BS6620

antibody from Bioworld Technology, Inc
Targeting: HCK JTK9
Provider product page for BS6620
Western blot
Immunohistochemistry

Antibody data

Product number
BS6620 - Provider product page
Provider
Bioworld Technology, Inc
Product name
HCK polyclonal antibody
Antibody type
Polyclonal
Antigen
Recombinant full length Human HCK.
Description
Src is the human homolog of the v-src gene of the Rous sarcoma virus, also called avian sarcoma virus or ASV. Src was the first proto-oncogenic non-receptor tyrosine kinase characterized in human. By virtue of common structural motifs, the Src family is composed of nine members in vertebrates, including Src, Yes, Fgr, Frk, Fyn, Lyn, Hck, Lck and Blk. Src-family kinases transduce signals that are involved in the control of a variety of cellular processes, including proliferation, differentiation, motility and adhesion. Src family kinases contain an amino terminal cell membrane anchor followed by an SH3 domain and an SH2 domain involved in modular association and activation, respectively. Src family kinases are normally maintained in an inactive state and can be activated transiently during cellular events such as mitosis. Different subcellular localizations of Src family kinases may be important for the regulation of specific cellular processes such as mitogenesis, cytoskeletal organization and membrane trafficking. The human hemopoietic cell kinase (Hck) gene maps to chromosome 20q11-q12 and encodes a 505 amino acid protein.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
HCK protein structure - BS6620 shown in red.