurons, with reduced levels provoking ER stress and increasing vulnerability to excitotoxic injury. It is up-regulated in malignancy, which suggests its potential as a putative drug target for the treatment of colorectal cancer and tumorgenesis in pancreas,EOC (epithelial ovarian cancer).

Reactivity

Human

Host

Rabbit

Antigen sequence

A partial length recombinant 14-3-3
Zeta protein (amino acids 30-245)
was used as the immunogen for this
antibody.


Vial size

25 µg

Concentration

0.5 mg/ml

Storage

Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeat freezing and thawing

Western blot

Supportive validation

Submitted by

ABEOMICS Inc. (provider)

Main image

Experimental details

Western blot analysis of 14-3-3 Zeta. Anti-14-3-3 Zeta antibody (11-1017) was used at 2 µg/ml on (1) T98G and (2) U87 lysates.