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Western blot
ELISAAntibody data
- Antibody Data
- Antigen structure
- References [4973]
- Comments [0]
- Validations
- Western blot [2]
- Immunocytochemistry [1]
- Immunoprecipitation [1]
- Immunohistochemistry [2]
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- Product number
- 60004-1-Ig - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#60004-1-Ig, RRID:AB_2107436
- Product name
- GAPDH antibody
- Antibody type
- Monoclonal
- Description
- GAPDH antibody (Cat. #60004-1-Ig) is a mouse monoclonal antibody that shows reactivity with human, mouse, rat, yeast, plant, zebrafish and has been validated for the following applications: FC, IF, IP, WB, ELISA.
- Reactivity
- Human, Mouse, Rat, Yeast, Zebrafish
- Host
- Mouse
- Conjugate
- Unconjugated
- Isotype
- IgG
- Antibody clone number
- 1E6D9
- Vial size
- 150ul
Submitted references Injectable self-healing hydrogel with siRNA delivery property for sustained STING silencing and enhanced therapy of intervertebral disc degeneration.
Isoxanthohumol, a component of Sophora flavescens, promotes the activation of the NLRP3 inflammasome and induces idiosyncratic hepatotoxicity.
H. pylori CagA activates the NLRP3 inflammasome to promote gastric cancer cell migration and invasion.
Increased m6A-RNA methylation and FTO suppression is associated with myocardial inflammation and dysfunction during endotoxemia in mice.
PPARα agonist fenofibrate relieves acquired resistance to gefitinib in non-small cell lung cancer by promoting apoptosis via PPARα/AMPK/AKT/FoxO1 pathway.
CircRNA_01477 influences axonal growth via regulating miR-3075/FosB/Stat3 axis.
Selective activation of cannabinoid receptor-2 reduces white matter injury via PERK signaling in a rat model of traumatic brain injury.
Inhibition of progesterone receptor membrane component-1 exacerbates neonatal hypoxic-ischemic cerebral damage in male mice.
Novel mutations of TYK2 leading to divergent clinical phenotypes.
Glycocalyx is critical for blood-brain barrier integrity by suppressing caveolin1-dependent endothelial transcytosis following ischemic stroke.
Morphological changes of macrophages and their potential contribution to tendon healing.
Is platelet responsiveness to clopidogrel attenuated in overweight or obese patients and why? A reverse translational study in mice.
Silencing TXNIP ameliorates high uric acid-induced insulin resistance via the IRS2/AKT and Nrf2/HO-1 pathways in macrophages.
Ghrelin alleviates 6-hydroxydopamine-induced neurotoxicity in SH-SY5Y cells.
3-(3-Hydroxyphenyl)propionic acid, a microbial metabolite of quercetin, inhibits monocyte binding to endothelial cells via modulating E-selectin expression.
MACF1 promotes osteoblastic cell migration by regulating MAP1B through the GSK3beta/TCF7 pathway.
Synthesis compound XCR-7a ameliorates LPS-induced inflammatory response by inhibiting the phosphorylation of c-Fos.
CAMKK2 Defines Ferroptosis Sensitivity of Melanoma Cells by Regulating AMPK‒NRF2 Pathway.
Luteolin alleviates ischemia/reperfusion injury-induced no-reflow by regulating Wnt/β-catenin signaling in rats.
Impaired vessel relaxation response and increased infarct size in smooth muscle cannabinoid receptor 1 knockout mice.
Minimally modified low-density lipoprotein upregulates mouse mesenteric arterial 5-HT1B receptor in vivo via activation of the JAK2/STAT3 pathway.
Overexpression of DOCK6 in oral squamous cell cancer promotes cellular migration and invasion and is associated with poor prognosis.
β-Hydroxybutyrate impairs neutrophil migration distance through activation of a protein kinase C and myosin light chain 2 signaling pathway in ketotic cows.
Bioglass promotes wound healing by inhibiting endothelial cell pyroptosis through regulation of the connexin 43/reactive oxygen species (ROS) signaling pathway.
Cisplatin induces damage of auditory cells: Possible relation with dynamic variation in calcium homeostasis and responding channels.
Protective role of m6A binding protein YTHDC2 on CCNB2 in manganese-induced spermatogenesis dysfunction.
Immunomodulatory Effect of Serum Exosomes From Crohn Disease on Macrophages via Let-7b-5p/TLR4 Signaling.
Enteromorpha prolifera polysaccharide-zinc complex modulates the immune response and alleviates LPS-induced intestinal inflammation via inhibiting the TLR4/NF-κB signaling pathway.
Neuroprotective Effects of Rhodiola Sacra on Transient Global Cerebral Ischemia Through Activating AMPK/Nrf2 Pathway in Rats.
Renoprotective activity of Ribes diacanthum pall (RDP) against inflammation in cisplatin-stimulated mice model and human renal tubular epithelial cells.
Protective effect of oligosaccharides isolated from Panax ginseng C. A. Meyer against UVB-induced skin barrier damage in BALB/c hairless mice and human keratinocytes.
CHMP2B regulates TDP-43 phosphorylation and cytotoxicity independent of autophagy via CK1.
LncRNA SNHG16 accelerates atherosclerosis and promotes ox-LDL-induced VSMC growth via the miRNA-22-3p/HMGB2 axis.
Salidroside alleviates oxidative stress and apoptosis via AMPK/Nrf2 pathway in DHT-induced human granulosa cell line KGN.
Iron overload inhibits cell proliferation and promotes autophagy via PARP1/SIRT1 signaling in endometriosis and adenomyosis.
BDE-47 induced PC-12 cell differentiation via TrkA downstream pathways and caused the loss of hippocampal neurons in BALB/c mice.
Anti-tumor effect of Yanggan Huayu granule by inducing AKT-mediated apoptosis in hepatocellular carcinoma.
Ajuba functions as a co-activator of C/EBPβ to induce expression of PPARγ and C/EBPα during adipogenesis.
Highly sensitive detection of multiple proteins from single cells by MoS2-FET biosensors.
Delayed inhibition of ERK and p38 attenuates neuropathic pain without affecting motor function recovery after peripheral nerve injury.
NMN recruits GSH to enhance GPX4-mediated ferroptosis defense in UV irradiation induced skin injury.
Docosahexaenoic acid reduces hypoglycemia-induced neuronal necroptosis via the peroxisome proliferator-activated receptor γ/nuclear factor-κB pathway.
The Impact of Long-term Physical Inactivity on Adipose Tissue Immunometabolism.
Dapagliflozin alleviates advanced glycation end product induced podocyte injury through AMPK/mTOR mediated autophagy pathway.
DHHC5 facilitates oligodendrocyte development by palmitoylating and activating STAT3.
Inhibition of gap junction communication between cells can induce apoptosis of corpus cavernosum smooth muscle in guinea pigs.
Tanshinone IIA inhibits gastric cancer cell stemness through inducing ferroptosis.
Neuroglobin expression and function in the temporal cortex of bilirubin encephalopathy rats.
Combination of the 6-thioguanine and disulfiram/Cu synergistically inhibits proliferation of triple-negative breast cancer cells by enhancing DNA damage and disrupting DNA damage checkpoint.
Dietary mulberry-leaf flavonoids improve the eggshell quality of aged breeder hens.
Pre-clinical study of human umbilical cord mesenchymal stem cell transplantation for the treatment of traumatic brain injury: safety evaluation from immunogenic and oncogenic perspectives.
LncRNA MT1DP promotes cadmium-induced DNA replication stress by inhibiting chromatin recruitment of SMARCAL1.
OGDHL ameliorates cognitive impairment and Alzheimer's disease-like pathology via activating Wnt/β-catenin signaling in Alzheimer's disease mice.
Anti-fatigue effect of hypericin in a chronic forced exercise mouse model.
A novel role for apatinib in enhancing radiosensitivity in non-small cell lung cancer cells by suppressing the AKT and ERK pathways.
Identification and validation of candidate genes dysregulated in alveolar macrophages of acute respiratory distress syndrome.
N-acetyl-L-tryptophan attenuates hepatic ischemia-reperfusion injury via regulating TLR4/NLRP3 signaling pathway in rats.
Involvement of plasminogen activator inhibitor-1 and its related molecules in atrial fibrosis in patients with atrial fibrillation.
Identification of potential genes in upper tract urothelial carcinoma using next-generation sequencing with bioinformatics and in vitro analyses.
Melatonin ameliorates myocardial injury by reducing apoptosis and autophagy of cardiomyocytes in a rat cardiopulmonary bypass model.
Long non-coding RNA taurine upregulated gene 1 is downregulated in osteoporosis and influences the osteogenic differentiation of bone marrow mesenchymal stem cells.
Screening and identification of endometrial proteins as novel potential biomarkers for repeated implantation failure.
Curdione and Schisandrin C Synergistically Reverse Hepatic Fibrosis via Modulating the TGF-β Pathway and Inhibiting Oxidative Stress.
Platelet-Derived Microvesicles Promote VSMC Dedifferentiation After Intimal Injury via Src/Lamtor1/mTORC1 Signaling.
An Advanced Systems Pharmacology Strategy Reveals AKR1B1, MMP2, PTGER3 as Key Genes in the Competing Endogenous RNA Network of Compound Kushen Injection Treating Gastric Carcinoma by Integrated Bioinformatics and Experimental Verification.
Reducing Inflammation and Vascular Invasion in Intervertebral Disc Degeneration via Cystathionine-γ-Lyase Inhibitory Effect on E-Selectin.
PBX1 Attenuates Hair Follicle-Derived Mesenchymal Stem Cell Senescence and Apoptosis by Alleviating Reactive Oxygen Species-Mediated DNA Damage Instead of Enhancing DNA Damage Repair.
Increased Nuclear Transporter Importin 7 Contributes to the Tumor Growth and Correlates With CD8 T Cell Infiltration in Cervical Cancer.
LncRNA RNA Component of Mitochondrial RNA-Processing Endoribonuclease Promotes AKT-Dependent Breast Cancer Growth and Migration by Trapping MicroRNA-206.
PRDM16 Inhibits Cell Proliferation and Migration via Epithelial-to-Mesenchymal Transition by Directly Targeting Pyruvate Carboxylase in Papillary Thyroid Cancer.
Macrophage-Mediated Bone Formation in Scaffolds Modified With MSC-Derived Extracellular Matrix Is Dependent on the Migration Inhibitory Factor Signaling Pathway.
Depletion of Demethylase KDM6 Enhances Early Neuroectoderm Commitment of Human PSCs.
Design, Synthesis, and Biological Evaluation of Pyrano[2,3-c]-pyrazole-Based RalA Inhibitors Against Hepatocellular Carcinoma.
Cardiac Overexpression of XIN Prevents Dilated Cardiomyopathy Caused by TNNT2 ΔK210 Mutation.
LncRNA CRNDE Promotes ATG4B-Mediated Autophagy and Alleviates the Sensitivity of Sorafenib in Hepatocellular Carcinoma Cells.
GDF11 Alleviates Pathological Myocardial Remodeling in Diabetic Cardiomyopathy Through SIRT1-Dependent Regulation of Oxidative Stress and Apoptosis.
SUN5 Interacting With Nesprin3 Plays an Essential Role in Sperm Head-to-Tail Linkage: Research on Sun5 Gene Knockout Mice.
Autophagy-Related LC3 Accumulation Interacted Directly With LIR Containing RIPK1 and RIPK3, Stimulating Necroptosis in Hypoxic Cardiomyocytes.
Quiescin Sulfhydryl Oxidase 2 Overexpression Predicts Poor Prognosis and Tumor Progression in Patients With Colorectal Cancer: A Study Based on Data Mining and Clinical Verification.
NudC L279P Mutation Destabilizes Filamin A by Inhibiting the Hsp90 Chaperoning Pathway and Suppresses Cell Migration.
Exosomal miR-2276-5p in Plasma Is a Potential Diagnostic and Prognostic Biomarker in Glioma.
Comprehensive Analysis of the Transcriptome-Wide m6A Methylome in Pterygium by MeRIP Sequencing.
α-Enolase Lies Downstream of mTOR/HIF1α and Promotes Thyroid Carcinoma Progression by Regulating CST1.
Force-Induced Autophagy in Periodontal Ligament Stem Cells Modulates M1 Macrophage Polarization via AKT Signaling.
SP1-Mediated Upregulation of Long Noncoding RNA ZFAS1 Involved in Non-syndromic Cleft Lip and Palate via Inactivating WNT/β-Catenin Signaling Pathway.
NLGN3 Upregulates Expression of ADAM10 to Promote the Cleavage of NLGN3 via Activating the LYN Pathway in Human Gliomas.
The E3 Ligase PIAS1 Regulates p53 Sumoylation to Control Stress-Induced Apoptosis of Lens Epithelial Cells Through the Proapoptotic Regulator Bax.
Platelet-Rich Plasma Induces Autophagy and Promotes Regeneration in Human Dental Pulp Cells.
BRD7 Promotes Cell Proliferation and Tumor Growth Through Stabilization of c-Myc in Colorectal Cancer.
BMSC-Derived Small Extracellular Vesicles Induce Cartilage Reconstruction of Temporomandibular Joint Osteoarthritis via Autotaxin-YAP Signaling Axis.
LINC00511/miRNA-143-3p Modulates Apoptosis and Malignant Phenotype of Bladder Carcinoma Cells via PCMT1.
Urea as a By-Product of Ammonia Metabolism Can Be a Potential Serum Biomarker of Hepatocellular Carcinoma.
Inhibition of JAK-STAT Signaling Pathway Alleviates Age-Related Phenotypes in Tendon Stem/Progenitor Cells.
β-Arrestin1 Promotes Colorectal Cancer Metastasis Through GSK-3β/β-Catenin Signaling- Mediated Epithelial-to-Mesenchymal Transition.
Cartilage Endplate Stem Cells Transdifferentiate Into Nucleus Pulposus Cells via Autocrine Exosomes.
CORO6 Promotes Cell Growth and Invasion of Clear Cell Renal Cell Carcinoma via Activation of WNT Signaling.
TAp63α Is Involved in Tobacco Smoke-Induced Lung Cancer EMT and the Anti-cancer Activity of Curcumin via miR-19 Transcriptional Suppression.
Hypoxia-Induced LIN28A mRNA Promotes the Metastasis of Colon Cancer in a Protein-Coding-Independent Manner.
A Novel CpG Methylation Risk Indicator for Predicting Prognosis in Bladder Cancer.
Exosomal miR-3682-3p Suppresses Angiogenesis by Targeting ANGPT1 via the RAS-MEK1/2-ERK1/2 Pathway in Hepatocellular Carcinoma.
Establishment of an Efficient Primary Culture System for Human Hair Follicle Stem Cells Using the Rho-Associated Protein Kinase Inhibitor Y-27632.
Grb2 Induces Cardiorenal Syndrome Type 3: Roles of IL-6, Cardiomyocyte Bioenergetics, and Akt/mTOR Pathway.
Extracellular Vesicles Carry lncRNA SNHG16 to Promote Metastasis of Breast Cancer Cells via the miR-892b/PPAPDC1A Axis.
The Protective Effect of 1,25(OH)2D3 on Myocardial Function is Mediated via Sirtuin 3-Regulated Fatty Acid Metabolism.
LUZP1 Controls Cell Division, Migration and Invasion Through Regulation of the Actin Cytoskeleton.
High-Fat Diet Induced Gut Microbiota Alterations Associating With Ghrelin/Jak2/Stat3 Up-Regulation to Promote Benign Prostatic Hyperplasia Development.
Hypoglycemic Efficacy of Rh-aFGF Variants in Treatment of Diabetes in ZDF Rats.
Deficiency of Sirtuin 1 Impedes Endometrial Decidualization in Recurrent Implantation Failure Patients.
Retinoic Acid Signaling Plays a Crucial Role in Excessive Caffeine Intake-Disturbed Apoptosis and Differentiation of Myogenic Progenitors.
MNSFβ Promotes the Proliferation and Migration of Human Extravillous Trophoblast Cells and the Villus Expression Level of MNSFβ Is Decreased in Recurrent Miscarriage Patients.
Microenvironment Stiffness Amplifies Post-ischemia Heart Regeneration in Response to Exogenous Extracellular Matrix Proteins in Neonatal Mice.
Maslinic Acid Attenuates Ischemia/Reperfusion Injury-Induced Myocardial Inflammation and Apoptosis by Regulating HMGB1-TLR4 Axis.
Vanadium Induces Oxidative Stress and Mitochondrial Quality Control Disorder in the Heart of Ducks.
Methylation and Expression of the Exercise-Related TLR1 Gene Is Associated With Low Grade Glioma Prognosis and Outcome.
Comprehensive Analysis of REST/NRSF Gene in Glioma and Its ceRNA Network Identification.
S-Propargyl-Cysteine Attenuates Diabetic Cardiomyopathy in db/db Mice Through Activation of Cardiac Insulin Receptor Signaling.
PIEZO1 Ion Channel Mediates Ionizing Radiation-Induced Pulmonary Endothelial Cell Ferroptosis via Ca2+/Calpain/VE-Cadherin Signaling.
Developmental Angiogenesis Requires the Mitochondrial Phenylalanyl-tRNA Synthetase.
MiR-3064 in Epicardial Adipose-Derived Exosomes Targets Neuronatin to Regulate Adipogenic Differentiation of Epicardial Adipose Stem Cells.
CUX1 Facilitates the Development of Oncogenic Properties Via Activating Wnt/β-Catenin Signaling Pathway in Glioma.
Expression and Functional Analysis of lncRNAs Involved in Platelet-Derived Growth Factor-BB-Induced Proliferation of Human Aortic Smooth Muscle Cells.
Traditional Chinese Medication Qiliqiangxin Attenuates Diabetic Cardiomyopathy via Activating PPARγ.
ZEB1 Mediates Bone Marrow Mesenchymal Stem Cell Osteogenic Differentiation Partly via Wnt/β-Catenin Signaling.
Whole-Transcriptome Analysis of LncRNAs Mediated ceRNA Regulation in Granulosa Cells Isolated From Healthy and Atresia Follicles of Chinese Buffalo.
CRISPR/dCas9-Mediated Parkin Inhibition Impairs Mitophagy and Aggravates Apoptosis of Rat Nucleus Pulposus Cells Under Oxidative Stress.
Pharmacological Activating Transcription Factor 6 Activation Is Beneficial for Liver Retrieval With ex vivo Normothermic Mechanical Perfusion From Cardiac Dead Donor Rats.
Identification of Proteomic Signatures in Chronic Obstructive Pulmonary Disease Emphysematous Phenotype.
WDR45 Mutation Impairs the Autophagic Degradation of Transferrin Receptor and Promotes Ferroptosis.
Antiretroviral Drugs Regulate Epigenetic Modification of Cardiac Cells Through Modulation of H3K9 and H3K27 Acetylation.
Acitretin Promotes the Differentiation of Myeloid-Derived Suppressor Cells in the Treatment of Psoriasis.
Tanshinone IIA Combined With Cyclosporine A Alleviates Lung Apoptosis Induced by Renal Ischemia-Reperfusion in Obese Rats.
CYP2C8 Suppress Proliferation, Migration, Invasion and Sorafenib Resistance of Hepatocellular Carcinoma via PI3K/Akt/p27kip1 Axis.
Cannabisin D from Sinomenium Acutum Inhibits Proliferation and Migration of Glioblastoma Cells through MAPKs Signaling.
The mechanism and candidate compounds of aged citrus peel (chenpi) preventing chronic obstructive pulmonary disease and its progression to lung cancer.
Disulfiram Chelated with Copper Promotes Apoptosis in Osteosarcoma via ROS/Mitochondria Pathway.
Discovery and Verification of Key Liver Cancer Genes and Alternative Splicing Events Based on Second-Generation Sequencing Data Analysis.
Suppression of DLBCL Progression by the E3 Ligase Trim35 Is Mediated by CLOCK Degradation and NK Cell Infiltration.
TNPO1-Mediated Nuclear Import of FUBP1 Contributes to Tumor Immune Evasion by Increasing NRP1 Expression in Cervical Cancer.
MiR-21-3p Inhibits Adipose Browning by Targeting FGFR1 and Aggravates Atrial Fibrosis in Diabetes.
PIN1 Protects Hair Cells and Auditory HEI-OC1 Cells against Senescence by Inhibiting the PI3K/Akt/mTOR Pathway.
Lipidomic Alterations and PPARα Activation Induced by Resveratrol Lead to Reduction in Lesion Size in Endometriosis Models.
Y-Box Binding Protein 1 Regulates Angiogenesis in Bladder Cancer via miR-29b-3p-VEGFA Pathway.
VIP Stabilizes the Cytoskeleton of Schlemm's Canal Endothelia via Reducing Caspase-3 Mediated ZO-1 Endolysosomal Degradation.
Effect and Mechanism of LRP6 on Cardiac Myocyte Ferroptosis in Myocardial Infarction.
Tetrandrine Ameliorates Myocardial Ischemia Reperfusion Injury through miR-202-5p/TRPV2.
P2X7 Receptor Induces Pyroptotic Inflammation and Cartilage Degradation in Osteoarthritis via NF-κB/NLRP3 Crosstalk.
Oleanolic Acid Induces Autophagy and Apoptosis via the AMPK-mTOR Signaling Pathway in Colon Cancer.
Protective Effect of Xiao-Xu-Ming Decoction-Mediated Inhibition of ROS/NLRP3 Axis on Lipopolysaccharide-Induced Acute Lung Injury In Vitro and In Vivo.
Functional Analysis of Ectodysplasin-A Mutations in X-Linked Nonsyndromic Hypodontia and Possible Involvement of X-Chromosome Inactivation.
Wenxin Granules Regulate Endoplasmic Reticulum Stress Unfolded Protein Response and Improve Ventricular Remodeling on Rats with Myocardial Infarction.
Limonin Inhibits IL-1β-Induced Inflammation and Catabolism in Chondrocytes and Ameliorates Osteoarthritis by Activating Nrf2.
Pentoxifylline Can Reduce the Inflammation Caused by LPS after Inhibiting Autophagy in RAW264.7 Macrophage Cells.
RBM23 Drives Hepatocellular Carcinoma by Activating NF-κB Signaling Pathway.
Ganoderma lucidum Spore Polysaccharide Inhibits the Growth of Hepatocellular Carcinoma Cells by Altering Macrophage Polarity and Induction of Apoptosis.
Dendrobium officinale Regulates Fatty Acid Metabolism to Ameliorate Liver Lipid Accumulation in NAFLD Mice.
Nardosinone Alleviates Parkinson's Disease Symptoms in Mice by Regulating Dopamine D2 Receptor.
Ferroportin-Dependent Iron Homeostasis Protects against Oxidative Stress-Induced Nucleus Pulposus Cell Ferroptosis and Ameliorates Intervertebral Disc Degeneration In Vivo.
Melatonin Alleviates Contrast-Induced Acute Kidney Injury by Activation of Sirt3.
Exercise Reduces Morphine-Induced Hyperalgesia and Antinociceptive Tolerance.
Identification of Immune-Related Prognostic Biomarkers Associated with HPV-Positive Head and Neck Squamous Cell Carcinoma.
Tantalum Particles Induced Cytotoxic and Inflammatory Effects in Human Monocytes.
Serum Exosomes Derived from Irritable Bowel Syndrome Patient Increase Cell Permeability via Regulating miR-148b-5p/RGS2 Signaling in Human Colonic Epithelium Cells.
CDK12 Promotes Cervical Cancer Progression through Enhancing Macrophage Infiltration.
Oxalate Activates Autophagy to Induce Ferroptosis of Renal Tubular Epithelial Cells and Participates in the Formation of Kidney Stones.
HO-1/CO Maintains Intestinal Barrier Integrity through NF-κB/MLCK Pathway in Intestinal HO-1-/- Mice.
Babao Dan Reverses Multiple-Drug Resistance in Gastric Cancer Cells via Triggering Apoptosis and Autophagy and Inhibiting PI3K/AKT/mTOR Signaling.
lncRNA HHIP-AS1 Promotes the Osteogenic Differentiation Potential and Inhibits the Migration Ability of Periodontal Ligament Stem Cells.
Tubeimoside I Ameliorates Myocardial Ischemia-Reperfusion Injury through SIRT3-Dependent Regulation of Oxidative Stress and Apoptosis.
Heat Killed Salmonella typhimurium Protects Intestine Against Radiation Injury Through Wnt Signaling Pathway.
Essential Oil-Rich Chinese Formula Luofushan-Baicao Oil Inhibits the Infection of Influenza A Virus through the Regulation of NF-κB P65 and IRF3 Activation.
TIPE1 Suppresses Growth and Metastasis of Ovarian Cancer.
Pleckstrin-2 as a Prognostic Factor and Mediator of Gastric Cancer Progression.
LuQi Formula Regulates NLRP3 Inflammasome to Relieve Myocardial-Infarction-Induced Cardiac Remodeling in Mice.
CKAP2L, as an Independent Risk Factor, Closely Related to the Prognosis of Glioma.
Design, Synthesis, and Biological Evaluation of a Novel Aminothiol Compound as Potential Radioprotector.
The Dietary Supplement γ-Oryzanol Attenuates Hepatic Ischemia Reperfusion Injury via Inhibiting Endoplasmic Reticulum Stress and HMGB1/NLRP3 Inflammasome.
MCC950, the NLRP3 Inhibitor, Protects against Cartilage Degradation in a Mouse Model of Osteoarthritis.
Hypoxia Enhances Activity and Malignant Behaviors of Colorectal Cancer Cells through the STAT3/MicroRNA-19a/PTEN/PI3K/AKT Axis.
ULK1 Suppresses Osteoclast Differentiation and Bone Resorption via Inhibiting Syk-JNK through DOK3.
Danhong Injection and Trimetazidine Protect Cardiomyocytes and Enhance Calcium Handling after Myocardial Infarction.
Luteolin Improves Cyclophosphamide-Induced Cystitis through TXNIP/NLRP3 and NF-κB Pathways.
Mitoquinone Protects Podocytes from Angiotensin II-Induced Mitochondrial Dysfunction and Injury via the Keap1-Nrf2 Signaling Pathway.
Ivabradine Ameliorates Cardiac Function in Heart Failure with Preserved and Reduced Ejection Fraction via Upregulation of miR-133a.
circGLI3 Inhibits Oxidative Stress by Regulating the miR-339-5p/VEGFA Axis in IPEC-J2 Cells.
Inhibiting PP2Acα Promotes the Malignant Phenotype of Gastric Cancer Cells through the ATM/METTL3 Axis.
An Integrated Transcriptomics and Proteomics Analysis Implicates lncRNA MALAT1 in the Regulation of Lipid Metabolism.
Lack of WDFY4 Aggravates Ovalbumin-Induced Asthma via Enhanced Th2 Cell Differentiation.
Long noncoding RNA CEBPA-DT promotes cisplatin chemo-resistance through CEBPA/BCL2 mediated apoptosis in oral squamous cellular cancer.
The expression and clinical significance of TPM4 in hepatocellular carcinoma.
Dual-specificity Phosphatase 9 protects against Cardiac Hypertrophy by targeting ASK1.
GABAB receptor inhibits tumor progression and epithelial-mesenchymal transition via the regulation of Hippo/YAP1 pathway in colorectal cancer.
MicroRNA-135b/CAMK2D Axis Contribute to Malignant Progression of Gastric Cancer through EMT Process Remodeling.
NDRG1 regulates Filopodia-induced Colorectal Cancer invasiveness via modulating CDC42 activity.
YY1-modulated long non-coding RNA SNHG12 promotes gastric cancer metastasis by activating the miR-218-5p/YWHAZ axis.
PAK5-mediated AIF phosphorylation inhibits its nuclear translocation and promotes breast cancer tumorigenesis.
Aurka deficiency in the intestinal epithelium promotes age-induced obesity via propionate-mediated AKT activation.
Characteristics of the PI3K/AKT and MAPK/ERK pathways involved in the maintenance of self-renewal in lung cancer stem-like cells.
Novel biomarkers for post-contrast acute kidney injury identified from long non-coding RNA expression profiles.
Linc-KILH potentiates Notch1 signaling through inhibiting KRT19 phosphorylation and promotes the malignancy of hepatocellular carcinoma.
ITGB1 enhances the Radioresistance of human Non-small Cell Lung Cancer Cells by modulating the DNA damage response and YAP1-induced Epithelial-mesenchymal Transition.
Inhibition of PI3K/AKT signaling via ROS regulation is involved in Rhein-induced apoptosis and enhancement of oxaliplatin sensitivity in pancreatic cancer cells.
SOX13/TRIM11/YAP axis promotes the proliferation, migration and chemoresistance of anaplastic thyroid cancer.
MAD2B-mediated cell cycle reentry of podocytes is involved in the pathogenesis of FSGS.
Discovery of a novel HDACi structure that inhibits the proliferation of ovarian cancer cells in vivo and in vitro.
Downregulation of miR‑214-3p attenuates mesangial hypercellularity by targeting PTEN‑mediated JNK/c-Jun signaling in IgA nephropathy.
Genome-scale CRISPRa screening identifies MTX1 as a contributor for sorafenib resistance in hepatocellular carcinoma by augmenting autophagy.
CXCL16 Promotes Gastric Cancer Tumorigenesis via ADAM10-Dependent CXCL16/CXCR6 Axis and Activates Akt and MAPK Signaling Pathways.
Ailanthus Altissima-derived Ailanthone enhances Gastric Cancer Cell Apoptosis by Inducing the Repression of Base Excision Repair by Downregulating p23 Expression.
Novel Functions of CD147 in the Mitochondria Exacerbates Melanoma Metastasis.
COP9 Signalosome Subunit 3 Restricts Neuroinflammatory Responses During Cerebral Ischemia/Reperfusion Injury Through Stabilizing Suppressor of Cytokine Signaling 3 Protein.
Loss of miR-1469 expression mediates melanoma cell migration and invasion.
A novel mouse line with epididymal initial segment-specific expression of Cre recombinase driven by the endogenous Lcn9 promoter.
Modulation of inflammatory responses by fractalkine signaling in microglia.
Harmine inhibits breast cancer cell migration and invasion by inducing the degradation of Twist1.
High expression of ENPP1 in high-grade serous ovarian carcinoma predicts poor prognosis and as a molecular therapy target.
Downregulation of RAB7 and Caveolin-1 increases MMP-2 activity in renal tubular epithelial cells under hypoxic conditions.
Copper Nanoparticles Induce Oxidative Stress via the Heme Oxygenase 1 Signaling Pathway in vitro Studies.
Convallatoxin Promotes M2 Macrophage Polarization to Attenuate Atherosclerosis Through PPARγ-Integrin αvβ5 Signaling Pathway.
Astrocyte Pannexin 1 Suppresses LPS-Induced Inflammatory Responses to Protect Neuronal SH-SY5Y Cells.
Tetramethylpyrazine Alleviates Behavioral and Psychological Symptoms of Dementia Through Facilitating Hippocampal Synaptic Plasticity in Rats With Chronic Cerebral Hypoperfusion.
The Ghrelin/Growth Hormone Secretagogue Receptor System Is Involved in the Rapid and Sustained Antidepressant-Like Effect of Paeoniflorin.
Isoquercetin Improves Inflammatory Response in Rats Following Ischemic Stroke.
Activation of GPR18 by Resolvin D2 Relieves Pain and Improves Bladder Function in Cyclophosphamide-Induced Cystitis Through Inhibiting TRPV1.
Bardoxolone-Methyl Prevents Oxidative Stress-Mediated Apoptosis and Extracellular Matrix Degradation in vitro and Alleviates Osteoarthritis in vivo.
Puerarin Alleviates UUO-Induced Inflammation and Fibrosis by Regulating the NF-κB P65/STAT3 and TGFβ1/Smads Signaling Pathways.
Pentamidine Inhibits Ovarian Cancer Cell Proliferation and Migration by Maintaining Stability of PTEN in vitro.
The Effects of M1/M2 Macrophages on the mRNA Expression Profile of Diabetic Glomerular Endothelial Cells.
Inhibition of TGF-β2-induced migration and epithelial-mesenchymal transition in ARPE-19 by sulforaphane.
Effect of luteolin on apoptosis and vascular endothelial growth factor in human choroidal melanoma cells.
Maxing Shigan Decoction Mitigates Mycoplasma pneumonia-Induced Pyroptosis in A549 Cells via the NLRP3 Inflammasome.
LncRNA MCTP1-AS1 Regulates EMT Process in Endometrial Cancer by Targeting the miR-650/SMAD7 Axis.
Engeletin Protects Against TNF-α-Induced Apoptosis and Reactive Oxygen Species Generation in Chondrocytes and Alleviates Osteoarthritis in vivo.
Proteomic Profiling of Astrocytic O-GlcNAc Transferase-Related Proteins in the Medial Prefrontal Cortex.
Neutrophil Extracellular Traps Augmented Alveolar Macrophage Pyroptosis via AIM2 Inflammasome Activation in LPS-Induced ALI/ARDS.
A c-Met Inhibitor Suppresses Osteosarcoma Progression via the ERK1/2 Pathway in Human Osteosarcoma Cells.
Fatty Acid-Binding Protein 4 (FABP4) Suppresses Proliferation and Migration of Endometrial Cancer Cells via PI3K/Akt Pathway.
miR-944 Suppresses EGF-Induced EMT in Colorectal Cancer Cells by Directly Targeting GATA6.
Prognostic Implications of the Complement Protein C1Q and Its Correlation with Immune Infiltrates in Osteosarcoma.
An Apoptotic Gene Signature for the Prognosis of Hepatocellular Carcinoma.
Expression and Functional Relevance of ANXA1 in Hypopharyngeal Carcinoma with Lymph Node Metastasis.
Circular RNA ERBB2 Contributes to Proliferation and Migration of Airway Smooth Muscle Cells via miR-98-5p/IGF1R Signaling in Asthma.
FUT7 Promotes the Epithelial-Mesenchymal Transition and Immune Infiltration in Bladder Urothelial Carcinoma.
The cardioprotective effect of the sodium-glucose cotransporter 2 inhibitor dapagliflozin in rats with isoproterenol-induced cardiomyopathy.
Knockdown of VDAC1 alleviates the cognitive dysfunction secondary to sepsis-associated encephalopathy.
Qi Ling decoction reduces gastric cancer cell metastasis by inhibiting MMP-9 through the PI3K/Akt signaling pathway.
Inhibition of mu-opioid receptor suppresses proliferation of hepatocellular carcinoma cells via CD147-p53-MAPK cascade signaling pathway.
Positive Feedback Loop of Long Noncoding RNA OASL-IT1 and Innate Immune Response Restricts the Replication of Zika Virus in Epithelial A549 Cells.
Curcumin promotes the survival of ischemic random skin flaps via autophagy.
TET2 mediated demethylation is involved in the protective effect of triptolide on podocytes.
Sevoflurane prevents pulmonary vascular remodeling and right ventricular dysfunction in pulmonary arterial hypertension in rats.
Dura cells in the etiopathogenesis of Crouzon syndrome: the effects of FGFR2 mutations in the dura cells on the proliferation of osteoblasts through the hippo/YAP mediated transcriptional regulation pathway.
Combination effect of curcumin with docetaxel on the PI3K/AKT/mTOR pathway to induce autophagy and apoptosis in esophageal squamous cell carcinoma.
Downregulation of miRNA-451a Promotes the Differentiation of CD4+ T Cells towards Th2 Cells by Upregulating ETS1 in Childhood Asthma.
PARK2 attenuates house dust mite-induced inflammatory reaction, pyroptosis and barrier dysfunction in BEAS-2B cells by ubiquitinating NLRP3.
AGTR1 Inhibits the Progression of Lung Adenocarcinoma.
lncRNA AC007207.2 Promotes Malignant Properties of Osteosarcoma via the miR-1306-5p/SIRT7 Axis.
Stress Granules Modulate SYK to Cause Tau-Associated Neurocognitive Deterioration in 5XFAD Mouse After Anesthesia and Surgery.
Enriched Environment Attenuates Pyroptosis to Improve Functional Recovery After Cerebral Ischemia/Reperfusion Injury.
MALAT-1 is Associated with the Doxorubicin Resistance in U-2OS Osteosarcoma Cells.
Calcitriol Alleviates MPP+- and MPTP-Induced Parthanatos Through the VDR/PARP1 Pathway in the Model of Parkinson's Disease.
Intranasal Transplantation of Human Neural Stem Cells Ameliorates Alzheimer's Disease-Like Pathology in a Mouse Model.
Long-Term Administration of Triterpenoids From Ganoderma lucidum Mitigates Age-Associated Brain Physiological Decline via Regulating Sphingolipid Metabolism and Enhancing Autophagy in Mice.
The Non-peptide Angiotensin-(1-7) Mimic AVE 0991 Attenuates Delayed Neurocognitive Recovery After Laparotomy by Reducing Neuroinflammation and Restoring Blood-Brain Barrier Integrity in Aged Rats.
Plakophilin-2 Promotes Lung Adenocarcinoma Development via Enhancing Focal Adhesion and Epithelial-Mesenchymal Transition.
KLF7 Promotes Gastric Carcinogenesis Through Regulation of ANTXR1.
Columbamine-Mediated PTEN/AKT Signal Pathway Regulates the Progression of Glioma.
The Preliminary Study for Postoperative Radiotherapy Survival Associated with RUNX3 and TLR9 Expression in Lung Cancer.
Overexpression of Taspase 1 Predicts Poor Prognosis in Patients with Hepatocellular Carcinoma.
Identification of TRIM56 as a Potential Biomarker for Lung Adenocarcinoma.
Identification and validation of the clinical roles of the VHL-related LncRNAs in clear cell renal cell carcinoma.
SCARA5 inhibits gastric cancer progression via epithelial-mesenchymal transition suppression.
Peri-tumoral brain edema associated with glioblastoma correlates with tumor recurrence.
Long non-coding RNA SNHG25 promotes epithelial ovarian cancer progression by up-regulating COMP.
Decreased interferon regulatory factor 6 expression due to DNA hypermethylation predicts an unfavorable prognosis in clear cell renal cell carcinoma.
FGF14-AS2 accelerates tumorigenesis in glioma by forming a feedback loop with miR-320a/E2F1 axis.
RUNX1 regulates the proliferation and chemoresistance of colorectal cancer through the Hedgehog signaling pathway.
Effect of EG00229 on Radiation Resistance of Lung Adenocarcinoma Cells.
miR-552 promotes the proliferation and metastasis of cervical cancer cells through targeting MUC15 pathway.
Lipid Storage and Interferon Response Determine the Phenotype of Ground Glass Hepatocytes in Mice and Humans.
Co-overexpression of RIOK1 and AKT1 as a prognostic risk factor in glioma.
MRPS17 promotes invasion and metastasis through PI3K/AKT signal pathway and could be potential prognostic marker for gastric cancer.
EIF5A expression and its role as a potential diagnostic biomarker in hepatocellular carcinoma.
Demethylzelasteral inhibits proliferation and EMT via repressing Wnt/β-catenin signaling in esophageal squamous cell carcinoma.
BCI Suppresses RANKL-Mediated Osteoclastogenesis and Alleviates Ovariectomy-Induced Bone Loss.
Histone H2A Nuclear/Cytoplasmic Trafficking Is Essential for Negative Regulation of Antiviral Immune Response and Lysosomal Degradation of TBK1 and IRF3.
SOAT1 Promotes Gastric Cancer Lymph Node Metastasis Through Lipid Synthesis.
Duhaldea pterocaula (Franch.) Anderb. Attenuates Nociception and Inflammation via GABAA Receptors.
Nox4 Promotes RANKL-Induced Autophagy and Osteoclastogenesis via Activating ROS/PERK/eIF-2α/ATF4 Pathway.
Chinese Herbal Preparation SaiLuoTong Alleviates Brain Ischemia via Nrf2 Antioxidation Pathway-Dependent Cerebral Microvascular Protection.
An Integrative Pharmacology Based Analysis of Refined Liuweiwuling Against Liver Injury: A Novel Component Combination and Hepaprotective Mechanism.
Disease-Modifying Anti-rheumatic Drug Prescription Baihu-Guizhi Decoction Attenuates Rheumatoid Arthritis via Suppressing Toll-Like Receptor 4-mediated NLRP3 Inflammasome Activation.
Remimazolam Protects Against LPS-Induced Endotoxicity Improving Survival of Endotoxemia Mice.
Clostridium butyricum Supplement Can Ameliorate the Intestinal Barrier Roles in Broiler Chickens Experimentally Infected With Clostridium perfringens.
Screening of a Small Molecule Compound Library Identifies Toosendanin as an Inhibitor Against Bunyavirus and SARS-CoV-2.
Activation of Yes-Associated Protein/PDZ-Binding Motif Pathway Contributes to Endothelial Dysfunction and Vascular Inflammation in AngiotensinII Hypertension.
Selective STAT3 Inhibitor Alantolactone Ameliorates Osteoarthritis via Regulating Chondrocyte Autophagy and Cartilage Homeostasis.
Fascin-1 is Highly Expressed Specifically in Microglia After Spinal Cord Injury and Regulates Microglial Migration.
VDR Signaling via the Enzyme NAT2 Inhibits Colorectal Cancer Progression.
Samotolisib Attenuates Acute Liver Injury Through Inhibiting Caspase-11-Mediated Pyroptosis Via Regulating E3 Ubiquitin Ligase Nedd4.
Huangqi Shengmai Yin Ameliorates Myocardial Fibrosis by Activating Sirtuin3 and Inhibiting TGF-β/Smad Pathway.
Extracellular CIRP Induces an Inflammatory Phenotype in Pulmonary Fibroblasts via TLR4.
ZnT8 Deficiency Protects From APAP-Induced Acute Liver Injury by Reducing Oxidative Stress Through Upregulating Hepatic Zinc and Metallothioneins.
Identification of a Novel Epigenetic Signature CHFR as a Potential Prognostic Gene Involved in Metastatic Clear Cell Renal Cell Carcinoma.
EGFR-IL-6 Signaling Axis Mediated the Inhibitory Effect of Methylseleninic Acid on Esophageal Squamous Cell Carcinoma.
Combined Administration of Vitamin D3 and Geniposide Is Less Effective than Single Use of Vitamin D3 or Geniposide in the Treatment of Ulcerative Colitis.
Mefunidone Ameliorates Bleomycin-Induced Pulmonary Fibrosis in Mice.
Sinensetin Reduces Osteoarthritis Pathology in the Tert-Butyl Hydroperoxide-Treated Chondrocytes and the Destabilization of the Medial Meniscus Model Mice via the AMPK/mTOR Signaling Pathway.
Azithromycin Attenuates Bleomycin-Induced Pulmonary Fibrosis Partly by Inhibiting the Expression of LOX and LOXL-2.
Novel Molecule Nell-1 Promotes the Angiogenic Differentiation of Dental Pulp Stem Cells.
Preexposure and Postexposure Prophylaxis of Rabies With Adeno-Associated Virus Expressing Virus-Neutralizing Antibody in Rodent Models.
RPL22 Overexpression Promotes Psoriasis-Like Lesion by Inducing Keratinocytes Abnormal Biological Behavior.
Screening and Identification of Key Genes for Activation of Islet Stellate Cell.
Characterization of the Potential Role of NTPCR in Epithelial Ovarian Cancer by Integrating Transcriptomic and Metabolomic Analysis.
Preclinical Investigation of Alpinetin in the Treatment of Cancer-Induced Cachexia via Activating PPARγ.
Overexpression of SHMT2 Predicts a Poor Prognosis and Promotes Tumor Cell Growth in Bladder Cancer.
Loganin Inhibits Angiotensin II-Induced Cardiac Hypertrophy Through the JAK2/STAT3 and NF-κB Signaling Pathways.
Traditional Chinese Medication Tongxinluo Attenuates Lipidosis in Ox-LDL-Stimulated Macrophages by Enhancing Beclin-1-Induced Autophagy.
SEC23A Is an Independent Prognostic Biomarker in Bladder Cancer Correlated With MAPK Signaling.
Pig Liver Esterases Hydrolyze Endocannabinoids and Promote Inflammatory Response.
Feasibility and Mechanism Analysis of Shenfu Injection in the Treatment of Idiopathic Pulmonary Fibrosis.
M2a Macrophage-Secreted CHI3L1 Promotes Extracellular Matrix Metabolic Imbalances via Activation of IL-13Rα2/MAPK Pathway in Rat Intervertebral Disc Degeneration.
Atractylodin Attenuates Dextran Sulfate Sodium-Induced Colitis by Alleviating Gut Microbiota Dysbiosis and Inhibiting Inflammatory Response Through the MAPK Pathway.
STAT3-Dependent Gene TRIM5γ Interacts With HBx Through a Zinc Binding Site on the BBox Domain.
Lipidomics Revealed Alteration of Sphingolipid Metabolism During the Reparative Phase After Myocardial Infarction Injury.
SARS-CoV-2 Membrane Protein Inhibits Type I Interferon Production Through Ubiquitin-Mediated Degradation of TBK1.
Targeting Glycogen Synthase Kinase 3 Beta Regulates CD47 Expression After Myocardial Infarction in Rats via the NF-κB Signaling Pathway.
Characterization of Two Loss-of-Function NF1 Variants in Chinese Patients and Potential Molecular Interpretations of Phenotypes.
DsbA-L Ameliorates Renal Injury Through the AMPK/NLRP3 Inflammasome Signaling Pathway in Diabetic Nephropathy.
The New PI3K/mTOR Inhibitor GNE-477 Inhibits the Malignant Behavior of Human Glioblastoma Cells.
Effect of Protein O-Mannosyltransferase (MSMEG_5447) on M. smegmatis and Its Survival in Macrophages.
Pulmonary Artery Smooth Muscle Cell Senescence Promotes the Proliferation of PASMCs by Paracrine IL-6 in Hypoxia-Induced Pulmonary Hypertension.
SARS-CoV-2 Accessory Protein ORF7b Mediates Tumor Necrosis Factor-α-Induced Apoptosis in Cells.
Interferon-Lambda 1 Inhibits Staphylococcus aureus Colonization in Human Primary Keratinocytes.
The Treatment of Rhodiola Mimics Exercise to Resist High-Fat Diet-Induced Muscle Dysfunction via Sirtuin1-Dependent Mechanisms.
Anti-Hyperuricemic and Nephroprotective Effects of Dihydroberberine in Potassium Oxonate- and Hypoxanthine-Induced Hyperuricemic Mice.
Bellidifolin Ameliorates Isoprenaline-Induced Myocardial Fibrosis by Regulating TGF-β1/Smads and p38 Signaling and Preventing NR4A1 Cytoplasmic Localization.
Berberine Attenuates Chronic Atrophic Gastritis Induced by MNNG and Its Potential Mechanism.
Effects of Allicin on Late Sodium Current Caused by ΔKPQ-SCN5A Mutation in HEK293 Cells.
The Crucial Role of PPARγ-Egr-1-Pro-Inflammatory Mediators Axis in IgG Immune Complex-Induced Acute Lung Injury.
Repurposing of Pirfenidone (Anti-Pulmonary Fibrosis Drug) for Treatment of Rheumatoid Arthritis.
Jian-Pi-Yi-Shen Formula Ameliorates Oxidative Stress, Inflammation, and Apoptosis by Activating the Nrf2 Signaling in 5/6 Nephrectomized Rats.
Sinomenine Attenuated Capsaicin-Induced Increase in Cough Sensitivity in Guinea Pigs by Inhibiting SOX5/TRPV1 Axis and Inflammatory Response.
Remdesivir Inhibits Tubulointerstitial Fibrosis in Obstructed Kidneys.
Compound Dihuang Granule Inhibits Nigrostriatal Pathway Apoptosis in Parkinson's Disease by Suppressing the JNK/AP-1 Pathway.
MicroRNA-497 Reduction and Increase of Its Family Member MicroRNA-424 Lead to Dysregulation of Multiple Inflammation Related Genes in Synovial Fibroblasts With Rheumatoid Arthritis.
Hepatitis B Surface Antigen Suppresses the Activation of Nuclear Factor Kappa B Pathway via Interaction With the TAK1-TAB2 Complex.
Quercitrin Attenuates Acetaminophen-Induced Acute Liver Injury by Maintaining Mitochondrial Complex I Activity.
PRMT5 functionally associates with EZH2 to promote colorectal cancer progression through epigenetically repressing CDKN2B expression.
Inhibition of BAG3 enhances the anticancer effect of shikonin in hepatocellular carcinoma.
Honokiol induces ferroptosis in colon cancer cells by regulating GPX4 activity.
NONO phase separation enhances DNA damage repair by accelerating nuclear EGFR-induced DNA-PK activation.
Platelet-derived microvesicles induce calcium oscillations and promote VSMC migration via TRPV4.
Glycosylation of Siglec15 promotes immunoescape and tumor growth.
YY1-mediated reticulocalbin-2 upregulation promotes the hepatocellular carcinoma progression via activating MYC signaling.
TSL-1502, a glucuronide prodrug of a poly (ADP-ribose) polymerase (PARP) inhibitor, exhibits potent anti-tumor activity in preclinical models.
TM2D1 contributes the epithelial-mesenchymal transition of hepatocellular carcinoma via modulating AKT/β-catenin axis.
A Mitochondrial DNA Variant Elevates the Risk of Gallstone Disease by Altering Mitochondrial Function.
Loss of BRMS2 induces cell growth inhibition and translation capacity reduction in colorectal cancer cells.
S100A11 Promotes Liver Steatosis via FOXO1-Mediated Autophagy and Lipogenesis.
Exosome-mediated delivery of inflammation-responsive Il-10 mRNA for controlled atherosclerosis treatment.
Rapid design and development of CRISPR-Cas13a targeting SARS-CoV-2 spike protein.
Designer exosomes for targeted and efficient ferroptosis induction in cancer via chemo-photodynamic therapy.
TRPV2-spike protein interaction mediates the entry of SARS-CoV-2 into macrophages in febrile conditions.
Nanoparticle encapsulation of non-genotoxic p53 activator Inauhzin-C for improved therapeutic efficacy.
KAT6A, a novel regulator of β-catenin, promotes tumorigenicity and chemoresistance in ovarian cancer by acetylating COP1.
Relieving lipid accumulation through UCP1 suppresses the progression of acute kidney injury by promoting the AMPK/ULK1/autophagy pathway.
Cardiac telocytes inhibit cardiac microvascular endothelial cell apoptosis through exosomal miRNA-21-5p-targeted cdip1 silencing to improve angiogenesis following myocardial infarction.
The Circ_0001367/miR-545-3p/LUZP1 Axis Regulates Cell Proliferation, Migration and Invasion in Glioma Cells.
A Class of Protein-Coding RNAs Binds to Polycomb Repressive Complex 2 and Alters Histone Methylation.
DEAD-Box Helicase DDX6 Facilitated RIG-I-Mediated Type-I Interferon Response to EV71 Infection.
TFCP2 Overcomes Senescence by Cooperating With SREBP2 to Activate Cholesterol Synthesis in Pancreatic Cancer.
LncRNA LGALS8-AS1 Promotes Breast Cancer Metastasis Through miR-125b-5p/SOX12 Feedback Regulatory Network.
Siglec-15 Promotes Tumor Progression in Osteosarcoma via DUSP1/MAPK Pathway.
METTL3 Promotes the Resistance of Glioma to Temozolomide via Increasing MGMT and ANPG in a m6A Dependent Manner.
SPNS2 Downregulation Induces EMT and Promotes Colorectal Cancer Metastasis via Activating AKT Signaling Pathway.
TIPE2 Suppresses Malignancy of Pancreatic Cancer Through Inhibiting TGFβ1 Mediated Signaling Pathway.
Downregulation of miR-135b-5p Suppresses Progression of Esophageal Cancer and Contributes to the Effect of Cisplatin.
miR-1258 Attenuates Tumorigenesis Through Targeting E2F1 to Inhibit PCNA and MMP2 Transcription in Glioblastoma.
The Deubiquitinase USP39 Promotes ESCC Tumorigenesis Through Pre-mRNA Splicing of the mTORC2 Component Rictor.
Pinocembrin Inhibits the Proliferation and Metastasis of Breast Cancer via Suppression of the PI3K/AKT Signaling Pathway.
N2E4, a Monoclonal Antibody Targeting Neuropilin-2, Inhibits Tumor Growth and Metastasis in Pancreatic Ductal Adenocarcinoma via Suppressing FAK/Erk/HIF-1α Signaling.
Analysis of Long Noncoding RNAs in Aila-Induced Non-Small Cell Lung Cancer Inhibition.
MiR-489-3p Reduced Pancreatic Cancer Proliferation and Metastasis By Targeting PKM2 and LDHA Involving Glycolysis.
SLC1A4: A Powerful Prognostic Marker and Promising Therapeutic Target for HCC.
LncRNA SNHG8 Promotes Proliferation and Inhibits Apoptosis of Diffuse Large B-Cell Lymphoma via Sponging miR-335-5p.
Long Noncoding RNA SNHG12 Promotes Gastric Cancer Proliferation by Binding to HuR and Stabilizing YWHAZ Expression Through the AKT/GSK-3β Pathway.
The Overexpression of Acyl-CoA Medium-Chain Synthetase-3 (ACSM3) Suppresses the Ovarian Cancer Progression via the Inhibition of Integrin β1/AKT Signaling Pathway.
TFEB Promotes Prostate Cancer Progression via Regulating ABCA2-Dependent Lysosomal Biogenesis.
DDX19A Promotes Metastasis of Cervical Squamous Cell Carcinoma by Inducing NOX1-Mediated ROS Production.
circATP2B1 Promotes Aerobic Glycolysis in Gastric Cancer Cells Through Regulation of the miR-326 Gene Cluster.
Overexpressed Tumor Suppressor Exosomal miR-15a-5p in Cancer Cells Inhibits PD1 Expression in CD8+T Cells and Suppresses the Hepatocellular Carcinoma Progression.
Identification and Confirmation of the miR-30 Family as a Potential Central Player in Tobacco-Related Head and Neck Squamous Cell Carcinoma.
miR-4461 Regulates the Proliferation and Metastasis of Ovarian Cancer Cells and Cisplatin Resistance.
miR-139-5p Loss-Mediated WTAP Activation Contributes to Hepatocellular Carcinoma Progression by Promoting the Epithelial to Mesenchymal Transition.
PSMC2 Regulates Cell Cycle Progression Through the p21/Cyclin D1 Pathway and Predicts a Poor Prognosis in Human Hepatocellular Carcinoma.
The Role of Tim-3 on dNK Cells Dysfunction During Abnormal Pregnancy With Toxoplasma gondii Infection.
Bispecific c-Met/PD-L1 CAR-T Cells Have Enhanced Therapeutic Effects on Hepatocellular Carcinoma.
Schisandrin Restores the Amyloid β-Induced Impairments on Mitochondrial Function, Energy Metabolism, Biogenesis, and Dynamics in Rat Primary Hippocampal Neurons.
Preliminary therapeutic and mechanistic evaluation of S-allylmercapto-N-acetylcysteine in the treatment of pulmonary emphysema.
Protective effect and mechanism of nicotinamide adenine dinucleotide against optic neuritis in mice with experimental autoimmune encephalomyelitis.
ITPRIP promotes glioma progression by linking MYL9 to DAPK1 inhibition.
CPEB1 enhances erastin-induced ferroptosis in gastric cancer cells by suppressing twist1 expression.
ZMPSTE24 Regulates SARS-CoV-2 Spike Protein-enhanced Expression of Endothelial PAI-1.
MiR-499a prevents astrocytes mediated inflammation in ischemic stroke by targeting PTEN.
Riluzole does not ameliorate disease caused by cytoplasmic TDP-43 in a mouse model of amyotrophic lateral sclerosis.
TAZ as a novel regulator of oxidative damage in decidualization via Nrf2/ARE/Foxo1 pathway.
Activation of Transient Receptor Potential Ankyrin 1 and Vanilloid 1 Channels Promotes Odontogenic Differentiation of Human Dental Pulp Cells.
Identifying miRNA modules associated with progression of keloids through weighted gene co-expression network analysis and experimental validation in vitro.
miR-138 inhibits epithelial-mesenchymal transition in silica-induced pulmonary fibrosis by regulating ZEB2.
miRNA‑7515 suppresses pancreatic cancer cell proliferation, migration and invasion via downregulating IGF‑1 expression.
Chronic stress promotes glioma cell proliferation via the PI3K/Akt signaling pathway.
MicroRNA-214 contributes to Ang II-induced cardiac hypertrophy by targeting SIRT3 to provoke mitochondrial malfunction.
Genetically encoded FRET fluorescent sensor designed for detecting MOF histone acetyltransferase activity in vitro and in living cells.
The scaffold protein IQGAP1 links heat-induced stress signals to alternative splicing regulation in gastric cancer cells.
miR-351-3p promotes rat amniotic fluid-derived mesenchymal stromal cell proliferation via targeting the coding sequence of Abca4.
FSH modulated cartilage ECM metabolism by targeting the PKA/CREB/SOX9 pathway.
miRNA-10a-5p inhibits cell metastasis in hepatocellular carcinoma via targeting SKA1.
Triclosan regulates the Nrf2/HO-1 pathway through the PI3K/Akt/JNK signaling cascade to induce oxidative damage in neurons.
TRIP13 exerts a cancer-promoting role in cervical cancer by enhancing Wnt/β-catenin signaling via ACTN4.
Hsp70 chaperones TDP-43 in dynamic, liquid-like phase and prevents it from amyloid aggregation.
The deubiquitinase USP10 restores PTEN activity and inhibits non-small cell lung cancer cell proliferation.
AMPK phosphorylates PPARδ to mediate its stabilization, inhibit glucose and glutamine uptake and colon tumor growth.
The inhibitory effect of the deubiquitinase cylindromatosis (CYLD) on inflammatory responses in human gingival fibroblasts.
Human forebrain endothelial cell therapy for psychiatric disorders.
N-3 polyunsaturated fatty acids promote astrocyte differentiation and neurotrophin production independent of cAMP in patient-derived neural stem cells.
DNM3OS regulates GAPDH expression and influences the molecular pathogenesis of Huntington's disease.
The effects of NCBP3 on METTL3-mediated m6A RNA methylation to enhance translation process in hypoxic cardiomyocytes.
Effects of different intensities of continuous training on vascular inflammation and oxidative stress in spontaneously hypertensive rats.
Abdominal paracentesis drainage attenuates intestinal mucosal barrier damage through macrophage polarization in severe acute pancreatitis.
miR‑140‑5p alleviates mouse liver ischemia/reperfusion injury by targeting CAPN1.
Endoglin deficiency impairs VEGFR2 but not FGFR1 or TIE2 activation and alters VEGF-mediated cellular responses in human primary endothelial cells.
PDIA6 promotes pancreatic cancer progression and immune escape through CSN5-mediated deubiquitination of β-catenin and PD-L1.
Human Bone Mesenchymal Stem Cell-Derived Exosomes Inhibit IL-1β-Induced Inflammation in Osteoarthritis Chondrocytes.
OGT regulated O-GlcNacylation promotes migration and invasion by activating IL-6/STAT3 signaling in NSCLC cells.
PPP1CA/YAP/GS/Gln/mTORC1 pathway activates retinal Müller cells during diabetic retinopathy.
Interleukin-4 protects mice against lethal influenza and Streptococcus pneumoniae co-infected pneumonia.
MeCP2 prevents age-associated cognitive decline via restoring synaptic plasticity in a senescence-accelerated mouse model.
P76RBE silencing inhibits ovarian cancer cell proliferation, migration, and invasion via suppressing the integrin β1/NF-κB pathway.
Photoresponsive PAMAM-Assembled Nanocarrier Loaded with Autophagy Inhibitor for Synergistic Cancer Therapy.
Orf Virus ORF120 Protein Positively Regulates the NF-κB Pathway by Interacting with G3BP1.
NSUN2 modified by SUMO-2/3 promotes gastric cancer progression and regulates mRNA m5C methylation.
HSP90 acts as a senomorphic target in senescent retinal pigmental epithelial cells.
Microglia modulation with 1070-nm light attenuates Aβ burden and cognitive impairment in Alzheimer's disease mouse model.
Cilium induction triggers differentiation of glioma stem cells.
m6A demethylase ALKBH5 suppression contributes to esophageal squamous cell carcinoma progression.
The genomic architecture of EBV and infected gastric tissue from precursor lesions to carcinoma.
A ciliopathy complex builds distal appendages to initiate ciliogenesis.
TDP-43 mediates SREBF2-regulated gene expression required for oligodendrocyte myelination.
Live Combined B. subtilis and E. faecium Alleviate Liver Inflammation, Improve Intestinal Barrier Function, and Modulate Gut Microbiota in Mice with Non-Alcoholic Fatty Liver Disease.
Curcumol inhibits encephalomyocarditis virus by promoting IFN-β secretion.
Stimulation of ROS Generation by Extract of Warburgia ugandensis Leading to G0/G1 Cell Cycle Arrest and Antiproliferation in A549 Cells.
HIF-1α/JMJD1A signaling regulates inflammation and oxidative stress following hyperglycemia and hypoxia-induced vascular cell injury.
Proximity Labeling, Quantitative Proteomics, and Biochemical Studies Revealed the Molecular Mechanism for the Inhibitory Effect of Indisulam on the Proliferation of Gastric Cancer Cells.
Supervillin Contributes to LPS-induced Inflammatory Response in THP-1 Cell-derived Macrophages.
Inhibition of DNMT-1 alleviates ferroptosis through NCOA4 mediated ferritinophagy during diabetes myocardial ischemia/reperfusion injury.
A Versatile Nanoplatform for Broad-Spectrum Immunotherapy by Reversing the Tumor Microenvironment.
Therapeutic Interaction of Apatinib and Chidamide in T-Cell Acute Lymphoblastic Leukemia through Interference with Mitochondria Associated Biogenesis and Intrinsic Apoptosis.
A Novel Calpain Inhibitor Compound Has Protective Effects on a Zebrafish Model of Spinocerebellar Ataxia Type 3.
Exosomal microRNA-588 from M2 polarized macrophages contributes to cisplatin resistance of gastric cancer cells.
Engineering Extracellular Vesicles Restore the Impaired Cellular Uptake and Attenuate Intervertebral Disc Degeneration.
Dual Inhibition of Endoplasmic Reticulum Stress and Oxidation Stress Manipulates the Polarization of Macrophages under Hypoxia to Sensitize Immunotherapy.
Regulatory variants at 2q33.1 confer schizophrenia risk by modulating distal gene TYW5 expression.
Phenotypic and genotypic changes in obesity and type 2 diabetes of male KK mice with aging.
Changes in energy metabolism and respiration in different tracheal narrowing in rats.
Protective effects of Huang-Lian-Jie-Du Decoction on diabetic nephropathy through regulating AGEs/RAGE/Akt/Nrf2 pathway and metabolic profiling in db/db mice.
Macrophage-mediated multi-mode drug release system for photothermal combined with anti-inflammatory therapy against postoperative recurrence of triple negative breast cancer.
EZH2 Inhibitor Enhances the STING Agonist‒Induced Antitumor Immunity in Melanoma.
A novel pyrrole-imidazole polyamide targets Aurora kinase A and suppresses tumor growth in vivo.
Metabolic nuclear receptors coordinate energy metabolism to regulate Sox9+ hepatocyte fate.
Downregulation of acylglycerol kinase suppresses high-glucose-induced endothelial-mesenchymal transition in human retinal microvascular endothelial cells through regulating the LPAR1/TGF-β/Notch signaling pathway.
Costunolide Loaded in pH-Responsive Mesoporous Silica Nanoparticles for Increased Stability and an Enhanced Anti-Fibrotic Effect.
Transgelin-2 interacts with CD44 to regulate Notch1 signaling pathway and participates in colorectal cancer proliferation and migration.
Nuclear speckle specific hnRNP D-like prevents age- and AD-related cognitive decline by modulating RNA splicing.
Xenon Nanobubbles for the Image-Guided Preemptive Treatment of Acute Ischemic Stroke via Neuroprotection and Microcirculatory Restoration.
GPCR-mediated EGFR transactivation ameliorates skin toxicities induced by afatinib.
Ferroptosis-related lncRNA pairs to predict the clinical outcome and molecular characteristics of pancreatic ductal adenocarcinoma.
The STING-IRF3 pathway contributes to paraquat-induced acute lung injury.
CD36 and DGAT2 facilitate the lipid-lowering effect of chitooligosaccharides via fatty acid intake and triglyceride synthesis signaling.
Isonicotinylation is a histone mark induced by the anti-tuberculosis first-line drug isoniazid.
RIOK2 Inhibitor NSC139021 Exerts Anti-Tumor Effects on Glioblastoma via Inducing Skp2-Mediated Cell Cycle Arrest and Apoptosis.
Lactobacillus johnsonii L531 Alleviates the Damage Caused by Salmonella Typhimurium via Inhibiting TLR4, NF-κB, and NLRP3 Inflammasome Signaling Pathways.
MYO10 drives genomic instability and inflammation in cancer.
Isopsoralen ameliorates rheumatoid arthritis by targeting MIF.
Flunarizine suppresses Mycobacterium tuberculosis growth via calmodulin-dependent phagosome maturation.
MicroRNA-550a-3-5p controls the brain metastasis of lung cancer by directly targeting YAP1.
EETs/sEHi alleviates nociception by blocking the crosslink between endoplasmic reticulum stress and neuroinflammation in a central poststroke pain model.
PRMT5 regulates cell pyroptosis by silencing CASP1 in multiple myeloma.
Latcripin-7A from Lentinula edodes C91-3 induces apoptosis, autophagy, and cell cycle arrest at G1 phase in human gastric cancer cells via inhibiting PI3K/Akt/mTOR signaling.
Round Scad-Derived Octapeptide WCPFSRSF Confers Neuroprotection by Regulating Akt/Nrf2/NFκB Signaling.
The protection of selenium against cadmium-induced mitophagy via modulating nuclear xenobiotic receptors response and oxidative stress in the liver of rabbits.
Co-exposure to BPA and DEHP enhances susceptibility of mammary tumors via up-regulating Esr1/HDAC6 pathway in female rats.
PM2.5-induced lung injury is attenuated in macrophage-specific NLRP3 deficient mice.
Physiologically detectable bisphenol A impairs human sperm functions by reducing protein-tyrosine phosphorylation.
Sigma-1 receptor regulates mitophagy in dopaminergic neurons and contributes to dopaminergic protection.
Scoparone inhibits pancreatic cancer through PI3K/Akt signaling pathway.
Quercitrin Rapidly Alleviated Depression-like Behaviors in Lipopolysaccharide-Treated Mice: The Involvement of PI3K/AKT/NF-κB Signaling Suppression and CREB/BDNF Signaling Restoration in the Hippocampus.
Circular RNA ZNF609 enhances proliferation and glycolysis during glioma progression by miR-378b/SLC2A1 axis.
Asiatic acid alleviates ischemic myocardial injury in mice by modulating mitophagy- and glycophagy-based energy metabolism.
Protective Effects and Mechanisms of Procyanidins on Parkinson's Disease In Vivo and In Vitro.
Genome-wide mRNA profiling identifies the NRF2-regulated lymphocyte oxidative stress status in patients with silicosis.
TNFSF9 promotes metastasis of pancreatic cancer through Wnt/Snail signaling and M2 polarization of macrophages.
LPCAT1 reprogramming cholesterol metabolism promotes the progression of esophageal squamous cell carcinoma.
Hypoxia regulates overall mRNA homeostasis by inducing Met1-linked linear ubiquitination of AGO2 in cancer cells.
Ketamine ameliorates depressive-like behaviors in mice through increasing glucose uptake regulated by the ERK/GLUT3 signaling pathway.
Phosphorylated PAMAM dendrimers: an analog of dentin non-collagenous proteins, enhancing the osteo/odontogenic differentiation of dental pulp stem cells.
2,5-dimethyl celecoxib induces apoptosis and autophagy via activation of ROS/JNK axis in nasopharyngeal carcinoma cells.
A dual-role of SARS-CoV-2 nucleocapsid protein in regulating innate immune response.
MIER3 induces epithelial-mesenchymal transition and promotes breast cancer cell aggressiveness via forming a co-repressor complex with HDAC1/HDAC2/Snail.
Differential expression of microRNAs in human endometrium after implantation of an intrauterine contraceptive device containing copper.
Formosanin C attenuates lipopolysaccharide-induced inflammation through nuclear factor-κB inhibition in macrophages.
A general role for TANGO1, encoded by MIA3, in secretory pathway organization and function.
CLEC5A knockdown protects against cardiac dysfunction after myocardial infarction by suppressing macrophage polarization, NLRP3 inflammasome activation, and pyroptosis.
Inhibition of YAP activation attenuates renal injury and fibrosis in angiotensin II hypertensive mice.
Iguratimod decreases bleomycin-induced pulmonary fibrosis in association with inhibition of TNF-α in mice.
A botanical dietary supplement from white peony and licorice attenuates nonalcoholic fatty liver disease by modulating gut microbiota and reducing inflammation.
USP41 promotes breast cancer via regulating RACK1.
MYO1B enhances colorectal cancer metastasis by promoting the F-actin rearrangement and focal adhesion assembly via RhoA/ROCK/FAK signaling.
MET overexpression contributes to STAT4-PD-L1 signaling activation associated with tumor-associated, macrophages-mediated immunosuppression in primary glioblastomas.
Concentrated growth factor regulates the macrophage-mediated immune response.
YAP drives fate conversion and chemoresistance of small cell lung cancer.
Distinct pathogenic mechanisms of various RARS1 mutations in Pelizaeus-Merzbacher-like disease.
Establishment of a second generation homozygous CRISPRa human induced pluripotent stem cell (hiPSC) line for enhanced levels of endogenous gene activation.
Serine/threonine kinase 17b (STK17B) signalling regulates Purkinje cell dendritic development and is altered in multiple spinocerebellar ataxias.
ErbB4 mediates amyloid β-induced neurotoxicity through JNK/tau pathway activation: Implications for Alzheimer's disease.
Functional expression of TRPA1 channel, TRPV1 channel and TMEM100 in human odontoblasts.
GFI1 promotes the proliferation and migration of esophageal squamous cell carcinoma cells through the inhibition of SOCS1 expression.
Lactate and glutamine support NADPH generation in cancer cells under glucose deprived conditions.
Mono-macrophage-Derived MANF Alleviates Bacterial Myocarditis by Inhibiting NF-kappaB Activation and Myocardial Inflammation.
Cystatin F acts as a mediator of immune suppression in glioblastoma.
Gossypol, a novel modulator of VCP, induces autophagic degradation of mutant huntingtin by promoting the formation of VCP/p97-LC3-mHTT complex.
Nicotinamide phosphoribosyltransferase inhibitor ameliorates mouse aging-induced cognitive impairment.
High-content screening of diterpenoids from Isodon species as autophagy modulators and the functional study of their antiviral activities.
Role of Intracellular Distribution of Feline and Bovine SAMHD1 Proteins in Lentiviral Restriction.
SETD8 involved in the progression of inflammatory bowel disease via epigenetically regulating p62 expression.
Therapeutic potential of isobavachalcone, a natural flavonoid, in murine experimental colitis by inhibiting NF-κB p65.
Pericytes augment glioblastoma cell resistance to temozolomide through CCL5-CCR5 paracrine signaling.
Bakuchiol ameliorates cerebral ischemia-reperfusion injury by modulating NLRP3 inflammasome and Nrf2 signaling.
Vitamin D decreases Porphyromonas gingivalis internalized into macrophages by promoting autophagy.
High-Throughput Screening to Identify Small Molecules That Selectively Inhibit APOL1 Protein Level in Podocytes.
Oridonin prevents oxidative stress-induced endothelial injury via promoting Nrf-2 pathway in ischaemic stroke.
Hydrogen sulphide reduced the accumulation of lipid droplets in cardiac tissues of db/db mice via Hrd1 S-sulfhydration.
SPOP promotes CDCA5 degradation to regulate prostate cancer progression via the AKT pathway.
Knockdown of ALDH1A3 reduces breast cancer stem cell marker CD44 via the miR-7-TGFBR2-Smad3-CD44 regulatory axis.
Establishment of incontinence-associated dermatitis rat models and assessment of the therapeutic effects of zinc oxide, painless skin protective film and silicone dressing.
The adjuvanticity of manganese for microbial vaccines via activating the IRF5 signaling pathway.
PPARα agonist WY-14,643 induces adipose atrophy and fails to blunt chronic ethanol-induced hepatic fat accumulation in mice lacking adipose FGFR1.
Nestin Is Required for Spindle Assembly and Cell-Cycle Progression in Glioblastoma Cells.
Membrane-Associated RING-CH 8 Functions as a Novel PD-L1 E3 Ligase to Mediate PD-L1 Degradation Induced by EGFR Inhibitors.
4,4'-Dimethoxychalcone regulates redox homeostasis by targeting riboflavin metabolism in Parkinson's disease therapy.
TSPAN1 promotes autophagy flux and mediates cooperation between WNT-CTNNB1 signaling and autophagy via the MIR454-FAM83A-TSPAN1 axis in pancreatic cancer.
Intrinsic bioactivity of black phosphorus nanomaterials on mitotic centrosome destabilization through suppression of PLK1 kinase.
Inhibition of sEH via stabilizing the level of EETs alleviated Alzheimer's disease through GSK3β signaling pathway.
Inhibition of autophagy with Chloroquine enhanced apoptosis induced by 5-aminolevulinic acid-photodynamic therapy in secondary hyperparathyroidism primary cells and organoids.
Synergic radiosensitization of sinomenine hydrochloride and radioiodine on human papillary thyroid carcinoma cells.
ATG16L2 overexpression is associated with a good prognosis in colorectal cancer.
KIF2C: a novel link between Wnt/β-catenin and mTORC1 signaling in the pathogenesis of hepatocellular carcinoma.
Travelling ultrasound promotes vasculogenesis of three-dimensional-monocultured human umbilical vein endothelial cells.
Transcription factor POU4F2 promotes colorectal cancer cell migration and invasion through hedgehog-mediated epithelial-mesenchymal transition.
PD0325901, an ERK inhibitor, enhances the efficacy of PD-1 inhibitor in non-small cell lung carcinoma.
Cordycepin inhibits cell senescence by ameliorating lysosomal dysfunction and inducing autophagy through the AMPK and mTOR-p70S6K pathway.
Curcumin attenuates Adriamycin-resistance of acute myeloid leukemia by inhibiting the lncRNA HOTAIR/miR-20a-5p/WT1 axis.
FNDC4 acts as an extracellular factor to promote the invasiveness of hepatocellular carcinoma partly via the PI3K/Akt signalling pathway.
Myosin 1f-mediated activation of microglia contributes to the photoreceptor degeneration in a mouse model of retinal detachment.
Serum Level of Tumor-Overexpressed AGR2 Is Significantly Associated with Unfavorable Prognosis of Canine Malignant Mammary Tumors.
Disruption of the mouse Bmal1 locus promotes heterotopic ossification with aging via TGF-beta/BMP signaling.
Metformin accelerates zebrafish heart regeneration by inducing autophagy.
Extracellular AGR2 activates neighboring fibroblasts through endocytosis and direct binding to β-catenin that requires AGR2 dimerization and adhesion domains.
Adenylyl cyclase 3 regulates osteocyte mechanotransduction and primary cilium.
Targeting MUS81 promotes the anticancer effect of WEE1 inhibitor and immune checkpoint blocking combination therapy via activating cGAS/STING signaling in gastric cancer cells.
Inhibition of immunoproteasome subunit low molecular mass polypeptide 7 with ONX-0914 improves hypoxic-ischemic brain damage via PI3K/Akt signaling.
PDCD4 Simultaneously Promotes Microglia Activation via PDCD4-MAPK-NF-κB Positive Loop and Facilitates Neuron Apoptosis During Neuroinflammation.
Thymosin beta 4 alleviates non-alcoholic fatty liver by inhibiting ferroptosis via up-regulation of GPX4.
CDC42EP3 is a key promoter involved in the development and progression of gastric cancer.
Infantile spasms-linked Nedd4-2 mediates hippocampal plasticity and learning via cofilin signaling.
Cathepsin B Regulates Mice Granulosa Cells' Apoptosis and Proliferation In Vitro.
Newcastle disease virus degrades SIRT3 via PINK1-PRKN-dependent mitophagy to reprogram energy metabolism in infected cells.
FAIM regulates autophagy through glutaminolysis in lung adenocarcinoma.
Lipophagy deficiency exacerbates ectopic lipid accumulation and tubular cells injury in diabetic nephropathy.
Jian-Pi-Yi-Shen formula enhances perindopril inhibition of chronic kidney disease progression by activation of SIRT3, modulation of mitochondrial dynamics, and antioxidant effects.
AnnexinA7 promotes epithelial-mesenchymal transition by interacting with Sorcin and contributes to aggressiveness in hepatocellular carcinoma.
CD146 as a promising therapeutic target for retinal and choroidal neovascularization diseases.
RCAN1.4 attenuates renal fibrosis through inhibiting calcineurin-mediated nuclear translocation of NFAT2.
Chitosan oligosaccharides packaged into rat adipose mesenchymal stem cells-derived extracellular vesicles facilitating cartilage injury repair and alleviating osteoarthritis.
Clonal hematopoiesis with JAK2V617F promotes pulmonary hypertension with ALK1 upregulation in lung neutrophils.
Identification of novel key genes associated with the metastasis of prostate cancer based on bioinformatics prediction and validation.
Lnc-DC promotes estrogen independent growth and tamoxifen resistance in breast cancer.
Loss of TDP-43 function underlies hippocampal and cortical synaptic deficits in TDP-43 proteinopathies.
PFOS facilitates liver inflammation and steatosis: An involvement of NLRP3 inflammasome-mediated hepatocyte pyroptosis.
Crocetin suppresses angiogenesis and metastasis through inhibiting sonic hedgehog signaling pathway in gastric cancer.
Circular RNA circUBE2J2 acts as the sponge of microRNA-370-5P to suppress hepatocellular carcinoma progression.
CHD8 safeguards early neuroectoderm differentiation in human ESCs and protects from apoptosis during neurogenesis.
cGAS guards against chromosome end-to-end fusions during mitosis and facilitates replicative senescence.
Kinesin family member 2C promotes hepatocellular carcinoma growth and metastasis via activating MEK/ERK pathway.
CD93 a potential player in cytotrophoblast and endothelial cell migration.
FGGY carbohydrate kinase domain containing is expressed and alternatively spliced in skeletal muscle and attenuates MAP kinase and Akt signaling.
FERM domain-containing protein 6 exerts a tumor-inhibiting role in thyroid cancer by antagonizing oncogenic YAP1.
TM7SF2 regulates cell proliferation and apoptosis by activation of C-Raf/ERK pathway in cervical cancer.
Protective Roles of Xijiao Dihuang Tang on Coronary Artery Injury in Kawasaki Disease.
An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.
Overexpression of FGF2 delays the progression of osteonecrosis of the femoral head activating the PI3K/Akt signaling pathway.
Palmitoylation targets the calcineurin phosphatase to the phosphatidylinositol 4-kinase complex at the plasma membrane.
Noncanonical Wnt5a signaling regulates tendon stem/progenitor cells senescence.
Human mesenchymal stem cells derived exosomes inhibit the growth of acute myeloid leukemia cells via regulating miR-23b-5p/TRIM14 pathway.
INTS6 promotes colorectal cancer progression by activating of AKT and ERK signaling.
T-lymphoma invasion and metastasis 1 promotes invadopodia formation and is regulated by the PI3K/Akt signaling pathway in hepatocellular carcinoma.
The expression of IFN-β is suppressed by the viral 3D polymerase via its impact on PGAM5 expression during enterovirus D68 infection.
Design, synthesis, and biological evaluation of 2,4-diamino pyrimidine derivatives as potent FAK inhibitors with anti-cancer and anti-angiogenesis activities.
HBeAg mediates inflammatory functions of macrophages by TLR2 contributing to hepatic fibrosis.
SMAD2 regulates testicular development and testosterone synthesis in Hu sheep.
Astaxanthin attenuates contrast-induced acute kidney injury in rats via ROS/NLRP3 inflammasome.
The FOXM1/RNF26/p57 axis regulates the cell cycle to promote the aggressiveness of bladder cancer.
Human m6A-mRNA and lncRNA epitranscriptomic microarray reveal function of RNA methylation in hemoglobin H-constant spring disease.
DLEU1 promotes oral squamous cell carcinoma progression by activating interferon-stimulated genes.
17β-Estradiol Enhances Porcine Meiosis Resumption from Autophagy-Induced Gap Junction Intercellular Communications and Connexin 43 Phosphorylation via the MEK/ERK Signaling Pathway.
The interaction of S100A16 and GRP78 actives endoplasmic reticulum stress-mediated through the IRE1α/XBP1 pathway in renal tubulointerstitial fibrosis.
MINDY1 promotes breast cancer cell proliferation by stabilizing estrogen receptor α.
Phase separation of Nur77 mediates celastrol-induced mitophagy by promoting the liquidity of p62/SQSTM1 condensates.
BRCA2 associates with MCM10 to suppress PRIMPOL-mediated repriming and single-stranded gap formation after DNA damage.
Attenuation of Activated eIF2α Signaling by ISRIB Treatment After Spinal Cord Injury Improves Locomotor Function.
Ordered assembly of the cytosolic RNA-sensing MDA5-MAVS signaling complex via binding to unanchored K63-linked poly-ubiquitin chains.
Blockade of T helper 17 cell function ameliorates recurrent Clostridioides difficile infection in mice.
Analyzing the whole-transcriptome profiles of ncRNAs and predicting the competing endogenous RNA networks in cervical cancer cell lines with cisplatin resistance.
FAM83A promotes proliferation and metastasis via Wnt/β-catenin signaling in head neck squamous cell carcinoma.
MiR-20a-5p overexpression prevented diabetic cardiomyopathy via inhibition of cardiomyocyte apoptosis, hypertrophy, fibrosis and JNK/NF-κB signalling pathway.
Vezatin regulates seizures by controlling AMPAR-mediated synaptic activity.
Inactivation of the CIC-DUX4 oncogene through P300/CBP inhibition, a therapeutic approach for CIC-DUX4 sarcoma.
ZFC3H1 prevents RNA trafficking into nuclear speckles through condensation.
PCYT2 synthesizes CDP-glycerol in mammals and reduced PCYT2 enhances the expression of functionally glycosylated α-dystroglycan.
Integrative epigenomic and high-throughput functional enhancer profiling reveals determinants of enhancer heterogeneity in gastric cancer.
Posttranscriptional inhibition of γ-adducin promotes the proliferation and migration of osteosarcoma cells.
Cigarette smoking induces aberrant N6-methyladenosine of DAPK2 to promote non-small cell lung cancer progression by activating NF-κB pathway.
Autophagy-dependent ferroptosis contributes to cisplatin-induced hearing loss.
Cold-inducible RNA-binding protein regulates cyclin B1 against spermatogenesis arrest caused by heat stress.
Hsa_circ_0011385 knockdown represses cell proliferation in hepatocellular carcinoma.
AGTR1 blocker attenuates activation of Tenon's capsule fibroblasts after glaucoma filtration surgery via the NF-κB signaling pathway.
Diabetic ferroptosis plays an important role in triggering on inflammation in diabetic wound.
Relationships between di-(2-ethylhexyl) phthalate exposure and lipid metabolism in adolescents: Human data and experimental rat model analyses.
Circ-RNF13, as an oncogene, regulates malignant progression of HBV-associated hepatocellular carcinoma cells and HBV infection through ceRNA pathway of circ-RNF13/miR-424-5p/TGIF2.
Flow cytometry allows rapid detection of protein aggregates in cellular and zebrafish models of spinocerebellar ataxia 3.
Crosstalk Between RPE Cells and Choroidal Endothelial Cells via the ANXA1/FPR2/SHP2/NLRP3 Inflammasome/Pyroptosis Axis Promotes Choroidal Neovascularization.
Elevated β-secretase 1 expression mediates CD4+ T cell dysfunction via PGE2 signalling in Alzheimer's disease.
Yiqi-Huoxue granule promotes angiogenesis of ischemic myocardium through miR-126/PI3K/Akt axis in endothelial cells.
Switch receptor T3/28 improves long-term persistence and antitumor efficacy of CAR-T cells.
Circular RNA circZFPM2 promotes epithelial-mesenchymal transition in endometriosis by regulating miR-205-5p/ZEB1 signalling pathway.
Decreased phosphorylation facilitates the degradation of the endogenous protective molecule c-Ski in vascular smooth muscle cells.
Neuroprotective effect of Na+ /H+ exchangers isoform-1 inactivation against 6-hydroxydopamine-induced mitochondrial dysfunction and neuronal apoptosis in Parkinson's disease models.
Long non-coding RNA HOXA-AS3 facilitates the malignancy in colorectal cancer by miR-4319/SPNS2 axis.
Knockdown of ST6Gal-I expression in human hepatocellular carcinoma cells inhibits their exosome-mediated proliferation- and migration-promoting effects.
SARS-CoV-2 B.1.617.2 Delta variant replication and immune evasion.
miR-221/222 suppression induced by activation of the cAMP/PKA/CREB1 pathway is required for cAMP-induced bidirectional differentiation of glioma cells.
Effect of mifepristone and lithospermum combination regimen on medical abortion in early pregnancy rats.
Dihydroartemisinin triggers ferroptosis in primary liver cancer cells by promoting and unfolded protein response‑induced upregulation of CHAC1 expression.
MiR-214-3p plays a protective role in diabetic neuropathic rats by regulating Nav1.3 and TLR4.
Silencing ACTG1 Expression Induces Prostate Cancer Epithelial Mesenchymal Transition Through MAPK/ERK Signaling Pathway.
Selenium-modified calcium phosphate cement can accelerate bone regeneration of osteoporotic bone defect.
Novel WEE2 compound heterozygous mutations identified in patients with fertilization failure or poor fertilization.
Rosamultin from Potentilla anserine L. exhibits nephroprotection and antioxidant activity by regulating the reactive oxygen species/C/EBP homologous protein signaling pathway.
Icariin attenuates renal fibrosis in chronic kidney disease by inhibiting interleukin-1β/transforming growth factor-β-mediated activation of renal fibroblasts.
Cellular hnRNPAB interacts with avian influenza viral protein PB2 and inhibits virus replication potentially by restricting PB2 mRNA nuclear export and PB2 protein level.
Environmental Pollutant Benzo[a]pyrene Upregulated Long Non-coding RNA HZ07 Inhibits Trophoblast Cell Migration by Inactivating PI3K/AKT/MMP2 Signaling Pathway in Recurrent Pregnancy Loss.
Mapping of pseudouridine residues on cellular and viral transcripts using a novel antibody-based technique.
Japanese encephalitis virus restricts HMGB1 expression to maintain MAPK pathway activation for viral replication.
Drebrin, an actin-binding protein, is required for lens morphogenesis and growth.
SC66 inhibits the proliferation and induces apoptosis of human bladder cancer cells by targeting the AKT/β-catenin pathway.
Casein Kinase II exacerbates rheumatoid arthritis via promoting Th1 and Th17 cell inflammatory responses.
miR‑486‑5p suppresses gastric cancer cell growth and migration through downregulation of fibroblast growth factor 9.
miR-106b-5p upregulation is associated with microglial activation and inflammation in the mouse hippocampus following status epilepticus.
In vivo assessment of molybdenum and cadmium co-induce nephrotoxicity via NLRP3/Caspase-1-mediated pyroptosis in ducks.
Inhibition of Dishevelled-2 suppresses the biological behavior of pancreatic cancer by downregulating Wnt/β-catenin signaling.
An integrated RNA-Seq and network study reveals that valproate inhibited progesterone production in human granulosa cells.
ML-SA1 and SN-2 inhibit endocytosed viruses through regulating TRPML channel expression and activity.
Involvement of REV-ERBα dysregulation and ferroptosis in aristolochic acid I-induced renal injury.
NEDD4 triggers FOXA1 ubiquitination and promotes colon cancer progression under microRNA-340-5p suppression and ATF1 upregulation.
Chitotriosidase attenuates brain inflammation via HDAC3/NF-κB pathway in D-galactose and aluminum-induced rat model with cognitive impairments.
B2M gene expression shapes the immune landscape of lung adenocarcinoma and determines the response to immunotherapy.
Multifunctional MnO2-based nanoplatform-induced ferroptosis and apoptosis for synergetic chemoradiotherapy.
Fragile X mental retardation protein-regulated proinflammatory cytokine expression in the spinal cord contributes to the pathogenesis of inflammatory pain induced by complete Freund's adjuvant.
Prenatal EGCG exposure-induced heart mass reduction in adult male mice and underlying mechanisms.
1,3-dichloro-2-propanol induced hepatic lipid accumulation by inhibiting autophagy via AKT/mTOR/FOXO1 pathway in mice.
Perfluorooctane sulfonate induces autophagy-dependent lysosomal membrane permeabilization by weakened interaction between tyrosinated alpha-tubulin and spinster 1.
Varied thyroid disrupting effects of perfluorooctanoic acid (PFOA) and its novel alternatives hexafluoropropylene-oxide-dimer-acid (GenX) and ammonium 4,8-dioxa-3H-perfluorononanoate (ADONA) in vitro.
αCaMKII in the lateral amygdala mediates PTSD-Like behaviors and NMDAR-Dependent LTD.
Liraglutide ameliorates diabetes-associated cognitive dysfunction via rescuing autophagic flux.
Osteopontin improves sensitivity to tyrosine kinase inhibitor in lung adenocarcinoma in vitro by promoting epidermal growth factor receptor phosphorylation.
Selenium-enriched Bifidobacterium longum DD98 attenuates irinotecan-induced intestinal and hepatic toxicity in vitro and in vivo.
Platycodon grandiflorus polysaccharides inhibit Pseudorabies virus replication via downregulating virus-induced autophagy.
Deficiency in WDFY4 reduces the number of CD8+ T cells via reactive oxygen species-induced apoptosis.
RIP1-dependent linear and nonlinear recruitments of caspase-8 and RIP3 respectively to necrosome specify distinct cell death outcomes.
Synthesis and evaluation of 3-(phenylethynyl)-1,1'-biphenyl-2-carboxylate derivatives as new HIF-1 inhibitors.
DOC-2/DAB2 interactive protein destabilizes c-Myc to impair the growth and self-renewal of colon tumor-repopulating cells.
HIF2α promotes tumour growth in clear cell renal cell carcinoma by increasing the expression of NUDT1 to reduce oxidative stress.
Ceruloplasmin overexpression is associated with oncogenic pathways and poorer survival rates in clear-cell renal cell carcinoma.
LINC00370 modulates miR-222-3p-RGS4 axis to protect against osteoporosis progression.
CD38 deficiency up-regulated IL-1β and MCP-1 through TLR4/ERK/NF-κB pathway in sepsis pulmonary injury.
Direct Activation of Endothelial Cells by SARS-CoV-2 Nucleocapsid Protein Is Blocked by Simvastatin.
Discovery of Phenolic Glycoside from Hyssopus cuspidatus Attenuates LPS-Induced Inflammatory Responses by Inhibition of iNOS and COX-2 Expression through Suppression of NF-κB Activation.
HSD17B6 downregulation predicts poor prognosis and drives tumor progression via activating Akt signaling pathway in lung adenocarcinoma.
High throughput sequencing of whole transcriptome and construct of ceRNA regulatory network in RD cells infected with enterovirus D68.
LPS-induced macrophage HMGB1-loaded extracellular vesicles trigger hepatocyte pyroptosis by activating the NLRP3 inflammasome.
Total glycosides from Eucommia ulmoides seed promoted osteogenic differentiation of adipose-derived mesenchymal stem cells and bone formation in ovariectomized rats through regulating Notch signaling pathway.
Erythromycin reduces nasal inflammation by inhibiting immunoglobulin production, attenuating mucus secretion, and modulating cytokine expression.
FAK regulates cardiomyocyte mitochondrial fission and function through Drp1.
Follicle-stimulating hormone regulates glycolysis of water buffalo follicular granulosa cells through AMPK/SIRT1 signalling pathway.
Increased expression of TAZ and associated upregulation of PD-L1 in cervical cancer.
N6-methyladenosine modification of CDH1 mRNA promotes PM2.5-induced pulmonary fibrosis via mediating epithelial mesenchymal transition.
Exogenous adenosine activates A2A adenosine receptor to inhibit RANKL-induced osteoclastogenesis via AP-1 pathway to facilitate bone repair.
GSK-3β manipulates ferroptosis sensitivity by dominating iron homeostasis.
Long non-coding RNA SNHG1 promotes fibroblast-to-myofibroblast transition during the development of pulmonary fibrosis induced by silica particles exposure.
Effect of Fc-Elabela-21 on renal ischemia/reperfusion injury in mice: Mediation of anti-apoptotic effect via Akt phosphorylation.
Taxifolin retards the D-galactose-induced aging process through inhibiting Nrf2-mediated oxidative stress and regulating the gut microbiota in mice.
Cardamonin inhibits osteogenic differentiation of human valve interstitial cells and ameliorates aortic valve calcification via interfering in the NF-κB/NLRP3 inflammasome pathway.
MICU3 regulates mitochondrial Ca2+-dependent antioxidant response in skeletal muscle aging.
SIRT1/mTOR pathway-mediated autophagy dysregulation promotes Pb-induced hepatic lipid accumulation in HepG2 cells.
Type IIB PKA is highly expressed in β cells and controls cell proliferation via regulating Cyclin D1 expression.
LAGE3 promoted cell proliferation, migration, and invasion and inhibited cell apoptosis of hepatocellular carcinoma by facilitating the JNK and ERK signaling pathway.
NEDD4L-induced ubiquitination mediating UBE2T degradation inhibits progression of lung adenocarcinoma via PI3K-AKT signaling.
Downregulation of miR-29c promotes muscle wasting by modulating the activity of leukemia inhibitory factor in lung cancer cachexia.
Bone morphogenetic protein 9 enhances osteogenic and angiogenic responses of human amniotic mesenchymal stem cells cocultured with umbilical vein endothelial cells through the PI3K/AKT/m-TOR signaling pathway.
miR-1290 promotes IL-8-mediated vascular endothelial cell adhesion by targeting GSK-3β.
Sesquiterpene Lactones from Sigesbeckia glabrescens Possessing Potent Anti-inflammatory Activity by Directly Binding to IKKα/β.
Oxidative stress transforms 3CLpro into an insoluble and more active form to promote SARS-CoV-2 replication.
Reciprocal regulation of LOXL2 and HIF1α drives the Warburg effect to support pancreatic cancer aggressiveness.
Icaritin alleviates docetaxel-induced skin injury by suppressing reactive oxygen species via estrogen receptors.
Inhibition of Ras protein activator like 2 produces antitumor effects in gastric cancer via the suppression of YAP1 activation.
Structure-Based Discovery of Potent CARM1 Inhibitors for Solid Tumor and Cancer Immunology Therapy.
The structural basis for the phospholipid remodeling by lysophosphatidylcholine acyltransferase 3.
Benzo(a)pyrene induces airway epithelial injury through Wnt5a-mediated non-canonical Wnt-YAP/TAZ signaling.
Urinary peptidomics reveals proteases involved in idiopathic membranous nephropathy.
miR-30b-5p inhibits proliferation, invasion, and migration of papillary thyroid cancer by targeting GALNT7 via the EGFR/PI3K/AKT pathway.
4D-quantitative proteomics signature of asthenozoospermia and identification of extracellular matrix protein 1 as a novel biomarker for sperm motility.
Naturally occurring UBIAD1 mutations differentially affect menaquinone biosynthesis and vitamin K-dependent carboxylation.
METTL3/14 and IL-17 signaling contribute to CEBPA-DT enhanced oral cancer cisplatin resistance.
circRNAome profiling reveals circFgfr2 regulates myogenesis and muscle regeneration via a feedback loop.
Extracellular vesicles derived from hypoxia-preconditioned olfactory mucosa mesenchymal stem cells enhance angiogenesis via miR-612.
Cadmium attenuates testosterone synthesis by promoting ferroptosis and blocking autophagosome-lysosome fusion.
IRF3-binding lncRNA-ISIR strengthens interferon production in viral infection and autoinflammation.
Blood-Based Epigenetic Markers of FKBP5 Gene Methylation in Patients With Dilated Cardiomyopathy.
MiR-15a-3p regulates ferroptosis via targeting glutathione peroxidase GPX4 in colorectal cancer.
The Y14-p53 regulatory circuit in megakaryocyte differentiation and thrombocytopenia.
Capping protein regulates endosomal trafficking by controlling F-actin density around endocytic vesicles and recruiting RAB5 effectors.
TBHQ attenuates ferroptosis against 5-fluorouracil-induced intestinal epithelial cell injury and intestinal mucositis via activation of Nrf2.
Indole-3-Propionic Acid, a Functional Metabolite of Clostridium sporogenes, Promotes Muscle Tissue Development and Reduces Muscle Cell Inflammation.
Inhibition of DTYMK significantly restrains the growth of HCC and increases sensitivity to oxaliplatin.
Identification of proximal SUMO-dependent interactors using SUMO-ID.
Shikonin Induced Program Cell Death through Generation of Reactive Oxygen Species in Renal Cancer Cells.
Downregulation of FAPP2 gene induces cell autophagy and inhibits PI3K/AKT/mTOR pathway in T-cell acute lymphoblastic leukemia.
Fluoride Stimulates Anxiety- and Depression-like Behaviors Associated with SIK2-CRTC1 Signaling Dysfunction.
Dendrobium officinale Polysaccharide Alleviates Intestinal Inflammation by Promoting Small Extracellular Vesicle Packaging of miR-433-3p.
Knockdown of circFOXO3 ameliorates cigarette smoke-induced lung injury in mice.
AKT1/HK2 Axis-mediated Glucose Metabolism: A Novel Therapeutic Target of Sulforaphane in Bladder Cancer.
Aloe-emodin derivative produces anti-atherosclerosis effect by reinforcing AMBRA1-mediated endothelial autophagy.
Knockout of mafba Causes Inner-Ear Developmental Defects in Zebrafish via the Impairment of Proliferation and Differentiation of Ionocyte Progenitor Cells.
Inhibition of DCLK1 with DCLK1-IN-1 Suppresses Renal Cell Carcinoma Invasion and Stemness and Promotes Cytotoxic T-Cell-Mediated Anti-Tumor Immunity.
Ciliary Type III Adenylyl Cyclase in the VMH Is Crucial for High-Fat Diet-Induced Obesity Mediated by Autophagy.
Smoking-associated upregulation of CBX3 suppresses ARHGAP24 expression to activate Rac1 signaling and promote tumor progression in lung adenocarcinoma.
Remodelling of gut microbiota by Berberine attenuates trimethylamine N-oxide-induced platelet hyperreaction and thrombus formation.
STOML2 interacts with PHB through activating MAPK signaling pathway to promote colorectal Cancer proliferation.
Babao Dan is a robust anti-tumor agent via inhibiting wnt/β-catenin activation and cancer cell stemness.
(-)-Epigallocatechin-3-gallate mitigates cyclophosphamide-induced intestinal injury by modulating the tight junctions, inflammation and dysbiosis in mice.
SARS-CoV-2 inhibits induction of the MHC class I pathway by targeting the STAT1-IRF1-NLRC5 axis.
Inhibition of METTL3/m6A/miR126 promotes the migration and invasion of endometrial stromal cells in endometriosis†.
PRMT1-mediated EZH2 methylation promotes breast cancer cell proliferation and tumorigenesis.
TM9SF4 is a novel regulator in lineage commitment of bone marrow mesenchymal stem cells to either osteoblasts or adipocytes.
Discovery of a Dual Tubulin and Poly(ADP-Ribose) Polymerase-1 Inhibitor by Structure-Based Pharmacophore Modeling, Virtual Screening, Molecular Docking, and Biological Evaluation.
The Large GTPase, GBP-2, Regulates Rho Family GTPases to Inhibit Migration and Invadosome Formation in Breast Cancer Cells.
Deletion of miR-15a inhibited glioma development via targeting Smad7 and inhibiting EMT pathway.
Resveratrol induces proliferation in preosteoblast cell MC3T3-E1 via GATA-1 activating autophagy.
Lipid droplets are beneficial for rabies virus replication by facilitating viral budding.
Mof acetyltransferase inhibition ameliorates glucose intolerance and islet dysfunction of type 2 diabetes via targeting pancreatic α-cells.
Isorhapontigenin (ISO) inhibits EMT through FOXO3A/METTL14/VIMENTIN pathway in bladder cancer cells.
Sodium cantharidate induces Apoptosis in breast cancer cells by regulating energy metabolism via the protein phosphatase 5-p53 axis.
Neurotoxicity of a pyrethroid pesticide deltamethrin is associated with the imbalance in proteolytic systems caused by mitophagy activation and proteasome inhibition.
Comparative analysis of the MyTH4-FERM myosins reveals insights into the determinants of actin track selection in polarized epithelia.
Muse Cells Have Higher Stress Tolerance than Adipose Stem Cells due to the Overexpression of the CCNA2 Gene.
A novel mutation in NF1 gene of patient with Neurofibromatosis type 1: A case report and functional study.
Trojan Horse Delivery of 4,4'-Dimethoxychalcone for Parkinsonian Neuroprotection.
Aldehyde Dehydrogenase 2 Mediates Alcohol-Induced Colorectal Cancer Immune Escape through Stabilizing PD-L1 Expression.
Elevated type I interferon responses potentiate metabolic dysfunction, inflammation, and accelerated aging in mtDNA mutator mice.
Centrosomal protein FOR20 knockout mice display embryonic lethality and left-right patterning defects.
The Long Noncoding RNA Hepatocyte Nuclear Factor 4α Antisense RNA 1 Negatively Regulates Cytochrome P450 Enzymes in Huh7 Cells via Histone Modifications.
MiR-195-5p inhibits proliferation and invasion of nerve cells in Hirschsprung disease by targeting GFRA4.
TGIF1 plays a carcinogenic role in esophageal squamous cell carcinoma through the Wnt/β‑catenin and Akt/mTOR signaling pathways.
LINC01816 promotes the migration, invasion and epithelial‑mesenchymal transition of thyroid carcinoma cells by sponging miR‑34c‑5p and regulating CRABP2 expression levels.
Methylation gene KCNC1 is associated with overall survival in patients with seminoma.
Novel gene-encoded intermolecular FRET sensor for tracking glycosylation of CD147 in living cells.
Relevance of CYP3A5 Expression on the Clinical Outcome of Patients With Renal Cell Carcinoma.
Acetaldehyde Dehydrogenase 2 regulates HMG-CoA reductase stability and cholesterol synthesis in the liver.
Long non-coding RNA SMASR inhibits the EMT by negatively regulating TGF-β/Smad signaling pathway in lung cancer.
Antiangiogenic effect of arsenic trioxide in HUVECs by FoxO3a-regulated autophagy.
Glucose-dependent insulinotropic polypeptide modifies adipose plasticity and promotes beige adipogenesis of human omental adipose-derived stem cells.
L-leucine promotes axonal outgrowth and regeneration via mTOR activation.
TUFM is involved in Alzheimer's disease-like pathologies that are associated with ROS.
BALB/c mice infected with Angiostrongylus cantonensis: A new model for demyelination in the brain.
Porcine TRIM21 RING-finger E3 ubiquitin ligase is essential for anti-PRRSV activity.
RAGE: A potential therapeutic target during FGF1 treatment of diabetes-mediated liver injury.
Zebrafish hhatla is involved in cardiac hypertrophy.
Podocyte apoptosis in diabetic nephropathy by BASP1 activation of the p53 pathway via WT1.
LIMIT is an immunogenic lncRNA in cancer immunity and immunotherapy.
Exosomal microRNA-301a-3p promotes the proliferation and invasion of nasopharyngeal carcinoma cells by targeting BTG1 mRNA.
Regulatory role of the TLR4/JNK signaling pathway in sepsis‑induced myocardial dysfunction.
Protective effects of curcumin against rat intestinal inflammation‑related motility disorders.
The DpdtbA induced EMT inhibition in gastric cancer cell lines was through ferritinophagy-mediated activation of p53 and PHD2/hif-1α pathway.
Role of vasodilator-stimulated phosphoprotein in RANKL-differentiated murine macrophage RAW264.7 cells: Modulation of NF-κB, c-Fos and NFATc1 transcription factors.
Synergistic effects of olaparib combined with ERCC1 on the sensitivity of cisplatin in non-small cell lung cancer.
Promoting roles of KLF5 in myocardial infarction in mice involving microRNA-27a suppression and the following GFPT2/TGF-β/Smad2/3 axis activation.
Gut-Lung Dysbiosis Accompanied by Diabetes Mellitus Leads to Pulmonary Fibrotic Change through the NF-κB Signaling Pathway.
Integrated transcriptomics and epigenomics reveal chamber-specific and species-specific characteristics of human and mouse hearts.
Knockdown of the mRNA encoding the ribosomal protein eL38 in mammalian cells causes a substantial reorganization of genomic transcription.
Mitochondrial TXN2 attenuates amyloidogenesis via selective inhibition of BACE1 expression.
α-synuclein abnormalities trigger focal tau pathology, spreading to various brain areas in Parkinson disease.
Toxicological and physiological effects of successive exposure to ochratoxin A at food regulatory limits.
Identification of differentially expressed proteins between fused and open sutures in sagittal nonsyndromic craniosynostosis during suture development by quantitative proteomic analysis.
Qingjie Fuzheng Granule suppresses lymphangiogenesis in colorectal cancer via the VEGF-C/VEGFR-3 dependent PI3K/AKT pathway.
The Kidney-Related Effects of Polystyrene Microplastics on Human Kidney Proximal Tubular Epithelial Cells HK-2 and Male C57BL/6 Mice.
The clinical significance, prognostic value and biological role of lncRNA LINC01793 in oral squamous cell carcinoma.
Tracing production instability in a clonally derived CHO cell line using single-cell transcriptomics.
The critical role of ZP genes in female infertility characterized by empty follicle syndrome and oocyte degeneration.
SMYD3-PARP16 axis accelerates unfolded protein response and mediates neointima formation.
miR-140-3p inhibits colorectal cancer progression and its liver metastasis by targeting BCL9 and BCL2.
The near-infrared dye IR-61 restores erectile function in a streptozotocin-induced diabetes model via mitochondrial protection.
G-Protein-coupled Estrogen Receptor 1 Agonist G-1 Perturbs Sunitinib Resistance-related Phosphoproteomic Signatures in Renal Cell Carcinoma.
Silencing TAK1 reduces MAPKs-MMP2/9 expression to reduce inflammation-driven neurohistological disruption post spinal cord injury.
BCL7C suppresses ovarian cancer growth by inactivating mutant p53.
Time-resolved proteomics profiling of the ciliary Hedgehog response.
miR-132 mediates cell permeability and migration by targeting occludin in high-glucose -induced ARPE-19 cells.
Neocortex- and hippocampus-specific deletion of Gabrg2 causes temperature-dependent seizures in mice.
Vertebrate cells differentially interpret ciliary and extraciliary cAMP.
Mitocytosis, a migrasome-mediated mitochondrial quality-control process.
SEC61G promotes breast cancer development and metastasis via modulating glycolysis and is transcriptionally regulated by E2F1.
Protective Effects of Fucoxanthin on Hydrogen Peroxide-Induced Calcification of Heart Valve Interstitial Cells.
The SUN1-SPDYA interaction plays an essential role in meiosis prophase I.
STIP1 knockdown suppresses colorectal cancer cell proliferation, migration and invasion by inhibiting STAT3 pathway.
circ-PTK2 (hsa_circ_0008305) regulates the pathogenic processes of ovarian cancer via miR-639 and FOXC1 regulatory cascade.
Activation of the STAT3 Signaling Pathway by the RNA-Dependent RNA Polymerase Protein of Arenavirus.
OTUD7B stabilizes estrogen receptor α and promotes breast cancer cell proliferation.
Splicing factor SRSF6 mediates pleural fibrosis.
The viral restriction factor tetherin/BST2 tethers cytokinetic midbody remnants to the cell surface.
Downregulation of CD151 restricts VCAM-1 mediated leukocyte infiltration to reduce neurobiological injuries after experimental stroke.
miR-338-3p inhibits autophagy in a rat model of allergic rhinitis after PM2.5 exposure through AKT/mTOR signaling by targeting UBE2Q1.
Long non-coding RNA SNHG14 aggravates LPS-induced acute kidney injury through regulating miR-495-3p/HIPK1.
SAA1/TLR2 axis directs chemotactic migration of hepatic stellate cells responding to injury.
Amphiphysin I cleavage by asparagine endopeptidase leads to tau hyperphosphorylation and synaptic dysfunction.
LncRNA CD27-AS1 promotes acute myeloid leukemia progression through the miR-224-5p/PBX3 signaling circuit.
Heme cytotoxicity is the consequence of endoplasmic reticulum stress in atherosclerotic plaque progression.
LncRNA ZNF674-AS1 regulates granulosa cell glycolysis and proliferation by interacting with ALDOA.
YTHDF1 Promotes Gastric Carcinogenesis by Controlling Translation of FZD7.
BMI1 regulates multiple myeloma-associated macrophage's pro-myeloma functions.
Asenapine maleate inhibits angiotensin II-induced proliferation and activation of cardiac fibroblasts via the ROS/TGFβ1/MAPK signaling pathway.
Ferritin disorder in the plasma and hippocampus associated with major depressive disorder.
Hyperactivation of HER2-SHCBP1-PLK1 axis promotes tumor cell mitosis and impairs trastuzumab sensitivity to gastric cancer.
Endothelial genetic deletion of CD147 induces changes in the dual function of the blood-brain barrier and is implicated in Alzheimer's disease.
Interactions between Autophagy, Proinflammatory Cytokines, and Apoptosis in Neuropathic Pain: Granulocyte Colony Stimulating Factor as a Multipotent Therapy in Rats with Chronic Constriction Injury.
Antifungal Activity of Quinofumelin against Fusarium graminearum and Its Inhibitory Effect on DON Biosynthesis.
Zuojin Pill ameliorates chronic atrophic gastritis induced by MNNG through TGF-β1/PI3K/Akt axis.
Tryptanthrin Regulates Vascular Smooth Muscle Cell Phenotypic Switching in Atherosclerosis by AMP-Activated Protein Kinase/Acetyl-CoA Carboxylase Signaling Pathway.
LRRC4 functions as a neuron-protective role in experimental autoimmune encephalomyelitis.
Psoralidin, a major component of Psoraleae Fructus, induces inflammasome activation and idiosyncratic liver injury.
Hypoxia enhances the production and antitumor effect of exosomes derived from natural killer cells.
Arginine methyltransferase PRMT5 negatively regulates cGAS-mediated antiviral immune response.
The cryo-EM structure of an ERAD protein channel formed by tetrameric human Derlin-1.
Decreased miR-214-3p activates NF-κB pathway and aggravates osteoarthritis progression.
Total flavone extract from Ampelopsis megalophylla induces apoptosis in the MCF‑7 cell line.
Biological testing of chitosan-collagen-based porous scaffolds loaded with PLGA/Triamcinolone microspheres for ameliorating endoscopic dissection-related stenosis in oesophagus.
Sirtuin 1 ameliorates defenestration in hepatic sinusoidal endothelial cells during liver fibrosis via inhibiting stress-induced premature senescence.
miR‑106b‑5p targeting SIX1 inhibits TGF‑β1‑induced pulmonary fibrosis and epithelial‑mesenchymal transition in asthma through regulation of E2F1.
VSP‑17 suppresses the migration and invasion of triple‑negative breast cancer cells through inhibition of the EMT process via the PPARγ/AMPK signaling pathway.
Nucleolar and spindle‑associated protein 1 promotes non‑small cell lung cancer progression and serves as an effector of myocyte enhancer factor 2D.
20(S)-ginsenoside Rh2 induces caspase-dependent promyelocytic leukemia-retinoic acid receptor A degradation in NB4 cells via Akt/Bax/caspase9 and TNF-α/caspase8 signaling cascades.
Abnormal cGMP-dependent protein kinase I-mediated decidualization in preeclampsia.
KLF4 initiates sustained YAP activation to promote renal fibrosis in mice after ischemia-reperfusion kidney injury.
miR-30a-5p Inhibits Epithelial-to-Mesenchymal Transition by Targeting CDK6 in Nasal Polyps.
Oncogenic AURKA-enhanced N6-methyladenosine modification increases DROSHA mRNA stability to transactivate STC1 in breast cancer stem-like cells.
NFAT Overexpression Correlates with CA72-4 and Poor Prognosis of Ovarian Clear-Cell Carcinoma Subtype.
TRF2 recruits nucleolar protein TCOF1 to coordinate telomere transcription and replication.
Histone deacetylase 3 aberration inhibits Klotho transcription and promotes renal fibrosis.
Chondrocyte ferroptosis contribute to the progression of osteoarthritis.
Gambogic acid ameliorates high glucose- and palmitic acid-induced inflammatory response in ARPE-19 cells via activating Nrf2 signaling pathway: ex vivo.
AIMP3 inhibits cell growth and metastasis of lung adenocarcinoma through activating a miR-96-5p-AIMP3-p53 axis.
CRKL promotes hepatocarcinoma through enhancing glucose metabolism of cancer cells via activating PI3K/Akt.
P53 regulation of osteoblast differentiation is mediated through specific microRNAs.
SHARPIN stabilizes β-catenin through a linear ubiquitination-independent manner to support gastric tumorigenesis.
α5-nAChR and survivin: Two potential biological targets in lung adenocarcinoma.
Zenglv Fumai Granule protects cardiomyocytes against hypoxia/reoxygenation-induced apoptosis via inhibiting TRIM28 expression.
Genetic response to low‑intensity ultrasound on mouse ST2 bone marrow stromal cells.
Emodin enhances cisplatin sensitivity in non-small cell lung cancer through Pgp downregulation.
Decreased Expression of Heat Shock Protein 47 Is Associated with T-2 Toxin and Low Selenium-Induced Matrix Degradation in Cartilages of Kashin-Beck Disease.
Two loss-of-function ANKRD11 variants in Chinese patients with short stature and a possible molecular pathway.
Nuciferine protects against folic acid-induced acute kidney injury by inhibiting ferroptosis.
JMJD6 negatively regulates cytosolic RNA induced antiviral signaling by recruiting RNF5 to promote activated IRF3 K48 ubiquitination.
CITED4 mediates proliferation, apoptosis and steroidogenesis of Hu sheep granulosa cells in vitro.
Babao Dan improves neurocognitive function by inhibiting inflammation in clinical minimal hepatic encephalopathy.
DZNep attenuates allergic airway inflammation in an ovalbumin-induced murine model.
Radiotherapy programs neutrophils to an antitumor phenotype by inducing mesenchymal-epithelial transition.
Plumbagin, a Biomolecule with (Anti)Osteoclastic Properties.
Identification of Overexpressed Genes in Malignant Pleural Mesothelioma.
Epigenetically modulated miR-1224 suppresses the proliferation of HCC through CREB-mediated activation of YAP signaling pathway.
Circular RNA RBPMS inhibits bladder cancer progression via miR-330-3p/RAI2 regulation.
Long noncoding RNA SMUL suppresses SMURF2 production-mediated muscle atrophy via nonsense-mediated mRNA decay.
Design, synthesis and pharmacological evaluation of bicyclic and tetracyclic pyridopyrimidinone analogues as new KRASG12C inhibitors.
miR-98-5p protects against cerebral ischemia/reperfusion injury through anti-apoptosis and anti-oxidative stress in mice.
Hepatic HuR protects against the pathogenesis of non-alcoholic fatty liver disease by targeting PTEN.
Normalizing hyperactivity of the Gunn rat with bilirubin-induced neurological disorders via ketanserin.
HIF-1/AKT Signaling-Activated PFKFB2 Alleviates Cardiac Dysfunction and Cardiomyocyte Apoptosis in Response to Hypoxia.
Involvement of HECTD1 in LPS-induced astrocyte activation via σ-1R-JNK/p38-FOXJ2 axis.
Interaction of NEP with G Protein Pathway Suppressor 2 Facilitates Influenza A Virus Replication by Weakening the Inhibition of GPS2 to RNA Synthesis and Ribonucleoprotein Assembly.
LMNB2 promotes the progression of colorectal cancer by silencing p21 expression.
Let-7i-5p enhances cell proliferation, migration and invasion of ccRCC by targeting HABP4.
Parkinson's Disease Causative Mutation in Vps35 Disturbs Tetherin Trafficking to Cell Surfaces and Facilitates Virus Spread.
Metabolomics analysis delineates the therapeutic effects of Huangqi decoction and astragalosides on α-naphthylisothiocyanate (ANIT) -induced cholestasis in rats.
Crocetin ameliorates chronic restraint stress-induced depression-like behaviors in mice by regulating MEK/ERK pathways and gut microbiota.
NMR-Based Metabolomic Analysis for the Effects of α-Ketoglutarate Supplementation on C2C12 Myoblasts in Different Energy States.
Membrane-cytoplasm translocation of annexin A4 is involved in the metastasis of colorectal carcinoma.
Acoustic Droplet Vitrification Method for High-Efficiency Preservation of Rare Cells.
CircRNA RSF1 regulated ox-LDL induced vascular endothelial cells proliferation, apoptosis and inflammation through modulating miR-135b-5p/HDAC1 axis in atherosclerosis.
Tanshinone IIA combined with CsA inhibit myocardial cell apoptosis induced by renal ischemia-reperfusion injury in obese rats.
VPS34 regulates dynamin to determine the endocytosis of mitochondria-targeted zinc oxide nanoparticles in human osteosarcoma cells.
Identification of HOXA10 target genes in human endometrial stromal cells by RNA-seq analysis.
Clostridium Butyricum ZJU-F1 Benefits the Intestinal Barrier Function and Immune Response Associated with Its Modulation of Gut Microbiota in Weaned Piglets.
TagBiFC technique allows long-term single-molecule tracking of protein-protein interactions in living cells.
HDAC11 inhibition disrupts porcine oocyte meiosis via regulating α-tubulin acetylation and histone modifications.
CircSPI1 acts as an oncogene in acute myeloid leukemia through antagonizing SPI1 and interacting with microRNAs.
The MEK1/2 Pathway as a Therapeutic Target in High-Grade Serous Ovarian Carcinoma.
E3 Ubiquitin Ligase ASB17 Promotes Apoptosis by Ubiquitylating and Degrading BCLW and MCL1.
Kaempferol Reverses Aerobic Glycolysis via miR-339-5p-Mediated PKM Alternative Splicing in Colon Cancer Cells.
TMEM119 facilitates ovarian cancer cell proliferation, invasion, and migration via the PDGFRB/PI3K/AKT signaling pathway.
Rab26 suppresses migration and invasion of breast cancer cells through mediating autophagic degradation of phosphorylated Src.
Astrocytic ApoE reprograms neuronal cholesterol metabolism and histone-acetylation-mediated memory.
TBC1D16 predicts chemosensitivity and prognosis in adult acute myeloid leukemia (AML) patients.
GR/NF-κB signaling pathway regulates hippocampal inflammatory responses in diabetic rats with chronic unpredictable mild stress.
PDX models reflect the proteome landscape of pediatric acute lymphoblastic leukemia but divert in select pathways.
Thrombin inhibitor argatroban modulates bone marrow stromal cells behaviors and promotes osteogenesis through canonical Wnt signaling.
Identification and functional analysis of senescence-associated secretory phenotype of premature senescent hepatocytes induced by hexavalent chromium.
The role of Se content in improving anti-tumor activities and its potential mechanism for selenized Artemisia sphaerocephala polysaccharides.
MiR-1290 promotes myoblast differentiation and protects against myotube atrophy via Akt/p70/FoxO3 pathway regulation.
Perilipin 5 ameliorates high-glucose-induced podocyte injury via Akt/GSK-3β/Nrf2-mediated suppression of apoptosis, oxidative stress, and inflammation.
Citrus Alkaline Extracts Inhibit Senescence of A549 Cells to Alleviate Pulmonary Fibrosis via the β-Catenin/P53 Pathway.
Lnc13728 facilitates human mesenchymal stem cell adipogenic differentiation via positive regulation of ZBED3 and downregulation of the WNT/β-catenin pathway.
Novel IMB16-4 Compound Loaded into Silica Nanoparticles Exhibits Enhanced Oral Bioavailability and Increased Anti-Liver Fibrosis In Vitro.
SRP54 mutations induce congenital neutropenia via dominant-negative effects on XBP1 splicing.
Isoliquiritigenin Reverses Epithelial-Mesenchymal Transition Through Modulation of the TGF-β/Smad Signaling Pathway in Endometrial Cancer.
MAGI1 inhibits the AMOTL2/p38 stress pathway and prevents luminal breast tumorigenesis.
The role of irreversible electroporation in promoting M1 macrophage polarization via regulating the HMGB1-RAGE-MAPK axis in pancreatic cancer.
The LncRNA RP11-301G19.1/miR-582-5p/HMGB2 axis modulates the proliferation and apoptosis of multiple myeloma cancer cells via the PI3K/AKT signalling pathway.
Positive regulation of Type III secretion effectors and virulence by RyhB paralogs in Salmonella enterica serovar Enteritidis.
Downregulation of lncRNA ZNF582-AS1 due to DNA hypermethylation promotes clear cell renal cell carcinoma growth and metastasis by regulating the N(6)-methyladenosine modification of MT-RNR1.
Endogenous conversion of n-6 to n-3 polyunsaturated fatty acids facilitates the repair of cardiotoxin-induced skeletal muscle injury in fat-1 mice.
Long Noncoding RNA DUXAP8 Promotes Pancreatic Carcinoma Cell Migration and Invasion Via Pathway by miR-448/WTAP/Fak Signaling Axis.
TMEM2 binds to CSNK2A3 to inhibit HBV infection via activation of the JAK/STAT pathway.
Cancer-associated fibroblasts promote the survival of irradiated nasopharyngeal carcinoma cells via the NF-κB pathway.
Prematurity blunts the insulin- and amino acid-induced stimulation of translation initiation and protein synthesis in skeletal muscle of neonatal pigs.
Endoplasmic Reticulum Stress-Mediated p62 Downregulation Inhibits Apoptosis via c-Jun Upregulation.
Contributions of HO-1-Dependent MAPK to Regulating Intestinal Barrier Disruption.
Cadmium and molybdenum co-induce pyroptosis via ROS/PTEN/PI3K/AKT axis in duck renal tubular epithelial cells.
Tubeimoside I promotes angiogenesis via activation of eNOS-VEGF signaling pathway.
Benzo[a]pyrene induces fibrotic changes and impairs differentiation in lung stem cells.
Circulating Exosomes From Patients With Graves' Disease Induce an Inflammatory Immune Response.
METTL3-mediated m6A modification regulates cell cycle progression of dental pulp stem cells.
Iguratimod-encapsulating PLGA-NPs induce human multiple myeloma cell death via reactive oxygen species and Caspase-dependent signalling.
Tumor protein D52 promotes breast cancer proliferation and migration via the long non-coding RNA NEAT1/microRNA-218-5p axis.
Overexpression of lipoic acid synthase gene alleviates diabetic nephropathy of Leprdb/db mice.
Vitexin exerts protective effects against calcium oxalate crystal-induced kidney pyroptosis in vivo and in vitro.
PFKP facilitates ATG4B phosphorylation during amino acid deprivation-induced autophagy.
Suberoylanilide Hydroxamic Acid (SAHA) Reduces Fibrosis Markers and Deactivates Human Stellate Cells via the Epithelial-Mesenchymal Transition (EMT).
Human SND2 mediates ER targeting of GPI-anchored proteins with low hydrophobic GPI attachment signals.
A phase-separated nuclear GBPL circuit controls immunity in plants.
Carbon monoxide alleviates senescence in diabetic nephropathy by improving autophagy.
Attenuation of the upregulation of NF‑κB and AP‑1 DNA‑binding activities induced by tunicamycin or hypoxia/reoxygenation in neonatal rat cardiomyocytes by SERCA2a overexpression.
Long non‑coding RNA MIR4435‑2HG promotes the progression of head and neck squamous cell carcinoma by regulating the miR‑383‑5p/RBM3 axis.
Differentially expressed proteins identified by TMT proteomics analysis in children with verrucous epidermal naevi.
Mutual dependency between lncRNA LETN and protein NPM1 in controlling the nucleolar structure and functions sustaining cell proliferation.
Generation and identification of endothelial-specific Hrh2 knockout mice.
Comprehensive interactome analysis of the spike protein of swine acute diarrhea syndrome coronavirus.
Targeting IDH1/2 mutant cancers with combinations of ATR and PARP inhibitors.
Matrix stiffness-mediated effects on macrophages polarization and their LOXL2 expression.
Lipotoxicity suppresses the synthesis of growth hormone in pituitary somatotrophs via endoplasmic reticulum stress.
Rescue of maternal immune activation-induced behavioral abnormalities in adult mouse offspring by pathogen-activated maternal Treg cells.
Crosstalk between the COX2-PGE2-EP4 signaling pathway and primary cilia in osteoblasts after mechanical stimulation.
Acvr1 deletion in osteoblasts impaired mandibular bone mass through compromised osteoblast differentiation and enhanced sRANKL-induced osteoclastogenesis.
SOD3 deficiency induces liver fibrosis by promoting hepatic stellate cell activation and epithelial-mesenchymal transition.
Dioscin inhibits SCC15 cell proliferation via the RASSF1A/MST2/YAP axis.
SEC61G is upregulated and required for tumor progression in human kidney cancer.
Salidroside overcomes dexamethasone resistance in T-acute lymphoblastic leukemia cells.
Ginkgo biloba delays light-induced photoreceptor degeneration through antioxidant and antiapoptotic properties.
Oncogenic WIP1 phosphatase attenuates the DNA damage response and sensitizes p53 mutant Jurkat cells to apoptosis.
PHD Finger Protein 19 Promotes Cardiac Hypertrophy via Epigenetically Regulating SIRT2.
DEK is highly expressed in breast cancer and is associated with malignant phenotype and progression.
Long noncoding RNA PM maintains cerebellar synaptic integrity and Cbln1 activation via Pax6/Mll1-mediated H3K4me3.
Ketoplatin in triple-negative breast cancer cells MDA-MB-231: High efficacy and low toxicity, and positive impact on inflammatory microenvironment.
Virus-inducible IGFALS facilitates innate immune responses by mediating IRAK1 and TRAF6 activation.
T-17, a spirostanol saponin, inhibits p53-independent proliferation and p53-dependent migration of gastric cancer cells.
SNX-3 mediates retromer-independent tubular endosomal recycling by opposing EEA-1-facilitated trafficking.
NIR-II Absorbing Semiconducting Polymer-Triggered Gene-Directed Enzyme Prodrug Therapy for Cancer Treatment.
PPARα agonist WY-14,643 enhances ethanol metabolism in mice: Role of catalase.
Paricalcitol inhibits oxidative stress-induced cell senescence of the bile duct epithelium dependent on modulating Sirt1 pathway in cholestatic mice.
Unbiased proteomic screening identifies a novel role for the E3 ubiquitin ligase Nedd4-2 in translational suppression during ER stress.
ALS-causing SOD1 mutants regulate occludin phosphorylation/ubiquitination and endocytic trafficking via the ITCH/Eps15/Rab5 axis.
Prohibitin regulates mTOR pathway via interaction with FKBP8.
AMD3465 (hexahydrobromide) rescues the MG63 osteoblasts against the apoptosis induced by high glucose.
Gu-Ben-Fang-Xiao decoction modulates lipid metabolism by activating the AMPK pathway in asthma remission.
Nuclear m6A reader YTHDC1 regulates the scaffold function of LINE1 RNA in mouse ESCs and early embryos.
Design, synthesis and biological evaluation of anilide (dicarboxylic acid) shikonin esters as antitumor agents through targeting PI3K/Akt/mTOR signaling pathway.
C/EBPδ drives key endocrine signals in the human amnion at parturition.
HYD-PEP06 suppresses hepatocellular carcinoma metastasis, epithelial-mesenchymal transition and cancer stem cell-like properties by inhibiting PI3K/AKT and WNT/β-catenin signaling activation.
Metformin Carbon Dots for Promoting Periodontal Bone Regeneration via Activation of ERK/AMPK Pathway.
PARP inhibitors promote stromal fibroblast activation by enhancing CCL5 autocrine signaling in ovarian cancer.
CircC16orf62 promotes hepatocellular carcinoma progression through the miR-138-5p/PTK2/AKT axis.
SARS-CoV-2 exacerbates proinflammatory responses in myeloid cells through C-type lectin receptors and Tweety family member 2.
Attenuation by HSP90 inhibitors of EGF-elicited migration of osteoblasts: involvement of p44/p42 MAP kinase.
SNP rs10420324 in the AMPA receptor auxiliary subunit TARP γ-8 regulates the susceptibility to antisocial personality disorder.
Chronic exposure to PFO4DA and PFO5DoDA, two perfluoroalkyl ether carboxylic acids (PFECAs), suppresses hepatic stress signals and disturbs glucose and lipid metabolism in male mice.
The functional characterization of phosphorylation of tristetraprolin at C-terminal NOT1-binding domain.
Gankyrin activates the hedgehog signalling to drive metastasis in osteosarcoma.
Design, synthesis, and neuroprotective effects of novel hybrid compounds containing edaravone analogue and 3-n-butylphthalide ring-opened derivatives.
Protective effects of prucalopride in MPTP-induced Parkinson's disease mice: Neurochemistry, motor function and gut barrier.
Matrine suppresses cell growth of diffuse large B-cell lymphoma via inhibiting CaMKIIγ/c-Myc/CDK6 signaling pathway.
YTHDF1 promotes hepatocellular carcinoma progression via activating PI3K/AKT/mTOR signaling pathway and inducing epithelial-mesenchymal transition.
Formin-like protein 2 promotes cell proliferation by a p27-related mechanism in human breast cancer cells.
Self-stabilizing regulation of deubiquitinating enzymes in an enzymatic activity-dependent manner.
The lipid-lowering drug fenofibrate combined with si-HOTAIR can effectively inhibit the proliferation of gliomas.
IL-37b alleviates endothelial cell apoptosis and inflammation in Kawasaki disease through IL-1R8 pathway.
The CTNNBIP1-CLSTN1 fusion transcript regulates human neocortical development.
HCP5, as the sponge of miR-1291, facilitates AML cell proliferation and restrains apoptosis via increasing PIK3R5 expression.
Trim21-mediated HIF-1α degradation attenuates aerobic glycolysis to inhibit renal cancer tumorigenesis and metastasis.
A network-based analysis and experimental validation of traditional Chinese medicine Yuanhu Zhitong Formula in treating neuropathic pain.
Ginsenoside Rh2 alleviates ulcerative colitis by regulating the STAT3/miR-214 signaling pathway.
Smek1 deficiency exacerbates experimental autoimmune encephalomyelitis by activating proinflammatory microglia and suppressing the IDO1-AhR pathway.
The Anti-Tumor Effect and Underlying Apoptotic Mechanism of Ginsenoside Rk1 and Rg5 in Human Liver Cancer Cells.
Follicle-stimulating hormone worsens osteoarthritis by causing inflammation and chondrocyte dedifferentiation.
An integrative transcriptome study reveals Ddit4/Redd1 as a key regulator of cancer cachexia in rodent models.
NOL4L, a novel nuclear protein, promotes cell proliferation and metastasis by enhancing the PI3K/AKT pathway in ovarian cancer.
Circ3823 contributes to growth, metastasis and angiogenesis of colorectal cancer: involvement of miR-30c-5p/TCF7 axis.
SNAT2/SLC38A2 Confers the Stemness of Gastric Cancer Cells via Regulating Glutamine Level.
A knockout cell library of GPI biosynthetic genes for functional studies of GPI-anchored proteins.
Ferryl Hemoglobin and Heme Induce A1-Microglobulin in Hemorrhaged Atherosclerotic Lesions with Inhibitory Function against Hemoglobin and Lipid Oxidation.
Tissue- and stage-specific landscape of the mouse translatome.
m6A RNA hypermethylation-induced BACE2 boosts intracellular calcium release and accelerates tumorigenesis of ocular melanoma.
Effects of WNT1 c.110 T>C and c.505G>T mutations on osteoblast differentiation via the WNT1/β-catenin signaling pathway.
Mesenchymal stem cells ameliorate silica-induced pulmonary fibrosis by inhibition of inflammation and epithelial-mesenchymal transition.
TROAP regulates cell cycle and promotes tumor progression through Wnt/β-Catenin signaling pathway in glioma cells.
A protocol for in vivo analysis of liver tumorigenesis in mice using sleeping beauty transposon system.
Hypoxic postconditioning promotes mitophagy against transient global cerebral ischemia via PINK1/Parkin-induced mitochondrial ubiquitination in adult rats.
Long noncoding RNA AFAP1-AS1 promotes tumor progression and invasion by regulating the miR-2110/Sp1 axis in triple-negative breast cancer.
Arginine methylation of METTL14 promotes RNA N6-methyladenosine modification and endoderm differentiation of mouse embryonic stem cells.
ALS/FTD mutations in UBQLN2 are linked to mitochondrial dysfunction through loss-of-function in mitochondrial protein import.
Single-cell RNA-seq reveals fibroblast heterogeneity and increased mesenchymal fibroblasts in human fibrotic skin diseases.
OGA is associated with deglycosylation of NONO and the KU complex during DNA damage repair.
Exosomal SNHG16 secreted by CSCs promotes glioma development via TLR7.
UBQLN2-HSP70 axis reduces poly-Gly-Ala aggregates and alleviates behavioral defects in the C9ORF72 animal model.
Cold Atmospheric Plasma Promotes Killing of Staphylococcus aureus by Macrophages.
MicroRNA-139 inhibits pancreatic-cancer carcinogenesis by suppressing RalB via the Ral/RAC/PI3K pathway.
Nimodipine inhibits intestinal and aortic smooth muscle contraction by regulating Ca2+-activated Cl- channels.
Mechanosensitive expression of lamellipodin promotes intracellular stiffness, cyclin expression and cell proliferation.
Prrx1 promotes stemness and angiogenesis via activating TGF-β/smad pathway and upregulating proangiogenic factors in glioma.
G-protein-coupled receptor GPR17 inhibits glioma development by increasing polycomb repressive complex 1-mediated ROS production.
RNF220-mediated ubiquitination promotes aggresomal accumulation and autophagic degradation of cytoplasmic Gli via HDAC6.
Vincristine attenuates cardiac fibrosis through the inhibition of NLRP3 inflammasome activation.
Renoprotective effects of levosimendan on acute kidney injury following cardiac arrest via anti-inflammation, anti-apoptosis, and ERK activation.
Selenium Status in Diet Affects Acetaminophen-Induced Hepatotoxicity via Interruption of Redox Environment.
STAT1 epigenetically regulates LCP2 and TNFAIP2 by recruiting EP300 to contribute to the pathogenesis of inflammatory bowel disease.
Reducing lipofuscin accumulation and cardiomyocytic senescence of aging heart by enhancing autophagy.
Tumors exploit FTO-mediated regulation of glycolytic metabolism to evade immune surveillance.
A kinome screen reveals that Nemo-like kinase is a key suppressor of hepatic gluconeogenesis.
VEGF/Src signaling mediated pleural barrier damage and increased permeability contributes to subpleural pulmonary fibrosis.
High uric acid induces liver fat accumulation via ROS/JNK/AP-1 signaling.
THAP11 down-regulation may contribute to cardio-protective effects of sevoflurane anesthesia: Evidence from clinical and molecular evidence.
Nicotinamide mononucleotide attenuates isoproterenol-induced cardiac fibrosis by regulating oxidative stress and Smad3 acetylation.
MIR29A Impedes Metastatic Behaviors in Hepatocellular Carcinoma via Targeting LOX, LOXL2, and VEGFA.
Inducible ATP1B1 Upregulates Antiviral Innate Immune Responses by the Ubiquitination of TRAF3 and TRAF6.
Microglial IL-10 and β-endorphin expression mediates gabapentinoids antineuropathic pain.
Expression of Cntn1 is regulated by stress and associated with anxiety and depression phenotypes.
GCH1 induces immunosuppression through metabolic reprogramming and IDO1 upregulation in triple-negative breast cancer.
LXRβ is involved in the control of platelet production from megakaryocytes.
Wireless Localized Electrical Stimulation Generated by an Ultrasound-Driven Piezoelectric Discharge Regulates Proinflammatory Macrophage Polarization.
Multiregional profiling of the brain transmembrane proteome uncovers novel regulators of depression.
Sulforaphane Balances Ca2+ Homeostasis Injured by Excessive Fat via Mitochondria-Associated Membrane (MAM).
Enhancing immunogenicity of HPV16 E7 DNA vaccine by conjugating codon-optimized GM-CSF to HPV16 E7 DNA.
The LncRNA RP11-279C4.1 Enhances the Malignant Behaviour of Glioma Cells and Glioma Stem-Like Cells by Regulating the miR-1273g-3p/CBX3 Axis.
Generation of a TLR2 homozygous knockout human embryonic stem cell line WAe001-A-64 using CRISPR/Cas9 editing.
Neutrophil extracellular traps promote gastric cancer metastasis by inducing epithelial‑mesenchymal transition.
Selenium triggers Nrf2-AMPK crosstalk to alleviate cadmium-induced autophagy in rabbit cerebrum.
EZH2 regulates expression of FOXC1 by mediating H3K27me3 in breast cancers.
Exosomes are involved in total body irradiation-induced intestinal injury in mice.
YB1 regulates miR-205/200b-ZEB1 axis by inhibiting microRNA maturation in hepatocellular carcinoma.
A multifaceted role of progranulin in regulating amyloid-beta dynamics and responses.
MiR-706 alleviates white matter injury via downregulating PKCα/MST1/NF-κB pathway after subarachnoid hemorrhage in mice.
Direct control of store-operated calcium channels by ultrafast laser.
Aflatoxin B1 inhibited autophagy flux by inducing lysosomal alkalinization in HepG2 cells.
MicroRNA-215-5p inhibits the proliferation of keratinocytes and alleviates psoriasis-like inflammation by negatively regulating DYRK1A and its downstream signalling pathways.
Mechanistic insights into mitochondrial tRNAAla 3'-end metabolism deficiency.
MACF1 promotes osteoblast differentiation by sequestering repressors in cytoplasm.
Overexpression of SERPINA3 promotes tumor invasion and migration, epithelial-mesenchymal-transition in triple-negative breast cancer cells.
Human umbilical cord mesenchymal stem cell-derived exosomes inhibit migration and invasion of breast cancer cells via miR-21-5p/ZNF367 pathway.
Caspase-1 inhibits IFN-β production via cleavage of cGAS during M. bovis infection.
METTL16 promotes cell proliferation by up-regulating cyclin D1 expression in gastric cancer.
Different roles of BAG3 in cardiac physiological hypertrophy and pathological remodeling.
Cancer cell-intrinsic STING is associated with CD8 + T-cell infiltration and might serve as a potential immunotherapeutic target in hepatocellular carcinoma.
Effects of TRIM59 on RAW264.7 macrophage gene expression and function.
Mechanism of validamycin A inhibiting DON biosynthesis and synergizing with DMI fungicides against Fusarium graminearum.
Effect of the interference with DRP1 expression on the biological characteristics of glioma stem cells.
C1orf61 promotes hepatocellular carcinoma metastasis and increases the therapeutic response to sorafenib.
Activation of Ca2+/Calmodulin-Dependent Protein Kinase II (CaMKII) with Lidocaine Provokes Pyroptosis of Glioblastoma Cells.
SNX17 protects the heart from doxorubicin-induced cardiotoxicity by modulating LMOD2 degradation.
Dihydrotanshinone I inhibits aortic valve interstitial cell calcification via the SMAD1/5/8/NF-κB/ERK pathway.
Fucoxanthin rescues dexamethasone induced C2C12 myotubes atrophy.
Tacrolimus inhibits oral carcinogenesis through cell cycle control.
Choline attenuates heat stress-induced oxidative injury and apoptosis in bovine mammary epithelial cells by modulating PERK/Nrf-2 signaling pathway.
Brevilin A inhibits NLRP3 inflammasome activation in vivo and in vitro by acting on the upstream of NLRP3-induced ASC oligomerization.
ASAP1 regulates the uptake of Mycobacterium tuberculosis H37Ra in THP1-derived macrophages by remodeling actin cytoskeleton.
Calycosin attenuates pulmonary fibrosis by the epithelial-mesenchymal transition repression upon inhibiting the AKT/GSK3β/β-catenin signaling pathway.
KIN17 promotes tumor metastasis by activating EMT signaling in luminal-A breast cancer.
C188-9 reduces TGF-β1-induced fibroblast activation and alleviates ISO-induced cardiac fibrosis in mice.
Protective effects of VMY-2-95 on corticosterone-induced injuries in mice and cellular models.
miRNA-194 predicts favorable prognosis in gastric cancer and inhibits gastric cancer cell growth by targeting CCND1.
Tubeimoside I improves endothelial function in sepsis via activation of SIRT3.
The Sonic Hedgehog signaling pathway regulates autophagy and migration in ovarian cancer.
Discovery of β-Carboline Derivatives as a Highly Potent Cardioprotectant against Myocardial Ischemia-Reperfusion Injury.
YBX1 is required for maintaining myeloid leukemia cell survival by regulating BCL2 stability in an m6A-dependent manner.
Intestinal Klebsiella pneumoniae infection enhances susceptibility to epileptic seizure which can be reduced by microglia activation.
Inhibition of xCT suppresses the efficacy of anti-PD-1/L1 melanoma treatment through exosomal PD-L1-induced macrophage M2 polarization.
The cardiac translational landscape reveals that micropeptides are new players involved in cardiomyocyte hypertrophy.
Prognostic signature composed of transcription factors accurately predicts the prognosis of gastric cancer patients.
Participation of Mind Bomb-2 in Sevoflurane Anesthesia Induces Cognitive Impairment in Aged Mice via Modulating Ferroptosis.
USP19 promotes hypoxia-induced mitochondrial division via FUNDC1 at ER-mitochondria contact sites.
Identification and optimization of 3-bromo-N'-(4-hydroxybenzylidene)-4-methylbenzohydrazide derivatives as mTOR inhibitors that induce autophagic cell death and apoptosis in triple-negative breast cancer.
The intrinsic role and mechanism of tumor expressed-CD38 on lung adenocarcinoma progression.
A flavonoid-rich Smilax china L. extract prevents obesity by upregulating the adiponectin-receptor/AMPK signalling pathway and modulating the gut microbiota in mice.
Lnc-STYK1-2 regulates bladder cancer cell proliferation, migration, and invasion by targeting miR-146b-5p expression and AKT/STAT3/NF-kB signaling.
Integrated bioinformatics analysis revealed the regulation of angiogenesis by tumor cells in hepatocellular carcinoma.
Anti-anemia drug FG4592 retards the AKI-to-CKD transition by improving vascular regeneration and antioxidative capability.
Glycoursodeoxycholic acid ameliorates diet-induced metabolic disorders with inhibiting endoplasmic reticulum stress.
Propofol differentially induces unconsciousness and respiratory depression through distinct interactions between GABAA receptor and GABAergic neuron in corresponding nuclei.
TBN improves motor function and prolongs survival in a TDP-43M337V mouse model of ALS.
Pterostilbene alleviates pulmonary fibrosis by regulating ASIC2.
Analysis of the Internal Hypoxic Environment in Solid Tumor Tissue Using a Folding Paper System.
The anti-dysenteric drug fraxetin enhances anti-tumor efficacy of gemcitabine and suppresses pancreatic cancer development by antagonizing STAT3 activation.
MINDY1 promotes bladder cancer progression by stabilizing YAP.
Serum exosomes from young rats improve the reduced osteogenic differentiation of BMSCs in aged rats with osteoporosis after fatigue loading in vivo.
Tree Shrew Cells Transduced with Human CD4 and CCR5 Support Early Steps of HIV-1 Replication, but Viral Infectivity Is Restricted by APOBEC3.
GNAI2 Promotes Proliferation and Decreases Apoptosis in Rabbit Melanocytes.
Behavioral effects of early-life exposure to perfluorooctanoic acid might synthetically link to multiple aspects of dopaminergic neuron development and dopamine functions in zebrafish larvae.
Phenethylamine in chlorella alleviates high-fat diet-induced mouse liver damage by regulating generation of methylglyoxal.
A CREB1-miR-181a-5p loop regulates the pathophysiologic features of bone marrow stromal cells in fibrous dysplasia of bone.
Autophagy-related circRNA evaluation reveals hsa_circ_0001747 as a potential favorable prognostic factor for biochemical recurrence in patients with prostate cancer.
Role of MCP-1 and IL-8 in viral anterior uveitis, and contractility and fibrogenic activity of trabecular meshwork cells.
Epitranscriptomic editing of the RNA N6-methyladenosine modification by dCasRx conjugated methyltransferase and demethylase.
Lactate secreted by PKM2 upregulation promotes Galectin-9-mediated immunosuppression via inhibiting NF-κB pathway in HNSCC.
SARS-CoV-2 Restructures the Host Chromatin Architecture.
Comparable radiation sensitivity in p53 wild-type and p53 deficient tumor cells associated with different cell death modalities.
A mesenchymal-like subpopulation in non-neuroendocrine SCLC contributes to metastasis.
TGF-β1-mediated exosomal lnc-MMP2-2 increases blood-brain barrier permeability via the miRNA-1207-5p/EPB41L5 axis to promote non-small cell lung cancer brain metastasis.
Inactivation of the tumor suppressor p53 by long noncoding RNA RMRP.
CaMKII and CaV3.2 T-type calcium channel mediate Connexin-43-dependent inflammation by activating astrocytes in vincristine-induced neuropathic pain.
Variations in Env at amino acids 328 and 330 affect HIV-1 replicative fitness and entry inhibitor sensitivity.
The molecular basis of coupling between poly(A)-tail length and translational efficiency.
MARCH6 promotes hepatocellular carcinoma development through up-regulation of ATF2.
Erlotinib protests against LPS-induced parthanatos through inhibiting macrophage surface TLR4 expression.
BMI1 activates P-glycoprotein via transcription repression of miR-3682-3p and enhances chemoresistance of bladder cancer cell.
Role of NLR family pyrin domain-containing 3 inflammasome in the activation of pancreatic stellate cells.
Chlamydia trachomatis Pgp3 protein regulates oxidative stress via activation of the Nrf2/NQO1 signal pathway.
The mechanisms of action of WeiChang'An Pill (WCAP) treat diarrhoea-predominant irritable bowel syndrome (IBS-D) using network pharmacology approach and in vivo studies.
Proteomics analysis in the kidney of mice following oral feeding Realgar.
Identification and validation of an immune-related prognostic signature and key gene in papillary thyroid carcinoma.
Nonstructural Protein NSs Hampers Cellular Antiviral Response through LSm14A during Severe Fever with Thrombocytopenia Syndrome Virus Infection.
Role of IL-6-IL-27 Complex in Host Antiviral Immune Response.
Protective effects and mechanisms of high-dose vitamin C on sepsis-associated cognitive impairment in rats.
Ubiquitin-specific protease 15 contributes to gastric cancer progression by regulating the Wnt/β-catenin signaling pathway.
LncRNA PCGEM1 induces proliferation and migration in non-small cell lung cancer cells through modulating the miR-590-3p/SOX11 axis.
Cyclophilin A Inhibits Human Respiratory Syncytial Virus (RSV) Replication by Binding to RSV-N through Its PPIase Activity.
S-Allylmercapto-N-acetylcysteine ameliorates elastase-induced chronic obstructive pulmonary disease in mice via regulating autophagy.
YTHDF2 facilitates UBXN1 mRNA decay by recognizing METTL3-mediated m6A modification to activate NF-κB and promote the malignant progression of glioma.
Repression of the AURKA-CXCL5 axis induces autophagic cell death and promotes radiosensitivity in non-small-cell lung cancer.
Epitranscriptomic addition of m6A regulates HIV-1 RNA stability and alternative splicing.
p55PIK deficiency and its NH2-terminal derivative inhibit inflammation and emphysema in COPD mouse model.
GALNT2 promotes cell proliferation, migration, and invasion by activating the Notch/Hes1-PTEN-PI3K/Akt signaling pathway in lung adenocarcinoma.
IL37 overexpression inhibits autophagy and apoptosis induced by hepatic ischemia reperfusion injury via modulating AMPK/mTOR/ULLK1 signalling pathways.
Seneca Valley Virus 3C Protease Induces Pyroptosis by Directly Cleaving Porcine Gasdermin D.
Long noncoding RNA BS-DRL1 modulates the DNA damage response and genome stability by interacting with HMGB1 in neurons.
Toll-like receptor-2 gene knockout results in neurobehavioral dysfunctions and multiple brain structural and functional abnormalities in mice.
Hepatocyte growth factor mediates a novel form of hepatic stem/progenitor cell-induced tolerance in a rat xenogeneic liver rejection model.
MicroRNA-124-3p affects myogenic differentiation of adipose-derived stem cells by targeting Caveolin-1 during pelvic floor dysfunction in Sprague Dawley rats.
Repressing PDCD4 activates JNK/ABCG2 pathway to induce chemoresistance to fluorouracil in colorectal cancer cells.
RNA-binding protein QKI suppresses breast cancer via RASA1/MAPK signaling pathway.
The Beneficial Role of Sunitinib in Tumor Immune Surveillance by Regulating Tumor PD-L1.
Preventive effect of dioscin against monosodium urate-mediated gouty arthritis through inhibiting inflammasome NLRP3 and TLR4/NF-κB signaling pathway activation: an in vivo and in vitro study.
ETV5 Regulates Hepatic Fatty Acid Metabolism Through PPAR Signaling Pathway.
TBC1D3 promotes neural progenitor proliferation by suppressing the histone methyltransferase G9a.
MicroRNA-489-3p Represses Hepatic Stellate Cells Activation by Negatively Regulating the JAG1/Notch3 Signaling Pathway.
FIGNL1 promotes non‑small cell lung cancer cell proliferation.
Parthenolide inhibits the tumor characteristics of renal cell carcinoma.
Dysfunction of Shh signaling activates autophagy to inhibit trophoblast motility in recurrent miscarriage.
Prostaglandin E2 serves a dual role in regulating the migration of dendritic cells.
Avasimibe exerts anticancer effects on human glioblastoma cells via inducing cell apoptosis and cell cycle arrest.
UHRF1 Knockdown Attenuates Cell Growth, Migration, and Invasion in Cutaneous Squamous Cell Carcinoma.
Flavonoid compound breviscapine suppresses human osteosarcoma Saos-2 progression property and induces apoptosis by regulating mitochondria-dependent pathway.
Nucleolin regulates 14-3-3ζ mRNA and promotes cofilin phosphorylation to induce tunneling nanotube formation.
Mefunidone ameliorates diabetic kidney disease in STZ and db/db mice.
Rapid antidepressant-like effect of Fructus Aurantii depends on cAMP-response element binding protein/Brain-derived neurotrophic facto by mediating synaptic transmission.
Effects of Y Box Binding Protein-1 in Progression and Prognosis of Cholangiocarcinoma.
Long noncoding RNA LINC00460 promotes the progression of cervical cancer via regulation of the miR-361-3p/Gli1 axis.
Long noncoding RNA TSLNC8 enhances pancreatic cancer aggressiveness by regulating CTNNB1 expression via association with HuR.
Hemizygous deletion of Tbk1 worsens neuromuscular junction pathology in TDP-43G298S transgenic mice.
MiR-19b-3p accelerates bone loss after spinal cord injury by suppressing osteogenesis via regulating PTEN/Akt/mTOR signalling.
Maltol prevents the progression of osteoarthritis by targeting PI3K/Akt/NF-κB pathway: In vitro and in vivo studies.
Mixed-lineage leukaemia 1 contributes to endometrial stromal cells progesterone responsiveness during decidualization.
Blocking VRK2 suppresses pulmonary adenocarcinoma progression via ERK1/2/AKT signal pathway by targeting miR-145-5p.
Treatment of keloids through Runx2 siRNA‑induced inhibition of the PI3K/AKT signaling pathway.
Protection against Dextran Sulfate Sodium-Induced Ulcerative Colitis in Mice by Neferine, A Natural Product from Nelumbo nucifera Gaertn.
Effect of HMGB1 on monocyte immune function in respiratory syncytial virus bronchiolitis.
miR-155-5p regulates macrophage M1 polarization and apoptosis in the synovial fluid of patients with knee osteoarthritis.
Contribution of DNA methyltransferases to spared nerve injury induced depression partially through epigenetically repressing Bdnf in hippocampus: Reversal by ketamine.
Suppressed nuclear envelope proteins activate autophagy of vascular smooth muscle cells during cyclic stretch application.
Inhibition of proliferation-linked signaling cascades with atractylenolide I reduces myofibroblastic phenotype and renal fibrosis.
P-glycoprotein deficiency enhances metabolic activation of and platelet response to clopidogrel through marked up-regulation of Cyp3a11 in mice: Direct evidence for the interplay between P-glycoprotein and Cyp3a.
NCBP3/SNHG6 inhibits GBX2 transcription in a histone modification manner to facilitate the malignant biological behaviour of glioma cells.
Targeted inhibition of Rev-erb-α/β limits ferroptosis to ameliorate folic acid-induced acute kidney injury.
The inhibition of colorectal cancer growth by the natural product macrocarpal I.
HSF1 functions as a key defender against palmitic acid-induced ferroptosis in cardiomyocytes.
Exosome-mediated delivery of antisense oligonucleotides targeting α-synuclein ameliorates the pathology in a mouse model of Parkinson's disease.
Elevated ZBTB7A expression in the tumor invasive front correlates with more tumor budding formation in gastric adenocarcinoma.
A SMOC2 variant inhibits BMP signaling by competitively binding to BMPR1B and causes growth plate defects.
Melatonin increases the chemosensitivity of diffuse large B-cell lymphoma cells to epirubicin by inhibiting P-glycoprotein expression via the NF-κB pathway.
miRNA-146a-5p mitigates stress-induced premature senescence of D-galactose-induced primary thymic stromal cells.
CLDN10 associated with immune infiltration is a novel prognostic biomarker for clear cell renal cell carcinoma.
Hyperglycemia-reduced NAD+ biosynthesis impairs corneal epithelial wound healing in diabetic mice.
NNT-induced tumor cell "slimming" reverses the pro-carcinogenesis effect of HIF2a in tumors.
Disrupted glucose homeostasis and skeletal-muscle-specific glucose uptake in an exocyst knockout mouse model.
Determining the quantitative relationship between glycolysis and GAPDH in cancer cells exhibiting the Warburg effect.
Salvianolic acid B blocks hepatic stellate cell activation via FGF19/FGFR4 signaling.
Melatonin ameliorates hepatic steatosis by inhibiting NLRP3 inflammasome in db/db mice.
Valproic acid Suppresses Breast Cancer Cell Growth Through Triggering Pyruvate Kinase M2 Isoform Mediated Warburg Effect.
Electroacupuncture Attenuates Morphine Tolerance in Rats with Bone Cancer Pain by Inhibiting PI3K/Akt/JNK1/2 Signaling Pathway in the Spinal Dorsal Horn.
Thermoresponsive GenisteinNLC-dexamethasone-moxifloxacin multi drug delivery system in lens capsule bag to prevent complications after cataract surgery.
Antioxidant and Immunomodulatory Properties of Partially purified Exopolysaccharide from Lactobacillus Casei Isolated from Chinese Northeast Sauerkraut.
Effects of ER-resident and secreted AGR2 on cell proliferation, migration, invasion, and survival in PANC-1 pancreatic cancer cells.
Intraperitoneal injection of Desferal® alleviated the age-related bone loss and senescence of bone marrow stromal cells in rats.
Indoleamine 2,3-dioxygenase 1 limits hepatic inflammatory cells recruitment and promotes bile duct ligation-induced liver fibrosis.
Rabies virus matrix protein targets host actin cytoskeleton: a protein-protein interaction analysis.
Lnc-GAN1 expression is associated with good survival and suppresses tumor progression by sponging mir-26a-5p to activate PTEN signaling in non-small cell lung cancer.
MCCC2 promotes HCC development by supporting leucine oncogenic function.
Environmental noise stress disturbs commensal microbiota homeostasis and induces oxi-inflammmation and AD-like neuropathology through epithelial barrier disruption in the EOAD mouse model.
miR-142 downregulation alleviates rat PTSD-like behaviors, reduces the level of inflammatory cytokine expression and apoptosis in hippocampus, and upregulates the expression of fragile X mental retardation protein.
Leptin Receptor (LEPR) promotes proliferation, migration, and invasion and inhibits apoptosis in hepatocellular carcinoma by regulating ANXA7.
Tumor genotype dictates radiosensitization after Atm deletion in primary brainstem glioma models.
Improvement of obesity-associated disorders by a small-molecule drug targeting mitochondria of adipose tissue macrophages.
Interplay of opposing fate choices stalls oncogenic growth in murine skin epithelium.
Neuroprotective effects of SOX5 against ischemic stroke by regulating VEGF/PI3K/AKT pathway.
Discovery and proteomics analysis of effective compounds in Valeriana jatamansi jones for the treatment of anxiety.
Angiogenesis is promoted by exosomal DPP4 derived from 5-fluorouracil-resistant colon cancer cells.
LncRNA H19-Derived miR-675-5p Accelerates the Invasion of Extravillous Trophoblast Cells by Inhibiting GATA2 and Subsequently Activating Matrix Metalloproteinases.
Connective tissue growth factor promotes chemotaxis of preosteoblasts through integrin α5 and Ras during tensile force-induced intramembranous osteogenesis.
Echinatin effectively protects against NLRP3 inflammasome-driven diseases by targeting HSP90.
Vitamin D alleviates liver fibrosis by inhibiting histidine-rich calcium binding protein (HRC).
Immunophenotype of Gastric Tumors Unveils a Pleiotropic Role of Regulatory T Cells in Tumor Development.
Long-read transcriptome sequencing reveals abundant promoter diversity in distinct molecular subtypes of gastric cancer.
A novel oncotherapy strategy: Direct thrombin inhibitors suppress progression, dissemination and spontaneous metastasis in non-small cell lung cancer.
Discovery of a Functional Covalent Ligand Targeting an Intrinsically Disordered Cysteine within MYC.
Human umbilical cord mesenchymal stem cell-derived exosomal miR-146a-5p reduces microglial-mediated neuroinflammation via suppression of the IRAK1/TRAF6 signaling pathway after ischemic stroke.
SERCA2a ameliorates cardiomyocyte T-tubule remodeling via the calpain/JPH2 pathway to improve cardiac function in myocardial ischemia/reperfusion mice.
Identification of Cleavage Sites Proteolytically Processed by NS2B-NS3 Protease in Polyprotein of Japanese Encephalitis Virus.
An Autism-Associated Mutation Impairs Neuroligin-4 Glycosylation and Enhances Excitatory Synaptic Transmission in Human Neurons.
Notoginsenoside R1 attenuates breast cancer progression by targeting CCND2 and YBX3.
Adipose-derived stromal cells improve functional recovery after spinal cord injury through TGF-β1/Smad3/PLOD2 pathway activation.
The mitochondrial protein ERAL1 suppresses RNA virus infection by facilitating RIG-I-like receptor signaling.
Development of DNA Vaccine Targeting E6 and E7 Proteins of Human Papillomavirus 16 (HPV16) and HPV18 for Immunotherapy in Combination with Recombinant Vaccinia Boost and PD-1 Antibody.
Hsa_circ_0007456 regulates the natural killer cell-mediated cytotoxicity toward hepatocellular carcinoma via the miR-6852-3p/ICAM-1 axis.
Human RECQL5 promotes metastasis and resistance to cisplatin in non-small cell lung cancer.
MicroRNA-150 affects endoplasmic reticulum stress via MALAT1-miR-150 axis-mediated NF-κB pathway in LPS-challenged HUVECs and septic mice.
Discovery of a novel small-molecule inhibitor of Fam20C that induces apoptosis and inhibits migration in triple negative breast cancer.
Atractylodis macrocephalae polysaccharides protect against DSS-induced intestinal injury through a novel lncRNA ITSN1-OT1.
Circ_0001438 participates in the pathogenesis of preeclampsia via the circ_0001438/miR-942/NLRP3 regulatory network.
Single cell transcriptomic analysis of human pluripotent stem cell chondrogenesis.
Functional constipation induces bladder overactivity associated with upregulations of Htr2 and Trpv2 pathways.
Genome-wide Screens Identify Lineage- and Tumor-Specific Genes Modulating MHC-I- and MHC-II-Restricted Immunosurveillance of Human Lymphomas.
miR-199b-5p enhances the proliferation of medullary thymic epithelial cells via regulating Wnt signaling by targeting Fzd6.
The DDX39B/FUT3/TGFβR-I axis promotes tumor metastasis and EMT in colorectal cancer.
Cellular and molecular landscape of mammalian sinoatrial node revealed by single-cell RNA sequencing.
Transcription elongation factor A-like 7, regulated by miR-758-3p inhibits the progression of melanoma through decreasing the expression levels of c-Myc and AKT1.
Mtu1 defects are correlated with reduced osteogenic differentiation.
Knockdown of CENPF inhibits the progression of lung adenocarcinoma mediated by ERβ2/5 pathway.
Tetrachlorobenzoquinone exhibits immunotoxicity by inducing neutrophil extracellular traps through a mechanism involving ROS-JNK-NOX2 positive feedback loop.
Canstatin represses glioma growth by inhibiting formation of VM-like structures.
SQSTM1/ p62 oligomerization contributes to Aβ-induced inhibition of Nrf2 signaling.
Kiaa0101 serves as a prognostic marker and promotes invasion by regulating p38/snail1 pathway in glioma.
Eldecalcitol induces apoptosis and autophagy in human osteosarcoma MG-63 cells by accumulating ROS to suppress the PI3K/Akt/mTOR signaling pathway.
Gastrin-17 induces gastric cancer cell epithelial-mesenchymal transition via the Wnt/β-catenin signaling pathway.
RNA-binding protein HuR suppresses senescence through Atg7 mediated autophagy activation in diabetic intervertebral disc degeneration.
Kcnh2 mediates FAK/AKT-FOXO3A pathway to attenuate sepsis-induced cardiac dysfunction.
lncRNA NEAT1 ameliorates LPS‑induced inflammation in MG63 cells by activating autophagy and suppressing the NLRP3 inflammasome.
lncRNA FOXP4‑AS1 predicts poor prognosis and accelerates the progression of mantle cell lymphoma through the miR‑423‑5p/NACC1 pathway.
Circular RNA circNFATC3 acts as a miR-9-5p sponge to promote cervical cancer development by upregulating SDC2.
OPA1 haploinsufficiency due to a novel splicing variant resulting in mitochondrial dysfunction without mitochondrial DNA depletion.
CRISPR/Cas9 screening identifies a kinetochore-microtubule dependent mechanism for Aurora-A inhibitor resistance in breast cancer.
PRMT1 enhances oncogenic arginine methylation of NONO in colorectal cancer.
miR-23a-3p regulated by LncRNA SNHG5 suppresses the chondrogenic differentiation of human adipose-derived stem cells via targeting SOX6/SOX5.
MicroRNA-936/ERBB4/Akt axis exhibits anticancer properties of gastric cancer through inhibition of cell proliferation, migration, and invasion.
The Kv1.3 ion channel acts as a host factor restricting viral entry.
Rosmarinic acid exerts an antagonistic effect on nonalcoholic fatty liver disease by regulating the YAP1/TAZ-PPARγ/PGC-1α signaling pathway.
COPII mitigates ER stress by promoting formation of ER whorls.
UBE2O targets Mxi1 for ubiquitination and degradation to promote lung cancer progression and radioresistance.
TDP-43 aggregation induced by oxidative stress causes global mitochondrial imbalance in ALS.
The interaction between lipocalin 2 and dipyridine ketone hydrazone dithiocarbamte may influence respective function in proliferation and metastasis-related gene expressions in HepG2 cell.
M2 macrophage-derived G-CSF promotes trophoblasts EMT, invasion and migration via activating PI3K/Akt/Erk1/2 pathway to mediate normal pregnancy.
LINC01116 promotes proliferation and migration of endometrial stromal cells by targeting FOXP1 via sponging miR-9-5p in endometriosis.
FoxM1 promotes Wnt/β-catenin pathway activation and renal fibrosis via transcriptionally regulating multi-Wnts expressions.
AGGF1 inhibits the expression of inflammatory mediators and promotes angiogenesis in dental pulp cells.
Ptk2b deletion improves mice folliculogenesis and fecundity via inhibiting follicle loss mediated by Erk pathway.
Molecular mechanism underlying miR‑130b‑Sp1 transcriptional regulation in LPS‑induced upregulation of MUC5AC in the bile duct epithelium.
Knockdown of long non‑coding RNA ANRIL inhibits the proliferation and promotes the apoptosis of Burkitt lymphoma cells through the TGF‑β1 signaling pathway.
Matrix metalloproteinase 3 regulates angiotensin II‑induced myocardial fibrosis cell viability, migration and apoptosis.
Benzidine promotes the stemness of bladder cancer stem cells via activation of the Sonic hedgehog pathway.
Crosstalk between phosphorylation and ubiquitination is involved in high salt-induced WNK4 expression.
Dysregulation of phosphoproteins in hepatocellular carcinoma revealed via quantitative analysis of the phosphoproteome.
Inhibition of autophagy aggravates molybdenum-induced mitochondrial dysfunction by aggravating oxidative stress in duck renal tubular epithelial cells.
Clinical and molecular characterization of thirty Chinese patients with congenital lipoid adrenal hyperplasia.
Viral RNA-binding ability conferred by SUMOylation at PB1 K612 of influenza A virus is essential for viral pathogenesis and transmission.
Predicting therapeutic drugs for hepatocellular carcinoma based on tissue-specific pathways.
Cryptotanshinone specifically suppresses NLRP3 inflammasome activation and protects against inflammasome-mediated diseases.
Genistein inhibits radiation-induced invasion and migration of glioblastoma cells by blocking the DNA-PKcs/Akt2/Rac1 signaling pathway.
20-HETE downregulates Na/K-ATPase α1 expression via the ubiquitination pathway.
Loss of STAT5A promotes glucose metabolism and tumor growth through miRNA-23a-AKT signaling in hepatocellular carcinoma.
Compound heterozygous mutation of the ASXL3 gene causes autosomal recessive congenital heart disease.
Whole-Transcriptome Profiling of Human Heart Tissues Reveals the Potential Novel Players and Regulatory Networks in Different Cardiomyopathy Subtypes of Heart Failure.
Knockdown of dual oxidase 1 suppresses activin A-induced fibrosis in cardiomyocytes via the reactive oxygen species-dependent pyroptotic pathway.
MicroRNA-520c-3p targeting of RelA/p65 suppresses atherosclerotic plaque formation.
MiR-146a mediates TLR-4 signaling pathway to affect myocardial fibrosis in rat constrictive pericarditis model.
RabGEF1 functions as an oncogene in U251 glioblastoma cells and is involved in regulating AKT and Erk pathways.
A loss-of-function mutation p.T256M in NDRG4 is implicated in the pathogenesis of pulmonary atresia with ventricular septal defect (PA/VSD) and tetralogy of Fallot (TOF).
Layer-by-layer self-assembly polyelectrolytes loaded with cyclic adenosine monophosphate enhances the osteo/odontogenic differentiation of stem cells from apical papilla.
HOXA10 mediates epithelial-mesenchymal transition to promote gastric cancer metastasis partly via modulation of TGFB2/Smad/METTL3 signaling axis.
FKBP10 promotes proliferation of glioma cells via activating AKT-CREB-PCNA axis.
DDB2 regulates DNA replication through PCNA-independent degradation of CDT2.
miR-374 improves cerebral ischemia reperfusion injury by targeting Wnt5a.
Adipocyte-specific deletion of zinc finger protein 407 results in lipodystrophy and insulin resistance in mice.
Humanin regulates oxidative stress in the ovaries of polycystic ovary syndrome patients via the Keap1/Nrf2 pathway.
RTN1-C mediates cerebral ischemia/reperfusion injury via modulating autophagy.
Long non-coding RNA CCDC183-AS1 acts AS a miR-589-5p sponge to promote the progression of hepatocellular carcinoma through regulating SKP1 expression.
miR-224-5p Contained in Urinary Extracellular Vesicles Regulates PD-L1 Expression by Inhibiting Cyclin D1 in Renal Cell Carcinoma Cells.
Angiopoietin 2 stimulates trophoblast invasion via a mechanism associated with JNK signaling.
Prpf31 is essential for the survival and differentiation of retinal progenitor cells by modulating alternative splicing.
Cancer-associated fibroblast-derived SDF-1 induces epithelial-mesenchymal transition of lung adenocarcinoma via CXCR4/β-catenin/PPARδ signalling.
UBE3C promotes proliferation and inhibits apoptosis by activating the β-catenin signaling via degradation of AXIN1 in gastric cancer.
Inhibition of the Otub1/c-Maf axis by the herbal acevaltrate induces myeloma cell apoptosis.
Radiotherapy and immunotherapy converge on elimination of tumor-promoting erythroid progenitor cells through adaptive immunity.
p53 induces ARTS to promote mitochondrial apoptosis.
Pterostilbene inhibits gallbladder cancer progression by suppressing the PI3K/Akt pathway.
Genome-wide analysis of pseudogenes reveals HBBP1's human-specific essentiality in erythropoiesis and implication in β-thalassemia.
Abnormal level of paxillin in cervical cancer cells is involved in tumor progression and invasion.
Glycogen synthase kinase 3 beta inhibitor SB216763 improves Kir2.1 expression after myocardia infraction in rats.
Nuclear factor Y participates in alcoholic liver disease by activating SREBP1 expression in mice.
SFPQ regulates the accumulation of RNA foci and dipeptide repeat proteins from the expanded repeat mutation in C9orf72.
GBP5 drives malignancy of glioblastoma via the Src/ERK1/2/MMP3 pathway.
LncRNA CDKN2B-AS1 stabilized by IGF2BP3 drives the malignancy of renal clear cell carcinoma through epigenetically activating NUF2 transcription.
E3 ligase Nedd4l promotes antiviral innate immunity by catalyzing K29-linked cysteine ubiquitination of TRAF3.
LncRNA HOXA-AS3 promotes gastric cancer progression by regulating miR-29a-3p/LTβR and activating NF-κB signaling.
Critical roles of sphingosine kinase 1 in the regulation of neuroinflammation and neuronal injury after spinal cord injury.
Direct activation of endothelial cells by SARS-CoV-2 nucleocapsid protein is blocked by Simvastatin.
Hepatic connective tissue growth factor expression and regulation differ between non-steatotic and non-alcoholic steatotic livers from brain-dead donor.
CREB1 protects against the renal injury in a rat model of kidney stone disease and calcium oxalate monohydrate crystals-induced injury in NRK-52E cells.
Down-regulation of A3AR signaling by IL-6-induced GRK2 activation contributes to Th17 cell differentiation.
Nobiletin downregulates the SKP2-p21/p27-CDK2 axis to inhibit tumor progression and shows synergistic effects with palbociclib on renal cell carcinoma.
RECQL4 regulates DNA damage response and redox homeostasis in esophageal cancer.
Gentisic acid prevents diet-induced obesity in mice by accelerating the thermogenesis of brown adipose tissue.
Uric acid inhibits HMGB1-TLR4-NF-κB signaling to alleviate oxygen-glucose deprivation/reoxygenation injury of microglia.
A novel regulatory loop miR-101/ANXA2/EGR1 mediates malignant characteristics of liver cancer stem cells.
DUOX2 promotes the progression of colorectal cancer cells by regulating the AKT pathway and interacting with RPL3.
Icariside I specifically facilitates ATP or nigericin-induced NLRP3 inflammasome activation and causes idiosyncratic hepatotoxicity.
The DNA methylation-regulated MCTP1 activates the drug-resistance of esophageal cancer cells.
Formononetin attenuates atopic dermatitis by upregulating A20 expression via activation of G protein-coupled estrogen receptor.
Gas6 or Mer deficiency ameliorates silica-induced autophagosomes accumulation in mice lung.
Berberine regulates macrophage polarization through IL-4-STAT6 signaling pathway in Helicobacter pylori-induced chronic atrophic gastritis.
The PDZ Domain Protein SYNJ2BP Regulates GRK-Dependent Sst2A Phosphorylation and Downstream MAPK Signaling.
ATM inhibition enhances cancer immunotherapy by promoting mtDNA leakage and cGAS/STING activation.
The S1PR1 agonist SEW2871 promotes the survival of skin flap.
Red ginseng has stronger anti-aging effects compared to ginseng possibly due to its regulation of oxidative stress and the gut microbiota.
LncRNA CAIF suppresses LPS-induced inflammation and apoptosis of cardiomyocytes through regulating miR-16 demethylation.
Mechanism of neutrophil extracellular traps generation and their role in trophoblasts apoptosis in gestational diabetes mellitus.
Ginsenoside Rb1 alleviates liver injury induced by 3-chloro-1,2-propanediol by stimulating autophagic flux.
Maternal Benzophenone Exposure Impairs Hippocampus Development and Cognitive Function in Mouse Offspring.
Targeting conserved N-glycosylation blocks SARS-CoV-2 variant infection in vitro.
MiR-192-5p suppresses M1 macrophage polarization via epiregulin (EREG) downregulation in gouty arthritis.
Molecular Mechanism of the ATF6α/S1P/S2P Signaling Pathway in Hippocampal Neuronal Apoptosis in SPS Rats.
Trametinib enhances ATRA-induced differentiation in AML cells.
Increased expression of PSME2 is associated with clear cell renal cell carcinoma invasion by regulating BNIP3‑mediated autophagy.
Wei Chang An pill regulates gastrointestinal motility in a bidirectional manner.
CoCrMo-Nanoparticles induced peri-implant osteolysis by promoting osteoblast ferroptosis via regulating Nrf2-ARE signalling pathway.
Bone marrow macrophage-derived exosomal miR-143-5p contributes to insulin resistance in hepatocytes by repressing MKP5.
Splicing factor proline and glutamine rich intron retention, reduced expression and aggregate formation are pathological features of amyotrophic lateral sclerosis.
Role of miR-145-5p/ CD40 in the inflammation and apoptosis of HUVECs induced by PM2.5.
Endoplasmic reticulum stress pathway mediates T-2 toxin-induced chondrocyte apoptosis.
YTHDF1 promotes the proliferation, migration, and invasion of prostate cancer cells by regulating TRIM44.
Activation of SK3 channel plays a pivotal role in modulation of trigeminal neuralgia.
Endothelial METTL3 (Methyltransferase-Like 3) Inhibits Fibrinolysis by Promoting PAI-1 (Plasminogen Activator Inhibitor-1) Expression Through Enhancing Jun Proto-Oncogene N6-Methyladenosine Modification.
Exposure interval to ambient fine particulate matter (PM2.5) collected in Southwest China induced pulmonary damage through the Janus tyrosine protein kinase-2/signal transducer and activator of transcription-3 signaling pathway both in vivo and in vitro.
Lobetyolin inhibits the proliferation of breast cancer cells via ASCT2 down-regulation-induced apoptosis.
Insulin-like growth factor reduced against decabromodiphenyl ether-209-induced neurodevelopmental toxicity in vivo and in vitro.
Non-canonical activation of the ER stress sensor ATF6 by Legionella pneumophila effectors.
Expression of CD47 in the pancreatic β-cells of people with recent-onset type 1 diabetes varies according to disease endotype.
Two Inhibitors Against the 3C-Like Proteases of Swine Coronavirus and Feline Coronavirus.
Angiomotin-like 1 plays a tumor-promoting role in glioma by enhancing the activation of YAP1 signaling.
Amelioratory effect of neoandrographolide on myocardial ischemic-reperfusion injury by its anti-inflammatory and anti-apoptotic activities.
Dual inhibition of EGFR and IL-6-STAT3 signalling by miR-146b: a potential targeted therapy for epithelial ovarian cancer.
CircPrkcsh, a circular RNA, contributes to the polarization of microglia towards the M1 phenotype induced by spinal cord injury and acts via the JNK/p38 MAPK pathway.
BAIAP2L2 promotes the proliferation, migration and invasion of osteosarcoma associated with the Wnt/β-catenin pathway.
Mdivi-1 alleviates atopic dermatitis through the inhibition of NLRP3 inflammasome.
Mitophagy mediates metabolic reprogramming of induced pluripotent stem cells undergoing endothelial differentiation.
Blockade of JAK2 signaling produces immunomodulatory effect to preserve pancreatic homeostasis in severe acute pancreatitis.
Protective effect of Idelalisib on carbon tetrachloride-induced liver fibrosis via microRNA-124-3P/phosphatidylinositol-3-hydroxykinase signalling pathway.
MET inhibition enhances PARP inhibitor efficacy in castration-resistant prostate cancer by suppressing the ATM/ATR and PI3K/AKT pathways.
Depletion of m6 A reader protein YTHDC1 induces dilated cardiomyopathy by abnormal splicing of Titin.
hsa‑miR‑429 targets CBX8 to promote cell apoptosis in diffuse large B‑cell lymphoma.
Peroxisome proliferator‑activated receptor β/δ regulates cerebral vasospasm after subarachnoid hemorrhage via modulating vascular smooth muscle cells phenotypic conversion.
MicroRNA-602 prevents the development of inflammatory bowel diseases in a microbiota-dependent manner.
Diterpenoid alkaloids from Delphinium forrestii var. viride and their anti-inflammation activity.
MicroRNA-455-5p/CPEB1 pathway mediates Aβ-related learning and memory deficits in a mouse model of Alzheimer's disease.
Resveratrol and its derivative pterostilbene attenuate oxidative stress-induced intestinal injury by improving mitochondrial redox homeostasis and function via SIRT1 signaling.
Isosteroidal alkaloids from Fritillaria hupehensis Hsiao et K.C.Hsia: Synthesis and biological evaluation of alkaloid derivatives as potential cytotoxic agents.
CUL3 (cullin 3)-mediated ubiquitination and degradation of BECN1 (beclin 1) inhibit autophagy and promote tumor progression.
Ferritinophagy is involved in the zinc oxide nanoparticles-induced ferroptosis of vascular endothelial cells.
Long noncoding RNA (lncRNA) EIF3J-DT induces chemoresistance of gastric cancer via autophagy activation.
Lanthanum chloride induces autophagy in primary cultured rat cortical neurons through Akt/mTOR and AMPK/mTOR signaling pathways.
Pentagalloylglucose reduces AGE-induced inflammation by activating Nrf2/HO-1 and inhibiting the JAK2/STAT3 pathway in mesangial cells.
Pyruvate kinase M2 (PKM2) interacts with activating transcription factor 2 (ATF2) to bridge glycolysis and pyroptosis in microglia.
LncRNA RP1-86C11.7 exacerbates the glioma progression and oncogenicity by hsa-miR-144-3p/TFRC signaling.
Ablation of USP21 in skeletal muscle promotes oxidative fibre phenotype, inhibiting obesity and type 2 diabetes.
Linc00467 promotion of gastric cancer development by directly regulating miR-7-5p expression and downstream epidermal growth factor receptor.
Hsa_circ_0030586 promotes epithelial-mesenchymal transition in prostate cancer via PI3K-AKT signaling.
Ubiquitin-associated protein 2 like (UBAP2L) enhances growth and metastasis of gastric cancer cells.
Orosomucoid 1 promotes epirubicin resistance in breast cancer by upregulating the expression of matrix metalloproteinases 2 and 9.
Solid lipid nanoparticle delivery of rhynchophylline enhanced the efficiency of allergic asthma treatment via the upregulation of suppressor of cytokine signaling 1 by repressing the p38 signaling pathway.
MiR-1224-5p attenuates polycystic ovary syndrome through inhibiting NOD-like receptor protein 3 inflammasome activation via targeting Forkhead box O 1.
Long non-coding RNA LOC107985656 represses the proliferation of hepatocellular carcinoma cells through activation of the tumor-suppressive Hippo pathway.
Impact of hepatocyte-specific deletion of staphylococcal nuclease and tudor domain containing 1 (SND1) on liver insulin resistance and acute liver failure of mice.
Dynamic Dissection of Dynein and Kinesin-1 Cooperatively Mediated Intercellular Transport of Porcine Epidemic Diarrhea Coronavirus along Microtubule Using Single Virus Tracking.
Site-specific SUMOylation of viral polymerase processivity factor: a way of localizingtoND10 subnuclear domains for restricted and self-controlled reproduction of herpesvirus.
Long non-coding RNA (lncRNA) PGM5P4-AS1 inhibits lung cancer progression by up-regulating leucine zipper tumor suppressor (LZTS3) through sponging microRNA miR-1275.
Catalpol ameliorates psoriasis-like phenotypes via SIRT1 mediated suppression of NF-κB and MAPKs signaling pathways.
A novel circular RNA (hsa_circ_0059930)-mediated miRNA-mRNA axis in the lipopolysaccharide-induced acute lung injury model of MRC-5 cells.
Long intergenic noncoding RNA00265 promotes proliferation of gastric cancer via the microRNA-144-3p/Chromobox 4 axis.
Tyrosine kinase nonreceptor 1 (TNK1) knockdown ameliorates hemorrhage shock-induced kidney injury via inhibiting macrophage M1 polarization.
Spatiotemporal regulation of JAZ4 expression and splicing contribute to ethylene- and auxin-mediated responses in Arabidopsis roots.
Veratric acid alleviates liver ischemia/reperfusion injury by activating the Nrf2 signaling pathway.
The impact of tobacco exposure on tumor microenvironment and prognosis in lung adenocarcinoma by integrative analysis of multi-omics data.
Sulfiredoxin-1 protects retinal ganglion cells from high glucose-induced oxidative stress and inflammatory injury by potentiating Nrf2 signaling via the Akt/GSK-3β pathway.
Topoisomerase 2 inhibitor etoposide promotes interleukin-10 production in LPS-induced macrophages via upregulating transcription factor Maf and activating PI3K/Akt pathway.
Aggregation-Induced Emission (AIE) Nanoparticles-Assisted NIR-II Fluorescence Imaging-Guided Diagnosis and Surgery for Inflammatory Bowel Disease (IBD).
NuMA regulates mitotic spindle assembly, structural dynamics and function via phase separation.
Uncovering a conserved vulnerability site in SARS-CoV-2 by a human antibody.
miR-140-3p enhanced the osteo/odontogenic differentiation of DPSCs via inhibiting KMT5B under hypoxia condition.
RND3 attenuates oxidative stress and vascular remodeling in spontaneously hypertensive rat via inhibiting ROCK1 signaling.
(20S) Ginsenoside Rh2 Exerts Its Anti-Tumor Effect by Disrupting the HSP90A-Cdc37 System in Human Liver Cancer Cells.
Glucocorticoid receptor regulates PD-L1 and MHC-I in pancreatic cancer cells to promote immune evasion and immunotherapy resistance.
Berberrubine attenuates potassium oxonate- and hypoxanthine-induced hyperuricemia by regulating urate transporters and JAK2/STAT3 signaling pathway.
Ultrasound triggered topical delivery of Bmp7 mRNA for white fat browning induction via engineered smart exosomes.
Efficient induction of proximity-dependent labelling by biotin feeding in BMAL1-BioID knock-in mice.
USP30-AS1 contributes to mitochondrial quality control in glioblastoma cells.
LRRC4 mediates the formation of circular RNA CD44 to inhibitGBM cell proliferation.
The RNA binding protein QKI5 suppresses ovarian cancer via downregulating transcriptional coactivator TAZ.
Loss-of-function missense variant of AKAP4 induced male infertility through reduced interaction with QRICH2 during sperm flagella development.
6-Thioguanine Inhibits Herpes Simplex Virus 1 Infection of Eyes.
Pan-cancer analysis of N4-acetylcytidine adaptor THUMPD1 as a predictor for prognosis and immunotherapy.
Heat stress affects fetal brain and intestinal function associated with the alterations of placental barrier in late pregnant mouse.
Responses of JNK signaling pathway to the toxic dinoflagellate Prorocentrum lima in the mussel Perna viridis.
Identification of key genes as predictive biomarkers for osteosarcoma metastasis using translational bioinformatics.
A machine learning pipeline revealing heterogeneous responses to drug perturbations on vascular smooth muscle cell spheroid morphology and formation.
Anti-tumor effect of polysaccharide from Pleurotus ostreatus on H22 mouse Hepatoma ascites in-vivo and hepatocellular carcinoma in-vitro model.
Pan-cancer multi-omics analyses reveal crosstalk between the Hippo and immune signaling pathways in the tumor microenvironment.
WITHDRAWN: Role of microRNA-19b-3p on osteoporosis after experimental spinal cord injury in rats.
A novel protoapigenone analog RY10-4 induces apoptosis of breast cancer cells by exacerbating mitochondrial Ca2+ influx through mitochondrial calcium uniporter.
miR-126 regulates angiogenesis in myocardial ischemia by targeting HIF-1α.
Synergistic anti-inflammatory activity of apigenin and curcumin co-encapsulated in caseins assessed with lipopolysaccharide-stimulated RAW 264.7 macrophages.
Intermittent bolus feeding does not enhance protein synthesis, myonuclear accretion, or lean growth more than continuous feeding in a premature piglet model.
Role of the hippo signaling pathway in the extracellular matrix degradation of chondrocytes induced by fluoride exposure.
Cypermethrin triggers YY1-mediated testosterone biosynthesis suppression.
Klotho ameliorated cognitive deficits in a temporal lobe epilepsy rat model by inhibiting ferroptosis.
Adipose-derived stem cells (ADSCs) inhibit the expression of anti-apoptosis proteins through up-regulation of ATF4 on breast cancer cells.
Glaucocalyxin A induces apoptosis and autophagy in tongue squamous cell carcinoma cells by regulating ROS.
IL-10 ameliorates PM2.5-induced lung injury by activating the AMPK/SIRT1/PGC-1α pathway.
Hsa-miR-34a-5p reverses multidrug resistance in gastric cancer cells by targeting the 3'-UTR of SIRT1 and inhibiting its expression.
CircZNF208 enhances the sensitivity to X-rays instead of carbon-ions through the miR-7-5p /SNCA signal axis in non-small-cell lung cancer cells.
Heat shock protein 90 inhibitor ameliorates pancreatic fibrosis by degradation of transforming growth factor-β receptor.
The Regulation of Neutrophil Extracellular Trap-induced Tissue Damage by Human CD177.
6-Shogaol from ginger shows anti-tumor effect in cervical carcinoma via PI3K/Akt/mTOR pathway.
microRNA-4429-5p suppresses the malignant development of colon cancer by targeting matrix metalloproteinase 16.
ROBO2 hampers malignant biological behavior and predicts a better prognosis in pancreatic adenocarcinoma.
Effect of electro-acupuncture at ST 36 on maternal food restriction-induced lung phenotype in rat offspring.
Comparison of the biological and functional characteristics of mesenchymal stem cells from intrahepatic and identical bone marrow.
Establishment of two homozygous CRISPR interference (CRISPRi) knock-in human induced pluripotent stem cell (hiPSC) lines for titratable endogenous gene repression.
Base editing-mediated perturbation of endogenous PKM1/2 splicing facilitates isoform-specific functional analysis in vitro and in vivo.
Loss of microRNA-147 function alleviates synovial inflammation through ZNF148 in rheumatoid and experimental arthritis.
DJ-1 activates the noncanonical NF-κB pathway via interaction with Cezanne to inhibit the apoptosis and promote the proliferation of Ishikawa cells.
Long noncoding RNA uc003pxg.1 regulates endothelial cell proliferation and migration via miR‑25‑5p in coronary artery disease.
Increased AT1 receptor expression mediates vasoconstriction leading to hypertension in Snx1-/- mice.
Downregulation of glucose-6-phosphatase expression contributes to fluoxetine-induced hepatic steatosis.
Chromium (VI) promotes EMT by regulating FLNA in BLCA.
Rearrangement of Actin Cytoskeleton by Zika Virus Infection Facilitates Blood-Testis Barrier Hyperpermeability.
Endothelial neuropilin-2 influences angiogenesis by regulating actin pattern development and α5-integrin-p-FAK complex recruitment to assembling adhesion sites.
Salidroside protects cardiac function in mice with diabetic cardiomyopathy via activation of mitochondrial biogenesis and SIRT3.
RNA m6A modification orchestrates a LINE-1-host interaction that facilitates retrotransposition and contributes to long gene vulnerability.
Inhibition of hepatitis E virus replication by zinc-finger antiviral Protein synergizes with IFN-β.
GINS2 promotes EMT in pancreatic cancer via specifically stimulating ERK/MAPK signaling.
Lys694Arg polymorphism leads to blunted responses to LPS by interfering TLR4 with recruitment of MyD88.
Genotype-dependent epigenetic regulation of DLGAP2 in alcohol use and dependence.
Helicobacter pylori induces gastric cancer via down-regulating miR-375 to inhibit dendritic cell maturation.
Vimentin rearrangement by phosphorylation is beneficial for porcine reproductive and respiratory syndrome virus replication in vitro.
EGCG synergizes the therapeutic effect of irinotecan through enhanced DNA damage in human colorectal cancer cells.
Ring finger protein 19A is overexpressed in non-small cell lung cancer and mediates p53 ubiquitin-degradation to promote cancer growth.
Propofol attenuates renal ischemia/reperfusion injury by regulating the MALAT1/miR-126-5p axis.
ASTE1 promotes shieldin-complex-mediated DNA repair by attenuating end resection.
Decreased TMEM40 expression is associated with malignant behavior of cutaneous squamous cell carcinoma and inhibits tumor progression.
Indoleamine 2,3-Dioxygenase 1 (IDO1) Promotes Cardiac Hypertrophy via a PI3K-AKT-mTOR-Dependent Mechanism.
A γ-adducin cleavage fragment induces neurite deficits and synaptic dysfunction in Alzheimer's disease.
Investigating the nature of active forces in tissues reveals how contractile cells can form extensile monolayers.
MiR-532-3p suppresses cell viability, migration and invasion of clear cell renal cell carcinoma through targeting TROAP.
Nitazoxanide impairs mitophagy flux through ROS-mediated mitophagy initiation and lysosomal dysfunction in bladder cancer.
Depletion of CIP2A inhibits the proliferation, migration, invasion and epithelial-mesenchymal transition of glioma cells.
The role of circTmeff-1 in incubation of context-induced morphine craving.
High-throughput screening and genome-wide analyses of 44 anticancer drugs in the 1000 Genomes cell lines reveals an association of the NQO1 gene with the response of multiple anticancer drugs.
PtdIns4P restriction by hydrolase SAC1 decides specific fusion of autophagosomes with lysosomes.
Classical swine fever virus infection suppresses claudin-1 expression to facilitate its replication in PK-15 cells.
Stabilization of Nrf2 leading to HO-1 activation protects against zinc oxide nanoparticles-induced endothelial cell death.
Bavachin enhances NLRP3 inflammasome activation induced by ATP or nigericin and causes idiosyncratic hepatotoxicity.
Expression of ISL1 and its partners in prostate cancer progression and neuroendocrine differentiation.
MD2 blockage prevents the migration and invasion of hepatocellular carcinoma cells via inhibition of the EGFR signaling pathway.
miR-744-5p suppresses tumor proliferation and metastasis by targeting transforming growth factor-beta 1 (TGF-β1) in hepatocellular carcinoma (HCC).
XPA serves as an autophagy and apoptosis inducer by suppressing hepatocellular carcinoma in a PI3K/Akt/mTOR dependent manner.
Vitamin D alleviates hypoxia/reoxygenation-induced injury of human trophoblast HTR-8 cells by activating autophagy.
TRIM27 contributes to glomerular endothelial cell injury in lupus nephritis by mediating the FoxO1 signaling pathway.
AHR mediates the aflatoxin B1 toxicity associated with hepatocellular carcinoma.
Bcl-2-associated transcription factor 1 Ser290 phosphorylation mediates DNA damage response and regulates radiosensitivity in gastric cancer.
Autophagy-associated circular RNA hsa_circ_0007813 modulates human bladder cancer progression via hsa-miR-361-3p/IGF2R regulation.
MiR-133a-3p inhibits scar formation in scalded mice and suppresses the proliferation and migration of scar derived-fibroblasts by targeting connective tissue growth factor.
miR-145-5p attenuates inflammatory response and apoptosis in myocardial ischemia-reperfusion injury by inhibiting (NADPH) oxidase homolog 1.
Cofilin-1 promotes fibrocyte differentiation and contributes to pulmonary fibrosis.
Human CD4+ T-Cell Clone Expansion Leads to the Expression of the Cysteine Peptidase Inhibitor Cystatin F.
RNA-binding protein RBM47 stabilizes IFNAR1 mRNA to potentiate host antiviral activity.
Rpsa Signaling Regulates Cortical Neuronal Morphogenesis via Its Ligand, PEDF, and Plasma Membrane Interaction Partner, Itga6.
The application of CRISPR/Cas9 system in cervical carcinogenesis.
PKCε controls the fusion of secretory vesicles in mast cells in a phosphatidic acid-dependent mode.
Pericentromeric noncoding RNA changes DNA binding of CTCF and inflammatory gene expression in senescence and cancer.
Tenascin-C Participates Pulmonary Injury Induced by Paraquat Through Regulating TLR4 and TGF-β Signaling Pathways.
UBE2T promotes autophagy via the p53/AMPK/mTOR signaling pathway in lung adenocarcinoma.
Enriched environment remedies cognitive dysfunctions and synaptic plasticity through NMDAR-Ca2+-Activin A circuit in chronic cerebral hypoperfusion rats.
AEG-1 silencing attenuates M2-polarization of glioma-associated microglia/macrophages and sensitizes glioma cells to temozolomide.
BGP-15 Inhibits Hyperglycemia-Aggravated VSMC Calcification Induced by High Phosphate.
Efficient intracellular delivery of proteins by a multifunctional chimaeric peptide in vitro and in vivo.
Autophagy Inhibition Plays a Protective Role in Ferroptosis Induced by Alcohol via the p62-Keap1-Nrf2 Pathway.
SESN2 protects against denervated muscle atrophy through unfolded protein response and mitophagy.
Biallelic SYNE2 Missense Mutations Leading to Nesprin-2 Giant Hypo-Expression Are Associated with Intellectual Disability and Autism.
Ten-eleven translocation 1 mediated-DNA hydroxymethylation is required for myelination and remyelination in the mouse brain.
Autophagic elimination of ribosomes during spermiogenesis provides energy for flagellar motility.
Helicobacter urease suppresses cytotoxic CD8+ T-cell responses through activating Myh9-dependent induction of PD-L1.
A single genetic locus controls both expression of DPEP1/CHMP1A and kidney disease development via ferroptosis.
Engineered basic fibroblast growth factor-overexpressing human umbilical cord-derived mesenchymal stem cells improve the proliferation and neuronal differentiation of endogenous neural stem cells and functional recovery of spinal cord injury by activating the PI3K-Akt-GSK-3β signaling pathway.
Sodium valproate increases activity of the sirtuin pathway resulting in beneficial effects for spinocerebellar ataxia-3 in vivo.
UHPLC-MS-based metabolomics and chemoinformatics study reveals the neuroprotective effect and chemical characteristic in Parkinson's disease mice after oral administration of Wen-Shen-Yang-Gan decoction.
Kaempferol attenuates diquat-induced oxidative damage and apoptosis in intestinal porcine epithelial cells.
Enhancer RNA m6A methylation facilitates transcriptional condensate formation and gene activation.
Repurposing of glycine transport inhibitors for the treatment of erythropoietic protoporphyria.
Gastrin exerts a protective effect against myocardial infarction via promoting angiogenesis.
Infection with Human Papillomavirus 18 Promotes Alkylating Agent-Induced Malignant Transformation in a Human Esophageal Cell Line.
Proof of Gene Doping in a Mouse Model with a Human Erythropoietin Gene Transferred Using an Adenoviral Vector.
Tubeimoside I protects against sepsis-induced cardiac dysfunction via SIRT3.
Silencing of RSPO1 mitigates obesity-related renal fibrosis in mice by deactivating Wnt/β-catenin pathway.
Long-term exposure to environmental level of phenanthrene causes adaptive immune response and fibrosis in mouse kidneys.
Itpr1 regulates the formation of anterior eye segment tissues derived from neural crest cells.
HPV16 E6 enhances the radiosensitivity in HPV-positive human head and neck squamous cell carcinoma by regulating the miR-27a-3p/SMG1 axis.
Targeted Ablation of Primary Cilia in Differentiated Dopaminergic Neurons Reduces Striatal Dopamine and Responsiveness to Metabolic Stress.
Loss of Smad4 promotes aggressive lung cancer metastasis by de-repression of PAK3 via miRNA regulation.
Inhibition of DNA methylation de-represses peroxisome proliferator-activated receptor-γ and attenuates pulmonary fibrosis.
Serum exosomal pregnancy zone protein as a promising biomarker in inflammatory bowel disease.
Rab1A promotes cell proliferation and migration by upregulating Gli1 in colorectal cancer.
The Cell-Permeable Derivative of the Immunoregulatory Metabolite Itaconate, 4-Octyl Itaconate, Is Anti-Fibrotic in Systemic Sclerosis.
Humanin Alleviates Insulin Resistance in Polycystic Ovary Syndrome: A Human and Rat Model-Based Study.
TSH Activates Macrophage Inflammation by G13- and G15-dependent Pathways.
LncRNA ABCC6P1 promotes proliferation and migration of papillary thyroid cancer cells via Wnt/β-catenin signaling pathway.
ESM1 promotes triple-negative breast cancer cell proliferation through activating AKT/NF-κB/Cyclin D1 pathway.
hucMSCs transplantation promotes locomotor function recovery, reduces apoptosis and inhibits demyelination after SCI in rats.
Ginsenoside-Rg1 acts as an IDO1 inhibitor, protects against liver fibrosis via alleviating IDO1-mediated the inhibition of DCs maturation.
Bergenin inhibits bladder cancer progression via activating the PPARγ/PTEN/Akt signal pathway.
Arsenic-induced autophagy regulates apoptosis in AML-12 cells.
LncRNA XIST Promotes Migration and Invasion of Papillary Thyroid Cancer Cell by Modulating MiR-101-3p/CLDN1 Axis.
Mutant IDH1 Enhances Temozolomide Sensitivity via Regulation of the ATM/CHK2 Pathway in Glioma.
Morusin inhibits the growth of human colorectal cancer HCT116‑derived sphere‑forming cells via the inactivation of Akt pathway.
Mono-macrophage-Derived MANF Protects Against Lipopolysaccharide-Induced Acute Kidney Injury via Inhibiting Inflammation and Renal M1 Macrophages.
Aspergillus fumigatus-Stimulated Human Corneal Epithelial Cells Induce Pyroptosis of THP-1 Macrophages by Secreting TSLP.
MiR-32-5p knockdown inhibits epithelial to mesenchymal transition and renal fibrosis by targeting SMAD7 in diabetic nephropathy.
Cartilage endplate stem cells inhibit intervertebral disc degeneration by releasing exosomes to nucleus pulposus cells to activate Akt/autophagy.
LRP6 downregulation promotes cardiomyocyte proliferation and heart regeneration.
A chemical genetics approach to examine the functions of AAA proteins.
Programmed cell death 4 modulates lysosomal function by inhibiting TFEB translation.
Small molecule screening identified cepharanthine as an inhibitor of porcine reproductive and respiratory syndrome virus infection in vitro by suppressing integrins/ILK/RACK1/PKCα/NF-κB signalling axis.
Characterization of an endoplasmic reticulum stress-related signature to evaluate immune features and predict prognosis in glioma.
ARID1B/SUB1-activated lncRNA HOXA-AS2 drives the malignant behaviour of hepatoblastoma through regulation of HOXA3.
Helicobacter pylori inhibits autophagic flux and promotes its intracellular survival and colonization by down-regulating SIRT1.
Glucagon-like peptide 2 attenuates intestinal mucosal barrier injury through the MLCK/pMLC signaling pathway in a piglet model.
Ten-m/Odz3 regulates migration and differentiation of chondrogenic ATDC5 cells via RhoA-mediated actin reorganization.
Involvement of oxidative stress-induced annulus fibrosus cell and nucleus pulposus cell ferroptosis in intervertebral disc degeneration pathogenesis.
Novel role of CXCL14 in modulating STAR expression in luteinized granulosa cells: implication for progesterone synthesis in PCOS patients.
Melatonin exerts protective effects on diabetic retinopathy via inhibition of Wnt/β-catenin pathway as revealed by quantitative proteomics.
Depression-like behavior is associated with lower Per2 mRNA expression in the lateral habenula of rats.
MNK as a potential pharmacological target for suppressing LPS-induced acute lung injury in mice.
Harmine alleviates atherogenesis by inhibiting disturbed flow-mediated endothelial activation via protein tyrosine phosphatase PTPN14 and YAP.
A novel amphibian-derived peptide alleviated ultraviolet B-induced photodamage in mice.
Effects of miR-132-3p on progress and epithelial mesenchymal transition of non-small cell lung cancer via regulating KLF7.
POST1/C12ORF49 regulates the SREBP pathway by promoting site-1 protease maturation.
Transcription factor EB promotes rheumatoid arthritis of Sprague-Dawley rats via regulating autophagy.
DBA/1 mice display equivalent cardiac function to C57BL/6J mice.
A partial loss-of-function variant in GNRNR gene in a Chinese cohort with idiopathic hypogonadotropic hypogonadism.
PolyQ-expanded proteins impair cellular proteostasis of ataxin-3 through sequestering the co-chaperone HSJ1 into aggregates.
ATP6V0A1 encoding the a1-subunit of the V0 domain of vacuolar H+-ATPases is essential for brain development in humans and mice.
Therapeutic Effect of Endothelin-Converting Enzyme Inhibitor on Chronic Kidney Disease through the Inhibition of Endoplasmic Reticulum Stress and the NLRP3 Inflammasome.
Fangchinoline suppresses conjunctival melanoma by directly binding FUBP2 and inhibiting the homologous recombination pathway.
DOCK7 protects against replication stress by promoting RPA stability on chromatin.
MCPIP1-mediated NFIC alternative splicing inhibits proliferation of triple-negative breast cancer via cyclin D1-Rb-E2F1 axis.
Regulation of MRP4 Expression by circHIPK3 via Sponging miR-124-3p/miR-4524-5p in Hepatocellular Carcinoma.
ARID3A promotes the development of colorectal cancer by upregulating AURKA.
Anti-tumor activity of a novel proteasome inhibitor D395 against multiple myeloma and its lower cardiotoxicity compared with carfilzomib.
The role of E26 transformation-specific variant transcription factor 5 in colorectal cancer cell proliferation and cell cycle progression.
TRIM25 activates AKT/mTOR by inhibiting PTEN via K63-linked polyubiquitination in non-small cell lung cancer.
Interleukin-17A mediates tobacco smoke-induced lung cancer epithelial-mesenchymal transition through transcriptional regulation of ΔNp63α on miR-19.
Multi-omics analysis to identify susceptibility genes for colorectal cancer.
Knockdown of the Ribosomal Protein eL38 in HEK293 Cells Changes the Translational Efficiency of Specific Genes.
Divergent immunometabolic changes in adipose tissue and skeletal muscle with ageing in healthy humans.
ZIP8 mediates the extracellular matrix degradation of nucleus pulposus cells via NF-κB signaling pathway.
Abelson interactor 1 splice isoform-L plays an anti-oncogenic role in colorectal carcinoma through interactions with WAVE2 and full-length Abelson interactor 1.
Impaired 26S Proteasome Assembly Precedes Neuronal Loss in Mutant UBQLN2 Rats.
Generation of a Polyclonal Antibody against the Mouse Metal Transporter ZIP8.
Inhibition of Notch1 signaling reduces hepatocyte injury in nonalcoholic fatty liver disease via autophagy.
Role of Small Envelope Protein in Sustaining the Intracellular and Extracellular Levels of Hepatitis B Virus Large and Middle Envelope Proteins.
Ubiquitin-specific peptidase 39 promotes human glioma cells migration and invasion by facilitating ADAM9 mRNA maturation.
CircLIFR synergizes with MSH2 to attenuate chemoresistance via MutSα/ATM-p73 axis in bladder cancer.
RUNX1 promotes MAPK signaling to increase tumor progression and metastasis via OPN in head and neck cancer.
miR-324-3p reverses cisplatin resistance by inducing GPX4-mediated ferroptosis in lung adenocarcinoma cell line A549.
Crystal structures reveal a novel dimer of the RWD domain of human general control nonderepressible 2.
Promyelocytic leukemia protein promotes the phenotypic switch of smooth muscle cells in atherosclerotic plaques of human coronary arteries.
Effects of CMYA1 overexpression on cardiac structure and function in mice.
Dual effects of fibrinogen decoration on the tuning of silica nanoparticles-induced autophagic response: The implication of sedimentation and internalization.
Chemoproteomics-enabled discovery of covalent RNF114-based degraders that mimic natural product function.
Glaucocalyxin A induces cell cycle arrest and apoptosis via inhibiting NF-κB/p65 signaling pathway in melanoma cells.
Synthesis, characterization, and targeted chemotherapy of SCT200-linker-monomethyl auristatin E conjugates.
The biological function and clinical significance of STIL in osteosarcoma.
Loss of Mitochondrial Protease CLPP Activates Type I IFN Responses through the Mitochondrial DNA-cGAS-STING Signaling Axis.
AKR1B10 negatively regulates autophagy through reducing GAPDH upon glucose starvation in colon cancer.
KLF7/VPS35 axis contributes to hepatocellular carcinoma progression through CCDC85C-activated β-catenin pathway.
Cytoplasmic DNA sensing by KU complex in aged CD4+ T cell potentiates T cell activation and aging-related autoimmune inflammation.
TDP-43 prevents endogenous RNAs from triggering a lethal RIG-I-dependent interferon response.
Changes in hepatic triglyceride content with the activation of ER stress and increased FGF21 secretion during pregnancy.
EpCAM promotes endosomal modulation of the cortical RhoA zone for epithelial organization.
Inflammatory Injury and Mitophagy in the Cock Heart Induced by the Oral Administration of Hexavalent Chromium.
TRIM39 deficiency inhibits tumor progression and autophagic flux in colorectal cancer via suppressing the activity of Rab7.
Reciprocal regulation of RIG-I and XRCC4 connects DNA repair with RIG-I immune signaling.
ADAMTS19 Suppresses Cell Migration and Invasion by Targeting S100A16 via the NF-κB Pathway in Human Gastric Cancer.
NET1 promotes HCC growth and metastasis in vitro and in vivo via activating the Akt signaling pathway.
p53-targeted lncRNA ST7-AS1 acts as a tumour suppressor by interacting with PTBP1 to suppress the Wnt/β-catenin signalling pathway in glioma.
Dcaf11 activates Zscan4-mediated alternative telomere lengthening in early embryos and embryonic stem cells.
Polychlorinated biphenyl quinone regulates MLKL phosphorylation that stimulates exosome biogenesis and secretion via a short negative feedback loop.
Design and screening of a novel neuropilin-1 targeted penetrating peptide for anti-angiogenic therapy in glioma.
MicroRNA-376b-5p targets SOX7 to alleviate ischemic brain injury in a mouse model through activating Wnt/β-catenin signaling pathway.
RANK promotes colorectal cancer migration and invasion by activating the Ca2+-calcineurin/NFATC1-ACP5 axis.
Identification of Beilschmiedia tsangii Root Extract as a Liver Cancer Cell-Normal Keratinocyte Dual-Selective NRF2 Regulator.
Lycopene alleviates oxidative stress via the PI3K/Akt/Nrf2pathway in a cell model of Alzheimer's disease.
Conditioned medium from M2b macrophages modulates the proliferation, migration, and apoptosis of pulmonary artery smooth muscle cells by deregulating the PI3K/Akt/FoxO3a pathway.
Icariin protects against sodium azide-induced neurotoxicity by activating the PI3K/Akt/GSK-3β signaling pathway.
Glycyrrhizin suppresses epithelial-mesenchymal transition by inhibiting high-mobility group box1 via the TGF-β1/Smad2/3 pathway in lung epithelial cells.
miR-29a-3p directly targets Smad nuclear interacting protein 1 and inhibits the migration and proliferation of cervical cancer HeLa cells.
Examination of the Effect of a 50-Hz Electromagnetic Field at 500 μT on Parameters Related With the Cardiovascular System in Rats.
Mimicking the Organic and Inorganic Composition of Anabolic Bone Enhances Human Mesenchymal Stem Cell Osteoinduction and Scaffold Mechanical Properties.
Histone Deacetylases Inhibit the Snail2-Mediated EMT During Metastasis of Hepatocellular Carcinoma Cells.
RNA-Binding Protein HuR Suppresses Inflammation and Promotes Extracellular Matrix Homeostasis via NKRF in Intervertebral Disc Degeneration.
Knockdown of POSTN Inhibits Osteogenic Differentiation of Mesenchymal Stem Cells From Patients With Steroid-Induced Osteonecrosis.
Caspase-8 Inhibition Prevents the Cleavage and Degradation of E3 Ligase Substrate Receptor Cereblon and Potentiates Its Biological Function.
HDAC6 Regulates the Fusion of Autophagosome and Lysosome to Involve in Odontoblast Differentiation.
Transient Receptor Potential Channel 6 Knockout Ameliorates Kidney Fibrosis by Inhibition of Epithelial-Mesenchymal Transition.
Iron Overload Is Associated With Accelerated Progression of Osteoarthritis: The Role of DMT1 Mediated Iron Homeostasis.
miR-766-3p Targeting BCL9L Suppressed Tumorigenesis, Epithelial-Mesenchymal Transition, and Metastasis Through the β-Catenin Signaling Pathway in Osteosarcoma Cells.
Deficiency of LMP10 Attenuates Diet-Induced Atherosclerosis by Inhibiting Macrophage Polarization and Inflammation in Apolipoprotein E Deficient Mice.
p.His16Arg of STXBP1 (MUNC18-1) Associated With Syntaxin 3B Causes Autosomal Dominant Congenital Nystagmus.
EZH2-Inhibited MicroRNA-454-3p Promotes M2 Macrophage Polarization in Glioma.
Modulation of Increased mGluR1 Signaling by RGS8 Protects Purkinje Cells From Dendritic Reduction and Could Be a Common Mechanism in Diverse Forms of Spinocerebellar Ataxia.
MicroRNA-221/222 Mediates ADSC-Exosome-Induced Cardioprotection Against Ischemia/Reperfusion by Targeting PUMA and ETS-1.
Glycogen Phosphorylase B Is Regulated by miR101-3p and Promotes Hepatocellular Carcinoma Tumorigenesis.
Oct4 Regulates the Transition of Cancer Stem-Like Cells to Tumor Endothelial-Like Cells in Human Liver Cancer.
Overexpression of FAM46A, a Non-canonical Poly(A) Polymerase, Promotes Hemin-Induced Hemoglobinization in K562 Cells.
Siwei Jianbu decoction improves painful paclitaxel-induced peripheral neuropathy in mouse model by modulating the NF-κB and MAPK signaling pathways.
The Changes of Twist1 Pathway in Pulmonary Microvascular Permeability in a Newborn Rat Model of Hyperoxia-Induced Acute Lung Injury.
CDKN2a/p16 Antagonizes Hepatic Stellate Cell Activation and Liver Fibrosis by Modulating ROS Levels.
Crx Is Posttranscriptionally Regulated by Light Stimulation in Postnatal Rat Retina.
S-Adenosylmethionine Alleviates Amyloid-β-Induced Neural Injury by Enhancing Trans-Sulfuration Pathway Activity in Astrocytes.
Dendrobium nobile Lindl. Alkaloids Ameliorate Cognitive Dysfunction in Senescence Accelerated SAMP8 Mice by Decreasing Amyloid-β Aggregation and Enhancing Autophagy Activity.
Oxytocin Alleviates MPTP-Induced Neurotoxicity in Mice by Targeting MicroRNA-26a/Death-Associated Protein Kinase 1 Pathway.
miR-193a-3p Mediates Placenta Accreta Spectrum Development by Targeting EFNB2 via Epithelial-Mesenchymal Transition Pathway Under Decidua Defect Conditions.
DGCR8/miR-106 Axis Enhances Radiosensitivity of Head and Neck Squamous Cell Carcinomas by Downregulating RUNX3.
Identification of Transcriptional Variation in Aortic Remodeling Using a Murine Transverse Aortic Constriction (TAC) Model.
Dioscin Protects against Aβ1-42 Oligomers-Induced Neurotoxicity via the Function of SIRT3 and Autophagy.
Osthole: A Traditional Chinese Medicine for Ocular Anti-Angiogenic Therapy.
Electroacupuncture Improves Motor Symptoms of Parkinson's Disease and Promotes Neuronal Autophagy Activity in Mouse Brain.
Overexpression of MECP2 attenuates cigarette smoke extracts induced lung epithelial cell injury by promoting CYP1B1 methylation.
TRIB3 promotes hepatocellular carcinoma growth and predicts poor prognosis.
BMSC-derived leptin and IGFBP2 promote erlotinib resistance in lung adenocarcinoma cells through IGF-1R activation in hypoxic environment.
DLX6-AS1 promotes cell proliferation, migration and EMT of gastric cancer through FUS-regulated MAP4K1.
Effect of Wenshen-Yanggan Decoction on Movement Disorder and Substantia Nigra Dopaminergic Neurons in Mice with Chronic Parkinson's Disease.
Adrenal (Pro)renin Receptor Expression and Serum Soluble (Pro)renin Receptor Concentration in Primary Aldosteronism.
Autophagy Contributes to Host Immunity and Protection against Zika Virus Infection via Type I IFN Signaling.
Distinct Expression Patterns of Apoptosis and Autophagy-Associated Proteins and Genes during Postnatal Development of Spiral Ganglion Neurons in Rat.
Citron Rho-Interacting Serine/Threonine Kinase Promotes HIF1a-CypA Signaling and Growth of Human Pancreatic Adenocarcinoma.
Electroacupuncture Improved Chronic Cerebral Hypoperfusion-Induced Anxiety-Like Behavior and Memory Impairments in Spontaneously Hypertensive Rats by Downregulating the ACE/Ang II/AT1R Axis and Upregulating the ACE2/Ang-(1-7)/MasR Axis.
PBX3 Promotes Tumor Growth and Angiogenesis via Activation of AT1R/VEGFR2 Pathway in Papillary Thyroid Carcinoma.
AURKA Increase the Chemosensitivity of Colon Cancer Cells to Oxaliplatin by Inhibiting the TP53-Mediated DNA Damage Response Genes.
Jian-Pi-Yi-Shen Regulates EPO and Iron Recycling Protein Expressions in Anemic Rats with Chronic Kidney Disease: Accumulation of Hypoxia Inducible Factor-2α via ERK Signaling.
Exosomes from Bone Marrow Microenvironment-Derived Mesenchymal Stem Cells Affect CML Cells Growth and Promote Drug Resistance to Tyrosine Kinase Inhibitors.
Responsive Expression of MafF to β-Amyloid-Induced Oxidative Stress.
EA Ameliorated Depressive Behaviors in CUMS Rats and Was Related to Its Suppressing Autophagy in the Hippocampus.
Metformin Reduces the Senescence of Renal Tubular Epithelial Cells in Diabetic Nephropathy via the MBNL1/miR-130a-3p/STAT3 Pathway.
Fuzheng Huayu Recipe Prevented and Treated CCl4-Induced Mice Liver Fibrosis through Regulating Polarization and Chemotaxis of Intrahepatic Macrophages via CCL2 and CX3CL1.
Trained Innate Immunity by Repeated Low-Dose Lipopolysaccharide Injections Displays Long-Term Neuroprotective Effects.
Astaxanthin Protects Ochratoxin A-Induced Oxidative Stress and Apoptosis in the Heart via the Nrf2 Pathway.
Rhein Suppresses Neuroinflammation via Multiple Signaling Pathways in LPS-Stimulated BV2 Microglia Cells.
Adaptive Autophagy Offers Cardiorenal Protection in Rats with Acute Myocardial Infarction.
Anticancer Activity of Tetrandrine by Inducing Apoptosis in Human Breast Cancer Cell Line MDA-MB-231 In Vivo.
Tumor Necrosis Factor Receptor-Associated Protein 1 Protects against Mitochondrial Injury by Preventing High Glucose-Induced mPTP Opening in Diabetes.
Curcumin Inhibits Proliferation and Epithelial-Mesenchymal Transition in Lens Epithelial Cells through Multiple Pathways.
Mild Hypothermia Attenuates Hepatic Ischemia-Reperfusion Injury through Regulating the JAK2/STAT3-CPT1a-Dependent Fatty Acid β-Oxidation.
Plumbagin Enhances the Anticancer Efficacy of Cisplatin by Increasing Intracellular ROS in Human Tongue Squamous Cell Carcinoma.
NLRC3 Delays the Progression of AD in APP/PS1 Mice via Inhibiting PI3K Activation.
Protective Effect of Simplicillium sp. Ethyl Acetate Extract against High Glucose-Induced Oxidative Stress in HUVECs.
The Class III PI3K/Beclin-1 Autophagic Pathway Participates in the mmLDL-Induced Upregulation of ETA Receptor in Mouse Mesenteric Arteries.
Nei Endonuclease VIII-Like1 (NEIL1) Inhibits Apoptosis of Human Colorectal Cancer Cells.
Baicalin Ameliorates Cognitive Impairment and Protects Microglia from LPS-Induced Neuroinflammation via the SIRT1/HMGB1 Pathway.
Saponin from Periploca forrestii Schltr Mitigates Oxazolone-Induced Atopic Dermatitis via Modulating Macrophage Activation.
Roux-en-Y Gastric Bypass in Obese Diabetic Rats Promotes Autophagy to Improve Lipid Metabolism through mTOR/p70S6K Signaling Pathway.
Obesity-Induced Upregulation of ZBTB7A Promotes Lipid Accumulation through SREBP1.
Mining the Prognostic Value of HNRNPAB and Its Function in Breast Carcinoma.
Protective Role of Tangshen Formula on the Progression of Renal Damage in db/db Mice by TRPC6/Talin1 Pathway in Podocytes.
Tianma Gouteng Decoction Exerts Cardiovascular Protection by Upregulating OPG and TRAIL in Spontaneously Hypertensive Rats.
Quantitative Analysis of the Proteome and the Succinylome in the Thyroid Tissue of High-Fat Diet-Induced Hypothyroxinemia in Rats.
Prokineticin 2 (PK2) Rescues Cardiomyocytes from High Glucose/High Palmitic Acid-Induced Damage by Regulating the AKT/GSK3β Pathway In Vitro.
Anticancer Activity of Modified Tongyou Decoction on Eca109 Esophageal Cancer Cell Invasion and Metastasis through Regulation of the Epithelial-Mesenchymal Transition Mediated by the HIF-1α-Snail Axis.
GDF15 Repression Contributes to 5-Fluorouracil Resistance in Human Colon Cancer by Regulating Epithelial-Mesenchymal Transition and Apoptosis.
Ginsenoside Rg1 Alleviates Podocyte Injury Induced by Hyperlipidemia via Targeting the mTOR/NF-κB/NLRP3 Axis.
RRS1 Promotes Retinoblastoma Cell Proliferation and Invasion via Activating the AKT/mTOR Signaling Pathway.
Posttranslational Modification Defects in Fibroblast Growth Factor Receptor 1 as a Reason for Normosmic Isolated Hypogonadotropic Hypogonadism.
OSCC Exosomes Regulate miR-210-3p Targeting EFNA3 to Promote Oral Cancer Angiogenesis through the PI3K/AKT Pathway.
Lipin1 Is Involved in the Pathogenesis of Diabetic Encephalopathy through the PKD/Limk/Cofilin Signaling Pathway.
Silencing of PRDX2 Inhibits the Proliferation and Invasion of Non-Small Cell Lung Cancer Cells.
Vagus Nerve Stimulation Alleviates Hepatic Ischemia and Reperfusion Injury by Regulating Glutathione Production and Transformation.
ADAM10 promotes cell growth, migration, and invasion in osteosarcoma via regulating E-cadherin/β-catenin signaling pathway and is regulated by miR-122-5p.
MYC-regulated lncRNA NEAT1 promotes B cell proliferation and lymphomagenesis via the miR-34b-5p-GLI1 pathway in diffuse large B-cell lymphoma.
Alantolactone inhibits cell autophagy and promotes apoptosis via AP2M1 in acute lymphoblastic leukemia.
A novel chalcone derivative has antitumor activity in melanoma by inducing DNA damage through the upregulation of ROS products.
Downexpression of HSD17B6 correlates with clinical prognosis and tumor immune infiltrates in hepatocellular carcinoma.
EphA5 knockdown enhances the invasion and migration ability of esophageal squamous cell carcinoma via epithelial-mesenchymal transition through activating Wnt/β-catenin pathway.
MicroRNA-196b-5p promotes malignant progression of colorectal cancer by targeting ING5.
IL-21 promotes osteoblastic differentiation of human valvular interstitial cells through the JAK3/STAT3 pathway.
Interactome analysis of gene expression profiles identifies CDC6 as a potential therapeutic target modified by miR-215-5p in hepatocellular carcinoma.
Fine Particulate Matter (PM2.5) upregulates expression of Inflammasome NLRP1 via ROS/NF-κB signaling in HaCaT Cells.
Retinal dehydrogenase 5 (RHD5) attenuates metastasis via regulating HIPPO/YAP signaling pathway in Hepatocellular Carcinoma.
Polysaccharide extracted from WuGuChong reduces high-fat diet-induced obesity in mice by regulating the composition of intestinal microbiota.
Human follicular fluid proteome reveals association between overweight status and oocyte maturation abnormality.
Wnt5a/CaMKII/ERK/CCL2 axis is required for tumor-associated macrophages to promote colorectal cancer progression.
Cdh1 functions as an oncogene by inducing self-renewal of lung cancer stem-like cells via oncogenic pathways.
Poly(U) binding splicing factor 60 promotes renal cell carcinoma growth by transcriptionally upregulating telomerase reverse transcriptase.
Glucocorticoids improve severe or critical COVID-19 by activating ACE2 and reducing IL-6 levels.
MFP-FePt-GO Nanocomposites Promote Radiosensitivity of Non-Small Cell Lung Cancer Via Activating Mitochondrial-Mediated Apoptosis and Impairing DNA Damage Repair.
Polysaccharides isolated from Cordyceps Sinensis contribute to the progression of NASH by modifying the gut microbiota in mice fed a high-fat diet.
Effects of miR-103 by negatively regulating SATB2 on proliferation and osteogenic differentiation of human bone marrow mesenchymal stem cells.
Decorin knockdown affects the gene expression profile of adhesion, growth and extracellular matrix metabolism in C-28/I2 chondrocytes.
S100A6 promotes proliferation and migration of HepG2 cells via increased ubiquitin-dependent degradation of p53.
TiO2 Nanoparticles Caused DNA Damage in Lung and Extra-Pulmonary Organs Through ROS-Activated FOXO3a Signaling Pathway After Intratracheal Administration in Rats.
Anticancer Effects of Zinc Oxide Nanoparticles Through Altering the Methylation Status of Histone on Bladder Cancer Cells.
Cardiac-Specific Caveolin-3 Overexpression Prevents Post-Myocardial Infarction Ventricular Arrhythmias by Inhibiting Ryanodine Receptor-2 Hyperphosphorylation.
Upregulation of C Terminus of Hsc70-Interacting Protein Attenuates Apoptosis and Procoagulant Activity and Facilitates Brain Repair After Traumatic Brain Injury.
Oxymatrine Liposomes for Intervertebral Disc Treatment: Formulation, in vitro and vivo Assessments.
Plasmacytoid Dendritic Cells Protect Against Middle Cerebral Artery Occlusion Induced Brain Injury by Priming Regulatory T Cells.
Neuroprotection Against Parkinson's Disease Through the Activation of Akt/GSK3β Signaling Pathway by Tovophyllin A.
Neuroprotective Effect of Ketone Metabolism on Inhibiting Inflammatory Response by Regulating Macrophage Polarization After Acute Cervical Spinal Cord Injury in Rats.
Effects of Saikosaponin D on CYP1A2 and CYP2D6 in HepaRG Cells.
Combined Transplantation of Olfactory Ensheathing Cells With Rat Neural Stem Cells Enhanced the Therapeutic Effect in the Retina of RCS Rats.
Effect of Platelet-Activating Factor on Barrier Function of ARPE-19 Cells.
Metformin Inhibits Propofol-Induced Apoptosis of Mouse Hippocampal Neurons HT-22 Through Downregulating Cav-1.
Bergenin Exerts Hepatoprotective Effects by Inhibiting the Release of Inflammatory Factors, Apoptosis and Autophagy via the PPAR-γ Pathway.
RGFP966 Suppresses Tumor Growth and Migration Through Inhibition of EGFR Expression in Hepatocellular Carcinoma Cells in vitro.
Cigarette smoke supports stemness and epithelial-mesenchymal transition in bladder cancer stem cells through SHH signaling.
Combination of astragaloside IV and ACEi ameliorates renal injuries in db/db mice.
FOXO1 and hsa-microRNA-204-5p affect the biologic behavior of MDA-MB-231 breast cancer cells.
Kin17 knockdown suppresses the migration and invasion of cervical cancer cells through NF-κB-Snail pathway.
Kelch-like protein 14 promotes proliferation and migration of ovarian cancer cells.
Overexpression of EPDR1 has an antitumorigenic effect on breast cancer in vitro.
Clinical significance of focal adhesion kinase (FAK) in cervical cancer progression and metastasis.
MicroRNA-451a targets caveolin-1 in stomach cancer cells.
Effect of the SIRT3-AMPK/PPAR pathway on invasion and migration of cervical cancer cells.
Acupuncture Targeting SIRT1 in the Hypothalamic Arcuate Nucleus Can Improve Obesity in High-Fat-Diet-Induced Rats with Insulin Resistance via an Anorectic Effect.
Circular RNA circNELL2 Acts as the Sponge of miR-127-5p to Promote Esophageal Squamous Cell Carcinoma Progression.
TDO Promotes Hepatocellular Carcinoma Progression.
TMED3 Promotes Proliferation and Migration in Breast Cancer Cells by Activating Wnt/β-Catenin Signaling.
Characterization of Triple-Negative Breast Cancer MDA-MB-231 Cell Spheroid Model.
β-Elemene Enhances the Chemotherapeutic Effect of 5-Fluorouracil in Triple-Negative Breast Cancer via PI3K/AKT, RAF-MEK-ErK, and NF-κB Signaling Pathways.
Diosgenin and GSK126 Produce Synergistic Effects on Epithelial-Mesenchymal Transition in Gastric Cancer Cells by Mediating EZH2 via the Rho/ROCK Signaling Pathway.
Comprehensive Transcriptomic Analysis and Experimental Validation Identify lncRNA HOXA-AS2/miR-184/COL6A2 as the Critical ceRNA Regulation Involved in Low-Grade Glioma Recurrence.
miR-877-5p Suppresses Gastric Cancer Cell Proliferation Through Targeting FOXM1.
FANCI Cooperates with IMPDH2 to Promote Lung Adenocarcinoma Tumor Growth via a MEK/ERK/MMPs Pathway.
DNMT1 Enhances the Radiosensitivity of HPV-Positive Head and Neck Squamous Cell Carcinomas via Downregulating SMG1.
Microsatellite Instability-Related ACVR2A Mutations Partially Account for Decreased Lymph Node Metastasis in MSI-H Gastric Cancers.
GPR30 Promotes the Phenotypic Switching of Vascular Smooth Muscle Cells via Activating the AKT and ERK Pathways.
Low-Dose Radiation Promotes Invasion and Migration of A549 Cells by Activating the CXCL1/NF-κB Signaling Pathway.
Cbl Proto-Oncogene B (CBLB) c.197A>T Mutation Induces Mild Metabolic Dysfunction in Partial Type I Multiple Symmetric Lipomatosis (MSL).
RCC2 Interacts with Small GTPase RalA and Regulates Cell Proliferation and Motility in Gastric Cancer.
RSF-1 siRNA Enhances Tumor Radiosensitivity in Cervical Cancer via Enhanced DNA Damage, Cell Cycle Redistribution, and Promotion of Apoptosis.
Long Non-Coding RNA SPRY4-IT1 Reverses Cisplatin Resistance by Downregulating MPZL-1 via Suppressing EMT in NSCLC.
Tumor Suppressor microRNA-138 Suppresses Low-Grade Glioma Development and Metastasis via Regulating IGF2BP2.
Circular RNA 0001313 Knockdown Suppresses Non-Small Cell Lung Cancer Cell Proliferation and Invasion via the microRNA-452/HMGB3/ERK/MAPK Axis.
Knockdown of Circular RNA Hsa_circ_0000714 Can Regulate RAB17 by Sponging miR-370-3p to Reduce Paclitaxel Resistance of Ovarian Cancer Through CDK6/RB Pathway.
DUSP9 Suppresses Proliferation and Migration of Clear Cell Renal Cell Carcinoma via the mTOR Pathway.
Hsa_circRNA_100146 Acts as a Sponge of miR-149-5p in Promoting Bladder Cancer Progression via Regulating RNF2.
Overexpression of RNF126 Promotes the Development of Colorectal Cancer via Enhancing p53 Ubiquitination and Degradation.
17-Allylamino-Demethoxygeldanamycin Ameliorate Microthrombosis Via HSP90/RIP3/NLRP3 Pathway After Subarachnoid Hemorrhage in Rats.
lncRNA USP2-AS1 promotes colon cancer progression by modulating Hippo/YAP1 signaling.
β-catenin regulates myocardial ischemia/reperfusion injury following heterotopic heart transplantation in mice by modulating PTEN pathways.
Homocysteine-induced electrical remodeling via the mediation of IP3R1/Nav1.5 signaling pathway.
Astragaloside IV alleviates puromycin aminonucleoside-induced podocyte cytoskeleton injury through the Wnt/PCP pathway.
CircAPLP2 regulates the proliferation and metastasis of colorectal cancer by targeting miR-101-3p to activate the Notch signalling pathway.
Huangqi-Danshen decoction alleviates diabetic nephropathy in db/db mice by inhibiting PINK1/Parkin-mediated mitophagy.
Kaempferol attenuated cisplatin-induced cardiac injury via inhibiting STING/NF-κB-mediated inflammation.
Enzastaurin enhances ATRA-induced differentiation of acute myeloid leukemia cells.
Polydopamine coating with static magnetic field promotes the osteogenic differentiation of human bone-derived mesenchymal stem cells on three-dimensional printed porous titanium scaffolds by upregulation of the BMP-Smads signaling pathway.
EphA5 Silencing Increases the Radiosensitivity of ESCC Cells Through ATM-Dependent Pathway.
miR-758-3p Inhibits Proliferation, Migration, and Invasion of Clear Cell Renal Cell Carcinoma and Predicts Favorable Prognosis.
Exosome-Reversed Chemoresistance to Cisplatin in Non-Small Lung Cancer Through Transferring miR-613.
miR-31-5p Regulates 14-3-3 ɛ to Inhibit Prostate Cancer 22RV1 Cell Survival and Proliferation via PI3K/AKT/Bcl-2 Signaling Pathway.
MiTF is Associated with Chemoresistance to Cisplatin in A549 Lung Cancer Cells via Modulating Lysosomal Biogenesis and Autophagy.
Class I HDAC Inhibitor Improves Synaptic Proteins and Repairs Cytoskeleton Through Regulating Synapse-Related Genes In vitro and In vivo.
FTY720 Prevents Spatial Memory Impairment in a Rat Model of Chronic Cerebral Hypoperfusion via a SIRT3-Independent Pathway.
The Requirement of the C-Terminal Domain of GluA1 in Different Forms of Long-Term Potentiation in the Hippocampus Is Age-Dependent.
Glucosamine-6-Phosphate Isomerase 1 Promotes Tumor Progression and Indicates Poor Prognosis in Hepatocellular Carcinoma.
Down-regulation of USP8 Inhibits Cholangiocarcinoma Cell Proliferation and Invasion.
AOC1 Contributes to Tumor Progression by Promoting the AKT and EMT Pathways in Gastric Cancer.
MicroRNA-1276 Promotes Colon Cancer Cell Proliferation by Negatively Regulating LACTB.
Hyperin Controls the Development and Therapy of Gastric Cancer via Regulating Wnt/β-Catenin Signaling.
MicroRNA-802 Suppresses Tumorigenesis of Colorectal Cancer via Regulating UBN2.
miR-302e Suppresses Glioma Progression by Targeting VEGFA.
Exosomes derived from 5-fluorouracil-resistant colon cancer cells are enriched in GDF15 and can promote angiogenesis.
NFE2L3 promotes malignant behavior and EMT of human hepatocellular carcinoma (HepG2) cells via Wnt/β‑catenin pathway.
Ligand-independent EphB1 signaling mediates TGF-β-activated CDH2 and promotes lung cancer cell invasion and migration.
Analysis of Differentially Expressed Genes in a Chinese Cohort of Esophageal Squamous Cell Carcinoma.
Caffeic Acid Phenethyl Ester Ameliorates Calcification by Inhibiting Activation of the AKT/NF-κB/NLRP3 Inflammasome Pathway in Human Aortic Valve Interstitial Cells.
UVA Induced Oxidative Stress Was Inhibited by Paeoniflorin/Nrf2 Signaling or PLIN2.
Gelatinases Cleave Dentin Sialoprotein Intracellularly.
Salvianolic Acid A Has Anti-Osteoarthritis Effect In Vitro and In Vivo.
Notch3 Modulates Cardiac Fibroblast Proliferation, Apoptosis, and Fibroblast to Myofibroblast Transition via Negative Regulation of the RhoA/ROCK/Hif1α Axis.
Obg-Like ATPase 1 Enhances Chemoresistance of Breast Cancer via Activation of TGF-β/Smad Axis Cascades.
Ursolic Acid Regulates Cell Cycle and Proliferation in Colon Adenocarcinoma by Suppressing Cyclin B1.
Pristimerin Suppresses RANKL-Induced Osteoclastogenesis and Ameliorates Ovariectomy-Induced Bone Loss.
Integrating Network Pharmacology and Experimental Validation to Investigate the Effects and Mechanism of Astragalus Flavonoids Against Hepatic Fibrosis.
Butylphthalide Inhibits Autophagy and Promotes Multiterritory Perforator Flap Survival.
Role of GABRD Gene Methylation in the Nucleus Accumbens in Heroin-Seeking Behavior in Rats.
Elucidation of the Mechanism of Action of Ginseng Against Acute Lung Injury/Acute Respiratory Distress Syndrome by a Network Pharmacology-Based Strategy.
Isorhamnetin Enhances the Radiosensitivity of A549 Cells Through Interleukin-13 and the NF-κB Signaling Pathway.
A Rare KIF1A Missense Mutation Enhances Synaptic Function and Increases Seizure Activity.
Oleoylethanolamide Protects Against Acute Liver Injury by Regulating Nrf-2/HO-1 and NLRP3 Pathways in Mice.
Stimulation of Vibratory Urticaria-Associated Adhesion-GPCR, EMR2/ADGRE2, Triggers the NLRP3 Inflammasome Activation Signal in Human Monocytes.
Isoquercitrin Ameliorates Cisplatin-Induced Nephrotoxicity Via the Inhibition of Apoptosis, Inflammation, and Oxidative Stress.
Poly(dA:dT) Suppresses HSV-2 Infection of Human Cervical Epithelial Cells Through RIG-I Activation.
A Longitudinal Study of T2 Mapping Combined With Diffusion Tensor Imaging to Quantitatively Evaluate Tissue Repair of Rat Skeletal Muscle After Frostbite.
Human Umbilical Cord Mesenchymal Stem Cell Differentiation Into Odontoblast-Like Cells and Endothelial Cells: A Potential Cell Source for Dental Pulp Tissue Engineering.
Tanshinone IIA Inhibits Epithelial-to-Mesenchymal Transition Through Hindering β-Arrestin1 Mediated β-Catenin Signaling Pathway in Colorectal Cancer.
MiR-497-5p Regulates Osteo/Odontogenic Differentiation of Stem Cells From Apical Papilla via the Smad Signaling Pathway by Targeting Smurf2.
A Novel Transcript Isoform of TBK1 Negatively Regulates Type I IFN Production by Promoting Proteasomal Degradation of TBK1 and Lysosomal Degradation of IRF3.
Seneca Valley Virus 3C Protease Inhibits Stress Granule Formation by Disrupting eIF4GI-G3BP1 Interaction.
Evodiamine Attenuates Experimental Colitis Injury Via Activating Autophagy and Inhibiting NLRP3 Inflammasome Assembly.
Chidamide Inhibits Acute Myeloid Leukemia Cell Proliferation by lncRNA VPS9D1-AS1 Downregulation via MEK/ERK Signaling Pathway.
Transcriptomic Analysis of Glycolysis-Related Genes Reveals an Independent Signature of Bladder Carcinoma.
Sleep Deprivation Induces Cognitive Impairment by Increasing Blood-Brain Barrier Permeability via CD44.
Protective effects of taurine against muscle damage induced by diquat in 35 days weaned piglets.
The Endogenous Alterations of the Gut Microbiota and Feces Metabolites Alleviate Oxidative Damage in the Brain of LanCL1 Knockout Mice.
Protective Effects and Possible Mechanisms of Actions of Bushen Cuyun Recipe on Diminished Ovarian Reserve Induced by Cyclophosphamide in Rats.
Mechanical Stretch Induces Smooth Muscle Cell Dysfunction by Regulating ACE2 via P38/ATF3 and Post-transcriptional Regulation by miR-421.
Hepatitis B Core Antigen Impairs the Polarization While Promoting the Production of Inflammatory Cytokines of M2 Macrophages via the TLR2 Pathway.
Investigation of the Lipid-Lowering Mechanisms and Active Ingredients of Danhe Granule on Hyperlipidemia Based on Systems Pharmacology.
Lian Hua Qing Wen Capsules, a Potent Epithelial Protector in Acute Lung Injury Model, Block Proapoptotic Communication Between Macrophages, and Alveolar Epithelial Cells.
Differential Expression and Alternative Splicing of Transcripts Associated With Cisplatin-Induced Chemoresistance in Nasopharyngeal Carcinoma.
Fibroblast Growth Factor 1 Ameliorates Diabetes-Induced Liver Injury by Reducing Cellular Stress and Restoring Autophagy.
C-X-C Motif Chemokine 10 Contributes to the Development of Neuropathic Pain by Increasing the Permeability of the Blood-Spinal Cord Barrier.
Antimicrobial Role of RNASET2 Protein During Innate Immune Response in the Medicinal Leech Hirudo verbana.
Single-Anastomosis Duodenal Jejunal Bypass Improve Glucose Metabolism by Regulating Gut Microbiota and Short-Chain Fatty Acids in Goto-Kakisaki Rats.
Reduced Let-7f in Bone Marrow-Derived Mesenchymal Stem Cells Triggers Treg/Th17 Imbalance in Patients With Systemic Lupus Erythematosus.
Tilianin Extracted From Dracocephalum moldavica L. Induces Intrinsic Apoptosis and Drives Inflammatory Microenvironment Response on Pharyngeal Squamous Carcinoma Cells via Regulating TLR4 Signaling Pathways.
HPV16 E6/E7 promote the translocation and glucose uptake of GLUT1 by PI3K/AKT pathway via relieving miR-451 inhibitory effect on CAB39 in lung cancer cells.
Scutellarein inhibits BLM-mediated pulmonary fibrosis by affecting fibroblast differentiation, proliferation, and apoptosis.
Critical Role of AdipoR1 in Regulating Th17 Cell Differentiation Through Modulation of HIF-1α-Dependent Glycolysis.
Treatment and Prevention of Lung Cancer Using a Virus-Infected Reprogrammed Somatic Cell-Derived Tumor Cell Vaccination (VIReST) Regime.
MiR-362-5p, Which Is Regulated by Long Non-Coding RNA MBNL1-AS1, Promotes the Cell Proliferation and Tumor Growth of Bladder Cancer by Targeting QKI.
Csf2 Attenuated Sepsis-Induced Acute Kidney Injury by Promoting Alternative Macrophage Transition.
Combined Proteome and Transcriptome Analysis of Heat-Primed Azalea Reveals New Insights Into Plant Heat Acclimation Memory.
Maimendong Decoction Improves Pulmonary Function in Rats With Idiopathic Pulmonary Fibrosis by Inhibiting Endoplasmic Reticulum Stress in AECIIs.
The Protective Effect of Luteolin in Glucocorticoid-Induced Osteonecrosis of the Femoral Head.
Gallic Acid Attenuates Angiotensin II-Induced Hypertension and Vascular Dysfunction by Inhibiting the Degradation of Endothelial Nitric Oxide Synthase.
Metformin Mitigates Cartilage Degradation by Activating AMPK/SIRT1-Mediated Autophagy in a Mouse Osteoarthritis Model.
AKT Inhibitor SC66 Inhibits Proliferation and Induces Apoptosis in Human Glioblastoma Through Down-Regulating AKT/β-Catenin Pathway.
De novo Synthesis of SAA1 in the Placenta Participates in Parturition.
MiR-185-5p Protects Against Angiogenesis in Polycystic Ovary Syndrome by Targeting VEGFA.
Inhibition of JNK-Mediated Autophagy Promotes Proscillaridin A- Induced Apoptosis via ROS Generation, Intracellular Ca+2 Oscillation and Inhibiting STAT3 Signaling in Breast Cancer Cells.
PAQR4 promotes chemoresistance in non-small cell lung cancer through inhibiting Nrf2 protein degradation.
CNTNAP4 deficiency in dopaminergic neurons initiates parkinsonian phenotypes.
SMYD2 suppresses APC2 expression to activate the Wnt/β-catenin pathway and promotes epithelial-mesenchymal transition in colorectal cancer.
Fasudil Promotes α-Synuclein Clearance in an AAV-Mediated α-Synuclein Rat Model of Parkinson's Disease by Autophagy Activation.
Denervation drives skeletal muscle atrophy and induces mitochondrial dysfunction, mitophagy and apoptosis via miR-142a-5p/MFN1 axis.
Promotion of mitochondrial fusion protects against developmental PBDE-47 neurotoxicity by restoring mitochondrial homeostasis and suppressing excessive apoptosis.
Virus-induced p38 MAPK activation facilitates viral infection.
Restoring the epigenetically silenced PCK2 suppresses renal cell carcinoma progression and increases sensitivity to sunitinib by promoting endoplasmic reticulum stress.
TSTA3 facilitates esophageal squamous cell carcinoma progression through regulating fucosylation of LAMP2 and ERBB2.
Truncated HDAC9 identified by integrated genome-wide screen as the key modulator for paclitaxel resistance in triple-negative breast cancer.
Hypergastrinemia Expands Gastric ECL Cells Through CCK2R+ Progenitor Cells via ERK Activation.
LncRNA CSMD1-1 promotes the progression of Hepatocellular Carcinoma by activating MYC signaling.
Protein acetylation derepresses Serotonin Synthesis to potentiate Pancreatic Beta-Cell Function through HDAC1-PKA-Tph1 signaling.
Diethyldithiocarbamate-copper nanocomplex reinforces disulfiram chemotherapeutic efficacy through light-triggered nuclear targeting.
Selective targeting of the oncogenic KRAS G12S mutant allele by CRISPR/Cas9 induces efficient tumor regression.
Circ-EEF2 facilitated autophagy via interaction with mir-6881-3p and ANXA2 in EOC.
LncRNA NEAT1 facilitates pancreatic cancer growth and metastasis through stabilizing ELF3 mRNA.
Ovary Proteome Analysis Reveals RH36 Regulates Reproduction via Vitellin Uptake Mediated by HSP70 Protein in Hard Ticks.
KLF13 suppresses the proliferation and growth of colorectal cancer cells through transcriptionally inhibiting HMGCS1-mediated cholesterol biosynthesis.
RAC1 Involves in the Radioresistance by Mediating Epithelial-Mesenchymal Transition in Lung Cancer.
Long Noncoding RNA UCA1 Is Related to Autophagy and Apoptosis in Endometrial Stromal Cells.
circ_NOTCH3 Functions as a Protooncogene Competing With miR-205-5p, Modulating KLF12 Expression and Promoting the Development and Progression of Basal-Like Breast Carcinoma.
MLK3 Is Associated With Poor Prognosis in Patients With Glioblastomas and Actin Cytoskeleton Remodeling in Glioblastoma Cells.
Antioxidant Effect of Propofol in Gliomas and Its Association With Divalent Metal Transporter 1.
Characterization of ROS Metabolic Equilibrium Reclassifies Pan-Cancer Samples and Guides Pathway Targeting Therapy.
Long Non-Coding RNA LINC02747 Promotes the Proliferation of Clear Cell Renal Cell Carcinoma by Inhibiting miR-608 and Activating TFE3.
PUF60/AURKA Axis Contributes to Tumor Progression and Malignant Phenotypes in Bladder Cancer.
Vitamin D3 Inhibits Helicobacter pylori Infection by Activating the VitD3/VDR-CAMP Pathway in Mice.
Single-Cell Sequencing of Glioblastoma Reveals Central Nervous System Susceptibility to SARS-CoV-2.
BYSL Promotes Glioblastoma Cell Migration, Invasion, and Mesenchymal Transition Through the GSK-3β/β-Catenin Signaling Pathway.
TDO2 Promotes the EMT of Hepatocellular Carcinoma Through Kyn-AhR Pathway.
Carbohydrate Sulfotransferase 4 Inhibits the Progression of Hepatitis B Virus-Related Hepatocellular Carcinoma and Is a Potential Prognostic Marker in Several Tumors.
FOXK1 Promotes Proliferation and Metastasis of Gallbladder Cancer by Activating AKT/mTOR Signaling Pathway.
Thioguanine Induces Apoptosis in Triple-Negative Breast Cancer by Regulating PI3K-AKT Pathway.
Long Non-coding RNA CCAT1 Acts as an Oncogene and Promotes Sunitinib Resistance in Renal Cell Carcinoma.
CDC27 Promotes Tumor Progression and Affects PD-L1 Expression in T-Cell Lymphoblastic Lymphoma.
Nicotine Reduces Human Brain Microvascular Endothelial Cell Response to Escherichia coli K1 Infection by Inhibiting Autophagy.
Nevirapine Increases Sodium/Iodide Symporter-Mediated Radioiodide Uptake by Activation of TSHR/cAMP/CREB/PAX8 Signaling Pathway in Dedifferentiated Thyroid Cancer.
EGFR/FOXO3A/LXR-α Axis Promotes Prostate Cancer Proliferation and Metastasis and Dual-Targeting LXR-α/EGFR Shows Synthetic Lethality.
miR-15b-5p Promotes Growth and Metastasis in Breast Cancer by Targeting HPSE2.
Conditional ablation of MAPK7 expression in chondrocytes impairs endochondral bone formation in limbs and adaptation of chondrocytes to hypoxia.
The neuro-immune interaction in airway inflammation through TRPA1 expression in CD4+ T cells of asthmatic mice.
Curcumin ameliorates CKD-induced mitochondrial dysfunction and oxidative stress through inhibiting GSK-3β activity.
Resveratrol inhibits the tumor migration and invasion by upregulating TET1 and reducing TIMP2/3 methylation in prostate carcinoma cells.
METTL7B (methyltransferase-like 7B) identification as a novel biomarker for lung adenocarcinoma.
Magnolol inhibits myotube atrophy induced by cancer cachexia through myostatin signaling pathway in vitro.
Bisphenol-A exposure induced neurotoxicity and associated with synapse and cytoskeleton in Neuro-2a cells.
Islet-cell autoantigen 69 accelerates liver regeneration by downregulating Tgfbr1 and attenuating Tgfβ signaling in mice.
GBP1 promotes erlotinib resistance via PGK1‑activated EMT signaling in non‑small cell lung cancer.
ID1 overexpression promotes HCC progression by amplifying the AURKA/Myc signaling pathway.
Protein phosphorylation profiling of peripheral nerve regeneration after autologous nerve grafting.
High glucose condition inhibits trophoblast proliferation, migration and invasion by downregulating placental growth factor expression.
Sodium Butyrate Exacerbates Parkinson's Disease by Aggravating Neuroinflammation and Colonic Inflammation in MPTP-Induced Mice Model.
A Novel Compound YS-5-23 Exhibits Neuroprotective Effect by Reducing β-Site Amyloid Precursor Protein Cleaving Enzyme 1's Expression and H2O2-Induced Cytotoxicity in SH-SY5Y Cells.
ErbB4 knockdown in serotonergic neurons in the dorsal raphe induces anxiety-like behaviors.
Differential regulation of Actn2 and Actn3 expression during unfolded protein response in C2C12 myotubes.
Mitochondrial superoxide contributes to oxidative stress exacerbated by DNA damage response in RAD51-depleted ovarian cancer cells.
Obesity promotes gastric cancer metastasis via diacylglycerol acyltransferase 2-dependent lipid droplets accumulation and redox homeostasis.
Vagus Nerve Stimulation Attenuates Early Traumatic Brain Injury by Regulating the NF-κB/NLRP3 Signaling Pathway.
APC2CDH1 negatively regulates agrin signaling by promoting the ubiquitination and proteolytic degradation of DOK7.
Selenoprotein T protects against cisplatin-induced acute kidney injury through suppression of oxidative stress and apoptosis.
The MAF1 Phosphoregulatory Region Controls MAF1 Interaction with the RNA Polymerase III C34 Subunit and Transcriptional Repression in Plants.
A paralog-specific role of COPI vesicles in the neuronal differentiation of mouse pluripotent cells.
The deubiquitylase USP2 maintains ErbB2 abundance via counteracting endocytic degradation and represents a therapeutic target in ErbB2-positive breast cancer.
Cardioprotection by isosteviol derivate JC105: A unique drug property to activate ERK1/2 only when cells are exposed to hypoxia-reoxygenation.
Decreased ANGPTL4 impairs endometrial angiogenesis during peri-implantation period in patients with recurrent implantation failure.
Follicle-stimulating hormone impairs dental pulp stem cells odontogenic differentiation.
Musashi2 promotes the progression of pancreatic cancer through a novel ISYNA1-p21/ZEB-1 pathway.
AKR1C2 acts as a targetable oncogene in esophageal squamous cell carcinoma via activating PI3K/AKT signaling pathway.
Aberrant ASPM expression mediated by transcriptional regulation of FoxM1 promotes the progression of gliomas.
UVA influenced the SIRT1-miR-27a-5p-SMAD2-MMP1/COL1/BCL2 axis in human skin primary fibroblasts.
Deubiquitinase USP13 promotes extracellular matrix expression by stabilizing Smad4 in lung fibroblast cells.
TRIM11 promotes breast cancer cell proliferation by stabilizing estrogen receptor α.
Circular RNA hsa_circ_0005556 Accelerates Gastric Cancer Progression by Sponging miR-4270 to Increase MMP19 Expression.
Antiviral immune mechanism of Toll-like receptor 4-mediated human alveolar epithelial cells type Ⅱ.
Oxidation of multiple MiT/TFE transcription factors links oxidative stress to transcriptional control of autophagy and lysosome biogenesis.
Myeloid Cell Expression of LACC1 Is Required for Bacterial Clearance and Control of Intestinal Inflammation.
BAIAP2L2 promotes the progression of gastric cancer via AKT/mTOR and Wnt3a/β-catenin signaling pathways.
PM2.5 compromises antiviral immunity in influenza infection by inhibiting activation of NLRP3 inflammasome and expression of interferon-β.
Novel long non-coding RNA LINC02323 promotes epithelial-mesenchymal transition and metastasis via sponging miR-1343-3p in lung adenocarcinoma.
Icariside Ⅱ, a main compound in Epimedii Folium, induces idiosyncratic hepatotoxicity by enhancing NLRP3 inflammasome activation.
Impaired NHEJ repair in amyotrophic lateral sclerosis is associated with TDP-43 mutations.
Functional regulation of an ancestral RAG transposon ProtoRAG by a trans-acting factor YY1 in lancelet.
Legionella Manipulates Non-canonical SNARE Pairing Using a Bacterial Deubiquitinase.
MiR-126 Regulates Properties of SOX9+ Liver Progenitor Cells during Liver Repair by Targeting Hoxb6.
Knockdown of TXNDC9 induces apoptosis and autophagy in glioma and mediates cell differentiation by p53 activation.
Autocrine INSL5 promotes tumor progression and glycolysis via activation of STAT5 signaling.
hUMSCs regulate the differentiation of ovarian stromal cells via TGF-β1/Smad3 signaling pathway to inhibit ovarian fibrosis to repair ovarian function in POI rats.
Palmatine ameliorates Helicobacter pylori-induced chronic atrophic gastritis by inhibiting MMP-10 through ADAM17/EGFR.
Long non-coding RNA FAM133B-2 represses the radio-resistance of nasopharyngeal cancer cells by targeting miR-34a-5p/CDK6 axis.
Neuroprotective Effect of Piracetam against Cocaine-Induced Neuro Epigenetic Modification of DNA Methylation in Astrocytes.
Aristolochic acid I promotes the invasion and migration of hepatocellular carcinoma cells by activating the C3a/C3aR complement system.
YAP1 Inhibition in HUVECs Is Associated with Released Exosomes and Increased Hepatocarcinoma Invasion and Metastasis.
Circular RNA circREPS2 Acts as a Sponge of miR-558 to Suppress Gastric Cancer Progression by Regulating RUNX3/β-catenin Signaling.
Fc-Elabela fusion protein attenuates lipopolysaccharide-induced kidney injury in mice.
Porphyromonas gingivalis disrupts vascular endothelial homeostasis in a TLR-NF-κB axis dependent manner.
Anti-bacterial and anti-viral nanchangmycin displays anti-myeloma activity by targeting Otub1 and c-Maf.
Quality Control of ER Membrane Proteins by the RNF185/Membralin Ubiquitin Ligase Complex.
Aldehyde dehydrogenase 2 inhibited oxidized LDL-induced NLRP3 inflammasome priming and activation via attenuating oxidative stress.
KLF16 overexpression deleteriously affects the proliferation and migration of retinoblastoma by transcriptionally repressing BCL2L15.
BAP1 regulates AMPK-mTOR signalling pathway through deubiquitinating and stabilizing tumour-suppressor LKB1.
The microRNA/TET3/REST axis is required for olfactory globose basal cell proliferation and male behavior.
TRIM29 inhibits miR-873-5P biogenesis via CYTOR to upregulate fibronectin 1 and promotes invasion of papillary thyroid cancer cells.
Maternal sevoflurane exposure affects differentiation of hippocampal neural stem cells by regulating miR-410-3p and ATN1.
Antimicrobial Effect of Zophobas morio Hemolymph against Bovine Mastitis Pathogens.
Small-molecule MMP2/MMP9 inhibitor SB-3CT modulates tumor immune surveillance by regulating PD-L1.
Establishment and characterization of a PCOS and a normal human granulosa cell line.
Multi-Compartment, Early Disruption of cGMP and cAMP Signalling in Cardiac Myocytes from the mdx Model of Duchenne Muscular Dystrophy.
Imaging-Based Reporter Systems to Define CVB-Induced Membrane Remodeling in Living Cells.
RNA-binding protein CUGBP1 controls the differential INSR splicing in molecular subtypes of breast cancer cells and affects cell aggressiveness.
MSC-derived exosomes promote recovery from traumatic brain injury via microglia/macrophages in rat.
Peptidome analysis of umbilical cord mesenchymal stem cell (hUC-MSC) conditioned medium from preterm and term infants.
Bardoxolone conjugation enables targeted protein degradation of BRD4.
CD36 facilitates fatty acid uptake by dynamic palmitoylation-regulated endocytosis.
miR-29a Modulates GSK3β/SIRT1-Linked Mitochondrial Proteostatic Stress to Ameliorate Mouse Non-Alcoholic Steatohepatitis.
NRF2 preserves genomic integrity by facilitating ATR activation and G2 cell cycle arrest.
Complex I mutations synergize to worsen the phenotypic expression of Leber's hereditary optic neuropathy.
Zinc oxide nanoparticles effectively regulate autophagic cell death by activating autophagosome formation and interfering with their maturation.
Cepharanthine and Curcumin inhibited mitochondrial apoptosis induced by PCV2.
Resveratrol alleviates the interleukin-1β-induced chondrocytes injury through the NF-κB signaling pathway.
AKT2 regulates development and metabolic homeostasis via AMPK-depedent pathway in skeletal muscle.
Cyclin G2 Is Involved in the Proliferation of Placental Trophoblast Cells and Their Interactions with Endothelial Cells.
Stachydrine hydrochloride suppresses phenylephrine-induced pathological cardiac hypertrophy by inhibiting the calcineurin/nuclear factor of activated T-cell signalling pathway.
α-Cyperone inhibits the proliferation of human cervical cancer HeLa cells via ROS-mediated PI3K/Akt/mTOR signaling pathway.
MicroRNA-183 exerts a protective role in lupus nephritis through blunting the activation of TGF-β/Smad/TLR3 pathway via reducing Tgfbr1.
The Natural Compound Notopterol Binds and Targets JAK2/3 to Ameliorate Inflammation and Arthritis.
A tRNA-derived fragment (tRF-3001b) aggravates the development of nonalcoholic fatty liver disease by inhibiting autophagy.
Inhibition of PP2A enhances the osteogenic differentiation of human aortic valvular interstitial cells via ERK and p38 MAPK pathways.
Paired box 9 regulates VSMC phenotypic transformation, proliferation, and migration via sonic hedgehog.
Melatonin rescues glucocorticoid-induced inhibition of osteoblast differentiation in MC3T3-E1 cells via the PI3K/AKT and BMP/Smad signalling pathways.
BMSC-derived exosomes alleviate smoke inhalation lung injury through blockade of the HMGB1/NF-κB pathway.
High fat diet impairs spermatogenesis by regulating glucose and lipid metabolism in Sertoli cells.
Sphingomyelin Synthase 2 Participate in the Regulation of Sperm Motility and Apoptosis.
Overactivated sonic hedgehog signaling aggravates intrauterine adhesion via inhibiting autophagy in endometrial stromal cells.
Troxerutin protects against DHT-induced polycystic ovary syndrome in rats.
Tectorigenin enhances PDX1 expression and protects pancreatic β-cells by activating ERK and reducing ER stress.
The protoapigenone analog WYC0209 targets CD133+ cells: A potential adjuvant agent against cancer stem cells in urothelial cancer therapy.
The vicious cycle between ferritinophagy and ROS production triggered EMT inhibition of gastric cancer cells was through p53/AKT/mTor pathway.
Tp53 Suppression Promotes Cardiomyocyte Proliferation during Zebrafish Heart Regeneration.
Downregulation of PIF1, a potential new target of MYCN, induces apoptosis and inhibits cell migration in neuroblastoma cells.
Four active monomers from Moutan Cortex exert inhibitory effects against oxidative stress by activating Nrf2/Keap1 signaling pathway.
FERMT1 promotes gastric cancer progression by activating the NF-κB pathway and predicts poor prognosis.
A novel antiviral lncRNA, EDAL, shields a T309 O-GlcNAcylation site to promote EZH2 lysosomal degradation.
Expression Level of Small Envelope Protein in Addition to Sequence Divergence inside Its Major Hydrophilic Region Contributes to More Efficient Surface Antigen Secretion by Hepatitis B Virus Subgenotype D2 than Subgenotype A2.
Dual targeting of NUAK1 and ULK1 using the multitargeted inhibitor MRT68921 exerts potent antitumor activities.
miR-142-5p and miR-130a-3p regulate pulmonary macrophage polarization and asthma airway remodeling.
MiR-375-3p alleviates the severity of inflammation through targeting YAP1/LEKTI pathway in HaCaT cells.
Genome-wide pathogenesis interpretation using a heat diffusion-based systems genetics method and implications for gene function annotation.
Amyotrophic lateral sclerosis-linked UBQLN2 mutants inhibit endoplasmic reticulum to Golgi transport, leading to Golgi fragmentation and ER stress.
Uncovering the mechanism of Astragali Radix against nephrotic syndrome by intergrating lipidomics and network pharmacology.
Senolytic Agent Navitoclax Inhibits Angiotensin II-Induced Heart Failure in Mice.
miR-29b-3p protects cardiomyocytes against endotoxin-induced apoptosis and inflammatory response through targeting FOXO3A.
MYCT1 inhibits the EMT and migration of laryngeal cancer cells via the SP1/miR-629-3p/ESRP2 pathway.
Blocking NFATc3 ameliorates azoxymethane/dextran sulfate sodium induced colitis-associated colorectal cancer in mice via the inhibition of inflammatory responses and epithelial-mesenchymal transition.
Identification of mecciRNAs and their roles in the mitochondrial entry of proteins.
The support of genetic evidence for cardiovascular risk induced by antineoplastic drugs.
Upregulation of secreted phosphoprotein 1 affects malignant progression, prognosis, and resistance to cetuximab via the KRAS/MEK pathway in head and neck cancer.
MiR-34a suppresses the proliferation and invasion of gastric cancer by modulating PDL1 in the immune microenvironment.
Bovine Milk Exosomes Affect Proliferation and Protect Macrophages against Cisplatin-Induced Cytotoxicity.
Generation of homozygous CRISPRa human induced pluripotent stem cell (hiPSC) lines for sustained endogenous gene activation.
sATP‑binding cassette subfamily G member 2 enhances the multidrug resistance properties of human nasal natural killer/T cell lymphoma side population cells.
NLRC3 silencing accelerates the invasion of hepatocellular carcinoma cell via IL-6/JAK2/STAT3 pathway activation.
Internalization of the TAT-PBX1 fusion protein significantly enhances the proliferation of human hair follicle-derived mesenchymal stem cells and delays their senescence.
Pellino1 Contributes to Morphine Tolerance by Microglia Activation via MAPK Signaling in the Spinal Cord of Mice.
Tissue Inhibitor of Metalloprotease-1 (TIMP-1) Regulates Adipogenesis of Adipose-derived Stem Cells (ASCs) via the Wnt Signaling Pathway in an MMP-independent Manner.
3-Methyladenine Alleviates Experimental Subretinal Fibrosis by Inhibiting Macrophages and M2 Polarization Through the PI3K/Akt Pathway.
The role of Caspase-1/GSDMD-mediated pyroptosis in Taxol-induced cell death and a Taxol-resistant phenotype in nasopharyngeal carcinoma regulated by autophagy.
Zbtb20 deficiency causes cardiac contractile dysfunction in mice.
Endothelial microparticles induced by cyclic stretch activate Src and modulate cell apoptosis.
Xanthatin alleviates airway inflammation in asthmatic mice by regulating the STAT3/NF-κB signaling pathway.
Curcumin suppresses the proliferation and tumorigenicity of Cal27 by modulating cancer-associated fibroblasts of TSCC.
Aloe extract inhibits porcine epidemic diarrhea virus in vitro and in vivo.
Emodin inhibiting neutrophil elastase-induced epithelial-mesenchymal transition through Notch1 signalling in alveolar epithelial cells.
Ulinastatin reduces myocardial injury induced by doxorubicin in SD rats.
Selective blocking of CXCR2 prevents and reverses atrial fibrillation in spontaneously hypertensive rats.
Circular RNA circTET3 mediates migration of rat vascular smooth muscle cells by targeting miR-351-5p.
Resveratrol inhibits hypertrophic scars formation by activating autophagy via the miR-4654/Rheb axis.
PRDX2 plays an oncogenic role in esophageal squamous cell carcinoma via Wnt/β-catenin and AKT pathways.
Autophagy-Sirt3 axis decelerates hematopoietic aging.
Over-activation of NMDA receptors promotes ABCA1 degradation and foam cell formation.
ML-SA1, a selective TRPML agonist, inhibits DENV2 and ZIKV by promoting lysosomal acidification and protease activity.
Perillaldehyde: A promising antifungal agent to treat oropharyngeal candidiasis.
TGF-β1-induced miR-424 promotes pulmonary myofibroblast differentiation by targeting Slit2 protein expression.
Inhibition of RUNX1 promotes cisplatin-induced apoptosis in ovarian cancer cells.
Peli1 impairs microglial Aβ phagocytosis through promoting C/EBPβ degradation.
The Long Noncoding RNA NEAT1 Promotes Sarcoma Metastasis by Regulating RNA Splicing Pathways.
Antidiabetic activity in vitro and in vivo of BDB, a selective inhibitor of protein tyrosine phosphatase 1B, from Rhodomela confervoides.
The human ribosomal protein eL29 binds in vivo to the cognate mRNA by interacting with its coding sequence, as revealed from in-cell cross-linking data.
RAGE Signaling pathway in hippocampus dentate gyrus involved in GLT-1 decrease induced by chronic unpredictable stress in rats.
Melatonin improves hypoxic-ischemic brain damage through the Akt/Nrf2/Gpx4 signaling pathway.
RNA demethylase Alkbh5 is widely expressed in neurons and decreased during brain development.
Inhibition of cell migration and induction of apoptosis by a novel class II histone deacetylase inhibitor, MCC2344.
Enhancing PPARγ by HDAC inhibition reduces foam cell formation and atherosclerosis in ApoE deficient mice.
p53 promotes ZDHHC1-mediated IFITM3 palmitoylation to inhibit Japanese encephalitis virus replication.
STYK1 promotes autophagy through enhancing the assembly of autophagy-specific class III phosphatidylinositol 3-kinase complex I.
Identification of osalmid metabolic profile and active metabolites with anti-tumor activity in human hepatocellular carcinoma cells.
Therapeutic effect of phycocyanin on acute liver oxidative damage caused by X-ray.
miR-483-3p promotes cell proliferation and suppresses apoptosis in rheumatoid arthritis fibroblast-like synoviocytes by targeting IGF-1.
Paired like homeodomain 1 and SAM and SH3 domain-containing 1 in the progression and prognosis of head and neck squamous cell carcinoma.
Lnc-MUC20-9 binds to ROCK1 and functions as a tumor suppressor in bladder cancer.
Matrix metalloprotease-mediated cleavage of neural glial-related cell adhesion molecules activates quiescent olfactory stem cells via EGFR.
Renal asymmetric dimethylarginine inhibits fibrosis.
Enhancing site-specific DNA integration by a Cas9 nuclease fused with a DNA donor-binding domain.
Mir-20a-5p induced WTX deficiency promotes gastric cancer progressions through regulating PI3K/AKT signaling pathway.
Calreticulin promotes EMT in pancreatic cancer via mediating Ca2+ dependent acute and chronic endoplasmic reticulum stress.
miR-431-5p regulates cell proliferation and apoptosis in fibroblast-like synoviocytes in rheumatoid arthritis by targeting XIAP.
Effect of Zhenxin Xingshui Yizhi Fang on Aβ25-35 induced expression of related transporters in HBMEC cell model.
Loss of TMEM106B and PGRN leads to severe lysosomal abnormalities and neurodegeneration in mice.
Temporal activation of LRH-1 and RAR-γ in human pluripotent stem cells induces a functional naïve-like state.
Blockade of Glial Connexin 43 Hemichannels Reduces Food Intake.
Defect of SLC38A3 promotes epithelial-mesenchymal transition and predicts poor prognosis in esophageal squamous cell carcinoma.
IGF2BP1 silencing inhibits proliferation and induces apoptosis of high glucose-induced non-small cell lung cancer cells by regulating Netrin-1.
Cancer-associated fibroblasts-derived exosomal miR-17-5p promotes colorectal cancer aggressive phenotype by initiating a RUNX3/MYC/TGF-β1 positive feedback loop.
HIF-1α-Mediated Mitophagy Determines ZnO Nanoparticle-Induced Human Osteosarcoma Cell Death both In Vitro and In Vivo.
Circular RNA circ_PVT1 induces epithelial-mesenchymal transition to promote metastasis of cervical cancer.
Nicotine Causes Nephrotoxicity through the Induction of NLRP6 Inflammasome and Alpha7 Nicotinic Acetylcholine Receptor.
A Dedicated Evolutionarily Conserved Molecular Network Licenses Differentiated Cells to Return to the Cell Cycle.
CACNA1B facilitates breast cancer cell growth and migration by regulating cyclin D1 and EMT: the implication of CACNA1B in breast cancer.
Myostatin regulates fatty acid desaturation and fat deposition through MEF2C/miR222/SCD5 cascade in pigs.
Inhibition of ROS/NLRP3/Caspase-1 mediated pyroptosis attenuates cadmium-induced apoptosis in duck renal tubular epithelial cells.
PD-1 Regulates GABAergic Neurotransmission and GABA-Mediated Analgesia and Anesthesia.
USP52 regulates DNA end resection and chemosensitivity through removing inhibitory ubiquitination from CtIP.
Functional validation of a human GLUD2 variant in a murine model of Parkinson's disease.
Phosphodiesterase 2A2 regulates mitochondria clearance through Parkin-dependent mitophagy.
Loss of PRCD alters number and packaging density of rhodopsin in rod photoreceptor disc membranes.
Emergence of Carbapenem-Resistant Providencia rettgeri and Providencia stuartii Producing IMP-Type Metallo-β-Lactamase in Japan.
A Regulation Loop between YAP and NR4A1 Balances Cell Proliferation and Apoptosis.
Novel Therapeutic Insights in Dedifferentiated Liposarcoma: A Role for FGFR and MDM2 Dual Targeting.
Targeting interleukin-17 receptor B enhances gemcitabine sensitivity through downregulation of mucins in pancreatic cancer.
Expression of STAT1 is positively correlated with PD-L1 in human ovarian cancer.
Multiple-Purpose Connectivity Map Analysis Reveals the Benefits of Esculetin to Hyperuricemia and Renal Fibrosis.
Antioxidant Apigenin Relieves Age-Related Muscle Atrophy by Inhibiting Oxidative Stress and Hyperactive Mitophagy and Apoptosis in Skeletal Muscle of Mice.
Autophagy regulates exosome secretion in rat nucleus pulposus cells via the RhoC/ROCK2 pathway.
SARS-CoV-2 targets neurons of 3D human brain organoids.
XK is a partner for VPS13A: a molecular link between Chorea-Acanthocytosis and McLeod Syndrome.
Ambient fine particulate matter induced the elevation of blood pressure through ACE2/Ang(1-7) pathway: The evidence from urine metabolites.
A novel pectin from Polygala tenuifolia blocks Aβ42 aggregation and production by enhancing insulin-degradation enzyme and neprilysin.
Structures and anti-atherosclerotic effects of 1,6-α-glucans from Fructus Corni.
Melatonin suppresses ER stress-dependent proapoptotic effects via AMPK in bone mesenchymal stem cells during mitochondrial oxidative damage.
BKCa channels regulate the immunomodulatory properties of WJ-MSCs by affecting the exosome protein profiles during the inflammatory response.
Identification of Fibroblast Activation Protein as an Osteogenic Suppressor and Anti-osteoporosis Drug Target.
PERK controls bone homeostasis through the regulation of osteoclast differentiation and function.
TAp63α targeting of Lgr5 mediates colorectal cancer stem cell properties and sulforaphane inhibition.
USP7 mediates pathological hepatic de novo lipogenesis through promoting stabilization and transcription of ZNF638.
Landscape characterization of chimeric RNAs in colorectal cancer.
The RNA exosome complex degrades expanded hexanucleotide repeat RNA in C9orf72 FTLD/ALS.
3-Mercaptopyruvate sulfurtransferase/hydrogen sulfide protects cerebral endothelial cells against oxygen-glucose deprivation/reoxygenation-induced injury via mitoprotection and inhibition of the RhoA/ROCK pathway.
Type 2 diabetes-induced overactivation of P300 contributes to skeletal muscle atrophy by inhibiting autophagic flux.
Role and mechanism of PI3K/AKT/FoxO1/PDX-1 signaling pathway in functional changes of pancreatic islets in rats after severe burns.
Platycodon grandifloras polysaccharides inhibit mitophagy injury induced by Cr (VI) in DF-1 cells.
Targeting Mitochondria-Located circRNA SCAR Alleviates NASH via Reducing mROS Output.
Amifostine ameliorates induction of experimental autoimmune encephalomyelitis: Effect on reactive oxygen species/NLRP3 pathway.
microRNA-421-3p prevents inflammatory response in cerebral ischemia/reperfusion injury through targeting m6A Reader YTHDF1 to inhibit p65 mRNA translation.
Wilms' tumor 1-associating protein contributes to psoriasis by promoting keratinocytes proliferation via regulating cyclinA2 and CDK2.
PDLIM2 protects articular chondrocytes from lipopolysaccharide-induced apoptosis, degeneration and inflammatory injury through down-regulation of nuclear factor (NF)-κB signaling.
Emodin ameliorates ovalbumin-induced airway remodeling in mice by suppressing airway smooth muscle cells proliferation.
The role of WNT1 mutant variant (WNT1c.677C>T ) in osteogenesis imperfecta.
Ginsenoside Rg3 attenuates ovariectomy-induced osteoporosis via AMPK/mTOR signaling pathway.
RSPO3 is a marker candidate for predicting tumor aggressiveness in ovarian cancer.
SOX2 promotes resistance of melanoma with PD-L1 high expression to T-cell-mediated cytotoxicity that can be reversed by SAHA.
The metabolic response to inflammation in astrocytes is regulated by nuclear factor-kappa B signaling.
The molecular basis of tight nuclear tethering and inactivation of cGAS.
Loss of core fucosylation enhances the anticancer activity of cytotoxic T lymphocytes by increasing PD-1 degradation.
N‑linoleyltyrosine protects PC12 cells against oxidative damage via autophagy: Possible involvement of CB1 receptor regulation.
Association of tricellulin expression with poor colorectal cancer prognosis and metastasis.
Caveolin-1 upregulates Fut8 expression by activating the Wnt/β-catenin pathway to enhance HCC cell proliferative and invasive ability.
MG53 protects against contrast-induced acute kidney injury by reducing cell membrane damage and apoptosis.
The role of protein kinase C alpha in tri-ortho-cresyl phosphate-induced autophagy in human neuroblastoma SK-N-SH cells.
Nanog mediates tobacco smoke-induced enhancement of renal cancer stem cell properties.
In vivo immunotoxicity of Gd2 O3 :Eu3+ nanoparticles and the associated molecular mechanism.
SNORA71B promotes breast cancer cells across blood-brain barrier by inducing epithelial-mesenchymal transition.
RBMX is required for activation of ATR on repetitive DNAs to maintain genome stability.
MyoD1 suppresses cell migration and invasion by inhibiting FUT4 transcription in human gastric cancer cells.
TRPV4 promotes acoustic wave-mediated BBB opening via Ca2+/PKC-δ pathway.
Hydroquinone inhibits PRV infection in neurons in vitro and in vivo.
ndufa7 plays a critical role in cardiac hypertrophy.
Down-regulated HDAC3 elevates microRNA-495-3p to restrain epithelial-mesenchymal transition and oncogenicity of melanoma cells via reducing TRAF5.
Long noncoding RNA TCONS-00106987 promotes atrial electrical remodelling during atrial fibrillation by sponging miR-26 to regulate KCNJ2.
Cathepsin L promotes angiogenesis by regulating the CDP/Cux/VEGF-D pathway in human gastric cancer.
Overexpression of G3BP1 facilitates the progression of colon cancer by activating β‑catenin signaling.
miR‑155 modulates high glucose‑induced cardiac fibrosis via the Nrf2/HO‑1 signaling pathway.
The AKT inhibitor MK2206 suppresses airway inflammation and the pro‑remodeling pathway in a TDI‑induced asthma mouse model.
LncRNA GAS5 inhibits NLRP3 inflammasome activation-mediated pyroptosis in diabetic cardiomyopathy by targeting miR-34b-3p/AHR.
Crosstalk between pleural mesothelial cell and lung fibroblast contributes to pulmonary fibrosis.
Paired associated magnetic stimulation promotes neural repair in the rat middle cerebral artery occlusion model of stroke.
TRAF6 Activates Fibroblasts to Cancer-Associated Fibroblasts through FGF19 in Tumor Microenvironment to Benefit the Malignant Phenotype of Melanoma Cells.
Pomegranate flower extract bidirectionally regulates the proliferation, differentiation and apoptosis of 3T3-L1 cells through regulation of PPARγ expression mediated by PI3K-AKT signaling pathway.
Type 2 diabetes mellitus facilitates endometrial hyperplasia progression by activating the proliferative function of mucin O-glycosylating enzyme GALNT2.
Indirubin alleviates bleomycin-induced pulmonary fibrosis in mice by suppressing fibroblast to myofibroblast differentiation.
Exosome secreted by human gingival fibroblasts in radiation therapy inhibits osteogenic differentiation of bone mesenchymal stem cells by transferring miR-23a.
The long noncoding RNA FTX promotes a malignant phenotype in bone marrow mesenchymal stem cells via the miR-186/c-Met axis.
Enhancement of anti-acne effect of Scutellaria baicalensis extract by fermentation with symbiotic fungus Penicillium decumbens.
Nucleoredoxin interaction with flightless-I/actin complex is differentially altered in alcoholic liver disease.
NLRC3-like 1 inhibits NOD1-RIPK2 pathway via targeting RIPK2.
TGF-β2 interfering oligonucleotides used as adjuvants for microbial vaccines.
Overexpression of Dnmt3a ameliorates diabetic muscle atrophy by modulating the Pten/Akt pathway.
Two resveratrol analogs, pinosylvin and 4,4'-dihydroxystilbene, improve oligoasthenospermia in a mouse model by attenuating oxidative stress via the Nrf2-ARE pathway.
MiR-124-3p promotes trophoblast cell HTR-8/SVneo pyroptosis by targeting placental growth factor.
MiR-185-5p ameliorates endoplasmic reticulum stress and renal fibrosis by downregulation of ATF6.
Cholestasis impairs hepatic lipid storage via AMPK and CREB signaling in hepatitis B virus surface protein transgenic mice.
Inositol-Requiring Enzyme 1α Promotes Zika Virus Infection through Regulation of Stearoyl Coenzyme A Desaturase 1-Mediated Lipid Metabolism.
Oroxylin A alleviates immunoparalysis of CLP mice by degrading CHOP through interacting with FBXO15.
Long-wave Ultraviolet Ray Promotes Inflammation in Keloid-derived Fibroblasts by Activating P38-NFκB1 Signaling Pathway.
Macrophage-derived small extracellular vesicles promote biomimetic mineralized collagen-mediated endogenous bone regeneration.
miR-206 as a prognostic and sensitivity biomarker for platinum chemotherapy in epithelial ovarian cancer.
Smyd3-PARP16 axis accelerates unfolded protein response and vascular aging.
Grape Seed Proanthocyanidins Induce Apoptosis and Cell Cycle Arrest of HepG2 Cells Accompanied by Induction of the MAPK Pathway and NAG-1.
IQGAP3 interacts with Rad17 to recruit the Mre11-Rad50-Nbs1 complex and contributes to radioresistance in lung cancer.
Calnexin mediates the maturation of GPI-anchors through ER retention.
Catalysis of proline isomerization and molecular chaperone activity in a tug-of-war.
SAHA Overcomes 5-FU Resistance in IFIT2-Depleted Oral Squamous Cell Carcinoma Cells.
Effect of conditioned medium from neural stem cells on glioma progression and its protein expression profile analysis.
Legumain is a predictor of all-cause mortality and potential therapeutic target in acute myocardial infarction.
Protective Effects of Fucoxanthin on High Glucose- and 4-Hydroxynonenal (4-HNE)-Induced Injury in Human Retinal Pigment Epithelial Cells.
The effect of whey protein on viral infection and replication of SARS-CoV-2 and pangolin coronavirus in vitro.
Loss of Atg7 causes chaotic nucleosome assembly of mouse bone marrow CD11b+Ly6G- myeloid cells.
RNAi-mediated silencing of Trichinella spiralis serpin-type serine protease inhibitors results in a reduction in larval infectivity.
Calcium and TRPV4 promote metastasis by regulating cytoskeleton through the RhoA/ROCK1 pathway in endometrial cancer.
TDP-43 interacts with amyloid-β, inhibits fibrillization, and worsens pathology in a model of Alzheimer's disease.
MiR-103a-3p promotes tumour glycolysis in colorectal cancer via hippo/YAP1/HIF1A axis.
Inhibition of ferroptosis alleviates atherosclerosis through attenuating lipid peroxidation and endothelial dysfunction in mouse aortic endothelial cell.
Velvet antler polypeptide prevents the disruption of hepatic tight junctions via inhibiting oxidative stress in cholestatic mice and liver cell lines.
The TLR3/IRF1/Type III IFN Axis Facilitates Antiviral Responses against Enterovirus Infections in the Intestine.
Urocortin participates in LPS-induced apoptosis of THP-1 macrophages via S1P-cPLA2 signaling pathway.
Identification and functional analysis of fourteen NR5A1 variants in patients with the 46 XY disorders of sex development.
Inhibiting Rab27a in renal tubular epithelial cells attenuates the inflammation of diabetic kidney disease through the miR-26a-5p/CHAC1/NF-kB pathway.
USP33 regulates c-Met expression by deubiquitinating SP1 to facilitate metastasis in hepatocellular carcinoma.
Macrophage-Derived IL-1β Regulates Emergency Myelopoiesis via the NF-κB and C/ebpβ in Zebrafish.
Targeting HMGB3/hTERT axis for radioresistance in cervical cancer.
Autophagic blockage by bismuth sulfide nanoparticles inhibits migration and invasion of HepG2 cells.
The role of macrophage migration inhibitory factor in promoting benign prostatic hyperplasia epithelial cell growth by modulating COX-2 and P53 signaling.
Electroacupuncture alleviates Parkinson disease and regulates the expression of brain-gut peptides.
Tomatidine inhibits porcine epidemic diarrhea virus replication by targeting 3CL protease.
A CRISPR-Cas9 screen identifies mitochondrial translation as an essential process in latent KSHV infection of human endothelial cells.
Inhibition of notch enhances the anti-atherosclerotic effects of LXR agonists while reducing fatty liver development in ApoE-deficient mice.
Discovery of novel anti-angiogenesis agents. Part 11: Development of PROTACs based on active molecules with potency of promoting vascular normalization.
L-lactate preconditioning promotes plasticity-related proteins expression and reduces neurological deficits by potentiating GPR81 signaling in rat traumatic brain injury model.
Circ-PGAM1 promotes malignant progression of epithelial ovarian cancer through regulation of the miR-542-3p/CDC5L/PEAK1 pathway.
Grape Extract Activates Brown Adipose Tissue Through Pathway Involving the Regulation of Gut Microbiota and Bile Acid.
Lysyl-tRNA synthetase produces diadenosine tetraphosphate to curb STING-dependent inflammation.
CtBP1 transactivates RAD51 and confers cisplatin resistance to breast cancer cells.
TRIM22 inhibits endometrial cancer progression through the NOD2/NF‑κB signaling pathway and confers a favorable prognosis.
Mechanism of aberrant long non-coding RNA expression in an adriamycin-resistant liver cancer cell strain.
MicroRNA‑145‑5p inhibits osteosarcoma cell proliferation by targeting E2F transcription factor 3.
DNA methylation‑regulated miR‑155‑5p depresses sensitivity of esophageal carcinoma cells to radiation and multiple chemotherapeutic drugs via suppression of MAP3K10.
Ganoderic acid hinders renal fibrosis via suppressing the TGF-β/Smad and MAPK signaling pathways.
PBX1 promotes development of natural killer cells by binding directly to the Nfil3 promoter.
Cognitive improvement and synaptic deficit attenuation by a multifunctional carbazole-based cyanine in AD mice model through regulation of Ca2+/CaMKII/CREB signaling pathway.
Yeast β-D-glucan exerts antitumour activity in liver cancer through impairing autophagy and lysosomal function, promoting reactive oxygen species production and apoptosis.
BMX activates Wnt/β-catenin signaling pathway to promote cell proliferation and migration in breast cancer.
Autophagy related 4B, upregulated by HIF-1α, attenuates the sensitivity to cisplatin in nasopharyngeal carcinoma cells.
LncRNA ZEB2-AS1 promotes the proliferation, migration and invasion of esophageal squamous cell carcinoma cell through miR-574-3p/HMGA2 axis.
miR-181a/b-5p ameliorates inflammatory response in monocrotaline-induced pulmonary arterial hypertension by targeting endocan.
Altered circadian clock as a novel therapeutic target for constant darkness-induced insulin resistance and hyperandrogenism of polycystic ovary syndrome.
Mitophagy is involved in chromium (VI)-induced mitochondria damage in DF-1 cells.
Chlorogenic acid rescues zearalenone induced injury to mouse ovarian granulosa cells.
SOX9 represses hepatitis B virus replication through binding to HBV EnhII/Cp and inhibiting the promoter activity.
Modulation of NR1 receptor by CaMKIIα plays an important role in chronic itch development in mice.
RIP3/MLKL-mediated neuronal necroptosis induced by methamphetamine at 39°C.
Activation of sirtuin1 protects against ischemia/reperfusion-induced acute kidney injury.
The natural compound andrographolide inhibits human aortic valve interstitial cell calcification via the NF-kappa B/Akt/ERK pathway.
Melanoma suppression by quercein is correlated with RIG-I and type I interferon signaling.
Silencing METTL3 inhibits the proliferation and invasion of osteosarcoma by regulating ATAD2.
ALDH1A1 maintains the cancer stem-like cells properties of esophageal squamous cell carcinoma by activating the AKT signal pathway and interacting with β-catenin.
Upregulation of nuclear factor (erythroid-derived 2)-like 2 protein level in the human colorectal adenocarcinoma cell line DLD-1 by a heterocyclic organobismuth(III) compound: Effect of organobismuth(III) compound on NRF2 signaling.
KIF2A promotes the progression via AKT signaling pathway and is upregulated by transcription factor ETV4 in human gastric cancer.
β-elemene suppresses the malignant behavior of esophageal cancer cells by regulating the phosphorylation of AKT.
DACT2 regulates structural and electrical atrial remodeling in atrial fibrillation.
Protein kinase CK2 participates in estrogen-mediated endothelial progenitor cell homing to endometriotic lesions through stromal cells in a stromal cell-derived factor-1- CXCR4-dependent manner.
BMP8A promotes survival and drug resistance via Nrf2/TRIM24 signaling pathway in clear cell renal cell carcinoma.
Epithelial V-like antigen 1 promotes hepatocellular carcinoma growth and metastasis via the ERBB-PI3K-AKT pathway.
Hydrogen inhibits the osteoclastogenesis of mouse bone marrow mononuclear cells.
Whole transcriptome sequencing reveals dexmedetomidine-improves postoperative cognitive dysfunction in rats via modulating lncRNA.
Morphometric, Hemodynamic, and Multi-Omics Analyses in Heart Failure Rats with Preserved Ejection Fraction.
Rapid Neutralization Testing System for Zika Virus Based on an Enzyme-Linked Immunospot Assay.
Perturbation of phosphoglycerate kinase 1 (PGK1) only marginally affects glycolysis in cancer cells.
PHLDA2 regulates EMT and autophagy in colorectal cancer via the PI3K/AKT signaling pathway.
Analysis of the role of the interleukins in colon cancer.
Neuropeptide Y1 receptor antagonist promotes osteoporosis and microdamage repair and enhances osteogenic differentiation of bone marrow stem cells via cAMP/PKA/CREB pathway.
Self-responsive co-delivery system for remodeling tumor intracellular microenvironment to promote PTEN-mediated anti-tumor therapy.
Small-molecule inhibition of aging-associated chromosomal instability delays cellular senescence.
Naringin inhibits autophagy mediated by PI3K-Akt-mTOR pathway to ameliorate endothelial cell dysfunction induced by high glucose/high fat stress.
Downregulation of GLYR1 contributes to microsatellite instability colorectal cancer by targeting p21 via the p38MAPK and PI3K/AKT pathways.
Kalirin Interacts with TRAPP and Regulates Rab11 and Endosomal Recycling.
The heterocyclic compound Tempol inhibits the growth of cancer cells by interfering with glutamine metabolism.
Prenatal bisphenol A exposure contributes to Tau pathology: Potential roles of CDK5/GSK3β/PP2A axis in BPA-induced neurotoxicity.
Pharmacogenomic Analysis Reveals CCNA2 as a Predictive Biomarker of Sensitivity to Polo-Like Kinase I Inhibitor in Gastric Cancer.
Design, Synthesis, and Biological Evaluation of HSP90 Inhibitor-SN38 Conjugates for Targeted Drug Accumulation.
PAX6 contributes to the activation and proliferation of hepatic stellate cells via activating Hedgehog/GLI1 pathway.
Synergistic antifibrotic effects of miR-451 with miR-185 partly by co-targeting EphB2 on hepatic stellate cells.
circStrn3 is involved in bone cancer pain regulation in a rat model.
Circular RNA circNRIP1 promotes migration and invasion in cervical cancer by sponging miR-629-3p and regulating the PTP4A1/ERK1/2 pathway.
Evodiamine via targeting nNOS and AMPA receptor GluA1 inhibits nitroglycerin-induced migraine-like response.
Delivery of oligonucleotides to bone marrow to modulate ferrochelatase splicing in a mouse model of erythropoietic protoporphyria.
Exogenous Therapeutics of Microrna-29a Attenuates Development of Hepatic Fibrosis in Cholestatic Animal Model through Regulation of Phosphoinositide 3-Kinase p85 Alpha.
KMT2A regulates cervical cancer cell growth through targeting VDAC1.
Inhibition of protein phosphatase methylesterase 1 dysregulates MAP kinase signaling and attenuates muscle cell differentiation.
Anti-inflammatory activity of berberine in non-alcoholic fatty liver disease via the Angptl2 pathway.
Fatty Acid Synthase Inhibitor G28 Shows Anticancer Activity in EGFR Tyrosine Kinase Inhibitor Resistant Lung Adenocarcinoma Models.
Bone-targeted lncRNA OGRU alleviates unloading-induced bone loss via miR-320-3p/Hoxa10 axis.
High-mobility group box 1 promotes epithelial-to-mesenchymal transition in crystalline silica induced pulmonary inflammation and fibrosis.
Knockdown of the Ribosomal Protein eL29 in Mammalian Cells Leads to Significant Changes in Gene Expression at the Transcription Level.
TACC3 promotes prostate cancer cell proliferation and restrains primary cilium formation.
Time serial transcriptome reveals Cyp2c29 as a key gene in hepatocellular carcinoma development.
MEL endomorphins act as potent inflammatory analgesics with the inhibition of activated non-neuronal cells and modulation of pro-inflammatory cytokines.
Heterogeneous nuclear ribonucleoprotein A3 controls mitotic progression of neural progenitors via interaction with cohesin.
Quercetin alleviated H2 O2 -induced apoptosis and steroidogenic impairment in goat luteinized granulosa cells.
UBQLN2 Promotes the Production of Type I Interferon via the TBK1-IRF3 Pathway.
Membrane-Associated α-Tubulin Is Less Acetylated in Postmortem Prefrontal Cortex from Depressed Subjects Relative to Controls: Cytoskeletal Dynamics, HDAC6, and Depression.
Discovery of a novel third-generation EGFR inhibitor and identification of a potential combination strategy to overcome resistance.
Evidence for Cytoprotective Effect of Carbon Monoxide Donor in the Development of Acute Esophagitis Leading to Acute Esophageal Epithelium Lesions.
EFEMP2 indicates assembly of M0 macrophage and more malignant phenotypes of glioma.
SETDB1 promotes the progression of colorectal cancer via epigenetically silencing p21 expression.
POTEE promotes colorectal carcinoma progression via activating the Rac1/Cdc42 pathway.
RNA-Seq Reveals Underlying Transcriptomic Mechanisms of Bone Marrow-Derived Mesenchymal Stem Cells in the Regulation of Microglia-Mediated Neuroinflammation After Subarachnoid Hemorrhage.
Type 3 adenylyl cyclase in the main olfactory epithelium participates in depression-like and anxiety-like behaviours.
A modular biomimetic strategy for the synthesis of macrolide P-glycoprotein inhibitors via Rh-catalyzed C-H activation.
Demethyleneberberine attenuates concanavalin A-induced autoimmune hepatitis in mice through inhibition of NF-κB and MAPK signaling.
Downregulation of ubiquitin-specific protease 2 possesses prognostic and diagnostic value and promotes the clear cell renal cell carcinoma progression.
Genome sequencing analysis of a family with a child displaying severe abdominal distention and recurrent hypoglycemia.
Characterization of seminal plasma proteomic alterations associated with the IVF and rescue-ICSI pregnancy in assisted reproduction.
Mouse model of metformin-induced diarrhea.
Rosmarinic acid exerts an anticancer effect on osteosarcoma cells by inhibiting DJ-1 via regulation of the PTEN-PI3K-Akt signaling pathway.
Elevated myocardial SORBS2 and the underlying implications in left ventricular noncompaction cardiomyopathy.
Thymosinβ4 alleviates cholestatic liver fibrosis in mice through downregulating PDGF/PDGFR and TGFβ/Smad pathways.
MicroRNA‑137 suppresses the proliferation, migration and invasion of cholangiocarcinoma cells by targeting WNT2B.
Linc00261 inhibits metastasis and the WNT signaling pathway of pancreatic cancer by regulating a miR‑552‑5p/FOXO3 axis.
Aurora B induces epithelial-mesenchymal transition by stabilizing Snail1 to promote basal-like breast cancer metastasis.
The Wnt/β-catenin/VASP positive feedback loop drives cell proliferation and migration in breast cancer.
Dehydrocostus lactone inhibits NLRP3 inflammasome activation by blocking ASC oligomerization and prevents LPS-mediated inflammation in vivo.
Identification of apoptosis-associated protein factors distinctly expressed in cigarette smoke condensate-exposed airway bronchial epithelial cells.
HUWE1 promotes EGFR ubiquitination and degradation to protect against renal tubulointerstitial fibrosis.
Upregulation of KSRP by miR-27b attenuates schistosomiasis-induced hepatic fibrosis by targeting TGF-β1.
Jmjd3 regulates inflammasome activation and aggravates DSS-induced colitis in mice.
Inflammatory-sensitive CHI3L1 protects nucleus pulposus via AKT3 signaling during intervertebral disc degeneration.
Do You Know the Details of Your PAX8 Antibody? Monoclonal PAX8 (MRQ-50) Is Not Expressed in a Series of 45 Medullary Thyroid Carcinomas.
A serpin from the tick Rhipicephalus haemaphysaloides: Involvement in vitellogenesis.
Atlastin-1 modulates seizure activity and neuronal excitability.
Immunoproteasome subunit β5i regulates diet-induced atherosclerosis through altering MERTK-mediated efferocytosis in Apoe knockout mice.
Rutin promotes osteogenic differentiation of periodontal ligament stem cells through the GPR30-mediated PI3K/AKT/mTOR signaling pathway.
Oxymatrine suppresses IL-1β-induced degradation of the nucleus pulposus cell and extracellular matrix through the TLR4/NF-κB signaling pathway.
Anti-ageing effects of red ginseng on female Drosophila melanogaster.
MiR-133a alleviates renal injury caused by sepsis by targeting BNIP3L.
Dioscin inhibits the growth of human osteosarcoma by inducing G2/M-phase arrest, apoptosis, and GSDME-dependent cell death in vitro and in vivo.
Autophagy inhibition via Becn1 downregulation improves the mesenchymal stem cells antifibrotic potential in experimental liver fibrosis.
Decreasing New York esophageal squamous cell carcinoma 1 expression inhibits multiple myeloma growth and osteolytic lesions.
Silencing of tumor-suppressive NR_023387 in renal cell carcinoma via promoter hypermethylation and HNF4A deficiency.
Polystyrene nanoplastic induces ROS production and affects the MAPK-HIF-1/NFkB-mediated antioxidant system in Daphnia pulex.
The tacrolimus-induced glucose homeostasis imbalance in terms of the liver: From bench to bedside.
miR-181a negatively modulates synaptic plasticity in hippocampal cultures and its inhibition rescues memory deficits in a mouse model of Alzheimer's disease.
Ubiquitination of P53 by E3 ligase MKRN2 promotes melanoma cell proliferation.
MicroRNA-103a-3p potentiates chemoresistance to cisplatin in non-small cell lung carcinoma by targeting neurofibromatosis 1.
The functional role of the C-terminal tail of the human ribosomal protein uS19.
A long noncoding RNA sensitizes genotoxic treatment by attenuating ATM activation and homologous recombination repair in cancers.
Hypericin attenuates nonalcoholic fatty liver disease and abnormal lipid metabolism via the PKA-mediated AMPK signaling pathway in vitro and in vivo.
Synthesis of dual functional procaine-derived carbon dots for bioimaging and anticancer therapy.
Matrix mechanics and water permeation regulate extracellular vesicle transport.
A new abietane diterpenoid from Ajuga ovalifolia var. calantha induces human lung epithelial A549 cell apoptosis by inhibiting SHP2.
LongShengZhi capsule inhibits doxorubicin-induced heart failure by anti-oxidative stress.
DKC1 enhances angiogenesis by promoting HIF-1α transcription and facilitates metastasis in colorectal cancer.
IL1β inhibits differentiation of cementoblasts via microRNA-325-3p.
G protein-coupled receptor kinase-2: A potential biomarker for early diabetic cardiomyopathy.
Cannabinoid receptor 1 knockout alleviates hepatic steatosis by downregulating perilipin 2.
ETS2 promotes epithelial-to-mesenchymal transition in renal fibrosis by targeting JUNB transcription.
MicroRNA-217-5p ameliorates endothelial cell apoptosis induced by ox-LDL by targeting CLIC4.
Melatonin Promotes the Proliferation of Chicken Sertoli Cells by Activating the ERK/Inhibin Alpha Subunit Signaling Pathway.
Molecular hydrogen attenuates methamphetamine-induced behavioral sensitization and activation of ERK-ΔFosB signaling in the mouse nucleus accumbens.
Topology, Antiviral Functional Residues and Mechanism of IFITM1.
Novel HSP90-PI3K Dual Inhibitor Suppresses Melanoma Cell Proliferation by Interfering with HSP90-EGFR Interaction and Downstream Signaling Pathways.
Transcription co-activator P300 activates Elk1-aPKC-ι signaling mediated epithelial-to-mesenchymal transition and malignancy in hepatocellular carcinoma.
Anti-toll-like receptor 2 antibody ameliorates hepatic injury, inflammation, fibrosis and steatosis in obesity-related metabolic disorder rats via regulating MAPK and NF-κB pathways.
Pathway-specific enzymes from bamboo and crop leaves biosynthesize anti-nociceptive C-glycosylated flavones.
Human polymorphisms in GSDMD alter the inflammatory response.
lncRNA RMST Suppressed GBM Cell Mitophagy through Enhancing FUS SUMOylation.
The 25(OH)D/VDR signaling may play a role in major depression.
TRPC6-dependent Ca2+ signaling mediates airway inflammation in response to oxidative stress via ERK pathway.
PTEN inhibitor VO-OHpic attenuates GC-associated endothelial progenitor cell dysfunction and osteonecrosis of the femoral head via activating Nrf2 signaling and inhibiting mitochondrial apoptosis pathway.
Genetic inactivation of mTORC1 or mTORC2 in neurons reveals distinct functions in glutamatergic synaptic transmission.
5-HT1AR alleviates Aβ-induced cognitive decline and neuroinflammation through crosstalk with NF-κB pathway in mice.
Nanofiber Alignment Mediates the Pattern of Single Cell Migration.
Qingyi decoction protects against myocardial injuries induced by severe acute pancreatitis.
The Agpat4/LPA axis in colorectal cancer cells regulates antitumor responses via p38/p65 signaling in macrophages.
Long non-coding RNA HAL suppresses the migration and invasion of serous ovarian cancer by inhibiting EMT signaling pathway.
Posttranslational lysine 2-hydroxyisobutyrylation of human sperm tail proteins affects motility.
The C-terminal domain of feline and bovine SAMHD1 proteins has a crucial role in lentiviral restriction.
Design, Synthesis, and Biological Evaluation of Imidazo[1,2-a]pyridine Derivatives as Novel PI3K/mTOR Dual Inhibitors.
Changed PGA and POSTN levels in choroid plexus are associated with depressive-like behaviors in mice.
KLF5 Is Crucial for Androgen-AR Signaling to Transactivate Genes and Promote Cell Proliferation in Prostate Cancer Cells.
Dual regulation of p53 by the ribosome maturation factor SBDS.
Cervical carcinoma risk associate with genetic polymorphisms of NEIL2 gene in Chinese population and its significance as predictive biomarker.
Inhibiting both proline biosynthesis and lipogenesis synergistically suppresses tumor growth.
Complement Signals Determine Opposite Effects of B Cells in Chemotherapy-Induced Immunity.
AQP1 modulates tendon stem/progenitor cells senescence during tendon aging.
ADORA1 Inhibition Promotes Tumor Immune Evasion by Regulating the ATF3-PD-L1 Axis.
PHLDA1 is a new therapeutic target of oxidative stress and ischemia reperfusion-induced myocardial injury.
Design, synthesis, biological evaluation of 6-(2-amino-1H-benzo[d]imidazole-6-yl)quinazolin-4(3H)-one derivatives as novel anticancer agents with Aurora kinase inhibition.
Mesencephalic astrocyte-derived neurotrophic factor ameliorates steatosis in HepG2 cells by regulating hepatic lipid metabolism.
Pellino1 regulates neuropathic pain as well as microglial activation through the regulation of MAPK/NF-κB signaling in the spinal cord.
Western diet induces severe nonalcoholic steatohepatitis, ductular reaction, and hepatic fibrosis in liver CGI-58 knockout mice.
Dietary Compound Isoliquiritigenin, an Antioxidant from Licorice, Suppresses Triple-Negative Breast Tumor Growth via Apoptotic Death Program Activation in Cell and Xenograft Animal Models.
Controlled release of adenosine from core-shell nanofibers to promote bone regeneration through STAT3 signaling pathway.
LncRNA HCP5 promotes cell proliferation and inhibits apoptosis via miR-27a-3p/IGF-1 axis in human granulosa-like tumor cell line KGN.
AEBP1 Promotes the Occurrence and Development of Abdominal Aortic Aneurysm by Modulating Inflammation via the NF-κB Pathway.
Microcystins-LR induced apoptosis via S-nitrosylation of GAPDH in colorectal cancer cells.
miR-144 Mediates High Fat-Induced Changes of Cholesterol Metabolism via Direct Regulation of C/EBPα in the Liver and Isolated Hepatocytes of Yellow Catfish.
Suppression of high-mobility group box 1 ameliorates xerostomia in a Sjögren syndrome-triggered mouse model.
Nbr1-regulated autophagy in Lactoferrin-induced osteoblastic differentiation.
Antibody microarray analysis of serum inflammatory cytokines in patients with calcific aortic valve disease.
Fam83d modulates MAP kinase and AKT signaling and is induced during neurogenic skeletal muscle atrophy.
Expression, location and biological effects of four and a half LIM domain protein 2 (FHL2) on granulosa cells in ovine.
TNF-α/HMGB1 inflammation signalling pathway regulates pyroptosis during liver failure and acute kidney injury.
TGM3 promotes epithelial-mesenchymal transition and hepatocellular carcinogenesis and predicts poor prognosis for patients after curative resection.
Enhanced tenogenic differentiation and tendon-like tissue formation by Scleraxis overexpression in human amniotic mesenchymal stem cells.
Effects of hyperoxia exposure on the expression of Nrf2 and heme oxygenase-1 in lung tissues of premature rats.
EMT related circular RNA expression profiles identify circSCYL2 as a novel molecule in breast tumor metastasis.
Alda-1, an Aldehyde Dehydrogenase 2 Agonist, Improves Cutaneous Wound Healing by Activating Epidermal Keratinocytes via Akt/GSK-3β/β-Catenin Pathway.
Leucine-rich repeat containing 4 act as an autophagy inhibitor that restores sensitivity of glioblastoma to temozolomide.
Altered expression of AKT1 and P38A in the colons of patients with Hirschsprung's disease.
Ghrelin promotes neural differentiation of adipose tissue-derived mesenchymal stem cell via AKT/mTOR and β-catenin signaling pathways.
Berardinelli-Seip congenital lipodystrophy 2/SEIPIN determines brown adipose tissue maintenance and thermogenic programing.
Neuroprotective effects of miR-532-5p against ischemic stroke.
Upregulation of miR-219a-5p Decreases Cerebral Ischemia/Reperfusion Injury In Vitro by Targeting Pde4d.
Integrin β3, a RACK1 interacting protein, is critical for porcine reproductive and respiratory syndrome virus infection and NF-κB activation in Marc-145 cells.
The E3 ubiquitin ligase TRIM7 suppressed hepatocellular carcinoma progression by directly targeting Src protein.
Inflammatory injury and mitophagy induced by Cr(VI) in chicken liver.
Knockdown of p66ShcA activates Nrf2 pathway to protect cardiomyocytes from oxidative stress and inflammation induced by H2O2.
MiR-126 regulated myocardial autophagy on myocardial infarction.
Seizure-induced impairment in neuronal ketogenesis: Role of zinc-α2-glycoprotein in mitochondria.
Endogenous thrombopoietin promotes non-small-cell lung carcinoma cell proliferation and migration by regulating EGFR signalling.
A study of the effects of SGLT-2 inhibitors on diabetic cardiomyopathy through miR-30d/KLF9/VEGFA pathway.
Analysis of deep sequencing exosome-microRNA expression profile derived from CP-II reveals potential role of gga-miRNA-451 in inflammation.
An upstream open reading frame regulates vasculogenic mimicry of glioma via ZNRD1-AS1/miR-499a-5p/ELF1/EMI1 pathway.
Rice Protein Exerts Endogenous Antioxidant Capacity via Methionine Sulfoxide Reductase and the Nrf2 Antioxidant System Independent of Age.
BMP4 resets mouse epiblast stem cells to naive pluripotency through ZBTB7A/B-mediated chromatin remodelling.
MicroRNA‑28 promotes the proliferation of non‑small‑cell lung cancer cells by targeting PTEN.
Bisphenol a affects endometrial stromal cells decidualization, involvement of epigenetic regulation.
Biointerface anisotropy modulates migration of breast cancer cell.
PTPN3 Inhibits the Growth and Metastasis of Clear Cell Renal Cell Carcinoma via Inhibition of PI3K/AKT Signaling.
Meprin-α (Mep1A) enhances TNF-α secretion by mast cells and aggravates abdominal aortic aneurysms.
DHA attenuates Aβ-induced necroptosis through the RIPK1/RIPK3 signaling pathway in THP-1 monocytes.
Modified citrus pectin ameliorates myocardial fibrosis and inflammation via suppressing galectin-3 and TLR4/MyD88/NF-κB signaling pathway.
Interference with SMO increases chemotherapy drug sensitivity of A2780/DDP cells by inhibiting the Hh/Gli signaling pathway.
Long noncoding RNA linc00467 plays an oncogenic role in hepatocellular carcinoma by regulating the miR-18a-5p/NEDD9 axis.
Activator of thyroid and retinoid receptor increases sorafenib resistance in hepatocellular carcinoma by facilitating the Warburg effect.
Oxidative stress induces monocyte-to-myofibroblast transdifferentiation through p38 in pancreatic ductal adenocarcinoma.
T-cell activation and immune memory enhancement induced by irreversible electroporation in pancreatic cancer.
The effect of swimming exercise and diet on the hypothalamic inflammation of ApoE-/- mice based on SIRT1-NF-κB-GnRH expression.
Highly expressed STAT1 contributes to the suppression of stemness properties in human paclitaxel-resistant ovarian cancer cells.
Gan Shen Fu Fang ameliorates liver fibrosis in vitro and in vivo by inhibiting the inflammatory response and extracellular signal-regulated kinase phosphorylation.
Progranulin inhibits LPS-induced macrophage M1 polarization via NF-кB and MAPK pathways.
Role of ANKHD1/LINC00346/ZNF655 Feedback Loop in Regulating the Glioma Angiogenesis via Staufen1-Mediated mRNA Decay.
lncRNA LINC00665 Stabilized by TAF15 Impeded the Malignant Biological Behaviors of Glioma Cells via STAU1-Mediated mRNA Degradation.
Minocycline alleviates NLRP3 inflammasome-dependent pyroptosis in monosodium glutamate-induced depressive rats.
Loss of CHCHD2 and CHCHD10 activates OMA1 peptidase to disrupt mitochondrial cristae phenocopying patient mutations.
Integrative Analysis of NSCLC Identifies LINC01234 as an Oncogenic lncRNA that Interacts with HNRNPA2B1 and Regulates miR-106b Biogenesis.
SRSF10 inhibits biogenesis of circ-ATXN1 to regulate glioma angiogenesis via miR-526b-3p/MMP2 pathway.
Deletion of the Impg2 gene causes the degeneration of rod and cone cells in mice.
Pyrroloquinoline Quinone Inhibits Oxidative Stress in Rats with Diabetic Nephropathy.
Cimifugin ameliorates imiquimod-induced psoriasis by inhibiting oxidative stress and inflammation via NF-κB/MAPK pathway.
STEAP1 facilitates metastasis and epithelial-mesenchymal transition of lung adenocarcinoma via the JAK2/STAT3 signaling pathway.
Chi-miR-30b-5p inhibits dermal papilla cells proliferation by targeting CaMKIIδ gene in cashmere goat.
The PABPC5/HCG15/ZNF331 Feedback Loop Regulates Vasculogenic Mimicry of Glioma via STAU1-Mediated mRNA Decay.
Overexpression of YBX1 Promotes Pancreatic Ductal Adenocarcinoma Growth via the GSK3B/Cyclin D1/Cyclin E1 Pathway.
RBFOX1 Regulates the Permeability of the Blood-Tumor Barrier via the LINC00673/MAFF Pathway.
MicroRNA-675-3p regulates IL-1β-stimulated human chondrocyte apoptosis and cartilage degradation by targeting GNG5.
Circular RNA circ_0111277 attenuates human trophoblast cell invasion and migration by regulating miR-494/HTRA1/Notch-1 signal pathway in pre-eclampsia.
Targeted Delivery of Notch Inhibitor Attenuates Obesity-Induced Glucose Intolerance and Liver Fibrosis.
α7nAchR mediates transcutaneous auricular vagus nerve stimulation-induced neuroprotection in a rat model of ischemic stroke by enhancing axonal plasticity.
Analysis of RAS protein interactions in living cells reveals a mechanism for pan-RAS depletion by membrane-targeted RAS binders.
Immune activation of murine RAW264.7 macrophages by sonicated and alkalized paramylon from Euglena gracilis.
LUZP1, a novel regulator of primary cilia and the actin cytoskeleton, is a contributing factor in Townes-Brocks Syndrome.
Long noncoding RNA LINC00314 facilitates osteogenic differentiation of adipose-derived stem cells through the hsa-miR-129-5p/GRM5 axis via the Wnt signaling pathway.
Pannexin1 Channel Inhibitor (10panx) Protects Against Transient Focal Cerebral Ischemic Injury by Inhibiting RIP3 Expression and Inflammatory Response in Rats.
IL-4 Switches Microglia/macrophage M1/M2 Polarization and Alleviates Neurological Damage by Modulating the JAK1/STAT6 Pathway Following ICH.
Perinatal low-dose PBDE-47 exposure hampered thyroglobulin turnover and induced thyroid cell apoptosis by triggering ER stress and lysosomal destabilization contributing to thyroid toxicity in adult female rats.
β-catenin-mediated Wnt signal transduction proceeds through an endocytosis-independent mechanism.
Major depression accompanied with inflammation and multiple cytokines alterations: Evidences from clinical patients to macaca fascicularis and LPS-induced depressive mice model.
PLK1 Inhibition alleviates transplant-associated obliterative bronchiolitis by suppressing myofibroblast differentiation.
Non-Esterified Fatty Acid-Induced Reactive Oxygen Species Mediated Granulosa Cells Apoptosis Is Regulated by Nrf2/p53 Signaling Pathway.
Qian Yang Yu Yin Granule protects against hypertension-induced renal injury by epigenetic mechanism linked to Nicotinamide N-Methyltransferase (NNMT) expression.
Ginsenoside Rg3 promotes regression from hepatic fibrosis through reducing inflammation-mediated autophagy signaling pathway.
Circular RNA circZNF566 promotes hepatocellular carcinoma progression by sponging miR-4738-3p and regulating TDO2 expression.
TSPO ligand Ro5-4864 modulates microglia/macrophages polarization after subarachnoid hemorrhage in mice.
Knockdown of fibronectin extra domain B suppresses TGF-β1-mediated cell proliferation and collagen deposition in keloid fibroblasts via AKT/ERK signaling pathway.
Circular RNA (circRNA) CDYL Induces Myocardial Regeneration by ceRNA After Myocardial Infarction.
M6A-related bioinformatics analysis reveals that HNRNPC facilitates progression of OSCC via EMT.
Extrasynaptic CaMKIIα is involved in the antidepressant effects of ketamine by downregulating GluN2B receptors in an LPS-induced depression model.
SHQ1 is an ER stress response gene that facilitates chemotherapeutics-induced apoptosis via sensitizing ER-stress response.
Denatured Collagen Could Increase the Autophagy Level and Inhibit Apoptosis of Fibroblasts to Help Cell Survival and Influence Wound Healing.
Downregulation of BACH1 Protects AGAINST Cerebral Ischemia/Reperfusion Injury through the Functions of HO-1 and NQO1.
Phenylephrine alleviates 131I damage in submandibular gland through promoting endogenous stem cell regeneration via lissencephaly-1 upregulation.
DNMT1-mediated Foxp3 gene promoter hypermethylation involved in immune dysfunction caused by arsenic in human lymphocytes.
ARHGEF10L expression regulates cell proliferation and migration in gastric tumorigenesis.
Costunolide improved dextran sulfate sodium-induced acute ulcerative colitis in mice through NF-κB, STAT1/3, and Akt signaling pathways.
Acarbose, as a potential drug, effectively blocked the dynamic metastasis of EV71 from the intestine to the whole body.
A mitophagic response to iron overload-induced oxidative damage associated with the PINK1/Parkin pathway in pancreatic beta cells.
Generation of B6-Ddx4em1(CreERT2)Utr , a novel CreERT2 knock-in line, for germ cell lineage by CRISPR/Cas9.
Crocin Reverses Depression-Like Behavior in Parkinson Disease Mice via VTA-mPFC Pathway.
HSulf‑1 and palbociclib exert synergistic antitumor effects on RB‑positive triple‑negative breast cancer.
Circulating Exosomes From Lipopolysaccharide-Induced Ards Mice Trigger Endoplasmic Reticulum Stress in Lung Tissue.
Matrix Metalloproteinase 11 as a Novel Tumor Promoter and Diagnostic and Prognostic Biomarker for Pancreatic Ductal Adenocarcinoma.
Methionine Enkephalin Suppresses Osteocyte Apoptosis Induced by Compressive Force through Regulation of Nuclear Translocation of NFATc1.
S100A14 suppresses metastasis of nasopharyngeal carcinoma by inhibition of NF-kB signaling through degradation of IRAK1.
Transcription factorIRX5 promotes hepatocellular carcinoma proliferation and inhibits apoptosis by regulating the p53 signalling pathway.
Thyrotropin receptor signaling deficiency impairs spatial learning and memory in mice.
Porcine RACK1 negatively regulates the infection of classical swine fever virus and the NF-κB activation in PK-15 cells.
UHRF1 predicts poor prognosis by triggering cell cycle in lung adenocarcinoma.
p75NTR optimizes the osteogenic potential of human periodontal ligament stem cells by up-regulating α1 integrin expression.
Progress in the research of p53 tumour suppressor activity controlled by Numb in triple-negative breast cancer.
Autophagy assuages myocardial infarction through Nrf2 signaling activation-mediated reactive oxygen species clear.
Reversal of prolonged obesity-associated cerebrovascular dysfunction by inhibiting microglial Tak1.
Wnt10b-overexpressing umbilical cord mesenchymal stem cells promote critical size rat calvarial defect healing by enhanced osteogenesis and VEGF-mediated angiogenesis.
Antioxidant-related catalase CTA1 regulates development, aflatoxin biosynthesis, and virulence in pathogenic fungus Aspergillus flavus.
High expression of CDCA7 predicts tumor progression and poor prognosis in human colorectal cancer.
MicroRNA‑93 promotes angiogenesis and attenuates remodeling via inactivation of the Hippo/Yap pathway by targeting Lats2 after myocardial infarctionω.
LncRNA MALAT1 affects the migration and invasion of trophoblast cells by regulating FOS expression in early-onset preeclampsia.
Metastasis-associated gene MAPK15 promotes the migration and invasion of osteosarcoma cells via the c-Jun/MMPs pathway.
PRR11 and SKA2 promote the proliferation, migration and invasion of esophageal carcinoma cells.
miR-96-5p regulated TGF-β/SMAD signaling pathway and suppressed endometrial cell viability and migration via targeting TGFBR1.
GL-V9 reverses adriamycin resistance in hepatocellular carcinoma cells by affecting JNK2-related autophagy.
Artemisinin inhibits the replication of flaviviruses by promoting the type I interferon production.
Label-Free Quantitative Proteomic Profiling of LAD2 Mast Cell Releasates Reveals the Mechanism of Tween-80-Induced Anaphylactoid Reaction.
miR-429-CRKL axis regulates clear cell renal cell carcinoma malignant progression through SOS1/MEK/ERK/MMP2/MMP9 pathway.
Isocitrate dehydrogenase 2 contributes to radiation resistance of oesophageal squamous cell carcinoma via regulating mitochondrial function and ROS/pAKT signalling.
Integration of in vitro data from three dimensionally cultured HepaRG cells and physiologically based pharmacokinetic modeling for assessment of acetaminophen hepatotoxicity.
High expression of KITLG is a new hallmark activating the MAPK pathway in type A and AB thymoma.
RDP3, A Novel Antigout Peptide Derived from Water Extract of Rice.
Matrine inhibits the growth of natural killer/T-cell lymphoma cells by modulating CaMKIIγ-c-Myc signaling pathway.
Opposing biological functions of the cytoplasm and nucleus DAXX modified by SUMO-2/3 in gastric cancer.
κB-Ras and Ral GTPases regulate acinar to ductal metaplasia during pancreatic adenocarcinoma development and pancreatitis.
Cerebral Blood Flow-Guided Manipulation of Arterial Blood Pressure Attenuates Hippocampal Apoptosis After Asphyxia-Induced Cardiac Arrest in Rats.
CXCL5 promotes gastric cancer metastasis by inducing epithelial-mesenchymal transition and activating neutrophils.
TRIM24 facilitates antiviral immunity through mediating K63-linked TRAF3 ubiquitination.
Synthesis of a Hexavalent Betulinic Acid Derivative as a Hemagglutinin-Targeted Influenza Virus Entry Inhibitor.
Spermidine activates RIP1 deubiquitination to inhibit TNF-α-induced NF-κB/p65 signaling pathway in osteoarthritis.
Loss of HMGCS2 Enhances Lipogenesis and Attenuates the Protective Effect of the Ketogenic Diet in Liver Cancer.
Apoptotic neurodegeneration in whitefly promotes the spread of TYLCV.
Assessment of insulin resistance in the skeletal muscle of mice using positron emission tomography/computed tomography imaging.
Application of Antibodies to Neuronally Expressed Nogo-A Increases Neuronal Survival and Neurite Outgrowth.
EN2 as an oncogene promotes tumor progression via regulating CCL20 in colorectal cancer.
MCF7 Spheroid Development: New Insight about Spatio/Temporal Arrangements of TNTs, Amyloid Fibrils, Cell Connections, and Cellular Bridges.
LncRNA PVT1 promotes gemcitabine resistance of pancreatic cancer via activating Wnt/β-catenin and autophagy pathway through modulating the miR-619-5p/Pygo2 and miR-619-5p/ATG14 axes.
Sensitive Signal Amplifying a Diagnostic Biochip Based on a Biomimetic Periodic Nanostructure for Detecting Cancer Exosomes.
CircATRNL1 promotes epithelial-mesenchymal transition in endometriosis by upregulating Yes-associated protein 1 in vitro.
The Impact of ALS-Associated Genes hnRNPA1, MATR3, VCP and UBQLN2 on the Severity of TDP-43 Aggregation.
mTORC1-dependent TFEB nucleus translocation and pro-survival autophagy induced by zeolitic imidazolate framework-8.
Suppression of PTTG1 inhibits cell angiogenesis, migration and invasion in glioma cells.
Correlation between the HIF-1α/Notch signaling pathway and Modic changes in nucleus pulposus cells isolated from patients with low back pain.
Gold Nanoparticles Induce Tumor Vessel Normalization and Impair Metastasis by Inhibiting Endothelial Smad2/3 Signaling.
Structural and Biological Basis of Alphacoronavirus nsp1 Associated with Host Proliferation and Immune Evasion.
The cross-talk between DDR1 and STAT3 promotes the development of hepatocellular carcinoma.
Histone deacetylase 4 inhibits NF-κB activation by facilitating IκBα sumoylation.
FLIM-FRET-Based Structural Characterization of a Class-A GPCR Dimer in the Cell Membrane.
Glucosylation by the Legionella Effector SetA Promotes the Nuclear Localization of the Transcription Factor TFEB.
LINC00266-1/miR-548c-3p/SMAD2 feedback loop stimulates the development of osteosarcoma.
Ddx56 maintains proliferation of mouse embryonic stem cells via ribosome assembly and interaction with the Oct4/Sox2 complex.
The food contaminant deoxynivalenol provokes metabolic impairments resulting in non-alcoholic fatty liver (NAFL) in mice.
Reduced intracellular chloride concentration impairs angiogenesis by inhibiting oxidative stress-mediated VEGFR2 activation.
CTCF promotes colorectal cancer cell proliferation and chemotherapy resistance to 5-FU via the P53-Hedgehog axis.
Leukemogenic Chromatin Alterations Promote AML Leukemia Stem Cells via a KDM4C-ALKBH5-AXL Signaling Axis.
SIRT1 alleviates high-magnitude compression-induced senescence in nucleus pulposus cells via PINK1-dependent mitophagy.
The urea transporter UT-A1 plays a predominant role in a urea-dependent urine-concentrating mechanism.
A Nimbolide-Based Kinase Degrader Preferentially Degrades Oncogenic BCR-ABL.
RNF126-Mediated Reubiquitination Is Required for Proteasomal Degradation of p97-Extracted Membrane Proteins.
Intracellular expression of arginine deiminase activates the mitochondrial apoptosis pathway by inhibiting cytosolic ferritin and inducing chromatin autophagy.
BMMSC-sEV-derived miR-328a-3p promotes ECM remodeling of damaged urethral sphincters via the Sirt7/TGFβ signaling pathway.
Nedd8-activating enzyme inhibitor MLN4924 (Pevonedistat), inhibits miR-1303 to suppress human breast cancer cell proliferation via targeting p27Kip1.
Effective-component compatibility of Bufei Yishen formula II inhibits mucus hypersecretion of chronic obstructive pulmonary disease rats by regulating EGFR/PI3K/mTOR signaling.
ZIC2 is downregulated and represses tumor growth via the regulation of STAT3 in breast cancer.
Excessive Polyamine Generation in Keratinocytes Promotes Self-RNA Sensing by Dendritic Cells in Psoriasis.
Circular RNA CDR1as Exerts Oncogenic Properties Partially through Regulating MicroRNA 641 in Cholangiocarcinoma.
CPEB3 inhibits epithelial-mesenchymal transition by disrupting the crosstalk between colorectal cancer cells and tumor-associated macrophages via IL-6R/STAT3 signaling.
Synaptopodin-2 promotes hepatocellular carcinoma metastasis via calcineurin-induced nuclear-cytoplasmic translocation.
ETV4 is a theranostic target in clear cell renal cell carcinoma that promotes metastasis by activating the pro-metastatic gene FOSL1 in a PI3K-AKT dependent manner.
MiR-920 promotes osteogenic differentiation of human bone mesenchymal stem cells by targeting HOXA7.
TCF7L2 rs290487 C allele aberrantly enhances hepatic gluconeogenesis through allele-specific changes in transcription and chromatin binding.
GABRG2 Deletion Linked to Genetic Epilepsy with Febrile Seizures Plus Affects the Expression of GABAA Receptor Subunits and Other Genes at Different Temperatures.
miR-744-5p mediates lncRNA HOTTIP to regulate the proliferation and apoptosis of papillary thyroid carcinoma cells.
Erythropoietin-producing hepatocellular receptor A7 restrains estrogen negative feedback of luteinizing hormone via ephrin A5 in the hypothalamus of female rats.
Circulating extracellular vesicles from patients with valvular heart disease induce neutrophil chemotaxis via FOXO3a and the inhibiting role of dexmedetomidine.
A role of the frontotemporal lobar degeneration risk factor TMEM106B in myelination.
Changes in Nup62 content affect contact-induced differentiation of cultured myoblasts.
LncRNA MBNL1-AS1 represses cell proliferation and enhances cell apoptosis via targeting miR-135a-5p/PHLPP2/FOXO1 axis in bladder cancer.
Microglial activation contributes to depressive-like behavior in dopamine D3 receptor knockout mice.
CHK2-FOXK axis promotes transcriptional control of autophagy programs.
MiR-let-7d-3p regulates IL-17 expression through targeting AKT1/mTOR signaling in CD4+ T cells.
PRRX1-induced epithelial-to-mesenchymal transition in salivary adenoid cystic carcinoma activates the metabolic reprogramming of free fatty acids to promote invasion and metastasis.
SIRT3 promotes the invasion and metastasis of cervical cancer cells by regulating fatty acid synthase.
The aqueous extract of Gentianella acuta improves isoproterenol‑induced myocardial fibrosis via inhibition of the TGF‑β1/Smads signaling pathway.
RNA-binding motif protein 10 induces apoptosis and suppresses proliferation by activating p53.
Dichloroacetate restores colorectal cancer chemosensitivity through the p53/miR-149-3p/PDK2-mediated glucose metabolic pathway.
Autophagy and Ubiquitin-Proteasome System Coordinate to Regulate the Protein Quality Control of Neurodegenerative Disease-Associated DCTN1.
Fabrication of porous bovine pericardium scaffolds incorporated with bFGF for tissue engineering applications.
MiR-146a down-regulates inflammatory response by targeting TLR3 and TRAF6 in Coxsackievirus B infection.
In utero hypoxia altered Ang II-induced contraction via PKCβ in fetal cerebral arteries.
Hic-5 deficiency protects cerulein-induced chronic pancreatitis via down-regulation of the NF-κB (p65)/IL-6 signalling pathway.
MicroRNA-29b-3p suppresses oral squamous cell carcinoma cell migration and invasion via IL32/AKT signalling pathway.
Protective mechanism of SIRT1 on Hcy-induced atrial fibrosis mediated by TRPC3.
Long noncoding RNA MAGI1-IT1 regulates cardiac hypertrophy by modulating miR-302e/DKK1/Wnt/beta-catenin signaling pathway.
Targeting the WEE1 kinase strengthens the antitumor activity of imatinib via promoting KIT autophagic degradation in gastrointestinal stromal tumors.
Exome sequencing revealed Notch ligand JAG1 as a novel candidate gene for familial exudative vitreoretinopathy.
Activity and mechanism of flavokawain A in inhibiting P-glycoprotein expression in paclitaxel resistance of lung cancer.
Receptor tyrosine kinase inhibitors block proliferation of TGEV mainly through p38 mitogen-activated protein kinase pathways.
Functional heritage: the evolution of chimeric RNA into a gene.
Activation of PPARA-mediated autophagy reduces Alzheimer disease-like pathology and cognitive decline in a murine model.
FGF9 knockout in GABAergic neurons induces apoptosis and inflammation via the Fas/caspase-3 pathway in the cerebellum of mice.
Alpha-hemolysin of uropathogenic Escherichia coli induces GM-CSF-mediated acute kidney injury.
Osthole inhibits cell proliferation by regulating the TGF-β1/Smad/p38 signaling pathways in pulmonary arterial smooth muscle cells.
Long noncoding RNA CASC21 exerts an oncogenic role in colorectal cancer through regulating miR-7-5p/YAP1 axis.
Convallatoxin induces HaCaT cell necroptosis and ameliorates skin lesions in psoriasis-like mouse models.
Involvement of the p38 MAPK-pHsp27 pathway in vascular hyporeactivity induced by obstructive jaundice in rats.
Resveratrol induces depletion of TRAF6 and suppresses prostate cancer cell proliferation and migration.
Anti-inflammation effects of injectable platelet-rich fibrin via macrophages and dendritic cells.
Overexpression of human wtTDP-43 causes impairment in hippocampal plasticity and behavioral deficits in CAMKII-tTa transgenic mouse model.
Tamoxifen induces fatty liver disease in breast cancer through the MAPK8/FoxO pathway.
SLC6A8 Knockdown Suppresses the Invasion and Migration of Human Hepatocellular Carcinoma Huh-7 and Hep3B Cells.
Desloratadine, a Novel Antigrowth Reagent for Bladder Cancer.
c-Abl-p38α signaling pathway mediates dopamine neuron loss in trigeminal neuralgia.
Satellite glial cells in sensory ganglia express functional transient receptor potential ankyrin 1 that is sensitized in neuropathic and inflammatory pain.
Chemokine receptor CXCR4 activates the RhoA/ROCK2 pathway in spinal neurons that induces bone cancer pain.
Scorpion alleviates bone cancer pain through inhibition of bone destruction and glia activation.
STAT3 Activation-Induced Fatty Acid Oxidation in CD8+ T Effector Cells Is Critical for Obesity-Promoted Breast Tumor Growth.
CD2AP links actin to PI3 kinase activity to extend epithelial cell height and constrain cell area.
A novel IFNα-induced long noncoding RNA negatively regulates immunosuppression by interrupting H3K27 acetylation in head and neck squamous cell carcinoma.
An Alu Element Insertion in Intron 1 Results in Aberrant Alternative Splicing of APOBEC3G Pre-mRNA in Northern Pig-Tailed Macaques (Macaca leonina) That May Reduce APOBEC3G-Mediated Hypermutation Pressure on HIV-1.
Isoliquiritigenin inhibits the proliferation, migration and metastasis of Hep3B cells via suppressing cyclin D1 and PI3K/AKT pathway.
17β-estradiol binding to ERα promotes the progression of prolactinoma through estrogen-response element-induced CaBP-9k up-regulation.
ADAM12 is A Potential Therapeutic Target Regulated by Hypomethylation in Triple-Negative Breast Cancer.
The synthetic cannabinoid dehydroxylcannabidiol restores the function of a major GABAA receptor isoform in a cell model of hyperekplexia.
Inhibition of long non-coding RNA metastasis-associated lung adenocarcinoma transcript 1 attenuates high glucose-induced cardiomyocyte apoptosis via regulation of miR-181a-5p.
Hedgehog signaling promotes sorafenib resistance in hepatocellular carcinoma patient-derived organoids.
Mechanical force regulation of YAP by F-actin and GPCR revealed by super-resolution imaging.
Scutellarin inhibition of the rosuvastatin uptake in rat hepatocytes and the competition for organic anion transporting polypeptide 1B1 in HEK293T cells.
Proteomic and lipidomic analysis of exosomes derived from ovarian cancer cells and ovarian surface epithelial cells.
Inhibitory Activity of a Scorpion Defensin BmKDfsin3 against Hepatitis C Virus.
Photocrosslinking Activity-Based Probes for Ubiquitin RING E3 Ligases.
Dysregulation of BDNF/TrkB signaling mediated by NMDAR/Ca2+/calpain might contribute to postoperative cognitive dysfunction in aging mice.
High RhCG expression predicts poor survival and promotes migration and proliferation of gastric cancer via keeping intracellular alkaline.
linc01088 promotes cell proliferation by scaffolding EZH2 and repressing p21 in human non-small cell lung cancer.
Intermittent hypoxia mediated by TSP1 dependent on STAT3 induces cardiac fibroblast activation and cardiac fibrosis.
Targeting 7-Dehydrocholesterol Reductase Integrates Cholesterol Metabolism and IRF3 Activation to Eliminate Infection.
Impact of GFRA1 gene reactivation by DNA demethylation on prognosis of patients with metastatic colon cancer.
Synaptic density marker SV2A is reduced in schizophrenia patients and unaffected by antipsychotics in rats.
FHL3 promotes pancreatic cancer invasion and metastasis through preventing the ubiquitination degradation of EMT associated transcription factors.
Endogenous production of C-C motif chemokine ligand 2 by nasopharyngeal carcinoma cells drives radioresistance-associated metastasis.
Yap/Taz are required for establishing the cerebellar radial glia scaffold and proper foliation.
Endothelial microvesicles induced by physiological cyclic stretch inhibit ICAM1-Dependent leukocyte adhesion.
miR-181b-5p inhibits endothelial-mesenchymal transition in monocrotaline-induced pulmonary arterial hypertension by targeting endocan and TGFBR1.
Hepatitis B virus-triggered PTEN/β-catenin/c-Myc signaling enhances PD-L1 expression to promote immune evasion.
Role of the autotaxin-lysophosphatidic acid axis in glaucoma, aqueous humor drainage and fibrogenic activity.
Attenuation of secondary damage and Aβ deposits in the ipsilateral thalamus of dMCAO rats through reduction of cathepsin B by bis(propyl)-cognitin, a multifunctional dimer.
Decreased DHRS2 expression is associated with HDACi resistance and poor prognosis in ovarian cancer.
Identification of chemoresistance-related mRNAs based on gemcitabine-resistant pancreatic cancer cell lines.
Interferon gamma inhibits CXCL8-CXCR2 axis mediated tumor-associated macrophages tumor trafficking and enhances anti-PD1 efficacy in pancreatic cancer.
The key role of macrophage depolarization in the treatment of COPD with ergosterol both in vitro and in vivo.
LL-37 restored glucocorticoid sensitivity impaired by virus dsRNA in lung.
Icariside II improves myocardial fibrosis in spontaneously hypertensive rats by inhibiting collagen synthesis.
Activation of CRHR1 contributes to cerebral endothelial barrier impairment via cPLA2 phosphorylation in experimental ischemic stroke.
Alveolar Stretch Activation of Endothelial Piezo1 Protects Adherens Junctions and Lung Vascular Barrier.
Long non‑coding RNA CASC2 suppresses pancreatic cancer cell growth and progression by regulating the miR‑24/MUC6 axis.
Epiregulin promotes trophoblast epithelial-mesenchymal transition through poFUT1 and O-fucosylation by poFUT1 on uPA.
Long noncoding RNA NEAT1 is involved in the protective effect of Klotho on renal tubular epithelial cells in diabetic kidney disease through the ERK1/2 signaling pathway.
miR-1294 alleviates epithelial-mesenchymal transition by repressing FOXK1 in gastric cancer.
EPHA2 feedback activation limits the response to PDEδ inhibition in KRAS-dependent cancer cells.
A lncRNA coordinates with Ezh2 to inhibit HIF-1α transcription and suppress cancer cell adaption to hypoxia.
RBBP8/CtIP suppresses P21 expression by interacting with CtBP and BRCA1 in gastric cancer.
Comparative Transcriptome Analysis Reveals Different Host Cell Responses to Acute and Persistent Foot-and-Mouth Disease Virus Infection.
Histone deacetylase 6 inhibition restores autophagic flux to promote functional recovery after spinal cord injury.
Bisphenol A Exposure Enhances Endometrial Stromal Cell Invasion and Has a Positive Association with Peritoneal Endometriosis.
HSF1 promotes the viability of islet β-cells via upregulating SIRPα expression.
N-glycosylation of uterine endometrium determines its receptivity.
Protocatechuic Aldehyde Represses Proliferation and Migration of Breast Cancer Cells through Targeting C-terminal Binding Protein 1.
Chidamide induces necroptosis via regulation of c‑FLIPL expression in Jurkat and HUT‑78 cells.
miR‑337‑3p inhibits gastric tumor metastasis by targeting ARHGAP10.
HDAC11 promotes meiotic apparatus assembly during mouse oocyte maturation via decreasing H4K16 and α-tubulin acetylation.
α-synuclein promotes progression of Parkinson's disease by upregulating autophagy signaling pathway to activate NLRP3 inflammasome.
BMP4 induces asymmetric cell division in human glioma stem-like cells.
Maternal exposure to fine particle matters cause autophagy via UPR-mediated PI3K-mTOR pathway in testicular tissue of adult male mice in offspring.
Capping Protein Regulator and Myosin 1 Linker 3 Is Required for Tumor Metastasis.
3-Mercaptopyruvate sulfurtransferase supports endothelial cell angiogenesis and bioenergetics.
Retinoic acid receptor gamma is targeted by microRNA-124 and inhibits neurite outgrowth.
Proteomics profiling of epithelium-derived exosomes from nasal polyps revealed signaling functions affecting cellular proliferation.
Arfgef1 haploinsufficiency in mice alters neuronal endosome composition and decreases membrane surface postsynaptic GABAA receptors.
The role of invariant natural killer T cells in experimental xenobiotic-induced cholestatic hepatotoxicity.
lncRNA SNHG3 facilitates acute myeloid leukemia cell growth via the regulation of miR-758-3p/SRGN axis.
A risk prediction model of DNA methylation improves prognosis evaluation and indicates gene targets in prostate cancer.
Ubiquitination of NOTCH2 by DTX3 suppresses the proliferation and migration of human esophageal carcinoma.
3-O-Acetyl-11-keto- β -boswellic acid ameliorated aberrant metabolic landscape and inhibited autophagy in glioblastoma.
FAM172A inhibits EMT in pancreatic cancer via ERK-MAPK signaling.
Systematic Comparison of Label-Free, SILAC, and TMT Techniques to Study Early Adaption toward Inhibition of EGFR Signaling in the Colorectal Cancer Cell Line DiFi.
Extracellular nanofiber-orchestrated cytoskeletal reorganization and mediated directional migration of cancer cells.
DGCR8/ZFAT-AS1 Promotes CDX2 Transcription in a PRC2 Complex-Dependent Manner to Facilitate the Malignant Biological Behavior of Glioma Cells.
The Fluoro-Thiazolylhydrazone Compound TSC-3C Inhibits Triple Negative Breast Cancer (TNBC) Cell Line Activity by Promoting Apoptosis, Regulating the MAPK Pathway and Inducing Mitochondrial Dysfunction.
Protective properties of heme oxygenase-1 expressed in umbilical cord mesenchymal stem cells help restore the ovarian function of premature ovarian failure mice through activating the JNK/Bcl-2 signal pathway-regulated autophagy and upregulating the circulating of CD8+CD28- T cells.
A DNAH17 missense variant causes flagella destabilization and asthenozoospermia.
Mevalonate metabolism-dependent protein geranylgeranylation regulates thymocyte egress.
Differential effects of Chinese high-fat dietary habits on lipid metabolism: mechanisms and health implications.
Downregulation of lung miR-203a-3p expression by high-altitude hypoxia enhances VEGF/Notch signaling.
SOX2 Represses Hepatitis B Virus Replication by Binding to the Viral EnhII/Cp and Inhibiting the Promoter Activation.
FKBP9 promotes the malignant behavior of glioblastoma cells and confers resistance to endoplasmic reticulum stress inducers.
Assessment of Prolonged Dengue Virus Infection in Dermal Fibroblasts and Hair-Follicle Dermal Papilla Cells.
Anti-inflammatory effects of Lactobacillus johnsonii L531 in a pig model of Salmonella Infantis infection involves modulation of CCR6+ T cell responses and ER stress.
The behavioural and neuropathologic sexual dimorphism and absence of MIP-3α in tau P301S mouse model of Alzheimer's disease.
Rumen-Protected Glucose Stimulates the Insulin-Like Growth Factor System and mTOR/AKT Pathway in the Endometrium of Early Postpartum Dairy Cows.
Structural Basis for Inhibiting Porcine Epidemic Diarrhea Virus Replication with the 3C-Like Protease Inhibitor GC376.
Modulation of in vitro Brain Endothelium by Mechanical Trauma: Structural and Functional Restoration by Poloxamer 188.
A Novel Role for PX, a Structural Protein of Fowl Adenovirus Serotype 4 (FAdV4), as an Apoptosis-Inducer in Leghorn Male Hepatocellular Cell.
Targeted overexpression of the long noncoding RNA ODSM can regulate osteoblast function in vitro and in vivo.
Generation of a self-cleaved inducible Cre recombinase for efficient temporal genetic manipulation.
Overcoming cisplatin resistance by targeting the MTDH-PTEN interaction in ovarian cancer with sera derived from rats exposed to Guizhi Fuling wan extract.
Dynasore potentiates c-Met inhibitors against hepatocellular carcinoma through destabilizing c-Met.
GRWD1 promotes cell proliferation and migration in non-small cell lung cancer by activating the Notch pathway.
Extracellular vesicles transmitted miR-31-5p promotes sorafenib resistance by targeting MLH1 in renal cell carcinoma.
Down-regulation of CCR7 via AKT pathway and GATA2 inactivation suppressed trophoblast migration and invasion in recurrent spontaneous abortion†.
Entorhinal cortex-based metabolic profiling of chronic restraint stress mice model of depression.
Level of N6-Methyladenosine in Peripheral Blood RNA: A Novel Predictive Biomarker for Gastric Cancer.
Sodium butyrate causes α-synuclein degradation by an Atg5-dependent and PI3K/Akt/mTOR-related autophagy pathway.
Nucleostemin promotes hepatocellular carcinoma by regulating the function of STAT3.
Silencing of DsbA-L gene impairs the PPARγ agonist function of improving insulin resistance in a high-glucose cell model.
Autotaxin stimulates LPA2 receptor in macrophages and exacerbates dextran sulfate sodium-induced acute colitis.
Neuron-derived factors negatively modulate ryanodine receptor-mediated calcium release in cultured mouse astrocytes.
Inhibition of PI3K/Akt/NF-κB signaling by Aloin for ameliorating the progression of osteoarthritis: In vitro and in vivo studies.
Protective effect of taraxasterol on ischemia/reperfusion-induced acute kidney injury via inhibition of oxidative stress, inflammation, and apoptosis.
Inhibition of PCSK9 potentiates immune checkpoint therapy for cancer.
Structure of LRRK2 in Parkinson's disease and model for microtubule interaction.
Hepatoprotective effects of Camellia nitidissima aqueous ethanol extract against CCl4-induced acute liver injury in SD rats related to Nrf2 and NF-κB signalling.
Hepatoprotective effect of Xiayuxue decoction ethyl acetate fraction against carbon tetrachloride-induced liver fibrosis in mice via inducing apoptosis and suppressing activation of hepatic stellate cells.
Hypermethylation-mediated silencing of NDRG4 promotes pancreatic ductal adenocarcinoma by regulating mitochondrial function.
Anti-tumour activity of zinc ionophore pyrithione in human ovarian cancer cells through inhibition of proliferation and migration and promotion of lysosome-mitochondrial apoptosis.
Circ_0079593 facilitates proliferation, metastasis, glucose metabolism and inhibits apoptosis in melanoma by regulating the miR-516b/GRM3 axis.
Modulation of miRNAs by vitamin C in H2O2‑exposed human umbilical vein endothelial cells.
The protective effects of umbilical cord-derived endothelial colony forming cells on hepatic veno-occlusive disease.
Tumor cell-expressed IL-15Rα drives antagonistic effects on the progression and immune control of gastric cancer and is epigenetically regulated in EBV-positive gastric cancer.
Aberrant expression of miRNA-192-5p contributes to N,N-dimethylformamide-induced hepatic apoptosis.
Upregulated miR-101 inhibits acute kidney injury-chronic kidney disease transition by regulating epithelial-mesenchymal transition.
The kinesin motor protein KIF4A as a potential therapeutic target in renal cell carcinoma.
Promotion of esophageal adenocarcinoma metastasis via Wnt/ß-catenin signal pathway by sorting nexins 3.
Chondroitin synthase-3 regulates nucleus pulposus degeneration through actin-induced YAP signaling.
Polyphyllin I attenuates cognitive impairments and reduces AD-like pathology through CIP2A-PP2A signaling pathway in 3XTg-AD mice.
Cold-induced RNA-binding protein (CIRBP) regulates the expression of Src-associated during mitosis of 68 kDa (Sam68) and extracellular signal-regulated kinases (ERK) during heat stress-induced testicular injury.
JMY expression by Sertoli cells contributes to mediating spermatogenesis in mice.
Platelet-derived microvesicles promote endothelial progenitor cell proliferation in intimal injury by delivering TGF-β1.
Maresin1 Promotes M2 Macrophage Polarization Through Peroxisome Proliferator-Activated Receptor-γ Activation to Expedite Resolution of Acute Lung Injury.
Inhibition of porcine reproductive and respiratory syndrome virus by PKC inhibitor dequalinium chloride in vitro.
Long noncoding RNA XIST regulates cardiomyocyte apoptosis by targeting miR-873-5p/MCL1 axis.
IGFBP6 regulates vascular smooth muscle cell proliferation and morphology via cyclin E-CDK2.
The proinflammatory cytokines IL-1β and TNF-α modulate corneal epithelial wound healing through p16Ink4a suppressing STAT3 activity.
Sulforaphane suppresses polyinosinic‑polycytidylic acid‑stimulated release of cytokines, chemokines and MMPs by human corneal fibroblasts.
miR‑124‑3p regulates angiogenesis in peripheral arterial disease by targeting STAT3.
Demethylation of HACE1 gene promoter by propofol promotes autophagy of human A549 cells.
Long noncoding RNA HAND2-AS1 reduced the viability of hepatocellular carcinoma via targeting microRNA-300/SOCS5 axis.
UBR5 over-expression contributes to poor prognosis and tamoxifen resistance of ERa+ breast cancer by stabilizing β-catenin.
Loss of hepatic aldolase B activates Akt and promotes hepatocellular carcinogenesis by destabilizing the Aldob/Akt/PP2A protein complex.
A spirostanol saponin isolated from Tupistra chinensis Baker simultaneously induces apoptosis and autophagy by regulating the JNK pathway in human gastric cancer cells.
LGR4 maintains HGSOC cell epithelial phenotype and stem-like traits.
Pentraxin 3 contributes to neurogenesis after traumatic brain injury in mice.
Glycogen synthase kinase-3β inhibition alleviates activation of the NLRP3 inflammasome in myocardial infarction.
The role of invariant natural killer T cells and associated immunoregulatory factors in triptolide-induced cholestatic liver injury.
LINC00673 exerts oncogenic function in cervical cancer by negatively regulating miR-126-5p expression and activates PTEN/PI3K/AKT signaling pathway.
Gu-Ben-Fang-Xiao attenuates allergic airway inflammation by inhibiting BAFF-mediated B cell activation.
Down-regulation of long noncoding RNA LINC00472 alleviates sepsis-induced acute hepatic injury by regulating miR-373-3p/TRIM8 axis.
Enterovirus 71 induces neural cell apoptosis and autophagy through promoting ACOX1 downregulation and ROS generation.
Down-regulation of lncRNA DNAJC3-AS1 inhibits colon cancer via regulating miR-214-3p/LIVIN axis.
Upregulation of the microRNA rno-miR-146b-5p may be involved in the development of intestinal injury through inhibition of Kruppel-like factor 4 in intestinal sepsis.
Cannabinoid receptor subtype influence on neuritogenesis in human SH-SY5Y cells.
Targeted degradation of CD147 proteins in melanoma.
Design, synthesis and biological evaluation of novel 1,3,4-thiadiazole derivatives as anti-glioblastoma agents targeting the AKT pathway.
Latcripin-7A, derivative of Lentinula edodes C91-3, reduces migration and induces apoptosis, autophagy, and cell cycle arrest at G1 phase in breast cancer cells.
Structural and Functional Characterization of Host FHL1 Protein Interaction with Hypervariable Domain of Chikungunya Virus nsP3 Protein.
β-Elemene enhances radiosensitivity in non-small-cell lung cancer by inhibiting epithelial-mesenchymal transition and cancer stem cell traits via Prx-1/NF-kB/iNOS signaling pathway.
Drug-repositioning screening identified fludarabine and risedronic acid as potential therapeutic compounds for malignant pleural mesothelioma.
FN-EDA mediates angiogenesis of hepatic fibrosis via integrin-VEGFR2 in a CD63 synergetic manner.
Dually regulating the proliferation and the immune microenvironment of melanoma via nanoparticle-delivered siRNA targeting onco-immunologic CD155.
Extracellular Cystatin F Is Internalised by Cytotoxic T Lymphocytes and Decreases Their Cytotoxicity.
The protective effect of 1,25(OH)2D3 against cardiac hypertrophy is mediated by the cyclin-dependent kinase inhibitor p21.
YTHDF1 Facilitates the Progression of Hepatocellular Carcinoma by Promoting FZD5 mRNA Translation in an m6A-Dependent Manner.
circFN1 Mediates Sorafenib Resistance of Hepatocellular Carcinoma Cells by Sponging miR-1205 and Regulating E2F1 Expression.
Translatome and Transcriptome Profiling of Hypoxic-Induced Rat Cardiomyocytes.
SPOCK1/SIX1axis promotes breast cancer progression by activating AKT/mTOR signaling.
Exogenous hydrogen sulfide inhibits apoptosis by regulating endoplasmic reticulum stress-autophagy axis and improves myocardial reconstruction after acute myocardial infarction.
Overexpression of Mucin 1 Suppresses the Therapeutical Efficacy of Disulfiram against Canine Mammary Tumor.
Discovery and Biological Evaluation of CD147 N-Glycan Inhibitors: A New Direction in the Treatment of Tumor Metastasis.
Radiosensitization Effect of AGuIX, a Gadolinium-Based Nanoparticle, in Nonsmall Cell Lung Cancer.
Lanthanum chloride causes blood-brain barrier disruption through intracellular calcium-mediated RhoA/Rho kinase signaling and myosin light chain kinase.
Schistosoma mansoni eggs induce Wnt/β-catenin signaling and activate the protooncogene c-Jun in human and hamster colon.
CircPlekha7 plays an anti-fibrotic role in intrauterine adhesions by modulating endometrial stromal cell proliferation and apoptosis.
Rapalink-1 Targets Glioblastoma Stem Cells and Acts Synergistically with Tumor Treating Fields to Reduce Resistance against Temozolomide.
MELK is an oncogenic kinase essential for metastasis, mitotic progression, and programmed death in lung carcinoma.
LncRNA LINC00998 inhibits the malignant glioma phenotype via the CBX3-mediated c-Met/Akt/mTOR axis.
Variants in RABL2A causing male infertility and ciliopathy.
Aldehyde dehydrogenase 2 protects against sympathetic excitation-induced cardiac fibrosis.
Pharmacological activation of the p53 pathway by a new compound CYZ2017 exerts anti-tumor effects.
The deubiquitinase USP36 Regulates DNA replication stress and confers therapeutic resistance through PrimPol stabilization.
S119N Mutation of the E3 Ubiquitin Ligase SPOP Suppresses SLC7A1 Degradation to Regulate Hepatoblastoma Progression.
A novel function of African Swine Fever Virus pE66L in inhibition of host translation by the PKR/eIF2α pathway.
Exosome-mediated Hic-5 regulates proliferation and apoptosis of osteosarcoma via Wnt/β-catenin signal pathway.
Hugan Qingzhi medication ameliorates free fatty acid-induced L02 hepatocyte endoplasmic reticulum stress by regulating the activation of PKC-δ.
Epigenetic Inactivation of α-Internexin Accelerates Microtubule Polymerization in Colorectal Cancer.
Microtubule poleward flux in human cells is driven by the coordinated action of four kinesins.
FGF signaling regulates development by processes beyond canonical pathways.
Silencing of the lncRNA TUG1 attenuates the epithelial-mesenchymal transition of renal tubular epithelial cells by sponging miR-141-3p via regulating β-catenin.
iTRAQ-based proteomics implies inflammasome pathway activation in the prefrontal cortex of CSDS mice may influence resilience and susceptibility.
LncRNA Gm16410 regulates PM2.5-induced lung Endothelial-Mesenchymal Transition via the TGF-β1/Smad3/p-Smad3 pathway.
Inhibition of autophagy enhances cadmium-induced apoptosis in duck renal tubular epithelial cells.
Cadmium inhibits apoptosis of human esophageal epithelial cells by upregulating CDK6.
E3 ligase FBXW7 restricts M2-like tumor-associated macrophage polarization by targeting c-Myc.
Cigarette smoke extract induces airway epithelial cell death via repressing PRMT6/AKT signaling.
Stachydrine ameliorates the progression of intervertebral disc degeneration via the PI3K/Akt/NF-κB signaling pathway: in vitro and in vivo studies.
The induction and characterization of monoclonal antibodies specific to GP of Ebola virus.
The vulnerability of motor and frontal cortex-dependent behaviors in mice expressing ALS-linked mutation in TDP-43.
Differential Effects of Components in Artemisia annua Extract on the Induction of Drug-Metabolizing Enzyme Expression Mediated by Nuclear Receptors.
Rhein attenuates renal inflammatory injury of uric acid nephropathy via lincRNA-Cox2/miR-150-5p/STAT1 axis.
Melatonin alleviates intestinal injury, neuroinflammation and cognitive dysfunction caused by intestinal ischemia/reperfusion.
IL-38 alleviates the inflammatory response and the degeneration of nucleus pulposus cells via inhibition of the NF-κB signaling pathway in vitro.
To what extent should the intestinal be resected proximally after radiotherapy: hint from a pathological view.
Rationalized inhibition of mixed lineage kinase 3 and CD70 enhances life span and antitumor efficacy of CD8+ T cells.
The role of miR-34c-5p/Notch in epithelial-mesenchymal transition (EMT) in endometriosis.
miR-296-5p suppresses stem cell potency of hepatocellular carcinoma cells via regulating Brg1/Sall4 axis.
m6A mRNA Methylation Controls Functional Maturation in Neonatal Murine β-Cells.
Metabolomic profiling reveals similar cytotoxic effects and protective functions of quercetin during deoxynivalenol- and 15-acetyl deoxynivalenol-induced cell apoptosis.
miR-410-5p promotes the development of diabetic cardiomyopathy by suppressing PIM1-induced anti-apoptosis.
Exosomes derived from human exfoliated deciduous teeth ameliorate adult bone loss in mice through promoting osteogenesis.
The AKR1B1 inhibitor epalrestat suppresses the progression of cervical cancer.
Neferine Inhibits Expression of Inflammatory Mediators and Matrix Degrading Enzymes in IL-1β-Treated Rat Chondrocytes via Suppressing MAPK and NF-κB Signaling Pathways.
Schisandrin B improves cerebral ischemia and reduces reperfusion injury in rats through TLR4/NF-κB signaling pathway inhibition.
Rare mutations in the autophagy-regulating gene AMBRA1 contribute to human neural tube defects.
Red nucleus IL-6 mediates the maintenance of neuropathic pain by inducing the productions of TNF-α and IL-1β through the JAK2/STAT3 and ERK signaling pathways.
Astragaloside IV attenuates chronic intermittent hypoxia-induced myocardial injury by modulating Ca2+ homeostasis.
MiR-129-5p alleviates myocardial injury by targeting suppressor of cytokine signaling 2 after ischemia/reperfusion.
Effect of AmyTrap, an amyloid-β binding drug, on Aβ induced mitochondrial dysfunction and tau phosphorylation in cultured neuroblastoma cells.
Curcumin inhibits calcification of human aortic valve interstitial cells by interfering NF-κB, AKT, and ERK pathways.
Src-mediated phosphorylation of GAPDH regulates its nuclear localization and cellular response to DNA damage.
Hydrogen sulphide ameliorating skeletal muscle atrophy in db/db mice via Muscle RING finger 1 S-sulfhydration.
Effects of PYRIN-containing Apaf1-like protein 1 on isoflurane-induced postoperative cognitive dysfunction in aged rats.
Overexpression of negative regulator of ubiquitin-like proteins 1 (NUB1) inhibits proliferation and invasion of gastric cancer cells through upregulation of p27Kip1 and inhibition of epithelial-mesenchymal transition.
Cloning of the XPD gene and its function in malignant melanoma cells.
miR-140-3p enhances cisplatin sensitivity and attenuates stem cell-like properties through repressing Wnt/β-catenin signaling in lung adenocarcinoma cells.
ZMIZ1 promotes the proliferation and migration of melanocytes in vitiligo.
BX795 demonstrates potent antiviral benefits against herpes simplex Virus-1 infection of human cell lines.
miR-106a Regulates Cell Proliferation and Autophagy by Targeting LKB1 in HPV-16-Associated Cervical Cancer.
Targeting G6PD reverses paclitaxel resistance in ovarian cancer by suppressing GSTP1.
Celastrol ameliorates autoimmune disorders in Trex1-deficient mice.
Hippocampal glutamatergic synapses impairment mediated novel-object recognition dysfunction in rats with neuropathic pain.
Correcting abnormalities in miR-124/PTPN1 signaling rescues tau pathology in Alzheimer's disease.
Overexpression of PTEN regulated by miR-19b and miR-494 in the villous of recurrent spontaneous abortion patients.
Apocynum venetum leaf extract protects against H2O2-induced oxidative stress by increasing autophagy in PC12 cells.
Prunella vulgaris L. attenuates experimental autoimmune thyroiditis by inducing indoleamine 2,3-dioxygenase 1 expression and regulatory T cell expansion.
Glibenclamide restores dopaminergic reward circuitry in obese mice through interscauplar brown adipose tissue.
MiR-195 suppression alleviates apoptosis and oxidative stress in CCl4-induced ALI in mice by targeting Pim-1.
Sarcopenia is attenuated by TRB3 knockout in aging mice via the alleviation of atrophy and fibrosis of skeletal muscles.
The mechanism of Chinese herbal formula HQT in the treatment of rheumatoid arthritis is related to its regulation of lncRNA uc.477 and miR-19b.
MiR-221/222 promote migration and invasion, and inhibit autophagy and apoptosis by modulating ATG10 in aggressive papillary thyroid carcinoma.
METTL3 and N6-Methyladenosine Promote Homologous Recombination-Mediated Repair of DSBs by Modulating DNA-RNA Hybrid Accumulation.
Partial MHC/neuroantigen peptide constructs attenuate methamphetamine-seeking and brain chemokine (C-C motif) ligand 2 levels in rats.
Schisandrin ameliorates cognitive deficits, endoplasmic reticulum stress and neuroinflammation in streptozotocin (STZ)-induced Alzheimer's disease rats.
Butyrate-mediated autophagy inhibition limits cytosolic Salmonella Infantis replication in the colon of pigs treated with a mixture of Lactobacillus and Bacillus.
Neutrophil extracellular traps amplify neutrophil recruitment and inflammation in neutrophilic asthma by stimulating the airway epithelial cells to activate the TLR4/ NF-κB pathway and secrete chemokines.
DNA methylation of Hugl-2 is a prognostic biomarker in kidney renal clear cell carcinoma.
Icotinib Attenuates Monocrotaline-Induced Pulmonary Hypertension by Preventing Pulmonary Arterial Smooth Muscle Cell Dysfunction.
Macrophage K63-Linked Ubiquitination of YAP Promotes Its Nuclear Localization and Exacerbates Atherosclerosis.
Nicotinamide Mononucleotide Supplementation Reverses the Declining Quality of Maternally Aged Oocytes.
miR-4634 augments the anti-tumor effects of RAD001 and associates well with clinical prognosis of non-small cell lung cancer.
An Optimized Reverse Genetics System Suitable for Efficient Recovery of Simian, Human, and Murine-Like Rotaviruses.
16-Hydroxycleroda-3,13-dien-15,16-olide Induces Apoptosis in Human Bladder Cancer Cells through Cell Cycle Arrest, Mitochondria ROS Overproduction, and Inactivation of EGFR-Related Signalling Pathways.
Promising xenograft animal model recapitulating the features of human pancreatic cancer.
LncRNA SNHG16 promotes colorectal cancer cell proliferation, migration, and epithelial-mesenchymal transition through miR-124-3p/MCP-1.
The HMGB1-2 Ovarian Cancer Interactome. The Role of HMGB Proteins and Their Interacting Partners MIEN1 and NOP53 in Ovary Cancer and Drug-Response.
Chidamide, a histone deacetylase inhibitor, inhibits autophagy and exhibits therapeutic implication in chronic lymphocytic leukemia.
The Circadian Hormone Melatonin Inhibits Morphine-Induced Tolerance and Inflammation via the Activation of Antioxidative Enzymes.
Small molecules targeting RORγt inhibit autoimmune disease by suppressing Th17 cell differentiation.
The gut microbiota regulates autism-like behavior by mediating vitamin B6 homeostasis in EphB6-deficient mice.
In Vitro and In Vivo Activity, Tolerability, and Mechanism of Action of BX795 as an Antiviral against Herpes Simplex Virus 2 Genital Infection.
A kinase-independent function for AURORA-A in replisome assembly during DNA replication initiation.
A CRISPR knockout negative screen reveals synergy between CDKs inhibitor and metformin in the treatment of human cancer in vitro and in vivo.
Exosomal Delivery of AntagomiRs Targeting Viral and Cellular MicroRNAs Synergistically Inhibits Cancer Angiogenesis.
Antidepressant-like Effect of Merazin Hydrate Depends on NO/ERK by Suppressing Its Downstream NF-κB or Nonactivating CREB/BDNF in Mouse Hippocampus.
Ubiquitin-Conjugating Enzyme 2S Enhances Viral Replication by Inhibiting Type I IFN Production through Recruiting USP15 to Deubiquitinate TBK1.
Novel dot-blot assay for detection of vascular Notch3 aggregates in patients with CADASIL.
Lamin B2 promotes the malignant phenotype of non-small cell lung cancer cells by upregulating dimethylation of histone 3 lysine 9.
Lactobacillus johnsonii L531 Ameliorates Escherichia coli-Induced Cell Damage via Inhibiting NLRP3 Inflammasome Activity and Promoting ATG5/ATG16L1-Mediated Autophagy in Porcine Mammary Epithelial Cells.
Magnetic targeting enhances the cutaneous wound healing effects of human mesenchymal stem cell-derived iron oxide exosomes.
TRIM59 attenuates IL-1β-driven cartilage matrix degradation in osteoarthritis via direct suppression of NF-κB and JAK2/STAT3 signaling pathway.
A cell-based high-throughput screen identifies drugs that cause bleeding disorders by off-targeting the vitamin K cycle.
Flavagline synthetic derivative induces senescence in glioblastoma cancer cells without being toxic to healthy astrocytes.
Acetylation of Cytidine Residues Boosts HIV-1 Gene Expression by Increasing Viral RNA Stability.
Amyloid precursor protein glycosylation is altered in the brain of patients with Alzheimer's disease.
Expressional Localization and Functionally Identifying an RNA Editing Enzyme BmADARa of the Silkworm Bombyx mori.
Qingda granule inhibits angiotensin Ⅱ induced VSMCs proliferation through MAPK and PI3K/AKT pathways.
Frequent and mild scrotal heat stress in mice epigenetically alters glucose metabolism in the male offspring.
Dual-specificity phosphatase 29 is induced during neurogenic skeletal muscle atrophy and attenuates glucocorticoid receptor activity in muscle cell culture.
Chlorogenic acid attenuates cyclophosphamide-induced rat interstitial cystitis.
Syndecan-1 regulates extracellular matrix expression in keloid fibroblasts via TGF-β1/Smad and MAPK signaling pathways.
Dandelion Extract Alleviated Lipopolysaccharide-Induced Oxidative Stress through the Nrf2 Pathway in Bovine Mammary Epithelial Cells.
MicroRNA-378-3p/5p suppresses the migration and invasiveness of oral squamous carcinoma cells by inhibiting KLK4 expression.
Anethole compromises human sperm function by affecting the sperm intracellular calcium concentration and tyrosine phosphorylation.
miR-455-3p enhances chondrocytes apoptosis and inflammation by targeting COL2A1 in the in vitro osteoarthritis model.
Glaucocalyxin A alleviates LPS-mediated septic shock and inflammation via inhibiting NLRP3 inflammasome activation.
Baicalin attenuates hepatic injury in non-alcoholic steatohepatitis cell model by suppressing inflammasome-dependent GSDMD-mediated cell pyroptosis.
Cellular secretion and cytotoxicity of transthyretin mutant proteins underlie late-onset amyloidosis and neurodegeneration.
Synergistic effects of tanshinone IIA and andrographolide on the apoptosis of cancer cells via crosstalk between p53 and reactive oxygen species pathways.
Streptococcus pneumoniae aminopeptidase N contributes to bacterial virulence and elicits a strong innate immune response through MAPK and PI3K/AKT signaling.
E6‑regulated overproduction of prostaglandin E2 may inhibit migration of dendritic cells in human papillomavirus 16‑positive cervical lesions.
Effects of rutin on the oxidative stress, proliferation and osteogenic differentiation of periodontal ligament stem cells in LPS-induced inflammatory environment and the underlying mechanism.
Long noncoding RNA MACC1-AS1 promotes the stemness of hepatocellular carcinoma cells by antagonizing miR-145.
LncRNA MIAT/miR-133a-3p axis regulates atrial fibrillation and atrial fibrillation-induced myocardial fibrosis.
Low-intensity pulsed ultrasound promotes the expression of immediate-early genes in mouse ST2 bone marrow stromal cells.
Down-regulation of lncRNA BLACAT1 inhibits ovarian cancer progression by suppressing the Wnt/β-catenin signaling pathway via regulating miR-519d-3p.
Rab22a is a novel prognostic marker for cell progression in breast cancer.
Sirtuin 2 Inhibition Attenuates Sevoflurane-Induced Learning and Memory Deficits in Developing Rats via Modulating Microglial Activation.
CFIm25-regulated lncRNA acv3UTR promotes gastric tumorigenesis via miR-590-5p/YAP1 axis.
MiR-194-5p inhibited metastasis and EMT of nephroblastoma cells through targeting Crk.
MTH1 Inhibitor TH287 Suppresses Gastric Cancer Development Through the Regulation of PI3K/AKT Signaling.
Regulation of hepatic glutamine metabolism by miR-122.
Different Serotypes of Adeno-Associated Virus Vector- and Lentivirus-Mediated Tropism in Choroid Plexus by Intracerebroventricular Delivery.
Nicotinamide riboside rescues angiotensin II-induced cerebral small vessel disease in mice.
Estrogen accelerates heart regeneration by promoting the inflammatory response in zebrafish.
Potent USP10/13 antagonist spautin-1 suppresses melanoma growth via ROS-mediated DNA damage and exhibits synergy with cisplatin.
METTL3/YTHDF2 m6 A axis promotes tumorigenesis by degrading SETD7 and KLF4 mRNAs in bladder cancer.
MiR-210-3p-EphrinA3-PI3K/AKT axis regulates the progression of oral cancer.
Long noncoding RNA FBXL19-AS1 induces tumor growth and metastasis by sponging miR-203a-3p in lung adenocarcinoma.
Estradiol-17β regulates proliferation and apoptosis of sheep endometrial epithelial cells by regulating the relative abundance of YAP1.
Long non‑coding RNA MALAT1 regulates cholesterol accumulation in ox‑LDL‑induced macrophages via the microRNA‑17‑5p/ABCA1 axis.
C9orf72 associates with inactive Rag GTPases and regulates mTORC1-mediated autophagosomal and lysosomal biogenesis.
Effects of propofol on LC3II and mTOR/p-mTOR expression during ischemia-reperfusion myocardium injury in rats with type 2 diabetes mellitus.
Galantamine Inhibits Aβ1-42-Induced Neurotoxicity by Enhancing α7nAChR Expression as a Cargo Carrier for LC3 Binding and Aβ1-42 Engulfment During Autophagic Degradation.
Ehrlichia chaffeensis TRP120-mediated ubiquitination and proteasomal degradation of tumor suppressor FBW7 increases oncoprotein stability and promotes infection.
Potential role of full-length and nonfull-length progranulin in affecting aortic valve calcification.
Overcoming acquired resistance of EGFR-mutant NSCLC cells to the third generation EGFR inhibitor, osimertinib, with the natural product honokiol.
3,4,5-Tri-O-caffeoylquinic acid methyl ester isolated from Lonicera japonica Thunb. Flower buds facilitates hepatitis B virus replication in HepG2.2.15 cells.
Photobiomodulation by diffusing optical fiber on spinal cord: A feasibility study in piglet model.
Tissue Transglutaminase contributes to myelin phagocytosis in interleukin-4-treated human monocyte-derived macrophages.
Prazosin inhibits the proliferation and survival of acute myeloid leukaemia cells through down-regulating TNS1.
Circ-IGF1R inhibits cell invasion and migration in non-small cell lung cancer.
Low-dose lithium feeding increases the SERCA2a-to-phospholamban ratio, improving SERCA function in murine left ventricles.
Dexmedetomidine alleviates postoperative cognitive dysfunction through circular RNA in aged rats.
Small Nucleolar RNA, C/D Box 16 (SNORD16) Acts as a Potential Prognostic Biomarker in Colon Cancer.
PGN and LTA from Staphylococcus aureus Induced Inflammation and Decreased Lactation through Regulating DNA Methylation and Histone H3 Acetylation in Bovine Mammary Epithelial Cells.
Caspase-8 Induces Lysosome-Associated Cell Death in Cancer Cells.
Type 3 adenylyl cyclase in the MOE is involved in learning and memory in mice.
α-Tubulin detyrosination impairs mitotic error correction by suppressing MCAK centromeric activity.
Impaired autophagic flux contributes to muscle atrophy in obesity by affecting muscle degradation and regeneration.
The cellular expression and proteolytic processing of the amyloid precursor protein is independent of TDP-43.
METTL3 is essential for postnatal development of brown adipose tissue and energy expenditure in mice.
Breast cancer-derived exosomes transmit lncRNA SNHG16 to induce CD73+γδ1 Treg cells.
Dimethyl itaconate, an itaconate derivative, exhibits immunomodulatory effects on neuroinflammation in experimental autoimmune encephalomyelitis.
ACE2 correlated with immune infiltration serves as a prognostic biomarker in endometrial carcinoma and renal papillary cell carcinoma: implication for COVID-19.
PENK inhibits osteosarcoma cell migration by activating the PI3K/Akt signaling pathway.
Inhibition of cGAS-Mediated Interferon Response Facilitates Transgene Expression.
4,5-di-O-caffeoylquinic acid methyl ester isolated from Lonicera japonica Thunb. targets the Keap1/Nrf2 pathway to attenuate H2O2-induced liver oxidative damage in HepG2 cells.
Pathogenic Variants in CEP85L Cause Sporadic and Familial Posterior Predominant Lissencephaly.
The potential role of Krüppel-like factor 13 (Aj-klf13) in the intestine regeneration of sea cucumber Apostichopus japonicus.
Carnosol inhibits inflammasome activation by directly targeting HSP90 to treat inflammasome-mediated diseases.
Sitagliptin Inhibits Extracellular Matrix Accumulation and Proliferation in Lung Fibroblasts.
Alamandine attenuates hepatic fibrosis by regulating autophagy induced by NOX4-dependent ROS.
Reverse Genetics Reveals a Role of Rotavirus VP3 Phosphodiesterase Activity in Inhibiting RNase L Signaling and Contributing to Intestinal Viral Replication In Vivo.
Induced CD10 expression during monocyte-to-macrophage differentiation identifies a unique subset of macrophages in pancreatic ductal adenocarcinoma.
Zhx2 Accelerates Sepsis by Promoting Macrophage Glycolysis via Pfkfb3.
NOD1 Promotes Antiviral Signaling by Binding Viral RNA and Regulating the Interaction of MDA5 and MAVS.
The circular RNA CDR1as regulate cell proliferation via TMED2 and TMED10.
Betulinic Acid-Mediated Tuning of PERK/CHOP Signaling by Sp1 Inhibition as a Novel Therapeutic Strategy for Glioblastoma.
Interleukin 26 Skews Macrophage Polarization Towards M1 Phenotype by Activating cJUN and the NF-κB Pathway.
Doxorubicin-polyglycerol-nanodiamond conjugates disrupt STAT3/IL-6-mediated reciprocal activation loop between glioblastoma cells and astrocytes.
A Novel Rhynchophylline Analog, Y396, Inhibits Endothelial Dysfunction Induced by Oxidative Stress in Diabetes Through Epidermal Growth Factor Receptor.
The HIV-1 capsid-binding host factor CPSF6 is post-transcriptionally regulated by the cellular microRNA miR-125b.
Paraoxonase 3 functions as a chaperone to decrease functional expression of the epithelial sodium channel.
FTO promotes cell proliferation and migration in esophageal squamous cell carcinoma through up-regulation of MMP13.
Adipose-derived exosomes protect the pulmonary endothelial barrier in ventilator-induced lung injury by inhibiting the TRPV4/Ca2+ signaling pathway.
miR-524-5p inhibits angiogenesis through targeting WNK1 in colon cancer cells.
OTUD1 Negatively Regulates Type I IFN Induction by Disrupting Noncanonical Ubiquitination of IRF3.
Lanthanum chloride impairs spatial learning and memory by inducing [Ca2+]m overload, mitochondrial fission-fusion disorder and excessive mitophagy in hippocampal nerve cells of rats.
The protective effects of β-sitosterol and vermicularin from Thamnolia vermicularis (Sw.) Ach. against skin aging in vitro.
Tumor-associated macrophages (TAMs) depend on Shp2 for their anti-tumor roles in colorectal cancer.
Progerin accumulation in nucleus pulposus cells impairs mitochondrial function and induces intervertebral disc degeneration and therapeutic effects of sulforaphane.
Overexpression of MEF2D contributes to oncogenic malignancy and chemotherapeutic resistance in ovarian carcinoma.
Changes in the intestinal microecology induced by bacillus subtilis inhibit the occurrence of ulcerative colitis and associated cancers: a study on the mechanisms.
Collaborative ISL1/GATA3 interaction in controlling neuroblastoma oncogenic pathways overlapping with but distinct from MYCN.
CACYBP Enhances Cytoplasmic Retention of P27Kip1 to Promote Hepatocellular Carcinoma Progression in the Absence of RNF41 Mediated Degradation.
Inhibition of SMYD2 suppresses tumor progression by down-regulating microRNA-125b and attenuates multi-drug resistance in renal cell carcinoma.
A Compound AC1Q3QWB Selectively Disrupts HOTAIR-Mediated Recruitment of PRC2 and Enhances Cancer Therapy of DZNep.
Autophagy impairment contributes to PBDE-47-induced developmental neurotoxicity and its relationship with apoptosis.
Long noncoding RNA GAS5 inhibits metastasis by targeting miR-182/ANGPTL1 in hepatocellular carcinoma.
CRISPRa-mediated FOXP3 gene upregulation in mammalian cells.
Aurora-A Induces Chemoresistance Through Activation of the AKT/mTOR Pathway in Endometrial Cancer.
Antitumor Effects of Berberine on Gliomas via Inactivation of Caspase-1-Mediated IL-1β and IL-18 Release.
A Novel Citrullinated Modification of Histone 3 and Its Regulatory Mechanisms Related to IPO-38 Antibody-Labeled Protein.
Nociceptin Receptor Is Overexpressed in Non-small Cell Lung Cancer and Predicts Poor Prognosis.
Identification of a Two-Gene (PML-EPB41) Signature With Independent Prognostic Value in Osteosarcoma.
PA28α/β Promote Breast Cancer Cell Invasion and Metastasis via Down-Regulation of CDK15.
Long Non-coding RNA SNHG12 Functions as a Competing Endogenous RNA to Regulate MDM4 Expression by Sponging miR-129-5p in Clear Cell Renal Cell Carcinoma.
The Tumor Suppressor Role of Zinc Finger Protein 671 (ZNF671) in Multiple Tumors Based on Cancer Single-Cell Sequencing.
MRPS30-DT Knockdown Inhibits Breast Cancer Progression by Targeting Jab1/Cops5.
FA2H Exhibits Tumor Suppressive Roles on Breast Cancers via Cancer Stemness Control.
SEMA3C Promotes Cervical Cancer Growth and Is Associated With Poor Prognosis.
Heatstroke-induced hepatocyte exosomes promote liver injury by activating the NOD-like receptor signaling pathway in mice.
Structural basis for the recognition of K48-linked Ub chain by proteasomal receptor Rpn13.
Loss of the Golgi Matrix Protein 130 Cause Aberrant IgA1 Glycosylation in IgA Nephropathy.
Hsa_circ_001569 is an unfavorable prognostic factor and promotes cell proliferation and metastasis by modulating PI3K-AKT pathway in breast cancer.
Long noncoding RNA glutathione peroxidase 3-antisense inhibits lens epithelial cell apoptosis by upregulating glutathione peroxidase 3 expression in age-related cataract.
The long noncoding RNA LINC00483 promotes lung adenocarcinoma progression by sponging miR-204-3p.
Effect of MicroRNA-20a on Osteogenic Differentiation of Human Adipose Tissue-Derived Stem Cells.
Xiaokeping Mixture Attenuates Diabetic Kidney Disease by Modulating TGF-β/Smad Pathway in db/db Mice.
Mangiferin Prevents TBHP-Induced Apoptosis and ECM Degradation in Mouse Osteoarthritic Chondrocytes via Restoring Autophagy and Ameliorates Murine Osteoarthritis.
A Peptide Analogue of Selectin Ligands Attenuated Atherosclerosis by Inhibiting Monocyte Activation.
Modulations of Histone Deacetylase 2 Offer a Protective Effect through the Mitochondrial Apoptosis Pathway in Acute Liver Failure.
Therapeutic Effects of Human Urine-Derived Stem Cells in a Rat Model of Cisplatin-Induced Acute Kidney Injury In Vivo and In Vitro.
Targeting INHBA in Ovarian Cancer Cells Suppresses Cancer Xenograft Growth by Attenuating Stromal Fibroblast Activation.
Abnormal Ribosome Biogenesis Partly Induced p53-Dependent Aortic Medial Smooth Muscle Cell Apoptosis and Oxidative Stress.
Pretreatment with AM1241 Enhances the Analgesic Effect of Intrathecally Administrated Mesenchymal Stem Cells.
Effect of YAP on an Immortalized Periodontal Ligament Stem Cell Line.
Bufei Qingyu Granules Inhibit the Development of Systemic Sclerosis via Notch-1/Jagged-2 Signaling Pathway.
Melatonin Rescued Reactive Oxygen Species-Impaired Osteogenesis of Human Bone Marrow Mesenchymal Stem Cells in the Presence of Tumor Necrosis Factor-Alpha.
Hepatitis B Virus X Protein-Induced RORγ Expression to Promote the Migration and Proliferation of Hepatocellular Carcinoma.
Identification of Upregulated HNRNPs Associated with Poor Prognosis in Pancreatic Cancer.
N-Acetylcysteine Attenuates Cisplatin-Induced Acute Kidney Injury by Inhibiting the C5a Receptor.
NANOG Attenuates Hair Follicle-Derived Mesenchymal Stem Cell Senescence by Upregulating PBX1 and Activating AKT Signaling.
Cul4a as a New Interaction Protein of PARP1 Inhibits Oxidative Stress-Induced H9c2 Cell Apoptosis.
Bu Shen Zhu Yun Decoction Improves Endometrial Receptivity via VEGFR-2-Mediated Angiogenesis.
Loss of SDC1 Expression Is Associated with Poor Prognosis of Colorectal Cancer Patients in Northern China.
Genetically Modified Porcine Mesenchymal Stem Cells by Lentiviral Tbx18 Create a Biological Pacemaker.
Protocatechuic Acid-Mediated miR-219a-5p Activation Inhibits the p66shc Oxidant Pathway to Alleviate Alcoholic Liver Injury.
Upregulation of UCP2 Expression Protects against LPS-Induced Oxidative Stress and Apoptosis in Cardiomyocytes.
Identification of CTRP1 as a Prognostic Biomarker and Oncogene in Human Glioblastoma.
A regulatory circuit of circ-MTO1/miR-17/QKI-5 inhibits the proliferation of lung adenocarcinoma.
Long non-coding RNA ARAP1-AS1 promotes the progression of bladder cancer by regulating miR-4735-3p/NOTCH2 axis.
The m6A eraser FTO facilitates proliferation and migration of human cervical cancer cells.
The long noncoding RNA PCGEM1 promotes cell proliferation, migration and invasion via targeting the miR-182/FBXW11 axis in cervical cancer.
LncRNA DANCR promotes the proliferation, migration, and invasion of tongue squamous cell carcinoma cells through miR-135a-5p/KLF8 axis.
Strand-specific miR-28-3p and miR-28-5p have differential effects on nasopharyngeal cancer cells proliferation, apoptosis, migration and invasion.
Methods for Monitoring Autophagy in Silkworm Organs.
MicroRNA-29a is a key regulon that regulates BRD4 and mitigates liver fibrosis in mice by inhibiting hepatic stellate cell activation.
LncRNA SNHG6 promotes proliferation, invasion and migration in colorectal cancer cells by activating TGF-β/Smad signaling pathway via targeting UPF1 and inducing EMT via regulation of ZEB1.
Ccr7 null mice are protected against diet-induced obesity via Ucp1 upregulation and enhanced energy expenditure.
Hypericin maintians PDX1 expression via the Erk pathway and protects islet β-cells against glucotoxicity and lipotoxicity.
KLF4-Mediated CDH3 Upregulation Suppresses Human Hepatoma Cell Growth and Migration via GSK-3β Signaling.
Taurine Transporter Regulates Adipogenic Differentiation of Human Adipose-Derived Stem Cells through Affecting Wnt/β-catenin Signaling Pathway.
Upregulated MMP28 in Hepatocellular Carcinoma Promotes Metastasis via Notch3 Signaling and Predicts Unfavorable Prognosis.
Inhibition of Heme Oxygenase-1 enhances hyperthermia-induced autophagy and antiviral effect.
MiR-93 regulates vascular smooth muscle cell proliferation, and neointimal formation through targeting Mfn2.
Muscle Injury Associated Elevated Oxidative Stress and Abnormal Myogenesis in Patients with Idiopathic Scoliosis.
Resveratrol induced premature senescence and inhibited epithelial-mesenchymal transition of cancer cells via induction of tumor suppressor Rad9.
Progranulin deficiency leads to reduced glucocerebrosidase activity.
Radiotherapy resistance acquisition in Glioblastoma. Role of SOCS1 and SOCS3.
P16 methylation increases the sensitivity of cancer cells to the CDK4/6 inhibitor palbociclib.
Porous Se@SiO2 nanospheres attenuate ischemia/reperfusion (I/R)-induced acute kidney injury (AKI) and inflammation by antioxidative stress.
Long-Term Effects of Zinc Deficiency and Zinc Supplementation on Developmental Seizure-Induced Brain Damage and the Underlying GPR39/ZnT-3 and MBP Expression in the Hippocampus.
Effects of Acupuncture on Behavioral Stereotypies and Brain Dopamine System in Mice as a Model of Tourette Syndrome.
Calsyntenin-1 Negatively Regulates ICAM5 Accumulation in Postsynaptic Membrane and Influences Dendritic Spine Maturation in a Mouse Model of Fragile X Syndrome.
Osteoprotegerin promotes islet β cell proliferation in intrauterine growth retardation rats through the PI3K/AKT/FoxO1 pathway.
CD147 promotes cervical cancer migration and invasion by up-regulating fatty acid synthase expression.
CLK3 Is A Direct Target Of miR-144 And Contributes To Aggressive Progression In Hepatocellular Carcinoma.
Downregulation of CENPK suppresses hepatocellular carcinoma malignant progression through regulating YAP1.
INPP4B As A Prognostic And Diagnostic Marker Regulates Cell Growth Of Pancreatic Cancer Via Activating AKT.
GADD45a Mediated Cell Cycle Inhibition Is Regulated By P53 In Bladder Cancer.
MicroRNA-217 acts as a tumor suppressor and correlates with the chemoresistance of cervical carcinoma to cisplatin.
GJB4 promotes gastric cancer cell proliferation and migration via Wnt/CTNNB1 pathway.
GPX2 suppression of H2O2 stress regulates cervical cancer metastasis and apoptosis via activation of the β-catenin-WNT pathway.
tRNA-derived fragment tRF-03357 promotes cell proliferation, migration and invasion in high-grade serous ovarian cancer.
14-Deoxycoleon U-induced endoplasmic reticulum stress-mediated apoptosis, autophagy, and cell cycle arrest in lung adenocarcinoma.
Diallyl disulfide inhibits colon cancer metastasis by suppressing Rac1-mediated epithelial-mesenchymal transition.
LncRNA FENDRR attenuates colon cancer progression by repression of SOX4 protein.
Exosomal Tenascin-c induces proliferation and invasion of pancreatic cancer cells by WNT signaling.
Silencing UBE4B induces nasopharyngeal carcinoma apoptosis through the activation of caspase3 and p53.
AdipoRon Alleviates Free Fatty Acid-Induced Myocardial Cell Injury Via Suppressing Nlrp3 Inflammasome Activation.
RRAD suppresses the Warburg effect by downregulating ACTG1 in hepatocellular carcinoma.
Upregulation of STC2 in colorectal cancer and its clinicopathological significance.
Oncogenic Role and Prognostic Value of MicroRNA-937-3p in Patients with Breast Cancer.
Osteoglycin (OGN) Inhibits Cell Proliferation and Invasiveness in Breast Cancer via PI3K/Akt/mTOR Signaling Pathway.
Overexpressing CCT6A Contributes To Cancer Cell Growth By Affecting The G1-To-S Phase Transition And Predicts A Negative Prognosis In Hepatocellular Carcinoma.
miR-140-3p Suppresses Cell Growth And Induces Apoptosis In Colorectal Cancer By Targeting PD-L1.
Osteopontin Mediates Cetuximab Resistance via the MAPK Pathway in NSCLC Cells.
Long noncoding RNA CASC15 predicts unfavorable prognosis and exerts oncogenic functions in non-small cell lung cancer.
MiR-27a-regulated FOXO1 promotes pancreatic ductal adenocarcinoma cell progression by enhancing Wnt/β-catenin signaling activity.
Low-molecular-weight fucoidan attenuates bleomycin-induced pulmonary fibrosis: possible role in inhibiting TGF-β1-induced epithelial-mesenchymal transition through ERK pathway.
Vitamin D retards intervertebral disc degeneration through inactivation of the NF-κB pathway in mice.
Herbacetin treatment remitted LPS induced inhibition of osteoblast differentiation through blocking AKT/NF-κB signaling pathway.
BPTF cooperates with p50 NF-κB to promote COX-2 expression and tumor cell growth in lung cancer.
Protective effects of Ulinastatin on oxidative stress and inflammation of rat-derived cardiomyocytes H9c2.
A pilot study comparing the genetic molecular biology of gestational and non-gestational choriocarcinoma.
HnRNP-F promotes cell proliferation by regulating TPX2 in bladder cancer.
UBE2T promotes proliferation via G2/M checkpoint in hepatocellular carcinoma.
Overexpression of HOXC6 promotes cell proliferation and migration via MAPK signaling and predicts a poor prognosis in glioblastoma.
Upregulation of family with sequence similarity 83 member D expression enhances cell proliferation and motility via activation of Wnt/β-catenin signaling and predicts poor prognosis in gastric cancer.
The β-galactoside α2,6-sialyltranferase 1 (ST6GAL1) inhibits the colorectal cancer metastasis by stabilizing intercellular adhesion molecule-1 via sialylation.
siPRDX2-elevated DNM3 inhibits the proliferation and metastasis of colon cancer cells via AKT signaling pathway.
Candidate tumor suppressor gene IRF6 is involved in human breast cancer pathogenesis via modulating PI3K-regulatory subunit PIK3R2 expression.
Dl-3-n-Butylphthalide Exerts Dopaminergic Neuroprotection Through Inhibition of Neuroinflammation.
UNBS5162 and amonafide inhibits tumor progression in human melanoma by the AKT/mTOR pathway.
The oncogenic role of GNL3 in the progression and metastasis of osteosarcoma.
Peptide V3 Inhibits the Growth of Human Hepatocellular Carcinoma by Inhibiting the Ras/Raf/MEK/ERK Signaling Pathway.
Lyn Kinase Promotes the Proliferation of Malignant Melanoma Cells through Inhibition of Apoptosis and Autophagy via the PI3K/Akt Signaling Pathway.
High expression of calreticulin indicates poor prognosis and modulates cell migration and invasion via activating Stat3 in nasopharyngeal carcinoma.
The Role of the Tumor Microenvironment in Neuropilin 1-Induced Radiation Resistance in Lung Cancer Cells.
KIAA0101 is a novel transcriptional target of FoxM1 and is involved in the regulation of hepatocellular carcinoma microvascular invasion by regulating epithelial-mesenchymal transition.
Association of SMUG1 SNPs in Intron Region and Linkage Disequilibrium with Occurrence of Cervical Carcinoma and HPV Infection in Chinese Population.
PINK1/Parkin-Mediated Mitophagy Regulation by Reactive Oxygen Species Alleviates Rocaglamide A-Induced Apoptosis in Pancreatic Cancer Cells.
MicroRNA-532-3p Suppresses Malignant Behaviors of Tongue Squamous Cell Carcinoma via Regulating CCR7.
ANLN and KDR Are Jointly Prognostic of Breast Cancer Survival and Can Be Modulated for Triple Negative Breast Cancer Control.
FKN Facilitates HK-2 Cell EMT and Tubulointerstitial Lesions via the Wnt/β-Catenin Pathway in a Murine Model of Lupus Nephritis.
Emodin Induced SREBP1-Dependent and SREBP1-Independent Apoptosis in Hepatocellular Carcinoma Cells.
Myricetin Attenuated Diabetes-Associated Kidney Injuries and Dysfunction via Regulating Nuclear Factor (Erythroid Derived 2)-Like 2 and Nuclear Factor-κB Signaling.
A Novel α-Galactosidase A Splicing Mutation Predisposes to Fabry Disease.
Sex Dependent Dysregulation of Hepatic Glucose Production in Lean Type 2 Diabetic Rats.
DNA Sensor IFI204 Contributes to Host Defense Against Staphylococcus aureus Infection in Mice.
Mechanosensitive Ion Channel Piezo1 Regulates Diet-Induced Adipose Inflammation and Systemic Insulin Resistance.
Phosphorylation of Microtubule- Associated Protein 4 Promotes Hypoxic Endothelial Cell Migration and Proliferation.
Transient Inhibition of mTORC1 Signaling Ameliorates Irradiation-Induced Liver Damage.
DDX23, an Evolutionary Conserved dsRNA Sensor, Participates in Innate Antiviral Responses by Pairing With TRIF or MAVS.
Structural and Functional Characterization of Hermetia illucens Larval Midgut.
Antiproliferative and Immunoregulatory Effects of Azelaic Acid Against Acute Myeloid Leukemia via the Activation of Notch Signaling Pathway.
Huang-Lian-Jie-Du Decoction Ameliorates Acute Ulcerative Colitis in Mice via Regulating NF-κB and Nrf2 Signaling Pathways and Enhancing Intestinal Barrier Function.
Muscle-Specific Sensitivity to Voluntary Physical Activity and Detraining.
USP37 Promotes Lung Cancer Cell Migration by Stabilizing Snail Protein via Deubiquitination.
Seneca Valley Virus 2C and 3Cpro Induce Apoptosis via Mitochondrion-Mediated Intrinsic Pathway.
Parental Renovascular Hypertension-Induced Autonomic Dysfunction in Male Offspring Is Improved by Prenatal or Postnatal Treatment With Hydrogen Sulfide.
Severe Fever With Thrombocytopenia Syndrome Virus-Induced Macrophage Differentiation Is Regulated by miR-146.
The Therapeutic Effects of Treadmill Exercise on Osteoarthritis in Rats by Inhibiting the HDAC3/NF-KappaB Pathway in vivo and in vitro.
Protective Effects of Dioscin Against Doxorubicin-Induced Hepatotoxicity Via Regulation of Sirt1/FOXO1/NF-κb Signal.
Apigenin Inhibits IL-6 Transcription and Suppresses Esophageal Carcinogenesis.
Decreased NDRG1 expression is associated with pregnancy loss in mice and attenuates the in vitro decidualization of endometrial stromal cells.
Knockdown of SP1/Syncytin1 axis inhibits the proliferation and metastasis through the AKT and ERK1/2 signaling pathways in non-small cell lung cancer.
HOXA10 induces BCL2 expression, inhibits apoptosis, and promotes cell proliferation in gastric cancer.
Telbivudine antagonizes TLR4 to inhibit the epithelial-to-mesenchymal transition in human proximal tubular epithelial cells in vitro.
Functional evaluation of a novel GLA causative mutation in Fabry disease.
Cholesterol transport through the peroxisome-ER membrane contacts tethered by PI(4,5)P2 and extended synaptotagmins.
The interaction between PLEKHG2 and ABL1 suppresses cell growth via the NF-κB signaling pathway in HEK293 cells.
Seneca Valley virus 2C and 3C inhibit type I interferon production by inducing the degradation of RIG-I.
Overexpression of matrix metalloproteinase-9 in breast cancer cell lines remarkably increases the cell malignancy largely via activation of transforming growth factor beta/SMAD signalling.
Essential role of IκBNS for in vivo CD4+ T-cell activation, proliferation, and Th1-cell differentiation during Listeria monocytogenes infection in mice.
Transforming growth factor β1 promotes fibroblast-like synoviocytes migration and invasion via TGF-β1/Smad signaling in rheumatoid arthritis.
MiR-212-3p inhibits cell proliferation and promotes apoptosis by targeting nuclear factor IA in bladder cancer.
Ubiquitin ligase TRIM65 promotes colorectal cancer metastasis by targeting ARHGAP35 for protein degradation.
Regional Ischemic Preconditioning Has Clinical Value in Cirrhotic HCC Through MAPK Pathways.
Bavachinin exhibits antitumor activity against non‑small cell lung cancer by targeting PPARγ.
Upregulation of EPS8L3 is associated with tumorigenesis and poor prognosis in patients with liver cancer.
Cancer associated fibroblasts are distinguishable from peri-tumor fibroblasts by biological characteristics in TSCC.
Probiotic effect on Helicobacter pylori attachment and inhibition of inflammation in human gastric epithelial cells.
Inhibition of polycomb repressor complex 2 ameliorates neointimal hyperplasia by suppressing trimethylation of H3K27 in vascular smooth muscle cells.
Functional daidzein enhances the anticancer effect of topotecan and reverses BCRP-mediated drug resistance in breast cancer.
SARI attenuates colon inflammation by promoting STAT1 degradation in intestinal epithelial cells.
In vitro effect of Pannexin 1 channel on the invasion and migration of I-10 testicular cancer cells via ERK1/2 signaling pathway.
Treatment with andrographolide sulfonate provides additional benefits to imipenem in a mouse model of Klebsiella pneumoniae pneumonia.
circMTO1 promotes tumorigenesis and chemoresistance of cervical cancer via regulating miR-6893.
Kinesin family member C1 accelerates bladder cancer cell proliferation and induces epithelial-mesenchymal transition via Akt/GSK3β signaling.
Angiopoietin-Like Protein 4 (ANGPTL4) Induces Retinal Pigment Epithelial Barrier Breakdown by Activating Signal Transducer and Activator of Transcription 3 (STAT3): Evidence from ARPE-19 Cells Under Hypoxic Condition and Diabetic Rats.
De novo synthesis of serine and glycine fuels purine nucleotide biosynthesis in human lung cancer tissues.
lncRNA NR_038323 Suppresses Renal Fibrosis in Diabetic Nephropathy by Targeting the miR-324-3p/DUSP1 Axis.
Myosin II isoforms play distinct roles in adherens junction biogenesis.
CD36 inhibits β-catenin/c-myc-mediated glycolysis through ubiquitination of GPC4 to repress colorectal tumorigenesis.
MiR-532-3p suppresses colorectal cancer progression by disrupting the ETS1/TGM2 axis-mediated Wnt/β-catenin signaling.
Ubiquitin ligase TRIM71 suppresses ovarian tumorigenesis by degrading mutant p53.
Inhibition of MCF-7 breast cancer cell proliferation by a synthetic peptide derived from the C-terminal sequence of Orai channel.
Ribavirin Induces Polyamine Depletion via Nucleotide Depletion to Limit Virus Replication.
microRNA arm-imbalance in part from complementary targets mediated decay promotes gastric cancer progression.
NRF2-dependent gene expression promotes ciliogenesis and Hedgehog signaling.
Targeting the IL-1β/IL-1Ra pathways for the aggregation of human islet amyloid polypeptide in an ex vivo organ culture system of the intervertebral disc.
Modulation of M2 macrophage polarization by the crosstalk between Stat6 and Trim24.
OPA1 overexpression ameliorates mitochondrial cristae remodeling, mitochondrial dysfunction, and neuronal apoptosis in prion diseases.
Retromer and TBC1D5 maintain late endosomal RAB7 domains to enable amino acid-induced mTORC1 signaling.
Recurrent GNAQ mutation encoding T96S in natural killer/T cell lymphoma.
Up-regulated cathepsin C induces macrophage M1 polarization through FAK-triggered p38 MAPK/NF-κB pathway.
Altered bile acid composition and disposition in a mouse model of non-alcoholic steatohepatitis.
Extensive disruption of protein interactions by genetic variants across the allele frequency spectrum in human populations.
Near-Infrared Light-Sensitive Nano Neuro-Immune Blocker Capsule Relieves Pain and Enhances the Innate Immune Response for Necrotizing Infection.
Transforming growth factor (TGF)-β1-induced miR-133a inhibits myofibroblast differentiation and pulmonary fibrosis.
miR-146a attenuates apoptosis and modulates autophagy by targeting TAF9b/P53 pathway in doxorubicin-induced cardiotoxicity.
Exosomal transfer of miR-501 confers doxorubicin resistance and tumorigenesis via targeting of BLID in gastric cancer.
Tributyltin exposure disturbs hepatic glucose metabolism in male mice.
Chronic administration of diethylnitrosamine to induce hepatocarcinogenesis and to evaluate its synergistic effect with other hepatotoxins in mice.
Characterization of a novel separase-interacting protein and candidate new securin, Eip1p, in the fungal pathogen Candida albicans.
The estrogen-regulated lncRNA H19/miR-216a-5p axis alters stromal cell invasion and migration via ACTA2 in endometriosis.
Inhibiting effect of microRNA-187-3p on osteogenic differentiation of osteoblast precursor cells by suppressing cannabinoid receptor type 2.
Increased miR-214 expression suppresses cell migration and proliferation in Hirschsprung disease by interacting with PLAGL2.
Baicalein and baicalin promote antitumor immunity by suppressing PD-L1 expression in hepatocellular carcinoma cells.
Potential role of M2 macrophage polarization in ventilator-induced lung fibrosis.
MiR-92a regulates endothelial progenitor cells (EPCs) by targeting GDF11 via activate SMAD2/3/FAK/Akt/eNOS pathway.
Direct Amplification of Tissue Factor:Factor VIIa Procoagulant Activity by Bile Acids Drives Intrahepatic Coagulation.
LINC00346 promotes pancreatic cancer progression through the CTCF-mediated Myc transcription.
HBx regulates transcription factor PAX8 stabilization to promote the progression of hepatocellular carcinoma.
Antioxidant activity of Coridius chinensis extracts on manganese-induced testicular damage in rats.
Genistein inhibits nasopharyngeal cancer stem cells through sonic hedgehog signaling.
MiR-100 suppresses inflammatory activation of microglia and neuronal apoptosis following spinal cord injury via TLR4/NF-κB pathway.
miR-29a promotes pathological cardiac hypertrophy by targeting the PTEN/AKT/mTOR signalling pathway and suppressing autophagy.
Silencing lncRNA SNHG6 suppresses proliferation and invasion of breast cancer cells through miR-26a/VASP axis.
NKAP functions as an oncogene in Ewing sarcoma cells partly through the AKT signaling pathway.
GSK343 induces autophagy and downregulates the AKT/mTOR signaling pathway in pancreatic cancer cells.
Ginsenoside Rg5 induces G2/M phase arrest, apoptosis and autophagy via regulating ROS-mediated MAPK pathways against human gastric cancer.
Hyperoside protects against heart failure-induced liver fibrosis in rats.
LXRα-mediated downregulation of EGFR suppress colorectal cancer cell proliferation.
LMX1B involved in the radioresistance, proliferation and migration of esophageal cancer cells.
Magnesium lithospermate B attenuates renal injury in 5/6 renal ablation/infarction rats by mitochondrial pathway of apoptosis.
ACT001, a novel PAI-1 inhibitor, exerts synergistic effects in combination with cisplatin by inhibiting PI3K/AKT pathway in glioma.
Strong anion exchange-mediated phosphoproteomics reveals extensive human non-canonical phosphorylation.
Cichorium intybus L. Extract Suppresses Experimental Gout by Inhibiting the NF-κB and NLRP3 Signaling Pathways.
Improvement of Mitochondrial Activity and Fibrosis by Resveratrol Treatment in Mice with Schistosoma japonicum Infection.
Activated spinal astrocytes contribute to the later phase of carrageenan-induced prostatitis pain.
YTHDF1 links hypoxia adaptation and non-small cell lung cancer progression.
MicroRNA-29a Suppresses CD36 to Ameliorate High Fat Diet-Induced Steatohepatitis and Liver Fibrosis in Mice.
The protective effect of Phellinus linteus decoction on podocyte injury in the kidney of FSGS rats.
Systematically characterize the clinical and biological significances of 1p19q genes in 1p/19q non-codeletion glioma.
N6-methyladenosine modification of circNSUN2 facilitates cytoplasmic export and stabilizes HMGA2 to promote colorectal liver metastasis.
Exosomal and extracellular HMGB1 have opposite effects on SASH1 expression in rat astrocytes and glioma C6 cells.
Bromodomain-containing protein 4 contributes to renal fibrosis through the induction of epithelial-mesenchymal transition.
Human Umbilical Cord-Derived Mesenchymal Stem Cells Relieve Hind Limb Ischemia by Promoting Angiogenesis in Mice.
Dystroglycan is involved in the activation of ERK pathway inducing the change of AQP4 expression in scratch-injured astrocytes.
Endothelial cell pyroptosis plays an important role in Kawasaki disease via HMGB1/RAGE/cathespin B signaling pathway and NLRP3 inflammasome activation.
A circular RNA from APC inhibits the proliferation of diffuse large B-cell lymphoma by inactivating Wnt/β-catenin signaling via interacting with TET1 and miR-888.
Polyphenol-Rich Extracts from Toona sinensis Bark and Fruit Ameliorate Free Fatty Acid-Induced Lipogenesis through AMPK and LC3 Pathways.
TMEM18 inhibits osteogenic differentiation of rat bone marrow-derived mesenchymal stem cells by inactivating β-catenin.
Genetic loss of Gas6/Mer pathway attenuates silica-induced lung inflammation and fibrosis in mice.
Serum miR-221-3p as a new potential biomarker for depressed mood in perioperative patients.
Prolonged neutrophil retention in the wound impairs zebrafish heart regeneration after cryoinjury.
lncRNA ABHD11-AS1, regulated by the EGFR pathway, contributes to the ovarian cancer tumorigenesis by epigenetically suppressing TIMP2.
Combined MEK inhibition and tumor-associated macrophages depletion suppresses tumor growth in a triple-negative breast cancer mouse model.
Role of miR-214 in regulation of β-catenin and the malignant phenotype of melanoma.
Allele-selective lowering of mutant HTT protein by HTT-LC3 linker compounds.
Structural characterization and biological function of bivalent binding of CD2AP to intrinsically disordered domain of chikungunya virus nsP3 protein.
Upregulated PDK4 expression is a sensitive marker of increased fatty acid oxidation.
Dehydrogenase/reductase SDR family member 2 silencing sensitizes an oxaliplatin‑resistant cell line to oxaliplatin by inhibiting excision repair cross‑complementing group 1 protein expression.
KDELR2 Promotes Glioblastoma Tumorigenesis Targeted by HIF1a via mTOR Signaling Pathway.
The digestive system of the adult Hermetia illucens (Diptera: Stratiomyidae): morphological features and functional properties.
The protective effect of lithocholic acid on the intestinal epithelial barrier is mediated by the vitamin D receptor via a SIRT1/Nrf2 and NF-κB dependent mechanism in Caco-2 cells.
Transcription factor 7-like 2-associated signaling mechanism in regulating cementum generation by the NF-κB pathway.
EphA8 acts as an oncogene and contributes to poor prognosis in gastric cancer via regulation of ADAM10.
The miR-27a-3p/USP25 axis participates in the pathogenesis of recurrent miscarriage by inhibiting trophoblast migration and invasion.
GSK-3β inhibition protects the rat heart from the lipopolysaccharide-induced inflammation injury via suppressing FOXO3A activity.
Long non-coding RNA cardiac hypertrophy-associated regulator governs cardiac hypertrophy via regulating miR-20b and the downstream PTEN/AKT pathway.
TMPO-AS1 promotes cervical cancer progression by upregulating RAB14 via sponging miR-577.
Knockdown of long noncoding RNA DLEU1 suppresses the progression of renal cell carcinoma by downregulating the Akt pathway.
Deficiency of PTEN leads to aberrant chromosome segregation through downregulation of MAD2.
Downregulation of transgelin 2 promotes breast cancer metastasis by activating the reactive oxygen species/nuclear factor‑κB signaling pathway.
Identification of two novel RHO mutations in Chinese retinitis pigmentosa patients.
SNX3 suppresses the migration and invasion of colorectal cancer cells by reversing epithelial-to-mesenchymal transition via the β-catenin pathway.
Exogenous hydrogen sulfide protects against high glucose-induced apoptosis and oxidative stress by inhibiting the STAT3/HIF-1α pathway in H9c2 cardiomyocytes.
C2-lacking isoform of Nedd4-2 regulates excitatory synaptic strength through GluA1 ubiquitination-independent mechanisms.
Atsttrin reduces lipopolysaccharide-induced neuroinflammation by inhibiting the nuclear factor kappa B signaling pathway.
C9orf72 intermediate repeats are associated with corticobasal degeneration, increased C9orf72 expression and disruption of autophagy.
Delta-aminolevulinic acid synthase 2 expression in combination with iron as modifiers of disease severity in erythropoietic protoporphyria.
Transmural pressure drives proliferation of human arterial smooth muscle cells via mechanism associated with NADPH oxidase and Survivin.
IL-22 suppresses HSV-2 replication in human cervical epithelial cells.
miR-9-5p attenuates ischemic stroke through targeting ERMP1-mediated endoplasmic reticulum stress.
Serum proteomics analysis based on label-free revealed the protective effect of Chinese herbal formula Gu-Ben-Fang-Xiao.
G9a and histone deacetylases are crucial for Snail2-mediated E-cadherin repression and metastasis in hepatocellular carcinoma.
The metabolic regulator small heterodimer partner contributes to the glucose and lipid homeostasis abnormalities induced by hepatitis C virus infection.
LINC00467 promotes cell proliferation and stemness in lung adenocarcinoma by sponging miR-4779 and miR-7978.
Double-stranded RNA deaminase ADAR1 promotes the Zika virus replication by inhibiting the activation of protein kinase PKR.
Microtubule destabilization caused by silicate via HDAC6 activation contributes to autophagic dysfunction in bone mesenchymal stem cells.
Astaxanthin protects against osteoarthritis via Nrf2: a guardian of cartilage homeostasis.
Long noncoding RNA LINC01111 suppresses pancreatic cancer aggressiveness by regulating DUSP1 expression via microRNA-3924.
ZFP161 regulates replication fork stability and maintenance of genomic stability by recruiting the ATR/ATRIP complex.
CD105 Is Expressed in Ovarian Cancer Precursor Lesions and Is Required for Metastasis to the Ovary.
Tissue plasminogen activator disrupts the blood-brain barrier through increasing the inflammatory response mediated by pericytes after cerebral ischemia.
Efficient Delivery of Therapeutic siRNA by Fe3O4 Magnetic Nanoparticles into Oral Cancer Cells.
Chemerin-induced macrophages pyroptosis in fetal brain tissue leads to cognitive disorder in offspring of diabetic dams.
Viral Nonstructural Protein 1 Induces Mitochondrion-Mediated Apoptosis in Mink Enteritis Virus Infection.
Nitidine chloride induces S phase cell cycle arrest and mitochondria-dependent apoptosis in HaCaT cells and ameliorates skin lesions in psoriasis-like mouse models.
Aberrant activation of RPB1 is critical for cell overgrowth in acute myeloid leukemia.
A thiazole-derived oridonin analogue exhibits antitumor activity by directly and allosterically inhibiting STAT3.
β-Caryophyllene protects against ischemic stroke by promoting polarization of microglia toward M2 phenotype via the TLR4 pathway.
A dual functional ruthenium arene complex induces differentiation and apoptosis of acute promyelocytic leukemia cells.
The miR-28-5p-CAMTA2 axis regulates colon cancer progression via Wnt/β-catenin signaling.
SPOP inhibits mice pancreatic stellate cell activation by promoting FADD degradation in cerulein-induced chronic pancreatitis.
Prematurity blunts the feeding-induced stimulation of translation initiation signaling and protein synthesis in muscle of neonatal piglets.
Aurone derivatives as Vps34 inhibitors that modulate autophagy.
Regulation of insulin resistance by targeting the insulin-like growth factor 1 receptor with microRNA-122-5p in hepatic cells.
RPS7 promotes cell migration through targeting epithelial-mesenchymal transition in prostate cancer.
Identification of genes with universally upregulated or downregulated expressions in colorectal cancer.
Taurine alleviates repression of betaine-homocysteine S-methyltransferase and significantly improves the efficacy of long-term betaine treatment in a mouse model of cystathionine β-synthase-deficient homocystinuria.
Adipose-Specific Lipin-1 Overexpression Renders Hepatic Ferroptosis and Exacerbates Alcoholic Steatohepatitis in Mice.
Serine/arginine protein-specific kinase 2 promotes the development and progression of pancreatic cancer by downregulating Numb and p53.
MicroRNA-92a promotes vascular smooth muscle cell proliferation and migration through the ROCK/MLCK signalling pathway.
Ectopic expression of miR-944 impairs colorectal cancer cell proliferation and invasion by targeting GATA binding protein 6.
The pattern-recognition molecule mindin binds integrin Mac-1 to promote macrophage phagocytosis via Syk activation and NF-κB p65 translocation.
The RNA N6-methyladenosine modification landscape of human fetal tissues.
ERα and Wnt/β‑catenin signaling pathways are involved in angelicin‑dependent promotion of osteogenesis.
β-Catenin and Yes-Associated Protein 1 Cooperate in Hepatoblastoma Pathogenesis.
A novel function of anaphase promoting complex subunit 10 in tumor progression in non-small cell lung cancer.
Demethylation of the HACE1 gene promoter inhibits the proliferation of human liver cancer cells.
Upregulated forkhead-box A3 elevates the expression of forkhead-box A1 and forkhead-box A2 to promote metastasis in esophageal cancer.
Nano hydroxyapatite induces glioma cell apoptosis by suppressing NF-κB signaling pathway.
Attenuation of interferon regulatory factor 7 activity in local infectious sites of trachea and lung for preventing the development of acute lung injury caused by influenza A virus.
SMCR8 negatively regulates AKT and MTORC1 signaling to modulate lysosome biogenesis and tissue homeostasis.
The ALS-FTD-linked gene product, C9orf72, regulates neuronal morphogenesis via autophagy.
FAM175B promotes apoptosis by inhibiting ATF4 ubiquitination in esophageal squamous cell carcinoma.
Nrf2 controls iron homeostasis in haemochromatosis and thalassaemia via Bmp6 and hepcidin.
Sox17 is required for endothelial regeneration following inflammation-induced vascular injury.
Inhibiting Glutamine-Dependent mTORC1 Activation Ameliorates Liver Cancers Driven by β-Catenin Mutations.
Thyrotropin aggravates atherosclerosis by promoting macrophage inflammation in plaques.
Adipose HuR protects against diet-induced obesity and insulin resistance.
USP36 protects proximal tubule cells from ischemic injury by stabilizing c-Myc and SOD2.
p53 suppression is essential for oncogenic SPAG5 upregulation in lung adenocarcinoma.
HMGB1 contributes to SASH1 methylation to attenuate astrocyte adhesion.
Inhibition of the IGF-1-PI3K-Akt-mTORC2 pathway in lipid rafts increases neuronal vulnerability in a genetic lysosomal glycosphingolipidosis.
PLA Electrospun Scaffolds for Three-Dimensional Triple-Negative Breast Cancer Cell Culture.
Shen Shuai IIRecipe attenuates renal injury and fibrosis in chronic kidney disease by regulating NLRP3 inflammasome and Sirt1/Smad3 deacetylation pathway.
Isodunnianol alleviates doxorubicin-induced myocardial injury by activating protective autophagy.
Estrogen negatively regulates the renal epithelial sodium channel (ENaC) by promoting Derlin-1 expression and AMPK activation.
Tumor Cell "Slimming" Regulates Tumor Progression through PLCL1/UCP1-Mediated Lipid Browning.
M2 macrophages promote NSCLC metastasis by upregulating CRYAB.
Triptolide prevents proliferation and migration of Esophageal Squamous Cell Cancer via MAPK/ERK signaling pathway.
Oral Administration of a Select Mixture of Lactobacillus and Bacillus Alleviates Inflammation and Maintains Mucosal Barrier Integrity in the Ileum of Pigs Challenged with Salmonella Infantis.
Hic-5 regulates Src-induced invadopodia rosette formation and organization.
FGFR2 Promotes Expression of PD-L1 in Colorectal Cancer via the JAK/STAT3 Signaling Pathway.
Sodium ferulate protects against influenza virus infection by activation of the TLR7/9-MyD88-IRF7 signaling pathway and inhibition of the NF-κB signaling pathway.
The Glycoprotein and Nucleocapsid Protein of Hantaviruses Manipulate Autophagy Flux to Restrain Host Innate Immune Responses.
Cynomorium songaricum Rupr demonstrates phytoestrogenic or phytoandrogenic like activities that attenuates benign prostatic hyperplasia via regulating steroid 5-α-reductase.
Anterior Gradient-2 monoclonal antibody inhibits lung cancer growth and metastasis by upregulating p53 pathway and without exerting any toxicological effects: A preclinical study.
USP39 regulates DNA damage response and chemo-radiation resistance by deubiquitinating and stabilizing CHK2.
Astragaloside IV Regulates the PI3K/Akt/HO-1 Signaling Pathway and Inhibits H9c2 Cardiomyocyte Injury Induced by Hypoxia-Reoxygenation.
Inactivation of Cyclic AMP Response Element Transcription Caused by Constitutive p38 Activation Is Mediated by Hyperphosphorylation-Dependent CRTC2 Nucleocytoplasmic Transport.
Fatty acid-binding protein 3 contributes to ischemic heart injury by regulating cardiac myocyte apoptosis and MAPK pathways.
Inhibition of mitochondrial complex I activity attenuates neointimal hyperplasia by inhibiting smooth muscle cell proliferation and migration.
Reactivation of nonsense-mediated mRNA decay protects against C9orf72 dipeptide-repeat neurotoxicity.
Sirt3 mediates the protective effect of hydrogen in inhibiting ROS-induced retinal senescence.
Oxytocin facilitates the proliferation, migration and osteogenic differentiation of human periodontal stem cells in vitro.
Nr5a2 promotes cancer stem cell properties and tumorigenesis in nonsmall cell lung cancer by regulating Nanog.
MicroRNA-186 is associated with hypoxia-inducible factor-1α expression in chronic obstructive pulmonary disease.
Gallic Acid Suppresses Cardiac Hypertrophic Remodeling and Heart Failure.
Herbal decoctosome is a novel form of medicine.
Pb disrupts autophagic flux through inhibiting the formation and activity of lysosomes in neural cells.
Role of heparan sulfate in the Zika virus entry, replication, and cell death.
NS38 is required for aquareovirus replication via interaction with viral core proteins and host eIF3A.
Continuous translation of circularized mRNA improves recombinant protein titer.
Regulation of Neurotransmitter Release by Amyloid Precursor Protein Through Synapsin Phosphorylation.
Bromodomain‑containing protein 7 sensitizes breast cancer cells to paclitaxel by activating Bcl2‑antagonist/killer protein.
miR-4739 mediates pleural fibrosis by targeting bone morphogenetic protein 7.
3D human bone marrow stromal and endothelial cell spheres promote bone healing in an osteogenic niche.
Oncostatin M-induced upregulation of SDF-1 improves Bone marrow stromal cell migration in a rat middle cerebral artery occlusion stroke model.
PARylation regulates stress granule dynamics, phase separation, and neurotoxicity of disease-related RNA-binding proteins.
β‑elemene inhibits oxygen‑induced retinal neovascularization via promoting miR‑27a and reducing VEGF expression.
Modulation of α-adrenoceptor signalling protects photoreceptors after retinal detachment by inhibiting oxidative stress and inflammation.
NF-κB and Poly (ADP-ribose) Polymerase 1 Form a Positive Feedback Loop that Regulates DNA Repair in Acute Myeloid Leukemia Cells.
miRNA profiling in the hippocampus of attention-deficit/hyperactivity disorder rats.
MET mutation causes muscular dysplasia and arthrogryposis.
MLKL deficiency inhibits DSS-induced colitis independent of intestinal microbiota.
Combinatory FK506 and Minocycline Treatment Alleviates Prion-Induced Neurodegenerative Events via Caspase-Mediated MAPK-NRF2 Pathway.
Circadian control of stress granules by oscillating EIF2α.
Neuroprotective Effect of Dioscin on the Aging Brain.
Silencing of XRCC4 increases radiosensitivity of triple-negative breast cancer cells.
Cysteine Dioxygenase Regulates the Epithelial Morphogenesis of Mammary Gland via Cysteine Sulfinic Acid.
Viral-Mediated AURKB Cleavage Promotes Cell Segregation and Tumorigenesis.
MicroRNA-29a Disrupts DNMT3b to Ameliorate Diet-Induced Non-Alcoholic Steatohepatitis in Mice.
H2S restores the cardioprotective effects of ischemic post-conditioning by upregulating HB-EGF/EGFR signaling.
Ribosomal Proteins Regulate MHC Class I Peptide Generation for Immunosurveillance.
Genetically Encoded FapR-NLuc as a Biosensor to Determine Malonyl-CoA in Situ at Subcellular Scales.
A GPR17-cAMP-Lactate Signaling Axis in Oligodendrocytes Regulates Whole-Body Metabolism.
p53-targeted lincRNA-p21 acts as a tumor suppressor by inhibiting JAK2/STAT3 signaling pathways in head and neck squamous cell carcinoma.
Porcine Hemagglutinating Encephalomyelitis Virus Activation of the Integrin α5β1-FAK-Cofilin Pathway Causes Cytoskeletal Rearrangement To Promote Its Invasion of N2a Cells.
PRL-3 Promotes Ubiquitination and Degradation of AURKA and Colorectal Cancer Progression via Dephosphorylation of FZR1.
HOXD-AS1 promotes the epithelial to mesenchymal transition of ovarian cancer cells by regulating miR-186-5p and PIK3R3.
Candidate-based screening via gene modulation in human neurons and astrocytes implicates FERMT2 in Aβ and TAU proteostasis.
In Vitro and In Vivo Anti-Inflammatory Effects of Polyphyllin VII through Downregulating MAPK and NF-κB Pathways.
Molecular characterization of caspase-8-like and its expression induced by microcystin-LR in grass carp (Ctenopharygodon idella).
Defective Central Immune Tolerance Induced by High-Dose D-Galactose Resembles Aging.
Exosomal cyclophilin A as a novel noninvasive biomarker for Epstein-Barr virus associated nasopharyngeal carcinoma.
Activation of cGMP/PKG/p65 signaling associated with PDE5-Is downregulates CCL5 secretion by CD8 + T cells in benign prostatic hyperplasia.
Minimally modified low-density lipoprotein upregulates the ETB and α1 receptors in mouse mesenteric arteries in vivo by activating the PI3K/Akt pathway.
Deficiency of ZnT8 Promotes Adiposity and Metabolic Dysfunction by Increasing Peripheral Serotonin Production.
Activated CRH receptors inhibit autophagy by repressing conversion of LC3BI to LC3BII.
A comprehensive study on donor-matched comparisons of three types of mesenchymal stem cells-containing cells from human dental tissue.
Effects of 3-dimensional Bioprinting Alginate/Gelatin Hydrogel Scaffold Extract on Proliferation and Differentiation of Human Dental Pulp Stem Cells.
The circRNA circPTPRA suppresses epithelial-mesenchymal transitioning and metastasis of NSCLC cells by sponging miR-96-5p.
FasL on decidual macrophages mediates trophoblast apoptosis: A potential cause of recurrent miscarriage.
Obesity-associated family with sequence similarity 13, member A (FAM13A) is dispensable for adipose development and insulin sensitivity.
Probenecid Relieves Cerebral Dysfunction of Sepsis by Inhibiting Pannexin 1-Dependent ATP Release.
Early Pattern of Epstein-Barr Virus Infection in Gastric Epithelial Cells by "Cell-in-cell".
Reduced asymmetric dimethylarginine accumulation through inhibition of the type I protein arginine methyltransferases promotes renal fibrosis in obstructed kidneys.
Suppression of puerarin on polymethylmethacrylate-induced lesion of peri-implant by inhibiting NF-κB activation in vitro and in vivo.
An SOD1 deficiency aggravates proteasome inhibitor bortezomib-induced testicular damage in mice.
The p53/miRNAs/Ccna2 pathway serves as a novel regulator of cellular senescence: Complement of the canonical p53/p21 pathway.
Enhanced responsiveness of platelets to vicagrel in IL-10-deficient mice through STAT3-dependent up-regulation of the hydrolase arylacetamide deacetylase in the intestine.
Inhibition of Wee1 sensitizes AML cells to ATR inhibitor VE-822-induced DNA damage and apoptosis.
AC002454.1 and CDK6 synergistically promote endometrial cell migration and invasion in endometriosis.
Hydrogen sulfide protects against DSS-induced colitis by inhibiting NLRP3 inflammasome.
Amplification of USP13 drives non-small cell lung cancer progression mediated by AKT/MAPK signaling.
Antithrombotic Effect of shRNA Target F12 Mediated by Adeno-Associated Virus.
Insulin-like growth factor-1 attenuates oxidative stress-induced hepatocyte premature senescence in liver fibrogenesis via regulating nuclear p53-progerin interaction.
Death-associated protein kinase 3 deficiency alleviates vascular calcification via AMPK-mediated inhibition of endoplasmic reticulum stress.
Alternative transcription start site selection in ACSS2 controls its nuclear localization and promotes ribosome biosynthesis in hepatocellular carcinoma.
NLRC5 inhibits neointima formation following vascular injury and directly interacts with PPARγ.
Pervasive Chromatin-RNA Binding Protein Interactions Enable RNA-Based Regulation of Transcription.
Transcriptional Regulation of gga-miR-451 by AhR:Arnt in Mycoplasma gallisepticum (HS Strain) Infection.
miR-211 facilitates platinum chemosensitivity by blocking the DNA damage response (DDR) in ovarian cancer.
Identification of metabolic vulnerabilities of receptor tyrosine kinases-driven cancer.
Low Polymerase Activity Attributed to PA Drives the Acquisition of the PB2 E627K Mutation of H7N9 Avian Influenza Virus in Mammals.
Induction of Fibrosis and Autophagy in Kidney Cells by Vinyl Chloride.
Cellular Interleukin Enhancer-Binding Factor 2, ILF2, Inhibits Japanese Encephalitis Virus Replication In Vitro.
Insulin transcriptionally down-regulates carboxylesterases through pregnane X receptor in an Akt-dependent manner.
NOL12 Repression Induces Nucleolar Stress-Driven Cellular Senescence and Is Associated with Normative Aging.
Dihydromyricetin alleviates acetaminophen-induced liver injury via the regulation of transformation, lipid homeostasis, cell death and regeneration.
Fine particulate matter-induced cardiovascular injury is associated with NLRP3 inflammasome activation in Apo E-/- mice.
Heartland virus antagonizes type I and III interferon antiviral signaling by inhibiting phosphorylation and nuclear translocation of STAT2 and STAT1.
Small molecule inhibitor of TGF-β signaling enables robust osteogenesis of autologous GMSCs to successfully repair minipig severe maxillofacial bone defects.
CDK9 modulates circadian clock by attenuating REV-ERBα activity.
Arsenic trioxide inhibits EMT in hepatocellular carcinoma by promoting lncRNA MEG3 via PKM2.
Targeting ATGL to rescue BSCL2 lipodystrophy and its associated cardiomyopathy.
microRNA-378a Regulates the Reactive Oxygen Species (ROS)/Phosphatidylinositol 3-Kinases (PI3K)/AKT Signaling Pathway in Human Lens Epithelial Cells and Cataract.
Role of TMPRSS4 Modulation in Breast Cancer Cell Proliferation.
Nrf2 deficiency aggravates Angiotensin II-induced cardiac injury by increasing hypertrophy and enhancing IL-6/STAT3-dependent inflammation.
Aerobic exercise regulates synaptic transmission and reactive oxygen species production in the paraventricular nucleus of spontaneously hypertensive rats.
Esrrb plays important roles in maintaining self-renewal of trophoblast stem cells (TSCs) and reprogramming somatic cells to induced TSCs.
Cardamonin from a medicinal herb protects against LPS-induced septic shock by suppressing NLRP3 inflammasome.
IL-25 promotes cisplatin resistance of lung cancer cells by activating NF-κB signaling pathway to increase of major vault protein.
Anti-inflammatory and antitumour activity of various extracts and compounds from the fruits of Piper longum L.
MicroRNA-135b alleviates MPP+-mediated Parkinson's disease in in vitro model through suppressing FoxO1-induced NLRP3 inflammasome and pyroptosis.
APS could potentially activate hepatic insulin signaling in HFD-induced IR mice.
MicroRNA-221 sensitizes chronic myeloid leukemia cells to imatinib by targeting STAT5.
Comparison of intracellular responses between HBV genotype A and C infection in human hepatocyte chimeric mice.
Clearance of apoptotic cells by mesenchymal stem cells contributes to immunosuppression via PGE2.
The potential role of pregnancy-associated plasma protein-A2 in angiogenesis and development of preeclampsia.
Luteolin suppresses colorectal cancer cell metastasis via regulation of the miR‑384/pleiotrophin axis.
Dynasore Suppresses mTORC1 Activity and Induces Autophagy to Regulate the Clearance of Protein Aggregates in Neurodegenerative Diseases.
Reduction of PGRN increased fibrosis during skin wound healing in mice.
Activation of prostaglandin EP4 receptor attenuates the induction of cyclooxygenase-2 expression by EP2 receptor activation in human amnion fibroblasts: implications for parturition.
Resveratrol targets TyrRS acetylation to protect against radiation-induced damage.
Notch signaling activation induces cell death in MAPKi-resistant melanoma cells.
Molecular basis of vasohibins-mediated detyrosination and its impact on spindle function and mitosis.
Alcohol dehydrogenase of Candida albicans triggers differentiation of THP-1 cells into macrophages.
Neuroprotection of Fasting Mimicking Diet on MPTP-Induced Parkinson's Disease Mice via Gut Microbiota and Metabolites.
Harnessing the anti-cancer natural product nimbolide for targeted protein degradation.
RTN1-C is involved in high glucose-aggravated neuronal cell subjected to oxygen-glucose deprivation and reoxygenation injury via endoplasmic reticulum stress.
Long-term pulmonary exposure to multi-walled carbon nanotubes promotes breast cancer metastatic cascades.
Aqueous extract of Salvia miltiorrhiza Bunge-Radix Puerariae herb pair ameliorates diabetic vascular injury by inhibiting oxidative stress in streptozotocin-induced diabetic rats.
Effect of Hypoxia on the Muscle Fiber Switching Signal Pathways CnA/NFATc1 and Myostatin in Mouse Myocytes.
Hsa_circ_0023404 enhances cervical cancer metastasis and chemoresistance through VEGFA and autophagy signaling by sponging miR-5047.
Taurine protects against arsenic trioxide-induced insulin resistance via ROS-Autophagy pathway in skeletal muscle.
Long noncoding RNA actin filament-associated protein 1 antisense RNA 1 promotes malignant phenotype through binding with lysine-specific demethylase 1 and repressing HMG box-containing protein 1 in non-small-cell lung cancer.
Lysine glutarylation in human sperm is associated with progressive motility.
microRNA-16-5p promotes 3T3-L1 adipocyte differentiation through regulating EPT1.
Comparative interactome analysis reveals distinct and overlapping properties of Raf family kinases.
Long noncoding RNA PCAT1, a novel serum-based biomarker, enhances cell growth by sponging miR-326 in oesophageal squamous cell carcinoma.
TSPAN12 Precedes Tumor Proliferation by Cell Cycle Control in Ovarian Cancer.
LncRNA-H19 promotes hepatic lipogenesis by directly regulating miR-130a/PPARγ axis in non-alcoholic fatty liver disease.
A novel RP2 missense mutation Q158P identified in an X-linked retinitis pigmentosa family impaired RP2 protein stability.
Melatonin attenuates cadmium-induced ovulatory dysfunction by suppressing endoplasmic reticulum stress and cell apoptosis.
MiR-205 mediated APC regulation contributes to pancreatic cancer cell proliferation.
Osteoprotegerin (OPG) Promotes Recruitment of Endothelial Progenitor Cells (EPCs) via CXCR4 Signaling Pathway to Improve Bone Defect Repair.
Simultaneous knockdown of YAP and TAZ increases apoptosis of hepatocellular carcinoma cells under hypoxic condition.
Diallyl Disulfide Induces Apoptosis and Autophagy in Human Osteosarcoma MG-63 Cells through the PI3K/Akt/mTOR Pathway.
Blood autophagy defect causes accelerated non-hematopoietic organ aging.
Inhibitory Effects of Oxymatrine on Transdifferentiation of Neonatal Rat Cardiac Fibroblasts to Myofibroblasts Induced by Aldosterone via Keap1/Nrf2 Signaling Pathways In Vitro.
SFRS11 Loss Leads to Aging-Associated Cognitive Decline by Modulating LRP8 and ApoE.
Structural and functional analyses of hepatitis B virus X protein BH3-like domain and Bcl-xL interaction.
CD4 Expression and Env Conformation Are Critical for HIV-1 Restriction by SERINC5.
A novel, highly-water-soluble apigenin derivative provides neuroprotection following ischemia in male rats by regulating the ERK/Nrf2/HO-1 pathway.
LncRNA FOXD2-AS1 plays an oncogenic role in hepatocellular carcinoma through epigenetically silencing CDKN1B(p27) via EZH2.
Matrine inhibits IL-1β secretion in primary porcine alveolar macrophages through the MyD88/NF-κB pathway and NLRP3 inflammasome.
KHDRBS3 regulates the permeability of blood-tumor barrier via cDENND4C/miR-577 axis.
Insulin-like growth factor 2 mRNA binding protein 2 promotes aerobic glycolysis and cell proliferation in pancreatic ductal adenocarcinoma via stabilizing GLUT1 mRNA.
Knockdown ATG4C inhibits gliomas progression and promotes temozolomide chemosensitivity by suppressing autophagic flux.
Metformin facilitates the proliferation, migration, and osteogenic differentiation of periodontal ligament stem cells in vitro.
Activation of 20-HETE/PPARs involved in reno-therapeutic effect of naringenin on diabetic nephropathy.
Toxicological exploration of peptide-based cationic liposomes in siRNA delivery.
Exosomal miR-1229 derived from colorectal cancer cells promotes angiogenesis by targeting HIPK2.
Phenylephrine Alleviates 131I Radiation Damage in Submandibular Gland Through Maintaining Mitochondrial Homeostasis.
Extracellular matrix remodeling effects of serum amyloid A1 in the human amnion: Implications for fetal membrane rupture.
Overexpression of P2X4 receptor in Schwann cells promotes motor and sensory functional recovery and remyelination via BDNF secretion after nerve injury.
Neuroprotective effects of Astilbin on MPTP-induced Parkinson's disease mice: Glial reaction, α-synuclein expression and oxidative stress.
HUS1 checkpoint clamp component (HUS1) is a potential tumor suppressor in primary hepatocellular carcinoma.
ERp57‑small interfering RNA silencing can enhance the sensitivity of drug‑resistant human ovarian cancer cells to paclitaxel.
MiR-20a Plays a Key Regulatory Role in the Repair of Spinal Cord Dorsal Column Lesion via PDZ-RhoGEF/RhoA/GAP43 Axis in Rat.
Heme oxygenase-1 prevents heart against myocardial infarction by attenuating ischemic injury-induced cardiomyocytes senescence.
DPSCs seeded in acellular nerve grafts processed by Myroilysin improve nerve regeneration.
Dual regulatory role of CCNA2 in modulating CDK6 and MET-mediated cell-cycle pathway and EMT progression is blocked by miR-381-3p in bladder cancer.
Chromium(VI) promotes cell migration through targeting epithelial-mesenchymal transition in prostate cancer.
MiR-10b suppresses the growth and metastasis of colorectal cancer cell by targeting FGF13.
Characterization and proteomic profiling of pancreatic cancer-derived serum exosomes.
Combined detection of estrogen and tumor markers is an important reference factor in the diagnosis and prognosis of lung cancer.
EETs/PPARs activation together mediates the preventive effect of naringenin in high glucose-induced cardiomyocyte hypertrophy.
Ginsenoside Rd contributes the attenuation of cardiac hypertrophy in vivo and in vitro.
Role of bone morphogenetic protein-2/4 in astrocyte activation in neuropathic pain.
Zingerone Nanotetramer Strengthened the Polypharmacological Efficacy of Zingerone on Human Hepatoma Cell Lines.
A scorpion venom peptide Ev37 restricts viral late entry by alkalizing acidic organelles.
The deregulation of STIM1 and store operative calcium entry impaired aortic smooth muscle cells contractility in aortic medial degeneration.
DDX19 Inhibits Type I Interferon Production by Disrupting TBK1-IKKε-IRF3 Interactions and Promoting TBK1 and IKKε Degradation.
Atoh1 Controls Primary Cilia Formation to Allow for SHH-Triggered Granule Neuron Progenitor Proliferation.
The Plk1 kinase negatively regulates the Hedgehog signaling pathway by phosphorylating Gli1.
Acetaldehyde dehydrogenase 2 interactions with LDLR and AMPK regulate foam cell formation.
LncRNA SNHG12 inhibits miR-199a to upregulate SIRT1 to attenuate cerebral ischemia/reperfusion injury through activating AMPK signaling pathway.
Sphingosine 1 phosphate receptor-1 (S1P1) promotes tumor-associated regulatory T cell expansion: leading to poor survival in bladder cancer.
Genome-wide CRISPR Analysis Identifies Substrate-Specific Conjugation Modules in ER-Associated Degradation.
Transfer of Extracellular Vesicle-Associated-RNAs Induces Drug Resistance in ALK-Translocated Lung Adenocarcinoma.
Cathepsin C promotes microglia M1 polarization and aggravates neuroinflammation via activation of Ca2+-dependent PKC/p38MAPK/NF-κB pathway.
Hepatitis B e Antigen Inhibits NF-κB Activity by Interrupting K63-Linked Ubiquitination of NEMO.
Binding of cellular nucleolin with the viral core RNA G-quadruplex structure suppresses HCV replication.
N6-methyladenosine modification and METTL3 modulate enterovirus 71 replication.
Histone Demethylase KDM4B Promotes DNA Damage by Activating Long Interspersed Nuclear Element-1.
FAPP2 promotes tumor cell growth in human colon cancer through activation of Wnt signaling.
Piezo1 mediates angiogenesis through activation of MT1-MMP signaling.
Different Isoforms of the Neuronal Guidance Molecule Slit2 Directly Cause Chemoattraction or Chemorepulsion of Human Neutrophils.
MiR-26a-5p Inhibits Cell Proliferation and Enhances Doxorubicin Sensitivity in HCC Cells via Targeting AURKA.
Colon Cancer Cell Secretes EGF to Promote M2 Polarization of TAM Through EGFR/PI3K/AKT/mTOR Pathway.
MMP13 inhibition rescues cognitive decline in Alzheimer transgenic mice via BACE1 regulation.
Genotoxic stress causes the accumulation of DNA-dependent protein kinase catalytic subunit phosphorylated at serine 2056 at nuclear speckles and alters pre-mRNA alternative splicing.
High expression of SLC17A9 correlates with poor prognosis in colorectal cancer.
MicroRNA-5195-3p plays a suppressive role in cell proliferation, migration and invasion by targeting MYO6 in human non-small cell lung cancer.
Early onset developmental delay and epilepsy in pediatric patients with WDR45 variants.
Tunicamycin enhances the suppressive effects of cisplatin on lung cancer growth through PTX3 glycosylation via AKT/NF-κB signaling pathway.
Increased levels of serum pigment epithelium-derived factor aggravate proteinuria via induction of podocyte actin rearrangement.
Rapid depletion of ESCRT protein Vps4 underlies injury-induced autophagic impediment and Wallerian degeneration.
CXCR4 enhances cisplatin resistance of human tongue squamous cell carcinoma.
Chlamydia trachomatis plasmid-encoded protein Pgp3 inhibits apoptosis via the PI3K-AKT-mediated MDM2-p53 axis.
The Effects of Mitogen-activated Protein Kinase Signaling Pathways on Lipopolysaccharide-mediated Osteo/Odontogenic Differentiation of Stem Cells from the Apical Papilla.
Down-regulation of lncRNA OGFRP1 induces autophagy and growth inhibition by AKT/mTOR signaling pathway in HCAECs.
Investigating a chimeric anti-mouse PDGFRα antibody as a radiosensitizer in primary mouse sarcomas.
Antiviral activity of bone morphogenetic proteins and activins.
Decrease of GSK3β Ser-9 Phosphorylation Induced Osteoblast Apoptosis in Rat Osteoarthritis Model.
Acetylation of AGO2 promotes cancer progression by increasing oncogenic miR-19b biogenesis.
Lipopolysaccharide from Escherichia coli stimulates osteogenic differentiation of human periodontal ligament stem cells through Wnt/β-catenin-induced TAZ elevation.
Drastic induction of MMP-7 by cortisol in the human amnion: implications for membrane rupture at parturition.
Bisphenol A exposure alters placentation and causes preeclampsia-like features in pregnant mice involved in reprogramming of DNA methylation of WNT2.
PPPDE1 promotes hepatocellular carcinoma development by negatively regulate p53 and apoptosis.
Otx2 enhances transdifferentiation of Müller cells-derived retinal stem cells into photoreceptor-like cells.
Phorbol esters induce PLVAP expression via VEGF and additional secreted molecules in MEK1-dependent and p38, JNK and PI3K/Akt-independent manner.
Nucleoporin 107 facilitates the nuclear export of Scn5a mRNA to regulate cardiac bioelectricity.
Glucose Signaling Is Connected to Chromosome Segregation Through Protein Kinase A Phosphorylation of the Dam1 Kinetochore Subunit in Saccharomyces cerevisiae.
Endogenous cholesterol ester hydroperoxides modulate cholesterol levels and inhibit cholesterol uptake in hepatocytes and macrophages.
Proteomic Profiling of LPS-Induced Macrophage-Derived Exosomes Indicates Their Involvement in Acute Liver Injury.
miR-140-5p inhibits cell proliferation and invasion in colorectal carcinoma by targeting SOX4.
miR-7-5p inhibits cell migration and invasion in glioblastoma through targeting SATB1.
Ebselen protects rat hearts against myocardial ischemia-reperfusion injury.
Motor Neuron Abnormalities Correlate with Impaired Movement in Zebrafish that Express Mutant Superoxide Dismutase 1.
Doxorubicin conjugated with nanodiamonds and in free form commit glioblastoma cells to heterodromous fates.
Coupling function of cyclin-dependent kinase 2 and Septin2 in the promotion of hepatocellular carcinoma.
MiR-23a-3p acts as an oncogene and potential prognostic biomarker by targeting PNRC2 in RCC.
Long non-coding RNA SNHG6 enhances cell proliferation, migration and invasion by regulating miR-26a-5p/MAPK6 in breast cancer.
Noradrenergic depletion causes sex specific alterations in the endocannabinoid system in the Murine prefrontal cortex.
Combined Single-Cell Profiling of lncRNAs and Functional Screening Reveals that H19 Is Pivotal for Embryonic Hematopoietic Stem Cell Development.
SNHG1 promotes malignant biological behaviors of glioma cells via microRNA-154-5p/miR-376b-3p- FOXP2- KDM5B participating positive feedback loop.
Increased expression of thymic stromal lymphopoietin receptor in a rat model of middle cerebral artery occlusion.
Heterozygous Tbk1 loss has opposing effects in early and late stages of ALS in mice.
LPCAT1 promotes brain metastasis of lung adenocarcinoma by up-regulating PI3K/AKT/MYC pathway.
High-fat and high-glucose microenvironment decreases Runx2 and TAZ expression and inhibits bone regeneration in the mouse.
Novel metabolic disorders in skeletal muscle of Lipodystrophic Bscl2/Seipin deficient mice.
Curcumae Radix Extract Decreases Mammary Tumor-Derived Lung Metastasis via Suppression of C-C Chemokine Receptor Type 7 Expression.
Involvement of serum amyloid A1 in the rupture of fetal membranes through induction of collagen I degradation.
NLRC3 inhibits MCT-induced pulmonary hypertension in rats via attenuating PI3K activation.
Long non-coding RNA FAM84B-AS promotes resistance of gastric cancer to platinum drugs through inhibition of FAM84B expression.
Ankyrin-G regulated epithelial phenotype is required for mouse lens morphogenesis and growth.
Fragment-based drug discovery of triazole inhibitors to block PDEδ-RAS protein-protein interaction.
Host HDAC4 regulates the antiviral response by inhibiting the phosphorylation of IRF3.
MiR-26b suppresses hepatocellular carcinoma development by negatively regulating ZNRD1 and Wnt/β-catenin signaling.
Upregulation of CYP2E1 expression causes oxidative damage induced by 2-chloroethanol in primary cultured rat astrocytes.
Bioactive molecule Icariin inhibited proliferation while enhanced apoptosis and autophagy of rat airway smooth muscle cells in vitro.
Upregulated Expression of CUX1 Correlates with Poor Prognosis in Glioma Patients: a Bioinformatic Analysis.
Molecular mechanism of Bisphenol A on androgen receptor antagonism.
miR-124 ameliorates depressive-like behavior by targeting STAT3 to regulate microglial activation.
Ribociclib (LEE011) suppresses cell proliferation and induces apoptosis of MDA-MB-231 by inhibiting CDK4/6-cyclin D-Rb-E2F pathway.
Cancer cell membrane cloaking nanoparticles for targeted co-delivery of doxorubicin and PD-L1 siRNA.
Palmitoylome profiling indicates that androgens regulate the palmitoylation of α‑tubulin in prostate cancer‑derived LNCaP cells and supernatants.
Intrathecal injection of dexmedetomidine ameliorates chronic neuropathic pain via the modulation of MPK3/ERK1/2 in a mouse model of chronic neuropathic pain.
Mebendazole elicits potent antimyeloma activity by inhibiting the USP5/c-Maf axis.
Epigenetic regulation of TIMP1 expression by 8-oxoguanine DNA glycosylase-1 binding to DNA:RNA hybrid.
Silencing ubiquitin-conjugating enzyme 2C inhibits proliferation and epithelial-mesenchymal transition in pancreatic ductal adenocarcinoma.
Rotenone protects against β-cell apoptosis and attenuates type 1 diabetes mellitus.
STRIP2 silencing inhibits vascular smooth muscle cell proliferation and migration via P38-AKT-MMP-2 signaling pathway.
HOXC13-AS promotes breast cancer cell growth through regulating miR-497-5p/PTEN axis.
Integrated analysis of transcriptome data revealed MMP3 and MMP13 as critical genes in anaplastic thyroid cancer progression.
Critical roles of PI3K/Akt/NF‑κB survival axis in angiotensin II‑induced podocyte injury.
PTEN-knockdown disrupts the morphology, growth pattern and function of Nthy-Ori 3-1 cells by downregulating PAX8 expression.
Receptor tyrosine kinase expression in high-grade gliomas before and after chemoradiotherapy.
Caffeic acid reduces A53T α-synuclein by activating JNK/Bcl-2-mediated autophagy in vitro and improves behaviour and protects dopaminergic neurons in a mouse model of Parkinson's disease.
Identification of viral SIM-SUMO2-interaction inhibitors for treating primary effusion lymphoma.
Genetic ablation and pharmacological inhibition of immunosubunit β5i attenuates cardiac remodeling in deoxycorticosterone-acetate (DOCA)-salt hypertensive mice.
16 T high static magnetic field inhibits receptor activator of nuclear factor kappa-Β ligand-induced osteoclast differentiation by regulating iron metabolism in Raw264.7 cells.
Snail2 induced E-cadherin suppression and metastasis in lung carcinoma facilitated by G9a and HDACs.
Platelet endothelial aggregation receptor-1 regulates bovine muscle satellite cell migration and differentiation via integrin beta-1 and focal adhesion kinase.
Down-regulated long non-coding RNA PVT1 contributes to gestational diabetes mellitus and preeclampsia via regulation of human trophoblast cells.
Epigallocatechin-3-gallate inhibits tumor angiogenesis: involvement of endoglin/Smad1 signaling in human umbilical vein endothelium cells.
Ferulic acid increases intestinal Lactobacillus and improves cardiac function in TAC mice.
Endocytic degradation of ErbB2 mediates the effectiveness of neratinib in the suppression of ErbB2-positive ovarian cancer.
Forkhead box C1 promotes metastasis and invasion of non-small cell lung cancer by binding directly to the lysyl oxidase promoter.
Dietary Antioxidant Trans-Cinnamaldehyde Reduced Visfatin-Induced Breast Cancer Progression: In Vivo and In Vitro Study.
Rice Protein Exerts Anti-Inflammatory Effect in Growing and Adult Rats via Suppressing NF-κB Pathway.
Role of linc00174/miR-138-5p (miR-150-5p)/FOSL2 Feedback Loop on Regulating the Blood-Tumor Barrier Permeability.
Grape Seed Proanthocyanidins Induce Autophagy and Modulate Survivin in HepG2 Cells and Inhibit Xenograft Tumor Growth in Vivo.
NOS1 inhibits the interferon response of cancer cells by S-nitrosylation of HDAC2.
Astragaloside IV protects against diabetic nephropathy via activating eNOS in streptozotocin diabetes-induced rats.
Celastrol Inhibits Dopaminergic Neuronal Death of Parkinson's Disease through Activating Mitophagy.
Liver Soluble Epoxide Hydrolase Regulates Behavioral and Cellular Effects of Chronic Stress.
BMP10 preserves cardiac function through its dual activation of SMAD-mediated and STAT3-mediated pathways.
The regulatory effect of microRNA-21a-3p on the promotion of telocyte angiogenesis mediated by PI3K (p110α)/AKT/mTOR in LPS induced mice ARDS.
Antiviral activity of interleukin-11 as a response to porcine epidemic diarrhea virus infection.
Integrated Metabolomics and Network Pharmacology Strategy-Driven Active Traditional Chinese Medicine Ingredients Discovery for the Alleviation of Cisplatin Nephrotoxicity.
Hypothalamic paraventricular nucleus neurons activated by estrogen GPER1 receptors promote anti-inflammation effects in the early stage of colitis.
The Human Cytomegalovirus Nonstructural Glycoprotein UL148 Reorganizes the Endoplasmic Reticulum.
The Combination of Adipose-derived Schwann-like Cells and Acellular Nerve Allografts Promotes Sciatic Nerve Regeneration and Repair through the JAK2/STAT3 Signaling Pathway in Rats.
Silencing TTK expression inhibits the proliferation and progression of prostate cancer.
The exocyst complex regulates insulin-stimulated glucose uptake of skeletal muscle cells.
The focal adhesion scaffold protein Hic-5 regulates vimentin organization in fibroblasts.
Histone deacetylase 6 inhibitor ACY1215 offers a protective effect through the autophagy pathway in acute liver failure.
Paper/polymer composited microfluidic platform for screening cell viability and protein expression under a chemical gradient environment.
Downregulation of TMPRSS4 Enhances Triple-Negative Breast Cancer Cell Radiosensitivity Through Cell Cycle and Cell Apoptosis Process Impairment.
Reduced m6A modification predicts malignant phenotypes and augmented Wnt/PI3K-Akt signaling in gastric cancer.
RECQL5 plays an essential role in maintaining genome stability and viability of triple-negative breast cancer cells.
Dexmedetomidine alleviates LPS-induced apoptosis and inflammation in macrophages by eliminating damaged mitochondria via PINK1 mediated mitophagy.
Sulforaphane inhibits gastric cancer stem cells via suppressing sonic hedgehog pathway.
Angiogenic Factor AGGF1-Primed Endothelial Progenitor Cells Repair Vascular Defect in Diabetic Mice.
Steroid-Enriched Fraction of Achyranthes bidentata Protects Amyloid β Peptide 1-40-Induced Cognitive Dysfunction and Neuroinflammation in Rats.
Pyrroline-5-Carboxylate Reductase 1 Accelerates the Migration and Invasion of Nonsmall Cell Lung Cancer In Vitro.
Total flavonoids from sea buckthorn ameliorates lipopolysaccharide/cigarette smoke-induced airway inflammation.
FAT1, a direct transcriptional target of E2F1, suppresses cell proliferation, migration and invasion in esophageal squamous cell carcinoma.
Discovery of a Pathogenic Variant rs139379666 (p. P2974L) in ATM for Breast Cancer Risk in Chinese Populations.
Role of SNHG7-miR-653-5p-STAT2 feedback loop in regulating neuroblastoma progression.
Exosomes from tendon stem cells promote injury tendon healing through balancing synthesis and degradation of the tendon extracellular matrix.
MANF regulates splenic macrophage differentiation in mice.
Migrasome formation is mediated by assembly of micron-scale tetraspanin macrodomains.
Migrasomes provide regional cues for organ morphogenesis during zebrafish gastrulation.
Identification of COMMD1 as a novel lamin A binding partner.
E3 ligase Fbw7 participates in oxidative stress‑induced myocardial cell injury via interacting with Mcl‑1.
Roseburia intestinalis supernatant ameliorates colitis induced in mice by regulating the immune response.
Progranulin Promotes Bleomycin-Induced Skin Sclerosis by Enhancing Transforming Growth Factor-β/Smad3 Signaling through Up-Regulation of Transforming Growth Factor-β Type I Receptor.
Fibronectin regulates the self-renewal of rabbit limbal epithelial stem cells by stimulating the Wnt11/Fzd7/ROCK non-canonical Wnt pathway.
MicroRNA-2053 overexpression inhibits the development and progression of hepatocellular carcinoma.
Ursolic acid isolated from Isodon excisoides induces apoptosis and inhibits invasion of GBC-SD gallbladder carcinoma cells.
Inducible LGALS3BP/90K activates antiviral innate immune responses by targeting TRAF6 and TRAF3 complex.
Sesterterpene MHO7 suppresses breast cancer cells as a novel estrogen receptor degrader.
MicroRNA-128-3p aggravates doxorubicin-induced liver injury by promoting oxidative stress via targeting Sirtuin-1.
Inhibitor of growth 4 (ING4) inhibits hypoxia-induced EMT by decreasing HIF-1α and snail in HK2 cells.
STAT3-induced long noncoding RNA LINC00668 promotes migration and invasion of non-small cell lung cancer via the miR-193a/KLF7 axis.
Ablation of core fucosylation attenuates the signal transduction via T cell receptor to suppress the T cell development.
Vasorin stimulates malignant progression and angiogenesis in glioma.
CircAGFG1 sponges miR-203 to promote EMT and metastasis of non-small-cell lung cancer by upregulating ZNF281 expression.
Extracellular Vesicles from Albumin-Induced Tubular Epithelial Cells Promote the M1 Macrophage Phenotype by Targeting Klotho.
LncRNA MEG3 acts a biomarker and regulates cell functions by targeting ADAR1 in colorectal cancer.
Berberine prevents stress-induced gut inflammation and visceral hypersensitivity and reduces intestinal motility in rats.
Isoliquiritigenin Suppresses E2-Induced Uterine Leiomyoma Growth through the Modulation of Cell Death Program and the Repression of ECM Accumulation.
A novel role for NFIA in restoring radiosensitivity in radioresistant NSCLC cells by downregulating the AKT and ERK pathways.
Mitochondrial NOS1 suppresses apoptosis in colon cancer cells through increasing SIRT3 activity.
TFEB-driven autophagy potentiates TGF-β induced migration in pancreatic cancer cells.
Generation of Human Fatty Livers Using Custom-Engineered Induced Pluripotent Stem Cells with Modifiable SIRT1 Metabolism.
Simvastatin inhibits the proliferation of HL-60 clone 15- derived eosinophils by inducing the arrest of the cell cycle in the G1/S phase.
Endoplasmic reticulum stress and proteasome pathway involvement in human podocyte injury with a truncated COL4A3 mutation.
CBX8 promotes tumorigenesis and confers radioresistance in esophageal squamous cell carcinoma cells through targeting APAF1.
Ibuprofen inhibited migration of skeletal muscle cells in association with downregulation of p130cas and CrkII expressions.
EXT1, Regulated by MiR-665, Promotes Cell Apoptosis via ERK1/2 Signaling Pathway in Acute Lymphoblastic Leukemia.
Identification of Glyceraldehyde-3-Phosphate Dehydrogenase Gene as an Alternative Safe Harbor Locus in Pig Genome.
SIV-Mediated Synaptic Dysfunction Is Associated with an Increase in Synapsin Site 1 Phosphorylation and Impaired PP2A Activity.
Nelfinavir and lenalidomide/dexamethasone in patients with lenalidomide-refractory multiple myeloma. A phase I/II Trial (SAKK 39/10).
Anti-high mobility group box-1 antibody attenuated vascular smooth muscle cell phenotypic switching and vascular remodelling after subarachnoid haemorrhage in rats.
Topoisomerase inhibitors promote cancer cell motility via ROS-mediated activation of JAK2-STAT1-CXCL1 pathway.
CircRNA CBL.11 suppresses cell proliferation by sponging miR-6778-5p in colorectal cancer.
Depletion of phosphatidylinositol 4-phosphate at the Golgi translocates K-Ras to mitochondria.
MiR-1197-3p regulates testosterone secretion in goat Leydig cells via targeting PPARGC1A.
CBX3/HP1γ promotes tumor proliferation and predicts poor survival in hepatocellular carcinoma.
Internalization Characterization of Si Nanorod with Camouflaged Cell Membrane Proteins Reveals ATXN2 as a Negative Regulator.
Combined Assembly and Targeted Integration of Multigene for Nitrogenase Biosynthetic Pathway in Saccharomyces cerevisiae.
CRABP2 regulates invasion and metastasis of breast cancer through hippo pathway dependent on ER status.
miR-504 suppresses mesenchymal phenotype of glioblastoma by directly targeting the FZD7-mediated Wnt-β-catenin pathway.
IMM-H007 improves heart function via reducing cardiac fibrosis.
The combination of lonafarnib and sorafenib induces cyclin D1 degradation via ATG3-mediated autophagic flux in hepatocellular carcinoma cells.
Induction of Fibroblast Senescence During Mouse Corneal Wound Healing.
Corneal Denervation Causes Epithelial Apoptosis Through Inhibiting NAD+ Biosynthesis.
p21-Activated kinase 3 promotes cancer stem cell phenotypes through activating the Akt-GSK3β-β-catenin signaling pathway in pancreatic cancer cells.
Retinol binding protein 4 mediates MEHP-induced glucometabolic abnormalities in HepG2 cells.
RUNX1 promotes tumour metastasis by activating the Wnt/β-catenin signalling pathway and EMT in colorectal cancer.
Roseburia intestinalis inhibits oncostatin M and maintains tight junction integrity in a murine model of acute experimental colitis.
Adaptive EGF expression sensitizes pancreatic cancer cells to ionizing radiation through activation of the cyclin D1/P53/PARP pathway.
Expression patterns of C1ql4 and its cell-adhesion GPCR Bai3 in the murine testis and functional roles in steroidogenesis.
Treatment with metformin prevents myocardial ischemia-reperfusion injury via STEAP4 signaling pathway.
Comparative localization of cystathionine beta synthases and cystathionine gamma lyase in canine, non-human primate and human retina.
Type III interferon-induced CBFβ inhibits HBV replication by hijacking HBx.
5-(3,4-Difluorophenyl)-3-(6-methylpyridin-3-yl)-1,2,4-oxadiazole (DDO-7263), a novel Nrf2 activator targeting brain tissue, protects against MPTP-induced subacute Parkinson's disease in mice by inhibiting the NLRP3 inflammasome and protects PC12 cells against oxidative stress.
Role of p53 mediated miR-23a/CXCL12 pathway in osteogenic differentiation of bone mesenchymal stem cells on nanostructured titanium surfaces.
Ribociclib, a selective cyclin D kinase 4/6 inhibitor, inhibits proliferation and induces apoptosis of human cervical cancer in vitro and in vivo.
Adjudin synergizes with paclitaxel and inhibits cell growth and metastasis by regulating the sirtuin 3-Forkhead box O3a axis in human small-cell lung cancer.
Oxytocin Receptor Antagonists, Atosiban and Nolasiban, Inhibit Prostaglandin F2α-induced Contractions and Inflammatory Responses in Human Myometrium.
GTSE1 is involved in breast cancer progression in p53 mutation-dependent manner.
HAMP Downregulation Contributes to Aggressive Hepatocellular Carcinoma via Mechanism Mediated by Cyclin4-Dependent Kinase-1/STAT3 Pathway.
TMEM30A deficiency in endothelial cells impairs cell proliferation and angiogenesis.
FOXO1-regulated lncRNA LINC01197 inhibits pancreatic adenocarcinoma cell proliferation by restraining Wnt/β-catenin signaling.
Numb inhibits epithelial-mesenchymal transition via RBP-Jκ-dependent Notch1/PTEN/FAK signaling pathway in tongue cancer.
YAP Aggravates Inflammatory Bowel Disease by Regulating M1/M2 Macrophage Polarization and Gut Microbial Homeostasis.
Crosstalk Between Connexin32 and Mitochondrial Apoptotic Signaling Pathway Plays a Pivotal Role in Renal Ischemia Reperfusion-Induced Acute Kidney Injury.
Stabilized Peptide HDAC Inhibitors Derived from HDAC1 Substrate H3K56 for the Treatment of Cancer Stem-Like Cells In Vivo.
Benzoxazine monomer derived carbon dots as a broad-spectrum agent to block viral infectivity.
Proteomic analysis of mouse ovaries during the prepubertal stages.
Activation of GPR40 produces mechanical antiallodynia via the spinal glial interleukin-10/β-endorphin pathway.
CDK4/6 inhibitor palbociclib enhances the effect of pyrotinib in HER2-positive breast cancer.
Mild thermotherapy and hyperbaric oxygen enhance sensitivity of TMZ/PSi nanoparticles via decreasing the stemness in glioma.
Exosomal ephrinA2 derived from serum as a potential biomarker for prostate cancer.
P21-activated kinase 7 (PAK7) interacts with and activates Wnt/β-catenin signaling pathway in breast cancer.
TANK-Binding Kinase 1 (TBK1) Isoforms Negatively Regulate Type I Interferon Induction by Inhibiting TBK1-IRF3 Interaction and IRF3 Phosphorylation.
Core Fucosylation of the T Cell Receptor Is Required for T Cell Activation.
Fertility Enhancement but Premature Ovarian Failure in esr1-Deficient Female Zebrafish.
Bioinformatics Analysis Identifies p53 as a Candidate Prognostic Biomarker for Neuropathic Pain.
The Host Restriction Factor Interferon-Inducible Transmembrane Protein 3 Inhibits Vaccinia Virus Infection.
Tc17/IL-17A Up-Regulated the Expression of MMP-9 via NF-κB Pathway in Nasal Epithelial Cells of Patients With Chronic Rhinosinusitis.
Sesamin Protects the Femoral Head From Osteonecrosis by Inhibiting ROS-Induced Osteoblast Apoptosis in Rat Model.
Lactobacillus rhamnosus GR-1 Ameliorates Escherichia coli-Induced Activation of NLRP3 and NLRC4 Inflammasomes With Differential Requirement for ASC.
Effective Amelioration of Liver Fibrosis Through Lentiviral Vector Carrying Toxoplasma gondii gra15II in Murine Model.
MicroRNA-181a Functions as an Oncogene in Gastric Cancer by Targeting Caprin-1.
DEAD-Box Helicase 5 Interacts With Transcription Factor 12 and Promotes the Progression of Osteosarcoma by Stimulating Cell Cycle Progression.
Coagulation Factor X Regulated by CASC2c Recruited Macrophages and Induced M2 Polarization in Glioblastoma Multiforme.
Latent Membrane Protein 1 of Epstein-Barr Virus Promotes RIG-I Degradation Mediated by Proteasome Pathway.
Invalidation of Microsomal Prostaglandin E Synthase-1 (mPGES-1) Reduces Diet-Induced Low-Grade Inflammation and Adiposity.
Non-Hematopoietic MLKL Protects Against Salmonella Mucosal Infection by Enhancing Inflammasome Activation.
Evaluation of Oral Antiretroviral Drugs in Mice With Metabolic and Neurologic Complications.
Efficient delivery of nucleic acid molecules into skin by combined use of microneedle roller and flexible interdigitated electroporation array.
OVOL2 links stemness and metastasis via fine-tuning epithelial-mesenchymal transition in nasopharyngeal carcinoma.
S6K1 phosphorylation-dependent degradation of Mxi1 by β-Trcp ubiquitin ligase promotes Myc activation and radioresistance in lung cancer.
Long noncoding RNA CCAT2 is activated by E2F1 and exerts oncogenic properties by interacting with PTTG1 in pituitary adenomas.
Dengue Virus Infects Primary Human Hair Follicle Dermal Papilla Cells.
Neurodegeneration-associated FUS is a novel regulator of circadian gene expression.
Does the Genetic Feature of the Chinese Tree Shrew (Tupaia belangeri chinensis) Support Its Potential as a Viable Model for Alzheimer's Disease Research?
Huperzine A attenuates nonalcoholic fatty liver disease by regulating hepatocyte senescence and apoptosis: an in vitro study.
miRNA-1290 Promotes Aggressiveness in Pancreatic Ductal Adenocarcinoma by Targeting IKK1.
FGFR2 Promotes Gastric Cancer Progression by Inhibiting the Expression of Thrombospondin4 via PI3K-Akt-Mtor Pathway.
Activator Protein-2β Promotes Tumor Growth and Predicts Poor Prognosis in Breast Cancer.
HSP70/HSP90-Organizing Protein Contributes to Gastric Cancer Progression in an Autocrine Fashion and Predicts Poor Survival in Gastric Cancer.
Asiatic Acid (AA) Sensitizes Multidrug-Resistant Human Lung Adenocarcinoma A549/DDP Cells to Cisplatin (DDP) via Downregulation of P-Glycoprotein (MDR1) and Its Targets.
17β-Estradiol inhibits intervertebral disc degeneration by down-regulating MMP-3 and MMP-13 and up-regulating type II collagen in a rat model.
Neuroprotective Effects of Magnesium Lithospermate B against Subarachnoid Hemorrhage in Rats.
NR4A1 is Involved in Fibrogenesis in Ovarian Endometriosis.
Ethyl Pyruvate Attenuates CaCl2-Induced Tubular Epithelial Cell Injury by Inhibiting Autophagy and Inflammatory Responses.
Inhibition of Autophagy Attenuated Ethylene Glycol Induced Crystals Deposition and Renal Injury in a Rat Model of Nephrolithiasis.
Renal sympathetic denervation lowers arterial pressure in canines with obesity-induced hypertension by regulating GAD65 and AT1R expression in rostral ventrolateral medulla.
MST1 Suppression Reduces Early Brain Injury by Inhibiting the NF-κB/MMP-9 Pathway after Subarachnoid Hemorrhage in Mice.
Hypoxia Enhances Fusion of Oral Squamous Carcinoma Cells and Epithelial Cells Partly via the Epithelial-Mesenchymal Transition of Epithelial Cells.
Increased Autophagy Enhances the Resistance to Tumor Necrosis Factor-Alpha Treatment in Rheumatoid Arthritis Human Fibroblast-Like Synovial Cell.
Hydrogen Sulfide Alleviates Acute Myocardial Ischemia Injury by Modulating Autophagy and Inflammation Response under Oxidative Stress.
3-(1H-Benzo[d]imidazol-6-yl)-5-(4-fluorophenyl)-1,2,4-oxadiazole (DDO7232), a Novel Potent Nrf2/ARE Inducer, Ameliorates DSS-Induced Murine Colitis and Protects NCM460 Cells against Oxidative Stress via ERK1/2 Phosphorylation.
High Expression of ITGA3 Promotes Proliferation and Cell Cycle Progression and Indicates Poor Prognosis in Intrahepatic Cholangiocarcinoma.
Selenoprotein S Attenuates Tumor Necrosis Factor-α-Induced Dysfunction in Endothelial Cells.
RNF138 confers cisplatin resistance in gastric cancer cells via activating Chk1 signaling pathway.
MicroRNA-133b/EGFR axis regulates esophageal squamous cell carcinoma metastases by suppressing anoikis resistance and anchorage-independent growth.
Paraoxonase 3 is involved in the multi-drug resistance of esophageal cancer.
The lncRNA CCAT1 upregulates TGFβR1 via sponging miR-490-3p to promote TGFβ1-induced EMT of ovarian cancer cells.
Downregulation of MiR-203a Disinhibits Bmi1 and Promotes Growth and Proliferation of Keratinocytes in Cholesteatoma.
Amelioration of hepatic steatosis is associated with modulation of gut microbiota and suppression of hepatic miR-34a in Gynostemma pentaphylla (Thunb.) Makino treated mice.
Overexpression of Toll-like Receptor 4-linked Mitogen-activated Protein Kinase Signaling Contributes to Internalization of Escherichia coli in Sheep.
PARI functions as a new transcriptional target of FOXM1 involved in gastric cancer development.
Engagement of circular RNA HECW2 in the nonautophagic role of ATG5 implicated in the endothelial-mesenchymal transition.
Autosomal dominant retinitis pigmentosa-associated gene PRPF8 is essential for hypoxia-induced mitophagy through regulating ULK1 mRNA splicing.
Combined inhibition of autophagy and Nrf2 signaling augments bortezomib-induced apoptosis by increasing ROS production and ER stress in pancreatic cancer cells.
Dexmedetomidine attenuates the propofol-induced long-term neurotoxicity in the developing brain of rats by enhancing the PI3K/Akt signaling pathway.
Wenyang Huazhuo Tongluo formula inhibits fibrosis via suppressing Wnt/β-catenin signaling pathway in a Bleomycin-induced systemic sclerosis mouse model.
Notch inhibitor can attenuate apparent diffusion coefficient and improve neurological function through downregulating NOX2-ROS in severe traumatic brain injury.
Realgar, a traditional Chinese medicine, induces apoptosis of HPV16-positive cervical cells through a HPV16 E7-related pathway.
Zoledronate inhibits fibroblasts' proliferation and activation via targeting TGF-β signaling pathway.
Gestational Exposure to Particulate Matter 2.5 (PM2.5) Leads to Spatial Memory Dysfunction and Neurodevelopmental Impairment in Hippocampus of Mice Offspring.
EDIL3 depletion suppress epithelial-mesenchymal transition of lens epithelial cells via transforming growth factor β pathway.
Endothelial Monocyte-Activating Polypeptide-II Induces BNIP3-Mediated Mitophagy to Enhance Temozolomide Cytotoxicity of Glioma Stem Cells via Down-Regulating MiR-24-3p.
Brevilin A promotes oxidative stress and induces mitochondrial apoptosis in U87 glioblastoma cells.
MiR-429 Regulated by Endothelial Monocyte Activating Polypeptide-II (EMAP-II) Influences Blood-Tumor Barrier Permeability by Inhibiting the Expressions of ZO-1, Occludin and Claudin-5.
STAT3 induces colorectal carcinoma progression through a novel miR-572-MOAP-1 pathway.
Hypoxic Preconditioning Maintains GLT-1 Against Transient Global Cerebral Ischemia Through Upregulating Cx43 and Inhibiting c-Src.
Cosmosiin Increases ADAM10 Expression via Mechanisms Involving 5'UTR and PI3K Signaling.
Transcriptional Repression of p53 by PAX3 Contributes to Gliomagenesis and Differentiation of Glioma Stem Cells.
Characteristics of Sinus Fungus Ball: A Unique Form of Rhinosinusitis.
GPX3 suppresses tumor migration and invasion via the FAK/AKT pathway in esophageal squamous cell carcinoma.
NADH protect against radiation enteritis by enhancing autophagy and inhibiting inflammation through PI3K/AKT pathway.
Reduced selenium-binding protein 1 correlates with a poor prognosis in intrahepatic cholangiocarcinoma and promotes the cell epithelial-mesenchymal transition.
miR-125a-5p suppresses colorectal cancer progression by targeting VEGFA.
Non-coding RNA NEAT1/miR-214-3p contribute to doxorubicin resistance of urothelial bladder cancer preliminary through the Wnt/β-catenin pathway.
Inhibition of Cathepsins B Induces Neuroprotection Against Secondary Degeneration in Ipsilateral Substantia Nigra After Focal Cortical Infarction in Adult Male Rats.
The transcription factor C/EBP α controls the role of cystatin F during the differentiation of monocytes to macrophages.
Comparative proteomics reveals the neurotoxicity mechanism of ER stressors tunicamycin and dithiothreitol.
Gemcitabine induces apoptosis and autophagy via the AMPK/mTOR signaling pathway in pancreatic cancer cells.
Sex differences in the effect of cannabinoid type 1 receptor deletion on locus coeruleus-norepinephrine neurons and corticotropin releasing factor-mediated responses.
The suppressive effect of soluble Klotho on fibroblastic growth factor 23 synthesis in UMR-106 osteoblast-like cells.
Downregulation of TRIM58 expression is associated with a poor patient outcome and enhances colorectal cancer cell invasion.
Interferon Gamma Inhibits CXCL8-Induced Proliferation and Migration of Pancreatic Cancer BxPC-3 Cell Line via a RhoGDI2/Rac1/NF-κB Signaling Pathway.
Selective Actionable and Druggable Protein Kinases Drive the Progression of Neuroendocrine Prostate Cancer.
Activation of STAT3 and Bcl-2 and reduction of reactive oxygen species (ROS) promote radioresistance in breast cancer and overcome of radioresistance with niclosamide.
IL-6 increases podocyte motility via MLC-mediated focal adhesion impairment and cytoskeleton disassembly.
Epigenetic regulation of megakaryocytic and erythroid differentiation by PHF2 histone demethylase.
The oncogenic potentials and diagnostic significance of long non-coding RNA LINC00310 in breast cancer.
Stromal expression of JNK1 and VDR is associated with the prognosis of esophageal squamous cell carcinoma.
Protein arginine methyltransferase 5-mediated epigenetic silencing of IRX1 contributes to tumorigenicity and metastasis of gastric cancer.
UNBS5162 inhibits proliferation of human melanoma cells by inducing apoptosis via the PI3K/Akt pathway.
Adenoviral vector-induced silencing of RGMa attenuates blood-brain barrier dysfunction in a rat model of MCAO/reperfusion.
Role of hepatoma-derived growth factor in promoting de novo lipogenesis and tumorigenesis in hepatocellular carcinoma.
Long noncoding RNA LINC00460 targets miR-539/MMP-9 to promote meningioma progression and metastasis.
USP4 positively regulates RLR-induced NF-κB activation by targeting TRAF6 for K48-linked deubiquitination and inhibits enterovirus 71 replication.
FOXC1 induces cancer stem cell-like properties through upregulation of beta-catenin in NSCLC.
De Novo Mutations of CCNK Cause a Syndromic Neurodevelopmental Disorder with Distinctive Facial Dysmorphism.
LINC00470 Coordinates the Epigenetic Regulation of ELFN2 to Distract GBM Cell Autophagy.
Cationic Polymeric Nanoparticle Delivering CCR2 siRNA to Inflammatory Monocytes for Tumor Microenvironment Modification and Cancer Therapy.
A new meroterpenoid functions as an anti-tumor agent in hepatoma cells by downregulating mTOR activation and inhibiting EMT.
Long noncoding RNA MIR31HG inhibits hepatocellular carcinoma proliferation and metastasis by sponging microRNA-575 to modulate ST7L expression.
Covalent inhibitors of EGFR family protein kinases induce degradation of human Tribbles 2 (TRIB2) pseudokinase in cancer cells.
Distinct multilevel misregulations of Parkin and PINK1 revealed in cell and animal models of TDP-43 proteinopathy.
Targeting Epigenetic Crosstalk as a Therapeutic Strategy for EZH2-Aberrant Solid Tumors.
Anti-breast-Cancer Activity Exerted by β-Sitosterol-d-glucoside from Sweet Potato via Upregulation of MicroRNA-10a and via the PI3K-Akt Signaling Pathway.
Postinfarction Hearts Are Protected by Premature Senescent Cardiomyocytes Via GATA 4-Dependent CCN 1 Secretion.
IL-13 and IL-13Rα1 are overexpressed in extranodal natural killer/T cell lymphoma and mediate tumor cell proliferation.
Non-canonical NF-κB Antagonizes STING Sensor-Mediated DNA Sensing in Radiotherapy.
Mesenchymal stem cells alleviate experimental autoimmune cholangitis through immunosuppression and cytoprotective function mediated by galectin-9.
TPC2 mediates autophagy progression and extracellular vesicle secretion in cancer cells.
Rab7 empowers renal tubular epithelial cells with autophagy-mediated protection against albumin-induced injury.
Interaction of estrogen receptor β5 and interleukin 6 receptor in the progression of non-small cell lung cancer.
Human Cytomegalovirus Immediate Early 1 Protein Causes Loss of SOX2 from Neural Progenitor Cells by Trapping Unphosphorylated STAT3 in the Nucleus.
The developmental transcription factor IRF6 attenuates ABCG2 gene expression and distinctively reverses stemness phenotype in nasopharyngeal carcinoma.
Spinal interleukin-10 produces antinociception in neuropathy through microglial β-endorphin expression, separated from antineuroinflammation.
MALAT1 promotes the colorectal cancer malignancy by increasing DCP1A expression and miR203 downregulation.
MiR-616-3p modulates cell proliferation and migration through targeting tissue factor pathway inhibitor 2 in preeclampsia.
The effects of HAP and macrophage cells to the expression of inflammatory factors and apoptosis in HK-2 cells of vitro co-cultured system.
Effects of NMDAR Antagonist on the Regulation of P-MARCKS Protein to Aβ1-42 Oligomers Induced Neurotoxicity.
GPR40 modulates epileptic seizure and NMDA receptor function.
Erythropoietin-producing hepatocellular A7 triggering ovulation indicates a potential beneficial role for polycystic ovary syndrome.
SIRT5 deacylates metabolism-related proteins and attenuates hepatic steatosis in ob/ob mice.
Histone Deacetylase 3 Inhibitor Suppresses Hepatitis C Virus Replication by Regulating Apo-A1 and LEAP-1 Expression.
Histone deacetylase inhibitor suberoylanilide hydroxamic acid alleviates liver fibrosis by suppressing the transforming growth factor-β1 signal pathway.
Study on the expression of p53 and MMP-2 in patients with lung cancer after interventional therapy.
Subarachnoid hemorrhage enhances the expression of TDP-43 in the brain of experimental rats and human subjects.
Genistein sensitizes glioblastoma cells to carbon ions via inhibiting DNA-PKcs phosphorylation and subsequently repressing NHEJ and delaying HR repair pathways.
MicroRNA-23a-5p promotes atherosclerotic plaque progression and vulnerability by repressing ATP-binding cassette transporter A1/G1 in macrophages.
Long non-coding RNA LINC00222 regulates GSK3β activity and promotes cell apoptosis in lung adenocarcinoma.
MicroRNA-139-3p regulates osteoblast differentiation and apoptosis by targeting ELK1 and interacting with long noncoding RNA ODSM.
The effects of lncRNA MALAT1 on proliferation, invasion and migration in colorectal cancer through regulating SOX9.
Apigenin suppresses PD-L1 expression in melanoma and host dendritic cells to elicit synergistic therapeutic effects.
Salvianolic Acid B-Alleviated Angiotensin II Induces Cardiac Fibrosis by Suppressing NF-κB Pathway In Vitro.
MicroRNA-9 modified bone marrow-derived mesenchymal stem cells (BMSCs) repair severe acute pancreatitis (SAP) via inducing angiogenesis in rats.
Up-regulated miR-133a orchestrates epithelial-mesenchymal transition of airway epithelial cells.
Neuroinflammation is induced by tongue-instilled ZnO nanoparticles via the Ca2+-dependent NF-κB and MAPK pathways.
Enhanced anti-obesity effects of bacterial cellulose combined with konjac glucomannan in high-fat diet-fed C57BL/6J mice.
Immune Activation of RAW264.7 Macrophages by Low Molecular Weight Fucoidan Extracted from New Zealand Undaria pinnatifida.
Cd induces G2/M cell cycle arrest by up-regulating miR-133b via directly targeting PPP2R2D in L02 hepatocytes.
Biased antagonism of CXCR4 avoids antagonist tolerance.
GAPDH rs1136666 SNP indicates a high risk of Parkinson's disease.
PARP1 interacts with STAT3 and retains active phosphorylated-STAT3 in nucleus during pathological myocardial hypertrophy.
The Age-dependent Elevation of miR-335-3p Leads to Reduced Cholesterol and Impaired Memory in Brain.
Identification of the UBA2-WTIP fusion gene in acute myeloid leukemia.
Role of p62/SQSTM1 in lipopolysaccharide (LPS)-induced mucus hypersecretion in bronchial epithelial cells.
Bowman‒Birk Inhibitor Suppresses Herpes Simplex Virus Type 2 Infection of Human Cervical Epithelial Cells.
Mechanism of piR-DQ590027/MIR17HG regulating the permeability of glioma conditioned normal BBB.
Isopsoralen Enhanced Osteogenesis by Targeting AhR/ERα.
Deleting MyD88 signaling in myeloid cells promotes development of adenocarcinomas of the colon.
Alantolactone induces apoptosis and improves chemosensitivity of pancreatic cancer cells by impairment of autophagy-lysosome pathway via targeting TFEB.
Regulation of osteogenesis by micro/nano hierarchical titanium surfaces through a Rock-Wnt5a feedback loop.
The protective effect of melatonin on brain ischemia and reperfusion in rats and humans: In vivo assessment and a randomized controlled trial.
The sialyltransferase ST3Gal3 facilitates the receptivity of the uterine endometrium in vitro and in vivo.
RNA interference of long noncoding RNA HOTAIR suppresses autophagy and promotes apoptosis and sensitivity to cisplatin in oral squamous cell carcinoma.
HMGB1 knock-down promoting tumor cells viability and arrest pro-apoptotic proteins via Stat3/NFκB in HepG2 cells.
KLF5 promotes the tumorigenesis and metastatic potential of thyroid cancer cells through the NF-κB signaling pathway.
Microtubule associated protein 4 phosphorylation leads to pathological cardiac remodeling in mice.
METTL3-mediated N6-methyladenosine mRNA modification enhances long-term memory consolidation.
miR-153 inhibits the migration and the tube formation of endothelial cells by blocking the paracrine of angiopoietin 1 in breast cancer cells.
Silencing of rhomboid domain containing 1 to inhibit the metastasis of human breast cancer cells in vitro.
Deficiency in augmenter of liver regeneration accelerates liver fibrosis by promoting migration of hepatic stellate cell.
Boron Affects the Development of the Kidney Through Modulation of Apoptosis, Antioxidant Capacity, and Nrf2 Pathway in the African Ostrich Chicks.
Cantharidin inhibits melanoma cell proliferation via the miR‑21‑mediated PTEN pathway.
Protective effects of α‑2‑macroglobulin on human bone marrow mesenchymal stem cells in radiation injury.
Hepatitis B virus X protein promotes epithelial-mesenchymal transition and metastasis in hepatocellular carcinoma cell line HCCLM3 by targeting HMGA2.
METTL3 promotes ovarian carcinoma growth and invasion through the regulation of AXL translation and epithelial to mesenchymal transition.
Blocking LINC00152 suppresses glioblastoma malignancy by impairing mesenchymal phenotype through the miR-612/AKT2/NF-κB pathway.
Activation of α7 nicotinic acetylcholine receptor alleviates Aβ1-42-induced neurotoxicity via downregulation of p38 and JNK MAPK signaling pathways.
Pathological cyclic strain promotes proliferation of vascular smooth muscle cells via the ACTH/ERK/STAT3 pathway.
Toll-like receptor 4 shRNA attenuates lipopolysaccharide-induced epithelial-mesenchymal transition of intrahepatic biliary epithelial cells in rats.
miR-146b promotes cell proliferation and increases chemosensitivity, but attenuates cell migration and invasion via FBXL10 in ovarian cancer.
Evaluation of a Potential Clinical Significant Drug-Drug Interaction between Digoxin and Bupropion in Cynomolgus Monkeys.
Breed Differences in Pig Liver Esterase (PLE) between Tongcheng (Chinese Local Breed) and Large White Pigs.
Synergetic and Antagonistic Molecular Effects Mediated by the Feedback Loop of p53 and JNK between Saikosaponin D and SP600125 on Lung Cancer A549 Cells.
Expression of DEC2 enhances chemosensitivity by inhibiting STAT5A in gastric cancer.
Vasculogenic mimicry formation in EBV-associated epithelial malignancies.
Abnormally elevated USP37 expression in breast cancer stem cells regulates stemness, epithelial-mesenchymal transition and cisplatin sensitivity.
The Mitochondrial Apoptotic Effectors BAX/BAK Activate Caspase-3 and -7 to Trigger NLRP3 Inflammasome and Caspase-8 Driven IL-1β Activation.
Aspergillus fumigatus phospholipase D may enhance reactive oxygen species production by accumulation of histone deacetylase 6.
Tetrachlorobenzoquinone-Induced Nrf2 Confers Neuron-like PC12 Cells Resistance to Endoplasmic Reticulum Stress via Regulating Glutathione Synthesis and Protein Thiol Homeostasis.
PJA1 Coordinates with the SMC5/6 Complex To Restrict DNA Viruses and Episomal Genes in an Interferon-Independent Manner.
CHCHD2 accumulates in distressed mitochondria and facilitates oligomerization of CHCHD10.
Hemopexin reduces blood-brain barrier injury and protects synaptic plasticity in cerebral ischemic rats by promoting EPCs through the HO-1 pathway.
Tannic acid directly targets pyruvate kinase isoenzyme M2 to attenuate colon cancer cell proliferation.
Upregulation of circ-UBAP2 predicts poor prognosis and promotes triple-negative breast cancer progression through the miR-661/MTA1 pathway.
Astragaloside exerts anti-photoaging effects in UVB-induced premature senescence of rat dermal fibroblasts through enhanced autophagy.
Expression of programmed cell death protein 1 (PD-1) and indoleamine 2,3-dioxygenase (IDO) in the tumor microenvironment and in tumor-draining lymph nodes of breast cancer.
Progranulin promotes lymphangiogenesis through VEGF-C and is an independent risk factor in human esophageal cancers.
MicroRNA-181c promotes Th17 cell differentiation and mediates experimental autoimmune encephalomyelitis.
Resveratrol Improves Muscle Atrophy by Modulating Mitochondrial Quality Control in STZ-Induced Diabetic Mice.
Follicle-stimulating hormone enhances hepatic gluconeogenesis by GRK2-mediated AMPK hyperphosphorylation at Ser485 in mice.
CEACAM1 resists hypoxia-induced inhibition of tube formation of human dermal lymphatic endothelial cells.
Ultrasound Irradiation Combined with Hepatocyte Growth Factor Accelerate the Hepatic Differentiation of Human Bone Marrow Mesenchymal Stem Cells.
Effect of placental sex hormone-binding globulin single nucleotide polymorphism rs6259 on protein and function in gestational diabetes mellitus.
Identification of Functional Thyroid Stimulating Hormone Receptor and TSHR Gene Mutations in Hepatocellular Carcinoma.
The E3 ubiquitin ligase Triad1 influences development of Mll-Ell-induced acute myeloid leukemia.
LncRNA-PVT1 promotes pancreatic cancer cells proliferation and migration through acting as a molecular sponge to regulate miR-448.
Antagonism of cortistatin against cyclosporine-induced apoptosis in rat myocardial cells and its effect on myocardial apoptosis gene expression.
PVT1 regulates the malignant behaviors of human glioma cells by targeting miR-190a-5p and miR-488-3p.
FTO promotes SREBP1c maturation and enhances CIDEC transcription during lipid accumulation in HepG2 cells.
Targeting Polo-like Kinase 1 by a Novel Pyrrole-Imidazole Polyamide-Hoechst Conjugate Suppresses Tumor Growth In Vivo.
Liraglutide improves hepatic insulin resistance via the canonical Wnt signaling pathway.
Local intra‑articular injection of vascular endothelial growth factor accelerates articular cartilage degeneration in rat osteoarthritis model.
Cantharidin suppresses cell growth and migration, and activates autophagy in human non-small cell lung cancer cells.
M2-specific reduction of CD1d switches NKT cell-mediated immune responses and triggers metaflammation in adipose tissue.
Cardioprotection of CAPE-oNO2 against myocardial ischemia/reperfusion induced ROS generation via regulating the SIRT1/eNOS/NF-κB pathway in vivo and in vitro.
The glucagon-like peptide-1 (GLP-1) analog liraglutide attenuates renal fibrosis.
Diallyl Trisulfide inhibits breast cancer stem cells via suppression of Wnt/β-catenin pathway.
Activation of AMPK by simvastatin inhibited breast tumor angiogenesis via impeding HIF-1α-induced pro-angiogenic factor.
Chromosome Segregation Is Biased by Kinetochore Size.
CysLTR1 Blockage Ameliorates Liver Injury Caused by Aluminum-Overload via PI3K/AKT/mTOR-Mediated Autophagy Activation in Vivo and in Vitro.
Interleukin-23 promotes the migration and invasion of gastric cancer cells by inducing epithelial-to-mesenchymal transition via the STAT3 pathway.
Dysregulation of tristetraprolin and human antigen R promotes gastric cancer progressions partly by upregulation of the high-mobility group box 1.
The Novel miRNA N-72 Regulates EGF-Induced Migration of Human Amnion Mesenchymal Stem Cells by Targeting MMP2.
Resting T cells are hypersensitive to DNA damage due to defective DNA repair pathway.
Dietary supplementation with ketoacids protects against CKD-induced oxidative damage and mitochondrial dysfunction in skeletal muscle of 5/6 nephrectomised rats.
Identification of Selective, Cell Active Inhibitors of Protein Arginine Methyltransferase 5 through Structure-Based Virtual Screening and Biological Assays.
MiR-29c reduces the cisplatin resistance of non-small cell lung cancer cells by negatively regulating the PI3K/Akt pathway.
Dexmedetomidine reduces ventilator-induced lung injury (VILI) by inhibiting Toll-like receptor 4 (TLR4)/nuclear factor (NF)-κB signaling pathway.
Apolipoprotein C1 promotes prostate cancer cell proliferation in vitro.
Long-term exposure to low-dose Haemophilus influenzae during allergic airway disease drives a steroid-resistant neutrophilic inflammation and promotes airway remodeling.
LGR5 promotes epithelial ovarian cancer proliferation, metastasis, and epithelial-mesenchymal transition through the Notch1 signaling pathway.
Rotenone ameliorates chronic renal injury caused by acute ischemia/reperfusion.
Single-Cell Analysis of the Impact of Host Cell Heterogeneity on Infection with Foot-and-Mouth Disease Virus.
Autophagic degradation of caveolin-1 promotes liver sinusoidal endothelial cells defenestration.
KIF4A facilitates cell proliferation via induction of p21-mediated cell cycle progression and promotes metastasis in colorectal cancer.
Dkk3 dependent transcriptional regulation controls age related skeletal muscle atrophy.
Inhibition of transient receptor potential melastatin 8 alleviates airway inflammation and remodeling in a murine model of asthma with cold air stimulus.
Rewiring of Glutamine Metabolism Is a Bioenergetic Adaptation of Human Cells with Mitochondrial DNA Mutations.
The Dopamine Receptor D3 Regulates Lipopolysaccharide-Induced Depressive-Like Behavior in Mice.
Glial fibrillary acidic protein promoter determines transgene expression in satellite glial cells following intraganglionic adeno-associated virus delivery in adult rats.
Periostin promotes migration, proliferation, and differentiation of human periodontal ligament mesenchymal stem cells.
Combination Treatment with Methylene Blue and Hypothermia in Global Cerebral Ischemia.
Role of the hippocampal 5-HT1A receptor-mediated cAMP/PKA signalling pathway in sevoflurane-induced cognitivedysfunction in aged rats.
Baicalin protects H9c2 cardiomyocytes against hypoxia/reoxygenation-induced apoptosis and oxidative stress through activation of mitochondrial aldehyde dehydrogenase 2.
Analysis of the oncogene BRAF mutation and the correlation of the expression of wild-type BRAF and CREB1 in endometriosis.
Tumor-suppressive miRNA-135a inhibits breast cancer cell proliferation by targeting ELK1 and ELK3 oncogenes.
miR-141 inhibits prostatic cancer cell proliferation and migration, and induces cell apoptosis via targeting of RUNX1.
TAp63 is correlated with chronic inflammation in patients with newly diagnosed type 2 diabetes mellitus.
Identification of a novel compound targeting the nuclear export of influenza A virus nucleoprotein.
Analysis of the association of the expression of KiSS-1 in colorectal cancer tissues with the pathology and prognosis.
miR-98 inhibits cell proliferation and induces cell apoptosis by targeting MAPK6 in HUVECs.
Type I IFN augments IL-27-dependent TRIM25 expression to inhibit HBV replication.
MAD2L2 inhibits colorectal cancer growth by promoting NCOA3 ubiquitination and degradation.
Protein kinase C epsilon mediates the inhibition of angiotensin II on the slowly activating delayed-rectifier potassium current through channel phosphorylation.
Lanthanum chloride impairs memory in rats by disturbing the glutamate-glutamine cycle and over-activating NMDA receptors.
The expression of the new epididymal luminal protein of PDZ domain containing 1 is decreased in asthenozoospermia.
MiR-134, epigenetically silenced in gliomas, could mitigate the malignant phenotype by targeting KRAS.
SFTS phlebovirus promotes LC3-II accumulation and nonstructural protein of SFTS phlebovirus co-localizes with autophagy proteins.
Inhibition of HIV early replication by the p53 and its downstream gene p21.
Overexpression of zinc-α2-glycoprotein suppressed seizures and seizure-related neuroflammation in pentylenetetrazol-kindled rats.
The transcriptional profiles and functional implications of long non-coding RNAs in the unfolded protein response.
Regulation by FSH of the dynamic expression of retinol-binding protein 4 in the mouse ovary.
Transmembrane E3 ligase RNF183 mediates ER stress-induced apoptosis by degrading Bcl-xL.
Pin1 mediates Aβ42-induced dendritic spine loss.
PIWIL1/piRNA-DQ593109 Regulates the Permeability of the Blood-Tumor Barrier via the MEG3/miR-330-5p/RUNX3 Axis.
circ-SHKBP1 Regulates the Angiogenesis of U87 Glioma-Exposed Endothelial Cells through miR-544a/FOXP1 and miR-379/FOXP2 Pathways.
Zc3h13 Regulates Nuclear RNA m6A Methylation and Mouse Embryonic Stem Cell Self-Renewal.
In vitro study of FUZ as a novel potential therapeutic target in non-small-cell lung cancer.
Cigarette smoke stimulates the stemness of renal cancer stem cells via Sonic Hedgehog pathway.
Structural Basis for the Inhibition of Host Gene Expression by Porcine Epidemic Diarrhea Virus nsp1.
LncRNA UCA1 attenuates autophagy-dependent cell death through blocking autophagic flux under arsenic stress.
Cell division cycle 7 is a potential therapeutic target in oral squamous cell carcinoma and is regulated by E2F1.
Propranolol prevents liver cirrhosis by inhibiting hepatic stellate cell activation mediated by the PDGFR/Akt pathway.
Setd7 and its contribution to Boron-induced bone regeneration in Boron-mesoporous bioactive glass scaffolds.
Clinical significance of combined detection of interleukin-6 and tumour markers in lung cancer.
Oestrogen receptor β5 and epidermal growth factor receptor synergistically promote lung cancer progression.
Mutant KRAS promotes liver metastasis of colorectal cancer, in part, by upregulating the MEK-Sp1-DNMT1-miR-137-YB-1-IGF-IR signaling pathway.
Sequestosome 1 protects esophageal squamous carcinoma cells from apoptosis via stabilizing SKP2 under serum starvation condition.
Abberent expression of NOR1 protein in tumor associated macrophages contributes to the development of DEN-induced hepatocellular carcinoma.
S1PR3 is essential for phosphorylated fingolimod to protect astrocytes against oxygen-glucose deprivation-induced neuroinflammation via inhibiting TLR2/4-NFκB signalling.
Correlation between autophagy levels in peripheral blood mononuclear cells and clinical parameters in patients with chronic obstructive pulmonary disease.
Osteogenesis potential of different titania nanotubes in oxidative stress microenvironment.
Protective effect of dioscin against doxorubicin-induced cardiotoxicity via adjusting microRNA-140-5p-mediated myocardial oxidative stress.
Downregulation of FOXP2 promotes breast cancer migration and invasion through TGFβ/SMAD signaling pathway.
Excessive endoplasmic reticulum stress and decreased neuroplasticity-associated proteins in prefrontal cortex of obese rats and the regulatory effects of aerobic exercise.
Cognitive-enhancing effect of polysaccharides from Flammulina velutipes on Alzheimer's disease by compatibilizing with ginsenosides.
Krüppel-like factor 4 promotes c-Met amplification-mediated gefitinib resistance in non-small-cell lung cancer.
Effects of cholecalciferol cholesterol emulsion on renal fibrosis and aquaporin 2 and 4 in mice with unilateral ureteral obstruction.
The natural compound GL22, isolated from Ganoderma mushrooms, suppresses tumor growth by altering lipid metabolism and triggering cell death.
Metformin ameliorates TGF-β1-induced osteoblastic differentiation of human aortic valve interstitial cells by inhibiting β-catenin signaling.
HEV ORF3 downregulates TLR7 to inhibit the generation of type I interferon via impairment of multiple signaling pathways.
Integrin αvβ3-associated DAAM1 is essential for collagen-induced invadopodia extension and cell haptotaxis in breast cancer cells.
Traditional Chinese medication Tongxinluo attenuates apoptosis in ox-LDL-stimulated macrophages by enhancing Beclin-1-induced autophagy.
Carbon monoxide-releasing molecule-3 protects against ischemic stroke by suppressing neuroinflammation and alleviating blood-brain barrier disruption.
4EHP-independent repression of endogenous mRNAs by the RNA-binding protein GIGYF2.
Deer thymosin beta 10 functions as a novel factor for angiogenesis and chondrogenesis during antler growth and regeneration.
Oxidative stress-mediated autophagic cell death participates in the neurotoxic effect on SH-SY5Y cells induced by excessive iodide.
SPG6 supports development of acute myeloid leukemia by regulating BMPR2-Smad-Bcl-2/Bcl-xl signaling.
PHF5A Epigenetically Inhibits Apoptosis to Promote Breast Cancer Progression.
RBM4 Modulates Radial Migration via Alternative Splicing of Dab1 during Cortex Development.
Reversal of reserpine-induced depression and cognitive disorder in zebrafish by sertraline and Traditional Chinese Medicine (TCM).
Exosomes released by hepatocarcinoma cells endow adipocytes with tumor-promoting properties.
Downregulation of HS6ST2 by miR-23b-3p enhances matrix degradation through p38 MAPK pathway in osteoarthritis.
BAI1 Suppresses Medulloblastoma Formation by Protecting p53 from Mdm2-Mediated Degradation.
miR-675 promotes odontogenic differentiation of human dental pulp cells by epigenetic regulation of DLX3.
Acetylation of oxidized base repair-initiating NEIL1 DNA glycosylase required for chromatin-bound repair complex formation in the human genome increases cellular resistance to oxidative stress.
HBeAg induces the expression of macrophage miR-155 to accelerate liver injury via promoting production of inflammatory cytokines.
Furin promotes dendritic morphogenesis and learning and memory in transgenic mice.
Farnesoid X receptor signaling activates the hepatic X-box binding protein 1 pathway in vitro and in mice.
Anti-fibrogenic Potential of Mesenchymal Stromal Cells in Treating Fibrosis in Crohn's Disease.
Glycyrrhizin ameliorates atopic dermatitis-like symptoms through inhibition of HMGB1.
LncRNA MT1DP Aggravates Cadmium-Induced Oxidative Stress by Repressing the Function of Nrf2 and is Dependent on Interaction with miR-365.
BCL11A Down-Regulation Induces γ-Globin in Human β-Thalassemia Major Erythroid Cells.
Programmed death ligand 1 promotes lymph node metastasis and glucose metabolism in cervical cancer by activating integrin β4/SNAI1/SIRT3 signaling pathway.
Estrogen-related receptor alpha is involved in Alzheimer's disease-like pathology.
The endosomal recycling of FgSnc1 by FgSnx41-FgSnx4 heterodimer is essential for polarized growth and pathogenicity in Fusarium graminearum.
Inhibition of Mitochondrial Fission Preserves Photoreceptors after Retinal Detachment.
Increased oxidative stress mediates the antitumor effect of PARP inhibition in ovarian cancer.
Sulforaphane attenuates microglia-mediated neuronal necroptosis through down-regulation of MAPK/NF-κB signaling pathways in LPS-activated BV-2 microglia.
Temporary inhibition of the plasminogen activator inhibits periosteal chondrogenesis and promotes periosteal osteogenesis during appendicular bone fracture healing.
BET bromodomain inhibitor JQ1 preferentially suppresses EBV-positive nasopharyngeal carcinoma cells partially through repressing c-Myc.
SET1A-Mediated Mono-Methylation at K342 Regulates YAP Activation by Blocking Its Nuclear Export and Promotes Tumorigenesis.
Naringenin exhibits the protective effect on cardiac hypertrophy via EETs-PPARs activation in streptozocin-induced diabetic mice.
The exon 19-deleted EGFR undergoes ubiquitylation-mediated endocytic degradation via dynamin activity-dependent and -independent mechanisms.
Ketamine differentially restores diverse alterations of neuroligins in brain regions in a rat model of neuropathic pain-induced depression.
Tristetraprolin Overexpression in Gastric Cancer Cells Suppresses PD-L1 Expression and Inhibits Tumor Progression by Enhancing Antitumor Immunity.
Circular RNA IARS (circ-IARS) secreted by pancreatic cancer cells and located within exosomes regulates endothelial monolayer permeability to promote tumor metastasis.
PEI-Coated Fe₃O₄ Nanoparticles Enable Efficient Delivery of Therapeutic siRNA Targeting REST into Glioblastoma Cells.
Imbalanced LIMK1 and LIMK2 expression leads to human colorectal cancer progression and metastasis via promoting β-catenin nuclear translocation.
17β-estradiol upregulates IL6 expression through the ERβ pathway to promote lung adenocarcinoma progression.
3-O-acetyl-11-keto-β-boswellic acid exerts anti-tumor effects in glioblastoma by arresting cell cycle at G2/M phase.
ZDHHC8 critically regulates seizure susceptibility in epilepsy.
FoxM1 repression during human aging leads to mitotic decline and aneuploidy-driven full senescence.
Long non-coding RNA PVT1 promotes malignancy in human endometrial carcinoma cells through negative regulation of miR-195-5p.
Comparison of the effects of selenomethionine and selenium-enriched yeast in the triple-transgenic mouse model of Alzheimer's disease.
Unique BIR domain sets determine inhibitor of apoptosis protein-driven cell death and NOD2 complex signal specificity.
Aspirin is Involved in the Cell Cycle Arrest, Apoptosis, Cell Migration, and Invasion of Oral Squamous Cell Carcinoma.
TNFRSF19 Inhibits TGFβ Signaling through Interaction with TGFβ Receptor Type I to Promote Tumorigenesis.
Protective effect of dioscin against thioacetamide-induced acute liver injury via FXR/AMPK signaling pathway in vivo.
Stachydrine ameliorates carbon tetrachloride-induced hepatic fibrosis by inhibiting inflammation, oxidative stress and regulating MMPs/TIMPs system in rats.
β-Arrestin-1 deficiency ameliorates renal interstitial fibrosis by blocking Wnt1/β-catenin signaling in mice.
Limb remote ischemia per-conditioning protects the heart against ischemia-reperfusion injury through the opioid system in rats.
Propofol attenuates myocardial ischemia reperfusion injury partly through inhibition of resident cardiac mast cell activation.
Vimentin is a crucial target for anti-metastasis therapy of nasopharyngeal carcinoma.
Knockdown of eukaryotic translation initiation factor 3 subunit D (eIF3D) inhibits proliferation of acute myeloid leukemia cells.
Proteasome inhibitor bortezomib is a novel therapeutic agent for focal radiation-induced osteoporosis.
Localization of endogenous amyloid-β to the coeruleo-cortical pathway: consequences of noradrenergic depletion.
Down-regulation of miR-10a-5p in synoviocytes contributes to TBX5-controlled joint inflammation.
IgE induces hypotension in asthma mice by down-regulating vascular NCX1 expression through activating MiR-212-5p.
Cell Cycle-Dependent Tumor Engraftment and Migration Are Enabled by Aurora-A.
Sphingomyelin synthase 2 overexpression promotes cisplatin-induced apoptosis of HepG2 cells.
PTEN-L promotes type I interferon responses and antiviral immunity.
20-HETE regulated PSMB5 expression via TGF-β/Smad signaling pathway.
Icariin, a flavonoid with anti-cancer effects, alleviated paclitaxel-induced neuropathic pain in a SIRT1-dependent manner.
Downregulation of N6-methyladenosine binding YTHDF2 protein mediated by miR-493-3p suppresses prostate cancer by elevating N6-methyladenosine levels.
Inhibition of insulin resistance by PGE1 via autophagy-dependent FGF21 pathway in diabetic nephropathy.
Genomic and Epigenomic Profiling of High-Risk Intestinal Metaplasia Reveals Molecular Determinants of Progression to Gastric Cancer.
Neutrophil extracellular traps contribute to the pathogenesis of acid-aspiration-induced ALI/ARDS.
Protective Effects of Leukemia Inhibitory Factor on Retinal Vasculature and Cells in Streptozotocin-induced Diabetic Mice.
Antidiabetic activities of entagenic acid in type 2 diabetic db/db mice and L6 myotubes via AMPK/GLUT4 pathway.
LncRNA LOC730101 promotes osteosarcoma cell survival under energy stress.
Hydrogen-water ameliorates radiation-induced gastrointestinal toxicity via MyD88's effects on the gut microbiota.
Gentiopicroside ameliorates bleomycin-induced pulmonary fibrosis in mice via inhibiting inflammatory and fibrotic process.
C-MYC and BCL-2 mediate YAP-regulated tumorigenesis in OSCC.
Comprehensive Genomic Characterization of RNA-Binding Proteins across Human Cancers.
The Potential Roles of the Apoptosis-Related Protein PDRG1 in Diapause Embryo Restarting of Artemia sinica.
SOCE induced calcium overload regulates autophagy in acute pancreatitis via calcineurin activation.
IcarisideII improves left ventricular remodeling in spontaneously hypertensive rats by inhibiting the ASK1-JNK/p38 signaling pathway.
FBXO2, a novel marker for metastasis in human gastric cancer.
SIRT3 prevents angiotensin II-induced renal tubular epithelial-mesenchymal transition by ameliorating oxidative stress and mitochondrial dysfunction.
Exosomes derived from imatinib-resistant chronic myeloid leukemia cells mediate a horizontal transfer of drug-resistant trait by delivering miR-365.
Co-expression analysis revealed PTCH1-3'UTR promoted cell migration and invasion by activating miR-101-3p/SLC39A6 axis in non-small cell lung cancer: implicating the novel function of PTCH1.
Inhibition of autophagy-attenuated calcium oxalate crystal-induced renal tubular epithelial cell injury in vivo and in vitro.
MicroRNA-200a confers chemoresistance by antagonizing TP53INP1 and YAP1 in human breast cancer.
Pharmacological Investigation of the Anti-Inflammation and Anti-Oxidation Activities of Diallyl Disulfide in a Rat Emphysema Model Induced by Cigarette Smoke Extract.
GBP3 promotes glioma cell proliferation via SQSTM1/p62-ERK1/2 axis.
Protein Kinase A/CREB Signaling Prevents Adriamycin-Induced Podocyte Apoptosis via Upregulation of Mitochondrial Respiratory Chain Complexes.
MiR-208a-3p aggravates autophagy through the PDCD4-ATG5 pathway in Ang II-induced H9c2 cardiomyoblasts.
The E3 ubiquitin ligase MuRF2 attenuates LPS-induced macrophage activation by inhibiting production of inflammatory cytokines and migration.
Exosomes From Adipose-Derived Stem Cells Attenuate Adipose Inflammation and Obesity Through Polarizing M2 Macrophages and Beiging in White Adipose Tissue.
Speckle-Type POZ Protein Down-Regulates Matrix Metalloproteinase 2 Expression via Sp1/PI3K/Akt Signaling Pathway in Colorectal Cancer.
Proteasome-mediated degradation of collagen III by cortisol in amnion fibroblasts.
Telbivudine attenuates UUO-induced renal fibrosis via TGF-β/Smad and NF-κB signaling.
Clinical significance of C/D box small nucleolar RNA U76 as an oncogene and a prognostic biomarker in hepatocellular carcinoma.
Fungal β-Glucan Activates the NLRP3 Inflammasome in Human Bronchial Epithelial Cells Through ROS Production.
NLRC5 deficiency ameliorates diabetic nephropathy through alleviating inflammation.
Coordinated transcription of ANRIL and P16 genes is silenced by P16 DNA methylation.
Ephrin receptor A2 is an epithelial cell receptor for Epstein-Barr virus entry.
Intrinsic antimicrobial properties of silk spun by genetically modified silkworm strains.
Recurrent ECSIT mutation encoding V140A triggers hyperinflammation and promotes hemophagocytic syndrome in extranodal NK/T cell lymphoma.
The long non-coding RNA PVT1 represses ANGPTL4 transcription through binding with EZH2 in trophoblast cell.
Quantitative proteomics study of host response to virulent and attenuated pseudorabies virus infection in mouse brain.
SATB2 suppresses non-small cell lung cancer invasiveness by G9a.
Propofol protects against endotoxin-induced myocardial injury by inhibiting NF-κB-mediated inflammation.
Annexin A10 contributes to chronic constrictive injury-induced pain through activating ERK1/2 signalling in rats.
Decreased expression of hepatic cytochrome P450 1A2 (CYP1A2) in a chronic intermittent hypoxia mouse model.
Fasudil increases temozolomide sensitivity and suppresses temozolomide-resistant glioma growth via inhibiting ROCK2/ABCG2.
Photosensitization of A2E triggers telomere dysfunction and accelerates retinal pigment epithelium senescence.
Nicotine promotes atherosclerosis via ROS-NLRP3-mediated endothelial cell pyroptosis.
Flavagline analog FL3 induces cell cycle arrest in urothelial carcinoma cell of the bladder by inhibiting the Akt/PHB interaction to activate the GADD45α pathway.
Silencing Ras-Related C3 Botulinum Toxin Substrate 1 Inhibits Growth and Migration of Hypopharyngeal Squamous Cell Carcinoma via the P38 Mitogen-Activated Protein Kinase Signaling Pathway.
N-oleoylethanolamide suppresses intimal hyperplasia after balloon injury in rats through AMPK/PPARα pathway.
Estrogen directly stimulates LHb expression at the pituitary level during puberty in female zebrafish.
Ginsenoside Rg3 sensitizes hypoxic lung cancer cells to cisplatin via blocking of NF-κB mediated epithelial-mesenchymal transition and stemness.
Comprehensive integrative analyses identify GLT8D1 and CSNK2B as schizophrenia risk genes.
Liver-specific deletion of TSHR inhibits hepatic lipid accumulation in mice.
PIM1 mediates epithelial-mesenchymal transition by targeting Smads and c-Myc in the nucleus and potentiates clear-cell renal-cell carcinoma oncogenesis.
High-fat Diet Mediates Anxiolytic-like Behaviors in a Time-dependent Manner Through the Regulation of SIRT1 in the Brain.
GRK5 functions as an oncogenic factor in non-small-cell lung cancer.
TRAF6 regulates EGF-induced cell transformation and cSCC malignant phenotype through CD147/EGFR.
Interferon-alpha enhances the antitumour activity of EGFR-targeted therapies by upregulating RIG-I in head and neck squamous cell carcinoma.
Upregulation of kinesin family member 4A enhanced cell proliferation via activation of Akt signaling and predicted a poor prognosis in hepatocellular carcinoma.
NIT1 suppresses tumour proliferation by activating the TGFβ1-Smad2/3 signalling pathway in colorectal cancer.
Molecular adaptations of adipose tissue to 6 weeks of morning fasting vs. daily breakfast consumption in lean and obese adults.
Hypoxia Activates Src and Promotes Endocytosis Which Decreases MMP-2 Activity and Aggravates Renal Interstitial Fibrosis.
hPMSC transplantation restoring ovarian function in premature ovarian failure mice is associated with change of Th17/Tc17 and Th17/Treg cell ratios through the PI3K/Akt signal pathway.
Polycystin-2 is an essential ion channel subunit in the primary cilium of the renal collecting duct epithelium.
MYL6B, a myosin light chain, promotes MDM2-mediated p53 degradation and drives HCC development.
MicroRNA-29a mitigation of toll-like receptor 2 and 4 signaling and alleviation of obstructive jaundice-induced fibrosis in mice.
Ursolic Acid Attenuates High Glucose-Mediated Mesangial Cell Injury by Inhibiting the Phosphatidylinositol 3-Kinase/Akt/Mammalian Target of Rapamycin (PI3K/Akt/mTOR) Signaling Pathway.
Overcoming STC2 mediated drug resistance through drug and gene co-delivery by PHB-PDMAEMA cationic polyester in liver cancer cells.
AF119895 regulates NXF3 expression to promote migration and invasion of hepatocellular carcinoma through an interaction with miR-6508-3p.
Bone marrow mesenchymal stromal cells alleviate brain white matter injury via the enhanced proliferation of oligodendrocyte progenitor cells in focal cerebral ischemic rats.
Truncated SALL1 Impedes Primary Cilia Function in Townes-Brocks Syndrome.
Novel synthetic 4-chlorobenzoyl berbamine inhibits c-Myc expression and induces apoptosis of diffuse large B cell lymphoma cells.
Quercetin ameliorates pulmonary fibrosis by inhibiting SphK1/S1P signaling.
Red nucleus interleukin-1β evokes tactile allodynia through activation of JAK/STAT3 and JNK signaling pathways.
Apolipoprotein E Exerts a Whole-Brain Protective Property by Promoting M1? Microglia Quiescence After Experimental Subarachnoid Hemorrhage in Mice.
IL-23-induced macrophage polarization and its pathological roles in mice with imiquimod-induced psoriasis.
Autophagy participates in innate immune defense in lamprey.
Establishing a dual knock-out cell line by lentivirus based combined CRISPR/Cas9 and Loxp/Cre system.
Buffalo oocyte-secreted factors promote cumulus cells apoptosis and the rate of cGMP production but not steroidogenesis.
Prolyl hydroxylases positively regulated LPS-induced inflammation in human gingival fibroblasts via TLR4/MyD88-mediated AKT/NF-κB and MAPK pathways.
Overexpression of CXCL2 inhibits cell proliferation and promotes apoptosis in hepatocellular carcinoma.
PI3K/Akt signaling pathway and Hsp70 activate in hippocampus of rats with chronic manganese sulfate exposure.
Klotho gene-modified BMSCs showed elevated antifibrotic effects by inhibiting the Wnt/β-catenin pathway in kidneys after acute injury.
miR‑29a suppresses the growth and metastasis of hepatocellular carcinoma through IFITM3.
The Scorpion Venom Peptide Smp76 Inhibits Viral Infection by Regulating Type-I Interferon Response.
Elevating ATP-binding cassette transporter G1 improves re-endothelialization function of endothelial progenitor cells via Lyn/Akt/eNOS in diabetic mice.
Phenethyl isothiocyanate inhibits colorectal cancer stem cells by suppressing Wnt/β-catenin pathway.
MicroRNA-146b-3p Promotes Cell Metastasis by Directly Targeting NF2 in Human Papillary Thyroid Cancer.
Expression Analysis of ACSL5 and Wnt2B in Human Congenital Pulmonary Airway Malformations.
Effects of mdig on proliferation and apoptosis of lung cancer cells.
Influencing mechanism of magnolol on expression of BDNF and Bax in rats with cerebral ischemic stroke.
Regulation of hippocampal long term depression by Neuroligin 1.
Cathelicidin-WA attenuates LPS-induced inflammation and redox imbalance through activation of AMPK signaling.
Mechanism and prognostic value of indoleamine 2,3-dioxygenase 1 expressed in hepatocellular carcinoma.
Transcription factor 7-like 2 controls matrix degradation through nuclear factor κB signaling and is repressed by microRNA-155 in nucleus pulposus cells.
PNMA1, regulated by miR-33a-5p, promotes proliferation and EMT in hepatocellular carcinoma by activating the Wnt/β-catenin pathway.
Dynasore-induced potent ubiquitylation of the exon 19 deletion mutant of epidermal growth factor receptor suppresses cell growth and migration in non-small cell lung cancer.
A novel pathway of LPS uptake through syndecan-1 leading to pyroptotic cell death.
A Simplified System to Express Circularized Inhibitors of miRNA for Stable and Potent Suppression of miRNA Functions.
NR2C2-uORF targeting UCA1-miR-627-5p-NR2C2 feedback loop to regulate the malignant behaviors of glioma cells.
MAN1B1 is associated with poor prognosis and modulates proliferation and apoptosis in bladder cancer.
LINC00052/miR-101-3p axis inhibits cell proliferation and metastasis by targeting SOX9 in hepatocellular carcinoma.
Systematic analysis of synergistic proteome modulations in a drug combination of cisplatin and MLN4924.
4'-hydroxywogonin inhibits colorectal cancer angiogenesis by disrupting PI3K/AKT signaling.
Anti-tumoral potential of MDA19 in human osteosarcoma via suppressing PI3K/Akt/mTOR signaling pathway.
Jian-Pi-Yi-Shen Formula ameliorates chronic kidney disease: involvement of mitochondrial quality control network.
Gli2 modulates cell cycle re-entry through autophagy-mediated regulation of the length of primary cilia.
CVB3 Nonstructural 2A Protein Modulates SREBP1a Signaling via the MEK/ERK Pathway.
Perigestational exposure to low doses of PBDE-47 induces excessive ER stress, defective autophagy and the resultant apoptosis contributing to maternal thyroid toxicity.
Dexmedetomidine alleviates cerebral ischemia-reperfusion injury by inhibiting endoplasmic reticulum stress dependent apoptosis through the PERK-CHOP-Caspase-11 pathway.
Metformin regulates atrial SK2 and SK3 expression through inhibiting the PKC/ERK signaling pathway in type 2 diabetic rats.
Epigenetic suppression of E-cadherin expression by Snail2 during the metastasis of colorectal cancer.
Co-targeting PLK1 and mTOR induces synergistic inhibitory effects against esophageal squamous cell carcinoma.
miR-128-3p regulates 3T3-L1 adipogenesis and lipolysis by targeting Pparg and Sertad2.
Radiosensitizing effects of miR-18a-5p on lung cancer stem-like cells via downregulating both ATM and HIF-1α.
NRG1 regulates redox homeostasis via NRF2 in papillary thyroid cancer.
Overexpression of PRDM13 inhibits glioma cells via Rho and GTP enzyme activation protein.
Overexpression of FOXQ1 enhances anti-senescence and migration effects of human umbilical cord mesenchymal stem cells in vitro and in vivo.
Scribble influences cyst formation in autosomal-dominant polycystic kidney disease by regulating Hippo signaling pathway.
Increased Expression of NDRG3 in Mouse Uterus During Embryo Implantation and in Mouse Endometrial Stromal Cells During In Vitro Decidualization.
LncRNA BDNF-AS inhibits proliferation, migration, invasion and EMT in oesophageal cancer cells by targeting miR-214.
Revealing A-Raf functions through its interactome.
miR-205-5p inhibits cell migration and invasion in prostatic carcinoma by targeting ZEB1.
Peri-ovarian adipose tissue contributes to intraovarian control during folliculogenesis in mice.
MicroRNA-135a inhibits cardiac fibrosis induced by isoproterenol via TRPM7 channel.
ITGBL1 promotes migration, invasion and predicts a poor prognosis in colorectal cancer.
Warfarin and vitamin K epoxide reductase: a molecular accounting for observed inhibition.
Anillin is required for tumor growth and regulated by miR-15a/miR-16-1 in HBV-related hepatocellular carcinoma.
HMGB1 knockdown increases MM cell vulnerability by regulating autophagy and DNA damage repair.
Ubiquitin-conjugating enzyme UBE2J1 negatively modulates interferon pathway and promotes RNA virus infection.
MALAT1-miR663a negative feedback loop in colon cancer cell functions through direct miRNA-lncRNA binding.
Hepatocyte Wnts Are Dispensable During Diethylnitrosamine and Carbon Tetrachloride-Induced Injury and Hepatocellular Cancer.
Cold atmospheric plasma conveys selectivity on triple negative breast cancer cells both in vitro and in vivo.
Increased Expression of CD81 in Breast Cancer Tissue is Associated with Reduced Patient Prognosis and Increased Cell Migration and Proliferation in MDA-MB-231 and MDA-MB-435S Human Breast Cancer Cell Lines In Vitro.
Motoneuron Wnts regulate neuromuscular junction development.
Inhibition of mTORC1 signaling protects kidney from irradiation-induced toxicity via accelerating recovery of renal stem-like cells.
Transactive Response DNA-Binding Protein 43 Abnormalities after Traumatic Brain Injury.
Antifertility effectiveness of a novel copper-containing intrauterine device material and its influence on the endometrial environment in rats.
Lanthanum chloride reduces lactate production in primary culture rat cortical astrocytes and suppresses primary co-culture rat cortical astrocyte-neuron lactate transport.
Interleukin-17A participates in podocyte injury by inducing IL-1β secretion through ROS-NLRP3 inflammasome-caspase-1 pathway.
PARP inhibitor olaparib sensitizes cholangiocarcinoma cells to radiation.
Gemin5 plays a role in unassembled-U1 snRNA disposal in SMN-deficient cells.
MDM2 Degrades Deacetylated Nucleolin Through Ubiquitination to Promote Glioma Stem-Like Cell Enrichment for Chemotherapeutic Resistance.
Rolipram Attenuates Early Brain Injury Following Experimental Subarachnoid Hemorrhage in Rats: Possibly via Regulating the SIRT1/NF-κB Pathway.
miR‑21‑5p confers doxorubicin resistance in gastric cancer cells by targeting PTEN and TIMP3.
MiR-151a is involved in the pathogenesis of atopic dermatitis by regulating interleukin-12 receptor β2.
Targeting P-glycoprotein and SORCIN: Dihydromyricetin strengthens anti-proliferative efficiency of adriamycin via MAPK/ERK and Ca2+ -mediated apoptosis pathways in MCF-7/ADR and K562/ADR.
TXNDC5 contributes to rheumatoid arthritis by down-regulating IGFBP1 expression.
Phenformin inhibits cell proliferation and induces cell apoptosis and autophagy in cholangiocarcinoma.
Zoledronic acid sensitizes breast cancer cells to fulvestrant via ERK/HIF-1 pathway inhibition in vivo.
Effect of TLR4/MyD88 signaling pathway on sepsis-associated acute respiratory distress syndrome in rats, via regulation of macrophage activation and inflammatory response.
Screening the expression characteristics of several miRNAs in G93A-SOD1 transgenic mouse: altered expression of miRNA-124 is associated with astrocyte differentiation by targeting Sox2 and Sox9.
TSR2 Induces laryngeal cancer cell apoptosis through inhibiting NF-κB signaling pathway.
Icariside II attenuates myocardial fibrosis by inhibiting nuclear factor-κB and the TGF-β1/Smad2 signalling pathway in spontaneously hypertensive rats.
Apocynum venetum leaf extract reverses depressive-like behaviors in chronically stressed rats by inhibiting oxidative stress and apoptosis.
Ezrin/NF-κB Pathway Regulates EGF-induced Epithelial-Mesenchymal Transition (EMT), Metastasis, and Progression of Osteosarcoma.
Protective effect of methylallyl sulfone in the development of cigarette smoke extract-induced apoptosis in rats and HFL-1 cells.
R-spondin3-LGR4 signaling protects hepatocytes against DMOG-induced hypoxia/reoxygenation injury through activating β-catenin.
Down-regulation of miR-10a-5p promotes proliferation and restricts apoptosis via targeting T-box transcription factor 5 in inflamed synoviocytes.
Characterization of RUNX1T1, an Adipogenesis Regulator in Ovine Preadipocyte Differentiation.
Ehrlichia chaffeensis TRP75 Interacts with Host Cell Targets Involved in Homeostasis, Cytoskeleton Organization, and Apoptosis Regulation To Promote Infection.
The LINC01138 drives malignancies via activating arginine methyltransferase 5 in hepatocellular carcinoma.
RUVBL1, a novel C-RAF-binding protein, activates the RAF/MEK/ERK pathway to promote lung cancer tumorigenesis.
RGC32 Promotes Bleomycin-Induced Systemic Sclerosis in a Murine Disease Model by Modulating Classically Activated Macrophage Function.
Vitamin A pretreatment protects NO-induced bovine mammary epithelial cells from oxidative stress by modulating Nrf2 and NF-κB signaling pathways.
gga-miR-451 Negatively Regulates Mycoplasma gallisepticum (HS Strain)-Induced Inflammatory Cytokine Production via Targeting YWHAZ.
Lysophosphatidic Acid Induces ECM Production via Activation of the Mechanosensitive YAP/TAZ Transcriptional Pathway in Trabecular Meshwork Cells.
Caspase Inhibition Reduces Hepatic Tissue Factor-Driven Coagulation In Vitro and In Vivo.
IncRNA H19 promotes tongue squamous cell carcinoma progression through β-catenin/GSK3β/EMT signaling via association with EZH2.
RIZ1 negatively regulates ubiquitin-conjugating enzyme E2C/UbcH10 via targeting c-Myc in meningioma.
Down-regulation of miR-125a-5p is associated with salivary adenoid cystic carcinoma progression via targeting p38/JNK/ERK signal pathway.
Upregulation of TSPAN12 is associated with the colorectal cancer growth and metastasis.
DDX3 binding with CK1ε was closely related to motor neuron degeneration of ALS by affecting neurite outgrowth.
Levodopa/Benserazide Loaded Microspheres Alleviate L-dopa Induced Dyskinesia through Preventing the Over-Expression of D1R/Shp-2/ERK1/2 Signaling Pathway in a Rat Model of Parkinson's Disease.
The role of the chemokine receptor XCR1 in breast cancer cells.
The Frequency-Dependent Aerobic Exercise Effects of Hypothalamic GABAergic Expression and Cardiovascular Functions in Aged Rats.
Methylation of ZNF331 is an independent prognostic marker of colorectal cancer and promotes colorectal cancer growth.
Downregulation of Mitochondrial Single Stranded DNA Binding Protein (SSBP1) Induces Mitochondrial Dysfunction and Increases the Radiosensitivity in Non-Small Cell Lung Cancer Cells.
HES1 Promotes Colorectal Cancer Cell Resistance To 5-Fu by Inducing Of EMT and ABC Transporter Proteins.
CDC27 Induces Metastasis and Invasion in Colorectal Cancer via the Promotion of Epithelial-To-Mesenchymal Transition.
Interferon-α Promotes the Expression of Cancer Stem Cell Markers in Oral Squamous Cell Carcinoma.
In vitro Cytotoxic Activities of the Oral Platinum(IV) Prodrug Oxoplatin and HSP90 Inhibitor Ganetespib against a Panel of Gastric Cancer Cell Lines.
Carnosic Acid Alleviates BDL-Induced Liver Fibrosis through miR-29b-3p-Mediated Inhibition of the High-Mobility Group Box 1/Toll-Like Receptor 4 Signaling Pathway in Rats.
Antidiabetic Effect of Tibetan Medicine Tang-Kang-Fu-San in db/db Mice via Activation of PI3K/Akt and AMPK Pathways.
Fentanyl Promotes Breast Cancer Cell Stemness and Epithelial-Mesenchymal Transition by Upregulating α1, 6-Fucosylation via Wnt/β-Catenin Signaling Pathway.
Lactobacillus rhamnosus GG Affects Microbiota and Suppresses Autophagy in the Intestines of Pigs Challenged with Salmonella Infantis.
Screening and Identification of the Host Proteins Interacting with Toxoplasma gondii Rhoptry Protein ROP16.
Lab-Attenuated Rabies Virus Causes Abortive Infection and Induces Cytokine Expression in Astrocytes by Activating Mitochondrial Antiviral-Signaling Protein Signaling Pathway.
Protective Effects of Dioscin against Lipopolysaccharide-Induced Acute Lung Injury through Inhibition of Oxidative Stress and Inflammation.
LncRNA ZFAS1 promotes growth and metastasis by regulating BMI1 and ZEB2 in osteosarcoma.
Obatoclax and LY3009120 Efficiently Overcome Vemurafenib Resistance in Differentiated Thyroid Cancer.
miR-381-3p suppresses the proliferation of oral squamous cell carcinoma cells by directly targeting FGFR2.
NRSN2 promotes osteosarcoma cell proliferation and growth through PI3K/Akt/MTOR and Wnt/β-catenin signaling.
Angiopoietin-like protein 2 facilitates non-small cell lung cancer progression by promoting the polarization of M2 tumor-associated macrophages.
Targeting NF-κB/AP-2β signaling to enhance antitumor activity of cisplatin by melatonin in hepatocellular carcinoma cells.
Exogenous H2S restores ischemic post-conditioning-induced cardioprotection through inhibiting endoplasmic reticulum stress in the aged cardiomyocytes.
Oral Administration of Lactobacillus rhamnosus GG Ameliorates Salmonella Infantis-Induced Inflammation in a Pig Model via Activation of the IL-22BP/IL-22/STAT3 Pathway.
In-Cell Western Assays to Evaluate Hantaan Virus Replication as a Novel Approach to Screen Antiviral Molecules and Detect Neutralizing Antibody Titers.
Selenomethionine Attenuates the Amyloid-β Level by Both Inhibiting Amyloid-β Production and Modulating Autophagy in Neuron-2a/AβPPswe Cells.
MiR-142-5p Suppresses Tumorigenesis by Targeting PIK3CA in Non-Small Cell Lung Cancer.
Iridoids with Genipin Stem Nucleus Inhibit Lipopolysaccharide-Induced Inflammation and Oxidative Stress by Blocking the NF-κB Pathway in Polycystic Ovary Syndrome.
The USP7 Inhibitor P5091 Induces Cell Death in Ovarian Cancers with Different P53 Status.
Involvement of S100A8/A9-TLR4-NLRP3 Inflammasome Pathway in Contrast-Induced Acute Kidney Injury.
The Lncrna-TUG1/EZH2 Axis Promotes Pancreatic Cancer Cell Proliferation, Migration and EMT Phenotype Formation Through Sponging Mir-382.
Deoxyelephantopin Induces Reactive Oxygen Species-Mediated Apoptosis and Autophagy in Human Osteosarcoma Cells.
CDC5L Promotes hTERT Expression and Colorectal Tumor Growth.
SOX6 Downregulation Induces γ-Globin in Human β-Thalassemia Major Erythroid Cells.
Neutrophil Extracellular Traps Are Pathogenic in Ventilator-Induced Lung Injury and Partially Dependent on TLR4.
Resveratrol Prevents ROS-Induced Apoptosis in High Glucose-Treated Retinal Capillary Endothelial Cells via the Activation of AMPK/Sirt1/PGC-1α Pathway.
Differentiation of Human Amniotic Mesenchymal Stem Cells into Human Anterior Cruciate Ligament Fibroblast Cells by In Vitro Coculture.
Antidiabetic Effect of Tibetan Medicine Tang-Kang-Fu-San on High-Fat Diet and Streptozotocin-Induced Type 2 Diabetic Rats.
Salusin-β Is Involved in Diabetes Mellitus-Induced Endothelial Dysfunction via Degradation of Peroxisome Proliferator-Activated Receptor Gamma.
Electroacupuncture Alleviates Postoperative Cognitive Dysfunction in Aged Rats by Inhibiting Hippocampal Neuroinflammation Activated via Microglia/TLRs Pathway.
HIV-1 Transactivator Protein Induces ZO-1 and Neprilysin Dysfunction in Brain Endothelial Cells via the Ras Signaling Pathway.
Long-Term Effects of TCM Yangqing Kangxian Formula on Bleomycin-Induced Pulmonary Fibrosis in Rats via Regulating Nuclear Factor-κB Signaling.
Synthetic Isoliquiritigenin Inhibits Human Tongue Squamous Carcinoma Cells through Its Antioxidant Mechanism.
ROR2 receptor promotes the migration of osteosarcoma cells in response to Wnt5a.
HSPB8 Promotes the Fusion of Autophagosome and Lysosome during Autophagy in Diabetic Neurons.
LncRNA AFAP1-AS Functions as a Competing Endogenous RNA to Regulate RAP1B Expression by sponging miR-181a in the HSCR.
Exosomes Derived from Human Pulmonary Artery Endothelial Cells Shift the Balance between Proliferation and Apoptosis of Smooth Muscle Cells.
Resveratrol ameliorates diet-induced dysregulation of lipid metabolism in zebrafish (Danio rerio).
Caveolin1 protects against diet induced hepatic lipid accumulation in mice.
Imatinib attenuates cardiac fibrosis by inhibiting platelet-derived growth factor receptors activation in isoproterenol induced model.
A mutation in the CACNA1C gene leads to early repolarization syndrome with incomplete penetrance: A Chinese family study.
Role of keratin 24 in human epidermal keratinocytes.
Far-infrared suppresses skin photoaging in ultraviolet B-exposed fibroblasts and hairless mice.
Increased expression of protein kinase CK2α correlates with poor patient prognosis in epithelial ovarian cancer.
Aerobic exercise regulates Rho/cofilin pathways to rescue synaptic loss in aged rats.
Rottlerin as a therapeutic approach in psoriasis: Evidence from in vitro and in vivo studies.
Down-regulation of the klf5-c-Myc interaction due to klf5 phosphorylation mediates resveratrol repressing the caveolin-1 transcription through the PI3K/PKD1/Akt pathway.
XRCC5 cooperates with p300 to promote cyclooxygenase-2 expression and tumor growth in colon cancers.
MITA/STING and Its Alternative Splicing Isoform MRP Restrict Hepatitis B Virus Replication.
Gold nanoparticles attenuate metastasis by tumor vasculature normalization and epithelial-mesenchymal transition inhibition.
Knockdown of Long Non-Coding RNA KCNQ1OT1 Restrained Glioma Cells' Malignancy by Activating miR-370/CCNE2 Axis.
Involvement of endoplasmic reticulum stress in formalin-induced pain is attenuated by 4-phenylbutyric acid.
UNBS5162 inhibits proliferation of human retinoblastoma cells by promoting cell apoptosis.
The Effect of MCM3AP-AS1/miR-211/KLF5/AGGF1 Axis Regulating Glioblastoma Angiogenesis.
Circ-104916 is downregulated in gastric cancer and suppresses migration and invasion of gastric cancer cells.
PIK3CA expression in diffuse large B cell lymphoma tissue and the effect of its knockdown in vitro.
The Role of HOTAIR/miR-148b-3p/USF1 on Regulating the Permeability of BTB.
Downregulation of the Repressor Element 1-Silencing Transcription Factor (REST) Is Associated with Akt-mTOR and Wnt-β-Catenin Signaling in Prion Diseases Models.
Tail vein injection of mmLDL upregulates mouse mesenteric artery ETB receptors via activation of the ERK1/2 pathway.
Calreticulin regulates TGF-β1-induced epithelial mesenchymal transition through modulating Smad signaling and calcium signaling.
Ehrlichia chaffeensis TRP120 Moonlights as a HECT E3 Ligase Involved in Self- and Host Ubiquitination To Influence Protein Interactions and Stability for Intracellular Survival.
Ligustrazine modulates renal cysteine biosynthesis in rats exposed to cadmium.
The transcription factor cyclic adenosine 3',5'-monophosphate response element-binding protein enhances the odonto/osteogenic differentiation of stem cells from the apical papilla.
lncRNA-PVT1 Facilitates Invasion Through Upregulation of MMP9 in Nonsmall Cell Lung Cancer Cell.
Stool DNA Test of Methylated Syndecan-2 for the Early Detection of Colorectal Neoplasia.
Vertebrate Lonesome Kinase Regulated Extracellular Matrix Protein Phosphorylation, Cell Shape, and Adhesion in Trabecular Meshwork Cells.
An oligodeoxynucleotide with AAAG repeats significantly attenuates burn-induced systemic inflammatory responses via inhibiting interferon regulatory factor 5 pathway.
TNF-α promotes survival and migration of MSCs under oxidative stress via NF-κB pathway to attenuate intimal hyperplasia in vein grafts.
Assessment of tris (1, 3-dichloro-2-propyl) phosphate toxicology in PC12 cells by using digital gene expression profiling.
Attenuation of doxorubicin-induced cardiotoxicity by esculetin through modulation of Bmi-1 expression.
Dioscin, a potent ITGA5 inhibitor, reduces the synthesis of collagen against liver fibrosis: Insights from SILAC-based proteomics analysis.
Predictive single nucleotide polymorphism markers for acute oral mucositis in patients with nasopharyngeal carcinoma treated with radiotherapy.
Hsp90 activator Aha1 drives production of pathological tau aggregates.
Sirt6 deficiency exacerbates podocyte injury and proteinuria through targeting Notch signaling.
FAM83D, a microtubule-associated protein, promotes tumor growth and progression of human gastric cancer.
Numb positively regulates autophagic flux via regulating lysosomal function.
Overexpression of miR-135b-5p promotes unfavorable clinical characteristics and poor prognosis via the repression of SFRP4 in pancreatic cancer.
Regulation of the epithelial Na+ channel by paraoxonase-2.
Long non-coding RNA NEAT1 regulates epithelial membrane protein 2 expression to repress nasopharyngeal carcinoma migration and irradiation-resistance through miR-101-3p as a competing endogenous RNA mechanism.
Heat-killed salmonella typhimurium (HKST) protects mice against radiation in TLR4-dependent manner.
Testosterone regulates 3T3-L1 pre-adipocyte differentiation and epididymal fat accumulation in mice through modulating macrophage polarization.
Cloning, expression pattern, and potential role of apoptosis inhibitor 5 in the termination of embryonic diapause and early embryo development of Artemia sinica.
Ezrin as a possible diagnostic and/or prognostic biomarker in mice lymphatic metastatic hepatocellular carcinoma in vivo.
Phorbol esters dPPA/dPA promote furin expression involving transcription factor CEBPβ in neuronal cells.
Live-cell visualization of gasdermin D-driven pyroptotic cell death.
ORMDL3 Facilitates the Survival of Splenic B Cells via an ATF6α-Endoplasmic Reticulum Stress-Beclin1 Autophagy Regulatory Pathway.
New Insights Into the Role of Estrogens in Male Fertility Based on Findings in Aromatase-Deficient Zebrafish.
Lithium alleviates neurotoxic prion peptide-induced synaptic damage and neuronal death partially by the upregulation of nuclear target REST and the restoration of Wnt signaling.
Role of Pannexin1 channels in the resistance of I-10 testicular cancer cells to cisplatin mediated by ATP/IP3 pathway.
Cadmium chloride-induced testicular toxicity in male wistar rats; prophylactic effect of quercetin, and assessment of testicular recovery following cadmium chloride withdrawal.
In vitro anticancer activities of osthole against renal cell carcinoma cells.
Metformin Inhibits Porphyromonas gingivalis Lipopolysaccharide-Influenced Inflammatory Response in Human Gingival Fibroblasts via Regulating Activating Transcription Factor-3 Expression.
A potential contribution of dipeptidyl peptidase-4 by the mediation of monocyte differentiation in the development and progression of abdominal aortic aneurysms.
CISD2 enhances the chemosensitivity of gastric cancer through the enhancement of 5-FU-induced apoptosis and the inhibition of autophagy by AKT/mTOR pathway.
Propofol inhibits invasion and proliferation of C6 glioma cells by regulating the Ca2+ permeable AMPA receptor-system xc- pathway.
Trichostatin A attenuates oxidative stress-mediated myocardial injury through the FoxO3a signaling pathway.
Zinc finger protein 307 functions as a tumor‑suppressor and inhibits cell proliferation by inducing apoptosis in hepatocellular carcinoma.
Varicella-zoster virus ORF7 interacts with ORF53 and plays a role in its trans-Golgi network localization.
The effects of fluoride on neuronal function occurs via cytoskeleton damage and decreased signal transmission.
Proteasomal degradation of T. gondii ROP18 requires Derlin2.
ERβ compensates for the absence of ERα function to promote osteoblast viability by inhibition of SOST signaling.
Caveolin 1-related autophagy initiated by aldosterone-induced oxidation promotes liver sinusoidal endothelial cells defenestration.
Neuroprotective Effects of Loganin on MPTP-Induced Parkinson's Disease Mice: Neurochemistry, Glial Reaction and Autophagy Studies.
RTN1-C mediates cerebral ischemia/reperfusion injury via ER stress and mitochondria-associated apoptosis pathways.
Circular RNA HIPK2 regulates astrocyte activation via cooperation of autophagy and ER stress by targeting MIR124-2HG.
Calreticulin promotes EGF-induced EMT in pancreatic cancer cells via Integrin/EGFR-ERK/MAPK signaling pathway.
ANP promotes proliferation and inhibits apoptosis of ovarian granulosa cells by NPRA/PGRMC1/EGFR complex and improves ovary functions of PCOS rats.
Protective Effect of Flavonoids from Ziziphus jujuba cv. Jinsixiaozao against Acetaminophen-Induced Liver Injury by Inhibiting Oxidative Stress and Inflammation in Mice.
Centriolin, a centriole-appendage protein, regulates peripheral spindle migration and asymmetric division in mouse meiotic oocytes.
MicroRNA-20a-mediated loss of autophagy contributes to breast tumorigenesis by promoting genomic damage and instability.
Linc-RoR promotes MAPK/ERK signaling and confers estrogen-independent growth of breast cancer.
MicroRNA-21 suppresses ox-LDL-induced human aortic endothelial cells injuries in atherosclerosis through enhancement of autophagic flux: Involvement in promotion of lysosomal function.
Rab11a is required for porcine reproductive and respiratory syndrome virus induced autophagy to promote viral replication.
Aneuploid Cell Survival Relies upon Sphingolipid Homeostasis.
Far infrared promotes wound healing through activation of Notch1 signaling.
Role of NF-κB/GATA3 in the inhibition of lysyl oxidase by IL-1β in human amnion fibroblasts.
Long non-coding RNA HOTTIP promotes hypoxia-induced epithelial-mesenchymal transition of malignant glioma by regulating the miR-101/ZEB1 axis.
Berberine activates caspase-9/cytochrome c-mediated apoptosis to suppress triple-negative breast cancer cells in vitro and in vivo.
Spiroplasma eriocheiris induces mouse 3T6-Swiss albino cell apoptosis that associated with the infection mechanism.
Effects of melatonin on the proliferation and differentiation of human dental pulp cells.
MYC protein dysregulation is driven by BCR-PI3K signalling in diffuse large B-cell lymphoma.
Effectively enhancing cytotoxic and apoptotic effects of alpha-momorcharin by integrating a heparin-binding peptide.
Artesunate induces apoptosis via inhibition of STAT3 in THP-1 cells.
MAPK/p38 regulation of cytoskeleton rearrangement accelerates induction of macrophage activation by TLR4, but not TLR3.
Platelet rich plasma promotes skeletal muscle cell migration in association with up-regulation of FAK, paxillin, and F-Actin formation.
Endothelial cell SHP-2 negatively regulates neutrophil adhesion and promotes transmigration by enhancing ICAM-1-VE-cadherin interaction.
Sodium selenate activated Wnt/β-catenin signaling and repressed amyloid-β formation in a triple transgenic mouse model of Alzheimer's disease.
Neuroprotection of hypoxic postconditioning against global cerebral ischemia through influencing posttranslational regulations of heat shock protein 27 in adult rats.
Rho-kinase inhibitor Y-27632 facilitates the proliferation, migration and pluripotency of human periodontal ligament stem cells.
Focal adhesion kinase family is involved in matrix contraction by transdifferentiated Müller cells.
IFNA2 p.Ala120Thr impairs the inhibitory activity of Interferon-α2 against the hepatitis B virus through altering its binding to the receptor.
Reactive oxygen species-responsive polymeric nanoparticles for alleviating sepsis-induced acute liver injury in mice.
Downregulated long non-coding RNA TCONS_00068220 upregulates apoptosis in gastric cancer cells.
p63 inhibits CD44+/CD24- cell proliferation and chemoresistance in papillary thyroid carcinoma cells.
Generation of apoptosis-resistant HEK293 cells with CRISPR/Cas mediated quadruple gene knockout for improved protein and virus production.
β-d-glucan from Antrodia Camphorata ameliorates LPS-induced inflammation and ROS production in human hepatocytes.
Cell contact and pressure control of YAP localization and clustering revealed by super-resolution imaging.
Insulin-like growth factor 2 mRNA binding protein 3 (IGF2BP3) promotes lung tumorigenesis via attenuating p53 stability.
Targeted Metabolomics Reveals Abnormal Hepatic Energy Metabolism by Depletion of β-Carotene Oxygenase 2 in Mice.
DC2 and KCP2 mediate the interaction between the oligosaccharyltransferase and the ER translocon.
Curcumin inhibits bladder cancer stem cells by suppressing Sonic Hedgehog pathway.
Upregulation of SOX2 activated LncRNA PVT1 expression promotes breast cancer cell growth and invasion.
Cholecalciterol cholesterol emulsion attenuates experimental autoimmune myocarditis in mice via inhibition of the pyroptosis signaling pathway.
Autocrine Interleukin-10 Mediates Glucagon-Like Peptide-1 Receptor-Induced Spinal Microglial β-Endorphin Expression.
Metformin reverses bFGF-induced epithelial-mesenchymal transition in HCC cells.
MiR-16-5p mediates a positive feedback loop in EV71-induced apoptosis and suppresses virus replication.
Proteomics and metabolomics analysis of hepatic mitochondrial metabolism in alcohol-preferring and non-preferring rats.
Pim-3 as a potential predictor of chemoradiotherapy resistance in locally advanced rectal cancer patients.
AKAP95-mediated nuclear anchoring of PKA mediates cortisol-induced PTGS2 expression in human amnion fibroblasts.
Levels of Leydig cell autophagy regulate the fertility of male naked mole-rats.
High expression of PDLIM5 facilitates cell tumorigenesis and migration by maintaining AMPK activation in prostate cancer.
Different miR-21-3p isoforms and their different features in colorectal cancer.
DLX3 promotes bone marrow mesenchymal stem cell proliferation through H19/miR-675 axis.
Quercetin exerts synergetic anti-cancer activity with 10-hydroxy camptothecin.
Bcl-3 is a novel biomarker of renal fibrosis in chronic kidney disease.
FBXW8-dependent degradation of MRFAP1 in anaphase controls mitotic cell death.
Comparative study of macrophages in naked mole rats and ICR mice.
iASPP Is an Antioxidative Factor and Drives Cancer Growth and Drug Resistance by Competing with Nrf2 for Keap1 Binding.
CHST6 mutation screening and endoplasmatic reticulum stress in macular corneal dystrophy.
KSRP specifies monocytic and granulocytic differentiation through regulating miR-129 biogenesis and RUNX1 expression.
A Single-Amino-Acid Substitution at Position 225 in Hemagglutinin Alters the Transmissibility of Eurasian Avian-Like H1N1 Swine Influenza Virus in Guinea Pigs.
Expression and Subcellular Localization of the Kaposi's Sarcoma-Associated Herpesvirus K15P Protein during Latency and Lytic Reactivation in Primary Effusion Lymphoma Cells.
HERP Binds TBK1 To Activate Innate Immunity and Repress Virus Replication in Response to Endoplasmic Reticulum Stress.
Designed inhibitor for nuclear localization signal of polo-like kinase 1 induces mitotic arrest.
The tumor suppressor p53 regulates autophagosomal and lysosomal biogenesis in lung cancer cells by targeting transcription factor EB.
DLX3 mutation negatively regulates odontogenic differentiation of human dental pulp cells.
Cynandione A attenuates neuropathic pain through p38β MAPK-mediated spinal microglial expression of β-endorphin.
Involvement of FMRP in Primary MicroRNA Processing via Enhancing Drosha Translation.
The mechanism of epithelial-mesenchymal transition induced by TGF-β1 in neuroblastoma cells.
E-Prostanoid 3 Receptor Mediates Sprouting Angiogenesis Through Suppression of the Protein Kinase A/β-Catenin/Notch Pathway.
Human recombinant RNASET2-induced inflammatory response and connective tissue remodeling in the medicinal leech.
Fn14 hepatic progenitor cells are associated with liver fibrosis in biliary atresia.
Shen-Yuan-Dan Capsule Inhibiting Inflammatory Reaction by Regulating Insulin Receptor Substrate 1/PI3K/Akt/NF-κB Signaling Pathway in Apoliprotein E Knockout Mice Fed with a High-Fat Diet.
Clinical Significance and Tumor-Suppressive Function of miR-516b in Nonsmall Cell Lung Cancer.
Lethal concentration of perfluoroisobutylene induces acute lung injury in mice mediated via cytokine storm, oxidative stress and apoptosis.
BNIP3 promotes the motility and migration of keratinocyte under hypoxia.
TSA protects H9c2 cells against thapsigargin-induced apoptosis related to endoplasmic reticulum stress-mediated mitochondrial injury.
lncRNA-HIT promotes cell proliferation of non-small cell lung cancer by association with E2F1.
EphrinB-EphB Signaling Induces Hyperalgesia through ERK5/CREB Pathway in Rats.
siRNA-mediated knockdown of ID1 disrupts Nanog- and Oct-4-mediated cancer stem cell-likeness and resistance to chemotherapy in gastric cancer cells.
PCSK9 regulates apoptosis in human lung adenocarcinoma A549 cells via endoplasmic reticulum stress and mitochondrial signaling pathways.
Dihydroartemisin inhibits glioma invasiveness via a ROS to P53 to β-catenin signaling.
Galectin-3 mediates the pulmonary arterial hypertension-induced right ventricular remodeling through interacting with NADPH oxidase 4.
A novel inducible lentiviral system for multi-gene expression with human HSP70 promoter and tetracycline-induced promoter.
Upregulation of the lncRNA Meg3 induces autophagy to inhibit tumorigenesis and progression of epithelial ovarian carcinoma by regulating activity of ATG3.
Atgl gene deletion predisposes to proximal tubule damage by impairing the fatty acid metabolism.
miR-29a regulated ER-positive breast cancer cell growth and invasion and is involved in the insulin signaling pathway.
Fatty acid synthesis is critical for stem cell pluripotency via promoting mitochondrial fission.
MiR-23a-5p modulates mycobacterial survival and autophagy during mycobacterium tuberculosis infection through TLR2/MyD88/NF-κB pathway by targeting TLR2.
Identification and activation of TLR4-mediated signalling pathways by alginate-derived guluronate oligosaccharide in RAW264.7 macrophages.
CRISPR/Cas9 Screens Reveal Epstein-Barr Virus-Transformed B Cell Host Dependency Factors.
Chromium contributes to human bronchial epithelial cell carcinogenesis by activating Gli2 and inhibiting autophagy.
7-O-Geranylquercetin induces apoptosis in gastric cancer cells via ROS-MAPK mediated mitochondrial signaling pathway activation.
Vascular endothelial cells senescence is associated with NOD-like receptor family pyrin domain-containing 3 (NLRP3) inflammasome activation via reactive oxygen species (ROS)/thioredoxin-interacting protein (TXNIP) pathway.
Melatonin synergizes the chemotherapeutic effect of 5-fluorouracil in colon cancer by suppressing PI3K/AKT and NF-κB/iNOS signaling pathways.
Hepatic deletion of X-box binding protein 1 impairs bile acid metabolism in mice.
PBDE-209 exposure damages learning and memory ability in rats potentially through increased autophagy and apoptosis in the hippocampus neuron.
miR-194 functions as a novel modulator of cellular senescence in mouse embryonic fibroblasts.
High mobility group box 1/toll-like receptor 4/myeloid differentiation factor 88 signaling promotes progression of gastric cancer.
MicroRNA-133b is regulated by TAp63 while no gene mutation is present in colorectal cancer.
Knockdown of NUPR1 inhibits the proliferation of glioblastoma cells via ERK1/2, p38 MAPK and caspase-3.
Conditional knockout of Fgf13 in murine hearts increases arrhythmia susceptibility and reveals novel ion channel modulatory roles.
Epidermal CD147 expression plays a key role in IL-22-induced psoriatic dermatitis.
A 3 base pair deletion in TBX1 leads to reduced protein expression and transcriptional activity.
Neuroprotective effects of lycopene in spinal cord injury in rats via antioxidative and anti-apoptotic pathway.
Dectin-2 Deficiency Modulates Th1 Differentiation and Improves Wound Healing After Myocardial Infarction.
Transducin (β)-like 1 X-linked receptor 1 promotes gastric cancer progression via the ERK1/2 pathway.
IL-6 secreted by cancer-associated fibroblasts promotes epithelial-mesenchymal transition and metastasis of gastric cancer via JAK2/STAT3 signaling pathway.
Nuclear localization of Beclin 1 promotes radiation-induced DNA damage repair independent of autophagy.
Anti-tumor effect of evodiamine by inducing Akt-mediated apoptosis in hepatocellular carcinoma.
PPARβ/δ, a Novel Regulator for Vascular Smooth Muscle Cells Phenotypic Modulation and Vascular Remodeling after Subarachnoid Hemorrhage in Rats.
Molecular signaling underlying bulleyaconitine A (BAA)-induced microglial expression of prodynorphin.
Whole-exome sequencing identified a homozygous BRDT mutation in a patient with acephalic spermatozoa.
The promotion of the transformation of quiescent gastric cancer stem cells by IL-17 and the underlying mechanisms.
Combined transplantation of human mesenchymal stem cells and human retinal progenitor cells into the subretinal space of RCS rats.
Cytoskeleton-associated protein 5 and clathrin heavy chain binding regulates spindle assembly in mouse oocytes.
Nonstructural Protein 4 of Porcine Reproductive and Respiratory Syndrome Virus Modulates Cell Surface Swine Leukocyte Antigen Class I Expression by Downregulating β2-Microglobulin Transcription.
Selenomethionine Mitigates Cognitive Decline by Targeting Both Tau Hyperphosphorylation and Autophagic Clearance in an Alzheimer's Disease Mouse Model.
The MLKL Channel in Necroptosis Is an Octamer Formed by Tetramers in a Dyadic Process.
miR-137 downregulates c-kit expression in acute myeloid leukemia.
miR-19 targeting of GSK3β mediates sulforaphane suppression of lung cancer stem cells.
Cr(VI) induces cytotoxicity in vitro through activation of ROS-mediated endoplasmic reticulum stress and mitochondrial dysfunction via the PI3K/Akt signaling pathway.
Simvastatin Inhibits IL-1β-Induced Apoptosis and Extracellular Matrix Degradation by Suppressing the NF-kB and MAPK Pathways in Nucleus Pulposus Cells.
Apobec-1 complementation factor regulates cell migration and apoptosis through Dickkopf1 by acting on its 3' untranslated region in MCF7 cells.
RON and c-Met facilitate metastasis through the ERK signaling pathway in prostate cancer cells.
Cooperation of Musashi-2, Numb, MDM2, and P53 in drug resistance and malignant biology of pancreatic cancer.
Role of the Wnt/β-catenin signaling pathway in inducing apoptosis and renal fibrosis in 5/6-nephrectomized rats.
Overexpressed miR-9 promotes tumor metastasis via targeting E-cadherin in serous ovarian cancer.
Nucleotide-binding oligomerization domain (NOD) signaling defects and cell death susceptibility cannot be uncoupled in X-linked inhibitor of apoptosis (XIAP)-driven inflammatory disease.
Loss of the novel mitochondrial protein FAM210B promotes metastasis via PDK4-dependent metabolic reprogramming.
Upconversion nanoparticle-mediated photodynamic therapy induces autophagy and cholesterol efflux of macrophage-derived foam cells via ROS generation.
Erythropoietin activates SIRT1 to protect human cardiomyocytes against doxorubicin-induced mitochondrial dysfunction and toxicity.
(-)-Epigallocatechin-3-Gallate Inhibits Colorectal Cancer Stem Cells by Suppressing Wnt/β-Catenin Pathway.
miR-181d/MALT1 regulatory axis attenuates mesenchymal phenotype through NF-κB pathways in glioblastoma.
AQP9-induced cell cycle arrest is associated with RAS activation and improves chemotherapy treatment efficacy in colorectal cancer.
Total Flavonoids of Drynariae Rhizoma Prevent Bone Loss Induced by Hindlimb Unloading in Rats.
Chemokine receptor CXCR4 regulates CaMKII/CREB pathway in spinal neurons that underlies cancer-induced bone pain.
Long-Term Dietary Supplementation with Selenium-Enriched Yeast Improves Cognitive Impairment, Reverses Synaptic Deficits, and Mitigates Tau Pathology in a Triple Transgenic Mouse Model of Alzheimer's Disease.
Expression of estrogen receptors and androgen receptor and their clinical significance in gastric cancer.
Clonorchis sinensis lysophospholipase A upregulates IL-25 expression in macrophages as a potential pathway to liver fibrosis.
RUFY3 interaction with FOXK1 promotes invasion and metastasis in colorectal cancer.
CDK4 protein is degraded by anaphase-promoting complex/cyclosome in mitosis and reaccumulates in early G1 phase to initiate a new cell cycle in HeLa cells.
Quantitative Proteomic Analysis of Mosquito C6/36 Cells Reveals Host Proteins Involved in Zika Virus Infection.
BST2 confers cisplatin resistance via NF-κB signaling in nasopharyngeal cancer.
The phosphatase Pgam5 antagonizes Wnt/β-Catenin signaling in embryonic anterior-posterior axis patterning.
Promoting tumorigenesis in nasopharyngeal carcinoma, NEDD8 serves as a potential theranostic target.
cMyBP-C was decreased via KLHL3-mediated proteasomal degradation in congenital heart diseases.
Wogonin mitigates nonalcoholic fatty liver disease via enhancing PPARα/AdipoR2, in vivo and in vitro.
Garlic-derived organosulfur compound exerts antitumor efficacy via activation of MAPK pathway and modulation of cytokines in SGC-7901 tumor-bearing mice.
Timing of autophagy and apoptosis during posterior silk gland degeneration in Bombyx mori.
RUVBL1-ITFG1 interaction is required for collective invasion in breast cancer.
Correlation study of DNA methylation of WNT6 gene with osteosarcoma in children.
Bacterial effector NleL promotes enterohemorrhagic E. coli-induced attaching and effacing lesions by ubiquitylating and inactivating JNK.
USP19 suppresses cellular type I interferon signaling by targeting TRAF3 for deubiquitination.
Cigarette smoke extract induces EGFR-TKI resistance via promoting EGFR signaling pathway and ROS generation in NSCLC cell lines.
5T4-specific chimeric antigen receptor modification promotes the immune efficacy of cytokine-induced killer cells against nasopharyngeal carcinoma stem cell-like cells.
SNORD47, a box C/D snoRNA, suppresses tumorigenesis in glioblastoma.
Down-regulation of UBC9 increases the sensitivity of hepatocellular carcinoma to doxorubicin.
Fork Head Box Class O1 (FOXO1) Activates Bim Expression to Mediate Cardiac Apoptosis in Chronic Intermittent Hypoxia-Induced Cardiac Hypertrophy.
Correction: Phosphoglycerate mutase 1 regulates dNTP pool and promotes homologous recombination repair in cancer cells.
Autophagosome maturation mediated by Rab7 contributes to neuroprotection of hypoxic preconditioning against global cerebral ischemia in rats.
FOXQ1 regulates senescence-associated inflammation via activation of SIRT1 expression.
KMT2A promotes melanoma cell growth by targeting hTERT signaling pathway.
A hydrophobic residue in the TALE homeodomain of PBX1 promotes epithelial-to-mesenchymal transition of gastric carcinoma.
Novel function of pregnancy-associated plasma protein A: promotes endometrium receptivity by up-regulating N-fucosylation.
Hydrogen sulfide attenuates cardiac injury in takotsubo cardiomyopathy by alleviating oxidative stress.
Feeding influences adipose tissue responses to exercise in overweight men.
Resveratrol Pretreatment Decreases Ischemic Injury and Improves Neurological Function Via Sonic Hedgehog Signaling After Stroke in Rats.
H/ACA Box Small Nucleolar RNA 7A Promotes the Self-Renewal of Human Umbilical Cord Mesenchymal Stem Cells.
Runx2, a novel regulator for goblet cell differentiation and asthma development.
Cigarette smoke extract-induced proliferation of normal human urothelial cells via the MAPK/AP-1 pathway.
Anti-inflammatory and neuroprotective effects of sanguinarine following cerebral ischemia in rats.
Forkhead box P3 regulates ARHGAP15 expression and affects migration of glioma cells through the Rac1 signaling pathway.
Long-term exposure to a 'safe' dose of bisphenol A reduced protein acetylation in adult rat testes.
Identification of a novel missense mutation of MIP in a Chinese family with congenital cataracts by target region capture sequencing.
The RhoA/ROCK Pathway Ameliorates Adhesion and Inflammatory Infiltration Induced by AGEs in Glomerular Endothelial Cells.
Endothelial microparticles are increased in congenital heart diseases and contribute to endothelial dysfunction.
Genetic and epigenetic silencing of mircoRNA-506-3p enhances COTL1 oncogene expression to foster non-small lung cancer progression.
Metformin Induces Growth Inhibition and Cell Cycle Arrest by Upregulating MicroRNA34a in Renal Cancer Cells.
DAZ-interacting Protein 1 (Dzip1) Phosphorylation by Polo-like Kinase 1 (Plk1) Regulates the Centriolar Satellite Localization of the BBSome Protein during the Cell Cycle.
Resveratrol reverses Doxorubicin resistance by inhibiting epithelial-mesenchymal transition (EMT) through modulating PTEN/Akt signaling pathway in gastric cancer.
Hormetic effect of panaxatriol saponins confers neuroprotection in PC12 cells and zebrafish through PI3K/AKT/mTOR and AMPK/SIRT1/FOXO3 pathways.
Up-regulation of syncytin-1 contributes to TNF-α-enhanced fusion between OSCC and HUVECs partly via Wnt/β-catenin-dependent pathway.
B7-H3 regulates lipid metabolism of lung cancer through SREBP1-mediated expression of FASN.
Highly expressed lncRNA CCND2-AS1 promotes glioma cell proliferation through Wnt/β-catenin signaling.
Secreted miR-27a Induced by Cyclic Stretch Modulates the Proliferation of Endothelial Cells in Hypertension via GRK6.
Identification of TDP-43 as an oncogene in melanoma and its function during melanoma pathogenesis.
A comprehensive platform for the analysis of ubiquitin-like protein modifications using in vivo biotinylation.
Melatonin ameliorates amygdala-dependent emotional memory deficits in Tg2576 mice by up-regulating the CREB/c-Fos pathway.
Retromer- and WASH-dependent sorting of nutrient transporters requires a multivalent interaction network with ANKRD50.
Contractile forces at tricellular contacts modulate epithelial organization and monolayer integrity.
CRB3 regulates contact inhibition by activating the Hippo pathway in mammary epithelial cells.
TRIM52: A nuclear TRIM protein that positively regulates the nuclear factor-kappa B signaling pathway.
MicroRNA-22 regulates inflammation and angiogenesis via targeting VE-cadherin.
Upregulation of miR-146a by YY1 depletion correlates with delayed progression of prostate cancer.
MicroRNA-503-5p inhibits stretch-induced osteogenic differentiation and bone formation.
Expression of glia maturation factor γ is associated with colorectal cancer metastasis and its downregulation suppresses colorectal cancer cell migration and invasion in vitro.
Long Noncoding RNA DANCR Is a Positive Regulator of Proliferation and Chondrogenic Differentiation in Human Synovium-Derived Stem Cells.
Diethylstilbestrol activates CatSper and disturbs progesterone actions in human spermatozoa.
Kukoamine A Prevents Radiation-Induced Neuroinflammation and Preserves Hippocampal Neurogenesis in Rats by Inhibiting Activation of NF-κB and AP-1.
Phosphoglycerate mutase 1 regulates dNTP pool and promotes homologous recombination repair in cancer cells.
The effect of nuclear factor erythroid 2-related factor/antioxidant response element signalling pathway in the lanthanum chloride-induced impairment of learning and memory in rats.
GAPDH-mediated posttranscriptional regulations of sodium channel Scn1a and Scn3a genes under seizure and ketogenic diet conditions.
Triggering of apoptosis in osteosarcoma cells by graphene/single-walled carbon nanotube hybrids via the ROS-mediated mitochondrial pathway.
Quercetin induces autophagy via FOXO1-dependent pathways and autophagy suppression enhances quercetin-induced apoptosis in PASMCs in hypoxia.
Up-Regulation of RFC3 Promotes Triple Negative Breast Cancer Metastasis and is Associated With Poor Prognosis Via EMT.
LncRNA AK023948 is a positive regulator of AKT.
Decreased expression of STING predicts poor prognosis in patients with gastric cancer.
A novel peptide, 9R-P201, strongly inhibits the viability, proliferation and migration of liver cancer HepG2 cells and induces apoptosis by down-regulation of FoxM1 expression.
Luteolin suppresses gastric cancer progression by reversing epithelial-mesenchymal transition via suppression of the Notch signaling pathway.
HnRNP-L mediates bladder cancer progression by inhibiting apoptotic signaling and enhancing MAPK signaling pathways.
Simvastatin suppresses the DNA replication licensing factor MCM7 and inhibits the growth of tamoxifen-resistant breast cancer cells.
Method for Dual Viral Vector Mediated CRISPR-Cas9 Gene Disruption in Primary Human Endothelial Cells.
RELM-β promotes human pulmonary artery smooth muscle cell proliferation via FAK-stimulated surviving.
Sinomenine hydrochloride attenuates the proliferation, migration, invasiveness, angiogenesis and epithelial-mesenchymal transition of clear-cell renal cell carcinoma cells via targeting Smad in vitro.
Long non-coding RNA CASC15 is upregulated in hepatocellular carcinoma and facilitates hepatocarcinogenesis.
MTA-induced Notch activation enhances the proliferation of human dental pulp cells by inhibiting autophagic flux.
Productive HBV infection of well-differentiated, hNTCP-expressing human hepatoma-derived (Huh7) cells.
Glucose potentiates β-cell function by inducing Tph1 expression in rat islets.
MicroRNA-200c impairs uterine receptivity formation by targeting FUT4 and α1,3-fucosylation.
MiR-616 promotes proliferation and inhibits apoptosis in glioma cells by suppressing expression of SOX7 via the Wnt signaling pathway.
Expression of PTEN-long mediated by CRISPR/Cas9 can repress U87 cell proliferation.
POSH participates in epileptogenesis by increasing the surface expression of the NMDA receptor: a promising therapeutic target for epilepsy.
The reproductive toxicology of male SD rats after PM2.5 exposure mediated by the stimulation of endoplasmic reticulum stress.
Autophagy is essential for flavopiridol‑induced cytotoxicity against MCF‑7 breast cancer cells.
Propofol regulates the expression of TLR4 through miR‑21 in human umbilical vein endothelial cells.
EPAC-RAP1 Axis-Mediated Switch in the Response of Primary and Metastatic Melanoma to Cyclic AMP.
Molecular mechanisms in vascular injury induced by hypertension: Expression and role of microRNA-34a.
Alginate enhances Toll-like receptor 4-mediated phagocytosis by murine RAW264.7 macrophages.
Biologico-clinical significance of DNMT3A variants expression in acute myeloid leukemia.
Upregulation of miR-126-3p promotes human saphenous vein endothelial cell proliferation in vitro and prevents vein graft neointimal formation ex vivo and in vivo.
A novel KCND3 mutation associated with early-onset lone atrial fibrillation.
EGFR expression in patients with stage III colorectal cancer after adjuvant chemotherapy and on cancer cell function.
Respiratory Syncytial Virus Nonstructural Protein 1 Blocks Glucocorticoid Receptor Nuclear Translocation by Targeting IPO13 and May Account for Glucocorticoid Insensitivity.
Interactions between GHRH and GABAARs in the brains of patients with epilepsy and in animal models of epilepsy.
Morin enhances hepatic Nrf2 expression in a liver fibrosis rat model.
ICAM-1 regulates macrophage polarization by suppressing MCP-1 expression via miR-124 upregulation.
Disruption of the c-Myc/miR-200b-3p/PRDX2 regulatory loop enhances tumor metastasis and chemotherapeutic resistance in colorectal cancer.
Bifunctional enzyme ATIC promotes propagation of hepatocellular carcinoma by regulating AMPK-mTOR-S6 K1 signaling.
Mammalian Numb protein antagonizes Notch by controlling postendocytic trafficking of the Notch ligand Delta-like 4.
Interleukin-22 participates in the inflammatory process of vitiligo.
HRD1 prevents apoptosis in renal tubular epithelial cells by mediating eIF2α ubiquitylation and degradation.
Human Cytomegalovirus Encoded miR-US25-1-5p Attenuates CD147/EMMPRIN-Mediated Early Antiviral Response.
Bisphenol a induces autophagy and apoptosis concurrently involving the Akt/mTOR pathway in testes of pubertal SD rats.
Looping-out mechanism for resolution of replicative stress at telomeres.
MicroRNA-149 contributes to scarless wound healing by attenuating inflammatory response.
Protective effect of lutein on ARPE-19 cells upon H2O2-induced G2/M arrest.
Intermedin improves cardiac function and sympathetic neural remodeling in a rat model of post myocardial infarction heart failure.
The effects of hyperoside on apoptosis and the expression of Fas/FasL and survivin in SW579 human thyroid squamous cell carcinoma cell line.
Treatment mechanism of matrine in combination with irinotecan for colon cancer.
HRS plays an important role for TLR7 signaling to orchestrate inflammation and innate immunity upon EV71 infection.
Calpain Inhibition Is Protective in Machado-Joseph Disease Zebrafish Due to Induction of Autophagy.
The impact of p53 on the early stage replication of retrovirus.
Platelet Derived Growth Factor Alpha (PDGFRα) Induces the Activation of Cardiac Fibroblasts by Activating c-Kit.
TIMELESS confers cisplatin resistance in nasopharyngeal carcinoma by activating the Wnt/β-catenin signaling pathway and promoting the epithelial mesenchymal transition.
CO-releasing molecules-2 attenuates ox-LDL-induced injury in HUVECs by ameliorating mitochondrial function and inhibiting Wnt/β-catenin pathway.
A Chinese herbal formula, Jian-Pi-Yi-Shen decoction, improves muscle atrophy via regulating mitochondrial quality control process in 5/6 nephrectomised rats.
Mediator MED23 Links Pigmentation and DNA Repair through the Transcription Factor MITF.
Activation of Nrf2/ARE signaling pathway attenuates lanthanum chloride induced injuries in primary rat astrocytes.
Seneca Valley Virus Suppresses Host Type I Interferon Production by Targeting Adaptor Proteins MAVS, TRIF, and TANK for Cleavage.
microRNA-451-modulated hnRNP A1 takes a part in granulocytic differentiation regulation and acute myeloid leukemia.
Neuronal zinc-α2-glycoprotein is decreased in temporal lobe epilepsy in patients and rats.
Flavonoid glycosides isolated from Epimedium brevicornum and their estrogen biosynthesis-promoting effects.
AMPK Serves as a Therapeutic Target Against Anemia of Inflammation.
Role of RAS/Wnt/β-catenin axis activation in the pathogenesis of podocyte injury and tubulo-interstitial nephropathy.
Transcription factor GATA3 expression is induced by GLS2 overexpression in a glioblastoma cell line but is GLS2-independent in patient-derived glioblastoma.
The role of metastasis-associated in colon cancer 1 (MACC1) in endometrial carcinoma tumorigenesis and progression.
Isoquercetin Ameliorates Cerebral Impairment in Focal Ischemia Through Anti-Oxidative, Anti-Inflammatory, and Anti-Apoptotic Effects in Primary Culture of Rat Hippocampal Neurons and Hippocampal CA1 Region of Rats.
The protective effect of dopamine on ventilator-induced lung injury via the inhibition of NLRP3 inflammasome.
Down-regulation of Pin1 in Temporal Lobe Epilepsy Patients and Mouse Model.
Protective effect of naringin against the LPS-induced apoptosis of PC12 cells: Implications for the treatment of neurodegenerative disorders.
miR-92a promotes tumor growth of osteosarcoma by targeting PTEN/AKT signaling pathway.
miR-30a radiosensitizes non-small cell lung cancer by targeting ATF1 that is involved in the phosphorylation of ATM.
Low expression of TMEM67 is a critical predictor of poor prognosis in human urothelial carcinoma of the bladder.
The Selective Serotonin Reuptake Inhibitor Fluoxetine Directly Inhibits Osteoblast Differentiation and Mineralization During Fracture Healing in Mice.
Interleukin 6 induces cell proliferation of clear cell renal cell carcinoma by suppressing hepaCAM via the STAT3-dependent up-regulation of DNMT1 or DNMT3b.
Histone deacetylase inhibitor apicidin increases expression of the α-secretase ADAM10 through transcription factor USF1-mediated mechanisms.
Blocking the recruitment of naive CD4+ T cells reverses immunosuppression in breast cancer.
Non-hemolytic enterotoxin of Bacillus cereus induces apoptosis in Vero cells.
Activation of ATP-sensitive potassium channel by iptakalim normalizes stress-induced HPA axis disorder and depressive behaviour by alleviating inflammation and oxidative stress in mouse hypothalamus.
GP73 represses host innate immune response to promote virus replication by facilitating MAVS and TRAF6 degradation.
Quercetin exerts preventive, ameliorative and prophylactic effects on cadmium chloride - induced oxidative stress in the uterus and ovaries of female Wistar rats.
Induction of pro-inflammatory genes by serum amyloid A1 in human amnion fibroblasts.
Bone marrow-derived mesenchymal stem cells (BMSCs) repair acute necrotized pancreatitis by secreting microRNA-9 to target the NF-κB1/p50 gene in rats.
HMGCS2 promotes autophagic degradation of the amyloid-β precursor protein through ketone body-mediated mechanisms.
Atorvastatin prevents Angiotensin II induced myocardial hypertrophy in vitro via CCAAT/enhancer-binding protein β.
DNA replication licensing factor Cdc6 and Plk4 kinase antagonistically regulate centrosome duplication via Sas-6.
CtBP2 overexpression promotes tumor cell proliferation and invasion in gastric cancer and is associated with poor prognosis.
Amelioration of amyloid-β-induced deficits by DcR3 in an Alzheimer's disease model.
Exenatide improves liver mitochondrial dysfunction and insulin resistance by reducing oxidative stress in high fat diet-induced obese mice.
Tumor necrosis factor receptor 2/AKT and ERK signaling pathways contribute to the switch from fibroblasts to CAFs by progranulin in microenvironment of colorectal cancer.
Satb2 Ablation Impairs Hippocampus-Based Long-Term Spatial Memory and Short-Term Working Memory and Immediate Early Genes (IEGs)-Mediated Hippocampal Synaptic Plasticity.
Identification, expression pattern and functional characterization of As-kip2 in diapause embryo restarting process of Artemia sinica.
In vitro biomimetic platforms featuring a perfusion system and 3D spheroid culture promote the construction of tissue-engineered corneal endothelial layers.
Knockdown of Sall4 inhibits intrahepatic cholangiocarcinoma cell migration and invasion in ICC-9810 cells.
Downregulating hypoxia-inducible factor-1α expression with perfluorooctyl-bromide nanoparticles reduces early brain injury following experimental subarachnoid hemorrhage in rats.
Down-regulation of long non-coding RNA FOXD3 antisense RNA 1 (FOXD3-AS1) inhibits cell proliferation, migration, and invasion in malignant glioma cells.
Upregulation of long non-coding RNA LINC00152 by SP1 contributes to gallbladder cancer cell growth and tumor metastasis via PI3K/AKT pathway.
Autophagy postpones apoptotic cell death in PRRSV infection through Bad-Beclin1 interaction.
Yin-Chen-Hao Tang Attenuates Severe Acute Pancreatitis in Rat: An Experimental Verification of In silico Network Target Prediction.
Exogenous Hydrogen Sulfide Attenuates High Glucose-Induced Cardiotoxicity by Inhibiting NLRP3 Inflammasome Activation by Suppressing TLR4/NF-κB Pathway in H9c2 Cells.
Parthenolide Induces Reactive Oxygen Species-Mediated Autophagic Cell Death in Human Osteosarcoma Cells.
FBXO6-Mediated Ubiquitination and Degradation of Ero1L Inhibits Endoplasmic Reticulum Stress-Induced Apoptosis.
Effect of Type I Diabetes on the Proteome of Mouse Oocytes.
Similar efficacy from specific and non-specific mineralocorticoid receptor antagonist treatment of muscular dystrophy mice.
N-Stearoyl-L-Tyrosine Inhibits the Senescence of Neural Stem/Progenitor Cells Induced by Aβ 1-42 via the CB2 Receptor.
Neurotrophic Effect of Adipose Tissue-Derived Stem Cells on Erectile Function Recovery by Pigment Epithelium-Derived Factor Secretion in a Rat Model of Cavernous Nerve Injury.
HIV-1 Tat Regulates Occludin and Aβ Transfer Receptor Expression in Brain Endothelial Cells via Rho/ROCK Signaling Pathway.
MiR-20a-5p represses multi-drug resistance in osteosarcoma by targeting the KIF26B gene.
Forsythoside A Inhibits BVDV Replication via TRAF2-Dependent CD28-4-1BB Signaling in Bovine PBMCs.
Finasteride Enhances the Generation of Human Myeloid-Derived Suppressor Cells by Up-Regulating the COX2/PGE2 Pathway.
Hepatitis B Virus Stimulated Fibronectin Facilitates Viral Maintenance and Replication through Two Distinct Mechanisms.
Electroacupuncture Promotes Remyelination after Cuprizone Treatment by Enhancing Myelin Debris Clearance.
Low-Dose Endothelial-Monocyte-Activating Polypeptide-II Induced Autophagy by Down-Regulating miR-20a in U-87 and U-251 Glioma Cells.
Fluoride induced endoplasmic reticulum stress and calcium overload in ameloblasts.
Effects of ZnO nanoparticles on perfluorooctane sulfonate induced thyroid-disrupting on zebrafish larvae.
Curcumin Attenuated Bupivacaine-Induced Neurotoxicity in SH-SY5Y Cells Via Activation of the Akt Signaling Pathway.
Evodiamine exerts anti-tumor effects against hepatocellular carcinoma through inhibiting β-catenin-mediated angiogenesis.
Angiopoietin-like protein 2 expression is suppressed by angiotensin II via the angiotensin II type 1 receptor in rat cardiomyocytes.
Simultaneous inhibition of the ubiquitin-proteasome system and autophagy enhances apoptosis induced by ER stress aggravators in human pancreatic cancer cells.
Alternative splicing of spleen tyrosine kinase differentially regulates colorectal cancer progression.
Structure-based discovery of two antiviral inhibitors targeting the NS3 helicase of Japanese encephalitis virus.
Regulation of PCGEM1 by p54/nrb in prostate cancer.
Epigenomic profiling of primary gastric adenocarcinoma reveals super-enhancer heterogeneity.
Control of cortex development by ULK4, a rare risk gene for mental disorders including schizophrenia.
Selenomethionine Ameliorates Neuropathology in the Olfactory Bulb of a Triple Transgenic Mouse Model of Alzheimer's Disease.
TDP-43 aggregation mirrors TDP-43 knockdown, affecting the expression levels of a common set of proteins.
TRIM52 inhibits Japanese Encephalitis Virus replication by degrading the viral NS2A.
Polyphenols from hawthorn peels and fleshes differently mitigate dyslipidemia, inflammation and oxidative stress in association with modulation of liver injury in high fructose diet-fed mice.
Reversal of cisplatin resistance in non-small cell lung cancer stem cells by Taxus chinensis var.
Triplex structures induce DNA double strand breaks via replication fork collapse in NER deficient cells.
miR-106a promotes cardiac hypertrophy by targeting mitofusin 2.
SIRT1 activator ameliorates the renal tubular injury induced by hyperglycemia in vivo and in vitro via inhibiting apoptosis.
Prognostic value of mixed lineage kinase domain-like protein expression in the survival of patients with gastric caner.
Neuroprotective Effects of Dexmedetomidine Against Hypoxia-Induced Nervous System Injury are Related to Inhibition of NF-κB/COX-2 Pathways.
Inhibition of Lysyl Oxidase by Cortisol Regeneration in Human Amnion: Implications for Rupture of Fetal Membranes.
Nanoparticle-facilitated autophagy inhibition promotes the efficacy of chemotherapeutics against breast cancer stem cells.
Long non-coding RNA H19 regulates FOXM1 expression by competitively binding endogenous miR-342-3p in gallbladder cancer.
Golgi protein 73 facilitates the interaction of hepatitis C virus NS5A with apolipoprotein E to promote viral particle secretion.
Dioscin attenuates gastric ischemia/reperfusion injury through the down-regulation of PKC/ERK1/2 signaling via PKCα and PKCβ2 inhibition.
Depletion of thymopoietin inhibits proliferation and induces cell cycle arrest/apoptosis in glioblastoma cells.
Afamin promotes glucose metabolism in papillary thyroid carcinoma.
Olig2-Targeted G-Protein-Coupled Receptor Gpr17 Regulates Oligodendrocyte Survival in Response to Lysolecithin-Induced Demyelination.
Cleavage and polyadenylation specific factor 4 targets NF-κB/cyclooxygenase-2 signaling to promote lung cancer growth and progression.
25-Hydroxycholesterol impairs endothelial function and vasodilation by uncoupling and inhibiting endothelial nitric oxide synthase.
Tim-4 protects mice against lipopolysaccharide-induced endotoxic shock by suppressing the NF-κB signaling pathway.
MicroRNA124 Regulated Neurite Elongation by Targeting OSBP.
Cyclooxygenase-2 is associated with malignant phenotypes in human lung cancer.
Sargassum fusiforme polysaccharides activate antioxidant defense by promoting Nrf2-dependent cytoprotection and ameliorate stress insult during aging.
Promotive effects of bone morphogenetic protein 2 on angiogenesis in hepatocarcinoma via multiple signal pathways.
NR4A1 Knockdown Suppresses Seizure Activity by Regulating Surface Expression of NR2B.
Quantitative proteomics reveals molecular mechanism of gamabufotalin and its potential inhibition on Hsp90 in lung cancer.
Keap1 hypomorphism protects against ischemic and obstructive kidney disease.
Lithium promotes DNA stability and survival of ischemic retinal neurocytes by upregulating DNA ligase IV.
microRNA-23a, -27a and -24 synergistically regulate JAK1/Stat3 cascade and serve as novel therapeutic targets in human acute erythroid leukemia.
Neutrophil extracellular traps are indirectly triggered by lipopolysaccharide and contribute to acute lung injury.
Activation of the RLR/MAVS Signaling Pathway by the L Protein of Mopeia Virus.
MicroRNA deep sequencing in two adult stem cell populations identifies miR-501 as a novel regulator of myosin heavy chain during muscle regeneration.
Phosphorylation of STAT2 on serine-734 negatively regulates the IFN-α-induced antiviral response.
17β-Estradiol Inhibites Tumor Necrosis Factor-α Induced Apoptosis of Human Nucleus Pulposus Cells via the PI3K/Akt Pathway.
Deletion of Pr130 Interrupts Cardiac Development in Zebrafish.
Downregulation of myosin VI reduced cell growth and increased apoptosis in human colorectal cancer.
Pristimerin overcomes adriamycin resistance in breast cancer cells through suppressing Akt signaling.
Downregulation of ATOH8 induced by EBV-encoded LMP1 contributes to the malignant phenotype of nasopharyngeal carcinoma.
MicroRNA-24 promotes 3T3-L1 adipocyte differentiation by directly targeting the MAPK7 signaling.
RBM4 promotes neuronal differentiation and neurite outgrowth by modulating Numb isoform expression.
CGP57380 enhances efficacy of RAD001 in non-small cell lung cancer through abrogating mTOR inhibition-induced phosphorylation of eIF4E and activating mitochondrial apoptotic pathway.
MiR-146a affects the alteration in myeloid differentiation induced by hydroquinone in human CD34+ hematopoietic progenitor cells and HL-60 cells.
Transcription factor Fli-1 positively regulates lipopolysaccharide-induced interleukin-27 production in macrophages.
Glutathione S-transferase SlGSTE1 in Spodoptera litura may be associated with feeding adaptation of host plants.
The protective effect of melatonin on smoke-induced vascular injury in rats and humans: a randomized controlled trial.
Akt inhibitor MK-2206 enhances the effect of cisplatin in gastric cancer cells.
Swine TRIM21 restricts FMDV infection via an intracellular neutralization mechanism.
Significance of the NOR1-FOXA1/HDAC2-Slug regulatory network in epithelial-mesenchymal transition of tumor cells.
Bromodomain-containing protein 7 (BRD7) as a potential tumor suppressor in hepatocellular carcinoma.
TGF-β1 activates the canonical NF-κB signaling to promote cell survival and proliferation in dystrophic muscle fibroblasts in vitro.
REST alleviates neurotoxic prion peptide-induced synaptic abnormalities, neurofibrillary degeneration and neuronal death partially via LRP6-mediated Wnt-β-catenin signaling.
Suppression of prostate cancer progression by cancer cell stemness inhibitor napabucasin.
A novel conditional gene silencing method using a tumor-specific and heat-inducible siRNA system.
Mitigation of tight junction protein dysfunction in lung microvascular endothelial cells with pitavastatin.
Oleanolic acid inhibits cell survival and proliferation of prostate cancer cells in vitro and in vivo through the PI3K/Akt pathway.
Recombinant adeno-associated virus-delivered anginex inhibits angiogenesis and growth of HUVECs by regulating the Akt, JNK and NF-κB signaling pathways.
Coordinate regulatory osteogenesis effects of icariin, timosaponin B II and ferulic acid from traditional Chinese medicine formulas on UMR-106 osteoblastic cells and osteoblasts in neonatal rat calvaria cultures.
Downregulation of stathmin 1 in human gallbladder carcinoma inhibits tumor growth in vitro and in vivo.
HuR-regulated lncRNA NEAT1 stability in tumorigenesis and progression of ovarian cancer.
Midgut epithelium in molting silkworm: A fine balance among cell growth, differentiation, and survival.
High TXNDC5 expression predicts poor prognosis in renal cell carcinoma.
MicroRNA-124 negatively regulates LPS-induced TNF-α production in mouse macrophages by decreasing protein stability.
Berberine in combination with cisplatin suppresses breast cancer cell growth through induction of DNA breaks and caspase-3-dependent apoptosis.
Malignant gliomas induce and exploit astrocytic mesenchymal-like transition by activating canonical Wnt/β-catenin signaling.
Comparative Effects of Bile Diversion and Duodenal-Jejunal Bypass on Glucose and Lipid Metabolism in Male Diabetic Rats.
Influence of orally fed a select mixture of Bacillus probiotics on intestinal T-cell migration in weaned MUC4 resistant pigs following Escherichia coli challenge.
Persisting and Increasing Neutrophil Infiltration Associates with Gastric Carcinogenesis and E-cadherin Downregulation.
Polyhydroxycurcuminoids but not curcumin upregulate neprilysin and can be applied to the prevention of Alzheimer's disease.
Homologous recombination-dependent repair of telomeric DSBs in proliferating human cells.
Total saponins isolated from Radix et Rhizoma Leonticis suppresses tumor cells growth by regulation of PI3K/Akt/mTOR and p38 MAPK pathways.
Loss of TIM50 suppresses proliferation and induces apoptosis in breast cancer.
Knockdown of protein phosphatase 5 inhibits ovarian cancer growth in vitro.
DNA Methylation mediated down-regulating of MicroRNA-33b and its role in gastric cancer.
Regulation of SCN3B/scn3b by Interleukin 2 (IL-2): IL-2 modulates SCN3B/scn3b transcript expression and increases sodium current in myocardial cells.
miR-183 regulates autophagy and apoptosis in colorectal cancer through targeting of UVRAG.
A simple multi-well stretching device to induce inflammatory responses of vascular endothelial cells.
Differential requirement of bone morphogenetic protein receptors Ia (ALK3) and Ib (ALK6) in early embryonic patterning and neural crest development.
Increased expression of copine VI in patients with refractory epilepsy and a rat model.
Ginsenoside Rg3 inhibits epithelial-mesenchymal transition (EMT) and invasion of lung cancer by down-regulating FUT4.
A novel combination of oridonin and valproic acid in enhancement of apoptosis induction of HL-60 leukemia cells.
Effect of LYRM1 knockdown on proliferation, apoptosis, differentiation and mitochondrial function in the P19 cell model of cardiac differentiation in vitro.
NudC regulates actin dynamics and ciliogenesis by stabilizing cofilin 1.
Role of KIF2A in the progression and metastasis of human glioma.
Nanocomplexes from RGD-modified generation 1.0 polyamidoamine based copolymers used for intravascular gene release to prevent restenosis.
PGRN promotes migration and invasion of epithelial ovarian cancer cells through an epithelial mesenchymal transition program and the activation of cancer associated fibroblasts.
CREB-binding protein regulates lung cancer growth by targeting MAPK and CPSF4 signaling pathway.
MicroRNA-372 inhibits endometrial carcinoma development by targeting the expression of the Ras homolog gene family member C (RhoC).
RNF135, RING finger protein, promotes the proliferation of human glioblastoma cells in vivo and in vitro via the ERK pathway.
Decreased TPD52 expression is associated with poor prognosis in primary hepatocellular carcinoma.
Thrombospondin-1 might be a therapeutic target to suppress RB cells by regulating the DNA double-strand breaks repair.
Lactobacillus rhamnosus GR-1 Ameliorates Escherichia coli-Induced Inflammation and Cell Damage via Attenuation of ASC-Independent NLRP3 Inflammasome Activation.
DLX3 negatively regulates osteoclastic differentiation through microRNA-124.
Mammalian cells lacking either the cotranslational or posttranslocational oligosaccharyltransferase complex display substrate-dependent defects in asparagine linked glycosylation.
Effects of total flavonoids from Drynariae Rhizoma prevent bone loss in vivo and in vitro.
Life-cycle exposure to BDE-47 results in thyroid endocrine disruption to adults and offsprings of zebrafish (Danio rerio).
Angelicin inhibits human lung carcinoma A549 cell growth and migration through regulating JNK and ERK pathways.
Developmental regulation of CYP3A4 and CYP3A7 in Chinese Han population.
The lncRNA MALAT1 functions as a competing endogenous RNA to regulate MCL-1 expression by sponging miR-363-3p in gallbladder cancer.
Oligosaccharyltransferase inhibition induces senescence in RTK-driven tumor cells.
Interaction between endogenous carbon monoxide and hydrogen sulfide in the mechanism of gastroprotection against acute aspirin-induced gastric damage.
Vam3 ameliorates total body irradiation-induced hematopoietic system injury partly by regulating the expression of Nrf2-targeted genes.
Repression of CDKN2C caused by PML/RARα binding promotes the proliferation and differentiation block in acute promyelocytic leukemia.
Senescence: novel insight into DLX3 mutations leading to enhanced bone formation in Tricho-Dento-Osseous syndrome.
Rab8a/Rab11a regulate intercellular communications between neural cells via tunneling nanotubes.
Elevated expression of ZNF217 promotes prostate cancer growth by restraining ferroportin-conducted iron egress.
Unc-5 homolog B (UNC5B) is one of the key downstream targets of N-α-Acetyltransferase 10 (Naa10).
Up-regulation of granzyme B and perforin by staphylococcal enterotoxin C2 mutant induces enhanced cytotoxicity in Hepa1-6 cells.
Attribution of NKG2DL to the inhibition of early stage allogeneic tumors in mice.
ERK-mediated NF-κB activation through ASIC1 in response to acidosis.
Growth Differentiation Factor-15-Induced Contractile Activity and Extracellular Matrix Production in Human Trabecular Meshwork Cells.
Myeloid cells are capable of synthesizing aldosterone to exacerbate damage in muscular dystrophy.
Exercise preconditioning reduces neonatal incision surgery-induced enhanced hyperalgesia via inhibition of P38 mitogen-activated protein kinase and IL-1β, TNF-α release.
Low level of FOXL1 indicates a worse prognosis for gastric cancer patients.
Dynamic distributions of tumor necrosis factor-alpha and its receptors in the red nucleus of rats with spared nerve injury.
LINE-1 gene hypomethylation and p16 gene hypermethylation in HepG2 cells induced by low-dose and long-term triclosan exposure: The role of hydroxyl group.
Improvements of Glucose and Lipid Metabolism After Jejuno-ileal Circuit Procedure in a Non-obese Diabetic Rat Model.
NRAGE is involved in homologous recombination repair to resist the DNA-damaging chemotherapy and composes a ternary complex with RNF8-BARD1 to promote cell survival in squamous esophageal tumorigenesis.
Inhibition of the glucocorticoid receptor results in an enhanced miR-99a/100-mediated radiation response in stem-like cells from human prostate cancers.
Paper-based microreactor array for rapid screening of cell signaling cascades.
The long noncoding RNA ASNR regulates degradation of Bcl-2 mRNA through its interaction with AUF1.
Porcine reproductive and respiratory syndrome virus triggers mitochondrial fission and mitophagy to attenuate apoptosis.
Long non-coding RNA AFAP1-AS1 facilitates tumor growth and promotes metastasis in colorectal cancer.
EWSR1 regulates mitosis by dynamically influencing microtubule acetylation.
USP14 regulates autophagy by suppressing K63 ubiquitination of Beclin 1.
Constitutive translation of human α-synuclein is mediated by the 5'-untranslated region.
Upregulation of GSK3β Contributes to Brain Disorders in Elderly REGγ-knockout Mice.
Interplay of autophagy and apoptosis during PRRSV infection of Marc145 cell.
Down-regulation of ribosomal protein S15A inhibits proliferation of human glioblastoma cells in vivo and in vitro via AKT pathway.
Lead Inhibits Human Sperm Functions by Reducing the Levels of Intracellular Calcium, cAMP, and Tyrosine Phosphorylation.
Altered expression of miR-125a-5p in thymoma-associated myasthenia gravis and its down-regulation of foxp3 expression in Jurkat cells.
Lentivirus-mediated knockdown of CTDP1 inhibits lung cancer cell growth in vitro.
Downregulation of VEGF and upregulation of TL1A expression induce HUVEC apoptosis in response to high glucose stimuli.
β-Arrestins promote podocyte injury by inhibition of autophagy in diabetic nephropathy.
Linc-RoR promotes c-Myc expression through hnRNP I and AUF1.
Inhibition on Apoptosis Induced by Elevated Hydrostatic Pressure in Retinal Ganglion Cell-5 via Laminin Upregulating β1-integrin/Focal Adhesion Kinase/Protein Kinase B Signaling Pathway.
Autocrine Sonic hedgehog signaling promotes gastric cancer proliferation through induction of phospholipase Cγ1 and the ERK1/2 pathway.
A Point Mutation in the Exon Junction Complex Factor Y14 Disrupts Its Function in mRNA Cap Binding and Translation Enhancement.
Comparative proteomic study of the response to hypoxia in the muscle of oriental river prawn (Macrobrachium nipponense).
PACE4 regulates apoptosis in human prostate cancer cells via endoplasmic reticulum stress and mitochondrial signaling pathways.
Trefoil factor 1 elevates the malignant phenotype of mucinous ovarian cancer cell through Wnt/β-catenin signaling.
Complement factors C1q, C3 and C5b-9 in the posterior sclera of guinea pigs with negative lens-defocused myopia.
Regulative Effect of Nampt on Tumor Progression and Cell Viability in Human Colorectal Cancer.
Highly expressed UNC119 promotes hepatocellular carcinoma cell proliferation through Wnt/β-catenin signaling and predicts a poor prognosis.
Huaier Aqueous Extract Induces Hepatocellular Carcinoma Cells Arrest in S Phase via JNK Signaling Pathway.
A Selected Lactobacillus rhamnosus Strain Promotes EGFR-Independent Akt Activation in an Enterotoxigenic Escherichia coli K88-Infected IPEC-J2 Cell Model.
Down-Regulation of NDUFB9 Promotes Breast Cancer Cell Proliferation, Metastasis by Mediating Mitochondrial Metabolism.
Effects of Carbon Nanotube Environmental Dispersion on an Aquatic Invertebrate, Hirudo medicinalis.
CRISPR/Cas9 Promotes Functional Study of Testis Specific X-Linked Gene In Vivo.
Endothelial cell-targeted pVEGF165 polyplex plays a pivotal role in inhibiting intimal thickening after vascular injury.
Circulating microparticles from patients with valvular heart disease and cardiac surgery inhibit endothelium-dependent vasodilation.
Effect of Huaier on the proliferation and apoptosis of human gastric cancer cells through modulation of the PI3K/AKT signaling pathway.
Phase transition of spindle-associated protein regulate spindle apparatus assembly.
SUMOylation at K707 of DGCR8 controls direct function of primary microRNA.
Prosaposin facilitates sortilin-independent lysosomal trafficking of progranulin.
Identification of cellular microRNA-136 as a dual regulator of RIG-I-mediated innate immunity that antagonizes H5N1 IAV replication in A549 cells.
Protein kinase CK2α catalytic subunit is overexpressed and serves as an unfavorable prognostic marker in primary hepatocellular carcinoma.
FGF1-FGFR1 axis promotes tongue squamous cell carcinoma (TSCC) metastasis through epithelial-mesenchymal transition (EMT).
BPTF promotes tumor growth and predicts poor prognosis in lung adenocarcinomas.
Neuroleukin/Autocrine Motility Factor Receptor Pathway Promotes Proliferation of Articular Chondrocytes through Activation of AKT and Smad2/3.
RanGTP aids anaphase entry through Ubr5-mediated protein turnover.
FOXL2 down-regulates vitellogenin expression at mature stage in Eriocheir sinensis.
G-protein-coupled receptor 137 accelerates proliferation of urinary bladder cancer cells in vitro.
MiR542-3p Regulates the Epithelial-Mesenchymal Transition by Directly Targeting BMP7 in NRK52e.
Phosphorylation and activation of ubiquitin-specific protease-14 by Akt regulates the ubiquitin-proteasome system.
Encephalomyocarditis Virus 3C Protease Relieves TRAF Family Member-associated NF-κB Activator (TANK) Inhibitory Effect on TRAF6-mediated NF-κB Signaling through Cleavage of TANK.
Co-expression of mitosis-regulating genes contributes to malignant progression and prognosis in oligodendrogliomas.
Dental Abnormalities Caused by Novel Compound Heterozygous CTSK Mutations.
Vav3 oncogene is upregulated and a poor prognostic factor in breast cancer patients.
Microgravity activates p38 MAPK-C/EBPβ pathway to regulate the expression of arginase and inflammatory cytokines in macrophages.
Mitosis. Microtubule detyrosination guides chromosomes during mitosis.
HAP1 helps to regulate actin-based transport of insulin-containing granules in pancreatic β cells.
MNRR1 (formerly CHCHD2) is a bi-organellar regulator of mitochondrial metabolism.
Proteomic profile in Perna viridis after exposed to Prorocentrum lima, a dinoflagellate producing DSP toxins.
DNA methylation downregulated mir-10b acts as a tumor suppressor in gastric cancer.
Toward operative in vivo fluorescence imaging of the c-Met proto-oncogene for personalization of therapy in ovarian cancer.
Lentivirus-mediated silencing of SCIN inhibits proliferation of human lung carcinoma cells.
Novel function of PITH domain-containing 1 as an activator of internal ribosomal entry site to enhance RUNX1 expression and promote megakaryocyte differentiation.
Annexin A3 as a potential target for immunotherapy of liver cancer stem-like cells.
Human mammary microenvironment better regulates the biology of human breast cancer in humanized mouse model.
Potent effects of the total saponins from Dioscorea nipponica Makino against streptozotocin-induced type 2 diabetes mellitus in rats.
Moesin and myosin phosphatase confine neutrophil orientation in a chemotactic gradient.
Targeting non-coding RNAs with the CRISPR/Cas9 system in human cell lines.
The Energy Metabolism in Caenorhabditis elegans under The Extremely Low-Frequency Electromagnetic Field Exposure.
Flavivirus Infection Impairs Peroxisome Biogenesis and Early Antiviral Signaling.
Erythropoietin Protects Retinal Cells in Diabetic Rats Through Upregulating ZnT8 via Activating ERK Pathway and Inhibiting HIF-1α Expression.
Tumor necrosis factor α induces myofibroblast differentiation in human tongue cancer and promotes invasiveness and angiogenesis via secretion of stromal cell-derived factor-1.
Protection of seven dibenzocyclooctadiene lignans from Schisandra chinensis against serum and glucose deprivation injury in SH-SY5Y cells.
Cancer-testis antigen MAGE-C2 binds Rbx1 and inhibits ubiquitin ligase-mediated turnover of cyclin E.
MicroRNA-186 induces sensitivity of ovarian cancer cells to paclitaxel and cisplatin by targeting ABCB1.
The Mediator subunit MED23 couples H2B mono-ubiquitination to transcriptional control and cell fate determination.
Involvement of AMPK/SIRT1 pathway in anti-allodynic effect of troxerutin in CCI-induced neuropathic pain.
miRNA-204 drives cardiomyocyte proliferation via targeting Jarid2.
Genipin inhibits NLRP3 and NLRC4 inflammasome activation via autophagy suppression.
Activation of AMPK restricts coxsackievirus B3 replication by inhibiting lipid accumulation.
CXCR1/2 antagonism with CXCL8/Interleukin-8 analogue CXCL8(3-72)K11R/G31P restricts lung cancer growth by inhibiting tumor cell proliferation and suppressing angiogenesis.
The Antiviral Effect of Baicalin on Enterovirus 71 In Vitro.
Cdc42-Interacting Protein 4 Represses E-Cadherin Expression by Promoting β-Catenin Translocation to the Nucleus in Murine Renal Tubular Epithelial Cells.
si-RNA-mediated knockdown of PDLIM5 suppresses gastric cancer cell proliferation in vitro.
DNA methylation regulates bromodomain-containing protein 2 expression during adipocyte differentiation.
Ppm1b negatively regulates necroptosis through dephosphorylating Rip3.
GSK3β-Dzip1-Rab8 cascade regulates ciliogenesis after mitosis.
MicroRNA‑133b inhibits connective tissue growth factor in colorectal cancer and correlates with the clinical stage of the disease.
Modification of BECN1 by ISG15 plays a crucial role in autophagy regulation by type I IFN/interferon.
The tumor suppressor role of miR-124 in osteosarcoma.
Megakaryocytic differentiation of K562 cells induced by PMA reduced the activity of respiratory chain complex IV.
MicroRNA-424 is down-regulated in hepatocellular carcinoma and suppresses cell migration and invasion through c-Myb.
The self-interaction of a nodavirus replicase is enhanced by mitochondrial membrane lipids.
Leptin downregulates aggrecan through the p38-ADAMST pathway in human nucleus pulposus cells.
MicroRNA-217 regulates WASF3 expression and suppresses tumor growth and metastasis in osteosarcoma.
MicroRNA-10a is down-regulated by DNA methylation and functions as a tumor suppressor in gastric cancer cells.
Sox9 regulates hyperexpression of Wnt1 and Fzd1 in human osteosarcoma tissues and cells.
Expression of leucine aminopeptidase 3 (LAP3) correlates with prognosis and malignant development of human hepatocellular carcinoma (HCC).
SERPINA3 promotes endometrial cancer cells growth by regulating G2/M cell cycle checkpoint and apoptosis.
Gemcitabine resistance in breast cancer cells regulated by PI3K/AKT-mediated cellular proliferation exerts negative feedback via the MEK/MAPK and mTOR pathways.
Distinct Orai-coupling domains in STIM1 and STIM2 define the Orai-activating site.
Production of transgenic pigs over-expressing the antiviral gene Mx1.
Type 2 diabetes mellitus control and atherosclerosis prevention in a non-obese rat model using duodenal-jejunal bypass.
High density lipoprotein from patients with valvular heart disease uncouples endothelial nitric oxide synthase.
Neuroprotective effect of schizandrin A on oxygen and glucose deprivation/reperfusion-induced cell injury in primary culture of rat cortical neurons.
Altered expression of hypoxia-Inducible factor-1α participates in the epileptogenesis in animal models.
Regulation of silicosis formation by lysophosphatidic acid and its receptors.
MicroRNA-217 functions as a tumour suppressor gene and correlates with cell resistance to cisplatin in lung cancer.
Regulation of COX-2 expression by miR-146a in lung cancer cells.
SILAC-based quantitative proteomic analysis of secretome between activated and reverted hepatic stellate cells.
Dioscin attenuates hepatic ischemia-reperfusion injury in rats through inhibition of oxidative-nitrative stress, inflammation and apoptosis.
Hypoxia-inducible factor 1α mediates neuroprotection of hypoxic postconditioning against global cerebral ischemia.
Nardilysin-dependent proteolysis of cell-associated VTCN1 (B7-H4) marks type 1 diabetes development.
CKIP-1 suppresses the adipogenesis of mesenchymal stem cells by enhancing HDAC1-associated repression of C/EBPα.
Suppression of toll-like receptor 2 expression inhibits the bioactivity of human hepatocellular carcinoma.
PP242 synergizes with suberoylanilide hydroxamic acid to inhibit growth of ovarian cancer cells.
The involvement of CXCR7 in modulating the progression of papillary thyroid carcinoma.
Up-regulation of hexokinase1 in the right ventricle of monocrotaline induced pulmonary hypertension.
MicroRNA-188 suppresses G1/S transition by targeting multiple cyclin/CDK complexes.
Elevated autocrine EDIL3 protects hepatocellular carcinoma from anoikis through RGD-mediated integrin activation.
Down-regulation of asparagine synthetase induces cell cycle arrest and inhibits cell proliferation of breast cancer.
Rho/Rock cross-talks with transforming growth factor-β/Smad pathway participates in lung fibroblast-myofibroblast differentiation.
TBC1D9B functions as a GTPase-activating protein for Rab11a in polarized MDCK cells.
Effects of the total saponins from Rosa laevigata Michx fruit against acetaminophen-induced liver damage in mice via induction of autophagy and suppression of inflammation and apoptosis.
Nasopharyngeal cancer-specific therapy based on fusion peptide-functionalized lipid nanoparticles.
Effect of nigranoic acid on Ca²⁺ influx and its downstream signal mechanism in NGF-differentiated PC12 cells.
Molecular characterization and expression analysis of the autophagic gene beclin 1 from the purse red common carp (Cyprinus carpio) exposed to cadmium.
miR-21 promotes human nucleus pulposus cell proliferation through PTEN/AKT signaling.
Novel function of the chromosome 7 open reading frame 41 gene to promote leukemic megakaryocyte differentiation by modulating TPA-induced signaling.
Molecular analysis of curcumin-induced polarization of murine RAW264.7 macrophages.
The roles of p38 MAPK/MSK1 signaling pathway in the neuroprotection of hypoxic postconditioning against transient global cerebral ischemia in adult rats.
MGARP regulates mouse neocortical development via mitochondrial positioning.
HepaCAM inhibits clear cell renal carcinoma 786-0 cell proliferation via blocking PKCε translocation from cytoplasm to plasma membrane.
p16 Methylation is associated with chemosensitivity to fluorouracil in patients with advanced gastric cancer.
Negative association of R-Ras activation and breast cancer development.
Toxoplasma gondii inhibits apoptosis via a novel STAT3-miR-17-92-Bim pathway in macrophages.
Activation of JNK1/2 and p38 MAPK signaling pathways promotes enterovirus 71 infection in immature dendritic cells.
Oxidored-nitro domain containing protein 1 (NOR1) expression suppresses slug/vimentin but not snail in nasopharyngeal carcinoma: Inhibition of EMT in vitro and in vivo in mice.
KIF2A silencing inhibits the proliferation and migration of breast cancer cells and correlates with unfavorable prognosis in breast cancer.
Mulberroside A protects against ischemic impairment in primary culture of rat cortical neurons after oxygen-glucose deprivation followed by reperfusion.
LPS induced miR-181a promotes pancreatic cancer cell migration via targeting PTEN and MAP2K4.
Regulated intramembrane proteolysis of the frontotemporal lobar degeneration risk factor, TMEM106B, by signal peptide peptidase-like 2a (SPPL2a).
The inhibitory effect of IFN-γ on protease HTRA1 expression in rheumatoid arthritis.
Neuroprotection by (-)-epigallocatechin-3-gallate in a rat model of stroke is mediated through inhibition of endoplasmic reticulum stress.
Microgravity inhibition of lipopolysaccharide-induced tumor necrosis factor-α expression in macrophage cells.
iTRAQ-based proteomic analysis of dioscin on human HCT-116 colon cancer cells.
Dengue virus subgenomic RNA induces apoptosis through the Bcl-2-mediated PI3k/Akt signaling pathway.
Long non-coding RNA UCA1 promotes breast tumor growth by suppression of p27 (Kip1).
High glucose induces activation of the local renin‑angiotensin system in glomerular endothelial cells.
Pretreatment of mice with oligonucleotide prop5 protects them from influenza virus infections.
Akt/Ezrin Tyr353/NF-κB pathway regulates EGF-induced EMT and metastasis in tongue squamous cell carcinoma.
A microtubule-associated zinc finger protein, BuGZ, regulates mitotic chromosome alignment by ensuring Bub3 stability and kinetochore targeting.
An alternative splicing isoform of MITA antagonizes MITA-mediated induction of type I IFNs.
Protein profiling the differences between diabetic and normal mouse cumulus cells.
Levofloxacin increases the effect of serum deprivation on anoikis of rat nucleus pulposus cells via Bax/Bcl-2/caspase-3 pathway.
Differential effects of agonistic 4-1BB (CD137) monoclonal antibody on the maturation and functions of hypoxic dendritic cells.
Effects of sodium fluoride treatment in vitro on cell proliferation, BMP-2 and BMP-3 expression in human osteosarcoma MG-63 cells.
A recessive variant of XRCC4 predisposes to non- BRCA1/2 breast cancer in chinese women and impairs the DNA damage response via dysregulated nuclear localization.
Calreticulin promotes migration and invasion of esophageal cancer cells by upregulating neuropilin-1 expression via STAT5A.
Decreased expression of TRIM3 is associated with poor prognosis in patients with primary hepatocellular carcinoma.
Potent effects of flavonoid-rich extract from Rosa laevigata Michx fruit against hydrogen peroxide-induced damage in PC12 cells via attenuation of oxidative stress, inflammation and apoptosis.
microRNA 490-3P enhances the drug-resistance of human ovarian cancer cells.
DNA methylation-mediated silencing of matricellular protein dermatopontin promotes hepatocellular carcinoma metastasis by α3β1 integrin-Rho GTPase signaling.
Oxidoreductase activity is necessary for N-glycosylation of cysteine-proximal acceptor sites in glycoproteins.
Puerarin protected the brain from cerebral ischemia injury via astrocyte apoptosis inhibition.
The role of SIRT6 in the differentiation of vascular smooth muscle cells in response to cyclic strain.
A synergic role of caspase-6 and caspase-3 in Tau truncation at D421 induced by H2O 2.
Protective effects of the total saponins from Dioscorea nipponica Makino against carbon tetrachloride-induced liver injury in mice through suppression of apoptosis and inflammation.
Sine oculis homeobox homolog 1 promotes α5β1-mediated invasive migration and metastasis of cervical cancer cells.
Umbilical cord blood cells regulate the differentiation of endogenous neural stem cells in hypoxic ischemic neonatal rats via the hedgehog signaling pathway.
IKKα restoration via EZH2 suppression induces nasopharyngeal carcinoma differentiation.
Cadmium induces liver cell apoptosis through caspase-3A activation in purse red common carp (Cyprinus carpio).
MicroRNA-10b promotes nucleus pulposus cell proliferation through RhoC-Akt pathway by targeting HOXD10 in intervetebral disc degeneration.
Simvastatin alleviates hyperpermeability of glomerular endothelial cells in early-stage diabetic nephropathy by inhibition of RhoA/ROCK1.
Identification of three antiviral inhibitors against Japanese encephalitis virus from library of pharmacologically active compounds 1280.
Resolvin D1 reverts lipopolysaccharide-induced TJ proteins disruption and the increase of cellular permeability by regulating IκBα signaling in human vascular endothelial cells.
Anti-miRNA-23a oligonucleotide suppresses glioma cells growth by targeting apoptotic protease activating factor-1.
Proteomic studies of multiple myeloma in RPMI8226 cell line treated with bendamustine.
Differential roles of C-terminal Eps15 homology domain proteins as vesiculators and tubulators of recycling endosomes.
Molecular cloning, immunohistochemical localization, characterization and expression analysis of caspase-9 from the purse red common carp (Cyprinus carpio) exposed to cadmium.
Lipopolysaccharide increases the incidence of collagen-induced arthritis in mice through induction of protease HTRA-1 expression.
Effects of perchlorate on BDE-47-induced alteration thyroid hormone and gene expression of in the hypothalamus-pituitary-thyroid axis in zebrafish larvae.
MicroRNA-124 mediates the cholinergic anti-inflammatory action through inhibiting the production of pro-inflammatory cytokines.
Synergistic anti-glioma effect of Hydroxygenkwanin and Apigenin in vitro.
Amyloid-β(1-42) oligomer accelerates senescence in adult hippocampal neural stem/progenitor cells via formylpeptide receptor 2.
Fructose-1,6-bisphosphatase, Malate Dehydrogenase, Isocitrate Lyase, Phosphoenolpyruvate Carboxykinase, Glyceraldehyde-3-phosphate Dehydrogenase, and Cyclophilin A are secreted in Saccharomyces cerevisiae grown in low glucose.
Protection of the flavonoid fraction from Rosa laevigata Michx fruit against carbon tetrachloride-induced acute liver injury in mice.
PPE38 of Mycobacterium marinum triggers the cross-talk of multiple pathways involved in the host response, as revealed by subcellular quantitative proteomics.
Inositol-requiring protein 1α signaling pathway is activated in the temporal cortex of patients with mesial temporal lobe epilepsy.
Salidroside protects against hydrogen peroxide-induced injury in HUVECs via the regulation of REDD1 and mTOR activation.
c-Src regulates cell cycle proteins expression through protein kinase B/glycogen synthase kinase 3 beta and extracellular signal-regulated kinases 1/2 pathways in MCF-7 cells.
Identification of STAT2 serine 287 as a novel regulatory phosphorylation site in type I interferon-induced cellular responses.
INMAP, a novel truncated version of POLR3B, represses AP-1 and p53 transcriptional activity.
Hyperforin attenuates brain damage induced by transient middle cerebral artery occlusion (MCAO) in rats via inhibition of TRPC6 channels degradation.
PES1 regulates sensitivity of colorectal cancer cells to anticancer drugs.
Neuroprotective effect of calcitriol on ischemic/reperfusion injury through the NR3A/CREB pathways in the rat hippocampus.
Isoquercetin protects cortical neurons from oxygen-glucose deprivation-reperfusion induced injury via suppression of TLR4-NF-кB signal pathway.
Cadmium triggers kidney cell apoptosis of purse red common carp (Cyprinus carpio) without caspase-8 activation.
STAT3-dependent transactivation of miRNA genes following Toxoplasma gondii infection in macrophage.
miR-133b, a muscle-specific microRNA, is a novel prognostic marker that participates in the progression of human colorectal cancer via regulation of CXCR4 expression.
Effects of flavonoids from Rosa laevigata Michx fruit against high-fat diet-induced non-alcoholic fatty liver disease in rats.
Neuroprotectin D1 attenuates brain damage induced by transient middle cerebral artery occlusion in rats through TRPC6/CREB pathways.
Induction of apoptosis in infantile hemangioma endothelial cells by propranolol.
Lumbrokinase attenuates diabetic nephropathy through regulating extracellular matrix degradation in Streptozotocin-induced diabetic rats.
Vps34p is required for the decline of extracellular fructose-1,6-bisphosphatase in the vacuole import and degradation pathway.
The p16-specific reactivation and inhibition of cell migration through demethylation of CpG islands by engineered transcription factors.
Phosphatase of regenerating liver-3 directly interacts with integrin β1 and regulates its phosphorylation at tyrosine 783.
miR-129-3p controls cilia assembly by regulating CP110 and actin dynamics.
Embryonic liver fodrin involved in hepatic stellate cell activation and formation of regenerative nodule in liver cirrhosis.
A novel mouse model of gastric cancer with human gastric microenvironment.
β-2 spectrin is involved in hepatocyte proliferation through the interaction of TGFβ/Smad and PI3K/AKT signalling.
Genetic and epigenetic control of UNC5C expression in human renal cell carcinoma.
SCFFBXL¹⁵ regulates BMP signalling by directing the degradation of HECT-type ubiquitin ligase Smurf1.
Transplanted olfactory ensheathing cells reduce the gliotic injury response of Müller cells in a rat model of retinitis pigmentosa.
Differentiation of human bone marrow mesenchymal stem cells into neuron-like cells in vitro.
Fabp3 inhibits proliferation and promotes apoptosis of embryonic myocardial cells.
Differential expression of microRNAs in cardiac myocytes compared to undifferentiated P19 cells.
Involvement of IRE1α signaling in the hippocampus in patients with mesial temporal lobe epilepsy.
Differential proteome analysis of bone marrow mesenchymal stem cells from adolescent idiopathic scoliosis patients.
Functional characterization of inward rectifier potassium ion channel in murine fetal ventricular cardiomyocytes.
Alpha1,3 fucosyltransferase VII plays a role in colorectal carcinoma metastases by promoting the carbohydration of glycoprotein CD24.
Inhibition of epithelial to mesenchymal transition in metastatic breast carcinoma cells by c-Src suppression.
The role of enoyl-CoA hydratase short chain 1 and peroxiredoxin 3 in PP2-induced apoptosis in human breast cancer MCF-7 cells.
SZ-685C, a marine anthraquinone, is a potent inducer of apoptosis with anticancer activity by suppression of the Akt/FOXO pathway.
Epidermal growth factor stimulates human trophoblast cell migration through Rho A and Rho C activation.
Electrophysiological study on differentiation of rat bone marrow stromal stem cells into neuron-like cells in vitro by edaravone.
Palladin is overexpressed in the non-neoplastic stroma of infiltrating ductal adenocarcinomas of the pancreas, but is only rarely overexpressed in neoplastic cells.
Chen J, Zhu H, Zhu Y, Zhao C, Wang S, Zheng Y, Xie Z, Jin Y, Song H, Yang L, Zhang J, Dai J, Hu Z, Wang H
Bioactive materials 2022 Mar;9:29-43
Bioactive materials 2022 Mar;9:29-43
Isoxanthohumol, a component of Sophora flavescens, promotes the activation of the NLRP3 inflammasome and induces idiosyncratic hepatotoxicity.
Lin L, Chen Y, Li Q, Xu G, Ding K, Ren L, Shi W, Wang Y, Li Z, Dai W, Wei Z, Yang Y, Bai Z, Xiao X
Journal of ethnopharmacology 2022 Mar 1;285:114796
Journal of ethnopharmacology 2022 Mar 1;285:114796
H. pylori CagA activates the NLRP3 inflammasome to promote gastric cancer cell migration and invasion.
Zhang X, Li C, Chen D, He X, Zhao Y, Bao L, Wang Q, Zhou J, Xie Y
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2022 Jan;71(1):141-155
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2022 Jan;71(1):141-155
Increased m6A-RNA methylation and FTO suppression is associated with myocardial inflammation and dysfunction during endotoxemia in mice.
Dubey PK, Patil M, Singh S, Dubey S, Ahuja P, Verma SK, Krishnamurthy P
Molecular and cellular biochemistry 2022 Jan;477(1):129-141
Molecular and cellular biochemistry 2022 Jan;477(1):129-141
PPARα agonist fenofibrate relieves acquired resistance to gefitinib in non-small cell lung cancer by promoting apoptosis via PPARα/AMPK/AKT/FoxO1 pathway.
Wang MS, Han QS, Jia ZR, Chen CS, Qiao C, Liu QQ, Zhang YM, Wang KW, Wang J, Xiao K, Ding XS
Acta pharmacologica Sinica 2022 Jan;43(1):167-176
Acta pharmacologica Sinica 2022 Jan;43(1):167-176
CircRNA_01477 influences axonal growth via regulating miR-3075/FosB/Stat3 axis.
Qian X, Lin G, Wang J, Zhang S, Ma J, Yu B, Wu R, Liu M
Experimental neurology 2022 Jan;347:113905
Experimental neurology 2022 Jan;347:113905
Selective activation of cannabinoid receptor-2 reduces white matter injury via PERK signaling in a rat model of traumatic brain injury.
Li L, Luo Q, Shang B, Yang X, Zhang Y, Pan Q, Wu N, Tang W, Du D, Sun X, Jiang L
Experimental neurology 2022 Jan;347:113899
Experimental neurology 2022 Jan;347:113899
Inhibition of progesterone receptor membrane component-1 exacerbates neonatal hypoxic-ischemic cerebral damage in male mice.
Sun X, Hu Y, Zhou H, Wang S, Zhou C, Lin L, Zhu T, Ge J, Han J, Zhou Y, Jin G, Wang Y, Zu J, Shi H, Yang X, Zan K, Wang J, Hua F
Experimental neurology 2022 Jan;347:113893
Experimental neurology 2022 Jan;347:113893
Novel mutations of TYK2 leading to divergent clinical phenotypes.
Lv G, Sun G, Wu P, Du X, Zeng T, Wen W, Zhou L, An Y, Tang X, He T, Zhao X, Du H
Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology 2022 Jan;33(1):e13671
Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology 2022 Jan;33(1):e13671
Glycocalyx is critical for blood-brain barrier integrity by suppressing caveolin1-dependent endothelial transcytosis following ischemic stroke.
Zhu J, Li Z, Ji Z, Wu Y, He Y, Liu K, Chang Y, Peng Y, Lin Z, Wang S, Wang D, Huang K, Pan S
Brain pathology (Zurich, Switzerland) 2022 Jan;32(1):e13006
Brain pathology (Zurich, Switzerland) 2022 Jan;32(1):e13006
Morphological changes of macrophages and their potential contribution to tendon healing.
Yang QQ, Zhang L, Zhou YL, Tang JB
Colloids and surfaces. B, Biointerfaces 2022 Jan;209(Pt 1):112145
Colloids and surfaces. B, Biointerfaces 2022 Jan;209(Pt 1):112145
Is platelet responsiveness to clopidogrel attenuated in overweight or obese patients and why? A reverse translational study in mice.
Jiang LP, Ji JZ, Ge PX, Zhu T, Mi QY, Tai T, Li YF, Xie HG
British journal of pharmacology 2022 Jan;179(1):46-64
British journal of pharmacology 2022 Jan;179(1):46-64
Silencing TXNIP ameliorates high uric acid-induced insulin resistance via the IRS2/AKT and Nrf2/HO-1 pathways in macrophages.
Yu W, Chen C, Zhuang W, Wang W, Liu W, Zhao H, Lv J, Xie, Wang Q, He F, Xu C, Chen B, Yamamoto T, Koyama H, Cheng J
Free radical biology & medicine 2022 Jan;178:42-53
Free radical biology & medicine 2022 Jan;178:42-53
Ghrelin alleviates 6-hydroxydopamine-induced neurotoxicity in SH-SY5Y cells.
He X, Yuan W, Yang CQ, Zhu L, Liu F, Feng J, Xue YX
Neural regeneration research 2022 Jan;17(1):170-177
Neural regeneration research 2022 Jan;17(1):170-177
3-(3-Hydroxyphenyl)propionic acid, a microbial metabolite of quercetin, inhibits monocyte binding to endothelial cells via modulating E-selectin expression.
Feng J, Ge C, Li W, Li R
Fitoterapia 2022 Jan;156:105071
Fitoterapia 2022 Jan;156:105071
MACF1 promotes osteoblastic cell migration by regulating MAP1B through the GSK3beta/TCF7 pathway.
Su P, Tian Y, Yin C, Wang X, Li D, Yang C, Pei J, Deng X, King S, Li Y, Qian A
Bone 2022 Jan;154:116238
Bone 2022 Jan;154:116238
Synthesis compound XCR-7a ameliorates LPS-induced inflammatory response by inhibiting the phosphorylation of c-Fos.
Tang H, Roy P, Di Q, Ma X, Xiao Y, Wu Z, Quan J, Zhao J, Xiao W, Chen W
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Jan;145:112468
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Jan;145:112468
CAMKK2 Defines Ferroptosis Sensitivity of Melanoma Cells by Regulating AMPK‒NRF2 Pathway.
Wang S, Yi X, Wu Z, Guo S, Dai W, Wang H, Shi Q, Zeng K, Guo W, Li C
The Journal of investigative dermatology 2022 Jan;142(1):189-200.e8
The Journal of investigative dermatology 2022 Jan;142(1):189-200.e8
Luteolin alleviates ischemia/reperfusion injury-induced no-reflow by regulating Wnt/β-catenin signaling in rats.
Qin X, Qin H, Li Z, Xue S, Huang B, Liu X, Wang D
Microvascular research 2022 Jan;139:104266
Microvascular research 2022 Jan;139:104266
Impaired vessel relaxation response and increased infarct size in smooth muscle cannabinoid receptor 1 knockout mice.
Wang LN, Xing MD, Qu WT, Wang CB, Liu ZQ, Han J, Ren W, Qiao YN
Microvascular research 2022 Jan;139:104263
Microvascular research 2022 Jan;139:104263
Minimally modified low-density lipoprotein upregulates mouse mesenteric arterial 5-HT1B receptor in vivo via activation of the JAK2/STAT3 pathway.
Tang HX, Lin J, Xu CB, Chen G, Liao YJ, Lei NR, Li J
Microvascular research 2022 Jan;139:104260
Microvascular research 2022 Jan;139:104260
Overexpression of DOCK6 in oral squamous cell cancer promotes cellular migration and invasion and is associated with poor prognosis.
Zhang ZY, Sun YY, Wang HC, Fu WN, Sun CF
Archives of oral biology 2022 Jan;133:105297
Archives of oral biology 2022 Jan;133:105297
β-Hydroxybutyrate impairs neutrophil migration distance through activation of a protein kinase C and myosin light chain 2 signaling pathway in ketotic cows.
Song Y, Yang Y, Zeng W, Loor JJ, Jiang Q, Peng Z, Li Y, Jiang S, Feng X, Du X, Li X, Liu G
Journal of dairy science 2022 Jan;105(1):761-771
Journal of dairy science 2022 Jan;105(1):761-771
Bioglass promotes wound healing by inhibiting endothelial cell pyroptosis through regulation of the connexin 43/reactive oxygen species (ROS) signaling pathway.
Zhang K, Chai B, Ji H, Chen L, Ma Y, Zhu L, Xu J, Wu Y, Lan Y, Li H, Feng Z, Xiao J, Zhang H, Xu K
Laboratory investigation; a journal of technical methods and pathology 2022 Jan;102(1):90-101
Laboratory investigation; a journal of technical methods and pathology 2022 Jan;102(1):90-101
Cisplatin induces damage of auditory cells: Possible relation with dynamic variation in calcium homeostasis and responding channels.
Zhao H, Xu Y, Song X, Zhang Q, Wang Y, Yin H, Bai X, Li J
European journal of pharmacology 2022 Jan 5;914:174662
European journal of pharmacology 2022 Jan 5;914:174662
Protective role of m6A binding protein YTHDC2 on CCNB2 in manganese-induced spermatogenesis dysfunction.
Qi Z, Liu Y, Yang H, Yang X, Wang H, Liu B, Yuan Y, Wang G, Xu B, Liu W, Xu Z, Deng Y
Chemico-biological interactions 2022 Jan 5;351:109754
Chemico-biological interactions 2022 Jan 5;351:109754
Immunomodulatory Effect of Serum Exosomes From Crohn Disease on Macrophages via Let-7b-5p/TLR4 Signaling.
Gong L, Xiao J, Yi J, Xiao J, Lu F, Liu X
Inflammatory bowel diseases 2022 Jan 5;28(1):96-108
Inflammatory bowel diseases 2022 Jan 5;28(1):96-108
Enteromorpha prolifera polysaccharide-zinc complex modulates the immune response and alleviates LPS-induced intestinal inflammation via inhibiting the TLR4/NF-κB signaling pathway.
Zhang Y, Duan X, Wassie T, Wang HH, Li T, Xie C, Wu X
Food & function 2022 Jan 4;13(1):52-63
Food & function 2022 Jan 4;13(1):52-63
Neuroprotective Effects of Rhodiola Sacra on Transient Global Cerebral Ischemia Through Activating AMPK/Nrf2 Pathway in Rats.
Li K, Jiang J, Shi Z, Zhan L, Peng L, Sun W, Tang Y, Zuo X, Xu E
Antioxidants & redox signaling 2022 Jan 4;
Antioxidants & redox signaling 2022 Jan 4;
Renoprotective activity of Ribes diacanthum pall (RDP) against inflammation in cisplatin-stimulated mice model and human renal tubular epithelial cells.
Wu Y, Zhao L, Gu L, Tilyek A, Yu B, Chai C
Journal of ethnopharmacology 2022 Jan 30;283:114696
Journal of ethnopharmacology 2022 Jan 30;283:114696
Protective effect of oligosaccharides isolated from Panax ginseng C. A. Meyer against UVB-induced skin barrier damage in BALB/c hairless mice and human keratinocytes.
Li Z, Jiang R, Jing C, Liu J, Xu X, Sun L, Zhao D
Journal of ethnopharmacology 2022 Jan 30;283:114677
Journal of ethnopharmacology 2022 Jan 30;283:114677
CHMP2B regulates TDP-43 phosphorylation and cytotoxicity independent of autophagy via CK1.
Deng X, Sun X, Yue W, Duan Y, Hu R, Zhang K, Ni J, Cui J, Wang Q, Chen Y, Li A, Fang Y
The Journal of cell biology 2022 Jan 3;221(1)
The Journal of cell biology 2022 Jan 3;221(1)
LncRNA SNHG16 accelerates atherosclerosis and promotes ox-LDL-induced VSMC growth via the miRNA-22-3p/HMGB2 axis.
Wang Y, Yang Y, Zhang T, Jia S, Ma X, Zhang M, Wang L, Ma A
European journal of pharmacology 2022 Jan 15;915:174601
European journal of pharmacology 2022 Jan 15;915:174601
Salidroside alleviates oxidative stress and apoptosis via AMPK/Nrf2 pathway in DHT-induced human granulosa cell line KGN.
Ji R, Jia FY, Chen X, Wang ZH, Jin WY, Yang J
Archives of biochemistry and biophysics 2022 Jan 15;715:109094
Archives of biochemistry and biophysics 2022 Jan 15;715:109094
Iron overload inhibits cell proliferation and promotes autophagy via PARP1/SIRT1 signaling in endometriosis and adenomyosis.
Zhou Y, Zhao X, Zhang L, Xia Q, Peng Y, Zhang H, Yan D, Yang Z, Li J
Toxicology 2022 Jan 15;465:153050
Toxicology 2022 Jan 15;465:153050
BDE-47 induced PC-12 cell differentiation via TrkA downstream pathways and caused the loss of hippocampal neurons in BALB/c mice.
Liu D, Xue D, Lu W, Yang Z, Li L, Xia B, Wei J, Chen X, Yang Y, Wang X, Lin G
Journal of hazardous materials 2022 Jan 15;422:126850
Journal of hazardous materials 2022 Jan 15;422:126850
Anti-tumor effect of Yanggan Huayu granule by inducing AKT-mediated apoptosis in hepatocellular carcinoma.
Shen Y, Yang F, Peng H, Zhang G, Zhu F, Xu H, Shi L
Journal of ethnopharmacology 2022 Jan 10;282:114601
Journal of ethnopharmacology 2022 Jan 10;282:114601
Ajuba functions as a co-activator of C/EBPβ to induce expression of PPARγ and C/EBPα during adipogenesis.
Yan H, Li Q, Li M, Zou X, Bai N, Yu Z, Zhang J, Zhang D, Zhang Q, Wang J, Jia H, Wu Y, Hou Z
Molecular and cellular endocrinology 2022 Jan 1;539:111485
Molecular and cellular endocrinology 2022 Jan 1;539:111485
Highly sensitive detection of multiple proteins from single cells by MoS2-FET biosensors.
Wei J, Zhao Z, Lan K, Wang Z, Qin G, Chen R
Talanta 2022 Jan 1;236:122839
Talanta 2022 Jan 1;236:122839
Delayed inhibition of ERK and p38 attenuates neuropathic pain without affecting motor function recovery after peripheral nerve injury.
Huang S, Chen Y, Jia Y, Yang T, Su W, Zhu Z, Xue P, Feng F, Zhao Y, Chen G
Neuropharmacology 2022 Jan 1;202:108835
Neuropharmacology 2022 Jan 1;202:108835
NMN recruits GSH to enhance GPX4-mediated ferroptosis defense in UV irradiation induced skin injury.
Feng Z, Qin Y, Huo F, Jian Z, Li X, Geng J, Li Y, Wu J
Biochimica et biophysica acta. Molecular basis of disease 2022 Jan 1;1868(1):166287
Biochimica et biophysica acta. Molecular basis of disease 2022 Jan 1;1868(1):166287
Docosahexaenoic acid reduces hypoglycemia-induced neuronal necroptosis via the peroxisome proliferator-activated receptor γ/nuclear factor-κB pathway.
Huang L, Zhou Y, Gou ZX, Zhang F, Lu LQ
Brain research 2022 Jan 1;1774:147708
Brain research 2022 Jan 1;1774:147708
The Impact of Long-term Physical Inactivity on Adipose Tissue Immunometabolism.
Trim WV, Walhin JP, Koumanov F, Bouloumié A, Lindsay MA, Travers RL, Turner JE, Thompson D
The Journal of clinical endocrinology and metabolism 2022 Jan 1;107(1):177-191
The Journal of clinical endocrinology and metabolism 2022 Jan 1;107(1):177-191
Dapagliflozin alleviates advanced glycation end product induced podocyte injury through AMPK/mTOR mediated autophagy pathway.
Yang L, Liang B, Li J, Zhang X, Chen H, Sun J, Zhang Z
Cellular signalling 2022 Feb;90:110206
Cellular signalling 2022 Feb;90:110206
DHHC5 facilitates oligodendrocyte development by palmitoylating and activating STAT3.
Ma Y, Liu H, Ou Z, Qi C, Xing R, Wang S, Han Y, Zhao TJ, Chen Y
Glia 2022 Feb;70(2):379-392
Glia 2022 Feb;70(2):379-392
Inhibition of gap junction communication between cells can induce apoptosis of corpus cavernosum smooth muscle in guinea pigs.
Wang Y, Wang J, Hao Z, Yang H, Li Y, Tan M, Liu L, Feng S, Mei L, Qian B
Andrologia 2022 Feb;54(1):e14287
Andrologia 2022 Feb;54(1):e14287
Tanshinone IIA inhibits gastric cancer cell stemness through inducing ferroptosis.
Ni H, Ruan G, Sun C, Yang X, Miao Z, Li J, Chen Y, Qin H, Liu Y, Zheng L, Xing Y, Xi T, Li X
Environmental toxicology 2022 Feb;37(2):192-200
Environmental toxicology 2022 Feb;37(2):192-200
Neuroglobin expression and function in the temporal cortex of bilirubin encephalopathy rats.
Hu JH, Fan P, Zhang LR, Chen CY, Xu J, Huang J, Lu WT, Zhu SJ, Qiu GP, Xu SY, Ran JH, Gan SW
Anatomical record (Hoboken, N.J. : 2007) 2022 Feb;305(2):254-264
Anatomical record (Hoboken, N.J. : 2007) 2022 Feb;305(2):254-264
Combination of the 6-thioguanine and disulfiram/Cu synergistically inhibits proliferation of triple-negative breast cancer cells by enhancing DNA damage and disrupting DNA damage checkpoint.
Chu M, An X, Zhang D, Li Q, Dai X, Yu H, Li Z
Biochimica et biophysica acta. Molecular cell research 2022 Feb;1869(2):119169
Biochimica et biophysica acta. Molecular cell research 2022 Feb;1869(2):119169
Dietary mulberry-leaf flavonoids improve the eggshell quality of aged breeder hens.
Huang Z, Dai H, Jiang J, Ye N, Zhu S, Wei Q, Lv Z, Shi F
Theriogenology 2022 Feb;179:177-186
Theriogenology 2022 Feb;179:177-186
Pre-clinical study of human umbilical cord mesenchymal stem cell transplantation for the treatment of traumatic brain injury: safety evaluation from immunogenic and oncogenic perspectives.
Wang G, Wu HL, Liu YP, Yan DQ, Yuan ZL, Chen L, Yang Q, Gao YS, Diao B
Neural regeneration research 2022 Feb;17(2):354-361
Neural regeneration research 2022 Feb;17(2):354-361
LncRNA MT1DP promotes cadmium-induced DNA replication stress by inhibiting chromatin recruitment of SMARCAL1.
Feng W, Qi Z, Dong Z, Liu W, Xu M, Gao M, Liu S
The Science of the total environment 2022 Feb 10;807(Pt 3):151078
The Science of the total environment 2022 Feb 10;807(Pt 3):151078
OGDHL ameliorates cognitive impairment and Alzheimer's disease-like pathology via activating Wnt/β-catenin signaling in Alzheimer's disease mice.
Yao L, Xu X, Xu Y, Li C, Xie F, Guo M, Liu Z, Liu X
Behavioural brain research 2022 Feb 10;418:113673
Behavioural brain research 2022 Feb 10;418:113673
Anti-fatigue effect of hypericin in a chronic forced exercise mouse model.
Sun Y, Liang C, Zheng L, Liu L, Li Z, Yang G, Li Y
Journal of ethnopharmacology 2022 Feb 10;284:114767
Journal of ethnopharmacology 2022 Feb 10;284:114767
A novel role for apatinib in enhancing radiosensitivity in non-small cell lung cancer cells by suppressing the AKT and ERK pathways.
Li L, Li Y, Zou H
PeerJ 2021;9:e12356
PeerJ 2021;9:e12356
Identification and validation of candidate genes dysregulated in alveolar macrophages of acute respiratory distress syndrome.
Mao Y, Lv X, Xu W, Ying Y, Qin Z, Liao H, Chen L, Liu Y
PeerJ 2021;9:e12312
PeerJ 2021;9:e12312
N-acetyl-L-tryptophan attenuates hepatic ischemia-reperfusion injury via regulating TLR4/NLRP3 signaling pathway in rats.
Pan Y, Yu S, Wang J, Li W, Li H, Bai C, Sheng Y, Li M, Wang C, Liu J, Xie P, Wang C, Jiang J, Li J
PeerJ 2021;9:e11909
PeerJ 2021;9:e11909
Involvement of plasminogen activator inhibitor-1 and its related molecules in atrial fibrosis in patients with atrial fibrillation.
Li Q, Lai Y, Gao X, Li X, Deng CY, Guo H, Zhao J, Yang H, Xu Y, Wu S, Xue Y, Rao F
PeerJ 2021;9:e11488
PeerJ 2021;9:e11488
Identification of potential genes in upper tract urothelial carcinoma using next-generation sequencing with bioinformatics and in vitro analyses.
Lee HY, Li CC, Li WM, Hsu YL, Yeh HC, Ke HL, Yeh BW, Huang CN, Li CF, Kuo PL, Wu WJ
PeerJ 2021;9:e11343
PeerJ 2021;9:e11343
Melatonin ameliorates myocardial injury by reducing apoptosis and autophagy of cardiomyocytes in a rat cardiopulmonary bypass model.
Huang X, Hou J, Huang S, Feng K, Yue Y, Li H, Huang S, Liang M, Chen G, Wu Z
PeerJ 2021;9:e11264
PeerJ 2021;9:e11264
Long non-coding RNA taurine upregulated gene 1 is downregulated in osteoporosis and influences the osteogenic differentiation of bone marrow mesenchymal stem cells.
Teng Z, Zhu Y, Hao Q, Yu X, Teng Y, Yue Q, Zhang X, Lu S
PeerJ 2021;9:e11251
PeerJ 2021;9:e11251
Screening and identification of endometrial proteins as novel potential biomarkers for repeated implantation failure.
Wang C, Feng Y, Zhou WJ, Cheng ZJ, Jiang MY, Zhou Y, Fei XY
PeerJ 2021;9:e11009
PeerJ 2021;9:e11009
Curdione and Schisandrin C Synergistically Reverse Hepatic Fibrosis via Modulating the TGF-β Pathway and Inhibiting Oxidative Stress.
Dai W, Qin Q, Li Z, Lin L, Li R, Fang Z, Han Y, Mu W, Ren L, Liu T, Zhan X, Xiao X, Bai Z
Frontiers in cell and developmental biology 2021;9:763864
Frontiers in cell and developmental biology 2021;9:763864
Platelet-Derived Microvesicles Promote VSMC Dedifferentiation After Intimal Injury via Src/Lamtor1/mTORC1 Signaling.
Liu JT, Bao H, Fan YJ, Li ZT, Yao QP, Han Y, Zhang ML, Jiang ZL, Qi YX
Frontiers in cell and developmental biology 2021;9:744320
Frontiers in cell and developmental biology 2021;9:744320
An Advanced Systems Pharmacology Strategy Reveals AKR1B1, MMP2, PTGER3 as Key Genes in the Competing Endogenous RNA Network of Compound Kushen Injection Treating Gastric Carcinoma by Integrated Bioinformatics and Experimental Verification.
Zhou W, Wu C, Zhao C, Huang Z, Lu S, Fan X, Tan Y, Stalin A, You R, Liu X, Zhang J, Wu Z, Wu J
Frontiers in cell and developmental biology 2021;9:742421
Frontiers in cell and developmental biology 2021;9:742421
Reducing Inflammation and Vascular Invasion in Intervertebral Disc Degeneration via Cystathionine-γ-Lyase Inhibitory Effect on E-Selectin.
Xu H, Wei K, Tu J, Chen Y, He Y, Ding Y, Xu H, Bao X, Xie H, Fang H, Wang H
Frontiers in cell and developmental biology 2021;9:741046
Frontiers in cell and developmental biology 2021;9:741046
PBX1 Attenuates Hair Follicle-Derived Mesenchymal Stem Cell Senescence and Apoptosis by Alleviating Reactive Oxygen Species-Mediated DNA Damage Instead of Enhancing DNA Damage Repair.
Wang Y, Sui Y, Lian A, Han X, Liu F, Zuo K, Liu M, Sun W, Wang Z, Liu Z, Zou F, Lu R, Jin M, Du H, Xu K, Liu X, Liu J
Frontiers in cell and developmental biology 2021;9:739868
Frontiers in cell and developmental biology 2021;9:739868
Increased Nuclear Transporter Importin 7 Contributes to the Tumor Growth and Correlates With CD8 T Cell Infiltration in Cervical Cancer.
Chen J, Hu Y, Teng Y, Yang B
Frontiers in cell and developmental biology 2021;9:732786
Frontiers in cell and developmental biology 2021;9:732786
LncRNA RNA Component of Mitochondrial RNA-Processing Endoribonuclease Promotes AKT-Dependent Breast Cancer Growth and Migration by Trapping MicroRNA-206.
Huang Y, Xie B, Cao M, Lu H, Wu X, Hao Q, Zhou X
Frontiers in cell and developmental biology 2021;9:730538
Frontiers in cell and developmental biology 2021;9:730538
PRDM16 Inhibits Cell Proliferation and Migration via Epithelial-to-Mesenchymal Transition by Directly Targeting Pyruvate Carboxylase in Papillary Thyroid Cancer.
Liu WL, Guan Q, Wen D, Ma B, Xu WB, Hu JQ, Wei WJ, Li DS, Wang Y, Xiang J, Liao T, Ji QH
Frontiers in cell and developmental biology 2021;9:723777
Frontiers in cell and developmental biology 2021;9:723777
Macrophage-Mediated Bone Formation in Scaffolds Modified With MSC-Derived Extracellular Matrix Is Dependent on the Migration Inhibitory Factor Signaling Pathway.
Deng M, Tan J, Dai Q, Luo F, Xu J
Frontiers in cell and developmental biology 2021;9:714011
Frontiers in cell and developmental biology 2021;9:714011
Depletion of Demethylase KDM6 Enhances Early Neuroectoderm Commitment of Human PSCs.
Meng Y, Zhang T, Zheng R, Ding S, Yang J, Liu R, Jiang Y, Jiang W
Frontiers in cell and developmental biology 2021;9:702462
Frontiers in cell and developmental biology 2021;9:702462
Design, Synthesis, and Biological Evaluation of Pyrano[2,3-c]-pyrazole-Based RalA Inhibitors Against Hepatocellular Carcinoma.
Wang Y, He M, Li X, Chai J, Jiang Q, Peng C, He G, Huang W
Frontiers in chemistry 2021;9:700956
Frontiers in chemistry 2021;9:700956
Cardiac Overexpression of XIN Prevents Dilated Cardiomyopathy Caused by TNNT2 ΔK210 Mutation.
Li B, Guo Y, Zhan Y, Zhou X, Li Y, Zhao C, Sun N, Xu C, Liang Q
Frontiers in cell and developmental biology 2021;9:691749
Frontiers in cell and developmental biology 2021;9:691749
LncRNA CRNDE Promotes ATG4B-Mediated Autophagy and Alleviates the Sensitivity of Sorafenib in Hepatocellular Carcinoma Cells.
Chen L, Sun L, Dai X, Li T, Yan X, Zhang Y, Xiao H, Shen X, Huang G, Xiang W, Zhang Y, Tan D, Yang S, Nie Y, Huang X, Lian J, He F
Frontiers in cell and developmental biology 2021;9:687524
Frontiers in cell and developmental biology 2021;9:687524
GDF11 Alleviates Pathological Myocardial Remodeling in Diabetic Cardiomyopathy Through SIRT1-Dependent Regulation of Oxidative Stress and Apoptosis.
Zhu HZ, Zhang LY, Zhai ME, Xia L, Cao Y, Xu L, Li KF, Jiang LQ, Shi H, Li X, Zhou YN, Ding W, Wang DX, Gao EH, Liu JC, Yu SQ, Duan WX
Frontiers in cell and developmental biology 2021;9:686848
Frontiers in cell and developmental biology 2021;9:686848
SUN5 Interacting With Nesprin3 Plays an Essential Role in Sperm Head-to-Tail Linkage: Research on Sun5 Gene Knockout Mice.
Zhang Y, Yang L, Huang L, Liu G, Nie X, Zhang X, Xing X
Frontiers in cell and developmental biology 2021;9:684826
Frontiers in cell and developmental biology 2021;9:684826
Autophagy-Related LC3 Accumulation Interacted Directly With LIR Containing RIPK1 and RIPK3, Stimulating Necroptosis in Hypoxic Cardiomyocytes.
Huang Y, Feng Y, Cui L, Yang L, Zhang Q, Zhang J, Jiang X, Zhang X, Lv Y, Jia JZ, Zhang DX, Huang YS
Frontiers in cell and developmental biology 2021;9:679637
Frontiers in cell and developmental biology 2021;9:679637
Quiescin Sulfhydryl Oxidase 2 Overexpression Predicts Poor Prognosis and Tumor Progression in Patients With Colorectal Cancer: A Study Based on Data Mining and Clinical Verification.
Jiang T, Zheng L, Li X, Liu J, Song H, Xu Y, Dong C, Liu L, Wang H, Wang S, Wang R, Song J
Frontiers in cell and developmental biology 2021;9:678770
Frontiers in cell and developmental biology 2021;9:678770
NudC L279P Mutation Destabilizes Filamin A by Inhibiting the Hsp90 Chaperoning Pathway and Suppresses Cell Migration.
Liu M, Xu Z, Zhang C, Yang C, Feng J, Lu Y, Zhang W, Chen W, Xu X, Sun X, Yang M, Liu W, Zhou T, Yang Y
Frontiers in cell and developmental biology 2021;9:671233
Frontiers in cell and developmental biology 2021;9:671233
Exosomal miR-2276-5p in Plasma Is a Potential Diagnostic and Prognostic Biomarker in Glioma.
Sun J, Sun Z, Gareev I, Yan T, Chen X, Ahmad A, Zhang D, Zhao B, Beylerli O, Yang G, Zhao S
Frontiers in cell and developmental biology 2021;9:671202
Frontiers in cell and developmental biology 2021;9:671202
Comprehensive Analysis of the Transcriptome-Wide m6A Methylome in Pterygium by MeRIP Sequencing.
Jiang Y, Zhang X, Zhang X, Zhao K, Zhang J, Yang C, Chen Y
Frontiers in cell and developmental biology 2021;9:670528
Frontiers in cell and developmental biology 2021;9:670528
α-Enolase Lies Downstream of mTOR/HIF1α and Promotes Thyroid Carcinoma Progression by Regulating CST1.
Liu Y, Liao L, An C, Wang X, Li Z, Xu Z, Liu J, Liu S
Frontiers in cell and developmental biology 2021;9:670019
Frontiers in cell and developmental biology 2021;9:670019
Force-Induced Autophagy in Periodontal Ligament Stem Cells Modulates M1 Macrophage Polarization via AKT Signaling.
Jiang N, He D, Ma Y, Su J, Wu X, Cui S, Li Z, Zhou Y, Yu H, Liu Y
Frontiers in cell and developmental biology 2021;9:666631
Frontiers in cell and developmental biology 2021;9:666631
SP1-Mediated Upregulation of Long Noncoding RNA ZFAS1 Involved in Non-syndromic Cleft Lip and Palate via Inactivating WNT/β-Catenin Signaling Pathway.
Chen S, Jia Z, Cai M, Ye M, Wu D, Wan T, Zhang B, Wu P, Xu Y, Guo Y, Tian C, Ma D, Ma J
Frontiers in cell and developmental biology 2021;9:662780
Frontiers in cell and developmental biology 2021;9:662780
NLGN3 Upregulates Expression of ADAM10 to Promote the Cleavage of NLGN3 via Activating the LYN Pathway in Human Gliomas.
Dang NN, Li XB, Zhang M, Han C, Fan XY, Huang SH
Frontiers in cell and developmental biology 2021;9:662763
Frontiers in cell and developmental biology 2021;9:662763
The E3 Ligase PIAS1 Regulates p53 Sumoylation to Control Stress-Induced Apoptosis of Lens Epithelial Cells Through the Proapoptotic Regulator Bax.
Nie Q, Chen H, Zou M, Wang L, Hou M, Xiang JW, Luo Z, Gong XD, Fu JL, Wang Y, Zheng SY, Xiao Y, Gan YW, Gao Q, Bai YY, Wang JM, Zhang L, Tang XC, Hu X, Gong L, Liu Y, Li DW
Frontiers in cell and developmental biology 2021;9:660494
Frontiers in cell and developmental biology 2021;9:660494
Platelet-Rich Plasma Induces Autophagy and Promotes Regeneration in Human Dental Pulp Cells.
Xu H, Xu F, Zhao J, Zhou C, Liu J
Frontiers in bioengineering and biotechnology 2021;9:659742
Frontiers in bioengineering and biotechnology 2021;9:659742
BRD7 Promotes Cell Proliferation and Tumor Growth Through Stabilization of c-Myc in Colorectal Cancer.
Zhao R, Liu Y, Wu C, Li M, Wei Y, Niu W, Yang J, Fan S, Xie Y, Li H, Wang W, Zeng Z, Xiong W, Li X, Li G, Zhou M
Frontiers in cell and developmental biology 2021;9:659392
Frontiers in cell and developmental biology 2021;9:659392
BMSC-Derived Small Extracellular Vesicles Induce Cartilage Reconstruction of Temporomandibular Joint Osteoarthritis via Autotaxin-YAP Signaling Axis.
Wang Y, Zhao M, Li W, Yang Y, Zhang Z, Ma R, Wu M
Frontiers in cell and developmental biology 2021;9:656153
Frontiers in cell and developmental biology 2021;9:656153
LINC00511/miRNA-143-3p Modulates Apoptosis and Malignant Phenotype of Bladder Carcinoma Cells via PCMT1.
Dong LM, Zhang XL, Mao MH, Li YP, Zhang XY, Xue DW, Liu YL
Frontiers in cell and developmental biology 2021;9:650999
Frontiers in cell and developmental biology 2021;9:650999
Urea as a By-Product of Ammonia Metabolism Can Be a Potential Serum Biomarker of Hepatocellular Carcinoma.
Bai C, Wang H, Dong D, Li T, Yu Z, Guo J, Zhou W, Li D, Yan R, Wang L, Wang Z, Li Y, Ren L
Frontiers in cell and developmental biology 2021;9:650748
Frontiers in cell and developmental biology 2021;9:650748
Inhibition of JAK-STAT Signaling Pathway Alleviates Age-Related Phenotypes in Tendon Stem/Progenitor Cells.
Chen M, Xiao L, Dai G, Lu P, Zhang Y, Li Y, Ni M, Rui Y
Frontiers in cell and developmental biology 2021;9:650250
Frontiers in cell and developmental biology 2021;9:650250
β-Arrestin1 Promotes Colorectal Cancer Metastasis Through GSK-3β/β-Catenin Signaling- Mediated Epithelial-to-Mesenchymal Transition.
Song Q, Han Z, Wu X, Wang Y, Zhou L, Yang L, Liu N, Sui H, Cai J, Ji Q, Li Q
Frontiers in cell and developmental biology 2021;9:650067
Frontiers in cell and developmental biology 2021;9:650067
Cartilage Endplate Stem Cells Transdifferentiate Into Nucleus Pulposus Cells via Autocrine Exosomes.
Luo L, Gong J, Zhang H, Qin J, Li C, Zhang J, Tang Y, Zhang Y, Chen J, Zhou Y, Tian Z, Liu Y, Liu M
Frontiers in cell and developmental biology 2021;9:648201
Frontiers in cell and developmental biology 2021;9:648201
CORO6 Promotes Cell Growth and Invasion of Clear Cell Renal Cell Carcinoma via Activation of WNT Signaling.
Wang X, Xiao Y, Li S, Yan Z, Luo G
Frontiers in cell and developmental biology 2021;9:647301
Frontiers in cell and developmental biology 2021;9:647301
TAp63α Is Involved in Tobacco Smoke-Induced Lung Cancer EMT and the Anti-cancer Activity of Curcumin via miR-19 Transcriptional Suppression.
Xie C, Zhu J, Yang X, Huang C, Zhou L, Meng Z, Li X, Zhong C
Frontiers in cell and developmental biology 2021;9:645402
Frontiers in cell and developmental biology 2021;9:645402
Hypoxia-Induced LIN28A mRNA Promotes the Metastasis of Colon Cancer in a Protein-Coding-Independent Manner.
Weng M, Feng Y, He Y, Yang W, Li J, Zhu Y, Wang T, Wang C, Zhang X, Qiao Y, Li Q, Zhao L, Gao S, Zhang L, Wu Y, Zhao R, Wang G, Li Z, Jin X, Zheng T, Li X
Frontiers in cell and developmental biology 2021;9:642930
Frontiers in cell and developmental biology 2021;9:642930
A Novel CpG Methylation Risk Indicator for Predicting Prognosis in Bladder Cancer.
Guo Y, Yin J, Dai Y, Guan Y, Chen P, Chen Y, Huang C, Lu YJ, Zhang L, Song D
Frontiers in cell and developmental biology 2021;9:642650
Frontiers in cell and developmental biology 2021;9:642650
Exosomal miR-3682-3p Suppresses Angiogenesis by Targeting ANGPT1 via the RAS-MEK1/2-ERK1/2 Pathway in Hepatocellular Carcinoma.
Dong SS, Dong DD, Yang ZF, Zhu GQ, Gao DM, Chen J, Zhao Y, Liu BB
Frontiers in cell and developmental biology 2021;9:633358
Frontiers in cell and developmental biology 2021;9:633358
Establishment of an Efficient Primary Culture System for Human Hair Follicle Stem Cells Using the Rho-Associated Protein Kinase Inhibitor Y-27632.
Wen L, Miao Y, Fan Z, Zhang J, Guo Y, Dai D, Huang J, Liu Z, Chen R, Hu Z
Frontiers in cell and developmental biology 2021;9:632882
Frontiers in cell and developmental biology 2021;9:632882
Grb2 Induces Cardiorenal Syndrome Type 3: Roles of IL-6, Cardiomyocyte Bioenergetics, and Akt/mTOR Pathway.
Wang J, Sun X, Wang X, Cui S, Liu R, Liu J, Fu B, Gong M, Wang C, Shi Y, Chen Q, Cai G, Chen X
Frontiers in cell and developmental biology 2021;9:630412
Frontiers in cell and developmental biology 2021;9:630412
Extracellular Vesicles Carry lncRNA SNHG16 to Promote Metastasis of Breast Cancer Cells via the miR-892b/PPAPDC1A Axis.
Xia W, Liu Y, Cheng T, Xu T, Dong M, Hu X
Frontiers in cell and developmental biology 2021;9:628573
Frontiers in cell and developmental biology 2021;9:628573
The Protective Effect of 1,25(OH)2D3 on Myocardial Function is Mediated via Sirtuin 3-Regulated Fatty Acid Metabolism.
Yang J, Zhang Y, Pan Y, Sun C, Liu Z, Liu N, Fu Y, Li X, Li Y, Kong J
Frontiers in cell and developmental biology 2021;9:627135
Frontiers in cell and developmental biology 2021;9:627135
LUZP1 Controls Cell Division, Migration and Invasion Through Regulation of the Actin Cytoskeleton.
Bozal-Basterra L, Gonzalez-Santamarta M, Muratore V, Martín-Martín N, Ercilla A, Rodríguez JA, Carracedo A, Sutherland JD, Barrio R
Frontiers in cell and developmental biology 2021;9:624089
Frontiers in cell and developmental biology 2021;9:624089
High-Fat Diet Induced Gut Microbiota Alterations Associating With Ghrelin/Jak2/Stat3 Up-Regulation to Promote Benign Prostatic Hyperplasia Development.
Gu M, Liu C, Yang T, Zhan M, Cai Z, Chen Y, Chen Q, Wang Z
Frontiers in cell and developmental biology 2021;9:615928
Frontiers in cell and developmental biology 2021;9:615928
Hypoglycemic Efficacy of Rh-aFGF Variants in Treatment of Diabetes in ZDF Rats.
Zhang L, Zhou Q, Chen M, Yang X, Lu C, Sun W, Hui Q, Wang X
Frontiers in cell and developmental biology 2021;9:609383
Frontiers in cell and developmental biology 2021;9:609383
Deficiency of Sirtuin 1 Impedes Endometrial Decidualization in Recurrent Implantation Failure Patients.
Li J, Qi J, Yao G, Zhu Q, Li X, Xu R, Zhu Z, Zhao H, Wang Y, Ding Y, Sun Y
Frontiers in cell and developmental biology 2021;9:598364
Frontiers in cell and developmental biology 2021;9:598364
Retinoic Acid Signaling Plays a Crucial Role in Excessive Caffeine Intake-Disturbed Apoptosis and Differentiation of Myogenic Progenitors.
Wu N, Li Y, He X, Lin J, Long D, Cheng X, Brand-Saberi B, Wang G, Yang X
Frontiers in cell and developmental biology 2021;9:586767
Frontiers in cell and developmental biology 2021;9:586767
MNSFβ Promotes the Proliferation and Migration of Human Extravillous Trophoblast Cells and the Villus Expression Level of MNSFβ Is Decreased in Recurrent Miscarriage Patients.
Wang N, Yang Q, Gu Y, Zhen X, Shi Y, Gu W, Wang J, He Y, Wang J
Gynecologic and obstetric investigation 2021;86(1-2):27-39
Gynecologic and obstetric investigation 2021;86(1-2):27-39
Microenvironment Stiffness Amplifies Post-ischemia Heart Regeneration in Response to Exogenous Extracellular Matrix Proteins in Neonatal Mice.
Wang X, Pierre V, Senapati S, Park PS, Senyo SE
Frontiers in cardiovascular medicine 2021;8:773978
Frontiers in cardiovascular medicine 2021;8:773978
Maslinic Acid Attenuates Ischemia/Reperfusion Injury-Induced Myocardial Inflammation and Apoptosis by Regulating HMGB1-TLR4 Axis.
Li Q, Xu M, Li Z, Li T, Wang Y, Chen Q, Wang Y, Feng J, Yin X, Lu C
Frontiers in cardiovascular medicine 2021;8:768947
Frontiers in cardiovascular medicine 2021;8:768947
Vanadium Induces Oxidative Stress and Mitochondrial Quality Control Disorder in the Heart of Ducks.
Xiong Z, Xing C, Xu T, Yang Y, Liu G, Hu G, Cao H, Zhang C, Guo X, Yang F
Frontiers in veterinary science 2021;8:756534
Frontiers in veterinary science 2021;8:756534
Methylation and Expression of the Exercise-Related TLR1 Gene Is Associated With Low Grade Glioma Prognosis and Outcome.
Lu L, Hu Y, Wang C, Jiang F, Wu C
Frontiers in molecular biosciences 2021;8:747933
Frontiers in molecular biosciences 2021;8:747933
Comprehensive Analysis of REST/NRSF Gene in Glioma and Its ceRNA Network Identification.
Zhang Y, Wang Q, Wang Z, Zhang C, Xu X, Xu J, Ren H, Shao X, Zhen X, Zhang L, Yu Y
Frontiers in medicine 2021;8:739624
Frontiers in medicine 2021;8:739624
S-Propargyl-Cysteine Attenuates Diabetic Cardiomyopathy in db/db Mice Through Activation of Cardiac Insulin Receptor Signaling.
Li Y, Xie KF, Chang YH, Wang C, Chen Y, Wang MJ, Zhu YC
Frontiers in cardiovascular medicine 2021;8:737191
Frontiers in cardiovascular medicine 2021;8:737191
PIEZO1 Ion Channel Mediates Ionizing Radiation-Induced Pulmonary Endothelial Cell Ferroptosis via Ca2+/Calpain/VE-Cadherin Signaling.
Guo XW, Zhang H, Huang JQ, Wang SN, Lu Y, Cheng B, Dong SH, Wang YY, Li FS, Li YW
Frontiers in molecular biosciences 2021;8:725274
Frontiers in molecular biosciences 2021;8:725274
Developmental Angiogenesis Requires the Mitochondrial Phenylalanyl-tRNA Synthetase.
Li B, Chen K, Liu F, Zhang J, Chen X, Chen T, Chen Q, Yao Y, Hu W, Wang L, Wu Y
Frontiers in cardiovascular medicine 2021;8:724846
Frontiers in cardiovascular medicine 2021;8:724846
MiR-3064 in Epicardial Adipose-Derived Exosomes Targets Neuronatin to Regulate Adipogenic Differentiation of Epicardial Adipose Stem Cells.
Yang W, Tu H, Tang K, Huang H, Ou S, Wu J
Frontiers in cardiovascular medicine 2021;8:709079
Frontiers in cardiovascular medicine 2021;8:709079
CUX1 Facilitates the Development of Oncogenic Properties Via Activating Wnt/β-Catenin Signaling Pathway in Glioma.
Feng F, Zhao Z, Zhou Y, Cheng Y, Wu X, Heng X
Frontiers in molecular biosciences 2021;8:705008
Frontiers in molecular biosciences 2021;8:705008
Expression and Functional Analysis of lncRNAs Involved in Platelet-Derived Growth Factor-BB-Induced Proliferation of Human Aortic Smooth Muscle Cells.
Lin JJ, Chen W, Gong M, Xu X, Du MY, Wang SF, Yang LY, Wang Y, Liu KX, Kong P, Li B, Liu K, Li YM, Dong LH, Sun SG
Frontiers in cardiovascular medicine 2021;8:702718
Frontiers in cardiovascular medicine 2021;8:702718
Traditional Chinese Medication Qiliqiangxin Attenuates Diabetic Cardiomyopathy via Activating PPARγ.
Wu X, Zhang T, Lyu P, Chen M, Ni G, Cheng H, Xu G, Li X, Wang L, Shang H
Frontiers in cardiovascular medicine 2021;8:698056
Frontiers in cardiovascular medicine 2021;8:698056
ZEB1 Mediates Bone Marrow Mesenchymal Stem Cell Osteogenic Differentiation Partly via Wnt/β-Catenin Signaling.
Xu C, Shi H, Jiang X, Fan Y, Huang D, Qi X, Cheng Q
Frontiers in molecular biosciences 2021;8:682728
Frontiers in molecular biosciences 2021;8:682728
Whole-Transcriptome Analysis of LncRNAs Mediated ceRNA Regulation in Granulosa Cells Isolated From Healthy and Atresia Follicles of Chinese Buffalo.
Pan Y, Yang S, Cheng J, Lv Q, Xing Q, Zhang R, Liang J, Shi D, Deng Y
Frontiers in veterinary science 2021;8:680182
Frontiers in veterinary science 2021;8:680182
CRISPR/dCas9-Mediated Parkin Inhibition Impairs Mitophagy and Aggravates Apoptosis of Rat Nucleus Pulposus Cells Under Oxidative Stress.
Lan T, Zheng YC, Li ND, Chen XS, Shen Z, Yan B
Frontiers in molecular biosciences 2021;8:674632
Frontiers in molecular biosciences 2021;8:674632
Pharmacological Activating Transcription Factor 6 Activation Is Beneficial for Liver Retrieval With ex vivo Normothermic Mechanical Perfusion From Cardiac Dead Donor Rats.
Cheng N, Shi JH, Jin Y, Shi YB, Liu XD, Zhang HP, Cao SL, Yang H, Guo WZ, Zhang SJ
Frontiers in surgery 2021;8:665260
Frontiers in surgery 2021;8:665260
Identification of Proteomic Signatures in Chronic Obstructive Pulmonary Disease Emphysematous Phenotype.
Bai S, Ye R, Wang C, Sun P, Wang D, Yue Y, Wang H, Wu S, Yu M, Xi S, Zhao L
Frontiers in molecular biosciences 2021;8:650604
Frontiers in molecular biosciences 2021;8:650604
WDR45 Mutation Impairs the Autophagic Degradation of Transferrin Receptor and Promotes Ferroptosis.
Xiong Q, Li X, Li W, Chen G, Xiao H, Li P, Wu C
Frontiers in molecular biosciences 2021;8:645831
Frontiers in molecular biosciences 2021;8:645831
Antiretroviral Drugs Regulate Epigenetic Modification of Cardiac Cells Through Modulation of H3K9 and H3K27 Acetylation.
Kashyap S, Mukker A, Gupta D, Datta PK, Rappaport J, Jacobson JM, Ebert SN, Gupta MK
Frontiers in cardiovascular medicine 2021;8:634774
Frontiers in cardiovascular medicine 2021;8:634774
Acitretin Promotes the Differentiation of Myeloid-Derived Suppressor Cells in the Treatment of Psoriasis.
Liu P, Peng C, Chen X, Wu L, Yin M, Li J, Qin Q, Kuang Y, Zhu W
Frontiers in medicine 2021;8:625130
Frontiers in medicine 2021;8:625130
Tanshinone IIA Combined With Cyclosporine A Alleviates Lung Apoptosis Induced by Renal Ischemia-Reperfusion in Obese Rats.
Tai H, Jiang XL, Song N, Xiao HH, Li Y, Cheng MJ, Yin XM, Chen YR, Yang GL, Jiang XY, Kuang JS, Lan ZM, Jia LQ
Frontiers in medicine 2021;8:617393
Frontiers in medicine 2021;8:617393
CYP2C8 Suppress Proliferation, Migration, Invasion and Sorafenib Resistance of Hepatocellular Carcinoma via PI3K/Akt/p27kip1 Axis.
Zhou X, Li TM, Luo JZ, Lan CL, Wei ZL, Fu TH, Liao XW, Zhu GZ, Ye XP, Peng T
Journal of hepatocellular carcinoma 2021;8:1323-1338
Journal of hepatocellular carcinoma 2021;8:1323-1338
Cannabisin D from Sinomenium Acutum Inhibits Proliferation and Migration of Glioblastoma Cells through MAPKs Signaling.
Zhang D, Li C, Zhang L, Li B, Wang Y, Wang R, Chen Z, Xu L, Liu T
Nutrition and cancer 2021;73(11-12):2491-2501
Nutrition and cancer 2021;73(11-12):2491-2501
The mechanism and candidate compounds of aged citrus peel (chenpi) preventing chronic obstructive pulmonary disease and its progression to lung cancer.
Zhou L, Gu W, Kui F, Gao F, Niu Y, Li W, Zhang Y, Guo L, Wang J, Guo Z, Du G
Food & nutrition research 2021;65
Food & nutrition research 2021;65
Disulfiram Chelated with Copper Promotes Apoptosis in Osteosarcoma via ROS/Mitochondria Pathway.
Ren Y, Lin Y, Chen J, Jin Y
Biological & pharmaceutical bulletin 2021;44(10):1557-1564
Biological & pharmaceutical bulletin 2021;44(10):1557-1564
Discovery and Verification of Key Liver Cancer Genes and Alternative Splicing Events Based on Second-Generation Sequencing Data Analysis.
Cui M, Bai M, Zheng L, Bao Y, Sun L, Yu C, Sun Y, Song Z, Wang G, Yu Z, Li Y, Huang Y
Biological & pharmaceutical bulletin 2021;44(10):1433-1444
Biological & pharmaceutical bulletin 2021;44(10):1433-1444
Suppression of DLBCL Progression by the E3 Ligase Trim35 Is Mediated by CLOCK Degradation and NK Cell Infiltration.
Tan X, Cao F, Tang F, Lu C, Yu Q, Feng S, Yang Z, Chen S, He X, He J, Weng L, Sun L
Journal of immunology research 2021;2021:9995869
Journal of immunology research 2021;2021:9995869
TNPO1-Mediated Nuclear Import of FUBP1 Contributes to Tumor Immune Evasion by Increasing NRP1 Expression in Cervical Cancer.
Yang B, Chen J, Teng Y
Journal of immunology research 2021;2021:9994004
Journal of immunology research 2021;2021:9994004
MiR-21-3p Inhibits Adipose Browning by Targeting FGFR1 and Aggravates Atrial Fibrosis in Diabetes.
Pan JA, Lin H, Yu JY, Zhang HL, Zhang JF, Wang CQ, Gu J
Oxidative medicine and cellular longevity 2021;2021:9987219
Oxidative medicine and cellular longevity 2021;2021:9987219
PIN1 Protects Hair Cells and Auditory HEI-OC1 Cells against Senescence by Inhibiting the PI3K/Akt/mTOR Pathway.
Zhang Y, Lv Z, Liu Y, Cao H, Yang J, Wang B
Oxidative medicine and cellular longevity 2021;2021:9980444
Oxidative medicine and cellular longevity 2021;2021:9980444
Lipidomic Alterations and PPARα Activation Induced by Resveratrol Lead to Reduction in Lesion Size in Endometriosis Models.
Chen Z, Wang C, Lin C, Zhang L, Zheng H, Zhou Y, Li X, Li C, Zhang X, Yang X, Guan M, Xi Y
Oxidative medicine and cellular longevity 2021;2021:9979953
Oxidative medicine and cellular longevity 2021;2021:9979953
Y-Box Binding Protein 1 Regulates Angiogenesis in Bladder Cancer via miR-29b-3p-VEGFA Pathway.
Gao D, Niu Q, Gong Y, Guo Q, Zhang S, Wang Y, Liu S, Wang H, Svatek R, Rodriguez R, Ma J, Wang Z
Journal of oncology 2021;2021:9913015
Journal of oncology 2021;2021:9913015
VIP Stabilizes the Cytoskeleton of Schlemm's Canal Endothelia via Reducing Caspase-3 Mediated ZO-1 Endolysosomal Degradation.
Lou X, Mou Q, Zhao B, Huang J, Yao K, Luo Z, Ye M, Hu Y, Duan Q, Li X, Wen Z, Chen Z, Zhang H, Zhao Y
Oxidative medicine and cellular longevity 2021;2021:9397960
Oxidative medicine and cellular longevity 2021;2021:9397960
Effect and Mechanism of LRP6 on Cardiac Myocyte Ferroptosis in Myocardial Infarction.
Li RL, Fan CH, Gong SY, Kang S
Oxidative medicine and cellular longevity 2021;2021:8963987
Oxidative medicine and cellular longevity 2021;2021:8963987
Tetrandrine Ameliorates Myocardial Ischemia Reperfusion Injury through miR-202-5p/TRPV2.
Zhao W, Wu Y, Ye F, Huang S, Chen H, Zhou R, Jiang W
BioMed research international 2021;2021:8870674
BioMed research international 2021;2021:8870674
P2X7 Receptor Induces Pyroptotic Inflammation and Cartilage Degradation in Osteoarthritis via NF-κB/NLRP3 Crosstalk.
Li Z, Huang Z, Zhang H, Lu J, Tian Y, Wei Y, Yang Y, Bai L
Oxidative medicine and cellular longevity 2021;2021:8868361
Oxidative medicine and cellular longevity 2021;2021:8868361
Oleanolic Acid Induces Autophagy and Apoptosis via the AMPK-mTOR Signaling Pathway in Colon Cancer.
Hu C, Cao Y, Li P, Tang X, Yang M, Gu S, Xiong K, Li T, Xiao T
Journal of oncology 2021;2021:8281718
Journal of oncology 2021;2021:8281718
Protective Effect of Xiao-Xu-Ming Decoction-Mediated Inhibition of ROS/NLRP3 Axis on Lipopolysaccharide-Induced Acute Lung Injury In Vitro and In Vivo.
Xiang Y, Cai M, Li X, Bao X, Cai D
Evidence-based complementary and alternative medicine : eCAM 2021;2021:8257495
Evidence-based complementary and alternative medicine : eCAM 2021;2021:8257495
Functional Analysis of Ectodysplasin-A Mutations in X-Linked Nonsyndromic Hypodontia and Possible Involvement of X-Chromosome Inactivation.
Pan Y, Lu T, Peng L, Zeng Q, Huang X, Yao X, Wu B, Xiong F
Stem cells international 2021;2021:7653013
Stem cells international 2021;2021:7653013
Wenxin Granules Regulate Endoplasmic Reticulum Stress Unfolded Protein Response and Improve Ventricular Remodeling on Rats with Myocardial Infarction.
Liu K, Lv M, Ji X, Lou L, Nie B, Zhao J, Wu A, Zhao M
Evidence-based complementary and alternative medicine : eCAM 2021;2021:7375549
Evidence-based complementary and alternative medicine : eCAM 2021;2021:7375549
Limonin Inhibits IL-1β-Induced Inflammation and Catabolism in Chondrocytes and Ameliorates Osteoarthritis by Activating Nrf2.
Jin J, Lv X, Wang B, Ren C, Jiang J, Chen H, Chen X, Gu M, Pan Z, Tian N, Wu A, Sun L, Gao W, Wang X, Zhang X, Wu Y, Zhou Y
Oxidative medicine and cellular longevity 2021;2021:7292512
Oxidative medicine and cellular longevity 2021;2021:7292512
Pentoxifylline Can Reduce the Inflammation Caused by LPS after Inhibiting Autophagy in RAW264.7 Macrophage Cells.
Ruan D, Deng S, Liu Z, He J
BioMed research international 2021;2021:6698366
BioMed research international 2021;2021:6698366
RBM23 Drives Hepatocellular Carcinoma by Activating NF-κB Signaling Pathway.
Han H, Lin T, Fang Z, Zhou G
BioMed research international 2021;2021:6697476
BioMed research international 2021;2021:6697476
Ganoderma lucidum Spore Polysaccharide Inhibits the Growth of Hepatocellular Carcinoma Cells by Altering Macrophage Polarity and Induction of Apoptosis.
Song M, Li ZH, Gu HS, Tang RY, Zhang R, Zhu YL, Liu JL, Zhang JJ, Wang LY
Journal of immunology research 2021;2021:6696606
Journal of immunology research 2021;2021:6696606
Dendrobium officinale Regulates Fatty Acid Metabolism to Ameliorate Liver Lipid Accumulation in NAFLD Mice.
Lei SS, Zhang NY, Zhou FC, He X, Wang HY, Li LZ, Zheng X, Dong YJ, Luo R, Li B, Jin HY, Yu QX, Lv GY, Chen SH
Evidence-based complementary and alternative medicine : eCAM 2021;2021:6689727
Evidence-based complementary and alternative medicine : eCAM 2021;2021:6689727
Nardosinone Alleviates Parkinson's Disease Symptoms in Mice by Regulating Dopamine D2 Receptor.
Bian LH, Yao ZW, Zhao CB, Li QY, Shi JL, Guo JY
Evidence-based complementary and alternative medicine : eCAM 2021;2021:6686965
Evidence-based complementary and alternative medicine : eCAM 2021;2021:6686965
Ferroportin-Dependent Iron Homeostasis Protects against Oxidative Stress-Induced Nucleus Pulposus Cell Ferroptosis and Ameliorates Intervertebral Disc Degeneration In Vivo.
Lu S, Song Y, Luo R, Li S, Li G, Wang K, Liao Z, Wang B, Ke W, Xiang Q, Chen C, Wu X, Zhang Y, Ling L, Yang C
Oxidative medicine and cellular longevity 2021;2021:6670497
Oxidative medicine and cellular longevity 2021;2021:6670497
Melatonin Alleviates Contrast-Induced Acute Kidney Injury by Activation of Sirt3.
Zhang C, Suo M, Liu L, Qi Y, Zhang C, Xie L, Zheng X, Ma C, Li J, Yang J, Bu P
Oxidative medicine and cellular longevity 2021;2021:6668887
Oxidative medicine and cellular longevity 2021;2021:6668887
Exercise Reduces Morphine-Induced Hyperalgesia and Antinociceptive Tolerance.
Gong X, Fan R, Zhu Q, Ye X, Chen Y, Zhang M
BioMed research international 2021;2021:6667474
BioMed research international 2021;2021:6667474
Identification of Immune-Related Prognostic Biomarkers Associated with HPV-Positive Head and Neck Squamous Cell Carcinoma.
Chen Y, Nie J, Li X, Fan T, Deng X, Liang D, Song G
Journal of immunology research 2021;2021:6661625
Journal of immunology research 2021;2021:6661625
Tantalum Particles Induced Cytotoxic and Inflammatory Effects in Human Monocytes.
Yang Y, Zhang Y, Kang Y, Hu C, Zhang Y, Liang H, You J, Shao L
BioMed research international 2021;2021:6658498
BioMed research international 2021;2021:6658498
Serum Exosomes Derived from Irritable Bowel Syndrome Patient Increase Cell Permeability via Regulating miR-148b-5p/RGS2 Signaling in Human Colonic Epithelium Cells.
Xing Y, Xue S, Wu J, Zhou J, Xing F, Li T, Nie X
Gastroenterology research and practice 2021;2021:6655900
Gastroenterology research and practice 2021;2021:6655900
CDK12 Promotes Cervical Cancer Progression through Enhancing Macrophage Infiltration.
Yang B, Chen J, Teng Y
Journal of immunology research 2021;2021:6645885
Journal of immunology research 2021;2021:6645885
Oxalate Activates Autophagy to Induce Ferroptosis of Renal Tubular Epithelial Cells and Participates in the Formation of Kidney Stones.
Song Q, Liao W, Chen X, He Z, Li, Li B, Liu J, Liu L, Xiong Y, Song C, Yang S
Oxidative medicine and cellular longevity 2021;2021:6630343
Oxidative medicine and cellular longevity 2021;2021:6630343
HO-1/CO Maintains Intestinal Barrier Integrity through NF-κB/MLCK Pathway in Intestinal HO-1-/- Mice.
Zhang Z, Zhang L, Zhang Q, Liu B, Li F, Xin Y, Duan Z
Oxidative medicine and cellular longevity 2021;2021:6620873
Oxidative medicine and cellular longevity 2021;2021:6620873
Babao Dan Reverses Multiple-Drug Resistance in Gastric Cancer Cells via Triggering Apoptosis and Autophagy and Inhibiting PI3K/AKT/mTOR Signaling.
Zhao J, Lan W, Peng J, Guan B, Liu J, Zhang M, Zhan Z, Lin J
Evidence-based complementary and alternative medicine : eCAM 2021;2021:5631942
Evidence-based complementary and alternative medicine : eCAM 2021;2021:5631942
lncRNA HHIP-AS1 Promotes the Osteogenic Differentiation Potential and Inhibits the Migration Ability of Periodontal Ligament Stem Cells.
Qin Q, Yang H, Zhang C, Han X, Guo J, Fan Z, Guo J
Stem cells international 2021;2021:5595580
Stem cells international 2021;2021:5595580
Tubeimoside I Ameliorates Myocardial Ischemia-Reperfusion Injury through SIRT3-Dependent Regulation of Oxidative Stress and Apoptosis.
Lv D, Luo M, Cheng Z, Wang R, Yang X, Guo Y, Huang L, Li X, Huang B, Shen J, Luo S, Yan J
Oxidative medicine and cellular longevity 2021;2021:5577019
Oxidative medicine and cellular longevity 2021;2021:5577019
Heat Killed Salmonella typhimurium Protects Intestine Against Radiation Injury Through Wnt Signaling Pathway.
Chen Y, Cao K, Liu H, Liu T, Liu L, Qin H, Liao Z, Hu X, Li B, Liu C, Cai J, Cui J, Gao F, Yang Y
Journal of oncology 2021;2021:5550956
Journal of oncology 2021;2021:5550956
Essential Oil-Rich Chinese Formula Luofushan-Baicao Oil Inhibits the Infection of Influenza A Virus through the Regulation of NF-κB P65 and IRF3 Activation.
Mao X, Gu S, Sang H, Ye Y, Li J, Teng Y, Zhang F, Ma Q, Jiang P, Yang Z, Huang W, Liu S
Evidence-based complementary and alternative medicine : eCAM 2021;2021:5547424
Evidence-based complementary and alternative medicine : eCAM 2021;2021:5547424
TIPE1 Suppresses Growth and Metastasis of Ovarian Cancer.
Zhang Z, Chang M, Song X, Wang K, Sun W, Ma H, Yan X, Sun Y, Song X, Xie L
Journal of oncology 2021;2021:5538911
Journal of oncology 2021;2021:5538911
Pleckstrin-2 as a Prognostic Factor and Mediator of Gastric Cancer Progression.
Wang J, He Z, Sun B, Huang W, Xiang J, Chen Z, Li Z, Gu X
Gastroenterology research and practice 2021;2021:5527387
Gastroenterology research and practice 2021;2021:5527387
LuQi Formula Regulates NLRP3 Inflammasome to Relieve Myocardial-Infarction-Induced Cardiac Remodeling in Mice.
Zhang X, Zhao D, Feng J, Yang X, Lan Z, Yang T, Kong X, Qu H, Zhou H
Evidence-based complementary and alternative medicine : eCAM 2021;2021:5518083
Evidence-based complementary and alternative medicine : eCAM 2021;2021:5518083
CKAP2L, as an Independent Risk Factor, Closely Related to the Prognosis of Glioma.
Zhu L, Zheng Y, Hu R, Hu C
BioMed research international 2021;2021:5486131
BioMed research international 2021;2021:5486131
Design, Synthesis, and Biological Evaluation of a Novel Aminothiol Compound as Potential Radioprotector.
Li X, Wang X, Miao L, Guo Y, Yuan R, Ren J, Huang Y, Tian H
Oxidative medicine and cellular longevity 2021;2021:4714649
Oxidative medicine and cellular longevity 2021;2021:4714649
The Dietary Supplement γ-Oryzanol Attenuates Hepatic Ischemia Reperfusion Injury via Inhibiting Endoplasmic Reticulum Stress and HMGB1/NLRP3 Inflammasome.
Du Y, Zhong F, Cheng H, Li T, Chen Y, Tan P, Huang M, Liang T, Liu Y, Xia X, Fu W
Oxidative medicine and cellular longevity 2021;2021:4628050
Oxidative medicine and cellular longevity 2021;2021:4628050
MCC950, the NLRP3 Inhibitor, Protects against Cartilage Degradation in a Mouse Model of Osteoarthritis.
Ni B, Pei W, Qu Y, Zhang R, Chu X, Wang Y, Huang X, You H
Oxidative medicine and cellular longevity 2021;2021:4139048
Oxidative medicine and cellular longevity 2021;2021:4139048
Hypoxia Enhances Activity and Malignant Behaviors of Colorectal Cancer Cells through the STAT3/MicroRNA-19a/PTEN/PI3K/AKT Axis.
Tang Y, Weng X, Liu C, Li X, Chen C
Analytical cellular pathology (Amsterdam) 2021;2021:4132488
Analytical cellular pathology (Amsterdam) 2021;2021:4132488
ULK1 Suppresses Osteoclast Differentiation and Bone Resorption via Inhibiting Syk-JNK through DOK3.
Zhang Y, Zhang S, Wang Y, Yang Z, Chen Z, Wen N, Yang M, Huang Z, Xie Y, Cai L
Oxidative medicine and cellular longevity 2021;2021:2896674
Oxidative medicine and cellular longevity 2021;2021:2896674
Danhong Injection and Trimetazidine Protect Cardiomyocytes and Enhance Calcium Handling after Myocardial Infarction.
Zhang J, Shi X, Gao J, Zhou R, Guo F, Zhang Y, Fan F, Zhai Q, Sun M, Yang H
Evidence-based complementary and alternative medicine : eCAM 2021;2021:2480465
Evidence-based complementary and alternative medicine : eCAM 2021;2021:2480465
Luteolin Improves Cyclophosphamide-Induced Cystitis through TXNIP/NLRP3 and NF-κB Pathways.
Zhang H, Zhao J, Lu Q, Sun B, Liu X, Yang C, Li S, Li L, Yi S, Yang Z, Xu J
Evidence-based complementary and alternative medicine : eCAM 2021;2021:1718709
Evidence-based complementary and alternative medicine : eCAM 2021;2021:1718709
Mitoquinone Protects Podocytes from Angiotensin II-Induced Mitochondrial Dysfunction and Injury via the Keap1-Nrf2 Signaling Pathway.
Zhu Z, Liang W, Chen Z, Hu J, Feng J, Cao Y, Ma Y, Ding G
Oxidative medicine and cellular longevity 2021;2021:1394486
Oxidative medicine and cellular longevity 2021;2021:1394486
Ivabradine Ameliorates Cardiac Function in Heart Failure with Preserved and Reduced Ejection Fraction via Upregulation of miR-133a.
Shao S, Zhang Y, Gong M, Yang Q, Yuan M, Yuan M, Suo Y, Wang X, Li Y, Bao Q, Li G
Oxidative medicine and cellular longevity 2021;2021:1257283
Oxidative medicine and cellular longevity 2021;2021:1257283
circGLI3 Inhibits Oxidative Stress by Regulating the miR-339-5p/VEGFA Axis in IPEC-J2 Cells.
Li ZX, Wang LX, Zhang Y, Chen W, Zeng YQ
BioMed research international 2021;2021:1086206
BioMed research international 2021;2021:1086206
Inhibiting PP2Acα Promotes the Malignant Phenotype of Gastric Cancer Cells through the ATM/METTL3 Axis.
Cheng Z, Gao S, Liang X, Lian C, Chen J, Fang C
BioMed research international 2021;2021:1015293
BioMed research international 2021;2021:1015293
An Integrated Transcriptomics and Proteomics Analysis Implicates lncRNA MALAT1 in the Regulation of Lipid Metabolism.
Wang H, Zhang Y, Guan X, Li X, Zhao Z, Gao Y, Zhang X, Chen R
Molecular & cellular proteomics : MCP 2021;20:100141
Molecular & cellular proteomics : MCP 2021;20:100141
Lack of WDFY4 Aggravates Ovalbumin-Induced Asthma via Enhanced Th2 Cell Differentiation.
Li Y, Wang A, Long F, Gao F, Gao S, Wei S, Liu A, Li X, Sun W, Li J, Liu Q
International archives of allergy and immunology 2021;182(11):1089-1096
International archives of allergy and immunology 2021;182(11):1089-1096
Long noncoding RNA CEBPA-DT promotes cisplatin chemo-resistance through CEBPA/BCL2 mediated apoptosis in oral squamous cellular cancer.
Qiao X, Liu J, Zhu L, Song R, Zhong M, Guo Y
International journal of medical sciences 2021;18(16):3728-3737
International journal of medical sciences 2021;18(16):3728-3737
The expression and clinical significance of TPM4 in hepatocellular carcinoma.
Li L, Ye T, Zhang Q, Li X, Ma L, Yan J
International journal of medical sciences 2021;18(1):169-175
International journal of medical sciences 2021;18(1):169-175
Dual-specificity Phosphatase 9 protects against Cardiac Hypertrophy by targeting ASK1.
Jiang L, Ren L, Guo X, Zhao J, Zhang H, Chen S, Le S, Liu H, Ye P, Chen M, Xia J
International journal of biological sciences 2021;17(9):2193-2204
International journal of biological sciences 2021;17(9):2193-2204
GABAB receptor inhibits tumor progression and epithelial-mesenchymal transition via the regulation of Hippo/YAP1 pathway in colorectal cancer.
Wang H, Zhang H, Sun Z, Chen W, Miao C
International journal of biological sciences 2021;17(8):1953-1962
International journal of biological sciences 2021;17(8):1953-1962
MicroRNA-135b/CAMK2D Axis Contribute to Malignant Progression of Gastric Cancer through EMT Process Remodeling.
Huangfu L, He Q, Han J, Shi J, Li X, Cheng X, Guo T, Du H, Zhang W, Gao X, Luan F, Xing X, Ji J
International journal of biological sciences 2021;17(8):1940-1952
International journal of biological sciences 2021;17(8):1940-1952
NDRG1 regulates Filopodia-induced Colorectal Cancer invasiveness via modulating CDC42 activity.
Aikemu B, Shao Y, Yang G, Ma J, Zhang S, Yang X, Hong H, Yesseyeva G, Huang L, Jia H, Wang C, Zang L, Sun J, Zheng M
International journal of biological sciences 2021;17(7):1716-1730
International journal of biological sciences 2021;17(7):1716-1730
YY1-modulated long non-coding RNA SNHG12 promotes gastric cancer metastasis by activating the miR-218-5p/YWHAZ axis.
Zhang T, Beeharry MK, Wang Z, Zhu Z, Li J, Li C
International journal of biological sciences 2021;17(7):1629-1643
International journal of biological sciences 2021;17(7):1629-1643
PAK5-mediated AIF phosphorylation inhibits its nuclear translocation and promotes breast cancer tumorigenesis.
Xing Y, Li Y, Hu B, Han F, Zhao X, Zhang H, Li Y, Li D, Li J, Jin F, Li F
International journal of biological sciences 2021;17(5):1315-1327
International journal of biological sciences 2021;17(5):1315-1327
Aurka deficiency in the intestinal epithelium promotes age-induced obesity via propionate-mediated AKT activation.
Sun N, Meng F, Zhao J, Li X, Li R, Han J, Chen X, Cheng W, Yang X, Kou Y, Zheng K, Yang J, Ikezoe T
International journal of biological sciences 2021;17(5):1302-1314
International journal of biological sciences 2021;17(5):1302-1314
Characteristics of the PI3K/AKT and MAPK/ERK pathways involved in the maintenance of self-renewal in lung cancer stem-like cells.
Li J, Wang J, Xie D, Pei Q, Wan X, Xing HR, Ye T
International journal of biological sciences 2021;17(5):1191-1202
International journal of biological sciences 2021;17(5):1191-1202
Novel biomarkers for post-contrast acute kidney injury identified from long non-coding RNA expression profiles.
Chen G, Liu B, Chen S, Li H, Liu J, Mai Z, Chen E, Zhou C, Sun G, Guo Z, Lei L, Huang S, Zhang L, Li M, Tan N, Li H, Liao Y, Liu J, Chen J, Liu Y
International journal of biological sciences 2021;17(3):882-896
International journal of biological sciences 2021;17(3):882-896
Linc-KILH potentiates Notch1 signaling through inhibiting KRT19 phosphorylation and promotes the malignancy of hepatocellular carcinoma.
Zhang X, Xu X, Zhang Z, Xue C, Kong Z, Wu S, Yun X, Fu Y, Zhu C, Qin X
International journal of biological sciences 2021;17(3):768-780
International journal of biological sciences 2021;17(3):768-780
ITGB1 enhances the Radioresistance of human Non-small Cell Lung Cancer Cells by modulating the DNA damage response and YAP1-induced Epithelial-mesenchymal Transition.
Li Y, Sun C, Tan Y, Zhang H, Li Y, Zou H
International journal of biological sciences 2021;17(2):635-650
International journal of biological sciences 2021;17(2):635-650
Inhibition of PI3K/AKT signaling via ROS regulation is involved in Rhein-induced apoptosis and enhancement of oxaliplatin sensitivity in pancreatic cancer cells.
Liu Y, Shi C, He Z, Zhu F, Wang M, He R, Zhao C, Shi X, Zhou M, Pan S, Gao Y, Li X, Qin R
International journal of biological sciences 2021;17(2):589-602
International journal of biological sciences 2021;17(2):589-602
SOX13/TRIM11/YAP axis promotes the proliferation, migration and chemoresistance of anaplastic thyroid cancer.
Tang J, Tian Z, Liao X, Wu G
International journal of biological sciences 2021;17(2):417-429
International journal of biological sciences 2021;17(2):417-429
MAD2B-mediated cell cycle reentry of podocytes is involved in the pathogenesis of FSGS.
Bao D, Su H, Lei CT, Tang H, Ye C, Xiong W, He FF, Lin JH, Hammes HP, Zhang C
International journal of biological sciences 2021;17(15):4396-4408
International journal of biological sciences 2021;17(15):4396-4408
Discovery of a novel HDACi structure that inhibits the proliferation of ovarian cancer cells in vivo and in vitro.
Bai M, Cui M, Li M, Yao X, Wu Y, Zheng L, Sun L, Song Q, Wang S, Liu L, Yu C, Huang Y
International journal of biological sciences 2021;17(13):3493-3507
International journal of biological sciences 2021;17(13):3493-3507
Downregulation of miR‑214-3p attenuates mesangial hypercellularity by targeting PTEN‑mediated JNK/c-Jun signaling in IgA nephropathy.
Li Y, Xia M, Peng L, Liu H, Chen G, Wang C, Yuan D, Liu Y, Liu H
International journal of biological sciences 2021;17(13):3343-3355
International journal of biological sciences 2021;17(13):3343-3355
Genome-scale CRISPRa screening identifies MTX1 as a contributor for sorafenib resistance in hepatocellular carcinoma by augmenting autophagy.
Li L, Yu S, Hu Q, Hai Y, Li Y
International journal of biological sciences 2021;17(12):3133-3144
International journal of biological sciences 2021;17(12):3133-3144
CXCL16 Promotes Gastric Cancer Tumorigenesis via ADAM10-Dependent CXCL16/CXCR6 Axis and Activates Akt and MAPK Signaling Pathways.
Han J, Fu R, Chen C, Cheng X, Guo T, Huangfu L, Li X, Du H, Xing X, Ji J
International journal of biological sciences 2021;17(11):2841-2852
International journal of biological sciences 2021;17(11):2841-2852
Ailanthus Altissima-derived Ailanthone enhances Gastric Cancer Cell Apoptosis by Inducing the Repression of Base Excision Repair by Downregulating p23 Expression.
Wang CM, Li HF, Wang XK, Li WG, Su Q, Xiao X, Hao TF, Chen W, Zhang YW, Zhang HY, Wu W, Hu ZR, Zhao GY, Huo MY, He YL, Zhang CH
International journal of biological sciences 2021;17(11):2811-2825
International journal of biological sciences 2021;17(11):2811-2825
Novel Functions of CD147 in the Mitochondria Exacerbates Melanoma Metastasis.
Lu L, Zhang J, Gan P, Wu L, Zhang X, Peng C, Zhou J, Chen X, Su J
International journal of biological sciences 2021;17(1):285-297
International journal of biological sciences 2021;17(1):285-297
COP9 Signalosome Subunit 3 Restricts Neuroinflammatory Responses During Cerebral Ischemia/Reperfusion Injury Through Stabilizing Suppressor of Cytokine Signaling 3 Protein.
Liang E, Li X, Fu W, Zhao C, Yang B, Yang Z
Neuropsychiatric disease and treatment 2021;17:1217-1227
Neuropsychiatric disease and treatment 2021;17:1217-1227
Loss of miR-1469 expression mediates melanoma cell migration and invasion.
DiVincenzo MJ, Barricklow Z, Schwarz E, Moufawad M, Howard JH, Yu L, Chung C, Gru AA, Carson WE 3rd
PloS one 2021;16(9):e0256629
PloS one 2021;16(9):e0256629
A novel mouse line with epididymal initial segment-specific expression of Cre recombinase driven by the endogenous Lcn9 promoter.
Gong QQ, Wang X, Dou ZL, Zhang KY, Liu XG, Gao JG, Sun XY
PloS one 2021;16(7):e0254802
PloS one 2021;16(7):e0254802
Modulation of inflammatory responses by fractalkine signaling in microglia.
Inoue K, Morimoto H, Ohgidani M, Ueki T
PloS one 2021;16(5):e0252118
PloS one 2021;16(5):e0252118
Harmine inhibits breast cancer cell migration and invasion by inducing the degradation of Twist1.
Nafie E, Lolarga J, Lam B, Guo J, Abdollahzadeh E, Rodriguez S, Glackin C, Liu J
PloS one 2021;16(2):e0247652
PloS one 2021;16(2):e0247652
High expression of ENPP1 in high-grade serous ovarian carcinoma predicts poor prognosis and as a molecular therapy target.
Wang H, Ye F, Zhou C, Cheng Q, Chen H
PloS one 2021;16(2):e0245733
PloS one 2021;16(2):e0245733
Downregulation of RAB7 and Caveolin-1 increases MMP-2 activity in renal tubular epithelial cells under hypoxic conditions.
Yu W, Ke X, Li M, Ye P, Peng J, Li H
Open medicine (Warsaw, Poland) 2021;16(1):1428-1437
Open medicine (Warsaw, Poland) 2021;16(1):1428-1437
Copper Nanoparticles Induce Oxidative Stress via the Heme Oxygenase 1 Signaling Pathway in vitro Studies.
Zou L, Cheng G, Xu C, Liu H, Wang Y, Li N, Fan X, Zhu C, Xia W
International journal of nanomedicine 2021;16:1565-1573
International journal of nanomedicine 2021;16:1565-1573
Convallatoxin Promotes M2 Macrophage Polarization to Attenuate Atherosclerosis Through PPARγ-Integrin αvβ5 Signaling Pathway.
Zhang Y, Shi X, Han J, Peng W, Fang Z, Zhou Y, Xu X, Lin J, Xiao F, Zhao L, Lin Y
Drug design, development and therapy 2021;15:803-812
Drug design, development and therapy 2021;15:803-812
Astrocyte Pannexin 1 Suppresses LPS-Induced Inflammatory Responses to Protect Neuronal SH-SY5Y Cells.
Ling ZM, Wang Q, Ma Y, Xue P, Gu Y, Cao MH, Wei ZY
Frontiers in cellular neuroscience 2021;15:710820
Frontiers in cellular neuroscience 2021;15:710820
Tetramethylpyrazine Alleviates Behavioral and Psychological Symptoms of Dementia Through Facilitating Hippocampal Synaptic Plasticity in Rats With Chronic Cerebral Hypoperfusion.
Tan Z, Qiu J, Zhang Y, Yang Q, Yin X, Li J, Liu G, Li H, Yang G
Frontiers in neuroscience 2021;15:646537
Frontiers in neuroscience 2021;15:646537
The Ghrelin/Growth Hormone Secretagogue Receptor System Is Involved in the Rapid and Sustained Antidepressant-Like Effect of Paeoniflorin.
Zhang Y, Zhu MZ, Qin XH, Zeng YN, Zhu XH
Frontiers in neuroscience 2021;15:631424
Frontiers in neuroscience 2021;15:631424
Isoquercetin Improves Inflammatory Response in Rats Following Ischemic Stroke.
Shi Y, Chen X, Liu J, Fan X, Jin Y, Gu J, Liang J, Liang X, Wang C
Frontiers in neuroscience 2021;15:555543
Frontiers in neuroscience 2021;15:555543
Activation of GPR18 by Resolvin D2 Relieves Pain and Improves Bladder Function in Cyclophosphamide-Induced Cystitis Through Inhibiting TRPV1.
Lu Q, Yang Y, Zhang H, Chen C, Zhao J, Yang Z, Fan Y, Li L, Feng H, Zhu J, Yi S
Drug design, development and therapy 2021;15:4687-4699
Drug design, development and therapy 2021;15:4687-4699
Bardoxolone-Methyl Prevents Oxidative Stress-Mediated Apoptosis and Extracellular Matrix Degradation in vitro and Alleviates Osteoarthritis in vivo.
Pang Z, Jiang Z, Zhu R, Song C, Tang H, Cao L, Guo C
Drug design, development and therapy 2021;15:3735-3747
Drug design, development and therapy 2021;15:3735-3747
Puerarin Alleviates UUO-Induced Inflammation and Fibrosis by Regulating the NF-κB P65/STAT3 and TGFβ1/Smads Signaling Pathways.
Wang J, Ge S, Wang Y, Liu Y, Qiu L, Li J, Huang X, Sun L
Drug design, development and therapy 2021;15:3697-3708
Drug design, development and therapy 2021;15:3697-3708
Pentamidine Inhibits Ovarian Cancer Cell Proliferation and Migration by Maintaining Stability of PTEN in vitro.
Wu Y, Zhang Z, Kou Z
Drug design, development and therapy 2021;15:2857-2868
Drug design, development and therapy 2021;15:2857-2868
The Effects of M1/M2 Macrophages on the mRNA Expression Profile of Diabetic Glomerular Endothelial Cells.
Li Y, Yu W, He M, Yuan F
Nephron 2021;145(5):568-578
Nephron 2021;145(5):568-578
Inhibition of TGF-β2-induced migration and epithelial-mesenchymal transition in ARPE-19 by sulforaphane.
Huang YB, Liu PP, Zheng H, Yang XX, Yang CC, Liu Y, Liu Y
International journal of ophthalmology 2021;14(7):973-980
International journal of ophthalmology 2021;14(7):973-980
Effect of luteolin on apoptosis and vascular endothelial growth factor in human choroidal melanoma cells.
Shi ML, Chen YF, Liao HF
International journal of ophthalmology 2021;14(2):186-193
International journal of ophthalmology 2021;14(2):186-193
Maxing Shigan Decoction Mitigates Mycoplasma pneumonia-Induced Pyroptosis in A549 Cells via the NLRP3 Inflammasome.
Liu F, Liu T, Sun M, Zhou J, Xue F, Chen S, Chen J, Zhang L
Infection and drug resistance 2021;14:859-867
Infection and drug resistance 2021;14:859-867
LncRNA MCTP1-AS1 Regulates EMT Process in Endometrial Cancer by Targeting the miR-650/SMAD7 Axis.
Gao Q, Huang Q, Li F, Luo F
OncoTargets and therapy 2021;14:751-761
OncoTargets and therapy 2021;14:751-761
Engeletin Protects Against TNF-α-Induced Apoptosis and Reactive Oxygen Species Generation in Chondrocytes and Alleviates Osteoarthritis in vivo.
Wang H, Jiang Z, Pang Z, Qi G, Hua B, Yan Z, Yuan H
Journal of inflammation research 2021;14:745-760
Journal of inflammation research 2021;14:745-760
Proteomic Profiling of Astrocytic O-GlcNAc Transferase-Related Proteins in the Medial Prefrontal Cortex.
Fan J, Zhong QL, Mo R, Lu CL, Ren J, Mo JW, Guo F, Wen YL, Cao X
Frontiers in molecular neuroscience 2021;14:729975
Frontiers in molecular neuroscience 2021;14:729975
Neutrophil Extracellular Traps Augmented Alveolar Macrophage Pyroptosis via AIM2 Inflammasome Activation in LPS-Induced ALI/ARDS.
Li H, Li Y, Song C, Hu Y, Dai M, Liu B, Pan P
Journal of inflammation research 2021;14:4839-4858
Journal of inflammation research 2021;14:4839-4858
A c-Met Inhibitor Suppresses Osteosarcoma Progression via the ERK1/2 Pathway in Human Osteosarcoma Cells.
Chen W, Wu S, Huang Y, Zhang T, Dong H, Zheng X, Chen T, Gong X, Liu G, Zhao X
OncoTargets and therapy 2021;14:4791-4804
OncoTargets and therapy 2021;14:4791-4804
Fatty Acid-Binding Protein 4 (FABP4) Suppresses Proliferation and Migration of Endometrial Cancer Cells via PI3K/Akt Pathway.
Wu Z, Jeong JH, Ren C, Yang L, Ding L, Li F, Jiang D, Zhu Y, Lu J
OncoTargets and therapy 2021;14:3929-3942
OncoTargets and therapy 2021;14:3929-3942
miR-944 Suppresses EGF-Induced EMT in Colorectal Cancer Cells by Directly Targeting GATA6.
Tang J, Gao W, Liu G, Sheng W, Zhou J, Dong Q, Dong M
OncoTargets and therapy 2021;14:2311-2325
OncoTargets and therapy 2021;14:2311-2325
Prognostic Implications of the Complement Protein C1Q and Its Correlation with Immune Infiltrates in Osteosarcoma.
Huang H, Tan M, Zheng L, Yan G, Li K, Lu D, Cui X, He S, Lei D, Zhu B, Zhao J
OncoTargets and therapy 2021;14:1737-1751
OncoTargets and therapy 2021;14:1737-1751
An Apoptotic Gene Signature for the Prognosis of Hepatocellular Carcinoma.
Chen K, Zhu P, Liao Y, Yan L, Feng R, Zhai W
OncoTargets and therapy 2021;14:1589-1604
OncoTargets and therapy 2021;14:1589-1604
Expression and Functional Relevance of ANXA1 in Hypopharyngeal Carcinoma with Lymph Node Metastasis.
Li L, Wang Z, Lu T, Li Y, Pan M, Yu D, Hu G
OncoTargets and therapy 2021;14:1387-1399
OncoTargets and therapy 2021;14:1387-1399
Circular RNA ERBB2 Contributes to Proliferation and Migration of Airway Smooth Muscle Cells via miR-98-5p/IGF1R Signaling in Asthma.
Huang JQ, Wang F, Wang LT, Li YM, Lu JL, Chen JY
Journal of asthma and allergy 2021;14:1197-1207
Journal of asthma and allergy 2021;14:1197-1207
FUT7 Promotes the Epithelial-Mesenchymal Transition and Immune Infiltration in Bladder Urothelial Carcinoma.
Liu M, Zheng Q, Chen S, Liu J, Li S
Journal of inflammation research 2021;14:1069-1084
Journal of inflammation research 2021;14:1069-1084
The cardioprotective effect of the sodium-glucose cotransporter 2 inhibitor dapagliflozin in rats with isoproterenol-induced cardiomyopathy.
Wang FZ, Wei WB, Li X, Huo JY, Jiang WY, Wang HY, Qian P, Li ZZ, Zhou YB
American journal of translational research 2021;13(9):10950-10961
American journal of translational research 2021;13(9):10950-10961
Knockdown of VDAC1 alleviates the cognitive dysfunction secondary to sepsis-associated encephalopathy.
Cai M, Du B, Si Y, Miao J, Ge J, Zhang J, Song J, Bao H
American journal of translational research 2021;13(7):7538-7555
American journal of translational research 2021;13(7):7538-7555
Qi Ling decoction reduces gastric cancer cell metastasis by inhibiting MMP-9 through the PI3K/Akt signaling pathway.
Chen W, Zhang Y, Gu X, Qian P, Liu W, Shu P
American journal of translational research 2021;13(5):4591-4602
American journal of translational research 2021;13(5):4591-4602
Inhibition of mu-opioid receptor suppresses proliferation of hepatocellular carcinoma cells via CD147-p53-MAPK cascade signaling pathway.
Zhang JJ, Song CG, Dai JM, Zhang XQ, Lin P, Li L, Yang XM, Chen ZN
American journal of translational research 2021;13(5):3967-3986
American journal of translational research 2021;13(5):3967-3986
Positive Feedback Loop of Long Noncoding RNA OASL-IT1 and Innate Immune Response Restricts the Replication of Zika Virus in Epithelial A549 Cells.
Wang Y, Huo Z, Lin Q, Lin Y, Chen C, Huang Y, Huang C, Zhang J, He J, Liu C, Zhang P
Journal of innate immunity 2021;13(3):179-193
Journal of innate immunity 2021;13(3):179-193
Curcumin promotes the survival of ischemic random skin flaps via autophagy.
Tu Z, Jiang X, Li Y, Yang S, Lin D, Shi Y, Mao C, Zhang X, Lin C
American journal of translational research 2021;13(3):1337-1351
American journal of translational research 2021;13(3):1337-1351
TET2 mediated demethylation is involved in the protective effect of triptolide on podocytes.
Wan F, Tang YW, Tang XL, Li YY, Yang RC
American journal of translational research 2021;13(3):1233-1244
American journal of translational research 2021;13(3):1233-1244
Sevoflurane prevents pulmonary vascular remodeling and right ventricular dysfunction in pulmonary arterial hypertension in rats.
Zhai W, Li Y, Luo Y, Gao W, Liu S, Han J, Geng J
American journal of translational research 2021;13(10):11302-11315
American journal of translational research 2021;13(10):11302-11315
Dura cells in the etiopathogenesis of Crouzon syndrome: the effects of FGFR2 mutations in the dura cells on the proliferation of osteoblasts through the hippo/YAP mediated transcriptional regulation pathway.
Dong XH, Zhang MZ, Lai CZ, Li CC, Du L, Song GD, Zong XL, Jin XL
American journal of translational research 2021;13(10):11255-11270
American journal of translational research 2021;13(10):11255-11270
Combination effect of curcumin with docetaxel on the PI3K/AKT/mTOR pathway to induce autophagy and apoptosis in esophageal squamous cell carcinoma.
Deng L, Wu X, Zhu X, Yu Z, Liu Z, Wang J, Zheng Y
American journal of translational research 2021;13(1):57-72
American journal of translational research 2021;13(1):57-72
Downregulation of miRNA-451a Promotes the Differentiation of CD4+ T Cells towards Th2 Cells by Upregulating ETS1 in Childhood Asthma.
Wang T, Zhou Q, Shang Y
Journal of innate immunity 2021;13(1):38-48
Journal of innate immunity 2021;13(1):38-48
PARK2 attenuates house dust mite-induced inflammatory reaction, pyroptosis and barrier dysfunction in BEAS-2B cells by ubiquitinating NLRP3.
Ge X, Cai F, Shang Y, Chi F, Xiao H, Xu J, Fu Y, Bai C
American journal of translational research 2021;13(1):326-335
American journal of translational research 2021;13(1):326-335
AGTR1 Inhibits the Progression of Lung Adenocarcinoma.
Xiong L, Wei Y, Zhou X, Dai P, Cai Y, Zhou X, Xu M, Zhao J, Tang H
Cancer management and research 2021;13:8535-8550
Cancer management and research 2021;13:8535-8550
lncRNA AC007207.2 Promotes Malignant Properties of Osteosarcoma via the miR-1306-5p/SIRT7 Axis.
Dang Y, Zhou Y, Ou X, Wang Q, Wei D, Xie F
Cancer management and research 2021;13:7277-7288
Cancer management and research 2021;13:7277-7288
Stress Granules Modulate SYK to Cause Tau-Associated Neurocognitive Deterioration in 5XFAD Mouse After Anesthesia and Surgery.
Shen Y, Zhang T, Zhang Y, Wang Y, Yao J
Frontiers in aging neuroscience 2021;13:718701
Frontiers in aging neuroscience 2021;13:718701
Enriched Environment Attenuates Pyroptosis to Improve Functional Recovery After Cerebral Ischemia/Reperfusion Injury.
Liu J, Zheng J, Xu Y, Cao W, Wang J, Wang B, Zhao L, Zhang X, Liao W
Frontiers in aging neuroscience 2021;13:717644
Frontiers in aging neuroscience 2021;13:717644
MALAT-1 is Associated with the Doxorubicin Resistance in U-2OS Osteosarcoma Cells.
Liu C, Han X, Li B, Huang S, Zhou Z, Wang Z, Wang W
Cancer management and research 2021;13:6879-6889
Cancer management and research 2021;13:6879-6889
Calcitriol Alleviates MPP+- and MPTP-Induced Parthanatos Through the VDR/PARP1 Pathway in the Model of Parkinson's Disease.
Hu J, Wu J, Wan F, Kou L, Yin S, Sun Y, Li Y, Zhou Q, Wang T
Frontiers in aging neuroscience 2021;13:657095
Frontiers in aging neuroscience 2021;13:657095
Intranasal Transplantation of Human Neural Stem Cells Ameliorates Alzheimer's Disease-Like Pathology in a Mouse Model.
Lu MH, Ji WL, Chen H, Sun YY, Zhao XY, Wang F, Shi Y, Hu YN, Liu BX, Wu JW, Xu DE, Zheng JW, Liu CF, Ma QH
Frontiers in aging neuroscience 2021;13:650103
Frontiers in aging neuroscience 2021;13:650103
Long-Term Administration of Triterpenoids From Ganoderma lucidum Mitigates Age-Associated Brain Physiological Decline via Regulating Sphingolipid Metabolism and Enhancing Autophagy in Mice.
Zeng M, Qi L, Guo Y, Zhu X, Tang X, Yong T, Xie Y, Wu Q, Zhang M, Chen D
Frontiers in aging neuroscience 2021;13:628860
Frontiers in aging neuroscience 2021;13:628860
The Non-peptide Angiotensin-(1-7) Mimic AVE 0991 Attenuates Delayed Neurocognitive Recovery After Laparotomy by Reducing Neuroinflammation and Restoring Blood-Brain Barrier Integrity in Aged Rats.
Mi X, Cao Y, Li Y, Li Y, Hong J, He J, Liang Y, Yang N, Liu T, Han D, Kuang C, Han Y, Zhou Y, Liu Y, Shi C, Guo X, Li Z
Frontiers in aging neuroscience 2021;13:624387
Frontiers in aging neuroscience 2021;13:624387
Plakophilin-2 Promotes Lung Adenocarcinoma Development via Enhancing Focal Adhesion and Epithelial-Mesenchymal Transition.
Wu Y, Liu L, Shen X, Liu W, Ma R
Cancer management and research 2021;13:559-570
Cancer management and research 2021;13:559-570
KLF7 Promotes Gastric Carcinogenesis Through Regulation of ANTXR1.
Li Y, Wang Q, Wang D, Fu W
Cancer management and research 2021;13:5547-5557
Cancer management and research 2021;13:5547-5557
Columbamine-Mediated PTEN/AKT Signal Pathway Regulates the Progression of Glioma.
Niu HT, Liu Y, Wang YZ, Tian Y, Yang M, Jiang HS
Cancer management and research 2021;13:489-497
Cancer management and research 2021;13:489-497
The Preliminary Study for Postoperative Radiotherapy Survival Associated with RUNX3 and TLR9 Expression in Lung Cancer.
Gao C, Qiao T, Yuan S, Zhuang X
Cancer management and research 2021;13:4497-4507
Cancer management and research 2021;13:4497-4507
Overexpression of Taspase 1 Predicts Poor Prognosis in Patients with Hepatocellular Carcinoma.
Jiang J, Liu B, Liu R, Yang W
Cancer management and research 2021;13:2517-2537
Cancer management and research 2021;13:2517-2537
Identification of TRIM56 as a Potential Biomarker for Lung Adenocarcinoma.
Lu K, Sui Y, Fu L
Cancer management and research 2021;13:2201-2213
Cancer management and research 2021;13:2201-2213
Identification and validation of the clinical roles of the VHL-related LncRNAs in clear cell renal cell carcinoma.
Yang W, Zhou J, Zhang K, Li L, Xu Y, Ma K, Xie H, Cai L, Gong Y, Gong K
Journal of Cancer 2021;12(9):2702-2714
Journal of Cancer 2021;12(9):2702-2714
SCARA5 inhibits gastric cancer progression via epithelial-mesenchymal transition suppression.
Zhang H, Liu C, Wang X, Wang Y, Zheng J
Journal of Cancer 2021;12(8):2412-2421
Journal of Cancer 2021;12(8):2412-2421
Peri-tumoral brain edema associated with glioblastoma correlates with tumor recurrence.
Qin X, Liu R, Akter F, Qin L, Xie Q, Li Y, Qiao H, Zhao W, Jian Z, Liu R, Wu S
Journal of Cancer 2021;12(7):2073-2082
Journal of Cancer 2021;12(7):2073-2082
Long non-coding RNA SNHG25 promotes epithelial ovarian cancer progression by up-regulating COMP.
Liu Y, Xu B, Liu M, Qiao H, Zhang S, Qiu J, Ying X
Journal of Cancer 2021;12(6):1660-1668
Journal of Cancer 2021;12(6):1660-1668
Decreased interferon regulatory factor 6 expression due to DNA hypermethylation predicts an unfavorable prognosis in clear cell renal cell carcinoma.
Li Z, Yang W, Qiu J, Xu H, Fan B, Li K, Zhou J, Li Y
Journal of Cancer 2021;12(22):6640-6655
Journal of Cancer 2021;12(22):6640-6655
FGF14-AS2 accelerates tumorigenesis in glioma by forming a feedback loop with miR-320a/E2F1 axis.
Zhang P, Gu X, Zhang N, Liu L, Dong X, Li H, Cheng S, Li S, Yuan J, Li Y, Dong J
Journal of Cancer 2021;12(21):6429-6438
Journal of Cancer 2021;12(21):6429-6438
RUNX1 regulates the proliferation and chemoresistance of colorectal cancer through the Hedgehog signaling pathway.
Li Q, Lai Q, He C, Zhang H, Pan X, Li H, Yan Q, Fang Y, Liu S, Li A
Journal of Cancer 2021;12(21):6363-6371
Journal of Cancer 2021;12(21):6363-6371
Effect of EG00229 on Radiation Resistance of Lung Adenocarcinoma Cells.
Cong L, Yi J, Qiu S, Wang R, Jin S, Jiang R, Cong X
Journal of Cancer 2021;12(20):6105-6117
Journal of Cancer 2021;12(20):6105-6117
miR-552 promotes the proliferation and metastasis of cervical cancer cells through targeting MUC15 pathway.
Zhang X, Zhang Y, Dou L
Journal of Cancer 2021;12(20):6094-6104
Journal of Cancer 2021;12(20):6094-6104
Lipid Storage and Interferon Response Determine the Phenotype of Ground Glass Hepatocytes in Mice and Humans.
Churin Y, Irungbam K, Imiela CS, Schwarz D, Mollenkopf HJ, Drebber U, Odenthal M, Pak O, Huber M, Glebe D, Roderfeld M, Roeb E
Cellular and molecular gastroenterology and hepatology 2021;12(2):383-394
Cellular and molecular gastroenterology and hepatology 2021;12(2):383-394
Co-overexpression of RIOK1 and AKT1 as a prognostic risk factor in glioma.
Wang Y, Xie X, Li S, Zhang D, Zheng H, Zhang M, Zhang Z
Journal of Cancer 2021;12(19):5745-5752
Journal of Cancer 2021;12(19):5745-5752
MRPS17 promotes invasion and metastasis through PI3K/AKT signal pathway and could be potential prognostic marker for gastric cancer.
Zhou W, Ouyang J, Li J, Liu F, An T, Cheng L, Kuo ZC, Zhang C, He Y
Journal of Cancer 2021;12(16):4849-4861
Journal of Cancer 2021;12(16):4849-4861
EIF5A expression and its role as a potential diagnostic biomarker in hepatocellular carcinoma.
Li L, Li X, Zhang Q, Ye T, Zou S, Yan J
Journal of Cancer 2021;12(16):4774-4779
Journal of Cancer 2021;12(16):4774-4779
Demethylzelasteral inhibits proliferation and EMT via repressing Wnt/β-catenin signaling in esophageal squamous cell carcinoma.
Yu J, Wang W, Liu B, Gu J, Chen S, Cui Y, Sun G
Journal of Cancer 2021;12(13):3967-3975
Journal of Cancer 2021;12(13):3967-3975
BCI Suppresses RANKL-Mediated Osteoclastogenesis and Alleviates Ovariectomy-Induced Bone Loss.
Cai C, Hu W, Zhang Y, Hu X, Yang S, Qiu H, Wang R, Ma M, Qiu Y, Chu T
Frontiers in pharmacology 2021;12:772540
Frontiers in pharmacology 2021;12:772540
Histone H2A Nuclear/Cytoplasmic Trafficking Is Essential for Negative Regulation of Antiviral Immune Response and Lysosomal Degradation of TBK1 and IRF3.
Wu XM, Fang H, Zhang J, Bi YH, Chang MX
Frontiers in immunology 2021;12:771277
Frontiers in immunology 2021;12:771277
SOAT1 Promotes Gastric Cancer Lymph Node Metastasis Through Lipid Synthesis.
Zhu T, Wang Z, Zou T, Xu L, Zhang S, Chen Y, Chen C, Zhang W, Wang S, Ding Q, Xu G
Frontiers in pharmacology 2021;12:769647
Frontiers in pharmacology 2021;12:769647
Duhaldea pterocaula (Franch.) Anderb. Attenuates Nociception and Inflammation via GABAA Receptors.
Huang C, Dong C, Zhu Y, Yu Y, Jin H, Zhang Y
Frontiers in pharmacology 2021;12:753128
Frontiers in pharmacology 2021;12:753128
Nox4 Promotes RANKL-Induced Autophagy and Osteoclastogenesis via Activating ROS/PERK/eIF-2α/ATF4 Pathway.
Sun J, Chen W, Li S, Yang S, Zhang Y, Hu X, Qiu H, Wu J, Xu S, Chu T
Frontiers in pharmacology 2021;12:751845
Frontiers in pharmacology 2021;12:751845
Chinese Herbal Preparation SaiLuoTong Alleviates Brain Ischemia via Nrf2 Antioxidation Pathway-Dependent Cerebral Microvascular Protection.
Fan XD, Yao MJ, Yang B, Han X, Zhang YH, Wang GR, Li P, Xu L, Liu JX
Frontiers in pharmacology 2021;12:748568
Frontiers in pharmacology 2021;12:748568
An Integrative Pharmacology Based Analysis of Refined Liuweiwuling Against Liver Injury: A Novel Component Combination and Hepaprotective Mechanism.
Gao Y, Shi W, Yao H, Ai Y, Li R, Wang Z, Liu T, Dai W, Xiao X, Zhao J, Niu M, Bai Z
Frontiers in pharmacology 2021;12:747010
Frontiers in pharmacology 2021;12:747010
Disease-Modifying Anti-rheumatic Drug Prescription Baihu-Guizhi Decoction Attenuates Rheumatoid Arthritis via Suppressing Toll-Like Receptor 4-mediated NLRP3 Inflammasome Activation.
Li W, Mao X, Wang X, Liu Y, Wang K, Li C, Li T, Zhang Y, Lin N
Frontiers in pharmacology 2021;12:743086
Frontiers in pharmacology 2021;12:743086
Remimazolam Protects Against LPS-Induced Endotoxicity Improving Survival of Endotoxemia Mice.
Liu X, Lin S, Zhong Y, Shen J, Zhang X, Luo S, Huang L, Zhang L, Zhou S, Tang J
Frontiers in pharmacology 2021;12:739603
Frontiers in pharmacology 2021;12:739603
Clostridium butyricum Supplement Can Ameliorate the Intestinal Barrier Roles in Broiler Chickens Experimentally Infected With Clostridium perfringens.
Xu X, Yang S, Olajide JS, Qu Z, Gong Z, Wang J, Zhang Y, Wang H, Xiong L, Zhang K, Zhou E, Cai J
Frontiers in physiology 2021;12:737481
Frontiers in physiology 2021;12:737481
Screening of a Small Molecule Compound Library Identifies Toosendanin as an Inhibitor Against Bunyavirus and SARS-CoV-2.
Li S, Ye M, Chen Y, Zhang Y, Li J, Liu W, Li H, Peng K
Frontiers in pharmacology 2021;12:735223
Frontiers in pharmacology 2021;12:735223
Activation of Yes-Associated Protein/PDZ-Binding Motif Pathway Contributes to Endothelial Dysfunction and Vascular Inflammation in AngiotensinII Hypertension.
Xu Q, Zhuo K, Cai R, Su X, Zhang L, Liu Y, Zhu L, Ren F, Zhou MS
Frontiers in physiology 2021;12:732084
Frontiers in physiology 2021;12:732084
Selective STAT3 Inhibitor Alantolactone Ameliorates Osteoarthritis via Regulating Chondrocyte Autophagy and Cartilage Homeostasis.
Pei W, Huang X, Ni B, Zhang R, Niu G, You H
Frontiers in pharmacology 2021;12:730312
Frontiers in pharmacology 2021;12:730312
Fascin-1 is Highly Expressed Specifically in Microglia After Spinal Cord Injury and Regulates Microglial Migration.
Yu S, Cheng L, Tian D, Li Z, Yao F, Luo Y, Liu Y, Zhu Z, Zheng M, Jing J
Frontiers in pharmacology 2021;12:729524
Frontiers in pharmacology 2021;12:729524
VDR Signaling via the Enzyme NAT2 Inhibits Colorectal Cancer Progression.
Zhu C, Wang Z, Cai J, Pan C, Lin S, Zhang Y, Chen Y, Leng M, He C, Zhou P, Wu C, Fang Y, Li Q, Li A, Liu S, Lai Q
Frontiers in pharmacology 2021;12:727704
Frontiers in pharmacology 2021;12:727704
Samotolisib Attenuates Acute Liver Injury Through Inhibiting Caspase-11-Mediated Pyroptosis Via Regulating E3 Ubiquitin Ligase Nedd4.
Zhao YY, Wu DM, He M, Zhang F, Zhang T, Liu T, Li J, Li L, Xu Y
Frontiers in pharmacology 2021;12:726198
Frontiers in pharmacology 2021;12:726198
Huangqi Shengmai Yin Ameliorates Myocardial Fibrosis by Activating Sirtuin3 and Inhibiting TGF-β/Smad Pathway.
Pan J, Cao Z, Fang C, Lei Y, Sun J, Huang X, Han D
Frontiers in pharmacology 2021;12:722530
Frontiers in pharmacology 2021;12:722530
Extracellular CIRP Induces an Inflammatory Phenotype in Pulmonary Fibroblasts via TLR4.
Bolourani S, Sari E, Brenner M, Wang P
Frontiers in immunology 2021;12:721970
Frontiers in immunology 2021;12:721970
ZnT8 Deficiency Protects From APAP-Induced Acute Liver Injury by Reducing Oxidative Stress Through Upregulating Hepatic Zinc and Metallothioneins.
Su W, Feng M, Liu Y, Cao R, Liu Y, Tang J, Pan K, Lan R, Mao Z
Frontiers in pharmacology 2021;12:721471
Frontiers in pharmacology 2021;12:721471
Identification of a Novel Epigenetic Signature CHFR as a Potential Prognostic Gene Involved in Metastatic Clear Cell Renal Cell Carcinoma.
Chen X, Lin J, Chen Q, Liao X, Wang T, Li S, Mao L, Li Z
Frontiers in genetics 2021;12:720979
Frontiers in genetics 2021;12:720979
EGFR-IL-6 Signaling Axis Mediated the Inhibitory Effect of Methylseleninic Acid on Esophageal Squamous Cell Carcinoma.
Wang Y, Liu X, Hu G, Hu C, Gao Y, Huo M, Zhu H, Liu M, Xu N
Frontiers in pharmacology 2021;12:719785
Frontiers in pharmacology 2021;12:719785
Combined Administration of Vitamin D3 and Geniposide Is Less Effective than Single Use of Vitamin D3 or Geniposide in the Treatment of Ulcerative Colitis.
Lu Y, Chen J, He X, Xu S, Chen YE, Gao J, Hou S
Frontiers in pharmacology 2021;12:714065
Frontiers in pharmacology 2021;12:714065
Mefunidone Ameliorates Bleomycin-Induced Pulmonary Fibrosis in Mice.
Han Y, Jiang M, He R, Lv X, Liao X, He Y, Zhang F, Long L, Jiang G, Peng Z, Tao L, Hu G, Meng J
Frontiers in pharmacology 2021;12:713572
Frontiers in pharmacology 2021;12:713572
Sinensetin Reduces Osteoarthritis Pathology in the Tert-Butyl Hydroperoxide-Treated Chondrocytes and the Destabilization of the Medial Meniscus Model Mice via the AMPK/mTOR Signaling Pathway.
Zhou W, Shi Y, Wang H, Yu C, Zhu H, Wu A
Frontiers in pharmacology 2021;12:713491
Frontiers in pharmacology 2021;12:713491
Azithromycin Attenuates Bleomycin-Induced Pulmonary Fibrosis Partly by Inhibiting the Expression of LOX and LOXL-2.
Tong X, Zhang S, Wang D, Zhang L, Huang J, Zhang T, Fan H
Frontiers in pharmacology 2021;12:709819
Frontiers in pharmacology 2021;12:709819
Novel Molecule Nell-1 Promotes the Angiogenic Differentiation of Dental Pulp Stem Cells.
Li M, Wang Q, Han Q, Wu J, Zhu H, Fang Y, Bi X, Chen Y, Yao C, Wang X
Frontiers in physiology 2021;12:703593
Frontiers in physiology 2021;12:703593
Preexposure and Postexposure Prophylaxis of Rabies With Adeno-Associated Virus Expressing Virus-Neutralizing Antibody in Rodent Models.
Huang F, Ren M, Pei J, Mei H, Sui B, Wu Q, Chai B, Yang R, Zhou M, Fu ZF, Zhou H, Zhao L
Frontiers in microbiology 2021;12:702273
Frontiers in microbiology 2021;12:702273
RPL22 Overexpression Promotes Psoriasis-Like Lesion by Inducing Keratinocytes Abnormal Biological Behavior.
Zeng J, Zhang Y, Zhang H, Zhang Y, Gao L, Tong X, Xie Y, Hu Q, Chen C, Ding S, Lu J
Frontiers in immunology 2021;12:699900
Frontiers in immunology 2021;12:699900
Screening and Identification of Key Genes for Activation of Islet Stellate Cell.
Wang X, Carvalho V, Wang Q, Wang J, Li T, Chen Y, Ni C, Liu L, Yuan Y, Qiu S, Sun Z
Frontiers in endocrinology 2021;12:695467
Frontiers in endocrinology 2021;12:695467
Characterization of the Potential Role of NTPCR in Epithelial Ovarian Cancer by Integrating Transcriptomic and Metabolomic Analysis.
Shang H, Zhang H, Ren Z, Zhao H, Zhang Z, Tong J
Frontiers in genetics 2021;12:695245
Frontiers in genetics 2021;12:695245
Preclinical Investigation of Alpinetin in the Treatment of Cancer-Induced Cachexia via Activating PPARγ.
Zhang Y, Zhang Y, Li Y, Zhang L, Yu S
Frontiers in pharmacology 2021;12:687491
Frontiers in pharmacology 2021;12:687491
Overexpression of SHMT2 Predicts a Poor Prognosis and Promotes Tumor Cell Growth in Bladder Cancer.
Zhang P, Yang Q
Frontiers in genetics 2021;12:682856
Frontiers in genetics 2021;12:682856
Loganin Inhibits Angiotensin II-Induced Cardiac Hypertrophy Through the JAK2/STAT3 and NF-κB Signaling Pathways.
Xu JJ, Li RJ, Zhang ZH, Yang C, Liu SX, Li YL, Chen MW, Wang WW, Zhang GY, Song G, Huang ZR
Frontiers in pharmacology 2021;12:678886
Frontiers in pharmacology 2021;12:678886
Traditional Chinese Medication Tongxinluo Attenuates Lipidosis in Ox-LDL-Stimulated Macrophages by Enhancing Beclin-1-Induced Autophagy.
Chen Y, Yu F, Zhang Y, Li M, Di M, Chen W, Liu X, Zhang Y, Zhang M
Frontiers in pharmacology 2021;12:673366
Frontiers in pharmacology 2021;12:673366
SEC23A Is an Independent Prognostic Biomarker in Bladder Cancer Correlated With MAPK Signaling.
Zeng B, Zhao Q, Sun Z, Liu D, Chen H, Li X, Wang J, Xing HR
Frontiers in genetics 2021;12:672832
Frontiers in genetics 2021;12:672832
Pig Liver Esterases Hydrolyze Endocannabinoids and Promote Inflammatory Response.
Zhou Q, Yan B, Sun W, Chen Q, Xiao Q, Xiao Y, Wang X, Shi D
Frontiers in immunology 2021;12:670427
Frontiers in immunology 2021;12:670427
Feasibility and Mechanism Analysis of Shenfu Injection in the Treatment of Idiopathic Pulmonary Fibrosis.
Liu P, Yang S, Wang Z, Dai H, Wang C
Frontiers in pharmacology 2021;12:670146
Frontiers in pharmacology 2021;12:670146
M2a Macrophage-Secreted CHI3L1 Promotes Extracellular Matrix Metabolic Imbalances via Activation of IL-13Rα2/MAPK Pathway in Rat Intervertebral Disc Degeneration.
Li L, Wei K, Ding Y, Ahati P, Xu H, Fang H, Wang H
Frontiers in immunology 2021;12:666361
Frontiers in immunology 2021;12:666361
Atractylodin Attenuates Dextran Sulfate Sodium-Induced Colitis by Alleviating Gut Microbiota Dysbiosis and Inhibiting Inflammatory Response Through the MAPK Pathway.
Qu L, Lin X, Liu C, Ke C, Zhou Z, Xu K, Cao G, Liu Y
Frontiers in pharmacology 2021;12:665376
Frontiers in pharmacology 2021;12:665376
STAT3-Dependent Gene TRIM5γ Interacts With HBx Through a Zinc Binding Site on the BBox Domain.
Song H, Xu F, Pang X, Xiao Q, Wei Q, Lei B, Li X, Fan X, Tan G
Frontiers in microbiology 2021;12:663534
Frontiers in microbiology 2021;12:663534
Lipidomics Revealed Alteration of Sphingolipid Metabolism During the Reparative Phase After Myocardial Infarction Injury.
Hua T, Bao Q, He X, Cai W, He J
Frontiers in physiology 2021;12:663480
Frontiers in physiology 2021;12:663480
SARS-CoV-2 Membrane Protein Inhibits Type I Interferon Production Through Ubiquitin-Mediated Degradation of TBK1.
Sui L, Zhao Y, Wang W, Wu P, Wang Z, Yu Y, Hou Z, Tan G, Liu Q
Frontiers in immunology 2021;12:662989
Frontiers in immunology 2021;12:662989
Targeting Glycogen Synthase Kinase 3 Beta Regulates CD47 Expression After Myocardial Infarction in Rats via the NF-κB Signaling Pathway.
Xu LN, Wang SH, Su XL, Komal S, Fan HK, Xia L, Zhang LR, Han SN
Frontiers in pharmacology 2021;12:662726
Frontiers in pharmacology 2021;12:662726
Characterization of Two Loss-of-Function NF1 Variants in Chinese Patients and Potential Molecular Interpretations of Phenotypes.
Zhang T, Han T, Dong Z, Li C, Lu W
Frontiers in genetics 2021;12:660592
Frontiers in genetics 2021;12:660592
DsbA-L Ameliorates Renal Injury Through the AMPK/NLRP3 Inflammasome Signaling Pathway in Diabetic Nephropathy.
Yang M, Luo S, Jiang N, Wang X, Han Y, Zhao H, Xiong X, Liu Y, Zhao C, Zhu X, Sun L
Frontiers in physiology 2021;12:659751
Frontiers in physiology 2021;12:659751
The New PI3K/mTOR Inhibitor GNE-477 Inhibits the Malignant Behavior of Human Glioblastoma Cells.
Wang Y, Shen H, Sun Q, Zhao L, Liu H, Ye L, Xu Y, Cai J, Li Y, Gao L, Tan Y, Liu B, Chen Q
Frontiers in pharmacology 2021;12:659511
Frontiers in pharmacology 2021;12:659511
Effect of Protein O-Mannosyltransferase (MSMEG_5447) on M. smegmatis and Its Survival in Macrophages.
Jia L, Sha S, Yang S, Taj A, Ma Y
Frontiers in microbiology 2021;12:657726
Frontiers in microbiology 2021;12:657726
Pulmonary Artery Smooth Muscle Cell Senescence Promotes the Proliferation of PASMCs by Paracrine IL-6 in Hypoxia-Induced Pulmonary Hypertension.
Wang AP, Yang F, Tian Y, Su JH, Gu Q, Chen W, Gong SX, Ma XF, Qin XP, Jiang ZS
Frontiers in physiology 2021;12:656139
Frontiers in physiology 2021;12:656139
SARS-CoV-2 Accessory Protein ORF7b Mediates Tumor Necrosis Factor-α-Induced Apoptosis in Cells.
Yang R, Zhao Q, Rao J, Zeng F, Yuan S, Ji M, Sun X, Li J, Yang J, Cui J, Jin Z, Liu L, Liu Z
Frontiers in microbiology 2021;12:654709
Frontiers in microbiology 2021;12:654709
Interferon-Lambda 1 Inhibits Staphylococcus aureus Colonization in Human Primary Keratinocytes.
Wu X, Zhao Y, Gu Y, Li K, Wang X, Zhang J
Frontiers in pharmacology 2021;12:652302
Frontiers in pharmacology 2021;12:652302
The Treatment of Rhodiola Mimics Exercise to Resist High-Fat Diet-Induced Muscle Dysfunction via Sirtuin1-Dependent Mechanisms.
You B, Dun Y, Fu S, Qi D, Zhang W, Liu Y, Qiu L, Xie M, Liu S
Frontiers in pharmacology 2021;12:646489
Frontiers in pharmacology 2021;12:646489
Anti-Hyperuricemic and Nephroprotective Effects of Dihydroberberine in Potassium Oxonate- and Hypoxanthine-Induced Hyperuricemic Mice.
Xu L, Lin G, Yu Q, Li Q, Mai L, Cheng J, Xie J, Liu Y, Su Z, Li Y
Frontiers in pharmacology 2021;12:645879
Frontiers in pharmacology 2021;12:645879
Bellidifolin Ameliorates Isoprenaline-Induced Myocardial Fibrosis by Regulating TGF-β1/Smads and p38 Signaling and Preventing NR4A1 Cytoplasmic Localization.
Yang HX, Sun JH, Yao TT, Li Y, Xu GR, Zhang C, Liu XC, Zhou WW, Song QH, Zhang Y, Li AY
Frontiers in pharmacology 2021;12:644886
Frontiers in pharmacology 2021;12:644886
Berberine Attenuates Chronic Atrophic Gastritis Induced by MNNG and Its Potential Mechanism.
Tong Y, Liu L, Wang R, Yang T, Wen J, Wei S, Jing M, Zou W, Zhao Y
Frontiers in pharmacology 2021;12:644638
Frontiers in pharmacology 2021;12:644638
Effects of Allicin on Late Sodium Current Caused by ΔKPQ-SCN5A Mutation in HEK293 Cells.
Chen Y, Huang Y, Bai J, Liu C, Ma S, Li J, Lu X, Fu Z, Fang L, Li Y, Zhang J
Frontiers in physiology 2021;12:636485
Frontiers in physiology 2021;12:636485
The Crucial Role of PPARγ-Egr-1-Pro-Inflammatory Mediators Axis in IgG Immune Complex-Induced Acute Lung Injury.
Yan C, Chen J, Ding Y, Zhou Z, Li B, Deng C, Yuan D, Zhang Q, Wang X
Frontiers in immunology 2021;12:634889
Frontiers in immunology 2021;12:634889
Repurposing of Pirfenidone (Anti-Pulmonary Fibrosis Drug) for Treatment of Rheumatoid Arthritis.
Gan D, Cheng W, Ke L, Sun AR, Jia Q, Chen J, Lin J, Li J, Xu Z, Zhang P
Frontiers in pharmacology 2021;12:631891
Frontiers in pharmacology 2021;12:631891
Jian-Pi-Yi-Shen Formula Ameliorates Oxidative Stress, Inflammation, and Apoptosis by Activating the Nrf2 Signaling in 5/6 Nephrectomized Rats.
Zhou F, Zou X, Zhang J, Wang Z, Yang Y, Wang D
Frontiers in pharmacology 2021;12:630210
Frontiers in pharmacology 2021;12:630210
Sinomenine Attenuated Capsaicin-Induced Increase in Cough Sensitivity in Guinea Pigs by Inhibiting SOX5/TRPV1 Axis and Inflammatory Response.
Ma JL, Ji K, Shi LQ, Li NN, Wang LY, Dong SJ, Zhang YX, Wen SH, Liu XM, Wang Y, Luo JY
Frontiers in physiology 2021;12:629276
Frontiers in physiology 2021;12:629276
Remdesivir Inhibits Tubulointerstitial Fibrosis in Obstructed Kidneys.
Xu L, Tan B, Huang D, Yuan M, Li T, Wu M, Ye C
Frontiers in pharmacology 2021;12:626510
Frontiers in pharmacology 2021;12:626510
Compound Dihuang Granule Inhibits Nigrostriatal Pathway Apoptosis in Parkinson's Disease by Suppressing the JNK/AP-1 Pathway.
Wang L, Yang YF, Chen L, He ZQ, Bi DY, Zhang L, Xu YW, He JC
Frontiers in pharmacology 2021;12:621359
Frontiers in pharmacology 2021;12:621359
MicroRNA-497 Reduction and Increase of Its Family Member MicroRNA-424 Lead to Dysregulation of Multiple Inflammation Related Genes in Synovial Fibroblasts With Rheumatoid Arthritis.
Wang S, Xu J, Guo Y, Cai Y, Ren X, Zhu W, Geng M, Meng L, Jiang C, Lu S
Frontiers in immunology 2021;12:619392
Frontiers in immunology 2021;12:619392
Hepatitis B Surface Antigen Suppresses the Activation of Nuclear Factor Kappa B Pathway via Interaction With the TAK1-TAB2 Complex.
Deng F, Xu G, Cheng Z, Huang Y, Ma C, Luo C, Yu C, Wang J, Xu X, Liu S, Zhu Y
Frontiers in immunology 2021;12:618196
Frontiers in immunology 2021;12:618196
Quercitrin Attenuates Acetaminophen-Induced Acute Liver Injury by Maintaining Mitochondrial Complex I Activity.
Xiong W, Yuan Z, Wang T, Wu S, Xiong Y, Yao Y, Yang Y, Wu H
Frontiers in pharmacology 2021;12:586010
Frontiers in pharmacology 2021;12:586010
PRMT5 functionally associates with EZH2 to promote colorectal cancer progression through epigenetically repressing CDKN2B expression.
Yang L, Ma DW, Cao YP, Li DZ, Zhou X, Feng JF, Bao J
Theranostics 2021;11(8):3742-3759
Theranostics 2021;11(8):3742-3759
Inhibition of BAG3 enhances the anticancer effect of shikonin in hepatocellular carcinoma.
Lu J, Liu SY, Zhang J, Yang GM, Gao GB, Yu NN, Li YP, Li YX, Ma ZQ, Wang Y, Lu CH
American journal of cancer research 2021;11(7):3575-3593
American journal of cancer research 2021;11(7):3575-3593
Honokiol induces ferroptosis in colon cancer cells by regulating GPX4 activity.
Guo C, Liu P, Deng G, Han Y, Chen Y, Cai C, Shen H, Deng G, Zeng S
American journal of cancer research 2021;11(6):3039-3054
American journal of cancer research 2021;11(6):3039-3054
NONO phase separation enhances DNA damage repair by accelerating nuclear EGFR-induced DNA-PK activation.
Fan XJ, Wang YL, Zhao WW, Bai SM, Ma Y, Yin XK, Feng LL, Feng WX, Wang YN, Liu Q, Hung MC, Wan XB
American journal of cancer research 2021;11(6):2838-2852
American journal of cancer research 2021;11(6):2838-2852
Platelet-derived microvesicles induce calcium oscillations and promote VSMC migration via TRPV4.
Li SS, Gao S, Chen Y, Bao H, Li ZT, Yao QP, Liu JT, Wang Y, Qi YX
Theranostics 2021;11(5):2410-2423
Theranostics 2021;11(5):2410-2423
Glycosylation of Siglec15 promotes immunoescape and tumor growth.
Wang YL, Wei MB, Zhao WW, Feng LL, Yin XK, Bai SM, Wan XB, Hung MC, Zou AZ, Wang MH, Zheng J, Qin C, Fan XJ
American journal of cancer research 2021;11(5):2291-2302
American journal of cancer research 2021;11(5):2291-2302
YY1-mediated reticulocalbin-2 upregulation promotes the hepatocellular carcinoma progression via activating MYC signaling.
Mei C, Jiang X, Gu Y, Wu X, Ma W, Chen X, Wang G, Yao Y, Liu Y, Zhang Z, Yuan Y
American journal of cancer research 2021;11(5):2238-2251
American journal of cancer research 2021;11(5):2238-2251
TSL-1502, a glucuronide prodrug of a poly (ADP-ribose) polymerase (PARP) inhibitor, exhibits potent anti-tumor activity in preclinical models.
Wang L, Zhu X, Li L, Li L, Fu L, Li Y, Fu H, Chen X, Lou L
American journal of cancer research 2021;11(4):1632-1645
American journal of cancer research 2021;11(4):1632-1645
TM2D1 contributes the epithelial-mesenchymal transition of hepatocellular carcinoma via modulating AKT/β-catenin axis.
Hu JW, Yin Y, Gao Y, Nie YY, Fu PY, Cai JB, Zhu K, Huang C, Huang XW, Yang XR, Cao Y, Qiu SJ, Fan J, Zhou J
American journal of cancer research 2021;11(4):1557-1571
American journal of cancer research 2021;11(4):1557-1571
A Mitochondrial DNA Variant Elevates the Risk of Gallstone Disease by Altering Mitochondrial Function.
Sun D, Niu Z, Zheng HX, Wu F, Jiang L, Han TQ, Wei Y, Wang J, Jin L
Cellular and molecular gastroenterology and hepatology 2021;11(4):1211-1226.e15
Cellular and molecular gastroenterology and hepatology 2021;11(4):1211-1226.e15
Loss of BRMS2 induces cell growth inhibition and translation capacity reduction in colorectal cancer cells.
Liu Y, Xu W, Xu X, Tan Z, Xu J, Ma L, Du P, Yang Y
American journal of cancer research 2021;11(3):930-944
American journal of cancer research 2021;11(3):930-944
S100A11 Promotes Liver Steatosis via FOXO1-Mediated Autophagy and Lipogenesis.
Zhang L, Zhang Z, Li C, Zhu T, Gao J, Zhou H, Zheng Y, Chang Q, Wang M, Wu J, Ran L, Wu Y, Miao H, Zou X, Liang B
Cellular and molecular gastroenterology and hepatology 2021;11(3):697-724
Cellular and molecular gastroenterology and hepatology 2021;11(3):697-724
Exosome-mediated delivery of inflammation-responsive Il-10 mRNA for controlled atherosclerosis treatment.
Bu T, Li Z, Hou Y, Sun W, Zhang R, Zhao L, Wei M, Yang G, Yuan L
Theranostics 2021;11(20):9988-10000
Theranostics 2021;11(20):9988-10000
Rapid design and development of CRISPR-Cas13a targeting SARS-CoV-2 spike protein.
Wang L, Zhou J, Wang Q, Wang Y, Kang C
Theranostics 2021;11(2):649-664
Theranostics 2021;11(2):649-664
Designer exosomes for targeted and efficient ferroptosis induction in cancer via chemo-photodynamic therapy.
Du J, Wan Z, Wang C, Lu F, Wei M, Wang D, Hao Q
Theranostics 2021;11(17):8185-8196
Theranostics 2021;11(17):8185-8196
TRPV2-spike protein interaction mediates the entry of SARS-CoV-2 into macrophages in febrile conditions.
Xu J, Yang Y, Hou Z, Jia H, Wang Y
Theranostics 2021;11(15):7379-7390
Theranostics 2021;11(15):7379-7390
Nanoparticle encapsulation of non-genotoxic p53 activator Inauhzin-C for improved therapeutic efficacy.
Bhattarai N, Wang J, Nguyen D, Yang X, Helmers L, Paruch J, Li L, Zhang Y, Meng K, Wang A, Jayawickramarajah J, Wang B, Zeng S, Lu H
Theranostics 2021;11(14):7005-7017
Theranostics 2021;11(14):7005-7017
KAT6A, a novel regulator of β-catenin, promotes tumorigenicity and chemoresistance in ovarian cancer by acetylating COP1.
Liu W, Zhan Z, Zhang M, Sun B, Shi Q, Luo F, Zhang M, Zhang W, Hou Y, Xiao X, Li Y, Feng H
Theranostics 2021;11(13):6278-6292
Theranostics 2021;11(13):6278-6292
Relieving lipid accumulation through UCP1 suppresses the progression of acute kidney injury by promoting the AMPK/ULK1/autophagy pathway.
Xiong W, Xiong Z, Song A, Lei C, Ye C, Zhang C
Theranostics 2021;11(10):4637-4654
Theranostics 2021;11(10):4637-4654
Cardiac telocytes inhibit cardiac microvascular endothelial cell apoptosis through exosomal miRNA-21-5p-targeted cdip1 silencing to improve angiogenesis following myocardial infarction.
Liao Z, Chen Y, Duan C, Zhu K, Huang R, Zhao H, Hintze M, Pu Q, Yuan Z, Lv L, Chen H, Lai B, Feng S, Qi X, Cai D
Theranostics 2021;11(1):268-291
Theranostics 2021;11(1):268-291
The Circ_0001367/miR-545-3p/LUZP1 Axis Regulates Cell Proliferation, Migration and Invasion in Glioma Cells.
Dong X, Zhang P, Liu L, Li H, Cheng S, Li S, Wang Y, Zheng C, Dong J, Zhang L
Frontiers in oncology 2021;11:781471
Frontiers in oncology 2021;11:781471
A Class of Protein-Coding RNAs Binds to Polycomb Repressive Complex 2 and Alters Histone Methylation.
Liao M, Sun X, Gao S, Zhang Y
Frontiers in oncology 2021;11:739830
Frontiers in oncology 2021;11:739830
DEAD-Box Helicase DDX6 Facilitated RIG-I-Mediated Type-I Interferon Response to EV71 Infection.
Zhang R, Cheng M, Liu B, Yuan M, Chen D, Wang Y, Wu Z
Frontiers in cellular and infection microbiology 2021;11:725392
Frontiers in cellular and infection microbiology 2021;11:725392
TFCP2 Overcomes Senescence by Cooperating With SREBP2 to Activate Cholesterol Synthesis in Pancreatic Cancer.
Zhang D, Lu P, Zhu K, Wu H, Dai Y
Frontiers in oncology 2021;11:724437
Frontiers in oncology 2021;11:724437
LncRNA LGALS8-AS1 Promotes Breast Cancer Metastasis Through miR-125b-5p/SOX12 Feedback Regulatory Network.
Zhai D, Li T, Ye R, Bi J, Kuang X, Shi Y, Shao N, Lin Y
Frontiers in oncology 2021;11:711684
Frontiers in oncology 2021;11:711684
Siglec-15 Promotes Tumor Progression in Osteosarcoma via DUSP1/MAPK Pathway.
Fan MK, Zhang GC, Chen W, Qi LL, Xie MF, Zhang YY, Wang L, Zhang Q
Frontiers in oncology 2021;11:710689
Frontiers in oncology 2021;11:710689
METTL3 Promotes the Resistance of Glioma to Temozolomide via Increasing MGMT and ANPG in a m6A Dependent Manner.
Shi J, Chen G, Dong X, Li H, Li S, Cheng S, Li Y, Wang L, Yuan J, Qian Z, Dong J
Frontiers in oncology 2021;11:702983
Frontiers in oncology 2021;11:702983
SPNS2 Downregulation Induces EMT and Promotes Colorectal Cancer Metastasis via Activating AKT Signaling Pathway.
Lv L, Yi Q, Yan Y, Chao F, Li M
Frontiers in oncology 2021;11:682773
Frontiers in oncology 2021;11:682773
TIPE2 Suppresses Malignancy of Pancreatic Cancer Through Inhibiting TGFβ1 Mediated Signaling Pathway.
Feng F, Liu C, Bian H, Cai W, Zhou Y, Zhou L, Zhuang Z
Frontiers in oncology 2021;11:680985
Frontiers in oncology 2021;11:680985
Downregulation of miR-135b-5p Suppresses Progression of Esophageal Cancer and Contributes to the Effect of Cisplatin.
Di Y, Jiang Y, Shen X, Liu J, Gao Y, Cai H, Sun X, Ning D, Liu B, Lei J, Jin S
Frontiers in oncology 2021;11:679348
Frontiers in oncology 2021;11:679348
miR-1258 Attenuates Tumorigenesis Through Targeting E2F1 to Inhibit PCNA and MMP2 Transcription in Glioblastoma.
Qin H, Gui Y, Ma R, Zhang H, Guo Y, Ye Y, Li J, Zhao L, Wang Y
Frontiers in oncology 2021;11:671144
Frontiers in oncology 2021;11:671144
The Deubiquitinase USP39 Promotes ESCC Tumorigenesis Through Pre-mRNA Splicing of the mTORC2 Component Rictor.
Zhao Y, Geng H, Liu G, Ji Q, Cheng X, Li X, Liu W, Thorne RF, Zhang R, Liu X
Frontiers in oncology 2021;11:667495
Frontiers in oncology 2021;11:667495
Pinocembrin Inhibits the Proliferation and Metastasis of Breast Cancer via Suppression of the PI3K/AKT Signaling Pathway.
Zhu X, Li R, Wang C, Zhou S, Fan Y, Ma S, Gao D, Gai N, Yang J
Frontiers in oncology 2021;11:661184
Frontiers in oncology 2021;11:661184
N2E4, a Monoclonal Antibody Targeting Neuropilin-2, Inhibits Tumor Growth and Metastasis in Pancreatic Ductal Adenocarcinoma via Suppressing FAK/Erk/HIF-1α Signaling.
Wang L, Wang L, Wang S, Zhou Z, Liu Z, Xu P, Luo X, Wu T, Luo F, Yan J
Frontiers in oncology 2021;11:657008
Frontiers in oncology 2021;11:657008
Analysis of Long Noncoding RNAs in Aila-Induced Non-Small Cell Lung Cancer Inhibition.
Chen L, Wu C, Wang H, Chen S, Ma D, Tao Y, Wang X, Luan Y, Wang T, Shi Y, Song G, Zhao Y, Dong X, Wang B
Frontiers in oncology 2021;11:652567
Frontiers in oncology 2021;11:652567
MiR-489-3p Reduced Pancreatic Cancer Proliferation and Metastasis By Targeting PKM2 and LDHA Involving Glycolysis.
Zhang D, He Z, Shen Y, Wang J, Liu T, Jiang J
Frontiers in oncology 2021;11:651535
Frontiers in oncology 2021;11:651535
SLC1A4: A Powerful Prognostic Marker and Promising Therapeutic Target for HCC.
Peng X, Chen R, Cai S, Lu S, Zhang Y
Frontiers in oncology 2021;11:650355
Frontiers in oncology 2021;11:650355
LncRNA SNHG8 Promotes Proliferation and Inhibits Apoptosis of Diffuse Large B-Cell Lymphoma via Sponging miR-335-5p.
Yu B, Wang B, Wu Z, Wu C, Ling J, Gao X, Zeng H
Frontiers in oncology 2021;11:650287
Frontiers in oncology 2021;11:650287
Long Noncoding RNA SNHG12 Promotes Gastric Cancer Proliferation by Binding to HuR and Stabilizing YWHAZ Expression Through the AKT/GSK-3β Pathway.
Zhang T, Beeharry MK, Zheng Y, Wang Z, Li J, Zhu Z, Li C
Frontiers in oncology 2021;11:645832
Frontiers in oncology 2021;11:645832
The Overexpression of Acyl-CoA Medium-Chain Synthetase-3 (ACSM3) Suppresses the Ovarian Cancer Progression via the Inhibition of Integrin β1/AKT Signaling Pathway.
Yan L, He Z, Li W, Liu N, Gao S
Frontiers in oncology 2021;11:644840
Frontiers in oncology 2021;11:644840
TFEB Promotes Prostate Cancer Progression via Regulating ABCA2-Dependent Lysosomal Biogenesis.
Zhu X, Zhuo Y, Wu S, Chen Y, Ye J, Deng Y, Feng Y, Liu R, Cai S, Zou Z, Wang B, Wu CL, Zeng G, Zhong W
Frontiers in oncology 2021;11:632524
Frontiers in oncology 2021;11:632524
DDX19A Promotes Metastasis of Cervical Squamous Cell Carcinoma by Inducing NOX1-Mediated ROS Production.
Jiang Y, Wang B, Li Y, Shen J, Wei Y, Li H, Chen S, Yang H, Zeng F, Liu C, Wang F, He H, Chen Y, Liu J
Frontiers in oncology 2021;11:629974
Frontiers in oncology 2021;11:629974
circATP2B1 Promotes Aerobic Glycolysis in Gastric Cancer Cells Through Regulation of the miR-326 Gene Cluster.
Zhao X, Tian Z, Liu L
Frontiers in oncology 2021;11:628624
Frontiers in oncology 2021;11:628624
Overexpressed Tumor Suppressor Exosomal miR-15a-5p in Cancer Cells Inhibits PD1 Expression in CD8+T Cells and Suppresses the Hepatocellular Carcinoma Progression.
Zhang HY, Liang HX, Wu SH, Jiang HQ, Wang Q, Yu ZJ
Frontiers in oncology 2021;11:622263
Frontiers in oncology 2021;11:622263
Identification and Confirmation of the miR-30 Family as a Potential Central Player in Tobacco-Related Head and Neck Squamous Cell Carcinoma.
Zhang T, Zhu X, Sun Q, Qin X, Zhang Z, Feng Y, Yan M, Chen W
Frontiers in oncology 2021;11:616372
Frontiers in oncology 2021;11:616372
miR-4461 Regulates the Proliferation and Metastasis of Ovarian Cancer Cells and Cisplatin Resistance.
Dou L, Zhang Y
Frontiers in oncology 2021;11:614035
Frontiers in oncology 2021;11:614035
miR-139-5p Loss-Mediated WTAP Activation Contributes to Hepatocellular Carcinoma Progression by Promoting the Epithelial to Mesenchymal Transition.
Liu W, Gao X, Chen X, Zhao N, Sun Y, Zou Y, Guan Y, Yang L, Pei X, Wang G, Wang B, Li M, Song W
Frontiers in oncology 2021;11:611544
Frontiers in oncology 2021;11:611544
PSMC2 Regulates Cell Cycle Progression Through the p21/Cyclin D1 Pathway and Predicts a Poor Prognosis in Human Hepatocellular Carcinoma.
Liu Y, Chen H, Li X, Zhang F, Kong L, Wang X, Bai J, Wu X
Frontiers in oncology 2021;11:607021
Frontiers in oncology 2021;11:607021
The Role of Tim-3 on dNK Cells Dysfunction During Abnormal Pregnancy With Toxoplasma gondii Infection.
Li T, Cui L, Xu X, Zhang H, Jiang Y, Ren L, Yang C, Liu X, Hu X
Frontiers in cellular and infection microbiology 2021;11:587150
Frontiers in cellular and infection microbiology 2021;11:587150
Bispecific c-Met/PD-L1 CAR-T Cells Have Enhanced Therapeutic Effects on Hepatocellular Carcinoma.
Jiang W, Li T, Guo J, Wang J, Jia L, Shi X, Yang T, Jiao R, Wei X, Feng Z, Tang Q, Ji G
Frontiers in oncology 2021;11:546586
Frontiers in oncology 2021;11:546586
Schisandrin Restores the Amyloid β-Induced Impairments on Mitochondrial Function, Energy Metabolism, Biogenesis, and Dynamics in Rat Primary Hippocampal Neurons.
Piao Z, Song L, Yao L, Zhang L, Lu Y
Pharmacology 2021;106(5-6):254-264
Pharmacology 2021;106(5-6):254-264
Preliminary therapeutic and mechanistic evaluation of S-allylmercapto-N-acetylcysteine in the treatment of pulmonary emphysema.
Zheng D, Wang J, Li G, Sun Y, Deng Q, Li M, Song K, Zhao Z
International immunopharmacology 2021 Sep;98:107913
International immunopharmacology 2021 Sep;98:107913
Protective effect and mechanism of nicotinamide adenine dinucleotide against optic neuritis in mice with experimental autoimmune encephalomyelitis.
Guo J, Li B, Wang J, Guo R, Tian Y, Song S, Guo L
International immunopharmacology 2021 Sep;98:107846
International immunopharmacology 2021 Sep;98:107846
ITPRIP promotes glioma progression by linking MYL9 to DAPK1 inhibition.
Cao C, He K, Li S, Ge Q, Liu L, Zhang Z, Zhang H, Wang X, Sun X, Ding L
Cellular signalling 2021 Sep;85:110062
Cellular signalling 2021 Sep;85:110062
CPEB1 enhances erastin-induced ferroptosis in gastric cancer cells by suppressing twist1 expression.
Wang J, Wang T, Zhang Y, Liu J, Song J, Han Y, Wang L, Yang S, Zhu L, Geng R, Li W, Yu X
IUBMB life 2021 Sep;73(9):1180-1190
IUBMB life 2021 Sep;73(9):1180-1190
ZMPSTE24 Regulates SARS-CoV-2 Spike Protein-enhanced Expression of Endothelial PAI-1.
Han M, Pandey D
American journal of respiratory cell and molecular biology 2021 Sep;65(3):300-308
American journal of respiratory cell and molecular biology 2021 Sep;65(3):300-308
MiR-499a prevents astrocytes mediated inflammation in ischemic stroke by targeting PTEN.
Guan X, Zhang Y, Gareev I, Beylerli O, Li X, Lu G, Lv L, Hai X
Non-coding RNA research 2021 Sep;6(3):146-152
Non-coding RNA research 2021 Sep;6(3):146-152
Riluzole does not ameliorate disease caused by cytoplasmic TDP-43 in a mouse model of amyotrophic lateral sclerosis.
Wright AL, Della Gatta PA, Le S, Berning BA, Mehta P, Jacobs KR, Gul H, San Gil R, Hedl TJ, Riddell WR, Watson O, Keating SS, Venturato J, Chung RS, Atkin JD, Lee A, Shi B, Blizzard CA, Morsch M, Walker AK
The European journal of neuroscience 2021 Sep;54(6):6237-6255
The European journal of neuroscience 2021 Sep;54(6):6237-6255
TAZ as a novel regulator of oxidative damage in decidualization via Nrf2/ARE/Foxo1 pathway.
Yu HF, Zheng LW, Yang ZQ, Wang YS, Wang TT, Yue ZP, Guo B
Experimental & molecular medicine 2021 Sep;53(9):1307-1318
Experimental & molecular medicine 2021 Sep;53(9):1307-1318
Activation of Transient Receptor Potential Ankyrin 1 and Vanilloid 1 Channels Promotes Odontogenic Differentiation of Human Dental Pulp Cells.
Lou Y, Liu Y, Zhao J, Tian W, Xu N, Zang C, Que K
Journal of endodontics 2021 Sep;47(9):1409-1416
Journal of endodontics 2021 Sep;47(9):1409-1416
Identifying miRNA modules associated with progression of keloids through weighted gene co-expression network analysis and experimental validation in vitro.
Lv W, Ren Y, Wu M, Luo X, Yu J, Zhang Q, Wu Y
Burns : journal of the International Society for Burn Injuries 2021 Sep;47(6):1359-1372
Burns : journal of the International Society for Burn Injuries 2021 Sep;47(6):1359-1372
miR-138 inhibits epithelial-mesenchymal transition in silica-induced pulmonary fibrosis by regulating ZEB2.
Wu Q, Gui W, Jiao B, Han L, Wang F
Toxicology 2021 Sep;461:152925
Toxicology 2021 Sep;461:152925
miRNA‑7515 suppresses pancreatic cancer cell proliferation, migration and invasion via downregulating IGF‑1 expression.
Lei S, Zeng Z, He Z, Cao W
Oncology reports 2021 Sep;46(3)
Oncology reports 2021 Sep;46(3)
Chronic stress promotes glioma cell proliferation via the PI3K/Akt signaling pathway.
Zhang ZQ, Wang X, Xue BH, Zhao Y, Xie F, Wang SD, Xue C, Wang Y, Zhang YS, Qian LJ
Oncology reports 2021 Sep;46(3)
Oncology reports 2021 Sep;46(3)
MicroRNA-214 contributes to Ang II-induced cardiac hypertrophy by targeting SIRT3 to provoke mitochondrial malfunction.
Ding YQ, Zhang YH, Lu J, Li B, Yu WJ, Yue ZB, Hu YH, Wang PX, Li JY, Cai SD, Ye JT, Liu PQ
Acta pharmacologica Sinica 2021 Sep;42(9):1422-1436
Acta pharmacologica Sinica 2021 Sep;42(9):1422-1436
Genetically encoded FRET fluorescent sensor designed for detecting MOF histone acetyltransferase activity in vitro and in living cells.
Han Q, Chen F, Liu S, Ge Y, Wu J, Liu D
Analytical and bioanalytical chemistry 2021 Sep;413(21):5453-5461
Analytical and bioanalytical chemistry 2021 Sep;413(21):5453-5461
The scaffold protein IQGAP1 links heat-induced stress signals to alternative splicing regulation in gastric cancer cells.
Birladeanu AM, Rogalska M, Potiri M, Papadaki V, Andreadou M, Kontoyiannis DL, Lewis JD, Erpapazoglou Z, Kafasla P
Oncogene 2021 Sep;40(36):5518-5532
Oncogene 2021 Sep;40(36):5518-5532
miR-351-3p promotes rat amniotic fluid-derived mesenchymal stromal cell proliferation via targeting the coding sequence of Abca4.
Huang J, Zhao Q, Wei X, Ma W, Luo W, Gu H, Liu D, He Y, Huang T, Liu Y, Wang C, Yuan Z
Stem cells (Dayton, Ohio) 2021 Sep;39(9):1192-1206
Stem cells (Dayton, Ohio) 2021 Sep;39(9):1192-1206
FSH modulated cartilage ECM metabolism by targeting the PKA/CREB/SOX9 pathway.
Zhang M, Wang Y, Huan Z, Liu Y, Zhang W, Kong D, Kong L, Xu J
Journal of bone and mineral metabolism 2021 Sep;39(5):769-779
Journal of bone and mineral metabolism 2021 Sep;39(5):769-779
miRNA-10a-5p inhibits cell metastasis in hepatocellular carcinoma via targeting SKA1.
Shen D, Zhao HY, Gu AD, Wu YW, Weng YH, Li SJ, Song JY, Gu XF, Qiu J, Zhao W
The Kaohsiung journal of medical sciences 2021 Sep;37(9):784-794
The Kaohsiung journal of medical sciences 2021 Sep;37(9):784-794
Triclosan regulates the Nrf2/HO-1 pathway through the PI3K/Akt/JNK signaling cascade to induce oxidative damage in neurons.
Wang D, Liu J, Jiang H
Environmental toxicology 2021 Sep;36(9):1953-1964
Environmental toxicology 2021 Sep;36(9):1953-1964
TRIP13 exerts a cancer-promoting role in cervical cancer by enhancing Wnt/β-catenin signaling via ACTN4.
Liu X, Shen X, Zhang J
Environmental toxicology 2021 Sep;36(9):1829-1840
Environmental toxicology 2021 Sep;36(9):1829-1840
Hsp70 chaperones TDP-43 in dynamic, liquid-like phase and prevents it from amyloid aggregation.
Gu J, Wang C, Hu R, Li Y, Zhang S, Sun Y, Wang Q, Li D, Fang Y, Liu C
Cell research 2021 Sep;31(9):1024-1027
Cell research 2021 Sep;31(9):1024-1027
The deubiquitinase USP10 restores PTEN activity and inhibits non-small cell lung cancer cell proliferation.
He Y, Jiang S, Mao C, Zheng H, Cao B, Zhang Z, Zhao J, Zeng Y, Mao X
The Journal of biological chemistry 2021 Sep;297(3):101088
The Journal of biological chemistry 2021 Sep;297(3):101088
AMPK phosphorylates PPARδ to mediate its stabilization, inhibit glucose and glutamine uptake and colon tumor growth.
Ding J, Gou Q, Jia X, Liu Q, Jin J, Shi J, Hou Y
The Journal of biological chemistry 2021 Sep;297(3):100954
The Journal of biological chemistry 2021 Sep;297(3):100954
The inhibitory effect of the deubiquitinase cylindromatosis (CYLD) on inflammatory responses in human gingival fibroblasts.
Fu YW, Li L, Wang XQ, Zhou Y, Zhu LF, Mei YM, Xu Y
Oral diseases 2021 Sep;27(6):1487-1497
Oral diseases 2021 Sep;27(6):1487-1497
Human forebrain endothelial cell therapy for psychiatric disorders.
Datta D, Subburaju S, Kaye S, Baruah J, Choi YK, Nian Y, Khalili JS, Chung S, Elkhal A, Vasudevan A
Molecular psychiatry 2021 Sep;26(9):4864-4883
Molecular psychiatry 2021 Sep;26(9):4864-4883
N-3 polyunsaturated fatty acids promote astrocyte differentiation and neurotrophin production independent of cAMP in patient-derived neural stem cells.
Yu JZ, Wang J, Sheridan SD, Perlis RH, Rasenick MM
Molecular psychiatry 2021 Sep;26(9):4605-4615
Molecular psychiatry 2021 Sep;26(9):4605-4615
DNM3OS regulates GAPDH expression and influences the molecular pathogenesis of Huntington's disease.
Dong X, Cong S
Journal of cellular and molecular medicine 2021 Sep;25(18):9066-9071
Journal of cellular and molecular medicine 2021 Sep;25(18):9066-9071
The effects of NCBP3 on METTL3-mediated m6A RNA methylation to enhance translation process in hypoxic cardiomyocytes.
Ye F, Wang X, Tu S, Zeng L, Deng X, Luo W, Zhang Z
Journal of cellular and molecular medicine 2021 Sep;25(18):8920-8928
Journal of cellular and molecular medicine 2021 Sep;25(18):8920-8928
Effects of different intensities of continuous training on vascular inflammation and oxidative stress in spontaneously hypertensive rats.
Luo M, Cao C, Niebauer J, Yan J, Ma X, Chang Q, Zhang T, Huang X, Liu G
Journal of cellular and molecular medicine 2021 Sep;25(17):8522-8536
Journal of cellular and molecular medicine 2021 Sep;25(17):8522-8536
Abdominal paracentesis drainage attenuates intestinal mucosal barrier damage through macrophage polarization in severe acute pancreatitis.
Yuan X, Luo C, Wu J, Li W, Guo X, Li S, Wang B, Sun H, Tang L
Experimental biology and medicine (Maywood, N.J.) 2021 Sep;246(18):2029-2038
Experimental biology and medicine (Maywood, N.J.) 2021 Sep;246(18):2029-2038
miR‑140‑5p alleviates mouse liver ischemia/reperfusion injury by targeting CAPN1.
Yu Q, Chen S, Tang H, Yang H, Zhang J, Shi X, Li J, Guo W, Zhang S
Molecular medicine reports 2021 Sep;24(3)
Molecular medicine reports 2021 Sep;24(3)
Endoglin deficiency impairs VEGFR2 but not FGFR1 or TIE2 activation and alters VEGF-mediated cellular responses in human primary endothelial cells.
Zhang Q, Wang C, Cannavicci A, Faughnan ME, Kutryk MJB
Translational research : the journal of laboratory and clinical medicine 2021 Sep;235:129-143
Translational research : the journal of laboratory and clinical medicine 2021 Sep;235:129-143
PDIA6 promotes pancreatic cancer progression and immune escape through CSN5-mediated deubiquitination of β-catenin and PD-L1.
Ma Y, Xia P, Wang Z, Xu J, Zhang L, Jiang Y
Neoplasia (New York, N.Y.) 2021 Sep;23(9):912-928
Neoplasia (New York, N.Y.) 2021 Sep;23(9):912-928
Human Bone Mesenchymal Stem Cell-Derived Exosomes Inhibit IL-1β-Induced Inflammation in Osteoarthritis Chondrocytes.
Zhou L, Ye H, Liu L, Chen Y
Cell journal 2021 Sep;23(4):485-494
Cell journal 2021 Sep;23(4):485-494
OGT regulated O-GlcNacylation promotes migration and invasion by activating IL-6/STAT3 signaling in NSCLC cells.
Ge X, Peng X, Li M, Ji F, Chen J, Zhang D
Pathology, research and practice 2021 Sep;225:153580
Pathology, research and practice 2021 Sep;225:153580
PPP1CA/YAP/GS/Gln/mTORC1 pathway activates retinal Müller cells during diabetic retinopathy.
Guo Y, Cang X, Zhu L, Zhu M, Li A, Wang Z, Zhang Y, Wang X, Song E
Experimental eye research 2021 Sep;210:108703
Experimental eye research 2021 Sep;210:108703
Interleukin-4 protects mice against lethal influenza and Streptococcus pneumoniae co-infected pneumonia.
Peng Y, Wang X, Wang H, Xu W, Wu K, Go X, Yin Y, Zhang X
Clinical and experimental immunology 2021 Sep;205(3):379-390
Clinical and experimental immunology 2021 Sep;205(3):379-390
MeCP2 prevents age-associated cognitive decline via restoring synaptic plasticity in a senescence-accelerated mouse model.
Huang JL, Zhang F, Su M, Li J, Yi W, Hou LX, Yang SM, Liu JY, Zhang HA, Ma T, Wu DP
Aging cell 2021 Sep;20(9):e13451
Aging cell 2021 Sep;20(9):e13451
P76RBE silencing inhibits ovarian cancer cell proliferation, migration, and invasion via suppressing the integrin β1/NF-κB pathway.
Yan L, He Z, Li W, Liu N, Gao S
Cell cycle (Georgetown, Tex.) 2021 Sep;20(18):1875-1889
Cell cycle (Georgetown, Tex.) 2021 Sep;20(18):1875-1889
Photoresponsive PAMAM-Assembled Nanocarrier Loaded with Autophagy Inhibitor for Synergistic Cancer Therapy.
Jing M, Li Y, Wang M, Zhang H, Wei P, Zhou Y, Ishimwe N, Huang X, Wang L, Wen L, Wang W, Zhang Y
Small (Weinheim an der Bergstrasse, Germany) 2021 Sep;17(38):e2102295
Small (Weinheim an der Bergstrasse, Germany) 2021 Sep;17(38):e2102295
Orf Virus ORF120 Protein Positively Regulates the NF-κB Pathway by Interacting with G3BP1.
Zhou Y, Guan J, Gao F, Li Z, Lan Y, Lu H, Song D, Lv L, Lv P, Xu M, Wang Z, He H, Zhao K, He W
Journal of virology 2021 Sep 9;95(19):e0015321
Journal of virology 2021 Sep 9;95(19):e0015321
NSUN2 modified by SUMO-2/3 promotes gastric cancer progression and regulates mRNA m5C methylation.
Hu Y, Chen C, Tong X, Chen S, Hu X, Pan B, Sun X, Chen Z, Shi X, Hu Y, Shen X, Xue X, Lu M
Cell death & disease 2021 Sep 9;12(9):842
Cell death & disease 2021 Sep 9;12(9):842
HSP90 acts as a senomorphic target in senescent retinal pigmental epithelial cells.
Chen DD, Peng X, Wang Y, Jiang M, Xue M, Shang G, Liu X, Jia X, Liu B, Lu Y, Mu H, Zhang F, Hu Y
Aging 2021 Sep 8;13(17):21547-21570
Aging 2021 Sep 8;13(17):21547-21570
Microglia modulation with 1070-nm light attenuates Aβ burden and cognitive impairment in Alzheimer's disease mouse model.
Tao L, Liu Q, Zhang F, Fu Y, Zhu X, Weng X, Han H, Huang Y, Suo Y, Chen L, Gao X, Wei X
Light, science & applications 2021 Sep 8;10(1):179
Light, science & applications 2021 Sep 8;10(1):179
Cilium induction triggers differentiation of glioma stem cells.
Goranci-Buzhala G, Mariappan A, Ricci-Vitiani L, Josipovic N, Pacioni S, Gottardo M, Ptok J, Schaal H, Callaini G, Rajalingam K, Dynlacht B, Hadian K, Papantonis A, Pallini R, Gopalakrishnan J
Cell reports 2021 Sep 7;36(10):109656
Cell reports 2021 Sep 7;36(10):109656
m6A demethylase ALKBH5 suppression contributes to esophageal squamous cell carcinoma progression.
Xiao D, Fang TX, Lei Y, Xiao SJ, Xia JW, Lin TY, Li YL, Zhai JX, Li XY, Huang SH, Jia JS, Tian YG, Lin XL, Cai KC, Sun Y
Aging 2021 Sep 7;13(17):21497-21512
Aging 2021 Sep 7;13(17):21497-21512
The genomic architecture of EBV and infected gastric tissue from precursor lesions to carcinoma.
Chen ZH, Yan SM, Chen XX, Zhang Q, Liu SX, Liu Y, Luo YL, Zhang C, Xu M, Zhao YF, Huang LY, Liu BL, Xia TL, Xu DZ, Liang Y, Chen YM, Wang W, Yuan SQ, Zhang HZ, Yun JP, Zhai WW, Zeng MS, Bai F, Zhong Q
Genome medicine 2021 Sep 7;13(1):146
Genome medicine 2021 Sep 7;13(1):146
A ciliopathy complex builds distal appendages to initiate ciliogenesis.
Kumar D, Rains A, Herranz-Pérez V, Lu Q, Shi X, Swaney DL, Stevenson E, Krogan NJ, Huang B, Westlake C, Garcia-Verdugo JM, Yoder BK, Reiter JF
The Journal of cell biology 2021 Sep 6;220(9)
The Journal of cell biology 2021 Sep 6;220(9)
TDP-43 mediates SREBF2-regulated gene expression required for oligodendrocyte myelination.
Ho WY, Chang JC, Lim K, Cazenave-Gassiot A, Nguyen AT, Foo JC, Muralidharan S, Viera-Ortiz A, Ong SJM, Hor JH, Agrawal I, Hoon S, Arogundade OA, Rodriguez MJ, Lim SM, Kim SH, Ravits J, Ng SY, Wenk MR, Lee EB, Tucker-Kellogg G, Ling SC
The Journal of cell biology 2021 Sep 6;220(9)
The Journal of cell biology 2021 Sep 6;220(9)
Live Combined B. subtilis and E. faecium Alleviate Liver Inflammation, Improve Intestinal Barrier Function, and Modulate Gut Microbiota in Mice with Non-Alcoholic Fatty Liver Disease.
Jiang J, Xiong J, Ni J, Chen C, Wang K
Medical science monitor : international medical journal of experimental and clinical research 2021 Sep 5;27:e931143
Medical science monitor : international medical journal of experimental and clinical research 2021 Sep 5;27:e931143
Curcumol inhibits encephalomyocarditis virus by promoting IFN-β secretion.
Zheng J, Xu Y, Khan A, Sun P, Sun Y, Fan K, Yin W, Wang S, Li H, Sun N
BMC veterinary research 2021 Sep 30;17(1):318
BMC veterinary research 2021 Sep 30;17(1):318
Stimulation of ROS Generation by Extract of Warburgia ugandensis Leading to G0/G1 Cell Cycle Arrest and Antiproliferation in A549 Cells.
Zhang YL, Chen GL, Liu Y, Zhuang XC, Guo MQ
Antioxidants (Basel, Switzerland) 2021 Sep 30;10(10)
Antioxidants (Basel, Switzerland) 2021 Sep 30;10(10)
HIF-1α/JMJD1A signaling regulates inflammation and oxidative stress following hyperglycemia and hypoxia-induced vascular cell injury.
Zhao M, Wang S, Zuo A, Zhang J, Wen W, Jiang W, Chen H, Liang D, Sun J, Wang M
Cellular & molecular biology letters 2021 Sep 3;26(1):40
Cellular & molecular biology letters 2021 Sep 3;26(1):40
Proximity Labeling, Quantitative Proteomics, and Biochemical Studies Revealed the Molecular Mechanism for the Inhibitory Effect of Indisulam on the Proliferation of Gastric Cancer Cells.
Lu J, Jiang H, Li D, Chen T, Wang Y, Pu Z, Xu G
Journal of proteome research 2021 Sep 3;20(9):4462-4474
Journal of proteome research 2021 Sep 3;20(9):4462-4474
Supervillin Contributes to LPS-induced Inflammatory Response in THP-1 Cell-derived Macrophages.
Zhou J, Que Y, Pan L, Li X, Zhu C, Jin L, Li S
Inflammation 2021 Sep 3;
Inflammation 2021 Sep 3;
Inhibition of DNMT-1 alleviates ferroptosis through NCOA4 mediated ferritinophagy during diabetes myocardial ischemia/reperfusion injury.
Li W, Li W, Wang Y, Leng Y, Xia Z
Cell death discovery 2021 Sep 29;7(1):267
Cell death discovery 2021 Sep 29;7(1):267
A Versatile Nanoplatform for Broad-Spectrum Immunotherapy by Reversing the Tumor Microenvironment.
Chen A, Yang F, Kuang J, Xiong Y, Mi BB, Zhou Y, Hu JJ, Song SJ, Wan T, Wan ZZ, Huang HY, Li XR, Song W, Qiu WX
ACS applied materials & interfaces 2021 Sep 29;13(38):45335-45345
ACS applied materials & interfaces 2021 Sep 29;13(38):45335-45345
Therapeutic Interaction of Apatinib and Chidamide in T-Cell Acute Lymphoblastic Leukemia through Interference with Mitochondria Associated Biogenesis and Intrinsic Apoptosis.
Zhong M, Lin F, Jiang Y, Pan G, Tan J, Zhou H, Lai Q, Chen Q, Deng M, Zha J, Xu B
Journal of personalized medicine 2021 Sep 29;11(10)
Journal of personalized medicine 2021 Sep 29;11(10)
A Novel Calpain Inhibitor Compound Has Protective Effects on a Zebrafish Model of Spinocerebellar Ataxia Type 3.
Robinson KJ, Yuan K, Plenderleith SK, Watchon M, Laird AS
Cells 2021 Sep 29;10(10)
Cells 2021 Sep 29;10(10)
Exosomal microRNA-588 from M2 polarized macrophages contributes to cisplatin resistance of gastric cancer cells.
Cui HY, Rong JS, Chen J, Guo J, Zhu JQ, Ruan M, Zuo RR, Zhang SS, Qi JM, Zhang BH
World journal of gastroenterology 2021 Sep 28;27(36):6079-6092
World journal of gastroenterology 2021 Sep 28;27(36):6079-6092
Engineering Extracellular Vesicles Restore the Impaired Cellular Uptake and Attenuate Intervertebral Disc Degeneration.
Liao Z, Liu H, Ma L, Lei J, Tong B, Li G, Ke W, Wang K, Feng X, Hua W, Li S, Yang C
ACS nano 2021 Sep 28;15(9):14709-14724
ACS nano 2021 Sep 28;15(9):14709-14724
Dual Inhibition of Endoplasmic Reticulum Stress and Oxidation Stress Manipulates the Polarization of Macrophages under Hypoxia to Sensitize Immunotherapy.
Jiang M, Li X, Zhang J, Lu Y, Shi Y, Zhu C, Liu Y, Qin B, Luo Z, Du Y, Luo L, Peng L, You J
ACS nano 2021 Sep 28;15(9):14522-14534
ACS nano 2021 Sep 28;15(9):14522-14534
Regulatory variants at 2q33.1 confer schizophrenia risk by modulating distal gene TYW5 expression.
Li S, Li J, Liu J, Wang J, Li X, Huo Y, Li Y, Liu Y, Li M, Xiao X, Luo XJ
Brain : a journal of neurology 2021 Sep 28;
Brain : a journal of neurology 2021 Sep 28;
Phenotypic and genotypic changes in obesity and type 2 diabetes of male KK mice with aging.
Iizuka Y, Kim H, Nakasatomi M, Matsumoto A, Shimizu J
Experimental animals 2021 Sep 28;
Experimental animals 2021 Sep 28;
Changes in energy metabolism and respiration in different tracheal narrowing in rats.
Segev Y, Nujedat H, Arazi E, Assadi MH, Tarasiuk A
Scientific reports 2021 Sep 27;11(1):19166
Scientific reports 2021 Sep 27;11(1):19166
Protective effects of Huang-Lian-Jie-Du Decoction on diabetic nephropathy through regulating AGEs/RAGE/Akt/Nrf2 pathway and metabolic profiling in db/db mice.
Tang D, He WJ, Zhang ZT, Shi JJ, Wang X, Gu WT, Chen ZQ, Xu YH, Chen YB, Wang SM
Phytomedicine : international journal of phytotherapy and phytopharmacology 2021 Sep 27;:153777
Phytomedicine : international journal of phytotherapy and phytopharmacology 2021 Sep 27;:153777
Macrophage-mediated multi-mode drug release system for photothermal combined with anti-inflammatory therapy against postoperative recurrence of triple negative breast cancer.
Ren K, Qiu Y, Yu Q, He J, Mei L, Liu Y, Li J, Wang X, Li M, Zhang Z, He Q
International journal of pharmaceutics 2021 Sep 25;607:120975
International journal of pharmaceutics 2021 Sep 25;607:120975
EZH2 Inhibitor Enhances the STING Agonist‒Induced Antitumor Immunity in Melanoma.
Xu T, Dai J, Tang L, Yang L, Si L, Sheng X, Cui C, Chi Z, Kong Y, Guo J
The Journal of investigative dermatology 2021 Sep 25;
The Journal of investigative dermatology 2021 Sep 25;
A novel pyrrole-imidazole polyamide targets Aurora kinase A and suppresses tumor growth in vivo.
Li M, Lu D, Cheng Y, Wu C, Zhang J, Shi W, Ding Z, Li Y, Cheng B, Lin X, Shao X, Li H, Fang L, Liu K, Su W
Biochemical and biophysical research communications 2021 Sep 24;571:167-173
Biochemical and biophysical research communications 2021 Sep 24;571:167-173
Metabolic nuclear receptors coordinate energy metabolism to regulate Sox9+ hepatocyte fate.
Liu S, Qin D, Yan Y, Wu J, Meng L, Huang W, Wang L, Chen X, Zhang L
iScience 2021 Sep 24;24(9):103003
iScience 2021 Sep 24;24(9):103003
Downregulation of acylglycerol kinase suppresses high-glucose-induced endothelial-mesenchymal transition in human retinal microvascular endothelial cells through regulating the LPAR1/TGF-β/Notch signaling pathway.
Wang H, Feng Z, Han X, Xing Y, Zhang X
Canadian journal of physiology and pharmacology 2021 Sep 24;:1-9
Canadian journal of physiology and pharmacology 2021 Sep 24;:1-9
Costunolide Loaded in pH-Responsive Mesoporous Silica Nanoparticles for Increased Stability and an Enhanced Anti-Fibrotic Effect.
Niu X, Wang X, Niu B, Meng Y, He H, Wang Y, Li G
Pharmaceuticals (Basel, Switzerland) 2021 Sep 23;14(10)
Pharmaceuticals (Basel, Switzerland) 2021 Sep 23;14(10)
Transgelin-2 interacts with CD44 to regulate Notch1 signaling pathway and participates in colorectal cancer proliferation and migration.
Ding R, Li G, Yao Y, Zhang L, Zhang X, Li J, Shen T, Gao Y, Wu T, Kong S, Huang M, Li Y
Journal of physiology and biochemistry 2021 Sep 23;
Journal of physiology and biochemistry 2021 Sep 23;
Nuclear speckle specific hnRNP D-like prevents age- and AD-related cognitive decline by modulating RNA splicing.
Zhang Q, Zhang J, Ye J, Li X, Liu H, Ma X, Wang C, He K, Zhang W, Yuan J, Zhao Y, Xu H, Liu Q
Molecular neurodegeneration 2021 Sep 22;16(1):66
Molecular neurodegeneration 2021 Sep 22;16(1):66
Xenon Nanobubbles for the Image-Guided Preemptive Treatment of Acute Ischemic Stroke via Neuroprotection and Microcirculatory Restoration.
Jin J, Li M, Li J, Li B, Duan L, Yang F, Gu N
ACS applied materials & interfaces 2021 Sep 22;13(37):43880-43891
ACS applied materials & interfaces 2021 Sep 22;13(37):43880-43891
GPCR-mediated EGFR transactivation ameliorates skin toxicities induced by afatinib.
Chen LY, You Q, Lv DZ, Li SH, Zhang SY
Acta pharmacologica Sinica 2021 Sep 22;
Acta pharmacologica Sinica 2021 Sep 22;
Ferroptosis-related lncRNA pairs to predict the clinical outcome and molecular characteristics of pancreatic ductal adenocarcinoma.
Tang R, Wu Z, Rong Z, Xu J, Wang W, Zhang B, Yu X, Shi S
Briefings in bioinformatics 2021 Sep 22;
Briefings in bioinformatics 2021 Sep 22;
The STING-IRF3 pathway contributes to paraquat-induced acute lung injury.
Wang N, Wang X, Li Y, Shen H, Liu Z, Ma Z, Li Q, Zhao M
Toxicology mechanisms and methods 2021 Sep 21;:1-13
Toxicology mechanisms and methods 2021 Sep 21;:1-13
CD36 and DGAT2 facilitate the lipid-lowering effect of chitooligosaccharides via fatty acid intake and triglyceride synthesis signaling.
Shen X, Liang X, Ji X, You J, Zhuang X, Song Y, Yin H, Zhao M, Zhao L
Food & function 2021 Sep 20;12(18):8681-8693
Food & function 2021 Sep 20;12(18):8681-8693
Isonicotinylation is a histone mark induced by the anti-tuberculosis first-line drug isoniazid.
Jiang Y, Li Y, Liu C, Zhang L, Lv D, Weng Y, Cheng Z, Chen X, Zhan J, Zhang H
Nature communications 2021 Sep 20;12(1):5548
Nature communications 2021 Sep 20;12(1):5548
RIOK2 Inhibitor NSC139021 Exerts Anti-Tumor Effects on Glioblastoma via Inducing Skp2-Mediated Cell Cycle Arrest and Apoptosis.
Yu M, Hu X, Yan J, Wang Y, Lu F, Chang J
Biomedicines 2021 Sep 17;9(9)
Biomedicines 2021 Sep 17;9(9)
Lactobacillus johnsonii L531 Alleviates the Damage Caused by Salmonella Typhimurium via Inhibiting TLR4, NF-κB, and NLRP3 Inflammasome Signaling Pathways.
Chen S, Li Y, Chu B, Yuan L, Liu N, Zhu Y, Wang J
Microorganisms 2021 Sep 17;9(9)
Microorganisms 2021 Sep 17;9(9)
MYO10 drives genomic instability and inflammation in cancer.
Mayca Pozo F, Geng X, Tamagno I, Jackson MW, Heimsath EG, Hammer JA, Cheney RE, Zhang Y
Science advances 2021 Sep 17;7(38):eabg6908
Science advances 2021 Sep 17;7(38):eabg6908
Isopsoralen ameliorates rheumatoid arthritis by targeting MIF.
Han Y, Wang J, Li S, Li Y, Zhang Y, Zhang R, Zhang Y, Fan H, Shi H, Pan J, Song G, Ge L, Wang L
Arthritis research & therapy 2021 Sep 17;23(1):243
Arthritis research & therapy 2021 Sep 17;23(1):243
Flunarizine suppresses Mycobacterium tuberculosis growth via calmodulin-dependent phagosome maturation.
Mo S, Liu X, Zhang K, Wang W, Cai Y, Ouyang Q, Zhu C, Lin D, Wan H, Li D, Wen Z, Chen X
Journal of leukocyte biology 2021 Sep 17;
Journal of leukocyte biology 2021 Sep 17;
MicroRNA-550a-3-5p controls the brain metastasis of lung cancer by directly targeting YAP1.
Wei L, Wang G, Yang C, Zhang Y, Chen Y, Zhong C, Li Q
Cancer cell international 2021 Sep 16;21(1):491
Cancer cell international 2021 Sep 16;21(1):491
EETs/sEHi alleviates nociception by blocking the crosslink between endoplasmic reticulum stress and neuroinflammation in a central poststroke pain model.
Liu T, Li T, Chen X, Li Z, Feng M, Yao W, Wan L, Zhang C, Zhang Y
Journal of neuroinflammation 2021 Sep 16;18(1):211
Journal of neuroinflammation 2021 Sep 16;18(1):211
PRMT5 regulates cell pyroptosis by silencing CASP1 in multiple myeloma.
Xia T, Liu M, Zhao Q, Ouyang J, Xu P, Chen B
Cell death & disease 2021 Sep 16;12(10):851
Cell death & disease 2021 Sep 16;12(10):851
Latcripin-7A from Lentinula edodes C91-3 induces apoptosis, autophagy, and cell cycle arrest at G1 phase in human gastric cancer cells via inhibiting PI3K/Akt/mTOR signaling.
Din SRU, Nisar MA, Ramzan MN, Saleem MZ, Ghayas H, Ahmad B, Batool S, Kifayat K, Guo X, Huang M, Zhong M
European journal of pharmacology 2021 Sep 15;907:174305
European journal of pharmacology 2021 Sep 15;907:174305
Round Scad-Derived Octapeptide WCPFSRSF Confers Neuroprotection by Regulating Akt/Nrf2/NFκB Signaling.
Zhang Q, Su G, Yang Q, Wei Z, Wang J, Zheng L, Zhao M
Journal of agricultural and food chemistry 2021 Sep 15;69(36):10606-10616
Journal of agricultural and food chemistry 2021 Sep 15;69(36):10606-10616
The protection of selenium against cadmium-induced mitophagy via modulating nuclear xenobiotic receptors response and oxidative stress in the liver of rabbits.
Zhang L, Yang F, Li Y, Cao H, Huang A, Zhuang Y, Zhang C, Hu G, Mao Y, Luo J, Xing C
Environmental pollution (Barking, Essex : 1987) 2021 Sep 15;285:117301
Environmental pollution (Barking, Essex : 1987) 2021 Sep 15;285:117301
Co-exposure to BPA and DEHP enhances susceptibility of mammary tumors via up-regulating Esr1/HDAC6 pathway in female rats.
Zhang X, Cheng C, Zhang G, Xiao M, Li L, Wu S, Lu X
Ecotoxicology and environmental safety 2021 Sep 15;221:112453
Ecotoxicology and environmental safety 2021 Sep 15;221:112453
PM2.5-induced lung injury is attenuated in macrophage-specific NLRP3 deficient mice.
Xiong R, Jiang W, Li N, Liu B, He R, Wang B, Geng Q
Ecotoxicology and environmental safety 2021 Sep 15;221:112433
Ecotoxicology and environmental safety 2021 Sep 15;221:112433
Physiologically detectable bisphenol A impairs human sperm functions by reducing protein-tyrosine phosphorylation.
Li N, Kang H, Peng Z, Wang HF, Weng SQ, Zeng XH
Ecotoxicology and environmental safety 2021 Sep 15;221:112418
Ecotoxicology and environmental safety 2021 Sep 15;221:112418
Sigma-1 receptor regulates mitophagy in dopaminergic neurons and contributes to dopaminergic protection.
Wang M, Wan C, He T, Han C, Zhu K, Waddington JL, Zhen X
Neuropharmacology 2021 Sep 15;196:108360
Neuropharmacology 2021 Sep 15;196:108360
Scoparone inhibits pancreatic cancer through PI3K/Akt signaling pathway.
Li N, Yang F, Liu DY, Guo JT, Ge N, Sun SY
World journal of gastrointestinal oncology 2021 Sep 15;13(9):1164-1183
World journal of gastrointestinal oncology 2021 Sep 15;13(9):1164-1183
Quercitrin Rapidly Alleviated Depression-like Behaviors in Lipopolysaccharide-Treated Mice: The Involvement of PI3K/AKT/NF-κB Signaling Suppression and CREB/BDNF Signaling Restoration in the Hippocampus.
Sun Y, Zhang H, Wu Z, Yu X, Yin Y, Qian S, Wang Z, Huang J, Wang W, Liu T, Xue W, Chen G
ACS chemical neuroscience 2021 Sep 15;12(18):3387-3396
ACS chemical neuroscience 2021 Sep 15;12(18):3387-3396
Circular RNA ZNF609 enhances proliferation and glycolysis during glioma progression by miR-378b/SLC2A1 axis.
Zhao Z, Li G, Han Y, Li Y, Ji Z, Guo R, Yu X
Aging 2021 Sep 14;13(17):21122-21133
Aging 2021 Sep 14;13(17):21122-21133
Asiatic acid alleviates ischemic myocardial injury in mice by modulating mitophagy- and glycophagy-based energy metabolism.
Qiu F, Yuan Y, Luo W, Gong YS, Zhang ZM, Liu ZM, Gao L
Acta pharmacologica Sinica 2021 Sep 14;
Acta pharmacologica Sinica 2021 Sep 14;
Protective Effects and Mechanisms of Procyanidins on Parkinson's Disease In Vivo and In Vitro.
Chen J, Chen Y, Zheng Y, Zhao J, Yu H, Zhu J, Li D
Molecules (Basel, Switzerland) 2021 Sep 13;26(18)
Molecules (Basel, Switzerland) 2021 Sep 13;26(18)
Genome-wide mRNA profiling identifies the NRF2-regulated lymphocyte oxidative stress status in patients with silicosis.
Zhao Y, Xu G, Li H, Chang M, Xiong C, Tao Y, Guan Y, Li Y, Yao S
Journal of occupational medicine and toxicology (London, England) 2021 Sep 13;16(1):40
Journal of occupational medicine and toxicology (London, England) 2021 Sep 13;16(1):40
TNFSF9 promotes metastasis of pancreatic cancer through Wnt/Snail signaling and M2 polarization of macrophages.
Wu J, Wang Y, Yang Y, Liu F, Chen J, Jiang Z, Jiang Z
Aging 2021 Sep 13;13(17):21571-21586
Aging 2021 Sep 13;13(17):21571-21586
LPCAT1 reprogramming cholesterol metabolism promotes the progression of esophageal squamous cell carcinoma.
Tao M, Luo J, Gu T, Yu X, Song Z, Jun Y, Gu H, Han K, Huang X, Yu W, Sun S, Zhang Z, Liu L, Chen X, Zhang L, Luo C, Wang Q
Cell death & disease 2021 Sep 13;12(9):845
Cell death & disease 2021 Sep 13;12(9):845
Hypoxia regulates overall mRNA homeostasis by inducing Met1-linked linear ubiquitination of AGO2 in cancer cells.
Zhang H, Zhao X, Guo Y, Chen R, He J, Li L, Qiang Z, Yang Q, Liu X, Huang C, Lu R, Fang J, Cao Y, Huang J, Wang Y, Huang J, Chen GQ, Cheng J, Yu J
Nature communications 2021 Sep 13;12(1):5416
Nature communications 2021 Sep 13;12(1):5416
Ketamine ameliorates depressive-like behaviors in mice through increasing glucose uptake regulated by the ERK/GLUT3 signaling pathway.
Ouyang X, Wang Z, Luo M, Wang M, Liu X, Chen J, Feng J, Jia J, Wang X
Scientific reports 2021 Sep 13;11(1):18181
Scientific reports 2021 Sep 13;11(1):18181
Phosphorylated PAMAM dendrimers: an analog of dentin non-collagenous proteins, enhancing the osteo/odontogenic differentiation of dental pulp stem cells.
Liu J, Gao Y, Zhu X, Zhang Y, Xu H, Wang T, Zhang G
Clinical oral investigations 2021 Sep 13;
Clinical oral investigations 2021 Sep 13;
2,5-dimethyl celecoxib induces apoptosis and autophagy via activation of ROS/JNK axis in nasopharyngeal carcinoma cells.
Tan T, Fu X, Qu J, Zhang M, Chen H, Wang Y, Wang B, Li J, Liu J, Liu P
Aging 2021 Sep 12;13(17):21483-21496
Aging 2021 Sep 12;13(17):21483-21496
A dual-role of SARS-CoV-2 nucleocapsid protein in regulating innate immune response.
Zhao Y, Sui L, Wu P, Wang W, Wang Z, Yu Y, Hou Z, Tan G, Liu Q, Wang G
Signal transduction and targeted therapy 2021 Sep 1;6(1):331
Signal transduction and targeted therapy 2021 Sep 1;6(1):331
MIER3 induces epithelial-mesenchymal transition and promotes breast cancer cell aggressiveness via forming a co-repressor complex with HDAC1/HDAC2/Snail.
Huang W, Chen J, Liu X, Liu X, Duan S, Chen L, Liu X, Lan J, Zou Y, Guo D, Zhou J
Experimental cell research 2021 Sep 1;406(1):112722
Experimental cell research 2021 Sep 1;406(1):112722
Differential expression of microRNAs in human endometrium after implantation of an intrauterine contraceptive device containing copper.
Fan X, Huang J, Xu C, Bao M, Xia W, Zhu C
Molecular human reproduction 2021 Sep 1;27(9)
Molecular human reproduction 2021 Sep 1;27(9)
Formosanin C attenuates lipopolysaccharide-induced inflammation through nuclear factor-κB inhibition in macrophages.
Yin L, Shi C, Zhang Z, Wang W, Li M
The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology 2021 Sep 1;25(5):395-401
The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology 2021 Sep 1;25(5):395-401
A general role for TANGO1, encoded by MIA3, in secretory pathway organization and function.
McCaughey J, Stevenson NL, Mantell JM, Neal CR, Paterson A, Heesom K, Stephens DJ
Journal of cell science 2021 Sep 1;134(17)
Journal of cell science 2021 Sep 1;134(17)
CLEC5A knockdown protects against cardiac dysfunction after myocardial infarction by suppressing macrophage polarization, NLRP3 inflammasome activation, and pyroptosis.
Wang X, Hu Y, Wang Y, Shen D, Tao G
Biochemistry and cell biology = Biochimie et biologie cellulaire 2021 Oct;99(5):655-665
Biochemistry and cell biology = Biochimie et biologie cellulaire 2021 Oct;99(5):655-665
Inhibition of YAP activation attenuates renal injury and fibrosis in angiotensin II hypertensive mice.
Zhang J, Xu Q, Ren F, Liu Y, Cai R, Yao Y, Zhou MS
Canadian journal of physiology and pharmacology 2021 Oct;99(10):1000-1006
Canadian journal of physiology and pharmacology 2021 Oct;99(10):1000-1006
Iguratimod decreases bleomycin-induced pulmonary fibrosis in association with inhibition of TNF-α in mice.
Shao S, Qu Z, Liang Y, Xu Y, Zhou D, Li D, Zhang Y, Yin S
International immunopharmacology 2021 Oct;99:107936
International immunopharmacology 2021 Oct;99:107936
A botanical dietary supplement from white peony and licorice attenuates nonalcoholic fatty liver disease by modulating gut microbiota and reducing inflammation.
Chen L, Kan J, Zheng N, Li B, Hong Y, Yan J, Tao X, Wu G, Ma J, Zhu W, Sheng L, Chen L, Li B, Zhong J, Du J, Li H
Phytomedicine : international journal of phytotherapy and phytopharmacology 2021 Oct;91:153693
Phytomedicine : international journal of phytotherapy and phytopharmacology 2021 Oct;91:153693
USP41 promotes breast cancer via regulating RACK1.
Huang M, Xiao J, Yan C, Wang T, Ling R
Annals of translational medicine 2021 Oct;9(20):1566
Annals of translational medicine 2021 Oct;9(20):1566
MYO1B enhances colorectal cancer metastasis by promoting the F-actin rearrangement and focal adhesion assembly via RhoA/ROCK/FAK signaling.
Xie L, Huang H, Zheng Z, Yang Q, Wang S, Chen Y, Yu J, Cui C
Annals of translational medicine 2021 Oct;9(20):1543
Annals of translational medicine 2021 Oct;9(20):1543
MET overexpression contributes to STAT4-PD-L1 signaling activation associated with tumor-associated, macrophages-mediated immunosuppression in primary glioblastomas.
Wang QW, Sun LH, Zhang Y, Wang Z, Zhao Z, Wang ZL, Wang KY, Li GZ, Xu JB, Ren CY, Ma WP, Wang HJ, Li SW, Zhu YJ, Jiang T, Bao ZS
Journal for immunotherapy of cancer 2021 Oct;9(10)
Journal for immunotherapy of cancer 2021 Oct;9(10)
Concentrated growth factor regulates the macrophage-mediated immune response.
Luo H, Liu W, Zhou Y, Jiang X, Liu Y, Yang Q, Shao L
Regenerative biomaterials 2021 Oct;8(6):rbab049
Regenerative biomaterials 2021 Oct;8(6):rbab049
YAP drives fate conversion and chemoresistance of small cell lung cancer.
Wu Q, Guo J, Liu Y, Zheng Q, Li X, Wu C, Fang D, Chen X, Ma L, Xu P, Xu X, Liao C, Wu M, Shen L, Song H
Science advances 2021 Oct;7(40):eabg1850
Science advances 2021 Oct;7(40):eabg1850
Distinct pathogenic mechanisms of various RARS1 mutations in Pelizaeus-Merzbacher-like disease.
Li G, Eriani G, Wang ED, Zhou XL
Science China. Life sciences 2021 Oct;64(10):1645-1660
Science China. Life sciences 2021 Oct;64(10):1645-1660
Establishment of a second generation homozygous CRISPRa human induced pluripotent stem cell (hiPSC) line for enhanced levels of endogenous gene activation.
Schoger E, Zimmermann WH, Cyganek L, Zelarayán LC
Stem cell research 2021 Oct;56:102518
Stem cell research 2021 Oct;56:102518
Serine/threonine kinase 17b (STK17B) signalling regulates Purkinje cell dendritic development and is altered in multiple spinocerebellar ataxias.
Wu QW, Kapfhammer JP
The European journal of neuroscience 2021 Oct;54(7):6673-6684
The European journal of neuroscience 2021 Oct;54(7):6673-6684
ErbB4 mediates amyloid β-induced neurotoxicity through JNK/tau pathway activation: Implications for Alzheimer's disease.
Zhang H, Zhang L, Zhou D, Li H, Xu Y
The Journal of comparative neurology 2021 Oct;529(15):3497-3512
The Journal of comparative neurology 2021 Oct;529(15):3497-3512
Functional expression of TRPA1 channel, TRPV1 channel and TMEM100 in human odontoblasts.
Liu Y, Wang Y, Lou Y, Tian W, Que K
Journal of molecular histology 2021 Oct;52(5):1105-1114
Journal of molecular histology 2021 Oct;52(5):1105-1114
GFI1 promotes the proliferation and migration of esophageal squamous cell carcinoma cells through the inhibition of SOCS1 expression.
Huang Y, Ruan R, Fang Y, Wu K, Yao L, Zhang R, He W
International journal of molecular medicine 2021 Oct;48(4)
International journal of molecular medicine 2021 Oct;48(4)
Lactate and glutamine support NADPH generation in cancer cells under glucose deprived conditions.
Ying M, You D, Zhu X, Cai L, Zeng S, Hu X
Redox biology 2021 Oct;46:102065
Redox biology 2021 Oct;46:102065
Mono-macrophage-Derived MANF Alleviates Bacterial Myocarditis by Inhibiting NF-kappaB Activation and Myocardial Inflammation.
Wang C, Bao Q, Hou C, Sun M, Song X, Cao S, Wang X, Shen Q, Zhao Y, Wang D
Inflammation 2021 Oct;44(5):1916-1926
Inflammation 2021 Oct;44(5):1916-1926
Cystatin F acts as a mediator of immune suppression in glioblastoma.
Senjor E, Perišić Nanut M, Breznik B, Mitrović A, Mlakar J, Rotter A, Porčnik A, Lah Turnšek T, Kos J
Cellular oncology (Dordrecht) 2021 Oct;44(5):1051-1063
Cellular oncology (Dordrecht) 2021 Oct;44(5):1051-1063
Gossypol, a novel modulator of VCP, induces autophagic degradation of mutant huntingtin by promoting the formation of VCP/p97-LC3-mHTT complex.
Li XJ, Zhang YY, Fu YH, Zhang H, Li HX, Li QF, Li HL, Tan RK, Jiang CX, Jiang W, Li ZX, Luo C, Lu BX, Dang YJ
Acta pharmacologica Sinica 2021 Oct;42(10):1556-1566
Acta pharmacologica Sinica 2021 Oct;42(10):1556-1566
Nicotinamide phosphoribosyltransferase inhibitor ameliorates mouse aging-induced cognitive impairment.
Zeng M, Wei TF, Chen C, Shen C, Gao TY, Xie X, Wu M, Lu YB, Zhang WP
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2021 Oct;41(10):2510-2523
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2021 Oct;41(10):2510-2523
High-content screening of diterpenoids from Isodon species as autophagy modulators and the functional study of their antiviral activities.
Huang L, Fu Q, Dai JM, Yan BC, Wang D, Puno PT, Yue J
Cell biology and toxicology 2021 Oct;37(5):695-713
Cell biology and toxicology 2021 Oct;37(5):695-713
Role of Intracellular Distribution of Feline and Bovine SAMHD1 Proteins in Lentiviral Restriction.
Wang C, Meng L, Wang J, Zhang K, Duan S, Ren P, Wei Y, Fu X, Yu B, Wu J, Yu X
Virologica Sinica 2021 Oct;36(5):981-996
Virologica Sinica 2021 Oct;36(5):981-996
SETD8 involved in the progression of inflammatory bowel disease via epigenetically regulating p62 expression.
Chen P, Zhu H, Mao Y, Zhuo M, Yu Y, Chen M, Zhao Q, Li L, Wu M, Ye M
Journal of gastroenterology and hepatology 2021 Oct;36(10):2850-2863
Journal of gastroenterology and hepatology 2021 Oct;36(10):2850-2863
Therapeutic potential of isobavachalcone, a natural flavonoid, in murine experimental colitis by inhibiting NF-κB p65.
Zhou Y, Zhong B, Min X, Hou Y, Lin L, Wu Q, Shi J, Chen X
Phytotherapy research : PTR 2021 Oct;35(10):5861-5870
Phytotherapy research : PTR 2021 Oct;35(10):5861-5870
Pericytes augment glioblastoma cell resistance to temozolomide through CCL5-CCR5 paracrine signaling.
Zhang XN, Yang KD, Chen C, He ZC, Wang QH, Feng H, Lv SQ, Wang Y, Mao M, Liu Q, Tan YY, Wang WY, Li TR, Che LR, Qin ZY, Wu LX, Luo M, Luo CH, Liu YQ, Yin W, Wang C, Guo HT, Li QR, Wang B, Chen W, Wang S, Shi Y, Bian XW, Ping YF
Cell research 2021 Oct;31(10):1072-1087
Cell research 2021 Oct;31(10):1072-1087
Bakuchiol ameliorates cerebral ischemia-reperfusion injury by modulating NLRP3 inflammasome and Nrf2 signaling.
Xu Y, Gao X, Wang L, Yang M, Xie R
Respiratory physiology & neurobiology 2021 Oct;292:103707
Respiratory physiology & neurobiology 2021 Oct;292:103707
Vitamin D decreases Porphyromonas gingivalis internalized into macrophages by promoting autophagy.
Niu L, Chen S, Yang X, Ma C, Pan C, Wang H, Li Q, Geng F, Tang X
Oral diseases 2021 Oct;27(7):1775-1788
Oral diseases 2021 Oct;27(7):1775-1788
High-Throughput Screening to Identify Small Molecules That Selectively Inhibit APOL1 Protein Level in Podocytes.
Choy J, Kan Y, Cifelli S, Johnson J, Chen M, Shiao LL, Zhou H, Previs S, Lei Y, Johnstone R, Liaw A, Saigal A, Hu L, Ramos R, Visconti R, McElroy WT, Kreamer A, Wildey MJ, Peier A, Shin MK, Imbriglio J, Ren Z, Hoek M, Weinglass A, Ai X
SLAS discovery : advancing life sciences R & D 2021 Oct;26(9):1225-1237
SLAS discovery : advancing life sciences R & D 2021 Oct;26(9):1225-1237
Oridonin prevents oxidative stress-induced endothelial injury via promoting Nrf-2 pathway in ischaemic stroke.
Li L, Cheng SQ, Guo W, Cai ZY, Sun YQ, Huang XX, Yang J, Ji J, Chen YY, Dong YF, Cheng H, Sun XL
Journal of cellular and molecular medicine 2021 Oct;25(20):9753-9766
Journal of cellular and molecular medicine 2021 Oct;25(20):9753-9766
Hydrogen sulphide reduced the accumulation of lipid droplets in cardiac tissues of db/db mice via Hrd1 S-sulfhydration.
Sun Y, Zhang L, Lu B, Wen J, Wang M, Zhang S, Li Q, Shu F, Lu F, Liu N, Peng S, Zhao Y, Dong S, Lu F, Zhang W, Wang Y
Journal of cellular and molecular medicine 2021 Oct;25(19):9154-9167
Journal of cellular and molecular medicine 2021 Oct;25(19):9154-9167
SPOP promotes CDCA5 degradation to regulate prostate cancer progression via the AKT pathway.
Luo Z, Wang J, Zhu Y, Sun X, He C, Cai M, Ma J, Wang Y, Han S
Neoplasia (New York, N.Y.) 2021 Oct;23(10):1037-1047
Neoplasia (New York, N.Y.) 2021 Oct;23(10):1037-1047
Knockdown of ALDH1A3 reduces breast cancer stem cell marker CD44 via the miR-7-TGFBR2-Smad3-CD44 regulatory axis.
Pan M, Li M, Guo M, Zhou H, Xu H, Zhao F, Mei F, Xue R, Dou J
Experimental and therapeutic medicine 2021 Oct;22(4):1093
Experimental and therapeutic medicine 2021 Oct;22(4):1093
Establishment of incontinence-associated dermatitis rat models and assessment of the therapeutic effects of zinc oxide, painless skin protective film and silicone dressing.
Chen G, Huang L, Chen Y, Zheng S, Zhu L, Ding M
Experimental and therapeutic medicine 2021 Oct;22(4):1058
Experimental and therapeutic medicine 2021 Oct;22(4):1058
The adjuvanticity of manganese for microbial vaccines via activating the IRF5 signaling pathway.
Cui C, Wang S, Lu W, Wang Y, Li J, Qu K, Yang M, Wang L, Yu Y
Biochemical pharmacology 2021 Oct;192:114720
Biochemical pharmacology 2021 Oct;192:114720
PPARα agonist WY-14,643 induces adipose atrophy and fails to blunt chronic ethanol-induced hepatic fat accumulation in mice lacking adipose FGFR1.
Xu Y, Denning KL, Lu Y
Biochemical pharmacology 2021 Oct;192:114678
Biochemical pharmacology 2021 Oct;192:114678
Nestin Is Required for Spindle Assembly and Cell-Cycle Progression in Glioblastoma Cells.
Wang Q, Wu H, Hu J, Fu H, Qu Y, Yang Y, Cai KQ, Efimov A, Wu M, Yen T, Wang Y, Yang ZJ
Molecular cancer research : MCR 2021 Oct;19(10):1651-1665
Molecular cancer research : MCR 2021 Oct;19(10):1651-1665
Membrane-Associated RING-CH 8 Functions as a Novel PD-L1 E3 Ligase to Mediate PD-L1 Degradation Induced by EGFR Inhibitors.
Qian G, Guo J, Vallega KA, Hu C, Chen Z, Deng Y, Wang Q, Fan S, Ramalingam SS, Owonikoko TK, Wei W, Sun SY
Molecular cancer research : MCR 2021 Oct;19(10):1622-1634
Molecular cancer research : MCR 2021 Oct;19(10):1622-1634
4,4'-Dimethoxychalcone regulates redox homeostasis by targeting riboflavin metabolism in Parkinson's disease therapy.
Gong J, Zhang W, Ding L, Zhang M, Zheng S, Ma R, Tang J, Yi W, Xu H, Zhang Y
Free radical biology & medicine 2021 Oct;174:40-56
Free radical biology & medicine 2021 Oct;174:40-56
TSPAN1 promotes autophagy flux and mediates cooperation between WNT-CTNNB1 signaling and autophagy via the MIR454-FAM83A-TSPAN1 axis in pancreatic cancer.
Zhou C, Liang Y, Zhou L, Yan Y, Liu N, Zhang R, Huang Y, Wang M, Tang Y, Ali DW, Wang Y, Michalak M, Chen XZ, Tang J
Autophagy 2021 Oct;17(10):3175-3195
Autophagy 2021 Oct;17(10):3175-3195
Intrinsic bioactivity of black phosphorus nanomaterials on mitotic centrosome destabilization through suppression of PLK1 kinase.
Shao X, Ding Z, Zhou W, Li Y, Li Z, Cui H, Lin X, Cao G, Cheng B, Sun H, Li M, Liu K, Lu D, Geng S, Shi W, Zhang G, Song Q, Chen L, Wang G, Su W, Cai L, Fang L, Leong DT, Li Y, Yu XF, Li H
Nature nanotechnology 2021 Oct;16(10):1150-1160
Nature nanotechnology 2021 Oct;16(10):1150-1160
Inhibition of sEH via stabilizing the level of EETs alleviated Alzheimer's disease through GSK3β signaling pathway.
Sun CP, Zhang XY, Zhou JJ, Huo XK, Yu ZL, Morisseau C, Hammock BD, Ma XC
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2021 Oct;156:112516
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2021 Oct;156:112516
Inhibition of autophagy with Chloroquine enhanced apoptosis induced by 5-aminolevulinic acid-photodynamic therapy in secondary hyperparathyroidism primary cells and organoids.
Zeng L, Zou Q, Huang P, Xiong L, Cheng Y, Chen Q, Li Y, He H, Yi W, Wei W
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Oct;142:111994
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Oct;142:111994
Synergic radiosensitization of sinomenine hydrochloride and radioiodine on human papillary thyroid carcinoma cells.
Zhao A, Zhang J, Liu Y, Jia X, Lu X, Wang Q, Ji T, Yang L, Xue J, Gao R, Yu Y, Yang A
Translational oncology 2021 Oct;14(10):101172
Translational oncology 2021 Oct;14(10):101172
ATG16L2 overexpression is associated with a good prognosis in colorectal cancer.
Tang J, Wang D, Shen Y, Xue F
Journal of gastrointestinal oncology 2021 Oct;12(5):2192-2202
Journal of gastrointestinal oncology 2021 Oct;12(5):2192-2202
KIF2C: a novel link between Wnt/β-catenin and mTORC1 signaling in the pathogenesis of hepatocellular carcinoma.
Wei S, Dai M, Zhang C, Teng K, Wang F, Li H, Sun W, Feng Z, Kang T, Guan X, Xu R, Cai M, Xie D
Protein & cell 2021 Oct;12(10):788-809
Protein & cell 2021 Oct;12(10):788-809
Travelling ultrasound promotes vasculogenesis of three-dimensional-monocultured human umbilical vein endothelial cells.
Imashiro C, Azuma T, Itai S, Kuribara T, Totani K, Onoe H, Takemura K
Biotechnology and bioengineering 2021 Oct;118(10):3760-3769
Biotechnology and bioengineering 2021 Oct;118(10):3760-3769
Transcription factor POU4F2 promotes colorectal cancer cell migration and invasion through hedgehog-mediated epithelial-mesenchymal transition.
Guo K, Wang P, Zhang L, Zhou Y, Dai X, Yan Y, Chen Y, Wasan HS, Yu J, Ruan S, Sun L
Cancer science 2021 Oct;112(10):4176-4186
Cancer science 2021 Oct;112(10):4176-4186
PD0325901, an ERK inhibitor, enhances the efficacy of PD-1 inhibitor in non-small cell lung carcinoma.
Luo M, Xia Y, Wang F, Zhang H, Su D, Su C, Yang C, Wu S, An S, Lin S, Fu L
Acta pharmaceutica Sinica. B 2021 Oct;11(10):3120-3133
Acta pharmaceutica Sinica. B 2021 Oct;11(10):3120-3133
Cordycepin inhibits cell senescence by ameliorating lysosomal dysfunction and inducing autophagy through the AMPK and mTOR-p70S6K pathway.
Zuo SQ, Li C, Liu YL, Tan YH, Wan X, Xu T, Li Q, Wang L, Wu YL, Deng FM, Tang B
FEBS open bio 2021 Oct;11(10):2705-2714
FEBS open bio 2021 Oct;11(10):2705-2714
Curcumin attenuates Adriamycin-resistance of acute myeloid leukemia by inhibiting the lncRNA HOTAIR/miR-20a-5p/WT1 axis.
Liu JM, Li M, Luo W, Sun HB
Laboratory investigation; a journal of technical methods and pathology 2021 Oct;101(10):1308-1317
Laboratory investigation; a journal of technical methods and pathology 2021 Oct;101(10):1308-1317
FNDC4 acts as an extracellular factor to promote the invasiveness of hepatocellular carcinoma partly via the PI3K/Akt signalling pathway.
Wang B, Zheng B, Lu Y, Huang D, Liu J, Song J, Zheng S
Cancer medicine 2021 Oct;10(20):7242-7252
Cancer medicine 2021 Oct;10(20):7242-7252
Myosin 1f-mediated activation of microglia contributes to the photoreceptor degeneration in a mouse model of retinal detachment.
Wang Y, Zhao X, Gao M, Wan X, Guo Y, Qu Y, Chen Y, Li T, Liu H, Jiang M, Wang F, Sun X
Cell death & disease 2021 Oct 9;12(10):926
Cell death & disease 2021 Oct 9;12(10):926
Serum Level of Tumor-Overexpressed AGR2 Is Significantly Associated with Unfavorable Prognosis of Canine Malignant Mammary Tumors.
Yuan SH, Chang SC, Huang Y, Liu HP
Animals : an open access journal from MDPI 2021 Oct 9;11(10)
Animals : an open access journal from MDPI 2021 Oct 9;11(10)
Disruption of the mouse Bmal1 locus promotes heterotopic ossification with aging via TGF-beta/BMP signaling.
Liang Q, Lu Y, Yu L, Zhu Q, Xie W, Wang Y, Ye L, Li Q, Liu S, Liu Y, Zhu C
Journal of bone and mineral metabolism 2021 Oct 9;
Journal of bone and mineral metabolism 2021 Oct 9;
Metformin accelerates zebrafish heart regeneration by inducing autophagy.
Xie F, Xu S, Lu Y, Wong KF, Sun L, Hasan KMM, Ma ACH, Tse G, Manno SHC, Tian L, Yue J, Cheng SH
NPJ Regenerative medicine 2021 Oct 8;6(1):62
NPJ Regenerative medicine 2021 Oct 8;6(1):62
Extracellular AGR2 activates neighboring fibroblasts through endocytosis and direct binding to β-catenin that requires AGR2 dimerization and adhesion domains.
Merugu SB, Zhou B, Mangukiya HB, Negi H, Ghulam R, Roy D, Qudsia S, Wang Z, Mashausi DS, Yunus FU, Liu GS, Li D
Biochemical and biophysical research communications 2021 Oct 8;573:86-92
Biochemical and biophysical research communications 2021 Oct 8;573:86-92
Adenylyl cyclase 3 regulates osteocyte mechanotransduction and primary cilium.
Duffy MP, Sup ME, Guo XE
Biochemical and biophysical research communications 2021 Oct 8;573:145-150
Biochemical and biophysical research communications 2021 Oct 8;573:145-150
Targeting MUS81 promotes the anticancer effect of WEE1 inhibitor and immune checkpoint blocking combination therapy via activating cGAS/STING signaling in gastric cancer cells.
Li C, Shen Q, Zhang P, Wang T, Liu W, Li R, Ma X, Zeng X, Yin Y, Tao K
Journal of experimental & clinical cancer research : CR 2021 Oct 8;40(1):315
Journal of experimental & clinical cancer research : CR 2021 Oct 8;40(1):315
Inhibition of immunoproteasome subunit low molecular mass polypeptide 7 with ONX-0914 improves hypoxic-ischemic brain damage via PI3K/Akt signaling.
Zhou Y, Gou Z, Huang L, Fan Y, Zhang F, Lu L
Neuroreport 2021 Oct 6;32(14):1206-1215
Neuroreport 2021 Oct 6;32(14):1206-1215
PDCD4 Simultaneously Promotes Microglia Activation via PDCD4-MAPK-NF-κB Positive Loop and Facilitates Neuron Apoptosis During Neuroinflammation.
Chen Q, Lu H, Duan C, Zhu X, Zhang Y, Li M, Zhang D
Inflammation 2021 Oct 6;
Inflammation 2021 Oct 6;
Thymosin beta 4 alleviates non-alcoholic fatty liver by inhibiting ferroptosis via up-regulation of GPX4.
Zhu Z, Zhang Y, Huang X, Can L, Zhao X, Wang Y, Xue J, Cheng M, Zhu L
European journal of pharmacology 2021 Oct 5;908:174351
European journal of pharmacology 2021 Oct 5;908:174351
CDC42EP3 is a key promoter involved in the development and progression of gastric cancer.
Chen W, Zhu Y, Zhang W, Zhang H, Zhou Y, Sun P, Wu G
Carcinogenesis 2021 Oct 5;42(9):1179-1188
Carcinogenesis 2021 Oct 5;42(9):1179-1188
Infantile spasms-linked Nedd4-2 mediates hippocampal plasticity and learning via cofilin signaling.
Lee KY, Zhu J, Cutia CA, Christian-Hinman CA, Rhodes JS, Tsai NP
EMBO reports 2021 Oct 5;22(10):e52645
EMBO reports 2021 Oct 5;22(10):e52645
Cathepsin B Regulates Mice Granulosa Cells' Apoptosis and Proliferation In Vitro.
Chen C, Ahmad MJ, Ye T, Du C, Zhang X, Liang A, Yang L
International journal of molecular sciences 2021 Oct 31;22(21)
International journal of molecular sciences 2021 Oct 31;22(21)
Newcastle disease virus degrades SIRT3 via PINK1-PRKN-dependent mitophagy to reprogram energy metabolism in infected cells.
Gong Y, Tang N, Liu P, Sun Y, Lu S, Liu W, Tan L, Song C, Qiu X, Liao Y, Yu S, Liu X, Lin SH, Ding C
Autophagy 2021 Oct 31;:1-19
Autophagy 2021 Oct 31;:1-19
FAIM regulates autophagy through glutaminolysis in lung adenocarcinoma.
Han T, Wang P, Wang Y, Xun W, Lei J, Wang T, Lu Z, Gan M, Zhang W, Yu B, Wang JB
Autophagy 2021 Oct 31;:1-17
Autophagy 2021 Oct 31;:1-17
Lipophagy deficiency exacerbates ectopic lipid accumulation and tubular cells injury in diabetic nephropathy.
Han Y, Xiong S, Zhao H, Yang S, Yang M, Zhu X, Jiang N, Xiong X, Gao P, Wei L, Xiao Y, Sun L
Cell death & disease 2021 Oct 30;12(11):1031
Cell death & disease 2021 Oct 30;12(11):1031
Jian-Pi-Yi-Shen formula enhances perindopril inhibition of chronic kidney disease progression by activation of SIRT3, modulation of mitochondrial dynamics, and antioxidant effects.
Liu X, Deng R, Wei X, Wang Y, Weng J, Lao Y, Lu J, Xiong G, Li S
Bioscience reports 2021 Oct 29;41(10)
Bioscience reports 2021 Oct 29;41(10)
AnnexinA7 promotes epithelial-mesenchymal transition by interacting with Sorcin and contributes to aggressiveness in hepatocellular carcinoma.
Ling F, Zhang H, Sun Y, Meng J, Sanches JGP, Huang H, Zhang Q, Yu X, Wang B, Hou L, Zhang J
Cell death & disease 2021 Oct 29;12(11):1018
Cell death & disease 2021 Oct 29;12(11):1018
CD146 as a promising therapeutic target for retinal and choroidal neovascularization diseases.
Xue B, Wang P, Yu W, Feng J, Li J, Zhao R, Yang Z, Yan X, Duan H
Science China. Life sciences 2021 Oct 29;
Science China. Life sciences 2021 Oct 29;
RCAN1.4 attenuates renal fibrosis through inhibiting calcineurin-mediated nuclear translocation of NFAT2.
Zhang J, Chen H, Weng X, Liu H, Chen Z, Huang Q, Wang L, Liu X
Cell death discovery 2021 Oct 27;7(1):317
Cell death discovery 2021 Oct 27;7(1):317
Chitosan oligosaccharides packaged into rat adipose mesenchymal stem cells-derived extracellular vesicles facilitating cartilage injury repair and alleviating osteoarthritis.
Li S, Liu J, Liu S, Jiao W, Wang X
Journal of nanobiotechnology 2021 Oct 26;19(1):343
Journal of nanobiotechnology 2021 Oct 26;19(1):343
Clonal hematopoiesis with JAK2V617F promotes pulmonary hypertension with ALK1 upregulation in lung neutrophils.
Kimishima Y, Misaka T, Yokokawa T, Wada K, Ueda K, Sugimoto K, Minakawa K, Nakazato K, Ishida T, Oshima M, Koide S, Shide K, Shimoda K, Iwama A, Ikeda K, Takeishi Y
Nature communications 2021 Oct 26;12(1):6177
Nature communications 2021 Oct 26;12(1):6177
Identification of novel key genes associated with the metastasis of prostate cancer based on bioinformatics prediction and validation.
Song F, Zhang Y, Pan Z, Hu X, Yi Y, Zheng X, Wei H, Huang P
Cancer cell international 2021 Oct 25;21(1):559
Cancer cell international 2021 Oct 25;21(1):559
Lnc-DC promotes estrogen independent growth and tamoxifen resistance in breast cancer.
Peng WX, Koirala P, Zhou H, Jiang J, Zhang Z, Yang L, Mo YY
Cell death & disease 2021 Oct 25;12(11):1000
Cell death & disease 2021 Oct 25;12(11):1000
Loss of TDP-43 function underlies hippocampal and cortical synaptic deficits in TDP-43 proteinopathies.
Ni J, Ren Y, Su T, Zhou J, Fu C, Lu Y, Li D, Zhao J, Li Y, Zhang Y, Fang Y, Liu N, Geng Y, Chen Y
Molecular psychiatry 2021 Oct 25;
Molecular psychiatry 2021 Oct 25;
PFOS facilitates liver inflammation and steatosis: An involvement of NLRP3 inflammasome-mediated hepatocyte pyroptosis.
Qin Y, Gu T, Ling J, Luo J, Zhao J, Hu B, Hua L, Wan C, Jiang S
Journal of applied toxicology : JAT 2021 Oct 23;
Journal of applied toxicology : JAT 2021 Oct 23;
Crocetin suppresses angiogenesis and metastasis through inhibiting sonic hedgehog signaling pathway in gastric cancer.
Zang M, Hou J, Huang Y, Wang J, Ding X, Zhang B, Wang Y, Xuan Y, Zhou Y
Biochemical and biophysical research communications 2021 Oct 22;576:86-92
Biochemical and biophysical research communications 2021 Oct 22;576:86-92
Circular RNA circUBE2J2 acts as the sponge of microRNA-370-5P to suppress hepatocellular carcinoma progression.
Zhang L, Liu Y, Tao H, Zhu H, Pan Y, Li P, Liang H, Zhang B, Song J
Cell death & disease 2021 Oct 22;12(11):985
Cell death & disease 2021 Oct 22;12(11):985
CHD8 safeguards early neuroectoderm differentiation in human ESCs and protects from apoptosis during neurogenesis.
Ding S, Lan X, Meng Y, Yan C, Li M, Li X, Chen J, Jiang W
Cell death & disease 2021 Oct 22;12(11):981
Cell death & disease 2021 Oct 22;12(11):981
cGAS guards against chromosome end-to-end fusions during mitosis and facilitates replicative senescence.
Li X, Li X, Xie C, Cai S, Li M, Jin H, Wu S, Cui J, Liu H, Zhao Y
Protein & cell 2021 Oct 22;
Protein & cell 2021 Oct 22;
Kinesin family member 2C promotes hepatocellular carcinoma growth and metastasis via activating MEK/ERK pathway.
Ding Q, Jiang C, Zhou Y, Duan J, Lai J, Jiang M, Lin D
Bioscience, biotechnology, and biochemistry 2021 Oct 21;85(11):2241-2249
Bioscience, biotechnology, and biochemistry 2021 Oct 21;85(11):2241-2249
CD93 a potential player in cytotrophoblast and endothelial cell migration.
Fantone S, Tossetta G, Di Simone N, Tersigni C, Scambia G, Marcheggiani F, Giannubilo SR, Marzioni D
Cell and tissue research 2021 Oct 21;
Cell and tissue research 2021 Oct 21;
FGGY carbohydrate kinase domain containing is expressed and alternatively spliced in skeletal muscle and attenuates MAP kinase and Akt signaling.
Smith AL, Gjoka E, Izhar M, Novo KJ, Mason BC, De Las Casas A, Waddell DS
Gene 2021 Oct 20;800:145836
Gene 2021 Oct 20;800:145836
FERM domain-containing protein 6 exerts a tumor-inhibiting role in thyroid cancer by antagonizing oncogenic YAP1.
Wang W, Zhao C, Quan F, Zhang P, Shao Y, Liu L
BioFactors (Oxford, England) 2021 Oct 20;
BioFactors (Oxford, England) 2021 Oct 20;
TM7SF2 regulates cell proliferation and apoptosis by activation of C-Raf/ERK pathway in cervical cancer.
Xu Y, Chen X, Pan S, Wang ZW, Zhu X
Cell death discovery 2021 Oct 19;7(1):299
Cell death discovery 2021 Oct 19;7(1):299
Protective Roles of Xijiao Dihuang Tang on Coronary Artery Injury in Kawasaki Disease.
Zhang J, Zhuge Y, Rong X, Ni C, Niu C, Wen Z, Lin H, Chu M, Jia C
Cardiovascular drugs and therapy 2021 Oct 19;
Cardiovascular drugs and therapy 2021 Oct 19;
An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.
Zhang Y, Shang L, Zhang J, Liu Y, Jin C, Zhao Y, Lei X, Wang W, Xiao X, Zhang X, Liu Y, Liu L, Zhuang MW, Mi Q, Tian C, Wang J, He F, Wang PH, Wang J
Cell chemical biology 2021 Oct 19;
Cell chemical biology 2021 Oct 19;
Overexpression of FGF2 delays the progression of osteonecrosis of the femoral head activating the PI3K/Akt signaling pathway.
Lu P, Shen YM, Hua T, Pan T, Chen G, Dai T, Shi KQ
Journal of orthopaedic surgery and research 2021 Oct 18;16(1):613
Journal of orthopaedic surgery and research 2021 Oct 18;16(1):613
Palmitoylation targets the calcineurin phosphatase to the phosphatidylinositol 4-kinase complex at the plasma membrane.
Ulengin-Talkish I, Parson MAH, Jenkins ML, Roy J, Shih AZL, St-Denis N, Gulyas G, Balla T, Gingras AC, Várnai P, Conibear E, Burke JE, Cyert MS
Nature communications 2021 Oct 18;12(1):6064
Nature communications 2021 Oct 18;12(1):6064
Noncanonical Wnt5a signaling regulates tendon stem/progenitor cells senescence.
Chen M, Li Y, Xiao L, Dai G, Lu P, Rui Y
Stem cell research & therapy 2021 Oct 18;12(1):544
Stem cell research & therapy 2021 Oct 18;12(1):544
Human mesenchymal stem cells derived exosomes inhibit the growth of acute myeloid leukemia cells via regulating miR-23b-5p/TRIM14 pathway.
Cheng H, Ding J, Tang G, Huang A, Gao L, Yang J, Chen L
Molecular medicine (Cambridge, Mass.) 2021 Oct 16;27(1):128
Molecular medicine (Cambridge, Mass.) 2021 Oct 16;27(1):128
INTS6 promotes colorectal cancer progression by activating of AKT and ERK signaling.
Ding X, Chen T, Shi Q, Nan P, Wang X, Xie D, Li J
Experimental cell research 2021 Oct 15;407(2):112826
Experimental cell research 2021 Oct 15;407(2):112826
T-lymphoma invasion and metastasis 1 promotes invadopodia formation and is regulated by the PI3K/Akt signaling pathway in hepatocellular carcinoma.
Wang B, Zheng B, Cao L, Liao K, Huang D, Zhang Y, Jiang Y, Zheng S
Experimental cell research 2021 Oct 15;407(2):112806
Experimental cell research 2021 Oct 15;407(2):112806
The expression of IFN-β is suppressed by the viral 3D polymerase via its impact on PGAM5 expression during enterovirus D68 infection.
Yang Z, Zheng H, Li H, Chen Y, Hou D, Fan Q, Song J, Guo L, Liu L
Virus research 2021 Oct 15;304:198549
Virus research 2021 Oct 15;304:198549
Design, synthesis, and biological evaluation of 2,4-diamino pyrimidine derivatives as potent FAK inhibitors with anti-cancer and anti-angiogenesis activities.
Wang S, Zhang RH, Zhang H, Wang YC, Yang D, Zhao YL, Yan GY, Xu GB, Guan HY, Zhou YH, Cui DB, Liu T, Li YJ, Liao SG, Zhou M
European journal of medicinal chemistry 2021 Oct 15;222:113573
European journal of medicinal chemistry 2021 Oct 15;222:113573
HBeAg mediates inflammatory functions of macrophages by TLR2 contributing to hepatic fibrosis.
Xie X, Lv H, Liu C, Su X, Yu Z, Song S, Bian H, Tian M, Qin C, Qi J, Zhu Q
BMC medicine 2021 Oct 15;19(1):247
BMC medicine 2021 Oct 15;19(1):247
SMAD2 regulates testicular development and testosterone synthesis in Hu sheep.
Yang H, Wan Z, Jin Y, Wang F, Zhang Y
Theriogenology 2021 Oct 15;174:139-148
Theriogenology 2021 Oct 15;174:139-148
Astaxanthin attenuates contrast-induced acute kidney injury in rats via ROS/NLRP3 inflammasome.
Song L, Yao S, Zheng D, Xuan Y, Li W
International urology and nephrology 2021 Oct 15;
International urology and nephrology 2021 Oct 15;
The FOXM1/RNF26/p57 axis regulates the cell cycle to promote the aggressiveness of bladder cancer.
Yi L, Wang H, Li W, Ye K, Xiong W, Yu H, Jin X
Cell death & disease 2021 Oct 14;12(10):944
Cell death & disease 2021 Oct 14;12(10):944
Human m6A-mRNA and lncRNA epitranscriptomic microarray reveal function of RNA methylation in hemoglobin H-constant spring disease.
Ruan H, Yang F, Deng L, Yang D, Zhang X, Li X, Pang L
Scientific reports 2021 Oct 14;11(1):20478
Scientific reports 2021 Oct 14;11(1):20478
DLEU1 promotes oral squamous cell carcinoma progression by activating interferon-stimulated genes.
Hatanaka Y, Niinuma T, Kitajima H, Nishiyama K, Maruyama R, Ishiguro K, Toyota M, Yamamoto E, Kai M, Yorozu A, Sekiguchi S, Ogi K, Dehari H, Idogawa M, Sasaki Y, Tokino T, Miyazaki A, Suzuki H
Scientific reports 2021 Oct 14;11(1):20438
Scientific reports 2021 Oct 14;11(1):20438
17β-Estradiol Enhances Porcine Meiosis Resumption from Autophagy-Induced Gap Junction Intercellular Communications and Connexin 43 Phosphorylation via the MEK/ERK Signaling Pathway.
Duan J, Chen H, Li Y, Xu D, Li X, Zhang Z, Cheng J, Yang L, Li Q
Journal of agricultural and food chemistry 2021 Oct 13;69(40):11847-11855
Journal of agricultural and food chemistry 2021 Oct 13;69(40):11847-11855
The interaction of S100A16 and GRP78 actives endoplasmic reticulum stress-mediated through the IRE1α/XBP1 pathway in renal tubulointerstitial fibrosis.
Jin R, Zhao A, Han S, Zhang D, Sun H, Li M, Su D, Liang X
Cell death & disease 2021 Oct 13;12(10):942
Cell death & disease 2021 Oct 13;12(10):942
MINDY1 promotes breast cancer cell proliferation by stabilizing estrogen receptor α.
Tang J, Luo Y, Long G, Zhou L
Cell death & disease 2021 Oct 13;12(10):937
Cell death & disease 2021 Oct 13;12(10):937
Phase separation of Nur77 mediates celastrol-induced mitophagy by promoting the liquidity of p62/SQSTM1 condensates.
Peng SZ, Chen XH, Chen SJ, Zhang J, Wang CY, Liu WR, Zhang D, Su Y, Zhang XK
Nature communications 2021 Oct 13;12(1):5989
Nature communications 2021 Oct 13;12(1):5989
BRCA2 associates with MCM10 to suppress PRIMPOL-mediated repriming and single-stranded gap formation after DNA damage.
Kang Z, Fu P, Alcivar AL, Fu H, Redon C, Foo TK, Zuo Y, Ye C, Baxley R, Madireddy A, Buisson R, Bielinsky AK, Zou L, Shen Z, Aladjem MI, Xia B
Nature communications 2021 Oct 13;12(1):5966
Nature communications 2021 Oct 13;12(1):5966
Attenuation of Activated eIF2α Signaling by ISRIB Treatment After Spinal Cord Injury Improves Locomotor Function.
Chang L, Liu X, Chen J, Liu H, Wang G, Wang G, Liao X, Shen X
Journal of molecular neuroscience : MN 2021 Oct 13;
Journal of molecular neuroscience : MN 2021 Oct 13;
Ordered assembly of the cytosolic RNA-sensing MDA5-MAVS signaling complex via binding to unanchored K63-linked poly-ubiquitin chains.
Song B, Chen Y, Liu X, Yuan F, Tan EYJ, Lei Y, Song N, Han Y, Pascal BD, Griffin PR, Luo C, Wu B, Luo D, Zheng J
Immunity 2021 Oct 12;54(10):2218-2230.e5
Immunity 2021 Oct 12;54(10):2218-2230.e5
Blockade of T helper 17 cell function ameliorates recurrent Clostridioides difficile infection in mice.
Wang S, Deng W, Li F, Chen YE, Wang PU
Acta biochimica et biophysica Sinica 2021 Oct 12;53(10):1290-1299
Acta biochimica et biophysica Sinica 2021 Oct 12;53(10):1290-1299
Analyzing the whole-transcriptome profiles of ncRNAs and predicting the competing endogenous RNA networks in cervical cancer cell lines with cisplatin resistance.
Lv H, Jin S, Zou B, Liang Y, Xie J, Wu S
Cancer cell international 2021 Oct 12;21(1):532
Cancer cell international 2021 Oct 12;21(1):532
FAM83A promotes proliferation and metastasis via Wnt/β-catenin signaling in head neck squamous cell carcinoma.
Ji H, Song H, Wang Z, Jiao P, Xu J, Li X, Du H, Wu H, Zhong Y
Journal of translational medicine 2021 Oct 12;19(1):423
Journal of translational medicine 2021 Oct 12;19(1):423
MiR-20a-5p overexpression prevented diabetic cardiomyopathy via inhibition of cardiomyocyte apoptosis, hypertrophy, fibrosis and JNK/NF-κB signalling pathway.
Liu X, Guo B, Zhang W, Ma B, Li Y
Journal of biochemistry 2021 Oct 12;170(3):349-362
Journal of biochemistry 2021 Oct 12;170(3):349-362
Vezatin regulates seizures by controlling AMPAR-mediated synaptic activity.
Wang Y, Yuan J, Yu X, Liu X, Tan C, Chen Y, Xu T
Cell death & disease 2021 Oct 12;12(10):936
Cell death & disease 2021 Oct 12;12(10):936
Inactivation of the CIC-DUX4 oncogene through P300/CBP inhibition, a therapeutic approach for CIC-DUX4 sarcoma.
Bosnakovski D, Ener ET, Cooper MS, Gearhart MD, Knights KA, Xu NC, Palumbo CA, Toso EA, Marsh GP, Maple HJ, Kyba M
Oncogenesis 2021 Oct 12;10(10):68
Oncogenesis 2021 Oct 12;10(10):68
ZFC3H1 prevents RNA trafficking into nuclear speckles through condensation.
Wang Y, Fan J, Wang J, Zhu Y, Xu L, Tong D, Cheng H
Nucleic acids research 2021 Oct 11;49(18):10630-10643
Nucleic acids research 2021 Oct 11;49(18):10630-10643
PCYT2 synthesizes CDP-glycerol in mammals and reduced PCYT2 enhances the expression of functionally glycosylated α-dystroglycan.
Imae R, Manya H, Tsumoto H, Miura Y, Endo T
Journal of biochemistry 2021 Oct 11;170(2):183-194
Journal of biochemistry 2021 Oct 11;170(2):183-194
Integrative epigenomic and high-throughput functional enhancer profiling reveals determinants of enhancer heterogeneity in gastric cancer.
Sheng T, Ho SWT, Ooi WF, Xu C, Xing M, Padmanabhan N, Huang KK, Ma L, Ray M, Guo YA, Sim NL, Anene-Nzelu CG, Chang MM, Razavi-Mohseni M, Beer MA, Foo RSY, Sundar R, Chan YH, Tan ALK, Ong X, Skanderup AJ, White KP, Jha S, Tan P
Genome medicine 2021 Oct 11;13(1):158
Genome medicine 2021 Oct 11;13(1):158
Posttranscriptional inhibition of γ-adducin promotes the proliferation and migration of osteosarcoma cells.
Suo Z, Ma X, Ding Y, Zhou Y, Duan X, Fei L, Song J, Ding H
Tumori 2021 Oct 11;:3008916211050687
Tumori 2021 Oct 11;:3008916211050687
Cigarette smoking induces aberrant N6-methyladenosine of DAPK2 to promote non-small cell lung cancer progression by activating NF-κB pathway.
Jin M, Li G, Liu W, Wu X, Zhu J, Zhao D, Zeng Z, Xiong M, Song Y, He X, Zhang Q, Hu K
Cancer letters 2021 Oct 10;518:214-229
Cancer letters 2021 Oct 10;518:214-229
Autophagy-dependent ferroptosis contributes to cisplatin-induced hearing loss.
Jian B, Pang J, Xiong H, Zhang W, Zhan T, Su Z, Lin H, Zhang H, He W, Zheng Y
Toxicology letters 2021 Oct 10;350:249-260
Toxicology letters 2021 Oct 10;350:249-260
Cold-inducible RNA-binding protein regulates cyclin B1 against spermatogenesis arrest caused by heat stress.
Liu H, Xu C, Bao M, Huang J, Zou L, Fan X, Zhu C, Xia W
Andrology 2021 Oct 10;
Andrology 2021 Oct 10;
Hsa_circ_0011385 knockdown represses cell proliferation in hepatocellular carcinoma.
Ni C, Yang S, Ji Y, Duan Y, Yang W, Yang X, Li M, Xie J, Zhang C, Lu Y, Lu H
Cell death discovery 2021 Oct 1;7(1):270
Cell death discovery 2021 Oct 1;7(1):270
AGTR1 blocker attenuates activation of Tenon's capsule fibroblasts after glaucoma filtration surgery via the NF-κB signaling pathway.
Wang L, Li H, Zhang W, Ren M, Shao M, Wang J
Experimental cell research 2021 Oct 1;407(1):112786
Experimental cell research 2021 Oct 1;407(1):112786
Diabetic ferroptosis plays an important role in triggering on inflammation in diabetic wound.
Li S, Li Y, Wu Z, Wu Z, Fang H
American journal of physiology. Endocrinology and metabolism 2021 Oct 1;321(4):E509-E520
American journal of physiology. Endocrinology and metabolism 2021 Oct 1;321(4):E509-E520
Relationships between di-(2-ethylhexyl) phthalate exposure and lipid metabolism in adolescents: Human data and experimental rat model analyses.
Ding S, Qi W, Xu Q, Zhao T, Li X, Yin J, Zhang R, Huo C, Zhou L, Ye L
Environmental pollution (Barking, Essex : 1987) 2021 Oct 1;286:117570
Environmental pollution (Barking, Essex : 1987) 2021 Oct 1;286:117570
Circ-RNF13, as an oncogene, regulates malignant progression of HBV-associated hepatocellular carcinoma cells and HBV infection through ceRNA pathway of circ-RNF13/miR-424-5p/TGIF2.
Chen Y, Li S, Wei Y, Xu Z, Wu X
Bosnian journal of basic medical sciences 2021 Oct 1;21(5):555-568
Bosnian journal of basic medical sciences 2021 Oct 1;21(5):555-568
Flow cytometry allows rapid detection of protein aggregates in cellular and zebrafish models of spinocerebellar ataxia 3.
Robinson KJ, Tym MC, Hogan A, Watchon M, Yuan KC, Plenderleith SK, Don EK, Laird AS
Disease models & mechanisms 2021 Oct 1;14(10)
Disease models & mechanisms 2021 Oct 1;14(10)
Crosstalk Between RPE Cells and Choroidal Endothelial Cells via the ANXA1/FPR2/SHP2/NLRP3 Inflammasome/Pyroptosis Axis Promotes Choroidal Neovascularization.
Zhu M, Wang Y, Zhu L, Du S, Wang Z, Zhang Y, Guo Y, Tu Y, Song E
Inflammation 2021 Oct 1;
Inflammation 2021 Oct 1;
Elevated β-secretase 1 expression mediates CD4+ T cell dysfunction via PGE2 signalling in Alzheimer's disease.
Dai L, Wang Q, Lv X, Gao F, Chen Z, Shen Y
Brain, behavior, and immunity 2021 Nov;98:337-348
Brain, behavior, and immunity 2021 Nov;98:337-348
Yiqi-Huoxue granule promotes angiogenesis of ischemic myocardium through miR-126/PI3K/Akt axis in endothelial cells.
Gao H, Peng C, Wu L, Gao S, Wang Z, Dai L, Wu H
Phytomedicine : international journal of phytotherapy and phytopharmacology 2021 Nov;92:153713
Phytomedicine : international journal of phytotherapy and phytopharmacology 2021 Nov;92:153713
Switch receptor T3/28 improves long-term persistence and antitumor efficacy of CAR-T cells.
Zhao S, Wang C, Lu P, Lou Y, Liu H, Wang T, Yang S, Bao Z, Han L, Liang X, Ma C, Gao L
Journal for immunotherapy of cancer 2021 Nov;9(12)
Journal for immunotherapy of cancer 2021 Nov;9(12)
Circular RNA circZFPM2 promotes epithelial-mesenchymal transition in endometriosis by regulating miR-205-5p/ZEB1 signalling pathway.
Wang D, Cui L, Yang Q, Wang J
Cellular signalling 2021 Nov;87:110145
Cellular signalling 2021 Nov;87:110145
Decreased phosphorylation facilitates the degradation of the endogenous protective molecule c-Ski in vascular smooth muscle cells.
He W, Chen Z, Li H, Wu W, He P, Zhong D, Jiang Y, Cheng W, Xu Z, Li J
Cellular signalling 2021 Nov;87:110116
Cellular signalling 2021 Nov;87:110116
Neuroprotective effect of Na+ /H+ exchangers isoform-1 inactivation against 6-hydroxydopamine-induced mitochondrial dysfunction and neuronal apoptosis in Parkinson's disease models.
Xing R, Liu X, Tian B, Cheng Y, Li L
Drug development research 2021 Nov;82(7):969-979
Drug development research 2021 Nov;82(7):969-979
Long non-coding RNA HOXA-AS3 facilitates the malignancy in colorectal cancer by miR-4319/SPNS2 axis.
Jiang Y, Yu XY, Sun HX, Gu XY, Geng JS
Journal of physiology and biochemistry 2021 Nov;77(4):653-666
Journal of physiology and biochemistry 2021 Nov;77(4):653-666
Knockdown of ST6Gal-I expression in human hepatocellular carcinoma cells inhibits their exosome-mediated proliferation- and migration-promoting effects.
Wang L, Chen X, Wang L, Wang S, Li W, Liu Y, Zhang J
IUBMB life 2021 Nov;73(11):1378-1391
IUBMB life 2021 Nov;73(11):1378-1391
SARS-CoV-2 B.1.617.2 Delta variant replication and immune evasion.
Mlcochova P, Kemp SA, Dhar MS, Papa G, Meng B, Ferreira IATM, Datir R, Collier DA, Albecka A, Singh S, Pandey R, Brown J, Zhou J, Goonawardane N, Mishra S, Whittaker C, Mellan T, Marwal R, Datta M, Sengupta S, Ponnusamy K, Radhakrishnan VS, Abdullahi A, Charles O, Chattopadhyay P, Devi P, Caputo D, Peacock T, Wattal C, Goel N, Satwik A, Vaishya R, Agarwal M, Indian SARS-CoV-2 Genomics Consortium (INSACOG)., Genotype to Phenotype Japan (G2P-Japan) Consortium., CITIID-NIHR BioResource COVID-19 Collaboration., Mavousian A, Lee JH, Bassi J, Silacci-Fegni C, Saliba C, Pinto D, Irie T, Yoshida I, Hamilton WL, Sato K, Bhatt S, Flaxman S, James LC, Corti D, Piccoli L, Barclay WS, Rakshit P, Agrawal A, Gupta RK
Nature 2021 Nov;599(7883):114-119
Nature 2021 Nov;599(7883):114-119
miR-221/222 suppression induced by activation of the cAMP/PKA/CREB1 pathway is required for cAMP-induced bidirectional differentiation of glioma cells.
Liu Q, Tian R, Yu P, Shu M
FEBS letters 2021 Nov;595(22):2829-2843
FEBS letters 2021 Nov;595(22):2829-2843
Effect of mifepristone and lithospermum combination regimen on medical abortion in early pregnancy rats.
Yu Q, Hu S, Hu S
The journal of obstetrics and gynaecology research 2021 Nov;47(11):3789-3796
The journal of obstetrics and gynaecology research 2021 Nov;47(11):3789-3796
Dihydroartemisinin triggers ferroptosis in primary liver cancer cells by promoting and unfolded protein response‑induced upregulation of CHAC1 expression.
Wang Z, Li M, Liu Y, Qiao Z, Bai T, Yang L, Liu B
Oncology reports 2021 Nov;46(5)
Oncology reports 2021 Nov;46(5)
MiR-214-3p plays a protective role in diabetic neuropathic rats by regulating Nav1.3 and TLR4.
Pang B, Qiao L, Wang S, Guo X, Xie Y, Han L
Cell biology international 2021 Nov;45(11):2294-2303
Cell biology international 2021 Nov;45(11):2294-2303
Silencing ACTG1 Expression Induces Prostate Cancer Epithelial Mesenchymal Transition Through MAPK/ERK Signaling Pathway.
Xiao L, Peng H, Yan M, Chen S
DNA and cell biology 2021 Nov;40(11):1445-1455
DNA and cell biology 2021 Nov;40(11):1445-1455
Selenium-modified calcium phosphate cement can accelerate bone regeneration of osteoporotic bone defect.
Li TL, Tao ZS, Wu XJ, Yang M, Xu HG
Journal of bone and mineral metabolism 2021 Nov;39(6):934-943
Journal of bone and mineral metabolism 2021 Nov;39(6):934-943
Novel WEE2 compound heterozygous mutations identified in patients with fertilization failure or poor fertilization.
Jin J, Tong X, Zhang YL, Yang W, Ma Y, Ren P, Zhou F, Zhang S
Journal of assisted reproduction and genetics 2021 Nov;38(11):2861-2869
Journal of assisted reproduction and genetics 2021 Nov;38(11):2861-2869
Rosamultin from Potentilla anserine L. exhibits nephroprotection and antioxidant activity by regulating the reactive oxygen species/C/EBP homologous protein signaling pathway.
He L, Liu N, Wang K, Zhang L, Li D, Wang Z, Xu G, Liu Y, Xu Q
Phytotherapy research : PTR 2021 Nov;35(11):6343-6358
Phytotherapy research : PTR 2021 Nov;35(11):6343-6358
Icariin attenuates renal fibrosis in chronic kidney disease by inhibiting interleukin-1β/transforming growth factor-β-mediated activation of renal fibroblasts.
Wang M, Wang L, Zhou Y, Feng X, Ye C, Wang C
Phytotherapy research : PTR 2021 Nov;35(11):6204-6215
Phytotherapy research : PTR 2021 Nov;35(11):6204-6215
Cellular hnRNPAB interacts with avian influenza viral protein PB2 and inhibits virus replication potentially by restricting PB2 mRNA nuclear export and PB2 protein level.
Ye H, Bi Z, Fan W, Song S, Yan L
Virus research 2021 Nov;305:198573
Virus research 2021 Nov;305:198573
Environmental Pollutant Benzo[a]pyrene Upregulated Long Non-coding RNA HZ07 Inhibits Trophoblast Cell Migration by Inactivating PI3K/AKT/MMP2 Signaling Pathway in Recurrent Pregnancy Loss.
Ye Y, Jiang S, Du T, Ding M, Hou M, Mi C, Liang T, Zhong H, Xie J, Xu W, Zhang H, Zhao X
Reproductive sciences (Thousand Oaks, Calif.) 2021 Nov;28(11):3085-3093
Reproductive sciences (Thousand Oaks, Calif.) 2021 Nov;28(11):3085-3093
Mapping of pseudouridine residues on cellular and viral transcripts using a novel antibody-based technique.
Martinez Campos C, Tsai K, Courtney DG, Bogerd HP, Holley CL, Cullen BR
RNA (New York, N.Y.) 2021 Nov;27(11):1400-1411
RNA (New York, N.Y.) 2021 Nov;27(11):1400-1411
Japanese encephalitis virus restricts HMGB1 expression to maintain MAPK pathway activation for viral replication.
Xing J, Liang J, Liu S, Huang L, Hu P, Liu L, Liao M, Qi W
Veterinary microbiology 2021 Nov;262:109237
Veterinary microbiology 2021 Nov;262:109237
Drebrin, an actin-binding protein, is required for lens morphogenesis and growth.
Karnam S, Maddala R, Stiber JA, Rao PV
Developmental dynamics : an official publication of the American Association of Anatomists 2021 Nov;250(11):1600-1617
Developmental dynamics : an official publication of the American Association of Anatomists 2021 Nov;250(11):1600-1617
SC66 inhibits the proliferation and induces apoptosis of human bladder cancer cells by targeting the AKT/β-catenin pathway.
Chen W, Zhao S, Yu W, Rao T, Ruan Y, Zhu S, Xia Y, Song H, Cheng F
Journal of cellular and molecular medicine 2021 Nov;25(22):10684-10697
Journal of cellular and molecular medicine 2021 Nov;25(22):10684-10697
Casein Kinase II exacerbates rheumatoid arthritis via promoting Th1 and Th17 cell inflammatory responses.
Ye H, Fu D, Fang X, Xie Y, Zheng X, Fan W, Hu F, Li Z
Expert opinion on therapeutic targets 2021 Nov;25(11):1017-1024
Expert opinion on therapeutic targets 2021 Nov;25(11):1017-1024
miR‑486‑5p suppresses gastric cancer cell growth and migration through downregulation of fibroblast growth factor 9.
Wei W, Liu C, Yao R, Tan Q, Wang Q, Tian H
Molecular medicine reports 2021 Nov;24(5)
Molecular medicine reports 2021 Nov;24(5)
miR-106b-5p upregulation is associated with microglial activation and inflammation in the mouse hippocampus following status epilepticus.
Yu T, Fu H, Sun JJ, Ding DR, Wang H
Experimental brain research 2021 Nov;239(11):3315-3325
Experimental brain research 2021 Nov;239(11):3315-3325
In vivo assessment of molybdenum and cadmium co-induce nephrotoxicity via NLRP3/Caspase-1-mediated pyroptosis in ducks.
Zhang C, Wang X, Nie G, Wei Z, Pi S, Wang C, Yang F, Hu R, Xing C, Hu G
Journal of inorganic biochemistry 2021 Nov;224:111584
Journal of inorganic biochemistry 2021 Nov;224:111584
Inhibition of Dishevelled-2 suppresses the biological behavior of pancreatic cancer by downregulating Wnt/β-catenin signaling.
Hu W, Li M, Wu J, Chen H, Zhao T, Zhang C, Wang Z
Oncology letters 2021 Nov;22(5):769
Oncology letters 2021 Nov;22(5):769
An integrated RNA-Seq and network study reveals that valproate inhibited progesterone production in human granulosa cells.
Li S, Qi J, Sun Y, Gao X, Ma J, Zhao S
The Journal of steroid biochemistry and molecular biology 2021 Nov;214:105991
The Journal of steroid biochemistry and molecular biology 2021 Nov;214:105991
ML-SA1 and SN-2 inhibit endocytosed viruses through regulating TRPML channel expression and activity.
Xia Z, Ren Y, Li S, Xu J, Wu Y, Cao Z
Antiviral research 2021 Nov;195:105193
Antiviral research 2021 Nov;195:105193
Involvement of REV-ERBα dysregulation and ferroptosis in aristolochic acid I-induced renal injury.
Wang Y, Wang Z, Wu Z, Chen M, Dong D, Yu P, Lu D, Wu B
Biochemical pharmacology 2021 Nov;193:114807
Biochemical pharmacology 2021 Nov;193:114807
NEDD4 triggers FOXA1 ubiquitination and promotes colon cancer progression under microRNA-340-5p suppression and ATF1 upregulation.
Yue M, Yun Z, Li S, Yan G, Kang Z
RNA biology 2021 Nov;18(11):1981-1995
RNA biology 2021 Nov;18(11):1981-1995
Chitotriosidase attenuates brain inflammation via HDAC3/NF-κB pathway in D-galactose and aluminum-induced rat model with cognitive impairments.
Yu X, Yu W, Wu L, Yang W, Lü Y
Neuroscience research 2021 Nov;172:73-79
Neuroscience research 2021 Nov;172:73-79
B2M gene expression shapes the immune landscape of lung adenocarcinoma and determines the response to immunotherapy.
Zhao Y, Cao Y, Chen Y, Wu L, Hang H, Jiang C, Zhou X
Immunology 2021 Nov;164(3):507-523
Immunology 2021 Nov;164(3):507-523
Multifunctional MnO2-based nanoplatform-induced ferroptosis and apoptosis for synergetic chemoradiotherapy.
Li X, Wang Q, Yu S, Zhang M, Liu X, Deng G, Liu Y, Wu S
Nanomedicine (London, England) 2021 Nov;16(26):2343-2361
Nanomedicine (London, England) 2021 Nov;16(26):2343-2361
Fragile X mental retardation protein-regulated proinflammatory cytokine expression in the spinal cord contributes to the pathogenesis of inflammatory pain induced by complete Freund's adjuvant.
Yang Y, Zhao J, Li Y, Li X, Chen X, Feng Z
Journal of neurochemistry 2021 Nov;159(3):512-524
Journal of neurochemistry 2021 Nov;159(3):512-524
Prenatal EGCG exposure-induced heart mass reduction in adult male mice and underlying mechanisms.
Zhang S, Ou K, Huang J, Fang L, Wang C, Wang Q
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2021 Nov;157:112588
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2021 Nov;157:112588
1,3-dichloro-2-propanol induced hepatic lipid accumulation by inhibiting autophagy via AKT/mTOR/FOXO1 pathway in mice.
Fan Y, Lu J, Liu J, Zhang R, Yu Z, Guan S
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2021 Nov;157:112578
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2021 Nov;157:112578
Perfluorooctane sulfonate induces autophagy-dependent lysosomal membrane permeabilization by weakened interaction between tyrosinated alpha-tubulin and spinster 1.
Dong Z, Qiu T, Zhang J, Sha S, Han X, Kang J, Shi X, Sun X, Jiang L, Yang G, Yao X, Ma Y
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2021 Nov;157:112540
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2021 Nov;157:112540
Varied thyroid disrupting effects of perfluorooctanoic acid (PFOA) and its novel alternatives hexafluoropropylene-oxide-dimer-acid (GenX) and ammonium 4,8-dioxa-3H-perfluorononanoate (ADONA) in vitro.
Zhang S, Chen K, Li W, Chai Y, Zhu J, Chu B, Li N, Yan J, Zhang S, Yang Y
Environment international 2021 Nov;156:106745
Environment international 2021 Nov;156:106745
αCaMKII in the lateral amygdala mediates PTSD-Like behaviors and NMDAR-Dependent LTD.
An S, Wang J, Zhang X, Duan Y, Xu Y, Lv J, Wang D, Zhang H, Richter-Levin G, Klavir O, Yu B, Cao X
Neurobiology of stress 2021 Nov;15:100359
Neurobiology of stress 2021 Nov;15:100359
Liraglutide ameliorates diabetes-associated cognitive dysfunction via rescuing autophagic flux.
Zhang M, Yan W, Yu Y, Cheng J, Yi X, Guo T, Liu N, Shang J, Wang Z, Hu H, Chen L
Journal of pharmacological sciences 2021 Nov;147(3):234-244
Journal of pharmacological sciences 2021 Nov;147(3):234-244
Osteopontin improves sensitivity to tyrosine kinase inhibitor in lung adenocarcinoma in vitro by promoting epidermal growth factor receptor phosphorylation.
Wang YJ, Wang QW, Yu DH, Song CK, Guo ZX, Liu XP, Chen C, Yao J, Wang AF, Hu WD
Journal of cancer research and clinical oncology 2021 Nov;147(11):3245-3254
Journal of cancer research and clinical oncology 2021 Nov;147(11):3245-3254
Selenium-enriched Bifidobacterium longum DD98 attenuates irinotecan-induced intestinal and hepatic toxicity in vitro and in vivo.
Zhu H, Lu C, Gao F, Qian Z, Yin Y, Kan S, Chen D
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Nov;143:112192
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Nov;143:112192
Platycodon grandiflorus polysaccharides inhibit Pseudorabies virus replication via downregulating virus-induced autophagy.
Xing Y, Wang L, Xu G, Guo S, Zhang M, Cheng G, Liu Y, Liu J
Research in veterinary science 2021 Nov;140:18-25
Research in veterinary science 2021 Nov;140:18-25
Deficiency in WDFY4 reduces the number of CD8+ T cells via reactive oxygen species-induced apoptosis.
Li Y, Li J, Yuan Q, Bian X, Long F, Duan R, Gao F, Gao S, Wei S, Wang A, Liu A, Li X, Sun W, Liu Q
Molecular immunology 2021 Nov;139:131-138
Molecular immunology 2021 Nov;139:131-138
RIP1-dependent linear and nonlinear recruitments of caspase-8 and RIP3 respectively to necrosome specify distinct cell death outcomes.
Li X, Zhong CQ, Wu R, Xu X, Yang ZH, Cai S, Wu X, Chen X, Yin Z, He Q, Li D, Xu F, Yan Y, Qi H, Xie C, Shuai J, Han J
Protein & cell 2021 Nov;12(11):858-876
Protein & cell 2021 Nov;12(11):858-876
Synthesis and evaluation of 3-(phenylethynyl)-1,1'-biphenyl-2-carboxylate derivatives as new HIF-1 inhibitors.
Wang S, Wang X, Shao Y, Shao K, Wang Y, Guo X, Dong H, Zhao W, Li Y, Li G
Bioorganic chemistry 2021 Nov;116:105298
Bioorganic chemistry 2021 Nov;116:105298
DOC-2/DAB2 interactive protein destabilizes c-Myc to impair the growth and self-renewal of colon tumor-repopulating cells.
Li H, Zhou Y, Wang M, Wang H, Zhang Y, Peng R, Zhang R, Zhang M, Zhang M, Qiu P, Liu L, Zhao Q, Liu J
Cancer science 2021 Nov;112(11):4593-4603
Cancer science 2021 Nov;112(11):4593-4603
HIF2α promotes tumour growth in clear cell renal cell carcinoma by increasing the expression of NUDT1 to reduce oxidative stress.
Shi J, Xiong Z, Wang K, Yuan C, Huang Y, Xiao W, Meng X, Chen Z, Lv Q, Miao D, Liang H, Xu T, Xie K, Yang H, Zhang X
Clinical and translational medicine 2021 Nov;11(11):e592
Clinical and translational medicine 2021 Nov;11(11):e592
Ceruloplasmin overexpression is associated with oncogenic pathways and poorer survival rates in clear-cell renal cell carcinoma.
Zhang Y, Chen Z, Chen JG, Chen XF, Gu DH, Liu ZM, Gao YD, Zheng B
FEBS open bio 2021 Nov;11(11):2988-3004
FEBS open bio 2021 Nov;11(11):2988-3004
LINC00370 modulates miR-222-3p-RGS4 axis to protect against osteoporosis progression.
Li L, Zheng B, Zhang F, Luo X, Li F, Xu T, Zhao H, Shi G, Guo Y, Shi J, Sun J
Archives of gerontology and geriatrics 2021 Nov-Dec;97:104505
Archives of gerontology and geriatrics 2021 Nov-Dec;97:104505
CD38 deficiency up-regulated IL-1β and MCP-1 through TLR4/ERK/NF-κB pathway in sepsis pulmonary injury.
Du Y, Zhang H, Guo Y, Song K, Zeng L, Chen Y, Xie Z, Li R
Microbes and infection 2021 Nov-Dec;23(9-10):104845
Microbes and infection 2021 Nov-Dec;23(9-10):104845
Direct Activation of Endothelial Cells by SARS-CoV-2 Nucleocapsid Protein Is Blocked by Simvastatin.
Qian Y, Lei T, Patel PS, Lee CH, Monaghan-Nichols P, Xin HB, Qiu J, Fu M
Journal of virology 2021 Nov 9;95(23):e0139621
Journal of virology 2021 Nov 9;95(23):e0139621
Discovery of Phenolic Glycoside from Hyssopus cuspidatus Attenuates LPS-Induced Inflammatory Responses by Inhibition of iNOS and COX-2 Expression through Suppression of NF-κB Activation.
Liu X, Su J, Wang G, Zheng L, Wang G, Sun Y, Bao Y, Wang S, Huang Y
International journal of molecular sciences 2021 Nov 9;22(22)
International journal of molecular sciences 2021 Nov 9;22(22)
HSD17B6 downregulation predicts poor prognosis and drives tumor progression via activating Akt signaling pathway in lung adenocarcinoma.
Tian T, Hong F, Wang Z, Hu J, Chen N, Lv L, Yi Q
Cell death discovery 2021 Nov 8;7(1):341
Cell death discovery 2021 Nov 8;7(1):341
High throughput sequencing of whole transcriptome and construct of ceRNA regulatory network in RD cells infected with enterovirus D68.
Si J, Tang X, Xu L, Fu H, Li H, He Y, Bao J, Tang J, Li A, Lu N, Yang C
Virology journal 2021 Nov 7;18(1):216
Virology journal 2021 Nov 7;18(1):216
LPS-induced macrophage HMGB1-loaded extracellular vesicles trigger hepatocyte pyroptosis by activating the NLRP3 inflammasome.
Wang G, Jin S, Huang W, Li Y, Wang J, Ling X, Huang Y, Hu Y, Li C, Meng Y, Li X
Cell death discovery 2021 Nov 6;7(1):337
Cell death discovery 2021 Nov 6;7(1):337
Total glycosides from Eucommia ulmoides seed promoted osteogenic differentiation of adipose-derived mesenchymal stem cells and bone formation in ovariectomized rats through regulating Notch signaling pathway.
Zhou YH, Xie Q
Journal of orthopaedic surgery and research 2021 Nov 6;16(1):660
Journal of orthopaedic surgery and research 2021 Nov 6;16(1):660
Erythromycin reduces nasal inflammation by inhibiting immunoglobulin production, attenuating mucus secretion, and modulating cytokine expression.
Yen TT, Jiang RS, Chang CY, Wu CY, Liang KL
Scientific reports 2021 Nov 5;11(1):21737
Scientific reports 2021 Nov 5;11(1):21737
FAK regulates cardiomyocyte mitochondrial fission and function through Drp1.
Chang YW, Song ZH, Chen CC
The FEBS journal 2021 Nov 5;
The FEBS journal 2021 Nov 5;
Follicle-stimulating hormone regulates glycolysis of water buffalo follicular granulosa cells through AMPK/SIRT1 signalling pathway.
Pan Y, Zhu J, Lv Q, Shi D, Yang S, Xing Q, Zhang R, Cheng J, Deng Y
Reproduction in domestic animals = Zuchthygiene 2021 Nov 5;
Reproduction in domestic animals = Zuchthygiene 2021 Nov 5;
Increased expression of TAZ and associated upregulation of PD-L1 in cervical cancer.
Han Y, Liu D, Li L
Cancer cell international 2021 Nov 4;21(1):592
Cancer cell international 2021 Nov 4;21(1):592
N6-methyladenosine modification of CDH1 mRNA promotes PM2.5-induced pulmonary fibrosis via mediating epithelial mesenchymal transition.
Ning J, Du H, Zhang Y, Liu Q, Jiang T, Pang Y, Tian X, Yan L, Niu Y, Zhang R
Toxicological sciences : an official journal of the Society of Toxicology 2021 Nov 4;
Toxicological sciences : an official journal of the Society of Toxicology 2021 Nov 4;
Exogenous adenosine activates A2A adenosine receptor to inhibit RANKL-induced osteoclastogenesis via AP-1 pathway to facilitate bone repair.
Cheng X, Yin C, Deng Y, Li Z
Molecular biology reports 2021 Nov 30;
Molecular biology reports 2021 Nov 30;
GSK-3β manipulates ferroptosis sensitivity by dominating iron homeostasis.
Wang L, Ouyang S, Li B, Wu H, Wang F
Cell death discovery 2021 Nov 3;7(1):334
Cell death discovery 2021 Nov 3;7(1):334
Long non-coding RNA SNHG1 promotes fibroblast-to-myofibroblast transition during the development of pulmonary fibrosis induced by silica particles exposure.
Wu Q, Jiao B, Gui W, Zhang Q, Wang F, Han L
Ecotoxicology and environmental safety 2021 Nov 3;228:112938
Ecotoxicology and environmental safety 2021 Nov 3;228:112938
Effect of Fc-Elabela-21 on renal ischemia/reperfusion injury in mice: Mediation of anti-apoptotic effect via Akt phosphorylation.
Xu F, Wu M, Lu X, Zhang H, Shi L, Xi Y, Zhou H, Wang J, Miao L, Gong DW, Cui W
Peptides 2021 Nov 3;147:170682
Peptides 2021 Nov 3;147:170682
Taxifolin retards the D-galactose-induced aging process through inhibiting Nrf2-mediated oxidative stress and regulating the gut microbiota in mice.
Liu XL, Zhao YC, Zhu HY, Wu M, Zheng YN, Yang M, Cheng ZQ, Ding CB, Liu WC
Food & function 2021 Nov 29;12(23):12142-12158
Food & function 2021 Nov 29;12(23):12142-12158
Cardamonin inhibits osteogenic differentiation of human valve interstitial cells and ameliorates aortic valve calcification via interfering in the NF-κB/NLRP3 inflammasome pathway.
Wang C, Xia Y, Qu L, Liu Y, Liu X, Xu K
Food & function 2021 Nov 29;12(23):11808-11818
Food & function 2021 Nov 29;12(23):11808-11818
MICU3 regulates mitochondrial Ca2+-dependent antioxidant response in skeletal muscle aging.
Yang YF, Yang W, Liao ZY, Wu YX, Fan Z, Guo A, Yu J, Chen QN, Wu JH, Zhou J, Xiao Q
Cell death & disease 2021 Nov 29;12(12):1115
Cell death & disease 2021 Nov 29;12(12):1115
SIRT1/mTOR pathway-mediated autophagy dysregulation promotes Pb-induced hepatic lipid accumulation in HepG2 cells.
Zhao Y, Mao A, Zhang R, Guan S, Lu J
Environmental toxicology 2021 Nov 29;
Environmental toxicology 2021 Nov 29;
Type IIB PKA is highly expressed in β cells and controls cell proliferation via regulating Cyclin D1 expression.
Jiang Y, Zhu L, Wu D, Ni Y, Huang C, Ye H, Yang Y, Liu R, Li Y
The FEBS journal 2021 Nov 28;
The FEBS journal 2021 Nov 28;
LAGE3 promoted cell proliferation, migration, and invasion and inhibited cell apoptosis of hepatocellular carcinoma by facilitating the JNK and ERK signaling pathway.
Xing Y, Liu Y, Qi Z, Liu Z, Wang X, Zhang H
Cellular & molecular biology letters 2021 Nov 27;26(1):49
Cellular & molecular biology letters 2021 Nov 27;26(1):49
NEDD4L-induced ubiquitination mediating UBE2T degradation inhibits progression of lung adenocarcinoma via PI3K-AKT signaling.
Chen Y, Hong H, Wang Q, Li J, Zhang W, Chen T, Li P
Cancer cell international 2021 Nov 27;21(1):631
Cancer cell international 2021 Nov 27;21(1):631
Downregulation of miR-29c promotes muscle wasting by modulating the activity of leukemia inhibitory factor in lung cancer cachexia.
Xie K, Xiong H, Xiao W, Xiong Z, Hu W, Ye J, Xu N, Shi J, Yuan C, Chen Z, Miao D, Zhang X, Yang H
Cancer cell international 2021 Nov 27;21(1):627
Cancer cell international 2021 Nov 27;21(1):627
Bone morphogenetic protein 9 enhances osteogenic and angiogenic responses of human amniotic mesenchymal stem cells cocultured with umbilical vein endothelial cells through the PI3K/AKT/m-TOR signaling pathway.
Liu Z, Li Y, Yang J, Huang J, Luo C, Zhang J, Yan W, Ao Y
Aging 2021 Nov 27;13(22):24829-24849
Aging 2021 Nov 27;13(22):24829-24849
miR-1290 promotes IL-8-mediated vascular endothelial cell adhesion by targeting GSK-3β.
Xu H, Cui Y, Liu X, Zheng X, Liu J, Hu X, Gao F, Hu X, Li M, Wei X, Gao Y, Zhao Y
Molecular biology reports 2021 Nov 27;
Molecular biology reports 2021 Nov 27;
Sesquiterpene Lactones from Sigesbeckia glabrescens Possessing Potent Anti-inflammatory Activity by Directly Binding to IKKα/β.
Gao X, Shen X, Zheng Y, Yang L, Zhang X, Hu G, Jia J, Wang A
Journal of natural products 2021 Nov 26;84(11):2808-2821
Journal of natural products 2021 Nov 26;84(11):2808-2821
Oxidative stress transforms 3CLpro into an insoluble and more active form to promote SARS-CoV-2 replication.
Du L, Xie Y, Zheng K, Wang N, Gao M, Yu T, Cao L, Shao Q, Zou Y, Xia W, Fang Q, Zhao B, Guo D, Peng X, Pan JA
Redox biology 2021 Nov 26;48:102199
Redox biology 2021 Nov 26;48:102199
Reciprocal regulation of LOXL2 and HIF1α drives the Warburg effect to support pancreatic cancer aggressiveness.
Li R, Li H, Zhu L, Zhang X, Liu D, Li Q, Ni B, Hu L, Zhang Z, Zhang Y, Wang X, Jiang SH
Cell death & disease 2021 Nov 26;12(12):1106
Cell death & disease 2021 Nov 26;12(12):1106
Icaritin alleviates docetaxel-induced skin injury by suppressing reactive oxygen species via estrogen receptors.
Zou J, Xu MX, Li F, Wang YH, Li XQ, Yu DJ, Ma YJ, Zhang YY, Sun XD
Thoracic cancer 2021 Nov 26;
Thoracic cancer 2021 Nov 26;
Inhibition of Ras protein activator like 2 produces antitumor effects in gastric cancer via the suppression of YAP1 activation.
Hu Y, Zhang P, Shi Y, Dong X, Wu Y, Dong D, Li E, Fan Y
Environmental toxicology 2021 Nov 26;
Environmental toxicology 2021 Nov 26;
Structure-Based Discovery of Potent CARM1 Inhibitors for Solid Tumor and Cancer Immunology Therapy.
Zhang Z, Guo Z, Xu X, Cao D, Yang H, Li Y, Shi Q, Du Z, Guo X, Wang X, Chen D, Zhang Y, Chen L, Zhou K, Li J, Geng M, Huang X, Xiong B
Journal of medicinal chemistry 2021 Nov 25;64(22):16650-16674
Journal of medicinal chemistry 2021 Nov 25;64(22):16650-16674
The structural basis for the phospholipid remodeling by lysophosphatidylcholine acyltransferase 3.
Zhang Q, Yao D, Rao B, Jian L, Chen Y, Hu K, Xia Y, Li S, Shen Y, Qin A, Zhao J, Zhou L, Lei M, Jiang XC, Cao Y
Nature communications 2021 Nov 25;12(1):6869
Nature communications 2021 Nov 25;12(1):6869
Benzo(a)pyrene induces airway epithelial injury through Wnt5a-mediated non-canonical Wnt-YAP/TAZ signaling.
Fan L, Li W, Ma J, Cheng M, Xie L, Ye Z, Xie Y, Wang B, Yu L, Zhou Y, Chen W
The Science of the total environment 2021 Nov 25;:151965
The Science of the total environment 2021 Nov 25;:151965
Urinary peptidomics reveals proteases involved in idiopathic membranous nephropathy.
Lin B, Liu J, Zhang Y, Wu Y, Chen S, Bai Y, Liu Q, Qin X
BMC genomics 2021 Nov 24;22(1):852
BMC genomics 2021 Nov 24;22(1):852
miR-30b-5p inhibits proliferation, invasion, and migration of papillary thyroid cancer by targeting GALNT7 via the EGFR/PI3K/AKT pathway.
Wang Y, Wang C, Fu Z, Zhang S, Chen J
Cancer cell international 2021 Nov 24;21(1):618
Cancer cell international 2021 Nov 24;21(1):618
4D-quantitative proteomics signature of asthenozoospermia and identification of extracellular matrix protein 1 as a novel biomarker for sperm motility.
Yang J, Liu Q, Yu B, Han B, Yang B
Molecular omics 2021 Nov 24;
Molecular omics 2021 Nov 24;
Naturally occurring UBIAD1 mutations differentially affect menaquinone biosynthesis and vitamin K-dependent carboxylation.
Chen X, Furukawa N, Jin DY, Liu Y, Stafford DW, Williams CM, Suhara Y, Tie JK
The FEBS journal 2021 Nov 23;
The FEBS journal 2021 Nov 23;
METTL3/14 and IL-17 signaling contribute to CEBPA-DT enhanced oral cancer cisplatin resistance.
Qiao X, Zhu L, Song R, Shang C, Guo Y
Oral diseases 2021 Nov 22;
Oral diseases 2021 Nov 22;
circRNAome profiling reveals circFgfr2 regulates myogenesis and muscle regeneration via a feedback loop.
Yan J, Yang Y, Fan X, Liang G, Wang Z, Li J, Wang L, Chen Y, Adetula AA, Tang Y, Li K, Wang D, Tang Z
Journal of cachexia, sarcopenia and muscle 2021 Nov 22;
Journal of cachexia, sarcopenia and muscle 2021 Nov 22;
Extracellular vesicles derived from hypoxia-preconditioned olfactory mucosa mesenchymal stem cells enhance angiogenesis via miR-612.
Ge L, Xun C, Li W, Jin S, Liu Z, Zhuo Y, Duan D, Hu Z, Chen P, Lu M
Journal of nanobiotechnology 2021 Nov 21;19(1):380
Journal of nanobiotechnology 2021 Nov 21;19(1):380
Cadmium attenuates testosterone synthesis by promoting ferroptosis and blocking autophagosome-lysosome fusion.
Zeng L, Zhou J, Wang X, Zhang Y, Wang M, Su P
Free radical biology & medicine 2021 Nov 20;176:176-188
Free radical biology & medicine 2021 Nov 20;176:176-188
IRF3-binding lncRNA-ISIR strengthens interferon production in viral infection and autoinflammation.
Xu J, Wang P, Li Z, Li Z, Han D, Wen M, Zhao Q, Zhang L, Ma Y, Liu W, Jiang M, Zhang X, Cao X
Cell reports 2021 Nov 2;37(5):109926
Cell reports 2021 Nov 2;37(5):109926
Blood-Based Epigenetic Markers of FKBP5 Gene Methylation in Patients With Dilated Cardiomyopathy.
Wada K, Misaka T, Yokokawa T, Kimishima Y, Kaneshiro T, Oikawa M, Yoshihisa A, Takeishi Y
Journal of the American Heart Association 2021 Nov 2;10(21):e021101
Journal of the American Heart Association 2021 Nov 2;10(21):e021101
MiR-15a-3p regulates ferroptosis via targeting glutathione peroxidase GPX4 in colorectal cancer.
Liu L, Yao H, Zhou X, Chen J, Chen G, Shi X, Wu G, Zhou G, He S
Molecular carcinogenesis 2021 Nov 2;
Molecular carcinogenesis 2021 Nov 2;
The Y14-p53 regulatory circuit in megakaryocyte differentiation and thrombocytopenia.
Su CH, Liao WJ, Ke WC, Yang RB, Tarn WY
iScience 2021 Nov 19;24(11):103368
iScience 2021 Nov 19;24(11):103368
Capping protein regulates endosomal trafficking by controlling F-actin density around endocytic vesicles and recruiting RAB5 effectors.
Wang D, Ye Z, Wei W, Yu J, Huang L, Zhang H, Yue J
eLife 2021 Nov 19;10
eLife 2021 Nov 19;10
TBHQ attenuates ferroptosis against 5-fluorouracil-induced intestinal epithelial cell injury and intestinal mucositis via activation of Nrf2.
Deng S, Wu D, Li L, Li J, Xu Y
Cellular & molecular biology letters 2021 Nov 18;26(1):48
Cellular & molecular biology letters 2021 Nov 18;26(1):48
Indole-3-Propionic Acid, a Functional Metabolite of Clostridium sporogenes, Promotes Muscle Tissue Development and Reduces Muscle Cell Inflammation.
Du L, Qi R, Wang J, Liu Z, Wu Z
International journal of molecular sciences 2021 Nov 18;22(22)
International journal of molecular sciences 2021 Nov 18;22(22)
Inhibition of DTYMK significantly restrains the growth of HCC and increases sensitivity to oxaliplatin.
Sun F, Liu Y, Gong T, Pan Q, Xiang T, Zhao J, Tang Y, Chen H, Han Y, Song M, Huang Y, Li H, Chen Y, Yang C, Yang J, Wang Q, Li Y, He J, Weng D, Peng R, Xia J
Cell death & disease 2021 Nov 18;12(12):1093
Cell death & disease 2021 Nov 18;12(12):1093
Identification of proximal SUMO-dependent interactors using SUMO-ID.
Barroso-Gomila O, Trulsson F, Muratore V, Canosa I, Merino-Cacho L, Cortazar AR, Pérez C, Azkargorta M, Iloro I, Carracedo A, Aransay AM, Elortza F, Mayor U, Vertegaal ACO, Barrio R, Sutherland JD
Nature communications 2021 Nov 18;12(1):6671
Nature communications 2021 Nov 18;12(1):6671
Shikonin Induced Program Cell Death through Generation of Reactive Oxygen Species in Renal Cancer Cells.
Tsai MF, Chen SM, Ong AZ, Chung YH, Chen PN, Hsieh YH, Kang YT, Hsu LS
Antioxidants (Basel, Switzerland) 2021 Nov 18;10(11)
Antioxidants (Basel, Switzerland) 2021 Nov 18;10(11)
Downregulation of FAPP2 gene induces cell autophagy and inhibits PI3K/AKT/mTOR pathway in T-cell acute lymphoblastic leukemia.
Yuan T, Wang J, Shi C, Wang Y, Xia B, Xu W, Yang H, Yang Y, Ye MT, Khalid S, Liang Y, Tian C, You MJ, Wang Y
Hematological oncology 2021 Nov 18;
Hematological oncology 2021 Nov 18;
Fluoride Stimulates Anxiety- and Depression-like Behaviors Associated with SIK2-CRTC1 Signaling Dysfunction.
Zhou G, Hu Y, Wang A, Guo M, Du Y, Gong Y, Ding L, Feng Z, Hou X, Xu K, Yu F, Li Z, Ba Y
Journal of agricultural and food chemistry 2021 Nov 17;69(45):13618-13627
Journal of agricultural and food chemistry 2021 Nov 17;69(45):13618-13627
Dendrobium officinale Polysaccharide Alleviates Intestinal Inflammation by Promoting Small Extracellular Vesicle Packaging of miR-433-3p.
Liu H, Liang J, Zhong Y, Xiao G, Efferth T, Georgiev MI, Vargas-De-La-Cruz C, Bajpai VK, Caprioli G, Liu J, Lin J, Wu H, Peng L, Li Y, Ma L, Xiao J, Wang Q
Journal of agricultural and food chemistry 2021 Nov 17;69(45):13510-13523
Journal of agricultural and food chemistry 2021 Nov 17;69(45):13510-13523
Knockdown of circFOXO3 ameliorates cigarette smoke-induced lung injury in mice.
Zhou L, Wu B, Yang J, Wang B, Pan J, Xu D, Du C
Respiratory research 2021 Nov 17;22(1):294
Respiratory research 2021 Nov 17;22(1):294
AKT1/HK2 Axis-mediated Glucose Metabolism: A Novel Therapeutic Target of Sulforaphane in Bladder Cancer.
Huang L, He C, Zheng S, Wu C, Ren M, Shan Y
Molecular nutrition & food research 2021 Nov 17;:e2100738
Molecular nutrition & food research 2021 Nov 17;:e2100738
Aloe-emodin derivative produces anti-atherosclerosis effect by reinforcing AMBRA1-mediated endothelial autophagy.
Tang X, Zhang Y, Liu X, Li X, Zhao H, Cui H, Shi Y, Chen Y, Xu H, Meng Z, Zhao L, Chen H, Wang Z, Zhu M, Lin Y, Yang B, Zhang Y
European journal of pharmacology 2021 Nov 17;:174641
European journal of pharmacology 2021 Nov 17;:174641
Knockout of mafba Causes Inner-Ear Developmental Defects in Zebrafish via the Impairment of Proliferation and Differentiation of Ionocyte Progenitor Cells.
Chen X, Huang Y, Gao P, Lv Y, Jia D, Sun K, Han Y, Hu H, Tang Z, Ren X, Liu M
Biomedicines 2021 Nov 16;9(11)
Biomedicines 2021 Nov 16;9(11)
Inhibition of DCLK1 with DCLK1-IN-1 Suppresses Renal Cell Carcinoma Invasion and Stemness and Promotes Cytotoxic T-Cell-Mediated Anti-Tumor Immunity.
Ding L, Yang Y, Ge Y, Lu Q, Yan Z, Chen X, Du J, Hafizi S, Xu X, Yao J, Liu J, Cao Z, Weygant N
Cancers 2021 Nov 16;13(22)
Cancers 2021 Nov 16;13(22)
Ciliary Type III Adenylyl Cyclase in the VMH Is Crucial for High-Fat Diet-Induced Obesity Mediated by Autophagy.
Yang D, Wu X, Wang W, Zhou Y, Wang Z
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2021 Nov 16;:e2102568
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2021 Nov 16;:e2102568
Smoking-associated upregulation of CBX3 suppresses ARHGAP24 expression to activate Rac1 signaling and promote tumor progression in lung adenocarcinoma.
Jin X, Zhang B, Zhang H, Yu H
Oncogene 2021 Nov 16;
Oncogene 2021 Nov 16;
Remodelling of gut microbiota by Berberine attenuates trimethylamine N-oxide-induced platelet hyperreaction and thrombus formation.
Xie Z, Liu X, Huang X, Liu Q, Yang M, Huang D, Zhao P, Tian J, Wang X, Hou J
European journal of pharmacology 2021 Nov 15;911:174526
European journal of pharmacology 2021 Nov 15;911:174526
STOML2 interacts with PHB through activating MAPK signaling pathway to promote colorectal Cancer proliferation.
Ma W, Chen Y, Xiong W, Li W, Xu Z, Wang Y, Wei Z, Mou T, Wu Z, Cheng M, Zou Y, Zhu Y, Zhou W, Liu F, Geng Y
Journal of experimental & clinical cancer research : CR 2021 Nov 15;40(1):359
Journal of experimental & clinical cancer research : CR 2021 Nov 15;40(1):359
Babao Dan is a robust anti-tumor agent via inhibiting wnt/β-catenin activation and cancer cell stemness.
Xie X, Chen J, Wo D, Ma E, Ning Y, Peng J, Zhu W, Ren DN
Journal of ethnopharmacology 2021 Nov 15;280:114449
Journal of ethnopharmacology 2021 Nov 15;280:114449
(-)-Epigallocatechin-3-gallate mitigates cyclophosphamide-induced intestinal injury by modulating the tight junctions, inflammation and dysbiosis in mice.
Wei R, Liu X, Wang Y, Dong J, Wu F, Mackenzie GG, Su Z
Food & function 2021 Nov 15;12(22):11671-11685
Food & function 2021 Nov 15;12(22):11671-11685
SARS-CoV-2 inhibits induction of the MHC class I pathway by targeting the STAT1-IRF1-NLRC5 axis.
Yoo JS, Sasaki M, Cho SX, Kasuga Y, Zhu B, Ouda R, Orba Y, de Figueiredo P, Sawa H, Kobayashi KS
Nature communications 2021 Nov 15;12(1):6602
Nature communications 2021 Nov 15;12(1):6602
Inhibition of METTL3/m6A/miR126 promotes the migration and invasion of endometrial stromal cells in endometriosis†.
Li X, Xiong W, Long X, Dai X, Peng Y, Xu Y, Zhang Z, Zhang L, Liu Y
Biology of reproduction 2021 Nov 15;105(5):1221-1233
Biology of reproduction 2021 Nov 15;105(5):1221-1233
PRMT1-mediated EZH2 methylation promotes breast cancer cell proliferation and tumorigenesis.
Li Z, Wang D, Chen X, Wang W, Wang P, Hou P, Li M, Chu S, Qiao S, Zheng J, Bai J
Cell death & disease 2021 Nov 13;12(11):1080
Cell death & disease 2021 Nov 13;12(11):1080
TM9SF4 is a novel regulator in lineage commitment of bone marrow mesenchymal stem cells to either osteoblasts or adipocytes.
Yu L, Xie M, Zhang F, Wan C, Yao X
Stem cell research & therapy 2021 Nov 13;12(1):573
Stem cell research & therapy 2021 Nov 13;12(1):573
Discovery of a Dual Tubulin and Poly(ADP-Ribose) Polymerase-1 Inhibitor by Structure-Based Pharmacophore Modeling, Virtual Screening, Molecular Docking, and Biological Evaluation.
Zheng L, Ren R, Sun X, Zou Y, Shi Y, Di B, Niu MM
Journal of medicinal chemistry 2021 Nov 11;64(21):15702-15715
Journal of medicinal chemistry 2021 Nov 11;64(21):15702-15715
The Large GTPase, GBP-2, Regulates Rho Family GTPases to Inhibit Migration and Invadosome Formation in Breast Cancer Cells.
Nyabuto GO, Wilson JP, Heilman SA, Kalb RC, Kopacz JP, Abnave AV, Vestal DJ
Cancers 2021 Nov 11;13(22)
Cancers 2021 Nov 11;13(22)
Deletion of miR-15a inhibited glioma development via targeting Smad7 and inhibiting EMT pathway.
Guo Y, Gao X, An S, Li X, Pan L, Liu H, Liu J, Gao J, Zhao Z, Li G, Han Y, Li Y, Ji Z
Aging 2021 Nov 11;13(21):24339-24348
Aging 2021 Nov 11;13(21):24339-24348
Resveratrol induces proliferation in preosteoblast cell MC3T3-E1 via GATA-1 activating autophagy.
Liu X, Tao J, Yao Y, Yang P, Wang J, Yu M, Hou J, Zhang Y, Gui LI
Acta biochimica et biophysica Sinica 2021 Nov 10;53(11):1495-1504
Acta biochimica et biophysica Sinica 2021 Nov 10;53(11):1495-1504
Lipid droplets are beneficial for rabies virus replication by facilitating viral budding.
Zhao J, Zeng Z, Chen Y, Liu W, Chen H, Fu ZF, Zhao L, Zhou M
Journal of virology 2021 Nov 10;:JVI0147321
Journal of virology 2021 Nov 10;:JVI0147321
Mof acetyltransferase inhibition ameliorates glucose intolerance and islet dysfunction of type 2 diabetes via targeting pancreatic α-cells.
Guo X, Cui C, Song J, He Q, Zang N, Hu H, Wang X, Li D, Wang C, Hou X, Li X, Liang K, Yan F, Chen L
Molecular and cellular endocrinology 2021 Nov 1;537:111425
Molecular and cellular endocrinology 2021 Nov 1;537:111425
Isorhapontigenin (ISO) inhibits EMT through FOXO3A/METTL14/VIMENTIN pathway in bladder cancer cells.
Zhang N, Hua X, Tu H, Li J, Zhang Z, Max C
Cancer letters 2021 Nov 1;520:400-408
Cancer letters 2021 Nov 1;520:400-408
Sodium cantharidate induces Apoptosis in breast cancer cells by regulating energy metabolism via the protein phosphatase 5-p53 axis.
Pang JL, Huang FH, Zhang YH, Wu Y, Ge XM, Li S, Li X
Toxicology and applied pharmacology 2021 Nov 1;430:115726
Toxicology and applied pharmacology 2021 Nov 1;430:115726
Neurotoxicity of a pyrethroid pesticide deltamethrin is associated with the imbalance in proteolytic systems caused by mitophagy activation and proteasome inhibition.
Hirano T, Suzuki N, Ikenaka Y, Hoshi N, Tabuchi Y
Toxicology and applied pharmacology 2021 Nov 1;430:115723
Toxicology and applied pharmacology 2021 Nov 1;430:115723
Comparative analysis of the MyTH4-FERM myosins reveals insights into the determinants of actin track selection in polarized epithelia.
Matoo S, Graves MJ, Acharya P, Choi MS, Storad ZA, Idris RAES, Pickles BK, Arvay TO, Shinder PE, Gerts A, Papish JP, Crawley SW
Molecular biology of the cell 2021 Nov 1;32(21):ar30
Molecular biology of the cell 2021 Nov 1;32(21):ar30
Muse Cells Have Higher Stress Tolerance than Adipose Stem Cells due to the Overexpression of the CCNA2 Gene.
Wang P, Wang S, Ji F, Zhang R
Stem cells and development 2021 Nov 1;30(21):1056-1069
Stem cells and development 2021 Nov 1;30(21):1056-1069
A novel mutation in NF1 gene of patient with Neurofibromatosis type 1: A case report and functional study.
Zhang T, Jia C, Dong Z, Li C, Lu W
Molecular genetics & genomic medicine 2021 May;9(5):e1643
Molecular genetics & genomic medicine 2021 May;9(5):e1643
Trojan Horse Delivery of 4,4'-Dimethoxychalcone for Parkinsonian Neuroprotection.
Zhang W, Chen H, Ding L, Gong J, Zhang M, Guo W, Xu P, Li S, Zhang Y
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2021 May;8(9):2004555
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2021 May;8(9):2004555
Aldehyde Dehydrogenase 2 Mediates Alcohol-Induced Colorectal Cancer Immune Escape through Stabilizing PD-L1 Expression.
Zhang H, Xia Y, Wang F, Luo M, Yang K, Liang S, An S, Wu S, Yang C, Chen D, Xu M, Cai M, To KKW, Fu L
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2021 May;8(10):2003404
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2021 May;8(10):2003404
Elevated type I interferon responses potentiate metabolic dysfunction, inflammation, and accelerated aging in mtDNA mutator mice.
Lei Y, Guerra Martinez C, Torres-Odio S, Bell SL, Birdwell CE, Bryant JD, Tong CW, Watson RO, West LC, West AP
Science advances 2021 May;7(22)
Science advances 2021 May;7(22)
Centrosomal protein FOR20 knockout mice display embryonic lethality and left-right patterning defects.
Xu Z, Liu M, Gao C, Kuang W, Chen X, Liu F, Ge B, Yan X, Zhou T, Xie S
FEBS letters 2021 May;595(10):1462-1472
FEBS letters 2021 May;595(10):1462-1472
The Long Noncoding RNA Hepatocyte Nuclear Factor 4α Antisense RNA 1 Negatively Regulates Cytochrome P450 Enzymes in Huh7 Cells via Histone Modifications.
Wang P, Chen S, Wang Y, Wang X, Yan L, Yang K, Zhong XB, Han S, Zhang L
Drug metabolism and disposition: the biological fate of chemicals 2021 May;49(5):361-368
Drug metabolism and disposition: the biological fate of chemicals 2021 May;49(5):361-368
MiR-195-5p inhibits proliferation and invasion of nerve cells in Hirschsprung disease by targeting GFRA4.
Wang G, Wang H, Zhang L, Guo F, Wu X, Liu Y
Molecular and cellular biochemistry 2021 May;476(5):2061-2073
Molecular and cellular biochemistry 2021 May;476(5):2061-2073
TGIF1 plays a carcinogenic role in esophageal squamous cell carcinoma through the Wnt/β‑catenin and Akt/mTOR signaling pathways.
Kong L, Yu Y, Guan H, Jiang L, Sun F, Li X, Huang W, Li B
International journal of molecular medicine 2021 May;47(5)
International journal of molecular medicine 2021 May;47(5)
LINC01816 promotes the migration, invasion and epithelial‑mesenchymal transition of thyroid carcinoma cells by sponging miR‑34c‑5p and regulating CRABP2 expression levels.
Zhao H, Zhu X, Luo Y, Liu S, Wu W, Zhang L, Zhu J
Oncology reports 2021 May;45(5)
Oncology reports 2021 May;45(5)
Methylation gene KCNC1 is associated with overall survival in patients with seminoma.
Chen S, Xiao L, Peng H, Wang Z, Xie J
Oncology reports 2021 May;45(5)
Oncology reports 2021 May;45(5)
Novel gene-encoded intermolecular FRET sensor for tracking glycosylation of CD147 in living cells.
Lu H, Zhu L, Li W, Hu S, Ge Y, Liu D
Analytical and bioanalytical chemistry 2021 May;413(12):3193-3199
Analytical and bioanalytical chemistry 2021 May;413(12):3193-3199
Relevance of CYP3A5 Expression on the Clinical Outcome of Patients With Renal Cell Carcinoma.
Matsumoto J, Kotera Y, Watari S, Takeuchi K, Ueki H, Koyama T, Wada K, Fujiyoshi M, Nasu Y, Ariyoshi N
Anticancer research 2021 May;41(5):2511-2521
Anticancer research 2021 May;41(5):2511-2521
Acetaldehyde Dehydrogenase 2 regulates HMG-CoA reductase stability and cholesterol synthesis in the liver.
Zhong S, Li L, Liang N, Zhang L, Xu X, Chen S, Yin H
Redox biology 2021 May;41:101919
Redox biology 2021 May;41:101919
Long non-coding RNA SMASR inhibits the EMT by negatively regulating TGF-β/Smad signaling pathway in lung cancer.
Xu L, Liu W, Li T, Hu Y, Wang Y, Huang L, Wang Y, Shao S, Liu X, Zhan Q
Oncogene 2021 May;40(20):3578-3592
Oncogene 2021 May;40(20):3578-3592
Antiangiogenic effect of arsenic trioxide in HUVECs by FoxO3a-regulated autophagy.
Sun Z, Cao Y, Xing Y, Wu M, Shao X, Huang Q, Bai L, Wang L, Zhao Y, Wu Y
Journal of biochemical and molecular toxicology 2021 May;35(5):e22728
Journal of biochemical and molecular toxicology 2021 May;35(5):e22728
Glucose-dependent insulinotropic polypeptide modifies adipose plasticity and promotes beige adipogenesis of human omental adipose-derived stem cells.
Chen X, He X, Guo Y, Liu L, Li H, Tan J, Feng W, Guan H, Cao X, Xiao H, Li Y
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 May;35(5):e21534
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 May;35(5):e21534
L-leucine promotes axonal outgrowth and regeneration via mTOR activation.
Ma C, Teng L, Lin G, Guo B, Zhuo R, Qian X, Guan T, Wu R, Liu Y, Liu M
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 May;35(5):e21526
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 May;35(5):e21526
TUFM is involved in Alzheimer's disease-like pathologies that are associated with ROS.
Zhong BR, Zhou GF, Song L, Wen QX, Deng XJ, Ma YL, Hu LT, Chen GJ
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 May;35(5):e21445
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 May;35(5):e21445
BALB/c mice infected with Angiostrongylus cantonensis: A new model for demyelination in the brain.
Xiong H, Zhou Z, Wu Z, Feng Y, Xie F
Anatomical record (Hoboken, N.J. : 2007) 2021 May;304(5):1084-1093
Anatomical record (Hoboken, N.J. : 2007) 2021 May;304(5):1084-1093
Porcine TRIM21 RING-finger E3 ubiquitin ligase is essential for anti-PRRSV activity.
Wei Y, Zeng S, Zou C, Zhang H, Peng O, Xue C, Cao Y
Veterinary microbiology 2021 May;256:109043
Veterinary microbiology 2021 May;256:109043
RAGE: A potential therapeutic target during FGF1 treatment of diabetes-mediated liver injury.
Zheng P, Tang Z, Xiong J, Wang B, Xu J, Chen L, Cai S, Wu C, Ye L, Xu K, Chen Z, Wu Y, Xiao J
Journal of cellular and molecular medicine 2021 May;25(10):4776-4785
Journal of cellular and molecular medicine 2021 May;25(10):4776-4785
Zebrafish hhatla is involved in cardiac hypertrophy.
Shi X, Zhang Y, Gong Y, Chen M, Brand-Arzamendi K, Liu X, Wen XY
Journal of cellular physiology 2021 May;236(5):3700-3709
Journal of cellular physiology 2021 May;236(5):3700-3709
Podocyte apoptosis in diabetic nephropathy by BASP1 activation of the p53 pathway via WT1.
Zhang Y, Xu C, Ye Q, Tong L, Jiang H, Zhu X, Huang L, Lin W, Fu H, Wang J, Persson PB, Lai EY, Mao J
Acta physiologica (Oxford, England) 2021 May;232(1):e13634
Acta physiologica (Oxford, England) 2021 May;232(1):e13634
LIMIT is an immunogenic lncRNA in cancer immunity and immunotherapy.
Li G, Kryczek I, Nam J, Li X, Li S, Li J, Wei S, Grove S, Vatan L, Zhou J, Du W, Lin H, Wang T, Subramanian C, Moon JJ, Cieslik M, Cohen M, Zou W
Nature cell biology 2021 May;23(5):526-537
Nature cell biology 2021 May;23(5):526-537
Exosomal microRNA-301a-3p promotes the proliferation and invasion of nasopharyngeal carcinoma cells by targeting BTG1 mRNA.
Cheng Q, Li Q, Xu L, Jiang H
Molecular medicine reports 2021 May;23(5)
Molecular medicine reports 2021 May;23(5)
Regulatory role of the TLR4/JNK signaling pathway in sepsis‑induced myocardial dysfunction.
Chang C, Hu L, Sun S, Song Y, Liu S, Wang J, Li P
Molecular medicine reports 2021 May;23(5)
Molecular medicine reports 2021 May;23(5)
Protective effects of curcumin against rat intestinal inflammation‑related motility disorders.
Yao Y, Luo R, Xiong S, Zhang C, Zhang Y
Molecular medicine reports 2021 May;23(5)
Molecular medicine reports 2021 May;23(5)
The DpdtbA induced EMT inhibition in gastric cancer cell lines was through ferritinophagy-mediated activation of p53 and PHD2/hif-1α pathway.
Guan D, Li C, Li Y, Li Y, Wang G, Gao F, Li C
Journal of inorganic biochemistry 2021 May;218:111413
Journal of inorganic biochemistry 2021 May;218:111413
Role of vasodilator-stimulated phosphoprotein in RANKL-differentiated murine macrophage RAW264.7 cells: Modulation of NF-κB, c-Fos and NFATc1 transcription factors.
Hu H, Li C, Zhang H, Wu G, Huang Y
Experimental and therapeutic medicine 2021 May;21(5):412
Experimental and therapeutic medicine 2021 May;21(5):412
Synergistic effects of olaparib combined with ERCC1 on the sensitivity of cisplatin in non-small cell lung cancer.
Xie K, Ni X, Lv S, Zhou G, He H
Oncology letters 2021 May;21(5):365
Oncology letters 2021 May;21(5):365
Promoting roles of KLF5 in myocardial infarction in mice involving microRNA-27a suppression and the following GFPT2/TGF-β/Smad2/3 axis activation.
Tian Z, Zhang Y, Lyu X
Cell cycle (Georgetown, Tex.) 2021 May;20(9):874-893
Cell cycle (Georgetown, Tex.) 2021 May;20(9):874-893
Gut-Lung Dysbiosis Accompanied by Diabetes Mellitus Leads to Pulmonary Fibrotic Change through the NF-κB Signaling Pathway.
Wang G, Hu YX, He MY, Xie YH, Su W, Long D, Zhao R, Wang J, Dai C, Li H, Si ZP, Cheng X, Li RM, Li Z, Yang X
The American journal of pathology 2021 May;191(5):838-856
The American journal of pathology 2021 May;191(5):838-856
Integrated transcriptomics and epigenomics reveal chamber-specific and species-specific characteristics of human and mouse hearts.
Gao J, Zheng Y, Li L, Lu M, Chen X, Wang Y, Li Y, Liu X, Gao Y, Mao Y, Zhao P, Zhang J, Tang F, Song L, Wen L, Wang J
PLoS biology 2021 May;19(5):e3001229
PLoS biology 2021 May;19(5):e3001229
Knockdown of the mRNA encoding the ribosomal protein eL38 in mammalian cells causes a substantial reorganization of genomic transcription.
Gopanenko AV, Kolobova AV, Meschaninova MI, Venyaminova AG, Tupikin AE, Kabilov MR, Malygin AA, Karpova GG
Biochimie 2021 May;184:132-142
Biochimie 2021 May;184:132-142
Mitochondrial TXN2 attenuates amyloidogenesis via selective inhibition of BACE1 expression.
Li KY, Xiang XJ, Song L, Chen J, Luo B, Wen QX, Zhong BR, Zhou GF, Deng XJ, Ma YL, Hu LT, Chen GJ
Journal of neurochemistry 2021 May;157(4):1351-1365
Journal of neurochemistry 2021 May;157(4):1351-1365
α-synuclein abnormalities trigger focal tau pathology, spreading to various brain areas in Parkinson disease.
Hadi F, Akrami H, Totonchi M, Barzegar A, Nabavi SM, Shahpasand K
Journal of neurochemistry 2021 May;157(3):727-751
Journal of neurochemistry 2021 May;157(3):727-751
Toxicological and physiological effects of successive exposure to ochratoxin A at food regulatory limits.
Wei W, Liu C, Ke P, Chen X, Zhou T, Xu J, Zhou Y
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2021 May;151:112128
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2021 May;151:112128
Identification of differentially expressed proteins between fused and open sutures in sagittal nonsyndromic craniosynostosis during suture development by quantitative proteomic analysis.
Bala K, Cuellar A, Herren AW, Boyadjiev SA
Proteomics. Clinical applications 2021 May;15(2-3):e2000031
Proteomics. Clinical applications 2021 May;15(2-3):e2000031
Qingjie Fuzheng Granule suppresses lymphangiogenesis in colorectal cancer via the VEGF-C/VEGFR-3 dependent PI3K/AKT pathway.
Huang B, Lu Y, Gui M, Guan J, Lin M, Zhao J, Mao Q, Lin J
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 May;137:111331
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 May;137:111331
The Kidney-Related Effects of Polystyrene Microplastics on Human Kidney Proximal Tubular Epithelial Cells HK-2 and Male C57BL/6 Mice.
Wang YL, Lee YH, Hsu YH, Chiu IJ, Huang CC, Huang CC, Chia ZC, Lee CP, Lin YF, Chiu HW
Environmental health perspectives 2021 May;129(5):57003
Environmental health perspectives 2021 May;129(5):57003
The clinical significance, prognostic value and biological role of lncRNA LINC01793 in oral squamous cell carcinoma.
Yuan SJ, Li SY, Wang YH, Zhang HF, Hua Y, Wang T
Archives of oral biology 2021 May;125:105105
Archives of oral biology 2021 May;125:105105
Tracing production instability in a clonally derived CHO cell line using single-cell transcriptomics.
Tzani I, Herrmann N, Carillo S, Spargo CA, Hagan R, Barron N, Bones J, Shannon Dillmore W, Clarke C
Biotechnology and bioengineering 2021 May;118(5):2016-2030
Biotechnology and bioengineering 2021 May;118(5):2016-2030
The critical role of ZP genes in female infertility characterized by empty follicle syndrome and oocyte degeneration.
Yang P, Chen T, Liu Y, Hou Z, Wu K, Cao Y, Zhang J, Wang Z, Zhao H
Fertility and sterility 2021 May;115(5):1259-1269
Fertility and sterility 2021 May;115(5):1259-1269
SMYD3-PARP16 axis accelerates unfolded protein response and mediates neointima formation.
Long F, Yang D, Wang J, Wang Q, Ni T, Wei G, Zhu Y, Liu X
Acta pharmaceutica Sinica. B 2021 May;11(5):1261-1273
Acta pharmaceutica Sinica. B 2021 May;11(5):1261-1273
miR-140-3p inhibits colorectal cancer progression and its liver metastasis by targeting BCL9 and BCL2.
Liu D, Chen C, Cui M, Zhang H
Cancer medicine 2021 May;10(10):3358-3372
Cancer medicine 2021 May;10(10):3358-3372
The near-infrared dye IR-61 restores erectile function in a streptozotocin-induced diabetes model via mitochondrial protection.
Yue XF, Shen CX, Wang JW, Dai LY, Fang Q, Long L, Zhi Y, Li XR, Wang YW, Shen GF, Liu ZJ, Shi CM, Li WB
Asian journal of andrology 2021 May-Jun;23(3):249-258
Asian journal of andrology 2021 May-Jun;23(3):249-258
G-Protein-coupled Estrogen Receptor 1 Agonist G-1 Perturbs Sunitinib Resistance-related Phosphoproteomic Signatures in Renal Cell Carcinoma.
Chen SK, Wang YC, Lin TY, Wu HJ, Huang CJ, Ku WC
Cancer genomics & proteomics 2021 May-Jun;18(3):207-220
Cancer genomics & proteomics 2021 May-Jun;18(3):207-220
Silencing TAK1 reduces MAPKs-MMP2/9 expression to reduce inflammation-driven neurohistological disruption post spinal cord injury.
Jiang S, Wu Y, Wu S, Ye S, Kong R, Chang J, Xia M, Bao J, Peng X, Hong X, Qian Z, Li H
Cell death discovery 2021 May 8;7(1):96
Cell death discovery 2021 May 8;7(1):96
BCL7C suppresses ovarian cancer growth by inactivating mutant p53.
Huang C, Hao Q, Shi G, Zhou X, Zhang Y
Journal of molecular cell biology 2021 May 7;13(2):141-150
Journal of molecular cell biology 2021 May 7;13(2):141-150
Time-resolved proteomics profiling of the ciliary Hedgehog response.
May EA, Kalocsay M, D'Auriac IG, Schuster PS, Gygi SP, Nachury MV, Mick DU
The Journal of cell biology 2021 May 3;220(5)
The Journal of cell biology 2021 May 3;220(5)
miR-132 mediates cell permeability and migration by targeting occludin in high-glucose -induced ARPE-19 cells.
Wang SS, Liao X, Liu F, Zhang Q, Qiu JJ, Fu SH
Endocrine journal 2021 May 28;68(5):531-541
Endocrine journal 2021 May 28;68(5):531-541
Neocortex- and hippocampus-specific deletion of Gabrg2 causes temperature-dependent seizures in mice.
Li X, Guo S, Xu S, Chen Z, Wang L, Ding J, Huo J, Xiao L, He Z, Jin Z, Wang F, Sun T
Cell death & disease 2021 May 28;12(6):553
Cell death & disease 2021 May 28;12(6):553
Vertebrate cells differentially interpret ciliary and extraciliary cAMP.
Truong ME, Bilekova S, Choksi SP, Li W, Bugaj LJ, Xu K, Reiter JF
Cell 2021 May 27;184(11):2911-2926.e18
Cell 2021 May 27;184(11):2911-2926.e18
Mitocytosis, a migrasome-mediated mitochondrial quality-control process.
Jiao H, Jiang D, Hu X, Du W, Ji L, Yang Y, Li X, Sho T, Wang X, Li Y, Wu YT, Wei YH, Hu X, Yu L
Cell 2021 May 27;184(11):2896-2910.e13
Cell 2021 May 27;184(11):2896-2910.e13
SEC61G promotes breast cancer development and metastasis via modulating glycolysis and is transcriptionally regulated by E2F1.
Ma J, He Z, Zhang H, Zhang W, Gao S, Ni X
Cell death & disease 2021 May 27;12(6):550
Cell death & disease 2021 May 27;12(6):550
Protective Effects of Fucoxanthin on Hydrogen Peroxide-Induced Calcification of Heart Valve Interstitial Cells.
Chiang YF, Tsai CH, Chen HY, Wang KL, Chang HY, Huang YJ, Hong YH, Ali M, Shieh TM, Huang TC, Lin CI, Hsia SM
Marine drugs 2021 May 26;19(6)
Marine drugs 2021 May 26;19(6)
The SUN1-SPDYA interaction plays an essential role in meiosis prophase I.
Chen Y, Wang Y, Chen J, Zuo W, Fan Y, Huang S, Liu Y, Chen G, Li Q, Li J, Wu J, Bian Q, Huang C, Lei M
Nature communications 2021 May 26;12(1):3176
Nature communications 2021 May 26;12(1):3176
STIP1 knockdown suppresses colorectal cancer cell proliferation, migration and invasion by inhibiting STAT3 pathway.
Xia Y, Chen J, Liu G, Huang W, Wei X, Wei Z, He Y
Chemico-biological interactions 2021 May 25;341:109446
Chemico-biological interactions 2021 May 25;341:109446
circ-PTK2 (hsa_circ_0008305) regulates the pathogenic processes of ovarian cancer via miR-639 and FOXC1 regulatory cascade.
Wu SG, Zhou P, Chen JX, Lei J, Hua L, Dong Y, Hu M, Lian CL, Yang LC, Zhou J
Cancer cell international 2021 May 25;21(1):277
Cancer cell international 2021 May 25;21(1):277
Activation of the STAT3 Signaling Pathway by the RNA-Dependent RNA Polymerase Protein of Arenavirus.
Wang Q, Xin Q, Shang W, Wan W, Xiao G, Zhang LK
Viruses 2021 May 25;13(6)
Viruses 2021 May 25;13(6)
OTUD7B stabilizes estrogen receptor α and promotes breast cancer cell proliferation.
Tang J, Wu Z, Tian Z, Chen W, Wu G
Cell death & disease 2021 May 25;12(6):534
Cell death & disease 2021 May 25;12(6):534
Splicing factor SRSF6 mediates pleural fibrosis.
Liang LM, Xiong L, Cheng PP, Chen SJ, Feng X, Zhou YY, Niu Q, Wang M, Chen Q, Song LJ, Yu F, He XL, Xiang F, Wang X, Ye H, Ma WL
JCI insight 2021 May 24;6(10)
JCI insight 2021 May 24;6(10)
The viral restriction factor tetherin/BST2 tethers cytokinetic midbody remnants to the cell surface.
Presle A, Frémont S, Salles A, Commere PH, Sassoon N, Berlioz-Torrent C, Gupta-Rossi N, Echard A
Current biology : CB 2021 May 24;31(10):2203-2213.e5
Current biology : CB 2021 May 24;31(10):2203-2213.e5
Downregulation of CD151 restricts VCAM-1 mediated leukocyte infiltration to reduce neurobiological injuries after experimental stroke.
Gao C, Jia W, Xu W, Wu Q, Wu J
Journal of neuroinflammation 2021 May 22;18(1):118
Journal of neuroinflammation 2021 May 22;18(1):118
miR-338-3p inhibits autophagy in a rat model of allergic rhinitis after PM2.5 exposure through AKT/mTOR signaling by targeting UBE2Q1.
Wang JC, Huang Y, Zhang RX, Han ZJ, Zhou LL, Sun N, Dong WY, Zhuang GS
Biochemical and biophysical research communications 2021 May 21;554:1-6
Biochemical and biophysical research communications 2021 May 21;554:1-6
Long non-coding RNA SNHG14 aggravates LPS-induced acute kidney injury through regulating miR-495-3p/HIPK1.
Yang N, Wang H, Zhang L, Lv J, Niu Z, Liu J, Zhang Z
Acta biochimica et biophysica Sinica 2021 May 21;53(6):719-728
Acta biochimica et biophysica Sinica 2021 May 21;53(6):719-728
SAA1/TLR2 axis directs chemotactic migration of hepatic stellate cells responding to injury.
Getachew A, Abbas N, You K, Yang Z, Hussain M, Huang X, Cheng Z, Tan S, Tao J, Yu X, Chen Y, Yang F, Pan T, Xu Y, Xu G, Zhuang Y, Wu F, Li Y
iScience 2021 May 21;24(5):102483
iScience 2021 May 21;24(5):102483
Amphiphysin I cleavage by asparagine endopeptidase leads to tau hyperphosphorylation and synaptic dysfunction.
Zhang X, Zou L, Meng L, Xiong M, Pan L, Chen G, Zheng Y, Xiong J, Wang Z, Duong DM, Zhang Z, Cao X, Wang T, Tang L, Ye K, Zhang Z
eLife 2021 May 21;10
eLife 2021 May 21;10
LncRNA CD27-AS1 promotes acute myeloid leukemia progression through the miR-224-5p/PBX3 signaling circuit.
Tao Y, Zhang J, Chen L, Liu X, Yao M, Zhang H
Cell death & disease 2021 May 18;12(6):510
Cell death & disease 2021 May 18;12(6):510
Heme cytotoxicity is the consequence of endoplasmic reticulum stress in atherosclerotic plaque progression.
Pethő D, Hendrik Z, Nagy A, Beke L, Patsalos A, Nagy L, Póliska S, Méhes G, Tóth C, Potor L, Eaton JW, Jacob HS, Balla G, Balla J, Gáll T
Scientific reports 2021 May 17;11(1):10435
Scientific reports 2021 May 17;11(1):10435
LncRNA ZNF674-AS1 regulates granulosa cell glycolysis and proliferation by interacting with ALDOA.
Li D, Wang X, Li G, Dang Y, Zhao S, Qin Y
Cell death discovery 2021 May 16;7(1):107
Cell death discovery 2021 May 16;7(1):107
YTHDF1 Promotes Gastric Carcinogenesis by Controlling Translation of FZD7.
Pi J, Wang W, Ji M, Wang X, Wei X, Jin J, Liu T, Qiang J, Qi Z, Li F, Liu Y, Ma Y, Si Y, Huo Y, Gao Y, Chen Y, Dong L, Su R, Chen J, Rao S, Yi P, Yu S, Wang F, Yu J
Cancer research 2021 May 15;81(10):2651-2665
Cancer research 2021 May 15;81(10):2651-2665
BMI1 regulates multiple myeloma-associated macrophage's pro-myeloma functions.
Zhang D, Huang J, Wang F, Ding H, Cui Y, Yang Y, Xu J, Luo H, Gao Y, Pan L, Wu Y, Gong Y, Xie L, Liu Z, Qu Y, Zhang L, Liu W, Zhang W, Zhao S, Yi Q, Niu T, Zheng Y
Cell death & disease 2021 May 15;12(5):495
Cell death & disease 2021 May 15;12(5):495
Asenapine maleate inhibits angiotensin II-induced proliferation and activation of cardiac fibroblasts via the ROS/TGFβ1/MAPK signaling pathway.
Wu HH, Meng TT, Chen JM, Meng FL, Wang SY, Liu RH, Chen JN, Ning B, Li Y, Su GH
Biochemical and biophysical research communications 2021 May 14;553:172-179
Biochemical and biophysical research communications 2021 May 14;553:172-179
Ferritin disorder in the plasma and hippocampus associated with major depressive disorder.
Wang Y, Li Y, Wu Z, Chen Z, Yu H, He Y, Tian Y, Lan T, Bai M, Chen X, Cheng K, Xie P
Biochemical and biophysical research communications 2021 May 14;553:114-118
Biochemical and biophysical research communications 2021 May 14;553:114-118
Hyperactivation of HER2-SHCBP1-PLK1 axis promotes tumor cell mitosis and impairs trastuzumab sensitivity to gastric cancer.
Shi W, Zhang G, Ma Z, Li L, Liu M, Qin L, Yu Z, Zhao L, Liu Y, Zhang X, Qin J, Ye H, Jiang X, Zhou H, Sun H, Jiao Z
Nature communications 2021 May 14;12(1):2812
Nature communications 2021 May 14;12(1):2812
Endothelial genetic deletion of CD147 induces changes in the dual function of the blood-brain barrier and is implicated in Alzheimer's disease.
Wang H, Lv JJ, Zhao Y, Wei HL, Zhang TJ, Yang HJ, Chen ZN, Jiang JL
CNS neuroscience & therapeutics 2021 May 13;
CNS neuroscience & therapeutics 2021 May 13;
Interactions between Autophagy, Proinflammatory Cytokines, and Apoptosis in Neuropathic Pain: Granulocyte Colony Stimulating Factor as a Multipotent Therapy in Rats with Chronic Constriction Injury.
Liao MF, Yeh SR, Lu KT, Hsu JL, Chao PK, Hsu HC, Peng CH, Lee YL, Hung YH, Ro LS
Biomedicines 2021 May 12;9(5)
Biomedicines 2021 May 12;9(5)
Antifungal Activity of Quinofumelin against Fusarium graminearum and Its Inhibitory Effect on DON Biosynthesis.
Xiu Q, Bi L, Xu H, Li T, Zhou Z, Li Z, Wang J, Duan Y, Zhou M
Toxins 2021 May 12;13(5)
Toxins 2021 May 12;13(5)
Zuojin Pill ameliorates chronic atrophic gastritis induced by MNNG through TGF-β1/PI3K/Akt axis.
Tong Y, Wang R, Liu X, Tian M, Wang Y, Cui Y, Zou W, Zhao Y
Journal of ethnopharmacology 2021 May 10;271:113893
Journal of ethnopharmacology 2021 May 10;271:113893
Tryptanthrin Regulates Vascular Smooth Muscle Cell Phenotypic Switching in Atherosclerosis by AMP-Activated Protein Kinase/Acetyl-CoA Carboxylase Signaling Pathway.
Shi X, Zhang Y, Han J, Peng W, Fang Z, Qin Y, Xu X, Lin J, Xiao F, Zhao L, Lin Y
Journal of cardiovascular pharmacology 2021 May 1;77(5):642-649
Journal of cardiovascular pharmacology 2021 May 1;77(5):642-649
LRRC4 functions as a neuron-protective role in experimental autoimmune encephalomyelitis.
Zhang Y, Li D, Zeng Q, Feng J, Fu H, Luo Z, Xiao B, Yang H, Wu M
Molecular medicine (Cambridge, Mass.) 2021 May 1;27(1):44
Molecular medicine (Cambridge, Mass.) 2021 May 1;27(1):44
Psoralidin, a major component of Psoraleae Fructus, induces inflammasome activation and idiosyncratic liver injury.
Wang Y, Xu G, Wang Z, Li R, Zhan X, Liu H, Qin Q, Li W, Wang X, Zhang M, Tang J, Bai Z, Xiao X
International immunopharmacology 2021 Mar;92:107352
International immunopharmacology 2021 Mar;92:107352
Hypoxia enhances the production and antitumor effect of exosomes derived from natural killer cells.
Jiang Y, Jiang H, Wang K, Liu C, Man X, Fu Q
Annals of translational medicine 2021 Mar;9(6):473
Annals of translational medicine 2021 Mar;9(6):473
Arginine methyltransferase PRMT5 negatively regulates cGAS-mediated antiviral immune response.
Ma D, Yang M, Wang Q, Sun C, Shi H, Jing W, Bi Y, Shen X, Ma X, Qin Z, Lin Y, Zhu L, Zhao Y, Cheng Y, Han L
Science advances 2021 Mar;7(13)
Science advances 2021 Mar;7(13)
The cryo-EM structure of an ERAD protein channel formed by tetrameric human Derlin-1.
Rao B, Li S, Yao D, Wang Q, Xia Y, Jia Y, Shen Y, Cao Y
Science advances 2021 Mar;7(10)
Science advances 2021 Mar;7(10)
Decreased miR-214-3p activates NF-κB pathway and aggravates osteoarthritis progression.
Cao Y, Tang S, Nie X, Zhou Z, Ruan G, Han W, Zhu Z, Ding C
EBioMedicine 2021 Mar;65:103283
EBioMedicine 2021 Mar;65:103283
Total flavone extract from Ampelopsis megalophylla induces apoptosis in the MCF‑7 cell line.
Gui C, Zhang C, Xiong X, Huang J, Xi J, Gong L, Huang B, Zhang X
International journal of oncology 2021 Mar;58(3):409-418
International journal of oncology 2021 Mar;58(3):409-418
Biological testing of chitosan-collagen-based porous scaffolds loaded with PLGA/Triamcinolone microspheres for ameliorating endoscopic dissection-related stenosis in oesophagus.
Ni W, Lin S, Bian S, Xiao M, Wang Y, Yang Y, Lu C, Zheng W, Zhou P
Cell proliferation 2021 Mar;54(3):e13004
Cell proliferation 2021 Mar;54(3):e13004
Sirtuin 1 ameliorates defenestration in hepatic sinusoidal endothelial cells during liver fibrosis via inhibiting stress-induced premature senescence.
Luo X, Bai Y, He S, Sun S, Jiang X, Yang Z, Lu D, Wei P, Liang Y, Peng C, Wang Y, Sheng R, Han S, Li X, Zhang B
Cell proliferation 2021 Mar;54(3):e12991
Cell proliferation 2021 Mar;54(3):e12991
miR‑106b‑5p targeting SIX1 inhibits TGF‑β1‑induced pulmonary fibrosis and epithelial‑mesenchymal transition in asthma through regulation of E2F1.
Liu S, Chen X, Zhang S, Wang X, Du X, Chen J, Zhou G
International journal of molecular medicine 2021 Mar;47(3)
International journal of molecular medicine 2021 Mar;47(3)
VSP‑17 suppresses the migration and invasion of triple‑negative breast cancer cells through inhibition of the EMT process via the PPARγ/AMPK signaling pathway.
Xu X, Liu M, Yang Y, Wei C, Zhang X, Song H, Wang Y, Duan X
Oncology reports 2021 Mar;45(3):975-986
Oncology reports 2021 Mar;45(3):975-986
Nucleolar and spindle‑associated protein 1 promotes non‑small cell lung cancer progression and serves as an effector of myocyte enhancer factor 2D.
Ling B, Wei P, Xiao J, Cen B, Wei H, Feng X, Ye G, Li S, Zhang Z, Liang W, Huang S, Huang W
Oncology reports 2021 Mar;45(3):1044-1058
Oncology reports 2021 Mar;45(3):1044-1058
20(S)-ginsenoside Rh2 induces caspase-dependent promyelocytic leukemia-retinoic acid receptor A degradation in NB4 cells via Akt/Bax/caspase9 and TNF-α/caspase8 signaling cascades.
Zhu S, Liu X, Xue M, Li Y, Cai D, Wang S, Zhang L
Journal of ginseng research 2021 Mar;45(2):295-304
Journal of ginseng research 2021 Mar;45(2):295-304
Abnormal cGMP-dependent protein kinase I-mediated decidualization in preeclampsia.
Chen J, Ren W, Lin L, Zeng S, Huang L, Tang J, Bi S, Pan J, Chen D, Du L
Hypertension research : official journal of the Japanese Society of Hypertension 2021 Mar;44(3):318-324
Hypertension research : official journal of the Japanese Society of Hypertension 2021 Mar;44(3):318-324
KLF4 initiates sustained YAP activation to promote renal fibrosis in mice after ischemia-reperfusion kidney injury.
Xu D, Chen PP, Zheng PQ, Yin F, Cheng Q, Zhou ZL, Xie HY, Li JY, Ni JY, Wang YZ, Chen SJ, Zhou L, Wang XX, Liu J, Zhang W, Lu LM
Acta pharmacologica Sinica 2021 Mar;42(3):436-450
Acta pharmacologica Sinica 2021 Mar;42(3):436-450
miR-30a-5p Inhibits Epithelial-to-Mesenchymal Transition by Targeting CDK6 in Nasal Polyps.
Zhang T, Zhou Y, You B, You Y, Yan Y, Zhang J, Pei Y, Zhang W, Chen J
American journal of rhinology & allergy 2021 Mar;35(2):152-163
American journal of rhinology & allergy 2021 Mar;35(2):152-163
Oncogenic AURKA-enhanced N6-methyladenosine modification increases DROSHA mRNA stability to transactivate STC1 in breast cancer stem-like cells.
Peng F, Xu J, Cui B, Liang Q, Zeng S, He B, Zou H, Li M, Zhao H, Meng Y, Chen J, Liu B, Lv S, Chu P, An F, Wang Z, Huang J, Zhan Y, Liao Y, Lu J, Xu L, Zhang J, Sun Z, Li Z, Wang F, Lam EW, Liu Q
Cell research 2021 Mar;31(3):345-361
Cell research 2021 Mar;31(3):345-361
NFAT Overexpression Correlates with CA72-4 and Poor Prognosis of Ovarian Clear-Cell Carcinoma Subtype.
Xin B, Ji KQ, Liu YS, Zhao XD
Reproductive sciences (Thousand Oaks, Calif.) 2021 Mar;28(3):745-756
Reproductive sciences (Thousand Oaks, Calif.) 2021 Mar;28(3):745-756
TRF2 recruits nucleolar protein TCOF1 to coordinate telomere transcription and replication.
Nie X, Xiao D, Ge Y, Xie Y, Zhou H, Zheng T, Li X, Liu H, Huang H, Zhao Y
Cell death and differentiation 2021 Mar;28(3):1062-1075
Cell death and differentiation 2021 Mar;28(3):1062-1075
Histone deacetylase 3 aberration inhibits Klotho transcription and promotes renal fibrosis.
Chen F, Gao Q, Wei A, Chen X, Shi Y, Wang H, Cao W
Cell death and differentiation 2021 Mar;28(3):1001-1012
Cell death and differentiation 2021 Mar;28(3):1001-1012
Chondrocyte ferroptosis contribute to the progression of osteoarthritis.
Yao X, Sun K, Yu S, Luo J, Guo J, Lin J, Wang G, Guo Z, Ye Y, Guo F
Journal of orthopaedic translation 2021 Mar;27:33-43
Journal of orthopaedic translation 2021 Mar;27:33-43
Gambogic acid ameliorates high glucose- and palmitic acid-induced inflammatory response in ARPE-19 cells via activating Nrf2 signaling pathway: ex vivo.
Chen J, Li L, Zhou Y, Zhang J, Chen L
Cell stress & chaperones 2021 Mar;26(2):367-375
Cell stress & chaperones 2021 Mar;26(2):367-375
AIMP3 inhibits cell growth and metastasis of lung adenocarcinoma through activating a miR-96-5p-AIMP3-p53 axis.
Ding L, Fang Y, Li Y, Hu Q, Ai M, Deng K, Huang X, Xin H
Journal of cellular and molecular medicine 2021 Mar;25(6):3019-3030
Journal of cellular and molecular medicine 2021 Mar;25(6):3019-3030
CRKL promotes hepatocarcinoma through enhancing glucose metabolism of cancer cells via activating PI3K/Akt.
Guo C, Gao C, Lv X, Zhao D, Greenaway FT, Hao L, Tian Y, Liu S, Sun MZ
Journal of cellular and molecular medicine 2021 Mar;25(5):2714-2724
Journal of cellular and molecular medicine 2021 Mar;25(5):2714-2724
P53 regulation of osteoblast differentiation is mediated through specific microRNAs.
Shah S, Pendleton E, Couture O, Broachwalla M, Kusper T, Alt LAC, Fay MJ, Chandar N
Biochemistry and biophysics reports 2021 Mar;25:100920
Biochemistry and biophysics reports 2021 Mar;25:100920
SHARPIN stabilizes β-catenin through a linear ubiquitination-independent manner to support gastric tumorigenesis.
Zhang L, Liu Q, Liu KW, Qin ZY, Zhu GX, Shen LT, Zhang N, Liu BY, Che LR, Li JY, Wang T, Wen LZ, Liu KJ, Guo Y, Yin XR, Wang XW, Zhou ZH, Xiao HL, Cui YH, Bian XW, Lan CH, Chen D, Wang B
Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association 2021 Mar;24(2):402-416
Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association 2021 Mar;24(2):402-416
α5-nAChR and survivin: Two potential biological targets in lung adenocarcinoma.
Zhang Y, Sun Y, Jia Y, Zhang Q, Zhu P, Ma X
Journal of cellular physiology 2021 Mar;236(3):1787-1797
Journal of cellular physiology 2021 Mar;236(3):1787-1797
Zenglv Fumai Granule protects cardiomyocytes against hypoxia/reoxygenation-induced apoptosis via inhibiting TRIM28 expression.
Zhang XH, Zhao HY, Wang Y, Di L, Liu XY, Qian F, Liu SR
Molecular medicine reports 2021 Mar;23(3)
Molecular medicine reports 2021 Mar;23(3)
Genetic response to low‑intensity ultrasound on mouse ST2 bone marrow stromal cells.
Tabuchi Y, Hasegawa H, Suzuki N, Furusawa Y, Hirano T, Nagaoka R, Hirayama J, Hoshi N, Mochizuki T
Molecular medicine reports 2021 Mar;23(3)
Molecular medicine reports 2021 Mar;23(3)
Emodin enhances cisplatin sensitivity in non-small cell lung cancer through Pgp downregulation.
Peng S, Wang J, Lu C, Xu Z, Chai JJ, Ke Q, Deng XZ
Oncology letters 2021 Mar;21(3):230
Oncology letters 2021 Mar;21(3):230
Decreased Expression of Heat Shock Protein 47 Is Associated with T-2 Toxin and Low Selenium-Induced Matrix Degradation in Cartilages of Kashin-Beck Disease.
Zhang M, Wang M, Wang H, Zhang Y, Li Z, Feng Y, Liu Y, Liu Y, Liao Y, Wang W, Fang Q, Chen J
Biological trace element research 2021 Mar;199(3):944-954
Biological trace element research 2021 Mar;199(3):944-954
Two loss-of-function ANKRD11 variants in Chinese patients with short stature and a possible molecular pathway.
Zhang T, Yang Y, Yin X, Wang X, Ni J, Dong Z, Li C, Lu W
American journal of medical genetics. Part A 2021 Mar;185(3):710-718
American journal of medical genetics. Part A 2021 Mar;185(3):710-718
Nuciferine protects against folic acid-induced acute kidney injury by inhibiting ferroptosis.
Li D, Liu B, Fan Y, Liu M, Han B, Meng Y, Xu X, Song Z, Liu X, Hao Q, Duan X, Nakai A, Chang Y, Cao P, Tan K
British journal of pharmacology 2021 Mar;178(5):1182-1199
British journal of pharmacology 2021 Mar;178(5):1182-1199
JMJD6 negatively regulates cytosolic RNA induced antiviral signaling by recruiting RNF5 to promote activated IRF3 K48 ubiquitination.
Zhang W, Wang Q, Yang F, Zhu Z, Duan Y, Yang Y, Cao W, Zhang K, Ma J, Liu X, Zheng H
PLoS pathogens 2021 Mar;17(3):e1009366
PLoS pathogens 2021 Mar;17(3):e1009366
CITED4 mediates proliferation, apoptosis and steroidogenesis of Hu sheep granulosa cells in vitro.
Yao X, Ei-Samahy MA, Xiao S, Wang Z, Meng F, Li X, Bao Y, Zhang Y, Wang Z, Fan Y, Wang F
Reproduction (Cambridge, England) 2021 Mar;161(3):255-267
Reproduction (Cambridge, England) 2021 Mar;161(3):255-267
Babao Dan improves neurocognitive function by inhibiting inflammation in clinical minimal hepatic encephalopathy.
Lu B, Wu C, Azami NLB, Xie D, Zhao C, Xu W, Hui D, Chen X, Sun R, Song J, An Y, Li K, Wang H, Ye G, Sun M
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Mar;135:111084
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Mar;135:111084
DZNep attenuates allergic airway inflammation in an ovalbumin-induced murine model.
Li H, Li J, Lu T, Chen D, Xu R, Sun W, Luo X, Li H, Ma R, Wen W
Molecular immunology 2021 Mar;131:60-67
Molecular immunology 2021 Mar;131:60-67
Radiotherapy programs neutrophils to an antitumor phenotype by inducing mesenchymal-epithelial transition.
Liu Q, Hao Y, Du R, Hu D, Xie J, Zhang J, Deng G, Liang N, Tian T, Käsmann L, Rades D, Rim CH, Hu P, Zhang J
Translational lung cancer research 2021 Mar;10(3):1424-1443
Translational lung cancer research 2021 Mar;10(3):1424-1443
Plumbagin, a Biomolecule with (Anti)Osteoclastic Properties.
Sultanli S, Ghumnani S, Ashma R, Kubatzky KF
International journal of molecular sciences 2021 Mar 9;22(5)
International journal of molecular sciences 2021 Mar 9;22(5)
Identification of Overexpressed Genes in Malignant Pleural Mesothelioma.
Morani F, Bisceglia L, Rosini G, Mutti L, Melaiu O, Landi S, Gemignani F
International journal of molecular sciences 2021 Mar 8;22(5)
International journal of molecular sciences 2021 Mar 8;22(5)
Epigenetically modulated miR-1224 suppresses the proliferation of HCC through CREB-mediated activation of YAP signaling pathway.
Yang S, Jiang W, Yang W, Yang C, Yang X, Chen K, Hu Y, Shen G, Lu L, Cheng F, Zhang F, Rao J, Wang X
Molecular therapy. Nucleic acids 2021 Mar 5;23:944-958
Molecular therapy. Nucleic acids 2021 Mar 5;23:944-958
Circular RNA RBPMS inhibits bladder cancer progression via miR-330-3p/RAI2 regulation.
Yang C, Mou Z, Zhang Z, Wu S, Zhou Q, Chen Y, Gong J, Xu C, Ou Y, Chen X, Dai X, Jiang H
Molecular therapy. Nucleic acids 2021 Mar 5;23:872-886
Molecular therapy. Nucleic acids 2021 Mar 5;23:872-886
Long noncoding RNA SMUL suppresses SMURF2 production-mediated muscle atrophy via nonsense-mediated mRNA decay.
Cai B, Li Z, Ma M, Zhang J, Kong S, Abdalla BA, Xu H, Jebessa E, Zhang X, Lawal RA, Nie Q
Molecular therapy. Nucleic acids 2021 Mar 5;23:512-526
Molecular therapy. Nucleic acids 2021 Mar 5;23:512-526
Design, synthesis and pharmacological evaluation of bicyclic and tetracyclic pyridopyrimidinone analogues as new KRASG12C inhibitors.
Xiao X, Lai M, Song Z, Geng M, Ding J, Xie H, Zhang A
European journal of medicinal chemistry 2021 Mar 5;213:113082
European journal of medicinal chemistry 2021 Mar 5;213:113082
miR-98-5p protects against cerebral ischemia/reperfusion injury through anti-apoptosis and anti-oxidative stress in mice.
Yu S, Zhai J, Yu J, Yang Q, Yang J
Journal of biochemistry 2021 Mar 5;169(2):195-206
Journal of biochemistry 2021 Mar 5;169(2):195-206
Hepatic HuR protects against the pathogenesis of non-alcoholic fatty liver disease by targeting PTEN.
Tian M, Wang J, Liu S, Li X, Li J, Yang J, Zhang C, Zhang W
Cell death & disease 2021 Mar 4;12(3):236
Cell death & disease 2021 Mar 4;12(3):236
Normalizing hyperactivity of the Gunn rat with bilirubin-induced neurological disorders via ketanserin.
Miura S, Tsuchie K, Fukushima M, Arauchi R, Tsumori T, Otsuki K, Hayashida M, Hashioka S, Wake R, Miyaoka T, Inagaki M, Oh-Nishi A
Pediatric research 2021 Mar 31;
Pediatric research 2021 Mar 31;
HIF-1/AKT Signaling-Activated PFKFB2 Alleviates Cardiac Dysfunction and Cardiomyocyte Apoptosis in Response to Hypoxia.
Gao J, Feng W, Lv W, Liu W, Fu C
International heart journal 2021 Mar 30;62(2):350-358
International heart journal 2021 Mar 30;62(2):350-358
Involvement of HECTD1 in LPS-induced astrocyte activation via σ-1R-JNK/p38-FOXJ2 axis.
Tang Y, Zhou M, Huang R, Shen L, Yang L, Zhou Z, Ren H, Bai Y
Cell & bioscience 2021 Mar 30;11(1):62
Cell & bioscience 2021 Mar 30;11(1):62
Interaction of NEP with G Protein Pathway Suppressor 2 Facilitates Influenza A Virus Replication by Weakening the Inhibition of GPS2 to RNA Synthesis and Ribonucleoprotein Assembly.
Gong W, He X, Huang K, Zhang Y, Li C, Yang Y, Zou Z, Jin M
Journal of virology 2021 Mar 3;
Journal of virology 2021 Mar 3;
LMNB2 promotes the progression of colorectal cancer by silencing p21 expression.
Dong CH, Jiang T, Yin H, Song H, Zhang Y, Geng H, Shi PC, Xu YX, Gao H, Liu LY, Zhou L, Zhang ZH, Song J
Cell death & disease 2021 Mar 29;12(4):331
Cell death & disease 2021 Mar 29;12(4):331
Let-7i-5p enhances cell proliferation, migration and invasion of ccRCC by targeting HABP4.
Liu Y, Hu X, Hu L, Xu C, Liang X
BMC urology 2021 Mar 28;21(1):49
BMC urology 2021 Mar 28;21(1):49
Parkinson's Disease Causative Mutation in Vps35 Disturbs Tetherin Trafficking to Cell Surfaces and Facilitates Virus Spread.
Ding Y, Li Y, Chhetri G, Peng X, Wu J, Wang Z, Zhao B, Zhao W, Li X
Cells 2021 Mar 28;10(4)
Cells 2021 Mar 28;10(4)
Metabolomics analysis delineates the therapeutic effects of Huangqi decoction and astragalosides on α-naphthylisothiocyanate (ANIT) -induced cholestasis in rats.
Qiu J, Yan J, Liu W, Liu X, Lin J, Du Z, Qi L, Liu J, Xie G, Liu P, Wang X
Journal of ethnopharmacology 2021 Mar 25;268:113658
Journal of ethnopharmacology 2021 Mar 25;268:113658
Crocetin ameliorates chronic restraint stress-induced depression-like behaviors in mice by regulating MEK/ERK pathways and gut microbiota.
Lin S, Li Q, Jiang S, Xu Z, Jiang Y, Liu L, Jiang J, Tong Y, Wang P
Journal of ethnopharmacology 2021 Mar 25;268:113608
Journal of ethnopharmacology 2021 Mar 25;268:113608
NMR-Based Metabolomic Analysis for the Effects of α-Ketoglutarate Supplementation on C2C12 Myoblasts in Different Energy States.
Li Y, Li X, Gao Y, Huang C, Lin D
Molecules (Basel, Switzerland) 2021 Mar 25;26(7)
Molecules (Basel, Switzerland) 2021 Mar 25;26(7)
Membrane-cytoplasm translocation of annexin A4 is involved in the metastasis of colorectal carcinoma.
Peng Y, Zhang Z, Zhang A, Liu C, Sun Y, Peng Z, Liu Y
Aging 2021 Mar 24;13(7):10312-10325
Aging 2021 Mar 24;13(7):10312-10325
Acoustic Droplet Vitrification Method for High-Efficiency Preservation of Rare Cells.
Xia Y, Huang LX, Chen H, Li J, Chen KK, Hu H, Wang FB, Ding Z, Guo SS
ACS applied materials & interfaces 2021 Mar 24;13(11):12950-12959
ACS applied materials & interfaces 2021 Mar 24;13(11):12950-12959
CircRNA RSF1 regulated ox-LDL induced vascular endothelial cells proliferation, apoptosis and inflammation through modulating miR-135b-5p/HDAC1 axis in atherosclerosis.
Zhang X, Lu J, Zhang Q, Luo Q, Liu B
Biological research 2021 Mar 23;54(1):11
Biological research 2021 Mar 23;54(1):11
Tanshinone IIA combined with CsA inhibit myocardial cell apoptosis induced by renal ischemia-reperfusion injury in obese rats.
Tai H, Jiang XL, Lan ZM, Li Y, Kong L, Yao SC, Song N, Lv MJ, Wu J, Yang P, Xiao XS, Yang GL, Kuang JS, Jia LQ
BMC complementary medicine and therapies 2021 Mar 22;21(1):100
BMC complementary medicine and therapies 2021 Mar 22;21(1):100
VPS34 regulates dynamin to determine the endocytosis of mitochondria-targeted zinc oxide nanoparticles in human osteosarcoma cells.
Pan X, He G, Hai B, Liu Y, Bian L, Yong L, Zhang H, Yang C, Du C, Mao T, Ma Y, Jia F, Dou X, Zhai S, Liu X
Journal of materials chemistry. B 2021 Mar 21;9(11):2641-2655
Journal of materials chemistry. B 2021 Mar 21;9(11):2641-2655
Identification of HOXA10 target genes in human endometrial stromal cells by RNA-seq analysis.
Wang Y, Hu S, Yao G, Sun Y
Acta biochimica et biophysica Sinica 2021 Mar 2;53(3):365-371
Acta biochimica et biophysica Sinica 2021 Mar 2;53(3):365-371
Clostridium Butyricum ZJU-F1 Benefits the Intestinal Barrier Function and Immune Response Associated with Its Modulation of Gut Microbiota in Weaned Piglets.
Fu J, Wang T, Xiao X, Cheng Y, Wang F, Jin M, Wang Y, Zong X
Cells 2021 Mar 2;10(3)
Cells 2021 Mar 2;10(3)
TagBiFC technique allows long-term single-molecule tracking of protein-protein interactions in living cells.
Shao S, Zhang H, Zeng Y, Li Y, Sun C, Sun Y
Communications biology 2021 Mar 19;4(1):378
Communications biology 2021 Mar 19;4(1):378
HDAC11 inhibition disrupts porcine oocyte meiosis via regulating α-tubulin acetylation and histone modifications.
Huang R, Sui L, Fu C, Zhai Y, Dai X, Zhang S, Li Z
Aging 2021 Mar 19;13(6):8849-8864
Aging 2021 Mar 19;13(6):8849-8864
CircSPI1 acts as an oncogene in acute myeloid leukemia through antagonizing SPI1 and interacting with microRNAs.
Wang X, Jin P, Zhang Y, Wang K
Cell death & disease 2021 Mar 19;12(4):297
Cell death & disease 2021 Mar 19;12(4):297
The MEK1/2 Pathway as a Therapeutic Target in High-Grade Serous Ovarian Carcinoma.
Chesnokov MS, Khan I, Park Y, Ezell J, Mehta G, Yousif A, Hong LJ, Buckanovich RJ, Takahashi A, Chefetz I
Cancers 2021 Mar 18;13(6)
Cancers 2021 Mar 18;13(6)
E3 Ubiquitin Ligase ASB17 Promotes Apoptosis by Ubiquitylating and Degrading BCLW and MCL1.
Yang G, Wan P, Xiang Q, Huang S, Huang S, Wang J, Wu K, Wu J
Biology 2021 Mar 18;10(3)
Biology 2021 Mar 18;10(3)
Kaempferol Reverses Aerobic Glycolysis via miR-339-5p-Mediated PKM Alternative Splicing in Colon Cancer Cells.
Wu H, Cui M, Li C, Li H, Dai Y, Cui K, Li Z
Journal of agricultural and food chemistry 2021 Mar 17;69(10):3060-3068
Journal of agricultural and food chemistry 2021 Mar 17;69(10):3060-3068
TMEM119 facilitates ovarian cancer cell proliferation, invasion, and migration via the PDGFRB/PI3K/AKT signaling pathway.
Sun T, Bi F, Liu Z, Yang Q
Journal of translational medicine 2021 Mar 17;19(1):111
Journal of translational medicine 2021 Mar 17;19(1):111
Rab26 suppresses migration and invasion of breast cancer cells through mediating autophagic degradation of phosphorylated Src.
Liu H, Zhou Y, Qiu H, Zhuang R, Han Y, Liu X, Qiu X, Wang Z, Xu L, Tan R, Hong W, Wang T
Cell death & disease 2021 Mar 17;12(4):284
Cell death & disease 2021 Mar 17;12(4):284
Astrocytic ApoE reprograms neuronal cholesterol metabolism and histone-acetylation-mediated memory.
Li X, Zhang J, Li D, He C, He K, Xue T, Wan L, Zhang C, Liu Q
Neuron 2021 Mar 17;109(6):957-970.e8
Neuron 2021 Mar 17;109(6):957-970.e8
TBC1D16 predicts chemosensitivity and prognosis in adult acute myeloid leukemia (AML) patients.
Liu H, Chen P, Yang YL, Zhu KW, Wang T, Tang L, Liu YL, Cao S, Zhou G, Zeng H, Zhao XL, Zhang W, Chen XP
European journal of pharmacology 2021 Mar 15;895:173894
European journal of pharmacology 2021 Mar 15;895:173894
GR/NF-κB signaling pathway regulates hippocampal inflammatory responses in diabetic rats with chronic unpredictable mild stress.
Li ZR, Han YS, Liu Z, Zhao HQ, Liu J, Yang H, Wang YH
European journal of pharmacology 2021 Mar 15;895:173861
European journal of pharmacology 2021 Mar 15;895:173861
PDX models reflect the proteome landscape of pediatric acute lymphoblastic leukemia but divert in select pathways.
Uzozie AC, Ergin EK, Rolf N, Tsui J, Lorentzian A, Weng SSH, Nierves L, Smith TG, Lim CJ, Maxwell CA, Reid GSD, Lange PF
Journal of experimental & clinical cancer research : CR 2021 Mar 15;40(1):96
Journal of experimental & clinical cancer research : CR 2021 Mar 15;40(1):96
Thrombin inhibitor argatroban modulates bone marrow stromal cells behaviors and promotes osteogenesis through canonical Wnt signaling.
Song J, Jiang N, Gan X, Zhi W, Zhu Z
Life sciences 2021 Mar 15;269:119073
Life sciences 2021 Mar 15;269:119073
Identification and functional analysis of senescence-associated secretory phenotype of premature senescent hepatocytes induced by hexavalent chromium.
Ma Y, Liang Y, Liang N, Zhang Y, Xiao F
Ecotoxicology and environmental safety 2021 Mar 15;211:111908
Ecotoxicology and environmental safety 2021 Mar 15;211:111908
The role of Se content in improving anti-tumor activities and its potential mechanism for selenized Artemisia sphaerocephala polysaccharides.
Liu S, Hu J, Li M, Zhu S, Guo S, Guo H, Wang T, Zhang Y, Zhang J, Wang J
Food & function 2021 Mar 15;12(5):2058-2074
Food & function 2021 Mar 15;12(5):2058-2074
MiR-1290 promotes myoblast differentiation and protects against myotube atrophy via Akt/p70/FoxO3 pathway regulation.
Che J, Xu C, Wu Y, Jia P, Han Q, Ma Y, Wang X, Zheng Y
Skeletal muscle 2021 Mar 15;11(1):6
Skeletal muscle 2021 Mar 15;11(1):6
Perilipin 5 ameliorates high-glucose-induced podocyte injury via Akt/GSK-3β/Nrf2-mediated suppression of apoptosis, oxidative stress, and inflammation.
Feng J, Xie L, Yu X, Liu C, Dong H, Lu W, Kong R
Biochemical and biophysical research communications 2021 Mar 12;544:22-30
Biochemical and biophysical research communications 2021 Mar 12;544:22-30
Citrus Alkaline Extracts Inhibit Senescence of A549 Cells to Alleviate Pulmonary Fibrosis via the β-Catenin/P53 Pathway.
Han D, Xu Y, Peng WP, Feng F, Wang Z, Gu C, Zhou X
Medical science monitor : international medical journal of experimental and clinical research 2021 Mar 12;27:e928547
Medical science monitor : international medical journal of experimental and clinical research 2021 Mar 12;27:e928547
Lnc13728 facilitates human mesenchymal stem cell adipogenic differentiation via positive regulation of ZBED3 and downregulation of the WNT/β-catenin pathway.
Xu H, Yang Y, Fan L, Deng L, Fan J, Li D, Li H, Zhao RC
Stem cell research & therapy 2021 Mar 12;12(1):176
Stem cell research & therapy 2021 Mar 12;12(1):176
Novel IMB16-4 Compound Loaded into Silica Nanoparticles Exhibits Enhanced Oral Bioavailability and Increased Anti-Liver Fibrosis In Vitro.
Niu X, Wang X, Niu B, Li G, Yang X, Wang Y, Li G
Molecules (Basel, Switzerland) 2021 Mar 11;26(6)
Molecules (Basel, Switzerland) 2021 Mar 11;26(6)
SRP54 mutations induce congenital neutropenia via dominant-negative effects on XBP1 splicing.
Schürch C, Schaefer T, Müller JS, Hanns P, Arnone M, Dumlin A, Schärer J, Sinning I, Wild K, Skokowa J, Welte K, Carapito R, Bahram S, Konantz M, Lengerke C
Blood 2021 Mar 11;137(10):1340-1352
Blood 2021 Mar 11;137(10):1340-1352
Isoliquiritigenin Reverses Epithelial-Mesenchymal Transition Through Modulation of the TGF-β/Smad Signaling Pathway in Endometrial Cancer.
Chen HY, Chiang YF, Huang JS, Huang TC, Shih YH, Wang KL, Ali M, Hong YH, Shieh TM, Hsia SM
Cancers 2021 Mar 11;13(6)
Cancers 2021 Mar 11;13(6)
MAGI1 inhibits the AMOTL2/p38 stress pathway and prevents luminal breast tumorigenesis.
Kantar D, Mur EB, Mancini M, Slaninova V, Salah YB, Costa L, Forest E, Lassus P, Géminard C, Boissière-Michot F, Orsetti B, Theillet C, Colinge J, Benistant C, Maraver A, Heron-Milhavet L, Djiane A
Scientific reports 2021 Mar 11;11(1):5752
Scientific reports 2021 Mar 11;11(1):5752
The role of irreversible electroporation in promoting M1 macrophage polarization via regulating the HMGB1-RAGE-MAPK axis in pancreatic cancer.
He C, Sun S, Zhang Y, Xie F, Li S
Oncoimmunology 2021 Mar 11;10(1):1897295
Oncoimmunology 2021 Mar 11;10(1):1897295
The LncRNA RP11-301G19.1/miR-582-5p/HMGB2 axis modulates the proliferation and apoptosis of multiple myeloma cancer cells via the PI3K/AKT signalling pathway.
Wang F, Luo Y, Zhang L, Younis M, Yuan L
Cancer gene therapy 2021 Mar 11;
Cancer gene therapy 2021 Mar 11;
Positive regulation of Type III secretion effectors and virulence by RyhB paralogs in Salmonella enterica serovar Enteritidis.
Chen B, Meng X, Ni J, He M, Chen Y, Xia P, Wang H, Liu S, Zhu G, Meng X
Veterinary research 2021 Mar 10;52(1):44
Veterinary research 2021 Mar 10;52(1):44
Downregulation of lncRNA ZNF582-AS1 due to DNA hypermethylation promotes clear cell renal cell carcinoma growth and metastasis by regulating the N(6)-methyladenosine modification of MT-RNR1.
Yang W, Zhang K, Li L, Xu Y, Ma K, Xie H, Zhou J, Cai L, Gong Y, Gong K
Journal of experimental & clinical cancer research : CR 2021 Mar 10;40(1):92
Journal of experimental & clinical cancer research : CR 2021 Mar 10;40(1):92
Endogenous conversion of n-6 to n-3 polyunsaturated fatty acids facilitates the repair of cardiotoxin-induced skeletal muscle injury in fat-1 mice.
Wang ZG, Zhu ZQ, He ZY, Cheng P, Liang S, Chen AM, Yang Q
Aging 2021 Mar 10;13(6):8454-8466
Aging 2021 Mar 10;13(6):8454-8466
Long Noncoding RNA DUXAP8 Promotes Pancreatic Carcinoma Cell Migration and Invasion Via Pathway by miR-448/WTAP/Fak Signaling Axis.
Li JR, Liu L, Luo H, Chen ZG, Wang JH, Li NF
Pancreas 2021 Mar 1;50(3):317-326
Pancreas 2021 Mar 1;50(3):317-326
TMEM2 binds to CSNK2A3 to inhibit HBV infection via activation of the JAK/STAT pathway.
Zhou H, Jia X, Hu K, Mo Z, Xu W, Peng L, Wang K, Zhu X
Experimental cell research 2021 Mar 1;400(1):112517
Experimental cell research 2021 Mar 1;400(1):112517
Cancer-associated fibroblasts promote the survival of irradiated nasopharyngeal carcinoma cells via the NF-κB pathway.
Huang W, Zhang L, Yang M, Wu X, Wang X, Huang W, Yuan L, Pan H, Wang Y, Wang Z, Wu Y, Huang J, Liang H, Li S, Liao L, Liu L, Guan J
Journal of experimental & clinical cancer research : CR 2021 Mar 1;40(1):87
Journal of experimental & clinical cancer research : CR 2021 Mar 1;40(1):87
Prematurity blunts the insulin- and amino acid-induced stimulation of translation initiation and protein synthesis in skeletal muscle of neonatal pigs.
Rudar M, Naberhuis JK, Suryawan A, Nguyen HV, Stoll B, Style CC, Verla MA, Olutoye OO, Burrin DG, Fiorotto ML, Davis TA
American journal of physiology. Endocrinology and metabolism 2021 Mar 1;320(3):E551-E565
American journal of physiology. Endocrinology and metabolism 2021 Mar 1;320(3):E551-E565
Endoplasmic Reticulum Stress-Mediated p62 Downregulation Inhibits Apoptosis via c-Jun Upregulation.
Yu W, Wang B, Zhou L, Xu G
Biomolecules & therapeutics 2021 Mar 1;29(2):195-204
Biomolecules & therapeutics 2021 Mar 1;29(2):195-204
Contributions of HO-1-Dependent MAPK to Regulating Intestinal Barrier Disruption.
Zhang Z, Zhang Q, Li F, Xin Y, Duan Z
Biomolecules & therapeutics 2021 Mar 1;29(2):175-183
Biomolecules & therapeutics 2021 Mar 1;29(2):175-183
Cadmium and molybdenum co-induce pyroptosis via ROS/PTEN/PI3K/AKT axis in duck renal tubular epithelial cells.
Zhang C, Lin T, Nie G, Hu R, Pi S, Wei Z, Wang C, Xing C, Hu G
Environmental pollution (Barking, Essex : 1987) 2021 Mar 1;272:116403
Environmental pollution (Barking, Essex : 1987) 2021 Mar 1;272:116403
Tubeimoside I promotes angiogenesis via activation of eNOS-VEGF signaling pathway.
Yang X, Li X, Luo M, Guo Y, Li C, Lv D, Cheng Z, Huang L, Shang FF, Huang B, Shen J, Luo S, Yan J
Journal of ethnopharmacology 2021 Mar 1;267:113642
Journal of ethnopharmacology 2021 Mar 1;267:113642
Benzo[a]pyrene induces fibrotic changes and impairs differentiation in lung stem cells.
Tseng YH, Chen YC, Yu AL, Yu J
Ecotoxicology and environmental safety 2021 Mar 1;210:111892
Ecotoxicology and environmental safety 2021 Mar 1;210:111892
Circulating Exosomes From Patients With Graves' Disease Induce an Inflammatory Immune Response.
Cui X, Huang M, Wang S, Zhao N, Huang T, Wang Z, Qiao J, Wang S, Shan Z, Teng W, Li Y
Endocrinology 2021 Mar 1;162(3)
Endocrinology 2021 Mar 1;162(3)
METTL3-mediated m6A modification regulates cell cycle progression of dental pulp stem cells.
Luo H, Liu W, Zhang Y, Yang Y, Jiang X, Wu S, Shao L
Stem cell research & therapy 2021 Mar 1;12(1):159
Stem cell research & therapy 2021 Mar 1;12(1):159
Iguratimod-encapsulating PLGA-NPs induce human multiple myeloma cell death via reactive oxygen species and Caspase-dependent signalling.
Wang F, Younis M, Luo Y, Zhang L, Yuan L
International immunopharmacology 2021 Jun;95:107532
International immunopharmacology 2021 Jun;95:107532
Tumor protein D52 promotes breast cancer proliferation and migration via the long non-coding RNA NEAT1/microRNA-218-5p axis.
Ren J, Chen Y, Kong W, Li Y, Lu F
Annals of translational medicine 2021 Jun;9(12):1008
Annals of translational medicine 2021 Jun;9(12):1008
Overexpression of lipoic acid synthase gene alleviates diabetic nephropathy of Leprdb/db mice.
Zhao Y, Yan T, Xiong C, Chang M, Gao Q, Yao S, Wu W, Yi X, Xu G
BMJ open diabetes research & care 2021 Jun;9(1)
BMJ open diabetes research & care 2021 Jun;9(1)
Vitexin exerts protective effects against calcium oxalate crystal-induced kidney pyroptosis in vivo and in vitro.
Ding T, Zhao T, Li Y, Liu Z, Ding J, Ji B, Wang Y, Guo Z
Phytomedicine : international journal of phytotherapy and phytopharmacology 2021 Jun;86:153562
Phytomedicine : international journal of phytotherapy and phytopharmacology 2021 Jun;86:153562
PFKP facilitates ATG4B phosphorylation during amino acid deprivation-induced autophagy.
Li X, Sun L, Yan G, Yan X
Cellular signalling 2021 Jun;82:109956
Cellular signalling 2021 Jun;82:109956
Suberoylanilide Hydroxamic Acid (SAHA) Reduces Fibrosis Markers and Deactivates Human Stellate Cells via the Epithelial-Mesenchymal Transition (EMT).
Özel M, Baskol M, Akalın H, Baskol G
Cell biochemistry and biophysics 2021 Jun;79(2):349-357
Cell biochemistry and biophysics 2021 Jun;79(2):349-357
Human SND2 mediates ER targeting of GPI-anchored proteins with low hydrophobic GPI attachment signals.
Yang J, Hirata T, Liu YS, Guo XY, Gao XD, Kinoshita T, Fujita M
FEBS letters 2021 Jun;595(11):1542-1558
FEBS letters 2021 Jun;595(11):1542-1558
A phase-separated nuclear GBPL circuit controls immunity in plants.
Huang S, Zhu S, Kumar P, MacMicking JD
Nature 2021 Jun;594(7863):424-429
Nature 2021 Jun;594(7863):424-429
Carbon monoxide alleviates senescence in diabetic nephropathy by improving autophagy.
Chen L, Mei G, Jiang C, Cheng X, Li D, Zhao Y, Chen H, Wan C, Yao P, Gao C, Tang Y
Cell proliferation 2021 Jun;54(6):e13052
Cell proliferation 2021 Jun;54(6):e13052
Attenuation of the upregulation of NF‑κB and AP‑1 DNA‑binding activities induced by tunicamycin or hypoxia/reoxygenation in neonatal rat cardiomyocytes by SERCA2a overexpression.
Qu Z, Lu X, Qu Y, Tao T, Liu X, Li X
International journal of molecular medicine 2021 Jun;47(6)
International journal of molecular medicine 2021 Jun;47(6)
Long non‑coding RNA MIR4435‑2HG promotes the progression of head and neck squamous cell carcinoma by regulating the miR‑383‑5p/RBM3 axis.
Wang S, Chen X, Qiao T
Oncology reports 2021 Jun;45(6)
Oncology reports 2021 Jun;45(6)
Differentially expressed proteins identified by TMT proteomics analysis in children with verrucous epidermal naevi.
Yuan T, Cai ML, Sheng YM, Ding X, Shen TT, Li WR, Huang H, Liang B, Zhang XJ, Zhu QX
Journal of the European Academy of Dermatology and Venereology : JEADV 2021 Jun;35(6):1393-1406
Journal of the European Academy of Dermatology and Venereology : JEADV 2021 Jun;35(6):1393-1406
Mutual dependency between lncRNA LETN and protein NPM1 in controlling the nucleolar structure and functions sustaining cell proliferation.
Wang X, Hu X, Song W, Xu H, Xiao Z, Huang R, Bai Q, Zhang F, Chen Y, Liu Y, Fang J, Li X, Shen Q, Zhao H, Yang X
Cell research 2021 Jun;31(6):664-683
Cell research 2021 Jun;31(6):664-683
Generation and identification of endothelial-specific Hrh2 knockout mice.
Meng R, Cai WK, Xu WM, Feng Q, Wang P, Huang YH, Fan YX, Zhou T, Yang Q, Li ZR, He GH
Transgenic research 2021 Jun;30(3):251-261
Transgenic research 2021 Jun;30(3):251-261
Comprehensive interactome analysis of the spike protein of swine acute diarrhea syndrome coronavirus.
Wang Q, Luo Y, Shang W, Shi Z, Xiao G, Zhang L
Biosafety and health 2021 Jun;3(3):156-163
Biosafety and health 2021 Jun;3(3):156-163
Targeting IDH1/2 mutant cancers with combinations of ATR and PARP inhibitors.
Sule A, Van Doorn J, Sundaram RK, Ganesa S, Vasquez JC, Bindra RS
NAR cancer 2021 Jun;3(2):zcab018
NAR cancer 2021 Jun;3(2):zcab018
Matrix stiffness-mediated effects on macrophages polarization and their LOXL2 expression.
Xing X, Wang Y, Zhang X, Gao X, Li M, Wu S, Zhao Y, Chen J, Gao D, Chen R, Ren Z, Zhang K, Cui J
The FEBS journal 2021 Jun;288(11):3465-3477
The FEBS journal 2021 Jun;288(11):3465-3477
Lipotoxicity suppresses the synthesis of growth hormone in pituitary somatotrophs via endoplasmic reticulum stress.
Gong Y, Yang J, Wei S, Yang R, Gao L, Shao S, Zhao J
Journal of cellular and molecular medicine 2021 Jun;25(11):5250-5259
Journal of cellular and molecular medicine 2021 Jun;25(11):5250-5259
Rescue of maternal immune activation-induced behavioral abnormalities in adult mouse offspring by pathogen-activated maternal Treg cells.
Xu Z, Zhang X, Chang H, Kong Y, Ni Y, Liu R, Zhang X, Hu Y, Yang Z, Hou M, Mao R, Liu WT, Du Y, Yu S, Wang Z, Ji M, Zhou Z
Nature neuroscience 2021 Jun;24(6):818-830
Nature neuroscience 2021 Jun;24(6):818-830
Crosstalk between the COX2-PGE2-EP4 signaling pathway and primary cilia in osteoblasts after mechanical stimulation.
Li YH, Zhu D, Yang T, Cheng L, Sun J, Tan L
Journal of cellular physiology 2021 Jun;236(6):4764-4777
Journal of cellular physiology 2021 Jun;236(6):4764-4777
Acvr1 deletion in osteoblasts impaired mandibular bone mass through compromised osteoblast differentiation and enhanced sRANKL-induced osteoclastogenesis.
Hu Y, Hao X, Liu C, Ren C, Wang S, Yan G, Meng Y, Mishina Y, Shi C, Sun H
Journal of cellular physiology 2021 Jun;236(6):4580-4591
Journal of cellular physiology 2021 Jun;236(6):4580-4591
SOD3 deficiency induces liver fibrosis by promoting hepatic stellate cell activation and epithelial-mesenchymal transition.
Sun YL, Bai T, Zhou L, Zhu RT, Wang WJ, Liang RP, Li J, Zhang CX, Gou JJ
Journal of cellular physiology 2021 Jun;236(6):4313-4329
Journal of cellular physiology 2021 Jun;236(6):4313-4329
Dioscin inhibits SCC15 cell proliferation via the RASSF1A/MST2/YAP axis.
Tian H, Chen X, Zhang Y, Wang Y, Fu X, Gu W, Wen Y
Molecular medicine reports 2021 Jun;23(6)
Molecular medicine reports 2021 Jun;23(6)
SEC61G is upregulated and required for tumor progression in human kidney cancer.
Meng H, Jiang X, Wang J, Sang Z, Guo L, Yin G, Wang Y
Molecular medicine reports 2021 Jun;23(6)
Molecular medicine reports 2021 Jun;23(6)
Salidroside overcomes dexamethasone resistance in T-acute lymphoblastic leukemia cells.
Niu YN, Zeng Y, Zhong FF, Long SL, Ren DW, Qin X, Liu WJ
Experimental and therapeutic medicine 2021 Jun;21(6):636
Experimental and therapeutic medicine 2021 Jun;21(6):636
Ginkgo biloba delays light-induced photoreceptor degeneration through antioxidant and antiapoptotic properties.
Chudhary M, Zhang C, Song S, Ren X, Kong L
Experimental and therapeutic medicine 2021 Jun;21(6):576
Experimental and therapeutic medicine 2021 Jun;21(6):576
Oncogenic WIP1 phosphatase attenuates the DNA damage response and sensitizes p53 mutant Jurkat cells to apoptosis.
Eren MK, Kartal NB, Pilevneli H
Oncology letters 2021 Jun;21(6):479
Oncology letters 2021 Jun;21(6):479
PHD Finger Protein 19 Promotes Cardiac Hypertrophy via Epigenetically Regulating SIRT2.
Gu W, Cheng Y, Wang S, Sun T, Li Z
Cardiovascular toxicology 2021 Jun;21(6):451-461
Cardiovascular toxicology 2021 Jun;21(6):451-461
DEK is highly expressed in breast cancer and is associated with malignant phenotype and progression.
Yang MQ, Bai LL, Wang Z, Lei L, Zheng YW, Li ZH, Huang WJ, Liu CC, Xu HT
Oncology letters 2021 Jun;21(6):440
Oncology letters 2021 Jun;21(6):440
Long noncoding RNA PM maintains cerebellar synaptic integrity and Cbln1 activation via Pax6/Mll1-mediated H3K4me3.
Jin Y, Zhang B, Lu J, Song Y, Wang W, Zhang W, Shao F, Gong M, Wang M, Liang X, Li S, Zhang Z, Shan G, Wang X
PLoS biology 2021 Jun;19(6):e3001297
PLoS biology 2021 Jun;19(6):e3001297
Ketoplatin in triple-negative breast cancer cells MDA-MB-231: High efficacy and low toxicity, and positive impact on inflammatory microenvironment.
Ma ZY, Song XQ, Hu JJ, Wang DB, Ding XJ, Liu RP, Dai ML, Meng FY, Xu JY
Biochemical pharmacology 2021 Jun;188:114523
Biochemical pharmacology 2021 Jun;188:114523
Virus-inducible IGFALS facilitates innate immune responses by mediating IRAK1 and TRAF6 activation.
Xu G, Deng F, Zuo Q, Liu L, Dou K, Cheng Z, Cao W, Luo C, Yu C, Liu S, Zhu Y
Cellular & molecular immunology 2021 Jun;18(6):1587-1589
Cellular & molecular immunology 2021 Jun;18(6):1587-1589
T-17, a spirostanol saponin, inhibits p53-independent proliferation and p53-dependent migration of gastric cancer cells.
Xu J, Wang Y, Wang Z, Wang Y, He X
Steroids 2021 Jun;170:108828
Steroids 2021 Jun;170:108828
SNX-3 mediates retromer-independent tubular endosomal recycling by opposing EEA-1-facilitated trafficking.
Tian Y, Kang Q, Shi X, Wang Y, Zhang N, Ye H, Xu Q, Xu T, Zhang R
PLoS genetics 2021 Jun;17(6):e1009607
PLoS genetics 2021 Jun;17(6):e1009607
NIR-II Absorbing Semiconducting Polymer-Triggered Gene-Directed Enzyme Prodrug Therapy for Cancer Treatment.
Zhang X, Yang Y, Kang T, Wang J, Yang G, Yang Y, Lin X, Wang L, Li K, Liu J, Ni JS
Small (Weinheim an der Bergstrasse, Germany) 2021 Jun;17(23):e2100501
Small (Weinheim an der Bergstrasse, Germany) 2021 Jun;17(23):e2100501
PPARα agonist WY-14,643 enhances ethanol metabolism in mice: Role of catalase.
Chen X, Xu Y, Denning KL, Grigore A, Lu Y
Free radical biology & medicine 2021 Jun;169:283-293
Free radical biology & medicine 2021 Jun;169:283-293
Paricalcitol inhibits oxidative stress-induced cell senescence of the bile duct epithelium dependent on modulating Sirt1 pathway in cholestatic mice.
Jia R, Yang F, Yan P, Ma L, Yang L, Li L
Free radical biology & medicine 2021 Jun;169:158-168
Free radical biology & medicine 2021 Jun;169:158-168
Unbiased proteomic screening identifies a novel role for the E3 ubiquitin ligase Nedd4-2 in translational suppression during ER stress.
Eagleman DE, Zhu J, Liu DC, Seimetz J, Kalsotra A, Tsai NP
Journal of neurochemistry 2021 Jun;157(6):1809-1820
Journal of neurochemistry 2021 Jun;157(6):1809-1820
ALS-causing SOD1 mutants regulate occludin phosphorylation/ubiquitination and endocytic trafficking via the ITCH/Eps15/Rab5 axis.
Tang J, Kang Y, Zhou Y, Li X, Lan J, Wu L, Feng X, Peng Y
Neurobiology of disease 2021 Jun;153:105315
Neurobiology of disease 2021 Jun;153:105315
Prohibitin regulates mTOR pathway via interaction with FKBP8.
Zhang J, Yin Y, Wang J, Zhang J, Liu H, Feng W, Yang W, Zetter B, Xu Y
Frontiers of medicine 2021 Jun;15(3):448-459
Frontiers of medicine 2021 Jun;15(3):448-459
AMD3465 (hexahydrobromide) rescues the MG63 osteoblasts against the apoptosis induced by high glucose.
Zhang Z, Wu H, Huang S, Chen L, Chen X, Zhang W, Liao L, Zhang X
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Jun;138:111476
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Jun;138:111476
Gu-Ben-Fang-Xiao decoction modulates lipid metabolism by activating the AMPK pathway in asthma remission.
You YN, Xing QQ, Zhao X, Ji JJ, Yan H, Zhou T, Dong YM, Ren LS, Hou ST, Ding YY
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Jun;138:111403
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Jun;138:111403
Nuclear m6A reader YTHDC1 regulates the scaffold function of LINE1 RNA in mouse ESCs and early embryos.
Chen C, Liu W, Guo J, Liu Y, Liu X, Liu J, Dou X, Le R, Huang Y, Li C, Yang L, Kou X, Zhao Y, Wu Y, Chen J, Wang H, Shen B, Gao Y, Gao S
Protein & cell 2021 Jun;12(6):455-474
Protein & cell 2021 Jun;12(6):455-474
Design, synthesis and biological evaluation of anilide (dicarboxylic acid) shikonin esters as antitumor agents through targeting PI3K/Akt/mTOR signaling pathway.
Ma Y, Yang X, Han H, Wen Z, Yang M, Zhang Y, Fu J, Wang X, Yin T, Lu G, Qi J, Lin H, Wang X, Yang Y
Bioorganic chemistry 2021 Jun;111:104872
Bioorganic chemistry 2021 Jun;111:104872
C/EBPδ drives key endocrine signals in the human amnion at parturition.
Lu JW, Wang WS, Zhou Q, Ling LJ, Ying H, Sun Y, Myatt L, Sun K
Clinical and translational medicine 2021 Jun;11(6):e416
Clinical and translational medicine 2021 Jun;11(6):e416
HYD-PEP06 suppresses hepatocellular carcinoma metastasis, epithelial-mesenchymal transition and cancer stem cell-like properties by inhibiting PI3K/AKT and WNT/β-catenin signaling activation.
Tian W, Li J, Wang Z, Zhang T, Han Y, Liu Y, Chu W, Liu Y, Yang B
Acta pharmaceutica Sinica. B 2021 Jun;11(6):1592-1606
Acta pharmaceutica Sinica. B 2021 Jun;11(6):1592-1606
Metformin Carbon Dots for Promoting Periodontal Bone Regeneration via Activation of ERK/AMPK Pathway.
Ren C, Hao X, Wang L, Hu Y, Meng L, Zheng S, Ren F, Bu W, Wang H, Li D, Zhang K, Sun H
Advanced healthcare materials 2021 Jun;10(12):e2100196
Advanced healthcare materials 2021 Jun;10(12):e2100196
PARP inhibitors promote stromal fibroblast activation by enhancing CCL5 autocrine signaling in ovarian cancer.
Li X, Fang T, Xu S, Jin P, Zhou D, Wang Z, Li H, Yang Z, Chen G, Zheng X, Xia Y, Wei X, Zhang Z, Yang X, Wang Y, Gao Q
NPJ precision oncology 2021 Jun 9;5(1):49
NPJ precision oncology 2021 Jun 9;5(1):49
CircC16orf62 promotes hepatocellular carcinoma progression through the miR-138-5p/PTK2/AKT axis.
Zhang S, Lu Y, Jiang HY, Cheng ZM, Wei ZJ, Wei YH, Liu T, Xia BJ, Zhao XY, Huang Y, Zou X, Liu R, Zhou S
Cell death & disease 2021 Jun 9;12(6):597
Cell death & disease 2021 Jun 9;12(6):597
SARS-CoV-2 exacerbates proinflammatory responses in myeloid cells through C-type lectin receptors and Tweety family member 2.
Lu Q, Liu J, Zhao S, Gomez Castro MF, Laurent-Rolle M, Dong J, Ran X, Damani-Yokota P, Tang H, Karakousi T, Son J, Kaczmarek ME, Zhang Z, Yeung ST, McCune BT, Chen RE, Tang F, Ren X, Chen X, Hsu JCC, Teplova M, Huang B, Deng H, Long Z, Mudianto T, Jin S, Lin P, Du J, Zang R, Su TT, Herrera A, Zhou M, Yan R, Cui J, Zhu J, Zhou Q, Wang T, Ma J, Koralov SB, Zhang Z, Aifantis I, Segal LN, Diamond MS, Khanna KM, Stapleford KA, Cresswell P, Liu Y, Ding S, Xie Q, Wang J
Immunity 2021 Jun 8;54(6):1304-1319.e9
Immunity 2021 Jun 8;54(6):1304-1319.e9
Attenuation by HSP90 inhibitors of EGF-elicited migration of osteoblasts: involvement of p44/p42 MAP kinase.
Kuroyanagi G, Kawabata T, Tokuda H, Fujita K, Matsushima-Nishiwaki R, Sakai G, Tachi J, Hioki T, Kim W, Iida H, Otsuka T, Kozawa O
Connective tissue research 2021 Jun 8;:1-11
Connective tissue research 2021 Jun 8;:1-11
SNP rs10420324 in the AMPA receptor auxiliary subunit TARP γ-8 regulates the susceptibility to antisocial personality disorder.
Peng SX, Wang YY, Zhang M, Zang YY, Wu D, Pei J, Li Y, Dai J, Guo X, Luo X, Zhang N, Yang JJ, Zhang C, Gao X, Liu N, Shi YS
Scientific reports 2021 Jun 7;11(1):11997
Scientific reports 2021 Jun 7;11(1):11997
Chronic exposure to PFO4DA and PFO5DoDA, two perfluoroalkyl ether carboxylic acids (PFECAs), suppresses hepatic stress signals and disturbs glucose and lipid metabolism in male mice.
Chen J, Li H, Yao J, Guo H, Zhang H, Guo Y, Sheng N, Wang J, Dai J
Journal of hazardous materials 2021 Jun 5;411:124963
Journal of hazardous materials 2021 Jun 5;411:124963
The functional characterization of phosphorylation of tristetraprolin at C-terminal NOT1-binding domain.
Hsieh HH, Chen YA, Chang YJ, Wang HH, Yu YH, Lin SW, Huang YJ, Lin S, Chang CJ
Journal of inflammation (London, England) 2021 Jun 5;18(1):22
Journal of inflammation (London, England) 2021 Jun 5;18(1):22
Gankyrin activates the hedgehog signalling to drive metastasis in osteosarcoma.
Wang C, Jing J, Hu X, Yu S, Yao F, Li Z, Cheng L
Journal of cellular and molecular medicine 2021 Jun 5;
Journal of cellular and molecular medicine 2021 Jun 5;
Design, synthesis, and neuroprotective effects of novel hybrid compounds containing edaravone analogue and 3-n-butylphthalide ring-opened derivatives.
Li X, Wang X, Miao L, Guo Y, Yuan R, Tian H
Biochemical and biophysical research communications 2021 Jun 4;556:99-105
Biochemical and biophysical research communications 2021 Jun 4;556:99-105
Protective effects of prucalopride in MPTP-induced Parkinson's disease mice: Neurochemistry, motor function and gut barrier.
Shi Y, Qiao CM, Zhou Y, Wu J, Cui C, Hong H, Jia XB, Huang SB, Yao L, Zhao WJ, Shen YQ
Biochemical and biophysical research communications 2021 Jun 4;556:16-22
Biochemical and biophysical research communications 2021 Jun 4;556:16-22
Matrine suppresses cell growth of diffuse large B-cell lymphoma via inhibiting CaMKIIγ/c-Myc/CDK6 signaling pathway.
Gu J, Wang X, Zhang L, Xiang J, Li J, Chen Z, Zhang Y, Chen J, Shen J
BMC complementary medicine and therapies 2021 Jun 4;21(1):163
BMC complementary medicine and therapies 2021 Jun 4;21(1):163
YTHDF1 promotes hepatocellular carcinoma progression via activating PI3K/AKT/mTOR signaling pathway and inducing epithelial-mesenchymal transition.
Luo X, Cao M, Gao F, He X
Experimental hematology & oncology 2021 Jun 4;10(1):35
Experimental hematology & oncology 2021 Jun 4;10(1):35
Formin-like protein 2 promotes cell proliferation by a p27-related mechanism in human breast cancer cells.
Jiao X, Wang B, Feng C, Song S, Tian B, Zhou C, Gao X, Sun W, Liu P
BMC cancer 2021 Jun 30;21(1):760
BMC cancer 2021 Jun 30;21(1):760
Self-stabilizing regulation of deubiquitinating enzymes in an enzymatic activity-dependent manner.
Hou Z, Shi W, Feng J, Wang W, Zheng E, Lin H, Yu C, Li L
International journal of biological macromolecules 2021 Jun 30;181:1081-1091
International journal of biological macromolecules 2021 Jun 30;181:1081-1091
The lipid-lowering drug fenofibrate combined with si-HOTAIR can effectively inhibit the proliferation of gliomas.
Zhu W, Zhao H, Xu F, Huang B, Dai X, Sun J, Nyalali AMK, Zhang K, Ni S
BMC cancer 2021 Jun 3;21(1):664
BMC cancer 2021 Jun 3;21(1):664
IL-37b alleviates endothelial cell apoptosis and inflammation in Kawasaki disease through IL-1R8 pathway.
Jia C, Zhuge Y, Zhang S, Ni C, Wang L, Wu R, Niu C, Wen Z, Rong X, Qiu H, Chu M
Cell death & disease 2021 Jun 3;12(6):575
Cell death & disease 2021 Jun 3;12(6):575
The CTNNBIP1-CLSTN1 fusion transcript regulates human neocortical development.
Ou MY, Xiao Q, Ju XC, Zeng PM, Huang J, Sheng AL, Luo ZG
Cell reports 2021 Jun 29;35(13):109290
Cell reports 2021 Jun 29;35(13):109290
HCP5, as the sponge of miR-1291, facilitates AML cell proliferation and restrains apoptosis via increasing PIK3R5 expression.
Liu Y, Jing XB, Wang ZC, Han QK
Human genomics 2021 Jun 29;15(1):38
Human genomics 2021 Jun 29;15(1):38
Trim21-mediated HIF-1α degradation attenuates aerobic glycolysis to inhibit renal cancer tumorigenesis and metastasis.
Chen X, Li Z, Yong H, Wang W, Wang D, Chu S, Li M, Hou P, Zheng J, Bai J
Cancer letters 2021 Jun 28;508:115-126
Cancer letters 2021 Jun 28;508:115-126
A network-based analysis and experimental validation of traditional Chinese medicine Yuanhu Zhitong Formula in treating neuropathic pain.
Liu T, Li T, Chen X, Zhang K, Li M, Yao W, Zhang C, Wan L
Journal of ethnopharmacology 2021 Jun 28;274:114037
Journal of ethnopharmacology 2021 Jun 28;274:114037
Ginsenoside Rh2 alleviates ulcerative colitis by regulating the STAT3/miR-214 signaling pathway.
Chen X, Xu T, Lv X, Zhang J, Liu S
Journal of ethnopharmacology 2021 Jun 28;274:113997
Journal of ethnopharmacology 2021 Jun 28;274:113997
Smek1 deficiency exacerbates experimental autoimmune encephalomyelitis by activating proinflammatory microglia and suppressing the IDO1-AhR pathway.
Duan RN, Yang CL, Du T, Liu A, Wang AR, Sun WJ, Li X, Li JX, Yan CZ, Liu QJ
Journal of neuroinflammation 2021 Jun 28;18(1):145
Journal of neuroinflammation 2021 Jun 28;18(1):145
The Anti-Tumor Effect and Underlying Apoptotic Mechanism of Ginsenoside Rk1 and Rg5 in Human Liver Cancer Cells.
Chen C, Lv Q, Li Y, Jin YH
Molecules (Basel, Switzerland) 2021 Jun 27;26(13)
Molecules (Basel, Switzerland) 2021 Jun 27;26(13)
Follicle-stimulating hormone worsens osteoarthritis by causing inflammation and chondrocyte dedifferentiation.
Huan Z, Wang Y, Zhang M, Zhang X, Liu Y, Kong L, Xu J
FEBS open bio 2021 Jun 27;
FEBS open bio 2021 Jun 27;
An integrative transcriptome study reveals Ddit4/Redd1 as a key regulator of cancer cachexia in rodent models.
Niu M, Li L, Su Z, Wei L, Pu W, Zhao C, Ding Y, Wazir J, Cao W, Song S, Gao Q, Wang H
Cell death & disease 2021 Jun 26;12(7):652
Cell death & disease 2021 Jun 26;12(7):652
NOL4L, a novel nuclear protein, promotes cell proliferation and metastasis by enhancing the PI3K/AKT pathway in ovarian cancer.
Lin F, Zhou J, Li X, Wang X
Biochemical and biophysical research communications 2021 Jun 25;559:121-128
Biochemical and biophysical research communications 2021 Jun 25;559:121-128
Circ3823 contributes to growth, metastasis and angiogenesis of colorectal cancer: involvement of miR-30c-5p/TCF7 axis.
Guo Y, Guo Y, Chen C, Fan D, Wu X, Zhao L, Shao B, Sun Z, Ji Z
Molecular cancer 2021 Jun 25;20(1):93
Molecular cancer 2021 Jun 25;20(1):93
SNAT2/SLC38A2 Confers the Stemness of Gastric Cancer Cells via Regulating Glutamine Level.
Nie K, Cai M
Digestive diseases and sciences 2021 Jun 25;
Digestive diseases and sciences 2021 Jun 25;
A knockout cell library of GPI biosynthetic genes for functional studies of GPI-anchored proteins.
Liu SS, Liu YS, Guo XY, Murakami Y, Yang G, Gao XD, Kinoshita T, Fujita M
Communications biology 2021 Jun 23;4(1):777
Communications biology 2021 Jun 23;4(1):777
Ferryl Hemoglobin and Heme Induce A1-Microglobulin in Hemorrhaged Atherosclerotic Lesions with Inhibitory Function against Hemoglobin and Lipid Oxidation.
Pethő D, Gáll T, Hendrik Z, Nagy A, Beke L, Gergely AP, Méhes G, Tóth C, Gram M, Åkerström B, Balla G, Balla J
International journal of molecular sciences 2021 Jun 22;22(13)
International journal of molecular sciences 2021 Jun 22;22(13)
Tissue- and stage-specific landscape of the mouse translatome.
Wang H, Wang Y, Yang J, Zhao Q, Tang N, Chen C, Li H, Cheng C, Xie M, Yang Y, Xie Z
Nucleic acids research 2021 Jun 21;49(11):6165-6180
Nucleic acids research 2021 Jun 21;49(11):6165-6180
m6A RNA hypermethylation-induced BACE2 boosts intracellular calcium release and accelerates tumorigenesis of ocular melanoma.
He F, Yu J, Yang J, Wang S, Zhuang A, Shi H, Gu X, Xu X, Chai P, Jia R
Molecular therapy : the journal of the American Society of Gene Therapy 2021 Jun 2;29(6):2121-2133
Molecular therapy : the journal of the American Society of Gene Therapy 2021 Jun 2;29(6):2121-2133
Effects of WNT1 c.110 T>C and c.505G>T mutations on osteoblast differentiation via the WNT1/β-catenin signaling pathway.
Zhang B, Li R, Wang W, Zhou X, Luo B, Zhu Z, Zhang X, Ding A
Journal of orthopaedic surgery and research 2021 Jun 2;16(1):359
Journal of orthopaedic surgery and research 2021 Jun 2;16(1):359
Mesenchymal stem cells ameliorate silica-induced pulmonary fibrosis by inhibition of inflammation and epithelial-mesenchymal transition.
Wei J, Zhao Q, Yang G, Huang R, Li C, Qi Y, Hao C, Yao W
Journal of cellular and molecular medicine 2021 Jun 2;
Journal of cellular and molecular medicine 2021 Jun 2;
TROAP regulates cell cycle and promotes tumor progression through Wnt/β-Catenin signaling pathway in glioma cells.
Zhao ZQ, Wu XJ, Cheng YH, Zhou YF, Ma XM, Zhang J, Heng XY, Feng F
CNS neuroscience & therapeutics 2021 Jun 2;
CNS neuroscience & therapeutics 2021 Jun 2;
A protocol for in vivo analysis of liver tumorigenesis in mice using sleeping beauty transposon system.
He L, Yu W, Lu Y, Zhang W, Xu J, Zhang L
STAR protocols 2021 Jun 18;2(2):100445
STAR protocols 2021 Jun 18;2(2):100445
Hypoxic postconditioning promotes mitophagy against transient global cerebral ischemia via PINK1/Parkin-induced mitochondrial ubiquitination in adult rats.
Wen H, Li L, Zhan L, Zuo Y, Li K, Qiu M, Li H, Sun W, Xu E
Cell death & disease 2021 Jun 18;12(7):630
Cell death & disease 2021 Jun 18;12(7):630
Long noncoding RNA AFAP1-AS1 promotes tumor progression and invasion by regulating the miR-2110/Sp1 axis in triple-negative breast cancer.
Zhang X, Li F, Zhou Y, Mao F, Lin Y, Shen S, Li Y, Zhang S, Sun Q
Cell death & disease 2021 Jun 18;12(7):627
Cell death & disease 2021 Jun 18;12(7):627
Arginine methylation of METTL14 promotes RNA N6-methyladenosine modification and endoderm differentiation of mouse embryonic stem cells.
Liu X, Wang H, Zhao X, Luo Q, Wang Q, Tan K, Wang Z, Jiang J, Cui J, Du E, Xia L, Du W, Chen D, Xia L, Xiao S
Nature communications 2021 Jun 18;12(1):3780
Nature communications 2021 Jun 18;12(1):3780
ALS/FTD mutations in UBQLN2 are linked to mitochondrial dysfunction through loss-of-function in mitochondrial protein import.
Lin BC, Phung TH, Higgins NR, Greenslade JE, Prado MA, Finley D, Karbowski M, Polster BM, Monteiro MJ
Human molecular genetics 2021 Jun 17;30(13):1230-1246
Human molecular genetics 2021 Jun 17;30(13):1230-1246
Single-cell RNA-seq reveals fibroblast heterogeneity and increased mesenchymal fibroblasts in human fibrotic skin diseases.
Deng CC, Hu YF, Zhu DH, Cheng Q, Gu JJ, Feng QL, Zhang LX, Xu YP, Wang D, Rong Z, Yang B
Nature communications 2021 Jun 17;12(1):3709
Nature communications 2021 Jun 17;12(1):3709
OGA is associated with deglycosylation of NONO and the KU complex during DNA damage repair.
Cui Y, Xie R, Zhang X, Liu Y, Hu Y, Li Y, Liu X, Yu X, Wu C
Cell death & disease 2021 Jun 16;12(7):622
Cell death & disease 2021 Jun 16;12(7):622
Exosomal SNHG16 secreted by CSCs promotes glioma development via TLR7.
Zhang R, Li P, Lv H, Li N, Ren S, Xu W
Stem cell research & therapy 2021 Jun 16;12(1):349
Stem cell research & therapy 2021 Jun 16;12(1):349
UBQLN2-HSP70 axis reduces poly-Gly-Ala aggregates and alleviates behavioral defects in the C9ORF72 animal model.
Zhang K, Wang A, Zhong K, Qi S, Wei C, Shu X, Tu WY, Xu W, Xia C, Xiao Y, Chen A, Bai L, Zhang J, Luo B, Wang W, Shen C
Neuron 2021 Jun 16;109(12):1949-1962.e6
Neuron 2021 Jun 16;109(12):1949-1962.e6
Cold Atmospheric Plasma Promotes Killing of Staphylococcus aureus by Macrophages.
Duchesne C, Frescaline N, Blaise O, Lataillade JJ, Banzet S, Dussurget O, Rousseau A
mSphere 2021 Jun 16;:e0021721
mSphere 2021 Jun 16;:e0021721
MicroRNA-139 inhibits pancreatic-cancer carcinogenesis by suppressing RalB via the Ral/RAC/PI3K pathway.
Wang Y, Zheng Y, Chen Q, Dai Y, Li T
Archives of biochemistry and biophysics 2021 Jun 15;704:108719
Archives of biochemistry and biophysics 2021 Jun 15;704:108719
Nimodipine inhibits intestinal and aortic smooth muscle contraction by regulating Ca2+-activated Cl- channels.
Wang H, Ma D, Zhu X, Liu P, Li S, Yu B, Yang H
Toxicology and applied pharmacology 2021 Jun 15;421:115543
Toxicology and applied pharmacology 2021 Jun 15;421:115543
Mechanosensitive expression of lamellipodin promotes intracellular stiffness, cyclin expression and cell proliferation.
Brazzo JA, Biber JC, Nimmer E, Heo Y, Ying L, Zhao R, Lee K, Krause M, Bae Y
Journal of cell science 2021 Jun 15;134(12)
Journal of cell science 2021 Jun 15;134(12)
Prrx1 promotes stemness and angiogenesis via activating TGF-β/smad pathway and upregulating proangiogenic factors in glioma.
Chen Z, Chen Y, Li Y, Lian W, Zheng K, Zhang Y, Zhang Y, Lin C, Liu C, Sun F, Sun X, Wang J, Zhao L, Ke Y
Cell death & disease 2021 Jun 15;12(6):615
Cell death & disease 2021 Jun 15;12(6):615
G-protein-coupled receptor GPR17 inhibits glioma development by increasing polycomb repressive complex 1-mediated ROS production.
Liu H, Xing R, Ou Z, Zhao J, Hong G, Zhao TJ, Han Y, Chen Y
Cell death & disease 2021 Jun 12;12(6):610
Cell death & disease 2021 Jun 12;12(6):610
RNF220-mediated ubiquitination promotes aggresomal accumulation and autophagic degradation of cytoplasmic Gli via HDAC6.
Wang H, Yang C, Li Y, Zhao S, Ma P, Mao B
Biochemical and biophysical research communications 2021 Jun 11;557:323-328
Biochemical and biophysical research communications 2021 Jun 11;557:323-328
Vincristine attenuates cardiac fibrosis through the inhibition of NLRP3 inflammasome activation.
Ge C, Cheng Y, Fan Y, He Y
Clinical science (London, England : 1979) 2021 Jun 11;135(11):1409-1426
Clinical science (London, England : 1979) 2021 Jun 11;135(11):1409-1426
Renoprotective effects of levosimendan on acute kidney injury following cardiac arrest via anti-inflammation, anti-apoptosis, and ERK activation.
Tian L, Wang S, Zhao L, Lu X, Zhu C, Gong H, Yang W
FEBS open bio 2021 Jun 11;
FEBS open bio 2021 Jun 11;
Selenium Status in Diet Affects Acetaminophen-Induced Hepatotoxicity via Interruption of Redox Environment.
Li J, Cheng P, Li S, Zhao P, Han B, Ren X, Zhong JL, Lloyd MD, Pourzand C, Holmgren A, Lu J
Antioxidants & redox signaling 2021 Jun 10;34(17):1355-1367
Antioxidants & redox signaling 2021 Jun 10;34(17):1355-1367
STAT1 epigenetically regulates LCP2 and TNFAIP2 by recruiting EP300 to contribute to the pathogenesis of inflammatory bowel disease.
Yu YL, Chen M, Zhu H, Zhuo MX, Chen P, Mao YJ, Li LY, Zhao Q, Wu M, Ye M
Clinical epigenetics 2021 Jun 10;13(1):127
Clinical epigenetics 2021 Jun 10;13(1):127
Reducing lipofuscin accumulation and cardiomyocytic senescence of aging heart by enhancing autophagy.
Li WW, Wang HJ, Tan YZ, Wang YL, Yu SN, Li ZH
Experimental cell research 2021 Jun 1;403(1):112585
Experimental cell research 2021 Jun 1;403(1):112585
Tumors exploit FTO-mediated regulation of glycolytic metabolism to evade immune surveillance.
Liu Y, Liang G, Xu H, Dong W, Dong Z, Qiu Z, Zhang Z, Li F, Huang Y, Li Y, Wu J, Yin S, Zhang Y, Guo P, Liu J, Xi JJ, Jiang P, Han D, Yang CG, Xu MM
Cell metabolism 2021 Jun 1;33(6):1221-1233.e11
Cell metabolism 2021 Jun 1;33(6):1221-1233.e11
A kinome screen reveals that Nemo-like kinase is a key suppressor of hepatic gluconeogenesis.
Ji YX, Wang Y, Li PL, Cai L, Wang XM, Bai L, Liu Z, Tian H, Tian S, Zhang P, Zhang XJ, Cheng X, Yuan Y, She ZG, Hu Y, Li H
Cell metabolism 2021 Jun 1;33(6):1171-1186.e9
Cell metabolism 2021 Jun 1;33(6):1171-1186.e9
VEGF/Src signaling mediated pleural barrier damage and increased permeability contributes to subpleural pulmonary fibrosis.
Lu YZ, Liang LM, Cheng PP, Xiong L, Wang M, Song LJ, Yu F, He XL, Xiong L, Wang XR, Xin JB, Ye H, Ma WL
American journal of physiology. Lung cellular and molecular physiology 2021 Jun 1;320(6):L990-L1004
American journal of physiology. Lung cellular and molecular physiology 2021 Jun 1;320(6):L990-L1004
High uric acid induces liver fat accumulation via ROS/JNK/AP-1 signaling.
Xie, Zhao H, Lu J, He F, Liu W, Yu W, Wang Q, Hisatome I, Yamamoto T, Koyama H, Cheng J
American journal of physiology. Endocrinology and metabolism 2021 Jun 1;320(6):E1032-E1043
American journal of physiology. Endocrinology and metabolism 2021 Jun 1;320(6):E1032-E1043
THAP11 down-regulation may contribute to cardio-protective effects of sevoflurane anesthesia: Evidence from clinical and molecular evidence.
Duan Z, Zhou X, Chen F, Chen H, Duan G, Li H
Life sciences 2021 Jun 1;274:119327
Life sciences 2021 Jun 1;274:119327
Nicotinamide mononucleotide attenuates isoproterenol-induced cardiac fibrosis by regulating oxidative stress and Smad3 acetylation.
Wu K, Li B, Lin Q, Xu W, Zuo W, Li J, Liu N, Tu T, Zhang B, Xiao Y, Liu Q
Life sciences 2021 Jun 1;274:119299
Life sciences 2021 Jun 1;274:119299
MIR29A Impedes Metastatic Behaviors in Hepatocellular Carcinoma via Targeting LOX, LOXL2, and VEGFA.
Yang YL, Tsai MC, Chang YH, Wang CC, Chu PY, Lin HY, Huang YH
International journal of molecular sciences 2021 Jun 1;22(11)
International journal of molecular sciences 2021 Jun 1;22(11)
Inducible ATP1B1 Upregulates Antiviral Innate Immune Responses by the Ubiquitination of TRAF3 and TRAF6.
Cao W, Guo Y, Cheng Z, Xu G, Zuo Q, Nie L, Huang Y, Liu S, Zhu Y
Journal of immunology (Baltimore, Md. : 1950) 2021 Jun 1;206(11):2668-2681
Journal of immunology (Baltimore, Md. : 1950) 2021 Jun 1;206(11):2668-2681
Microglial IL-10 and β-endorphin expression mediates gabapentinoids antineuropathic pain.
Ahmad KA, Shoaib RM, Ahsan MZ, Deng MY, Ma L, Apryani E, Li XY, Wang YX
Brain, behavior, and immunity 2021 Jul;95:344-361
Brain, behavior, and immunity 2021 Jul;95:344-361
Expression of Cntn1 is regulated by stress and associated with anxiety and depression phenotypes.
Li S, Cao W, Zhou S, Ma M, Zhang W, Li F, Li C
Brain, behavior, and immunity 2021 Jul;95:142-153
Brain, behavior, and immunity 2021 Jul;95:142-153
GCH1 induces immunosuppression through metabolic reprogramming and IDO1 upregulation in triple-negative breast cancer.
Wei JL, Wu SY, Yang YS, Xiao Y, Jin X, Xu XE, Hu X, Li DQ, Jiang YZ, Shao ZM
Journal for immunotherapy of cancer 2021 Jul;9(7)
Journal for immunotherapy of cancer 2021 Jul;9(7)
LXRβ is involved in the control of platelet production from megakaryocytes.
Wan YW, Liu W, Feng MT, Pu J, Zhuang SW, He B, Liu X
Blood cells, molecules & diseases 2021 Jul;89:102568
Blood cells, molecules & diseases 2021 Jul;89:102568
Wireless Localized Electrical Stimulation Generated by an Ultrasound-Driven Piezoelectric Discharge Regulates Proinflammatory Macrophage Polarization.
Kong Y, Liu F, Ma B, Duan J, Yuan W, Sang Y, Han L, Wang S, Liu H
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2021 Jul;8(13):2100962
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2021 Jul;8(13):2100962
Multiregional profiling of the brain transmembrane proteome uncovers novel regulators of depression.
Li S, Luo H, Lou R, Tian C, Miao C, Xia L, Pan C, Duan X, Dang T, Li H, Fan C, Tang P, Zhang Z, Liu Y, Li Y, Xu F, Zhang Y, Zhong G, Hu J, Shui W
Science advances 2021 Jul;7(30)
Science advances 2021 Jul;7(30)
Sulforaphane Balances Ca2+ Homeostasis Injured by Excessive Fat via Mitochondria-Associated Membrane (MAM).
Tian S, Lei P, Zhang J, Sun Y, Li B, Shan Y
Molecular nutrition & food research 2021 Jul;65(14):e2001076
Molecular nutrition & food research 2021 Jul;65(14):e2001076
Enhancing immunogenicity of HPV16 E7 DNA vaccine by conjugating codon-optimized GM-CSF to HPV16 E7 DNA.
Chen YP, Lin CC, Xie YX, Chen CY, Qiu JT
Taiwanese journal of obstetrics & gynecology 2021 Jul;60(4):700-705
Taiwanese journal of obstetrics & gynecology 2021 Jul;60(4):700-705
The LncRNA RP11-279C4.1 Enhances the Malignant Behaviour of Glioma Cells and Glioma Stem-Like Cells by Regulating the miR-1273g-3p/CBX3 Axis.
Wang F, Zhang L, Luo Y, Zhang Q, Zhang Y, Shao Y, Yuan L
Molecular neurobiology 2021 Jul;58(7):3362-3373
Molecular neurobiology 2021 Jul;58(7):3362-3373
Generation of a TLR2 homozygous knockout human embryonic stem cell line WAe001-A-64 using CRISPR/Cas9 editing.
Getachew A, Yang Z, Huang X, Wu F, Liu YY, Yan C, Yang F, Li Y
Stem cell research 2021 Jul;54:102401
Stem cell research 2021 Jul;54:102401
Neutrophil extracellular traps promote gastric cancer metastasis by inducing epithelial‑mesenchymal transition.
Zhu T, Zou X, Yang C, Li L, Wang B, Li R, Li H, Xu Z, Huang D, Wu Q
International journal of molecular medicine 2021 Jul;48(1)
International journal of molecular medicine 2021 Jul;48(1)
Selenium triggers Nrf2-AMPK crosstalk to alleviate cadmium-induced autophagy in rabbit cerebrum.
Xue H, Cao H, Xing C, Feng J, Zhang L, Zhang C, Hu G, Yang F
Toxicology 2021 Jul;459:152855
Toxicology 2021 Jul;459:152855
EZH2 regulates expression of FOXC1 by mediating H3K27me3 in breast cancers.
Zheng XJ, Li W, Yi J, Liu JY, Ren LW, Zhu XM, Liu SW, Wang JH, Du GH
Acta pharmacologica Sinica 2021 Jul;42(7):1171-1179
Acta pharmacologica Sinica 2021 Jul;42(7):1171-1179
Exosomes are involved in total body irradiation-induced intestinal injury in mice.
Li H, Jiang M, Zhao SY, Zhang SQ, Lu L, He X, Feng GX, Wu X, Fan SJ
Acta pharmacologica Sinica 2021 Jul;42(7):1111-1123
Acta pharmacologica Sinica 2021 Jul;42(7):1111-1123
YB1 regulates miR-205/200b-ZEB1 axis by inhibiting microRNA maturation in hepatocellular carcinoma.
Liu X, Chen D, Chen H, Wang W, Liu Y, Wang Y, Duan C, Ning Z, Guo X, Otkur W, Liu J, Qi H, Liu X, Lin A, Xia T, Liu HX, Piao HL
Cancer communications (London, England) 2021 Jul;41(7):576-595
Cancer communications (London, England) 2021 Jul;41(7):576-595
A multifaceted role of progranulin in regulating amyloid-beta dynamics and responses.
Du H, Wong MY, Zhang T, Santos MN, Hsu C, Zhang J, Yu H, Luo W, Hu F
Life science alliance 2021 Jul;4(7)
Life science alliance 2021 Jul;4(7)
MiR-706 alleviates white matter injury via downregulating PKCα/MST1/NF-κB pathway after subarachnoid hemorrhage in mice.
Ru X, Qu J, Li Q, Zhou J, Huang S, Li W, Zuo S, Chen Y, Liu Z, Feng H
Experimental neurology 2021 Jul;341:113688
Experimental neurology 2021 Jul;341:113688
Direct control of store-operated calcium channels by ultrafast laser.
Cheng P, Tian X, Tang W, Cheng J, Bao J, Wang H, Zheng S, Wang Y, Wei X, Chen T, Feng H, Xue T, Goda K, He H
Cell research 2021 Jul;31(7):758-772
Cell research 2021 Jul;31(7):758-772
Aflatoxin B1 inhibited autophagy flux by inducing lysosomal alkalinization in HepG2 cells.
Zhang Q, Feng Z, Lu J, Lu J, Guan S, Chen Y
Toxicology mechanisms and methods 2021 Jul;31(6):450-456
Toxicology mechanisms and methods 2021 Jul;31(6):450-456
MicroRNA-215-5p inhibits the proliferation of keratinocytes and alleviates psoriasis-like inflammation by negatively regulating DYRK1A and its downstream signalling pathways.
Liu A, Zhang B, Zhao W, Tu Y, Wang Q, Li J
Experimental dermatology 2021 Jul;30(7):932-942
Experimental dermatology 2021 Jul;30(7):932-942
Mechanistic insights into mitochondrial tRNAAla 3'-end metabolism deficiency.
Ji Y, Nie Z, Meng F, Hu C, Chen H, Jin L, Chen M, Zhang M, Zhang J, Liang M, Wang M, Guan MX
The Journal of biological chemistry 2021 Jul;297(1):100816
The Journal of biological chemistry 2021 Jul;297(1):100816
MACF1 promotes osteoblast differentiation by sequestering repressors in cytoplasm.
Hu L, Yin C, Chen D, Wu Z, Liang S, Zhang Y, Huang Z, Liu S, Xu X, Chen Z, Zhang Y, Qian A
Cell death and differentiation 2021 Jul;28(7):2160-2178
Cell death and differentiation 2021 Jul;28(7):2160-2178
Overexpression of SERPINA3 promotes tumor invasion and migration, epithelial-mesenchymal-transition in triple-negative breast cancer cells.
Zhang Y, Tian J, Qu C, Peng Y, Lei J, Li K, Zong B, Sun L, Liu S
Breast cancer (Tokyo, Japan) 2021 Jul;28(4):859-873
Breast cancer (Tokyo, Japan) 2021 Jul;28(4):859-873
Human umbilical cord mesenchymal stem cell-derived exosomes inhibit migration and invasion of breast cancer cells via miR-21-5p/ZNF367 pathway.
Du L, Tao X, Shen X
Breast cancer (Tokyo, Japan) 2021 Jul;28(4):829-837
Breast cancer (Tokyo, Japan) 2021 Jul;28(4):829-837
Caspase-1 inhibits IFN-β production via cleavage of cGAS during M. bovis infection.
Liao Y, Liu C, Wang J, Song Y, Sabir N, Hussain T, Yao J, Luo L, Wang H, Cui Y, Yang L, Zhao D, Zhou X
Veterinary microbiology 2021 Jul;258:109126
Veterinary microbiology 2021 Jul;258:109126
METTL16 promotes cell proliferation by up-regulating cyclin D1 expression in gastric cancer.
Wang XK, Zhang YW, Wang CM, Li B, Zhang TZ, Zhou WJ, Cheng LJ, Huo MY, Zhang CH, He YL
Journal of cellular and molecular medicine 2021 Jul;25(14):6602-6617
Journal of cellular and molecular medicine 2021 Jul;25(14):6602-6617
Different roles of BAG3 in cardiac physiological hypertrophy and pathological remodeling.
Jia P, Wu N, Yang H, Guo Y, Guo X, Sun Y
Translational research : the journal of laboratory and clinical medicine 2021 Jul;233:47-61
Translational research : the journal of laboratory and clinical medicine 2021 Jul;233:47-61
Cancer cell-intrinsic STING is associated with CD8 + T-cell infiltration and might serve as a potential immunotherapeutic target in hepatocellular carcinoma.
Zhang Y, Zhai Q, Feng X, Chen D, Lu Y, Hu J, Xie H, Zhou L, Wu J, Zheng S
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 2021 Jul;23(7):1314-1324
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 2021 Jul;23(7):1314-1324
Effects of TRIM59 on RAW264.7 macrophage gene expression and function.
Jin Z, Zhu Z, Zhang W, Liu L, Tang M, Li D, Yan D, Zhu X
Immunobiology 2021 Jul;226(4):152109
Immunobiology 2021 Jul;226(4):152109
Mechanism of validamycin A inhibiting DON biosynthesis and synergizing with DMI fungicides against Fusarium graminearum.
Bian C, Duan Y, Xiu Q, Wang J, Tao X, Zhou M
Molecular plant pathology 2021 Jul;22(7):769-785
Molecular plant pathology 2021 Jul;22(7):769-785
Effect of the interference with DRP1 expression on the biological characteristics of glioma stem cells.
Zhang L, Cao H, Tao H, Yang J, Gong W, Hu Q
Experimental and therapeutic medicine 2021 Jul;22(1):696
Experimental and therapeutic medicine 2021 Jul;22(1):696
C1orf61 promotes hepatocellular carcinoma metastasis and increases the therapeutic response to sorafenib.
Yu Y, Wang Z, Huang Z, Tang X, Huang X, Li W
Biochimica et biophysica acta. Molecular cell research 2021 Jul;1868(8):119048
Biochimica et biophysica acta. Molecular cell research 2021 Jul;1868(8):119048
Activation of Ca2+/Calmodulin-Dependent Protein Kinase II (CaMKII) with Lidocaine Provokes Pyroptosis of Glioblastoma Cells.
Zhou B, Lin Y, Chen S, Cai J, Luo Z, Yu S, Lu J
Bulletin of experimental biology and medicine 2021 Jul;171(3):297-304
Bulletin of experimental biology and medicine 2021 Jul;171(3):297-304
SNX17 protects the heart from doxorubicin-induced cardiotoxicity by modulating LMOD2 degradation.
Zhang Y, Ni L, Lin B, Hu L, Lin Z, Yang J, Wang J, Ma H, Liu Y, Yang J, Lin J, Xu L, Wu L, Shi D
Pharmacological research 2021 Jul;169:105642
Pharmacological research 2021 Jul;169:105642
Dihydrotanshinone I inhibits aortic valve interstitial cell calcification via the SMAD1/5/8/NF-κB/ERK pathway.
Wang Y, Weng Y, Li X, Huang Q, Xiang Y, Li X, Shi Q
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Jul;139:111674
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Jul;139:111674
Fucoxanthin rescues dexamethasone induced C2C12 myotubes atrophy.
Zhiyin L, Jinliang C, Qiunan C, Yunfei Y, Qian X
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Jul;139:111590
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Jul;139:111590
Tacrolimus inhibits oral carcinogenesis through cell cycle control.
Li Y, Wang Y, Li J, Ling Z, Chen W, Zhang L, Hu Q, Wu T, Cheng B, Wang Y, Xia J
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Jul;139:111545
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Jul;139:111545
Choline attenuates heat stress-induced oxidative injury and apoptosis in bovine mammary epithelial cells by modulating PERK/Nrf-2 signaling pathway.
Yang M, Kuang M, Wang G, Ali I, Tang Y, Yang C, Li Y, Li L
Molecular immunology 2021 Jul;135:388-397
Molecular immunology 2021 Jul;135:388-397
Brevilin A inhibits NLRP3 inflammasome activation in vivo and in vitro by acting on the upstream of NLRP3-induced ASC oligomerization.
Qin Q, Xu G, Zhan X, Wang Z, Wang Y, Liu H, Hou X, Shi W, Ma J, Bai Z, Xiao X
Molecular immunology 2021 Jul;135:116-126
Molecular immunology 2021 Jul;135:116-126
ASAP1 regulates the uptake of Mycobacterium tuberculosis H37Ra in THP1-derived macrophages by remodeling actin cytoskeleton.
Cui J, Chen G, Zhao Z, Wang L, Wen D, Xing L, Wu C
Tuberculosis (Edinburgh, Scotland) 2021 Jul;129:102090
Tuberculosis (Edinburgh, Scotland) 2021 Jul;129:102090
Calycosin attenuates pulmonary fibrosis by the epithelial-mesenchymal transition repression upon inhibiting the AKT/GSK3β/β-catenin signaling pathway.
Liu X, Shao Y, Zhang X, Ji X, Xie M, Liu H
Acta histochemica 2021 Jul;123(5):151746
Acta histochemica 2021 Jul;123(5):151746
KIN17 promotes tumor metastasis by activating EMT signaling in luminal-A breast cancer.
Huang Q, Zahid KR, Chen J, Pang X, Zhong M, Huang H, Pan W, Yin J, Raza U, Zeng J, Zhu X, Zeng T
Thoracic cancer 2021 Jul;12(13):2013-2023
Thoracic cancer 2021 Jul;12(13):2013-2023
C188-9 reduces TGF-β1-induced fibroblast activation and alleviates ISO-induced cardiac fibrosis in mice.
Liu J, Jin Y, Wang B, Zhang J, Zuo S
FEBS open bio 2021 Jul;11(7):2033-2040
FEBS open bio 2021 Jul;11(7):2033-2040
Protective effects of VMY-2-95 on corticosterone-induced injuries in mice and cellular models.
Yu Z, Kong D, Liang Y, Zhao X, Du G
Acta pharmaceutica Sinica. B 2021 Jul;11(7):1903-1913
Acta pharmaceutica Sinica. B 2021 Jul;11(7):1903-1913
miRNA-194 predicts favorable prognosis in gastric cancer and inhibits gastric cancer cell growth by targeting CCND1.
Wang J, Zhang M, Hu X, She J, Sun R, Qin S, Li D
FEBS open bio 2021 Jul;11(7):1814-1826
FEBS open bio 2021 Jul;11(7):1814-1826
Tubeimoside I improves endothelial function in sepsis via activation of SIRT3.
Yang X, Li X, Luo M, Li C, Huang L, Li X, Huang B, Shen J, Luo S, Yan J
Laboratory investigation; a journal of technical methods and pathology 2021 Jul;101(7):897-907
Laboratory investigation; a journal of technical methods and pathology 2021 Jul;101(7):897-907
The Sonic Hedgehog signaling pathway regulates autophagy and migration in ovarian cancer.
Pan Y, Zhou J, Zhang W, Yan L, Lu M, Dai Y, Zhou H, Zhang S, Yang J
Cancer medicine 2021 Jul;10(13):4510-4521
Cancer medicine 2021 Jul;10(13):4510-4521
Discovery of β-Carboline Derivatives as a Highly Potent Cardioprotectant against Myocardial Ischemia-Reperfusion Injury.
Zhang H, Zhang RH, Liao XM, Yang D, Wang YC, Zhao YL, Xu GB, Liu CH, Li YJ, Liao SG, Zhou M
Journal of medicinal chemistry 2021 Jul 8;64(13):9166-9181
Journal of medicinal chemistry 2021 Jul 8;64(13):9166-9181
YBX1 is required for maintaining myeloid leukemia cell survival by regulating BCL2 stability in an m6A-dependent manner.
Feng M, Xie X, Han G, Zhang T, Li Y, Li Y, Yin R, Wang Q, Zhang T, Wang P, Hu J, Cheng Y, Gao Z, Wang J, Chang J, Cui M, Gao K, Chai J, Liu W, Guo C, Li S, Liu L, Zhou F, Chen J, Zhang H
Blood 2021 Jul 8;138(1):71-85
Blood 2021 Jul 8;138(1):71-85
Intestinal Klebsiella pneumoniae infection enhances susceptibility to epileptic seizure which can be reduced by microglia activation.
Lin P, Lin A, Tao K, Yang M, Ye Q, Chen H, Chen Y, Ma Y, Lin Z, He M, Wang X, Tian X
Cell death discovery 2021 Jul 7;7(1):175
Cell death discovery 2021 Jul 7;7(1):175
Inhibition of xCT suppresses the efficacy of anti-PD-1/L1 melanoma treatment through exosomal PD-L1-induced macrophage M2 polarization.
Liu N, Zhang J, Yin M, Liu H, Zhang X, Li J, Yan B, Guo Y, Zhou J, Tao J, Hu S, Chen X, Peng C
Molecular therapy : the journal of the American Society of Gene Therapy 2021 Jul 7;29(7):2321-2334
Molecular therapy : the journal of the American Society of Gene Therapy 2021 Jul 7;29(7):2321-2334
The cardiac translational landscape reveals that micropeptides are new players involved in cardiomyocyte hypertrophy.
Yan Y, Tang R, Li B, Cheng L, Ye S, Yang T, Han YC, Liu C, Dong Y, Qu LH, Lui KO, Yang JH, Huang ZP
Molecular therapy : the journal of the American Society of Gene Therapy 2021 Jul 7;29(7):2253-2267
Molecular therapy : the journal of the American Society of Gene Therapy 2021 Jul 7;29(7):2253-2267
Prognostic signature composed of transcription factors accurately predicts the prognosis of gastric cancer patients.
Zhou L, Chen Z, Wu Y, Lu H, Xin L
Cancer cell international 2021 Jul 7;21(1):357
Cancer cell international 2021 Jul 7;21(1):357
Participation of Mind Bomb-2 in Sevoflurane Anesthesia Induces Cognitive Impairment in Aged Mice via Modulating Ferroptosis.
Zhao L, Gong H, Huang H, Tuerhong G, Xia H
ACS chemical neuroscience 2021 Jul 7;12(13):2399-2408
ACS chemical neuroscience 2021 Jul 7;12(13):2399-2408
USP19 promotes hypoxia-induced mitochondrial division via FUNDC1 at ER-mitochondria contact sites.
Chai P, Cheng Y, Hou C, Yin L, Zhang D, Hu Y, Chen Q, Zheng P, Teng J, Chen J
The Journal of cell biology 2021 Jul 5;220(7)
The Journal of cell biology 2021 Jul 5;220(7)
Identification and optimization of 3-bromo-N'-(4-hydroxybenzylidene)-4-methylbenzohydrazide derivatives as mTOR inhibitors that induce autophagic cell death and apoptosis in triple-negative breast cancer.
Xu T, Zhang J, Yang C, Pluta R, Wang G, Ye T, Ouyang L
European journal of medicinal chemistry 2021 Jul 5;219:113424
European journal of medicinal chemistry 2021 Jul 5;219:113424
The intrinsic role and mechanism of tumor expressed-CD38 on lung adenocarcinoma progression.
Gao L, Liu Y, Du X, Ma S, Ge M, Tang H, Han C, Zhao X, Liu Y, Shao Y, Wu Z, Zhang L, Meng F, Xiao-Feng Qin F
Cell death & disease 2021 Jul 5;12(7):680
Cell death & disease 2021 Jul 5;12(7):680
A flavonoid-rich Smilax china L. extract prevents obesity by upregulating the adiponectin-receptor/AMPK signalling pathway and modulating the gut microbiota in mice.
Li X, Yang L, Li J, Lin L, Zheng G
Food & function 2021 Jul 5;12(13):5862-5875
Food & function 2021 Jul 5;12(13):5862-5875
Lnc-STYK1-2 regulates bladder cancer cell proliferation, migration, and invasion by targeting miR-146b-5p expression and AKT/STAT3/NF-kB signaling.
Dai R, Jiang Q, Zhou Y, Lin R, Lin H, Zhang Y, Zhang J, Gao X
Cancer cell international 2021 Jul 31;21(1):408
Cancer cell international 2021 Jul 31;21(1):408
Integrated bioinformatics analysis revealed the regulation of angiogenesis by tumor cells in hepatocellular carcinoma.
Huo M, Yu K, Zheng Y, Liu L, Zhao H, Li X, Huang C, Zhang J
Bioscience reports 2021 Jul 30;41(7)
Bioscience reports 2021 Jul 30;41(7)
Anti-anemia drug FG4592 retards the AKI-to-CKD transition by improving vascular regeneration and antioxidative capability.
Wu M, Chen W, Miao M, Jin Q, Zhang S, Bai M, Fan J, Zhang Y, Zhang A, Jia Z, Huang S
Clinical science (London, England : 1979) 2021 Jul 30;135(14):1707-1726
Clinical science (London, England : 1979) 2021 Jul 30;135(14):1707-1726
Glycoursodeoxycholic acid ameliorates diet-induced metabolic disorders with inhibiting endoplasmic reticulum stress.
Cheng L, Chen T, Guo M, Liu P, Qiao X, Wei Y, She J, Li B, Xi W, Zhou J, Yuan Z, Wu Y, Liu J
Clinical science (London, England : 1979) 2021 Jul 30;135(14):1689-1706
Clinical science (London, England : 1979) 2021 Jul 30;135(14):1689-1706
Propofol differentially induces unconsciousness and respiratory depression through distinct interactions between GABAA receptor and GABAergic neuron in corresponding nuclei.
Jiang J, Jiao Y, Gao P, Yin W, Zhou W, Zhang Y, Liu Y, Wen D, Wang Y, Zhou L, Yu T, Yu W
Acta biochimica et biophysica Sinica 2021 Jul 28;53(8):1076-1087
Acta biochimica et biophysica Sinica 2021 Jul 28;53(8):1076-1087
TBN improves motor function and prolongs survival in a TDP-43M337V mouse model of ALS.
Huang C, Li J, Zhang G, Lin Y, Li C, Zheng X, Song X, Han B, Guo B, Tu Z, Zhang J, Sun Y, Wang Y, Zhang Z, Yan S
Human molecular genetics 2021 Jul 28;30(16):1484-1496
Human molecular genetics 2021 Jul 28;30(16):1484-1496
Pterostilbene alleviates pulmonary fibrosis by regulating ASIC2.
Peng Y, Zhang Y, Zhang Y, Wang X, Xia Y
Chinese medicine 2021 Jul 28;16(1):66
Chinese medicine 2021 Jul 28;16(1):66
Analysis of the Internal Hypoxic Environment in Solid Tumor Tissue Using a Folding Paper System.
Huang CH, Chong KY, Lei KF
ACS applied materials & interfaces 2021 Jul 28;13(29):33885-33893
ACS applied materials & interfaces 2021 Jul 28;13(29):33885-33893
The anti-dysenteric drug fraxetin enhances anti-tumor efficacy of gemcitabine and suppresses pancreatic cancer development by antagonizing STAT3 activation.
Guo Y, Xiao Y, Guo H, Zhu H, Chen D, Wang J, Deng J, Lan J, Liu X, Zhang Q, Bai Y
Aging 2021 Jul 28;13(14):18545-18563
Aging 2021 Jul 28;13(14):18545-18563
MINDY1 promotes bladder cancer progression by stabilizing YAP.
Luo Y, Zhou J, Tang J, Zhou F, He Z, Liu T, Liu T
Cancer cell international 2021 Jul 27;21(1):395
Cancer cell international 2021 Jul 27;21(1):395
Serum exosomes from young rats improve the reduced osteogenic differentiation of BMSCs in aged rats with osteoporosis after fatigue loading in vivo.
Xun J, Li C, Liu M, Mei Y, Zhou Q, Wu B, Xie F, Liu Y, Dai R
Stem cell research & therapy 2021 Jul 27;12(1):424
Stem cell research & therapy 2021 Jul 27;12(1):424
Tree Shrew Cells Transduced with Human CD4 and CCR5 Support Early Steps of HIV-1 Replication, but Viral Infectivity Is Restricted by APOBEC3.
Luo MT, Mu D, Yang X, Luo RH, Zheng HY, Chen M, Guo YQ, Zheng YT
Journal of virology 2021 Jul 26;95(16):e0002021
Journal of virology 2021 Jul 26;95(16):e0002021
GNAI2 Promotes Proliferation and Decreases Apoptosis in Rabbit Melanocytes.
Hu S, Dai Y, Bai S, Zhao B, Wu X, Chen Y
Genes 2021 Jul 25;12(8)
Genes 2021 Jul 25;12(8)
Behavioral effects of early-life exposure to perfluorooctanoic acid might synthetically link to multiple aspects of dopaminergic neuron development and dopamine functions in zebrafish larvae.
Yu T, Zhou G, Cai Z, Liang W, Du Y, Wang W
Aquatic toxicology (Amsterdam, Netherlands) 2021 Jul 24;238:105926
Aquatic toxicology (Amsterdam, Netherlands) 2021 Jul 24;238:105926
Phenethylamine in chlorella alleviates high-fat diet-induced mouse liver damage by regulating generation of methylglyoxal.
Zheng Y, Martin-Morales A, Wang J, Fujishima M, Okumura E, Sato K
NPJ science of food 2021 Jul 23;5(1):22
NPJ science of food 2021 Jul 23;5(1):22
A CREB1-miR-181a-5p loop regulates the pathophysiologic features of bone marrow stromal cells in fibrous dysplasia of bone.
Fu Y, Xin Z, Ling Z, Xie H, Xiao T, Shen X, Lin J, Xu L, Jiang H
Molecular medicine (Cambridge, Mass.) 2021 Jul 22;27(1):81
Molecular medicine (Cambridge, Mass.) 2021 Jul 22;27(1):81
Autophagy-related circRNA evaluation reveals hsa_circ_0001747 as a potential favorable prognostic factor for biochemical recurrence in patients with prostate cancer.
Zhong C, Wu K, Wang S, Long Z, Yang T, Zhong W, Tan X, Wang Z, Li C, Lu J, Mao X
Cell death & disease 2021 Jul 22;12(8):726
Cell death & disease 2021 Jul 22;12(8):726
Role of MCP-1 and IL-8 in viral anterior uveitis, and contractility and fibrogenic activity of trabecular meshwork cells.
Lee J, Choi JA, Ju HH, Kim JE, Paik SY, Rao PV
Scientific reports 2021 Jul 22;11(1):14950
Scientific reports 2021 Jul 22;11(1):14950
Epitranscriptomic editing of the RNA N6-methyladenosine modification by dCasRx conjugated methyltransferase and demethylase.
Xia Z, Tang M, Ma J, Zhang H, Gimple RC, Prager BC, Tang H, Sun C, Liu F, Lin P, Mei Y, Du R, Rich JN, Xie Q
Nucleic acids research 2021 Jul 21;49(13):7361-7374
Nucleic acids research 2021 Jul 21;49(13):7361-7374
Lactate secreted by PKM2 upregulation promotes Galectin-9-mediated immunosuppression via inhibiting NF-κB pathway in HNSCC.
Chang H, Xu Q, Li J, Li M, Zhang Z, Ma H, Yang X
Cell death & disease 2021 Jul 21;12(8):725
Cell death & disease 2021 Jul 21;12(8):725
SARS-CoV-2 Restructures the Host Chromatin Architecture.
Wang R, Lee JH, Xiong F, Kim J, Hasani LA, Yuan X, Shivshankar P, Krakowiak J, Qi C, Wang Y, Eltzschig HK, Li W
bioRxiv : the preprint server for biology 2021 Jul 21;
bioRxiv : the preprint server for biology 2021 Jul 21;
Comparable radiation sensitivity in p53 wild-type and p53 deficient tumor cells associated with different cell death modalities.
Li P, Liu X, Zhao T, Li F, Wang Q, Zhang P, Hirayama R, Chen W, Jin X, Zheng X, Wang Z, Li Q
Cell death discovery 2021 Jul 20;7(1):184
Cell death discovery 2021 Jul 20;7(1):184
A mesenchymal-like subpopulation in non-neuroendocrine SCLC contributes to metastasis.
Jin Y, Xiao T, Feng Y, Yang J, Guo C, Hu L, Ji H
Journal of genetics and genomics = Yi chuan xue bao 2021 Jul 20;48(7):571-581
Journal of genetics and genomics = Yi chuan xue bao 2021 Jul 20;48(7):571-581
TGF-β1-mediated exosomal lnc-MMP2-2 increases blood-brain barrier permeability via the miRNA-1207-5p/EPB41L5 axis to promote non-small cell lung cancer brain metastasis.
Wu D, Deng S, Li L, Liu T, Zhang T, Li J, Yu Y, Xu Y
Cell death & disease 2021 Jul 20;12(8):721
Cell death & disease 2021 Jul 20;12(8):721
Inactivation of the tumor suppressor p53 by long noncoding RNA RMRP.
Chen Y, Hao Q, Wang S, Cao M, Huang Y, Weng X, Wang J, Zhang Z, He X, Lu H, Zhou X
Proceedings of the National Academy of Sciences of the United States of America 2021 Jul 20;118(29)
Proceedings of the National Academy of Sciences of the United States of America 2021 Jul 20;118(29)
CaMKII and CaV3.2 T-type calcium channel mediate Connexin-43-dependent inflammation by activating astrocytes in vincristine-induced neuropathic pain.
Li GZ, Hu YH, Lu YN, Yang QY, Fu D, Chen F, Li YM
Cell biology and toxicology 2021 Jul 20;
Cell biology and toxicology 2021 Jul 20;
Variations in Env at amino acids 328 and 330 affect HIV-1 replicative fitness and entry inhibitor sensitivity.
Wang H, Li Y, Li Y, Li B, Zhu X, Yan D, Li M, Wu W, Sun M, Yang R
Virus research 2021 Jul 2;299:198424
Virus research 2021 Jul 2;299:198424
The molecular basis of coupling between poly(A)-tail length and translational efficiency.
Xiang K, Bartel DP
eLife 2021 Jul 2;10
eLife 2021 Jul 2;10
MARCH6 promotes hepatocellular carcinoma development through up-regulation of ATF2.
Sun J, Dong Z, Chang Z, Liu H, Jiang Q, Zhang D, Lu S, Jia X, Wu D, Ge A, Zhao P, Wang J, Lu Y
BMC cancer 2021 Jul 17;21(1):827
BMC cancer 2021 Jul 17;21(1):827
Erlotinib protests against LPS-induced parthanatos through inhibiting macrophage surface TLR4 expression.
Xue Q, Liu X, Chen C, Zhang X, Xie P, Liu Y, Zhou S, Tang J
Cell death discovery 2021 Jul 16;7(1):181
Cell death discovery 2021 Jul 16;7(1):181
BMI1 activates P-glycoprotein via transcription repression of miR-3682-3p and enhances chemoresistance of bladder cancer cell.
Chen MK, Zhou JH, Wang P, Ye YL, Liu Y, Zhou JW, Chen ZJ, Yang JK, Liao DY, Liang ZJ, Xie X, Zhou QZ, Xue KY, Guo WB, Xia M, Bao JM, Yang C, Duan HF, Wang HY, Huang ZP, Qin ZK, Liu CD
Aging 2021 Jul 16;13(14):18310-18330
Aging 2021 Jul 16;13(14):18310-18330
Role of NLR family pyrin domain-containing 3 inflammasome in the activation of pancreatic stellate cells.
Li CX, Cui LH, Zhang LQ, Yang L, Zhuo YZ, Cui NQ, Zhang SK
Experimental cell research 2021 Jul 15;404(2):112634
Experimental cell research 2021 Jul 15;404(2):112634
Chlamydia trachomatis Pgp3 protein regulates oxidative stress via activation of the Nrf2/NQO1 signal pathway.
Shu M, Lei W, Su S, Wen Y, Luo F, Zhao L, Chen L, Lu C, Zhou Z, Li Z
Life sciences 2021 Jul 15;277:119502
Life sciences 2021 Jul 15;277:119502
The mechanisms of action of WeiChang'An Pill (WCAP) treat diarrhoea-predominant irritable bowel syndrome (IBS-D) using network pharmacology approach and in vivo studies.
Chen Y, Chu F, Lin J, Su Z, Liao M, Li T, Li Y, Johnson N, Zheng H, Ding X
Journal of ethnopharmacology 2021 Jul 15;275:114119
Journal of ethnopharmacology 2021 Jul 15;275:114119
Proteomics analysis in the kidney of mice following oral feeding Realgar.
Zhang S, Li C, Feng T, Cao S, Zhou H, Li L, Hu Q, Mao X, Ji S
Journal of ethnopharmacology 2021 Jul 15;275:114118
Journal of ethnopharmacology 2021 Jul 15;275:114118
Identification and validation of an immune-related prognostic signature and key gene in papillary thyroid carcinoma.
Qin R, Li C, Wang X, Zhong Z, Sun C
Cancer cell international 2021 Jul 15;21(1):378
Cancer cell international 2021 Jul 15;21(1):378
Nonstructural Protein NSs Hampers Cellular Antiviral Response through LSm14A during Severe Fever with Thrombocytopenia Syndrome Virus Infection.
Zhang L, Fu Y, Zhang R, Guan Y, Jiang N, Zheng N, Wu Z
Journal of immunology (Baltimore, Md. : 1950) 2021 Jul 15;207(2):590-601
Journal of immunology (Baltimore, Md. : 1950) 2021 Jul 15;207(2):590-601
Role of IL-6-IL-27 Complex in Host Antiviral Immune Response.
Zuo Q, Cheng Z, Zhang G, Xia Y, Xu G, Cao W, Yang X, Fu Y, He R, Fang P, Guo Y, Nie L, Huang Y, Liu L, Zhan J, Liu S, Zhu Y
Journal of immunology (Baltimore, Md. : 1950) 2021 Jul 15;207(2):577-589
Journal of immunology (Baltimore, Md. : 1950) 2021 Jul 15;207(2):577-589
Protective effects and mechanisms of high-dose vitamin C on sepsis-associated cognitive impairment in rats.
Zhang N, Zhao W, Hu ZJ, Ge SM, Huo Y, Liu LX, Gao BL
Scientific reports 2021 Jul 15;11(1):14511
Scientific reports 2021 Jul 15;11(1):14511
Ubiquitin-specific protease 15 contributes to gastric cancer progression by regulating the Wnt/β-catenin signaling pathway.
Zhong M, Zhou L, Fang Z, Yao YY, Zou JP, Xiong JP, Xiang XJ, Deng J
World journal of gastroenterology 2021 Jul 14;27(26):4221-4235
World journal of gastroenterology 2021 Jul 14;27(26):4221-4235
LncRNA PCGEM1 induces proliferation and migration in non-small cell lung cancer cells through modulating the miR-590-3p/SOX11 axis.
Wen H, Feng H, Ma Q, Liang C
BMC pulmonary medicine 2021 Jul 14;21(1):234
BMC pulmonary medicine 2021 Jul 14;21(1):234
Cyclophilin A Inhibits Human Respiratory Syncytial Virus (RSV) Replication by Binding to RSV-N through Its PPIase Activity.
Liang W, Zhang Y, Li M, Al-Shaebi F, Li J, Zhang J, Wei L
Journal of virology 2021 Jul 12;95(15):e0056321
Journal of virology 2021 Jul 12;95(15):e0056321
S-Allylmercapto-N-acetylcysteine ameliorates elastase-induced chronic obstructive pulmonary disease in mice via regulating autophagy.
Zheng D, Wang J, Li G, An L, Qu Y, Zhang Q, Ye W, Zhao X, Zhao Z
Biochemical and biophysical research communications 2021 Jul 12;562:83-88
Biochemical and biophysical research communications 2021 Jul 12;562:83-88
YTHDF2 facilitates UBXN1 mRNA decay by recognizing METTL3-mediated m6A modification to activate NF-κB and promote the malignant progression of glioma.
Chai RC, Chang YZ, Chang X, Pang B, An SY, Zhang KN, Chang YH, Jiang T, Wang YZ
Journal of hematology & oncology 2021 Jul 10;14(1):109
Journal of hematology & oncology 2021 Jul 10;14(1):109
Repression of the AURKA-CXCL5 axis induces autophagic cell death and promotes radiosensitivity in non-small-cell lung cancer.
Wang J, Hu T, Wang Q, Chen R, Xie Y, Chang H, Cheng J
Cancer letters 2021 Jul 1;509:89-104
Cancer letters 2021 Jul 1;509:89-104
Epitranscriptomic addition of m6A regulates HIV-1 RNA stability and alternative splicing.
Tsai K, Bogerd HP, Kennedy EM, Emery A, Swanstrom R, Cullen BR
Genes & development 2021 Jul 1;35(13-14):992-1004
Genes & development 2021 Jul 1;35(13-14):992-1004
p55PIK deficiency and its NH2-terminal derivative inhibit inflammation and emphysema in COPD mouse model.
Wang T, Du X, Wang Z, Gu Y, Huang Q, Wu J, Zhan Y, Chen J, Xiao C, Xie J
American journal of physiology. Lung cellular and molecular physiology 2021 Jul 1;321(1):L159-L173
American journal of physiology. Lung cellular and molecular physiology 2021 Jul 1;321(1):L159-L173
GALNT2 promotes cell proliferation, migration, and invasion by activating the Notch/Hes1-PTEN-PI3K/Akt signaling pathway in lung adenocarcinoma.
Wang W, Sun R, Zeng L, Chen Y, Zhang N, Cao S, Deng S, Meng X, Yang S
Life sciences 2021 Jul 1;276:119439
Life sciences 2021 Jul 1;276:119439
IL37 overexpression inhibits autophagy and apoptosis induced by hepatic ischemia reperfusion injury via modulating AMPK/mTOR/ULLK1 signalling pathways.
Chen QS, Shen A, Dai JW, Li TT, Huang WF, Shi K, Deng Y, Pan L, Wei XF, Wu ZJ
Life sciences 2021 Jul 1;276:119424
Life sciences 2021 Jul 1;276:119424
Seneca Valley Virus 3C Protease Induces Pyroptosis by Directly Cleaving Porcine Gasdermin D.
Wen W, Li X, Wang H, Zhao Q, Yin M, Liu W, Chen H, Qian P
Journal of immunology (Baltimore, Md. : 1950) 2021 Jul 1;207(1):189-199
Journal of immunology (Baltimore, Md. : 1950) 2021 Jul 1;207(1):189-199
Long noncoding RNA BS-DRL1 modulates the DNA damage response and genome stability by interacting with HMGB1 in neurons.
Lou MM, Tang XQ, Wang GM, He J, Luo F, Guan MF, Wang F, Zou H, Wang JY, Zhang Q, Xu MJ, Shi QL, Shen LB, Ma GM, Wu Y, Zhang YY, Liang AB, Wang TH, Xiong LL, Wang J, Xu J, Wang WY
Nature communications 2021 Jul 1;12(1):4075
Nature communications 2021 Jul 1;12(1):4075
Toll-like receptor-2 gene knockout results in neurobehavioral dysfunctions and multiple brain structural and functional abnormalities in mice.
Hu Y, Sun X, Wang S, Zhou C, Lin L, Ding X, Han J, Zhou Y, Jin G, Wang Y, Zhang W, Shi H, Zhang Z, Yang X, Hua F
Brain, behavior, and immunity 2021 Jan;91:257-266
Brain, behavior, and immunity 2021 Jan;91:257-266
Hepatocyte growth factor mediates a novel form of hepatic stem/progenitor cell-induced tolerance in a rat xenogeneic liver rejection model.
Chen Q, You Y, Zhang Y, Zhang H, Bai L
International immunopharmacology 2021 Jan;90:107180
International immunopharmacology 2021 Jan;90:107180
MicroRNA-124-3p affects myogenic differentiation of adipose-derived stem cells by targeting Caveolin-1 during pelvic floor dysfunction in Sprague Dawley rats.
Chen H, Li Z, Lin M, Lv X, Wang J, Wei Q, Zhang Z, Li L
Annals of translational medicine 2021 Jan;9(2):161
Annals of translational medicine 2021 Jan;9(2):161
Repressing PDCD4 activates JNK/ABCG2 pathway to induce chemoresistance to fluorouracil in colorectal cancer cells.
Hu L, Liang Y, Wu K, Wang C, Zhang T, Peng R, Zou F
Annals of translational medicine 2021 Jan;9(2):114
Annals of translational medicine 2021 Jan;9(2):114
RNA-binding protein QKI suppresses breast cancer via RASA1/MAPK signaling pathway.
Cao Y, Chu C, Li X, Gu S, Zou Q, Jin Y
Annals of translational medicine 2021 Jan;9(2):104
Annals of translational medicine 2021 Jan;9(2):104
The Beneficial Role of Sunitinib in Tumor Immune Surveillance by Regulating Tumor PD-L1.
Li H, Kuang X, Liang L, Ye Y, Zhang Y, Li J, Ma F, Tao J, Lei G, Zhao S, Su J, Yang N, Peng C, Xu X, Hung MC, Han L, Liu H, Liu J, Chen X
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2021 Jan;8(2):2001596
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2021 Jan;8(2):2001596
Preventive effect of dioscin against monosodium urate-mediated gouty arthritis through inhibiting inflammasome NLRP3 and TLR4/NF-κB signaling pathway activation: an in vivo and in vitro study.
Han J, Shi G, Li W, Xie Y, Li F, Jiang D
Journal of natural medicines 2021 Jan;75(1):37-47
Journal of natural medicines 2021 Jan;75(1):37-47
ETV5 Regulates Hepatic Fatty Acid Metabolism Through PPAR Signaling Pathway.
Mao Z, Feng M, Li Z, Zhou M, Xu L, Pan K, Wang S, Su W, Zhang W
Diabetes 2021 Jan;70(1):214-226
Diabetes 2021 Jan;70(1):214-226
TBC1D3 promotes neural progenitor proliferation by suppressing the histone methyltransferase G9a.
Hou QQ, Xiao Q, Sun XY, Ju XC, Luo ZG
Science advances 2021 Jan;7(3)
Science advances 2021 Jan;7(3)
MicroRNA-489-3p Represses Hepatic Stellate Cells Activation by Negatively Regulating the JAG1/Notch3 Signaling Pathway.
Li J, Dong S, Ye M, Peng G, Luo J, Wang C, Wang J, Zhao Q, Chang Y, Wang H
Digestive diseases and sciences 2021 Jan;66(1):143-150
Digestive diseases and sciences 2021 Jan;66(1):143-150
FIGNL1 promotes non‑small cell lung cancer cell proliferation.
Li M, Rui Y, Peng W, Hu J, Jiang A, Yang Z, Huang L
International journal of oncology 2021 Jan;58(1):83-99
International journal of oncology 2021 Jan;58(1):83-99
Parthenolide inhibits the tumor characteristics of renal cell carcinoma.
Liu D, Han Y, Liu L, Ren X, Zhang H, Fan S, Qin T, Li L
International journal of oncology 2021 Jan;58(1):100-110
International journal of oncology 2021 Jan;58(1):100-110
Dysfunction of Shh signaling activates autophagy to inhibit trophoblast motility in recurrent miscarriage.
Pan Y, Yan L, Chen Q, Wei C, Dai Y, Tong X, Zhu H, Lu M, Zhang Y, Jin X, Zhang T, Lin X, Zhou F, Zhang S
Experimental & molecular medicine 2021 Jan;53(1):52-66
Experimental & molecular medicine 2021 Jan;53(1):52-66
Prostaglandin E2 serves a dual role in regulating the migration of dendritic cells.
Diao G, Huang J, Zheng X, Sun X, Tian M, Han J, Guo J
International journal of molecular medicine 2021 Jan;47(1):207-218
International journal of molecular medicine 2021 Jan;47(1):207-218
Avasimibe exerts anticancer effects on human glioblastoma cells via inducing cell apoptosis and cell cycle arrest.
Liu JY, Fu WQ, Zheng XJ, Li W, Ren LW, Wang JH, Yang C, Du GH
Acta pharmacologica Sinica 2021 Jan;42(1):97-107
Acta pharmacologica Sinica 2021 Jan;42(1):97-107
UHRF1 Knockdown Attenuates Cell Growth, Migration, and Invasion in Cutaneous Squamous Cell Carcinoma.
Li Q, Chu Z, Geng S
Cancer investigation 2021 Jan;39(1):84-97
Cancer investigation 2021 Jan;39(1):84-97
Flavonoid compound breviscapine suppresses human osteosarcoma Saos-2 progression property and induces apoptosis by regulating mitochondria-dependent pathway.
Wang Z, Li H, Yan J, Liu Y
Journal of biochemical and molecular toxicology 2021 Jan;35(1):e22633
Journal of biochemical and molecular toxicology 2021 Jan;35(1):e22633
Nucleolin regulates 14-3-3ζ mRNA and promotes cofilin phosphorylation to induce tunneling nanotube formation.
Dagar S, Pushpa K, Pathak D, Samaddar S, Saxena A, Banerjee S, Mylavarapu SVS
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 Jan;35(1):e21199
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 Jan;35(1):e21199
Mefunidone ameliorates diabetic kidney disease in STZ and db/db mice.
Jiang Y, Xie F, Lv X, Wang S, Liao X, Yu Y, Dai Q, Zhang Y, Meng J, Hu G, Peng Z, Tao L
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 Jan;35(1):e21198
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 Jan;35(1):e21198
Rapid antidepressant-like effect of Fructus Aurantii depends on cAMP-response element binding protein/Brain-derived neurotrophic facto by mediating synaptic transmission.
Wu L, Zhang T, Chen K, Lu C, Liu XF, Zhou JL, Huang YK, Yan H, Chen Y, Zhang CJ, Li JF, Shi SQ, Ren P, Huang X
Phytotherapy research : PTR 2021 Jan;35(1):404-414
Phytotherapy research : PTR 2021 Jan;35(1):404-414
Effects of Y Box Binding Protein-1 in Progression and Prognosis of Cholangiocarcinoma.
Chen Y, Jiang P, Tian F, Chen G, Peng T, Deng X, Li Z, Huang D, Zhu J, Zhen P, Xie C, Wang S
Journal of investigative surgery : the official journal of the Academy of Surgical Research 2021 Jan;34(1):55-63
Journal of investigative surgery : the official journal of the Academy of Surgical Research 2021 Jan;34(1):55-63
Long noncoding RNA LINC00460 promotes the progression of cervical cancer via regulation of the miR-361-3p/Gli1 axis.
Li F, Zhu W, Wang Z
Human cell 2021 Jan;34(1):229-237
Human cell 2021 Jan;34(1):229-237
Long noncoding RNA TSLNC8 enhances pancreatic cancer aggressiveness by regulating CTNNB1 expression via association with HuR.
Chai W, Liu R, Li F, Zhang Z, Lei B
Human cell 2021 Jan;34(1):165-176
Human cell 2021 Jan;34(1):165-176
Hemizygous deletion of Tbk1 worsens neuromuscular junction pathology in TDP-43G298S transgenic mice.
Sieverding K, Ulmer J, Bruno C, Satoh T, Tsao W, Freischmidt A, Akira S, Wong PC, Ludolph AC, Danzer KM, Lobsiger CS, Brenner D, Weishaupt JH
Experimental neurology 2021 Jan;335:113496
Experimental neurology 2021 Jan;335:113496
MiR-19b-3p accelerates bone loss after spinal cord injury by suppressing osteogenesis via regulating PTEN/Akt/mTOR signalling.
Liu D, Wang B, Qiu M, Huang Y
Journal of cellular and molecular medicine 2021 Jan;25(2):990-1000
Journal of cellular and molecular medicine 2021 Jan;25(2):990-1000
Maltol prevents the progression of osteoarthritis by targeting PI3K/Akt/NF-κB pathway: In vitro and in vivo studies.
Lu H, Fu C, Kong S, Wang X, Sun L, Lin Z, Luo P, Jin H
Journal of cellular and molecular medicine 2021 Jan;25(1):499-509
Journal of cellular and molecular medicine 2021 Jan;25(1):499-509
Mixed-lineage leukaemia 1 contributes to endometrial stromal cells progesterone responsiveness during decidualization.
Xiong Y, Wang Y, Ma L, Zhang Y, Qu X, Huang L, Wen X, Liu H, Zhang M, Zhang Y
Journal of cellular and molecular medicine 2021 Jan;25(1):297-308
Journal of cellular and molecular medicine 2021 Jan;25(1):297-308
Blocking VRK2 suppresses pulmonary adenocarcinoma progression via ERK1/2/AKT signal pathway by targeting miR-145-5p.
Mu Y, Liu WJ, Bie LY, Mu XQ, Zhao YQ
European review for medical and pharmacological sciences 2021 Jan;25(1):145-153
European review for medical and pharmacological sciences 2021 Jan;25(1):145-153
Treatment of keloids through Runx2 siRNA‑induced inhibition of the PI3K/AKT signaling pathway.
Lv W, Wu M, Ren Y, Luo X, Hu W, Zhang Q, Wu Y
Molecular medicine reports 2021 Jan;23(1)
Molecular medicine reports 2021 Jan;23(1)
Protection against Dextran Sulfate Sodium-Induced Ulcerative Colitis in Mice by Neferine, A Natural Product from Nelumbo nucifera Gaertn.
Min X, Guo Y, Zhou Y, Chen X
Cell journal 2021 Jan;22(4):523-531
Cell journal 2021 Jan;22(4):523-531
Effect of HMGB1 on monocyte immune function in respiratory syncytial virus bronchiolitis.
Niu M, Jiang Z, Xin X, Zhu J, Yang J, Diao M, Qi G, Qi B
Experimental and therapeutic medicine 2021 Jan;21(1):75
Experimental and therapeutic medicine 2021 Jan;21(1):75
miR-155-5p regulates macrophage M1 polarization and apoptosis in the synovial fluid of patients with knee osteoarthritis.
Li GS, Cui L, Wang GD
Experimental and therapeutic medicine 2021 Jan;21(1):68
Experimental and therapeutic medicine 2021 Jan;21(1):68
Contribution of DNA methyltransferases to spared nerve injury induced depression partially through epigenetically repressing Bdnf in hippocampus: Reversal by ketamine.
Liu R, Wu XM, He X, Wang RZ, Yin XY, Zhou F, Ji MH, Shen JC
Pharmacology, biochemistry, and behavior 2021 Jan;200:173079
Pharmacology, biochemistry, and behavior 2021 Jan;200:173079
Suppressed nuclear envelope proteins activate autophagy of vascular smooth muscle cells during cyclic stretch application.
Li HP, Liu JT, Chen YX, Wang WB, Han Y, Yao QP, Qi YX
Biochimica et biophysica acta. Molecular cell research 2021 Jan;1868(1):118855
Biochimica et biophysica acta. Molecular cell research 2021 Jan;1868(1):118855
Inhibition of proliferation-linked signaling cascades with atractylenolide I reduces myofibroblastic phenotype and renal fibrosis.
Guo Y, Xiao Y, Zhu H, Guo H, Zhou Y, Shentu Y, Zheng C, Chen C, Bai Y
Biochemical pharmacology 2021 Jan;183:114344
Biochemical pharmacology 2021 Jan;183:114344
P-glycoprotein deficiency enhances metabolic activation of and platelet response to clopidogrel through marked up-regulation of Cyp3a11 in mice: Direct evidence for the interplay between P-glycoprotein and Cyp3a.
Ji JZ, Li YF, Jiang LP, Tai T, Ge PX, Mi QY, Zhu T, Xie HG
Biochemical pharmacology 2021 Jan;183:114313
Biochemical pharmacology 2021 Jan;183:114313
NCBP3/SNHG6 inhibits GBX2 transcription in a histone modification manner to facilitate the malignant biological behaviour of glioma cells.
Li X, Zhang F, Ma J, Ruan X, Liu X, Zheng J, Liu Y, Cao S, Shen S, Shao L, Cai H, Li Z, Xue Y
RNA biology 2021 Jan;18(1):47-63
RNA biology 2021 Jan;18(1):47-63
Targeted inhibition of Rev-erb-α/β limits ferroptosis to ameliorate folic acid-induced acute kidney injury.
Guo L, Zhang T, Wang F, Chen X, Xu H, Zhou C, Chen M, Yu F, Wang S, Yang D, Wu B
British journal of pharmacology 2021 Jan;178(2):328-345
British journal of pharmacology 2021 Jan;178(2):328-345
The inhibition of colorectal cancer growth by the natural product macrocarpal I.
Qi L, Zhang Y, Zhang W, Wang Y, Han Y, Ding Y
Free radical biology & medicine 2021 Jan;162:383-391
Free radical biology & medicine 2021 Jan;162:383-391
HSF1 functions as a key defender against palmitic acid-induced ferroptosis in cardiomyocytes.
Wang N, Ma H, Li J, Meng C, Zou J, Wang H, Liu K, Liu M, Xiao X, Zhang H, Wang K
Journal of molecular and cellular cardiology 2021 Jan;150:65-76
Journal of molecular and cellular cardiology 2021 Jan;150:65-76
Exosome-mediated delivery of antisense oligonucleotides targeting α-synuclein ameliorates the pathology in a mouse model of Parkinson's disease.
Yang J, Luo S, Zhang J, Yu T, Fu Z, Zheng Y, Xu X, Liu C, Fan M, Zhang Z
Neurobiology of disease 2021 Jan;148:105218
Neurobiology of disease 2021 Jan;148:105218
Elevated ZBTB7A expression in the tumor invasive front correlates with more tumor budding formation in gastric adenocarcinoma.
Sun Y, He J, Shi DB, Zhang H, Chen X, Xing AY, Gao P
Journal of cancer research and clinical oncology 2021 Jan;147(1):105-115
Journal of cancer research and clinical oncology 2021 Jan;147(1):105-115
A SMOC2 variant inhibits BMP signaling by competitively binding to BMPR1B and causes growth plate defects.
Long F, Shi H, Li P, Guo S, Ma Y, Wei S, Li Y, Gao F, Gao S, Wang M, Duan R, Wang X, Yang K, Sun W, Li X, Li J, Liu Q
Bone 2021 Jan;142:115686
Bone 2021 Jan;142:115686
Melatonin increases the chemosensitivity of diffuse large B-cell lymphoma cells to epirubicin by inhibiting P-glycoprotein expression via the NF-κB pathway.
Liu K, Song J, Yan Y, Zou K, Che Y, Wang B, Li Z, Yu W, Guo W, Zou L, Deng W, Sun X
Translational oncology 2021 Jan;14(1):100876
Translational oncology 2021 Jan;14(1):100876
miRNA-146a-5p mitigates stress-induced premature senescence of D-galactose-induced primary thymic stromal cells.
Du H, Wang Y, Liu X, Wang S, Wu S, Yuan Z, Zhu X
Cytokine 2021 Jan;137:155314
Cytokine 2021 Jan;137:155314
CLDN10 associated with immune infiltration is a novel prognostic biomarker for clear cell renal cell carcinoma.
Yang W, Li L, Zhang K, Ma K, Gong Y, Zhou J, Gong K
Epigenomics 2021 Jan;13(1):31-45
Epigenomics 2021 Jan;13(1):31-45
Hyperglycemia-reduced NAD+ biosynthesis impairs corneal epithelial wound healing in diabetic mice.
Li Y, Li J, Zhao C, Yang L, Qi X, Wang X, Zhou Q, Shi W
Metabolism: clinical and experimental 2021 Jan;114:154402
Metabolism: clinical and experimental 2021 Jan;114:154402
NNT-induced tumor cell "slimming" reverses the pro-carcinogenesis effect of HIF2a in tumors.
Xiong Z, Xiong W, Xiao W, Yuan C, Shi J, Huang Y, Wang C, Meng X, Chen Z, Yang H, Chen K, Zhang X
Clinical and translational medicine 2021 Jan;11(1):e264
Clinical and translational medicine 2021 Jan;11(1):e264
Disrupted glucose homeostasis and skeletal-muscle-specific glucose uptake in an exocyst knockout mouse model.
Fujimoto BA, Young M, Nakamura N, Ha H, Carter L, Pitts MW, Torres D, Noh HL, Suk S, Kim JK, Polgar N
The Journal of biological chemistry 2021 Jan-Jun;296:100482
The Journal of biological chemistry 2021 Jan-Jun;296:100482
Determining the quantitative relationship between glycolysis and GAPDH in cancer cells exhibiting the Warburg effect.
Zhu X, Jin C, Pan Q, Hu X
The Journal of biological chemistry 2021 Jan-Jun;296:100369
The Journal of biological chemistry 2021 Jan-Jun;296:100369
Salvianolic acid B blocks hepatic stellate cell activation via FGF19/FGFR4 signaling.
Tian S, Chen M, Wang B, Han Y, Shang H, Chen J
Annals of hepatology 2021 Jan-Feb;20:100259
Annals of hepatology 2021 Jan-Feb;20:100259
Melatonin ameliorates hepatic steatosis by inhibiting NLRP3 inflammasome in db/db mice.
Yu Y, Chen D, Zhao Y, Zhu J, Dong X
International journal of immunopathology and pharmacology 2021 Jan-Dec;35:20587384211036819
International journal of immunopathology and pharmacology 2021 Jan-Dec;35:20587384211036819
Valproic acid Suppresses Breast Cancer Cell Growth Through Triggering Pyruvate Kinase M2 Isoform Mediated Warburg Effect.
Li Z, Yang L, Zhang S, Song J, Sun H, Shan C, Wang D, Liu S
Cell transplantation 2021 Jan-Dec;30:9636897211027524
Cell transplantation 2021 Jan-Dec;30:9636897211027524
Electroacupuncture Attenuates Morphine Tolerance in Rats with Bone Cancer Pain by Inhibiting PI3K/Akt/JNK1/2 Signaling Pathway in the Spinal Dorsal Horn.
Jiang B, Zhong X, Fang J, Zhang A, WangD W, Liang Y, Fang J, Chen F, Du J
Integrative cancer therapies 2021 Jan-Dec;20:1534735421995237
Integrative cancer therapies 2021 Jan-Dec;20:1534735421995237
Thermoresponsive GenisteinNLC-dexamethasone-moxifloxacin multi drug delivery system in lens capsule bag to prevent complications after cataract surgery.
Yan T, Ma Z, Liu J, Yin N, Lei S, Zhang X, Li X, Zhang Y, Kong J
Scientific reports 2021 Jan 8;11(1):181
Scientific reports 2021 Jan 8;11(1):181
Antioxidant and Immunomodulatory Properties of Partially purified Exopolysaccharide from Lactobacillus Casei Isolated from Chinese Northeast Sauerkraut.
Xu X, Qiao Y, Peng Q, Shi B, Dia VP
Immunological investigations 2021 Jan 8;:1-18
Immunological investigations 2021 Jan 8;:1-18
Effects of ER-resident and secreted AGR2 on cell proliferation, migration, invasion, and survival in PANC-1 pancreatic cancer cells.
Hong X, Li ZX, Hou J, Zhang HY, Zhang CY, Zhang J, Sun H, Pang LH, Wang T, Deng ZH
BMC cancer 2021 Jan 7;21(1):33
BMC cancer 2021 Jan 7;21(1):33
Intraperitoneal injection of Desferal® alleviated the age-related bone loss and senescence of bone marrow stromal cells in rats.
Yi L, Ju Y, He Y, Yin X, Xu Y, Weng T
Stem cell research & therapy 2021 Jan 7;12(1):45
Stem cell research & therapy 2021 Jan 7;12(1):45
Indoleamine 2,3-dioxygenase 1 limits hepatic inflammatory cells recruitment and promotes bile duct ligation-induced liver fibrosis.
Mo C, Xie S, Liu B, Zhong W, Zeng T, Huang S, Lai Y, Deng G, Zhou C, Yan W, Chen Y, Huang S, Gao L, Lv Z
Cell death & disease 2021 Jan 7;12(1):16
Cell death & disease 2021 Jan 7;12(1):16
Rabies virus matrix protein targets host actin cytoskeleton: a protein-protein interaction analysis.
Zandi F, Khalaj V, Goshadrou F, Meyfour A, Gholami A, Enayati S, Mehranfar M, Rahmati S, Kheiri EV, Badie HG, Vaziri B
Pathogens and disease 2021 Jan 6;79(1)
Pathogens and disease 2021 Jan 6;79(1)
Lnc-GAN1 expression is associated with good survival and suppresses tumor progression by sponging mir-26a-5p to activate PTEN signaling in non-small cell lung cancer.
Wang RQ, Long XR, Zhou NN, Chen DN, Zhang MY, Wen ZS, Zhang LJ, He FZ, Zhou ZL, Mai SJ, Wang HY
Journal of experimental & clinical cancer research : CR 2021 Jan 6;40(1):9
Journal of experimental & clinical cancer research : CR 2021 Jan 6;40(1):9
MCCC2 promotes HCC development by supporting leucine oncogenic function.
Chen YY, Zhang XN, Xu CZ, Zhou DH, Chen J, Liu ZX, Sun Y, Huang W, Qu LS
Cancer cell international 2021 Jan 6;21(1):22
Cancer cell international 2021 Jan 6;21(1):22
Environmental noise stress disturbs commensal microbiota homeostasis and induces oxi-inflammmation and AD-like neuropathology through epithelial barrier disruption in the EOAD mouse model.
Chi H, Cao W, Zhang M, Su D, Yang H, Li Z, Li C, She X, Wang K, Gao X, Ma K, Zheng P, Li X, Cui B
Journal of neuroinflammation 2021 Jan 6;18(1):9
Journal of neuroinflammation 2021 Jan 6;18(1):9
miR-142 downregulation alleviates rat PTSD-like behaviors, reduces the level of inflammatory cytokine expression and apoptosis in hippocampus, and upregulates the expression of fragile X mental retardation protein.
Nie PY, Tong L, Li MD, Fu CH, Peng JB, Ji LL
Journal of neuroinflammation 2021 Jan 6;18(1):17
Journal of neuroinflammation 2021 Jan 6;18(1):17
Leptin Receptor (LEPR) promotes proliferation, migration, and invasion and inhibits apoptosis in hepatocellular carcinoma by regulating ANXA7.
Huang H, Zhang J, Ling F, Huang Y, Yang M, Zhang Y, Wei Y, Zhang Q, Wang H, Song L, Wu Y, Yang J, Tang J
Cancer cell international 2021 Jan 4;21(1):4
Cancer cell international 2021 Jan 4;21(1):4
Tumor genotype dictates radiosensitization after Atm deletion in primary brainstem glioma models.
Deland K, Starr BF, Mercer JS, Byemerwa J, Crabtree DM, Williams NT, Luo L, Ma Y, Chen M, Becher OJ, Kirsch DG
The Journal of clinical investigation 2021 Jan 4;131(1)
The Journal of clinical investigation 2021 Jan 4;131(1)
Improvement of obesity-associated disorders by a small-molecule drug targeting mitochondria of adipose tissue macrophages.
Wang Y, Tang B, Long L, Luo P, Xiang W, Li X, Wang H, Jiang Q, Tan X, Luo S, Li H, Wang Z, Chen Z, Leng Y, Jiang Z, Wang Y, Ma L, Wang R, Zeng C, Liu Z, Wang Y, Miao H, Shi C
Nature communications 2021 Jan 4;12(1):102
Nature communications 2021 Jan 4;12(1):102
Interplay of opposing fate choices stalls oncogenic growth in murine skin epithelium.
Sandoval M, Ying Z, Beronja S
eLife 2021 Jan 4;10
eLife 2021 Jan 4;10
Neuroprotective effects of SOX5 against ischemic stroke by regulating VEGF/PI3K/AKT pathway.
Zhang W, Wu Y, Chen H, Yu D, Zhao J, Chen J
Gene 2021 Jan 30;767:145148
Gene 2021 Jan 30;767:145148
Discovery and proteomics analysis of effective compounds in Valeriana jatamansi jones for the treatment of anxiety.
Wang SN, Yao ZW, Zhao CB, Ding YS, Jing-Luo, Bian LH, Li QY, Wang XM, Shi JL, Guo JY, Wang CG
Journal of ethnopharmacology 2021 Jan 30;265:113452
Journal of ethnopharmacology 2021 Jan 30;265:113452
Angiogenesis is promoted by exosomal DPP4 derived from 5-fluorouracil-resistant colon cancer cells.
Zheng X, Liu J, Li X, Tian R, Shang K, Dong X, Cao B
Cancer letters 2021 Jan 28;497:190-201
Cancer letters 2021 Jan 28;497:190-201
LncRNA H19-Derived miR-675-5p Accelerates the Invasion of Extravillous Trophoblast Cells by Inhibiting GATA2 and Subsequently Activating Matrix Metalloproteinases.
Ogoyama M, Ohkuchi A, Takahashi H, Zhao D, Matsubara S, Takizawa T
International journal of molecular sciences 2021 Jan 27;22(3)
International journal of molecular sciences 2021 Jan 27;22(3)
Connective tissue growth factor promotes chemotaxis of preosteoblasts through integrin α5 and Ras during tensile force-induced intramembranous osteogenesis.
Jiang W, Takeshita N, Maeda T, Sogi C, Oyanagi T, Kimura S, Yoshida M, Sasaki K, Ito A, Takano-Yamamoto T
Scientific reports 2021 Jan 27;11(1):2368
Scientific reports 2021 Jan 27;11(1):2368
Echinatin effectively protects against NLRP3 inflammasome-driven diseases by targeting HSP90.
Xu G, Fu S, Zhan X, Wang Z, Zhang P, Shi W, Qin N, Chen Y, Wang C, Niu M, Guo Y, Wang J, Bai Z, Xiao X
JCI insight 2021 Jan 25;6(2)
JCI insight 2021 Jan 25;6(2)
Vitamin D alleviates liver fibrosis by inhibiting histidine-rich calcium binding protein (HRC).
Lu W, Li X, Liu N, Zhang Y, Li Y, Pan Y, Yang J, Liu Z, Kong J
Chemico-biological interactions 2021 Jan 25;334:109355
Chemico-biological interactions 2021 Jan 25;334:109355
Immunophenotype of Gastric Tumors Unveils a Pleiotropic Role of Regulatory T Cells in Tumor Development.
Rocha S, Basto AP, Ijsselsteijn ME, Teles SP, Azevedo MM, Gonçalves G, Gullo I, Almeida GM, Maqueda JJ, Oliveira MI, Carneiro F, Barata JT, Graça L, de Miranda NFCC, Carvalho J, Oliveira C
Cancers 2021 Jan 23;13(3)
Cancers 2021 Jan 23;13(3)
Long-read transcriptome sequencing reveals abundant promoter diversity in distinct molecular subtypes of gastric cancer.
Huang KK, Huang J, Wu JKL, Lee M, Tay ST, Kumar V, Ramnarayanan K, Padmanabhan N, Xu C, Tan ALK, Chan C, Kappei D, Göke J, Tan P
Genome biology 2021 Jan 22;22(1):44
Genome biology 2021 Jan 22;22(1):44
A novel oncotherapy strategy: Direct thrombin inhibitors suppress progression, dissemination and spontaneous metastasis in non-small cell lung cancer.
Zhao B, Wu M, Hu Z, Wang T, Yu J, Ma Y, Wang Q, Zhang Y, Chen D, Li T, Li Y, Yu M, Wang H, Mo W
British journal of pharmacology 2021 Jan 22;
British journal of pharmacology 2021 Jan 22;
Discovery of a Functional Covalent Ligand Targeting an Intrinsically Disordered Cysteine within MYC.
Boike L, Cioffi AG, Majewski FC, Co J, Henning NJ, Jones MD, Liu G, McKenna JM, Tallarico JA, Schirle M, Nomura DK
Cell chemical biology 2021 Jan 21;28(1):4-13.e17
Cell chemical biology 2021 Jan 21;28(1):4-13.e17
Human umbilical cord mesenchymal stem cell-derived exosomal miR-146a-5p reduces microglial-mediated neuroinflammation via suppression of the IRAK1/TRAF6 signaling pathway after ischemic stroke.
Zhang Z, Zou X, Zhang R, Xie Y, Feng Z, Li F, Han J, Sun H, Ouyang Q, Hua S, Lv B, Hua T, Liu Z, Cai Y, Zou Y, Tang Y, Jiang X
Aging 2021 Jan 21;13(2):3060-3079
Aging 2021 Jan 21;13(2):3060-3079
SERCA2a ameliorates cardiomyocyte T-tubule remodeling via the calpain/JPH2 pathway to improve cardiac function in myocardial ischemia/reperfusion mice.
Wang S, Zhou Y, Luo Y, Kan R, Chen J, Xuan H, Wang C, Chen J, Xu T, Li D
Scientific reports 2021 Jan 21;11(1):2037
Scientific reports 2021 Jan 21;11(1):2037
Identification of Cleavage Sites Proteolytically Processed by NS2B-NS3 Protease in Polyprotein of Japanese Encephalitis Virus.
Wahaab A, Liu K, Hameed M, Anwar MN, Kang L, Li C, Ma X, Wajid A, Yang Y, Khan UH, Wei J, Li B, Shao D, Qiu Y, Ma Z
Pathogens (Basel, Switzerland) 2021 Jan 21;10(2)
Pathogens (Basel, Switzerland) 2021 Jan 21;10(2)
An Autism-Associated Mutation Impairs Neuroligin-4 Glycosylation and Enhances Excitatory Synaptic Transmission in Human Neurons.
Cast TP, Boesch DJ, Smyth K, Shaw AE, Ghebrial M, Chanda S
The Journal of neuroscience : the official journal of the Society for Neuroscience 2021 Jan 20;41(3):392-407
The Journal of neuroscience : the official journal of the Society for Neuroscience 2021 Jan 20;41(3):392-407
Notoginsenoside R1 attenuates breast cancer progression by targeting CCND2 and YBX3.
Qin HL, Wang XJ, Yang BX, Du B, Yun XL
Chinese medical journal 2021 Jan 20;134(5):546-554
Chinese medical journal 2021 Jan 20;134(5):546-554
Adipose-derived stromal cells improve functional recovery after spinal cord injury through TGF-β1/Smad3/PLOD2 pathway activation.
Li F, Liu H, Zhang K, Xiao DJ, Wang C, Wang YS
Aging 2021 Jan 20;13(3):4370-4387
Aging 2021 Jan 20;13(3):4370-4387
The mitochondrial protein ERAL1 suppresses RNA virus infection by facilitating RIG-I-like receptor signaling.
Li S, Kuang M, Chen L, Li Y, Liu S, Du H, Cao L, You F
Cell reports 2021 Jan 19;34(3):108631
Cell reports 2021 Jan 19;34(3):108631
Development of DNA Vaccine Targeting E6 and E7 Proteins of Human Papillomavirus 16 (HPV16) and HPV18 for Immunotherapy in Combination with Recombinant Vaccinia Boost and PD-1 Antibody.
Peng S, Ferrall L, Gaillard S, Wang C, Chi WY, Huang CH, Roden RBS, Wu TC, Chang YN, Hung CF
mBio 2021 Jan 19;12(1)
mBio 2021 Jan 19;12(1)
Hsa_circ_0007456 regulates the natural killer cell-mediated cytotoxicity toward hepatocellular carcinoma via the miR-6852-3p/ICAM-1 axis.
Shi M, Li ZY, Zhang LM, Wu XY, Xiang SH, Wang YG, Zhang YQ
Cell death & disease 2021 Jan 18;12(1):94
Cell death & disease 2021 Jan 18;12(1):94
Human RECQL5 promotes metastasis and resistance to cisplatin in non-small cell lung cancer.
Xia HW, Zhang ZQ, Yuan J, Niu QL
Life sciences 2021 Jan 15;265:118768
Life sciences 2021 Jan 15;265:118768
MicroRNA-150 affects endoplasmic reticulum stress via MALAT1-miR-150 axis-mediated NF-κB pathway in LPS-challenged HUVECs and septic mice.
Liu L, Yan LN, Sui Z
Life sciences 2021 Jan 15;265:118744
Life sciences 2021 Jan 15;265:118744
Discovery of a novel small-molecule inhibitor of Fam20C that induces apoptosis and inhibits migration in triple negative breast cancer.
Zhao R, Fu L, Yuan Z, Liu Y, Zhang K, Chen Y, Wang L, Sun D, Chen L, Liu B, Zhang L
European journal of medicinal chemistry 2021 Jan 15;210:113088
European journal of medicinal chemistry 2021 Jan 15;210:113088
Atractylodis macrocephalae polysaccharides protect against DSS-induced intestinal injury through a novel lncRNA ITSN1-OT1.
Zong X, Xiao X, Kai L, Cheng Y, Fu J, Xu W, Wang Y, Zhao K, Jin M
International journal of biological macromolecules 2021 Jan 15;167:76-84
International journal of biological macromolecules 2021 Jan 15;167:76-84
Circ_0001438 participates in the pathogenesis of preeclampsia via the circ_0001438/miR-942/NLRP3 regulatory network.
Li X, Yang R, Xu Y, Zhang Y
Placenta 2021 Jan 15;104:40-50
Placenta 2021 Jan 15;104:40-50
Single cell transcriptomic analysis of human pluripotent stem cell chondrogenesis.
Wu CL, Dicks A, Steward N, Tang R, Katz DB, Choi YR, Guilak F
Nature communications 2021 Jan 13;12(1):362
Nature communications 2021 Jan 13;12(1):362
Functional constipation induces bladder overactivity associated with upregulations of Htr2 and Trpv2 pathways.
Iguchi N, Carrasco A Jr, Xie AX, Pineda RH, Malykhina AP, Wilcox DT
Scientific reports 2021 Jan 13;11(1):1149
Scientific reports 2021 Jan 13;11(1):1149
Genome-wide Screens Identify Lineage- and Tumor-Specific Genes Modulating MHC-I- and MHC-II-Restricted Immunosurveillance of Human Lymphomas.
Dersh D, Phelan JD, Gumina ME, Wang B, Arbuckle JH, Holly J, Kishton RJ, Markowitz TE, Seedhom MO, Fridlyand N, Wright GW, Huang DW, Ceribelli M, Thomas CJ, Lack JB, Restifo NP, Kristie TM, Staudt LM, Yewdell JW
Immunity 2021 Jan 12;54(1):116-131.e10
Immunity 2021 Jan 12;54(1):116-131.e10
miR-199b-5p enhances the proliferation of medullary thymic epithelial cells via regulating Wnt signaling by targeting Fzd6.
Wang X, Li Y, Gong B, Zhang K, Ma Y, Li Y
Acta biochimica et biophysica Sinica 2021 Jan 12;53(1):36-45
Acta biochimica et biophysica Sinica 2021 Jan 12;53(1):36-45
The DDX39B/FUT3/TGFβR-I axis promotes tumor metastasis and EMT in colorectal cancer.
He C, Li A, Lai Q, Ding J, Yan Q, Liu S, Li Q
Cell death & disease 2021 Jan 12;12(1):74
Cell death & disease 2021 Jan 12;12(1):74
Cellular and molecular landscape of mammalian sinoatrial node revealed by single-cell RNA sequencing.
Liang D, Xue J, Geng L, Zhou L, Lv B, Zeng Q, Xiong K, Zhou H, Xie D, Zhang F, Liu J, Liu Y, Li L, Yang J, Xue Z, Chen YH
Nature communications 2021 Jan 12;12(1):287
Nature communications 2021 Jan 12;12(1):287
Transcription elongation factor A-like 7, regulated by miR-758-3p inhibits the progression of melanoma through decreasing the expression levels of c-Myc and AKT1.
Liu X, Song X, Li H
Cancer cell international 2021 Jan 11;21(1):43
Cancer cell international 2021 Jan 11;21(1):43
Mtu1 defects are correlated with reduced osteogenic differentiation.
He Q, Zhao Q, Li Q, Pan R, Li X, Chen Y
Cell death & disease 2021 Jan 11;12(1):61
Cell death & disease 2021 Jan 11;12(1):61
Knockdown of CENPF inhibits the progression of lung adenocarcinoma mediated by ERβ2/5 pathway.
Hexiao T, Yuquan B, Lecai X, Yanhong W, Li S, Weidong H, Ming X, Xuefeng Z, Gaofeng P, Li Z, Minglin Z, Zheng T, Zetian Y, Xiao Z, Yi C, Lanuti M, Jinping Z
Aging 2021 Jan 10;13(2):2604-2625
Aging 2021 Jan 10;13(2):2604-2625
Tetrachlorobenzoquinone exhibits immunotoxicity by inducing neutrophil extracellular traps through a mechanism involving ROS-JNK-NOX2 positive feedback loop.
Lv X, Liu Z, Xu L, Song E, Song Y
Environmental pollution (Barking, Essex : 1987) 2021 Jan 1;268(Pt B):115921
Environmental pollution (Barking, Essex : 1987) 2021 Jan 1;268(Pt B):115921
Canstatin represses glioma growth by inhibiting formation of VM-like structures.
Ma Y, Wu T, Zhou H, He G, Li Y, Wang B, Guo Q, Chen B, Li W
Translational neuroscience 2021 Jan 1;12(1):309-319
Translational neuroscience 2021 Jan 1;12(1):309-319
SQSTM1/ p62 oligomerization contributes to Aβ-induced inhibition of Nrf2 signaling.
Guo C, Zhang Y, Nie Q, Cao D, Wang X, Wan X, Liu M, Cui J, Sun J, Bai Y, Li L
Neurobiology of aging 2021 Feb;98:10-20
Neurobiology of aging 2021 Feb;98:10-20
Kiaa0101 serves as a prognostic marker and promotes invasion by regulating p38/snail1 pathway in glioma.
Liu J, Gao L, Liao J, Yang J, Yuan F, Chen Q
Annals of translational medicine 2021 Feb;9(3):260
Annals of translational medicine 2021 Feb;9(3):260
Eldecalcitol induces apoptosis and autophagy in human osteosarcoma MG-63 cells by accumulating ROS to suppress the PI3K/Akt/mTOR signaling pathway.
Zhang C, Huang C, Yang P, Li C, Li M
Cellular signalling 2021 Feb;78:109841
Cellular signalling 2021 Feb;78:109841
Gastrin-17 induces gastric cancer cell epithelial-mesenchymal transition via the Wnt/β-catenin signaling pathway.
Li Y, Zhao Y, Li Y, Zhang X, Li C, Long N, Chen X, Bao L, Zhou J, Xie Y
Journal of physiology and biochemistry 2021 Feb;77(1):93-104
Journal of physiology and biochemistry 2021 Feb;77(1):93-104
RNA-binding protein HuR suppresses senescence through Atg7 mediated autophagy activation in diabetic intervertebral disc degeneration.
Shao Z, Ni L, Hu S, Xu T, Meftah Z, Yu Z, Tian N, Wu Y, Sun L, Wu A, Pan Z, Chen L, Gao W, Zhou Y, Zhang X, Wang X
Cell proliferation 2021 Feb;54(2):e12975
Cell proliferation 2021 Feb;54(2):e12975
Kcnh2 mediates FAK/AKT-FOXO3A pathway to attenuate sepsis-induced cardiac dysfunction.
Li Z, Meng Y, Liu C, Liu H, Cao W, Tong C, Lu M, Li L, Peng L
Cell proliferation 2021 Feb;54(2):e12962
Cell proliferation 2021 Feb;54(2):e12962
lncRNA NEAT1 ameliorates LPS‑induced inflammation in MG63 cells by activating autophagy and suppressing the NLRP3 inflammasome.
Dai W, Wang M, Wang P, Wen J, Wang J, Cha S, Xiao X, He Y, Shu R, Bai D
International journal of molecular medicine 2021 Feb;47(2):607-620
International journal of molecular medicine 2021 Feb;47(2):607-620
lncRNA FOXP4‑AS1 predicts poor prognosis and accelerates the progression of mantle cell lymphoma through the miR‑423‑5p/NACC1 pathway.
Tao HF, Shen JX, Hou ZW, Chen SY, Su YZ, Fang JL
Oncology reports 2021 Feb;45(2):469-480
Oncology reports 2021 Feb;45(2):469-480
Circular RNA circNFATC3 acts as a miR-9-5p sponge to promote cervical cancer development by upregulating SDC2.
Ma N, Li X, Wei H, Zhang H, Zhang S
Cellular oncology (Dordrecht) 2021 Feb;44(1):93-107
Cellular oncology (Dordrecht) 2021 Feb;44(1):93-107
OPA1 haploinsufficiency due to a novel splicing variant resulting in mitochondrial dysfunction without mitochondrial DNA depletion.
Sun C, Wu X, Bai HX, Wang C, Liu Z, Yang C, Lu Y, Jiang P
Ophthalmic genetics 2021 Feb;42(1):45-52
Ophthalmic genetics 2021 Feb;42(1):45-52
CRISPR/Cas9 screening identifies a kinetochore-microtubule dependent mechanism for Aurora-A inhibitor resistance in breast cancer.
Chen A, Wen S, Liu F, Zhang Z, Liu M, Wu Y, He B, Yan M, Kang T, Lam EW, Wang Z, Liu Q
Cancer communications (London, England) 2021 Feb;41(2):121-139
Cancer communications (London, England) 2021 Feb;41(2):121-139
PRMT1 enhances oncogenic arginine methylation of NONO in colorectal cancer.
Yin XK, Wang YL, Wang F, Feng WX, Bai SM, Zhao WW, Feng LL, Wei MB, Qin CL, Wang F, Chen ZL, Yi HJ, Huang Y, Xie PY, Kim T, Wang YN, Hou JW, Li CW, Liu Q, Fan XJ, Hung MC, Wan XB
Oncogene 2021 Feb;40(7):1375-1389
Oncogene 2021 Feb;40(7):1375-1389
miR-23a-3p regulated by LncRNA SNHG5 suppresses the chondrogenic differentiation of human adipose-derived stem cells via targeting SOX6/SOX5.
Yang Z, Ren Z, She R, Ao J, Wa Q, Sun Z, Li B, Tian X
Cell and tissue research 2021 Feb;383(2):723-733
Cell and tissue research 2021 Feb;383(2):723-733
MicroRNA-936/ERBB4/Akt axis exhibits anticancer properties of gastric cancer through inhibition of cell proliferation, migration, and invasion.
Liu S, Gong Y, Xu XD, Shen H, Gao S, Bao HD, Guo SB, Yu XF, Gong J
The Kaohsiung journal of medical sciences 2021 Feb;37(2):111-120
The Kaohsiung journal of medical sciences 2021 Feb;37(2):111-120
The Kv1.3 ion channel acts as a host factor restricting viral entry.
Lang Y, Li F, Liu Q, Xia Z, Ji Z, Hu J, Cheng Y, Gao M, Sun F, Shen B, Xie C, Yi W, Wu Y, Yao J, Cao Z
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 Feb;35(2):e20995
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 Feb;35(2):e20995
Rosmarinic acid exerts an antagonistic effect on nonalcoholic fatty liver disease by regulating the YAP1/TAZ-PPARγ/PGC-1α signaling pathway.
Luo C, Sun H, Peng J, Gao C, Bao L, Ji R, Zhang C, Zhu W, Jin Y
Phytotherapy research : PTR 2021 Feb;35(2):1010-1022
Phytotherapy research : PTR 2021 Feb;35(2):1010-1022
COPII mitigates ER stress by promoting formation of ER whorls.
Xu F, Du W, Zou Q, Wang Y, Zhang X, Xing X, Li Y, Zhang D, Wang H, Zhang W, Hu X, Liu X, Liu X, Zhang S, Yu J, Fang J, Li F, Zhou Y, Yue T, Mi N, Deng H, Zou P, Chen X, Yang X, Yu L
Cell research 2021 Feb;31(2):141-156
Cell research 2021 Feb;31(2):141-156
UBE2O targets Mxi1 for ubiquitination and degradation to promote lung cancer progression and radioresistance.
Huang Y, Yang X, Lu Y, Zhao Y, Meng R, Zhang S, Dong X, Xu S, Wu G
Cell death and differentiation 2021 Feb;28(2):671-684
Cell death and differentiation 2021 Feb;28(2):671-684
TDP-43 aggregation induced by oxidative stress causes global mitochondrial imbalance in ALS.
Zuo X, Zhou J, Li Y, Wu K, Chen Z, Luo Z, Zhang X, Liang Y, Esteban MA, Zhou Y, Fu XD
Nature structural & molecular biology 2021 Feb;28(2):132-142
Nature structural & molecular biology 2021 Feb;28(2):132-142
The interaction between lipocalin 2 and dipyridine ketone hydrazone dithiocarbamte may influence respective function in proliferation and metastasis-related gene expressions in HepG2 cell.
Li C, Li Y, Lou L, Han X, Wang H, Huang T, Li C
Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 2021 Feb;26(1):123-133
Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 2021 Feb;26(1):123-133
M2 macrophage-derived G-CSF promotes trophoblasts EMT, invasion and migration via activating PI3K/Akt/Erk1/2 pathway to mediate normal pregnancy.
Ding J, Yang C, Zhang Y, Wang J, Zhang S, Guo D, Yin T, Yang J
Journal of cellular and molecular medicine 2021 Feb;25(4):2136-2147
Journal of cellular and molecular medicine 2021 Feb;25(4):2136-2147
LINC01116 promotes proliferation and migration of endometrial stromal cells by targeting FOXP1 via sponging miR-9-5p in endometriosis.
Cui L, Chen S, Wang D, Yang Q
Journal of cellular and molecular medicine 2021 Feb;25(4):2000-2012
Journal of cellular and molecular medicine 2021 Feb;25(4):2000-2012
FoxM1 promotes Wnt/β-catenin pathway activation and renal fibrosis via transcriptionally regulating multi-Wnts expressions.
Xie H, Miao N, Xu D, Zhou Z, Ni J, Yin F, Wang Y, Cheng Q, Chen P, Li J, Zheng P, Zhou L, Liu J, Zhang W, Wang X, Lu L
Journal of cellular and molecular medicine 2021 Feb;25(4):1958-1971
Journal of cellular and molecular medicine 2021 Feb;25(4):1958-1971
AGGF1 inhibits the expression of inflammatory mediators and promotes angiogenesis in dental pulp cells.
Shen S, Shang L, Liu H, Liang Q, Liang W, Ge S
Clinical oral investigations 2021 Feb;25(2):581-592
Clinical oral investigations 2021 Feb;25(2):581-592
Ptk2b deletion improves mice folliculogenesis and fecundity via inhibiting follicle loss mediated by Erk pathway.
Cong Y, Wu H, Bian X, Xie Q, Lyu Q, Cui J, Suo L, Kuang Y
Journal of cellular physiology 2021 Feb;236(2):1043-1053
Journal of cellular physiology 2021 Feb;236(2):1043-1053
Molecular mechanism underlying miR‑130b‑Sp1 transcriptional regulation in LPS‑induced upregulation of MUC5AC in the bile duct epithelium.
Wu X, Yao C, Kong J, Tian Y, Fan Y, Zhang Z, Han J, Wu S
Molecular medicine reports 2021 Feb;23(2)
Molecular medicine reports 2021 Feb;23(2)
Knockdown of long non‑coding RNA ANRIL inhibits the proliferation and promotes the apoptosis of Burkitt lymphoma cells through the TGF‑β1 signaling pathway.
Mao S, Jin J, Li Z, Yang W
Molecular medicine reports 2021 Feb;23(2)
Molecular medicine reports 2021 Feb;23(2)
Matrix metalloproteinase 3 regulates angiotensin II‑induced myocardial fibrosis cell viability, migration and apoptosis.
Shu J, Gu Y, Jin L, Wang H
Molecular medicine reports 2021 Feb;23(2)
Molecular medicine reports 2021 Feb;23(2)
Benzidine promotes the stemness of bladder cancer stem cells via activation of the Sonic hedgehog pathway.
Wang D, Xie D, Bi L, Wang Y, Zou C, Chen L, Geng H, Qian W, Li Y, Sun H, Wang X, Lu Y, Yu D, Zhong C
Oncology letters 2021 Feb;21(2):146
Oncology letters 2021 Feb;21(2):146
Crosstalk between phosphorylation and ubiquitination is involved in high salt-induced WNK4 expression.
Zhao X, Lai G, Tu J, Liu S, Zhao Y
Experimental and therapeutic medicine 2021 Feb;21(2):133
Experimental and therapeutic medicine 2021 Feb;21(2):133
Dysregulation of phosphoproteins in hepatocellular carcinoma revealed via quantitative analysis of the phosphoproteome.
Liu Y, Zhao Q, Xu F, Wang K, Zhao Y, Chen H, He W, Wang W, Zhang J, Zhang J
Oncology letters 2021 Feb;21(2):117
Oncology letters 2021 Feb;21(2):117
Inhibition of autophagy aggravates molybdenum-induced mitochondrial dysfunction by aggravating oxidative stress in duck renal tubular epithelial cells.
Zhuang J, Nie G, Hu R, Wang C, Xing C, Li G, Hu G, Yang F, Zhang C
Ecotoxicology and environmental safety 2021 Feb;209:111771
Ecotoxicology and environmental safety 2021 Feb;209:111771
Clinical and molecular characterization of thirty Chinese patients with congenital lipoid adrenal hyperplasia.
Zhang T, Ma X, Wang J, Jia C, Wang W, Dong Z, Ye L, Sun S, Hu R, Ning G, Li C, Lu W
The Journal of steroid biochemistry and molecular biology 2021 Feb;206:105788
The Journal of steroid biochemistry and molecular biology 2021 Feb;206:105788
Viral RNA-binding ability conferred by SUMOylation at PB1 K612 of influenza A virus is essential for viral pathogenesis and transmission.
Li J, Liang L, Jiang L, Wang Q, Wen X, Zhao Y, Cui P, Zhang Y, Wang G, Li Q, Deng G, Shi J, Tian G, Zeng X, Jiang Y, Liu L, Chen H, Li C
PLoS pathogens 2021 Feb;17(2):e1009336
PLoS pathogens 2021 Feb;17(2):e1009336
Predicting therapeutic drugs for hepatocellular carcinoma based on tissue-specific pathways.
Yu L, Wang M, Yang Y, Xu F, Zhang X, Xie F, Gao L, Li X
PLoS computational biology 2021 Feb;17(2):e1008696
PLoS computational biology 2021 Feb;17(2):e1008696
Cryptotanshinone specifically suppresses NLRP3 inflammasome activation and protects against inflammasome-mediated diseases.
Liu H, Zhan X, Xu G, Wang Z, Li R, Wang Y, Qin Q, Shi W, Hou X, Yang R, Wang J, Xiao X, Bai Z
Pharmacological research 2021 Feb;164:105384
Pharmacological research 2021 Feb;164:105384
Genistein inhibits radiation-induced invasion and migration of glioblastoma cells by blocking the DNA-PKcs/Akt2/Rac1 signaling pathway.
Liu X, Wang Q, Liu B, Zheng X, Li P, Zhao T, Jin X, Ye F, Zhang P, Chen W, Li Q
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 2021 Feb;155:93-104
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 2021 Feb;155:93-104
20-HETE downregulates Na/K-ATPase α1 expression via the ubiquitination pathway.
Zhang B, Xu R, Fang G, Zhao Y
Prostaglandins & other lipid mediators 2021 Feb;152:106503
Prostaglandins & other lipid mediators 2021 Feb;152:106503
Loss of STAT5A promotes glucose metabolism and tumor growth through miRNA-23a-AKT signaling in hepatocellular carcinoma.
Jiang Y, Tao Y, Zhang X, Wei X, Li M, He X, Zhou B, Guo W, Yin H, Cheng S
Molecular oncology 2021 Feb;15(2):710-724
Molecular oncology 2021 Feb;15(2):710-724
Compound heterozygous mutation of the ASXL3 gene causes autosomal recessive congenital heart disease.
Fu F, Li R, Lei TY, Wang D, Yang X, Han J, Pan M, Zhen L, Li J, Li FT, Jing XY, Li DZ, Liao C
Human genetics 2021 Feb;140(2):333-348
Human genetics 2021 Feb;140(2):333-348
Whole-Transcriptome Profiling of Human Heart Tissues Reveals the Potential Novel Players and Regulatory Networks in Different Cardiomyopathy Subtypes of Heart Failure.
Liu CF, Ni Y, Moravec CS, Morley M, Ashley EA, Cappola TP, Margulies KB, Tang WHW
Circulation. Genomic and precision medicine 2021 Feb;14(1):e003142
Circulation. Genomic and precision medicine 2021 Feb;14(1):e003142
Knockdown of dual oxidase 1 suppresses activin A-induced fibrosis in cardiomyocytes via the reactive oxygen species-dependent pyroptotic pathway.
Li S, Li Z, Yin R, Nie J, Fu Y, Ying R
The international journal of biochemistry & cell biology 2021 Feb;131:105902
The international journal of biochemistry & cell biology 2021 Feb;131:105902
MicroRNA-520c-3p targeting of RelA/p65 suppresses atherosclerotic plaque formation.
Wang J, Hu X, Hu X, Gao F, Li M, Cui Y, Wei X, Qin Y, Zhang C, Zhao Y, Gao Y
The international journal of biochemistry & cell biology 2021 Feb;131:105873
The international journal of biochemistry & cell biology 2021 Feb;131:105873
MiR-146a mediates TLR-4 signaling pathway to affect myocardial fibrosis in rat constrictive pericarditis model.
Xiao Y, Qiao W, Wang X, Sun L, Ren W
Journal of thoracic disease 2021 Feb;13(2):935-945
Journal of thoracic disease 2021 Feb;13(2):935-945
RabGEF1 functions as an oncogene in U251 glioblastoma cells and is involved in regulating AKT and Erk pathways.
Fan H, Xin T, Dong X, Yang F, Zhang R, Feng S, He D, Guo H, Pang Q
Experimental and molecular pathology 2021 Feb;118:104571
Experimental and molecular pathology 2021 Feb;118:104571
A loss-of-function mutation p.T256M in NDRG4 is implicated in the pathogenesis of pulmonary atresia with ventricular septal defect (PA/VSD) and tetralogy of Fallot (TOF).
Peng J, Wang Q, Meng Z, Wang J, Zhou Y, Zhou S, Song W, Chen S, Chen AF, Sun K
FEBS open bio 2021 Feb;11(2):375-385
FEBS open bio 2021 Feb;11(2):375-385
Layer-by-layer self-assembly polyelectrolytes loaded with cyclic adenosine monophosphate enhances the osteo/odontogenic differentiation of stem cells from apical papilla.
Zhang J, Zhao IS, Yu OY, Li Q, Mei ML, Zhang C, Chu CH
Journal of biomedical materials research. Part A 2021 Feb;109(2):207-218
Journal of biomedical materials research. Part A 2021 Feb;109(2):207-218
HOXA10 mediates epithelial-mesenchymal transition to promote gastric cancer metastasis partly via modulation of TGFB2/Smad/METTL3 signaling axis.
Song C, Zhou C
Journal of experimental & clinical cancer research : CR 2021 Feb 9;40(1):62
Journal of experimental & clinical cancer research : CR 2021 Feb 9;40(1):62
FKBP10 promotes proliferation of glioma cells via activating AKT-CREB-PCNA axis.
Cai HQ, Zhang MJ, Cheng ZJ, Yu J, Yuan Q, Zhang J, Cai Y, Yang LY, Zhang Y, Hao JJ, Wang MR, Wan JH
Journal of biomedical science 2021 Feb 9;28(1):13
Journal of biomedical science 2021 Feb 9;28(1):13
DDB2 regulates DNA replication through PCNA-independent degradation of CDT2.
Wu X, Yu M, Zhang Z, Leng F, Ma Y, Xie N, Lu F
Cell & bioscience 2021 Feb 8;11(1):34
Cell & bioscience 2021 Feb 8;11(1):34
miR-374 improves cerebral ischemia reperfusion injury by targeting Wnt5a.
Xing F, Liu Y, Dong R, Cheng Y
Experimental animals 2021 Feb 6;70(1):126-136
Experimental animals 2021 Feb 6;70(1):126-136
Adipocyte-specific deletion of zinc finger protein 407 results in lipodystrophy and insulin resistance in mice.
Charrier A, Xu X, Guan BJ, Ngo J, Wynshaw-Boris A, Hatzoglou M, Buchner DA
Molecular and cellular endocrinology 2021 Feb 5;521:111109
Molecular and cellular endocrinology 2021 Feb 5;521:111109
Humanin regulates oxidative stress in the ovaries of polycystic ovary syndrome patients via the Keap1/Nrf2 pathway.
Wang Y, Li N, Zeng Z, Tang L, Zhao S, Zhou F, Zhou L, Xia W, Zhu C, Rao M
Molecular human reproduction 2021 Feb 5;27(2)
Molecular human reproduction 2021 Feb 5;27(2)
RTN1-C mediates cerebral ischemia/reperfusion injury via modulating autophagy.
Ling J, Cai H, Lin M, Qi S, Du J, Chen L
Acta biochimica et biophysica Sinica 2021 Feb 4;53(2):170-178
Acta biochimica et biophysica Sinica 2021 Feb 4;53(2):170-178
Long non-coding RNA CCDC183-AS1 acts AS a miR-589-5p sponge to promote the progression of hepatocellular carcinoma through regulating SKP1 expression.
Zhu H, Zhang H, Pei Y, Liao Z, Liu F, Su C, Liu Y, Dong R, Song J, Zhang X, Fan Y, Liang H, Zhang B, Chen X
Journal of experimental & clinical cancer research : CR 2021 Feb 4;40(1):57
Journal of experimental & clinical cancer research : CR 2021 Feb 4;40(1):57
miR-224-5p Contained in Urinary Extracellular Vesicles Regulates PD-L1 Expression by Inhibiting Cyclin D1 in Renal Cell Carcinoma Cells.
Qin Z, Hu H, Sun W, Chen L, Jin S, Xu Q, Liu Y, Yu L, Zeng S
Cancers 2021 Feb 4;13(4)
Cancers 2021 Feb 4;13(4)
Angiopoietin 2 stimulates trophoblast invasion via a mechanism associated with JNK signaling.
Hou H, Ning F, Zhang JY, Lu Q, Zhang M, Wu P, Chen M, Lash GE
Molecular human reproduction 2021 Feb 27;27(3)
Molecular human reproduction 2021 Feb 27;27(3)
Prpf31 is essential for the survival and differentiation of retinal progenitor cells by modulating alternative splicing.
Li J, Liu F, Lv Y, Sun K, Zhao Y, Reilly J, Zhang Y, Tu J, Yu S, Liu X, Qin Y, Huang Y, Gao P, Jia D, Chen X, Han Y, Shu X, Luo D, Tang Z, Liu M
Nucleic acids research 2021 Feb 26;49(4):2027-2043
Nucleic acids research 2021 Feb 26;49(4):2027-2043
Cancer-associated fibroblast-derived SDF-1 induces epithelial-mesenchymal transition of lung adenocarcinoma via CXCR4/β-catenin/PPARδ signalling.
Wang Y, Lan W, Xu M, Song J, Mao J, Li C, Du X, Jiang Y, Li E, Zhang R, Wang Q
Cell death & disease 2021 Feb 26;12(2):214
Cell death & disease 2021 Feb 26;12(2):214
UBE3C promotes proliferation and inhibits apoptosis by activating the β-catenin signaling via degradation of AXIN1 in gastric cancer.
Zhang Y, Xu J, Fu H, Wei Z, Yang D, Yan R
Carcinogenesis 2021 Feb 25;42(2):285-293
Carcinogenesis 2021 Feb 25;42(2):285-293
Inhibition of the Otub1/c-Maf axis by the herbal acevaltrate induces myeloma cell apoptosis.
Sun T, Xu Y, Xu Z, Cao B, Zhang Z, Wang Q, Kong Y, Mao X
Cell communication and signaling : CCS 2021 Feb 24;19(1):24
Cell communication and signaling : CCS 2021 Feb 24;19(1):24
Radiotherapy and immunotherapy converge on elimination of tumor-promoting erythroid progenitor cells through adaptive immunity.
Hou Y, Liang HL, Yu X, Liu Z, Cao X, Rao E, Huang X, Wang L, Li L, Bugno J, Fu Y, Chmura SJ, Wu W, Luo SZ, Zheng W, Arina A, Jutzy J, McCall AR, Vokes EE, Pitroda SP, Fu YX, Weichselbaum RR
Science translational medicine 2021 Feb 24;13(582)
Science translational medicine 2021 Feb 24;13(582)
p53 induces ARTS to promote mitochondrial apoptosis.
Hao Q, Chen J, Liao J, Huang Y, Gan Y, Larisch S, Zeng SX, Lu H, Zhou X
Cell death & disease 2021 Feb 24;12(2):204
Cell death & disease 2021 Feb 24;12(2):204
Pterostilbene inhibits gallbladder cancer progression by suppressing the PI3K/Akt pathway.
Tong C, Wang Y, Li J, Cen W, Zhang W, Zhu Z, Yu J, Lu B
Scientific reports 2021 Feb 23;11(1):4391
Scientific reports 2021 Feb 23;11(1):4391
Genome-wide analysis of pseudogenes reveals HBBP1's human-specific essentiality in erythropoiesis and implication in β-thalassemia.
Ma Y, Liu S, Gao J, Chen C, Zhang X, Yuan H, Chen Z, Yin X, Sun C, Mao Y, Zhou F, Shao Y, Liu Q, Xu J, Cheng L, Yu D, Li P, Yi P, He J, Geng G, Guo Q, Si Y, Zhao H, Li H, Banes GL, Liu H, Nakamura Y, Kurita R, Huang Y, Wang X, Wang F, Fang G, Engel JD, Shi L, Zhang YE, Yu J
Developmental cell 2021 Feb 22;56(4):478-493.e11
Developmental cell 2021 Feb 22;56(4):478-493.e11
Abnormal level of paxillin in cervical cancer cells is involved in tumor progression and invasion.
Gu H, Wen J
Acta biochimica Polonica 2021 Feb 20;68(1):49-53
Acta biochimica Polonica 2021 Feb 20;68(1):49-53
Glycogen synthase kinase 3 beta inhibitor SB216763 improves Kir2.1 expression after myocardia infraction in rats.
Chang C, Wang SH, Xu LN, Su XL, Zeng YF, Wang P, Zhang LR, Han SN
Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing 2021 Feb 20;
Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing 2021 Feb 20;
Nuclear factor Y participates in alcoholic liver disease by activating SREBP1 expression in mice.
Zhang Y, Sun Y, Zhang Y, Miao Q, Wang Q, Yang B, Li Y, Li L, Zhang R
Biochemical and biophysical research communications 2021 Feb 19;541:90-94
Biochemical and biophysical research communications 2021 Feb 19;541:90-94
SFPQ regulates the accumulation of RNA foci and dipeptide repeat proteins from the expanded repeat mutation in C9orf72.
Malnar M, Rogelj B
Journal of cell science 2021 Feb 19;134(4)
Journal of cell science 2021 Feb 19;134(4)
GBP5 drives malignancy of glioblastoma via the Src/ERK1/2/MMP3 pathway.
Yu X, Jin J, Zheng Y, Zhu H, Xu H, Ma J, Lan Q, Zhuang Z, Chen CC, Li M
Cell death & disease 2021 Feb 19;12(2):203
Cell death & disease 2021 Feb 19;12(2):203
LncRNA CDKN2B-AS1 stabilized by IGF2BP3 drives the malignancy of renal clear cell carcinoma through epigenetically activating NUF2 transcription.
Xie X, Lin J, Fan X, Zhong Y, Chen Y, Liu K, Ren Y, Chen X, Lai D, Li X, Li Z, Tang A
Cell death & disease 2021 Feb 19;12(2):201
Cell death & disease 2021 Feb 19;12(2):201
E3 ligase Nedd4l promotes antiviral innate immunity by catalyzing K29-linked cysteine ubiquitination of TRAF3.
Gao P, Ma X, Yuan M, Yi Y, Liu G, Wen M, Jiang W, Ji R, Zhu L, Tang Z, Yu Q, Xu J, Yang R, Xia S, Yang M, Pan J, Yuan H, An H
Nature communications 2021 Feb 19;12(1):1194
Nature communications 2021 Feb 19;12(1):1194
LncRNA HOXA-AS3 promotes gastric cancer progression by regulating miR-29a-3p/LTβR and activating NF-κB signaling.
Qu F, Zhu B, Hu YL, Mao QS, Feng Y
Cancer cell international 2021 Feb 18;21(1):118
Cancer cell international 2021 Feb 18;21(1):118
Critical roles of sphingosine kinase 1 in the regulation of neuroinflammation and neuronal injury after spinal cord injury.
Wang C, Xu T, Lachance BB, Zhong X, Shen G, Xu T, Tang C, Jia X
Journal of neuroinflammation 2021 Feb 18;18(1):50
Journal of neuroinflammation 2021 Feb 18;18(1):50
Direct activation of endothelial cells by SARS-CoV-2 nucleocapsid protein is blocked by Simvastatin.
Qian Y, Lei T, Patel PS, Lee CH, Monaghan-Nichols P, Xin HB, Qiu J, Fu M
bioRxiv : the preprint server for biology 2021 Feb 18;
bioRxiv : the preprint server for biology 2021 Feb 18;
Hepatic connective tissue growth factor expression and regulation differ between non-steatotic and non-alcoholic steatotic livers from brain-dead donor.
Yang DJ, Shi JH, Xia ZP, Guo WZ, Ahmed MS, Zhang SJ
Scientific reports 2021 Feb 16;11(1):3857
Scientific reports 2021 Feb 16;11(1):3857
CREB1 protects against the renal injury in a rat model of kidney stone disease and calcium oxalate monohydrate crystals-induced injury in NRK-52E cells.
Yu L, Gan X, Bai Y, An R
Toxicology and applied pharmacology 2021 Feb 15;413:115394
Toxicology and applied pharmacology 2021 Feb 15;413:115394
Down-regulation of A3AR signaling by IL-6-induced GRK2 activation contributes to Th17 cell differentiation.
Hu S, Guo P, Wang Z, Zhou Z, Wang R, Zhang M, Tao J, Tai Y, Zhou W, Wei W, Wang Q
Experimental cell research 2021 Feb 15;399(2):112482
Experimental cell research 2021 Feb 15;399(2):112482
Nobiletin downregulates the SKP2-p21/p27-CDK2 axis to inhibit tumor progression and shows synergistic effects with palbociclib on renal cell carcinoma.
Chen T, Liu L, Zou Y, Hu X, Zhang W, Zhou T, Luo X, Fu W, Xu J
Cancer biology & medicine 2021 Feb 15;18(1):227-244
Cancer biology & medicine 2021 Feb 15;18(1):227-244
RECQL4 regulates DNA damage response and redox homeostasis in esophageal cancer.
Lyu G, Su P, Hao X, Chen S, Ren S, Zhao Z, Gong Y, Liu Q, Shao C
Cancer biology & medicine 2021 Feb 15;18(1):120-138
Cancer biology & medicine 2021 Feb 15;18(1):120-138
Gentisic acid prevents diet-induced obesity in mice by accelerating the thermogenesis of brown adipose tissue.
Han X, Guo J, Gao Y, Zhan J, You Y, Huang W
Food & function 2021 Feb 15;12(3):1262-1270
Food & function 2021 Feb 15;12(3):1262-1270
Uric acid inhibits HMGB1-TLR4-NF-κB signaling to alleviate oxygen-glucose deprivation/reoxygenation injury of microglia.
Wang Q, Zhao H, Gao Y, Lu J, Xie, Yu W, He F, Liu W, Hisatome I, Yamamoto T, Wang W, Cheng J
Biochemical and biophysical research communications 2021 Feb 12;540:22-28
Biochemical and biophysical research communications 2021 Feb 12;540:22-28
A novel regulatory loop miR-101/ANXA2/EGR1 mediates malignant characteristics of liver cancer stem cells.
Ma S, Cheng J, Wang H, Ding N, Zhou F, Ji R, Zhu L, Zhu C, Pan Y
Carcinogenesis 2021 Feb 11;42(1):93-104
Carcinogenesis 2021 Feb 11;42(1):93-104
DUOX2 promotes the progression of colorectal cancer cells by regulating the AKT pathway and interacting with RPL3.
Zhang X, Han J, Feng L, Zhi L, Jiang D, Yu B, Zhang Z, Gao B, Zhang C, Li M, Zhao L, Wang G
Carcinogenesis 2021 Feb 11;42(1):105-117
Carcinogenesis 2021 Feb 11;42(1):105-117
Icariside I specifically facilitates ATP or nigericin-induced NLRP3 inflammasome activation and causes idiosyncratic hepatotoxicity.
Gao Y, Xu G, Ma L, Shi W, Wang Z, Zhan X, Qin N, He T, Guo Y, Niu M, Wang J, Bai Z, Xiao X
Cell communication and signaling : CCS 2021 Feb 11;19(1):13
Cell communication and signaling : CCS 2021 Feb 11;19(1):13
The DNA methylation-regulated MCTP1 activates the drug-resistance of esophageal cancer cells.
Kong L, Yang W, Chen L, Qian L
Aging 2021 Feb 11;13(3):3342-3352
Aging 2021 Feb 11;13(3):3342-3352
Formononetin attenuates atopic dermatitis by upregulating A20 expression via activation of G protein-coupled estrogen receptor.
Yuan W, Chen Y, Zhou Y, Bao K, Yu X, Xu Y, Zhang Y, Zheng J, Jiang G, Hong M
Journal of ethnopharmacology 2021 Feb 10;266:113397
Journal of ethnopharmacology 2021 Feb 10;266:113397
Gas6 or Mer deficiency ameliorates silica-induced autophagosomes accumulation in mice lung.
Li W, Xie L, Ma J, Cheng M, Fan L, Xu Y, Wang B, Chen W
Toxicology letters 2021 Feb 1;337:28-37
Toxicology letters 2021 Feb 1;337:28-37
Berberine regulates macrophage polarization through IL-4-STAT6 signaling pathway in Helicobacter pylori-induced chronic atrophic gastritis.
Yang T, Wang R, Liu H, Wang L, Li J, Wu S, Chen X, Yang X, Zhao Y
Life sciences 2021 Feb 1;266:118903
Life sciences 2021 Feb 1;266:118903
The PDZ Domain Protein SYNJ2BP Regulates GRK-Dependent Sst2A Phosphorylation and Downstream MAPK Signaling.
Carr HS, Chang JT, Frost JA
Endocrinology 2021 Feb 1;162(2)
Endocrinology 2021 Feb 1;162(2)
ATM inhibition enhances cancer immunotherapy by promoting mtDNA leakage and cGAS/STING activation.
Hu M, Zhou M, Bao X, Pan D, Jiao M, Liu X, Li F, Li CY
The Journal of clinical investigation 2021 Feb 1;131(3)
The Journal of clinical investigation 2021 Feb 1;131(3)
The S1PR1 agonist SEW2871 promotes the survival of skin flap.
Zhang D, Qi D, Xu Y, Hu C, Zhang X, Yang Q, Shang Z, Zhang G
Canadian journal of physiology and pharmacology 2021 Dec;99(12):1280-1287
Canadian journal of physiology and pharmacology 2021 Dec;99(12):1280-1287
Red ginseng has stronger anti-aging effects compared to ginseng possibly due to its regulation of oxidative stress and the gut microbiota.
Peng X, Hao M, Zhao Y, Cai Y, Chen X, Chen H, Zhang Y, Dong L, Liu X, Ding C, Liu W, Yang M, Luo Y
Phytomedicine : international journal of phytotherapy and phytopharmacology 2021 Dec;93:153772
Phytomedicine : international journal of phytotherapy and phytopharmacology 2021 Dec;93:153772
LncRNA CAIF suppresses LPS-induced inflammation and apoptosis of cardiomyocytes through regulating miR-16 demethylation.
Wang Y, Zhang Y
Immunity, inflammation and disease 2021 Dec;9(4):1468-1478
Immunity, inflammation and disease 2021 Dec;9(4):1468-1478
Mechanism of neutrophil extracellular traps generation and their role in trophoblasts apoptosis in gestational diabetes mellitus.
Shen D, Lu Y, Li G, Hu M, Li S, Ju H, Zhang M, Wang X
Cellular signalling 2021 Dec;88:110168
Cellular signalling 2021 Dec;88:110168
Ginsenoside Rb1 alleviates liver injury induced by 3-chloro-1,2-propanediol by stimulating autophagic flux.
Lu J, Lu J, Bu X, Li Y, Ge G, Guan S
Journal of food science 2021 Dec;86(12):5503-5515
Journal of food science 2021 Dec;86(12):5503-5515
Maternal Benzophenone Exposure Impairs Hippocampus Development and Cognitive Function in Mouse Offspring.
Cui F, Pan Q, Wang S, Zhao F, Wang R, Zhang T, Song Y, He J, Zhang H, Weng Q, Jin Y, Xia W, Li Y, Yang GY, De Vos WH, Timmermans JP, Xu S, Tang Y, Sheng X
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2021 Dec;8(23):e2102686
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2021 Dec;8(23):e2102686
Targeting conserved N-glycosylation blocks SARS-CoV-2 variant infection in vitro.
Huang HC, Lai YJ, Liao CC, Yang WF, Huang KB, Lee IJ, Chou WC, Wang SH, Wang LH, Hsu JM, Sun CP, Kuo CT, Wang J, Hsiao TC, Yang PJ, Lee TA, Huang W, Li FA, Shen CY, Lin YL, Tao MH, Li CW
EBioMedicine 2021 Dec;74:103712
EBioMedicine 2021 Dec;74:103712
MiR-192-5p suppresses M1 macrophage polarization via epiregulin (EREG) downregulation in gouty arthritis.
An L, Yin F
Tissue & cell 2021 Dec;73:101669
Tissue & cell 2021 Dec;73:101669
Molecular Mechanism of the ATF6α/S1P/S2P Signaling Pathway in Hippocampal Neuronal Apoptosis in SPS Rats.
Han L, Xu Y, Shi Y
Journal of molecular neuroscience : MN 2021 Dec;71(12):2487-2499
Journal of molecular neuroscience : MN 2021 Dec;71(12):2487-2499
Trametinib enhances ATRA-induced differentiation in AML cells.
Lu H, Li ZY, Ding M, Liang C, Weng XQ, Sheng Y, Wu J, Cai X
Leukemia & lymphoma 2021 Dec;62(14):3361-3372
Leukemia & lymphoma 2021 Dec;62(14):3361-3372
Increased expression of PSME2 is associated with clear cell renal cell carcinoma invasion by regulating BNIP3‑mediated autophagy.
Wang X, Wu F, Deng Y, Chai J, Zhang Y, He G, Li X
International journal of oncology 2021 Dec;59(6)
International journal of oncology 2021 Dec;59(6)
Wei Chang An pill regulates gastrointestinal motility in a bidirectional manner.
Jia S, Chai L, Zhang J, Zhang M, Li L, Qi Y, Pang Y, Chen X, Fan N, Wang L, Wang Y, Song J, Sun Y, Wang Y, Miao L, Zhang H
Pharmaceutical biology 2021 Dec;59(1):1452-1463
Pharmaceutical biology 2021 Dec;59(1):1452-1463
CoCrMo-Nanoparticles induced peri-implant osteolysis by promoting osteoblast ferroptosis via regulating Nrf2-ARE signalling pathway.
Xu Y, Sang W, Zhong Y, Xue S, Yang M, Wang C, Lu H, Huan R, Mao X, Zhu L, He C, Ma J
Cell proliferation 2021 Dec;54(12):e13142
Cell proliferation 2021 Dec;54(12):e13142
Bone marrow macrophage-derived exosomal miR-143-5p contributes to insulin resistance in hepatocytes by repressing MKP5.
Li L, Zuo H, Huang X, Shen T, Tang W, Zhang X, An T, Dou L, Li J
Cell proliferation 2021 Dec;54(12):e13140
Cell proliferation 2021 Dec;54(12):e13140
Splicing factor proline and glutamine rich intron retention, reduced expression and aggregate formation are pathological features of amyotrophic lateral sclerosis.
Hogan AL, Grima N, Fifita JA, McCann EP, Heng B, Fat SCM, Wu S, Maharjan R, Cain AK, Henden L, Rayner S, Tarr I, Zhang KY, Zhao Q, Zhang ZH, Wright A, Lee A, Morsch M, Yang S, Williams KL, Blair IP
Neuropathology and applied neurobiology 2021 Dec;47(7):990-1003
Neuropathology and applied neurobiology 2021 Dec;47(7):990-1003
Role of miR-145-5p/ CD40 in the inflammation and apoptosis of HUVECs induced by PM2.5.
Zhang X, Qi W, Shi Y, Li X, Yin J, Huo C, Zhang R, Zhao W, Ye J, Zhou L, Ye L
Toxicology 2021 Dec;464:152993
Toxicology 2021 Dec;464:152993
Endoplasmic reticulum stress pathway mediates T-2 toxin-induced chondrocyte apoptosis.
Liu YN, Mu YD, Wang H, Zhang M, Shi YW, Mi G, Peng LX, Chen JH
Toxicology 2021 Dec;464:152989
Toxicology 2021 Dec;464:152989
YTHDF1 promotes the proliferation, migration, and invasion of prostate cancer cells by regulating TRIM44.
Li W, Chen G, Feng Z, Zhu B, Zhou L, Zhang Y, Mai J, Jiang C, Zeng J
Genes & genomics 2021 Dec;43(12):1413-1421
Genes & genomics 2021 Dec;43(12):1413-1421
Activation of SK3 channel plays a pivotal role in modulation of trigeminal neuralgia.
Zhao J, Zhang Y, Liu X, Rao Y, Fu J, Hua L, Ou C
Neurological research 2021 Dec;43(12):1005-1012
Neurological research 2021 Dec;43(12):1005-1012
Endothelial METTL3 (Methyltransferase-Like 3) Inhibits Fibrinolysis by Promoting PAI-1 (Plasminogen Activator Inhibitor-1) Expression Through Enhancing Jun Proto-Oncogene N6-Methyladenosine Modification.
Bai Q, Lu Y, Chen Y, Zhang H, Zhang W, Wu H, Wen A
Arteriosclerosis, thrombosis, and vascular biology 2021 Dec;41(12):2877-2889
Arteriosclerosis, thrombosis, and vascular biology 2021 Dec;41(12):2877-2889
Exposure interval to ambient fine particulate matter (PM2.5) collected in Southwest China induced pulmonary damage through the Janus tyrosine protein kinase-2/signal transducer and activator of transcription-3 signaling pathway both in vivo and in vitro.
Yue W, Chen X, He S, Li N, Zhang L, Chen J
Journal of applied toxicology : JAT 2021 Dec;41(12):2042-2054
Journal of applied toxicology : JAT 2021 Dec;41(12):2042-2054
Lobetyolin inhibits the proliferation of breast cancer cells via ASCT2 down-regulation-induced apoptosis.
Chen Y, Tian Y, Jin G, Cui Z, Guo W, Zhang X, Liu X
Human & experimental toxicology 2021 Dec;40(12):2074-2086
Human & experimental toxicology 2021 Dec;40(12):2074-2086
Insulin-like growth factor reduced against decabromodiphenyl ether-209-induced neurodevelopmental toxicity in vivo and in vitro.
Yang Y, He Q, Zhang Z, Qi C, Ding L, Yuan T, Chen Y, Li Z
Human & experimental toxicology 2021 Dec;40(12_suppl):S475-S486
Human & experimental toxicology 2021 Dec;40(12_suppl):S475-S486
Non-canonical activation of the ER stress sensor ATF6 by Legionella pneumophila effectors.
Ibe NU, Subramanian A, Mukherjee S
Life science alliance 2021 Dec;4(12)
Life science alliance 2021 Dec;4(12)
Expression of CD47 in the pancreatic β-cells of people with recent-onset type 1 diabetes varies according to disease endotype.
Leslie KA, Richardson SJ, Russell MA, Morgan NG
Diabetic medicine : a journal of the British Diabetic Association 2021 Dec;38(12):e14724
Diabetic medicine : a journal of the British Diabetic Association 2021 Dec;38(12):e14724
Two Inhibitors Against the 3C-Like Proteases of Swine Coronavirus and Feline Coronavirus.
Zhou M, Han Y, Li M, Ye G, Peng G
Virologica Sinica 2021 Dec;36(6):1421-1430
Virologica Sinica 2021 Dec;36(6):1421-1430
Angiomotin-like 1 plays a tumor-promoting role in glioma by enhancing the activation of YAP1 signaling.
Xu G, Seng Z, Zhang M, Qu J
Environmental toxicology 2021 Dec;36(12):2500-2511
Environmental toxicology 2021 Dec;36(12):2500-2511
Amelioratory effect of neoandrographolide on myocardial ischemic-reperfusion injury by its anti-inflammatory and anti-apoptotic activities.
Liu Y, Liu Y, Zhang HL, Yu FF, Yin XR, Zhao YF, Ye F, Wu XQ
Environmental toxicology 2021 Dec;36(12):2367-2379
Environmental toxicology 2021 Dec;36(12):2367-2379
Dual inhibition of EGFR and IL-6-STAT3 signalling by miR-146b: a potential targeted therapy for epithelial ovarian cancer.
Yan M, Han M, Yang X, Shen R, Wang H, Zhang L, Xia S, Yang P, Zhai G, Shao Q
Journal of enzyme inhibition and medicinal chemistry 2021 Dec;36(1):1905-1915
Journal of enzyme inhibition and medicinal chemistry 2021 Dec;36(1):1905-1915
CircPrkcsh, a circular RNA, contributes to the polarization of microglia towards the M1 phenotype induced by spinal cord injury and acts via the JNK/p38 MAPK pathway.
Li X, Kang J, Lv H, Liu R, Chen J, Zhang Y, Zhang Y, Yu G, Zhang X, Ning B
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 Dec;35(12):e22014
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 Dec;35(12):e22014
BAIAP2L2 promotes the proliferation, migration and invasion of osteosarcoma associated with the Wnt/β-catenin pathway.
Guo H, Peng J, Hu J, Chang S, Liu H, Luo H, Chen X, Tang H, Chen Y
Journal of bone oncology 2021 Dec;31:100393
Journal of bone oncology 2021 Dec;31:100393
Mdivi-1 alleviates atopic dermatitis through the inhibition of NLRP3 inflammasome.
Li L, Mu Z, Liu P, Wang Y, Yang F, Han X
Experimental dermatology 2021 Dec;30(12):1734-1744
Experimental dermatology 2021 Dec;30(12):1734-1744
Mitophagy mediates metabolic reprogramming of induced pluripotent stem cells undergoing endothelial differentiation.
Krantz S, Kim YM, Srivastava S, Leasure JW, Toth PT, Marsboom G, Rehman J
The Journal of biological chemistry 2021 Dec;297(6):101410
The Journal of biological chemistry 2021 Dec;297(6):101410
Blockade of JAK2 signaling produces immunomodulatory effect to preserve pancreatic homeostasis in severe acute pancreatitis.
Qiu Z, Xu F, Wang Z, Yang P, Bu Z, Cheng F, Jiang H, Li L, Zhang F
Biochemistry and biophysics reports 2021 Dec;28:101133
Biochemistry and biophysics reports 2021 Dec;28:101133
Protective effect of Idelalisib on carbon tetrachloride-induced liver fibrosis via microRNA-124-3P/phosphatidylinositol-3-hydroxykinase signalling pathway.
Li X, Li H, Zhang S, Zhang R, Li J, Wei Y, Yang C, Zhang F, Zhou H
Journal of cellular and molecular medicine 2021 Dec;25(24):11185-11197
Journal of cellular and molecular medicine 2021 Dec;25(24):11185-11197
MET inhibition enhances PARP inhibitor efficacy in castration-resistant prostate cancer by suppressing the ATM/ATR and PI3K/AKT pathways.
Zhou S, Dai Z, Wang L, Gao X, Yang L, Wang Z, Wang Q, Liu Z
Journal of cellular and molecular medicine 2021 Dec;25(24):11157-11169
Journal of cellular and molecular medicine 2021 Dec;25(24):11157-11169
Depletion of m6 A reader protein YTHDC1 induces dilated cardiomyopathy by abnormal splicing of Titin.
Gao S, Sun H, Chen K, Gu X, Chen H, Jiang L, Chen L, Zhang S, Liu Y, Shi D, Liang D, Xu L, Yang J, Ruan Y, Chen H, Shen B, Ma H, Chen YH
Journal of cellular and molecular medicine 2021 Dec;25(23):10879-10891
Journal of cellular and molecular medicine 2021 Dec;25(23):10879-10891
hsa‑miR‑429 targets CBX8 to promote cell apoptosis in diffuse large B‑cell lymphoma.
Liang Y, Yu ZJ, Liu M, Liu HM, Zhang JZ, Xiong T, Tang YY, Huang ZP
Molecular medicine reports 2021 Dec;24(6)
Molecular medicine reports 2021 Dec;24(6)
Peroxisome proliferator‑activated receptor β/δ regulates cerebral vasospasm after subarachnoid hemorrhage via modulating vascular smooth muscle cells phenotypic conversion.
Xu L, Wu J, Liu Y, Chen G, Ma C, Zhang H
Molecular medicine reports 2021 Dec;24(6)
Molecular medicine reports 2021 Dec;24(6)
MicroRNA-602 prevents the development of inflammatory bowel diseases in a microbiota-dependent manner.
Zhao S, Zhu L, Feng W, Zhang L, Chen DD, Hu YC, Shen H
Experimental and therapeutic medicine 2021 Dec;22(6):1373
Experimental and therapeutic medicine 2021 Dec;22(6):1373
Diterpenoid alkaloids from Delphinium forrestii var. viride and their anti-inflammation activity.
Song Z, Gao C, Jiang Q, Xu J, Xiong L, Liu K, Sun D, Li H, Chen L
Phytochemistry 2021 Dec;192:112971
Phytochemistry 2021 Dec;192:112971
MicroRNA-455-5p/CPEB1 pathway mediates Aβ-related learning and memory deficits in a mouse model of Alzheimer's disease.
Xiao G, Chen Q, Zhang X
Brain research bulletin 2021 Dec;177:282-294
Brain research bulletin 2021 Dec;177:282-294
Resveratrol and its derivative pterostilbene attenuate oxidative stress-induced intestinal injury by improving mitochondrial redox homeostasis and function via SIRT1 signaling.
Chen Y, Zhang H, Ji S, Jia P, Chen Y, Li Y, Wang T
Free radical biology & medicine 2021 Dec;177:1-14
Free radical biology & medicine 2021 Dec;177:1-14
Isosteroidal alkaloids from Fritillaria hupehensis Hsiao et K.C.Hsia: Synthesis and biological evaluation of alkaloid derivatives as potential cytotoxic agents.
Liu XH, Zou J, Li YJ, Liu M, He CL, Liu YR, Wang JZ, Chen DL
Steroids 2021 Dec;176:108929
Steroids 2021 Dec;176:108929
CUL3 (cullin 3)-mediated ubiquitination and degradation of BECN1 (beclin 1) inhibit autophagy and promote tumor progression.
Li X, Yang KB, Chen W, Mai J, Wu XQ, Sun T, Wu RY, Jiao L, Li DD, Ji J, Zhang HL, Yu Y, Chen YH, Feng GK, Deng R, Li JD, Zhu XF
Autophagy 2021 Dec;17(12):4323-4340
Autophagy 2021 Dec;17(12):4323-4340
Ferritinophagy is involved in the zinc oxide nanoparticles-induced ferroptosis of vascular endothelial cells.
Qin X, Zhang J, Wang B, Xu G, Yang X, Zou Z, Yu C
Autophagy 2021 Dec;17(12):4266-4285
Autophagy 2021 Dec;17(12):4266-4285
Long noncoding RNA (lncRNA) EIF3J-DT induces chemoresistance of gastric cancer via autophagy activation.
Luo Y, Zheng S, Wu Q, Wu J, Zhou R, Wang C, Wu Z, Rong X, Huang N, Sun L, Bin J, Liao Y, Shi M, Liao W
Autophagy 2021 Dec;17(12):4083-4101
Autophagy 2021 Dec;17(12):4083-4101
Lanthanum chloride induces autophagy in primary cultured rat cortical neurons through Akt/mTOR and AMPK/mTOR signaling pathways.
Gao X, Yu M, Sun W, Han Y, Yang J, Lu X, Jin C, Wu S, Cai Y
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2021 Dec;158:112632
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2021 Dec;158:112632
Pentagalloylglucose reduces AGE-induced inflammation by activating Nrf2/HO-1 and inhibiting the JAK2/STAT3 pathway in mesangial cells.
Tong J, Fang J, Zhu T, Xiang P, Shang J, Chen L, Zhao J, Wang Y, Tong L, Sun M
Journal of pharmacological sciences 2021 Dec;147(4):305-314
Journal of pharmacological sciences 2021 Dec;147(4):305-314
Pyruvate kinase M2 (PKM2) interacts with activating transcription factor 2 (ATF2) to bridge glycolysis and pyroptosis in microglia.
Li M, Lu H, Wang X, Duan C, Zhu X, Zhang Y, Ge X, Ji F, Wang X, Su J, Zhang D
Molecular immunology 2021 Dec;140:250-266
Molecular immunology 2021 Dec;140:250-266
LncRNA RP1-86C11.7 exacerbates the glioma progression and oncogenicity by hsa-miR-144-3p/TFRC signaling.
Ma Q, Wang X, Li J
Translational oncology 2021 Dec;14(12):101215
Translational oncology 2021 Dec;14(12):101215
Ablation of USP21 in skeletal muscle promotes oxidative fibre phenotype, inhibiting obesity and type 2 diabetes.
Kim A, Koo JH, Jin X, Kim W, Park SY, Park S, Rhee EP, Choi CS, Kim SG
Journal of cachexia, sarcopenia and muscle 2021 Dec;12(6):1669-1689
Journal of cachexia, sarcopenia and muscle 2021 Dec;12(6):1669-1689
Linc00467 promotion of gastric cancer development by directly regulating miR-7-5p expression and downstream epidermal growth factor receptor.
Deng LH, Zhao H, Bai LP, Xie J, Liu K, Yan F
Bioengineered 2021 Dec;12(2):9484-9495
Bioengineered 2021 Dec;12(2):9484-9495
Hsa_circ_0030586 promotes epithelial-mesenchymal transition in prostate cancer via PI3K-AKT signaling.
Luo GC, Chen L, Fang J, Yan ZJ
Bioengineered 2021 Dec;12(2):11089-11107
Bioengineered 2021 Dec;12(2):11089-11107
Ubiquitin-associated protein 2 like (UBAP2L) enhances growth and metastasis of gastric cancer cells.
Lin S, Yan Z, Tang Q, Zhang S
Bioengineered 2021 Dec;12(2):10232-10245
Bioengineered 2021 Dec;12(2):10232-10245
Orosomucoid 1 promotes epirubicin resistance in breast cancer by upregulating the expression of matrix metalloproteinases 2 and 9.
Qiong L, Yin J
Bioengineered 2021 Dec;12(1):8822-8832
Bioengineered 2021 Dec;12(1):8822-8832
Solid lipid nanoparticle delivery of rhynchophylline enhanced the efficiency of allergic asthma treatment via the upregulation of suppressor of cytokine signaling 1 by repressing the p38 signaling pathway.
Lv C, Li H, Cui H, Bi Q, Wang M
Bioengineered 2021 Dec;12(1):8635-8649
Bioengineered 2021 Dec;12(1):8635-8649
MiR-1224-5p attenuates polycystic ovary syndrome through inhibiting NOD-like receptor protein 3 inflammasome activation via targeting Forkhead box O 1.
Li Y, Yao N, Gao Y, Wang Y, Bai L, Xu J, Wang H
Bioengineered 2021 Dec;12(1):8555-8569
Bioengineered 2021 Dec;12(1):8555-8569
Long non-coding RNA LOC107985656 represses the proliferation of hepatocellular carcinoma cells through activation of the tumor-suppressive Hippo pathway.
Zeng Y, Xu Q, Xu N
Bioengineered 2021 Dec;12(1):7964-7974
Bioengineered 2021 Dec;12(1):7964-7974
Impact of hepatocyte-specific deletion of staphylococcal nuclease and tudor domain containing 1 (SND1) on liver insulin resistance and acute liver failure of mice.
Zhao C, Cui X, Zhao Y, Qian B, Zhang N, Xin L, Ha C, Yang J, Wang X, Gao X
Bioengineered 2021 Dec;12(1):7360-7375
Bioengineered 2021 Dec;12(1):7360-7375
Dynamic Dissection of Dynein and Kinesin-1 Cooperatively Mediated Intercellular Transport of Porcine Epidemic Diarrhea Coronavirus along Microtubule Using Single Virus Tracking.
Hou W, Kang W, Li Y, Shan Y, Wang S, Liu F
Virulence 2021 Dec;12(1):615-629
Virulence 2021 Dec;12(1):615-629
Site-specific SUMOylation of viral polymerase processivity factor: a way of localizingtoND10 subnuclear domains for restricted and self-controlled reproduction of herpesvirus.
Lai S, Xu M, Wang Y, Li R, Xia C, Xia S, Chen J
Virulence 2021 Dec;12(1):2883-2901
Virulence 2021 Dec;12(1):2883-2901
Long non-coding RNA (lncRNA) PGM5P4-AS1 inhibits lung cancer progression by up-regulating leucine zipper tumor suppressor (LZTS3) through sponging microRNA miR-1275.
Feng J, Li J, Qie P, Li Z, Xu Y, Tian Z
Bioengineered 2021 Dec;12(1):196-207
Bioengineered 2021 Dec;12(1):196-207
Catalpol ameliorates psoriasis-like phenotypes via SIRT1 mediated suppression of NF-κB and MAPKs signaling pathways.
Liu A, Zhang B, Zhao W, Tu Y, Wang Q, Li J
Bioengineered 2021 Dec;12(1):183-195
Bioengineered 2021 Dec;12(1):183-195
A novel circular RNA (hsa_circ_0059930)-mediated miRNA-mRNA axis in the lipopolysaccharide-induced acute lung injury model of MRC-5 cells.
Han J, Li S, Feng Y, He Y, Hong W, Ye Z
Bioengineered 2021 Dec;12(1):1739-1751
Bioengineered 2021 Dec;12(1):1739-1751
Long intergenic noncoding RNA00265 promotes proliferation of gastric cancer via the microRNA-144-3p/Chromobox 4 axis.
Yang Z, OuYang X, Zheng L, Dai L, Luo W
Bioengineered 2021 Dec;12(1):1012-1025
Bioengineered 2021 Dec;12(1):1012-1025
Tyrosine kinase nonreceptor 1 (TNK1) knockdown ameliorates hemorrhage shock-induced kidney injury via inhibiting macrophage M1 polarization.
Tang M, Cai J, Wang Y, Huan Z, Yao H, Xu C, Ge X, Song S
3 Biotech 2021 Dec;11(12):501
3 Biotech 2021 Dec;11(12):501
Spatiotemporal regulation of JAZ4 expression and splicing contribute to ethylene- and auxin-mediated responses in Arabidopsis roots.
DeMott L, Oblessuc PR, Pierce A, Student J, Melotto M
The Plant journal : for cell and molecular biology 2021 Dec;108(5):1266-1282
The Plant journal : for cell and molecular biology 2021 Dec;108(5):1266-1282
Veratric acid alleviates liver ischemia/reperfusion injury by activating the Nrf2 signaling pathway.
Yu Q, Chen S, Tang H, Zhang X, Tao R, Yan Z, Shi J, Guo W, Zhang S
International immunopharmacology 2021 Dec;101(Pt B):108294
International immunopharmacology 2021 Dec;101(Pt B):108294
The impact of tobacco exposure on tumor microenvironment and prognosis in lung adenocarcinoma by integrative analysis of multi-omics data.
Lu X, Ma L, Yin X, Ji H, Qian Y, Zhong S, Yan A, Zhang Y
International immunopharmacology 2021 Dec;101(Pt B):108253
International immunopharmacology 2021 Dec;101(Pt B):108253
Sulfiredoxin-1 protects retinal ganglion cells from high glucose-induced oxidative stress and inflammatory injury by potentiating Nrf2 signaling via the Akt/GSK-3β pathway.
Zhu F, Shao J, Tian Y, Xu Z
International immunopharmacology 2021 Dec;101(Pt B):108221
International immunopharmacology 2021 Dec;101(Pt B):108221
Topoisomerase 2 inhibitor etoposide promotes interleukin-10 production in LPS-induced macrophages via upregulating transcription factor Maf and activating PI3K/Akt pathway.
Zhang J, Zhao H, Feng Y, Xu X, Yang Y, Zhang P, Lu Z, Zhang T
International immunopharmacology 2021 Dec;101(Pt A):108264
International immunopharmacology 2021 Dec;101(Pt A):108264
Aggregation-Induced Emission (AIE) Nanoparticles-Assisted NIR-II Fluorescence Imaging-Guided Diagnosis and Surgery for Inflammatory Bowel Disease (IBD).
Fan X, Xia Q, Zhang Y, Li Y, Feng Z, Zhou J, Qi J, Tang BZ, Qian J, Lin H
Advanced healthcare materials 2021 Dec;10(24):e2101043
Advanced healthcare materials 2021 Dec;10(24):e2101043
NuMA regulates mitotic spindle assembly, structural dynamics and function via phase separation.
Sun M, Jia M, Ren H, Yang B, Chi W, Xin G, Jiang Q, Zhang C
Nature communications 2021 Dec 9;12(1):7157
Nature communications 2021 Dec 9;12(1):7157
Uncovering a conserved vulnerability site in SARS-CoV-2 by a human antibody.
Li T, Cai H, Zhao Y, Li Y, Lai Y, Yao H, Liu LD, Sun Z, van Vlissingen MF, Kuiken T, GeurtsvanKessel CH, Zhang N, Zhou B, Lu L, Gong Y, Qin W, Mondal M, Duan B, Xu S, Richard AS, Raoul H, Chen J, Xu C, Wu L, Zhou H, Huang Z, Zhang X, Li J, Wang Y, Bi Y, Rockx B, Chen J, Meng FL, Lavillette D, Li D
EMBO molecular medicine 2021 Dec 7;13(12):e14544
EMBO molecular medicine 2021 Dec 7;13(12):e14544
miR-140-3p enhanced the osteo/odontogenic differentiation of DPSCs via inhibiting KMT5B under hypoxia condition.
Zheng H, Wang N, Li L, Ge L, Jia H, Fan Z
International journal of oral science 2021 Dec 7;13(1):41
International journal of oral science 2021 Dec 7;13(1):41
RND3 attenuates oxidative stress and vascular remodeling in spontaneously hypertensive rat via inhibiting ROCK1 signaling.
Wu N, Zheng F, Li N, Han Y, Xiong XQ, Wang JJ, Chen Q, Li YH, Zhu GQ, Zhou YB
Redox biology 2021 Dec 6;48:102204
Redox biology 2021 Dec 6;48:102204
(20S) Ginsenoside Rh2 Exerts Its Anti-Tumor Effect by Disrupting the HSP90A-Cdc37 System in Human Liver Cancer Cells.
Chen C, Wang YS, Zhang ET, Li GA, Liu WY, Li Y, Jin YH
International journal of molecular sciences 2021 Dec 6;22(23)
International journal of molecular sciences 2021 Dec 6;22(23)
Glucocorticoid receptor regulates PD-L1 and MHC-I in pancreatic cancer cells to promote immune evasion and immunotherapy resistance.
Deng Y, Xia X, Zhao Y, Zhao Z, Martinez C, Yin W, Yao J, Hang Q, Wu W, Zhang J, Yu Y, Xia W, Yao F, Zhao D, Sun Y, Ying H, Hung MC, Ma L
Nature communications 2021 Dec 6;12(1):7041
Nature communications 2021 Dec 6;12(1):7041
Berberrubine attenuates potassium oxonate- and hypoxanthine-induced hyperuricemia by regulating urate transporters and JAK2/STAT3 signaling pathway.
Lin G, Yu Q, Xu L, Huang Z, Mai L, Jiang L, Su Z, Xie J, Li Y, Liu Y, Lin Z, Chen J
European journal of pharmacology 2021 Dec 5;912:174592
European journal of pharmacology 2021 Dec 5;912:174592
Ultrasound triggered topical delivery of Bmp7 mRNA for white fat browning induction via engineered smart exosomes.
Guo Y, Wan Z, Zhao P, Wei M, Liu Y, Bu T, Sun W, Li Z, Yuan L
Journal of nanobiotechnology 2021 Dec 4;19(1):402
Journal of nanobiotechnology 2021 Dec 4;19(1):402
Efficient induction of proximity-dependent labelling by biotin feeding in BMAL1-BioID knock-in mice.
Murata K, Mimura A, Suzuki H, Mikami N, Hamada Y, Kato K, Iki N, Ishida M, Daitoku Y, Tanimoto Y, Okiyoneda T, Fujiyama T, Dinh TTH, Mizuno S, Sugiyama F
Journal of biochemistry 2021 Dec 4;170(4):453-461
Journal of biochemistry 2021 Dec 4;170(4):453-461
USP30-AS1 contributes to mitochondrial quality control in glioblastoma cells.
Wang N, Li J, Xin Q, Xu N
Biochemical and biophysical research communications 2021 Dec 3;581:31-37
Biochemical and biophysical research communications 2021 Dec 3;581:31-37
LRRC4 mediates the formation of circular RNA CD44 to inhibitGBM cell proliferation.
Feng J, Ren X, Fu H, Li D, Chen X, Zu X, Liu Q, Wu M
Molecular therapy. Nucleic acids 2021 Dec 3;26:473-487
Molecular therapy. Nucleic acids 2021 Dec 3;26:473-487
The RNA binding protein QKI5 suppresses ovarian cancer via downregulating transcriptional coactivator TAZ.
Liu T, Yang Y, Xie Z, Luo Q, Yang D, Liu X, Zhao H, Wei Q, Liu Y, Li L, Wang Y, Wang F, Yu J, Xu J, Yu J, Yi P
Molecular therapy. Nucleic acids 2021 Dec 3;26:388-400
Molecular therapy. Nucleic acids 2021 Dec 3;26:388-400
Loss-of-function missense variant of AKAP4 induced male infertility through reduced interaction with QRICH2 during sperm flagella development.
Zhang G, Li D, Tu C, Meng L, Tan Y, Ji Z, Cheng J, Lu G, Lin G, Zhang H, Sun J, Wang M, Du J, Xu W
Human molecular genetics 2021 Dec 27;31(2):219-231
Human molecular genetics 2021 Dec 27;31(2):219-231
6-Thioguanine Inhibits Herpes Simplex Virus 1 Infection of Eyes.
Chen D, Liu Y, Zhang F, You Q, Ma W, Wu J, Wu Z
Microbiology spectrum 2021 Dec 22;9(3):e0064621
Microbiology spectrum 2021 Dec 22;9(3):e0064621
Pan-cancer analysis of N4-acetylcytidine adaptor THUMPD1 as a predictor for prognosis and immunotherapy.
Li K, Liu J, Yang X, Tu Z, Huang K, Zhu X
Bioscience reports 2021 Dec 22;41(12)
Bioscience reports 2021 Dec 22;41(12)
Heat stress affects fetal brain and intestinal function associated with the alterations of placental barrier in late pregnant mouse.
Guo H, Yang Y, Qiao Y, He J, Yao W, Zheng W
Ecotoxicology and environmental safety 2021 Dec 20;227:112916
Ecotoxicology and environmental safety 2021 Dec 20;227:112916
Responses of JNK signaling pathway to the toxic dinoflagellate Prorocentrum lima in the mussel Perna viridis.
Lv JJ, Yuan KK, Lu MY, He ZB, Li HY, Yang WD
Ecotoxicology and environmental safety 2021 Dec 20;227:112905
Ecotoxicology and environmental safety 2021 Dec 20;227:112905
Identification of key genes as predictive biomarkers for osteosarcoma metastasis using translational bioinformatics.
Ding FP, Tian JY, Wu J, Han DF, Zhao D
Cancer cell international 2021 Dec 2;21(1):640
Cancer cell international 2021 Dec 2;21(1):640
A machine learning pipeline revealing heterogeneous responses to drug perturbations on vascular smooth muscle cell spheroid morphology and formation.
Vaidyanathan K, Wang C, Krajnik A, Yu Y, Choi M, Lin B, Jang J, Heo SJ, Kolega J, Lee K, Bae Y
Scientific reports 2021 Dec 2;11(1):23285
Scientific reports 2021 Dec 2;11(1):23285
Anti-tumor effect of polysaccharide from Pleurotus ostreatus on H22 mouse Hepatoma ascites in-vivo and hepatocellular carcinoma in-vitro model.
Khinsar KH, Abdul S, Hussain A, Ud Din R, Lei L, Cao J, Abbasi M, Ur Rehman A, Farooqui N, Yi X, Min H, Wang L, Mintao Z
AMB Express 2021 Dec 2;11(1):160
AMB Express 2021 Dec 2;11(1):160
Pan-cancer multi-omics analyses reveal crosstalk between the Hippo and immune signaling pathways in the tumor microenvironment.
Wang C, Zhu T, Zhao Z, Chen B, Chen T, Dong Q, Liu M, Zhuang S, Yang F, Liu Y, Yang M, Gu Y, Liang H
FEBS letters 2021 Dec 2;
FEBS letters 2021 Dec 2;
WITHDRAWN: Role of microRNA-19b-3p on osteoporosis after experimental spinal cord injury in rats.
Liu D, Lin Z, Huang Y, Qiu M
Archives of biochemistry and biophysics 2021 Dec 15;714:108805
Archives of biochemistry and biophysics 2021 Dec 15;714:108805
A novel protoapigenone analog RY10-4 induces apoptosis of breast cancer cells by exacerbating mitochondrial Ca2+ influx through mitochondrial calcium uniporter.
Xue P, Chen Q, Ren X, Liu D, Yang X
Toxicology and applied pharmacology 2021 Dec 15;433:115776
Toxicology and applied pharmacology 2021 Dec 15;433:115776
miR-126 regulates angiogenesis in myocardial ischemia by targeting HIF-1α.
Gao S, Gao H, Dai L, Han Y, Lei Z, Wang X, Chang H, Liu S, Wang Z, Tong H, Wu H
Experimental cell research 2021 Dec 15;409(2):112925
Experimental cell research 2021 Dec 15;409(2):112925
Synergistic anti-inflammatory activity of apigenin and curcumin co-encapsulated in caseins assessed with lipopolysaccharide-stimulated RAW 264.7 macrophages.
Hong S, Dia VP, Zhong Q
International journal of biological macromolecules 2021 Dec 15;193(Pt A):702-712
International journal of biological macromolecules 2021 Dec 15;193(Pt A):702-712
Intermittent bolus feeding does not enhance protein synthesis, myonuclear accretion, or lean growth more than continuous feeding in a premature piglet model.
Rudar M, Naberhuis JK, Suryawan A, Nguyen HV, Stoll B, Style CC, Verla MA, Olutoye OO, Burrin DG, Fiorotto ML, Davis TA
American journal of physiology. Endocrinology and metabolism 2021 Dec 1;321(6):E737-E752
American journal of physiology. Endocrinology and metabolism 2021 Dec 1;321(6):E737-E752
Role of the hippo signaling pathway in the extracellular matrix degradation of chondrocytes induced by fluoride exposure.
Yu FF, Zuo J, Fu X, Gao MH, Sun L, Yu SY, Li Z, Zhou GY, Ba Y
Ecotoxicology and environmental safety 2021 Dec 1;225:112796
Ecotoxicology and environmental safety 2021 Dec 1;225:112796
Cypermethrin triggers YY1-mediated testosterone biosynthesis suppression.
Liu C, Qu J, Wu M, Huang X, Li L
Ecotoxicology and environmental safety 2021 Dec 1;225:112792
Ecotoxicology and environmental safety 2021 Dec 1;225:112792
Klotho ameliorated cognitive deficits in a temporal lobe epilepsy rat model by inhibiting ferroptosis.
Xiang T, Luo X, Zeng C, Li S, Ma M, Wu Y
Brain research 2021 Dec 1;1772:147668
Brain research 2021 Dec 1;1772:147668
Adipose-derived stem cells (ADSCs) inhibit the expression of anti-apoptosis proteins through up-regulation of ATF4 on breast cancer cells.
Ren J, Kong W, Lu F, Li Y
Annals of translational medicine 2021 Aug;9(16):1300
Annals of translational medicine 2021 Aug;9(16):1300
Glaucocalyxin A induces apoptosis and autophagy in tongue squamous cell carcinoma cells by regulating ROS.
Shi F, Xue D, Jiang Q, Qiu J
Cancer chemotherapy and pharmacology 2021 Aug;88(2):235-246
Cancer chemotherapy and pharmacology 2021 Aug;88(2):235-246
IL-10 ameliorates PM2.5-induced lung injury by activating the AMPK/SIRT1/PGC-1α pathway.
Zhang N, Li P, Lin H, Shuo T, Ping F, Su L, Chen G
Environmental toxicology and pharmacology 2021 Aug;86:103659
Environmental toxicology and pharmacology 2021 Aug;86:103659
Hsa-miR-34a-5p reverses multidrug resistance in gastric cancer cells by targeting the 3'-UTR of SIRT1 and inhibiting its expression.
Deng XJ, Zheng HL, Ke XQ, Deng M, Ma ZZ, Zhu Y, Cui YY
Cellular signalling 2021 Aug;84:110016
Cellular signalling 2021 Aug;84:110016
CircZNF208 enhances the sensitivity to X-rays instead of carbon-ions through the miR-7-5p /SNCA signal axis in non-small-cell lung cancer cells.
Liu B, Li H, Liu X, Li F, Chen W, Kuang Y, Zhao X, Li L, Yu B, Jin X, Li Q
Cellular signalling 2021 Aug;84:110012
Cellular signalling 2021 Aug;84:110012
Heat shock protein 90 inhibitor ameliorates pancreatic fibrosis by degradation of transforming growth factor-β receptor.
Peng YF, Lin H, Liu DC, Zhu XY, Huang N, Wei YX, Li L
Cellular signalling 2021 Aug;84:110001
Cellular signalling 2021 Aug;84:110001
The Regulation of Neutrophil Extracellular Trap-induced Tissue Damage by Human CD177.
Yoneyama T, Maeda A, Kogata S, Toyama C, Lo PC, Masahata K, Kamiyama M, Haneda T, Okamatu C, Eguchi H, Tazuke Y, Ueno T, Okuyama H, Miyagawa S
Transplantation direct 2021 Aug;7(8):e734
Transplantation direct 2021 Aug;7(8):e734
6-Shogaol from ginger shows anti-tumor effect in cervical carcinoma via PI3K/Akt/mTOR pathway.
Pei XD, He ZL, Yao HL, Xiao JS, Li L, Gu JZ, Shi PZ, Wang JH, Jiang LH
European journal of nutrition 2021 Aug;60(5):2781-2793
European journal of nutrition 2021 Aug;60(5):2781-2793
microRNA-4429-5p suppresses the malignant development of colon cancer by targeting matrix metalloproteinase 16.
Li W, Song Z, Jia N, Zhang C, Gao W, Wang L
In vitro cellular & developmental biology. Animal 2021 Aug;57(7):715-725
In vitro cellular & developmental biology. Animal 2021 Aug;57(7):715-725
ROBO2 hampers malignant biological behavior and predicts a better prognosis in pancreatic adenocarcinoma.
Ding C, Li Y, Wang S, Xing C, Chen L, Zhang H, Wang Y, Dai M
Scandinavian journal of gastroenterology 2021 Aug;56(8):955-964
Scandinavian journal of gastroenterology 2021 Aug;56(8):955-964
Effect of electro-acupuncture at ST 36 on maternal food restriction-induced lung phenotype in rat offspring.
Mou Q, Ji B, Zhao G, Liu Y, Sakurai R, Xie Y, Zhang Q, Dai J, Lu Y, Ge Y, Shi T, Xu S, Rehan VK
Pediatric pulmonology 2021 Aug;56(8):2537-2545
Pediatric pulmonology 2021 Aug;56(8):2537-2545
Comparison of the biological and functional characteristics of mesenchymal stem cells from intrahepatic and identical bone marrow.
Lai J, Jiang S, Shuai L, Zhang Y, Xia R, Chen Q, Bai L
Stem cell research 2021 Aug;55:102477
Stem cell research 2021 Aug;55:102477
Establishment of two homozygous CRISPR interference (CRISPRi) knock-in human induced pluripotent stem cell (hiPSC) lines for titratable endogenous gene repression.
Schoger E, Zimmermann WH, Cyganek L, Zelarayán LC
Stem cell research 2021 Aug;55:102473
Stem cell research 2021 Aug;55:102473
Base editing-mediated perturbation of endogenous PKM1/2 splicing facilitates isoform-specific functional analysis in vitro and in vivo.
Lin J, Wu S, Shen Q, Liu J, Huang S, Peng G, Qiao Y
Cell proliferation 2021 Aug;54(8):e13096
Cell proliferation 2021 Aug;54(8):e13096
Loss of microRNA-147 function alleviates synovial inflammation through ZNF148 in rheumatoid and experimental arthritis.
Jiang C, Wu X, Li X, Li M, Zhang W, Tao P, Xu J, Ren X, Mo L, Guo Y, Wang S, Geng M, Zhang F, Tian J, Zhu W, Meng L, Lu S
European journal of immunology 2021 Aug;51(8):2062-2073
European journal of immunology 2021 Aug;51(8):2062-2073
DJ-1 activates the noncanonical NF-κB pathway via interaction with Cezanne to inhibit the apoptosis and promote the proliferation of Ishikawa cells.
Zhu QZ, Liu HY, Zhao XY, Qiu LJ, Zhou TT, Wang XY, Chen HP, Xiao ZQ
Molecular biology reports 2021 Aug;48(8):6075-6083
Molecular biology reports 2021 Aug;48(8):6075-6083
Long noncoding RNA uc003pxg.1 regulates endothelial cell proliferation and migration via miR‑25‑5p in coronary artery disease.
Li P, Li Y, Chen L, Ma X, Yan X, Yan M, Qian B, Wang F, Xu J, Yin J, Xu G, Sun K
International journal of molecular medicine 2021 Aug;48(2)
International journal of molecular medicine 2021 Aug;48(2)
Increased AT1 receptor expression mediates vasoconstriction leading to hypertension in Snx1-/- mice.
Liu C, Li X, Fu J, Chen K, Liao Q, Wang J, Chen C, Luo H, Jose PA, Yang Y, Yang J, Zeng C
Hypertension research : official journal of the Japanese Society of Hypertension 2021 Aug;44(8):906-917
Hypertension research : official journal of the Japanese Society of Hypertension 2021 Aug;44(8):906-917
Downregulation of glucose-6-phosphatase expression contributes to fluoxetine-induced hepatic steatosis.
Lu S, Ma Z, Gu Y, Li P, Chen Y, Bai M, Zhou H, Yang X, Jiang H
Journal of applied toxicology : JAT 2021 Aug;41(8):1232-1240
Journal of applied toxicology : JAT 2021 Aug;41(8):1232-1240
Chromium (VI) promotes EMT by regulating FLNA in BLCA.
Sheng F, Chen KX, Liu J, Li JX, Liang GH, Xu Y, Du E, Zhang ZH
Environmental toxicology 2021 Aug;36(8):1694-1701
Environmental toxicology 2021 Aug;36(8):1694-1701
Rearrangement of Actin Cytoskeleton by Zika Virus Infection Facilitates Blood-Testis Barrier Hyperpermeability.
Nie Y, Hui L, Guo M, Yang W, Huang R, Chen J, Wen X, Zhao M, Wu Y
Virologica Sinica 2021 Aug;36(4):692-705
Virologica Sinica 2021 Aug;36(4):692-705
Endothelial neuropilin-2 influences angiogenesis by regulating actin pattern development and α5-integrin-p-FAK complex recruitment to assembling adhesion sites.
Benwell CJ, Taylor JAGE, Robinson SD
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 Aug;35(8):e21679
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 Aug;35(8):e21679
Salidroside protects cardiac function in mice with diabetic cardiomyopathy via activation of mitochondrial biogenesis and SIRT3.
Li Y, Wei X, Liu SL, Zhao Y, Jin S, Yang XY
Phytotherapy research : PTR 2021 Aug;35(8):4579-4591
Phytotherapy research : PTR 2021 Aug;35(8):4579-4591
RNA m6A modification orchestrates a LINE-1-host interaction that facilitates retrotransposition and contributes to long gene vulnerability.
Xiong F, Wang R, Lee JH, Li S, Chen SF, Liao Z, Hasani LA, Nguyen PT, Zhu X, Krakowiak J, Lee DF, Han L, Tsai KL, Liu Y, Li W
Cell research 2021 Aug;31(8):861-885
Cell research 2021 Aug;31(8):861-885
Inhibition of hepatitis E virus replication by zinc-finger antiviral Protein synergizes with IFN-β.
Yu W, Ji H, Long F, Chen S, He Q, Xia Y, Cong C, Yang C, Wei D, Huang F
Journal of viral hepatitis 2021 Aug;28(8):1219-1229
Journal of viral hepatitis 2021 Aug;28(8):1219-1229
GINS2 promotes EMT in pancreatic cancer via specifically stimulating ERK/MAPK signaling.
Huang L, Chen S, Fan H, Ji D, Chen C, Sheng W
Cancer gene therapy 2021 Aug;28(7-8):839-849
Cancer gene therapy 2021 Aug;28(7-8):839-849
Lys694Arg polymorphism leads to blunted responses to LPS by interfering TLR4 with recruitment of MyD88.
Yang Y, Hu Y, Zhou Y, Liang T, Tang H, Ju H, Shi Q, Fang H
Innate immunity 2021 Aug;27(6):483-492
Innate immunity 2021 Aug;27(6):483-492
Genotype-dependent epigenetic regulation of DLGAP2 in alcohol use and dependence.
Meng W, Sjöholm LK, Kononenko O, Tay N, Zhang D, Sarkisyan D, Geske JR, Ing A, Qiu W, Watanabe H, Almamoun R, Frieling H, Bleich S, Cui D, Biernacka JM, Mayfield RD, Dang Y, Karpyak VM, Schumann G, IMAGEN Consortium., Bakalkin G, Ekström TJ, Rüegg J, Liu Y
Molecular psychiatry 2021 Aug;26(8):4367-4382
Molecular psychiatry 2021 Aug;26(8):4367-4382
Helicobacter pylori induces gastric cancer via down-regulating miR-375 to inhibit dendritic cell maturation.
Zhang Z, Chen S, Fan M, Ruan G, Xi T, Zheng L, Guo L, Ye F, Xing Y
Helicobacter 2021 Aug;26(4):e12813
Helicobacter 2021 Aug;26(4):e12813
Vimentin rearrangement by phosphorylation is beneficial for porcine reproductive and respiratory syndrome virus replication in vitro.
Zheng XX, Li R, Qiao S, Chen XX, Zhang L, Lu Q, Xing G, Zhou EM, Zhang G
Veterinary microbiology 2021 Aug;259:109133
Veterinary microbiology 2021 Aug;259:109133
EGCG synergizes the therapeutic effect of irinotecan through enhanced DNA damage in human colorectal cancer cells.
Wu W, Dong J, Gou H, Geng R, Yang X, Chen D, Xiang B, Zhang Z, Ren S, Chen L, Liu J
Journal of cellular and molecular medicine 2021 Aug;25(16):7913-7921
Journal of cellular and molecular medicine 2021 Aug;25(16):7913-7921
Ring finger protein 19A is overexpressed in non-small cell lung cancer and mediates p53 ubiquitin-degradation to promote cancer growth.
Cheng Y, Hu Y, Wang H, Zhao Z, Jiang X, Zhang Y, Zhang J, Tong Y, Qiu X
Journal of cellular and molecular medicine 2021 Aug;25(16):7796-7808
Journal of cellular and molecular medicine 2021 Aug;25(16):7796-7808
Propofol attenuates renal ischemia/reperfusion injury by regulating the MALAT1/miR-126-5p axis.
Li X, Zhang Z, Li A, Hu Y
The journal of gene medicine 2021 Aug;23(8):e3349
The journal of gene medicine 2021 Aug;23(8):e3349
ASTE1 promotes shieldin-complex-mediated DNA repair by attenuating end resection.
Zhao F, Kim W, Gao H, Liu C, Zhang Y, Chen Y, Deng M, Zhou Q, Huang J, Hu Q, Chen SH, Nowsheen S, Kloeber JA, Qin B, Yin P, Tu X, Guo G, Qin S, Zhang C, Gao M, Luo K, Liu Y, Lou Z, Yuan J
Nature cell biology 2021 Aug;23(8):894-904
Nature cell biology 2021 Aug;23(8):894-904
Decreased TMEM40 expression is associated with malignant behavior of cutaneous squamous cell carcinoma and inhibits tumor progression.
Yu L, Liu J, Zhang TD, Zheng XF, Luo DL, Zhu WL, Qiu XW, Guo LL
Oncology letters 2021 Aug;22(2):606
Oncology letters 2021 Aug;22(2):606
Indoleamine 2,3-Dioxygenase 1 (IDO1) Promotes Cardiac Hypertrophy via a PI3K-AKT-mTOR-Dependent Mechanism.
Liu Y, Li S, Gao Z, Li S, Tan Q, Li Y, Wang D, Wang Q
Cardiovascular toxicology 2021 Aug;21(8):655-668
Cardiovascular toxicology 2021 Aug;21(8):655-668
A γ-adducin cleavage fragment induces neurite deficits and synaptic dysfunction in Alzheimer's disease.
Xiong M, Zou L, Meng L, Zhang X, Tian Y, Zhang G, Yang J, Chen G, Xiong J, Ye K, Zhang Z
Progress in neurobiology 2021 Aug;203:102074
Progress in neurobiology 2021 Aug;203:102074
Investigating the nature of active forces in tissues reveals how contractile cells can form extensile monolayers.
Balasubramaniam L, Doostmohammadi A, Saw TB, Narayana GHNS, Mueller R, Dang T, Thomas M, Gupta S, Sonam S, Yap AS, Toyama Y, Mège RM, Yeomans JM, Ladoux B
Nature materials 2021 Aug;20(8):1156-1166
Nature materials 2021 Aug;20(8):1156-1166
MiR-532-3p suppresses cell viability, migration and invasion of clear cell renal cell carcinoma through targeting TROAP.
Gao B, Wang L, Zhang Y, Zhang N, Han M, Liu H, Sun D, Liu Y
Cell cycle (Georgetown, Tex.) 2021 Aug;20(16):1578-1588
Cell cycle (Georgetown, Tex.) 2021 Aug;20(16):1578-1588
Nitazoxanide impairs mitophagy flux through ROS-mediated mitophagy initiation and lysosomal dysfunction in bladder cancer.
Sun H, Ou T, Hu J, Yang Z, Lei Q, Li Y, Wang G, Li Y, Wu K, Wang S, Wu S
Biochemical pharmacology 2021 Aug;190:114588
Biochemical pharmacology 2021 Aug;190:114588
Depletion of CIP2A inhibits the proliferation, migration, invasion and epithelial-mesenchymal transition of glioma cells.
Xu Z, Chen X, Hegazy AM, Zhang S, Liu X, Tian J, Wu J, Shi F, Li L, Niu X, Pu J
Brain research bulletin 2021 Aug;173:14-21
Brain research bulletin 2021 Aug;173:14-21
The role of circTmeff-1 in incubation of context-induced morphine craving.
Yu H, Xie B, Zhang J, Luo Y, Galaj E, Zhang X, Shen Q, Liu Y, Cong B, Wen D, Ma C
Pharmacological research 2021 Aug;170:105722
Pharmacological research 2021 Aug;170:105722
High-throughput screening and genome-wide analyses of 44 anticancer drugs in the 1000 Genomes cell lines reveals an association of the NQO1 gene with the response of multiple anticancer drugs.
Akhtari FS, Green AJ, Small GW, Havener TM, House JS, Roell KR, Reif DM, McLeod HL, Wiltshire T, Motsinger-Reif AA
PLoS genetics 2021 Aug;17(8):e1009732
PLoS genetics 2021 Aug;17(8):e1009732
PtdIns4P restriction by hydrolase SAC1 decides specific fusion of autophagosomes with lysosomes.
Zhang H, Zhou J, Xiao P, Lin Y, Gong X, Liu S, Xu Q, Wang M, Ren H, Lu M, Wang Y, Zhu J, Xie Z, Li H, Lu K
Autophagy 2021 Aug;17(8):1907-1917
Autophagy 2021 Aug;17(8):1907-1917
Classical swine fever virus infection suppresses claudin-1 expression to facilitate its replication in PK-15 cells.
Wang X, Yang Y, Yang X, Liu X, Wang X, Gao L, Yang C, Lan R, Bi J, Zhao Q, Yang G, Wang J, Lin Y, Liu J, Yin G
Microbial pathogenesis 2021 Aug;157:105012
Microbial pathogenesis 2021 Aug;157:105012
Stabilization of Nrf2 leading to HO-1 activation protects against zinc oxide nanoparticles-induced endothelial cell death.
Zhang L, Zou L, Jiang X, Cheng S, Zhang J, Qin X, Qin Z, Chen C, Zou Z
Nanotoxicology 2021 Aug;15(6):779-797
Nanotoxicology 2021 Aug;15(6):779-797
Bavachin enhances NLRP3 inflammasome activation induced by ATP or nigericin and causes idiosyncratic hepatotoxicity.
Qin N, Xu G, Wang Y, Zhan X, Gao Y, Wang Z, Fu S, Shi W, Hou X, Wang C, Li R, Liu Y, Wang J, Zhao H, Xiao X, Bai Z
Frontiers of medicine 2021 Aug;15(4):594-607
Frontiers of medicine 2021 Aug;15(4):594-607
Expression of ISL1 and its partners in prostate cancer progression and neuroendocrine differentiation.
Alshalalfa M, Abou-Ouf H, Davicioni E, Karnes RJ, Alhajj R, Bismar TA
Journal of cancer research and clinical oncology 2021 Aug;147(8):2223-2231
Journal of cancer research and clinical oncology 2021 Aug;147(8):2223-2231
MD2 blockage prevents the migration and invasion of hepatocellular carcinoma cells via inhibition of the EGFR signaling pathway.
Qi Y, Fang Q, Li Q, Ding H, Shu Q, Hu Y, Xin W, Fang L
Journal of gastrointestinal oncology 2021 Aug;12(4):1873-1883
Journal of gastrointestinal oncology 2021 Aug;12(4):1873-1883
miR-744-5p suppresses tumor proliferation and metastasis by targeting transforming growth factor-beta 1 (TGF-β1) in hepatocellular carcinoma (HCC).
Huang W, Chen Q, Dai J, Zhang Y, Yi Y, Wei X, Wu Z
Journal of gastrointestinal oncology 2021 Aug;12(4):1811-1822
Journal of gastrointestinal oncology 2021 Aug;12(4):1811-1822
XPA serves as an autophagy and apoptosis inducer by suppressing hepatocellular carcinoma in a PI3K/Akt/mTOR dependent manner.
Deng Y, Chen QS, Huang WF, Dai JW, Wu ZJ
Journal of gastrointestinal oncology 2021 Aug;12(4):1797-1810
Journal of gastrointestinal oncology 2021 Aug;12(4):1797-1810
Vitamin D alleviates hypoxia/reoxygenation-induced injury of human trophoblast HTR-8 cells by activating autophagy.
Pi Y, Tian X, Ma J, Zhang H, Huang X
Placenta 2021 Aug;111:10-18
Placenta 2021 Aug;111:10-18
TRIM27 contributes to glomerular endothelial cell injury in lupus nephritis by mediating the FoxO1 signaling pathway.
Liu J, Xu J, Huang J, Gu C, Liu Q, Zhang W, Gao F, Tian Y, Miao X, Zhu Z, Jia B, Tian Y, Wu L, Zhao H, Feng X, Liu S
Laboratory investigation; a journal of technical methods and pathology 2021 Aug;101(8):983-997
Laboratory investigation; a journal of technical methods and pathology 2021 Aug;101(8):983-997
AHR mediates the aflatoxin B1 toxicity associated with hepatocellular carcinoma.
Zhu Q, Ma Y, Liang J, Wei Z, Li M, Zhang Y, Liu M, He H, Qu C, Cai J, Wang X, Zeng Y, Jiao Y
Signal transduction and targeted therapy 2021 Aug 9;6(1):299
Signal transduction and targeted therapy 2021 Aug 9;6(1):299
Bcl-2-associated transcription factor 1 Ser290 phosphorylation mediates DNA damage response and regulates radiosensitivity in gastric cancer.
Liu J, Li J, Sun Z, Duan Y, Wang F, Wei G, Yang JH
Journal of translational medicine 2021 Aug 9;19(1):339
Journal of translational medicine 2021 Aug 9;19(1):339
Autophagy-associated circular RNA hsa_circ_0007813 modulates human bladder cancer progression via hsa-miR-361-3p/IGF2R regulation.
Zhang Z, Mou Z, Xu C, Wu S, Dai X, Chen X, Ou Y, Chen Y, Yang C, Jiang H
Cell death & disease 2021 Aug 7;12(8):778
Cell death & disease 2021 Aug 7;12(8):778
MiR-133a-3p inhibits scar formation in scalded mice and suppresses the proliferation and migration of scar derived-fibroblasts by targeting connective tissue growth factor.
Hirman AR, Du L, Cheng S, Zheng H, Duo L, Zhai Q, Xu J
Experimental animals 2021 Aug 6;70(3):322-332
Experimental animals 2021 Aug 6;70(3):322-332
miR-145-5p attenuates inflammatory response and apoptosis in myocardial ischemia-reperfusion injury by inhibiting (NADPH) oxidase homolog 1.
Tan L, Liu L, Yao J, Piao C
Experimental animals 2021 Aug 6;70(3):311-321
Experimental animals 2021 Aug 6;70(3):311-321
Cofilin-1 promotes fibrocyte differentiation and contributes to pulmonary fibrosis.
Guo W, Guo T, Zhou Q, Long Y, Luo M, Shen Q, Duan W, Ouyang X, Peng H
Biochemical and biophysical research communications 2021 Aug 6;565:43-49
Biochemical and biophysical research communications 2021 Aug 6;565:43-49
Human CD4+ T-Cell Clone Expansion Leads to the Expression of the Cysteine Peptidase Inhibitor Cystatin F.
Perišić Nanut M, Pawelec G, Kos J
International journal of molecular sciences 2021 Aug 5;22(16)
International journal of molecular sciences 2021 Aug 5;22(16)
RNA-binding protein RBM47 stabilizes IFNAR1 mRNA to potentiate host antiviral activity.
Wang K, Huang C, Jiang T, Chen Z, Xue M, Zhang Q, Zhang J, Dai J
EMBO reports 2021 Aug 4;22(8):e52205
EMBO reports 2021 Aug 4;22(8):e52205
Rpsa Signaling Regulates Cortical Neuronal Morphogenesis via Its Ligand, PEDF, and Plasma Membrane Interaction Partner, Itga6.
Blazejewski SM, Bennison SA, Ha NT, Liu X, Smith TH, Dougherty KJ, Toyo-Oka K
Cerebral cortex (New York, N.Y. : 1991) 2021 Aug 4;
Cerebral cortex (New York, N.Y. : 1991) 2021 Aug 4;
The application of CRISPR/Cas9 system in cervical carcinogenesis.
Gao C, Wu P, Yu L, Liu L, Liu H, Tan X, Wang L, Huang X, Wang H
Cancer gene therapy 2021 Aug 4;
Cancer gene therapy 2021 Aug 4;
PKCε controls the fusion of secretory vesicles in mast cells in a phosphatidic acid-dependent mode.
Serrano-López EM, López-Martínez D, Gómez-Fernández JC, Egea-Jiménez AL, Corbalán-García S
International journal of biological macromolecules 2021 Aug 31;185:377-389
International journal of biological macromolecules 2021 Aug 31;185:377-389
Pericentromeric noncoding RNA changes DNA binding of CTCF and inflammatory gene expression in senescence and cancer.
Miyata K, Imai Y, Hori S, Nishio M, Loo TM, Okada R, Yang L, Nakadai T, Maruyama R, Fujii R, Ueda K, Jiang L, Zheng H, Toyokuni S, Sakata T, Shirahige K, Kojima R, Nakayama M, Oshima M, Nagayama S, Seimiya H, Hirota T, Saya H, Hara E, Takahashi A
Proceedings of the National Academy of Sciences of the United States of America 2021 Aug 31;118(35)
Proceedings of the National Academy of Sciences of the United States of America 2021 Aug 31;118(35)
Tenascin-C Participates Pulmonary Injury Induced by Paraquat Through Regulating TLR4 and TGF-β Signaling Pathways.
Zhang D, Liu Z, Liu Q, Lan H, Peng J, Liu X, Liu W
Inflammation 2021 Aug 31;
Inflammation 2021 Aug 31;
UBE2T promotes autophagy via the p53/AMPK/mTOR signaling pathway in lung adenocarcinoma.
Zhu J, Ao H, Liu M, Cao K, Ma J
Journal of translational medicine 2021 Aug 30;19(1):374
Journal of translational medicine 2021 Aug 30;19(1):374
Enriched environment remedies cognitive dysfunctions and synaptic plasticity through NMDAR-Ca2+-Activin A circuit in chronic cerebral hypoperfusion rats.
Zhang X, Shi X, Wang J, Xu Z, He J
Aging 2021 Aug 30;13(16):20748-20761
Aging 2021 Aug 30;13(16):20748-20761
AEG-1 silencing attenuates M2-polarization of glioma-associated microglia/macrophages and sensitizes glioma cells to temozolomide.
Li J, Sun Y, Sun X, Zhao X, Ma Y, Wang Y, Zhang X
Scientific reports 2021 Aug 30;11(1):17348
Scientific reports 2021 Aug 30;11(1):17348
BGP-15 Inhibits Hyperglycemia-Aggravated VSMC Calcification Induced by High Phosphate.
Nagy A, Pethő D, Gesztelyi R, Juhász B, Balla G, Szilvássy Z, Balla J, Gáll T
International journal of molecular sciences 2021 Aug 26;22(17)
International journal of molecular sciences 2021 Aug 26;22(17)
Efficient intracellular delivery of proteins by a multifunctional chimaeric peptide in vitro and in vivo.
Yu S, Yang H, Li T, Pan H, Ren S, Luo G, Jiang J, Yu L, Chen B, Zhang Y, Wang S, Tian R, Zhang T, Zhang S, Chen Y, Yuan Q, Ge S, Zhang J, Xia N
Nature communications 2021 Aug 26;12(1):5131
Nature communications 2021 Aug 26;12(1):5131
Autophagy Inhibition Plays a Protective Role in Ferroptosis Induced by Alcohol via the p62-Keap1-Nrf2 Pathway.
Zhao Y, Lu J, Mao A, Zhang R, Guan S
Journal of agricultural and food chemistry 2021 Aug 25;69(33):9671-9683
Journal of agricultural and food chemistry 2021 Aug 25;69(33):9671-9683
SESN2 protects against denervated muscle atrophy through unfolded protein response and mitophagy.
Yang X, Xue P, Yuan M, Xu X, Wang C, Li W, Machens HG, Chen Z
Cell death & disease 2021 Aug 24;12(9):805
Cell death & disease 2021 Aug 24;12(9):805
Biallelic SYNE2 Missense Mutations Leading to Nesprin-2 Giant Hypo-Expression Are Associated with Intellectual Disability and Autism.
Young N, Asif M, Jackson M, Fernández-Mayoralas DM, de la Peña MJ, Calleja-Pérez B, Álvarez S, Hunter-Featherstone E, Noegel AA, Höhne W, Nürnberg P, Obara B, Hussain MS, Karakesisoglou I, Fernández-Jaén A
Genes 2021 Aug 24;12(9)
Genes 2021 Aug 24;12(9)
Ten-eleven translocation 1 mediated-DNA hydroxymethylation is required for myelination and remyelination in the mouse brain.
Zhang M, Wang J, Zhang K, Lu G, Liu Y, Ren K, Wang W, Xin D, Xu L, Mao H, Xing J, Gao X, Jin W, Berry K, Mikoshiba K, Wu S, Lu QR, Zhao X
Nature communications 2021 Aug 24;12(1):5091
Nature communications 2021 Aug 24;12(1):5091
Autophagic elimination of ribosomes during spermiogenesis provides energy for flagellar motility.
Lei Y, Zhang X, Xu Q, Liu S, Li C, Jiang H, Lin H, Kong E, Liu J, Qi S, Li H, Xu W, Lu K
Developmental cell 2021 Aug 23;56(16):2313-2328.e7
Developmental cell 2021 Aug 23;56(16):2313-2328.e7
Helicobacter urease suppresses cytotoxic CD8+ T-cell responses through activating Myh9-dependent induction of PD-L1.
Wu J, Zhu X, Guo X, Yang Z, Cai Q, Gu D, Luo W, Yuan C, Xiang Y
International immunology 2021 Aug 23;33(9):491-504
International immunology 2021 Aug 23;33(9):491-504
A single genetic locus controls both expression of DPEP1/CHMP1A and kidney disease development via ferroptosis.
Guan Y, Liang X, Ma Z, Hu H, Liu H, Miao Z, Linkermann A, Hellwege JN, Voight BF, Susztak K
Nature communications 2021 Aug 23;12(1):5078
Nature communications 2021 Aug 23;12(1):5078
Engineered basic fibroblast growth factor-overexpressing human umbilical cord-derived mesenchymal stem cells improve the proliferation and neuronal differentiation of endogenous neural stem cells and functional recovery of spinal cord injury by activating the PI3K-Akt-GSK-3β signaling pathway.
Huang F, Gao T, Wang W, Wang L, Xie Y, Tai C, Liu S, Cui Y, Wang B
Stem cell research & therapy 2021 Aug 21;12(1):468
Stem cell research & therapy 2021 Aug 21;12(1):468
Sodium valproate increases activity of the sirtuin pathway resulting in beneficial effects for spinocerebellar ataxia-3 in vivo.
Watchon M, Luu L, Robinson KJ, Yuan KC, De Luca A, Suddull HJ, Tym MC, Guillemin GJ, Cole NJ, Nicholson GA, Chung RS, Lee A, Laird AS
Molecular brain 2021 Aug 20;14(1):128
Molecular brain 2021 Aug 20;14(1):128
UHPLC-MS-based metabolomics and chemoinformatics study reveals the neuroprotective effect and chemical characteristic in Parkinson's disease mice after oral administration of Wen-Shen-Yang-Gan decoction.
Zhu G, Wang W, Chen C, Tang L, Liang Y, Zhang Z, Lu Y, Zhao Y
Aging 2021 Aug 2;13(15):19510-19528
Aging 2021 Aug 2;13(15):19510-19528
Kaempferol attenuates diquat-induced oxidative damage and apoptosis in intestinal porcine epithelial cells.
Jin Y, Zhai Z, Jia H, Lai J, Si X, Wu Z
Food & function 2021 Aug 2;12(15):6889-6899
Food & function 2021 Aug 2;12(15):6889-6899
Enhancer RNA m6A methylation facilitates transcriptional condensate formation and gene activation.
Lee JH, Wang R, Xiong F, Krakowiak J, Liao Z, Nguyen PT, Moroz-Omori EV, Shao J, Zhu X, Bolt MJ, Wu H, Singh PK, Bi M, Shi CJ, Jamal N, Li G, Mistry R, Jung SY, Tsai KL, Ferreon JC, Stossi F, Caflisch A, Liu Z, Mancini MA, Li W
Molecular cell 2021 Aug 19;81(16):3368-3385.e9
Molecular cell 2021 Aug 19;81(16):3368-3385.e9
Repurposing of glycine transport inhibitors for the treatment of erythropoietic protoporphyria.
Halloy F, Iyer PS, Ghidini A, Lysenko V, Barman-Aksözen J, Grubenmann CP, Jucker J, Wildner-Verhey van Wijk N, Ruepp MD, Minder EI, Minder AE, Schneider-Yin X, Theocharides APA, Schümperli D, Hall J
Cell chemical biology 2021 Aug 19;28(8):1221-1234.e6
Cell chemical biology 2021 Aug 19;28(8):1221-1234.e6
Gastrin exerts a protective effect against myocardial infarction via promoting angiogenesis.
Fu J, Tang Y, Zhang Z, Tong L, Yue R, Cai L
Molecular medicine (Cambridge, Mass.) 2021 Aug 19;27(1):90
Molecular medicine (Cambridge, Mass.) 2021 Aug 19;27(1):90
Infection with Human Papillomavirus 18 Promotes Alkylating Agent-Induced Malignant Transformation in a Human Esophageal Cell Line.
Zhang Y, Li Y, Pan E, Zhao C, Zhang H, Liu R, Wang S, Pu Y, Yin L
Chemical research in toxicology 2021 Aug 16;34(8):1866-1878
Chemical research in toxicology 2021 Aug 16;34(8):1866-1878
Proof of Gene Doping in a Mouse Model with a Human Erythropoietin Gene Transferred Using an Adenoviral Vector.
Sugasawa T, Nakano T, Fujita SI, Matsumoto Y, Ishihara G, Aoki K, Yanazawa K, Ono S, Tamai S, Manevich L, Ueda H, Ishibashi N, Tamai K, Kanki Y, Yoshida Y, Watanabe K, Takemasa T, Kawakami Y, Takekoshi K
Genes 2021 Aug 16;12(8)
Genes 2021 Aug 16;12(8)
Tubeimoside I protects against sepsis-induced cardiac dysfunction via SIRT3.
Cheng Z, Lv D, Luo M, Wang R, Guo Y, Yang X, Huang L, Li X, Li C, Shang FF, Huang B, Shen J, Luo S, Yan J
European journal of pharmacology 2021 Aug 15;905:174186
European journal of pharmacology 2021 Aug 15;905:174186
Silencing of RSPO1 mitigates obesity-related renal fibrosis in mice by deactivating Wnt/β-catenin pathway.
Su X, Zhou G, Tian M, Wu S, Wang Y
Experimental cell research 2021 Aug 15;405(2):112713
Experimental cell research 2021 Aug 15;405(2):112713
Long-term exposure to environmental level of phenanthrene causes adaptive immune response and fibrosis in mouse kidneys.
Ruan F, Wu L, Yin H, Fang L, Tang C, Huang S, Fang L, Zuo Z, He C, Huang J
Environmental pollution (Barking, Essex : 1987) 2021 Aug 15;283:117028
Environmental pollution (Barking, Essex : 1987) 2021 Aug 15;283:117028
Itpr1 regulates the formation of anterior eye segment tissues derived from neural crest cells.
Kinoshita A, Ohyama K, Tanimura S, Matsuda K, Kishino T, Negishi Y, Asahina N, Shiraishi H, Hosoki K, Tomiwa K, Ishihara N, Mishima H, Mori R, Nakashima M, Saitoh S, Yoshiura KI
Development (Cambridge, England) 2021 Aug 15;148(16)
Development (Cambridge, England) 2021 Aug 15;148(16)
HPV16 E6 enhances the radiosensitivity in HPV-positive human head and neck squamous cell carcinoma by regulating the miR-27a-3p/SMG1 axis.
Long D, Xu L, Deng Z, Guo D, Zhang Y, Liu Z, Zhang C
Infectious agents and cancer 2021 Aug 13;16(1):56
Infectious agents and cancer 2021 Aug 13;16(1):56
Targeted Ablation of Primary Cilia in Differentiated Dopaminergic Neurons Reduces Striatal Dopamine and Responsiveness to Metabolic Stress.
Mustafa R, Rawas C, Mannal N, Kreiner G, Spittau B, Kamińska K, Yilmaz R, Pötschke C, Kirsch J, Liss B, Tucker KL, Parlato R
Antioxidants (Basel, Switzerland) 2021 Aug 13;10(8)
Antioxidants (Basel, Switzerland) 2021 Aug 13;10(8)
Loss of Smad4 promotes aggressive lung cancer metastasis by de-repression of PAK3 via miRNA regulation.
Tan X, Tong L, Li L, Xu J, Xie S, Ji L, Fu J, Liu Q, Shen S, Liu Y, Xiao Y, Gao F, Moses RE, Bardeesy N, Wang Y, Zhang J, Tang L, Li L, Wong KK, Song D, Yang X, Liu J, Li X
Nature communications 2021 Aug 11;12(1):4853
Nature communications 2021 Aug 11;12(1):4853
Inhibition of DNA methylation de-represses peroxisome proliferator-activated receptor-γ and attenuates pulmonary fibrosis.
Wei A, Gao Q, Chen F, Zhu X, Chen X, Zhang L, Su X, Dai J, Shi Y, Cao W
British journal of pharmacology 2021 Aug 11;
British journal of pharmacology 2021 Aug 11;
Serum exosomal pregnancy zone protein as a promising biomarker in inflammatory bowel disease.
Shao J, Jin Y, Shao C, Fan H, Wang X, Yang G
Cellular & molecular biology letters 2021 Aug 10;26(1):36
Cellular & molecular biology letters 2021 Aug 10;26(1):36
Rab1A promotes cell proliferation and migration by upregulating Gli1 in colorectal cancer.
Peng C, Li X, Ye Z, Wu W
Scientific reports 2021 Aug 10;11(1):16243
Scientific reports 2021 Aug 10;11(1):16243
The Cell-Permeable Derivative of the Immunoregulatory Metabolite Itaconate, 4-Octyl Itaconate, Is Anti-Fibrotic in Systemic Sclerosis.
Henderson J, Dayalan Naidu S, Dinkova-Kostova AT, Przyborski S, Stratton R, O Reilly S
Cells 2021 Aug 10;10(8)
Cells 2021 Aug 10;10(8)
Humanin Alleviates Insulin Resistance in Polycystic Ovary Syndrome: A Human and Rat Model-Based Study.
Wang Y, Zeng Z, Zhao S, Tang L, Yan J, Li N, Zou L, Fan X, Xu C, Huang J, Xia W, Zhu C, Rao M
Endocrinology 2021 Aug 1;162(8)
Endocrinology 2021 Aug 1;162(8)
TSH Activates Macrophage Inflammation by G13- and G15-dependent Pathways.
Yang C, He Z, Zhang Q, Lu M, Zhao J, Chen W, Gao L
Endocrinology 2021 Aug 1;162(8)
Endocrinology 2021 Aug 1;162(8)
LncRNA ABCC6P1 promotes proliferation and migration of papillary thyroid cancer cells via Wnt/β-catenin signaling pathway.
Guan Y, Li Y, Yang QB, Yu J, Qiao H
Annals of translational medicine 2021 Apr;9(8):664
Annals of translational medicine 2021 Apr;9(8):664
ESM1 promotes triple-negative breast cancer cell proliferation through activating AKT/NF-κB/Cyclin D1 pathway.
Liu W, Yang Y, He B, Ma F, Sun F, Guo M, Zhang M, Dong Z
Annals of translational medicine 2021 Apr;9(7):533
Annals of translational medicine 2021 Apr;9(7):533
hucMSCs transplantation promotes locomotor function recovery, reduces apoptosis and inhibits demyelination after SCI in rats.
Liao Z, Yang X, Wang W, Deng W, Zhang Y, Song A, Ni B, Zhao H, Zhang S, Li Z
Neuropeptides 2021 Apr;86:102125
Neuropeptides 2021 Apr;86:102125
Ginsenoside-Rg1 acts as an IDO1 inhibitor, protects against liver fibrosis via alleviating IDO1-mediated the inhibition of DCs maturation.
Mo C, Xie S, Zeng T, Lai Y, Huang S, Zhou C, Yan W, Huang S, Gao L, Lv Z
Phytomedicine : international journal of phytotherapy and phytopharmacology 2021 Apr;84:153524
Phytomedicine : international journal of phytotherapy and phytopharmacology 2021 Apr;84:153524
Bergenin inhibits bladder cancer progression via activating the PPARγ/PTEN/Akt signal pathway.
Liu J, Zhang Y, Yu C, Zhang P, Gu S, Wang G, Xiao H, Li S
Drug development research 2021 Apr;82(2):278-286
Drug development research 2021 Apr;82(2):278-286
Arsenic-induced autophagy regulates apoptosis in AML-12 cells.
Yuan M, Sun Z, Manthari RK, Zhao Y, Guo Q, Yang K, Wang J
Toxicology in vitro : an international journal published in association with BIBRA 2021 Apr;72:105074
Toxicology in vitro : an international journal published in association with BIBRA 2021 Apr;72:105074
LncRNA XIST Promotes Migration and Invasion of Papillary Thyroid Cancer Cell by Modulating MiR-101-3p/CLDN1 Axis.
Du YL, Liang Y, Cao Y, Liu L, Li J, Shi GQ
Biochemical genetics 2021 Apr;59(2):437-452
Biochemical genetics 2021 Apr;59(2):437-452
Mutant IDH1 Enhances Temozolomide Sensitivity via Regulation of the ATM/CHK2 Pathway in Glioma.
Lin L, Cai J, Tan Z, Meng X, Li R, Li Y, Jiang C
Cancer research and treatment 2021 Apr;53(2):367-377
Cancer research and treatment 2021 Apr;53(2):367-377
Morusin inhibits the growth of human colorectal cancer HCT116‑derived sphere‑forming cells via the inactivation of Akt pathway.
Zhou Y, Li X, Ye M
International journal of molecular medicine 2021 Apr;47(4):1
International journal of molecular medicine 2021 Apr;47(4):1
Mono-macrophage-Derived MANF Protects Against Lipopolysaccharide-Induced Acute Kidney Injury via Inhibiting Inflammation and Renal M1 Macrophages.
Hou C, Mei Q, Song X, Bao Q, Li X, Wang D, Shen Y
Inflammation 2021 Apr;44(2):693-703
Inflammation 2021 Apr;44(2):693-703
Aspergillus fumigatus-Stimulated Human Corneal Epithelial Cells Induce Pyroptosis of THP-1 Macrophages by Secreting TSLP.
Ji Q, Wang L, Liu J, Wu Y, Lv H, Wen Y, Shi L, Qu B, Szentmáry N
Inflammation 2021 Apr;44(2):682-692
Inflammation 2021 Apr;44(2):682-692
MiR-32-5p knockdown inhibits epithelial to mesenchymal transition and renal fibrosis by targeting SMAD7 in diabetic nephropathy.
Wang HJ, Liu H, Lin YH, Zhang SJ
Human & experimental toxicology 2021 Apr;40(4):587-595
Human & experimental toxicology 2021 Apr;40(4):587-595
Cartilage endplate stem cells inhibit intervertebral disc degeneration by releasing exosomes to nucleus pulposus cells to activate Akt/autophagy.
Luo L, Jian X, Sun H, Qin J, Wang Y, Zhang J, Shen Z, Yang D, Li C, Zhao P, Liu M, Tian Z, Zhou Y
Stem cells (Dayton, Ohio) 2021 Apr;39(4):467-481
Stem cells (Dayton, Ohio) 2021 Apr;39(4):467-481
LRP6 downregulation promotes cardiomyocyte proliferation and heart regeneration.
Wu Y, Zhou L, Liu H, Duan R, Zhou H, Zhang F, He X, Lu D, Xiong K, Xiong M, Zhuang J, Liu Y, Li L, Liang D, Chen YH
Cell research 2021 Apr;31(4):450-462
Cell research 2021 Apr;31(4):450-462
A chemical genetics approach to examine the functions of AAA proteins.
Cupido T, Jones NH, Grasso MJ, Pisa R, Kapoor TM
Nature structural & molecular biology 2021 Apr;28(4):388-397
Nature structural & molecular biology 2021 Apr;28(4):388-397
Programmed cell death 4 modulates lysosomal function by inhibiting TFEB translation.
Chen X, Guan Y, Zhang Y, Jia Y, Li W, Guo C, Li Y, Wang X, Shi Y, Wang Q, Zhu F, Li Y, Zhang L
Cell death and differentiation 2021 Apr;28(4):1237-1250
Cell death and differentiation 2021 Apr;28(4):1237-1250
Small molecule screening identified cepharanthine as an inhibitor of porcine reproductive and respiratory syndrome virus infection in vitro by suppressing integrins/ILK/RACK1/PKCα/NF-κB signalling axis.
Yang C, Zuo Q, Liu X, Zhao Q, Pu H, Gao L, Zhao L, Guo Z, Lin Y, Liu J, Bi J, Yin G
Veterinary microbiology 2021 Apr;255:109016
Veterinary microbiology 2021 Apr;255:109016
Characterization of an endoplasmic reticulum stress-related signature to evaluate immune features and predict prognosis in glioma.
Zhang Q, Guan G, Cheng P, Cheng W, Yang L, Wu A
Journal of cellular and molecular medicine 2021 Apr;25(8):3870-3884
Journal of cellular and molecular medicine 2021 Apr;25(8):3870-3884
ARID1B/SUB1-activated lncRNA HOXA-AS2 drives the malignant behaviour of hepatoblastoma through regulation of HOXA3.
Liu G, Liu B, Liu X, Xie L, He J, Zhang J, Dong R, Ma D, Dong K, Ye M
Journal of cellular and molecular medicine 2021 Apr;25(7):3524-3536
Journal of cellular and molecular medicine 2021 Apr;25(7):3524-3536
Helicobacter pylori inhibits autophagic flux and promotes its intracellular survival and colonization by down-regulating SIRT1.
Wang X, Wang B, Gao W, An Y, Dong G, Jia J, Yang Q
Journal of cellular and molecular medicine 2021 Apr;25(7):3348-3360
Journal of cellular and molecular medicine 2021 Apr;25(7):3348-3360
Glucagon-like peptide 2 attenuates intestinal mucosal barrier injury through the MLCK/pMLC signaling pathway in a piglet model.
Chang Y, Deng Q, Zhang Z, Zhao H, Tang J, Chen X, Liu G, Tian G, Cai J, Jia G
Journal of cellular physiology 2021 Apr;236(4):3015-3032
Journal of cellular physiology 2021 Apr;236(4):3015-3032
Ten-m/Odz3 regulates migration and differentiation of chondrogenic ATDC5 cells via RhoA-mediated actin reorganization.
Takano I, Takeshita N, Yoshida M, Seki D, Oyanagi T, Kimura S, Jiang W, Sasaki K, Sogi C, Kawatsu M, Takano-Yamamoto T
Journal of cellular physiology 2021 Apr;236(4):2906-2919
Journal of cellular physiology 2021 Apr;236(4):2906-2919
Involvement of oxidative stress-induced annulus fibrosus cell and nucleus pulposus cell ferroptosis in intervertebral disc degeneration pathogenesis.
Yang RZ, Xu WN, Zheng HL, Zheng XF, Li B, Jiang LS, Jiang SD
Journal of cellular physiology 2021 Apr;236(4):2725-2739
Journal of cellular physiology 2021 Apr;236(4):2725-2739
Novel role of CXCL14 in modulating STAR expression in luteinized granulosa cells: implication for progesterone synthesis in PCOS patients.
Qi J, Li J, Wang Y, Wang W, Zhu Q, He Y, Lu Y, Wu H, Li X, Zhu Z, Ding Y, Xu R, Sun Y
Translational research : the journal of laboratory and clinical medicine 2021 Apr;230:55-67
Translational research : the journal of laboratory and clinical medicine 2021 Apr;230:55-67
Melatonin exerts protective effects on diabetic retinopathy via inhibition of Wnt/β-catenin pathway as revealed by quantitative proteomics.
Yan M, Wang H, Gu Y, Li X, Tao L, Lu P
Experimental eye research 2021 Apr;205:108521
Experimental eye research 2021 Apr;205:108521
Depression-like behavior is associated with lower Per2 mRNA expression in the lateral habenula of rats.
Li Y, Li G, Li J, Cai X, Sun Y, Zhang B, Zhao H
Genes, brain, and behavior 2021 Apr;20(4):e12702
Genes, brain, and behavior 2021 Apr;20(4):e12702
MNK as a potential pharmacological target for suppressing LPS-induced acute lung injury in mice.
Gao J, Teng L, Yang S, Huang S, Li L, Zhou L, Liu G, Tang H
Biochemical pharmacology 2021 Apr;186:114499
Biochemical pharmacology 2021 Apr;186:114499
Harmine alleviates atherogenesis by inhibiting disturbed flow-mediated endothelial activation via protein tyrosine phosphatase PTPN14 and YAP.
Yang Y, Ma Q, Li Z, Wang H, Zhang C, Liu Y, Li B, Wang Y, Cui Q, Xue F, Ai D, Zhu Y, He J
British journal of pharmacology 2021 Apr;178(7):1524-1540
British journal of pharmacology 2021 Apr;178(7):1524-1540
A novel amphibian-derived peptide alleviated ultraviolet B-induced photodamage in mice.
Zhang X, Feng C, Wang S, Wang Y, Fu Z, Zhang Y, Sun H, Xie C, Fu Y, Tao J, Luo M, Yang X
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Apr;136:111258
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Apr;136:111258
Effects of miR-132-3p on progress and epithelial mesenchymal transition of non-small cell lung cancer via regulating KLF7.
Wang N, Xu Y, Guo Q, Zhu C, Zhao W, Qian W, Zheng M
Journal of thoracic disease 2021 Apr;13(4):2426-2436
Journal of thoracic disease 2021 Apr;13(4):2426-2436
POST1/C12ORF49 regulates the SREBP pathway by promoting site-1 protease maturation.
Xiao J, Xiong Y, Yang LT, Wang JQ, Zhou ZM, Dong LW, Shi XJ, Zhao X, Luo J, Song BL
Protein & cell 2021 Apr;12(4):279-296
Protein & cell 2021 Apr;12(4):279-296
Transcription factor EB promotes rheumatoid arthritis of Sprague-Dawley rats via regulating autophagy.
Xu L, Pan J
3 Biotech 2021 Apr;11(4):162
3 Biotech 2021 Apr;11(4):162
DBA/1 mice display equivalent cardiac function to C57BL/6J mice.
Wang Z, Zhou Z, Guo P, Wang M, Sun H, Tai Y, Xiao F, Han Y, Wei W, Wang Q
Experimental physiology 2021 Apr;106(4):868-881
Experimental physiology 2021 Apr;106(4):868-881
A partial loss-of-function variant in GNRNR gene in a Chinese cohort with idiopathic hypogonadotropic hypogonadism.
Chen Y, Sun T, Niu Y, Wang D, Liu K, Wang T, Wang S, Xu H, Liu J
Translational andrology and urology 2021 Apr;10(4):1676-1687
Translational andrology and urology 2021 Apr;10(4):1676-1687
PolyQ-expanded proteins impair cellular proteostasis of ataxin-3 through sequestering the co-chaperone HSJ1 into aggregates.
Yue HW, Hong JY, Zhang SX, Jiang LL, Hu HY
Scientific reports 2021 Apr 9;11(1):7815
Scientific reports 2021 Apr 9;11(1):7815
ATP6V0A1 encoding the a1-subunit of the V0 domain of vacuolar H+-ATPases is essential for brain development in humans and mice.
Aoto K, Kato M, Akita T, Nakashima M, Mutoh H, Akasaka N, Tohyama J, Nomura Y, Hoshino K, Ago Y, Tanaka R, Epstein O, Ben-Haim R, Heyman E, Miyazaki T, Belal H, Takabayashi S, Ohba C, Takata A, Mizuguchi T, Miyatake S, Miyake N, Fukuda A, Matsumoto N, Saitsu H
Nature communications 2021 Apr 8;12(1):2107
Nature communications 2021 Apr 8;12(1):2107
Therapeutic Effect of Endothelin-Converting Enzyme Inhibitor on Chronic Kidney Disease through the Inhibition of Endoplasmic Reticulum Stress and the NLRP3 Inflammasome.
Hsu YH, Zheng CM, Chou CL, Chen YJ, Lee YH, Lin YF, Chiu HW
Biomedicines 2021 Apr 7;9(4)
Biomedicines 2021 Apr 7;9(4)
Fangchinoline suppresses conjunctival melanoma by directly binding FUBP2 and inhibiting the homologous recombination pathway.
Bao K, Li Y, Wei J, Li R, Yang J, Shi J, Li B, Zhu J, Mao F, Jia R, Li J
Cell death & disease 2021 Apr 7;12(4):380
Cell death & disease 2021 Apr 7;12(4):380
DOCK7 protects against replication stress by promoting RPA stability on chromatin.
Gao M, Guo G, Huang J, Hou X, Ham H, Kim W, Zhao F, Tu X, Zhou Q, Zhang C, Zhu Q, Liu J, Yan Y, Xu Z, Yin P, Luo K, Weroha J, Deng M, Billadeau DD, Lou Z
Nucleic acids research 2021 Apr 6;49(6):3322-3337
Nucleic acids research 2021 Apr 6;49(6):3322-3337
MCPIP1-mediated NFIC alternative splicing inhibits proliferation of triple-negative breast cancer via cyclin D1-Rb-E2F1 axis.
Chen F, Wang Q, Yu X, Yang N, Wang Y, Zeng Y, Zheng Z, Zhou F, Zhou Y
Cell death & disease 2021 Apr 6;12(4):370
Cell death & disease 2021 Apr 6;12(4):370
Regulation of MRP4 Expression by circHIPK3 via Sponging miR-124-3p/miR-4524-5p in Hepatocellular Carcinoma.
Hu H, Wang Y, Qin Z, Sun W, Chen Y, Wang J, Wang Y, Nie J, Chen L, Cai S, Yu L, Zeng S
Biomedicines 2021 Apr 30;9(5)
Biomedicines 2021 Apr 30;9(5)
ARID3A promotes the development of colorectal cancer by upregulating AURKA.
Tang J, Yang L, Li Y, Ning X, Chaulagain A, Wang T, Wang D
Carcinogenesis 2021 Apr 30;42(4):578-586
Carcinogenesis 2021 Apr 30;42(4):578-586
Anti-tumor activity of a novel proteasome inhibitor D395 against multiple myeloma and its lower cardiotoxicity compared with carfilzomib.
Shen X, Wu C, Lei M, Yan Q, Zhang H, Zhang L, Wang X, Yang Y, Li J, Zhu Y, Chen L
Cell death & disease 2021 Apr 30;12(5):429
Cell death & disease 2021 Apr 30;12(5):429
The role of E26 transformation-specific variant transcription factor 5 in colorectal cancer cell proliferation and cell cycle progression.
Peng Y, Feng H, Wang C, Song Z, Zhang Y, Liu K, Cheng X, Zhao R
Cell death & disease 2021 Apr 30;12(5):427
Cell death & disease 2021 Apr 30;12(5):427
TRIM25 activates AKT/mTOR by inhibiting PTEN via K63-linked polyubiquitination in non-small cell lung cancer.
He YM, Zhou XM, Jiang SY, Zhang ZB, Cao BY, Liu JB, Zeng YY, Zhao J, Mao XL
Acta pharmacologica Sinica 2021 Apr 30;
Acta pharmacologica Sinica 2021 Apr 30;
Interleukin-17A mediates tobacco smoke-induced lung cancer epithelial-mesenchymal transition through transcriptional regulation of ΔNp63α on miR-19.
Xie C, Zhu J, Huang C, Yang X, Wang X, Meng Y, Geng S, Wu J, Shen H, Hu Z, Meng Z, Li X, Zhong C
Cell biology and toxicology 2021 Apr 3;
Cell biology and toxicology 2021 Apr 3;
Multi-omics analysis to identify susceptibility genes for colorectal cancer.
Yuan Y, Bao J, Chen Z, Villanueva AD, Wen W, Wang F, Zhao D, Fu X, Cai Q, Long J, Shu XO, Zheng D, Moreno V, Zheng W, Lin W, Guo X
Human molecular genetics 2021 Apr 27;30(5):321-330
Human molecular genetics 2021 Apr 27;30(5):321-330
Knockdown of the Ribosomal Protein eL38 in HEK293 Cells Changes the Translational Efficiency of Specific Genes.
Gopanenko AV, Kolobova AV, Tupikin AE, Kabilov MR, Malygin AA, Karpova GG
International journal of molecular sciences 2021 Apr 26;22(9)
International journal of molecular sciences 2021 Apr 26;22(9)
Divergent immunometabolic changes in adipose tissue and skeletal muscle with ageing in healthy humans.
Trim WV, Walhin JP, Koumanov F, Bouloumié A, Lindsay MA, Chen YC, Travers RL, Turner JE, Thompson D
The Journal of physiology 2021 Apr 24;
The Journal of physiology 2021 Apr 24;
ZIP8 mediates the extracellular matrix degradation of nucleus pulposus cells via NF-κB signaling pathway.
Ding W, Ge Y, Sun H, Xu J, Gu H, Bian C, Chen H, Jiang L, Yin X
Biochemical and biophysical research communications 2021 Apr 23;550:30-36
Biochemical and biophysical research communications 2021 Apr 23;550:30-36
Abelson interactor 1 splice isoform-L plays an anti-oncogenic role in colorectal carcinoma through interactions with WAVE2 and full-length Abelson interactor 1.
Li K, Peng YF, Guo JZ, Li M, Zhang Y, Chen JY, Lin TR, Yu X, Yu WD
World journal of gastroenterology 2021 Apr 21;27(15):1595-1615
World journal of gastroenterology 2021 Apr 21;27(15):1595-1615
Impaired 26S Proteasome Assembly Precedes Neuronal Loss in Mutant UBQLN2 Rats.
Zhang W, Huang B, Gao L, Huang C
International journal of molecular sciences 2021 Apr 21;22(9)
International journal of molecular sciences 2021 Apr 21;22(9)
Generation of a Polyclonal Antibody against the Mouse Metal Transporter ZIP8.
Wei G, Wu Y, Zhao N
Antibodies (Basel, Switzerland) 2021 Apr 21;10(2)
Antibodies (Basel, Switzerland) 2021 Apr 21;10(2)
Inhibition of Notch1 signaling reduces hepatocyte injury in nonalcoholic fatty liver disease via autophagy.
Zhang M, Wu P, Li M, Guo Y, Tian T, Liao X, Tan S
Biochemical and biophysical research communications 2021 Apr 2;547:131-138
Biochemical and biophysical research communications 2021 Apr 2;547:131-138
Role of Small Envelope Protein in Sustaining the Intracellular and Extracellular Levels of Hepatitis B Virus Large and Middle Envelope Proteins.
Zhang J, Wang Y, Fu S, Yuan Q, Wang Q, Xia N, Wen Y, Li J, Tong S
Viruses 2021 Apr 2;13(4)
Viruses 2021 Apr 2;13(4)
Ubiquitin-specific peptidase 39 promotes human glioma cells migration and invasion by facilitating ADAM9 mRNA maturation.
Xiao Y, Ma W, Hu W, Di Q, Zhao X, Ma X, Chen X, Sun P, Wu H, Wu Z, Chen W
Molecular oncology 2021 Apr 2;
Molecular oncology 2021 Apr 2;
CircLIFR synergizes with MSH2 to attenuate chemoresistance via MutSα/ATM-p73 axis in bladder cancer.
Zhang H, Xiao X, Wei W, Huang C, Wang M, Wang L, He Y, Sun J, Jiang Y, Jiang G, Zhang X
Molecular cancer 2021 Apr 19;20(1):70
Molecular cancer 2021 Apr 19;20(1):70
RUNX1 promotes MAPK signaling to increase tumor progression and metastasis via OPN in head and neck cancer.
Liu K, Hu H, Jiang H, Zhang H, Gong S, Wei D, Yu Z
Carcinogenesis 2021 Apr 17;42(3):414-422
Carcinogenesis 2021 Apr 17;42(3):414-422
miR-324-3p reverses cisplatin resistance by inducing GPX4-mediated ferroptosis in lung adenocarcinoma cell line A549.
Deng SH, Wu DM, Li L, Liu T, Zhang T, Li J, Yu Y, He M, Zhao YY, Han R, Xu Y
Biochemical and biophysical research communications 2021 Apr 16;549:54-60
Biochemical and biophysical research communications 2021 Apr 16;549:54-60
Crystal structures reveal a novel dimer of the RWD domain of human general control nonderepressible 2.
Hei Z, Wu S, Zheng L, Zhou J, Liu Z, Wang J, Fang P
Biochemical and biophysical research communications 2021 Apr 16;549:164-170
Biochemical and biophysical research communications 2021 Apr 16;549:164-170
Promyelocytic leukemia protein promotes the phenotypic switch of smooth muscle cells in atherosclerotic plaques of human coronary arteries.
Karle W, Becker S, Stenzel P, Knosalla C, Siegel G, Baum O, Zakrzewicz A, Berkholz J
Clinical science (London, England : 1979) 2021 Apr 16;135(7):887-905
Clinical science (London, England : 1979) 2021 Apr 16;135(7):887-905
Effects of CMYA1 overexpression on cardiac structure and function in mice.
Li C, Zhang H, Xie Y, Liu S, Zhao R, Huang J, Huang J, Wei Y
Acta biochimica et biophysica Sinica 2021 Apr 15;53(5):593-600
Acta biochimica et biophysica Sinica 2021 Apr 15;53(5):593-600
Dual effects of fibrinogen decoration on the tuning of silica nanoparticles-induced autophagic response: The implication of sedimentation and internalization.
Zhang L, Wei W, Liu Z, Liu X, Song E, Song Y
Journal of hazardous materials 2021 Apr 15;408:124467
Journal of hazardous materials 2021 Apr 15;408:124467
Chemoproteomics-enabled discovery of covalent RNF114-based degraders that mimic natural product function.
Luo M, Spradlin JN, Boike L, Tong B, Brittain SM, McKenna JM, Tallarico JA, Schirle M, Maimone TJ, Nomura DK
Cell chemical biology 2021 Apr 15;28(4):559-566.e15
Cell chemical biology 2021 Apr 15;28(4):559-566.e15
Glaucocalyxin A induces cell cycle arrest and apoptosis via inhibiting NF-κB/p65 signaling pathway in melanoma cells.
Chen J, Zhang W, Pan C, Fan J, Zhong X, Tang S
Life sciences 2021 Apr 15;271:119185
Life sciences 2021 Apr 15;271:119185
Synthesis, characterization, and targeted chemotherapy of SCT200-linker-monomethyl auristatin E conjugates.
Hu X, Jiang H, Bai W, Liu X, Miao Q, Wang L, Jin J, Cui A, Liu R, Li Z
European journal of medicinal chemistry 2021 Apr 15;216:113297
European journal of medicinal chemistry 2021 Apr 15;216:113297
The biological function and clinical significance of STIL in osteosarcoma.
Ji SF, Wen SL, Sun Y, Huang PW, Wu H, He ML
Cancer cell international 2021 Apr 15;21(1):218
Cancer cell international 2021 Apr 15;21(1):218
Loss of Mitochondrial Protease CLPP Activates Type I IFN Responses through the Mitochondrial DNA-cGAS-STING Signaling Axis.
Torres-Odio S, Lei Y, Gispert S, Maletzko A, Key J, Menissy SS, Wittig I, Auburger G, West AP
Journal of immunology (Baltimore, Md. : 1950) 2021 Apr 15;206(8):1890-1900
Journal of immunology (Baltimore, Md. : 1950) 2021 Apr 15;206(8):1890-1900
AKR1B10 negatively regulates autophagy through reducing GAPDH upon glucose starvation in colon cancer.
Li W, Liu C, Huang Z, Shi L, Zhong C, Zhou W, Meng P, Li Z, Wang S, Luo F, Yan J, Wu T
Journal of cell science 2021 Apr 15;134(8)
Journal of cell science 2021 Apr 15;134(8)
KLF7/VPS35 axis contributes to hepatocellular carcinoma progression through CCDC85C-activated β-catenin pathway.
Guo Y, Chai B, Jia J, Yang M, Li Y, Zhang R, Wang S, Xu J
Cell & bioscience 2021 Apr 15;11(1):73
Cell & bioscience 2021 Apr 15;11(1):73
Cytoplasmic DNA sensing by KU complex in aged CD4+ T cell potentiates T cell activation and aging-related autoimmune inflammation.
Wang Y, Fu Z, Li X, Liang Y, Pei S, Hao S, Zhu Q, Yu T, Pei Y, Yuan J, Ye J, Fu J, Xu J, Hong J, Yang R, Hou H, Huang X, Peng C, Zheng M, Xiao Y
Immunity 2021 Apr 13;54(4):632-647.e9
Immunity 2021 Apr 13;54(4):632-647.e9
TDP-43 prevents endogenous RNAs from triggering a lethal RIG-I-dependent interferon response.
Dunker W, Ye X, Zhao Y, Liu L, Richardson A, Karijolich J
Cell reports 2021 Apr 13;35(2):108976
Cell reports 2021 Apr 13;35(2):108976
Changes in hepatic triglyceride content with the activation of ER stress and increased FGF21 secretion during pregnancy.
Lu J, Gong Y, Wei X, Yao Z, Yang R, Xin J, Gao L, Shao S
Nutrition & metabolism 2021 Apr 13;18(1):40
Nutrition & metabolism 2021 Apr 13;18(1):40
EpCAM promotes endosomal modulation of the cortical RhoA zone for epithelial organization.
Gaston C, De Beco S, Doss B, Pan M, Gauquelin E, D'Alessandro J, Lim CT, Ladoux B, Delacour D
Nature communications 2021 Apr 13;12(1):2226
Nature communications 2021 Apr 13;12(1):2226
Inflammatory Injury and Mitophagy in the Cock Heart Induced by the Oral Administration of Hexavalent Chromium.
Wang Y, Wang L, Wang X, Cheng G, Xing Y, Zhang M, Zhang P, Liu J
Biological trace element research 2021 Apr 13;
Biological trace element research 2021 Apr 13;
TRIM39 deficiency inhibits tumor progression and autophagic flux in colorectal cancer via suppressing the activity of Rab7.
Hu J, Ding X, Tian S, Chu Y, Liu Z, Li Y, Li X, Wang G, Wang L, Wang Z
Cell death & disease 2021 Apr 12;12(4):391
Cell death & disease 2021 Apr 12;12(4):391
Reciprocal regulation of RIG-I and XRCC4 connects DNA repair with RIG-I immune signaling.
Guo G, Gao M, Gao X, Zhu B, Huang J, Tu X, Kim W, Zhao F, Zhou Q, Zhu S, Wu Z, Yan Y, Zhang Y, Zeng X, Zhu Q, Yin P, Luo K, Sun J, Deng M, Lou Z
Nature communications 2021 Apr 12;12(1):2187
Nature communications 2021 Apr 12;12(1):2187
ADAMTS19 Suppresses Cell Migration and Invasion by Targeting S100A16 via the NF-κB Pathway in Human Gastric Cancer.
Jiang Y, Yu X, Zhao Y, Huang J, Li T, Chen H, Zhou J, Huang Z, Yang Z
Biomolecules 2021 Apr 12;11(4)
Biomolecules 2021 Apr 12;11(4)
NET1 promotes HCC growth and metastasis in vitro and in vivo via activating the Akt signaling pathway.
Chen ZH, Ni QZ, Zhang XP, Ma N, Feng JK, Wang K, Li JJ, Xie D, Ma XY, Cheng SQ
Aging 2021 Apr 11;13(7):10672-10687
Aging 2021 Apr 11;13(7):10672-10687
p53-targeted lncRNA ST7-AS1 acts as a tumour suppressor by interacting with PTBP1 to suppress the Wnt/β-catenin signalling pathway in glioma.
Sheng J, He X, Yu W, Chen Y, Long Y, Wang K, Zhu S, Liu Q
Cancer letters 2021 Apr 10;503:54-68
Cancer letters 2021 Apr 10;503:54-68
Dcaf11 activates Zscan4-mediated alternative telomere lengthening in early embryos and embryonic stem cells.
Le R, Huang Y, Zhang Y, Wang H, Lin J, Dong Y, Li Z, Guo M, Kou X, Zhao Y, Chen M, Zhu Q, Zhao A, Yin J, Sun J, Su Z, Shi K, Gao Y, Chen J, Liu W, Kang L, Wang Y, Li C, Liu X, Gao R, Wang H, Ju Z, Gao S
Cell stem cell 2021 Apr 1;28(4):732-747.e9
Cell stem cell 2021 Apr 1;28(4):732-747.e9
Polychlorinated biphenyl quinone regulates MLKL phosphorylation that stimulates exosome biogenesis and secretion via a short negative feedback loop.
Peng L, Wang Y, Yang B, Qin Q, Song E, Song Y
Environmental pollution (Barking, Essex : 1987) 2021 Apr 1;274:115606
Environmental pollution (Barking, Essex : 1987) 2021 Apr 1;274:115606
Design and screening of a novel neuropilin-1 targeted penetrating peptide for anti-angiogenic therapy in glioma.
Zhao L, Chen H, Lu L, Zhao C, Malichewe CV, Wang L, Guo X, Zhang X
Life sciences 2021 Apr 1;270:119113
Life sciences 2021 Apr 1;270:119113
MicroRNA-376b-5p targets SOX7 to alleviate ischemic brain injury in a mouse model through activating Wnt/β-catenin signaling pathway.
Zhao B, Wang P, Yu J, Zhang Y
Life sciences 2021 Apr 1;270:119072
Life sciences 2021 Apr 1;270:119072
RANK promotes colorectal cancer migration and invasion by activating the Ca2+-calcineurin/NFATC1-ACP5 axis.
Liang Q, Wang Y, Lu Y, Zhu Q, Xie W, Tang N, Huang L, An T, Zhang D, Yan A, Liu S, Ye L, Zhu C
Cell death & disease 2021 Apr 1;12(4):336
Cell death & disease 2021 Apr 1;12(4):336
Identification of Beilschmiedia tsangii Root Extract as a Liver Cancer Cell-Normal Keratinocyte Dual-Selective NRF2 Regulator.
Chen YS, Chang HS, Hsiao HH, Chen YF, Kuo YP, Yen FL, Yen CH
Antioxidants (Basel, Switzerland) 2021 Apr 1;10(4)
Antioxidants (Basel, Switzerland) 2021 Apr 1;10(4)
Lycopene alleviates oxidative stress via the PI3K/Akt/Nrf2pathway in a cell model of Alzheimer's disease.
Fang Y, Ou S, Wu T, Zhou L, Tang H, Jiang M, Xu J, Guo K
PeerJ 2020;8:e9308
PeerJ 2020;8:e9308
Conditioned medium from M2b macrophages modulates the proliferation, migration, and apoptosis of pulmonary artery smooth muscle cells by deregulating the PI3K/Akt/FoxO3a pathway.
Huang S, Yue Y, Feng K, Huang X, Li H, Hou J, Yang S, Huang S, Liang M, Chen G, Wu Z
PeerJ 2020;8:e9110
PeerJ 2020;8:e9110
Icariin protects against sodium azide-induced neurotoxicity by activating the PI3K/Akt/GSK-3β signaling pathway.
Zhang Y, Huang N, Lu H, Huang J, Jin H, Shi J, Jin F
PeerJ 2020;8:e8955
PeerJ 2020;8:e8955
Glycyrrhizin suppresses epithelial-mesenchymal transition by inhibiting high-mobility group box1 via the TGF-β1/Smad2/3 pathway in lung epithelial cells.
Gui Y, Sun J, You W, Wei Y, Tian H, Jiang S
PeerJ 2020;8:e8514
PeerJ 2020;8:e8514
miR-29a-3p directly targets Smad nuclear interacting protein 1 and inhibits the migration and proliferation of cervical cancer HeLa cells.
Chen Y, Zhang W, Yan L, Zheng P, Li J
PeerJ 2020;8:e10148
PeerJ 2020;8:e10148
Examination of the Effect of a 50-Hz Electromagnetic Field at 500 μT on Parameters Related With the Cardiovascular System in Rats.
Zhang Y, Li L, Liu X, Ding L, Wu X, Wang J, He M, Hou H, Ruan G, Lai J, Chen C
Frontiers in public health 2020;8:87
Frontiers in public health 2020;8:87
Mimicking the Organic and Inorganic Composition of Anabolic Bone Enhances Human Mesenchymal Stem Cell Osteoinduction and Scaffold Mechanical Properties.
Mondragón E, Cowdin M, Taraballi F, Minardi S, Tasciotti E, Gregory CA, Kaunas R
Frontiers in bioengineering and biotechnology 2020;8:753
Frontiers in bioengineering and biotechnology 2020;8:753
Histone Deacetylases Inhibit the Snail2-Mediated EMT During Metastasis of Hepatocellular Carcinoma Cells.
Hu Y, Nie Q, Dai M, Chen F, Wu H
Frontiers in cell and developmental biology 2020;8:752
Frontiers in cell and developmental biology 2020;8:752
RNA-Binding Protein HuR Suppresses Inflammation and Promotes Extracellular Matrix Homeostasis via NKRF in Intervertebral Disc Degeneration.
Shao Z, Tu Z, Shi Y, Li S, Wu A, Wu Y, Tian N, Sun L, Pan Z, Chen L, Gao W, Zhou Y, Wang X, Zhang X
Frontiers in cell and developmental biology 2020;8:611234
Frontiers in cell and developmental biology 2020;8:611234
Knockdown of POSTN Inhibits Osteogenic Differentiation of Mesenchymal Stem Cells From Patients With Steroid-Induced Osteonecrosis.
Han L, Gong S, Wang R, Liu S, Wang B, Chen G, Gong T, Xu W
Frontiers in cell and developmental biology 2020;8:606289
Frontiers in cell and developmental biology 2020;8:606289
Caspase-8 Inhibition Prevents the Cleavage and Degradation of E3 Ligase Substrate Receptor Cereblon and Potentiates Its Biological Function.
Zhou L, Yu W, Jayabalan DS, Niesvizky R, Jaffrey SR, Huang X, Xu G
Frontiers in cell and developmental biology 2020;8:605989
Frontiers in cell and developmental biology 2020;8:605989
HDAC6 Regulates the Fusion of Autophagosome and Lysosome to Involve in Odontoblast Differentiation.
Zhan Y, Wang H, Zhang L, Pei F, Chen Z
Frontiers in cell and developmental biology 2020;8:605609
Frontiers in cell and developmental biology 2020;8:605609
Transient Receptor Potential Channel 6 Knockout Ameliorates Kidney Fibrosis by Inhibition of Epithelial-Mesenchymal Transition.
Zhang Y, Yin N, Sun A, Wu Q, Hu W, Hou X, Zeng X, Zhu M, Liao Y
Frontiers in cell and developmental biology 2020;8:602703
Frontiers in cell and developmental biology 2020;8:602703
Iron Overload Is Associated With Accelerated Progression of Osteoarthritis: The Role of DMT1 Mediated Iron Homeostasis.
Jing X, Lin J, Du T, Jiang Z, Li T, Wang G, Liu X, Cui X, Sun K
Frontiers in cell and developmental biology 2020;8:594509
Frontiers in cell and developmental biology 2020;8:594509
miR-766-3p Targeting BCL9L Suppressed Tumorigenesis, Epithelial-Mesenchymal Transition, and Metastasis Through the β-Catenin Signaling Pathway in Osteosarcoma Cells.
Zhang S, Chen H, Liu W, Fang L, Qian Z, Kong R, Zhang Q, Li J, Cao X
Frontiers in cell and developmental biology 2020;8:594135
Frontiers in cell and developmental biology 2020;8:594135
Deficiency of LMP10 Attenuates Diet-Induced Atherosclerosis by Inhibiting Macrophage Polarization and Inflammation in Apolipoprotein E Deficient Mice.
Liao J, An X, Yang X, Lin QY, Liu S, Xie Y, Bai J, Xia YL, Li HH
Frontiers in cell and developmental biology 2020;8:592048
Frontiers in cell and developmental biology 2020;8:592048
p.His16Arg of STXBP1 (MUNC18-1) Associated With Syntaxin 3B Causes Autosomal Dominant Congenital Nystagmus.
Li Y, Jiang L, Wang L, Wang C, Liu C, Guo A, Liu M, Zhang L, Ma C, Zhang X, Gao S, Liu JY
Frontiers in cell and developmental biology 2020;8:591781
Frontiers in cell and developmental biology 2020;8:591781
EZH2-Inhibited MicroRNA-454-3p Promotes M2 Macrophage Polarization in Glioma.
Qi B, Yang C, Zhu Z, Chen H
Frontiers in cell and developmental biology 2020;8:574940
Frontiers in cell and developmental biology 2020;8:574940
Modulation of Increased mGluR1 Signaling by RGS8 Protects Purkinje Cells From Dendritic Reduction and Could Be a Common Mechanism in Diverse Forms of Spinocerebellar Ataxia.
Wu QW, Kapfhammer JP
Frontiers in cell and developmental biology 2020;8:569889
Frontiers in cell and developmental biology 2020;8:569889
MicroRNA-221/222 Mediates ADSC-Exosome-Induced Cardioprotection Against Ischemia/Reperfusion by Targeting PUMA and ETS-1.
Lai TC, Lee TL, Chang YC, Chen YC, Lin SR, Lin SW, Pu CM, Tsai JS, Chen YL
Frontiers in cell and developmental biology 2020;8:569150
Frontiers in cell and developmental biology 2020;8:569150
Glycogen Phosphorylase B Is Regulated by miR101-3p and Promotes Hepatocellular Carcinoma Tumorigenesis.
Cui G, Wang H, Liu W, Xing J, Song W, Zeng Z, Liu L, Wang H, Wang X, Luo H, Leng X, Shen S
Frontiers in cell and developmental biology 2020;8:566494
Frontiers in cell and developmental biology 2020;8:566494
Oct4 Regulates the Transition of Cancer Stem-Like Cells to Tumor Endothelial-Like Cells in Human Liver Cancer.
Liu HL, Tang HT, Yang HL, Deng TT, Xu YP, Xu SQ, Peng L, Wang Z, Fang Q, Kuang XY, Li QS
Frontiers in cell and developmental biology 2020;8:563316
Frontiers in cell and developmental biology 2020;8:563316
Overexpression of FAM46A, a Non-canonical Poly(A) Polymerase, Promotes Hemin-Induced Hemoglobinization in K562 Cells.
Lin HH, Lo YL, Wang WC, Huang KY, I KY, Chang GW
Frontiers in cell and developmental biology 2020;8:414
Frontiers in cell and developmental biology 2020;8:414
Siwei Jianbu decoction improves painful paclitaxel-induced peripheral neuropathy in mouse model by modulating the NF-κB and MAPK signaling pathways.
Suo J, Wang M, Zhang P, Lu Y, Xu R, Zhang L, Qiu S, Zhang Q, Qian Y, Meng J, Zhu J
Regenerative medicine research 2020;8:2
Regenerative medicine research 2020;8:2
The Changes of Twist1 Pathway in Pulmonary Microvascular Permeability in a Newborn Rat Model of Hyperoxia-Induced Acute Lung Injury.
Ruan Y, Dong W, Kang L, Lei X, Zhang R, Wang F, Zhu X
Frontiers in pediatrics 2020;8:190
Frontiers in pediatrics 2020;8:190
CDKN2a/p16 Antagonizes Hepatic Stellate Cell Activation and Liver Fibrosis by Modulating ROS Levels.
Lv F, Li N, Kong M, Wu J, Fan Z, Miao D, Xu Y, Ye Q, Wang Y
Frontiers in cell and developmental biology 2020;8:176
Frontiers in cell and developmental biology 2020;8:176
Crx Is Posttranscriptionally Regulated by Light Stimulation in Postnatal Rat Retina.
Wu Y, Qiu J, Chen S, Chen X, Zhang J, Zhuang J, Liu S, Yang M, Zhou P, Chen H, Ge J, Yu K, Zhuang J
Frontiers in cell and developmental biology 2020;8:174
Frontiers in cell and developmental biology 2020;8:174
S-Adenosylmethionine Alleviates Amyloid-β-Induced Neural Injury by Enhancing Trans-Sulfuration Pathway Activity in Astrocytes.
Wan X, Ma B, Wang X, Guo C, Sun J, Cui J, Li L
Journal of Alzheimer's disease : JAD 2020;76(3):981-995
Journal of Alzheimer's disease : JAD 2020;76(3):981-995
Dendrobium nobile Lindl. Alkaloids Ameliorate Cognitive Dysfunction in Senescence Accelerated SAMP8 Mice by Decreasing Amyloid-β Aggregation and Enhancing Autophagy Activity.
Lv LL, Liu B, Liu J, Li LS, Jin F, Xu YY, Wu Q, Liu J, Shi JS
Journal of Alzheimer's disease : JAD 2020;76(2):657-669
Journal of Alzheimer's disease : JAD 2020;76(2):657-669
Oxytocin Alleviates MPTP-Induced Neurotoxicity in Mice by Targeting MicroRNA-26a/Death-Associated Protein Kinase 1 Pathway.
Almansoub HAMM, Tang H, Wu Y, Wang DQ, Mahaman YAR, Salissou MTM, Lu Y, Hu F, Zhou LT, Almansob YAM, Liu D
Journal of Alzheimer's disease : JAD 2020;74(3):883-901
Journal of Alzheimer's disease : JAD 2020;74(3):883-901
miR-193a-3p Mediates Placenta Accreta Spectrum Development by Targeting EFNB2 via Epithelial-Mesenchymal Transition Pathway Under Decidua Defect Conditions.
Li N, Hou R, Yang T, Liu C, Wei J
Frontiers in molecular biosciences 2020;7:613802
Frontiers in molecular biosciences 2020;7:613802
DGCR8/miR-106 Axis Enhances Radiosensitivity of Head and Neck Squamous Cell Carcinomas by Downregulating RUNX3.
Zhang C, Chen H, Deng Z, Long D, Xu L, Liu Z
Frontiers in medicine 2020;7:582097
Frontiers in medicine 2020;7:582097
Identification of Transcriptional Variation in Aortic Remodeling Using a Murine Transverse Aortic Constriction (TAC) Model.
Zhang X, Feng T, Zeng XI, Liang H, Situ B, Zhang Q, Zhou F, Chen Y, Wang T, Cai D, Lin X, Xiu J, Zheng L
Frontiers in cardiovascular medicine 2020;7:581362
Frontiers in cardiovascular medicine 2020;7:581362
Dioscin Protects against Aβ1-42 Oligomers-Induced Neurotoxicity via the Function of SIRT3 and Autophagy.
Zhang Z, Han K, Wang C, Sun C, Jia N
Chemical & pharmaceutical bulletin 2020;68(8):717-725
Chemical & pharmaceutical bulletin 2020;68(8):717-725
Osthole: A Traditional Chinese Medicine for Ocular Anti-Angiogenic Therapy.
Zhang QY, Tao SY, Lu C, Li JJ, Li XM, Jiang Q, Yan B
Ophthalmic research 2020;63(5):483-490
Ophthalmic research 2020;63(5):483-490
Electroacupuncture Improves Motor Symptoms of Parkinson's Disease and Promotes Neuronal Autophagy Activity in Mouse Brain.
Hsu WT, Chen YH, Yang HB, Lin JG, Hung SY
The American journal of Chinese medicine 2020;48(7):1651-1669
The American journal of Chinese medicine 2020;48(7):1651-1669
Overexpression of MECP2 attenuates cigarette smoke extracts induced lung epithelial cell injury by promoting CYP1B1 methylation.
Lin J, Peng J, Liu G, Deng L
The Journal of toxicological sciences 2020;45(3):177-186
The Journal of toxicological sciences 2020;45(3):177-186
TRIB3 promotes hepatocellular carcinoma growth and predicts poor prognosis.
Wang XJ, Li FF, Zhang YJ, Jiang M, Ren WH
Cancer biomarkers : section A of Disease markers 2020;29(3):307-315
Cancer biomarkers : section A of Disease markers 2020;29(3):307-315
BMSC-derived leptin and IGFBP2 promote erlotinib resistance in lung adenocarcinoma cells through IGF-1R activation in hypoxic environment.
Wang F, Zhang L, Sai B, Wang L, Zhang X, Zheng L, Tang J, Li G, Xiang J
Cancer biology & therapy 2020;21(1):61-71
Cancer biology & therapy 2020;21(1):61-71
DLX6-AS1 promotes cell proliferation, migration and EMT of gastric cancer through FUS-regulated MAP4K1.
Wu Q, Ma J, Meng W, Hui P
Cancer biology & therapy 2020;21(1):17-25
Cancer biology & therapy 2020;21(1):17-25
Effect of Wenshen-Yanggan Decoction on Movement Disorder and Substantia Nigra Dopaminergic Neurons in Mice with Chronic Parkinson's Disease.
Tang L, Chen C, Xia B, Wu W, Wei R, Zhu G, Tang J, Zhou X, Liang Y, Zhang ZN, Lu Y, Yang Y, Zhao Y
Evidence-based complementary and alternative medicine : eCAM 2020;2020:9838295
Evidence-based complementary and alternative medicine : eCAM 2020;2020:9838295
Adrenal (Pro)renin Receptor Expression and Serum Soluble (Pro)renin Receptor Concentration in Primary Aldosteronism.
Watanabe D, Morimoto S, Morishima N, Kato Y, Nagashima Y, Shibata N, Ichihara A
International journal of endocrinology 2020;2020:9640103
International journal of endocrinology 2020;2020:9640103
Autophagy Contributes to Host Immunity and Protection against Zika Virus Infection via Type I IFN Signaling.
Huang Y, Wang Y, Meng S, Chen Z, Kong H, Pan T, Lu G, Li X
Mediators of inflammation 2020;2020:9527147
Mediators of inflammation 2020;2020:9527147
Distinct Expression Patterns of Apoptosis and Autophagy-Associated Proteins and Genes during Postnatal Development of Spiral Ganglion Neurons in Rat.
Hou S, Chen P, Chen J, Chen J, Sun L, Chen J, He B, Li Y, Qin H, Hong Y, Li S, He J, Gao D, Mammano F, Yang J
Neural plasticity 2020;2020:9387560
Neural plasticity 2020;2020:9387560
Citron Rho-Interacting Serine/Threonine Kinase Promotes HIF1a-CypA Signaling and Growth of Human Pancreatic Adenocarcinoma.
Cong L, Bai Z, Du Y, Cheng Y
BioMed research international 2020;2020:9210891
BioMed research international 2020;2020:9210891
Electroacupuncture Improved Chronic Cerebral Hypoperfusion-Induced Anxiety-Like Behavior and Memory Impairments in Spontaneously Hypertensive Rats by Downregulating the ACE/Ang II/AT1R Axis and Upregulating the ACE2/Ang-(1-7)/MasR Axis.
Feng P, Wu Z, Liu H, Shen Y, Yao X, Li X, Shen Z
Neural plasticity 2020;2020:9076042
Neural plasticity 2020;2020:9076042
PBX3 Promotes Tumor Growth and Angiogenesis via Activation of AT1R/VEGFR2 Pathway in Papillary Thyroid Carcinoma.
Chen Q, Yu WY, Zhang HH, Zhang SZ, Fang J, Wu F, Ying HZ, Yu CH
BioMed research international 2020;2020:8954513
BioMed research international 2020;2020:8954513
AURKA Increase the Chemosensitivity of Colon Cancer Cells to Oxaliplatin by Inhibiting the TP53-Mediated DNA Damage Response Genes.
Shan B, Zhao R, Zhou J, Zhang M, Qi X, Wang T, Gong J, Wu Y, Zhu Y, Yang W, Zhang Y, Wang G, Li X
BioMed research international 2020;2020:8916729
BioMed research international 2020;2020:8916729
Jian-Pi-Yi-Shen Regulates EPO and Iron Recycling Protein Expressions in Anemic Rats with Chronic Kidney Disease: Accumulation of Hypoxia Inducible Factor-2α via ERK Signaling.
Wang F, Yu H, Huang S, Zheng L, Zheng P, Zhang S, Li S, Chen J
Evidence-based complementary and alternative medicine : eCAM 2020;2020:8894257
Evidence-based complementary and alternative medicine : eCAM 2020;2020:8894257
Exosomes from Bone Marrow Microenvironment-Derived Mesenchymal Stem Cells Affect CML Cells Growth and Promote Drug Resistance to Tyrosine Kinase Inhibitors.
Zhang X, Yang Y, Yang Y, Chen H, Tu H, Li J
Stem cells international 2020;2020:8890201
Stem cells international 2020;2020:8890201
Responsive Expression of MafF to β-Amyloid-Induced Oxidative Stress.
Wang X, Zhang Y, Wan X, Guo C, Cui J, Sun J, Li L
Disease markers 2020;2020:8861358
Disease markers 2020;2020:8861358
EA Ameliorated Depressive Behaviors in CUMS Rats and Was Related to Its Suppressing Autophagy in the Hippocampus.
Zhang Z, Cai X, Yao Z, Wen F, Fu Z, Zhang J, Zhong Z, Huang Y, Qu S
Neural plasticity 2020;2020:8860968
Neural plasticity 2020;2020:8860968
Metformin Reduces the Senescence of Renal Tubular Epithelial Cells in Diabetic Nephropathy via the MBNL1/miR-130a-3p/STAT3 Pathway.
Jiang X, Ruan XL, Xue YX, Yang S, Shi M, Wang LN
Oxidative medicine and cellular longevity 2020;2020:8708236
Oxidative medicine and cellular longevity 2020;2020:8708236
Fuzheng Huayu Recipe Prevented and Treated CCl4-Induced Mice Liver Fibrosis through Regulating Polarization and Chemotaxis of Intrahepatic Macrophages via CCL2 and CX3CL1.
Zhang M, Liu HL, Huang K, Peng Y, Tao YY, Zhao CQ, Hu XD, Liu CH
Evidence-based complementary and alternative medicine : eCAM 2020;2020:8591892
Evidence-based complementary and alternative medicine : eCAM 2020;2020:8591892
Trained Innate Immunity by Repeated Low-Dose Lipopolysaccharide Injections Displays Long-Term Neuroprotective Effects.
Zhou XY, Gao R, Hu J, Gao DP, Liao YL, Yang JJ
Mediators of inflammation 2020;2020:8191079
Mediators of inflammation 2020;2020:8191079
Astaxanthin Protects Ochratoxin A-Induced Oxidative Stress and Apoptosis in the Heart via the Nrf2 Pathway.
Cui G, Li L, Xu W, Wang M, Jiao D, Yao B, Xu K, Chen Y, Yang S, Long M, Li P, Guo Y
Oxidative medicine and cellular longevity 2020;2020:7639109
Oxidative medicine and cellular longevity 2020;2020:7639109
Rhein Suppresses Neuroinflammation via Multiple Signaling Pathways in LPS-Stimulated BV2 Microglia Cells.
Zheng P, Tian X, Zhang W, Yang Z, Zhou J, Zheng J, Cui H, Tang T, Luo J, Wang Y
Evidence-based complementary and alternative medicine : eCAM 2020;2020:7210627
Evidence-based complementary and alternative medicine : eCAM 2020;2020:7210627
Adaptive Autophagy Offers Cardiorenal Protection in Rats with Acute Myocardial Infarction.
Feng Z, Jiang HX, Chen H, Liu YN, Wang Y, Yang RB, Han X, Xia CH, Zhu ZB, Shang H, Wu A, Liu WJ
Cardiology research and practice 2020;2020:7158975
Cardiology research and practice 2020;2020:7158975
Anticancer Activity of Tetrandrine by Inducing Apoptosis in Human Breast Cancer Cell Line MDA-MB-231 In Vivo.
Wang CH, Yang JM, Guo YB, Shen J, Pei XH
Evidence-based complementary and alternative medicine : eCAM 2020;2020:6823520
Evidence-based complementary and alternative medicine : eCAM 2020;2020:6823520
Tumor Necrosis Factor Receptor-Associated Protein 1 Protects against Mitochondrial Injury by Preventing High Glucose-Induced mPTP Opening in Diabetes.
Liu L, Zhang L, Zhao J, Guo X, Luo Y, Hu W, Zhao T
Oxidative medicine and cellular longevity 2020;2020:6431517
Oxidative medicine and cellular longevity 2020;2020:6431517
Curcumin Inhibits Proliferation and Epithelial-Mesenchymal Transition in Lens Epithelial Cells through Multiple Pathways.
Liu H, Mao Y, Xia B, Long C, Kuang X, Huang H, Ning J, Ma X, Zhang H, Wang R, Tang H, Du H, Yan J, Zhang Q, Zhang X, Shen H
BioMed research international 2020;2020:6061894
BioMed research international 2020;2020:6061894
Mild Hypothermia Attenuates Hepatic Ischemia-Reperfusion Injury through Regulating the JAK2/STAT3-CPT1a-Dependent Fatty Acid β-Oxidation.
Wang W, Hu X, Xia Z, Liu Z, Zhong Z, Lu Z, Liu A, Ye S, Cao Q, Wang Y, Zhu F, Ye Q
Oxidative medicine and cellular longevity 2020;2020:5849794
Oxidative medicine and cellular longevity 2020;2020:5849794
Plumbagin Enhances the Anticancer Efficacy of Cisplatin by Increasing Intracellular ROS in Human Tongue Squamous Cell Carcinoma.
Xue D, Pan ST, Zhou X, Ye F, Zhou Q, Shi F, He F, Yu H, Qiu J
Oxidative medicine and cellular longevity 2020;2020:5649174
Oxidative medicine and cellular longevity 2020;2020:5649174
NLRC3 Delays the Progression of AD in APP/PS1 Mice via Inhibiting PI3K Activation.
Zha L, Yu Z, Fang J, Zhou L, Guo W, Zhou J
Oxidative medicine and cellular longevity 2020;2020:5328031
Oxidative medicine and cellular longevity 2020;2020:5328031
Protective Effect of Simplicillium sp. Ethyl Acetate Extract against High Glucose-Induced Oxidative Stress in HUVECs.
Tian TT, Li QR, Gan SQ, Chang CR, Shen XC
Evidence-based complementary and alternative medicine : eCAM 2020;2020:5172765
Evidence-based complementary and alternative medicine : eCAM 2020;2020:5172765
The Class III PI3K/Beclin-1 Autophagic Pathway Participates in the mmLDL-Induced Upregulation of ETA Receptor in Mouse Mesenteric Arteries.
Xie X, Chen C, Xu CB, Lin J, Cao L, Chen G, Li J
Advances in pharmacological and pharmaceutical sciences 2020;2020:5070436
Advances in pharmacological and pharmaceutical sciences 2020;2020:5070436
Nei Endonuclease VIII-Like1 (NEIL1) Inhibits Apoptosis of Human Colorectal Cancer Cells.
Xue W, Liu Y, Xin N, Miao J, Du J, Wang Y, Shi H, Wei Y, Zhang H, Chen Y, Gao Y, Li D, Feng Y, Yan J, Zhang J, Hou N, Huang C, Han J
BioMed research international 2020;2020:5053975
BioMed research international 2020;2020:5053975
Baicalin Ameliorates Cognitive Impairment and Protects Microglia from LPS-Induced Neuroinflammation via the SIRT1/HMGB1 Pathway.
Li Y, Liu T, Li Y, Han D, Hong J, Yang N, He J, Peng R, Mi X, Kuang C, Zhou Y, Han Y, Shi C, Li Z, Guo X
Oxidative medicine and cellular longevity 2020;2020:4751349
Oxidative medicine and cellular longevity 2020;2020:4751349
Saponin from Periploca forrestii Schltr Mitigates Oxazolone-Induced Atopic Dermatitis via Modulating Macrophage Activation.
Zeng L, Liu Y, Xing C, Huang Y, Sun X, Sun G
Mediators of inflammation 2020;2020:4346367
Mediators of inflammation 2020;2020:4346367
Roux-en-Y Gastric Bypass in Obese Diabetic Rats Promotes Autophagy to Improve Lipid Metabolism through mTOR/p70S6K Signaling Pathway.
Ma N, Ma R, Tang K, Li X, He B
Journal of diabetes research 2020;2020:4326549
Journal of diabetes research 2020;2020:4326549
Obesity-Induced Upregulation of ZBTB7A Promotes Lipid Accumulation through SREBP1.
Zhou JP, Ren YD, Xu QY, Song Y, Zhou F, Chen MY, Liu JJ, Chen LG, Pan JS
BioMed research international 2020;2020:4087928
BioMed research international 2020;2020:4087928
Mining the Prognostic Value of HNRNPAB and Its Function in Breast Carcinoma.
Cao Y, Zhang W, Jin YT, Zou Q
International journal of genomics 2020;2020:3750673
International journal of genomics 2020;2020:3750673
Protective Role of Tangshen Formula on the Progression of Renal Damage in db/db Mice by TRPC6/Talin1 Pathway in Podocytes.
Wang Q, Tian X, Zhou W, Wang Y, Zhao H, Li J, Zhou X, Zhang H, Zhao T, Li P
Journal of diabetes research 2020;2020:3634974
Journal of diabetes research 2020;2020:3634974
Tianma Gouteng Decoction Exerts Cardiovascular Protection by Upregulating OPG and TRAIL in Spontaneously Hypertensive Rats.
Deng LH, Li L, Zhai Y, Michael S, Yang CY, Guo R, Chen SF, Fan GW, Zhao YQ, Liu W
Evidence-based complementary and alternative medicine : eCAM 2020;2020:3439191
Evidence-based complementary and alternative medicine : eCAM 2020;2020:3439191
Quantitative Analysis of the Proteome and the Succinylome in the Thyroid Tissue of High-Fat Diet-Induced Hypothyroxinemia in Rats.
Hu B, Zhao M, Luo D, Yu C, Shao S, Zhao L, Yang Y, Zhang X, Zhao J, Gao L
International journal of endocrinology 2020;2020:3240198
International journal of endocrinology 2020;2020:3240198
Prokineticin 2 (PK2) Rescues Cardiomyocytes from High Glucose/High Palmitic Acid-Induced Damage by Regulating the AKT/GSK3β Pathway In Vitro.
Yang Z, Wu Y, Wang L, Qiu P, Zha W, Yu W
Oxidative medicine and cellular longevity 2020;2020:3163629
Oxidative medicine and cellular longevity 2020;2020:3163629
Anticancer Activity of Modified Tongyou Decoction on Eca109 Esophageal Cancer Cell Invasion and Metastasis through Regulation of the Epithelial-Mesenchymal Transition Mediated by the HIF-1α-Snail Axis.
Jia Y, Yan X, Cao Y, Song W, Zhang G, Hu X
Evidence-based complementary and alternative medicine : eCAM 2020;2020:3053506
Evidence-based complementary and alternative medicine : eCAM 2020;2020:3053506
GDF15 Repression Contributes to 5-Fluorouracil Resistance in Human Colon Cancer by Regulating Epithelial-Mesenchymal Transition and Apoptosis.
Wang B, Ma N, Zheng X, Li X, Ma X, Hu J, Cao B
BioMed research international 2020;2020:2826010
BioMed research international 2020;2020:2826010
Ginsenoside Rg1 Alleviates Podocyte Injury Induced by Hyperlipidemia via Targeting the mTOR/NF-κB/NLRP3 Axis.
Wang T, Gao Y, Yue R, Wang X, Shi Y, Xu J, Wu B, Li Y
Evidence-based complementary and alternative medicine : eCAM 2020;2020:2735714
Evidence-based complementary and alternative medicine : eCAM 2020;2020:2735714
RRS1 Promotes Retinoblastoma Cell Proliferation and Invasion via Activating the AKT/mTOR Signaling Pathway.
Yan X, Wu S, Liu Q, Zhang J
BioMed research international 2020;2020:2420437
BioMed research international 2020;2020:2420437
Posttranslational Modification Defects in Fibroblast Growth Factor Receptor 1 as a Reason for Normosmic Isolated Hypogonadotropic Hypogonadism.
Ying H, Sun Y, Wu H, Jia W, Guan Q, He Z, Gao L, Zhao J, Ji Y, Li G, Xu C
Oxidative medicine and cellular longevity 2020;2020:2358719
Oxidative medicine and cellular longevity 2020;2020:2358719
OSCC Exosomes Regulate miR-210-3p Targeting EFNA3 to Promote Oral Cancer Angiogenesis through the PI3K/AKT Pathway.
Wang H, Wang L, Zhou X, Luo X, Liu K, Jiang E, Chen Y, Shao Z, Shang Z
BioMed research international 2020;2020:2125656
BioMed research international 2020;2020:2125656
Lipin1 Is Involved in the Pathogenesis of Diabetic Encephalopathy through the PKD/Limk/Cofilin Signaling Pathway.
Xie M, Wang M, Liu W, Xu M, Shang P, Jiang D, Ju L, Wu F, Sun A, Yu S, Zhuang X, Chen S
Oxidative medicine and cellular longevity 2020;2020:1723423
Oxidative medicine and cellular longevity 2020;2020:1723423
Silencing of PRDX2 Inhibits the Proliferation and Invasion of Non-Small Cell Lung Cancer Cells.
Jing X, Du L, Niu A, Wang Y, Wang Y, Wang C
BioMed research international 2020;2020:1276328
BioMed research international 2020;2020:1276328
Vagus Nerve Stimulation Alleviates Hepatic Ischemia and Reperfusion Injury by Regulating Glutathione Production and Transformation.
Xia H, Liu Z, Liang W, Zeng X, Yang Y, Chen P, Zhong Z, Ye Q
Oxidative medicine and cellular longevity 2020;2020:1079129
Oxidative medicine and cellular longevity 2020;2020:1079129
ADAM10 promotes cell growth, migration, and invasion in osteosarcoma via regulating E-cadherin/β-catenin signaling pathway and is regulated by miR-122-5p.
Yuan Q, Yu H, Chen J, Song X, Sun L
Cancer cell international 2020;20:99
Cancer cell international 2020;20:99
MYC-regulated lncRNA NEAT1 promotes B cell proliferation and lymphomagenesis via the miR-34b-5p-GLI1 pathway in diffuse large B-cell lymphoma.
Qian CS, Li LJ, Huang HW, Yang HF, Wu DP
Cancer cell international 2020;20:87
Cancer cell international 2020;20:87
Alantolactone inhibits cell autophagy and promotes apoptosis via AP2M1 in acute lymphoblastic leukemia.
Shi C, Lan W, Wang Z, Yang D, Wei J, Liu Z, Teng Y, Gu M, Yuan T, Cao F, Zhou J, Li Y
Cancer cell international 2020;20:442
Cancer cell international 2020;20:442
A novel chalcone derivative has antitumor activity in melanoma by inducing DNA damage through the upregulation of ROS products.
Li K, Zhao S, Long J, Su J, Wu L, Tao J, Zhou J, Zhang J, Chen X, Peng C
Cancer cell international 2020;20:36
Cancer cell international 2020;20:36
Downexpression of HSD17B6 correlates with clinical prognosis and tumor immune infiltrates in hepatocellular carcinoma.
Lv L, Zhao Y, Wei Q, Zhao Y, Yi Q
Cancer cell international 2020;20:210
Cancer cell international 2020;20:210
EphA5 knockdown enhances the invasion and migration ability of esophageal squamous cell carcinoma via epithelial-mesenchymal transition through activating Wnt/β-catenin pathway.
Zhang R, Liu J, Zhang W, Hua L, Qian LT, Zhou SB
Cancer cell international 2020;20:20
Cancer cell international 2020;20:20
MicroRNA-196b-5p promotes malignant progression of colorectal cancer by targeting ING5.
Xin H, Wang C, Chi Y, Liu Z
Cancer cell international 2020;20:119
Cancer cell international 2020;20:119
IL-21 promotes osteoblastic differentiation of human valvular interstitial cells through the JAK3/STAT3 pathway.
Liu Z, Wang Y, Shi J, Chen S, Xu L, Li F, Dong N
International journal of medical sciences 2020;17(18):3065-3072
International journal of medical sciences 2020;17(18):3065-3072
Interactome analysis of gene expression profiles identifies CDC6 as a potential therapeutic target modified by miR-215-5p in hepatocellular carcinoma.
Xu H, Huang J, Hua S, Liang L, He X, Zhan M, Lu L, Chu J
International journal of medical sciences 2020;17(18):2926-2940
International journal of medical sciences 2020;17(18):2926-2940
Fine Particulate Matter (PM2.5) upregulates expression of Inflammasome NLRP1 via ROS/NF-κB signaling in HaCaT Cells.
Dong L, Hu R, Yang D, Zhao J, Kan H, Tan J, Guan M, Kang Z, Xu F
International journal of medical sciences 2020;17(14):2200-2206
International journal of medical sciences 2020;17(14):2200-2206
Retinal dehydrogenase 5 (RHD5) attenuates metastasis via regulating HIPPO/YAP signaling pathway in Hepatocellular Carcinoma.
Hu H, Xu L, Luo SJ, Xiang T, Chen Y, Cao ZR, Zhang YJ, Mo Z, Wang Y, Meng DF, Yu L, Lin LZ, Zhang SJ
International journal of medical sciences 2020;17(13):1897-1908
International journal of medical sciences 2020;17(13):1897-1908
Polysaccharide extracted from WuGuChong reduces high-fat diet-induced obesity in mice by regulating the composition of intestinal microbiota.
Wang W, Zhong M, Yu T, Chen L, Shi L, Zong J, Wang S
Nutrition & metabolism 2020;17:27
Nutrition & metabolism 2020;17:27
Human follicular fluid proteome reveals association between overweight status and oocyte maturation abnormality.
Liu X, Wang Y, Zhu P, Wang J, Liu J, Li N, Wang W, Zhang W, Zhang C, Wang Y, Shen X, Liu F
Clinical proteomics 2020;17:22
Clinical proteomics 2020;17:22
Wnt5a/CaMKII/ERK/CCL2 axis is required for tumor-associated macrophages to promote colorectal cancer progression.
Liu Q, Song J, Pan Y, Shi D, Yang C, Wang S, Xiong B
International journal of biological sciences 2020;16(6):1023-1034
International journal of biological sciences 2020;16(6):1023-1034
Cdh1 functions as an oncogene by inducing self-renewal of lung cancer stem-like cells via oncogenic pathways.
Ye T, Li J, Sun Z, Liu D, Zeng B, Zhao Q, Wang J, Xing HR
International journal of biological sciences 2020;16(3):447-459
International journal of biological sciences 2020;16(3):447-459
Poly(U) binding splicing factor 60 promotes renal cell carcinoma growth by transcriptionally upregulating telomerase reverse transcriptase.
Long Q, Hua Y, He L, Zhang C, Sui S, Li Y, Qiu H, Tian T, An X, Luo G, Yan Y, Zhao A, Shi D, Xie F, Chen M, Zheng F, Deng W
International journal of biological sciences 2020;16(15):3002-3017
International journal of biological sciences 2020;16(15):3002-3017
Glucocorticoids improve severe or critical COVID-19 by activating ACE2 and reducing IL-6 levels.
Xiang Z, Liu J, Shi D, Chen W, Li J, Yan R, Bi Y, Hu W, Zhu Z, Yu Y, Yang Z
International journal of biological sciences 2020;16(13):2382-2391
International journal of biological sciences 2020;16(13):2382-2391
MFP-FePt-GO Nanocomposites Promote Radiosensitivity of Non-Small Cell Lung Cancer Via Activating Mitochondrial-Mediated Apoptosis and Impairing DNA Damage Repair.
Peng S, Sun Y, Luo Y, Ma S, Sun W, Tang G, Li S, Zhang N, Ren J, Xiao Y, Liu X, Zhang J, Gong Y, Xie C
International journal of biological sciences 2020;16(12):2145-2158
International journal of biological sciences 2020;16(12):2145-2158
Polysaccharides isolated from Cordyceps Sinensis contribute to the progression of NASH by modifying the gut microbiota in mice fed a high-fat diet.
Chen L, Zhang L, Wang W, Qiu W, Liu L, Ning A, Cao J, Huang M, Zhong M
PloS one 2020;15(6):e0232972
PloS one 2020;15(6):e0232972
Effects of miR-103 by negatively regulating SATB2 on proliferation and osteogenic differentiation of human bone marrow mesenchymal stem cells.
Lv H, Yang H, Wang Y
PloS one 2020;15(5):e0232695
PloS one 2020;15(5):e0232695
Decorin knockdown affects the gene expression profile of adhesion, growth and extracellular matrix metabolism in C-28/I2 chondrocytes.
Wang M, Li Z, Zhang M, Wang H, Zhang Y, Feng Y, Liu Y, Chen J
PloS one 2020;15(4):e0232321
PloS one 2020;15(4):e0232321
S100A6 promotes proliferation and migration of HepG2 cells via increased ubiquitin-dependent degradation of p53.
Song D, Xu B, Shi D, Li S, Cai Y
Open medicine (Warsaw, Poland) 2020;15(1):317-326
Open medicine (Warsaw, Poland) 2020;15(1):317-326
TiO2 Nanoparticles Caused DNA Damage in Lung and Extra-Pulmonary Organs Through ROS-Activated FOXO3a Signaling Pathway After Intratracheal Administration in Rats.
Han B, Pei Z, Shi L, Wang Q, Li C, Zhang B, Su X, Zhang N, Zhou L, Zhao B, Niu Y, Zhang R
International journal of nanomedicine 2020;15:6279-6294
International journal of nanomedicine 2020;15:6279-6294
Anticancer Effects of Zinc Oxide Nanoparticles Through Altering the Methylation Status of Histone on Bladder Cancer Cells.
Zhang T, Du E, Liu Y, Cheng J, Zhang Z, Xu Y, Qi S, Chen Y
International journal of nanomedicine 2020;15:1457-1468
International journal of nanomedicine 2020;15:1457-1468
Cardiac-Specific Caveolin-3 Overexpression Prevents Post-Myocardial Infarction Ventricular Arrhythmias by Inhibiting Ryanodine Receptor-2 Hyperphosphorylation.
Zhang Z, Fang Q, Du T, Chen G, Wang Y, Wang DW
Cardiology 2020;145(3):136-147
Cardiology 2020;145(3):136-147
Upregulation of C Terminus of Hsc70-Interacting Protein Attenuates Apoptosis and Procoagulant Activity and Facilitates Brain Repair After Traumatic Brain Injury.
Chen H, Jing Y, Xu Z, Yang D, Ju S, Guo Y, Tian H, Xue L
Frontiers in neuroscience 2020;14:925
Frontiers in neuroscience 2020;14:925
Oxymatrine Liposomes for Intervertebral Disc Treatment: Formulation, in vitro and vivo Assessments.
Wang H, Ding Y, Zhang W, Wei K, Pei Y, Zou C, Zhang C, Ding J, Fang H, Tan S
Drug design, development and therapy 2020;14:921-931
Drug design, development and therapy 2020;14:921-931
Plasmacytoid Dendritic Cells Protect Against Middle Cerebral Artery Occlusion Induced Brain Injury by Priming Regulatory T Cells.
Chen C, Chencheng Z, Cuiying L, Xiaokun G
Frontiers in cellular neuroscience 2020;14:8
Frontiers in cellular neuroscience 2020;14:8
Neuroprotection Against Parkinson's Disease Through the Activation of Akt/GSK3β Signaling Pathway by Tovophyllin A.
Huang Y, Sun L, Zhu S, Xu L, Liu S, Yuan C, Guo Y, Wang X
Frontiers in neuroscience 2020;14:723
Frontiers in neuroscience 2020;14:723
Neuroprotective Effect of Ketone Metabolism on Inhibiting Inflammatory Response by Regulating Macrophage Polarization After Acute Cervical Spinal Cord Injury in Rats.
Lin J, Huang Z, Liu J, Huang Z, Liu Y, Liu Q, Yang Z, Li R, Wu X, Shi Z, Zhu Q, Wu X
Frontiers in neuroscience 2020;14:583611
Frontiers in neuroscience 2020;14:583611
Effects of Saikosaponin D on CYP1A2 and CYP2D6 in HepaRG Cells.
Li H, Tang Y, Wang Y, Wei W, Yin C, Tang F
Drug design, development and therapy 2020;14:5251-5258
Drug design, development and therapy 2020;14:5251-5258
Combined Transplantation of Olfactory Ensheathing Cells With Rat Neural Stem Cells Enhanced the Therapeutic Effect in the Retina of RCS Rats.
Zhai W, Gao L, Qu L, Li Y, Zeng Y, Li Q, Xu H, Yin ZQ
Frontiers in cellular neuroscience 2020;14:52
Frontiers in cellular neuroscience 2020;14:52
Effect of Platelet-Activating Factor on Barrier Function of ARPE-19 Cells.
Zhang F, Liu L, Zhang H, Liu ZL
Drug design, development and therapy 2020;14:4205-4214
Drug design, development and therapy 2020;14:4205-4214
Metformin Inhibits Propofol-Induced Apoptosis of Mouse Hippocampal Neurons HT-22 Through Downregulating Cav-1.
Ge J, Huang Y, Zhang Y, Liu L, Gu T, Liu X, Yao L, Cai M, Sun J, Song J
Drug design, development and therapy 2020;14:1561-1569
Drug design, development and therapy 2020;14:1561-1569
Bergenin Exerts Hepatoprotective Effects by Inhibiting the Release of Inflammatory Factors, Apoptosis and Autophagy via the PPAR-γ Pathway.
Xiang S, Chen K, Xu L, Wang T, Guo C
Drug design, development and therapy 2020;14:129-143
Drug design, development and therapy 2020;14:129-143
RGFP966 Suppresses Tumor Growth and Migration Through Inhibition of EGFR Expression in Hepatocellular Carcinoma Cells in vitro.
Yu X, Yang F, Jiang H, Fan L
Drug design, development and therapy 2020;14:121-128
Drug design, development and therapy 2020;14:121-128
Cigarette smoke supports stemness and epithelial-mesenchymal transition in bladder cancer stem cells through SHH signaling.
Sun X, Song J, Li E, Geng H, Li Y, Yu D, Zhong C
International journal of clinical and experimental pathology 2020;13(6):1333-1348
International journal of clinical and experimental pathology 2020;13(6):1333-1348
Combination of astragaloside IV and ACEi ameliorates renal injuries in db/db mice.
Zhan H, Han P, Wang M, Wang Y, Weng W, Yu X, Yuan C, Li Y, Shao M, Sun H
International journal of clinical and experimental pathology 2020;13(5):827-836
International journal of clinical and experimental pathology 2020;13(5):827-836
FOXO1 and hsa-microRNA-204-5p affect the biologic behavior of MDA-MB-231 breast cancer cells.
Liang CY, Huang ZG, Tang ZQ, Xiao XL, Zeng JJ, Feng ZB
International journal of clinical and experimental pathology 2020;13(5):1146-1158
International journal of clinical and experimental pathology 2020;13(5):1146-1158
Kin17 knockdown suppresses the migration and invasion of cervical cancer cells through NF-κB-Snail pathway.
Zhong M, Liu Z, Wu K, Hong Z, Zhang Y, Qu J, Zhu C, Ou Z, Zeng T
International journal of clinical and experimental pathology 2020;13(3):607-615
International journal of clinical and experimental pathology 2020;13(3):607-615
Kelch-like protein 14 promotes proliferation and migration of ovarian cancer cells.
Chen Z, Wu M, Liu J
International journal of clinical and experimental pathology 2020;13(12):2950-2961
International journal of clinical and experimental pathology 2020;13(12):2950-2961
Overexpression of EPDR1 has an antitumorigenic effect on breast cancer in vitro.
Liang X, Bai J, Chen B
International journal of clinical and experimental pathology 2020;13(10):2628-2636
International journal of clinical and experimental pathology 2020;13(10):2628-2636
Clinical significance of focal adhesion kinase (FAK) in cervical cancer progression and metastasis.
Chen Y, Hu X, Yang S
International journal of clinical and experimental pathology 2020;13(10):2586-2592
International journal of clinical and experimental pathology 2020;13(10):2586-2592
MicroRNA-451a targets caveolin-1 in stomach cancer cells.
Wang Y, Lin Z, Song J, Wei S, Ye Z, Chen S, Zeng Y, Lin Z, Chen X, Chen L
International journal of clinical and experimental pathology 2020;13(10):2524-2533
International journal of clinical and experimental pathology 2020;13(10):2524-2533
Effect of the SIRT3-AMPK/PPAR pathway on invasion and migration of cervical cancer cells.
Xiao JB, Ma JQ, Yakefu K, Tursun M
International journal of clinical and experimental pathology 2020;13(10):2495-2501
International journal of clinical and experimental pathology 2020;13(10):2495-2501
Acupuncture Targeting SIRT1 in the Hypothalamic Arcuate Nucleus Can Improve Obesity in High-Fat-Diet-Induced Rats with Insulin Resistance via an Anorectic Effect.
Shu Q, Chen L, Wu S, Li J, Liu J, Xiao L, Chen R, Liang F
Obesity facts 2020;13(1):40-57
Obesity facts 2020;13(1):40-57
Circular RNA circNELL2 Acts as the Sponge of miR-127-5p to Promote Esophageal Squamous Cell Carcinoma Progression.
Xiong G, Diao D, Lu D, Liu X, Liu Z, Mai S, Feng S, Dong X, Cai K
OncoTargets and therapy 2020;13:9245-9255
OncoTargets and therapy 2020;13:9245-9255
TDO Promotes Hepatocellular Carcinoma Progression.
Li S, Li L, Wu J, Song F, Qin Z, Hou L, Xiao C, Weng J, Qin X, Xu J
OncoTargets and therapy 2020;13:5845-5855
OncoTargets and therapy 2020;13:5845-5855
TMED3 Promotes Proliferation and Migration in Breast Cancer Cells by Activating Wnt/β-Catenin Signaling.
Zhang X, Luo Y, Li Q
OncoTargets and therapy 2020;13:5819-5830
OncoTargets and therapy 2020;13:5819-5830
Characterization of Triple-Negative Breast Cancer MDA-MB-231 Cell Spheroid Model.
Huang Z, Yu P, Tang J
OncoTargets and therapy 2020;13:5395-5405
OncoTargets and therapy 2020;13:5395-5405
β-Elemene Enhances the Chemotherapeutic Effect of 5-Fluorouracil in Triple-Negative Breast Cancer via PI3K/AKT, RAF-MEK-ErK, and NF-κB Signaling Pathways.
Su P, Ahmad B, Zou K, Zou L
OncoTargets and therapy 2020;13:5207-5222
OncoTargets and therapy 2020;13:5207-5222
Diosgenin and GSK126 Produce Synergistic Effects on Epithelial-Mesenchymal Transition in Gastric Cancer Cells by Mediating EZH2 via the Rho/ROCK Signaling Pathway.
Liu S, Rong G, Li X, Geng L, Zeng Z, Jiang D, Yang J, Wei Y
OncoTargets and therapy 2020;13:5057-5067
OncoTargets and therapy 2020;13:5057-5067
Comprehensive Transcriptomic Analysis and Experimental Validation Identify lncRNA HOXA-AS2/miR-184/COL6A2 as the Critical ceRNA Regulation Involved in Low-Grade Glioma Recurrence.
Chen PY, Li XD, Ma WN, Li H, Li MM, Yang XY, Li SY
OncoTargets and therapy 2020;13:4999-5016
OncoTargets and therapy 2020;13:4999-5016
miR-877-5p Suppresses Gastric Cancer Cell Proliferation Through Targeting FOXM1.
Wu K, Yu Z, Tang Z, Wei W, Xie D, Xie Y, Xiao Q
OncoTargets and therapy 2020;13:4731-4742
OncoTargets and therapy 2020;13:4731-4742
FANCI Cooperates with IMPDH2 to Promote Lung Adenocarcinoma Tumor Growth via a MEK/ERK/MMPs Pathway.
Zheng P, Li L
OncoTargets and therapy 2020;13:451-463
OncoTargets and therapy 2020;13:451-463
DNMT1 Enhances the Radiosensitivity of HPV-Positive Head and Neck Squamous Cell Carcinomas via Downregulating SMG1.
Zhang C, Mi J, Deng Y, Deng Z, Long D, Liu Z
OncoTargets and therapy 2020;13:4201-4211
OncoTargets and therapy 2020;13:4201-4211
Microsatellite Instability-Related ACVR2A Mutations Partially Account for Decreased Lymph Node Metastasis in MSI-H Gastric Cancers.
Zhao L, Zhang J, Qu X, Yang Y, Gong Z, Yang Y, Wu Z, Guo W
OncoTargets and therapy 2020;13:3809-3821
OncoTargets and therapy 2020;13:3809-3821
GPR30 Promotes the Phenotypic Switching of Vascular Smooth Muscle Cells via Activating the AKT and ERK Pathways.
Zha B, Qiu P, Zhang C, Li X, Chen Z
OncoTargets and therapy 2020;13:3801-3808
OncoTargets and therapy 2020;13:3801-3808
Low-Dose Radiation Promotes Invasion and Migration of A549 Cells by Activating the CXCL1/NF-κB Signaling Pathway.
Li J, Wu DM, Han R, Yu Y, Deng SH, Liu T, Zhang T, Xu Y
OncoTargets and therapy 2020;13:3619-3629
OncoTargets and therapy 2020;13:3619-3629
Cbl Proto-Oncogene B (CBLB) c.197A>T Mutation Induces Mild Metabolic Dysfunction in Partial Type I Multiple Symmetric Lipomatosis (MSL).
Chen K, Wan X, Zhao L, Zhao S, Peng L, Yang W, Yuan J, Zhu L, Mo Z
Diabetes, metabolic syndrome and obesity : targets and therapy 2020;13:3535-3549
Diabetes, metabolic syndrome and obesity : targets and therapy 2020;13:3535-3549
RCC2 Interacts with Small GTPase RalA and Regulates Cell Proliferation and Motility in Gastric Cancer.
Wang P, Zhang W, Wang L, Liang W, Cai A, Gao Y, Chen L
OncoTargets and therapy 2020;13:3093-3103
OncoTargets and therapy 2020;13:3093-3103
RSF-1 siRNA Enhances Tumor Radiosensitivity in Cervical Cancer via Enhanced DNA Damage, Cell Cycle Redistribution, and Promotion of Apoptosis.
Tian J, Kong E, Wang X, Xie Z, Chang CY, Sheu JJ, Hao Q, Sun L
OncoTargets and therapy 2020;13:3061-3071
OncoTargets and therapy 2020;13:3061-3071
Long Non-Coding RNA SPRY4-IT1 Reverses Cisplatin Resistance by Downregulating MPZL-1 via Suppressing EMT in NSCLC.
Ye Y, Gu J, Liu P, Wang H, Jiang L, Lei T, Yu S, Han G, Wang Z
OncoTargets and therapy 2020;13:2783-2793
OncoTargets and therapy 2020;13:2783-2793
Tumor Suppressor microRNA-138 Suppresses Low-Grade Glioma Development and Metastasis via Regulating IGF2BP2.
Yang Y, Liu X, Cheng L, Li L, Wei Z, Wang Z, Han G, Wan X, Wang Z, Zhang J, Chen C
OncoTargets and therapy 2020;13:2247-2260
OncoTargets and therapy 2020;13:2247-2260
Circular RNA 0001313 Knockdown Suppresses Non-Small Cell Lung Cancer Cell Proliferation and Invasion via the microRNA-452/HMGB3/ERK/MAPK Axis.
Zhang S, Liu J, Yuan T, Liu H, Wan C, Le Y
International journal of general medicine 2020;13:1495-1507
International journal of general medicine 2020;13:1495-1507
Knockdown of Circular RNA Hsa_circ_0000714 Can Regulate RAB17 by Sponging miR-370-3p to Reduce Paclitaxel Resistance of Ovarian Cancer Through CDK6/RB Pathway.
Guo M, Li S, Zhao X, Yuan Y, Zhang B, Guan Y
OncoTargets and therapy 2020;13:13211-13224
OncoTargets and therapy 2020;13:13211-13224
DUSP9 Suppresses Proliferation and Migration of Clear Cell Renal Cell Carcinoma via the mTOR Pathway.
Luo J, Luo X, Liu X, Fang Z, Xu J, Li L
OncoTargets and therapy 2020;13:1321-1330
OncoTargets and therapy 2020;13:1321-1330
Hsa_circRNA_100146 Acts as a Sponge of miR-149-5p in Promoting Bladder Cancer Progression via Regulating RNF2.
Wang H, Niu X, Mao F, Liu X, Zhong B, Jiang H, Fu G
OncoTargets and therapy 2020;13:11007-11017
OncoTargets and therapy 2020;13:11007-11017
Overexpression of RNF126 Promotes the Development of Colorectal Cancer via Enhancing p53 Ubiquitination and Degradation.
Wang S, Wang T, Wang L, Zhong L, Li K
OncoTargets and therapy 2020;13:10917-10929
OncoTargets and therapy 2020;13:10917-10929
17-Allylamino-Demethoxygeldanamycin Ameliorate Microthrombosis Via HSP90/RIP3/NLRP3 Pathway After Subarachnoid Hemorrhage in Rats.
Zuo Y, He T, Liao P, Zhuang K, Yan X, Liu F
Acta neurochirurgica. Supplement 2020;127:69-75
Acta neurochirurgica. Supplement 2020;127:69-75
lncRNA USP2-AS1 promotes colon cancer progression by modulating Hippo/YAP1 signaling.
Li D, Bao J, Yao J, Li J
American journal of translational research 2020;12(9):5670-5682
American journal of translational research 2020;12(9):5670-5682
β-catenin regulates myocardial ischemia/reperfusion injury following heterotopic heart transplantation in mice by modulating PTEN pathways.
Ban Q, Qiao L, Xia H, Xie B, Liu J, Ma Y, Zhang L, Zhang M, Liu LG, Jiao W, Yang S, Li Z, Zheng S, Liu D, Xia J, Qi Z
American journal of translational research 2020;12(8):4757-4771
American journal of translational research 2020;12(8):4757-4771
Homocysteine-induced electrical remodeling via the mediation of IP3R1/Nav1.5 signaling pathway.
Han L, Wu A, Li Q, Xia Z, Wu Y, Hong K, Xia Z, Li J
American journal of translational research 2020;12(7):3822-3841
American journal of translational research 2020;12(7):3822-3841
Astragaloside IV alleviates puromycin aminonucleoside-induced podocyte cytoskeleton injury through the Wnt/PCP pathway.
Zeng Y, Zhang B, Liu X, He L, Wang T, Yu X, Kang Y, Li S
American journal of translational research 2020;12(7):3512-3521
American journal of translational research 2020;12(7):3512-3521
CircAPLP2 regulates the proliferation and metastasis of colorectal cancer by targeting miR-101-3p to activate the Notch signalling pathway.
Wu HB, Huang SS, Lu CG, Tian SD, Chen M
American journal of translational research 2020;12(6):2554-2569
American journal of translational research 2020;12(6):2554-2569
Huangqi-Danshen decoction alleviates diabetic nephropathy in db/db mice by inhibiting PINK1/Parkin-mediated mitophagy.
Liu X, Lu J, Liu S, Huang D, Chen M, Xiong G, Li S
American journal of translational research 2020;12(3):989-998
American journal of translational research 2020;12(3):989-998
Kaempferol attenuated cisplatin-induced cardiac injury via inhibiting STING/NF-κB-mediated inflammation.
Qi Y, Ying Y, Zou J, Fang Q, Yuan X, Cao Y, Cai Y, Fu S
American journal of translational research 2020;12(12):8007-8018
American journal of translational research 2020;12(12):8007-8018
Enzastaurin enhances ATRA-induced differentiation of acute myeloid leukemia cells.
Li ZY, Liang C, Ding M, Weng XQ, Sheng Y, Wu J, Lu H, Cai X
American journal of translational research 2020;12(12):7836-7854
American journal of translational research 2020;12(12):7836-7854
Polydopamine coating with static magnetic field promotes the osteogenic differentiation of human bone-derived mesenchymal stem cells on three-dimensional printed porous titanium scaffolds by upregulation of the BMP-Smads signaling pathway.
Kong L, Han Y, Lu Q, Zhou D, Wang B, Wang D, Zhang W, Xiang H, Li M, Wang F
American journal of translational research 2020;12(12):7812-7825
American journal of translational research 2020;12(12):7812-7825
EphA5 Silencing Increases the Radiosensitivity of ESCC Cells Through ATM-Dependent Pathway.
Zhang R, Han D, Li L, Luo W, Liu J, Qian L
Cancer management and research 2020;12:9539-9549
Cancer management and research 2020;12:9539-9549
miR-758-3p Inhibits Proliferation, Migration, and Invasion of Clear Cell Renal Cell Carcinoma and Predicts Favorable Prognosis.
Wu Y, Liu Y
Cancer management and research 2020;12:9285-9295
Cancer management and research 2020;12:9285-9295
Exosome-Reversed Chemoresistance to Cisplatin in Non-Small Lung Cancer Through Transferring miR-613.
Li D, Meng D, Niu R
Cancer management and research 2020;12:7961-7972
Cancer management and research 2020;12:7961-7972
miR-31-5p Regulates 14-3-3 ɛ to Inhibit Prostate Cancer 22RV1 Cell Survival and Proliferation via PI3K/AKT/Bcl-2 Signaling Pathway.
Zhao J, Xu H, Duan Z, Chen X, Ao Z, Chen Y, Ruan Y, Ni M
Cancer management and research 2020;12:6679-6694
Cancer management and research 2020;12:6679-6694
MiTF is Associated with Chemoresistance to Cisplatin in A549 Lung Cancer Cells via Modulating Lysosomal Biogenesis and Autophagy.
Li W, Qin X, Wang B, Xu G, Zhang J, Jiang X, Chen C, Qiu F, Zou Z
Cancer management and research 2020;12:6563-6573
Cancer management and research 2020;12:6563-6573
Class I HDAC Inhibitor Improves Synaptic Proteins and Repairs Cytoskeleton Through Regulating Synapse-Related Genes In vitro and In vivo.
Han Y, Chen L, Guo Y, Wang C, Zhang C, Kong L, Ma H
Frontiers in aging neuroscience 2020;12:619866
Frontiers in aging neuroscience 2020;12:619866
FTY720 Prevents Spatial Memory Impairment in a Rat Model of Chronic Cerebral Hypoperfusion via a SIRT3-Independent Pathway.
Zhang M, Hu Y, Zhang J, Zhang J
Frontiers in aging neuroscience 2020;12:593364
Frontiers in aging neuroscience 2020;12:593364
The Requirement of the C-Terminal Domain of GluA1 in Different Forms of Long-Term Potentiation in the Hippocampus Is Age-Dependent.
Liu A, Ji H, Ren Q, Meng Y, Zhang H, Collingride G, Xie W, Jia Z
Frontiers in synaptic neuroscience 2020;12:588785
Frontiers in synaptic neuroscience 2020;12:588785
Glucosamine-6-Phosphate Isomerase 1 Promotes Tumor Progression and Indicates Poor Prognosis in Hepatocellular Carcinoma.
Li D, Cheng X, Zheng W, Chen J
Cancer management and research 2020;12:4923-4935
Cancer management and research 2020;12:4923-4935
Down-regulation of USP8 Inhibits Cholangiocarcinoma Cell Proliferation and Invasion.
Jing X, Chen Y, Chen Y, Shi G, Lv S, Cheng N, Feng C, Xin Z, Zhang L, Wu J
Cancer management and research 2020;12:2185-2194
Cancer management and research 2020;12:2185-2194
AOC1 Contributes to Tumor Progression by Promoting the AKT and EMT Pathways in Gastric Cancer.
Xu F, Xu Y, Xiong JH, Zhang JH, Wu J, Luo J, Xiong JP
Cancer management and research 2020;12:1789-1798
Cancer management and research 2020;12:1789-1798
MicroRNA-1276 Promotes Colon Cancer Cell Proliferation by Negatively Regulating LACTB.
Wang C, Shi Z, Hong Z, Pan J, Chen Z, Qiu C, Zhuang H, Zheng X
Cancer management and research 2020;12:12185-12195
Cancer management and research 2020;12:12185-12195
Hyperin Controls the Development and Therapy of Gastric Cancer via Regulating Wnt/β-Catenin Signaling.
Ping MH
Cancer management and research 2020;12:11773-11782
Cancer management and research 2020;12:11773-11782
MicroRNA-802 Suppresses Tumorigenesis of Colorectal Cancer via Regulating UBN2.
Yang T, Guo Q, Li D, Bai G, Sun H, Wang W
Cancer management and research 2020;12:11219-11230
Cancer management and research 2020;12:11219-11230
miR-302e Suppresses Glioma Progression by Targeting VEGFA.
Xie Y, Liu X, Hu T, Wang W
Cancer management and research 2020;12:10965-10974
Cancer management and research 2020;12:10965-10974
Exosomes derived from 5-fluorouracil-resistant colon cancer cells are enriched in GDF15 and can promote angiogenesis.
Zheng X, Ma N, Wang X, Hu J, Ma X, Wang J, Cao B
Journal of Cancer 2020;11(24):7116-7126
Journal of Cancer 2020;11(24):7116-7126
NFE2L3 promotes malignant behavior and EMT of human hepatocellular carcinoma (HepG2) cells via Wnt/β‑catenin pathway.
Ren Y, Wang Y, Hao S, Yang Y, Xiong W, Qiu L, Tao J, Tang A
Journal of Cancer 2020;11(23):6939-6949
Journal of Cancer 2020;11(23):6939-6949
Ligand-independent EphB1 signaling mediates TGF-β-activated CDH2 and promotes lung cancer cell invasion and migration.
Wang L, Peng Q, Sai B, Zheng L, Xu J, Yin N, Feng X, Xiang J
Journal of Cancer 2020;11(14):4123-4131
Journal of Cancer 2020;11(14):4123-4131
Analysis of Differentially Expressed Genes in a Chinese Cohort of Esophageal Squamous Cell Carcinoma.
Liu G, Zhao Y, Chen H, Jia J, Cheng X, Wang F, Ji Q, Thorne RF, Chen S, Liu X
Journal of Cancer 2020;11(13):3783-3793
Journal of Cancer 2020;11(13):3783-3793
Caffeic Acid Phenethyl Ester Ameliorates Calcification by Inhibiting Activation of the AKT/NF-κB/NLRP3 Inflammasome Pathway in Human Aortic Valve Interstitial Cells.
Liu M, Li F, Huang Y, Zhou T, Chen S, Li G, Shi J, Dong N, Xu K
Frontiers in pharmacology 2020;11:826
Frontiers in pharmacology 2020;11:826
UVA Induced Oxidative Stress Was Inhibited by Paeoniflorin/Nrf2 Signaling or PLIN2.
Lu YS, Jiang Y, Yuan JP, Jiang SB, Yang Y, Zhu PY, Sun YZ, Qi RQ, Liu T, Wang HX, Wu Y, Gao XH, Chen HD
Frontiers in pharmacology 2020;11:736
Frontiers in pharmacology 2020;11:736
Gelatinases Cleave Dentin Sialoprotein Intracellularly.
Gou X, Xue Y, Zheng H, Yang G, Chen S, Chen Z, Yuan G
Frontiers in physiology 2020;11:686
Frontiers in physiology 2020;11:686
Salvianolic Acid A Has Anti-Osteoarthritis Effect In Vitro and In Vivo.
Wu Y, Wang Z, Lin Z, Fu X, Zhan J, Yu K
Frontiers in pharmacology 2020;11:682
Frontiers in pharmacology 2020;11:682
Notch3 Modulates Cardiac Fibroblast Proliferation, Apoptosis, and Fibroblast to Myofibroblast Transition via Negative Regulation of the RhoA/ROCK/Hif1α Axis.
Shi J, Xiao P, Liu X, Chen Y, Xu Y, Fan J, Yin Y
Frontiers in physiology 2020;11:669
Frontiers in physiology 2020;11:669
Obg-Like ATPase 1 Enhances Chemoresistance of Breast Cancer via Activation of TGF-β/Smad Axis Cascades.
Liu J, Miao X, Xiao B, Huang J, Tao X, Zhang J, Zhao H, Pan Y, Wang H, Gao G, Xiao GG
Frontiers in pharmacology 2020;11:666
Frontiers in pharmacology 2020;11:666
Ursolic Acid Regulates Cell Cycle and Proliferation in Colon Adenocarcinoma by Suppressing Cyclin B1.
Yang M, Hu C, Cao Y, Liang W, Yang X, Xiao T
Frontiers in pharmacology 2020;11:622212
Frontiers in pharmacology 2020;11:622212
Pristimerin Suppresses RANKL-Induced Osteoclastogenesis and Ameliorates Ovariectomy-Induced Bone Loss.
Qi D, Liu H, Sun X, Luo D, Zhu M, Tao T, Gao C, Zhou C, Zhou W, Xiao J
Frontiers in pharmacology 2020;11:621110
Frontiers in pharmacology 2020;11:621110
Integrating Network Pharmacology and Experimental Validation to Investigate the Effects and Mechanism of Astragalus Flavonoids Against Hepatic Fibrosis.
An L, Lin Y, Li L, Kong M, Lou Y, Wu J, Liu Z
Frontiers in pharmacology 2020;11:618262
Frontiers in pharmacology 2020;11:618262
Butylphthalide Inhibits Autophagy and Promotes Multiterritory Perforator Flap Survival.
Li B, Chen Z, Luo X, Zhang C, Chen H, Wang S, Zhao M, Ma H, Liu J, Cheng M, Yang Y, Yan H
Frontiers in pharmacology 2020;11:612932
Frontiers in pharmacology 2020;11:612932
Role of GABRD Gene Methylation in the Nucleus Accumbens in Heroin-Seeking Behavior in Rats.
Hong Q, Xu W, Lin Z, Liu J, Chen W, Zhu H, Lai M, Zhuang D, Xu Z, Fu D, Zhou W, Liu H
Frontiers in pharmacology 2020;11:612200
Frontiers in pharmacology 2020;11:612200
Elucidation of the Mechanism of Action of Ginseng Against Acute Lung Injury/Acute Respiratory Distress Syndrome by a Network Pharmacology-Based Strategy.
Ding Q, Zhu W, Diao Y, Xu G, Wang L, Qu S, Shi Y
Frontiers in pharmacology 2020;11:611794
Frontiers in pharmacology 2020;11:611794
Isorhamnetin Enhances the Radiosensitivity of A549 Cells Through Interleukin-13 and the NF-κB Signaling Pathway.
Du Y, Jia C, Liu Y, Li Y, Wang J, Sun K
Frontiers in pharmacology 2020;11:610772
Frontiers in pharmacology 2020;11:610772
A Rare KIF1A Missense Mutation Enhances Synaptic Function and Increases Seizure Activity.
Guo Y, Chen Y, Yang M, Xu X, Lin Z, Ma J, Chen H, Hu Y, Ma Y, Wang X, Tian X
Frontiers in genetics 2020;11:61
Frontiers in genetics 2020;11:61
Oleoylethanolamide Protects Against Acute Liver Injury by Regulating Nrf-2/HO-1 and NLRP3 Pathways in Mice.
Hu J, Zhu Z, Ying H, Yao J, Ma H, Li L, Zhao Y
Frontiers in pharmacology 2020;11:605065
Frontiers in pharmacology 2020;11:605065
Stimulation of Vibratory Urticaria-Associated Adhesion-GPCR, EMR2/ADGRE2, Triggers the NLRP3 Inflammasome Activation Signal in Human Monocytes.
I KY, Tseng WY, Wang WC, Gordon S, Ng KF, Lin HH
Frontiers in immunology 2020;11:602016
Frontiers in immunology 2020;11:602016
Isoquercitrin Ameliorates Cisplatin-Induced Nephrotoxicity Via the Inhibition of Apoptosis, Inflammation, and Oxidative Stress.
Wang H, Xia W, Long G, Pei Z, Li Y, Wu M, Wang Q, Zhang Y, Jia Z, Chen H
Frontiers in pharmacology 2020;11:599416
Frontiers in pharmacology 2020;11:599416
Poly(dA:dT) Suppresses HSV-2 Infection of Human Cervical Epithelial Cells Through RIG-I Activation.
Shao DD, Meng FZ, Liu Y, Xu XQ, Wang X, Hu WH, Hou W, Ho WZ
Frontiers in immunology 2020;11:598884
Frontiers in immunology 2020;11:598884
A Longitudinal Study of T2 Mapping Combined With Diffusion Tensor Imaging to Quantitatively Evaluate Tissue Repair of Rat Skeletal Muscle After Frostbite.
Gao Y, Lu Z, Lyu X, Liu Q, Pan S
Frontiers in physiology 2020;11:597638
Frontiers in physiology 2020;11:597638
Human Umbilical Cord Mesenchymal Stem Cell Differentiation Into Odontoblast-Like Cells and Endothelial Cells: A Potential Cell Source for Dental Pulp Tissue Engineering.
Zhang S, Zhang W, Li Y, Ren L, Deng H, Yin X, Gao X, Pan S, Niu Y
Frontiers in physiology 2020;11:593
Frontiers in physiology 2020;11:593
Tanshinone IIA Inhibits Epithelial-to-Mesenchymal Transition Through Hindering β-Arrestin1 Mediated β-Catenin Signaling Pathway in Colorectal Cancer.
Song Q, Yang L, Han Z, Wu X, Li R, Zhou L, Liu N, Sui H, Cai J, Wang Y, Ji Q, Li Q
Frontiers in pharmacology 2020;11:586616
Frontiers in pharmacology 2020;11:586616
MiR-497-5p Regulates Osteo/Odontogenic Differentiation of Stem Cells From Apical Papilla via the Smad Signaling Pathway by Targeting Smurf2.
Liu J, Wang X, Song M, Du J, Yu J, Zheng W, Zhang C, Wang Y
Frontiers in genetics 2020;11:582366
Frontiers in genetics 2020;11:582366
A Novel Transcript Isoform of TBK1 Negatively Regulates Type I IFN Production by Promoting Proteasomal Degradation of TBK1 and Lysosomal Degradation of IRF3.
Zhang J, Wu XM, Hu YW, Chang MX
Frontiers in immunology 2020;11:580864
Frontiers in immunology 2020;11:580864
Seneca Valley Virus 3C Protease Inhibits Stress Granule Formation by Disrupting eIF4GI-G3BP1 Interaction.
Wen W, Zhao Q, Yin M, Qin L, Hu J, Chen H, Li X, Qian P
Frontiers in immunology 2020;11:577838
Frontiers in immunology 2020;11:577838
Evodiamine Attenuates Experimental Colitis Injury Via Activating Autophagy and Inhibiting NLRP3 Inflammasome Assembly.
Ding W, Ding Z, Wang Y, Zhu Y, Gao Q, Cao W, Du R
Frontiers in pharmacology 2020;11:573870
Frontiers in pharmacology 2020;11:573870
Chidamide Inhibits Acute Myeloid Leukemia Cell Proliferation by lncRNA VPS9D1-AS1 Downregulation via MEK/ERK Signaling Pathway.
Lin L, Que Y, Lu P, Li H, Xiao M, Zhu X, Li D
Frontiers in pharmacology 2020;11:569651
Frontiers in pharmacology 2020;11:569651
Transcriptomic Analysis of Glycolysis-Related Genes Reveals an Independent Signature of Bladder Carcinoma.
Mou Z, Yang C, Zhang Z, Wu S, Xu C, Cheng Z, Dai X, Chen X, Ou Y, Jiang H
Frontiers in genetics 2020;11:566918
Frontiers in genetics 2020;11:566918
Sleep Deprivation Induces Cognitive Impairment by Increasing Blood-Brain Barrier Permeability via CD44.
Sun J, Wu J, Hua F, Chen Y, Zhan F, Xu G
Frontiers in neurology 2020;11:563916
Frontiers in neurology 2020;11:563916
Protective effects of taurine against muscle damage induced by diquat in 35 days weaned piglets.
Wen C, Li F, Guo Q, Zhang L, Duan Y, Wang W, Li J, He S, Chen W, Yin Y
Journal of animal science and biotechnology 2020;11:56
Journal of animal science and biotechnology 2020;11:56
The Endogenous Alterations of the Gut Microbiota and Feces Metabolites Alleviate Oxidative Damage in the Brain of LanCL1 Knockout Mice.
Zhang F, Qi N, Zeng Y, Bao M, Chen Y, Liao J, Wei L, Cao D, Huang S, Luo Q, Jiang Y, Mo Z
Frontiers in microbiology 2020;11:557342
Frontiers in microbiology 2020;11:557342
Protective Effects and Possible Mechanisms of Actions of Bushen Cuyun Recipe on Diminished Ovarian Reserve Induced by Cyclophosphamide in Rats.
Jiang M, Wang W, Zhang J, Wang C, Bi Y, Li P, Yang S, Li J, Xu YT, Wang T
Frontiers in pharmacology 2020;11:546
Frontiers in pharmacology 2020;11:546
Mechanical Stretch Induces Smooth Muscle Cell Dysfunction by Regulating ACE2 via P38/ATF3 and Post-transcriptional Regulation by miR-421.
Liu X, Liu X, Li M, Zhang Y, Chen W, Zhang M, Zhang C, Zhang M
Frontiers in physiology 2020;11:540591
Frontiers in physiology 2020;11:540591
Hepatitis B Core Antigen Impairs the Polarization While Promoting the Production of Inflammatory Cytokines of M2 Macrophages via the TLR2 Pathway.
Yi H, Zhang Y, Yang X, Li M, Hu H, Xiong J, Wang N, Jin J, Zhang Y, Song Y, Wang X, Chen L, Lian J
Frontiers in immunology 2020;11:535
Frontiers in immunology 2020;11:535
Investigation of the Lipid-Lowering Mechanisms and Active Ingredients of Danhe Granule on Hyperlipidemia Based on Systems Pharmacology.
Chen K, Ma Z, Yan X, Liu J, Xu W, Li Y, Dai Y, Zhang Y, Xiao H
Frontiers in pharmacology 2020;11:528
Frontiers in pharmacology 2020;11:528
Lian Hua Qing Wen Capsules, a Potent Epithelial Protector in Acute Lung Injury Model, Block Proapoptotic Communication Between Macrophages, and Alveolar Epithelial Cells.
Li Q, Ran Q, Sun L, Yin J, Luo T, Liu L, Zhao Z, Yang Q, Li Y, Chen Y, Weng X, Wang Y, Cai W, Zhu X
Frontiers in pharmacology 2020;11:522729
Frontiers in pharmacology 2020;11:522729
Differential Expression and Alternative Splicing of Transcripts Associated With Cisplatin-Induced Chemoresistance in Nasopharyngeal Carcinoma.
Zhang J, Jiang H, Xie T, Zheng J, Tian Y, Li R, Wang B, Lin J, Xu A, Huang X, Yuan Y
Frontiers in genetics 2020;11:52
Frontiers in genetics 2020;11:52
Fibroblast Growth Factor 1 Ameliorates Diabetes-Induced Liver Injury by Reducing Cellular Stress and Restoring Autophagy.
Xu Z, Wu Y, Wang F, Li X, Wang P, Li Y, Wu J, Li Y, Jiang T, Pan X, Zhang X, Xie L, Xiao J, Liu Y
Frontiers in pharmacology 2020;11:52
Frontiers in pharmacology 2020;11:52
C-X-C Motif Chemokine 10 Contributes to the Development of Neuropathic Pain by Increasing the Permeability of the Blood-Spinal Cord Barrier.
Li HL, Huang Y, Zhou YL, Teng RH, Zhou SZ, Lin JP, Yang Y, Zhu SM, Xu H, Yao YX
Frontiers in immunology 2020;11:477
Frontiers in immunology 2020;11:477
Antimicrobial Role of RNASET2 Protein During Innate Immune Response in the Medicinal Leech Hirudo verbana.
Baranzini N, De Vito A, Orlandi VT, Reguzzoni M, Monti L, de Eguileor M, Rosini E, Pollegioni L, Tettamanti G, Acquati F, Grimaldi A
Frontiers in immunology 2020;11:370
Frontiers in immunology 2020;11:370
Single-Anastomosis Duodenal Jejunal Bypass Improve Glucose Metabolism by Regulating Gut Microbiota and Short-Chain Fatty Acids in Goto-Kakisaki Rats.
Yu X, Wu Z, Song Z, Zhang H, Zhan J, Yu H, Huang H, Yang B, Xie L, Dai X, Zhao W, Yu J, Wu L
Frontiers in microbiology 2020;11:273
Frontiers in microbiology 2020;11:273
Reduced Let-7f in Bone Marrow-Derived Mesenchymal Stem Cells Triggers Treg/Th17 Imbalance in Patients With Systemic Lupus Erythematosus.
Geng L, Tang X, Wang S, Sun Y, Wang D, Tsao BP, Feng X, Sun L
Frontiers in immunology 2020;11:233
Frontiers in immunology 2020;11:233
Tilianin Extracted From Dracocephalum moldavica L. Induces Intrinsic Apoptosis and Drives Inflammatory Microenvironment Response on Pharyngeal Squamous Carcinoma Cells via Regulating TLR4 Signaling Pathways.
Jiang H, Zeng L, Dong X, Guo S, Xing J, Li Z, Liu R
Frontiers in pharmacology 2020;11:205
Frontiers in pharmacology 2020;11:205
HPV16 E6/E7 promote the translocation and glucose uptake of GLUT1 by PI3K/AKT pathway via relieving miR-451 inhibitory effect on CAB39 in lung cancer cells.
Wang HM, Lu YJ, He L, Gu NJ, Wang SY, Qiu XS, Wang EH, Wu GP
Therapeutic advances in chronic disease 2020;11:2040622320957143
Therapeutic advances in chronic disease 2020;11:2040622320957143
Scutellarein inhibits BLM-mediated pulmonary fibrosis by affecting fibroblast differentiation, proliferation, and apoptosis.
Miao K, Pan T, Mou Y, Zhang L, Xiong W, Xu Y, Yu J, Wang Y
Therapeutic advances in chronic disease 2020;11:2040622320940185
Therapeutic advances in chronic disease 2020;11:2040622320940185
Critical Role of AdipoR1 in Regulating Th17 Cell Differentiation Through Modulation of HIF-1α-Dependent Glycolysis.
Zhang Q, Wang L, Jiang J, Lin S, Luo A, Zhao P, Tan W, Zhang M
Frontiers in immunology 2020;11:2040
Frontiers in immunology 2020;11:2040
Treatment and Prevention of Lung Cancer Using a Virus-Infected Reprogrammed Somatic Cell-Derived Tumor Cell Vaccination (VIReST) Regime.
Zhang Z, Lu S, Dunmall LSC, Wang Z, Cheng Z, Zhang Z, Yan W, Chu Y, Gao D, Wang N, Li Y, Wang J, Li Y, Ji Y, Shan D, Li K, Wang P, Dong Y, Dong J, Lemoine NR, Pei D, Zhang L, Wang Y
Frontiers in immunology 2020;11:1996
Frontiers in immunology 2020;11:1996
MiR-362-5p, Which Is Regulated by Long Non-Coding RNA MBNL1-AS1, Promotes the Cell Proliferation and Tumor Growth of Bladder Cancer by Targeting QKI.
Wei X, Wang B, Wang Q, Yang X, Yang Y, Fang Z, Yi C, Shi L, Fan X, Tao J, Guo Y, Song D
Frontiers in pharmacology 2020;11:164
Frontiers in pharmacology 2020;11:164
Csf2 Attenuated Sepsis-Induced Acute Kidney Injury by Promoting Alternative Macrophage Transition.
Li Y, Zhai P, Zheng Y, Zhang J, Kellum JA, Peng Z
Frontiers in immunology 2020;11:1415
Frontiers in immunology 2020;11:1415
Combined Proteome and Transcriptome Analysis of Heat-Primed Azalea Reveals New Insights Into Plant Heat Acclimation Memory.
Wang X, Li Z, Liu B, Zhou H, Elmongy MS, Xia Y
Frontiers in plant science 2020;11:1278
Frontiers in plant science 2020;11:1278
Maimendong Decoction Improves Pulmonary Function in Rats With Idiopathic Pulmonary Fibrosis by Inhibiting Endoplasmic Reticulum Stress in AECIIs.
Shen M, Nan Y, Zhang L, Di L, He S, Li Y, Li Y
Frontiers in pharmacology 2020;11:1262
Frontiers in pharmacology 2020;11:1262
The Protective Effect of Luteolin in Glucocorticoid-Induced Osteonecrosis of the Femoral Head.
Yan Z, Zhan J, Qi W, Lin J, Huang Y, Xue X, Pan X
Frontiers in pharmacology 2020;11:1195
Frontiers in pharmacology 2020;11:1195
Gallic Acid Attenuates Angiotensin II-Induced Hypertension and Vascular Dysfunction by Inhibiting the Degradation of Endothelial Nitric Oxide Synthase.
Yan X, Zhang QY, Zhang YL, Han X, Guo SB, Li HH
Frontiers in pharmacology 2020;11:1121
Frontiers in pharmacology 2020;11:1121
Metformin Mitigates Cartilage Degradation by Activating AMPK/SIRT1-Mediated Autophagy in a Mouse Osteoarthritis Model.
Wang C, Yao Z, Zhang Y, Yang Y, Liu J, Shi Y, Zhang C
Frontiers in pharmacology 2020;11:1114
Frontiers in pharmacology 2020;11:1114
AKT Inhibitor SC66 Inhibits Proliferation and Induces Apoptosis in Human Glioblastoma Through Down-Regulating AKT/β-Catenin Pathway.
Gao L, Liu J, Xu P, Deng G, Liu B, Yuan F, Tan Y, Sun Q, Xu Y, Zhang H, Qi Y, Han S, Yang K, Geng R, Jiang H, Chen Q
Frontiers in pharmacology 2020;11:1102
Frontiers in pharmacology 2020;11:1102
De novo Synthesis of SAA1 in the Placenta Participates in Parturition.
Gan XW, Wang WS, Lu JW, Ling LJ, Zhou Q, Zhang HJ, Ying H, Sun K
Frontiers in immunology 2020;11:1038
Frontiers in immunology 2020;11:1038
MiR-185-5p Protects Against Angiogenesis in Polycystic Ovary Syndrome by Targeting VEGFA.
Wei J, Zhao Y
Frontiers in pharmacology 2020;11:1030
Frontiers in pharmacology 2020;11:1030
Inhibition of JNK-Mediated Autophagy Promotes Proscillaridin A- Induced Apoptosis via ROS Generation, Intracellular Ca+2 Oscillation and Inhibiting STAT3 Signaling in Breast Cancer Cells.
Saleem MZ, Alshwmi M, Zhang H, Din SRU, Nisar MA, Khan M, Alam S, Alam G, Jin L, Ma T
Frontiers in pharmacology 2020;11:01055
Frontiers in pharmacology 2020;11:01055
PAQR4 promotes chemoresistance in non-small cell lung cancer through inhibiting Nrf2 protein degradation.
Xu P, Jiang L, Yang Y, Wu M, Liu B, Shi Y, Shen Q, Jiang X, He Y, Cheng D, Xiong Q, Yang Z, Duan L, Lin J, Zhao S, Shi P, Yang C, Chen Y
Theranostics 2020;10(8):3767-3778
Theranostics 2020;10(8):3767-3778
CNTNAP4 deficiency in dopaminergic neurons initiates parkinsonian phenotypes.
Zhang W, Zhou M, Lu W, Gong J, Gao F, Li Y, Xu X, Lin Y, Zhang X, Ding L, Zhang Z, Li G, Chen X, Sun X, Zhu X, Xu P, Zhang Y
Theranostics 2020;10(7):3000-3021
Theranostics 2020;10(7):3000-3021
SMYD2 suppresses APC2 expression to activate the Wnt/β-catenin pathway and promotes epithelial-mesenchymal transition in colorectal cancer.
Meng F, Liu X, Lin C, Xu L, Liu J, Zhang P, Zhang X, Song J, Yan Y, Ren Z, Zhang Y
American journal of cancer research 2020;10(3):997-1011
American journal of cancer research 2020;10(3):997-1011
Fasudil Promotes α-Synuclein Clearance in an AAV-Mediated α-Synuclein Rat Model of Parkinson's Disease by Autophagy Activation.
Yang YJ, Bu LL, Shen C, Ge JJ, He SJ, Yu HL, Tang YL, Jue Z, Sun YM, Yu WB, Zuo CT, Wu JJ, Wang J, Liu FT
Journal of Parkinson's disease 2020;10(3):969-979
Journal of Parkinson's disease 2020;10(3):969-979
Denervation drives skeletal muscle atrophy and induces mitochondrial dysfunction, mitophagy and apoptosis via miR-142a-5p/MFN1 axis.
Yang X, Xue P, Chen H, Yuan M, Kang Y, Duscher D, Machens HG, Chen Z
Theranostics 2020;10(3):1415-1432
Theranostics 2020;10(3):1415-1432
Promotion of mitochondrial fusion protects against developmental PBDE-47 neurotoxicity by restoring mitochondrial homeostasis and suppressing excessive apoptosis.
Dong L, Li P, Yang K, Liu L, Gao H, Zhou G, Zhao Q, Xia T, Wang A, Zhang S
Theranostics 2020;10(3):1245-1261
Theranostics 2020;10(3):1245-1261
Virus-induced p38 MAPK activation facilitates viral infection.
Cheng Y, Sun F, Wang L, Gao M, Xie Y, Sun Y, Liu H, Yuan Y, Yi W, Huang Z, Yan H, Peng K, Wu Y, Cao Z
Theranostics 2020;10(26):12223-12240
Theranostics 2020;10(26):12223-12240
Restoring the epigenetically silenced PCK2 suppresses renal cell carcinoma progression and increases sensitivity to sunitinib by promoting endoplasmic reticulum stress.
Xiong Z, Yuan C, Shi J, Xiong W, Huang Y, Xiao W, Yang H, Chen K, Zhang X
Theranostics 2020;10(25):11444-11461
Theranostics 2020;10(25):11444-11461
TSTA3 facilitates esophageal squamous cell carcinoma progression through regulating fucosylation of LAMP2 and ERBB2.
Zhang L, Gao Y, Zhang X, Guo M, Yang J, Cui H, Kong P, Niu X, Bi Y, Xu J, Yan T, Ma Y, Yang J, Qian Y, Wang F, Li H, Liu F, Cheng X, Cui Y
Theranostics 2020;10(24):11339-11358
Theranostics 2020;10(24):11339-11358
Truncated HDAC9 identified by integrated genome-wide screen as the key modulator for paclitaxel resistance in triple-negative breast cancer.
Lian B, Pei YC, Jiang YZ, Xue MZ, Li DQ, Li XG, Zheng YZ, Liu XY, Qiao F, Sun WL, Ling H, He M, Yao L, Hu X, Shao ZM
Theranostics 2020;10(24):11092-11109
Theranostics 2020;10(24):11092-11109
Hypergastrinemia Expands Gastric ECL Cells Through CCK2R+ Progenitor Cells via ERK Activation.
Sheng W, Malagola E, Nienhüser H, Zhang Z, Kim W, Zamechek L, Sepulveda A, Hata M, Hayakawa Y, Zhao CM, Chen D, Wang TC
Cellular and molecular gastroenterology and hepatology 2020;10(2):434-449.e1
Cellular and molecular gastroenterology and hepatology 2020;10(2):434-449.e1
LncRNA CSMD1-1 promotes the progression of Hepatocellular Carcinoma by activating MYC signaling.
Liu J, Xu R, Mai SJ, Ma YS, Zhang MY, Cao PS, Weng NQ, Wang RQ, Cao D, Wei W, Guo RP, Zhang YJ, Xu L, Chen MS, Zhang HZ, Huang L, Fu D, Wang HY
Theranostics 2020;10(17):7527-7544
Theranostics 2020;10(17):7527-7544
Protein acetylation derepresses Serotonin Synthesis to potentiate Pancreatic Beta-Cell Function through HDAC1-PKA-Tph1 signaling.
Zhang Y, Wang S, Zhang L, Zhou F, Zhu K, Zhu Q, Liu Q, Liu Y, Jiang L, Ning G, Bi Y, Zhou L, Wang X
Theranostics 2020;10(16):7351-7368
Theranostics 2020;10(16):7351-7368
Diethyldithiocarbamate-copper nanocomplex reinforces disulfiram chemotherapeutic efficacy through light-triggered nuclear targeting.
Ren L, Feng W, Shao J, Ma J, Xu M, Zhu BZ, Zheng N, Liu S
Theranostics 2020;10(14):6384-6398
Theranostics 2020;10(14):6384-6398
Selective targeting of the oncogenic KRAS G12S mutant allele by CRISPR/Cas9 induces efficient tumor regression.
Gao Q, Ouyang W, Kang B, Han X, Xiong Y, Ding R, Li Y, Wang F, Huang L, Chen L, Wang D, Dong X, Zhang Z, Li Y, Ze B, Hou Y, Yang H, Ma Y, Gu Y, Chao CC
Theranostics 2020;10(11):5137-5153
Theranostics 2020;10(11):5137-5153
Circ-EEF2 facilitated autophagy via interaction with mir-6881-3p and ANXA2 in EOC.
Yong M, Hu J, Zhu H, Jiang X, Gan X, Hu L
American journal of cancer research 2020;10(11):3737-3751
American journal of cancer research 2020;10(11):3737-3751
LncRNA NEAT1 facilitates pancreatic cancer growth and metastasis through stabilizing ELF3 mRNA.
Feng Y, Gao L, Cui G, Cao Y
American journal of cancer research 2020;10(1):237-248
American journal of cancer research 2020;10(1):237-248
Ovary Proteome Analysis Reveals RH36 Regulates Reproduction via Vitellin Uptake Mediated by HSP70 Protein in Hard Ticks.
Wang F, Wang Y, Wang G, Zhang H, Kuang C, Zhou Y, Cao J, Zhou J
Frontiers in cellular and infection microbiology 2020;10:93
Frontiers in cellular and infection microbiology 2020;10:93
KLF13 suppresses the proliferation and growth of colorectal cancer cells through transcriptionally inhibiting HMGCS1-mediated cholesterol biosynthesis.
Yao W, Jiao Y, Zhou Y, Luo X
Cell & bioscience 2020;10:76
Cell & bioscience 2020;10:76
RAC1 Involves in the Radioresistance by Mediating Epithelial-Mesenchymal Transition in Lung Cancer.
Tan S, Yi P, Wang H, Xia L, Han Y, Wang H, Zeng B, Tang L, Pan Q, Tian Y, Rao S, Oyang L, Liang J, Lin J, Su M, Shi Y, Liao Q, Zhou Y
Frontiers in oncology 2020;10:649
Frontiers in oncology 2020;10:649
Long Noncoding RNA UCA1 Is Related to Autophagy and Apoptosis in Endometrial Stromal Cells.
Jiang L, Wan Y, Feng Z, Liu D, Ouyang L, Li Y, Liu K
Frontiers in oncology 2020;10:618472
Frontiers in oncology 2020;10:618472
circ_NOTCH3 Functions as a Protooncogene Competing With miR-205-5p, Modulating KLF12 Expression and Promoting the Development and Progression of Basal-Like Breast Carcinoma.
Guan B, Li Q, Zhang HZ, Yang HS
Frontiers in oncology 2020;10:602694
Frontiers in oncology 2020;10:602694
MLK3 Is Associated With Poor Prognosis in Patients With Glioblastomas and Actin Cytoskeleton Remodeling in Glioblastoma Cells.
Zhu Y, Sun JM, Sun ZC, Chen FJ, Wu YP, Hou XY
Frontiers in oncology 2020;10:600762
Frontiers in oncology 2020;10:600762
Antioxidant Effect of Propofol in Gliomas and Its Association With Divalent Metal Transporter 1.
Yang C, Xia Z, Li T, Chen Y, Zhao M, Sun Y, Ma J, Wu Y, Wang X, Wang P, Wang H
Frontiers in oncology 2020;10:590931
Frontiers in oncology 2020;10:590931
Characterization of ROS Metabolic Equilibrium Reclassifies Pan-Cancer Samples and Guides Pathway Targeting Therapy.
Shen S, Yan Z, Wu J, Liu X, Guan G, Zou C, Guo Q, Zhu C, Liu T, Chen C, Chen L, Cheng P, Cheng W, Wu A
Frontiers in oncology 2020;10:581197
Frontiers in oncology 2020;10:581197
Long Non-Coding RNA LINC02747 Promotes the Proliferation of Clear Cell Renal Cell Carcinoma by Inhibiting miR-608 and Activating TFE3.
Ju X, Sun Y, Zhang F, Wei X, Wang Z, He X
Frontiers in oncology 2020;10:573789
Frontiers in oncology 2020;10:573789
PUF60/AURKA Axis Contributes to Tumor Progression and Malignant Phenotypes in Bladder Cancer.
Long Q, An X, Chen M, Wang N, Sui S, Li Y, Zhang C, Lee K, Wang X, Tian T, Pan Y, Qiu H, Xie F, Deng W, Zheng F, He L
Frontiers in oncology 2020;10:568015
Frontiers in oncology 2020;10:568015
Vitamin D3 Inhibits Helicobacter pylori Infection by Activating the VitD3/VDR-CAMP Pathway in Mice.
Zhou A, Li L, Zhao G, Min L, Liu S, Zhu S, Guo Q, Liu C, Zhang S, Li P
Frontiers in cellular and infection microbiology 2020;10:566730
Frontiers in cellular and infection microbiology 2020;10:566730
Single-Cell Sequencing of Glioblastoma Reveals Central Nervous System Susceptibility to SARS-CoV-2.
Wu B, Wang W, Wang H, Zou Q, Hu B, Ye L, Hu Y, Xie Y, Huang N, Lan Q, Cheng H, Dong J, Dai X
Frontiers in oncology 2020;10:566599
Frontiers in oncology 2020;10:566599
BYSL Promotes Glioblastoma Cell Migration, Invasion, and Mesenchymal Transition Through the GSK-3β/β-Catenin Signaling Pathway.
Sha Z, Zhou J, Wu Y, Zhang T, Li C, Meng Q, Musunuru PP, You F, Wu Y, Yu R, Gao S
Frontiers in oncology 2020;10:565225
Frontiers in oncology 2020;10:565225
TDO2 Promotes the EMT of Hepatocellular Carcinoma Through Kyn-AhR Pathway.
Li L, Wang T, Li S, Chen Z, Wu J, Cao W, Wo Q, Qin X, Xu J
Frontiers in oncology 2020;10:562823
Frontiers in oncology 2020;10:562823
Carbohydrate Sulfotransferase 4 Inhibits the Progression of Hepatitis B Virus-Related Hepatocellular Carcinoma and Is a Potential Prognostic Marker in Several Tumors.
Zhang L, Fan Y, Wang X, Yang M, Wu X, Huang W, Lan J, Liao L, Huang W, Yuan L, Pan H, Wu Y, Chen L, Guan J
Frontiers in oncology 2020;10:554331
Frontiers in oncology 2020;10:554331
FOXK1 Promotes Proliferation and Metastasis of Gallbladder Cancer by Activating AKT/mTOR Signaling Pathway.
Wencong M, Jinghan W, Yong Y, Jianyang A, Bin L, Qingbao C, Chen L, Xiaoqing J
Frontiers in oncology 2020;10:545
Frontiers in oncology 2020;10:545
Thioguanine Induces Apoptosis in Triple-Negative Breast Cancer by Regulating PI3K-AKT Pathway.
Zhang D, An X, Li Q, Man X, Chu M, Li H, Zhang N, Dai X, Yu H, Li Z
Frontiers in oncology 2020;10:524922
Frontiers in oncology 2020;10:524922
Long Non-coding RNA CCAT1 Acts as an Oncogene and Promotes Sunitinib Resistance in Renal Cell Carcinoma.
Shan L, Liu W, Zhan Y
Frontiers in oncology 2020;10:516552
Frontiers in oncology 2020;10:516552
CDC27 Promotes Tumor Progression and Affects PD-L1 Expression in T-Cell Lymphoblastic Lymphoma.
Song Y, Song W, Li Z, Song W, Wen Y, Li J, Xia Q, Zhang M
Frontiers in oncology 2020;10:488
Frontiers in oncology 2020;10:488
Nicotine Reduces Human Brain Microvascular Endothelial Cell Response to Escherichia coli K1 Infection by Inhibiting Autophagy.
Wu C, Yang M, Liu R, Hu H, Ji L, Zhang X, Huang S, Wang L
Frontiers in cellular and infection microbiology 2020;10:484
Frontiers in cellular and infection microbiology 2020;10:484
Nevirapine Increases Sodium/Iodide Symporter-Mediated Radioiodide Uptake by Activation of TSHR/cAMP/CREB/PAX8 Signaling Pathway in Dedifferentiated Thyroid Cancer.
Shang H, Zhao J, Yao J, Wang H, Dong J, Liao L
Frontiers in oncology 2020;10:404
Frontiers in oncology 2020;10:404
EGFR/FOXO3A/LXR-α Axis Promotes Prostate Cancer Proliferation and Metastasis and Dual-Targeting LXR-α/EGFR Shows Synthetic Lethality.
Chen T, Xu J, Fu W
Frontiers in oncology 2020;10:1688
Frontiers in oncology 2020;10:1688
miR-15b-5p Promotes Growth and Metastasis in Breast Cancer by Targeting HPSE2.
Wu B, Liu G, Jin Y, Yang T, Zhang D, Ding L, Zhou F, Pan Y, Wei Y
Frontiers in oncology 2020;10:108
Frontiers in oncology 2020;10:108
Conditional ablation of MAPK7 expression in chondrocytes impairs endochondral bone formation in limbs and adaptation of chondrocytes to hypoxia.
Yang X, Zhong D, Gao W, Liao Z, Chen Y, Zhang S, Zhou H, Su P, Xu C
Cell & bioscience 2020;10:103
Cell & bioscience 2020;10:103
The neuro-immune interaction in airway inflammation through TRPA1 expression in CD4+ T cells of asthmatic mice.
Li M, Fan X, Yue Q, Hu F, Zhang Y, Zhu C
International immunopharmacology 2020 Sep;86:106696
International immunopharmacology 2020 Sep;86:106696
Curcumin ameliorates CKD-induced mitochondrial dysfunction and oxidative stress through inhibiting GSK-3β activity.
Wang D, Yang Y, Zou X, Zheng Z, Zhang J
The Journal of nutritional biochemistry 2020 Sep;83:108404
The Journal of nutritional biochemistry 2020 Sep;83:108404
Resveratrol inhibits the tumor migration and invasion by upregulating TET1 and reducing TIMP2/3 methylation in prostate carcinoma cells.
Wang K, Chen Z, Shi J, Feng Y, Yu M, Sun Y, Zhuang Q, Liang B, Luo G, Xu X, Fan M
The Prostate 2020 Sep;80(12):977-985
The Prostate 2020 Sep;80(12):977-985
METTL7B (methyltransferase-like 7B) identification as a novel biomarker for lung adenocarcinoma.
Ali J, Liu W, Duan W, Liu C, Song J, Ali S, Li E, Wang Q
Annals of translational medicine 2020 Sep;8(18):1130
Annals of translational medicine 2020 Sep;8(18):1130
Magnolol inhibits myotube atrophy induced by cancer cachexia through myostatin signaling pathway in vitro.
Ge Z, Liu D, Shang Y, Li Y, Chen SZ
Journal of natural medicines 2020 Sep;74(4):741-749
Journal of natural medicines 2020 Sep;74(4):741-749
Bisphenol-A exposure induced neurotoxicity and associated with synapse and cytoskeleton in Neuro-2a cells.
Yin Z, Hua L, Chen L, Hu D, Li J, An Z, Tian T, Ning H, Ge Y
Toxicology in vitro : an international journal published in association with BIBRA 2020 Sep;67:104911
Toxicology in vitro : an international journal published in association with BIBRA 2020 Sep;67:104911
Islet-cell autoantigen 69 accelerates liver regeneration by downregulating Tgfbr1 and attenuating Tgfβ signaling in mice.
Chen L, Tao F, Zhang Y, Shu C, Xiang W, Yang L, Chen X, Hong Y, Chen B, Li K, Zhang W, Hao K, Ge F, Wang Z, Lyu J
FEBS letters 2020 Sep;594(17):2881-2893
FEBS letters 2020 Sep;594(17):2881-2893
GBP1 promotes erlotinib resistance via PGK1‑activated EMT signaling in non‑small cell lung cancer.
Cheng L, Gou L, Wei T, Zhang J
International journal of oncology 2020 Sep;57(3):858-870
International journal of oncology 2020 Sep;57(3):858-870
ID1 overexpression promotes HCC progression by amplifying the AURKA/Myc signaling pathway.
Wu M, Zhou Y, Fei C, Chen T, Yin X, Zhang L, Ren Z
International journal of oncology 2020 Sep;57(3):845-857
International journal of oncology 2020 Sep;57(3):845-857
Protein phosphorylation profiling of peripheral nerve regeneration after autologous nerve grafting.
Cheng Z, Shen Y, Qian T, Yi S, He J
Molecular and cellular biochemistry 2020 Sep;472(1-2):35-44
Molecular and cellular biochemistry 2020 Sep;472(1-2):35-44
High glucose condition inhibits trophoblast proliferation, migration and invasion by downregulating placental growth factor expression.
Tao J, Xia LZ, Chen JJ, Zeng JF, Meng J, Wu S, Wang Z
The journal of obstetrics and gynaecology research 2020 Sep;46(9):1690-1701
The journal of obstetrics and gynaecology research 2020 Sep;46(9):1690-1701
Sodium Butyrate Exacerbates Parkinson's Disease by Aggravating Neuroinflammation and Colonic Inflammation in MPTP-Induced Mice Model.
Qiao CM, Sun MF, Jia XB, Li Y, Zhang BP, Zhao LP, Shi Y, Zhou ZL, Zhu YL, Cui C, Shen YQ
Neurochemical research 2020 Sep;45(9):2128-2142
Neurochemical research 2020 Sep;45(9):2128-2142
A Novel Compound YS-5-23 Exhibits Neuroprotective Effect by Reducing β-Site Amyloid Precursor Protein Cleaving Enzyme 1's Expression and H2O2-Induced Cytotoxicity in SH-SY5Y Cells.
Cheng C, Zheng N, Sun D, Fang W, Zheng L, Song W, Huang J
Neurochemical research 2020 Sep;45(9):2113-2127
Neurochemical research 2020 Sep;45(9):2113-2127
ErbB4 knockdown in serotonergic neurons in the dorsal raphe induces anxiety-like behaviors.
Zhang SR, Wu JL, Chen H, Luo R, Chen WJ, Tang LJ, Li XW, Yang JM, Gao TM
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2020 Sep;45(10):1698-1706
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2020 Sep;45(10):1698-1706
Differential regulation of Actn2 and Actn3 expression during unfolded protein response in C2C12 myotubes.
Harada N, Gotoda Y, Hatakeyama A, Nakagawa T, Miyatake Y, Kuroda M, Masumoto S, Tsutsumi R, Nakaya Y, Sakaue H
Journal of muscle research and cell motility 2020 Sep;41(2-3):199-209
Journal of muscle research and cell motility 2020 Sep;41(2-3):199-209
Mitochondrial superoxide contributes to oxidative stress exacerbated by DNA damage response in RAD51-depleted ovarian cancer cells.
Xu L, Wu T, Lu S, Hao X, Qin J, Wang J, Zhang X, Liu Q, Kong B, Gong Y, Liu Z, Shao C
Redox biology 2020 Sep;36:101604
Redox biology 2020 Sep;36:101604
Obesity promotes gastric cancer metastasis via diacylglycerol acyltransferase 2-dependent lipid droplets accumulation and redox homeostasis.
Li S, Wu T, Lu YX, Wang JX, Yu FH, Yang MZ, Huang YJ, Li ZJ, Wang SL, Huang L, Lu L, Tian T
Redox biology 2020 Sep;36:101596
Redox biology 2020 Sep;36:101596
Vagus Nerve Stimulation Attenuates Early Traumatic Brain Injury by Regulating the NF-κB/NLRP3 Signaling Pathway.
Tang Y, Dong X, Chen G, Ye W, Kang J, Tang Y, Feng Z
Neurorehabilitation and neural repair 2020 Sep;34(9):831-843
Neurorehabilitation and neural repair 2020 Sep;34(9):831-843
APC2CDH1 negatively regulates agrin signaling by promoting the ubiquitination and proteolytic degradation of DOK7.
Chen A, Bai L, Zhong K, Shu X, Wang A, Xiao Y, Zhang K, Shen C
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Sep;34(9):12009-12023
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Sep;34(9):12009-12023
Selenoprotein T protects against cisplatin-induced acute kidney injury through suppression of oxidative stress and apoptosis.
Huang J, Bao D, Lei CT, Tang H, Zhang CY, Su H, Zhang C
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Sep;34(9):11983-11996
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Sep;34(9):11983-11996
The MAF1 Phosphoregulatory Region Controls MAF1 Interaction with the RNA Polymerase III C34 Subunit and Transcriptional Repression in Plants.
Oliveira Andrade M, Sforça ML, Batista FAH, Figueira ACM, Benedetti CE
The Plant cell 2020 Sep;32(9):3019-3035
The Plant cell 2020 Sep;32(9):3019-3035
A paralog-specific role of COPI vesicles in the neuronal differentiation of mouse pluripotent cells.
Jain Goyal M, Zhao X, Bozhinova M, Andrade-López K, de Heus C, Schulze-Dramac S, Müller-McNicoll M, Klumperman J, Béthune J
Life science alliance 2020 Sep;3(9)
Life science alliance 2020 Sep;3(9)
The deubiquitylase USP2 maintains ErbB2 abundance via counteracting endocytic degradation and represents a therapeutic target in ErbB2-positive breast cancer.
Zhang J, Liu S, Li Q, Shi Y, Wu Y, Liu F, Wang S, Zaky MY, Yousuf W, Sun Q, Guo D, Wang T, Zhang Y, Wang Y, Li M, Liu H
Cell death and differentiation 2020 Sep;27(9):2710-2725
Cell death and differentiation 2020 Sep;27(9):2710-2725
Cardioprotection by isosteviol derivate JC105: A unique drug property to activate ERK1/2 only when cells are exposed to hypoxia-reoxygenation.
Mohammed Abdul KS, Rayadurgam J, Faiz N, Jovanović A, Tan W
Journal of cellular and molecular medicine 2020 Sep;24(18):10924-10934
Journal of cellular and molecular medicine 2020 Sep;24(18):10924-10934
Decreased ANGPTL4 impairs endometrial angiogenesis during peri-implantation period in patients with recurrent implantation failure.
Li M, Hu J, Yao L, Gao M
Journal of cellular and molecular medicine 2020 Sep;24(18):10730-10743
Journal of cellular and molecular medicine 2020 Sep;24(18):10730-10743
Follicle-stimulating hormone impairs dental pulp stem cells odontogenic differentiation.
Qian H, Guan X
Journal of cellular and molecular medicine 2020 Sep;24(18):10621-10635
Journal of cellular and molecular medicine 2020 Sep;24(18):10621-10635
Musashi2 promotes the progression of pancreatic cancer through a novel ISYNA1-p21/ZEB-1 pathway.
Zhou L, Sheng W, Jia C, Shi X, Cao R, Wang G, Lin Y, Zhu F, Dong Q, Dong M
Journal of cellular and molecular medicine 2020 Sep;24(18):10560-10572
Journal of cellular and molecular medicine 2020 Sep;24(18):10560-10572
AKR1C2 acts as a targetable oncogene in esophageal squamous cell carcinoma via activating PI3K/AKT signaling pathway.
Zhang ZF, Huang TJ, Zhang XK, Xie YJ, Lin ST, Luo FF, Meng DF, Hu H, Wang J, Peng LX, Qian CN, Cheng C, Huang BJ
Journal of cellular and molecular medicine 2020 Sep;24(17):9999-10012
Journal of cellular and molecular medicine 2020 Sep;24(17):9999-10012
Aberrant ASPM expression mediated by transcriptional regulation of FoxM1 promotes the progression of gliomas.
Zeng WJ, Cheng Q, Wen ZP, Wang JY, Chen YH, Zhao J, Gong ZC, Chen XP
Journal of cellular and molecular medicine 2020 Sep;24(17):9613-9626
Journal of cellular and molecular medicine 2020 Sep;24(17):9613-9626
UVA influenced the SIRT1-miR-27a-5p-SMAD2-MMP1/COL1/BCL2 axis in human skin primary fibroblasts.
Jiang SB, Lu YS, Liu T, Li LM, Wang HX, Wu Y, Gao XH, Chen HD
Journal of cellular and molecular medicine 2020 Sep;24(17):10027-10041
Journal of cellular and molecular medicine 2020 Sep;24(17):10027-10041
Deubiquitinase USP13 promotes extracellular matrix expression by stabilizing Smad4 in lung fibroblast cells.
Liao X, Li Y, Liu J, Zhang Y, Tan J, Kass DJ, Rojas M, Mallampalli RK, Zhao J, Zhao Y
Translational research : the journal of laboratory and clinical medicine 2020 Sep;223:15-24
Translational research : the journal of laboratory and clinical medicine 2020 Sep;223:15-24
TRIM11 promotes breast cancer cell proliferation by stabilizing estrogen receptor α.
Tang J, Luo Y, Tian Z, Liao X, Cui Q, Yang Q, Wu G
Neoplasia (New York, N.Y.) 2020 Sep;22(9):343-351
Neoplasia (New York, N.Y.) 2020 Sep;22(9):343-351
Circular RNA hsa_circ_0005556 Accelerates Gastric Cancer Progression by Sponging miR-4270 to Increase MMP19 Expression.
Shen D, Zhao H, Zeng P, Song J, Yang Y, Gu X, Ji Q, Zhao W
Journal of gastric cancer 2020 Sep;20(3):300-312
Journal of gastric cancer 2020 Sep;20(3):300-312
Antiviral immune mechanism of Toll-like receptor 4-mediated human alveolar epithelial cells type Ⅱ.
Wang D, Wang J
Experimental and therapeutic medicine 2020 Sep;20(3):2561-2568
Experimental and therapeutic medicine 2020 Sep;20(3):2561-2568
Oxidation of multiple MiT/TFE transcription factors links oxidative stress to transcriptional control of autophagy and lysosome biogenesis.
Wang H, Wang N, Xu D, Ma Q, Chen Y, Xu S, Xia Q, Zhang Y, Prehn JHM, Wang G, Ying Z
Autophagy 2020 Sep;16(9):1683-1696
Autophagy 2020 Sep;16(9):1683-1696
Myeloid Cell Expression of LACC1 Is Required for Bacterial Clearance and Control of Intestinal Inflammation.
Kang JW, Yan J, Ranjan K, Zhang X, Turner JR, Abraham C
Gastroenterology 2020 Sep;159(3):1051-1067
Gastroenterology 2020 Sep;159(3):1051-1067
BAIAP2L2 promotes the progression of gastric cancer via AKT/mTOR and Wnt3a/β-catenin signaling pathways.
Liu J, Shangguan Y, Sun J, Cong W, Xie Y
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Sep;129:110414
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Sep;129:110414
PM2.5 compromises antiviral immunity in influenza infection by inhibiting activation of NLRP3 inflammasome and expression of interferon-β.
Tao RJ, Cao WJ, Li MH, Yang L, Dai RX, Luo XL, Liu Y, Ge BX, Su X, Xu JF
Molecular immunology 2020 Sep;125:178-186
Molecular immunology 2020 Sep;125:178-186
Novel long non-coding RNA LINC02323 promotes epithelial-mesenchymal transition and metastasis via sponging miR-1343-3p in lung adenocarcinoma.
Zhang X, Du L, Han J, Li X, Wang H, Zheng G, Wang Y, Yang Y, Hu Y, Wang C
Thoracic cancer 2020 Sep;11(9):2506-2516
Thoracic cancer 2020 Sep;11(9):2506-2516
Icariside Ⅱ, a main compound in Epimedii Folium, induces idiosyncratic hepatotoxicity by enhancing NLRP3 inflammasome activation.
Wang Z, Xu G, Wang H, Zhan X, Gao Y, Chen N, Li R, Song X, Guo Y, Yang R, Niu M, Wang J, Liu Y, Xiao X, Bai Z
Acta pharmaceutica Sinica. B 2020 Sep;10(9):1619-1633
Acta pharmaceutica Sinica. B 2020 Sep;10(9):1619-1633
Impaired NHEJ repair in amyotrophic lateral sclerosis is associated with TDP-43 mutations.
Konopka A, Whelan DR, Jamali MS, Perri E, Shahheydari H, Toth RP, Parakh S, Robinson T, Cheong A, Mehta P, Vidal M, Ragagnin AMG, Khizhnyak I, Jagaraj CJ, Galper J, Grima N, Deva A, Shadfar S, Nicholson GA, Yang S, Cutts SM, Horejsi Z, Bell TDM, Walker AK, Blair IP, Atkin JD
Molecular neurodegeneration 2020 Sep 9;15(1):51
Molecular neurodegeneration 2020 Sep 9;15(1):51
Functional regulation of an ancestral RAG transposon ProtoRAG by a trans-acting factor YY1 in lancelet.
Liu S, Yuan S, Gao X, Tao X, Yu W, Li X, Chen S, Xu A
Nature communications 2020 Sep 9;11(1):4515
Nature communications 2020 Sep 9;11(1):4515
Legionella Manipulates Non-canonical SNARE Pairing Using a Bacterial Deubiquitinase.
Kitao T, Taguchi K, Seto S, Arasaki K, Ando H, Nagai H, Kubori T
Cell reports 2020 Sep 8;32(10):108107
Cell reports 2020 Sep 8;32(10):108107
MiR-126 Regulates Properties of SOX9+ Liver Progenitor Cells during Liver Repair by Targeting Hoxb6.
Yan Y, Wang R, Hu X, Wang S, Zhang L, Hou C, Zhang L
Stem cell reports 2020 Sep 8;15(3):706-720
Stem cell reports 2020 Sep 8;15(3):706-720
Knockdown of TXNDC9 induces apoptosis and autophagy in glioma and mediates cell differentiation by p53 activation.
Zheng T, Chen K, Zhang X, Feng H, Shi Y, Liu L, Zhang J, Chen Y
Aging 2020 Sep 8;12(18):18649-18659
Aging 2020 Sep 8;12(18):18649-18659
Autocrine INSL5 promotes tumor progression and glycolysis via activation of STAT5 signaling.
Li SB, Liu YY, Yuan L, Ji MF, Zhang A, Li HY, Tang LQ, Fang SG, Zhang H, Xing S, Li MZ, Zhong Q, Lin SJ, Liu WL, Huang P, Zeng YX, Zheng YM, Ling ZQ, Sui JH, Zeng MS
EMBO molecular medicine 2020 Sep 7;12(9):e12050
EMBO molecular medicine 2020 Sep 7;12(9):e12050
hUMSCs regulate the differentiation of ovarian stromal cells via TGF-β1/Smad3 signaling pathway to inhibit ovarian fibrosis to repair ovarian function in POI rats.
Cui L, Bao H, Liu Z, Man X, Liu H, Hou Y, Luo Q, Wang S, Fu Q, Zhang H
Stem cell research & therapy 2020 Sep 7;11(1):386
Stem cell research & therapy 2020 Sep 7;11(1):386
Palmatine ameliorates Helicobacter pylori-induced chronic atrophic gastritis by inhibiting MMP-10 through ADAM17/EGFR.
Chen X, Wang R, Bao C, Zhang J, Zhang J, Li R, Wu S, Wen J, Yang T, Wei S, Li H, Wei Y, Ren S, Zhao Y
European journal of pharmacology 2020 Sep 5;882:173267
European journal of pharmacology 2020 Sep 5;882:173267
Long non-coding RNA FAM133B-2 represses the radio-resistance of nasopharyngeal cancer cells by targeting miR-34a-5p/CDK6 axis.
Huang D, Zhu X, Wang Y, Yu H, Pu Y
Aging 2020 Sep 5;12(17):16936-16950
Aging 2020 Sep 5;12(17):16936-16950
Neuroprotective Effect of Piracetam against Cocaine-Induced Neuro Epigenetic Modification of DNA Methylation in Astrocytes.
Sivalingam K, Samikkannu T
Brain sciences 2020 Sep 5;10(9)
Brain sciences 2020 Sep 5;10(9)
Aristolochic acid I promotes the invasion and migration of hepatocellular carcinoma cells by activating the C3a/C3aR complement system.
Li Y, Zhu S, Xue M, Jing Y, Liu X, Cai D, Zhao Y, Bian Y, Zhang Z, Zhang L
Toxicology letters 2020 Sep 5;
Toxicology letters 2020 Sep 5;
YAP1 Inhibition in HUVECs Is Associated with Released Exosomes and Increased Hepatocarcinoma Invasion and Metastasis.
Li Y, Zhang X, Zheng Q, Zhang Y, Ma Y, Zhu C, Yang L, Peng X, Wang Q, Wang B, Meng X, Li H, Liu J
Molecular therapy. Nucleic acids 2020 Sep 4;21:86-97
Molecular therapy. Nucleic acids 2020 Sep 4;21:86-97
Circular RNA circREPS2 Acts as a Sponge of miR-558 to Suppress Gastric Cancer Progression by Regulating RUNX3/β-catenin Signaling.
Guo X, Dai X, Liu J, Cheng A, Qin C, Wang Z
Molecular therapy. Nucleic acids 2020 Sep 4;21:577-591
Molecular therapy. Nucleic acids 2020 Sep 4;21:577-591
Fc-Elabela fusion protein attenuates lipopolysaccharide-induced kidney injury in mice.
Xu F, Zhou H, Wu M, Zhang H, Zhang Y, Zhao Q, Brown R, Gong DW, Miao L
Bioscience reports 2020 Sep 30;40(9)
Bioscience reports 2020 Sep 30;40(9)
Porphyromonas gingivalis disrupts vascular endothelial homeostasis in a TLR-NF-κB axis dependent manner.
Xie M, Tang Q, Yu S, Sun J, Mei F, Zhao J, Chen L
International journal of oral science 2020 Sep 30;12(1):28
International journal of oral science 2020 Sep 30;12(1):28
Anti-bacterial and anti-viral nanchangmycin displays anti-myeloma activity by targeting Otub1 and c-Maf.
Xu Y, Sun T, Zeng K, Xu M, Chen J, Xu X, Zhang Z, Cao B, Tang X, Wu D, Kong Y, Zeng Y, Mao X
Cell death & disease 2020 Sep 30;11(9):818
Cell death & disease 2020 Sep 30;11(9):818
Quality Control of ER Membrane Proteins by the RNF185/Membralin Ubiquitin Ligase Complex.
van de Weijer ML, Krshnan L, Liberatori S, Guerrero EN, Robson-Tull J, Hahn L, Lebbink RJ, Wiertz EJHJ, Fischer R, Ebner D, Carvalho P
Molecular cell 2020 Sep 3;79(5):768-781.e7
Molecular cell 2020 Sep 3;79(5):768-781.e7
Aldehyde dehydrogenase 2 inhibited oxidized LDL-induced NLRP3 inflammasome priming and activation via attenuating oxidative stress.
Xu Y, Yuan Q, Cao S, Cui S, Xue L, Song X, Li Z, Xu R, Yuan Q, Li R
Biochemical and biophysical research communications 2020 Sep 3;529(4):998-1004
Biochemical and biophysical research communications 2020 Sep 3;529(4):998-1004
KLF16 overexpression deleteriously affects the proliferation and migration of retinoblastoma by transcriptionally repressing BCL2L15.
Zhang JX, Yan XJ, Wu S, Liu Q, Ma JM
Biochemical and biophysical research communications 2020 Sep 3;529(4):977-983
Biochemical and biophysical research communications 2020 Sep 3;529(4):977-983
BAP1 regulates AMPK-mTOR signalling pathway through deubiquitinating and stabilizing tumour-suppressor LKB1.
Yang C, Ding H, Yang Y, Yang L, Yang Y, Fang M, Ren J, Hu R, Wang C, Geng W
Biochemical and biophysical research communications 2020 Sep 3;529(4):1025-1032
Biochemical and biophysical research communications 2020 Sep 3;529(4):1025-1032
The microRNA/TET3/REST axis is required for olfactory globose basal cell proliferation and male behavior.
Yang D, Wu X, Zhou Y, Wang W, Wang Z
EMBO reports 2020 Sep 3;21(9):e49431
EMBO reports 2020 Sep 3;21(9):e49431
TRIM29 inhibits miR-873-5P biogenesis via CYTOR to upregulate fibronectin 1 and promotes invasion of papillary thyroid cancer cells.
Wu T, Zhang DL, Wang JM, Jiang JY, Du X, Zeng XY, Du ZX
Cell death & disease 2020 Sep 29;11(9):813
Cell death & disease 2020 Sep 29;11(9):813
Maternal sevoflurane exposure affects differentiation of hippocampal neural stem cells by regulating miR-410-3p and ATN1.
Zhang Y, Wu Z, Li X, Wan Y, Zhang Y, Zhao P
Stem cell research & therapy 2020 Sep 29;11(1):423
Stem cell research & therapy 2020 Sep 29;11(1):423
Antimicrobial Effect of Zophobas morio Hemolymph against Bovine Mastitis Pathogens.
Du M, Liu X, Xu J, Li S, Wang S, Zhu Y, Wang J
Microorganisms 2020 Sep 28;8(10)
Microorganisms 2020 Sep 28;8(10)
Small-molecule MMP2/MMP9 inhibitor SB-3CT modulates tumor immune surveillance by regulating PD-L1.
Ye Y, Kuang X, Xie Z, Liang L, Zhang Z, Zhang Y, Ma F, Gao Q, Chang R, Lee HH, Zhao S, Su J, Li H, Peng J, Chen H, Yin M, Peng C, Yang N, Wang J, Liu J, Liu H, Han L, Chen X
Genome medicine 2020 Sep 28;12(1):83
Genome medicine 2020 Sep 28;12(1):83
Establishment and characterization of a PCOS and a normal human granulosa cell line.
Hashemian Z, Afsharian P, Farzaneh P, Eftekhari-Yazdi P, Vakhshiteh F, Daneshvar Amoli A, Nasimian A
Cytotechnology 2020 Sep 28;
Cytotechnology 2020 Sep 28;
Multi-Compartment, Early Disruption of cGMP and cAMP Signalling in Cardiac Myocytes from the mdx Model of Duchenne Muscular Dystrophy.
Brescia M, Chao YC, Koschinski A, Tomek J, Zaccolo M
International journal of molecular sciences 2020 Sep 25;21(19)
International journal of molecular sciences 2020 Sep 25;21(19)
Imaging-Based Reporter Systems to Define CVB-Induced Membrane Remodeling in Living Cells.
Lennemann NJ, Evans AS, Coyne CB
Viruses 2020 Sep 25;12(10)
Viruses 2020 Sep 25;12(10)
RNA-binding protein CUGBP1 controls the differential INSR splicing in molecular subtypes of breast cancer cells and affects cell aggressiveness.
Huang G, Song C, Wang N, Qin T, Sui S, Obr A, Zeng L, Wood TL, Leroith D, Li M, Wu Y
Carcinogenesis 2020 Sep 24;41(9):1294-1305
Carcinogenesis 2020 Sep 24;41(9):1294-1305
MSC-derived exosomes promote recovery from traumatic brain injury via microglia/macrophages in rat.
Chen Y, Li J, Ma B, Li N, Wang S, Sun Z, Xue C, Han Q, Wei J, Zhao RC
Aging 2020 Sep 23;12(18):18274-18296
Aging 2020 Sep 23;12(18):18274-18296
Peptidome analysis of umbilical cord mesenchymal stem cell (hUC-MSC) conditioned medium from preterm and term infants.
Wang Y, Zhang L, Wu Y, Zhu R, Wang Y, Cao Y, Long W, Ji C, Wang H, You L
Stem cell research & therapy 2020 Sep 23;11(1):414
Stem cell research & therapy 2020 Sep 23;11(1):414
Bardoxolone conjugation enables targeted protein degradation of BRD4.
Tong B, Luo M, Xie Y, Spradlin JN, Tallarico JA, McKenna JM, Schirle M, Maimone TJ, Nomura DK
Scientific reports 2020 Sep 23;10(1):15543
Scientific reports 2020 Sep 23;10(1):15543
CD36 facilitates fatty acid uptake by dynamic palmitoylation-regulated endocytosis.
Hao JW, Wang J, Guo H, Zhao YY, Sun HH, Li YF, Lai XY, Zhao N, Wang X, Xie C, Hong L, Huang X, Wang HR, Li CB, Liang B, Chen S, Zhao TJ
Nature communications 2020 Sep 21;11(1):4765
Nature communications 2020 Sep 21;11(1):4765
miR-29a Modulates GSK3β/SIRT1-Linked Mitochondrial Proteostatic Stress to Ameliorate Mouse Non-Alcoholic Steatohepatitis.
Yang YL, Wang PW, Wang FS, Lin HY, Huang YH
International journal of molecular sciences 2020 Sep 19;21(18)
International journal of molecular sciences 2020 Sep 19;21(18)
NRF2 preserves genomic integrity by facilitating ATR activation and G2 cell cycle arrest.
Sun X, Wang Y, Ji K, Liu Y, Kong Y, Nie S, Li N, Hao J, Xie Y, Xu C, Du L, Liu Q
Nucleic acids research 2020 Sep 18;48(16):9109-9123
Nucleic acids research 2020 Sep 18;48(16):9109-9123
Complex I mutations synergize to worsen the phenotypic expression of Leber's hereditary optic neuropathy.
Ji Y, Zhang J, Lu Y, Yi Q, Chen M, Xie S, Mao X, Xiao Y, Meng F, Zhang M, Yang R, Guan MX
The Journal of biological chemistry 2020 Sep 18;295(38):13224-13238
The Journal of biological chemistry 2020 Sep 18;295(38):13224-13238
Zinc oxide nanoparticles effectively regulate autophagic cell death by activating autophagosome formation and interfering with their maturation.
Liu Z, Lv X, Xu L, Liu X, Zhu X, Song E, Song Y
Particle and fibre toxicology 2020 Sep 18;17(1):46
Particle and fibre toxicology 2020 Sep 18;17(1):46
Cepharanthine and Curcumin inhibited mitochondrial apoptosis induced by PCV2.
Xu Y, Zheng J, Sun P, Guo J, Zheng X, Sun Y, Fan K, Yin W, Li H, Sun N
BMC veterinary research 2020 Sep 18;16(1):345
BMC veterinary research 2020 Sep 18;16(1):345
Resveratrol alleviates the interleukin-1β-induced chondrocytes injury through the NF-κB signaling pathway.
Yi H, Zhang W, Cui ZM, Cui SY, Fan JB, Zhu XH, Liu W
Journal of orthopaedic surgery and research 2020 Sep 18;15(1):424
Journal of orthopaedic surgery and research 2020 Sep 18;15(1):424
AKT2 regulates development and metabolic homeostasis via AMPK-depedent pathway in skeletal muscle.
Chen M, Ji C, Yang Q, Gao S, Peng Y, Li Z, Gao X, Li Y, Jiang N, Zhang Y, Bian X, Chen C, Zhang K, Sanchis D, Yan F, Ye J
Clinical science (London, England : 1979) 2020 Sep 18;134(17):2381-2398
Clinical science (London, England : 1979) 2020 Sep 18;134(17):2381-2398
Cyclin G2 Is Involved in the Proliferation of Placental Trophoblast Cells and Their Interactions with Endothelial Cells.
Sun M, Liu S, Gao J, Meng T, Xing X, Chen C, Chen H, Luo Y
Medical science monitor : international medical journal of experimental and clinical research 2020 Sep 17;26:e926414
Medical science monitor : international medical journal of experimental and clinical research 2020 Sep 17;26:e926414
Stachydrine hydrochloride suppresses phenylephrine-induced pathological cardiac hypertrophy by inhibiting the calcineurin/nuclear factor of activated T-cell signalling pathway.
Zheng J, Tian J, Wang S, Hu P, Wu Q, Shan X, Zhao P, Zhang C, Guo W, Xu M, Chen H, Lu R
European journal of pharmacology 2020 Sep 15;883:173386
European journal of pharmacology 2020 Sep 15;883:173386
α-Cyperone inhibits the proliferation of human cervical cancer HeLa cells via ROS-mediated PI3K/Akt/mTOR signaling pathway.
Pei XD, Yao HL, Shen LQ, Yang Y, Lu L, Xiao JS, Wang XY, He ZL, Jiang LH
European journal of pharmacology 2020 Sep 15;883:173355
European journal of pharmacology 2020 Sep 15;883:173355
MicroRNA-183 exerts a protective role in lupus nephritis through blunting the activation of TGF-β/Smad/TLR3 pathway via reducing Tgfbr1.
Qi H, Cao Q, Liu Q
Experimental cell research 2020 Sep 15;394(2):112138
Experimental cell research 2020 Sep 15;394(2):112138
The Natural Compound Notopterol Binds and Targets JAK2/3 to Ameliorate Inflammation and Arthritis.
Wang Q, Zhou X, Yang L, Zhao Y, Chew Z, Xiao J, Liu C, Zheng X, Zheng Y, Shi Q, Liang Q, Wang Y, Wang H
Cell reports 2020 Sep 15;32(11):108158
Cell reports 2020 Sep 15;32(11):108158
A tRNA-derived fragment (tRF-3001b) aggravates the development of nonalcoholic fatty liver disease by inhibiting autophagy.
Zhu J, Cheng M, Zhao X
Life sciences 2020 Sep 15;257:118125
Life sciences 2020 Sep 15;257:118125
Inhibition of PP2A enhances the osteogenic differentiation of human aortic valvular interstitial cells via ERK and p38 MAPK pathways.
Xie F, Li F, Li R, Liu Z, Shi J, Zhang C, Dong N
Life sciences 2020 Sep 15;257:118086
Life sciences 2020 Sep 15;257:118086
Paired box 9 regulates VSMC phenotypic transformation, proliferation, and migration via sonic hedgehog.
Xu J, Zhang Y, You S, Guo Y, Chen S, Chang Y, Zhang N, Sun Y
Life sciences 2020 Sep 15;257:118053
Life sciences 2020 Sep 15;257:118053
Melatonin rescues glucocorticoid-induced inhibition of osteoblast differentiation in MC3T3-E1 cells via the PI3K/AKT and BMP/Smad signalling pathways.
Zhao R, Tao L, Qiu S, Shen L, Tian Y, Gong Z, Tao ZB, Zhu Y
Life sciences 2020 Sep 15;257:118044
Life sciences 2020 Sep 15;257:118044
BMSC-derived exosomes alleviate smoke inhalation lung injury through blockade of the HMGB1/NF-κB pathway.
Xu B, Gan CX, Chen SS, Li JQ, Liu MZ, Guo GH
Life sciences 2020 Sep 15;257:118042
Life sciences 2020 Sep 15;257:118042
High fat diet impairs spermatogenesis by regulating glucose and lipid metabolism in Sertoli cells.
Luo D, Zhang M, Su X, Liu L, Zhou X, Zhang X, Zheng D, Yu C, Guan Q
Life sciences 2020 Sep 15;257:118028
Life sciences 2020 Sep 15;257:118028
Sphingomyelin Synthase 2 Participate in the Regulation of Sperm Motility and Apoptosis.
Li X, Luo T, Li H, Yan N
Molecules (Basel, Switzerland) 2020 Sep 15;25(18)
Molecules (Basel, Switzerland) 2020 Sep 15;25(18)
Overactivated sonic hedgehog signaling aggravates intrauterine adhesion via inhibiting autophagy in endometrial stromal cells.
Wei C, Pan Y, Zhang Y, Dai Y, Jiang L, Shi L, Yang W, Xu S, Zhang Y, Xu W, Zhang Y, Lin X, Zhang S
Cell death & disease 2020 Sep 15;11(9):755
Cell death & disease 2020 Sep 15;11(9):755
Troxerutin protects against DHT-induced polycystic ovary syndrome in rats.
Gao Z, Ma X, Liu J, Ge Y, Wang L, Fu P, Liu Z, Yao R, Yan X
Journal of ovarian research 2020 Sep 13;13(1):106
Journal of ovarian research 2020 Sep 13;13(1):106
Tectorigenin enhances PDX1 expression and protects pancreatic β-cells by activating ERK and reducing ER stress.
Yao X, Li K, Liang C, Zhou Z, Wang J, Wang S, Liu L, Yu CL, Song ZB, Bao YL, Zheng LH, Sun Y, Wang G, Huang Y, Yi J, Sun L, Li Y
The Journal of biological chemistry 2020 Sep 11;295(37):12975-12992
The Journal of biological chemistry 2020 Sep 11;295(37):12975-12992
The protoapigenone analog WYC0209 targets CD133+ cells: A potential adjuvant agent against cancer stem cells in urothelial cancer therapy.
Yeh BW, Yu LE, Li CC, Yang JC, Li WM, Wu YC, Wei YC, Lee HT, Kung ML, Wu WJ
Toxicology and applied pharmacology 2020 Sep 1;402:115129
Toxicology and applied pharmacology 2020 Sep 1;402:115129
The vicious cycle between ferritinophagy and ROS production triggered EMT inhibition of gastric cancer cells was through p53/AKT/mTor pathway.
Xu Z, Feng J, Li Y, Guan D, Chen H, Zhai X, Zhang L, Li C, Li C
Chemico-biological interactions 2020 Sep 1;328:109196
Chemico-biological interactions 2020 Sep 1;328:109196
Tp53 Suppression Promotes Cardiomyocyte Proliferation during Zebrafish Heart Regeneration.
Shoffner A, Cigliola V, Lee N, Ou J, Poss KD
Cell reports 2020 Sep 1;32(9):108089
Cell reports 2020 Sep 1;32(9):108089
Downregulation of PIF1, a potential new target of MYCN, induces apoptosis and inhibits cell migration in neuroblastoma cells.
Chen B, Hua Z, Gong B, Tan X, Zhang S, Li Q, Chen Y, Zhang J, Li Z
Life sciences 2020 Sep 1;256:117820
Life sciences 2020 Sep 1;256:117820
Four active monomers from Moutan Cortex exert inhibitory effects against oxidative stress by activating Nrf2/Keap1 signaling pathway.
Zhang B, Yu D, Luo N, Yang C, Zhu Y
The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology 2020 Sep 1;24(5):373-384
The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology 2020 Sep 1;24(5):373-384
FERMT1 promotes gastric cancer progression by activating the NF-κB pathway and predicts poor prognosis.
Fan H, Zhang S, Zhang Y, Liang W, Cao B
Cancer biology & therapy 2020 Sep 1;21(9):815-825
Cancer biology & therapy 2020 Sep 1;21(9):815-825
A novel antiviral lncRNA, EDAL, shields a T309 O-GlcNAcylation site to promote EZH2 lysosomal degradation.
Sui B, Chen D, Liu W, Wu Q, Tian B, Li Y, Hou J, Liu S, Xie J, Jiang H, Luo Z, Lv L, Huang F, Li R, Zhang C, Tian Y, Cui M, Zhou M, Chen H, Fu ZF, Zhang Y, Zhao L
Genome biology 2020 Sep 1;21(1):228
Genome biology 2020 Sep 1;21(1):228
Expression Level of Small Envelope Protein in Addition to Sequence Divergence inside Its Major Hydrophilic Region Contributes to More Efficient Surface Antigen Secretion by Hepatitis B Virus Subgenotype D2 than Subgenotype A2.
Wang Q, Fu S, Zhang J, Yuan Q, Li J, Xia N, Wen YM, Wang Y, Tong S
Viruses 2020 Sep 1;12(9)
Viruses 2020 Sep 1;12(9)
Dual targeting of NUAK1 and ULK1 using the multitargeted inhibitor MRT68921 exerts potent antitumor activities.
Chen Y, Xie X, Wang C, Hu Y, Zhang H, Zhang L, Tu S, He Y, Li Y
Cell death & disease 2020 Sep 1;11(8):712
Cell death & disease 2020 Sep 1;11(8):712
miR-142-5p and miR-130a-3p regulate pulmonary macrophage polarization and asthma airway remodeling.
Shi J, Chen M, Ouyang L, Wang Q, Guo Y, Huang L, Jiang S
Immunology and cell biology 2020 Oct;98(9):715-725
Immunology and cell biology 2020 Oct;98(9):715-725
MiR-375-3p alleviates the severity of inflammation through targeting YAP1/LEKTI pathway in HaCaT cells.
Cheng S, Di Z, Hirman AR, Zheng H, Duo L, Zhai Q, Xu J
Bioscience, biotechnology, and biochemistry 2020 Oct;84(10):2005-2013
Bioscience, biotechnology, and biochemistry 2020 Oct;84(10):2005-2013
Genome-wide pathogenesis interpretation using a heat diffusion-based systems genetics method and implications for gene function annotation.
Quan Y, Zhang QY, Lv BM, Xu RF, Zhang HY
Molecular genetics & genomic medicine 2020 Oct;8(10):e1456
Molecular genetics & genomic medicine 2020 Oct;8(10):e1456
Amyotrophic lateral sclerosis-linked UBQLN2 mutants inhibit endoplasmic reticulum to Golgi transport, leading to Golgi fragmentation and ER stress.
Halloran M, Ragagnin AMG, Vidal M, Parakh S, Yang S, Heng B, Grima N, Shahheydari H, Soo KY, Blair I, Guillemin GJ, Sundaramoorthy V, Atkin JD
Cellular and molecular life sciences : CMLS 2020 Oct;77(19):3859-3873
Cellular and molecular life sciences : CMLS 2020 Oct;77(19):3859-3873
Uncovering the mechanism of Astragali Radix against nephrotic syndrome by intergrating lipidomics and network pharmacology.
Li AP, Yang L, Cui T, Zhang LC, Liu YT, Yan Y, Li K, Qin XM
Phytomedicine : international journal of phytotherapy and phytopharmacology 2020 Oct;77:153274
Phytomedicine : international journal of phytotherapy and phytopharmacology 2020 Oct;77:153274
Senolytic Agent Navitoclax Inhibits Angiotensin II-Induced Heart Failure in Mice.
Jia K, Dai Y, Liu A, Li X, Wu L, Lu L, Bao Y, Jin Q
Journal of cardiovascular pharmacology 2020 Oct;76(4):452-460
Journal of cardiovascular pharmacology 2020 Oct;76(4):452-460
miR-29b-3p protects cardiomyocytes against endotoxin-induced apoptosis and inflammatory response through targeting FOXO3A.
Li Z, Yi N, Chen R, Meng Y, Wang Y, Liu H, Cao W, Hu Y, Gu Y, Tong C, Lu M, Li L, Peng L
Cellular signalling 2020 Oct;74:109716
Cellular signalling 2020 Oct;74:109716
MYCT1 inhibits the EMT and migration of laryngeal cancer cells via the SP1/miR-629-3p/ESRP2 pathway.
Yue PJ, Sun YY, Li YH, Xu ZM, Fu WN
Cellular signalling 2020 Oct;74:109709
Cellular signalling 2020 Oct;74:109709
Blocking NFATc3 ameliorates azoxymethane/dextran sulfate sodium induced colitis-associated colorectal cancer in mice via the inhibition of inflammatory responses and epithelial-mesenchymal transition.
Lin Y, Koumba MH, Qu S, Wang D, Lin L
Cellular signalling 2020 Oct;74:109707
Cellular signalling 2020 Oct;74:109707
Identification of mecciRNAs and their roles in the mitochondrial entry of proteins.
Liu X, Wang X, Li J, Hu S, Deng Y, Yin H, Bao X, Zhang QC, Wang G, Wang B, Shi Q, Shan G
Science China. Life sciences 2020 Oct;63(10):1429-1449
Science China. Life sciences 2020 Oct;63(10):1429-1449
The support of genetic evidence for cardiovascular risk induced by antineoplastic drugs.
Cui H, Zuo S, Liu Z, Liu H, Wang J, You T, Zheng Z, Zhou Y, Qian X, Yao H, Xie L, Liu T, Sham PC, Yu Y, Li MJ
Science advances 2020 Oct;6(42)
Science advances 2020 Oct;6(42)
Upregulation of secreted phosphoprotein 1 affects malignant progression, prognosis, and resistance to cetuximab via the KRAS/MEK pathway in head and neck cancer.
Liu K, Hu H, Jiang H, Liu C, Zhang H, Gong S, Wei D, Yu Z
Molecular carcinogenesis 2020 Oct;59(10):1147-1158
Molecular carcinogenesis 2020 Oct;59(10):1147-1158
MiR-34a suppresses the proliferation and invasion of gastric cancer by modulating PDL1 in the immune microenvironment.
Yong H, Fu J, Gao G, Shi H, Zheng D, Zhou X
Molecular and cellular probes 2020 Oct;53:101601
Molecular and cellular probes 2020 Oct;53:101601
Bovine Milk Exosomes Affect Proliferation and Protect Macrophages against Cisplatin-Induced Cytotoxicity.
Matic S, D'Souza DH, Wu T, Pangloli P, Dia VP
Immunological investigations 2020 Oct;49(7):711-725
Immunological investigations 2020 Oct;49(7):711-725
Generation of homozygous CRISPRa human induced pluripotent stem cell (hiPSC) lines for sustained endogenous gene activation.
Schoger E, Argyriou L, Zimmermann WH, Cyganek L, Zelarayán LC
Stem cell research 2020 Oct;48:101944
Stem cell research 2020 Oct;48:101944
sATP‑binding cassette subfamily G member 2 enhances the multidrug resistance properties of human nasal natural killer/T cell lymphoma side population cells.
Wu S, Zhang X, Dong M, Yang Z, Zhang M, Chen Q
Oncology reports 2020 Oct;44(4):1467-1478
Oncology reports 2020 Oct;44(4):1467-1478
NLRC3 silencing accelerates the invasion of hepatocellular carcinoma cell via IL-6/JAK2/STAT3 pathway activation.
Kang JH, Li MJ, Luan PP, Jiang DK, Chen YW, Xu X, Yu Q, Xu YW, Su Q, Peng WH, Jian WX
Cell biology international 2020 Oct;44(10):2053-2064
Cell biology international 2020 Oct;44(10):2053-2064
Internalization of the TAT-PBX1 fusion protein significantly enhances the proliferation of human hair follicle-derived mesenchymal stem cells and delays their senescence.
Wang B, Liu F, Liu Z, Han X, Lian A, Zhang Y, Zuo K, Wang Y, Liu M, Zou F, Jiang Y, Jin M, Liu X, Liu J
Biotechnology letters 2020 Oct;42(10):1877-1885
Biotechnology letters 2020 Oct;42(10):1877-1885
Pellino1 Contributes to Morphine Tolerance by Microglia Activation via MAPK Signaling in the Spinal Cord of Mice.
Wang L, Yin C, Xu X, Liu T, Wang B, Abdul M, Zhou Y, Cao J, Lu C
Cellular and molecular neurobiology 2020 Oct;40(7):1117-1131
Cellular and molecular neurobiology 2020 Oct;40(7):1117-1131
Tissue Inhibitor of Metalloprotease-1 (TIMP-1) Regulates Adipogenesis of Adipose-derived Stem Cells (ASCs) via the Wnt Signaling Pathway in an MMP-independent Manner.
Wang L, Zhang CG, Jia YL, Hu L
Current medical science 2020 Oct;40(5):989-996
Current medical science 2020 Oct;40(5):989-996
3-Methyladenine Alleviates Experimental Subretinal Fibrosis by Inhibiting Macrophages and M2 Polarization Through the PI3K/Akt Pathway.
Bo Q, Shen M, Xiao M, Liang J, Zhai Y, Zhu H, Jiang M, Wang F, Luo X, Sun X
Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 2020 Oct;36(8):618-628
Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 2020 Oct;36(8):618-628
The role of Caspase-1/GSDMD-mediated pyroptosis in Taxol-induced cell death and a Taxol-resistant phenotype in nasopharyngeal carcinoma regulated by autophagy.
Wang X, Li H, Li W, Xie J, Wang F, Peng X, Song Y, Tan G
Cell biology and toxicology 2020 Oct;36(5):437-457
Cell biology and toxicology 2020 Oct;36(5):437-457
Zbtb20 deficiency causes cardiac contractile dysfunction in mice.
Ren AJ, Chen C, Zhang S, Liu M, Wei C, Wang K, Ma X, Song Y, Wang R, Zhang H, Chen YX, Wu H, Xie Z, Zhang Y, Zhang WJ
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Oct;34(10):13862-13876
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Oct;34(10):13862-13876
Endothelial microparticles induced by cyclic stretch activate Src and modulate cell apoptosis.
Zhuang F, Bao H, Shi Q, Li J, Jiang ZL, Wang Y, Qi YX
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Oct;34(10):13586-13596
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Oct;34(10):13586-13596
Xanthatin alleviates airway inflammation in asthmatic mice by regulating the STAT3/NF-κB signaling pathway.
Chang J, Gao J, Lou L, Chu H, Li P, Chen T, Gao F
Respiratory physiology & neurobiology 2020 Oct;281:103491
Respiratory physiology & neurobiology 2020 Oct;281:103491
Curcumin suppresses the proliferation and tumorigenicity of Cal27 by modulating cancer-associated fibroblasts of TSCC.
Ba P, Xu M, Yu M, Li L, Duan X, Lv S, Fu G, Yang J, Yang P, Yang C, Sun Q
Oral diseases 2020 Oct;26(7):1375-1383
Oral diseases 2020 Oct;26(7):1375-1383
Aloe extract inhibits porcine epidemic diarrhea virus in vitro and in vivo.
Xu Z, Liu Y, Peng P, Liu Y, Huang M, Ma Y, Xue C, Cao Y
Veterinary microbiology 2020 Oct;249:108849
Veterinary microbiology 2020 Oct;249:108849
Emodin inhibiting neutrophil elastase-induced epithelial-mesenchymal transition through Notch1 signalling in alveolar epithelial cells.
Zhou L, Gao R, Hong H, Li X, Yang J, Shen W, Wang Z, Yang J
Journal of cellular and molecular medicine 2020 Oct;24(20):11998-12007
Journal of cellular and molecular medicine 2020 Oct;24(20):11998-12007
Ulinastatin reduces myocardial injury induced by doxorubicin in SD rats.
Zhu JG, Jin K, Ren Y
European review for medical and pharmacological sciences 2020 Oct;24(20):10769-10778
European review for medical and pharmacological sciences 2020 Oct;24(20):10769-10778
Selective blocking of CXCR2 prevents and reverses atrial fibrillation in spontaneously hypertensive rats.
Zhang YL, Teng F, Han X, Li PB, Yan X, Guo SB, Li HH
Journal of cellular and molecular medicine 2020 Oct;24(19):11272-11282
Journal of cellular and molecular medicine 2020 Oct;24(19):11272-11282
Circular RNA circTET3 mediates migration of rat vascular smooth muscle cells by targeting miR-351-5p.
Yao QP, Liu Z, Yao AH, Liu JT, Jiang J, Chen Y, Li SS, Han Y, Jiang ZL, Qi YX
Journal of cellular physiology 2020 Oct;235(10):6831-6842
Journal of cellular physiology 2020 Oct;235(10):6831-6842
Resveratrol inhibits hypertrophic scars formation by activating autophagy via the miR-4654/Rheb axis.
Pang K, Li B, Tang Z, Yang W, Hao L, Shi Z, Zhang J, Cai L, Li R, Liu Y, Lv Q, Ding J, Han C
Molecular medicine reports 2020 Oct;22(4):3440-3452
Molecular medicine reports 2020 Oct;22(4):3440-3452
PRDX2 plays an oncogenic role in esophageal squamous cell carcinoma via Wnt/β-catenin and AKT pathways.
Feng AL, Han X, Meng X, Chen Z, Li Q, Shu W, Dai H, Zhu J, Yang Z
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 2020 Oct;22(10):1838-1848
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 2020 Oct;22(10):1838-1848
Autophagy-Sirt3 axis decelerates hematopoietic aging.
Fang Y, An N, Zhu L, Gu Y, Qian J, Jiang G, Zhao R, Wei W, Xu L, Zhang G, Yao X, Yuan N, Zhang S, Zhao Y, Wang J
Aging cell 2020 Oct;19(10):e13232
Aging cell 2020 Oct;19(10):e13232
Over-activation of NMDA receptors promotes ABCA1 degradation and foam cell formation.
Cheng H, Cheng Q, Bao X, Luo Y, Zhou Y, Li Y, Hua Q, Liu W, Tang S, Feng D, Luo Z
Biochimica et biophysica acta. Molecular and cell biology of lipids 2020 Oct;1865(10):158778
Biochimica et biophysica acta. Molecular and cell biology of lipids 2020 Oct;1865(10):158778
ML-SA1, a selective TRPML agonist, inhibits DENV2 and ZIKV by promoting lysosomal acidification and protease activity.
Xia Z, Wang L, Li S, Tang W, Sun F, Wu Y, Miao L, Cao Z
Antiviral research 2020 Oct;182:104922
Antiviral research 2020 Oct;182:104922
Perillaldehyde: A promising antifungal agent to treat oropharyngeal candidiasis.
Chen L, Qu S, Yang K, Liu M, Li YX, Keller NP, Zeng X, Tian J
Biochemical pharmacology 2020 Oct;180:114201
Biochemical pharmacology 2020 Oct;180:114201
TGF-β1-induced miR-424 promotes pulmonary myofibroblast differentiation by targeting Slit2 protein expression.
Huang Y, Xie Y, Abel PW, Wei P, Plowman J, Toews ML, Strah H, Siddique A, Bailey KL, Tu Y
Biochemical pharmacology 2020 Oct;180:114172
Biochemical pharmacology 2020 Oct;180:114172
Inhibition of RUNX1 promotes cisplatin-induced apoptosis in ovarian cancer cells.
Xiao L, Peng Z, Zhu A, Xue R, Lu R, Mi J, Xi S, Chen W, Jiang S
Biochemical pharmacology 2020 Oct;180:114116
Biochemical pharmacology 2020 Oct;180:114116
Peli1 impairs microglial Aβ phagocytosis through promoting C/EBPβ degradation.
Xu J, Yu T, Pietronigro EC, Yuan J, Arioli J, Pei Y, Luo X, Ye J, Constantin G, Mao C, Xiao Y
PLoS biology 2020 Oct;18(10):e3000837
PLoS biology 2020 Oct;18(10):e3000837
The Long Noncoding RNA NEAT1 Promotes Sarcoma Metastasis by Regulating RNA Splicing Pathways.
Huang J, Sachdeva M, Xu E, Robinson TJ, Luo L, Ma Y, Williams NT, Lopez O, Cervia LD, Yuan F, Qin X, Zhang D, Owzar K, Gokgoz N, Seto A, Okada T, Singer S, Andrulis IL, Wunder JS, Lazar AJ, Rubin BP, Pipho K, Mello SS, Giudice J, Kirsch DG
Molecular cancer research : MCR 2020 Oct;18(10):1534-1544
Molecular cancer research : MCR 2020 Oct;18(10):1534-1544
Antidiabetic activity in vitro and in vivo of BDB, a selective inhibitor of protein tyrosine phosphatase 1B, from Rhodomela confervoides.
Luo J, Zheng M, Jiang B, Li C, Guo S, Wang L, Li X, Yu R, Shi D
British journal of pharmacology 2020 Oct;177(19):4464-4480
British journal of pharmacology 2020 Oct;177(19):4464-4480
The human ribosomal protein eL29 binds in vivo to the cognate mRNA by interacting with its coding sequence, as revealed from in-cell cross-linking data.
Babaylova ES, Kolobova AV, Gopanenko AV, Tupikin AE, Kabilov MR, Malygin AA, Karpova GG
Biochimie 2020 Oct;177:68-77
Biochimie 2020 Oct;177:68-77
RAGE Signaling pathway in hippocampus dentate gyrus involved in GLT-1 decrease induced by chronic unpredictable stress in rats.
Yang F, Wang H, Chen H, Ran D, Tang Q, Weng P, Sun Y, Jiang W
Brain research bulletin 2020 Oct;163:49-56
Brain research bulletin 2020 Oct;163:49-56
Melatonin improves hypoxic-ischemic brain damage through the Akt/Nrf2/Gpx4 signaling pathway.
Gou Z, Su X, Hu X, Zhou Y, Huang L, Fan Y, Li J, Lu L
Brain research bulletin 2020 Oct;163:40-48
Brain research bulletin 2020 Oct;163:40-48
RNA demethylase Alkbh5 is widely expressed in neurons and decreased during brain development.
Du T, Li G, Yang J, Ma K
Brain research bulletin 2020 Oct;163:150-159
Brain research bulletin 2020 Oct;163:150-159
Inhibition of cell migration and induction of apoptosis by a novel class II histone deacetylase inhibitor, MCC2344.
Dawood M, Fleischer E, Klinger A, Bringmann G, Shan L, Efferth T
Pharmacological research 2020 Oct;160:105076
Pharmacological research 2020 Oct;160:105076
Enhancing PPARγ by HDAC inhibition reduces foam cell formation and atherosclerosis in ApoE deficient mice.
Gao Q, Wei A, Chen F, Chen X, Ding W, Ding Z, Wu Z, Du R, Cao W
Pharmacological research 2020 Oct;160:105059
Pharmacological research 2020 Oct;160:105059
p53 promotes ZDHHC1-mediated IFITM3 palmitoylation to inhibit Japanese encephalitis virus replication.
Wang X, Wu Z, Li Y, Yang Y, Xiao C, Liu X, Xiang X, Wei J, Shao D, Liu K, Deng X, Wu J, Qiu Y, Li B, Ma Z
PLoS pathogens 2020 Oct;16(10):e1009035
PLoS pathogens 2020 Oct;16(10):e1009035
STYK1 promotes autophagy through enhancing the assembly of autophagy-specific class III phosphatidylinositol 3-kinase complex I.
Zhou C, Qian X, Hu M, Zhang R, Liu N, Huang Y, Yang J, Zhang J, Bai H, Yang Y, Wang Y, Ali D, Michalak M, Chen XZ, Tang J
Autophagy 2020 Oct;16(10):1786-1806
Autophagy 2020 Oct;16(10):1786-1806
Identification of osalmid metabolic profile and active metabolites with anti-tumor activity in human hepatocellular carcinoma cells.
Wu Z, Zhan Y, Wang L, Tong J, Zhang L, Lin M, Jin X, Jiang L, Lou Y, Qiu Y
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Oct;130:110556
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Oct;130:110556
Therapeutic effect of phycocyanin on acute liver oxidative damage caused by X-ray.
Liu Q, Li W, Qin S
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Oct;130:110553
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Oct;130:110553
miR-483-3p promotes cell proliferation and suppresses apoptosis in rheumatoid arthritis fibroblast-like synoviocytes by targeting IGF-1.
Wang Y, Hou L, Yuan X, Xu N, Zhao S, Yang L, Zhang N
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Oct;130:110519
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Oct;130:110519
Paired like homeodomain 1 and SAM and SH3 domain-containing 1 in the progression and prognosis of head and neck squamous cell carcinoma.
Jin Y, Qin X
The international journal of biochemistry & cell biology 2020 Oct;127:105846
The international journal of biochemistry & cell biology 2020 Oct;127:105846
Lnc-MUC20-9 binds to ROCK1 and functions as a tumor suppressor in bladder cancer.
Dai R, Zhou Y, Chen Z, Zou Z, Pan Z, Liu P, Gao X
Journal of cellular biochemistry 2020 Oct;121(10):4214-4225
Journal of cellular biochemistry 2020 Oct;121(10):4214-4225
Matrix metalloprotease-mediated cleavage of neural glial-related cell adhesion molecules activates quiescent olfactory stem cells via EGFR.
Chen ZH, Luo XC, Yu CR, Huang L
Molecular and cellular neurosciences 2020 Oct;108:103552
Molecular and cellular neurosciences 2020 Oct;108:103552
Renal asymmetric dimethylarginine inhibits fibrosis.
Wu M, Yuan M, Wang Y, Tan B, Huang D, Wang C, Zou Y, Ye C
FEBS open bio 2020 Oct;10(10):2003-2009
FEBS open bio 2020 Oct;10(10):2003-2009
Enhancing site-specific DNA integration by a Cas9 nuclease fused with a DNA donor-binding domain.
Ma S, Wang X, Hu Y, Lv J, Liu C, Liao K, Guo X, Wang D, Lin Y, Rong Z
Nucleic acids research 2020 Oct 9;48(18):10590-10601
Nucleic acids research 2020 Oct 9;48(18):10590-10601
Mir-20a-5p induced WTX deficiency promotes gastric cancer progressions through regulating PI3K/AKT signaling pathway.
Li J, Ye D, Shen P, Liu X, Zhou P, Zhu G, Xu Y, Fu Y, Li X, Sun J, Xu J, Zhang Q
Journal of experimental & clinical cancer research : CR 2020 Oct 8;39(1):212
Journal of experimental & clinical cancer research : CR 2020 Oct 8;39(1):212
Calreticulin promotes EMT in pancreatic cancer via mediating Ca2+ dependent acute and chronic endoplasmic reticulum stress.
Sheng W, Wang G, Tang J, Shi X, Cao R, Sun J, Lin YH, Jia C, Chen C, Zhou J, Dong M
Journal of experimental & clinical cancer research : CR 2020 Oct 7;39(1):209
Journal of experimental & clinical cancer research : CR 2020 Oct 7;39(1):209
miR-431-5p regulates cell proliferation and apoptosis in fibroblast-like synoviocytes in rheumatoid arthritis by targeting XIAP.
Wang Y, Zhang K, Yuan X, Xu N, Zhao S, Hou L, Yang L, Zhang N
Arthritis research & therapy 2020 Oct 6;22(1):231
Arthritis research & therapy 2020 Oct 6;22(1):231
Effect of Zhenxin Xingshui Yizhi Fang on Aβ25-35 induced expression of related transporters in HBMEC cell model.
Wu L, Zheng Q, Guo YY, Zhang KN, Luo J, Xiao S, Li WJ, Yang M
Journal of ethnopharmacology 2020 Oct 5;260:112783
Journal of ethnopharmacology 2020 Oct 5;260:112783
Loss of TMEM106B and PGRN leads to severe lysosomal abnormalities and neurodegeneration in mice.
Feng T, Mai S, Roscoe JM, Sheng RR, Ullah M, Zhang J, Katz II, Yu H, Xiong W, Hu F
EMBO reports 2020 Oct 5;21(10):e50219
EMBO reports 2020 Oct 5;21(10):e50219
Temporal activation of LRH-1 and RAR-γ in human pluripotent stem cells induces a functional naïve-like state.
Taei A, Kiani T, Taghizadeh Z, Moradi S, Samadian A, Mollamohammadi S, Sharifi-Zarchi A, Guenther S, Akhlaghpour A, Asgari Abibeiglou B, Najar-Asl M, Karamzadeh R, Khalooghi K, Braun T, Hassani SN, Baharvand H
EMBO reports 2020 Oct 5;21(10):e47533
EMBO reports 2020 Oct 5;21(10):e47533
Blockade of Glial Connexin 43 Hemichannels Reduces Food Intake.
Guillebaud F, Barbot M, Barbouche R, Brézun JM, Poirot K, Vasile F, Lebrun B, Rouach N, Dallaporta M, Gaige S, Troadec JD
Cells 2020 Oct 31;9(11)
Cells 2020 Oct 31;9(11)
Defect of SLC38A3 promotes epithelial-mesenchymal transition and predicts poor prognosis in esophageal squamous cell carcinoma.
Liu R, Hong R, Wang Y, Gong Y, Yeerken D, Yang D, Li J, Fan J, Chen J, Zhang W, Zhan Q
Chinese journal of cancer research = Chung-kuo yen cheng yen chiu 2020 Oct 31;32(5):547-563
Chinese journal of cancer research = Chung-kuo yen cheng yen chiu 2020 Oct 31;32(5):547-563
IGF2BP1 silencing inhibits proliferation and induces apoptosis of high glucose-induced non-small cell lung cancer cells by regulating Netrin-1.
Zhang J, Luo W, Chi X, Zhang L, Ren Q, Wang H, Zhang W
Archives of biochemistry and biophysics 2020 Oct 30;693:108581
Archives of biochemistry and biophysics 2020 Oct 30;693:108581
Cancer-associated fibroblasts-derived exosomal miR-17-5p promotes colorectal cancer aggressive phenotype by initiating a RUNX3/MYC/TGF-β1 positive feedback loop.
Zhang Y, Wang S, Lai Q, Fang Y, Wu C, Liu Y, Li Q, Wang X, Gu C, Chen J, Cai J, Li A, Liu S
Cancer letters 2020 Oct 28;491:22-35
Cancer letters 2020 Oct 28;491:22-35
HIF-1α-Mediated Mitophagy Determines ZnO Nanoparticle-Induced Human Osteosarcoma Cell Death both In Vitro and In Vivo.
He G, Pan X, Liu X, Zhu Y, Ma Y, Du C, Liu X, Mao C
ACS applied materials & interfaces 2020 Oct 28;12(43):48296-48309
ACS applied materials & interfaces 2020 Oct 28;12(43):48296-48309
Circular RNA circ_PVT1 induces epithelial-mesenchymal transition to promote metastasis of cervical cancer.
Wang H, Wei M, Kang Y, Xing J, Zhao Y
Aging 2020 Oct 27;12(20):20139-20151
Aging 2020 Oct 27;12(20):20139-20151
Nicotine Causes Nephrotoxicity through the Induction of NLRP6 Inflammasome and Alpha7 Nicotinic Acetylcholine Receptor.
Zheng CM, Lee YH, Chiu IJ, Chiu YJ, Sung LC, Hsu YH, Chiu HW
Toxics 2020 Oct 26;8(4)
Toxics 2020 Oct 26;8(4)
A Dedicated Evolutionarily Conserved Molecular Network Licenses Differentiated Cells to Return to the Cell Cycle.
Miao ZF, Lewis MA, Cho CJ, Adkins-Threats M, Park D, Brown JW, Sun JX, Burclaff JR, Kennedy S, Lu J, Mahar M, Vietor I, Huber LA, Davidson NO, Cavalli V, Rubin DC, Wang ZN, Mills JC
Developmental cell 2020 Oct 26;55(2):178-194.e7
Developmental cell 2020 Oct 26;55(2):178-194.e7
CACNA1B facilitates breast cancer cell growth and migration by regulating cyclin D1 and EMT: the implication of CACNA1B in breast cancer.
Jin YM, Ye Y, Bao WQ, Tong Y, Ni SB, Liu JP, Zhao B
Journal of receptor and signal transduction research 2020 Oct 26;:1-8
Journal of receptor and signal transduction research 2020 Oct 26;:1-8
Myostatin regulates fatty acid desaturation and fat deposition through MEF2C/miR222/SCD5 cascade in pigs.
Ren H, Xiao W, Qin X, Cai G, Chen H, Hua Z, Cheng C, Li X, Hua W, Xiao H, Zhang L, Dai J, Zheng X, Zhu Z, Qian C, Yao J, Bi Y
Communications biology 2020 Oct 23;3(1):612
Communications biology 2020 Oct 23;3(1):612
Inhibition of ROS/NLRP3/Caspase-1 mediated pyroptosis attenuates cadmium-induced apoptosis in duck renal tubular epithelial cells.
Wei Z, Nie G, Yang F, Pi S, Wang C, Cao H, Guo X, Liu P, Li G, Hu G, Zhang C
Environmental pollution (Barking, Essex : 1987) 2020 Oct 23;273:115919
Environmental pollution (Barking, Essex : 1987) 2020 Oct 23;273:115919
PD-1 Regulates GABAergic Neurotransmission and GABA-Mediated Analgesia and Anesthesia.
Jiang C, Wang Z, Donnelly CR, Wang K, Andriessen AS, Tao X, Matsuda M, Zhao J, Ji RR
iScience 2020 Oct 23;23(10):101570
iScience 2020 Oct 23;23(10):101570
USP52 regulates DNA end resection and chemosensitivity through removing inhibitory ubiquitination from CtIP.
Gao M, Guo G, Huang J, Kloeber JA, Zhao F, Deng M, Tu X, Kim W, Zhou Q, Zhang C, Yin P, Luo K, Lou Z
Nature communications 2020 Oct 23;11(1):5362
Nature communications 2020 Oct 23;11(1):5362
Functional validation of a human GLUD2 variant in a murine model of Parkinson's disease.
Zhang W, Gong J, Ding L, Zhang Z, Pan X, Chen X, Guo W, Zhang X, Yang X, Peng G, Lin Y, Gao F, Li Y, Zhu X, Xuan A, Wang S, Sun X, Zhang Y, Xu P
Cell death & disease 2020 Oct 22;11(10):897
Cell death & disease 2020 Oct 22;11(10):897
Phosphodiesterase 2A2 regulates mitochondria clearance through Parkin-dependent mitophagy.
Lobo MJ, Reverte-Salisa L, Chao YC, Koschinski A, Gesellchen F, Subramaniam G, Jiang H, Pace S, Larcom N, Paolocci E, Pfeifer A, Zanivan S, Zaccolo M
Communications biology 2020 Oct 21;3(1):596
Communications biology 2020 Oct 21;3(1):596
Loss of PRCD alters number and packaging density of rhodopsin in rod photoreceptor disc membranes.
Sechrest ER, Murphy J, Senapati S, Goldberg AFX, Park PS, Kolandaivelu S
Scientific reports 2020 Oct 21;10(1):17885
Scientific reports 2020 Oct 21;10(1):17885
Emergence of Carbapenem-Resistant Providencia rettgeri and Providencia stuartii Producing IMP-Type Metallo-β-Lactamase in Japan.
Iwata S, Tada T, Hishinuma T, Tohya M, Oshiro S, Kuwahara-Arai K, Ogawa M, Shimojima M, Kirikae T
Antimicrobial agents and chemotherapy 2020 Oct 20;64(11)
Antimicrobial agents and chemotherapy 2020 Oct 20;64(11)
A Regulation Loop between YAP and NR4A1 Balances Cell Proliferation and Apoptosis.
He L, Yuan L, Yu W, Sun Y, Jiang D, Wang X, Feng X, Wang Z, Xu J, Yang R, Zhang W, Feng H, Chen HZ, Zeng YA, Hui L, Wu Q, Zhang Y, Zhang L
Cell reports 2020 Oct 20;33(3):108284
Cell reports 2020 Oct 20;33(3):108284
Novel Therapeutic Insights in Dedifferentiated Liposarcoma: A Role for FGFR and MDM2 Dual Targeting.
Dadone-Montaudié B, Laroche-Clary A, Mongis A, Chamorey E, Mauro ID, Chaire V, Finetti P, Schiappa R, Le Loarer F, Birtwisle-Peyrottes I, Michiels JF, Bertucci F, Pedeutour F, Italiano A, Bianchini L
Cancers 2020 Oct 20;12(10)
Cancers 2020 Oct 20;12(10)
Targeting interleukin-17 receptor B enhances gemcitabine sensitivity through downregulation of mucins in pancreatic cancer.
Tsai LH, Hsu KW, Chiang CM, Yang HJ, Liu YH, Yang SF, Peng PH, Cheng WC, Wu HH
Scientific reports 2020 Oct 20;10(1):17817
Scientific reports 2020 Oct 20;10(1):17817
Expression of STAT1 is positively correlated with PD-L1 in human ovarian cancer.
Liu F, Liu J, Zhang J, Shi J, Gui L, Xu G
Cancer biology & therapy 2020 Oct 2;21(10):963-971
Cancer biology & therapy 2020 Oct 2;21(10):963-971
Multiple-Purpose Connectivity Map Analysis Reveals the Benefits of Esculetin to Hyperuricemia and Renal Fibrosis.
Wang Y, Kong W, Wang L, Zhang T, Huang B, Meng J, Yang B, Xie Z, Zhou H
International journal of molecular sciences 2020 Oct 18;21(20)
International journal of molecular sciences 2020 Oct 18;21(20)
Antioxidant Apigenin Relieves Age-Related Muscle Atrophy by Inhibiting Oxidative Stress and Hyperactive Mitophagy and Apoptosis in Skeletal Muscle of Mice.
Wang D, Yang Y, Zou X, Zhang J, Zheng Z, Wang Z
The journals of gerontology. Series A, Biological sciences and medical sciences 2020 Oct 15;75(11):2081-2088
The journals of gerontology. Series A, Biological sciences and medical sciences 2020 Oct 15;75(11):2081-2088
Autophagy regulates exosome secretion in rat nucleus pulposus cells via the RhoC/ROCK2 pathway.
Hu SQ, Zhang QC, Meng QB, Hu AN, Zou JP, Li XL
Experimental cell research 2020 Oct 15;395(2):112239
Experimental cell research 2020 Oct 15;395(2):112239
SARS-CoV-2 targets neurons of 3D human brain organoids.
Ramani A, Müller L, Ostermann PN, Gabriel E, Abida-Islam P, Müller-Schiffmann A, Mariappan A, Goureau O, Gruell H, Walker A, Andrée M, Hauka S, Houwaart T, Dilthey A, Wohlgemuth K, Omran H, Klein F, Wieczorek D, Adams O, Timm J, Korth C, Schaal H, Gopalakrishnan J
The EMBO journal 2020 Oct 15;39(20):e106230
The EMBO journal 2020 Oct 15;39(20):e106230
XK is a partner for VPS13A: a molecular link between Chorea-Acanthocytosis and McLeod Syndrome.
Park JS, Neiman AM
Molecular biology of the cell 2020 Oct 15;31(22):2425-2436
Molecular biology of the cell 2020 Oct 15;31(22):2425-2436
Ambient fine particulate matter induced the elevation of blood pressure through ACE2/Ang(1-7) pathway: The evidence from urine metabolites.
Du X, Zeng X, Zhang J, Pan K, Song L, Zhou J, Zhou L, Xie Y, Sun Q, Ge W, Chen R, Zhao J, Kan H
Ecotoxicology and environmental safety 2020 Oct 15;203:111044
Ecotoxicology and environmental safety 2020 Oct 15;203:111044
A novel pectin from Polygala tenuifolia blocks Aβ42 aggregation and production by enhancing insulin-degradation enzyme and neprilysin.
Zeng H, Li P, Zhou L, Ding K
International journal of biological macromolecules 2020 Oct 15;161:35-43
International journal of biological macromolecules 2020 Oct 15;161:35-43
Structures and anti-atherosclerotic effects of 1,6-α-glucans from Fructus Corni.
Zhang XW, Sui Y, Liu XX, Fu CY, Qiao YH, Liu WJ, Li ZZ, Li XQ, Cao W
International journal of biological macromolecules 2020 Oct 15;161:1346-1357
International journal of biological macromolecules 2020 Oct 15;161:1346-1357
Melatonin suppresses ER stress-dependent proapoptotic effects via AMPK in bone mesenchymal stem cells during mitochondrial oxidative damage.
Fan C, Feng J, Tang C, Zhang Z, Feng Y, Duan W, Zhai M, Yan Z, Zhu L, Feng L, Zhu H, Luo E
Stem cell research & therapy 2020 Oct 15;11(1):442
Stem cell research & therapy 2020 Oct 15;11(1):442
BKCa channels regulate the immunomodulatory properties of WJ-MSCs by affecting the exosome protein profiles during the inflammatory response.
Song A, Wang J, Tong Y, Fang J, Zhang Y, Zhang H, Ruan H, Wang K, Liu Y
Stem cell research & therapy 2020 Oct 15;11(1):440
Stem cell research & therapy 2020 Oct 15;11(1):440
Identification of Fibroblast Activation Protein as an Osteogenic Suppressor and Anti-osteoporosis Drug Target.
Wei H, Xu Y, Wang Y, Xu L, Mo C, Li L, Shen B, Sun Y, Cheng P, Yang L, Pang Y, Qin A, Cao Y, Morrison SJ, Yue R
Cell reports 2020 Oct 13;33(2):108252
Cell reports 2020 Oct 13;33(2):108252
PERK controls bone homeostasis through the regulation of osteoclast differentiation and function.
Guo J, Ren R, Sun K, Yao X, Lin J, Wang G, Guo Z, Xu T, Guo F
Cell death & disease 2020 Oct 13;11(10):847
Cell death & disease 2020 Oct 13;11(10):847
TAp63α targeting of Lgr5 mediates colorectal cancer stem cell properties and sulforaphane inhibition.
Chen Y, Wang MH, Zhu JY, Xie CF, Li XT, Wu JS, Geng SS, Han HY, Zhong CY
Oncogenesis 2020 Oct 10;9(10):89
Oncogenesis 2020 Oct 10;9(10):89
USP7 mediates pathological hepatic de novo lipogenesis through promoting stabilization and transcription of ZNF638.
Ni W, Lin S, Bian S, Zheng W, Qu L, Fan Y, Lu C, Xiao M, Zhou P
Cell death & disease 2020 Oct 10;11(10):843
Cell death & disease 2020 Oct 10;11(10):843
Landscape characterization of chimeric RNAs in colorectal cancer.
Wu H, Singh S, Xie Z, Li X, Li H
Cancer letters 2020 Oct 1;489:56-65
Cancer letters 2020 Oct 1;489:56-65
The RNA exosome complex degrades expanded hexanucleotide repeat RNA in C9orf72 FTLD/ALS.
Kawabe Y, Mori K, Yamashita T, Gotoh S, Ikeda M
The EMBO journal 2020 Oct 1;39(19):e102700
The EMBO journal 2020 Oct 1;39(19):e102700
3-Mercaptopyruvate sulfurtransferase/hydrogen sulfide protects cerebral endothelial cells against oxygen-glucose deprivation/reoxygenation-induced injury via mitoprotection and inhibition of the RhoA/ROCK pathway.
Zhang F, Chen S, Wen JY, Chen ZW
American journal of physiology. Cell physiology 2020 Oct 1;319(4):C720-C733
American journal of physiology. Cell physiology 2020 Oct 1;319(4):C720-C733
Type 2 diabetes-induced overactivation of P300 contributes to skeletal muscle atrophy by inhibiting autophagic flux.
Fan Z, Wu J, Chen QN, Lyu AK, Chen JL, Sun Y, Lyu Q, Zhao YX, Guo A, Liao ZY, Yang YF, Zhu SY, Jiang XS, Chen B, Xiao Q
Life sciences 2020 Oct 1;258:118243
Life sciences 2020 Oct 1;258:118243
Role and mechanism of PI3K/AKT/FoxO1/PDX-1 signaling pathway in functional changes of pancreatic islets in rats after severe burns.
Zhang B, Sun P, Shen C, Liu X, Sun J, Li D, Liu Z, Zhang W, Zhang K, Niu Y
Life sciences 2020 Oct 1;258:118145
Life sciences 2020 Oct 1;258:118145
Platycodon grandifloras polysaccharides inhibit mitophagy injury induced by Cr (VI) in DF-1 cells.
Hao J, Song Y, Tian B, Qi C, Li L, Wang L, Xing Y, Zhao X, Liu J
Ecotoxicology and environmental safety 2020 Oct 1;202:110901
Ecotoxicology and environmental safety 2020 Oct 1;202:110901
Targeting Mitochondria-Located circRNA SCAR Alleviates NASH via Reducing mROS Output.
Zhao Q, Liu J, Deng H, Ma R, Liao JY, Liang H, Hu J, Li J, Guo Z, Cai J, Xu X, Gao Z, Su S
Cell 2020 Oct 1;183(1):76-93.e22
Cell 2020 Oct 1;183(1):76-93.e22
Amifostine ameliorates induction of experimental autoimmune encephalomyelitis: Effect on reactive oxygen species/NLRP3 pathway.
Li J, Wu DM, Yu Y, Deng SH, Liu T, Zhang T, He M, Zhao YY, Xu Y
International immunopharmacology 2020 Nov;88:106998
International immunopharmacology 2020 Nov;88:106998
microRNA-421-3p prevents inflammatory response in cerebral ischemia/reperfusion injury through targeting m6A Reader YTHDF1 to inhibit p65 mRNA translation.
Zheng L, Tang X, Lu M, Sun S, Xie S, Cai J, Zan J
International immunopharmacology 2020 Nov;88:106937
International immunopharmacology 2020 Nov;88:106937
Wilms' tumor 1-associating protein contributes to psoriasis by promoting keratinocytes proliferation via regulating cyclinA2 and CDK2.
Kong Y, Wu R, Zhang S, Zhao M, Wu H, Lu Q, Fu S, Su Y
International immunopharmacology 2020 Nov;88:106918
International immunopharmacology 2020 Nov;88:106918
PDLIM2 protects articular chondrocytes from lipopolysaccharide-induced apoptosis, degeneration and inflammatory injury through down-regulation of nuclear factor (NF)-κB signaling.
Guo Q, Xu J, Shi Q, Wu S
International immunopharmacology 2020 Nov;88:106883
International immunopharmacology 2020 Nov;88:106883
Emodin ameliorates ovalbumin-induced airway remodeling in mice by suppressing airway smooth muscle cells proliferation.
Liu Y, Li X, He C, Chen R, Wei L, Meng L, Zhang C
International immunopharmacology 2020 Nov;88:106855
International immunopharmacology 2020 Nov;88:106855
The role of WNT1 mutant variant (WNT1c.677C>T ) in osteogenesis imperfecta.
Zhang B, Li R, Wang W, Zhou X, Luo B, Zhu Z, Zhang X, Ding A
Annals of human genetics 2020 Nov;84(6):447-455
Annals of human genetics 2020 Nov;84(6):447-455
Ginsenoside Rg3 attenuates ovariectomy-induced osteoporosis via AMPK/mTOR signaling pathway.
Zhang X, Huang F, Chen X, Wu X, Zhu J
Drug development research 2020 Nov;81(7):875-884
Drug development research 2020 Nov;81(7):875-884
RSPO3 is a marker candidate for predicting tumor aggressiveness in ovarian cancer.
Gu H, Tu H, Liu L, Liu T, Liu Z, Zhang W, Liu J
Annals of translational medicine 2020 Nov;8(21):1351
Annals of translational medicine 2020 Nov;8(21):1351
SOX2 promotes resistance of melanoma with PD-L1 high expression to T-cell-mediated cytotoxicity that can be reversed by SAHA.
Wu R, Wang C, Li Z, Xiao J, Li C, Wang X, Kong P, Cao J, Huang F, Li Z, Huang Y, Chen Y, Li X, Yang D, Zhang H, Mai J, Feng G, Deng R, Zhu X
Journal for immunotherapy of cancer 2020 Nov;8(2)
Journal for immunotherapy of cancer 2020 Nov;8(2)
The metabolic response to inflammation in astrocytes is regulated by nuclear factor-kappa B signaling.
Robb JL, Hammad NA, Weightman Potter PG, Chilton JK, Beall C, Ellacott KLJ
Glia 2020 Nov;68(11):2246-2263
Glia 2020 Nov;68(11):2246-2263
The molecular basis of tight nuclear tethering and inactivation of cGAS.
Zhao B, Xu P, Rowlett CM, Jing T, Shinde O, Lei Y, West AP, Liu WR, Li P
Nature 2020 Nov;587(7835):673-677
Nature 2020 Nov;587(7835):673-677
Loss of core fucosylation enhances the anticancer activity of cytotoxic T lymphocytes by increasing PD-1 degradation.
Zhang N, Li M, Xu X, Zhang Y, Liu Y, Zhao M, Li P, Chen J, Fukuda T, Gu J, Jin X, Li W
European journal of immunology 2020 Nov;50(11):1820-1833
European journal of immunology 2020 Nov;50(11):1820-1833
N‑linoleyltyrosine protects PC12 cells against oxidative damage via autophagy: Possible involvement of CB1 receptor regulation.
Liu X, Wu Y, Zhou D, Xie Y, Zhou Y, Lu Y, Yang R, Liu S
International journal of molecular medicine 2020 Nov;46(5):1827-1837
International journal of molecular medicine 2020 Nov;46(5):1827-1837
Association of tricellulin expression with poor colorectal cancer prognosis and metastasis.
Zhang JX, Qin MB, Ye Z, Peng P, Li SM, Song Q, Lin L, Liu SQ, Xie LH, Zhu Y, Huang JA
Oncology reports 2020 Nov;44(5):2174-2184
Oncology reports 2020 Nov;44(5):2174-2184
Caveolin-1 upregulates Fut8 expression by activating the Wnt/β-catenin pathway to enhance HCC cell proliferative and invasive ability.
Zhang C, Wu Q, Huang H, Chen X, Huang T, Li W, Zhang J, Liu Y
Cell biology international 2020 Nov;44(11):2202-2212
Cell biology international 2020 Nov;44(11):2202-2212
MG53 protects against contrast-induced acute kidney injury by reducing cell membrane damage and apoptosis.
Liu C, Hu YH, Han Y, Wang YB, Zhang Y, Zhang XQ, He DF, Ren HM, Liu YK, Wang HY, Tan T, Lin PH, Li HC, Rovin BH, Ma JJ, Zeng CY
Acta pharmacologica Sinica 2020 Nov;41(11):1457-1464
Acta pharmacologica Sinica 2020 Nov;41(11):1457-1464
The role of protein kinase C alpha in tri-ortho-cresyl phosphate-induced autophagy in human neuroblastoma SK-N-SH cells.
Deng Q, Jiang L, Mao L, Song XH, He CQ, Li XL, Zhang ZH, Zeng HC, Chen JX, Long DX
Journal of applied toxicology : JAT 2020 Nov;40(11):1480-1490
Journal of applied toxicology : JAT 2020 Nov;40(11):1480-1490
Nanog mediates tobacco smoke-induced enhancement of renal cancer stem cell properties.
Zhang T, Sun H, Liu R, Cao W, Zhang T, Li E, Sun X, Wu W, Yu D, Zhong C
Environmental toxicology 2020 Nov;35(11):1274-1283
Environmental toxicology 2020 Nov;35(11):1274-1283
In vivo immunotoxicity of Gd2 O3 :Eu3+ nanoparticles and the associated molecular mechanism.
Zheng C, Tian X, Cai J, Huang L, Wang S, Yang F, Ma Y, Xie F, Li L
Journal of biochemical and molecular toxicology 2020 Nov;34(11):e22562
Journal of biochemical and molecular toxicology 2020 Nov;34(11):e22562
SNORA71B promotes breast cancer cells across blood-brain barrier by inducing epithelial-mesenchymal transition.
Duan S, Luo X, Zeng H, Zhan X, Yuan C
Breast cancer (Tokyo, Japan) 2020 Nov;27(6):1072-1081
Breast cancer (Tokyo, Japan) 2020 Nov;27(6):1072-1081
RBMX is required for activation of ATR on repetitive DNAs to maintain genome stability.
Zheng T, Zhou H, Li X, Peng D, Yang Y, Zeng Y, Liu H, Ren J, Zhao Y
Cell death and differentiation 2020 Nov;27(11):3162-3176
Cell death and differentiation 2020 Nov;27(11):3162-3176
MyoD1 suppresses cell migration and invasion by inhibiting FUT4 transcription in human gastric cancer cells.
Wu F, Qin Y, Jiang Q, Zhang J, Li F, Li Q, Wang X, Gao Y, Miao J, Guo C, Yang Y, Ni L, Liu L, Zhang S, Huang C
Cancer gene therapy 2020 Nov;27(10-11):773-784
Cancer gene therapy 2020 Nov;27(10-11):773-784
TRPV4 promotes acoustic wave-mediated BBB opening via Ca2+/PKC-δ pathway.
Liao WH, Hsiao MY, Kung Y, Liu HL, Béra JC, Inserra C, Chen WS
Journal of advanced research 2020 Nov;26:15-28
Journal of advanced research 2020 Nov;26:15-28
Hydroquinone inhibits PRV infection in neurons in vitro and in vivo.
Fang L, Gao Y, Lan M, Jiang P, Bai J, Li Y, Wang X
Veterinary microbiology 2020 Nov;250:108864
Veterinary microbiology 2020 Nov;250:108864
ndufa7 plays a critical role in cardiac hypertrophy.
Shi X, Zhang Y, Chen R, Gong Y, Zhang M, Guan R, Rotstein OD, Liu X, Wen XY
Journal of cellular and molecular medicine 2020 Nov;24(22):13151-13162
Journal of cellular and molecular medicine 2020 Nov;24(22):13151-13162
Down-regulated HDAC3 elevates microRNA-495-3p to restrain epithelial-mesenchymal transition and oncogenicity of melanoma cells via reducing TRAF5.
Ma Y, Duan J, Hao X
Journal of cellular and molecular medicine 2020 Nov;24(22):12933-12944
Journal of cellular and molecular medicine 2020 Nov;24(22):12933-12944
Long noncoding RNA TCONS-00106987 promotes atrial electrical remodelling during atrial fibrillation by sponging miR-26 to regulate KCNJ2.
Du J, Li Z, Wang X, Li J, Liu D, Wang X, Wei J, Ma S, Zhang Y, Hou Y
Journal of cellular and molecular medicine 2020 Nov;24(21):12777-12788
Journal of cellular and molecular medicine 2020 Nov;24(21):12777-12788
Cathepsin L promotes angiogenesis by regulating the CDP/Cux/VEGF-D pathway in human gastric cancer.
Pan T, Jin Z, Yu Z, Wu X, Chang X, Fan Z, Li F, Wang X, Li Z, Zhou Q, Li J, Liu B, Su L
Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association 2020 Nov;23(6):974-987
Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association 2020 Nov;23(6):974-987
Overexpression of G3BP1 facilitates the progression of colon cancer by activating β‑catenin signaling.
Li Y, Wang J, Zhong S, Li J, Du W
Molecular medicine reports 2020 Nov;22(5):4403-4411
Molecular medicine reports 2020 Nov;22(5):4403-4411
miR‑155 modulates high glucose‑induced cardiac fibrosis via the Nrf2/HO‑1 signaling pathway.
Li Y, Duan JZ, He Q, Wang CQ
Molecular medicine reports 2020 Nov;22(5):4003-4016
Molecular medicine reports 2020 Nov;22(5):4003-4016
The AKT inhibitor MK2206 suppresses airway inflammation and the pro‑remodeling pathway in a TDI‑induced asthma mouse model.
Cui H, Cheng Y, He Y, Cheng W, Zhao W, Zhao H, Zhou FH, Wang L, Dong J, Cai S
Molecular medicine reports 2020 Nov;22(5):3723-3734
Molecular medicine reports 2020 Nov;22(5):3723-3734
LncRNA GAS5 inhibits NLRP3 inflammasome activation-mediated pyroptosis in diabetic cardiomyopathy by targeting miR-34b-3p/AHR.
Xu Y, Fang H, Xu Q, Xu C, Yang L, Huang C
Cell cycle (Georgetown, Tex.) 2020 Nov;19(22):3054-3065
Cell cycle (Georgetown, Tex.) 2020 Nov;19(22):3054-3065
Crosstalk between pleural mesothelial cell and lung fibroblast contributes to pulmonary fibrosis.
Liu F, Yu F, Lu YZ, Cheng PP, Liang LM, Wang M, Chen SJ, Huang Y, Song LJ, He XL, Xiong L, Xin JB, Ma WL, Ye H
Biochimica et biophysica acta. Molecular cell research 2020 Nov;1867(11):118806
Biochimica et biophysica acta. Molecular cell research 2020 Nov;1867(11):118806
Paired associated magnetic stimulation promotes neural repair in the rat middle cerebral artery occlusion model of stroke.
Gao BY, Sun CC, Xia GH, Zhou ST, Zhang Y, Mao YR, Liu PL, Zheng Y, Zhao D, Li XT, Xu J, Xu DS, Bai YL
Neural regeneration research 2020 Nov;15(11):2047-2056
Neural regeneration research 2020 Nov;15(11):2047-2056
TRAF6 Activates Fibroblasts to Cancer-Associated Fibroblasts through FGF19 in Tumor Microenvironment to Benefit the Malignant Phenotype of Melanoma Cells.
Guo Y, Zhang X, Zeng W, Zhang J, Cai L, Wu Z, Su J, Xiao Y, Liu N, Tang L, Xu X, Chen X, Peng C
The Journal of investigative dermatology 2020 Nov;140(11):2268-2279.e11
The Journal of investigative dermatology 2020 Nov;140(11):2268-2279.e11
Pomegranate flower extract bidirectionally regulates the proliferation, differentiation and apoptosis of 3T3-L1 cells through regulation of PPARγ expression mediated by PI3K-AKT signaling pathway.
Li T, Zhang L, Jin C, Xiong Y, Cheng YY, Chen K
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Nov;131:110769
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Nov;131:110769
Type 2 diabetes mellitus facilitates endometrial hyperplasia progression by activating the proliferative function of mucin O-glycosylating enzyme GALNT2.
Zhou X, Xu Y, Yin D, Zhao F, Hao Z, Zhong Y, Zhang J, Zhang B, Yin X
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Nov;131:110764
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Nov;131:110764
Indirubin alleviates bleomycin-induced pulmonary fibrosis in mice by suppressing fibroblast to myofibroblast differentiation.
Wang Q, Yu J, Hu Y, Chen X, Zhang L, Pan T, Miao K, Mou Y, Xu Y, Xiong W, Wang Y
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Nov;131:110715
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Nov;131:110715
Exosome secreted by human gingival fibroblasts in radiation therapy inhibits osteogenic differentiation of bone mesenchymal stem cells by transferring miR-23a.
Zhuang XM, Zhou B
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Nov;131:110672
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Nov;131:110672
The long noncoding RNA FTX promotes a malignant phenotype in bone marrow mesenchymal stem cells via the miR-186/c-Met axis.
Liu L, Li X, Shi Y, Chen H
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Nov;131:110666
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Nov;131:110666
Enhancement of anti-acne effect of Scutellaria baicalensis extract by fermentation with symbiotic fungus Penicillium decumbens.
Zhu X, Mao Y, Guo M, Yu H, Hao L, Hua Q, Lu Z, Hong M, An F
Journal of bioscience and bioengineering 2020 Nov;130(5):457-463
Journal of bioscience and bioengineering 2020 Nov;130(5):457-463
Nucleoredoxin interaction with flightless-I/actin complex is differentially altered in alcoholic liver disease.
Alarcón-Sánchez BR, Guerrero-Escalera D, Rosas-Madrigal S, Ivette Aparicio-Bautista D, Reyes-Gordillo K, Lakshman MR, Ortiz-Fernández A, Quezada H, Medina-Contreras Ó, Villa-Treviño S, Isael Pérez-Carreón J, Arellanes-Robledo J
Basic & clinical pharmacology & toxicology 2020 Nov;127(5):389-404
Basic & clinical pharmacology & toxicology 2020 Nov;127(5):389-404
NLRC3-like 1 inhibits NOD1-RIPK2 pathway via targeting RIPK2.
Fang H, Wu XM, Hu YW, Song YJ, Zhang J, Chang MX
Developmental and comparative immunology 2020 Nov;112:103769
Developmental and comparative immunology 2020 Nov;112:103769
TGF-β2 interfering oligonucleotides used as adjuvants for microbial vaccines.
Tu L, Sun X, Yang L, Zhang T, Zhang X, Li X, Dong B, Liu Y, Yang M, Wang L, Yu Y
Journal of leukocyte biology 2020 Nov;108(5):1673-1692
Journal of leukocyte biology 2020 Nov;108(5):1673-1692
Overexpression of Dnmt3a ameliorates diabetic muscle atrophy by modulating the Pten/Akt pathway.
Wang M, Wu X, Gan L, Teng Z, Zhang H, Zhang Y
Experimental physiology 2020 Nov;105(11):1918-1927
Experimental physiology 2020 Nov;105(11):1918-1927
Two resveratrol analogs, pinosylvin and 4,4'-dihydroxystilbene, improve oligoasthenospermia in a mouse model by attenuating oxidative stress via the Nrf2-ARE pathway.
Wang CN, Sang MM, Gong SN, Yang JF, Cheng CY, Sun F
Bioorganic chemistry 2020 Nov;104:104295
Bioorganic chemistry 2020 Nov;104:104295
MiR-124-3p promotes trophoblast cell HTR-8/SVneo pyroptosis by targeting placental growth factor.
Tao J, Xia LZ, Liang L, Chen Y, Wei D, Meng J, Wu S, Wang Z
Placenta 2020 Nov;101:176-184
Placenta 2020 Nov;101:176-184
MiR-185-5p ameliorates endoplasmic reticulum stress and renal fibrosis by downregulation of ATF6.
Yuan Q, Xu T, Chen Y, Qu W, Sun D, Liu X, Sun L
Laboratory investigation; a journal of technical methods and pathology 2020 Nov;100(11):1436-1446
Laboratory investigation; a journal of technical methods and pathology 2020 Nov;100(11):1436-1446
Cholestasis impairs hepatic lipid storage via AMPK and CREB signaling in hepatitis B virus surface protein transgenic mice.
Irungbam K, Roderfeld M, Glimm H, Hempel F, Schneider F, Hehr L, Glebe D, Churin Y, Morlock G, Yüce I, Roeb E
Laboratory investigation; a journal of technical methods and pathology 2020 Nov;100(11):1411-1424
Laboratory investigation; a journal of technical methods and pathology 2020 Nov;100(11):1411-1424
Inositol-Requiring Enzyme 1α Promotes Zika Virus Infection through Regulation of Stearoyl Coenzyme A Desaturase 1-Mediated Lipid Metabolism.
Huang Y, Lin Q, Huo Z, Chen C, Zhou S, Ma X, Gao H, Lin Y, Li X, He J, Zhang P, Liu C
Journal of virology 2020 Nov 9;94(23)
Journal of virology 2020 Nov 9;94(23)
Oroxylin A alleviates immunoparalysis of CLP mice by degrading CHOP through interacting with FBXO15.
Zhang Z, Wang Y, Shan Y, Zhou R, Yin W
Scientific reports 2020 Nov 6;10(1):19272
Scientific reports 2020 Nov 6;10(1):19272
Long-wave Ultraviolet Ray Promotes Inflammation in Keloid-derived Fibroblasts by Activating P38-NFκB1 Signaling Pathway.
Niu X, Lin X, Chen X, Xu S, Huang Z, Tang Q
Journal of burn care & research : official publication of the American Burn Association 2020 Nov 30;41(6):1231-1239
Journal of burn care & research : official publication of the American Burn Association 2020 Nov 30;41(6):1231-1239
Macrophage-derived small extracellular vesicles promote biomimetic mineralized collagen-mediated endogenous bone regeneration.
Liu A, Jin S, Fu C, Cui S, Zhang T, Zhu L, Wang Y, Shen SGF, Jiang N, Liu Y
International journal of oral science 2020 Nov 30;12(1):33
International journal of oral science 2020 Nov 30;12(1):33
miR-206 as a prognostic and sensitivity biomarker for platinum chemotherapy in epithelial ovarian cancer.
Yu X, Zhang X, Wang G, Wang B, Ding Y, Zhao J, Liu H, Cui S
Cancer cell international 2020 Nov 3;20(1):534
Cancer cell international 2020 Nov 3;20(1):534
Smyd3-PARP16 axis accelerates unfolded protein response and vascular aging.
Yang D, Wang Q, Wei G, Wu J, Zhu YC, Zhu Q, Ni T, Liu X, Zhu YZ
Aging 2020 Nov 3;12(21):21423-21445
Aging 2020 Nov 3;12(21):21423-21445
Grape Seed Proanthocyanidins Induce Apoptosis and Cell Cycle Arrest of HepG2 Cells Accompanied by Induction of the MAPK Pathway and NAG-1.
Wang L, Zhan J, Huang W
Antioxidants (Basel, Switzerland) 2020 Nov 28;9(12)
Antioxidants (Basel, Switzerland) 2020 Nov 28;9(12)
IQGAP3 interacts with Rad17 to recruit the Mre11-Rad50-Nbs1 complex and contributes to radioresistance in lung cancer.
Zeng Y, Jie X, Wu B, Wu G, Liu L, Xu S
Cancer letters 2020 Nov 28;493:254-265
Cancer letters 2020 Nov 28;493:254-265
Calnexin mediates the maturation of GPI-anchors through ER retention.
Guo XY, Liu YS, Gao XD, Kinoshita T, Fujita M
The Journal of biological chemistry 2020 Nov 27;295(48):16393-16410
The Journal of biological chemistry 2020 Nov 27;295(48):16393-16410
Catalysis of proline isomerization and molecular chaperone activity in a tug-of-war.
Favretto F, Flores D, Baker JD, Strohäker T, Andreas LB, Blair LJ, Becker S, Zweckstetter M
Nature communications 2020 Nov 27;11(1):6046
Nature communications 2020 Nov 27;11(1):6046
SAHA Overcomes 5-FU Resistance in IFIT2-Depleted Oral Squamous Cell Carcinoma Cells.
Regmi P, Lai KC, Liu CJ, Lee TC
Cancers 2020 Nov 26;12(12)
Cancers 2020 Nov 26;12(12)
Effect of conditioned medium from neural stem cells on glioma progression and its protein expression profile analysis.
Zhang GL, Qian C, Zhang SZ, Tuo YH, Zeng BY, Ji YX, Wang YZ
World journal of stem cells 2020 Nov 26;12(11):1396-1409
World journal of stem cells 2020 Nov 26;12(11):1396-1409
Legumain is a predictor of all-cause mortality and potential therapeutic target in acute myocardial infarction.
Yang H, He Y, Zou P, Hu Y, Li X, Tang L, Zhu Z, Tai S, Tu T, Xiao Y, Chen M, Wu C, Zhou S
Cell death & disease 2020 Nov 26;11(11):1014
Cell death & disease 2020 Nov 26;11(11):1014
Protective Effects of Fucoxanthin on High Glucose- and 4-Hydroxynonenal (4-HNE)-Induced Injury in Human Retinal Pigment Epithelial Cells.
Chiang YF, Chen HY, Chang YJ, Shih YH, Shieh TM, Wang KL, Hsia SM
Antioxidants (Basel, Switzerland) 2020 Nov 25;9(12)
Antioxidants (Basel, Switzerland) 2020 Nov 25;9(12)
The effect of whey protein on viral infection and replication of SARS-CoV-2 and pangolin coronavirus in vitro.
Fan H, Hong B, Luo Y, Peng Q, Wang L, Jin X, Chen Y, Hu Y, Shi Y, Li T, Zhuang H, Zhou YH, Tong Y, Xiang K
Signal transduction and targeted therapy 2020 Nov 24;5(1):275
Signal transduction and targeted therapy 2020 Nov 24;5(1):275
Loss of Atg7 causes chaotic nucleosome assembly of mouse bone marrow CD11b+Ly6G- myeloid cells.
Fang Y, Gu Y, Li L, Zhu L, Qian J, Zhao C, Xu L, Wei W, Du Y, Yuan N, Zhang S, Yuan Y, Xu Y, Jiang C, Wang J
Aging 2020 Nov 24;12(24):25673-25683
Aging 2020 Nov 24;12(24):25673-25683
RNAi-mediated silencing of Trichinella spiralis serpin-type serine protease inhibitors results in a reduction in larval infectivity.
Yi N, Yu P, Wu L, Liu Z, Guan J, Liu C, Liu M, Lu Y
Veterinary research 2020 Nov 23;51(1):139
Veterinary research 2020 Nov 23;51(1):139
Calcium and TRPV4 promote metastasis by regulating cytoskeleton through the RhoA/ROCK1 pathway in endometrial cancer.
Li X, Cheng Y, Wang Z, Zhou J, Jia Y, He X, Zhao L, Dong Y, Fan Y, Yang X, Shen B, Wu X, Wang J, Xiong C, Wei L, Li X, Wang J
Cell death & disease 2020 Nov 23;11(11):1009
Cell death & disease 2020 Nov 23;11(11):1009
TDP-43 interacts with amyloid-β, inhibits fibrillization, and worsens pathology in a model of Alzheimer's disease.
Shih YH, Tu LH, Chang TY, Ganesan K, Chang WW, Chang PS, Fang YS, Lin YT, Jin LW, Chen YR
Nature communications 2020 Nov 23;11(1):5950
Nature communications 2020 Nov 23;11(1):5950
MiR-103a-3p promotes tumour glycolysis in colorectal cancer via hippo/YAP1/HIF1A axis.
Sun Z, Zhang Q, Yuan W, Li X, Chen C, Guo Y, Shao B, Dang Q, Zhou Q, Wang Q, Wang G, Liu J, Kan Q
Journal of experimental & clinical cancer research : CR 2020 Nov 20;39(1):250
Journal of experimental & clinical cancer research : CR 2020 Nov 20;39(1):250
Inhibition of ferroptosis alleviates atherosclerosis through attenuating lipid peroxidation and endothelial dysfunction in mouse aortic endothelial cell.
Bai T, Li M, Liu Y, Qiao Z, Wang Z
Free radical biology & medicine 2020 Nov 20;160:92-102
Free radical biology & medicine 2020 Nov 20;160:92-102
Velvet antler polypeptide prevents the disruption of hepatic tight junctions via inhibiting oxidative stress in cholestatic mice and liver cell lines.
Li L, Yang F, Jia R, Yan P, Ma L
Food & function 2020 Nov 18;11(11):9752-9763
Food & function 2020 Nov 18;11(11):9752-9763
The TLR3/IRF1/Type III IFN Axis Facilitates Antiviral Responses against Enterovirus Infections in the Intestine.
Su R, Shereen MA, Zeng X, Liang Y, Li W, Ruan Z, Li Y, Liu W, Liu Y, Wu K, Luo Z, Wu J
mBio 2020 Nov 17;11(6)
mBio 2020 Nov 17;11(6)
Urocortin participates in LPS-induced apoptosis of THP-1 macrophages via S1P-cPLA2 signaling pathway.
Zhu C, Zhou J, Li T, Mu J, Jin L, Li S
European journal of pharmacology 2020 Nov 15;887:173559
European journal of pharmacology 2020 Nov 15;887:173559
Identification and functional analysis of fourteen NR5A1 variants in patients with the 46 XY disorders of sex development.
Na X, Mao Y, Tang Y, Jiang W, Yu J, Cao L, Yang J
Gene 2020 Nov 15;760:145004
Gene 2020 Nov 15;760:145004
Inhibiting Rab27a in renal tubular epithelial cells attenuates the inflammation of diabetic kidney disease through the miR-26a-5p/CHAC1/NF-kB pathway.
Li S, Jia Y, Xue M, Hu F, Zheng Z, Zhang S, Ren S, Yang Y, Si Z, Wang L, Guan M, Xue Y
Life sciences 2020 Nov 15;261:118347
Life sciences 2020 Nov 15;261:118347
USP33 regulates c-Met expression by deubiquitinating SP1 to facilitate metastasis in hepatocellular carcinoma.
Gan Q, Shao J, Cao Y, Lei J, Xie P, Ge J, Hu G
Life sciences 2020 Nov 15;261:118316
Life sciences 2020 Nov 15;261:118316
Macrophage-Derived IL-1β Regulates Emergency Myelopoiesis via the NF-κB and C/ebpβ in Zebrafish.
Wei Z, Li C, Zhang Y, Lin C, Zhang Y, Shu L, Luo L, Zhuo J, Li L
Journal of immunology (Baltimore, Md. : 1950) 2020 Nov 15;205(10):2694-2706
Journal of immunology (Baltimore, Md. : 1950) 2020 Nov 15;205(10):2694-2706
Targeting HMGB3/hTERT axis for radioresistance in cervical cancer.
Li Z, Zhang Y, Sui S, Hua Y, Zhao A, Tian X, Wang R, Guo W, Yu W, Zou K, Deng W, He L, Zou L
Journal of experimental & clinical cancer research : CR 2020 Nov 13;39(1):243
Journal of experimental & clinical cancer research : CR 2020 Nov 13;39(1):243
Autophagic blockage by bismuth sulfide nanoparticles inhibits migration and invasion of HepG2 cells.
Hao BM, Liu YN, Zhang CY, Li GQ, Wang WN, Xu WD, Zha ZB, Wang F, Li C, Miao ZH, Yang XX, Chen YL, Qian HS, Zhou W
Nanotechnology 2020 Nov 13;31(46):465102
Nanotechnology 2020 Nov 13;31(46):465102
The role of macrophage migration inhibitory factor in promoting benign prostatic hyperplasia epithelial cell growth by modulating COX-2 and P53 signaling.
Song H, Shen Q, Hu S, Jin J
Biology open 2020 Nov 12;9(11)
Biology open 2020 Nov 12;9(11)
Electroacupuncture alleviates Parkinson disease and regulates the expression of brain-gut peptides.
Yu J, Min D, Bai Y, Qu L, Zou T, Wang S
Experimental animals 2020 Nov 12;69(4):448-460
Experimental animals 2020 Nov 12;69(4):448-460
Tomatidine inhibits porcine epidemic diarrhea virus replication by targeting 3CL protease.
Wang P, Bai J, Liu X, Wang M, Wang X, Jiang P
Veterinary research 2020 Nov 11;51(1):136
Veterinary research 2020 Nov 11;51(1):136
A CRISPR-Cas9 screen identifies mitochondrial translation as an essential process in latent KSHV infection of human endothelial cells.
Holmes DL, Vogt DT, Lagunoff M
Proceedings of the National Academy of Sciences of the United States of America 2020 Nov 10;117(45):28384-28392
Proceedings of the National Academy of Sciences of the United States of America 2020 Nov 10;117(45):28384-28392
Inhibition of notch enhances the anti-atherosclerotic effects of LXR agonists while reducing fatty liver development in ApoE-deficient mice.
Hao Y, Wang X, Zhang F, Wang M, Wang Y, Wang H, Du Y, Wang T, Fu F, Gao Z, Zhang L
Toxicology and applied pharmacology 2020 Nov 1;406:115211
Toxicology and applied pharmacology 2020 Nov 1;406:115211
Discovery of novel anti-angiogenesis agents. Part 11: Development of PROTACs based on active molecules with potency of promoting vascular normalization.
Shan Y, Si R, Wang J, Zhang Q, Li J, Ma Y, Zhang J
European journal of medicinal chemistry 2020 Nov 1;205:112654
European journal of medicinal chemistry 2020 Nov 1;205:112654
L-lactate preconditioning promotes plasticity-related proteins expression and reduces neurological deficits by potentiating GPR81 signaling in rat traumatic brain injury model.
Zhai X, Li J, Li L, Sun Y, Zhang X, Xue Y, Lv J, Gao Y, Li S, Yan W, Yin S, Xiao Z
Brain research 2020 Nov 1;1746:146945
Brain research 2020 Nov 1;1746:146945
Circ-PGAM1 promotes malignant progression of epithelial ovarian cancer through regulation of the miR-542-3p/CDC5L/PEAK1 pathway.
Zhang C, Li Y, Zhao W, Liu G, Yang Q
Cancer medicine 2020 May;9(10):3500-3521
Cancer medicine 2020 May;9(10):3500-3521
Grape Extract Activates Brown Adipose Tissue Through Pathway Involving the Regulation of Gut Microbiota and Bile Acid.
Han X, Guo J, Yin M, Liu Y, You Y, Zhan J, Huang W
Molecular nutrition & food research 2020 May;64(10):e2000149
Molecular nutrition & food research 2020 May;64(10):e2000149
Lysyl-tRNA synthetase produces diadenosine tetraphosphate to curb STING-dependent inflammation.
Guerra J, Valadao AL, Vlachakis D, Polak K, Vila IK, Taffoni C, Prabakaran T, Marriott AS, Kaczmarek R, Houel A, Auzemery B, Déjardin S, Boudinot P, Nawrot B, Jones NJ, Paludan SR, Kossida S, Langevin C, Laguette N
Science advances 2020 May;6(21):eaax3333
Science advances 2020 May;6(21):eaax3333
CtBP1 transactivates RAD51 and confers cisplatin resistance to breast cancer cells.
Deng Y, Guo W, Xu N, Li F, Li J
Molecular carcinogenesis 2020 May;59(5):512-519
Molecular carcinogenesis 2020 May;59(5):512-519
TRIM22 inhibits endometrial cancer progression through the NOD2/NF‑κB signaling pathway and confers a favorable prognosis.
Zhang L, Zhang B, Wei M, Xu Z, Kong W, Deng K, Xu X, Zhang L, Ζhao X, Yan L
International journal of oncology 2020 May;56(5):1225-1239
International journal of oncology 2020 May;56(5):1225-1239
Mechanism of aberrant long non-coding RNA expression in an adriamycin-resistant liver cancer cell strain.
Wang Y, Wan G, Wang H, Zhang G, Li Z, Lu L, Wu Y, Yu X, Du J
Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 2020 May;52(5):582-587
Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 2020 May;52(5):582-587
MicroRNA‑145‑5p inhibits osteosarcoma cell proliferation by targeting E2F transcription factor 3.
Li H, Pan R, Lu Q, Ren C, Sun J, Wu H, Wen J, Chen H
International journal of molecular medicine 2020 May;45(5):1317-1326
International journal of molecular medicine 2020 May;45(5):1317-1326
DNA methylation‑regulated miR‑155‑5p depresses sensitivity of esophageal carcinoma cells to radiation and multiple chemotherapeutic drugs via suppression of MAP3K10.
Luo W, Zhang H, Liang X, Xia R, Deng H, Yi Q, Lv L, Qian L
Oncology reports 2020 May;43(5):1692-1704
Oncology reports 2020 May;43(5):1692-1704
Ganoderic acid hinders renal fibrosis via suppressing the TGF-β/Smad and MAPK signaling pathways.
Geng XQ, Ma A, He JZ, Wang L, Jia YL, Shao GY, Li M, Zhou H, Lin SQ, Ran JH, Yang BX
Acta pharmacologica Sinica 2020 May;41(5):670-677
Acta pharmacologica Sinica 2020 May;41(5):670-677
PBX1 promotes development of natural killer cells by binding directly to the Nfil3 promoter.
Xu X, Zhou Y, Fu B, Zhang J, Dong Z, Zhang X, Shen N, Sun R, Tian Z, Wei H
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 May;34(5):6479-6492
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 May;34(5):6479-6492
Cognitive improvement and synaptic deficit attenuation by a multifunctional carbazole-based cyanine in AD mice model through regulation of Ca2+/CaMKII/CREB signaling pathway.
Chen C, Xu D, Zhang ZH, Jia SZ, Cao XC, Chen YB, Song GL, Wong MS, Li HW
Experimental neurology 2020 May;327:113210
Experimental neurology 2020 May;327:113210
Yeast β-D-glucan exerts antitumour activity in liver cancer through impairing autophagy and lysosomal function, promoting reactive oxygen species production and apoptosis.
Wang N, Liu H, Liu G, Li M, He X, Yin C, Tu Q, Shen X, Bai W, Wang Q, Tao Y, Yin H
Redox biology 2020 May;32:101495
Redox biology 2020 May;32:101495
BMX activates Wnt/β-catenin signaling pathway to promote cell proliferation and migration in breast cancer.
Li K, Pan WT, Ma YB, Xu XL, Gao Y, He YQ, Wei L, Zhang JW
Breast cancer (Tokyo, Japan) 2020 May;27(3):363-371
Breast cancer (Tokyo, Japan) 2020 May;27(3):363-371
Autophagy related 4B, upregulated by HIF-1α, attenuates the sensitivity to cisplatin in nasopharyngeal carcinoma cells.
Huang J, Li HB, Yu S, Yuan F, Lou ZP
European review for medical and pharmacological sciences 2020 May;24(9):4793-4802
European review for medical and pharmacological sciences 2020 May;24(9):4793-4802
LncRNA ZEB2-AS1 promotes the proliferation, migration and invasion of esophageal squamous cell carcinoma cell through miR-574-3p/HMGA2 axis.
Xu JH, Chen RZ, Liu LY, Li XM, Wu CP, Zhou YT, Yan JD, Zhang ZY
European review for medical and pharmacological sciences 2020 May;24(10):5391-5403
European review for medical and pharmacological sciences 2020 May;24(10):5391-5403
miR-181a/b-5p ameliorates inflammatory response in monocrotaline-induced pulmonary arterial hypertension by targeting endocan.
Zhao H, Guo Y, Sun Y, Zhang N, Wang X
Journal of cellular physiology 2020 May;235(5):4422-4433
Journal of cellular physiology 2020 May;235(5):4422-4433
Altered circadian clock as a novel therapeutic target for constant darkness-induced insulin resistance and hyperandrogenism of polycystic ovary syndrome.
Li S, Zhai J, Chu W, Geng X, Chen ZJ, Du Y
Translational research : the journal of laboratory and clinical medicine 2020 May;219:13-29
Translational research : the journal of laboratory and clinical medicine 2020 May;219:13-29
Mitophagy is involved in chromium (VI)-induced mitochondria damage in DF-1 cells.
Xu Y, Wang X, Geng N, Zhu Y, Zhang S, Liu Y, Liu J
Ecotoxicology and environmental safety 2020 May;194:110414
Ecotoxicology and environmental safety 2020 May;194:110414
Chlorogenic acid rescues zearalenone induced injury to mouse ovarian granulosa cells.
Yi Y, Wan S, Hou Y, Cheng J, Guo J, Wang S, Khan A, Sun N, Li H
Ecotoxicology and environmental safety 2020 May;194:110401
Ecotoxicology and environmental safety 2020 May;194:110401
SOX9 represses hepatitis B virus replication through binding to HBV EnhII/Cp and inhibiting the promoter activity.
Yang H, Zhou Y, Mo J, Xiang Q, Qin M, Liu W, Shang J, Yang Q, Xu W, Yang G, Tan Q, Wu K, Liu Y, Wu J
Antiviral research 2020 May;177:104761
Antiviral research 2020 May;177:104761
Modulation of NR1 receptor by CaMKIIα plays an important role in chronic itch development in mice.
Li NQ, Tang Y, Huang ST, Liu XT, Zeng LP, Li H, Wan L
Brain research bulletin 2020 May;158:66-76
Brain research bulletin 2020 May;158:66-76
RIP3/MLKL-mediated neuronal necroptosis induced by methamphetamine at 39°C.
Guo LM, Wang Z, Li SP, Wang M, Yan WT, Liu FX, Wang CD, Zhang XD, Chen D, Yan J, Xiong K
Neural regeneration research 2020 May;15(5):865-874
Neural regeneration research 2020 May;15(5):865-874
Activation of sirtuin1 protects against ischemia/reperfusion-induced acute kidney injury.
Gong L, He J, Sun X, Li L, Zhang X, Gan H
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 May;125:110021
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 May;125:110021
The natural compound andrographolide inhibits human aortic valve interstitial cell calcification via the NF-kappa B/Akt/ERK pathway.
Huang Y, Zhou X, Liu M, Zhou T, Shi J, Dong N, Xu K
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 May;125:109985
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 May;125:109985
Melanoma suppression by quercein is correlated with RIG-I and type I interferon signaling.
Peng D, Chen L, Sun Y, Sun L, Yin Q, Deng S, Niu L, Lou F, Wang Z, Xu Z, Wang C, Fan L, Wang H, Wang H
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 May;125:109984
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 May;125:109984
Silencing METTL3 inhibits the proliferation and invasion of osteosarcoma by regulating ATAD2.
Zhou L, Yang C, Zhang N, Zhang X, Zhao T, Yu J
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 May;125:109964
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 May;125:109964
ALDH1A1 maintains the cancer stem-like cells properties of esophageal squamous cell carcinoma by activating the AKT signal pathway and interacting with β-catenin.
Wang W, He S, Zhang R, Peng J, Guo D, Zhang J, Xiang B, Li L
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 May;125:109940
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 May;125:109940
Upregulation of nuclear factor (erythroid-derived 2)-like 2 protein level in the human colorectal adenocarcinoma cell line DLD-1 by a heterocyclic organobismuth(III) compound: Effect of organobismuth(III) compound on NRF2 signaling.
Iuchi K, Tasaki Y, Shirai S, Hisatomi H
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 May;125:109928
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 May;125:109928
KIF2A promotes the progression via AKT signaling pathway and is upregulated by transcription factor ETV4 in human gastric cancer.
Zhang X, Wang Y, Liu X, Zhao A, Yang Z, Kong F, Sun L, Yu Y, Jiang L
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 May;125:109840
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 May;125:109840
β-elemene suppresses the malignant behavior of esophageal cancer cells by regulating the phosphorylation of AKT.
Liang Y, Li S, Zheng G, Zhang L
Acta histochemica 2020 May;122(4):151538
Acta histochemica 2020 May;122(4):151538
DACT2 regulates structural and electrical atrial remodeling in atrial fibrillation.
Hou J, Huang S, Long Y, Huang J, Yang S, Yao J, Chen G, Yue Y, Liang M, Mei B, Li J, Wu Z
Journal of thoracic disease 2020 May;12(5):2039-2048
Journal of thoracic disease 2020 May;12(5):2039-2048
Protein kinase CK2 participates in estrogen-mediated endothelial progenitor cell homing to endometriotic lesions through stromal cells in a stromal cell-derived factor-1- CXCR4-dependent manner.
Zhao R, Feng D, Zhuang G, Liu Y, Chi S, Zhang J, Zhou X, Zhang W, Wang H
Fertility and sterility 2020 May;113(5):1067-1079.e5
Fertility and sterility 2020 May;113(5):1067-1079.e5
BMP8A promotes survival and drug resistance via Nrf2/TRIM24 signaling pathway in clear cell renal cell carcinoma.
Yu YP, Cai LC, Wang XY, Cheng SY, Zhang DM, Jian WG, Wang TD, Yang JK, Yang KB, Zhang C
Cancer science 2020 May;111(5):1555-1566
Cancer science 2020 May;111(5):1555-1566
Epithelial V-like antigen 1 promotes hepatocellular carcinoma growth and metastasis via the ERBB-PI3K-AKT pathway.
Ni Q, Chen Z, Zheng Q, Xie D, Li JJ, Cheng S, Ma X
Cancer science 2020 May;111(5):1500-1513
Cancer science 2020 May;111(5):1500-1513
Hydrogen inhibits the osteoclastogenesis of mouse bone marrow mononuclear cells.
Liu Y, Wang DL, Huang YC, Wang TB, Zeng H
Materials science & engineering. C, Materials for biological applications 2020 May;110:110640
Materials science & engineering. C, Materials for biological applications 2020 May;110:110640
Whole transcriptome sequencing reveals dexmedetomidine-improves postoperative cognitive dysfunction in rats via modulating lncRNA.
Deng F, Cai L, Zhou B, Zhou Z, Xu G
3 Biotech 2020 May;10(5):202
3 Biotech 2020 May;10(5):202
Morphometric, Hemodynamic, and Multi-Omics Analyses in Heart Failure Rats with Preserved Ejection Fraction.
Zhang W, Zhang H, Yao W, Li L, Niu P, Huo Y, Tan W
International journal of molecular sciences 2020 May 9;21(9)
International journal of molecular sciences 2020 May 9;21(9)
Rapid Neutralization Testing System for Zika Virus Based on an Enzyme-Linked Immunospot Assay.
Li S, Zhao H, Yang H, Hou W, Cruz-Cosme R, Cao R, Chen C, Wang W, Xu L, Zhang J, Zhong W, Xia N, Tang Q, Cheng T
ACS infectious diseases 2020 May 8;6(5):811-819
ACS infectious diseases 2020 May 8;6(5):811-819
Perturbation of phosphoglycerate kinase 1 (PGK1) only marginally affects glycolysis in cancer cells.
Jin C, Zhu X, Wu H, Wang Y, Hu X
The Journal of biological chemistry 2020 May 8;295(19):6425-6446
The Journal of biological chemistry 2020 May 8;295(19):6425-6446
PHLDA2 regulates EMT and autophagy in colorectal cancer via the PI3K/AKT signaling pathway.
Ma Z, Lou S, Jiang Z
Aging 2020 May 8;12(9):7985-8000
Aging 2020 May 8;12(9):7985-8000
Analysis of the role of the interleukins in colon cancer.
Wei X, Zhang Y, Yang Z, Sha Y, Pan Y, Chen Y, Cai L
Biological research 2020 May 7;53(1):20
Biological research 2020 May 7;53(1):20
Neuropeptide Y1 receptor antagonist promotes osteoporosis and microdamage repair and enhances osteogenic differentiation of bone marrow stem cells via cAMP/PKA/CREB pathway.
Xie W, Li F, Han Y, Qin Y, Wang Y, Chi X, Xiao J, Li Z
Aging 2020 May 7;12(9):8120-8136
Aging 2020 May 7;12(9):8120-8136
Self-responsive co-delivery system for remodeling tumor intracellular microenvironment to promote PTEN-mediated anti-tumor therapy.
Wang Y, Wang R, Wu S, An J, Liang Y, Hou L, Zhang Z
Nanoscale 2020 May 7;12(17):9392-9403
Nanoscale 2020 May 7;12(17):9392-9403
Small-molecule inhibition of aging-associated chromosomal instability delays cellular senescence.
Barroso-Vilares M, Macedo JC, Reis M, Warren JD, Compton D, Logarinho E
EMBO reports 2020 May 6;21(5):e49248
EMBO reports 2020 May 6;21(5):e49248
Naringin inhibits autophagy mediated by PI3K-Akt-mTOR pathway to ameliorate endothelial cell dysfunction induced by high glucose/high fat stress.
Wang K, Peng S, Xiong S, Niu A, Xia M, Xiong X, Zeng G, Huang Q
European journal of pharmacology 2020 May 5;874:173003
European journal of pharmacology 2020 May 5;874:173003
Downregulation of GLYR1 contributes to microsatellite instability colorectal cancer by targeting p21 via the p38MAPK and PI3K/AKT pathways.
Hu Z, Long T, Ma Y, Zhu J, Gao L, Zhong Y, Wang X, Wang X, Li Z
Journal of experimental & clinical cancer research : CR 2020 May 5;39(1):76
Journal of experimental & clinical cancer research : CR 2020 May 5;39(1):76
Kalirin Interacts with TRAPP and Regulates Rab11 and Endosomal Recycling.
Wang X, Weng M, Ke Y, Sapp E, DiFiglia M, Li X
Cells 2020 May 4;9(5)
Cells 2020 May 4;9(5)
The heterocyclic compound Tempol inhibits the growth of cancer cells by interfering with glutamine metabolism.
Ye S, Xu P, Huang M, Chen X, Zeng S, Wang Q, Chen J, Li K, Gao W, Liu R, Liu J, Shao Y, Zhang H, Xu Y, Zhang Q, Zhong Z, Wei Z, Wang J, Hao B, Huang W, Liu Q
Cell death & disease 2020 May 4;11(5):312
Cell death & disease 2020 May 4;11(5):312
Prenatal bisphenol A exposure contributes to Tau pathology: Potential roles of CDK5/GSK3β/PP2A axis in BPA-induced neurotoxicity.
Xue J, Zhang L, Xie X, Gao Y, Jiang L, Wang J, Wang Y, Gao R, Yu J, Xiao H
Toxicology 2020 May 30;438:152442
Toxicology 2020 May 30;438:152442
Pharmacogenomic Analysis Reveals CCNA2 as a Predictive Biomarker of Sensitivity to Polo-Like Kinase I Inhibitor in Gastric Cancer.
Lee Y, Lee CE, Oh S, Kim H, Lee J, Kim SB, Kim HS
Cancers 2020 May 30;12(6)
Cancers 2020 May 30;12(6)
Design, Synthesis, and Biological Evaluation of HSP90 Inhibitor-SN38 Conjugates for Targeted Drug Accumulation.
Zhu S, Shen Q, Gao Y, Wang L, Fang Y, Chen Y, Lu W
Journal of medicinal chemistry 2020 May 28;63(10):5421-5441
Journal of medicinal chemistry 2020 May 28;63(10):5421-5441
PAX6 contributes to the activation and proliferation of hepatic stellate cells via activating Hedgehog/GLI1 pathway.
Li C, Tan YH, Sun J, Deng FM, Liu YL
Biochemical and biophysical research communications 2020 May 28;526(2):314-320
Biochemical and biophysical research communications 2020 May 28;526(2):314-320
Synergistic antifibrotic effects of miR-451 with miR-185 partly by co-targeting EphB2 on hepatic stellate cells.
Chen X, Zhang D, Wang Y, Chen K, Zhao L, Xu Y, Jiang H, Wang S
Cell death & disease 2020 May 28;11(5):402
Cell death & disease 2020 May 28;11(5):402
circStrn3 is involved in bone cancer pain regulation in a rat model.
Zhang Y, Zhang X, Xing Z, Tang S, Chen H, Zhang Z, Li J, Li Y
Acta biochimica et biophysica Sinica 2020 May 26;52(5):495-505
Acta biochimica et biophysica Sinica 2020 May 26;52(5):495-505
Circular RNA circNRIP1 promotes migration and invasion in cervical cancer by sponging miR-629-3p and regulating the PTP4A1/ERK1/2 pathway.
Li X, Ma N, Zhang Y, Wei H, Zhang H, Pang X, Li X, Wu D, Wang D, Yang Z, Zhang S
Cell death & disease 2020 May 26;11(5):399
Cell death & disease 2020 May 26;11(5):399
Evodiamine via targeting nNOS and AMPA receptor GluA1 inhibits nitroglycerin-induced migraine-like response.
Lin J, Zhang X, Li C, Zhang Y, Lu H, Chen J, Li Z, Yang X, Wu Z
Journal of ethnopharmacology 2020 May 23;254:112727
Journal of ethnopharmacology 2020 May 23;254:112727
Delivery of oligonucleotides to bone marrow to modulate ferrochelatase splicing in a mouse model of erythropoietic protoporphyria.
Halloy F, Iyer PS, Ćwiek P, Ghidini A, Barman-Aksözen J, Wildner-Verhey van Wijk N, Theocharides APA, Minder EI, Schneider-Yin X, Schümperli D, Hall J
Nucleic acids research 2020 May 21;48(9):4658-4671
Nucleic acids research 2020 May 21;48(9):4658-4671
Exogenous Therapeutics of Microrna-29a Attenuates Development of Hepatic Fibrosis in Cholestatic Animal Model through Regulation of Phosphoinositide 3-Kinase p85 Alpha.
Yang YL, Wang FS, Lin HY, Huang YH
International journal of molecular sciences 2020 May 21;21(10)
International journal of molecular sciences 2020 May 21;21(10)
KMT2A regulates cervical cancer cell growth through targeting VDAC1.
Zhang C, Hua Y, Qiu H, Liu T, Long Q, Liao W, Qiu J, Wang N, Chen M, Shi D, Yan Y, Xie C, Deng W, Li T, Li Y
Aging 2020 May 21;12(10):9604-9620
Aging 2020 May 21;12(10):9604-9620
Inhibition of protein phosphatase methylesterase 1 dysregulates MAP kinase signaling and attenuates muscle cell differentiation.
Labuzan SA, Lynch SA, Cooper LM, Waddell DS
Gene 2020 May 20;739:144515
Gene 2020 May 20;739:144515
Anti-inflammatory activity of berberine in non-alcoholic fatty liver disease via the Angptl2 pathway.
Lu Z, He B, Chen Z, Yan M, Wu L
BMC immunology 2020 May 19;21(1):28
BMC immunology 2020 May 19;21(1):28
Fatty Acid Synthase Inhibitor G28 Shows Anticancer Activity in EGFR Tyrosine Kinase Inhibitor Resistant Lung Adenocarcinoma Models.
Polonio-Alcalá E, Palomeras S, Torres-Oteros D, Relat J, Planas M, Feliu L, Ciurana J, Ruiz-Martínez S, Puig T
Cancers 2020 May 19;12(5)
Cancers 2020 May 19;12(5)
Bone-targeted lncRNA OGRU alleviates unloading-induced bone loss via miR-320-3p/Hoxa10 axis.
Wang K, Wang Y, Hu Z, Zhang L, Li G, Dang L, Tan Y, Cao X, Shi F, Zhang S, Zhang G
Cell death & disease 2020 May 19;11(5):382
Cell death & disease 2020 May 19;11(5):382
High-mobility group box 1 promotes epithelial-to-mesenchymal transition in crystalline silica induced pulmonary inflammation and fibrosis.
Ma J, Xu Y, Li W, Zhou Y, Wang D, Yang M, Wang B, Chen W
Toxicology letters 2020 May 17;330:134-143
Toxicology letters 2020 May 17;330:134-143
Knockdown of the Ribosomal Protein eL29 in Mammalian Cells Leads to Significant Changes in Gene Expression at the Transcription Level.
Gopanenko AV, Kolobova AV, Meschaninova MI, Venyaminova AG, Tupikin AE, Kabilov MR, Malygin AA, Karpova GG
Cells 2020 May 15;9(5)
Cells 2020 May 15;9(5)
TACC3 promotes prostate cancer cell proliferation and restrains primary cilium formation.
Qie Y, Wang L, Du E, Chen S, Lu C, Ding N, Yang K, Xu Y
Experimental cell research 2020 May 15;390(2):111952
Experimental cell research 2020 May 15;390(2):111952
Time serial transcriptome reveals Cyp2c29 as a key gene in hepatocellular carcinoma development.
Wang Q, Tang Q, Zhao L, Zhang Q, Wu Y, Hu H, Liu L, Liu X, Zhu Y, Guo A, Yang X
Cancer biology & medicine 2020 May 15;17(2):401-417
Cancer biology & medicine 2020 May 15;17(2):401-417
MEL endomorphins act as potent inflammatory analgesics with the inhibition of activated non-neuronal cells and modulation of pro-inflammatory cytokines.
Cui JM, Zhao L, Wang ZJ, Ma MT, Wang Y, Luo KY, Wang LQ, Wei S, Zhang XH, Han CZ, Liu X, Wang R
Neuropharmacology 2020 May 15;168:107992
Neuropharmacology 2020 May 15;168:107992
Heterogeneous nuclear ribonucleoprotein A3 controls mitotic progression of neural progenitors via interaction with cohesin.
Ou MY, Ju XC, Cai YJ, Sun XY, Wang JF, Fu XQ, Sun Q, Luo ZG
Development (Cambridge, England) 2020 May 15;147(10)
Development (Cambridge, England) 2020 May 15;147(10)
Quercetin alleviated H2 O2 -induced apoptosis and steroidogenic impairment in goat luteinized granulosa cells.
Li M, Xue Y, Yu H, Mao D
Journal of biochemical and molecular toxicology 2020 May 15;:e22527
Journal of biochemical and molecular toxicology 2020 May 15;:e22527
UBQLN2 Promotes the Production of Type I Interferon via the TBK1-IRF3 Pathway.
Chen T, Zhang W, Huang B, Chen X, Huang C
Cells 2020 May 13;9(5)
Cells 2020 May 13;9(5)
Membrane-Associated α-Tubulin Is Less Acetylated in Postmortem Prefrontal Cortex from Depressed Subjects Relative to Controls: Cytoskeletal Dynamics, HDAC6, and Depression.
Singh H, Chmura J, Bhaumik R, Pandey GN, Rasenick MM
The Journal of neuroscience : the official journal of the Society for Neuroscience 2020 May 13;40(20):4033-4041
The Journal of neuroscience : the official journal of the Society for Neuroscience 2020 May 13;40(20):4033-4041
Discovery of a novel third-generation EGFR inhibitor and identification of a potential combination strategy to overcome resistance.
Zhang T, Qu R, Chan S, Lai M, Tong L, Feng F, Chen H, Song T, Song P, Bai G, Liu Y, Wang Y, Li Y, Su Y, Shen Y, Sun Y, Chen Y, Geng M, Ding K, Ding J, Xie H
Molecular cancer 2020 May 13;19(1):90
Molecular cancer 2020 May 13;19(1):90
Evidence for Cytoprotective Effect of Carbon Monoxide Donor in the Development of Acute Esophagitis Leading to Acute Esophageal Epithelium Lesions.
Magierowska K, Bakalarz D, Wójcik D, Korbut E, Danielak A, Głowacka U, Pajdo R, Buszewicz G, Ginter G, Surmiak M, Kwiecień S, Chmura A, Magierowski M, Brzozowski T
Cells 2020 May 12;9(5)
Cells 2020 May 12;9(5)
EFEMP2 indicates assembly of M0 macrophage and more malignant phenotypes of glioma.
Huang L, Wang Z, Chang Y, Wang K, Kang X, Huang R, Zhang Y, Chen J, Zeng F, Wu F, Zhao Z, Li G, Huang H, Jiang T, Hu H
Aging 2020 May 12;12(9):8397-8412
Aging 2020 May 12;12(9):8397-8412
SETDB1 promotes the progression of colorectal cancer via epigenetically silencing p21 expression.
Cao N, Yu Y, Zhu H, Chen M, Chen P, Zhuo M, Mao Y, Li L, Zhao Q, Wu M, Ye M
Cell death & disease 2020 May 11;11(5):351
Cell death & disease 2020 May 11;11(5):351
POTEE promotes colorectal carcinoma progression via activating the Rac1/Cdc42 pathway.
Xu Q, Chen J, Peng M, Duan S, Hu Y, Guo D, Geng J, Zhou J
Experimental cell research 2020 May 1;390(1):111933
Experimental cell research 2020 May 1;390(1):111933
RNA-Seq Reveals Underlying Transcriptomic Mechanisms of Bone Marrow-Derived Mesenchymal Stem Cells in the Regulation of Microglia-Mediated Neuroinflammation After Subarachnoid Hemorrhage.
Zhang L, Guo K, Yin S, Peng J, Pang J, Ma N, Zhang X, Xie Y, Chen L, Jiang Y
Stem cells and development 2020 May 1;29(9):562-573
Stem cells and development 2020 May 1;29(9):562-573
Type 3 adenylyl cyclase in the main olfactory epithelium participates in depression-like and anxiety-like behaviours.
Liu X, Zhou Y, Li S, Yang D, Jiao M, Liu X, Wang Z
Journal of affective disorders 2020 May 1;268:28-38
Journal of affective disorders 2020 May 1;268:28-38
A modular biomimetic strategy for the synthesis of macrolide P-glycoprotein inhibitors via Rh-catalyzed C-H activation.
Chen L, Quan H, Xu Z, Wang H, Xia Y, Lou L, Yang W
Nature communications 2020 May 1;11(1):2151
Nature communications 2020 May 1;11(1):2151
Demethyleneberberine attenuates concanavalin A-induced autoimmune hepatitis in mice through inhibition of NF-κB and MAPK signaling.
Zhang M, Li Q, Zhou C, Zhao Y, Li R, Zhang Y
International immunopharmacology 2020 Mar;80:106137
International immunopharmacology 2020 Mar;80:106137
Downregulation of ubiquitin-specific protease 2 possesses prognostic and diagnostic value and promotes the clear cell renal cell carcinoma progression.
Meng X, Xiong Z, Xiao W, Yuan C, Wang C, Huang Y, Tong J, Shi J, Chen Z, Liu C, Xie K, Xiong H, Chen K, Yang H, Zhang X
Annals of translational medicine 2020 Mar;8(6):319
Annals of translational medicine 2020 Mar;8(6):319
Genome sequencing analysis of a family with a child displaying severe abdominal distention and recurrent hypoglycemia.
Liu J, Ding G, Zou K, Jiang Z, Zhang J, Lu Y, Pignata A, Venner E, Liu P, Liu Z, Wangler MF, Sun Z
Molecular genetics & genomic medicine 2020 Mar;8(3):e1130
Molecular genetics & genomic medicine 2020 Mar;8(3):e1130
Characterization of seminal plasma proteomic alterations associated with the IVF and rescue-ICSI pregnancy in assisted reproduction.
Liu X, Liu G, Zhu P, Wang Y, Wang J, Zhang W, Wang W, Li N, Wang X, Zhang C, Liu J, Shen X, Liu F
Andrology 2020 Mar;8(2):407-420
Andrology 2020 Mar;8(2):407-420
Mouse model of metformin-induced diarrhea.
Takemori H, Hamamoto A, Isogawa K, Ito M, Takagi M, Morino H, Miura T, Oshida K, Shibata T
BMJ open diabetes research & care 2020 Mar;8(1)
BMJ open diabetes research & care 2020 Mar;8(1)
Rosmarinic acid exerts an anticancer effect on osteosarcoma cells by inhibiting DJ-1 via regulation of the PTEN-PI3K-Akt signaling pathway.
Ma Z, Yang J, Yang Y, Wang X, Chen G, Shi A, Lu Y, Jia S, Kang X, Lu L
Phytomedicine : international journal of phytotherapy and phytopharmacology 2020 Mar;68:153186
Phytomedicine : international journal of phytotherapy and phytopharmacology 2020 Mar;68:153186
Elevated myocardial SORBS2 and the underlying implications in left ventricular noncompaction cardiomyopathy.
Li C, Liu F, Liu S, Pan H, Du H, Huang J, Xie Y, Li Y, Zhao R, Wei Y
EBioMedicine 2020 Mar;53:102695
EBioMedicine 2020 Mar;53:102695
Thymosinβ4 alleviates cholestatic liver fibrosis in mice through downregulating PDGF/PDGFR and TGFβ/Smad pathways.
Chen C, Li X, Wang L
Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 2020 Mar;52(3):324-330
Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 2020 Mar;52(3):324-330
MicroRNA‑137 suppresses the proliferation, migration and invasion of cholangiocarcinoma cells by targeting WNT2B.
Chen T, Lei S, Zeng Z, Pan S, Zhang J, Xue Y, Sun Y, Lan J, Xu S, Mao D, Guo B
International journal of molecular medicine 2020 Mar;45(3):886-896
International journal of molecular medicine 2020 Mar;45(3):886-896
Linc00261 inhibits metastasis and the WNT signaling pathway of pancreatic cancer by regulating a miR‑552‑5p/FOXO3 axis.
Chen T, Lei S, Zeng Z, Zhang J, Xue Y, Sun Y, Lan J, Xu S, Mao D, Guo B
Oncology reports 2020 Mar;43(3):930-942
Oncology reports 2020 Mar;43(3):930-942
Aurora B induces epithelial-mesenchymal transition by stabilizing Snail1 to promote basal-like breast cancer metastasis.
Zhang J, Lin X, Wu L, Huang JJ, Jiang WQ, Kipps TJ, Zhang S
Oncogene 2020 Mar;39(12):2550-2567
Oncogene 2020 Mar;39(12):2550-2567
The Wnt/β-catenin/VASP positive feedback loop drives cell proliferation and migration in breast cancer.
Li K, Zhang J, Tian Y, He Y, Xu X, Pan W, Gao Y, Chen F, Wei L
Oncogene 2020 Mar;39(11):2258-2274
Oncogene 2020 Mar;39(11):2258-2274
Dehydrocostus lactone inhibits NLRP3 inflammasome activation by blocking ASC oligomerization and prevents LPS-mediated inflammation in vivo.
Chen Y, Li R, Wang Z, Hou X, Wang C, Ai Y, Shi W, Zhan X, Wang JB, Xiao X, Bai Z, Sun H, Xu G
Cellular immunology 2020 Mar;349:104046
Cellular immunology 2020 Mar;349:104046
Identification of apoptosis-associated protein factors distinctly expressed in cigarette smoke condensate-exposed airway bronchial epithelial cells.
Lin BC, Li QY, Tian L, Liu HL, Liu XH, Shi Y, He C, Ding SS, Yan J, Li K, Bian LP, Lai WQ, Zhang W, Li X, Xi ZG
Journal of biochemical and molecular toxicology 2020 Mar;34(3):e22444
Journal of biochemical and molecular toxicology 2020 Mar;34(3):e22444
HUWE1 promotes EGFR ubiquitination and degradation to protect against renal tubulointerstitial fibrosis.
Zhu Q, Dong H, Bukhari AA, Zhao A, Li M, Sun Y, Zhang X, Cao C, Su D, Liang X
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Mar;34(3):4591-4601
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Mar;34(3):4591-4601
Upregulation of KSRP by miR-27b attenuates schistosomiasis-induced hepatic fibrosis by targeting TGF-β1.
Wang S, Li M, Zhao X, Wang H, Zhu J, Wang C, Zhou M, Dong H, Zhou R
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Mar;34(3):4120-4133
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Mar;34(3):4120-4133
Jmjd3 regulates inflammasome activation and aggravates DSS-induced colitis in mice.
Huang M, Wang Q, Long F, Di Y, Wang J, Zhun Zhu Y, Liu X
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Mar;34(3):4107-4119
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Mar;34(3):4107-4119
Inflammatory-sensitive CHI3L1 protects nucleus pulposus via AKT3 signaling during intervertebral disc degeneration.
Wang R, Xu C, Zhong H, Hu B, Wei L, Liu N, Zhang Y, Shi Q, Wang C, Qi M, Gu Y, Shen X, Tian Y, Liu Y, Cao P, Chen H, Yuan W
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Mar;34(3):3554-3569
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Mar;34(3):3554-3569
Do You Know the Details of Your PAX8 Antibody? Monoclonal PAX8 (MRQ-50) Is Not Expressed in a Series of 45 Medullary Thyroid Carcinomas.
Gucer H, Caliskan S, Kefeli M, Mete O
Endocrine pathology 2020 Mar;31(1):33-38
Endocrine pathology 2020 Mar;31(1):33-38
A serpin from the tick Rhipicephalus haemaphysaloides: Involvement in vitellogenesis.
Xu Z, Yan Y, Zhang H, Cao J, Zhou Y, Xu Q, Zhou J
Veterinary parasitology 2020 Mar;279:109064
Veterinary parasitology 2020 Mar;279:109064
Atlastin-1 modulates seizure activity and neuronal excitability.
Lu X, Yang M, Yang Y, Wang XF
CNS neuroscience & therapeutics 2020 Mar;26(3):385-393
CNS neuroscience & therapeutics 2020 Mar;26(3):385-393
Immunoproteasome subunit β5i regulates diet-induced atherosclerosis through altering MERTK-mediated efferocytosis in Apoe knockout mice.
Liao J, Xie Y, Lin Q, Yang X, An X, Xia Y, Du J, Wang F, Li HH
The Journal of pathology 2020 Mar;250(3):275-287
The Journal of pathology 2020 Mar;250(3):275-287
Rutin promotes osteogenic differentiation of periodontal ligament stem cells through the GPR30-mediated PI3K/AKT/mTOR signaling pathway.
Zhao B, Xiong Y, Zhang Y, Jia L, Zhang W, Xu X
Experimental biology and medicine (Maywood, N.J.) 2020 Mar;245(6):552-561
Experimental biology and medicine (Maywood, N.J.) 2020 Mar;245(6):552-561
Oxymatrine suppresses IL-1β-induced degradation of the nucleus pulposus cell and extracellular matrix through the TLR4/NF-κB signaling pathway.
Wei K, Dai J, Wang Z, Pei Y, Chen Y, Ding Y, Ding Q, Ahati P, Zhou X, Wang H, Fang H
Experimental biology and medicine (Maywood, N.J.) 2020 Mar;245(6):532-541
Experimental biology and medicine (Maywood, N.J.) 2020 Mar;245(6):532-541
Anti-ageing effects of red ginseng on female Drosophila melanogaster.
Hou W, Pei J, Wang Y, Zhang J, Zheng H, Cui R
Journal of cellular and molecular medicine 2020 Mar;24(6):3751-3755
Journal of cellular and molecular medicine 2020 Mar;24(6):3751-3755
MiR-133a alleviates renal injury caused by sepsis by targeting BNIP3L.
Qin LY, Wang MX, Zhang H
European review for medical and pharmacological sciences 2020 Mar;24(5):2632-2639
European review for medical and pharmacological sciences 2020 Mar;24(5):2632-2639
Dioscin inhibits the growth of human osteosarcoma by inducing G2/M-phase arrest, apoptosis, and GSDME-dependent cell death in vitro and in vivo.
Ding Q, Zhang W, Cheng C, Mo F, Chen L, Peng G, Cai X, Wang J, Yang S, Liu X
Journal of cellular physiology 2020 Mar;235(3):2911-2924
Journal of cellular physiology 2020 Mar;235(3):2911-2924
Autophagy inhibition via Becn1 downregulation improves the mesenchymal stem cells antifibrotic potential in experimental liver fibrosis.
Wang HY, Li C, Liu WH, Deng FM, Ma Y, Guo LN, Kong H, Hu KA, Liu Q, Wu J, Sun J, Liu YL
Journal of cellular physiology 2020 Mar;235(3):2722-2737
Journal of cellular physiology 2020 Mar;235(3):2722-2737
Decreasing New York esophageal squamous cell carcinoma 1 expression inhibits multiple myeloma growth and osteolytic lesions.
Li F, Zhao F, Li M, Pan M, Shi F, Xu H, Zheng D, Wang L, Dou J
Journal of cellular physiology 2020 Mar;235(3):2183-2194
Journal of cellular physiology 2020 Mar;235(3):2183-2194
Silencing of tumor-suppressive NR_023387 in renal cell carcinoma via promoter hypermethylation and HNF4A deficiency.
Zhou H, Guo L, Yao W, Shi R, Yu G, Xu H, Ye Z
Journal of cellular physiology 2020 Mar;235(3):2113-2128
Journal of cellular physiology 2020 Mar;235(3):2113-2128
Polystyrene nanoplastic induces ROS production and affects the MAPK-HIF-1/NFkB-mediated antioxidant system in Daphnia pulex.
Liu Z, Huang Y, Jiao Y, Chen Q, Wu D, Yu P, Li Y, Cai M, Zhao Y
Aquatic toxicology (Amsterdam, Netherlands) 2020 Mar;220:105420
Aquatic toxicology (Amsterdam, Netherlands) 2020 Mar;220:105420
The tacrolimus-induced glucose homeostasis imbalance in terms of the liver: From bench to bedside.
Ling Q, Huang H, Han Y, Zhang C, Zhang X, Chen K, Wu L, Tang R, Zheng Z, Zheng S, Li L, Wang B
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2020 Mar;20(3):701-713
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2020 Mar;20(3):701-713
miR-181a negatively modulates synaptic plasticity in hippocampal cultures and its inhibition rescues memory deficits in a mouse model of Alzheimer's disease.
Rodriguez-Ortiz CJ, Prieto GA, Martini AC, Forner S, Trujillo-Estrada L, LaFerla FM, Baglietto-Vargas D, Cotman CW, Kitazawa M
Aging cell 2020 Mar;19(3):e13118
Aging cell 2020 Mar;19(3):e13118
Ubiquitination of P53 by E3 ligase MKRN2 promotes melanoma cell proliferation.
Zhang Y, Cui N, Zheng G
Oncology letters 2020 Mar;19(3):1975-1984
Oncology letters 2020 Mar;19(3):1975-1984
MicroRNA-103a-3p potentiates chemoresistance to cisplatin in non-small cell lung carcinoma by targeting neurofibromatosis 1.
Zhu H, Yang J, Yang S
Experimental and therapeutic medicine 2020 Mar;19(3):1797-1805
Experimental and therapeutic medicine 2020 Mar;19(3):1797-1805
The functional role of the C-terminal tail of the human ribosomal protein uS19.
Bulygin K, Malygin A, Gopanenko A, Graifer D, Karpova G
Biochimica et biophysica acta. Gene regulatory mechanisms 2020 Mar;1863(3):194490
Biochimica et biophysica acta. Gene regulatory mechanisms 2020 Mar;1863(3):194490
A long noncoding RNA sensitizes genotoxic treatment by attenuating ATM activation and homologous recombination repair in cancers.
Zhao K, Wang X, Xue X, Li L, Hu Y
PLoS biology 2020 Mar;18(3):e3000666
PLoS biology 2020 Mar;18(3):e3000666
Hypericin attenuates nonalcoholic fatty liver disease and abnormal lipid metabolism via the PKA-mediated AMPK signaling pathway in vitro and in vivo.
Liang C, Li Y, Bai M, Huang Y, Yang H, Liu L, Wang S, Yu C, Song Z, Bao Y, Yi J, Sun L, Li Y
Pharmacological research 2020 Mar;153:104657
Pharmacological research 2020 Mar;153:104657
Synthesis of dual functional procaine-derived carbon dots for bioimaging and anticancer therapy.
Zhao X, Qi T, Yang M, Zhang W, Kong C, Hao M, Wang Y, Zhang H, Yang B, Yang J, Jiang J
Nanomedicine (London, England) 2020 Mar;15(7):677-689
Nanomedicine (London, England) 2020 Mar;15(7):677-689
Matrix mechanics and water permeation regulate extracellular vesicle transport.
Lenzini S, Bargi R, Chung G, Shin JW
Nature nanotechnology 2020 Mar;15(3):217-223
Nature nanotechnology 2020 Mar;15(3):217-223
A new abietane diterpenoid from Ajuga ovalifolia var. calantha induces human lung epithelial A549 cell apoptosis by inhibiting SHP2.
Liu DM, Cao ZX, Yan HL, Li W, Yang F, Zhao WJ, Diao QC, Tan YZ
Fitoterapia 2020 Mar;141:104484
Fitoterapia 2020 Mar;141:104484
LongShengZhi capsule inhibits doxorubicin-induced heart failure by anti-oxidative stress.
Xu S, Wang Y, Yu M, Wang D, Liang Y, Chen Y, Liao C, Xie Z, Zhao B, Han J, Duan Y, Yang X
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Mar;123:109803
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Mar;123:109803
DKC1 enhances angiogenesis by promoting HIF-1α transcription and facilitates metastasis in colorectal cancer.
Hou P, Shi P, Jiang T, Yin H, Chu S, Shi M, Bai J, Song J
British journal of cancer 2020 Mar;122(5):668-679
British journal of cancer 2020 Mar;122(5):668-679
IL1β inhibits differentiation of cementoblasts via microRNA-325-3p.
Wang Y, Li Y, Shao P, Wang L, Bao X, Hu M
Journal of cellular biochemistry 2020 Mar;121(3):2606-2617
Journal of cellular biochemistry 2020 Mar;121(3):2606-2617
G protein-coupled receptor kinase-2: A potential biomarker for early diabetic cardiomyopathy.
Lai S, Fu X, Yang S, Zhang S, Lin Q, Zhang M, Chen H
Journal of diabetes 2020 Mar;12(3):247-258
Journal of diabetes 2020 Mar;12(3):247-258
Cannabinoid receptor 1 knockout alleviates hepatic steatosis by downregulating perilipin 2.
Irungbam K, Churin Y, Matono T, Weglage J, Ocker M, Glebe D, Hardt M, Koeppel A, Roderfeld M, Roeb E
Laboratory investigation; a journal of technical methods and pathology 2020 Mar;100(3):454-465
Laboratory investigation; a journal of technical methods and pathology 2020 Mar;100(3):454-465
ETS2 promotes epithelial-to-mesenchymal transition in renal fibrosis by targeting JUNB transcription.
Yao F, Wang X, Cui ZK, Lan H, Ai X, Song Q, Chen Z, Yang J, Wu B, Bai X
Laboratory investigation; a journal of technical methods and pathology 2020 Mar;100(3):438-453
Laboratory investigation; a journal of technical methods and pathology 2020 Mar;100(3):438-453
MicroRNA-217-5p ameliorates endothelial cell apoptosis induced by ox-LDL by targeting CLIC4.
Zhang X, Wang Z, Li W, Huang R, Zheng D, Bi G
Nutrition, metabolism, and cardiovascular diseases : NMCD 2020 Mar 9;30(3):523-533
Nutrition, metabolism, and cardiovascular diseases : NMCD 2020 Mar 9;30(3):523-533
Melatonin Promotes the Proliferation of Chicken Sertoli Cells by Activating the ERK/Inhibin Alpha Subunit Signaling Pathway.
Xu K, Wang J, Liu H, Zhao J, Lu W
Molecules (Basel, Switzerland) 2020 Mar 9;25(5)
Molecules (Basel, Switzerland) 2020 Mar 9;25(5)
Molecular hydrogen attenuates methamphetamine-induced behavioral sensitization and activation of ERK-ΔFosB signaling in the mouse nucleus accumbens.
Wen D, Hui R, Liu Y, Luo Y, Wang J, Shen X, Xie B, Yu F, Cong B, Ma C
Progress in neuro-psychopharmacology & biological psychiatry 2020 Mar 8;97:109781
Progress in neuro-psychopharmacology & biological psychiatry 2020 Mar 8;97:109781
Topology, Antiviral Functional Residues and Mechanism of IFITM1.
Sun F, Xia Z, Han Y, Gao M, Wang L, Wu Y, Sabatier JM, Miao L, Cao Z
Viruses 2020 Mar 8;12(3)
Viruses 2020 Mar 8;12(3)
Novel HSP90-PI3K Dual Inhibitor Suppresses Melanoma Cell Proliferation by Interfering with HSP90-EGFR Interaction and Downstream Signaling Pathways.
Zhao Q, Zhu HP, Xie X, Mao Q, Liu YQ, He XH, Peng C, Jiang QL, Huang W
International journal of molecular sciences 2020 Mar 7;21(5)
International journal of molecular sciences 2020 Mar 7;21(5)
Transcription co-activator P300 activates Elk1-aPKC-ι signaling mediated epithelial-to-mesenchymal transition and malignancy in hepatocellular carcinoma.
Ma C, Huang S, Xu L, Tian L, Yang Y, Wang J
Oncogenesis 2020 Mar 6;9(3):32
Oncogenesis 2020 Mar 6;9(3):32
Anti-toll-like receptor 2 antibody ameliorates hepatic injury, inflammation, fibrosis and steatosis in obesity-related metabolic disorder rats via regulating MAPK and NF-κB pathways.
Wu L, Sun J, Liu L, Du X, Liu Y, Yan X, Kombo Osoro E, Zhang F, Feng L, Liang D, Li Y, Chen Q, Sun S, Zhang L, Lan X, Li D, Lu S
International immunopharmacology 2020 Mar 6;82:106368
International immunopharmacology 2020 Mar 6;82:106368
Pathway-specific enzymes from bamboo and crop leaves biosynthesize anti-nociceptive C-glycosylated flavones.
Sun Y, Chen Z, Yang J, Mutanda I, Li S, Zhang Q, Zhang Y, Zhang Y, Wang Y
Communications biology 2020 Mar 6;3(1):110
Communications biology 2020 Mar 6;3(1):110
Human polymorphisms in GSDMD alter the inflammatory response.
Rathkey JK, Xiao TS, Abbott DW
The Journal of biological chemistry 2020 Mar 6;295(10):3228-3238
The Journal of biological chemistry 2020 Mar 6;295(10):3228-3238
lncRNA RMST Suppressed GBM Cell Mitophagy through Enhancing FUS SUMOylation.
Liu C, Peng Z, Li P, Fu H, Feng J, Zhang Y, Liu T, Liu Y, Liu Q, Liu Q, Li D, Wu M
Molecular therapy. Nucleic acids 2020 Mar 6;19:1198-1208
Molecular therapy. Nucleic acids 2020 Mar 6;19:1198-1208
The 25(OH)D/VDR signaling may play a role in major depression.
He Y, Wu Z, Lan T, Wang Y, Tian Y, Chen X, Li Y, Bai M, Liu J, Gong X, Cheng K, Xie P
Biochemical and biophysical research communications 2020 Mar 5;523(2):405-410
Biochemical and biophysical research communications 2020 Mar 5;523(2):405-410
TRPC6-dependent Ca2+ signaling mediates airway inflammation in response to oxidative stress via ERK pathway.
Chen Q, Zhou Y, Zhou L, Fu Z, Yang C, Zhao L, Li S, Chen Y, Wu Y, Ling Z, Wang Y, Huang J, Li J
Cell death & disease 2020 Mar 5;11(3):170
Cell death & disease 2020 Mar 5;11(3):170
PTEN inhibitor VO-OHpic attenuates GC-associated endothelial progenitor cell dysfunction and osteonecrosis of the femoral head via activating Nrf2 signaling and inhibiting mitochondrial apoptosis pathway.
Yao X, Yu S, Jing X, Guo J, Sun K, Guo F, Ye Y
Stem cell research & therapy 2020 Mar 30;11(1):140
Stem cell research & therapy 2020 Mar 30;11(1):140
Genetic inactivation of mTORC1 or mTORC2 in neurons reveals distinct functions in glutamatergic synaptic transmission.
McCabe MP, Cullen ER, Barrows CM, Shore AN, Tooke KI, Laprade KA, Stafford JM, Weston MC
eLife 2020 Mar 3;9
eLife 2020 Mar 3;9
5-HT1AR alleviates Aβ-induced cognitive decline and neuroinflammation through crosstalk with NF-κB pathway in mice.
Wang M, Zong HF, Chang KW, Han H, Yasir Rizvi M, Iffat Neha S, Li ZY, Yang WN, Qian YH
International immunopharmacology 2020 Mar 3;82:106354
International immunopharmacology 2020 Mar 3;82:106354
Nanofiber Alignment Mediates the Pattern of Single Cell Migration.
Wang Y, Yao Y
Langmuir : the ACS journal of surfaces and colloids 2020 Mar 3;36(8):2129-2135
Langmuir : the ACS journal of surfaces and colloids 2020 Mar 3;36(8):2129-2135
Qingyi decoction protects against myocardial injuries induced by severe acute pancreatitis.
Li L, Li YQ, Sun ZW, Xu CM, Wu J, Liu GL, Bakheet AM, Chen HL
World journal of gastroenterology 2020 Mar 28;26(12):1317-1328
World journal of gastroenterology 2020 Mar 28;26(12):1317-1328
The Agpat4/LPA axis in colorectal cancer cells regulates antitumor responses via p38/p65 signaling in macrophages.
Zhang D, Shi R, Xiang W, Kang X, Tang B, Li C, Gao L, Zhang X, Zhang L, Dai R, Miao H
Signal transduction and targeted therapy 2020 Mar 27;5(1):24
Signal transduction and targeted therapy 2020 Mar 27;5(1):24
Long non-coding RNA HAL suppresses the migration and invasion of serous ovarian cancer by inhibiting EMT signaling pathway.
Wu K, Li L, Li L, Wang D
Bioscience reports 2020 Mar 27;40(3)
Bioscience reports 2020 Mar 27;40(3)
Posttranslational lysine 2-hydroxyisobutyrylation of human sperm tail proteins affects motility.
Cheng YM, Peng Z, Chen HY, Pan TT, Hu XN, Wang F, Luo T
Human reproduction (Oxford, England) 2020 Mar 27;35(3):494-503
Human reproduction (Oxford, England) 2020 Mar 27;35(3):494-503
The C-terminal domain of feline and bovine SAMHD1 proteins has a crucial role in lentiviral restriction.
Wang C, Zhang K, Meng L, Zhang X, Song Y, Zhang Y, Gai Y, Zhang Y, Yu B, Wu J, Wang S, Yu X
The Journal of biological chemistry 2020 Mar 27;295(13):4252-4264
The Journal of biological chemistry 2020 Mar 27;295(13):4252-4264
Design, Synthesis, and Biological Evaluation of Imidazo[1,2-a]pyridine Derivatives as Novel PI3K/mTOR Dual Inhibitors.
Yu Y, Han Y, Zhang F, Gao Z, Zhu T, Dong S, Ma M
Journal of medicinal chemistry 2020 Mar 26;63(6):3028-3046
Journal of medicinal chemistry 2020 Mar 26;63(6):3028-3046
Changed PGA and POSTN levels in choroid plexus are associated with depressive-like behaviors in mice.
Liu J, He Y, Cheng K, Xie P
Biochemical and biophysical research communications 2020 Mar 26;524(1):231-235
Biochemical and biophysical research communications 2020 Mar 26;524(1):231-235
KLF5 Is Crucial for Androgen-AR Signaling to Transactivate Genes and Promote Cell Proliferation in Prostate Cancer Cells.
Li J, Zhang B, Liu M, Fu X, Ci X, A J, Fu C, Dong G, Wu R, Zhang Z, Fu L, Dong JT
Cancers 2020 Mar 21;12(3)
Cancers 2020 Mar 21;12(3)
Dual regulation of p53 by the ribosome maturation factor SBDS.
Hao Q, Wang J, Chen Y, Wang S, Cao M, Lu H, Zhou X
Cell death & disease 2020 Mar 20;11(3):197
Cell death & disease 2020 Mar 20;11(3):197
Cervical carcinoma risk associate with genetic polymorphisms of NEIL2 gene in Chinese population and its significance as predictive biomarker.
Ye F, Liu J, Wang H, Chen X, Cheng Q, Chen H
Scientific reports 2020 Mar 20;10(1):5136
Scientific reports 2020 Mar 20;10(1):5136
Inhibiting both proline biosynthesis and lipogenesis synergistically suppresses tumor growth.
Liu M, Wang Y, Yang C, Ruan Y, Bai C, Chu Q, Cui Y, Chen C, Ying G, Li B
The Journal of experimental medicine 2020 Mar 2;217(3)
The Journal of experimental medicine 2020 Mar 2;217(3)
Complement Signals Determine Opposite Effects of B Cells in Chemotherapy-Induced Immunity.
Lu Y, Zhao Q, Liao JY, Song E, Xia Q, Pan J, Li Y, Li J, Zhou B, Ye Y, Di C, Yu S, Zeng Y, Su S
Cell 2020 Mar 19;180(6):1081-1097.e24
Cell 2020 Mar 19;180(6):1081-1097.e24
AQP1 modulates tendon stem/progenitor cells senescence during tendon aging.
Chen M, Li Y, Xiao L, Dai G, Lu P, Wang Y, Rui Y
Cell death & disease 2020 Mar 18;11(3):193
Cell death & disease 2020 Mar 18;11(3):193
ADORA1 Inhibition Promotes Tumor Immune Evasion by Regulating the ATF3-PD-L1 Axis.
Liu H, Kuang X, Zhang Y, Ye Y, Li J, Liang L, Xie Z, Weng L, Guo J, Li H, Ma F, Chen X, Zhao S, Su J, Yang N, Fang F, Xie Y, Tao J, Zhang J, Chen M, Peng C, Sun L, Zhang X, Liu J, Han L, Xu X, Hung MC, Chen X
Cancer cell 2020 Mar 16;37(3):324-339.e8
Cancer cell 2020 Mar 16;37(3):324-339.e8
PHLDA1 is a new therapeutic target of oxidative stress and ischemia reperfusion-induced myocardial injury.
Guo Y, Jia P, Chen Y, Yu H, Xin X, Bao Y, Yang H, Wu N, Sun Y, Jia D
Life sciences 2020 Mar 15;245:117347
Life sciences 2020 Mar 15;245:117347
Design, synthesis, biological evaluation of 6-(2-amino-1H-benzo[d]imidazole-6-yl)quinazolin-4(3H)-one derivatives as novel anticancer agents with Aurora kinase inhibition.
Fan C, Zhong T, Yang H, Yang Y, Wang D, Yang X, Xu Y, Fan Y
European journal of medicinal chemistry 2020 Mar 15;190:112108
European journal of medicinal chemistry 2020 Mar 15;190:112108
Mesencephalic astrocyte-derived neurotrophic factor ameliorates steatosis in HepG2 cells by regulating hepatic lipid metabolism.
He M, Wang C, Long XH, Peng JJ, Liu DF, Yang GY, Jensen MD, Zhang LL
World journal of gastroenterology 2020 Mar 14;26(10):1029-1041
World journal of gastroenterology 2020 Mar 14;26(10):1029-1041
Pellino1 regulates neuropathic pain as well as microglial activation through the regulation of MAPK/NF-κB signaling in the spinal cord.
Wang L, Yin C, Liu T, Abdul M, Zhou Y, Cao JL, Lu C
Journal of neuroinflammation 2020 Mar 14;17(1):83
Journal of neuroinflammation 2020 Mar 14;17(1):83
Western diet induces severe nonalcoholic steatohepatitis, ductular reaction, and hepatic fibrosis in liver CGI-58 knockout mice.
Yang P, Wang Y, Tang W, Sun W, Ma Y, Lin S, Jing J, Jiang L, Shi H, Song Z, Yu L
Scientific reports 2020 Mar 13;10(1):4701
Scientific reports 2020 Mar 13;10(1):4701
Dietary Compound Isoliquiritigenin, an Antioxidant from Licorice, Suppresses Triple-Negative Breast Tumor Growth via Apoptotic Death Program Activation in Cell and Xenograft Animal Models.
Lin PH, Chiang YF, Shieh TM, Chen HY, Shih CK, Wang TH, Wang KL, Huang TC, Hong YH, Li SC, Hsia SM
Antioxidants (Basel, Switzerland) 2020 Mar 10;9(3)
Antioxidants (Basel, Switzerland) 2020 Mar 10;9(3)
Controlled release of adenosine from core-shell nanofibers to promote bone regeneration through STAT3 signaling pathway.
Cheng X, Cheng G, Xing X, Yin C, Cheng Y, Zhou X, Jiang S, Tao F, Deng H, Li Z
Journal of controlled release : official journal of the Controlled Release Society 2020 Mar 10;319:234-245
Journal of controlled release : official journal of the Controlled Release Society 2020 Mar 10;319:234-245
LncRNA HCP5 promotes cell proliferation and inhibits apoptosis via miR-27a-3p/IGF-1 axis in human granulosa-like tumor cell line KGN.
Chen Y, Zhang X, An Y, Liu B, Lu M
Molecular and cellular endocrinology 2020 Mar 1;503:110697
Molecular and cellular endocrinology 2020 Mar 1;503:110697
AEBP1 Promotes the Occurrence and Development of Abdominal Aortic Aneurysm by Modulating Inflammation via the NF-κB Pathway.
Ren J, Han Y, Ren T, Fang H, Xu X, Lun Y, Jiang H, Xin S, Zhang J
Journal of atherosclerosis and thrombosis 2020 Mar 1;27(3):255-270
Journal of atherosclerosis and thrombosis 2020 Mar 1;27(3):255-270
Microcystins-LR induced apoptosis via S-nitrosylation of GAPDH in colorectal cancer cells.
Li K, Huang M, Xu P, Wang M, Ye S, Wang Q, Zeng S, Chen X, Gao W, Chen J, Zhang Q, Zhong Z, Sun Y, Liu Q
Ecotoxicology and environmental safety 2020 Mar 1;190:110096
Ecotoxicology and environmental safety 2020 Mar 1;190:110096
miR-144 Mediates High Fat-Induced Changes of Cholesterol Metabolism via Direct Regulation of C/EBPα in the Liver and Isolated Hepatocytes of Yellow Catfish.
Chen G, Wu K, Zhao T, Ling S, Liu W, Luo Z
The Journal of nutrition 2020 Mar 1;150(3):464-474
The Journal of nutrition 2020 Mar 1;150(3):464-474
Suppression of high-mobility group box 1 ameliorates xerostomia in a Sjögren syndrome-triggered mouse model.
Wang D, Zhou M, Wang Y, Sun S
Canadian journal of physiology and pharmacology 2020 Jun;98(6):351-356
Canadian journal of physiology and pharmacology 2020 Jun;98(6):351-356
Nbr1-regulated autophagy in Lactoferrin-induced osteoblastic differentiation.
Zhang Y, Zhang ZN, Li N, Zhao LJ, Xue Y, Wu HJ, Hou JM
Bioscience, biotechnology, and biochemistry 2020 Jun;84(6):1191-1200
Bioscience, biotechnology, and biochemistry 2020 Jun;84(6):1191-1200
Antibody microarray analysis of serum inflammatory cytokines in patients with calcific aortic valve disease.
Fu B, Zhang Y, Chen Q, Guo Z, Jiang N
Annals of translational medicine 2020 Jun;8(12):761
Annals of translational medicine 2020 Jun;8(12):761
Fam83d modulates MAP kinase and AKT signaling and is induced during neurogenic skeletal muscle atrophy.
Cooper LM, Hanson A, Kavanagh JA, Waddell DS
Cellular signalling 2020 Jun;70:109576
Cellular signalling 2020 Jun;70:109576
Expression, location and biological effects of four and a half LIM domain protein 2 (FHL2) on granulosa cells in ovine.
Zhang L, Li R, Chen L, Xing Z, Song Y, Nie X, Wang L, Han H, Liu A, Ma X, Ma RZ, Tian S
Reproduction in domestic animals = Zuchthygiene 2020 Jun;55(6):737-746
Reproduction in domestic animals = Zuchthygiene 2020 Jun;55(6):737-746
TNF-α/HMGB1 inflammation signalling pathway regulates pyroptosis during liver failure and acute kidney injury.
Wang Y, Zhang H, Chen Q, Jiao F, Shi C, Pei M, Lv J, Zhang H, Wang L, Gong Z
Cell proliferation 2020 Jun;53(6):e12829
Cell proliferation 2020 Jun;53(6):e12829
TGM3 promotes epithelial-mesenchymal transition and hepatocellular carcinogenesis and predicts poor prognosis for patients after curative resection.
Hu JW, Yang ZF, Li J, Hu B, Luo CB, Zhu K, Dai Z, Cai JB, Zhan H, Hu ZQ, Hu J, Cao Y, Qiu SJ, Zhou J, Fan J, Huang XW
Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 2020 Jun;52(6):668-676
Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 2020 Jun;52(6):668-676
Enhanced tenogenic differentiation and tendon-like tissue formation by Scleraxis overexpression in human amniotic mesenchymal stem cells.
Zhu X, Liu Z, Wu S, Li Y, Xiong H, Zou G, Jin Y, Yang J, You Q, Zhang J, Liu Y
Journal of molecular histology 2020 Jun;51(3):209-220
Journal of molecular histology 2020 Jun;51(3):209-220
Effects of hyperoxia exposure on the expression of Nrf2 and heme oxygenase-1 in lung tissues of premature rats.
Chu X, Zhang X, Gong X, Zhou H, Cai C
Molecular and cellular probes 2020 Jun;51:101529
Molecular and cellular probes 2020 Jun;51:101529
EMT related circular RNA expression profiles identify circSCYL2 as a novel molecule in breast tumor metastasis.
Yuan C, Luo X, Zhan X, Zeng H, Duan S
International journal of molecular medicine 2020 Jun;45(6):1697-1710
International journal of molecular medicine 2020 Jun;45(6):1697-1710
Alda-1, an Aldehyde Dehydrogenase 2 Agonist, Improves Cutaneous Wound Healing by Activating Epidermal Keratinocytes via Akt/GSK-3β/β-Catenin Pathway.
Zhang S, Chen C, Ying J, Wei C, Wang L, Yang Z, Qi F
Aesthetic plastic surgery 2020 Jun;44(3):993-1005
Aesthetic plastic surgery 2020 Jun;44(3):993-1005
Leucine-rich repeat containing 4 act as an autophagy inhibitor that restores sensitivity of glioblastoma to temozolomide.
Feng J, Zhang Y, Ren X, Li D, Fu H, Liu C, Zhou W, Liu Q, Liu Q, Wu M
Oncogene 2020 Jun;39(23):4551-4566
Oncogene 2020 Jun;39(23):4551-4566
Altered expression of AKT1 and P38A in the colons of patients with Hirschsprung's disease.
Wu L, Xiao P, Li Q, Zhang Z, Wang H, Jiang Q, Li L
Pediatric surgery international 2020 Jun;36(6):719-725
Pediatric surgery international 2020 Jun;36(6):719-725
Ghrelin promotes neural differentiation of adipose tissue-derived mesenchymal stem cell via AKT/mTOR and β-catenin signaling pathways.
Liu GB, Pan YM, Liu YS, Hu JH, Zhang XD, Zhang DW, Wang Y, Feng YK, Yu JB, Cheng YX
The Kaohsiung journal of medical sciences 2020 Jun;36(6):405-416
The Kaohsiung journal of medical sciences 2020 Jun;36(6):405-416
Berardinelli-Seip congenital lipodystrophy 2/SEIPIN determines brown adipose tissue maintenance and thermogenic programing.
Zhou H, Xu C, Lee H, Yoon Y, Chen W
Molecular metabolism 2020 Jun;36:100971
Molecular metabolism 2020 Jun;36:100971
Neuroprotective effects of miR-532-5p against ischemic stroke.
Mu J, Cheng X, Zhong S, Chen X, Zhao C
Metabolic brain disease 2020 Jun;35(5):753-763
Metabolic brain disease 2020 Jun;35(5):753-763
Upregulation of miR-219a-5p Decreases Cerebral Ischemia/Reperfusion Injury In Vitro by Targeting Pde4d.
Lu MY, Wu JR, Liang RB, Wang YP, Zhu YC, Ma ZT, Zhang H, Zan J, Tan W
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association 2020 Jun;29(6):104801
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association 2020 Jun;29(6):104801
Integrin β3, a RACK1 interacting protein, is critical for porcine reproductive and respiratory syndrome virus infection and NF-κB activation in Marc-145 cells.
Yang C, Lan R, Wang X, Zhao Q, Li X, Bi J, Wang J, Yang G, Lin Y, Liu J, Yin G
Virus research 2020 Jun;282:197956
Virus research 2020 Jun;282:197956
The E3 ubiquitin ligase TRIM7 suppressed hepatocellular carcinoma progression by directly targeting Src protein.
Zhu L, Qin C, Li T, Ma X, Qiu Y, Lin Y, Ma D, Qin Z, Sun C, Shen X, Zhao Y, Han L
Cell death and differentiation 2020 Jun;27(6):1819-1831
Cell death and differentiation 2020 Jun;27(6):1819-1831
Inflammatory injury and mitophagy induced by Cr(VI) in chicken liver.
Wang Y, Hao J, Zhang S, Li L, Wang R, Zhu Y, Liu Y, Liu J
Environmental science and pollution research international 2020 Jun;27(18):22980-22988
Environmental science and pollution research international 2020 Jun;27(18):22980-22988
Knockdown of p66ShcA activates Nrf2 pathway to protect cardiomyocytes from oxidative stress and inflammation induced by H2O2.
Liu B, Jia N, Wei HL, Lan M, Liu JM, Xue YZ
European review for medical and pharmacological sciences 2020 Jun;24(12):6994-7001
European review for medical and pharmacological sciences 2020 Jun;24(12):6994-7001
MiR-126 regulated myocardial autophagy on myocardial infarction.
Shi CC, Pan LY, Peng ZY, Li JG
European review for medical and pharmacological sciences 2020 Jun;24(12):6971-6979
European review for medical and pharmacological sciences 2020 Jun;24(12):6971-6979
Seizure-induced impairment in neuronal ketogenesis: Role of zinc-α2-glycoprotein in mitochondria.
Tan C, Liu X, Peng W, Wang H, Zhou W, Jiang J, Wei X, Mo L, Chen Y, Chen L
Journal of cellular and molecular medicine 2020 Jun;24(12):6833-6845
Journal of cellular and molecular medicine 2020 Jun;24(12):6833-6845
Endogenous thrombopoietin promotes non-small-cell lung carcinoma cell proliferation and migration by regulating EGFR signalling.
Zou Z, Fan X, Liu Y, Sun Y, Zhang X, Sun G, Li X, Xu S
Journal of cellular and molecular medicine 2020 Jun;24(12):6644-6657
Journal of cellular and molecular medicine 2020 Jun;24(12):6644-6657
A study of the effects of SGLT-2 inhibitors on diabetic cardiomyopathy through miR-30d/KLF9/VEGFA pathway.
Zhang WY, Wang J, Li AZ
European review for medical and pharmacological sciences 2020 Jun;24(11):6346-6359
European review for medical and pharmacological sciences 2020 Jun;24(11):6346-6359
Analysis of deep sequencing exosome-microRNA expression profile derived from CP-II reveals potential role of gga-miRNA-451 in inflammation.
Zhao Y, Fu Y, Zou M, Sun Y, Yin X, Niu L, Gong Y, Peng X
Journal of cellular and molecular medicine 2020 Jun;24(11):6178-6190
Journal of cellular and molecular medicine 2020 Jun;24(11):6178-6190
An upstream open reading frame regulates vasculogenic mimicry of glioma via ZNRD1-AS1/miR-499a-5p/ELF1/EMI1 pathway.
Wang M, Yang C, Liu X, Zheng J, Xue Y, Ruan X, Shen S, Wang D, Li Z, Cai H, Liu Y
Journal of cellular and molecular medicine 2020 Jun;24(11):6120-6136
Journal of cellular and molecular medicine 2020 Jun;24(11):6120-6136
Rice Protein Exerts Endogenous Antioxidant Capacity via Methionine Sulfoxide Reductase and the Nrf2 Antioxidant System Independent of Age.
Li H, Liang M, Wang Z, Zhang Y, Wu Q, Yang L
Journal of medicinal food 2020 Jun;23(6):565-574
Journal of medicinal food 2020 Jun;23(6):565-574
BMP4 resets mouse epiblast stem cells to naive pluripotency through ZBTB7A/B-mediated chromatin remodelling.
Yu S, Zhou C, Cao S, He J, Cai B, Wu K, Qin Y, Huang X, Xiao L, Ye J, Xu S, Xie W, Kuang J, Chu S, Guo J, Liu H, Pang W, Guo L, Zeng M, Wang X, Luo R, Li C, Zhao G, Wang B, Wu L, Chen J, Liu J, Pei D
Nature cell biology 2020 Jun;22(6):651-662
Nature cell biology 2020 Jun;22(6):651-662
MicroRNA‑28 promotes the proliferation of non‑small‑cell lung cancer cells by targeting PTEN.
Cui F, Zhou Q, Xiao K, Qian H
Molecular medicine reports 2020 Jun;21(6):2589-2596
Molecular medicine reports 2020 Jun;21(6):2589-2596
Bisphenol a affects endometrial stromal cells decidualization, involvement of epigenetic regulation.
Xiong Y, Wen X, Liu H, Zhang M, Zhang Y
The Journal of steroid biochemistry and molecular biology 2020 Jun;200:105640
The Journal of steroid biochemistry and molecular biology 2020 Jun;200:105640
Biointerface anisotropy modulates migration of breast cancer cell.
Dai J, Wang Y, Gong J, Yao Y
Colloids and surfaces. B, Biointerfaces 2020 Jun;190:110973
Colloids and surfaces. B, Biointerfaces 2020 Jun;190:110973
PTPN3 Inhibits the Growth and Metastasis of Clear Cell Renal Cell Carcinoma via Inhibition of PI3K/AKT Signaling.
Peng XS, Yang JP, Qiang YY, Sun R, Cao Y, Zheng LS, Peng LX, Lang YH, Mei Y, Li CZ, Meng DF, Liu ZJ, Wang MD, Zhou FJ, Huang BJ, Qian CN
Molecular cancer research : MCR 2020 Jun;18(6):903-912
Molecular cancer research : MCR 2020 Jun;18(6):903-912
Meprin-α (Mep1A) enhances TNF-α secretion by mast cells and aggravates abdominal aortic aneurysms.
Gao R, Liu D, Guo W, Ge W, Fan T, Li B, Gao P, Liu B, Zheng Y, Wang J
British journal of pharmacology 2020 Jun;177(12):2872-2885
British journal of pharmacology 2020 Jun;177(12):2872-2885
DHA attenuates Aβ-induced necroptosis through the RIPK1/RIPK3 signaling pathway in THP-1 monocytes.
Yuan S, Li H, Yang C, Xie W, Wang Y, Zhang J, Cai Z, Mao Z, Xie W, Lü T
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Jun;126:110102
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Jun;126:110102
Modified citrus pectin ameliorates myocardial fibrosis and inflammation via suppressing galectin-3 and TLR4/MyD88/NF-κB signaling pathway.
Xu GR, Zhang C, Yang HX, Sun JH, Zhang Y, Yao TT, Li Y, Ruan L, An R, Li AY
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Jun;126:110071
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Jun;126:110071
Interference with SMO increases chemotherapy drug sensitivity of A2780/DDP cells by inhibiting the Hh/Gli signaling pathway.
Ma S, Liu D, Tan W, Du B, Liu W, Li W, Jiao Y
Journal of cellular biochemistry 2020 Jun;121(5-6):3256-3265
Journal of cellular biochemistry 2020 Jun;121(5-6):3256-3265
Long noncoding RNA linc00467 plays an oncogenic role in hepatocellular carcinoma by regulating the miR-18a-5p/NEDD9 axis.
Zheng Y, Nie P, Xu S
Journal of cellular biochemistry 2020 Jun;121(5-6):3135-3144
Journal of cellular biochemistry 2020 Jun;121(5-6):3135-3144
Activator of thyroid and retinoid receptor increases sorafenib resistance in hepatocellular carcinoma by facilitating the Warburg effect.
Ma L, Liu W, Xu A, Ji Q, Ma Y, Tai Y, Wang Y, Shen C, Liu Y, Wang T, Han J, Zhao C
Cancer science 2020 Jun;111(6):2028-2040
Cancer science 2020 Jun;111(6):2028-2040
Oxidative stress induces monocyte-to-myofibroblast transdifferentiation through p38 in pancreatic ductal adenocarcinoma.
Huang X, He C, Hua X, Kan A, Mao Y, Sun S, Duan F, Wang J, Huang P, Li S
Clinical and translational medicine 2020 Jun;10(2):e41
Clinical and translational medicine 2020 Jun;10(2):e41
T-cell activation and immune memory enhancement induced by irreversible electroporation in pancreatic cancer.
He C, Huang X, Zhang Y, Lin X, Li S
Clinical and translational medicine 2020 Jun;10(2):e39
Clinical and translational medicine 2020 Jun;10(2):e39
The effect of swimming exercise and diet on the hypothalamic inflammation of ApoE-/- mice based on SIRT1-NF-κB-GnRH expression.
Wang X, Yang J, Lu T, Zhan Z, Wei W, Lyu X, Jiang Y, Xue X
Aging 2020 Jun 9;12(11):11085-11099
Aging 2020 Jun 9;12(11):11085-11099
Highly expressed STAT1 contributes to the suppression of stemness properties in human paclitaxel-resistant ovarian cancer cells.
Wang F, Zhang L, Liu J, Zhang J, Xu G
Aging 2020 Jun 9;12(11):11042-11060
Aging 2020 Jun 9;12(11):11042-11060
Gan Shen Fu Fang ameliorates liver fibrosis in vitro and in vivo by inhibiting the inflammatory response and extracellular signal-regulated kinase phosphorylation.
Du QH, Zhang CJ, Li WH, Mu Y, Xu Y, Lowe S, Han L, Yu X, Wang SY, Li Y, Li J
World journal of gastroenterology 2020 Jun 7;26(21):2810-2820
World journal of gastroenterology 2020 Jun 7;26(21):2810-2820
Progranulin inhibits LPS-induced macrophage M1 polarization via NF-кB and MAPK pathways.
Liu L, Guo H, Song A, Huang J, Zhang Y, Jin S, Li S, Zhang L, Yang C, Yang P
BMC immunology 2020 Jun 5;21(1):32
BMC immunology 2020 Jun 5;21(1):32
Role of ANKHD1/LINC00346/ZNF655 Feedback Loop in Regulating the Glioma Angiogenesis via Staufen1-Mediated mRNA Decay.
Yang C, Zheng J, Liu X, Xue Y, He Q, Dong Y, Wang D, Li Z, Liu L, Ma J, Cai H, Liu Y
Molecular therapy. Nucleic acids 2020 Jun 5;20:866-878
Molecular therapy. Nucleic acids 2020 Jun 5;20:866-878
lncRNA LINC00665 Stabilized by TAF15 Impeded the Malignant Biological Behaviors of Glioma Cells via STAU1-Mediated mRNA Degradation.
Ruan X, Zheng J, Liu X, Liu Y, Liu L, Ma J, He Q, Yang C, Wang D, Cai H, Li Z, Liu J, Xue Y
Molecular therapy. Nucleic acids 2020 Jun 5;20:823-840
Molecular therapy. Nucleic acids 2020 Jun 5;20:823-840
Minocycline alleviates NLRP3 inflammasome-dependent pyroptosis in monosodium glutamate-induced depressive rats.
Yang F, Zhu W, Cai X, Zhang W, Yu Z, Li X, Zhang J, Cai M, Xiang J, Cai D
Biochemical and biophysical research communications 2020 Jun 4;526(3):553-559
Biochemical and biophysical research communications 2020 Jun 4;526(3):553-559
Loss of CHCHD2 and CHCHD10 activates OMA1 peptidase to disrupt mitochondrial cristae phenocopying patient mutations.
Liu YT, Huang X, Nguyen D, Shammas MK, Wu BP, Dombi E, Springer DA, Poulton J, Sekine S, Narendra DP
Human molecular genetics 2020 Jun 3;29(9):1547-1567
Human molecular genetics 2020 Jun 3;29(9):1547-1567
Integrative Analysis of NSCLC Identifies LINC01234 as an Oncogenic lncRNA that Interacts with HNRNPA2B1 and Regulates miR-106b Biogenesis.
Chen Z, Chen X, Lei T, Gu Y, Gu J, Huang J, Lu B, Yuan L, Sun M, Wang Z
Molecular therapy : the journal of the American Society of Gene Therapy 2020 Jun 3;28(6):1479-1493
Molecular therapy : the journal of the American Society of Gene Therapy 2020 Jun 3;28(6):1479-1493
SRSF10 inhibits biogenesis of circ-ATXN1 to regulate glioma angiogenesis via miR-526b-3p/MMP2 pathway.
Liu X, Shen S, Zhu L, Su R, Zheng J, Ruan X, Shao L, Wang D, Yang C, Liu Y
Journal of experimental & clinical cancer research : CR 2020 Jun 29;39(1):121
Journal of experimental & clinical cancer research : CR 2020 Jun 29;39(1):121
Deletion of the Impg2 gene causes the degeneration of rod and cone cells in mice.
Xu H, Qu C, Gan L, Sun K, Tan J, Liu X, Jiang Z, Tian W, Liu W, Zhang S, Yang Y, Jiang L, Zhu X, Zhang L
Human molecular genetics 2020 Jun 27;29(10):1624-1634
Human molecular genetics 2020 Jun 27;29(10):1624-1634
Pyrroloquinoline Quinone Inhibits Oxidative Stress in Rats with Diabetic Nephropathy.
Zhang M, Zhang J, Xiong Y, Peng J, Wu X
Medical science monitor : international medical journal of experimental and clinical research 2020 Jun 27;26:e924372
Medical science monitor : international medical journal of experimental and clinical research 2020 Jun 27;26:e924372
Cimifugin ameliorates imiquimod-induced psoriasis by inhibiting oxidative stress and inflammation via NF-κB/MAPK pathway.
Liu A, Zhao W, Zhang B, Tu Y, Wang Q, Li J
Bioscience reports 2020 Jun 26;40(6)
Bioscience reports 2020 Jun 26;40(6)
STEAP1 facilitates metastasis and epithelial-mesenchymal transition of lung adenocarcinoma via the JAK2/STAT3 signaling pathway.
Huo SF, Shang WL, Yu M, Ren XP, Wen HX, Chai CY, Sun L, Hui K, Liu LH, Wei SH, Wang XX, Wang Y, Tian YX
Bioscience reports 2020 Jun 26;40(6)
Bioscience reports 2020 Jun 26;40(6)
Chi-miR-30b-5p inhibits dermal papilla cells proliferation by targeting CaMKIIδ gene in cashmere goat.
Zhang Y, Xia S, Wang T, Wang S, Yuan D, Li F, Wang X
BMC genomics 2020 Jun 26;21(1):430
BMC genomics 2020 Jun 26;21(1):430
The PABPC5/HCG15/ZNF331 Feedback Loop Regulates Vasculogenic Mimicry of Glioma via STAU1-Mediated mRNA Decay.
Jing F, Ruan X, Liu X, Yang C, Wang D, Zheng J, Xue Y, Shen S, Shao L, Yang Y, Wang P, Ma J, Liu Y
Molecular therapy oncolytics 2020 Jun 26;17:216-231
Molecular therapy oncolytics 2020 Jun 26;17:216-231
Overexpression of YBX1 Promotes Pancreatic Ductal Adenocarcinoma Growth via the GSK3B/Cyclin D1/Cyclin E1 Pathway.
Liu Z, Li Y, Li X, Zhao J, Wu S, Wu H, Gou S
Molecular therapy oncolytics 2020 Jun 26;17:21-30
Molecular therapy oncolytics 2020 Jun 26;17:21-30
RBFOX1 Regulates the Permeability of the Blood-Tumor Barrier via the LINC00673/MAFF Pathway.
Shen S, Yang C, Liu X, Zheng J, Liu Y, Liu L, Ma J, Ma T, An P, Lin Y, Cai H, Wang D, Li Z, Zhao L, Xue Y
Molecular therapy oncolytics 2020 Jun 26;17:138-152
Molecular therapy oncolytics 2020 Jun 26;17:138-152
MicroRNA-675-3p regulates IL-1β-stimulated human chondrocyte apoptosis and cartilage degradation by targeting GNG5.
Shen XF, Cheng Y, Dong QR, Zheng MQ
Biochemical and biophysical research communications 2020 Jun 25;527(2):458-465
Biochemical and biophysical research communications 2020 Jun 25;527(2):458-465
Circular RNA circ_0111277 attenuates human trophoblast cell invasion and migration by regulating miR-494/HTRA1/Notch-1 signal pathway in pre-eclampsia.
Ou Y, Zhu L, Wei X, Bai S, Chen M, Chen H, Zhang J
Cell death & disease 2020 Jun 25;11(6):479
Cell death & disease 2020 Jun 25;11(6):479
Targeted Delivery of Notch Inhibitor Attenuates Obesity-Induced Glucose Intolerance and Liver Fibrosis.
Richter LR, Wan Q, Wen D, Zhang Y, Yu J, Kang JK, Zhu C, McKinnon EL, Gu Z, Qiang L, Pajvani UB
ACS nano 2020 Jun 23;14(6):6878-6886
ACS nano 2020 Jun 23;14(6):6878-6886
α7nAchR mediates transcutaneous auricular vagus nerve stimulation-induced neuroprotection in a rat model of ischemic stroke by enhancing axonal plasticity.
Li J, Zhang Q, Li S, Niu L, Ma J, Wen L, Zhang L, Li C
Neuroscience letters 2020 Jun 21;730:135031
Neuroscience letters 2020 Jun 21;730:135031
Analysis of RAS protein interactions in living cells reveals a mechanism for pan-RAS depletion by membrane-targeted RAS binders.
Li YC, Lytle NK, Gammon ST, Wang L, Hayes TK, Sutton MN, Bast RC Jr, Der CJ, Piwnica-Worms D, McCormick F, Wahl GM
Proceedings of the National Academy of Sciences of the United States of America 2020 Jun 2;117(22):12121-12130
Proceedings of the National Academy of Sciences of the United States of America 2020 Jun 2;117(22):12121-12130
Immune activation of murine RAW264.7 macrophages by sonicated and alkalized paramylon from Euglena gracilis.
Guo Q, Bi D, Wu M, Yu B, Hu L, Liu C, Gu L, Zhu H, Lei A, Xu X, Wang J
BMC microbiology 2020 Jun 19;20(1):171
BMC microbiology 2020 Jun 19;20(1):171
LUZP1, a novel regulator of primary cilia and the actin cytoskeleton, is a contributing factor in Townes-Brocks Syndrome.
Bozal-Basterra L, Gonzalez-Santamarta M, Muratore V, Bermejo-Arteagabeitia A, Da Fonseca C, Barroso-Gomila O, Azkargorta M, Iloro I, Pampliega O, Andrade R, Martín-Martín N, Branon TC, Ting AY, Rodríguez JA, Carracedo A, Elortza F, Sutherland JD, Barrio R
eLife 2020 Jun 18;9
eLife 2020 Jun 18;9
Long noncoding RNA LINC00314 facilitates osteogenic differentiation of adipose-derived stem cells through the hsa-miR-129-5p/GRM5 axis via the Wnt signaling pathway.
Shi ZL, Zhang H, Fan ZY, Ma W, Song YZ, Li M, Li TQ, Cao SX, Feng GJ
Stem cell research & therapy 2020 Jun 17;11(1):240
Stem cell research & therapy 2020 Jun 17;11(1):240
Pannexin1 Channel Inhibitor (10panx) Protects Against Transient Focal Cerebral Ischemic Injury by Inhibiting RIP3 Expression and Inflammatory Response in Rats.
Wei R, Bao W, He F, Meng F, Liang H, Luo B
Neuroscience 2020 Jun 15;437:23-33
Neuroscience 2020 Jun 15;437:23-33
IL-4 Switches Microglia/macrophage M1/M2 Polarization and Alleviates Neurological Damage by Modulating the JAK1/STAT6 Pathway Following ICH.
He Y, Gao Y, Zhang Q, Zhou G, Cao F, Yao S
Neuroscience 2020 Jun 15;437:161-171
Neuroscience 2020 Jun 15;437:161-171
Perinatal low-dose PBDE-47 exposure hampered thyroglobulin turnover and induced thyroid cell apoptosis by triggering ER stress and lysosomal destabilization contributing to thyroid toxicity in adult female rats.
Li P, Gao H, Dong L, Liu L, Zhou G, Luo C, Tian Z, Xia T, Wang A, Zhang S
Journal of hazardous materials 2020 Jun 15;392:122265
Journal of hazardous materials 2020 Jun 15;392:122265
β-catenin-mediated Wnt signal transduction proceeds through an endocytosis-independent mechanism.
Rim EY, Kinney LK, Nusse R
Molecular biology of the cell 2020 Jun 15;31(13):1425-1436
Molecular biology of the cell 2020 Jun 15;31(13):1425-1436
Major depression accompanied with inflammation and multiple cytokines alterations: Evidences from clinical patients to macaca fascicularis and LPS-induced depressive mice model.
He Y, Li W, Wang Y, Tian Y, Chen X, Wu Z, Lan T, Li Y, Bai M, Liu J, Cheng K, Xie P
Journal of affective disorders 2020 Jun 15;271:262-271
Journal of affective disorders 2020 Jun 15;271:262-271
PLK1 Inhibition alleviates transplant-associated obliterative bronchiolitis by suppressing myofibroblast differentiation.
Yu J, Xu H, Cui J, Chen S, Zhang H, Zou Y, Zhao J, Le S, Jiang L, Chen Z, Liu H, Zhang D, Xia J, Wu J
Aging 2020 Jun 15;12(12):11636-11652
Aging 2020 Jun 15;12(12):11636-11652
Non-Esterified Fatty Acid-Induced Reactive Oxygen Species Mediated Granulosa Cells Apoptosis Is Regulated by Nrf2/p53 Signaling Pathway.
Wang Y, Li C, Li J, Wang G, Li L
Antioxidants (Basel, Switzerland) 2020 Jun 14;9(6)
Antioxidants (Basel, Switzerland) 2020 Jun 14;9(6)
Qian Yang Yu Yin Granule protects against hypertension-induced renal injury by epigenetic mechanism linked to Nicotinamide N-Methyltransferase (NNMT) expression.
Zhang SF, Mao XJ, Jiang WM, Fang ZY
Journal of ethnopharmacology 2020 Jun 12;255:112738
Journal of ethnopharmacology 2020 Jun 12;255:112738
Ginsenoside Rg3 promotes regression from hepatic fibrosis through reducing inflammation-mediated autophagy signaling pathway.
Liu X, Mi X, Wang Z, Zhang M, Hou J, Jiang S, Wang Y, Chen C, Li W
Cell death & disease 2020 Jun 12;11(6):454
Cell death & disease 2020 Jun 12;11(6):454
Circular RNA circZNF566 promotes hepatocellular carcinoma progression by sponging miR-4738-3p and regulating TDO2 expression.
Li S, Weng J, Song F, Li L, Xiao C, Yang W, Xu J
Cell death & disease 2020 Jun 12;11(6):452
Cell death & disease 2020 Jun 12;11(6):452
TSPO ligand Ro5-4864 modulates microglia/macrophages polarization after subarachnoid hemorrhage in mice.
Zhou J, Zhang X, Peng J, Xie Y, Du F, Guo K, Feng Y, Zhang L, Chen L, Jiang Y
Neuroscience letters 2020 Jun 11;729:134977
Neuroscience letters 2020 Jun 11;729:134977
Knockdown of fibronectin extra domain B suppresses TGF-β1-mediated cell proliferation and collagen deposition in keloid fibroblasts via AKT/ERK signaling pathway.
Cui J, Li Z, Jin C, Jin Z
Biochemical and biophysical research communications 2020 Jun 11;526(4):1131-1137
Biochemical and biophysical research communications 2020 Jun 11;526(4):1131-1137
Circular RNA (circRNA) CDYL Induces Myocardial Regeneration by ceRNA After Myocardial Infarction.
Zhang M, Wang Z, Cheng Q, Wang Z, Lv X, Wang Z, Li N
Medical science monitor : international medical journal of experimental and clinical research 2020 Jun 11;26:e923188
Medical science monitor : international medical journal of experimental and clinical research 2020 Jun 11;26:e923188
M6A-related bioinformatics analysis reveals that HNRNPC facilitates progression of OSCC via EMT.
Huang GZ, Wu QQ, Zheng ZN, Shao TR, Chen YC, Zeng WS, Lv XZ
Aging 2020 Jun 11;12(12):11667-11684
Aging 2020 Jun 11;12(12):11667-11684
Extrasynaptic CaMKIIα is involved in the antidepressant effects of ketamine by downregulating GluN2B receptors in an LPS-induced depression model.
Tang XH, Zhang GF, Xu N, Duan GF, Jia M, Liu R, Zhou ZQ, Yang JJ
Journal of neuroinflammation 2020 Jun 10;17(1):181
Journal of neuroinflammation 2020 Jun 10;17(1):181
SHQ1 is an ER stress response gene that facilitates chemotherapeutics-induced apoptosis via sensitizing ER-stress response.
Liu H, Xie S, Fang F, Kalvakolanu DV, Xiao W
Cell death & disease 2020 Jun 10;11(6):445
Cell death & disease 2020 Jun 10;11(6):445
Denatured Collagen Could Increase the Autophagy Level and Inhibit Apoptosis of Fibroblasts to Help Cell Survival and Influence Wound Healing.
Su Y, Li M, Wang X, Wang Z, Yi L
The international journal of lower extremity wounds 2020 Jun 10;:1534734620925942
The international journal of lower extremity wounds 2020 Jun 10;:1534734620925942
Downregulation of BACH1 Protects AGAINST Cerebral Ischemia/Reperfusion Injury through the Functions of HO-1 and NQO1.
Yu S, Zhai J, Yu J, Yang Q, Yang J
Neuroscience 2020 Jun 1;436:154-166
Neuroscience 2020 Jun 1;436:154-166
Phenylephrine alleviates 131I damage in submandibular gland through promoting endogenous stem cell regeneration via lissencephaly-1 upregulation.
Wang XY, Yu J, Zhang Y, Zhang FY, Liu KJ, Xiang B
Toxicology and applied pharmacology 2020 Jun 1;396:114999
Toxicology and applied pharmacology 2020 Jun 1;396:114999
DNMT1-mediated Foxp3 gene promoter hypermethylation involved in immune dysfunction caused by arsenic in human lymphocytes.
Ma Y, Ye Y, Liu Y, Chen J, Cen Y, Chen W, Yu C, Zeng Q, Zhang A, Yang G
Toxicology research 2020 Jul;9(4):519-529
Toxicology research 2020 Jul;9(4):519-529
ARHGEF10L expression regulates cell proliferation and migration in gastric tumorigenesis.
Wang DW, Tang JY, Zhang GQ, Chang XT
Bioscience, biotechnology, and biochemistry 2020 Jul;84(7):1362-1372
Bioscience, biotechnology, and biochemistry 2020 Jul;84(7):1362-1372
Costunolide improved dextran sulfate sodium-induced acute ulcerative colitis in mice through NF-κB, STAT1/3, and Akt signaling pathways.
Xie F, Zhang H, Zheng C, Shen XF
International immunopharmacology 2020 Jul;84:106567
International immunopharmacology 2020 Jul;84:106567
Acarbose, as a potential drug, effectively blocked the dynamic metastasis of EV71 from the intestine to the whole body.
Feng Q, Zhou H, Zhang X, Liu X, Wang J, Zhang C, Ma X, Quan C, Zheng Z
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases 2020 Jul;81:104210
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases 2020 Jul;81:104210
A mitophagic response to iron overload-induced oxidative damage associated with the PINK1/Parkin pathway in pancreatic beta cells.
Zhang L, Hou L, Liu Z, Huang S, Meng Z, Liang L
Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS) 2020 Jul;60:126493
Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS) 2020 Jul;60:126493
Generation of B6-Ddx4em1(CreERT2)Utr , a novel CreERT2 knock-in line, for germ cell lineage by CRISPR/Cas9.
Le HT, Hasegawa Y, Daitoku Y, Kato K, Miznuo-Iijima S, Dinh TTH, Kuba Y, Osawa Y, Mikami N, Morimoto K, Ayabe S, Tanimoto Y, Murata K, Yagami KI, Takahashi S, Mizuno S, Sugiyama F
Genesis (New York, N.Y. : 2000) 2020 Jul;58(7):e23367
Genesis (New York, N.Y. : 2000) 2020 Jul;58(7):e23367
Crocin Reverses Depression-Like Behavior in Parkinson Disease Mice via VTA-mPFC Pathway.
Tang J, Lu L, Wang Q, Liu H, Xue W, Zhou T, Xu L, Wang K, Wu D, Wei F, Tao W, Chen G
Molecular neurobiology 2020 Jul;57(7):3158-3170
Molecular neurobiology 2020 Jul;57(7):3158-3170
HSulf‑1 and palbociclib exert synergistic antitumor effects on RB‑positive triple‑negative breast cancer.
Chen F, Zhang Z, Yu Y, Liu Q, Pu F
International journal of oncology 2020 Jul;57(1):223-236
International journal of oncology 2020 Jul;57(1):223-236
Circulating Exosomes From Lipopolysaccharide-Induced Ards Mice Trigger Endoplasmic Reticulum Stress in Lung Tissue.
Tang X, Yu Q, Wen X, Qi D, Peng J, He J, Deng W, Zhu T, Zhao Y, Wang D
Shock (Augusta, Ga.) 2020 Jul;54(1):110-118
Shock (Augusta, Ga.) 2020 Jul;54(1):110-118
Matrix Metalloproteinase 11 as a Novel Tumor Promoter and Diagnostic and Prognostic Biomarker for Pancreatic Ductal Adenocarcinoma.
Zhang X, Lu J, Zhou L, You L, Liang Z, Guo J, Zhao Y
Pancreas 2020 Jul;49(6):812-821
Pancreas 2020 Jul;49(6):812-821
Methionine Enkephalin Suppresses Osteocyte Apoptosis Induced by Compressive Force through Regulation of Nuclear Translocation of NFATc1.
Sogi C, Takeshita N, Jiang W, Kim S, Maeda T, Yoshida M, Oyanagi T, Ito A, Kimura S, Seki D, Takano I, Sakai Y, Fujiwara I, Kure S, Takano-Yamamoto T
JBMR plus 2020 Jul;4(7):e10369
JBMR plus 2020 Jul;4(7):e10369
S100A14 suppresses metastasis of nasopharyngeal carcinoma by inhibition of NF-kB signaling through degradation of IRAK1.
Meng DF, Sun R, Liu GY, Peng LX, Zheng LS, Xie P, Lin ST, Mei Y, Qiang YY, Li CZ, Xu L, Peng XS, Hu H, Lang YH, Liu ZJ, Wang MD, Guo LL, Xie DH, Shu DT, Li HF, Luo FF, Niu XT, Huang BJ, Qian CN
Oncogene 2020 Jul;39(30):5307-5322
Oncogene 2020 Jul;39(30):5307-5322
Transcription factorIRX5 promotes hepatocellular carcinoma proliferation and inhibits apoptosis by regulating the p53 signalling pathway.
Zhu L, Dai L, Yang N, Liu M, Ma S, Li C, Shen J, Lin T, Wang D, Pan W, Li X
Cell biochemistry and function 2020 Jul;38(5):621-629
Cell biochemistry and function 2020 Jul;38(5):621-629
Thyrotropin receptor signaling deficiency impairs spatial learning and memory in mice.
Luan S, Bi W, Shi S, Peng L, Li Z, Jiang J, Gao L, Du Y, Hou X, He Z, Zhao J
The Journal of endocrinology 2020 Jul;246(1):41-55
The Journal of endocrinology 2020 Jul;246(1):41-55
Porcine RACK1 negatively regulates the infection of classical swine fever virus and the NF-κB activation in PK-15 cells.
Wang X, Gao L, Yang X, Zuo Q, Lan R, Li M, Yang C, Lin Y, Liu J, Yin G
Veterinary microbiology 2020 Jul;246:108711
Veterinary microbiology 2020 Jul;246:108711
UHRF1 predicts poor prognosis by triggering cell cycle in lung adenocarcinoma.
Tu Z, Deng X, Hou S, Feng A, Zhang Q
Journal of cellular and molecular medicine 2020 Jul;24(14):8069-8077
Journal of cellular and molecular medicine 2020 Jul;24(14):8069-8077
p75NTR optimizes the osteogenic potential of human periodontal ligament stem cells by up-regulating α1 integrin expression.
Li J, Zhao M, Wang Y, Shen M, Wang S, Tang M, Li M, Luo Y, Yang K, Wen X
Journal of cellular and molecular medicine 2020 Jul;24(13):7563-7575
Journal of cellular and molecular medicine 2020 Jul;24(13):7563-7575
Progress in the research of p53 tumour suppressor activity controlled by Numb in triple-negative breast cancer.
Xian J, Cheng Y, Qin X, Cao Y, Luo Y, Cao Y
Journal of cellular and molecular medicine 2020 Jul;24(13):7451-7459
Journal of cellular and molecular medicine 2020 Jul;24(13):7451-7459
Autophagy assuages myocardial infarction through Nrf2 signaling activation-mediated reactive oxygen species clear.
Sun B, Xu Y, Liu ZY, Meng WX, Yang H
European review for medical and pharmacological sciences 2020 Jul;24(13):7381-7390
European review for medical and pharmacological sciences 2020 Jul;24(13):7381-7390
Reversal of prolonged obesity-associated cerebrovascular dysfunction by inhibiting microglial Tak1.
Shen Q, Chen Z, Zhao F, Pan S, Zhang T, Cheng X, Zhang L, Zhang S, Qi J, Li J, Cai D, Zhang G
Nature neuroscience 2020 Jul;23(7):832-841
Nature neuroscience 2020 Jul;23(7):832-841
Wnt10b-overexpressing umbilical cord mesenchymal stem cells promote critical size rat calvarial defect healing by enhanced osteogenesis and VEGF-mediated angiogenesis.
Liu Y, Fang J, Zhang Q, Zhang X, Cao Y, Chen W, Shao Z, Yang S, Wu D, Hung M, Zhang Y, Tong W, Tian H
Journal of orthopaedic translation 2020 Jul;23:29-37
Journal of orthopaedic translation 2020 Jul;23:29-37
Antioxidant-related catalase CTA1 regulates development, aflatoxin biosynthesis, and virulence in pathogenic fungus Aspergillus flavus.
Zhu Z, Yang M, Bai Y, Ge F, Wang S
Environmental microbiology 2020 Jul;22(7):2792-2810
Environmental microbiology 2020 Jul;22(7):2792-2810
High expression of CDCA7 predicts tumor progression and poor prognosis in human colorectal cancer.
Li S, Huang J, Qin M, Zhang J, Liao C
Molecular medicine reports 2020 Jul;22(1):57-66
Molecular medicine reports 2020 Jul;22(1):57-66
MicroRNA‑93 promotes angiogenesis and attenuates remodeling via inactivation of the Hippo/Yap pathway by targeting Lats2 after myocardial infarctionω.
Ma C, Peng P, Zhou Y, Liu T, Wang L, Lu C
Molecular medicine reports 2020 Jul;22(1):483-493
Molecular medicine reports 2020 Jul;22(1):483-493
LncRNA MALAT1 affects the migration and invasion of trophoblast cells by regulating FOS expression in early-onset preeclampsia.
Li Q, Wang T, Huang S, Zuo Q, Jiang Z, Yang N, Sun L
Pregnancy hypertension 2020 Jul;21:50-57
Pregnancy hypertension 2020 Jul;21:50-57
Metastasis-associated gene MAPK15 promotes the migration and invasion of osteosarcoma cells via the c-Jun/MMPs pathway.
Su Z, Yang B, Zeng Z, Zhu S, Wang C, Lei S, Jiang Y, Lin L
Oncology letters 2020 Jul;20(1):99-112
Oncology letters 2020 Jul;20(1):99-112
PRR11 and SKA2 promote the proliferation, migration and invasion of esophageal carcinoma cells.
Chen J, Yang HM, Zhou HC, Peng RR, Niu ZX, Kang CY
Oncology letters 2020 Jul;20(1):639-646
Oncology letters 2020 Jul;20(1):639-646
miR-96-5p regulated TGF-β/SMAD signaling pathway and suppressed endometrial cell viability and migration via targeting TGFBR1.
Chen S, Luo Y, Cui L, Yang Q
Cell cycle (Georgetown, Tex.) 2020 Jul;19(14):1740-1753
Cell cycle (Georgetown, Tex.) 2020 Jul;19(14):1740-1753
GL-V9 reverses adriamycin resistance in hepatocellular carcinoma cells by affecting JNK2-related autophagy.
Yang Y, Liao Y, Gui YP, Zhao L, Guo LB
Chinese journal of natural medicines 2020 Jul;18(7):491-499
Chinese journal of natural medicines 2020 Jul;18(7):491-499
Artemisinin inhibits the replication of flaviviruses by promoting the type I interferon production.
Wang X, Zheng B, Ashraf U, Zhang H, Cao C, Li Q, Chen Z, Imran M, Chen H, Cao S, Ye J
Antiviral research 2020 Jul;179:104810
Antiviral research 2020 Jul;179:104810
Label-Free Quantitative Proteomic Profiling of LAD2 Mast Cell Releasates Reveals the Mechanism of Tween-80-Induced Anaphylactoid Reaction.
Mi YN, Yan PP, Di J, Cao L, Xiao X, Liu DZ, Cao YX
Proteomics. Clinical applications 2020 Jul;14(4):e1900065
Proteomics. Clinical applications 2020 Jul;14(4):e1900065
miR-429-CRKL axis regulates clear cell renal cell carcinoma malignant progression through SOS1/MEK/ERK/MMP2/MMP9 pathway.
Wang J, Wang C, Li Q, Guo C, Sun W, Zhao D, Jiang S, Hao L, Tian Y, Liu S, Sun MZ
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Jul;127:110215
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Jul;127:110215
Isocitrate dehydrogenase 2 contributes to radiation resistance of oesophageal squamous cell carcinoma via regulating mitochondrial function and ROS/pAKT signalling.
Chen X, Zhuo S, Xu W, Chen X, Huang D, Sun X, Cheng Y
British journal of cancer 2020 Jul;123(1):126-136
British journal of cancer 2020 Jul;123(1):126-136
Integration of in vitro data from three dimensionally cultured HepaRG cells and physiologically based pharmacokinetic modeling for assessment of acetaminophen hepatotoxicity.
Zhang C, Zhang Q, Li J, Yu L, Li F, Li W, Li Y, Peng H, Zhao J, Carmichael PL, Wang Y, Peng S, Guo J
Regulatory toxicology and pharmacology : RTP 2020 Jul;114:104661
Regulatory toxicology and pharmacology : RTP 2020 Jul;114:104661
High expression of KITLG is a new hallmark activating the MAPK pathway in type A and AB thymoma.
Yang Z, Liu S, Wang Y, Chen Y, Zhang P, Liu Y, Zhang H, Zhang P, Tao Z, Xiong K
Thoracic cancer 2020 Jul;11(7):1944-1954
Thoracic cancer 2020 Jul;11(7):1944-1954
RDP3, A Novel Antigout Peptide Derived from Water Extract of Rice.
Liu N, Wang Y, Zeng L, Yin S, Hu Y, Li S, Fu Y, Zhang X, Xie C, Shu L, Li Y, Sun H, Yang M, Sun J, Yang X
Journal of agricultural and food chemistry 2020 Jul 8;68(27):7143-7151
Journal of agricultural and food chemistry 2020 Jul 8;68(27):7143-7151
Matrine inhibits the growth of natural killer/T-cell lymphoma cells by modulating CaMKIIγ-c-Myc signaling pathway.
Gu J, Zhang Y, Wang X, Xiang J, Deng S, Wu D, Chen J, Yu L, Zhou Y, Wang Y, Shen J
BMC complementary medicine and therapies 2020 Jul 8;20(1):214
BMC complementary medicine and therapies 2020 Jul 8;20(1):214
Opposing biological functions of the cytoplasm and nucleus DAXX modified by SUMO-2/3 in gastric cancer.
Chen C, Sun X, Xie W, Chen S, Hu Y, Xing D, Xu J, Chen X, Zhao Z, Han Z, Xue X, Shen X, Lin K
Cell death & disease 2020 Jul 8;11(7):514
Cell death & disease 2020 Jul 8;11(7):514
κB-Ras and Ral GTPases regulate acinar to ductal metaplasia during pancreatic adenocarcinoma development and pancreatitis.
Beel S, Kolloch L, Apken LH, Jürgens L, Bolle A, Sudhof N, Ghosh S, Wardelmann E, Meisterernst M, Steinestel K, Oeckinghaus A
Nature communications 2020 Jul 8;11(1):3409
Nature communications 2020 Jul 8;11(1):3409
Cerebral Blood Flow-Guided Manipulation of Arterial Blood Pressure Attenuates Hippocampal Apoptosis After Asphyxia-Induced Cardiac Arrest in Rats.
Wang CH, Chang WT, Huang CH, Tsai MS, Liu SH, Chen WJ
Journal of the American Heart Association 2020 Jul 7;9(13):e016513
Journal of the American Heart Association 2020 Jul 7;9(13):e016513
CXCL5 promotes gastric cancer metastasis by inducing epithelial-mesenchymal transition and activating neutrophils.
Mao Z, Zhang J, Shi Y, Li W, Shi H, Ji R, Mao F, Qian H, Xu W, Zhang X
Oncogenesis 2020 Jul 6;9(7):63
Oncogenesis 2020 Jul 6;9(7):63
TRIM24 facilitates antiviral immunity through mediating K63-linked TRAF3 ubiquitination.
Zhu Q, Yu T, Gan S, Wang Y, Pei Y, Zhao Q, Pei S, Hao S, Yuan J, Xu J, Hou F, Wu X, Peng C, Wu P, Qin J, Xiao Y
The Journal of experimental medicine 2020 Jul 6;217(7)
The Journal of experimental medicine 2020 Jul 6;217(7)
Synthesis of a Hexavalent Betulinic Acid Derivative as a Hemagglutinin-Targeted Influenza Virus Entry Inhibitor.
Chen Y, Wang X, Zhu Y, Si L, Zhang B, Zhang Y, Zhang L, Zhou D, Xiao S
Molecular pharmaceutics 2020 Jul 6;17(7):2546-2554
Molecular pharmaceutics 2020 Jul 6;17(7):2546-2554
Spermidine activates RIP1 deubiquitination to inhibit TNF-α-induced NF-κB/p65 signaling pathway in osteoarthritis.
Chen Z, Lin CX, Song B, Li CC, Qiu JX, Li SX, Lin SP, Luo WQ, Fu Y, Fang GB, Wei-Ping L, Saw PE, Ding Y
Cell death & disease 2020 Jul 6;11(7):503
Cell death & disease 2020 Jul 6;11(7):503
Loss of HMGCS2 Enhances Lipogenesis and Attenuates the Protective Effect of the Ketogenic Diet in Liver Cancer.
Wang YH, Suk FM, Liao YJ
Cancers 2020 Jul 4;12(7)
Cancers 2020 Jul 4;12(7)
Apoptotic neurodegeneration in whitefly promotes the spread of TYLCV.
Wang S, Guo H, Ge F, Sun Y
eLife 2020 Jul 30;9
eLife 2020 Jul 30;9
Assessment of insulin resistance in the skeletal muscle of mice using positron emission tomography/computed tomography imaging.
Miyatake Y, Mishima Y, Tsutsumi R, Otani T, Suemasa N, Masumoto S, Kuroda M, Sakaue H
Biochemical and biophysical research communications 2020 Jul 30;528(3):499-505
Biochemical and biophysical research communications 2020 Jul 30;528(3):499-505
Application of Antibodies to Neuronally Expressed Nogo-A Increases Neuronal Survival and Neurite Outgrowth.
Nagaraj V, Theis T, Johal AS, Seth A, Gore J, Arsha N, Patel M, Hao HB, Kurian N, Schachner M
International journal of molecular sciences 2020 Jul 30;21(15)
International journal of molecular sciences 2020 Jul 30;21(15)
EN2 as an oncogene promotes tumor progression via regulating CCL20 in colorectal cancer.
Li Y, Liu J, Xiao Q, Tian R, Zhou Z, Gan Y, Li Y, Shu G, Yin G
Cell death & disease 2020 Jul 30;11(7):604
Cell death & disease 2020 Jul 30;11(7):604
MCF7 Spheroid Development: New Insight about Spatio/Temporal Arrangements of TNTs, Amyloid Fibrils, Cell Connections, and Cellular Bridges.
Pulze L, Congiu T, Brevini TAL, Grimaldi A, Tettamanti G, D'Antona P, Baranzini N, Acquati F, Ferraro F, de Eguileor M
International journal of molecular sciences 2020 Jul 29;21(15)
International journal of molecular sciences 2020 Jul 29;21(15)
LncRNA PVT1 promotes gemcitabine resistance of pancreatic cancer via activating Wnt/β-catenin and autophagy pathway through modulating the miR-619-5p/Pygo2 and miR-619-5p/ATG14 axes.
Zhou C, Yi C, Yi Y, Qin W, Yan Y, Dong X, Zhang X, Huang Y, Zhang R, Wei J, Ali DW, Michalak M, Chen XZ, Tang J
Molecular cancer 2020 Jul 29;19(1):118
Molecular cancer 2020 Jul 29;19(1):118
Sensitive Signal Amplifying a Diagnostic Biochip Based on a Biomimetic Periodic Nanostructure for Detecting Cancer Exosomes.
Zhang J, Zhu Y, Shi J, Zhang K, Zhang Z, Zhang H
ACS applied materials & interfaces 2020 Jul 29;12(30):33473-33482
ACS applied materials & interfaces 2020 Jul 29;12(30):33473-33482
CircATRNL1 promotes epithelial-mesenchymal transition in endometriosis by upregulating Yes-associated protein 1 in vitro.
Wang D, Luo Y, Wang G, Yang Q
Cell death & disease 2020 Jul 29;11(7):594
Cell death & disease 2020 Jul 29;11(7):594
The Impact of ALS-Associated Genes hnRNPA1, MATR3, VCP and UBQLN2 on the Severity of TDP-43 Aggregation.
Bajc Česnik A, Motaln H, Rogelj B
Cells 2020 Jul 28;9(8)
Cells 2020 Jul 28;9(8)
mTORC1-dependent TFEB nucleus translocation and pro-survival autophagy induced by zeolitic imidazolate framework-8.
Ding H, Song Y, Huang X, Wang L, Luo S, Zhang H, Pan H, Jiang W, Qian J, Yao G, Wen L, Zhang Y
Biomaterials science 2020 Jul 28;8(15):4358-4369
Biomaterials science 2020 Jul 28;8(15):4358-4369
Suppression of PTTG1 inhibits cell angiogenesis, migration and invasion in glioma cells.
Cui L, Ren T, Zhao H, Chen S, Zheng M, Gao X, Feng D, Yang L, Jin X, Zhuo R
Medical oncology (Northwood, London, England) 2020 Jul 28;37(8):73
Medical oncology (Northwood, London, England) 2020 Jul 28;37(8):73
Correlation between the HIF-1α/Notch signaling pathway and Modic changes in nucleus pulposus cells isolated from patients with low back pain.
Xiong Z, Ding J, Zhou J, Yao S, Zheng J, Guo X
BMC musculoskeletal disorders 2020 Jul 28;21(1):500
BMC musculoskeletal disorders 2020 Jul 28;21(1):500
Gold Nanoparticles Induce Tumor Vessel Normalization and Impair Metastasis by Inhibiting Endothelial Smad2/3 Signaling.
Huang N, Liu Y, Fang Y, Zheng S, Wu J, Wang M, Zhong W, Shi M, Xing M, Liao W
ACS nano 2020 Jul 28;14(7):7940-7958
ACS nano 2020 Jul 28;14(7):7940-7958
Structural and Biological Basis of Alphacoronavirus nsp1 Associated with Host Proliferation and Immune Evasion.
Shen Z, Yang Y, Yang S, Zhang G, Xiao S, Fu ZF, Peng G
Viruses 2020 Jul 28;12(8)
Viruses 2020 Jul 28;12(8)
The cross-talk between DDR1 and STAT3 promotes the development of hepatocellular carcinoma.
Lin Y, Jin H, Wu X, Jian Z, Zou X, Huang J, Guan R, Wei X
Aging 2020 Jul 27;12(14):14391-14405
Aging 2020 Jul 27;12(14):14391-14405
Histone deacetylase 4 inhibits NF-κB activation by facilitating IκBα sumoylation.
Yang Q, Tang J, Xu C, Zhao H, Zhou Y, Wang Y, Yang M, Chen X, Chen J
Journal of molecular cell biology 2020 Jul 27;12(12):933-945
Journal of molecular cell biology 2020 Jul 27;12(12):933-945
FLIM-FRET-Based Structural Characterization of a Class-A GPCR Dimer in the Cell Membrane.
Yang J, Gong Z, Lu YB, Xu CJ, Wei TF, Yang MS, Zhan TW, Yang YH, Lin L, Liu J, Tang C, Zhang WP
Journal of molecular biology 2020 Jul 24;432(16):4596-4611
Journal of molecular biology 2020 Jul 24;432(16):4596-4611
Glucosylation by the Legionella Effector SetA Promotes the Nuclear Localization of the Transcription Factor TFEB.
Beck WHJ, Kim D, Das J, Yu H, Smolka MB, Mao Y
iScience 2020 Jul 24;23(7):101300
iScience 2020 Jul 24;23(7):101300
LINC00266-1/miR-548c-3p/SMAD2 feedback loop stimulates the development of osteosarcoma.
Zheng S, Wan L, Ge D, Jiang F, Qian Z, Tang J, Yang J, Yao Y, Yan J, Zhao L, Li H, Yang L
Cell death & disease 2020 Jul 24;11(7):576
Cell death & disease 2020 Jul 24;11(7):576
Ddx56 maintains proliferation of mouse embryonic stem cells via ribosome assembly and interaction with the Oct4/Sox2 complex.
Wang J, Liu J, Ye M, Liu F, Wu S, Huang J, Shi G
Stem cell research & therapy 2020 Jul 23;11(1):314
Stem cell research & therapy 2020 Jul 23;11(1):314
The food contaminant deoxynivalenol provokes metabolic impairments resulting in non-alcoholic fatty liver (NAFL) in mice.
Barbouche R, Gaigé S, Airault C, Poirot K, Dallaporta M, Troadec JD, Abysique A
Scientific reports 2020 Jul 21;10(1):12072
Scientific reports 2020 Jul 21;10(1):12072
Reduced intracellular chloride concentration impairs angiogenesis by inhibiting oxidative stress-mediated VEGFR2 activation.
Li K, Liu YY, Lv XF, Lin ZM, Zhang TT, Zhang FR, Guo JW, Hong Y, Liu X, Lin XC, Zhou JG, Wu QQ, Liang SJ, Shang JY
Acta pharmacologica Sinica 2020 Jul 21;
Acta pharmacologica Sinica 2020 Jul 21;
CTCF promotes colorectal cancer cell proliferation and chemotherapy resistance to 5-FU via the P53-Hedgehog axis.
Lai Q, Li Q, He C, Fang Y, Lin S, Cai J, Ding J, Zhong Q, Zhang Y, Wu C, Wang X, He J, Liu Y, Yan Q, Li A, Liu S
Aging 2020 Jul 20;12(16):16270-16293
Aging 2020 Jul 20;12(16):16270-16293
Leukemogenic Chromatin Alterations Promote AML Leukemia Stem Cells via a KDM4C-ALKBH5-AXL Signaling Axis.
Wang J, Li Y, Wang P, Han G, Zhang T, Chang J, Yin R, Shan Y, Wen J, Xie X, Feng M, Wang Q, Hu J, Cheng Y, Zhang T, Li Y, Gao Z, Guo C, Wang J, Liang J, Cui M, Gao K, Chai J, Liu W, Cheng H, Li L, Zhou F, Liu L, Luo Y, Li S, Zhang H
Cell stem cell 2020 Jul 2;27(1):81-97.e8
Cell stem cell 2020 Jul 2;27(1):81-97.e8
SIRT1 alleviates high-magnitude compression-induced senescence in nucleus pulposus cells via PINK1-dependent mitophagy.
Wang Y, Wang H, Zhuo Y, Hu Y, Zhang Z, Ye J, Liu L, Luo L, Zhao C, Zhou Q, Li P
Aging 2020 Jul 18;12(16):16126-16141
Aging 2020 Jul 18;12(16):16126-16141
The urea transporter UT-A1 plays a predominant role in a urea-dependent urine-concentrating mechanism.
Geng X, Zhang S, He J, Ma A, Li Y, Li M, Zhou H, Chen G, Yang B
The Journal of biological chemistry 2020 Jul 17;295(29):9893-9900
The Journal of biological chemistry 2020 Jul 17;295(29):9893-9900
A Nimbolide-Based Kinase Degrader Preferentially Degrades Oncogenic BCR-ABL.
Tong B, Spradlin JN, Novaes LFT, Zhang E, Hu X, Moeller M, Brittain SM, McGregor LM, McKenna JM, Tallarico JA, Schirle M, Maimone TJ, Nomura DK
ACS chemical biology 2020 Jul 17;15(7):1788-1794
ACS chemical biology 2020 Jul 17;15(7):1788-1794
RNF126-Mediated Reubiquitination Is Required for Proteasomal Degradation of p97-Extracted Membrane Proteins.
Hu X, Wang L, Wang Y, Ji J, Li J, Wang Z, Li C, Zhang Y, Zhang ZR
Molecular cell 2020 Jul 16;79(2):320-331.e9
Molecular cell 2020 Jul 16;79(2):320-331.e9
Intracellular expression of arginine deiminase activates the mitochondrial apoptosis pathway by inhibiting cytosolic ferritin and inducing chromatin autophagy.
Feng Q, Bian X, Liu X, Wang Y, Zhou H, Ma X, Quan C, Yao Y, Zheng Z
BMC cancer 2020 Jul 16;20(1):665
BMC cancer 2020 Jul 16;20(1):665
BMMSC-sEV-derived miR-328a-3p promotes ECM remodeling of damaged urethral sphincters via the Sirt7/TGFβ signaling pathway.
Zhang H, Huang J, Liu J, Li Y, Gao Y
Stem cell research & therapy 2020 Jul 16;11(1):286
Stem cell research & therapy 2020 Jul 16;11(1):286
Nedd8-activating enzyme inhibitor MLN4924 (Pevonedistat), inhibits miR-1303 to suppress human breast cancer cell proliferation via targeting p27Kip1.
Chen Y, Du M, Yusuying S, Liu W, Tan Y, Xie P
Experimental cell research 2020 Jul 15;392(2):112038
Experimental cell research 2020 Jul 15;392(2):112038
Effective-component compatibility of Bufei Yishen formula II inhibits mucus hypersecretion of chronic obstructive pulmonary disease rats by regulating EGFR/PI3K/mTOR signaling.
Li J, Ma J, Tian Y, Zhao P, Liu X, Dong H, Zheng W, Feng S, Zhang L, Wu M, Zhu L, Liu S, Zhao D
Journal of ethnopharmacology 2020 Jul 15;257:112796
Journal of ethnopharmacology 2020 Jul 15;257:112796
ZIC2 is downregulated and represses tumor growth via the regulation of STAT3 in breast cancer.
Liu ZH, Chen ML, Zhang Q, Zhang Y, An X, Luo YL, Liu XM, Liu SX, Liu Q, Yang T, Liu YM, Liu BL, Zhou AJ, Li MZ, Liu YJ, Liu ZX, Zhong Q
International journal of cancer 2020 Jul 15;147(2):505-518
International journal of cancer 2020 Jul 15;147(2):505-518
Excessive Polyamine Generation in Keratinocytes Promotes Self-RNA Sensing by Dendritic Cells in Psoriasis.
Lou F, Sun Y, Xu Z, Niu L, Wang Z, Deng S, Liu Z, Zhou H, Bai J, Yin Q, Cai X, Sun L, Wang H, Li Q, Wu Z, Chen X, Gu J, Shi YL, Tao W, Ginhoux F, Wang H
Immunity 2020 Jul 14;53(1):204-216.e10
Immunity 2020 Jul 14;53(1):204-216.e10
Circular RNA CDR1as Exerts Oncogenic Properties Partially through Regulating MicroRNA 641 in Cholangiocarcinoma.
Li D, Tang Z, Gao Z, Shen P, Liu Z, Dang X
Molecular and cellular biology 2020 Jul 14;40(15)
Molecular and cellular biology 2020 Jul 14;40(15)
CPEB3 inhibits epithelial-mesenchymal transition by disrupting the crosstalk between colorectal cancer cells and tumor-associated macrophages via IL-6R/STAT3 signaling.
Zhong Q, Fang Y, Lai Q, Wang S, He C, Li A, Liu S, Yan Q
Journal of experimental & clinical cancer research : CR 2020 Jul 11;39(1):132
Journal of experimental & clinical cancer research : CR 2020 Jul 11;39(1):132
Synaptopodin-2 promotes hepatocellular carcinoma metastasis via calcineurin-induced nuclear-cytoplasmic translocation.
Gao J, Zhang HP, Sun YH, Guo WZ, Li J, Tang HW, Guo DF, Zhang JK, Shi XY, Yu DS, Zhang XD, Wen PH, Shi JH, Zhang SJ
Cancer letters 2020 Jul 10;482:8-18
Cancer letters 2020 Jul 10;482:8-18
ETV4 is a theranostic target in clear cell renal cell carcinoma that promotes metastasis by activating the pro-metastatic gene FOSL1 in a PI3K-AKT dependent manner.
Xu L, Hu H, Zheng LS, Wang MY, Mei Y, Peng LX, Qiang YY, Li CZ, Meng DF, Wang MD, Liu ZJ, Li XJ, Huang BJ, Qian CN
Cancer letters 2020 Jul 10;482:74-89
Cancer letters 2020 Jul 10;482:74-89
MiR-920 promotes osteogenic differentiation of human bone mesenchymal stem cells by targeting HOXA7.
Zha JP, Wang XQ, Di J
Journal of orthopaedic surgery and research 2020 Jul 10;15(1):254
Journal of orthopaedic surgery and research 2020 Jul 10;15(1):254
TCF7L2 rs290487 C allele aberrantly enhances hepatic gluconeogenesis through allele-specific changes in transcription and chromatin binding.
Zhang X, Ye P, Huang H, Wang B, Dong F, Ling Q
Aging 2020 Jul 10;12(13):13365-13387
Aging 2020 Jul 10;12(13):13365-13387
GABRG2 Deletion Linked to Genetic Epilepsy with Febrile Seizures Plus Affects the Expression of GABAA Receptor Subunits and Other Genes at Different Temperatures.
Li X, Guo S, Liu K, Zhang C, Chang H, Yang W, Rong S, Hu Q, Cui J, Wang F, Sun T
Neuroscience 2020 Jul 1;438:116-136
Neuroscience 2020 Jul 1;438:116-136
miR-744-5p mediates lncRNA HOTTIP to regulate the proliferation and apoptosis of papillary thyroid carcinoma cells.
Yuan Q, Fan Y, Liu Z, Wang X, Jia M, Geng Z, Zheng J, Lu X
Experimental cell research 2020 Jul 1;392(1):112024
Experimental cell research 2020 Jul 1;392(1):112024
Erythropoietin-producing hepatocellular receptor A7 restrains estrogen negative feedback of luteinizing hormone via ephrin A5 in the hypothalamus of female rats.
Li S, Zhai J, Xu B, Liu J, Chu W, Wang D, Geng X, Chen ZJ, Du Y
American journal of physiology. Endocrinology and metabolism 2020 Jul 1;319(1):E81-E90
American journal of physiology. Endocrinology and metabolism 2020 Jul 1;319(1):E81-E90
Circulating extracellular vesicles from patients with valvular heart disease induce neutrophil chemotaxis via FOXO3a and the inhibiting role of dexmedetomidine.
Yuan HX, Chen CY, Li YQ, Ning DS, Li Y, Chen YT, Li SX, Fu MX, Li XD, Ma J, Jian YP, Liu DH, Mo ZW, Peng YM, Xu KQ, Ou ZJ, Ou JS
American journal of physiology. Endocrinology and metabolism 2020 Jul 1;319(1):E217-E231
American journal of physiology. Endocrinology and metabolism 2020 Jul 1;319(1):E217-E231
A role of the frontotemporal lobar degeneration risk factor TMEM106B in myelination.
Feng T, Sheng RR, Solé-Domènech S, Ullah M, Zhou X, Mendoza CS, Enriquez LCM, Katz II, Paushter DH, Sullivan PM, Wu X, Maxfield FR, Hu F
Brain : a journal of neurology 2020 Jul 1;143(7):2255-2271
Brain : a journal of neurology 2020 Jul 1;143(7):2255-2271
Changes in Nup62 content affect contact-induced differentiation of cultured myoblasts.
Bishop PJ, Kinoshita Y, Lopes NN, Ward AS, Kohtz DS
Differentiation; research in biological diversity 2020 Jul - Aug;114:27-35
Differentiation; research in biological diversity 2020 Jul - Aug;114:27-35
LncRNA MBNL1-AS1 represses cell proliferation and enhances cell apoptosis via targeting miR-135a-5p/PHLPP2/FOXO1 axis in bladder cancer.
Wei X, Yang X, Wang B, Yang Y, Fang Z, Yi C, Shi L, Song D
Cancer medicine 2020 Jan;9(2):724-736
Cancer medicine 2020 Jan;9(2):724-736
Microglial activation contributes to depressive-like behavior in dopamine D3 receptor knockout mice.
Wang J, Lai S, Li G, Zhou T, Wang B, Cao F, Chen T, Zhang X, Chen Y
Brain, behavior, and immunity 2020 Jan;83:226-238
Brain, behavior, and immunity 2020 Jan;83:226-238
CHK2-FOXK axis promotes transcriptional control of autophagy programs.
Chen Y, Wu J, Liang G, Geng G, Zhao F, Yin P, Nowsheen S, Wu C, Li Y, Li L, Kim W, Zhou Q, Huang J, Liu J, Zhang C, Guo G, Deng M, Tu X, Gao X, Liu Z, Chen Y, Lou Z, Luo K, Yuan J
Science advances 2020 Jan;6(1):eaax5819
Science advances 2020 Jan;6(1):eaax5819
MiR-let-7d-3p regulates IL-17 expression through targeting AKT1/mTOR signaling in CD4+ T cells.
Wang J, Wang X, Wang L, Sun C, Xie C, Li Z
In vitro cellular & developmental biology. Animal 2020 Jan;56(1):67-74
In vitro cellular & developmental biology. Animal 2020 Jan;56(1):67-74
PRRX1-induced epithelial-to-mesenchymal transition in salivary adenoid cystic carcinoma activates the metabolic reprogramming of free fatty acids to promote invasion and metastasis.
Jiang YP, Tang YL, Wang SS, Wu JS, Zhang M, Pang X, Wu JB, Chen Y, Tang YJ, Liang XH
Cell proliferation 2020 Jan;53(1):e12705
Cell proliferation 2020 Jan;53(1):e12705
SIRT3 promotes the invasion and metastasis of cervical cancer cells by regulating fatty acid synthase.
Xu LX, Hao LJ, Ma JQ, Liu JK, Hasim A
Molecular and cellular biochemistry 2020 Jan;464(1-2):11-20
Molecular and cellular biochemistry 2020 Jan;464(1-2):11-20
The aqueous extract of Gentianella acuta improves isoproterenol‑induced myocardial fibrosis via inhibition of the TGF‑β1/Smads signaling pathway.
Yang HX, Xu GR, Zhang C, Sun JH, Zhang Y, Song JN, Li YF, Liu Y, Li AY
International journal of molecular medicine 2020 Jan;45(1):223-233
International journal of molecular medicine 2020 Jan;45(1):223-233
RNA-binding motif protein 10 induces apoptosis and suppresses proliferation by activating p53.
Jung JH, Lee H, Cao B, Liao P, Zeng SX, Lu H
Oncogene 2020 Jan;39(5):1031-1040
Oncogene 2020 Jan;39(5):1031-1040
Dichloroacetate restores colorectal cancer chemosensitivity through the p53/miR-149-3p/PDK2-mediated glucose metabolic pathway.
Liang Y, Hou L, Li L, Li L, Zhu L, Wang Y, Huang X, Hou Y, Zhu D, Zou H, Gu Y, Weng X, Wang Y, Li Y, Wu T, Yao M, Gross I, Gaiddon C, Luo M, Wang J, Meng X
Oncogene 2020 Jan;39(2):469-485
Oncogene 2020 Jan;39(2):469-485
Autophagy and Ubiquitin-Proteasome System Coordinate to Regulate the Protein Quality Control of Neurodegenerative Disease-Associated DCTN1.
Wang N, Ma Q, Peng P, Yu Y, Xu S, Wang G, Ying Z, Wang H
Neurotoxicity research 2020 Jan;37(1):48-57
Neurotoxicity research 2020 Jan;37(1):48-57
Fabrication of porous bovine pericardium scaffolds incorporated with bFGF for tissue engineering applications.
Liu X, Wu H, Lu F, Li Q, Xu Z
Xenotransplantation 2020 Jan;27(1):e12568
Xenotransplantation 2020 Jan;27(1):e12568
MiR-146a down-regulates inflammatory response by targeting TLR3 and TRAF6 in Coxsackievirus B infection.
Fei Y, Chaulagain A, Wang T, Chen Y, Liu J, Yi M, Wang Y, Huang Y, Lin L, Chen S, Xu W, Tong L, Wu X, Zhao D, Zhang F, Zhao W, Zhong Z
RNA (New York, N.Y.) 2020 Jan;26(1):91-100
RNA (New York, N.Y.) 2020 Jan;26(1):91-100
In utero hypoxia altered Ang II-induced contraction via PKCβ in fetal cerebral arteries.
Su H, Chen X, Zhang Y, Qi L, He Y, Lv J, Zhang Y, Li X, Tang J, Xu Z
The Journal of endocrinology 2020 Jan;244(1):213-222
The Journal of endocrinology 2020 Jan;244(1):213-222
Hic-5 deficiency protects cerulein-induced chronic pancreatitis via down-regulation of the NF-κB (p65)/IL-6 signalling pathway.
Chen H, Tan P, Qian B, Du Y, Wang A, Shi H, Huang Z, Huang S, Liang T, Fu W
Journal of cellular and molecular medicine 2020 Jan;24(2):1488-1503
Journal of cellular and molecular medicine 2020 Jan;24(2):1488-1503
MicroRNA-29b-3p suppresses oral squamous cell carcinoma cell migration and invasion via IL32/AKT signalling pathway.
He J, Ye W, Kou N, Chen K, Cui B, Zhang X, Hu S, Liu T, Kang L, Li X
Journal of cellular and molecular medicine 2020 Jan;24(1):841-849
Journal of cellular and molecular medicine 2020 Jan;24(1):841-849
Protective mechanism of SIRT1 on Hcy-induced atrial fibrosis mediated by TRPC3.
Han L, Tang Y, Li S, Wu Y, Chen X, Wu Q, Hong K, Li J
Journal of cellular and molecular medicine 2020 Jan;24(1):488-510
Journal of cellular and molecular medicine 2020 Jan;24(1):488-510
Long noncoding RNA MAGI1-IT1 regulates cardiac hypertrophy by modulating miR-302e/DKK1/Wnt/beta-catenin signaling pathway.
Zhang Q, Wang F, Wang F, Wu N
Journal of cellular physiology 2020 Jan;235(1):245-253
Journal of cellular physiology 2020 Jan;235(1):245-253
Targeting the WEE1 kinase strengthens the antitumor activity of imatinib via promoting KIT autophagic degradation in gastrointestinal stromal tumors.
Liu W, Zeng X, Yin Y, Li C, Yang W, Wan W, Shi L, Wang G, Tao K, Zhang P
Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association 2020 Jan;23(1):39-51
Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association 2020 Jan;23(1):39-51
Exome sequencing revealed Notch ligand JAG1 as a novel candidate gene for familial exudative vitreoretinopathy.
Zhang L, Zhang X, Xu H, Huang L, Zhang S, Liu W, Yang Y, Fei P, Li S, Yang M, Zhao P, Zhu X, Yang Z
Genetics in medicine : official journal of the American College of Medical Genetics 2020 Jan;22(1):77-84
Genetics in medicine : official journal of the American College of Medical Genetics 2020 Jan;22(1):77-84
Activity and mechanism of flavokawain A in inhibiting P-glycoprotein expression in paclitaxel resistance of lung cancer.
Li J, Zheng L, Yan M, Wu J, Liu Y, Tian X, Jiang W, Zhang L, Wang R
Oncology letters 2020 Jan;19(1):379-387
Oncology letters 2020 Jan;19(1):379-387
Receptor tyrosine kinase inhibitors block proliferation of TGEV mainly through p38 mitogen-activated protein kinase pathways.
Dong W, Xie W, Liu Y, Sui B, Zhang H, Liu L, Tan Y, Tong X, Fu ZF, Yin P, Fang L, Peng G
Antiviral research 2020 Jan;173:104651
Antiviral research 2020 Jan;173:104651
Functional heritage: the evolution of chimeric RNA into a gene.
Wu H, Singh S, Shi X, Xie Z, Lin E, Li X, Li H
RNA biology 2020 Jan;17(1):125-134
RNA biology 2020 Jan;17(1):125-134
Activation of PPARA-mediated autophagy reduces Alzheimer disease-like pathology and cognitive decline in a murine model.
Luo R, Su LY, Li G, Yang J, Liu Q, Yang LX, Zhang DF, Zhou H, Xu M, Fan Y, Li J, Yao YG
Autophagy 2020 Jan;16(1):52-69
Autophagy 2020 Jan;16(1):52-69
FGF9 knockout in GABAergic neurons induces apoptosis and inflammation via the Fas/caspase-3 pathway in the cerebellum of mice.
Guo M, Chen H, Duan W, Li Z, Li Y, Ma Y, Xu X, Yi L, Bi Y, Liu Y, Zhang J, Li C
Brain research bulletin 2020 Jan;154:91-101
Brain research bulletin 2020 Jan;154:91-101
Alpha-hemolysin of uropathogenic Escherichia coli induces GM-CSF-mediated acute kidney injury.
Wang C, Li Q, Lv J, Sun X, Cao Y, Yu K, Miao C, Zhang ZS, Yao Z, Wang Q
Mucosal immunology 2020 Jan;13(1):22-33
Mucosal immunology 2020 Jan;13(1):22-33
Osthole inhibits cell proliferation by regulating the TGF-β1/Smad/p38 signaling pathways in pulmonary arterial smooth muscle cells.
Yue Y, Li YQ, Fu S, Wu YT, Zhu L, Hua L, Lv JY, Li YL, Yang DL
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Jan;121:109640
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Jan;121:109640
Long noncoding RNA CASC21 exerts an oncogenic role in colorectal cancer through regulating miR-7-5p/YAP1 axis.
Zheng Y, Nie P, Xu S
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Jan;121:109628
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Jan;121:109628
Convallatoxin induces HaCaT cell necroptosis and ameliorates skin lesions in psoriasis-like mouse models.
Jiang BW, Zhang WJ, Wang Y, Tan LP, Bao YL, Song ZB, Yu CL, Wang SY, Liu L, Li YX
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Jan;121:109615
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Jan;121:109615
Involvement of the p38 MAPK-pHsp27 pathway in vascular hyporeactivity induced by obstructive jaundice in rats.
Di HT, Wu XZ, Wang HQ, Chen M, Kong EL, Yu WF, Wu FX
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Jan;121:109304
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Jan;121:109304
Resveratrol induces depletion of TRAF6 and suppresses prostate cancer cell proliferation and migration.
Khusbu FY, Zhou X, Roy M, Chen FZ, Cao Q, Chen HC
The international journal of biochemistry & cell biology 2020 Jan;118:105644
The international journal of biochemistry & cell biology 2020 Jan;118:105644
Anti-inflammation effects of injectable platelet-rich fibrin via macrophages and dendritic cells.
Zhang J, Yin C, Zhao Q, Zhao Z, Wang J, Miron RJ, Zhang Y
Journal of biomedical materials research. Part A 2020 Jan;108(1):61-68
Journal of biomedical materials research. Part A 2020 Jan;108(1):61-68
Overexpression of human wtTDP-43 causes impairment in hippocampal plasticity and behavioral deficits in CAMKII-tTa transgenic mouse model.
Quadri Z, Johnson N, Zamudio F, Miller A, Peters M, Smeltzer S, Hunt JB Jr, Housley SB, Brown B, Kraner S, Norris CM, Nash K, Weeber E, Lee DC, Selenica MB
Molecular and cellular neurosciences 2020 Jan;102:103418
Molecular and cellular neurosciences 2020 Jan;102:103418
Tamoxifen induces fatty liver disease in breast cancer through the MAPK8/FoxO pathway.
Gong L, Tang H, Luo Z, Sun X, Tan X, Xie L, Lei Y, Cai M, He C, Ma J, Han S
Clinical and translational medicine 2020 Jan;10(1):137-150
Clinical and translational medicine 2020 Jan;10(1):137-150
SLC6A8 Knockdown Suppresses the Invasion and Migration of Human Hepatocellular Carcinoma Huh-7 and Hep3B Cells.
Yuan L, Wu XJ, Li WC, Zhuo C, Xu Z, Tan C, Ma R, Wang J, Pu J
Technology in cancer research & treatment 2020 Jan-Dec;19:1533033820983029
Technology in cancer research & treatment 2020 Jan-Dec;19:1533033820983029
Desloratadine, a Novel Antigrowth Reagent for Bladder Cancer.
Ma J, Qi J, Li S, Zhang C, Wang H, Shao L, Yuan X, Sha Q
Technology in cancer research & treatment 2020 Jan-Dec;19:1533033820926591
Technology in cancer research & treatment 2020 Jan-Dec;19:1533033820926591
c-Abl-p38α signaling pathway mediates dopamine neuron loss in trigeminal neuralgia.
Fu J, Mu G, Qiu L, Zhao J, Ou C
Molecular pain 2020 Jan-Dec;16:1744806920930855
Molecular pain 2020 Jan-Dec;16:1744806920930855
Satellite glial cells in sensory ganglia express functional transient receptor potential ankyrin 1 that is sensitized in neuropathic and inflammatory pain.
Shin SM, Itson-Zoske B, Cai Y, Qiu C, Pan B, Stucky CL, Hogan QH, Yu H
Molecular pain 2020 Jan-Dec;16:1744806920925425
Molecular pain 2020 Jan-Dec;16:1744806920925425
Chemokine receptor CXCR4 activates the RhoA/ROCK2 pathway in spinal neurons that induces bone cancer pain.
Xu H, Peng C, Chen XT, Yao YY, Chen LP, Yin Q, Shen W
Molecular pain 2020 Jan-Dec;16:1744806920919568
Molecular pain 2020 Jan-Dec;16:1744806920919568
Scorpion alleviates bone cancer pain through inhibition of bone destruction and glia activation.
Yu J, Luo Y, Jin H, Lv J, Zhou T, Yabasin IB, Wen Q
Molecular pain 2020 Jan-Dec;16:1744806920909993
Molecular pain 2020 Jan-Dec;16:1744806920909993
STAT3 Activation-Induced Fatty Acid Oxidation in CD8+ T Effector Cells Is Critical for Obesity-Promoted Breast Tumor Growth.
Zhang C, Yue C, Herrmann A, Song J, Egelston C, Wang T, Zhang Z, Li W, Lee H, Aftabizadeh M, Li YJ, Lee PP, Forman S, Somlo G, Chu P, Kruper L, Mortimer J, Hoon DSB, Huang W, Priceman S, Yu H
Cell metabolism 2020 Jan 7;31(1):148-161.e5
Cell metabolism 2020 Jan 7;31(1):148-161.e5
CD2AP links actin to PI3 kinase activity to extend epithelial cell height and constrain cell area.
Wang Y, Brieher WM
The Journal of cell biology 2020 Jan 6;219(1)
The Journal of cell biology 2020 Jan 6;219(1)
A novel IFNα-induced long noncoding RNA negatively regulates immunosuppression by interrupting H3K27 acetylation in head and neck squamous cell carcinoma.
Ma H, Chang H, Yang W, Lu Y, Hu J, Jin S
Molecular cancer 2020 Jan 6;19(1):4
Molecular cancer 2020 Jan 6;19(1):4
An Alu Element Insertion in Intron 1 Results in Aberrant Alternative Splicing of APOBEC3G Pre-mRNA in Northern Pig-Tailed Macaques (Macaca leonina) That May Reduce APOBEC3G-Mediated Hypermutation Pressure on HIV-1.
Zhang XL, Luo MT, Song JH, Pang W, Zheng YT
Journal of virology 2020 Jan 31;94(4)
Journal of virology 2020 Jan 31;94(4)
Isoliquiritigenin inhibits the proliferation, migration and metastasis of Hep3B cells via suppressing cyclin D1 and PI3K/AKT pathway.
Huang Y, Liu C, Zeng WC, Xu GY, Wu JM, Li ZW, Huang XY, Lin RJ, Shi X
Bioscience reports 2020 Jan 31;40(1)
Bioscience reports 2020 Jan 31;40(1)
17β-estradiol binding to ERα promotes the progression of prolactinoma through estrogen-response element-induced CaBP-9k up-regulation.
Liu J, Han H, Lu W, Fan G
Bioscience reports 2020 Jan 31;40(1)
Bioscience reports 2020 Jan 31;40(1)
ADAM12 is A Potential Therapeutic Target Regulated by Hypomethylation in Triple-Negative Breast Cancer.
Mendaza S, Ulazia-Garmendia A, Monreal-Santesteban I, Córdoba A, Azúa YR, Aguiar B, Beloqui R, Armendáriz P, Arriola M, Martín-Sánchez E, Guerrero-Setas D
International journal of molecular sciences 2020 Jan 30;21(3)
International journal of molecular sciences 2020 Jan 30;21(3)
The synthetic cannabinoid dehydroxylcannabidiol restores the function of a major GABAA receptor isoform in a cell model of hyperekplexia.
Zou G, Xia J, Han Q, Liu D, Xiong W
The Journal of biological chemistry 2020 Jan 3;295(1):138-145
The Journal of biological chemistry 2020 Jan 3;295(1):138-145
Inhibition of long non-coding RNA metastasis-associated lung adenocarcinoma transcript 1 attenuates high glucose-induced cardiomyocyte apoptosis via regulation of miR-181a-5p.
Cheng Y, Li J, Wang C, Yang H, Wang Y, Zhan T, Guo S, Liang J, Bai Y, Yu J, Liu G
Experimental animals 2020 Jan 29;69(1):34-44
Experimental animals 2020 Jan 29;69(1):34-44
Hedgehog signaling promotes sorafenib resistance in hepatocellular carcinoma patient-derived organoids.
Wang S, Wang Y, Xun X, Zhang C, Xiang X, Cheng Q, Hu S, Li Z, Zhu J
Journal of experimental & clinical cancer research : CR 2020 Jan 28;39(1):22
Journal of experimental & clinical cancer research : CR 2020 Jan 28;39(1):22
Mechanical force regulation of YAP by F-actin and GPCR revealed by super-resolution imaging.
Gao J, He L, Zhou L, Jing Y, Wang F, Shi Y, Cai M, Sun J, Xu H, Jiang J, Zhang L, Wang H
Nanoscale 2020 Jan 28;12(4):2703-2714
Nanoscale 2020 Jan 28;12(4):2703-2714
Scutellarin inhibition of the rosuvastatin uptake in rat hepatocytes and the competition for organic anion transporting polypeptide 1B1 in HEK293T cells.
Liu J, Guo Y, Liu K, Ye X, Wang F, Xu Y, Xia C
Scientific reports 2020 Jan 28;10(1):1308
Scientific reports 2020 Jan 28;10(1):1308
Proteomic and lipidomic analysis of exosomes derived from ovarian cancer cells and ovarian surface epithelial cells.
Cheng L, Zhang K, Qing Y, Li D, Cui M, Jin P, Xu T
Journal of ovarian research 2020 Jan 22;13(1):9
Journal of ovarian research 2020 Jan 22;13(1):9
Inhibitory Activity of a Scorpion Defensin BmKDfsin3 against Hepatitis C Virus.
Cheng Y, Sun F, Li S, Gao M, Wang L, Sarhan M, Abdel-Rahman MA, Li W, Kwok HF, Wu Y, Cao Z
Antibiotics (Basel, Switzerland) 2020 Jan 17;9(1)
Antibiotics (Basel, Switzerland) 2020 Jan 17;9(1)
Photocrosslinking Activity-Based Probes for Ubiquitin RING E3 Ligases.
Mathur S, Fletcher AJ, Branigan E, Hay RT, Virdee S
Cell chemical biology 2020 Jan 16;27(1):74-82.e6
Cell chemical biology 2020 Jan 16;27(1):74-82.e6
Dysregulation of BDNF/TrkB signaling mediated by NMDAR/Ca2+/calpain might contribute to postoperative cognitive dysfunction in aging mice.
Qiu LL, Pan W, Luo D, Zhang GF, Zhou ZQ, Sun XY, Yang JJ, Ji MH
Journal of neuroinflammation 2020 Jan 16;17(1):23
Journal of neuroinflammation 2020 Jan 16;17(1):23
High RhCG expression predicts poor survival and promotes migration and proliferation of gastric cancer via keeping intracellular alkaline.
Chen P, Liu C, Li P, Wang Q, Gao X, Wu H, Huang J
Experimental cell research 2020 Jan 15;386(2):111740
Experimental cell research 2020 Jan 15;386(2):111740
linc01088 promotes cell proliferation by scaffolding EZH2 and repressing p21 in human non-small cell lung cancer.
Liu JQ, Feng YH, Zeng S, Zhong MZ
Life sciences 2020 Jan 15;241:117134
Life sciences 2020 Jan 15;241:117134
Intermittent hypoxia mediated by TSP1 dependent on STAT3 induces cardiac fibroblast activation and cardiac fibrosis.
Bao Q, Zhang B, Suo Y, Liu C, Yang Q, Zhang K, Yuan M, Yuan M, Zhang Y, Li G
eLife 2020 Jan 14;9
eLife 2020 Jan 14;9
Targeting 7-Dehydrocholesterol Reductase Integrates Cholesterol Metabolism and IRF3 Activation to Eliminate Infection.
Xiao J, Li W, Zheng X, Qi L, Wang H, Zhang C, Wan X, Zheng Y, Zhong R, Zhou X, Lu Y, Li Z, Qiu Y, Liu C, Zhang F, Zhang Y, Xu X, Yang Z, Chen H, Zhai Q, Wei B, Wang H
Immunity 2020 Jan 14;52(1):109-122.e6
Immunity 2020 Jan 14;52(1):109-122.e6
Impact of GFRA1 gene reactivation by DNA demethylation on prognosis of patients with metastatic colon cancer.
Ma WR, Xu P, Liu ZJ, Zhou J, Gu LK, Zhang J, Deng DJ
World journal of gastroenterology 2020 Jan 14;26(2):184-198
World journal of gastroenterology 2020 Jan 14;26(2):184-198
Synaptic density marker SV2A is reduced in schizophrenia patients and unaffected by antipsychotics in rats.
Onwordi EC, Halff EF, Whitehurst T, Mansur A, Cotel MC, Wells L, Creeney H, Bonsall D, Rogdaki M, Shatalina E, Reis Marques T, Rabiner EA, Gunn RN, Natesan S, Vernon AC, Howes OD
Nature communications 2020 Jan 14;11(1):246
Nature communications 2020 Jan 14;11(1):246
FHL3 promotes pancreatic cancer invasion and metastasis through preventing the ubiquitination degradation of EMT associated transcription factors.
Li P, Cao G, Zhang Y, Shi J, Cai K, Zhen L, He X, Zhou Y, Li Y, Zhu Y, Xiong M, Wu Y
Aging 2020 Jan 13;12(1):53-69
Aging 2020 Jan 13;12(1):53-69
Endogenous production of C-C motif chemokine ligand 2 by nasopharyngeal carcinoma cells drives radioresistance-associated metastasis.
Guo SS, Liu R, Wen YF, Liu LT, Yuan L, Li YX, Li Y, Hao WW, Peng JY, Chen DN, Tang QN, Sun XS, Guo L, Mo HY, Qian CN, Zeng MS, Bei JX, Sun SY, Chen QY, Tang LQ, Mai HQ
Cancer letters 2020 Jan 1;468:27-40
Cancer letters 2020 Jan 1;468:27-40
Yap/Taz are required for establishing the cerebellar radial glia scaffold and proper foliation.
Hughes LJ, Park R, Lee MJ, Terry BK, Lee DJ, Kim H, Cho SH, Kim S
Developmental biology 2020 Jan 1;457(1):150-162
Developmental biology 2020 Jan 1;457(1):150-162
Endothelial microvesicles induced by physiological cyclic stretch inhibit ICAM1-Dependent leukocyte adhesion.
Zhuang F, Shi Q, Wang WB, Bao H, Yan J, Gao S, Liu Z, Jiang ZL, Qi YX
Experimental cell research 2020 Jan 1;386(1):111710
Experimental cell research 2020 Jan 1;386(1):111710
miR-181b-5p inhibits endothelial-mesenchymal transition in monocrotaline-induced pulmonary arterial hypertension by targeting endocan and TGFBR1.
Zhao H, Wang Y, Zhang X, Guo Y, Wang X
Toxicology and applied pharmacology 2020 Jan 1;386:114827
Toxicology and applied pharmacology 2020 Jan 1;386:114827
Hepatitis B virus-triggered PTEN/β-catenin/c-Myc signaling enhances PD-L1 expression to promote immune evasion.
Sun Y, Yu M, Qu M, Ma Y, Zheng D, Yue Y, Guo S, Tang L, Li G, Zheng W, Wang M, Guo D, Li C
American journal of physiology. Gastrointestinal and liver physiology 2020 Jan 1;318(1):G162-G173
American journal of physiology. Gastrointestinal and liver physiology 2020 Jan 1;318(1):G162-G173
Role of the autotaxin-lysophosphatidic acid axis in glaucoma, aqueous humor drainage and fibrogenic activity.
Ho LTY, Osterwald A, Ruf I, Hunziker D, Mattei P, Challa P, Vann R, Ullmer C, Rao PV
Biochimica et biophysica acta. Molecular basis of disease 2020 Jan 1;1866(1):165560
Biochimica et biophysica acta. Molecular basis of disease 2020 Jan 1;1866(1):165560
Attenuation of secondary damage and Aβ deposits in the ipsilateral thalamus of dMCAO rats through reduction of cathepsin B by bis(propyl)-cognitin, a multifunctional dimer.
Zuo X, Hu S, Tang Y, Zhan L, Sun W, Zheng J, Han Y, Xu E
Neuropharmacology 2020 Jan 1;162:107786
Neuropharmacology 2020 Jan 1;162:107786
Decreased DHRS2 expression is associated with HDACi resistance and poor prognosis in ovarian cancer.
Han Y, Wang Z, Sun S, Zhang Z, Liu J, Jin X, Wu P, Ji T, Ding W, Wang B, Gao Q
Epigenetics 2020 Jan - Feb;15(1-2):122-133
Epigenetics 2020 Jan - Feb;15(1-2):122-133
Identification of chemoresistance-related mRNAs based on gemcitabine-resistant pancreatic cancer cell lines.
Zhou J, Zhang L, Zheng H, Ge W, Huang Y, Yan Y, Zhou X, Zhu W, Kong Y, Ding Y, Wang W
Cancer medicine 2020 Feb;9(3):1115-1130
Cancer medicine 2020 Feb;9(3):1115-1130
Interferon gamma inhibits CXCL8-CXCR2 axis mediated tumor-associated macrophages tumor trafficking and enhances anti-PD1 efficacy in pancreatic cancer.
Zhang M, Huang L, Ding G, Huang H, Cao G, Sun X, Lou N, Wei Q, Shen T, Xu X, Cao L, Yan Q
Journal for immunotherapy of cancer 2020 Feb;8(1)
Journal for immunotherapy of cancer 2020 Feb;8(1)
The key role of macrophage depolarization in the treatment of COPD with ergosterol both in vitro and in vivo.
Sun X, Liu Y, Feng X, Li C, Li S, Zhao Z
International immunopharmacology 2020 Feb;79:106086
International immunopharmacology 2020 Feb;79:106086
LL-37 restored glucocorticoid sensitivity impaired by virus dsRNA in lung.
Li K, Tao N, Zheng L, Sun T
International immunopharmacology 2020 Feb;79:106057
International immunopharmacology 2020 Feb;79:106057
Icariside II improves myocardial fibrosis in spontaneously hypertensive rats by inhibiting collagen synthesis.
Fu S, Li Y, Wu Y, Yue Y, Yang D
The Journal of pharmacy and pharmacology 2020 Feb;72(2):227-235
The Journal of pharmacy and pharmacology 2020 Feb;72(2):227-235
Activation of CRHR1 contributes to cerebral endothelial barrier impairment via cPLA2 phosphorylation in experimental ischemic stroke.
Cao C, Zhou J, Wu X, Qian Y, Hong Y, Mu J, Jin L, Zhu C, Li S
Cellular signalling 2020 Feb;66:109467
Cellular signalling 2020 Feb;66:109467
Alveolar Stretch Activation of Endothelial Piezo1 Protects Adherens Junctions and Lung Vascular Barrier.
Zhong M, Wu W, Kang H, Hong Z, Xiong S, Gao X, Rehman J, Komarova YA, Malik AB
American journal of respiratory cell and molecular biology 2020 Feb;62(2):168-177
American journal of respiratory cell and molecular biology 2020 Feb;62(2):168-177
Long non‑coding RNA CASC2 suppresses pancreatic cancer cell growth and progression by regulating the miR‑24/MUC6 axis.
Xu DF, Wang LS, Zhou JH
International journal of oncology 2020 Feb;56(2):494-507
International journal of oncology 2020 Feb;56(2):494-507
Epiregulin promotes trophoblast epithelial-mesenchymal transition through poFUT1 and O-fucosylation by poFUT1 on uPA.
Cui X, Wang H, Li Y, Chen T, Liu S, Yan Q
Cell proliferation 2020 Feb;53(2):e12745
Cell proliferation 2020 Feb;53(2):e12745
Long noncoding RNA NEAT1 is involved in the protective effect of Klotho on renal tubular epithelial cells in diabetic kidney disease through the ERK1/2 signaling pathway.
Yang YL, Xue M, Jia YJ, Hu F, Zheng ZJ, Wang L, Si ZK, Xue YM
Experimental & molecular medicine 2020 Feb;52(2):266-280
Experimental & molecular medicine 2020 Feb;52(2):266-280
miR-1294 alleviates epithelial-mesenchymal transition by repressing FOXK1 in gastric cancer.
Wang Y, Liu G, Sun S, Qin J
Genes & genomics 2020 Feb;42(2):217-224
Genes & genomics 2020 Feb;42(2):217-224
EPHA2 feedback activation limits the response to PDEδ inhibition in KRAS-dependent cancer cells.
Chen YH, Lv H, Shen N, Wang XM, Tang S, Xiong B, Ding J, Geng MY, Huang M
Acta pharmacologica Sinica 2020 Feb;41(2):270-277
Acta pharmacologica Sinica 2020 Feb;41(2):270-277
A lncRNA coordinates with Ezh2 to inhibit HIF-1α transcription and suppress cancer cell adaption to hypoxia.
Wang X, Wang Y, Li L, Xue X, Xie H, Shi H, Hu Y
Oncogene 2020 Feb;39(9):1860-1874
Oncogene 2020 Feb;39(9):1860-1874
RBBP8/CtIP suppresses P21 expression by interacting with CtBP and BRCA1 in gastric cancer.
Yu Y, Chen L, Zhao G, Li H, Guo Q, Zhu S, Li P, Min L, Zhang S
Oncogene 2020 Feb;39(6):1273-1289
Oncogene 2020 Feb;39(6):1273-1289
Comparative Transcriptome Analysis Reveals Different Host Cell Responses to Acute and Persistent Foot-and-Mouth Disease Virus Infection.
Li J, Han L, Hao Y, Yuan Y, Wang M, Xin X, Wang H, Yu F, Zheng C, Shen C
Virologica Sinica 2020 Feb;35(1):52-63
Virologica Sinica 2020 Feb;35(1):52-63
Histone deacetylase 6 inhibition restores autophagic flux to promote functional recovery after spinal cord injury.
Zheng Z, Zhou Y, Ye L, Lu Q, Zhang K, Zhang J, Xie L, Wu Y, Xu K, Zhang H, Xiao J
Experimental neurology 2020 Feb;324:113138
Experimental neurology 2020 Feb;324:113138
Bisphenol A Exposure Enhances Endometrial Stromal Cell Invasion and Has a Positive Association with Peritoneal Endometriosis.
Wen X, Xiong Y, Jin L, Zhang M, Huang L, Mao Y, Zhou C, Qiao Y, Zhang Y
Reproductive sciences (Thousand Oaks, Calif.) 2020 Feb;27(2):704-712
Reproductive sciences (Thousand Oaks, Calif.) 2020 Feb;27(2):704-712
HSF1 promotes the viability of islet β-cells via upregulating SIRPα expression.
Zhang HM, Yang M, Zhang XY, Tang Y, Wu JL, Huang J
European review for medical and pharmacological sciences 2020 Feb;24(4):1939-1947
European review for medical and pharmacological sciences 2020 Feb;24(4):1939-1947
N-glycosylation of uterine endometrium determines its receptivity.
Yu M, Qin H, Wang H, Liu J, Liu S, Yan Q
Journal of cellular physiology 2020 Feb;235(2):1076-1089
Journal of cellular physiology 2020 Feb;235(2):1076-1089
Protocatechuic Aldehyde Represses Proliferation and Migration of Breast Cancer Cells through Targeting C-terminal Binding Protein 1.
Deng Y, Guo W, Li G, Li S, Li H, Li X, Niu B, Song M, Zhang Y, Xu Z, Li F
Journal of breast cancer 2020 Feb;23(1):20-35
Journal of breast cancer 2020 Feb;23(1):20-35
Chidamide induces necroptosis via regulation of c‑FLIPL expression in Jurkat and HUT‑78 cells.
Chi Z, Gao H, Liu H, Wu B, Zhang B, Gu M, Yang W
Molecular medicine reports 2020 Feb;21(2):936-944
Molecular medicine reports 2020 Feb;21(2):936-944
miR‑337‑3p inhibits gastric tumor metastasis by targeting ARHGAP10.
Wang Z, Yao L, Li Y, Hao B, Wang M, Wang J, Gu W, Zhan H, Liu G, Wu Q
Molecular medicine reports 2020 Feb;21(2):705-719
Molecular medicine reports 2020 Feb;21(2):705-719
HDAC11 promotes meiotic apparatus assembly during mouse oocyte maturation via decreasing H4K16 and α-tubulin acetylation.
Sui L, Zhang S, Huang R, Li Z
Cell cycle (Georgetown, Tex.) 2020 Feb;19(3):354-362
Cell cycle (Georgetown, Tex.) 2020 Feb;19(3):354-362
α-synuclein promotes progression of Parkinson's disease by upregulating autophagy signaling pathway to activate NLRP3 inflammasome.
Wang X, Chi J, Huang D, Ding L, Zhao X, Jiang L, Yu Y, Gao F
Experimental and therapeutic medicine 2020 Feb;19(2):931-938
Experimental and therapeutic medicine 2020 Feb;19(2):931-938
BMP4 induces asymmetric cell division in human glioma stem-like cells.
Koguchi M, Nakahara Y, Ito H, Wakamiya T, Yoshioka F, Ogata A, Inoue K, Masuoka J, Izumi H, Abe T
Oncology letters 2020 Feb;19(2):1247-1254
Oncology letters 2020 Feb;19(2):1247-1254
Maternal exposure to fine particle matters cause autophagy via UPR-mediated PI3K-mTOR pathway in testicular tissue of adult male mice in offspring.
Ren L, Huang J, Wei J, Zang Y, Zhao Y, Wu S, Zhao X, Zhou X, Sun Z, Lu H
Ecotoxicology and environmental safety 2020 Feb;189:109943
Ecotoxicology and environmental safety 2020 Feb;189:109943
Capping Protein Regulator and Myosin 1 Linker 3 Is Required for Tumor Metastasis.
Wang H, Wang C, Peng G, Yu D, Cui XG, Sun YH, Ma X
Molecular cancer research : MCR 2020 Feb;18(2):240-252
Molecular cancer research : MCR 2020 Feb;18(2):240-252
3-Mercaptopyruvate sulfurtransferase supports endothelial cell angiogenesis and bioenergetics.
Abdollahi Govar A, Törő G, Szaniszlo P, Pavlidou A, Bibli SI, Thanki K, Resto VA, Chao C, Hellmich MR, Szabo C, Papapetropoulos A, Módis K
British journal of pharmacology 2020 Feb;177(4):866-883
British journal of pharmacology 2020 Feb;177(4):866-883
Retinoic acid receptor gamma is targeted by microRNA-124 and inhibits neurite outgrowth.
Su X, Gu X, Zhang Z, Li W, Wang X
Neuropharmacology 2020 Feb;163:107657
Neuropharmacology 2020 Feb;163:107657
Proteomics profiling of epithelium-derived exosomes from nasal polyps revealed signaling functions affecting cellular proliferation.
Zhou M, Tan KS, Guan WJ, Jiang LJ, Deng J, Gao WX, Lee YM, Xu ZF, Luo X, Liu C, Shi JB, Lai Y
Respiratory medicine 2020 Feb;162:105871
Respiratory medicine 2020 Feb;162:105871
Arfgef1 haploinsufficiency in mice alters neuronal endosome composition and decreases membrane surface postsynaptic GABAA receptors.
Teoh J, Subramanian N, Pero ME, Bartolini F, Amador A, Kanber A, Williams D, Petri S, Yang M, Allen AS, Beal J, Haut SR, Frankel WN
Neurobiology of disease 2020 Feb;134:104632
Neurobiology of disease 2020 Feb;134:104632
The role of invariant natural killer T cells in experimental xenobiotic-induced cholestatic hepatotoxicity.
Nong C, Zou M, Xue R, Bai L, Liu L, Jiang Z, Sun L, Huang X, Zhang L, Wang X
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Feb;122:109579
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Feb;122:109579
lncRNA SNHG3 facilitates acute myeloid leukemia cell growth via the regulation of miR-758-3p/SRGN axis.
Peng L, Zhang Y, Xin H
Journal of cellular biochemistry 2020 Feb;121(2):1023-1031
Journal of cellular biochemistry 2020 Feb;121(2):1023-1031
A risk prediction model of DNA methylation improves prognosis evaluation and indicates gene targets in prostate cancer.
Zhang E, Hou X, Hou B, Zhang M, Song Y
Epigenomics 2020 Feb;12(4):333-352
Epigenomics 2020 Feb;12(4):333-352
Ubiquitination of NOTCH2 by DTX3 suppresses the proliferation and migration of human esophageal carcinoma.
Ding XY, Hu HY, Huang KN, Wei RQ, Min J, Qi C, Tang H, Qin X
Cancer science 2020 Feb;111(2):489-501
Cancer science 2020 Feb;111(2):489-501
3-O-Acetyl-11-keto- β -boswellic acid ameliorated aberrant metabolic landscape and inhibited autophagy in glioblastoma.
Li W, Ren L, Zheng X, Liu J, Wang J, Ji T, Du G
Acta pharmaceutica Sinica. B 2020 Feb;10(2):301-312
Acta pharmaceutica Sinica. B 2020 Feb;10(2):301-312
FAM172A inhibits EMT in pancreatic cancer via ERK-MAPK signaling.
Chen Y, Liu P, Shen D, Liu H, Xu L, Wang J, Shen D, Sun H, Wu H
Biology open 2020 Feb 7;9(2)
Biology open 2020 Feb 7;9(2)
Systematic Comparison of Label-Free, SILAC, and TMT Techniques to Study Early Adaption toward Inhibition of EGFR Signaling in the Colorectal Cancer Cell Line DiFi.
Stepath M, Zülch B, Maghnouj A, Schork K, Turewicz M, Eisenacher M, Hahn S, Sitek B, Bracht T
Journal of proteome research 2020 Feb 7;19(2):926-937
Journal of proteome research 2020 Feb 7;19(2):926-937
Extracellular nanofiber-orchestrated cytoskeletal reorganization and mediated directional migration of cancer cells.
Wang Y, Gong J, Yao Y
Nanoscale 2020 Feb 7;12(5):3183-3193
Nanoscale 2020 Feb 7;12(5):3183-3193
DGCR8/ZFAT-AS1 Promotes CDX2 Transcription in a PRC2 Complex-Dependent Manner to Facilitate the Malignant Biological Behavior of Glioma Cells.
Zhang F, Ruan X, Ma J, Liu X, Zheng J, Liu Y, Liu L, Shen S, Shao L, Wang D, Yang C, Cai H, Li Z, Feng Z, Xue Y
Molecular therapy : the journal of the American Society of Gene Therapy 2020 Feb 5;28(2):613-630
Molecular therapy : the journal of the American Society of Gene Therapy 2020 Feb 5;28(2):613-630
The Fluoro-Thiazolylhydrazone Compound TSC-3C Inhibits Triple Negative Breast Cancer (TNBC) Cell Line Activity by Promoting Apoptosis, Regulating the MAPK Pathway and Inducing Mitochondrial Dysfunction.
Zhang J, Dai J, Zheng Q, Guo S, Yu Y, Hu W, Gao Y, Shi D
International journal of molecular sciences 2020 Feb 4;21(3)
International journal of molecular sciences 2020 Feb 4;21(3)
Protective properties of heme oxygenase-1 expressed in umbilical cord mesenchymal stem cells help restore the ovarian function of premature ovarian failure mice through activating the JNK/Bcl-2 signal pathway-regulated autophagy and upregulating the circulating of CD8+CD28- T cells.
Yin N, Wu C, Qiu J, Zhang Y, Bo L, Xu Y, Shi M, Zhu S, Yang G, Mao C
Stem cell research & therapy 2020 Feb 4;11(1):49
Stem cell research & therapy 2020 Feb 4;11(1):49
A DNAH17 missense variant causes flagella destabilization and asthenozoospermia.
Zhang B, Ma H, Khan T, Ma A, Li T, Zhang H, Gao J, Zhou J, Li Y, Yu C, Bao J, Ali A, Murtaza G, Yin H, Gao Q, Jiang X, Zhang F, Liu C, Khan I, Zubair M, Hussain HMJ, Khan R, Yousaf A, Yuan L, Lu Y, Xu X, Wang Y, Tao Q, Hao Q, Fang H, Cheng H, Zhang Y, Shi Q
The Journal of experimental medicine 2020 Feb 3;217(2)
The Journal of experimental medicine 2020 Feb 3;217(2)
Mevalonate metabolism-dependent protein geranylgeranylation regulates thymocyte egress.
Du X, Zeng H, Liu S, Guy C, Dhungana Y, Neale G, Bergo MO, Chi H
The Journal of experimental medicine 2020 Feb 3;217(2)
The Journal of experimental medicine 2020 Feb 3;217(2)
Differential effects of Chinese high-fat dietary habits on lipid metabolism: mechanisms and health implications.
Yan S, Zhou H, Liu S, Wang J, Zeng Y, Matias FB, Wen L
Lipids in health and disease 2020 Feb 29;19(1):30
Lipids in health and disease 2020 Feb 29;19(1):30
Downregulation of lung miR-203a-3p expression by high-altitude hypoxia enhances VEGF/Notch signaling.
Cai W, Liu S, Liu Z, Hou S, Lv Q, Cui H, Wang X, Zhang Y, Fan H, Ding H
Aging 2020 Feb 29;12(5):4247-4267
Aging 2020 Feb 29;12(5):4247-4267
SOX2 Represses Hepatitis B Virus Replication by Binding to the Viral EnhII/Cp and Inhibiting the Promoter Activation.
Yang H, Mo J, Xiang Q, Zhao P, Song Y, Yang G, Wu K, Liu Y, Liu W, Wu J
Viruses 2020 Feb 29;12(3)
Viruses 2020 Feb 29;12(3)
FKBP9 promotes the malignant behavior of glioblastoma cells and confers resistance to endoplasmic reticulum stress inducers.
Xu H, Liu P, Yan Y, Fang K, Liang D, Hou X, Zhang X, Wu S, Ma J, Wang R, Li T, Piao H, Meng S
Journal of experimental & clinical cancer research : CR 2020 Feb 28;39(1):44
Journal of experimental & clinical cancer research : CR 2020 Feb 28;39(1):44
Assessment of Prolonged Dengue Virus Infection in Dermal Fibroblasts and Hair-Follicle Dermal Papilla Cells.
Wei KC, Wei WJ, Liu YS, Yen LC, Chang TH
Viruses 2020 Feb 28;12(3)
Viruses 2020 Feb 28;12(3)
Anti-inflammatory effects of Lactobacillus johnsonii L531 in a pig model of Salmonella Infantis infection involves modulation of CCR6+ T cell responses and ER stress.
Yang GY, Xia B, Su JH, He T, Liu X, Guo L, Zhang S, Zhu YH, Wang JF
Veterinary research 2020 Feb 24;51(1):26
Veterinary research 2020 Feb 24;51(1):26
The behavioural and neuropathologic sexual dimorphism and absence of MIP-3α in tau P301S mouse model of Alzheimer's disease.
Sun Y, Guo Y, Feng X, Jia M, Ai N, Dong Y, Zheng Y, Fu L, Yu B, Zhang H, Wu J, Yu X, Wu H, Kong W
Journal of neuroinflammation 2020 Feb 24;17(1):72
Journal of neuroinflammation 2020 Feb 24;17(1):72
Rumen-Protected Glucose Stimulates the Insulin-Like Growth Factor System and mTOR/AKT Pathway in the Endometrium of Early Postpartum Dairy Cows.
Wang Y, Han X, Tan Z, Kang J, Wang Z
Animals : an open access journal from MDPI 2020 Feb 23;10(2)
Animals : an open access journal from MDPI 2020 Feb 23;10(2)
Structural Basis for Inhibiting Porcine Epidemic Diarrhea Virus Replication with the 3C-Like Protease Inhibitor GC376.
Ye G, Wang X, Tong X, Shi Y, Fu ZF, Peng G
Viruses 2020 Feb 21;12(2)
Viruses 2020 Feb 21;12(2)
Modulation of in vitro Brain Endothelium by Mechanical Trauma: Structural and Functional Restoration by Poloxamer 188.
Inyang E, Abhyankar V, Chen B, Cho M
Scientific reports 2020 Feb 20;10(1):3054
Scientific reports 2020 Feb 20;10(1):3054
A Novel Role for PX, a Structural Protein of Fowl Adenovirus Serotype 4 (FAdV4), as an Apoptosis-Inducer in Leghorn Male Hepatocellular Cell.
Zhao M, Duan X, Wang Y, Gao L, Cao H, Li X, Zheng SJ
Viruses 2020 Feb 18;12(2)
Viruses 2020 Feb 18;12(2)
Targeted overexpression of the long noncoding RNA ODSM can regulate osteoblast function in vitro and in vivo.
Wang Y, Wang K, Zhang L, Tan Y, Hu Z, Dang L, Zhou H, Li G, Wang H, Zhang S, Shi F, Cao X, Zhang G
Cell death & disease 2020 Feb 18;11(2):133
Cell death & disease 2020 Feb 18;11(2):133
Generation of a self-cleaved inducible Cre recombinase for efficient temporal genetic manipulation.
Tian X, He L, Liu K, Pu W, Zhao H, Li Y, Liu X, Tang M, Sun R, Fei J, Ji Y, Qiao Z, Lui KO, Zhou B
The EMBO journal 2020 Feb 17;39(4):e102675
The EMBO journal 2020 Feb 17;39(4):e102675
Overcoming cisplatin resistance by targeting the MTDH-PTEN interaction in ovarian cancer with sera derived from rats exposed to Guizhi Fuling wan extract.
Han L, Cao X, Chen Z, Guo X, Yang L, Zhou Y, Bian H
BMC complementary medicine and therapies 2020 Feb 17;20(1):57
BMC complementary medicine and therapies 2020 Feb 17;20(1):57
Dynasore potentiates c-Met inhibitors against hepatocellular carcinoma through destabilizing c-Met.
Zaky MY, Liu X, Wang T, Wang S, Liu F, Wang D, Wu Y, Zhang Y, Guo D, Sun Q, Li Q, Zhang J, Zhang Y, Dong W, Liu Z, Liu S, Liu H
Archives of biochemistry and biophysics 2020 Feb 15;680:108239
Archives of biochemistry and biophysics 2020 Feb 15;680:108239
GRWD1 promotes cell proliferation and migration in non-small cell lung cancer by activating the Notch pathway.
Wang Q, Ren H, Xu Y, Jiang J, Wudu M, Liu Z, Su H, Jiang X, Zhang Y, Zhang B, Qiu X
Experimental cell research 2020 Feb 15;387(2):111806
Experimental cell research 2020 Feb 15;387(2):111806
Extracellular vesicles transmitted miR-31-5p promotes sorafenib resistance by targeting MLH1 in renal cell carcinoma.
He J, He J, Min L, He Y, Guan H, Wang J, Peng X
International journal of cancer 2020 Feb 15;146(4):1052-1063
International journal of cancer 2020 Feb 15;146(4):1052-1063
Down-regulation of CCR7 via AKT pathway and GATA2 inactivation suppressed trophoblast migration and invasion in recurrent spontaneous abortion†.
Luan X, Li S, Zhao J, Zhai J, Liu X, Chen ZJ, Li W, Du Y
Biology of reproduction 2020 Feb 14;102(2):424-433
Biology of reproduction 2020 Feb 14;102(2):424-433
Entorhinal cortex-based metabolic profiling of chronic restraint stress mice model of depression.
Chen X, Lan T, Wang Y, He Y, Wu Z, Tian Y, Li Y, Bai M, Zhou W, Zhang H, Cheng K, Xie P
Aging 2020 Feb 12;12(3):3042-3052
Aging 2020 Feb 12;12(3):3042-3052
Level of N6-Methyladenosine in Peripheral Blood RNA: A Novel Predictive Biomarker for Gastric Cancer.
Ge L, Zhang N, Chen Z, Song J, Wu Y, Li Z, Chen F, Wu J, Li D, Li J, Wang C, Wang H, Wang J
Clinical chemistry 2020 Feb 1;66(2):342-351
Clinical chemistry 2020 Feb 1;66(2):342-351
Sodium butyrate causes α-synuclein degradation by an Atg5-dependent and PI3K/Akt/mTOR-related autophagy pathway.
Qiao CM, Sun MF, Jia XB, Shi Y, Zhang BP, Zhou ZL, Zhao LP, Cui C, Shen YQ
Experimental cell research 2020 Feb 1;387(1):111772
Experimental cell research 2020 Feb 1;387(1):111772
Nucleostemin promotes hepatocellular carcinoma by regulating the function of STAT3.
Zhang X, Lv J, Luo H, Liu Z, Xu C, Zhou D, Tang L, Zhang Z, Liu J, Xiao M, Yao Y, Qu L, Lu C
Experimental cell research 2020 Feb 1;387(1):111748
Experimental cell research 2020 Feb 1;387(1):111748
Silencing of DsbA-L gene impairs the PPARγ agonist function of improving insulin resistance in a high-glucose cell model.
Zhou X, Li JQ, Wei LJ, He MZ, Jia J, Zhang JY, Wang SS, Feng L
Journal of Zhejiang University. Science. B 2020 Dec.;21(12):990-998
Journal of Zhejiang University. Science. B 2020 Dec.;21(12):990-998
Autotaxin stimulates LPA2 receptor in macrophages and exacerbates dextran sulfate sodium-induced acute colitis.
Wang Z, Shi W, Tian D, Qin H, Vallance BA, Yang H, Yu HB, Yu Q
Journal of molecular medicine (Berlin, Germany) 2020 Dec;98(12):1781-1794
Journal of molecular medicine (Berlin, Germany) 2020 Dec;98(12):1781-1794
Neuron-derived factors negatively modulate ryanodine receptor-mediated calcium release in cultured mouse astrocytes.
Skowrońska K, Kozłowska H, Albrecht J
Cell calcium 2020 Dec;92:102304
Cell calcium 2020 Dec;92:102304
Inhibition of PI3K/Akt/NF-κB signaling by Aloin for ameliorating the progression of osteoarthritis: In vitro and in vivo studies.
Zhang C, Shao Z, Hu X, Chen Z, Li B, Jiang R, Bsoul N, Chen J, Xu C, Gao W
International immunopharmacology 2020 Dec;89(Pt B):107079
International immunopharmacology 2020 Dec;89(Pt B):107079
Protective effect of taraxasterol on ischemia/reperfusion-induced acute kidney injury via inhibition of oxidative stress, inflammation, and apoptosis.
Li C, Zheng Z, Xie Y, Zhu N, Bao J, Yu Q, Zhou Z, Liu J
International immunopharmacology 2020 Dec;89(Pt A):107169
International immunopharmacology 2020 Dec;89(Pt A):107169
Inhibition of PCSK9 potentiates immune checkpoint therapy for cancer.
Liu X, Bao X, Hu M, Chang H, Jiao M, Cheng J, Xie L, Huang Q, Li F, Li CY
Nature 2020 Dec;588(7839):693-698
Nature 2020 Dec;588(7839):693-698
Structure of LRRK2 in Parkinson's disease and model for microtubule interaction.
Deniston CK, Salogiannis J, Mathea S, Snead DM, Lahiri I, Matyszewski M, Donosa O, Watanabe R, Böhning J, Shiau AK, Knapp S, Villa E, Reck-Peterson SL, Leschziner AE
Nature 2020 Dec;588(7837):344-349
Nature 2020 Dec;588(7837):344-349
Hepatoprotective effects of Camellia nitidissima aqueous ethanol extract against CCl4-induced acute liver injury in SD rats related to Nrf2 and NF-κB signalling.
Zhang X, Feng J, Su S, Huang L
Pharmaceutical biology 2020 Dec;58(1):239-246
Pharmaceutical biology 2020 Dec;58(1):239-246
Hepatoprotective effect of Xiayuxue decoction ethyl acetate fraction against carbon tetrachloride-induced liver fibrosis in mice via inducing apoptosis and suppressing activation of hepatic stellate cells.
Zhang D, Zhang L, Chen G, Xu Y, Yang H, Xiao Z, Chen J, Mu Y, Zhang H, Liu W, Liu P
Pharmaceutical biology 2020 Dec;58(1):1229-1243
Pharmaceutical biology 2020 Dec;58(1):1229-1243
Hypermethylation-mediated silencing of NDRG4 promotes pancreatic ductal adenocarcinoma by regulating mitochondrial function.
Shi HH, Liu HE, Luo XJ
BMB reports 2020 Dec;53(12):658-663
BMB reports 2020 Dec;53(12):658-663
Anti-tumour activity of zinc ionophore pyrithione in human ovarian cancer cells through inhibition of proliferation and migration and promotion of lysosome-mitochondrial apoptosis.
Chen M, Ding Y, Ke Y, Zeng Y, Liu N, Zhong Y, Hua X, Li Z, Xiong Y, Wu C, Yu H
Artificial cells, nanomedicine, and biotechnology 2020 Dec;48(1):824-833
Artificial cells, nanomedicine, and biotechnology 2020 Dec;48(1):824-833
Circ_0079593 facilitates proliferation, metastasis, glucose metabolism and inhibits apoptosis in melanoma by regulating the miR-516b/GRM3 axis.
Lu J, Li Y
Molecular and cellular biochemistry 2020 Dec;475(1-2):227-237
Molecular and cellular biochemistry 2020 Dec;475(1-2):227-237
Modulation of miRNAs by vitamin C in H2O2‑exposed human umbilical vein endothelial cells.
Wu J, Liang J, Li M, Lin M, Mai L, Huang X, Liang J, Hu Y, Huang Y
International journal of molecular medicine 2020 Dec;46(6):2150-2160
International journal of molecular medicine 2020 Dec;46(6):2150-2160
The protective effects of umbilical cord-derived endothelial colony forming cells on hepatic veno-occlusive disease.
Chen L, Zhang J, Liu X, Yao M, Zhang H
Cell biology international 2020 Dec;44(12):2541-2552
Cell biology international 2020 Dec;44(12):2541-2552
Tumor cell-expressed IL-15Rα drives antagonistic effects on the progression and immune control of gastric cancer and is epigenetically regulated in EBV-positive gastric cancer.
Wei J, Guo C, An X, Miao W, Zhang C, Wang B, Cai W, Li M, Zhang F
Cellular oncology (Dordrecht) 2020 Dec;43(6):1085-1097
Cellular oncology (Dordrecht) 2020 Dec;43(6):1085-1097
Aberrant expression of miRNA-192-5p contributes to N,N-dimethylformamide-induced hepatic apoptosis.
Zhang Z, Zhu W, Liu Z, Liu Y, Chang C, Jiang H, Li R, Xiao Y, Chen W, Hu Q, Wang Q
Journal of applied toxicology : JAT 2020 Dec;40(12):1683-1693
Journal of applied toxicology : JAT 2020 Dec;40(12):1683-1693
Upregulated miR-101 inhibits acute kidney injury-chronic kidney disease transition by regulating epithelial-mesenchymal transition.
Zhao JY, Wang XL, Yang YC, Zhang B, Wu YB
Human & experimental toxicology 2020 Dec;39(12):1628-1638
Human & experimental toxicology 2020 Dec;39(12):1628-1638
The kinesin motor protein KIF4A as a potential therapeutic target in renal cell carcinoma.
Liu G, Lu Y, Li L, Jiang T, Chu S, Hou P, Bai J, Chen M
Investigational new drugs 2020 Dec;38(6):1730-1742
Investigational new drugs 2020 Dec;38(6):1730-1742
Promotion of esophageal adenocarcinoma metastasis via Wnt/ß-catenin signal pathway by sorting nexins 3.
Pan B, Liu L, Hu X, Sun X, Zhu Y, Zhang T, Wei D, Guo Y, Shan J
Journal of gastroenterology and hepatology 2020 Dec;35(12):2131-2139
Journal of gastroenterology and hepatology 2020 Dec;35(12):2131-2139
Chondroitin synthase-3 regulates nucleus pulposus degeneration through actin-induced YAP signaling.
Wei L, Cao P, Xu C, Zhong H, Wang X, Bai M, Hu B, Wang R, Liu N, Tian Y, Chen H, Li J, Yuan W
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Dec;34(12):16581-16600
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Dec;34(12):16581-16600
Polyphyllin I attenuates cognitive impairments and reduces AD-like pathology through CIP2A-PP2A signaling pathway in 3XTg-AD mice.
Zhou Y, Yang D, Chen H, Zheng C, Jiang H, Liu X, Huang X, Ye S, Song S, Jiang N, Zhao Z, Ma S, Ma J, Huang K, Chen C, Fan X, Gong Y, Wang X, Fan J, Liu R, Shentu Y
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Dec;34(12):16414-16431
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Dec;34(12):16414-16431
Cold-induced RNA-binding protein (CIRBP) regulates the expression of Src-associated during mitosis of 68 kDa (Sam68) and extracellular signal-regulated kinases (ERK) during heat stress-induced testicular injury.
Xu C, Ke D, Zou L, Li N, Wang Y, Fan X, Zhu C, Xia W
Reproduction, fertility, and development 2020 Dec;32(18):1357-1364
Reproduction, fertility, and development 2020 Dec;32(18):1357-1364
JMY expression by Sertoli cells contributes to mediating spermatogenesis in mice.
Liu Y, Fan J, Yan Y, Dang X, Zhao R, Xu Y, Ding Z
The FEBS journal 2020 Dec;287(24):5478-5497
The FEBS journal 2020 Dec;287(24):5478-5497
Platelet-derived microvesicles promote endothelial progenitor cell proliferation in intimal injury by delivering TGF-β1.
Yan J, Bao H, Fan YJ, Jiang ZL, Qi YX, Han Y
The FEBS journal 2020 Dec;287(23):5196-5217
The FEBS journal 2020 Dec;287(23):5196-5217
Maresin1 Promotes M2 Macrophage Polarization Through Peroxisome Proliferator-Activated Receptor-γ Activation to Expedite Resolution of Acute Lung Injury.
Qiao N, Lin Y, Wang Z, Chen JY, Ge YY, Yao SL, Gong J
The Journal of surgical research 2020 Dec;256:584-594
The Journal of surgical research 2020 Dec;256:584-594
Inhibition of porcine reproductive and respiratory syndrome virus by PKC inhibitor dequalinium chloride in vitro.
Liu X, Gao L, Zhao Q, Wang X, Yang C, Bi J, Yang R, Jin X, Lan R, Cui R, Wang X, Li W, Wang X, Yang Y, Yu X, Lin Y, Liu J, Yin G
Veterinary microbiology 2020 Dec;251:108913
Veterinary microbiology 2020 Dec;251:108913
Long noncoding RNA XIST regulates cardiomyocyte apoptosis by targeting miR-873-5p/MCL1 axis.
Cai CL, Jin L, Lang XL, Li BL
European review for medical and pharmacological sciences 2020 Dec;24(24):12878-12886
European review for medical and pharmacological sciences 2020 Dec;24(24):12878-12886
IGFBP6 regulates vascular smooth muscle cell proliferation and morphology via cyclin E-CDK2.
Wang Z, Qi Y, Wang R, Wu W, Li Z, Wang M, Liu R, Zhang C, Li W, Wang S
Journal of cellular physiology 2020 Dec;235(12):9538-9556
Journal of cellular physiology 2020 Dec;235(12):9538-9556
The proinflammatory cytokines IL-1β and TNF-α modulate corneal epithelial wound healing through p16Ink4a suppressing STAT3 activity.
Wang X, Zhang S, Dong M, Li Y, Zhou Q, Yang L
Journal of cellular physiology 2020 Dec;235(12):10081-10093
Journal of cellular physiology 2020 Dec;235(12):10081-10093
Sulforaphane suppresses polyinosinic‑polycytidylic acid‑stimulated release of cytokines, chemokines and MMPs by human corneal fibroblasts.
Liu P, Liu Y, Zheng H, Zheng X, Yang X, Zhao X, Chen L, Liu Y
Molecular medicine reports 2020 Dec;22(6):5463-5471
Molecular medicine reports 2020 Dec;22(6):5463-5471
miR‑124‑3p regulates angiogenesis in peripheral arterial disease by targeting STAT3.
Shi Y, Xu X, Luan P, Kou W, Li M, Yu Q, Zhuang J, Xu Y, Peng W, Jian W
Molecular medicine reports 2020 Dec;22(6):4890-4898
Molecular medicine reports 2020 Dec;22(6):4890-4898
Demethylation of HACE1 gene promoter by propofol promotes autophagy of human A549 cells.
Li S, Yang H, Zhao M, Gong L, Wang Y, Lv Z, Quan Y, Wang Z
Oncology letters 2020 Dec;20(6):280
Oncology letters 2020 Dec;20(6):280
Long noncoding RNA HAND2-AS1 reduced the viability of hepatocellular carcinoma via targeting microRNA-300/SOCS5 axis.
Bi HQ, Li ZH, Zhang H
Hepatobiliary & pancreatic diseases international : HBPD INT 2020 Dec;19(6):567-574
Hepatobiliary & pancreatic diseases international : HBPD INT 2020 Dec;19(6):567-574
UBR5 over-expression contributes to poor prognosis and tamoxifen resistance of ERa+ breast cancer by stabilizing β-catenin.
Yang Y, Zhao J, Mao Y, Lin G, Li F, Jiang Z
Breast cancer research and treatment 2020 Dec;184(3):699-710
Breast cancer research and treatment 2020 Dec;184(3):699-710
Loss of hepatic aldolase B activates Akt and promotes hepatocellular carcinogenesis by destabilizing the Aldob/Akt/PP2A protein complex.
He X, Li M, Yu H, Liu G, Wang N, Yin C, Tu Q, Narla G, Tao Y, Cheng S, Yin H
PLoS biology 2020 Dec;18(12):e3000803
PLoS biology 2020 Dec;18(12):e3000803
A spirostanol saponin isolated from Tupistra chinensis Baker simultaneously induces apoptosis and autophagy by regulating the JNK pathway in human gastric cancer cells.
Xu J, Wang Z, Huang Y, Wang Y, Xiang L, He X
Steroids 2020 Dec;164:108737
Steroids 2020 Dec;164:108737
LGR4 maintains HGSOC cell epithelial phenotype and stem-like traits.
Wang Z, Yin P, Sun Y, Na L, Gao J, Wang W, Zhao C
Gynecologic oncology 2020 Dec;159(3):839-849
Gynecologic oncology 2020 Dec;159(3):839-849
Pentraxin 3 contributes to neurogenesis after traumatic brain injury in mice.
Zhou C, Chen H, Zheng JF, Guo ZD, Huang ZJ, Wu Y, Zhong JJ, Sun XC, Cheng CJ
Neural regeneration research 2020 Dec;15(12):2318-2326
Neural regeneration research 2020 Dec;15(12):2318-2326
Glycogen synthase kinase-3β inhibition alleviates activation of the NLRP3 inflammasome in myocardial infarction.
Wang S, Su X, Xu L, Chang C, Yao Y, Komal S, Cha X, Zang M, Ouyang X, Zhang L, Han S
Journal of molecular and cellular cardiology 2020 Dec;149:82-94
Journal of molecular and cellular cardiology 2020 Dec;149:82-94
The role of invariant natural killer T cells and associated immunoregulatory factors in triptolide-induced cholestatic liver injury.
Zou M, Nong C, Yu Z, Cai H, Jiang Z, Xue R, Huang X, Sun L, Zhang L, Wang X
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2020 Dec;146:111777
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2020 Dec;146:111777
LINC00673 exerts oncogenic function in cervical cancer by negatively regulating miR-126-5p expression and activates PTEN/PI3K/AKT signaling pathway.
Shi WJ, Liu H, Ge YF, Wu D, Tan YJ, Shen YC, Wang H, Xu H
Cytokine 2020 Dec;136:155286
Cytokine 2020 Dec;136:155286
Gu-Ben-Fang-Xiao attenuates allergic airway inflammation by inhibiting BAFF-mediated B cell activation.
Liang ZQ, Tu PC, Ji JJ, Xing QQ, Zhao X
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Dec;132:110801
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Dec;132:110801
Down-regulation of long noncoding RNA LINC00472 alleviates sepsis-induced acute hepatic injury by regulating miR-373-3p/TRIM8 axis.
Li L, He Y, He XJ, Bi MR, Qi YH, Zhu WW
Experimental and molecular pathology 2020 Dec;117:104562
Experimental and molecular pathology 2020 Dec;117:104562
Enterovirus 71 induces neural cell apoptosis and autophagy through promoting ACOX1 downregulation and ROS generation.
You L, Chen J, Liu W, Xiang Q, Luo Z, Wang W, Xu W, Wu K, Zhang Q, Liu Y, Wu J
Virulence 2020 Dec;11(1):537-553
Virulence 2020 Dec;11(1):537-553
Down-regulation of lncRNA DNAJC3-AS1 inhibits colon cancer via regulating miR-214-3p/LIVIN axis.
Han B, Ge Y, Cui J, Liu B
Bioengineered 2020 Dec;11(1):524-535
Bioengineered 2020 Dec;11(1):524-535
Upregulation of the microRNA rno-miR-146b-5p may be involved in the development of intestinal injury through inhibition of Kruppel-like factor 4 in intestinal sepsis.
Tong L, Tang C, Cai C, Guan X
Bioengineered 2020 Dec;11(1):1334-1349
Bioengineered 2020 Dec;11(1):1334-1349
Cannabinoid receptor subtype influence on neuritogenesis in human SH-SY5Y cells.
Lyons EL, Leone-Kabler S, Kovach AL, Thomas BF, Howlett AC
Molecular and cellular neurosciences 2020 Dec;109:103566
Molecular and cellular neurosciences 2020 Dec;109:103566
Targeted degradation of CD147 proteins in melanoma.
Zhou Z, Long J, Wang Y, Li Y, Zhang X, Tang L, Chang Q, Chen Z, Hu G, Hu S, Li Q, Peng C, Chen X
Bioorganic chemistry 2020 Dec;105:104453
Bioorganic chemistry 2020 Dec;105:104453
Design, synthesis and biological evaluation of novel 1,3,4-thiadiazole derivatives as anti-glioblastoma agents targeting the AKT pathway.
Szeliga M, Karpińska M, Rola R, Niewiadomy A
Bioorganic chemistry 2020 Dec;105:104362
Bioorganic chemistry 2020 Dec;105:104362
Latcripin-7A, derivative of Lentinula edodes C91-3, reduces migration and induces apoptosis, autophagy, and cell cycle arrest at G1 phase in breast cancer cells.
Din SRU, Zhong M, Nisar MA, Saleem MZ, Hussain A, Khinsar KH, Alam S, Ayub G, Kanwal S, Li X, Zhang W, Wang X, Ning A, Cao J, Huang M
Applied microbiology and biotechnology 2020 Dec;104(23):10165-10179
Applied microbiology and biotechnology 2020 Dec;104(23):10165-10179
Structural and Functional Characterization of Host FHL1 Protein Interaction with Hypervariable Domain of Chikungunya Virus nsP3 Protein.
Lukash T, Agback T, Dominguez F, Shiliaev N, Meshram C, Frolova EI, Agback P, Frolov I
Journal of virology 2020 Dec 9;95(1)
Journal of virology 2020 Dec 9;95(1)
β-Elemene enhances radiosensitivity in non-small-cell lung cancer by inhibiting epithelial-mesenchymal transition and cancer stem cell traits via Prx-1/NF-kB/iNOS signaling pathway.
Zou K, Li Z, Zhang Y, Mu L, Chen M, Wang R, Deng W, Zou L, Liu J
Aging 2020 Dec 9;13(2):2575-2592
Aging 2020 Dec 9;13(2):2575-2592
Drug-repositioning screening identified fludarabine and risedronic acid as potential therapeutic compounds for malignant pleural mesothelioma.
Dell'Anno I, Martin SA, Barbarino M, Melani A, Silvestri R, Bottaro M, Paolicchi E, Corrado A, Cipollini M, Melaiu O, Giordano A, Luzzi L, Gemignani F, Landi S
Investigational new drugs 2020 Dec 9;
Investigational new drugs 2020 Dec 9;
FN-EDA mediates angiogenesis of hepatic fibrosis via integrin-VEGFR2 in a CD63 synergetic manner.
Su X, Ma X, Xie X, Wu H, Wang L, Feng Y, Yu Z, Liu C, Qi J, Zhu Q
Cell death discovery 2020 Dec 8;6(1):140
Cell death discovery 2020 Dec 8;6(1):140
Dually regulating the proliferation and the immune microenvironment of melanoma via nanoparticle-delivered siRNA targeting onco-immunologic CD155.
Wang Y, Luo YL, Chen YF, Lu ZD, Wang Y, Czarna A, Shen S, Xu CF, Wang J
Biomaterials science 2020 Dec 7;8(23):6683-6694
Biomaterials science 2020 Dec 7;8(23):6683-6694
Extracellular Cystatin F Is Internalised by Cytotoxic T Lymphocytes and Decreases Their Cytotoxicity.
Prunk M, Perišić Nanut M, Jakoš T, Sabotič J, Švajger U, Kos J
Cancers 2020 Dec 6;12(12)
Cancers 2020 Dec 6;12(12)
The protective effect of 1,25(OH)2D3 against cardiac hypertrophy is mediated by the cyclin-dependent kinase inhibitor p21.
Liu N, Su H, Zhang Y, Kong J
European journal of pharmacology 2020 Dec 5;888:173510
European journal of pharmacology 2020 Dec 5;888:173510
YTHDF1 Facilitates the Progression of Hepatocellular Carcinoma by Promoting FZD5 mRNA Translation in an m6A-Dependent Manner.
Liu X, Qin J, Gao T, Li C, He B, Pan B, Xu X, Chen X, Zeng K, Xu M, Zhu C, Pan Y, Sun H, Sun L, Xu T, Wang S
Molecular therapy. Nucleic acids 2020 Dec 4;22:750-765
Molecular therapy. Nucleic acids 2020 Dec 4;22:750-765
circFN1 Mediates Sorafenib Resistance of Hepatocellular Carcinoma Cells by Sponging miR-1205 and Regulating E2F1 Expression.
Yang C, Dong Z, Hong H, Dai B, Song F, Geng L, Lu J, Yang J, Sui C, Xu M
Molecular therapy. Nucleic acids 2020 Dec 4;22:421-433
Molecular therapy. Nucleic acids 2020 Dec 4;22:421-433
Translatome and Transcriptome Profiling of Hypoxic-Induced Rat Cardiomyocytes.
Shen Z, Zeng L, Zhang Z
Molecular therapy. Nucleic acids 2020 Dec 4;22:1016-1024
Molecular therapy. Nucleic acids 2020 Dec 4;22:1016-1024
SPOCK1/SIX1axis promotes breast cancer progression by activating AKT/mTOR signaling.
Xu M, Zhang X, Zhang S, Piao J, Yang Y, Wang X, Lin Z
Aging 2020 Dec 3;13(1):1032-1050
Aging 2020 Dec 3;13(1):1032-1050
Exogenous hydrogen sulfide inhibits apoptosis by regulating endoplasmic reticulum stress-autophagy axis and improves myocardial reconstruction after acute myocardial infarction.
Li Y, Liu M, Yi J, Song X, Zheng X, Liu D, Wang S, Chu C, Yang J
Acta biochimica et biophysica Sinica 2020 Dec 29;52(12):1325-1336
Acta biochimica et biophysica Sinica 2020 Dec 29;52(12):1325-1336
Overexpression of Mucin 1 Suppresses the Therapeutical Efficacy of Disulfiram against Canine Mammary Tumor.
Zhao Y, Lin Z, Lin Z, Zhou C, Liu G, Lin J, Zhang D, Lin D
Animals : an open access journal from MDPI 2020 Dec 27;11(1)
Animals : an open access journal from MDPI 2020 Dec 27;11(1)
Discovery and Biological Evaluation of CD147 N-Glycan Inhibitors: A New Direction in the Treatment of Tumor Metastasis.
Li W, Wang D, Ge Y, Zhang L, Wu J, Liu D
Molecules (Basel, Switzerland) 2020 Dec 23;26(1)
Molecules (Basel, Switzerland) 2020 Dec 23;26(1)
Radiosensitization Effect of AGuIX, a Gadolinium-Based Nanoparticle, in Nonsmall Cell Lung Cancer.
Du Y, Sun H, Lux F, Xie Y, Du L, Xu C, Zhang H, He N, Wang J, Liu Y, Leduc G, Doussineau T, Ji K, Wang Q, Lin Z, Wang Y, Liu Q, Tillement O
ACS applied materials & interfaces 2020 Dec 23;12(51):56874-56885
ACS applied materials & interfaces 2020 Dec 23;12(51):56874-56885
Lanthanum chloride causes blood-brain barrier disruption through intracellular calcium-mediated RhoA/Rho kinase signaling and myosin light chain kinase.
Wu J, Yang J, Yu M, Sun W, Han Y, Lu X, Jin C, Wu S, Cai Y
Metallomics : integrated biometal science 2020 Dec 23;12(12):2075-2083
Metallomics : integrated biometal science 2020 Dec 23;12(12):2075-2083
Schistosoma mansoni eggs induce Wnt/β-catenin signaling and activate the protooncogene c-Jun in human and hamster colon.
Weglage J, Wolters F, Hehr L, Lichtenberger J, Wulz C, Hempel F, Baier A, Quack T, Köhler K, Longerich T, Schramm G, Irungbam K, Mueller H, von Buelow V, Tschuschner A, Odenthal M, Drebber U, Arousy ME, Ramalho LNZ, Bankov K, Wild P, Pons-Kühnemann J, Tschammer J, Grevelding CG, Roeb E, Roderfeld M
Scientific reports 2020 Dec 23;10(1):22373
Scientific reports 2020 Dec 23;10(1):22373
CircPlekha7 plays an anti-fibrotic role in intrauterine adhesions by modulating endometrial stromal cell proliferation and apoptosis.
Xie W, He M, Liu Y, Huang X, Song D, Xiao Y
The Journal of reproduction and development 2020 Dec 22;66(6):493-504
The Journal of reproduction and development 2020 Dec 22;66(6):493-504
Rapalink-1 Targets Glioblastoma Stem Cells and Acts Synergistically with Tumor Treating Fields to Reduce Resistance against Temozolomide.
Vargas-Toscano A, Nickel AC, Li G, Kamp MA, Muhammad S, Leprivier G, Fritsche E, Barker RA, Sabel M, Steiger HJ, Zhang W, Hänggi D, Kahlert UD
Cancers 2020 Dec 21;12(12)
Cancers 2020 Dec 21;12(12)
MELK is an oncogenic kinase essential for metastasis, mitotic progression, and programmed death in lung carcinoma.
Tang Q, Li W, Zheng X, Ren L, Liu J, Li S, Wang J, Du G
Signal transduction and targeted therapy 2020 Dec 2;5(1):279
Signal transduction and targeted therapy 2020 Dec 2;5(1):279
LncRNA LINC00998 inhibits the malignant glioma phenotype via the CBX3-mediated c-Met/Akt/mTOR axis.
Cai H, Yu Y, Ni X, Li C, Hu Y, Wang J, Chen F, Xi S, Chen Z
Cell death & disease 2020 Dec 2;11(12):1032
Cell death & disease 2020 Dec 2;11(12):1032
Variants in RABL2A causing male infertility and ciliopathy.
Ding X, Fragoza R, Singh P, Zhang S, Yu H, Schimenti JC
Human molecular genetics 2020 Dec 18;29(20):3402-3411
Human molecular genetics 2020 Dec 18;29(20):3402-3411
Aldehyde dehydrogenase 2 protects against sympathetic excitation-induced cardiac fibrosis.
Yuan Q, Yang F, Dai S, Wang Z, Xu Y, Xu BC, Sun Y, Zheng B, Zhao Y, Wang W, Liu B, Wang J, Cui S, Cao S, Zhang R, Xue L, Wei S, Xue M, Xu T, Xu F, Chen Y
Biochemical and biophysical research communications 2020 Dec 17;533(4):1427-1434
Biochemical and biophysical research communications 2020 Dec 17;533(4):1427-1434
Pharmacological activation of the p53 pathway by a new compound CYZ2017 exerts anti-tumor effects.
Han Y, Ren Z, Wu Y, Chen Y, Cui Z, Zhu T, Ma M, Du Y, Dong S
Biochemical and biophysical research communications 2020 Dec 17;533(4):1069-1075
Biochemical and biophysical research communications 2020 Dec 17;533(4):1069-1075
The deubiquitinase USP36 Regulates DNA replication stress and confers therapeutic resistance through PrimPol stabilization.
Yan Y, Xu Z, Huang J, Guo G, Gao M, Kim W, Zeng X, Kloeber JA, Zhu Q, Zhao F, Luo K, Lou Z
Nucleic acids research 2020 Dec 16;48(22):12711-12726
Nucleic acids research 2020 Dec 16;48(22):12711-12726
S119N Mutation of the E3 Ubiquitin Ligase SPOP Suppresses SLC7A1 Degradation to Regulate Hepatoblastoma Progression.
He W, Zhang J, Liu B, Liu X, Liu G, Xie L, He J, Wei M, Li K, Ma J, Dong R, Ma D, Dong K, Ye M
Molecular therapy oncolytics 2020 Dec 16;19:149-162
Molecular therapy oncolytics 2020 Dec 16;19:149-162
A novel function of African Swine Fever Virus pE66L in inhibition of host translation by the PKR/eIF2α pathway.
Shen Z, Chen C, Yang Y, Xie Z, Ao Q, Lv L, Zhang S, Chen H, Hu R, Chen H, Peng G
Journal of virology 2020 Dec 16;
Journal of virology 2020 Dec 16;
Exosome-mediated Hic-5 regulates proliferation and apoptosis of osteosarcoma via Wnt/β-catenin signal pathway.
Sha L, Ma D, Chen C
Aging 2020 Dec 13;12(23):23598-23608
Aging 2020 Dec 13;12(23):23598-23608
Hugan Qingzhi medication ameliorates free fatty acid-induced L02 hepatocyte endoplasmic reticulum stress by regulating the activation of PKC-δ.
Yang M, Chen Z, Xiang S, Xia F, Tang W, Yao X, Zhou B
BMC complementary medicine and therapies 2020 Dec 11;20(1):377
BMC complementary medicine and therapies 2020 Dec 11;20(1):377
Epigenetic Inactivation of α-Internexin Accelerates Microtubule Polymerization in Colorectal Cancer.
Li Y, Bai L, Yu H, Cai D, Wang X, Huang B, Peng S, Huang M, Cao G, Kaz AM, Grady WM, Wang J, Luo Y
Cancer research 2020 Dec 1;80(23):5203-5215
Cancer research 2020 Dec 1;80(23):5203-5215
Microtubule poleward flux in human cells is driven by the coordinated action of four kinesins.
Steblyanko Y, Rajendraprasad G, Osswald M, Eibes S, Jacome A, Geley S, Pereira AJ, Maiato H, Barisic M
The EMBO journal 2020 Dec 1;39(23):e105432
The EMBO journal 2020 Dec 1;39(23):e105432
FGF signaling regulates development by processes beyond canonical pathways.
Ray AT, Mazot P, Brewer JR, Catela C, Dinsmore CJ, Soriano P
Genes & development 2020 Dec 1;34(23-24):1735-1752
Genes & development 2020 Dec 1;34(23-24):1735-1752
Silencing of the lncRNA TUG1 attenuates the epithelial-mesenchymal transition of renal tubular epithelial cells by sponging miR-141-3p via regulating β-catenin.
Zhang B, Zhao C, Hou L, Wu Y
American journal of physiology. Renal physiology 2020 Dec 1;319(6):F1125-F1134
American journal of physiology. Renal physiology 2020 Dec 1;319(6):F1125-F1134
iTRAQ-based proteomics implies inflammasome pathway activation in the prefrontal cortex of CSDS mice may influence resilience and susceptibility.
Lan T, Bai M, Chen X, Wang Y, Li Y, Tian Y, He Y, Wu Z, Yu H, Chen Z, Chen C, Yu Y, Cheng K, Xie P
Life sciences 2020 Dec 1;262:118501
Life sciences 2020 Dec 1;262:118501
LncRNA Gm16410 regulates PM2.5-induced lung Endothelial-Mesenchymal Transition via the TGF-β1/Smad3/p-Smad3 pathway.
Ma K, Li C, Xu J, Ren F, Xu X, Liu C, Niu B, Li F
Ecotoxicology and environmental safety 2020 Dec 1;205:111327
Ecotoxicology and environmental safety 2020 Dec 1;205:111327
Inhibition of autophagy enhances cadmium-induced apoptosis in duck renal tubular epithelial cells.
Wang C, Nie G, Zhuang Y, Hu R, Wu H, Xing C, Li G, Hu G, Yang F, Zhang C
Ecotoxicology and environmental safety 2020 Dec 1;205:111188
Ecotoxicology and environmental safety 2020 Dec 1;205:111188
Cadmium inhibits apoptosis of human esophageal epithelial cells by upregulating CDK6.
Yang J, Guo T, Liang X, Zhai Y, Cheng Y, Sun H, Cui Y, Cheng X
Ecotoxicology and environmental safety 2020 Dec 1;205:111146
Ecotoxicology and environmental safety 2020 Dec 1;205:111146
E3 ligase FBXW7 restricts M2-like tumor-associated macrophage polarization by targeting c-Myc.
Zhong L, Zhang Y, Li M, Song Y, Liu D, Yang X, Yang D, Qu H, Lai L, Wang Q, Chen Z
Aging 2020 Dec 1;12(23):24394-24423
Aging 2020 Dec 1;12(23):24394-24423
Cigarette smoke extract induces airway epithelial cell death via repressing PRMT6/AKT signaling.
Li T, Fanning KV, Nyunoya T, Chen Y, Zou C
Aging 2020 Dec 1;12(23):24301-24317
Aging 2020 Dec 1;12(23):24301-24317
Stachydrine ameliorates the progression of intervertebral disc degeneration via the PI3K/Akt/NF-κB signaling pathway: in vitro and in vivo studies.
Shao Z, Lu J, Zhang C, Zeng G, Chen B, Liang H, Wu A, Zhang X, Wang X
Food & function 2020 Dec 1;11(12):10864-10875
Food & function 2020 Dec 1;11(12):10864-10875
The induction and characterization of monoclonal antibodies specific to GP of Ebola virus.
Tian X, Chen D, Wang H, Xu S, Zhu L, Wu X, Wu Z
Journal of medical virology 2020 Aug;92(8):996-1006
Journal of medical virology 2020 Aug;92(8):996-1006
The vulnerability of motor and frontal cortex-dependent behaviors in mice expressing ALS-linked mutation in TDP-43.
Wong P, Ho WY, Yen YC, Sanford E, Ling SC
Neurobiology of aging 2020 Aug;92:43-60
Neurobiology of aging 2020 Aug;92:43-60
Differential Effects of Components in Artemisia annua Extract on the Induction of Drug-Metabolizing Enzyme Expression Mediated by Nuclear Receptors.
Zhang X, Meng R, Wang H, Xing J
Planta medica 2020 Aug;86(12):867-875
Planta medica 2020 Aug;86(12):867-875
Rhein attenuates renal inflammatory injury of uric acid nephropathy via lincRNA-Cox2/miR-150-5p/STAT1 axis.
Hu J, Yang Z, Wu H, Wang D
International immunopharmacology 2020 Aug;85:106620
International immunopharmacology 2020 Aug;85:106620
Melatonin alleviates intestinal injury, neuroinflammation and cognitive dysfunction caused by intestinal ischemia/reperfusion.
Yang B, Zhang LY, Chen Y, Bai YP, Jia J, Feng JG, Liu KX, Zhou J
International immunopharmacology 2020 Aug;85:106596
International immunopharmacology 2020 Aug;85:106596
IL-38 alleviates the inflammatory response and the degeneration of nucleus pulposus cells via inhibition of the NF-κB signaling pathway in vitro.
Yu H, Liu Y, Xie W, Xie Q, Liu Q, Cheng L
International immunopharmacology 2020 Aug;85:106592
International immunopharmacology 2020 Aug;85:106592
To what extent should the intestinal be resected proximally after radiotherapy: hint from a pathological view.
Wu PH, Zhong QH, Ma TH, Qin QY, Huang XY, Kuang YY, Wang HM, Yuan ZX, Wang L, Chen DC
Gastroenterology report 2020 Aug;8(4):277-285
Gastroenterology report 2020 Aug;8(4):277-285
Rationalized inhibition of mixed lineage kinase 3 and CD70 enhances life span and antitumor efficacy of CD8+ T cells.
Kumar S, Singh SK, Viswakarma N, Sondarva G, Nair RS, Sethupathi P, Dorman M, Sinha SC, Hoskins K, Thatcher G, Rana B, Rana A
Journal for immunotherapy of cancer 2020 Aug;8(2)
Journal for immunotherapy of cancer 2020 Aug;8(2)
The role of miR-34c-5p/Notch in epithelial-mesenchymal transition (EMT) in endometriosis.
Luo Y, Wang D, Chen S, Yang Q
Cellular signalling 2020 Aug;72:109666
Cellular signalling 2020 Aug;72:109666
miR-296-5p suppresses stem cell potency of hepatocellular carcinoma cells via regulating Brg1/Sall4 axis.
Shi DM, Shi XL, Xing KL, Zhou HX, Lu LL, Wu WZ
Cellular signalling 2020 Aug;72:109650
Cellular signalling 2020 Aug;72:109650
m6A mRNA Methylation Controls Functional Maturation in Neonatal Murine β-Cells.
Wang Y, Sun J, Lin Z, Zhang W, Wang S, Wang W, Wang Q, Ning G
Diabetes 2020 Aug;69(8):1708-1722
Diabetes 2020 Aug;69(8):1708-1722
Metabolomic profiling reveals similar cytotoxic effects and protective functions of quercetin during deoxynivalenol- and 15-acetyl deoxynivalenol-induced cell apoptosis.
Yang YX, Yu S, Jia BX, Liu N, Wu A
Toxicology in vitro : an international journal published in association with BIBRA 2020 Aug;66:104838
Toxicology in vitro : an international journal published in association with BIBRA 2020 Aug;66:104838
miR-410-5p promotes the development of diabetic cardiomyopathy by suppressing PIM1-induced anti-apoptosis.
Xia X, Liang Y, Zheng W, Lin D, Sun S
Molecular and cellular probes 2020 Aug;52:101558
Molecular and cellular probes 2020 Aug;52:101558
Exosomes derived from human exfoliated deciduous teeth ameliorate adult bone loss in mice through promoting osteogenesis.
Wei J, Song Y, Du Z, Yu F, Zhang Y, Jiang N, Ge X
Journal of molecular histology 2020 Aug;51(4):455-466
Journal of molecular histology 2020 Aug;51(4):455-466
The AKR1B1 inhibitor epalrestat suppresses the progression of cervical cancer.
Ji J, Xu MX, Qian TY, Zhu SZ, Jiang F, Liu ZX, Xu WS, Zhou J, Xiao MB
Molecular biology reports 2020 Aug;47(8):6091-6103
Molecular biology reports 2020 Aug;47(8):6091-6103
Neferine Inhibits Expression of Inflammatory Mediators and Matrix Degrading Enzymes in IL-1β-Treated Rat Chondrocytes via Suppressing MAPK and NF-κB Signaling Pathways.
Ni B, Huang X, Xi Y, Mao Z, Chu X, Zhang R, Ma X, You H
Inflammation 2020 Aug;43(4):1209-1221
Inflammation 2020 Aug;43(4):1209-1221
Schisandrin B improves cerebral ischemia and reduces reperfusion injury in rats through TLR4/NF-κB signaling pathway inhibition.
Fan X, Elkin K, Shi Y, Zhang Z, Cheng Y, Gu J, Liang J, Wang C, Ji X
Neurological research 2020 Aug;42(8):693-702
Neurological research 2020 Aug;42(8):693-702
Rare mutations in the autophagy-regulating gene AMBRA1 contribute to human neural tube defects.
Ye J, Tong Y, Lv J, Peng R, Chen S, Kuang L, Su K, Zheng Y, Zhang T, Zhang F, Jin L, Yang X, Wang H
Human mutation 2020 Aug;41(8):1383-1393
Human mutation 2020 Aug;41(8):1383-1393
Red nucleus IL-6 mediates the maintenance of neuropathic pain by inducing the productions of TNF-α and IL-1β through the JAK2/STAT3 and ERK signaling pathways.
Yang QQ, Li HN, Zhang ST, Yu YL, Wei W, Zhang X, Wang JY, Zeng XY
Neuropathology : official journal of the Japanese Society of Neuropathology 2020 Aug;40(4):347-357
Neuropathology : official journal of the Japanese Society of Neuropathology 2020 Aug;40(4):347-357
Astragaloside IV attenuates chronic intermittent hypoxia-induced myocardial injury by modulating Ca2+ homeostasis.
Jiang S, Jiao G, Chen Y, Han M, Wang X, Liu W
Cell biochemistry and function 2020 Aug;38(6):710-720
Cell biochemistry and function 2020 Aug;38(6):710-720
MiR-129-5p alleviates myocardial injury by targeting suppressor of cytokine signaling 2 after ischemia/reperfusion.
Ma R, Chen X, Ma Y, Bai G, Li DS
The Kaohsiung journal of medical sciences 2020 Aug;36(8):599-606
The Kaohsiung journal of medical sciences 2020 Aug;36(8):599-606
Effect of AmyTrap, an amyloid-β binding drug, on Aβ induced mitochondrial dysfunction and tau phosphorylation in cultured neuroblastoma cells.
Gandbhir O, Sundaram P
Metabolic brain disease 2020 Aug;35(6):923-931
Metabolic brain disease 2020 Aug;35(6):923-931
Curcumin inhibits calcification of human aortic valve interstitial cells by interfering NF-κB, AKT, and ERK pathways.
Zhou T, Wang Y, Liu M, Huang Y, Shi J, Dong N, Xu K
Phytotherapy research : PTR 2020 Aug;34(8):2074-2081
Phytotherapy research : PTR 2020 Aug;34(8):2074-2081
Src-mediated phosphorylation of GAPDH regulates its nuclear localization and cellular response to DNA damage.
Ci S, Xia W, Liang W, Qin L, Zhang Y, Dianov GL, Wang M, Zhao X, Wu C, Alagamuthu KK, Hu Z, He L, Pan F, Guo Z
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Aug;34(8):10443-10461
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Aug;34(8):10443-10461
Hydrogen sulphide ameliorating skeletal muscle atrophy in db/db mice via Muscle RING finger 1 S-sulfhydration.
Lu F, Lu B, Zhang L, Wen J, Wang M, Zhang S, Li Q, Shu F, Sun Y, Liu N, Peng S, Zhao Y, Dong S, Zhao D, Lu F, Zhang W
Journal of cellular and molecular medicine 2020 Aug;24(16):9362-9377
Journal of cellular and molecular medicine 2020 Aug;24(16):9362-9377
Effects of PYRIN-containing Apaf1-like protein 1 on isoflurane-induced postoperative cognitive dysfunction in aged rats.
Zhang X, Fan X, Li F, Qiu J, Zhang Y
Molecular medicine reports 2020 Aug;22(2):1391-1399
Molecular medicine reports 2020 Aug;22(2):1391-1399
Overexpression of negative regulator of ubiquitin-like proteins 1 (NUB1) inhibits proliferation and invasion of gastric cancer cells through upregulation of p27Kip1 and inhibition of epithelial-mesenchymal transition.
Zhang D, Wu P, Zhang Z, An W, Zhang C, Pan S, Tan Y, Xu H
Pathology, research and practice 2020 Aug;216(8):153002
Pathology, research and practice 2020 Aug;216(8):153002
Cloning of the XPD gene and its function in malignant melanoma cells.
Wang Y, Zhou Y, Wang Y, Peng C, Gao M
Oncology letters 2020 Aug;20(2):1803-1809
Oncology letters 2020 Aug;20(2):1803-1809
miR-140-3p enhances cisplatin sensitivity and attenuates stem cell-like properties through repressing Wnt/β-catenin signaling in lung adenocarcinoma cells.
Wu S, Wang H, Pan Y, Yang X, Wu D
Experimental and therapeutic medicine 2020 Aug;20(2):1664-1674
Experimental and therapeutic medicine 2020 Aug;20(2):1664-1674
ZMIZ1 promotes the proliferation and migration of melanocytes in vitiligo.
Li M, Fan Y, Wang Y, Xu J, Xu H
Experimental and therapeutic medicine 2020 Aug;20(2):1371-1378
Experimental and therapeutic medicine 2020 Aug;20(2):1371-1378
BX795 demonstrates potent antiviral benefits against herpes simplex Virus-1 infection of human cell lines.
Iqbal A, Suryawanshi R, Yadavalli T, Volety I, Shukla D
Antiviral research 2020 Aug;180:104814
Antiviral research 2020 Aug;180:104814
miR-106a Regulates Cell Proliferation and Autophagy by Targeting LKB1 in HPV-16-Associated Cervical Cancer.
Cui X, Wang X, Zhou X, Jia J, Chen H, Zhao W
Molecular cancer research : MCR 2020 Aug;18(8):1129-1141
Molecular cancer research : MCR 2020 Aug;18(8):1129-1141
Targeting G6PD reverses paclitaxel resistance in ovarian cancer by suppressing GSTP1.
Feng Q, Li X, Sun W, Sun M, Li Z, Sheng H, Xie F, Zhang S, Shan C
Biochemical pharmacology 2020 Aug;178:114092
Biochemical pharmacology 2020 Aug;178:114092
Celastrol ameliorates autoimmune disorders in Trex1-deficient mice.
Liu Y, Xiao N, Du H, Kou M, Lin L, Huang M, Zhang S, Xu S, Li D, Chen Q
Biochemical pharmacology 2020 Aug;178:114090
Biochemical pharmacology 2020 Aug;178:114090
Hippocampal glutamatergic synapses impairment mediated novel-object recognition dysfunction in rats with neuropathic pain.
Xiong B, Zhang W, Zhang L, Huang X, Zhou W, Zou Q, Manyande A, Wang J, Tian Y, Tian X
Pain 2020 Aug;161(8):1824-1836
Pain 2020 Aug;161(8):1824-1836
Correcting abnormalities in miR-124/PTPN1 signaling rescues tau pathology in Alzheimer's disease.
Hou TY, Zhou Y, Zhu LS, Wang X, Pang P, Wang DQ, Liuyang ZY, Man H, Lu Y, Zhu LQ, Liu D
Journal of neurochemistry 2020 Aug;154(4):441-457
Journal of neurochemistry 2020 Aug;154(4):441-457
Overexpression of PTEN regulated by miR-19b and miR-494 in the villous of recurrent spontaneous abortion patients.
Tian S, Yu J, Zhang Y, Bian Y, Ma J, Yan J
Journal of reproductive immunology 2020 Aug;140:103133
Journal of reproductive immunology 2020 Aug;140:103133
Apocynum venetum leaf extract protects against H2O2-induced oxidative stress by increasing autophagy in PC12 cells.
Feng Y, Jiang C, Yang F, Chen Z, Li Z
Biomedical reports 2020 Aug;13(2):6
Biomedical reports 2020 Aug;13(2):6
Prunella vulgaris L. attenuates experimental autoimmune thyroiditis by inducing indoleamine 2,3-dioxygenase 1 expression and regulatory T cell expansion.
Qiu H, Zhang J, Guo Q, Zhang Y, Zhong X
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Aug;128:110288
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Aug;128:110288
Glibenclamide restores dopaminergic reward circuitry in obese mice through interscauplar brown adipose tissue.
Kuo YY, Lin JK, Lin YT, Chen JC, Kuo YM, Chen PS, Wu SN, Chen PC
Psychoneuroendocrinology 2020 Aug;118:104712
Psychoneuroendocrinology 2020 Aug;118:104712
MiR-195 suppression alleviates apoptosis and oxidative stress in CCl4-induced ALI in mice by targeting Pim-1.
Yang K, Zou Z, Wu Y, Hu G
Experimental and molecular pathology 2020 Aug;115:104438
Experimental and molecular pathology 2020 Aug;115:104438
Sarcopenia is attenuated by TRB3 knockout in aging mice via the alleviation of atrophy and fibrosis of skeletal muscles.
Shang GK, Han L, Wang ZH, Liu YP, Yan SB, Sai WW, Wang D, Li YH, Zhang W, Zhong M
Journal of cachexia, sarcopenia and muscle 2020 Aug;11(4):1104-1120
Journal of cachexia, sarcopenia and muscle 2020 Aug;11(4):1104-1120
The mechanism of Chinese herbal formula HQT in the treatment of rheumatoid arthritis is related to its regulation of lncRNA uc.477 and miR-19b.
Wang M, Mei L, Liu Z, Tang X, Wu X, Chen X, Zhao Y, Huang Q, Huang R
Journal of leukocyte biology 2020 Aug;108(2):519-529
Journal of leukocyte biology 2020 Aug;108(2):519-529
MiR-221/222 promote migration and invasion, and inhibit autophagy and apoptosis by modulating ATG10 in aggressive papillary thyroid carcinoma.
Shen H, Lin Z, Shi H, Wu L, Ma B, Li H, Yin B, Tang J, Yu H, Yin X
3 Biotech 2020 Aug;10(8):339
3 Biotech 2020 Aug;10(8):339
METTL3 and N6-Methyladenosine Promote Homologous Recombination-Mediated Repair of DSBs by Modulating DNA-RNA Hybrid Accumulation.
Zhang C, Chen L, Peng D, Jiang A, He Y, Zeng Y, Xie C, Zhou H, Luo X, Liu H, Chen L, Ren J, Wang W, Zhao Y
Molecular cell 2020 Aug 6;79(3):425-442.e7
Molecular cell 2020 Aug 6;79(3):425-442.e7
Partial MHC/neuroantigen peptide constructs attenuate methamphetamine-seeking and brain chemokine (C-C motif) ligand 2 levels in rats.
Loftis JM, Navis T, Taylor J, Hudson R, Person U, Lattal KM, Vandenbark AA, Shirley R, Huckans M
European journal of pharmacology 2020 Aug 5;880:173175
European journal of pharmacology 2020 Aug 5;880:173175
Schisandrin ameliorates cognitive deficits, endoplasmic reticulum stress and neuroinflammation in streptozotocin (STZ)-induced Alzheimer's disease rats.
Song L, Piao Z, Yao L, Zhang L, Lu Y
Experimental animals 2020 Aug 5;69(3):363-373
Experimental animals 2020 Aug 5;69(3):363-373
Butyrate-mediated autophagy inhibition limits cytosolic Salmonella Infantis replication in the colon of pigs treated with a mixture of Lactobacillus and Bacillus.
Chu B, Zhu Y, Su J, Xia B, Zou Y, Nie J, Zhang W, Wang J
Veterinary research 2020 Aug 5;51(1):99
Veterinary research 2020 Aug 5;51(1):99
Neutrophil extracellular traps amplify neutrophil recruitment and inflammation in neutrophilic asthma by stimulating the airway epithelial cells to activate the TLR4/ NF-κB pathway and secrete chemokines.
Wan R, Jiang J, Hu C, Chen X, Chen C, Zhao B, Hu X, Zheng Z, Li Y
Aging 2020 Aug 5;12(17):16820-16836
Aging 2020 Aug 5;12(17):16820-16836
DNA methylation of Hugl-2 is a prognostic biomarker in kidney renal clear cell carcinoma.
Miao Y, Cao F, Li P, Liu P
Clinical and experimental pharmacology & physiology 2020 Aug 5;
Clinical and experimental pharmacology & physiology 2020 Aug 5;
Icotinib Attenuates Monocrotaline-Induced Pulmonary Hypertension by Preventing Pulmonary Arterial Smooth Muscle Cell Dysfunction.
Peng LY, Yu M, Yang MX, Liu P, Zhou H, Huang W, Kong H, Xie WP
American journal of hypertension 2020 Aug 4;33(8):775-783
American journal of hypertension 2020 Aug 4;33(8):775-783
Macrophage K63-Linked Ubiquitination of YAP Promotes Its Nuclear Localization and Exacerbates Atherosclerosis.
Liu M, Yan M, Lv H, Wang B, Lv X, Zhang H, Xiang S, Du J, Liu T, Tian Y, Zhang X, Zhou F, Cheng T, Zhu Y, Jiang H, Cao Y, Ai D
Cell reports 2020 Aug 4;32(5):107990
Cell reports 2020 Aug 4;32(5):107990
Nicotinamide Mononucleotide Supplementation Reverses the Declining Quality of Maternally Aged Oocytes.
Miao Y, Cui Z, Gao Q, Rui R, Xiong B
Cell reports 2020 Aug 4;32(5):107987
Cell reports 2020 Aug 4;32(5):107987
miR-4634 augments the anti-tumor effects of RAD001 and associates well with clinical prognosis of non-small cell lung cancer.
Liu S, Zang H, Zheng H, Wang W, Wen Q, Zhan Y, Yang Y, Ning Y, Wang H, Fan S
Scientific reports 2020 Aug 4;10(1):13079
Scientific reports 2020 Aug 4;10(1):13079
An Optimized Reverse Genetics System Suitable for Efficient Recovery of Simian, Human, and Murine-Like Rotaviruses.
Sánchez-Tacuba L, Feng N, Meade NJ, Mellits KH, Jaïs PH, Yasukawa LL, Resch TK, Jiang B, López S, Ding S, Greenberg HB
Journal of virology 2020 Aug 31;94(18)
Journal of virology 2020 Aug 31;94(18)
16-Hydroxycleroda-3,13-dien-15,16-olide Induces Apoptosis in Human Bladder Cancer Cells through Cell Cycle Arrest, Mitochondria ROS Overproduction, and Inactivation of EGFR-Related Signalling Pathways.
Chen YC, Wang PY, Huang BM, Chen YJ, Lee WC, Chen YC
Molecules (Basel, Switzerland) 2020 Aug 30;25(17)
Molecules (Basel, Switzerland) 2020 Aug 30;25(17)
Promising xenograft animal model recapitulating the features of human pancreatic cancer.
Miao JX, Wang JY, Li HZ, Guo HR, Dunmall LSC, Zhang ZX, Cheng ZG, Gao DL, Dong JZ, Wang ZD, Wang YH
World journal of gastroenterology 2020 Aug 28;26(32):4802-4816
World journal of gastroenterology 2020 Aug 28;26(32):4802-4816
LncRNA SNHG16 promotes colorectal cancer cell proliferation, migration, and epithelial-mesenchymal transition through miR-124-3p/MCP-1.
Chen ZY, Wang XY, Yang YM, Wu MH, Yang L, Jiang DT, Cai H, Peng Y
Gene therapy 2020 Aug 28;
Gene therapy 2020 Aug 28;
The HMGB1-2 Ovarian Cancer Interactome. The Role of HMGB Proteins and Their Interacting Partners MIEN1 and NOP53 in Ovary Cancer and Drug-Response.
Cámara-Quílez M, Barreiro-Alonso A, Vizoso-Vázquez Á, Rodríguez-Belmonte E, Quindós-Varela M, Lamas-Maceiras M, Cerdán ME
Cancers 2020 Aug 27;12(9)
Cancers 2020 Aug 27;12(9)
Chidamide, a histone deacetylase inhibitor, inhibits autophagy and exhibits therapeutic implication in chronic lymphocytic leukemia.
Kong YL, Pan BH, Liang JH, Zhu HY, Wang L, Xia Y, Wu JZ, Fan L, Li JY, Xu W
Aging 2020 Aug 27;12(16):16083-16098
Aging 2020 Aug 27;12(16):16083-16098
The Circadian Hormone Melatonin Inhibits Morphine-Induced Tolerance and Inflammation via the Activation of Antioxidative Enzymes.
Chen IJ, Yang CP, Lin SH, Lai CM, Wong CS
Antioxidants (Basel, Switzerland) 2020 Aug 22;9(9)
Antioxidants (Basel, Switzerland) 2020 Aug 22;9(9)
Small molecules targeting RORγt inhibit autoimmune disease by suppressing Th17 cell differentiation.
Tan J, Liu H, Huang M, Li N, Tang S, Meng J, Tang S, Zhou H, Kijlstra A, Yang P, Hou S
Cell death & disease 2020 Aug 22;11(8):697
Cell death & disease 2020 Aug 22;11(8):697
The gut microbiota regulates autism-like behavior by mediating vitamin B6 homeostasis in EphB6-deficient mice.
Li Y, Luo ZY, Hu YY, Bi YW, Yang JM, Zou WJ, Song YL, Li S, Shen T, Li SJ, Huang L, Zhou AJ, Gao TM, Li JM
Microbiome 2020 Aug 20;8(1):120
Microbiome 2020 Aug 20;8(1):120
In Vitro and In Vivo Activity, Tolerability, and Mechanism of Action of BX795 as an Antiviral against Herpes Simplex Virus 2 Genital Infection.
Hopkins J, Yadavalli T, Suryawanshi R, Qatanani F, Volety I, Koganti R, Iqbal A, Shukla D
Antimicrobial agents and chemotherapy 2020 Aug 20;64(9)
Antimicrobial agents and chemotherapy 2020 Aug 20;64(9)
A kinase-independent function for AURORA-A in replisome assembly during DNA replication initiation.
Guarino Almeida E, Renaudin X, Venkitaraman AR
Nucleic acids research 2020 Aug 20;48(14):7844-7855
Nucleic acids research 2020 Aug 20;48(14):7844-7855
A CRISPR knockout negative screen reveals synergy between CDKs inhibitor and metformin in the treatment of human cancer in vitro and in vivo.
Ma Y, Zhu Q, Liang J, Li Y, Li M, Zhang Y, Wang X, Zeng Y, Jiao Y
Signal transduction and targeted therapy 2020 Aug 19;5(1):152
Signal transduction and targeted therapy 2020 Aug 19;5(1):152
Exosomal Delivery of AntagomiRs Targeting Viral and Cellular MicroRNAs Synergistically Inhibits Cancer Angiogenesis.
Wang J, Jiang Q, Faleti OD, Tsang CM, Zhao M, Wu G, Tsao SW, Fu M, Chen Y, Ding T, Chong T, Long Y, Yang X, Zhang Y, Cai Y, Li H, Peng M, Lyu X, Li X
Molecular therapy. Nucleic acids 2020 Aug 19;22:153-165
Molecular therapy. Nucleic acids 2020 Aug 19;22:153-165
Antidepressant-like Effect of Merazin Hydrate Depends on NO/ERK by Suppressing Its Downstream NF-κB or Nonactivating CREB/BDNF in Mouse Hippocampus.
Wu L, Liu X, Huang Y, Lu C, Zhou J, Ren P, Huang X
ACS chemical neuroscience 2020 Aug 19;11(16):2472-2481
ACS chemical neuroscience 2020 Aug 19;11(16):2472-2481
Ubiquitin-Conjugating Enzyme 2S Enhances Viral Replication by Inhibiting Type I IFN Production through Recruiting USP15 to Deubiquitinate TBK1.
Huang L, Liu H, Zhang K, Meng Q, Hu L, Zhang Y, Xiang Z, Li J, Yang Y, Chen Y, Cui S, Tang H, Pei H, Bu Z, Weng C
Cell reports 2020 Aug 18;32(7):108044
Cell reports 2020 Aug 18;32(7):108044
Novel dot-blot assay for detection of vascular Notch3 aggregates in patients with CADASIL.
Ma Y, Ueda M, Ueda A, Shinriki S, Nagatoshi A, Isoguchi A, Okada M, Tasaki M, Nomura T, Inoue Y, Masuda T, Misumi Y, Yamashita T, Matsui H, Ando Y
Journal of the neurological sciences 2020 Aug 15;415:116931
Journal of the neurological sciences 2020 Aug 15;415:116931
Lamin B2 promotes the malignant phenotype of non-small cell lung cancer cells by upregulating dimethylation of histone 3 lysine 9.
Zhang MY, Han YC, Han Q, Liang Y, Luo Y, Wei L, Yan T, Yang Y, Liu SL, Wang EH
Experimental cell research 2020 Aug 15;393(2):112090
Experimental cell research 2020 Aug 15;393(2):112090
Lactobacillus johnsonii L531 Ameliorates Escherichia coli-Induced Cell Damage via Inhibiting NLRP3 Inflammasome Activity and Promoting ATG5/ATG16L1-Mediated Autophagy in Porcine Mammary Epithelial Cells.
Zou YJ, Xu JJ, Wang X, Zhu YH, Wu Q, Wang JF
Veterinary sciences 2020 Aug 14;7(3)
Veterinary sciences 2020 Aug 14;7(3)
Magnetic targeting enhances the cutaneous wound healing effects of human mesenchymal stem cell-derived iron oxide exosomes.
Li X, Wang Y, Shi L, Li B, Li J, Wei Z, Lv H, Wu L, Zhang H, Yang B, Xu X, Jiang J
Journal of nanobiotechnology 2020 Aug 14;18(1):113
Journal of nanobiotechnology 2020 Aug 14;18(1):113
TRIM59 attenuates IL-1β-driven cartilage matrix degradation in osteoarthritis via direct suppression of NF-κB and JAK2/STAT3 signaling pathway.
Teng Y, Ni G, Zhang W, Hua J, Sun L, Zheng M, Dong Q, Huang W
Biochemical and biophysical research communications 2020 Aug 13;529(1):28-34
Biochemical and biophysical research communications 2020 Aug 13;529(1):28-34
A cell-based high-throughput screen identifies drugs that cause bleeding disorders by off-targeting the vitamin K cycle.
Chen X, Li C, Jin DY, Ingram B, Hao Z, Bai X, Stafford DW, Hu K, Tie JK
Blood 2020 Aug 13;136(7):898-908
Blood 2020 Aug 13;136(7):898-908
Flavagline synthetic derivative induces senescence in glioblastoma cancer cells without being toxic to healthy astrocytes.
Harmouch E, Seitlinger J, Chaddad H, Ubeaud-Sequier G, Barths J, Saidu S, Désaubry L, Grandemange S, Massfelder T, Fuhrmann G, Fioretti F, Dontenwill M, Benkirane-Jessel N, Idoux-Gillet Y
Scientific reports 2020 Aug 13;10(1):13750
Scientific reports 2020 Aug 13;10(1):13750
Acetylation of Cytidine Residues Boosts HIV-1 Gene Expression by Increasing Viral RNA Stability.
Tsai K, Jaguva Vasudevan AA, Martinez Campos C, Emery A, Swanstrom R, Cullen BR
Cell host & microbe 2020 Aug 12;28(2):306-312.e6
Cell host & microbe 2020 Aug 12;28(2):306-312.e6
Amyloid precursor protein glycosylation is altered in the brain of patients with Alzheimer's disease.
Boix CP, Lopez-Font I, Cuchillo-Ibañez I, Sáez-Valero J
Alzheimer's research & therapy 2020 Aug 12;12(1):96
Alzheimer's research & therapy 2020 Aug 12;12(1):96
Expressional Localization and Functionally Identifying an RNA Editing Enzyme BmADARa of the Silkworm Bombyx mori.
Ye C, Jiang S, Gong M, Min Q, Fan M, Gao J, Meng Y
Insects 2020 Aug 12;11(8)
Insects 2020 Aug 12;11(8)
Qingda granule inhibits angiotensin Ⅱ induced VSMCs proliferation through MAPK and PI3K/AKT pathways.
Yu N, Shen A, Chu J, Huang Y, Zhang L, Lin S, Cai Q, Sankararaman S, Sferra TJ, Chen Y, Peng J
Journal of ethnopharmacology 2020 Aug 10;258:112767
Journal of ethnopharmacology 2020 Aug 10;258:112767
Frequent and mild scrotal heat stress in mice epigenetically alters glucose metabolism in the male offspring.
Wan X, He X, Liu Q, Wang X, Ding X, Li H
American journal of physiology. Endocrinology and metabolism 2020 Aug 1;319(2):E291-E304
American journal of physiology. Endocrinology and metabolism 2020 Aug 1;319(2):E291-E304
Dual-specificity phosphatase 29 is induced during neurogenic skeletal muscle atrophy and attenuates glucocorticoid receptor activity in muscle cell culture.
Cooper LM, West RC, Hayes CS, Waddell DS
American journal of physiology. Cell physiology 2020 Aug 1;319(2):C441-C454
American journal of physiology. Cell physiology 2020 Aug 1;319(2):C441-C454
Chlorogenic acid attenuates cyclophosphamide-induced rat interstitial cystitis.
Luo J, Yang C, Luo X, Yang Y, Li J, Song B, Zhao J, Li L
Life sciences 2020 Aug 1;254:117590
Life sciences 2020 Aug 1;254:117590
Syndecan-1 regulates extracellular matrix expression in keloid fibroblasts via TGF-β1/Smad and MAPK signaling pathways.
Cui J, Jin S, Jin C, Jin Z
Life sciences 2020 Aug 1;254:117326
Life sciences 2020 Aug 1;254:117326
Dandelion Extract Alleviated Lipopolysaccharide-Induced Oxidative Stress through the Nrf2 Pathway in Bovine Mammary Epithelial Cells.
Sun Y, Wu Y, Wang Z, Chen J, Yang Y, Dong G
Toxins 2020 Aug 1;12(8)
Toxins 2020 Aug 1;12(8)
MicroRNA-378-3p/5p suppresses the migration and invasiveness of oral squamous carcinoma cells by inhibiting KLK4 expression.
Cui Z, Sun S, Liu Q, Zhou X, Gao S, Peng P, Li Q
Biochemistry and cell biology = Biochimie et biologie cellulaire 2020 Apr;98(2):154-163
Biochemistry and cell biology = Biochimie et biologie cellulaire 2020 Apr;98(2):154-163
Anethole compromises human sperm function by affecting the sperm intracellular calcium concentration and tyrosine phosphorylation.
Luo T, Wang F, Weng S, Chen H, Kang H, Wang J, Luo S
Reproductive toxicology (Elmsford, N.Y.) 2020 Apr;93:99-105
Reproductive toxicology (Elmsford, N.Y.) 2020 Apr;93:99-105
miR-455-3p enhances chondrocytes apoptosis and inflammation by targeting COL2A1 in the in vitro osteoarthritis model.
Cheng F, Hu H, Sun K, Yan F, Geng Y
Bioscience, biotechnology, and biochemistry 2020 Apr;84(4):695-702
Bioscience, biotechnology, and biochemistry 2020 Apr;84(4):695-702
Glaucocalyxin A alleviates LPS-mediated septic shock and inflammation via inhibiting NLRP3 inflammasome activation.
Hou X, Xu G, Wang Z, Zhan X, Li H, Li R, Shi W, Wang C, Chen Y, Ai Y, Xiao X, Bai Z
International immunopharmacology 2020 Apr;81:106271
International immunopharmacology 2020 Apr;81:106271
Baicalin attenuates hepatic injury in non-alcoholic steatohepatitis cell model by suppressing inflammasome-dependent GSDMD-mediated cell pyroptosis.
Shi H, Zhang Y, Xing J, Liu L, Qiao F, Li J, Chen Y
International immunopharmacology 2020 Apr;81:106195
International immunopharmacology 2020 Apr;81:106195
Cellular secretion and cytotoxicity of transthyretin mutant proteins underlie late-onset amyloidosis and neurodegeneration.
Ibrahim RB, Yeh SY, Lin KP, Ricardo F, Yu TY, Chan CC, Tsai JW, Liu YT
Cellular and molecular life sciences : CMLS 2020 Apr;77(7):1421-1434
Cellular and molecular life sciences : CMLS 2020 Apr;77(7):1421-1434
Synergistic effects of tanshinone IIA and andrographolide on the apoptosis of cancer cells via crosstalk between p53 and reactive oxygen species pathways.
Li Y, Jiang B, Wang R, Wang J, Li Y, Bao Y
Pharmacological reports : PR 2020 Apr;72(2):400-417
Pharmacological reports : PR 2020 Apr;72(2):400-417
Streptococcus pneumoniae aminopeptidase N contributes to bacterial virulence and elicits a strong innate immune response through MAPK and PI3K/AKT signaling.
Wang L, Zhang X, Wu G, Qi Y, Zhang J, Yang J, Wang H, Xu W
Journal of microbiology (Seoul, Korea) 2020 Apr;58(4):330-339
Journal of microbiology (Seoul, Korea) 2020 Apr;58(4):330-339
E6‑regulated overproduction of prostaglandin E2 may inhibit migration of dendritic cells in human papillomavirus 16‑positive cervical lesions.
Huang J, Diao G, Zhang Q, Chen Y, Han J, Guo J
International journal of oncology 2020 Apr;56(4):921-931
International journal of oncology 2020 Apr;56(4):921-931
Effects of rutin on the oxidative stress, proliferation and osteogenic differentiation of periodontal ligament stem cells in LPS-induced inflammatory environment and the underlying mechanism.
Zhao B, Zhang W, Xiong Y, Zhang Y, Zhang D, Xu X
Journal of molecular histology 2020 Apr;51(2):161-171
Journal of molecular histology 2020 Apr;51(2):161-171
Long noncoding RNA MACC1-AS1 promotes the stemness of hepatocellular carcinoma cells by antagonizing miR-145.
Guo Y, Zhong J, Wu F, Zhan Z
The Journal of international medical research 2020 Apr;48(4):300060520920411
The Journal of international medical research 2020 Apr;48(4):300060520920411
LncRNA MIAT/miR-133a-3p axis regulates atrial fibrillation and atrial fibrillation-induced myocardial fibrosis.
Yao L, Zhou B, You L, Hu H, Xie R
Molecular biology reports 2020 Apr;47(4):2605-2617
Molecular biology reports 2020 Apr;47(4):2605-2617
Low-intensity pulsed ultrasound promotes the expression of immediate-early genes in mouse ST2 bone marrow stromal cells.
Tabuchi Y, Hasegawa H, Suzuki N, Furusawa Y, Hirano T, Nagaoka R, Takeuchi SI, Shiiba M, Mochizuki T
Journal of medical ultrasonics (2001) 2020 Apr;47(2):193-201
Journal of medical ultrasonics (2001) 2020 Apr;47(2):193-201
Down-regulation of lncRNA BLACAT1 inhibits ovarian cancer progression by suppressing the Wnt/β-catenin signaling pathway via regulating miR-519d-3p.
Yang H, Qi Y, Wang XL, Gu JJ, Shi TM
Molecular and cellular biochemistry 2020 Apr;467(1-2):95-105
Molecular and cellular biochemistry 2020 Apr;467(1-2):95-105
Rab22a is a novel prognostic marker for cell progression in breast cancer.
He M, Shen L, Jiang C, Gao G, Wang K, Jiao Y, Sun L, Cui Y, Ke Z, Yang Z
International journal of molecular medicine 2020 Apr;45(4):1037-1046
International journal of molecular medicine 2020 Apr;45(4):1037-1046
Sirtuin 2 Inhibition Attenuates Sevoflurane-Induced Learning and Memory Deficits in Developing Rats via Modulating Microglial Activation.
Wu Z, Zhang Y, Zhang Y, Zhao P
Cellular and molecular neurobiology 2020 Apr;40(3):437-446
Cellular and molecular neurobiology 2020 Apr;40(3):437-446
CFIm25-regulated lncRNA acv3UTR promotes gastric tumorigenesis via miR-590-5p/YAP1 axis.
Liu K, Wang BJ, Han W, Chi CH, Gu C, Wang Y, Fu X, Huang W, Liu Z, Song X
Oncogene 2020 Apr;39(15):3075-3088
Oncogene 2020 Apr;39(15):3075-3088
MiR-194-5p inhibited metastasis and EMT of nephroblastoma cells through targeting Crk.
Liu H, Ren SY, Qu Y, Liu C, Zhang Y, Li XQ, Ma H
The Kaohsiung journal of medical sciences 2020 Apr;36(4):265-273
The Kaohsiung journal of medical sciences 2020 Apr;36(4):265-273
MTH1 Inhibitor TH287 Suppresses Gastric Cancer Development Through the Regulation of PI3K/AKT Signaling.
Zhan D, Zhang X, Li J, Ding X, Cui Y, Jia J
Cancer biotherapy & radiopharmaceuticals 2020 Apr;35(3):223-232
Cancer biotherapy & radiopharmaceuticals 2020 Apr;35(3):223-232
Regulation of hepatic glutamine metabolism by miR-122.
Sengupta D, Cassel T, Teng KY, Aljuhani M, Chowdhary VK, Hu P, Zhang X, Fan TW, Ghoshal K
Molecular metabolism 2020 Apr;34:174-186
Molecular metabolism 2020 Apr;34:174-186
Different Serotypes of Adeno-Associated Virus Vector- and Lentivirus-Mediated Tropism in Choroid Plexus by Intracerebroventricular Delivery.
Chen X, He Y, Tian Y, Wang Y, Wu Z, Lan T, Wang H, Cheng K, Xie P
Human gene therapy 2020 Apr;31(7-8):440-447
Human gene therapy 2020 Apr;31(7-8):440-447
Nicotinamide riboside rescues angiotensin II-induced cerebral small vessel disease in mice.
Li CC, Chen WX, Wang J, Xia M, Jia ZC, Guo C, Tang XQ, Li MX, Yin Y, Liu X, Feng H
CNS neuroscience & therapeutics 2020 Apr;26(4):438-447
CNS neuroscience & therapeutics 2020 Apr;26(4):438-447
Estrogen accelerates heart regeneration by promoting the inflammatory response in zebrafish.
Xu S, Xie F, Tian L, Fallah S, Babaei F, Manno SHC, Manno FAM, Zhu L, Wong KF, Liang Y, Ramalingam R, Sun L, Wang X, Plumb R, Gethings L, Lam YW, Cheng SH
The Journal of endocrinology 2020 Apr;245(1):39-51
The Journal of endocrinology 2020 Apr;245(1):39-51
Potent USP10/13 antagonist spautin-1 suppresses melanoma growth via ROS-mediated DNA damage and exhibits synergy with cisplatin.
Guo J, Zhang J, Liang L, Liu N, Qi M, Zhao S, Su J, Liu J, Peng C, Chen X, Liu H
Journal of cellular and molecular medicine 2020 Apr;24(7):4324-4340
Journal of cellular and molecular medicine 2020 Apr;24(7):4324-4340
METTL3/YTHDF2 m6 A axis promotes tumorigenesis by degrading SETD7 and KLF4 mRNAs in bladder cancer.
Xie H, Li J, Ying Y, Yan H, Jin K, Ma X, He L, Xu X, Liu B, Wang X, Zheng X, Xie L
Journal of cellular and molecular medicine 2020 Apr;24(7):4092-4104
Journal of cellular and molecular medicine 2020 Apr;24(7):4092-4104
MiR-210-3p-EphrinA3-PI3K/AKT axis regulates the progression of oral cancer.
Wang L, Song Y, Wang H, Liu K, Shao Z, Shang Z
Journal of cellular and molecular medicine 2020 Apr;24(7):4011-4022
Journal of cellular and molecular medicine 2020 Apr;24(7):4011-4022
Long noncoding RNA FBXL19-AS1 induces tumor growth and metastasis by sponging miR-203a-3p in lung adenocarcinoma.
Wang L, Zhang X, Liu Y, Xu S
Journal of cellular physiology 2020 Apr;235(4):3612-3625
Journal of cellular physiology 2020 Apr;235(4):3612-3625
Estradiol-17β regulates proliferation and apoptosis of sheep endometrial epithelial cells by regulating the relative abundance of YAP1.
An SY, Gao XX, Wang ZB, Liang YX, Wang ST, Xiao SH, Xia JT, You PH, Wang F, Zhang GM
Animal reproduction science 2020 Apr;215:106328
Animal reproduction science 2020 Apr;215:106328
Long non‑coding RNA MALAT1 regulates cholesterol accumulation in ox‑LDL‑induced macrophages via the microRNA‑17‑5p/ABCA1 axis.
Liu L, Tan L, Yao J, Yang L
Molecular medicine reports 2020 Apr;21(4):1761-1770
Molecular medicine reports 2020 Apr;21(4):1761-1770
C9orf72 associates with inactive Rag GTPases and regulates mTORC1-mediated autophagosomal and lysosomal biogenesis.
Wang M, Wang H, Tao Z, Xia Q, Hao Z, Prehn JHM, Zhen X, Wang G, Ying Z
Aging cell 2020 Apr;19(4):e13126
Aging cell 2020 Apr;19(4):e13126
Effects of propofol on LC3II and mTOR/p-mTOR expression during ischemia-reperfusion myocardium injury in rats with type 2 diabetes mellitus.
Wang Y, Zhang K, Qi X, Yang G, Wang H, Zhang Z, Yang B
Experimental and therapeutic medicine 2020 Apr;19(4):2441-2448
Experimental and therapeutic medicine 2020 Apr;19(4):2441-2448
Galantamine Inhibits Aβ1-42-Induced Neurotoxicity by Enhancing α7nAChR Expression as a Cargo Carrier for LC3 Binding and Aβ1-42 Engulfment During Autophagic Degradation.
Lin MW, Chen YH, Yang HB, Lin CC, Hung SY
Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics 2020 Apr;17(2):676-689
Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics 2020 Apr;17(2):676-689
Ehrlichia chaffeensis TRP120-mediated ubiquitination and proteasomal degradation of tumor suppressor FBW7 increases oncoprotein stability and promotes infection.
Wang JY, Zhu B, Patterson LL, Rogan MR, Kibler CE, McBride JW
PLoS pathogens 2020 Apr;16(4):e1008541
PLoS pathogens 2020 Apr;16(4):e1008541
Potential role of full-length and nonfull-length progranulin in affecting aortic valve calcification.
Huang G, An L, Fan M, Zhang M, Chen B, Zhu M, Wu J, Liu Y, Wang Y, Huang Q, Shi Q, Weng Y
Journal of molecular and cellular cardiology 2020 Apr;141:93-104
Journal of molecular and cellular cardiology 2020 Apr;141:93-104
Overcoming acquired resistance of EGFR-mutant NSCLC cells to the third generation EGFR inhibitor, osimertinib, with the natural product honokiol.
Zang H, Qian G, Arbiser J, Owonikoko TK, Ramalingam SS, Fan S, Sun SY
Molecular oncology 2020 Apr;14(4):882-895
Molecular oncology 2020 Apr;14(4):882-895
3,4,5-Tri-O-caffeoylquinic acid methyl ester isolated from Lonicera japonica Thunb. Flower buds facilitates hepatitis B virus replication in HepG2.2.15 cells.
Wan H, Ge L, Xiao L, Li J, Wu W, Peng S, Huang J, Zhou B, Zeng X
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2020 Apr;138:111250
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2020 Apr;138:111250
Photobiomodulation by diffusing optical fiber on spinal cord: A feasibility study in piglet model.
Liang Z, Lei T, Wang S, Zuo X, Li K, Song J, Sun J, Zhang J, Zheng Q, Kang X, Ma Y, Hu X, Ding T, Wang Z
Journal of biophotonics 2020 Apr;13(4):e201960022
Journal of biophotonics 2020 Apr;13(4):e201960022
Tissue Transglutaminase contributes to myelin phagocytosis in interleukin-4-treated human monocyte-derived macrophages.
Sestito C, Brevé JJP, Bol JGJM, Wilhelmus MMM, Drukarch B, van Dam AM
Cytokine 2020 Apr;128:155024
Cytokine 2020 Apr;128:155024
Prazosin inhibits the proliferation and survival of acute myeloid leukaemia cells through down-regulating TNS1.
Sun X, Yang S, Song W
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Apr;124:109731
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Apr;124:109731
Circ-IGF1R inhibits cell invasion and migration in non-small cell lung cancer.
Xu Z, Xiang W, Chen W, Sun Y, Qin F, Wei J, Yuan L, Zheng L, Li S
Thoracic cancer 2020 Apr;11(4):875-887
Thoracic cancer 2020 Apr;11(4):875-887
Low-dose lithium feeding increases the SERCA2a-to-phospholamban ratio, improving SERCA function in murine left ventricles.
Hamstra SI, Kurgan N, Baranowski RW, Qiu L, Watson CJF, Messner HN, MacPherson REK, MacNeil AJ, Roy BD, Fajardo VA
Experimental physiology 2020 Apr;105(4):666-675
Experimental physiology 2020 Apr;105(4):666-675
Dexmedetomidine alleviates postoperative cognitive dysfunction through circular RNA in aged rats.
Cao C, Deng F, Hu Y
3 Biotech 2020 Apr;10(4):176
3 Biotech 2020 Apr;10(4):176
Small Nucleolar RNA, C/D Box 16 (SNORD16) Acts as a Potential Prognostic Biomarker in Colon Cancer.
He JY, Liu X, Qi ZH, Wang Q, Lu WQ, Zhang QT, He SY, Wang ZD
Dose-response : a publication of International Hormesis Society 2020 Apr-Jun;18(2):1559325820917829
Dose-response : a publication of International Hormesis Society 2020 Apr-Jun;18(2):1559325820917829
PGN and LTA from Staphylococcus aureus Induced Inflammation and Decreased Lactation through Regulating DNA Methylation and Histone H3 Acetylation in Bovine Mammary Epithelial Cells.
Wu Y, Chen J, Sun Y, Dong X, Wang Z, Chen J, Dong G
Toxins 2020 Apr 9;12(4)
Toxins 2020 Apr 9;12(4)
Caspase-8 Induces Lysosome-Associated Cell Death in Cancer Cells.
Zhong B, Liu M, Bai C, Ruan Y, Wang Y, Qiu L, Hong Y, Wang X, Li L, Li B
Molecular therapy : the journal of the American Society of Gene Therapy 2020 Apr 8;28(4):1078-1091
Molecular therapy : the journal of the American Society of Gene Therapy 2020 Apr 8;28(4):1078-1091
Type 3 adenylyl cyclase in the MOE is involved in learning and memory in mice.
Liu X, Zhou Y, Yang D, Li S, Liu X, Wang Z
Behavioural brain research 2020 Apr 6;383:112533
Behavioural brain research 2020 Apr 6;383:112533
α-Tubulin detyrosination impairs mitotic error correction by suppressing MCAK centromeric activity.
Ferreira LT, Orr B, Rajendraprasad G, Pereira AJ, Lemos C, Lima JT, Guasch Boldú C, Ferreira JG, Barisic M, Maiato H
The Journal of cell biology 2020 Apr 6;219(4)
The Journal of cell biology 2020 Apr 6;219(4)
Impaired autophagic flux contributes to muscle atrophy in obesity by affecting muscle degradation and regeneration.
Fan Z, Xiao Q
Biochemical and biophysical research communications 2020 Apr 30;525(2):462-468
Biochemical and biophysical research communications 2020 Apr 30;525(2):462-468
The cellular expression and proteolytic processing of the amyloid precursor protein is independent of TDP-43.
Hicks DA, Jones AC, Pickering-Brown SM, Hooper NM
Bioscience reports 2020 Apr 30;40(4)
Bioscience reports 2020 Apr 30;40(4)
METTL3 is essential for postnatal development of brown adipose tissue and energy expenditure in mice.
Wang Y, Gao M, Zhu F, Li X, Yang Y, Yan Q, Jia L, Xie L, Chen Z
Nature communications 2020 Apr 3;11(1):1648
Nature communications 2020 Apr 3;11(1):1648
Breast cancer-derived exosomes transmit lncRNA SNHG16 to induce CD73+γδ1 Treg cells.
Ni C, Fang QQ, Chen WZ, Jiang JX, Jiang Z, Ye J, Zhang T, Yang L, Meng FB, Xia WJ, Zhong M, Huang J
Signal transduction and targeted therapy 2020 Apr 29;5(1):41
Signal transduction and targeted therapy 2020 Apr 29;5(1):41
Dimethyl itaconate, an itaconate derivative, exhibits immunomodulatory effects on neuroinflammation in experimental autoimmune encephalomyelitis.
Kuo PC, Weng WT, Scofield BA, Paraiso HC, Brown DA, Wang PY, Yu IC, Yen JH
Journal of neuroinflammation 2020 Apr 29;17(1):138
Journal of neuroinflammation 2020 Apr 29;17(1):138
ACE2 correlated with immune infiltration serves as a prognostic biomarker in endometrial carcinoma and renal papillary cell carcinoma: implication for COVID-19.
Yang J, Li H, Hu S, Zhou Y
Aging 2020 Apr 27;12(8):6518-6535
Aging 2020 Apr 27;12(8):6518-6535
PENK inhibits osteosarcoma cell migration by activating the PI3K/Akt signaling pathway.
Zhang HP, Yu ZL, Wu BB, Sun FR
Journal of orthopaedic surgery and research 2020 Apr 25;15(1):162
Journal of orthopaedic surgery and research 2020 Apr 25;15(1):162
Inhibition of cGAS-Mediated Interferon Response Facilitates Transgene Expression.
Fu Y, Fang Y, Lin Z, Yang L, Zheng L, Hu H, Yu T, Huang B, Chen S, Wang H, Xu S, Bao W, Chen Q, Sun L
iScience 2020 Apr 24;23(4):101026
iScience 2020 Apr 24;23(4):101026
4,5-di-O-caffeoylquinic acid methyl ester isolated from Lonicera japonica Thunb. targets the Keap1/Nrf2 pathway to attenuate H2O2-induced liver oxidative damage in HepG2 cells.
Xiao L, Liang S, Ge L, Wan H, Wu W, Fei J, Wu S, Zhou B, Zeng X
Phytomedicine : international journal of phytotherapy and phytopharmacology 2020 Apr 23;70:153219
Phytomedicine : international journal of phytotherapy and phytopharmacology 2020 Apr 23;70:153219
Pathogenic Variants in CEP85L Cause Sporadic and Familial Posterior Predominant Lissencephaly.
Tsai MH, Muir AM, Wang WJ, Kang YN, Yang KC, Chao NH, Wu MF, Chang YC, Porter BE, Jansen LA, Sebire G, Deconinck N, Fan WL, Su SC, Chung WH, Almanza Fuerte EP, Mehaffey MG, University of Washington Center for Mendelian Genomics., Ng CC, Chan CK, Lim KS, Leventer RJ, Lockhart PJ, Riney K, Damiano JA, Hildebrand MS, Mirzaa GM, Dobyns WB, Berkovic SF, Scheffer IE, Tsai JW, Mefford HC
Neuron 2020 Apr 22;106(2):237-245.e8
Neuron 2020 Apr 22;106(2):237-245.e8
The potential role of Krüppel-like factor 13 (Aj-klf13) in the intestine regeneration of sea cucumber Apostichopus japonicus.
Chen L, Yao F, Qin Y, Shao Y, Fang L, Yu X, Wang S, Hou L
Gene 2020 Apr 20;735:144407
Gene 2020 Apr 20;735:144407
Carnosol inhibits inflammasome activation by directly targeting HSP90 to treat inflammasome-mediated diseases.
Shi W, Xu G, Zhan X, Gao Y, Wang Z, Fu S, Qin N, Hou X, Ai Y, Wang C, He T, Liu H, Chen Y, Liu Y, Wang J, Niu M, Guo Y, Xiao X, Bai Z
Cell death & disease 2020 Apr 20;11(4):252
Cell death & disease 2020 Apr 20;11(4):252
Sitagliptin Inhibits Extracellular Matrix Accumulation and Proliferation in Lung Fibroblasts.
Liu X, Zhang T, Zhang C
Medical science monitor : international medical journal of experimental and clinical research 2020 Apr 17;26:e922644
Medical science monitor : international medical journal of experimental and clinical research 2020 Apr 17;26:e922644
Alamandine attenuates hepatic fibrosis by regulating autophagy induced by NOX4-dependent ROS.
Huang Y, Li Y, Lou A, Wang GZ, Hu Y, Zhang Y, Huang W, Wang J, Li Y, Zhu X, Chen T, Lin J, Meng Y, Li X
Clinical science (London, England : 1979) 2020 Apr 17;134(7):853-869
Clinical science (London, England : 1979) 2020 Apr 17;134(7):853-869
Reverse Genetics Reveals a Role of Rotavirus VP3 Phosphodiesterase Activity in Inhibiting RNase L Signaling and Contributing to Intestinal Viral Replication In Vivo.
Song Y, Feng N, Sanchez-Tacuba L, Yasukawa LL, Ren L, Silverman RH, Ding S, Greenberg HB
Journal of virology 2020 Apr 16;94(9)
Journal of virology 2020 Apr 16;94(9)
Induced CD10 expression during monocyte-to-macrophage differentiation identifies a unique subset of macrophages in pancreatic ductal adenocarcinoma.
Huang X, He C, Lin G, Lu L, Xing K, Hua X, Sun S, Mao Y, Song Y, Wang J, Li S
Biochemical and biophysical research communications 2020 Apr 16;524(4):1064-1071
Biochemical and biophysical research communications 2020 Apr 16;524(4):1064-1071
Zhx2 Accelerates Sepsis by Promoting Macrophage Glycolysis via Pfkfb3.
Wang Z, Kong L, Tan S, Zhang Y, Song X, Wang T, Lin Q, Wu Z, Xiang P, Li C, Gao L, Liang X, Ma C
Journal of immunology (Baltimore, Md. : 1950) 2020 Apr 15;204(8):2232-2241
Journal of immunology (Baltimore, Md. : 1950) 2020 Apr 15;204(8):2232-2241
NOD1 Promotes Antiviral Signaling by Binding Viral RNA and Regulating the Interaction of MDA5 and MAVS.
Wu XM, Zhang J, Li PW, Hu YW, Cao L, Ouyang S, Bi YH, Nie P, Chang MX
Journal of immunology (Baltimore, Md. : 1950) 2020 Apr 15;204(8):2216-2231
Journal of immunology (Baltimore, Md. : 1950) 2020 Apr 15;204(8):2216-2231
The circular RNA CDR1as regulate cell proliferation via TMED2 and TMED10.
Yang X, Li S, Wu Y, Ge F, Chen Y, Xiong Q
BMC cancer 2020 Apr 15;20(1):312
BMC cancer 2020 Apr 15;20(1):312
Betulinic Acid-Mediated Tuning of PERK/CHOP Signaling by Sp1 Inhibition as a Novel Therapeutic Strategy for Glioblastoma.
Lo WL, Hsu TI, Yang WB, Kao TJ, Wu MH, Huang YN, Yeh SH, Chuang JY
Cancers 2020 Apr 15;12(4)
Cancers 2020 Apr 15;12(4)
Interleukin 26 Skews Macrophage Polarization Towards M1 Phenotype by Activating cJUN and the NF-κB Pathway.
Lin YH, Wang YH, Peng YJ, Liu FC, Lin GJ, Huang SH, Sytwu HK, Cheng CP
Cells 2020 Apr 10;9(4)
Cells 2020 Apr 10;9(4)
Doxorubicin-polyglycerol-nanodiamond conjugates disrupt STAT3/IL-6-mediated reciprocal activation loop between glioblastoma cells and astrocytes.
Chen Z, Yuan SJ, Li K, Zhang Q, Li TF, An HC, Xu HZ, Yue Y, Han M, Xu YH, Komatsu N, Zhao L, Chen X
Journal of controlled release : official journal of the Controlled Release Society 2020 Apr 10;320:469-483
Journal of controlled release : official journal of the Controlled Release Society 2020 Apr 10;320:469-483
A Novel Rhynchophylline Analog, Y396, Inhibits Endothelial Dysfunction Induced by Oxidative Stress in Diabetes Through Epidermal Growth Factor Receptor.
Wang ZJ, Chang LL, Wu J, Pan HM, Zhang QY, Wang MJ, Xin XM, Luo SS, Chen JA, Gu XF, Guo W, Zhu YZ
Antioxidants & redox signaling 2020 Apr 10;32(11):743-765
Antioxidants & redox signaling 2020 Apr 10;32(11):743-765
The HIV-1 capsid-binding host factor CPSF6 is post-transcriptionally regulated by the cellular microRNA miR-125b.
Chaudhuri E, Dash S, Balasubramaniam M, Padron A, Holland J, Sowd GA, Villalta F, Engelman AN, Pandhare J, Dash C
The Journal of biological chemistry 2020 Apr 10;295(15):5081-5094
The Journal of biological chemistry 2020 Apr 10;295(15):5081-5094
Paraoxonase 3 functions as a chaperone to decrease functional expression of the epithelial sodium channel.
Shi S, Montalbetti N, Wang X, Rush BM, Marciszyn AL, Baty CJ, Tan RJ, Carattino MD, Kleyman TR
The Journal of biological chemistry 2020 Apr 10;295(15):4950-4962
The Journal of biological chemistry 2020 Apr 10;295(15):4950-4962
FTO promotes cell proliferation and migration in esophageal squamous cell carcinoma through up-regulation of MMP13.
Liu S, Huang M, Chen Z, Chen J, Chao Q, Yin X, Quan M
Experimental cell research 2020 Apr 1;389(1):111894
Experimental cell research 2020 Apr 1;389(1):111894
Adipose-derived exosomes protect the pulmonary endothelial barrier in ventilator-induced lung injury by inhibiting the TRPV4/Ca2+ signaling pathway.
Yu Q, Wang D, Wen X, Tang X, Qi D, He J, Zhao Y, Deng W, Zhu T
American journal of physiology. Lung cellular and molecular physiology 2020 Apr 1;318(4):L723-L741
American journal of physiology. Lung cellular and molecular physiology 2020 Apr 1;318(4):L723-L741
miR-524-5p inhibits angiogenesis through targeting WNK1 in colon cancer cells.
Li X, Li Z, Zhu Y, Li Z, Yao L, Zhang L, Yuan L, Shang Y, Liu J, Li C
American journal of physiology. Gastrointestinal and liver physiology 2020 Apr 1;318(4):G827-G839
American journal of physiology. Gastrointestinal and liver physiology 2020 Apr 1;318(4):G827-G839
OTUD1 Negatively Regulates Type I IFN Induction by Disrupting Noncanonical Ubiquitination of IRF3.
Zhang Z, Wang D, Wang P, Zhao Y, You F
Journal of immunology (Baltimore, Md. : 1950) 2020 Apr 1;204(7):1904-1918
Journal of immunology (Baltimore, Md. : 1950) 2020 Apr 1;204(7):1904-1918
Lanthanum chloride impairs spatial learning and memory by inducing [Ca2+]m overload, mitochondrial fission-fusion disorder and excessive mitophagy in hippocampal nerve cells of rats.
Yu M, Yang J, Gao X, Sun W, Liu S, Han Y, Lu X, Jin C, Wu S, Cai Y
Metallomics : integrated biometal science 2020 Apr 1;12(4):592-606
Metallomics : integrated biometal science 2020 Apr 1;12(4):592-606
The protective effects of β-sitosterol and vermicularin from Thamnolia vermicularis (Sw.) Ach. against skin aging in vitro.
Haiyuan YU, Shen X, Liu D, Hong M, Lu Y
Anais da Academia Brasileira de Ciencias 2019;91(4):e20181088
Anais da Academia Brasileira de Ciencias 2019;91(4):e20181088
Tumor-associated macrophages (TAMs) depend on Shp2 for their anti-tumor roles in colorectal cancer.
Wang S, Yao Y, Li H, Zheng G, Lu S, Chen W
American journal of cancer research 2019;9(9):1957-1969
American journal of cancer research 2019;9(9):1957-1969
Progerin accumulation in nucleus pulposus cells impairs mitochondrial function and induces intervertebral disc degeneration and therapeutic effects of sulforaphane.
Xu X, Wang D, Zheng C, Gao B, Fan J, Cheng P, Liu B, Yang L, Luo Z
Theranostics 2019;9(8):2252-2267
Theranostics 2019;9(8):2252-2267
Overexpression of MEF2D contributes to oncogenic malignancy and chemotherapeutic resistance in ovarian carcinoma.
Li X, Zhang Y, Chai X, Zhou S, Zhang H, He J, Zhou R, Cai L, Chen L, Tao G
American journal of cancer research 2019;9(5):887-905
American journal of cancer research 2019;9(5):887-905
Changes in the intestinal microecology induced by bacillus subtilis inhibit the occurrence of ulcerative colitis and associated cancers: a study on the mechanisms.
Wu C, Ouyang M, Guo Q, Jia J, Liu R, Jiang Y, Wu M, Shen S
American journal of cancer research 2019;9(5):872-886
American journal of cancer research 2019;9(5):872-886
Collaborative ISL1/GATA3 interaction in controlling neuroblastoma oncogenic pathways overlapping with but distinct from MYCN.
Zhang Q, Zhang Q, Jiang X, Ye Y, Liao H, Zhu F, Yan J, Luo L, Tian L, Jiang C, Chen Y, Liang X, Sun Y
Theranostics 2019;9(4):986-1000
Theranostics 2019;9(4):986-1000
CACYBP Enhances Cytoplasmic Retention of P27Kip1 to Promote Hepatocellular Carcinoma Progression in the Absence of RNF41 Mediated Degradation.
Lian YF, Huang YL, Zhang YJ, Chen DM, Wang JL, Wei H, Bi YH, Jiang ZW, Li P, Chen MS, Huang YH
Theranostics 2019;9(26):8392-8408
Theranostics 2019;9(26):8392-8408
Inhibition of SMYD2 suppresses tumor progression by down-regulating microRNA-125b and attenuates multi-drug resistance in renal cell carcinoma.
Yan L, Ding B, Liu H, Zhang Y, Zeng J, Hu J, Yao W, Yu G, An R, Chen Z, Ye Z, Xing J, Xiao K, Wu L, Xu H
Theranostics 2019;9(26):8377-8391
Theranostics 2019;9(26):8377-8391
A Compound AC1Q3QWB Selectively Disrupts HOTAIR-Mediated Recruitment of PRC2 and Enhances Cancer Therapy of DZNep.
Li Y, Ren Y, Wang Y, Tan Y, Wang Q, Cai J, Zhou J, Yang C, Zhao K, Yi K, Jin W, Wang L, Liu M, Yang J, Li M, Kang C
Theranostics 2019;9(16):4608-4623
Theranostics 2019;9(16):4608-4623
Autophagy impairment contributes to PBDE-47-induced developmental neurotoxicity and its relationship with apoptosis.
Li P, Ma R, Dong L, Liu L, Zhou G, Tian Z, Zhao Q, Xia T, Zhang S, Wang A
Theranostics 2019;9(15):4375-4390
Theranostics 2019;9(15):4375-4390
Long noncoding RNA GAS5 inhibits metastasis by targeting miR-182/ANGPTL1 in hepatocellular carcinoma.
Chen F, Li Y, Li M, Wang L
American journal of cancer research 2019;9(1):108-121
American journal of cancer research 2019;9(1):108-121
CRISPRa-mediated FOXP3 gene upregulation in mammalian cells.
Forstnerič V, Oven I, Ogorevc J, Lainšček D, Praznik A, Lebar T, Jerala R, Horvat S
Cell & bioscience 2019;9:93
Cell & bioscience 2019;9:93
Aurora-A Induces Chemoresistance Through Activation of the AKT/mTOR Pathway in Endometrial Cancer.
Wu J, Cheng Z, Xu X, Fu J, Wang K, Liu T, Wu C, Kong X, Yang Q, Yan G, Zhou H
Frontiers in oncology 2019;9:422
Frontiers in oncology 2019;9:422
Antitumor Effects of Berberine on Gliomas via Inactivation of Caspase-1-Mediated IL-1β and IL-18 Release.
Tong L, Xie C, Wei Y, Qu Y, Liang H, Zhang Y, Xu T, Qian X, Qiu H, Deng H
Frontiers in oncology 2019;9:364
Frontiers in oncology 2019;9:364
A Novel Citrullinated Modification of Histone 3 and Its Regulatory Mechanisms Related to IPO-38 Antibody-Labeled Protein.
Song S, Xiang Z, Li J, Ji J, Yan R, Zhu Z, Yu Y
Frontiers in oncology 2019;9:304
Frontiers in oncology 2019;9:304
Nociceptin Receptor Is Overexpressed in Non-small Cell Lung Cancer and Predicts Poor Prognosis.
Wang K, Zheng Y, Yang Y, Wang J, Li B, Wei F, Zhao H, Ren X
Frontiers in oncology 2019;9:235
Frontiers in oncology 2019;9:235
Identification of a Two-Gene (PML-EPB41) Signature With Independent Prognostic Value in Osteosarcoma.
Liu S, Liu J, Yu X, Shen T, Fu Q
Frontiers in oncology 2019;9:1578
Frontiers in oncology 2019;9:1578
PA28α/β Promote Breast Cancer Cell Invasion and Metastasis via Down-Regulation of CDK15.
Li S, Dai X, Gong K, Song K, Tai F, Shi J
Frontiers in oncology 2019;9:1283
Frontiers in oncology 2019;9:1283
Long Non-coding RNA SNHG12 Functions as a Competing Endogenous RNA to Regulate MDM4 Expression by Sponging miR-129-5p in Clear Cell Renal Cell Carcinoma.
Wu Z, Chen D, Wang K, Cao C, Xu X
Frontiers in oncology 2019;9:1260
Frontiers in oncology 2019;9:1260
The Tumor Suppressor Role of Zinc Finger Protein 671 (ZNF671) in Multiple Tumors Based on Cancer Single-Cell Sequencing.
Zhang J, Luo J, Jiang H, Xie T, Zheng J, Tian Y, Li R, Wang B, Lin J, Xu A, Huang X, Yuan Y
Frontiers in oncology 2019;9:1214
Frontiers in oncology 2019;9:1214
MRPS30-DT Knockdown Inhibits Breast Cancer Progression by Targeting Jab1/Cops5.
Wu B, Pan Y, Liu G, Yang T, Jin Y, Zhou F, Wei Y
Frontiers in oncology 2019;9:1170
Frontiers in oncology 2019;9:1170
FA2H Exhibits Tumor Suppressive Roles on Breast Cancers via Cancer Stemness Control.
Dai X, Zhang S, Cheng H, Cai D, Chen X, Huang Z
Frontiers in oncology 2019;9:1089
Frontiers in oncology 2019;9:1089
SEMA3C Promotes Cervical Cancer Growth and Is Associated With Poor Prognosis.
Liu R, Shuai Y, Luo J, Zhang Z
Frontiers in oncology 2019;9:1035
Frontiers in oncology 2019;9:1035
Heatstroke-induced hepatocyte exosomes promote liver injury by activating the NOD-like receptor signaling pathway in mice.
Li Y, Zhu X, Zhang M, Tong H, Su L
PeerJ 2019;7:e8216
PeerJ 2019;7:e8216
Structural basis for the recognition of K48-linked Ub chain by proteasomal receptor Rpn13.
Liu Z, Dong X, Yi HW, Yang J, Gong Z, Wang Y, Liu K, Zhang WP, Tang C
Cell discovery 2019;5:19
Cell discovery 2019;5:19
Loss of the Golgi Matrix Protein 130 Cause Aberrant IgA1 Glycosylation in IgA Nephropathy.
Wang C, Ye M, Zhao Q, Xia M, Liu D, He L, Chen G, Peng Y, Liu H
American journal of nephrology 2019;49(4):307-316
American journal of nephrology 2019;49(4):307-316
Hsa_circ_001569 is an unfavorable prognostic factor and promotes cell proliferation and metastasis by modulating PI3K-AKT pathway in breast cancer.
Xu JH, Wang Y, Xu D
Cancer biomarkers : section A of Disease markers 2019;25(2):193-201
Cancer biomarkers : section A of Disease markers 2019;25(2):193-201
Long noncoding RNA glutathione peroxidase 3-antisense inhibits lens epithelial cell apoptosis by upregulating glutathione peroxidase 3 expression in age-related cataract.
Tu Y, Li L, Qin B, Wu J, Cheng T, Kang L, Guan H
Molecular vision 2019;25:734-744
Molecular vision 2019;25:734-744
The long noncoding RNA LINC00483 promotes lung adenocarcinoma progression by sponging miR-204-3p.
Yang S, Liu T, Sun Y, Liang X
Cellular & molecular biology letters 2019;24:70
Cellular & molecular biology letters 2019;24:70
Effect of MicroRNA-20a on Osteogenic Differentiation of Human Adipose Tissue-Derived Stem Cells.
Luo T, Yang X, Sun Y, Huang X, Zou L, Liu J
Cells, tissues, organs 2019;208(3-4):148-157
Cells, tissues, organs 2019;208(3-4):148-157
Xiaokeping Mixture Attenuates Diabetic Kidney Disease by Modulating TGF-β/Smad Pathway in db/db Mice.
Yang B, Xia Z, Xin C, Ma C, Zhang F
Evidence-based complementary and alternative medicine : eCAM 2019;2019:9241896
Evidence-based complementary and alternative medicine : eCAM 2019;2019:9241896
Mangiferin Prevents TBHP-Induced Apoptosis and ECM Degradation in Mouse Osteoarthritic Chondrocytes via Restoring Autophagy and Ameliorates Murine Osteoarthritis.
Li Y, Wu Y, Jiang K, Han W, Zhang J, Xie L, Liu Y, Xiao J, Wang X
Oxidative medicine and cellular longevity 2019;2019:8783197
Oxidative medicine and cellular longevity 2019;2019:8783197
A Peptide Analogue of Selectin Ligands Attenuated Atherosclerosis by Inhibiting Monocyte Activation.
Ye Z, Zhang S, Liu Y, Wang S, Zhang J, Huang R
Mediators of inflammation 2019;2019:8709583
Mediators of inflammation 2019;2019:8709583
Modulations of Histone Deacetylase 2 Offer a Protective Effect through the Mitochondrial Apoptosis Pathway in Acute Liver Failure.
Wang Y, Yang F, Jiao FZ, Chen Q, Zhang WB, Wang LW, Gong ZJ
Oxidative medicine and cellular longevity 2019;2019:8173016
Oxidative medicine and cellular longevity 2019;2019:8173016
Therapeutic Effects of Human Urine-Derived Stem Cells in a Rat Model of Cisplatin-Induced Acute Kidney Injury In Vivo and In Vitro.
Sun B, Luo X, Yang C, Liu P, Yang Y, Dong X, Yang Z, Xu J, Zhang Y, Li L
Stem cells international 2019;2019:8035076
Stem cells international 2019;2019:8035076
Targeting INHBA in Ovarian Cancer Cells Suppresses Cancer Xenograft Growth by Attenuating Stromal Fibroblast Activation.
Li X, Yang Z, Xu S, Wang Z, Jin P, Yang X, Zhang Z, Wang Y, Wei X, Fang T, Gao Q
Disease markers 2019;2019:7275289
Disease markers 2019;2019:7275289
Abnormal Ribosome Biogenesis Partly Induced p53-Dependent Aortic Medial Smooth Muscle Cell Apoptosis and Oxidative Stress.
Wu Q, Hong J, Wang Z, Hu J, Chen R, Hu Z, Li B, Hu X, Zhang Z, Ruan Y
Oxidative medicine and cellular longevity 2019;2019:7064319
Oxidative medicine and cellular longevity 2019;2019:7064319
Pretreatment with AM1241 Enhances the Analgesic Effect of Intrathecally Administrated Mesenchymal Stem Cells.
Xie J, Ren J, Liu N, Wu C, Xiao D, Luo H, Du J
Stem cells international 2019;2019:7025473
Stem cells international 2019;2019:7025473
Effect of YAP on an Immortalized Periodontal Ligament Stem Cell Line.
Chen X, Wang Q, Gu K, Li A, Fu X, Wang Y, Gu W, Wen Y
Stem cells international 2019;2019:6804036
Stem cells international 2019;2019:6804036
Bufei Qingyu Granules Inhibit the Development of Systemic Sclerosis via Notch-1/Jagged-2 Signaling Pathway.
Su M, Tian F, Ouyang B, Wu X, Guo F, Chen H, Zhu X, Chen J, Qian X
Evidence-based complementary and alternative medicine : eCAM 2019;2019:6709278
Evidence-based complementary and alternative medicine : eCAM 2019;2019:6709278
Melatonin Rescued Reactive Oxygen Species-Impaired Osteogenesis of Human Bone Marrow Mesenchymal Stem Cells in the Presence of Tumor Necrosis Factor-Alpha.
Qiu X, Wang X, Qiu J, Zhu Y, Liang T, Gao B, Wu Z, Lian C, Peng Y, Liang A, Su P, Huang D
Stem cells international 2019;2019:6403967
Stem cells international 2019;2019:6403967
Hepatitis B Virus X Protein-Induced RORγ Expression to Promote the Migration and Proliferation of Hepatocellular Carcinoma.
Huang Y, Liang H, He C, Peng F
BioMed research international 2019;2019:5407126
BioMed research international 2019;2019:5407126
Identification of Upregulated HNRNPs Associated with Poor Prognosis in Pancreatic Cancer.
Qiao L, Xie N, Bai Y, Li Y, Shi Y, Wang J, Liu N
BioMed research international 2019;2019:5134050
BioMed research international 2019;2019:5134050
N-Acetylcysteine Attenuates Cisplatin-Induced Acute Kidney Injury by Inhibiting the C5a Receptor.
Huang S, You J, Wang K, Li Y, Zhang Y, Wei H, Liang X, Liu Y
BioMed research international 2019;2019:4805853
BioMed research international 2019;2019:4805853
NANOG Attenuates Hair Follicle-Derived Mesenchymal Stem Cell Senescence by Upregulating PBX1 and Activating AKT Signaling.
Liu F, Shi J, Zhang Y, Lian A, Han X, Zuo K, Liu M, Zheng T, Zou F, Liu X, Jin M, Mu Y, Li G, Su G, Liu J
Oxidative medicine and cellular longevity 2019;2019:4286213
Oxidative medicine and cellular longevity 2019;2019:4286213
Cul4a as a New Interaction Protein of PARP1 Inhibits Oxidative Stress-Induced H9c2 Cell Apoptosis.
Ye N, Zhang N, Zhang Y, Qian H, Wu B, Sun Y
Oxidative medicine and cellular longevity 2019;2019:4273261
Oxidative medicine and cellular longevity 2019;2019:4273261
Bu Shen Zhu Yun Decoction Improves Endometrial Receptivity via VEGFR-2-Mediated Angiogenesis.
Li L, Jiang H, Wei X, Geng D, He M, Du H
Evidence-based complementary and alternative medicine : eCAM 2019;2019:3949824
Evidence-based complementary and alternative medicine : eCAM 2019;2019:3949824
Loss of SDC1 Expression Is Associated with Poor Prognosis of Colorectal Cancer Patients in Northern China.
Li K, Li L, Wu X, Yu J, Ma H, Zhang R, Li Y, Wang W
Disease markers 2019;2019:3768708
Disease markers 2019;2019:3768708
Genetically Modified Porcine Mesenchymal Stem Cells by Lentiviral Tbx18 Create a Biological Pacemaker.
Hu Y, Li N, Liu L, Zhang H, Xue X, Shao X, Zhang Y, Lang X
Stem cells international 2019;2019:3621314
Stem cells international 2019;2019:3621314
Protocatechuic Acid-Mediated miR-219a-5p Activation Inhibits the p66shc Oxidant Pathway to Alleviate Alcoholic Liver Injury.
Fu R, Zhou J, Wang R, Sun R, Feng D, Wang Z, Zhao Y, Lv L, Tian X, Yao J
Oxidative medicine and cellular longevity 2019;2019:3527809
Oxidative medicine and cellular longevity 2019;2019:3527809
Upregulation of UCP2 Expression Protects against LPS-Induced Oxidative Stress and Apoptosis in Cardiomyocytes.
Huang J, Peng W, Zheng Y, Hao H, Li S, Yao Y, Ding Y, Zhang J, Lyu J, Zeng Q
Oxidative medicine and cellular longevity 2019;2019:2758262
Oxidative medicine and cellular longevity 2019;2019:2758262
Identification of CTRP1 as a Prognostic Biomarker and Oncogene in Human Glioblastoma.
Chen L, Su G
BioMed research international 2019;2019:2582416
BioMed research international 2019;2019:2582416
A regulatory circuit of circ-MTO1/miR-17/QKI-5 inhibits the proliferation of lung adenocarcinoma.
Zhang B, Chen M, Jiang N, Shi K, Qian R
Cancer biology & therapy 2019;20(8):1127-1135
Cancer biology & therapy 2019;20(8):1127-1135
Long non-coding RNA ARAP1-AS1 promotes the progression of bladder cancer by regulating miR-4735-3p/NOTCH2 axis.
Teng J, Ai X, Jia Z, Wang K, Guan Y, Guo Y
Cancer biology & therapy 2019;20(4):552-561
Cancer biology & therapy 2019;20(4):552-561
The m6A eraser FTO facilitates proliferation and migration of human cervical cancer cells.
Zou D, Dong L, Li C, Yin Z, Rao S, Zhou Q
Cancer cell international 2019;19:321
Cancer cell international 2019;19:321
The long noncoding RNA PCGEM1 promotes cell proliferation, migration and invasion via targeting the miR-182/FBXW11 axis in cervical cancer.
Zhang Q, Zheng J, Liu L
Cancer cell international 2019;19:304
Cancer cell international 2019;19:304
LncRNA DANCR promotes the proliferation, migration, and invasion of tongue squamous cell carcinoma cells through miR-135a-5p/KLF8 axis.
Zheng Y, Zheng B, Meng X, Yan Y, He J, Liu Y
Cancer cell international 2019;19:302
Cancer cell international 2019;19:302
Strand-specific miR-28-3p and miR-28-5p have differential effects on nasopharyngeal cancer cells proliferation, apoptosis, migration and invasion.
Lv Y, Yang H, Ma X, Wu G
Cancer cell international 2019;19:187
Cancer cell international 2019;19:187
Methods for Monitoring Autophagy in Silkworm Organs.
Montali A, Casartelli M, Bruno D, Grimaldi A, Tettamanti G
Methods in molecular biology (Clifton, N.J.) 2019;1854:159-174
Methods in molecular biology (Clifton, N.J.) 2019;1854:159-174
MicroRNA-29a is a key regulon that regulates BRD4 and mitigates liver fibrosis in mice by inhibiting hepatic stellate cell activation.
Huang YH, Kuo HC, Yang YL, Wang FS
International journal of medical sciences 2019;16(2):212-220
International journal of medical sciences 2019;16(2):212-220
LncRNA SNHG6 promotes proliferation, invasion and migration in colorectal cancer cells by activating TGF-β/Smad signaling pathway via targeting UPF1 and inducing EMT via regulation of ZEB1.
Wang X, Lai Q, He J, Li Q, Ding J, Lan Z, Gu C, Yan Q, Fang Y, Zhao X, Liu S
International journal of medical sciences 2019;16(1):51-59
International journal of medical sciences 2019;16(1):51-59
Ccr7 null mice are protected against diet-induced obesity via Ucp1 upregulation and enhanced energy expenditure.
Sano T, Sanada T, Sotomaru Y, Shinjo T, Iwashita M, Yamashita A, Fukuda T, Sanui T, Asano T, Kanematsu T, Nishimura F
Nutrition & metabolism 2019;16:43
Nutrition & metabolism 2019;16:43
Hypericin maintians PDX1 expression via the Erk pathway and protects islet β-cells against glucotoxicity and lipotoxicity.
Liang C, Hao F, Yao X, Qiu Y, Liu L, Wang S, Yu C, Song Z, Bao Y, Yi J, Huang Y, Wu Y, Zheng L, Sun Y, Wang G, Yang X, Yang S, Sun L, Li Y
International journal of biological sciences 2019;15(7):1472-1487
International journal of biological sciences 2019;15(7):1472-1487
KLF4-Mediated CDH3 Upregulation Suppresses Human Hepatoma Cell Growth and Migration via GSK-3β Signaling.
Li L, Yu S, Wu Q, Dou N, Li Y, Gao Y
International journal of biological sciences 2019;15(5):953-961
International journal of biological sciences 2019;15(5):953-961
Taurine Transporter Regulates Adipogenic Differentiation of Human Adipose-Derived Stem Cells through Affecting Wnt/β-catenin Signaling Pathway.
Hou X, Wang Z, Ding F, He Y, Wang P, Liu X, Xu F, Wang J, Yang Y
International journal of biological sciences 2019;15(5):1104-1112
International journal of biological sciences 2019;15(5):1104-1112
Upregulated MMP28 in Hepatocellular Carcinoma Promotes Metastasis via Notch3 Signaling and Predicts Unfavorable Prognosis.
Zhou J, Zheng X, Feng M, Mo Z, Shan Y, Wang Y, Jin J
International journal of biological sciences 2019;15(4):812-825
International journal of biological sciences 2019;15(4):812-825
Inhibition of Heme Oxygenase-1 enhances hyperthermia-induced autophagy and antiviral effect.
Yang Y, Wang HX, Zhang L, Huo W, Li XD, Qi RQ, Song XY, Wei S, Gao XH, Han S, Cao L
International journal of biological sciences 2019;15(3):568-578
International journal of biological sciences 2019;15(3):568-578
MiR-93 regulates vascular smooth muscle cell proliferation, and neointimal formation through targeting Mfn2.
Feng S, Gao L, Zhang D, Tian X, Kong L, Shi H, Wu L, Huang Z, Du B, Liang C, Zhang Y, Yao R
International journal of biological sciences 2019;15(12):2615-2626
International journal of biological sciences 2019;15(12):2615-2626
Muscle Injury Associated Elevated Oxidative Stress and Abnormal Myogenesis in Patients with Idiopathic Scoliosis.
Li J, Tang M, Yang G, Wang L, Gao Q, Zhang H
International journal of biological sciences 2019;15(12):2584-2595
International journal of biological sciences 2019;15(12):2584-2595
Resveratrol induced premature senescence and inhibited epithelial-mesenchymal transition of cancer cells via induction of tumor suppressor Rad9.
Chen KY, Chen CC, Chang YC, Chang MC
PloS one 2019;14(7):e0219317
PloS one 2019;14(7):e0219317
Progranulin deficiency leads to reduced glucocerebrosidase activity.
Zhou X, Paushter DH, Pagan MD, Kim D, Nunez Santos M, Lieberman RL, Overkleeft HS, Sun Y, Smolka MB, Hu F
PloS one 2019;14(7):e0212382
PloS one 2019;14(7):e0212382
Radiotherapy resistance acquisition in Glioblastoma. Role of SOCS1 and SOCS3.
Ventero MP, Fuentes-Baile M, Quereda C, Perez-Valeciano E, Alenda C, Garcia-Morales P, Esposito D, Dorado P, Manuel Barbera V, Saceda M
PloS one 2019;14(2):e0212581
PloS one 2019;14(2):e0212581
P16 methylation increases the sensitivity of cancer cells to the CDK4/6 inhibitor palbociclib.
Li P, Zhang X, Gu L, Zhou J, Deng D
PloS one 2019;14(10):e0223084
PloS one 2019;14(10):e0223084
Porous Se@SiO2 nanospheres attenuate ischemia/reperfusion (I/R)-induced acute kidney injury (AKI) and inflammation by antioxidative stress.
Zheng Z, Deng G, Qi C, Xu Y, Liu X, Zhao Z, Zhang Z, Chu Y, Wu H, Liu J
International journal of nanomedicine 2019;14:215-229
International journal of nanomedicine 2019;14:215-229
Long-Term Effects of Zinc Deficiency and Zinc Supplementation on Developmental Seizure-Induced Brain Damage and the Underlying GPR39/ZnT-3 and MBP Expression in the Hippocampus.
Chen NN, Zhao DJ, Sun YX, Wang DD, Ni H
Frontiers in neuroscience 2019;13:920
Frontiers in neuroscience 2019;13:920
Effects of Acupuncture on Behavioral Stereotypies and Brain Dopamine System in Mice as a Model of Tourette Syndrome.
Lin L, Yu L, Xiang H, Hu X, Yuan X, Zhu H, Li H, Zhang H, Hou T, Cao J, Wu S, Su W, Li M
Frontiers in behavioral neuroscience 2019;13:239
Frontiers in behavioral neuroscience 2019;13:239
Calsyntenin-1 Negatively Regulates ICAM5 Accumulation in Postsynaptic Membrane and Influences Dendritic Spine Maturation in a Mouse Model of Fragile X Syndrome.
Cheng K, Chen YS, Yue CX, Zhang SM, Pei YP, Cheng GR, Liu D, Xu L, Dong HX, Zeng Y
Frontiers in neuroscience 2019;13:1098
Frontiers in neuroscience 2019;13:1098
Osteoprotegerin promotes islet β cell proliferation in intrauterine growth retardation rats through the PI3K/AKT/FoxO1 pathway.
Tang S, Xin Y, Yang M, Zhang D, Xu C
International journal of clinical and experimental pathology 2019;12(6):2324-2338
International journal of clinical and experimental pathology 2019;12(6):2324-2338
CD147 promotes cervical cancer migration and invasion by up-regulating fatty acid synthase expression.
Guo W, Abudumijiti H, Xu L, Hasim A
International journal of clinical and experimental pathology 2019;12(12):4280-4288
International journal of clinical and experimental pathology 2019;12(12):4280-4288
CLK3 Is A Direct Target Of miR-144 And Contributes To Aggressive Progression In Hepatocellular Carcinoma.
Li H, Cui X, Hu Q, Chen X, Zhou P
OncoTargets and therapy 2019;12:9201-9213
OncoTargets and therapy 2019;12:9201-9213
Downregulation of CENPK suppresses hepatocellular carcinoma malignant progression through regulating YAP1.
Wang J, Li H, Xia C, Yang X, Dai B, Tao K, Dou K
OncoTargets and therapy 2019;12:869-882
OncoTargets and therapy 2019;12:869-882
INPP4B As A Prognostic And Diagnostic Marker Regulates Cell Growth Of Pancreatic Cancer Via Activating AKT.
Zhai S, Liu Y, Lu X, Qian H, Tang X, Cheng X, Wang Y, Shi Y, Deng X
OncoTargets and therapy 2019;12:8287-8299
OncoTargets and therapy 2019;12:8287-8299
GADD45a Mediated Cell Cycle Inhibition Is Regulated By P53 In Bladder Cancer.
Han N, Yuan F, Xian P, Liu N, Liu J, Zhang H, Zhang H, Yao K, Yuan G
OncoTargets and therapy 2019;12:7591-7599
OncoTargets and therapy 2019;12:7591-7599
MicroRNA-217 acts as a tumor suppressor and correlates with the chemoresistance of cervical carcinoma to cisplatin.
Yin Z, Ren W
OncoTargets and therapy 2019;12:759-771
OncoTargets and therapy 2019;12:759-771
GJB4 promotes gastric cancer cell proliferation and migration via Wnt/CTNNB1 pathway.
Liu G, Pang Y, Zhang Y, Fu H, Xiong W, Zhang Y
OncoTargets and therapy 2019;12:6745-6755
OncoTargets and therapy 2019;12:6745-6755
GPX2 suppression of H2O2 stress regulates cervical cancer metastasis and apoptosis via activation of the β-catenin-WNT pathway.
Wang Y, Cao P, Alshwmi M, Jiang N, Xiao Z, Jiang F, Gu J, Wang X, Sun X, Li S
OncoTargets and therapy 2019;12:6639-6651
OncoTargets and therapy 2019;12:6639-6651
tRNA-derived fragment tRF-03357 promotes cell proliferation, migration and invasion in high-grade serous ovarian cancer.
Zhang M, Li F, Wang J, He W, Li Y, Li H, Wei Z, Cao Y
OncoTargets and therapy 2019;12:6371-6383
OncoTargets and therapy 2019;12:6371-6383
14-Deoxycoleon U-induced endoplasmic reticulum stress-mediated apoptosis, autophagy, and cell cycle arrest in lung adenocarcinoma.
Peng X, Tu Y, Fu S, Xia Y, Ma C, Yang Y, Wu H, Liu Y, You P
OncoTargets and therapy 2019;12:5955-5965
OncoTargets and therapy 2019;12:5955-5965
Diallyl disulfide inhibits colon cancer metastasis by suppressing Rac1-mediated epithelial-mesenchymal transition.
Xia L, Lin J, Su J, Oyang L, Wang H, Tan S, Tang Y, Chen X, Liu W, Luo X, Tian Y, Liang J, Su Q, Liao Q, Zhou Y
OncoTargets and therapy 2019;12:5713-5728
OncoTargets and therapy 2019;12:5713-5728
LncRNA FENDRR attenuates colon cancer progression by repression of SOX4 protein.
Liu J, Du W
OncoTargets and therapy 2019;12:4287-4295
OncoTargets and therapy 2019;12:4287-4295
Exosomal Tenascin-c induces proliferation and invasion of pancreatic cancer cells by WNT signaling.
Qian S, Tan X, Liu X, Liu P, Wu Y
OncoTargets and therapy 2019;12:3197-3205
OncoTargets and therapy 2019;12:3197-3205
Silencing UBE4B induces nasopharyngeal carcinoma apoptosis through the activation of caspase3 and p53.
Weng C, Chen Y, Wu Y, Liu X, Mao H, Fang X, Li B, Wang L, Guan M, Liu G, Lu L, Yuan Y
OncoTargets and therapy 2019;12:2553-2561
OncoTargets and therapy 2019;12:2553-2561
AdipoRon Alleviates Free Fatty Acid-Induced Myocardial Cell Injury Via Suppressing Nlrp3 Inflammasome Activation.
Zhang YZ, Zhang YL, Huang Q, Huang C, Jiang ZL, Cai F, Shen JF
Diabetes, metabolic syndrome and obesity : targets and therapy 2019;12:2165-2179
Diabetes, metabolic syndrome and obesity : targets and therapy 2019;12:2165-2179
RRAD suppresses the Warburg effect by downregulating ACTG1 in hepatocellular carcinoma.
Yan Y, Xu H, Zhang L, Zhou X, Qian X, Zhou J, Huang Y, Ge W, Wang W
OncoTargets and therapy 2019;12:1691-1703
OncoTargets and therapy 2019;12:1691-1703
Upregulation of STC2 in colorectal cancer and its clinicopathological significance.
Zhang C, Chen S, Ma X, Yang Q, Su F, Shu X, Xie W, Feng M, Xiong B
OncoTargets and therapy 2019;12:1249-1258
OncoTargets and therapy 2019;12:1249-1258
Oncogenic Role and Prognostic Value of MicroRNA-937-3p in Patients with Breast Cancer.
Li D, Zhong J, Zhang G, Lin L, Liu Z
OncoTargets and therapy 2019;12:11045-11056
OncoTargets and therapy 2019;12:11045-11056
Osteoglycin (OGN) Inhibits Cell Proliferation and Invasiveness in Breast Cancer via PI3K/Akt/mTOR Signaling Pathway.
Xu T, Zhang R, Dong M, Zhang Z, Li H, Zhan C, Li X
OncoTargets and therapy 2019;12:10639-10650
OncoTargets and therapy 2019;12:10639-10650
Overexpressing CCT6A Contributes To Cancer Cell Growth By Affecting The G1-To-S Phase Transition And Predicts A Negative Prognosis In Hepatocellular Carcinoma.
Zeng G, Wang J, Huang Y, Lian Y, Chen D, Wei H, Lin C, Huang Y
OncoTargets and therapy 2019;12:10427-10439
OncoTargets and therapy 2019;12:10427-10439
miR-140-3p Suppresses Cell Growth And Induces Apoptosis In Colorectal Cancer By Targeting PD-L1.
Jiang W, Li T, Wang J, Jiao R, Shi X, Huang X, Ji G
OncoTargets and therapy 2019;12:10275-10285
OncoTargets and therapy 2019;12:10275-10285
Osteopontin Mediates Cetuximab Resistance via the MAPK Pathway in NSCLC Cells.
Cui J, Wang J, Lin C, Liu J, Zuo W
OncoTargets and therapy 2019;12:10177-10185
OncoTargets and therapy 2019;12:10177-10185
Long noncoding RNA CASC15 predicts unfavorable prognosis and exerts oncogenic functions in non-small cell lung cancer.
Li M, Chen Y, Zhu J, Gao Z, Wang T, Zhou P
American journal of translational research 2019;11(7):4303-4314
American journal of translational research 2019;11(7):4303-4314
MiR-27a-regulated FOXO1 promotes pancreatic ductal adenocarcinoma cell progression by enhancing Wnt/β-catenin signaling activity.
Ling J, Dong X, Wang L, Xue Y, Jia X, Song W, Li Q
American journal of translational research 2019;11(5):3069-3080
American journal of translational research 2019;11(5):3069-3080
Low-molecular-weight fucoidan attenuates bleomycin-induced pulmonary fibrosis: possible role in inhibiting TGF-β1-induced epithelial-mesenchymal transition through ERK pathway.
Wang L, Zhang P, Li X, Zhang Y, Zhan Q, Wang C
American journal of translational research 2019;11(4):2590-2602
American journal of translational research 2019;11(4):2590-2602
Vitamin D retards intervertebral disc degeneration through inactivation of the NF-κB pathway in mice.
Huang H, Cheng S, Zheng T, Ye Y, Ye A, Zhu S, Lin X
American journal of translational research 2019;11(4):2496-2506
American journal of translational research 2019;11(4):2496-2506
Herbacetin treatment remitted LPS induced inhibition of osteoblast differentiation through blocking AKT/NF-κB signaling pathway.
Cai P, Cai T, Li X, Fan L, Chen G, Yu B, Liu T
American journal of translational research 2019;11(2):865-874
American journal of translational research 2019;11(2):865-874
BPTF cooperates with p50 NF-κB to promote COX-2 expression and tumor cell growth in lung cancer.
Dai M, Hu S, Liu CF, Jiang L, Yu W, Li ZL, Guo W, Tang R, Dong CY, Wu TH, Deng WG
American journal of translational research 2019;11(12):7398-7409
American journal of translational research 2019;11(12):7398-7409
Protective effects of Ulinastatin on oxidative stress and inflammation of rat-derived cardiomyocytes H9c2.
Xie X, Li T, Yuan H
American journal of translational research 2019;11(11):7094-7103
American journal of translational research 2019;11(11):7094-7103
A pilot study comparing the genetic molecular biology of gestational and non-gestational choriocarcinoma.
Lazare C, Zhi W, Dai J, Cao C, Sookha RR, Wang L, Meng Y, Gao P, Wu P, Wei J, Hu J, Wu P
American journal of translational research 2019;11(11):7049-7062
American journal of translational research 2019;11(11):7049-7062
HnRNP-F promotes cell proliferation by regulating TPX2 in bladder cancer.
Li F, Su M, Zhao H, Xie W, Cao S, Xu Y, Chen W, Wang L, Hou L, Tan W
American journal of translational research 2019;11(11):7035-7048
American journal of translational research 2019;11(11):7035-7048
UBE2T promotes proliferation via G2/M checkpoint in hepatocellular carcinoma.
Liu LL, Zhu JM, Yu XN, Zhu HR, Shi X, Bilegsaikhan E, Guo HY, Wu J, Shen XZ
Cancer management and research 2019;11:8359-8370
Cancer management and research 2019;11:8359-8370
Overexpression of HOXC6 promotes cell proliferation and migration via MAPK signaling and predicts a poor prognosis in glioblastoma.
Yang P, Kang W, Pan Y, Zhao X, Duan L
Cancer management and research 2019;11:8167-8179
Cancer management and research 2019;11:8167-8179
Upregulation of family with sequence similarity 83 member D expression enhances cell proliferation and motility via activation of Wnt/β-catenin signaling and predicts poor prognosis in gastric cancer.
Wang F, Zhang S, Wei Y, Chen H, Jiao Z, Li Y
Cancer management and research 2019;11:6775-6791
Cancer management and research 2019;11:6775-6791
The β-galactoside α2,6-sialyltranferase 1 (ST6GAL1) inhibits the colorectal cancer metastasis by stabilizing intercellular adhesion molecule-1 via sialylation.
Zhou L, Zhang S, Zou X, Lu J, Yang X, Xu Z, Shan A, Jia W, Liu F, Yan X, Su H, Liang T, Zheng M, Zhang Y, Feng B
Cancer management and research 2019;11:6185-6199
Cancer management and research 2019;11:6185-6199
siPRDX2-elevated DNM3 inhibits the proliferation and metastasis of colon cancer cells via AKT signaling pathway.
Ma Y, Guan L, Han Y, Zhou Y, Li X, Liu Y, Zhang X, Zhang W, Li X, Wang S, Lu W
Cancer management and research 2019;11:5799-5811
Cancer management and research 2019;11:5799-5811
Candidate tumor suppressor gene IRF6 is involved in human breast cancer pathogenesis via modulating PI3K-regulatory subunit PIK3R2 expression.
Xu HF, Huang TJ, Yang Q, Xu L, Lin F, Lang YH, Hu H, Peng LX, Meng DF, Xie YJ, Tan L, Qian CN, Huang BJ
Cancer management and research 2019;11:5557-5572
Cancer management and research 2019;11:5557-5572
Dl-3-n-Butylphthalide Exerts Dopaminergic Neuroprotection Through Inhibition of Neuroinflammation.
Chen Y, Wu T, Li H, Li X, Li Q, Zhu X, Yu M, Kuo SH, Huang F, Wu YC
Frontiers in aging neuroscience 2019;11:44
Frontiers in aging neuroscience 2019;11:44
UNBS5162 and amonafide inhibits tumor progression in human melanoma by the AKT/mTOR pathway.
Ye Y, Huang S, Wu Y
Cancer management and research 2019;11:2339-2348
Cancer management and research 2019;11:2339-2348
The oncogenic role of GNL3 in the progression and metastasis of osteosarcoma.
Li T, Li L, Wu X, Tian K, Wang Y
Cancer management and research 2019;11:2179-2188
Cancer management and research 2019;11:2179-2188
Peptide V3 Inhibits the Growth of Human Hepatocellular Carcinoma by Inhibiting the Ras/Raf/MEK/ERK Signaling Pathway.
Wu D, Li M, Gao Y, Tian W, Li J, Zhang Q, Liu Z, Zheng M, Wang H, Wang J, Teng T, Zhang L, Ji X, Xie Z, Ji A, Li Y
Journal of Cancer 2019;10(7):1693-1706
Journal of Cancer 2019;10(7):1693-1706
Lyn Kinase Promotes the Proliferation of Malignant Melanoma Cells through Inhibition of Apoptosis and Autophagy via the PI3K/Akt Signaling Pathway.
Zhang Q, Meng X, Qin G, Xue X, Dang N
Journal of Cancer 2019;10(5):1197-1208
Journal of Cancer 2019;10(5):1197-1208
High expression of calreticulin indicates poor prognosis and modulates cell migration and invasion via activating Stat3 in nasopharyngeal carcinoma.
Han Y, Liao Q, Wang H, Rao S, Yi P, Tang L, Tian Y, Oyang L, Wang H, Shi Y, Zhou Y
Journal of Cancer 2019;10(22):5460-5468
Journal of Cancer 2019;10(22):5460-5468
The Role of the Tumor Microenvironment in Neuropilin 1-Induced Radiation Resistance in Lung Cancer Cells.
Dong Z, Zhang H, Gong X, Wei W, Lv Y, Chen Z, Wang R, Yi J, Shen Y, Jin S
Journal of Cancer 2019;10(17):4017-4030
Journal of Cancer 2019;10(17):4017-4030
KIAA0101 is a novel transcriptional target of FoxM1 and is involved in the regulation of hepatocellular carcinoma microvascular invasion by regulating epithelial-mesenchymal transition.
Zhang T, Guo J, Gu J, Chen K, Wang Z, Li H, Wang G, Wang J
Journal of Cancer 2019;10(15):3501-3516
Journal of Cancer 2019;10(15):3501-3516
Association of SMUG1 SNPs in Intron Region and Linkage Disequilibrium with Occurrence of Cervical Carcinoma and HPV Infection in Chinese Population.
Ye F, Wang H, Liu J, Cheng Q, Chen X, Chen H
Journal of Cancer 2019;10(1):238-248
Journal of Cancer 2019;10(1):238-248
PINK1/Parkin-Mediated Mitophagy Regulation by Reactive Oxygen Species Alleviates Rocaglamide A-Induced Apoptosis in Pancreatic Cancer Cells.
Zhao C, He R, Shen M, Zhu F, Wang M, Liu Y, Chen H, Li X, Qin R
Frontiers in pharmacology 2019;10:968
Frontiers in pharmacology 2019;10:968
MicroRNA-532-3p Suppresses Malignant Behaviors of Tongue Squamous Cell Carcinoma via Regulating CCR7.
Feng C, So HI, Yin S, Su X, Xu Q, Wang S, Duan W, Zhang E, Sun C, Xu Z
Frontiers in pharmacology 2019;10:940
Frontiers in pharmacology 2019;10:940
ANLN and KDR Are Jointly Prognostic of Breast Cancer Survival and Can Be Modulated for Triple Negative Breast Cancer Control.
Dai X, Mei Y, Chen X, Cai D
Frontiers in genetics 2019;10:790
Frontiers in genetics 2019;10:790
FKN Facilitates HK-2 Cell EMT and Tubulointerstitial Lesions via the Wnt/β-Catenin Pathway in a Murine Model of Lupus Nephritis.
Fu D, Senouthai S, Wang J, You Y
Frontiers in immunology 2019;10:784
Frontiers in immunology 2019;10:784
Emodin Induced SREBP1-Dependent and SREBP1-Independent Apoptosis in Hepatocellular Carcinoma Cells.
Yang N, Li C, Li H, Liu M, Cai X, Cao F, Feng Y, Li M, Wang X
Frontiers in pharmacology 2019;10:709
Frontiers in pharmacology 2019;10:709
Myricetin Attenuated Diabetes-Associated Kidney Injuries and Dysfunction via Regulating Nuclear Factor (Erythroid Derived 2)-Like 2 and Nuclear Factor-κB Signaling.
Yang ZJ, Wang HR, Wang YI, Zhai ZH, Wang LW, Li L, Zhang C, Tang L
Frontiers in pharmacology 2019;10:647
Frontiers in pharmacology 2019;10:647
A Novel α-Galactosidase A Splicing Mutation Predisposes to Fabry Disease.
Li P, Zhang L, Zhao N, Xiong Q, Zhou YA, Wu C, Xiao H
Frontiers in genetics 2019;10:60
Frontiers in genetics 2019;10:60
Sex Dependent Dysregulation of Hepatic Glucose Production in Lean Type 2 Diabetic Rats.
Blesson CS, Schutt A, Chacko S, Marini JC, Mathew PR, Tanchico D, Balakrishnan M, Yallampalli C
Frontiers in endocrinology 2019;10:538
Frontiers in endocrinology 2019;10:538
DNA Sensor IFI204 Contributes to Host Defense Against Staphylococcus aureus Infection in Mice.
Chen W, Yu SX, Zhou FH, Zhang XJ, Gao WY, Li KY, Liu ZZ, Han WY, Yang YJ
Frontiers in immunology 2019;10:474
Frontiers in immunology 2019;10:474
Mechanosensitive Ion Channel Piezo1 Regulates Diet-Induced Adipose Inflammation and Systemic Insulin Resistance.
Zhao C, Sun Q, Tang L, Cao Y, Nourse JL, Pathak MM, Lu X, Yang Q
Frontiers in endocrinology 2019;10:373
Frontiers in endocrinology 2019;10:373
Phosphorylation of Microtubule- Associated Protein 4 Promotes Hypoxic Endothelial Cell Migration and Proliferation.
Zhang J, Li L, Zhang Q, Yang X, Zhang C, Zhang X, Zhang D, Lv Y, Song H, Chen B, Liu Y, Hu J, Huang Y
Frontiers in pharmacology 2019;10:368
Frontiers in pharmacology 2019;10:368
Transient Inhibition of mTORC1 Signaling Ameliorates Irradiation-Induced Liver Damage.
Yang W, Shao L, Zhu S, Li H, Zhang X, Ding C, Wu X, Xu R, Yue M, Tang J, Kuang B, Fan G, Zhu Q, Zeng H
Frontiers in physiology 2019;10:228
Frontiers in physiology 2019;10:228
DDX23, an Evolutionary Conserved dsRNA Sensor, Participates in Innate Antiviral Responses by Pairing With TRIF or MAVS.
Ruan J, Cao Y, Ling T, Li P, Wu S, Peng D, Wang Y, Jia X, Chen S, Xu A, Yuan S
Frontiers in immunology 2019;10:2202
Frontiers in immunology 2019;10:2202
Structural and Functional Characterization of Hermetia illucens Larval Midgut.
Bonelli M, Bruno D, Caccia S, Sgambetterra G, Cappellozza S, Jucker C, Tettamanti G, Casartelli M
Frontiers in physiology 2019;10:204
Frontiers in physiology 2019;10:204
Antiproliferative and Immunoregulatory Effects of Azelaic Acid Against Acute Myeloid Leukemia via the Activation of Notch Signaling Pathway.
Dongdong Z, Jin Y, Yang T, Yang Q, Wu B, Chen Y, Luo Z, Liang L, Liu Y, Xu A, Tong X, Can C, Ding L, Tu H, Tan Y, Jiang H, Liu X, Shen H, Liu L, Pan Y, Wei Y, Zhou F
Frontiers in pharmacology 2019;10:1396
Frontiers in pharmacology 2019;10:1396
Huang-Lian-Jie-Du Decoction Ameliorates Acute Ulcerative Colitis in Mice via Regulating NF-κB and Nrf2 Signaling Pathways and Enhancing Intestinal Barrier Function.
Yuan Z, Yang L, Zhang X, Ji P, Hua Y, Wei Y
Frontiers in pharmacology 2019;10:1354
Frontiers in pharmacology 2019;10:1354
Muscle-Specific Sensitivity to Voluntary Physical Activity and Detraining.
Hyatt JK, Brown EA, Deacon HM, McCall GE
Frontiers in physiology 2019;10:1328
Frontiers in physiology 2019;10:1328
USP37 Promotes Lung Cancer Cell Migration by Stabilizing Snail Protein via Deubiquitination.
Cai J, Li M, Wang X, Li L, Li Q, Hou Z, Jia H, Liu S
Frontiers in genetics 2019;10:1324
Frontiers in genetics 2019;10:1324
Seneca Valley Virus 2C and 3Cpro Induce Apoptosis via Mitochondrion-Mediated Intrinsic Pathway.
Liu T, Li X, Wu M, Qin L, Chen H, Qian P
Frontiers in microbiology 2019;10:1202
Frontiers in microbiology 2019;10:1202
Parental Renovascular Hypertension-Induced Autonomic Dysfunction in Male Offspring Is Improved by Prenatal or Postnatal Treatment With Hydrogen Sulfide.
Guo Q, Feng X, Xue H, Jin S, Teng X, Duan X, Xiao L, Wu Y
Frontiers in physiology 2019;10:1184
Frontiers in physiology 2019;10:1184
Severe Fever With Thrombocytopenia Syndrome Virus-Induced Macrophage Differentiation Is Regulated by miR-146.
Zhang L, Fu Y, Wang H, Guan Y, Zhu W, Guo M, Zheng N, Wu Z
Frontiers in immunology 2019;10:1095
Frontiers in immunology 2019;10:1095
The Therapeutic Effects of Treadmill Exercise on Osteoarthritis in Rats by Inhibiting the HDAC3/NF-KappaB Pathway in vivo and in vitro.
Zhang H, Ji L, Yang Y, Wei Y, Zhang X, Gang Y, Lu J, Bai L
Frontiers in physiology 2019;10:1060
Frontiers in physiology 2019;10:1060
Protective Effects of Dioscin Against Doxorubicin-Induced Hepatotoxicity Via Regulation of Sirt1/FOXO1/NF-κb Signal.
Song S, Chu L, Liang H, Chen J, Liang J, Huang Z, Zhang B, Chen X
Frontiers in pharmacology 2019;10:1030
Frontiers in pharmacology 2019;10:1030
Apigenin Inhibits IL-6 Transcription and Suppresses Esophageal Carcinogenesis.
Qiu JG, Wang L, Liu WJ, Wang JF, Zhao EJ, Zhou FM, Ji XB, Wang LH, Xia ZK, Wang W, Lin MC, Liu LZ, Huang YX, Jiang BH
Frontiers in pharmacology 2019;10:1002
Frontiers in pharmacology 2019;10:1002
Decreased NDRG1 expression is associated with pregnancy loss in mice and attenuates the in vitro decidualization of endometrial stromal cells.
Meng N, Yang Q, He Y, Gu WW, Gu Y, Zhen XX, Wang J, Zhang X, Sun ZG, Wang J
Molecular reproduction and development 2019 Sep;86(9):1210-1223
Molecular reproduction and development 2019 Sep;86(9):1210-1223
Knockdown of SP1/Syncytin1 axis inhibits the proliferation and metastasis through the AKT and ERK1/2 signaling pathways in non-small cell lung cancer.
Li X, Fu Y, Xia X, Zhang X, Xiao K, Zhuang X, Zhang Y
Cancer medicine 2019 Sep;8(12):5750-5759
Cancer medicine 2019 Sep;8(12):5750-5759
HOXA10 induces BCL2 expression, inhibits apoptosis, and promotes cell proliferation in gastric cancer.
Song C, Han Y, Luo H, Qin Z, Chen Z, Liu Y, Lu S, Sun H, Zhou C
Cancer medicine 2019 Sep;8(12):5651-5661
Cancer medicine 2019 Sep;8(12):5651-5661
Telbivudine antagonizes TLR4 to inhibit the epithelial-to-mesenchymal transition in human proximal tubular epithelial cells in vitro.
Chen J, Li D, Luo E
International immunopharmacology 2019 Sep;74:105683
International immunopharmacology 2019 Sep;74:105683
Functional evaluation of a novel GLA causative mutation in Fabry disease.
Li P, Zhang L, Xiong Q, Wang Z, Cui X, Zhou YA, Wang Y, Xiao H, Wu C
Molecular genetics & genomic medicine 2019 Sep;7(9):e864
Molecular genetics & genomic medicine 2019 Sep;7(9):e864
Cholesterol transport through the peroxisome-ER membrane contacts tethered by PI(4,5)P2 and extended synaptotagmins.
Xiao J, Luo J, Hu A, Xiao T, Li M, Kong Z, Jiang L, Zhou Z, Liao Y, Xie C, Chu B, Miao H, Li B, Shi X, Song BL
Science China. Life sciences 2019 Sep;62(9):1117-1135
Science China. Life sciences 2019 Sep;62(9):1117-1135
The interaction between PLEKHG2 and ABL1 suppresses cell growth via the NF-κB signaling pathway in HEK293 cells.
Nishikawa M, Nakano S, Nakao H, Sato K, Sugiyama T, Akao Y, Nagaoka H, Yamakawa H, Nagase T, Ueda H
Cellular signalling 2019 Sep;61:93-107
Cellular signalling 2019 Sep;61:93-107
Seneca Valley virus 2C and 3C inhibit type I interferon production by inducing the degradation of RIG-I.
Wen W, Yin M, Zhang H, Liu T, Chen H, Qian P, Hu J, Li X
Virology 2019 Sep;535:122-129
Virology 2019 Sep;535:122-129
Overexpression of matrix metalloproteinase-9 in breast cancer cell lines remarkably increases the cell malignancy largely via activation of transforming growth factor beta/SMAD signalling.
Dong H, Diao H, Zhao Y, Xu H, Pei S, Gao J, Wang J, Hussain T, Zhao D, Zhou X, Lin D
Cell proliferation 2019 Sep;52(5):e12633
Cell proliferation 2019 Sep;52(5):e12633
Essential role of IκBNS for in vivo CD4+ T-cell activation, proliferation, and Th1-cell differentiation during Listeria monocytogenes infection in mice.
Frentzel S, Katsoulis-Dimitriou K, Jeron A, Schmitz I, Bruder D
European journal of immunology 2019 Sep;49(9):1391-1398
European journal of immunology 2019 Sep;49(9):1391-1398
Transforming growth factor β1 promotes fibroblast-like synoviocytes migration and invasion via TGF-β1/Smad signaling in rheumatoid arthritis.
Zhu D, Zhao J, Lou A, Huang Q, OuYang Q, Zhu J, Fan M, He Y, Ren H, Yang M
Molecular and cellular biochemistry 2019 Sep;459(1-2):141-150
Molecular and cellular biochemistry 2019 Sep;459(1-2):141-150
MiR-212-3p inhibits cell proliferation and promotes apoptosis by targeting nuclear factor IA in bladder cancer.
Wu X, Chen H, Zhang G, Wu J, Zhu W, Gu Y, He YI
Journal of biosciences 2019 Sep;44(4)
Journal of biosciences 2019 Sep;44(4)
Ubiquitin ligase TRIM65 promotes colorectal cancer metastasis by targeting ARHGAP35 for protein degradation.
Chen D, Li Y, Zhang X, Wu H, Wang Q, Cai J, Cui Y, Liu H, Lan P, Wang J, Yang Z, Wang L
Oncogene 2019 Sep;38(37):6429-6444
Oncogene 2019 Sep;38(37):6429-6444
Regional Ischemic Preconditioning Has Clinical Value in Cirrhotic HCC Through MAPK Pathways.
Wang L, Feng L, Rong W, Liu M, Wu F, Yu W, An S, Zhou X, Wu J
Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract 2019 Sep;23(9):1767-1777
Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract 2019 Sep;23(9):1767-1777
Bavachinin exhibits antitumor activity against non‑small cell lung cancer by targeting PPARγ.
Ge LN, Yan L, Li C, Cheng K
Molecular medicine reports 2019 Sep;20(3):2805-2811
Molecular medicine reports 2019 Sep;20(3):2805-2811
Upregulation of EPS8L3 is associated with tumorigenesis and poor prognosis in patients with liver cancer.
Li P, Hu T, Wang H, Tang Y, Ma Y, Wang X, Xu Y, Chen G
Molecular medicine reports 2019 Sep;20(3):2493-2499
Molecular medicine reports 2019 Sep;20(3):2493-2499
Cancer associated fibroblasts are distinguishable from peri-tumor fibroblasts by biological characteristics in TSCC.
Ba P, Zhang X, Yu M, Li L, Duan X, Wang M, Lv S, Fu G, Yang P, Yang C, Sun Q
Oncology letters 2019 Sep;18(3):2484-2490
Oncology letters 2019 Sep;18(3):2484-2490
Probiotic effect on Helicobacter pylori attachment and inhibition of inflammation in human gastric epithelial cells.
Song H, Zhou L, Liu D, Ge L, Li Y
Experimental and therapeutic medicine 2019 Sep;18(3):1551-1562
Experimental and therapeutic medicine 2019 Sep;18(3):1551-1562
Inhibition of polycomb repressor complex 2 ameliorates neointimal hyperplasia by suppressing trimethylation of H3K27 in vascular smooth muscle cells.
Liang J, Li Q, Cai W, Zhang X, Yang B, Li X, Jiang S, Tian S, Zhang K, Song H, Ai D, Zhang X, Wang C, Zhu Y
British journal of pharmacology 2019 Sep;176(17):3206-3219
British journal of pharmacology 2019 Sep;176(17):3206-3219
Functional daidzein enhances the anticancer effect of topotecan and reverses BCRP-mediated drug resistance in breast cancer.
Guo J, Wang Q, Zhang Y, Sun W, Zhang S, Li Y, Wang J, Bao Y
Pharmacological research 2019 Sep;147:104387
Pharmacological research 2019 Sep;147:104387
SARI attenuates colon inflammation by promoting STAT1 degradation in intestinal epithelial cells.
Dai L, Liu Y, Cheng L, Wang H, Lin Y, Shi G, Dong Z, Li J, Fan P, Wang Q, Su X, Zhang S, Yang Y, Hu X, Huang W, Zhou Z, Yu D, Probert C, Wei Y, Deng H
Mucosal immunology 2019 Sep;12(5):1130-1140
Mucosal immunology 2019 Sep;12(5):1130-1140
In vitro effect of Pannexin 1 channel on the invasion and migration of I-10 testicular cancer cells via ERK1/2 signaling pathway.
Liu H, Yuan M, Yao Y, Wu D, Dong S, Tong X
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Sep;117:109090
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Sep;117:109090
Treatment with andrographolide sulfonate provides additional benefits to imipenem in a mouse model of Klebsiella pneumoniae pneumonia.
Zhang G, Jiang C, Xie N, Xu Y, Liu L, Liu N
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Sep;117:109065
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Sep;117:109065
circMTO1 promotes tumorigenesis and chemoresistance of cervical cancer via regulating miR-6893.
Chen M, Ai G, Zhou J, Mao W, Li H, Guo J
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Sep;117:109064
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Sep;117:109064
Kinesin family member C1 accelerates bladder cancer cell proliferation and induces epithelial-mesenchymal transition via Akt/GSK3β signaling.
Xiao KH, Teng K, Ye YL, Tan L, Chen MK, Liang HT, Feng ZH, Duan JL, Deng MH, Wei WS, Luo JH, Qin ZK, Xie D
Cancer science 2019 Sep;110(9):2822-2833
Cancer science 2019 Sep;110(9):2822-2833
Angiopoietin-Like Protein 4 (ANGPTL4) Induces Retinal Pigment Epithelial Barrier Breakdown by Activating Signal Transducer and Activator of Transcription 3 (STAT3): Evidence from ARPE-19 Cells Under Hypoxic Condition and Diabetic Rats.
Yang X, Cao J, Du Y, Gong Q, Cheng Y, Su G
Medical science monitor : international medical journal of experimental and clinical research 2019 Sep 8;25:6742-6754
Medical science monitor : international medical journal of experimental and clinical research 2019 Sep 8;25:6742-6754
De novo synthesis of serine and glycine fuels purine nucleotide biosynthesis in human lung cancer tissues.
Fan TWM, Bruntz RC, Yang Y, Song H, Chernyavskaya Y, Deng P, Zhang Y, Shah PP, Beverly LJ, Qi Z, Mahan AL, Higashi RM, Dang CV, Lane AN
The Journal of biological chemistry 2019 Sep 6;294(36):13464-13477
The Journal of biological chemistry 2019 Sep 6;294(36):13464-13477
lncRNA NR_038323 Suppresses Renal Fibrosis in Diabetic Nephropathy by Targeting the miR-324-3p/DUSP1 Axis.
Ge Y, Wang J, Wu D, Zhou Y, Qiu S, Chen J, Zhu X, Xiang X, Li H, Zhang D
Molecular therapy. Nucleic acids 2019 Sep 6;17:741-753
Molecular therapy. Nucleic acids 2019 Sep 6;17:741-753
Myosin II isoforms play distinct roles in adherens junction biogenesis.
Heuzé ML, Sankara Narayana GHN, D'Alessandro J, Cellerin V, Dang T, Williams DS, Van Hest JC, Marcq P, Mège RM, Ladoux B
eLife 2019 Sep 5;8
eLife 2019 Sep 5;8
CD36 inhibits β-catenin/c-myc-mediated glycolysis through ubiquitination of GPC4 to repress colorectal tumorigenesis.
Fang Y, Shen ZY, Zhan YZ, Feng XC, Chen KL, Li YS, Deng HJ, Pan SM, Wu DH, Ding Y
Nature communications 2019 Sep 4;10(1):3981
Nature communications 2019 Sep 4;10(1):3981
MiR-532-3p suppresses colorectal cancer progression by disrupting the ETS1/TGM2 axis-mediated Wnt/β-catenin signaling.
Gu C, Cai J, Xu Z, Zhou S, Ye L, Yan Q, Zhang Y, Fang Y, Liu Y, Tu C, Wang X, He J, Li Q, Han L, Lin X, Li A, Liu S
Cell death & disease 2019 Sep 30;10(10):739
Cell death & disease 2019 Sep 30;10(10):739
Ubiquitin ligase TRIM71 suppresses ovarian tumorigenesis by degrading mutant p53.
Chen Y, Hao Q, Wang J, Li J, Huang C, Zhang Y, Wu X, Lu H, Zhou X
Cell death & disease 2019 Sep 30;10(10):737
Cell death & disease 2019 Sep 30;10(10):737
Inhibition of MCF-7 breast cancer cell proliferation by a synthetic peptide derived from the C-terminal sequence of Orai channel.
Li S, Yao M, Niu C, Liu D, Tang Z, Gu C, Zhao H, Ke J, Wu S, Wang X, Wu F
Biochemical and biophysical research communications 2019 Sep 3;516(4):1066-1072
Biochemical and biophysical research communications 2019 Sep 3;516(4):1066-1072
Ribavirin Induces Polyamine Depletion via Nucleotide Depletion to Limit Virus Replication.
Tate PM, Mastrodomenico V, Mounce BC
Cell reports 2019 Sep 3;28(10):2620-2633.e4
Cell reports 2019 Sep 3;28(10):2620-2633.e4
microRNA arm-imbalance in part from complementary targets mediated decay promotes gastric cancer progression.
Zhang Z, Pi J, Zou D, Wang X, Xu J, Yu S, Zhang T, Li F, Zhang X, Zhao H, Wang F, Wang D, Ma Y, Yu J
Nature communications 2019 Sep 27;10(1):4397
Nature communications 2019 Sep 27;10(1):4397
NRF2-dependent gene expression promotes ciliogenesis and Hedgehog signaling.
Martin-Hurtado A, Martin-Morales R, Robledinos-Antón N, Blanco R, Palacios-Blanco I, Lastres-Becker I, Cuadrado A, Garcia-Gonzalo FR
Scientific reports 2019 Sep 25;9(1):13896
Scientific reports 2019 Sep 25;9(1):13896
Targeting the IL-1β/IL-1Ra pathways for the aggregation of human islet amyloid polypeptide in an ex vivo organ culture system of the intervertebral disc.
Wu X, Liao Z, Wang K, Hua W, Liu X, Song Y, Zhang Y, Yang S, Yang C
Experimental & molecular medicine 2019 Sep 25;51(9):1-16
Experimental & molecular medicine 2019 Sep 25;51(9):1-16
Modulation of M2 macrophage polarization by the crosstalk between Stat6 and Trim24.
Yu T, Gan S, Zhu Q, Dai D, Li N, Wang H, Chen X, Hou D, Wang Y, Pan Q, Xu J, Zhang X, Liu J, Pei S, Peng C, Wu P, Romano S, Mao C, Huang M, Zhu X, Shen K, Qin J, Xiao Y
Nature communications 2019 Sep 25;10(1):4353
Nature communications 2019 Sep 25;10(1):4353
OPA1 overexpression ameliorates mitochondrial cristae remodeling, mitochondrial dysfunction, and neuronal apoptosis in prion diseases.
Wu W, Zhao D, Shah SZA, Zhang X, Lai M, Yang D, Wu X, Guan Z, Li J, Zhao H, Li W, Gao H, Zhou X, Qiao J, Yang L
Cell death & disease 2019 Sep 24;10(10):710
Cell death & disease 2019 Sep 24;10(10):710
Retromer and TBC1D5 maintain late endosomal RAB7 domains to enable amino acid-induced mTORC1 signaling.
Kvainickas A, Nägele H, Qi W, Dokládal L, Jimenez-Orgaz A, Stehl L, Gangurde D, Zhao Q, Hu Z, Dengjel J, De Virgilio C, Baumeister R, Steinberg F
The Journal of cell biology 2019 Sep 2;218(9):3019-3038
The Journal of cell biology 2019 Sep 2;218(9):3019-3038
Recurrent GNAQ mutation encoding T96S in natural killer/T cell lymphoma.
Li Z, Zhang X, Xue W, Zhang Y, Li C, Song Y, Mei M, Lu L, Wang Y, Zhou Z, Jin M, Bian Y, Zhang L, Wang X, Li L, Li X, Fu X, Sun Z, Wu J, Nan F, Chang Y, Yan J, Yu H, Feng X, Wang G, Zhang D, Fu X, Zhang Y, Young KH, Li W, Zhang M
Nature communications 2019 Sep 16;10(1):4209
Nature communications 2019 Sep 16;10(1):4209
Up-regulated cathepsin C induces macrophage M1 polarization through FAK-triggered p38 MAPK/NF-κB pathway.
Alam S, Liu Q, Liu S, Liu Y, Zhang Y, Yang X, Liu G, Fan K, Ma J
Experimental cell research 2019 Sep 15;382(2):111472
Experimental cell research 2019 Sep 15;382(2):111472
Altered bile acid composition and disposition in a mouse model of non-alcoholic steatohepatitis.
Suga T, Yamaguchi H, Ogura J, Shoji S, Maekawa M, Mano N
Toxicology and applied pharmacology 2019 Sep 15;379:114664
Toxicology and applied pharmacology 2019 Sep 15;379:114664
Extensive disruption of protein interactions by genetic variants across the allele frequency spectrum in human populations.
Fragoza R, Das J, Wierbowski SD, Liang J, Tran TN, Liang S, Beltran JF, Rivera-Erick CA, Ye K, Wang TY, Yao L, Mort M, Stenson PD, Cooper DN, Wei X, Keinan A, Schimenti JC, Clark AG, Yu H
Nature communications 2019 Sep 12;10(1):4141
Nature communications 2019 Sep 12;10(1):4141
Near-Infrared Light-Sensitive Nano Neuro-Immune Blocker Capsule Relieves Pain and Enhances the Innate Immune Response for Necrotizing Infection.
Zhao Q, Wang J, Yin C, Zhang P, Zhang J, Shi M, Shen K, Xiao Y, Zhao Y, Yang X, Zhang Y
Nano letters 2019 Sep 11;19(9):5904-5914
Nano letters 2019 Sep 11;19(9):5904-5914
Transforming growth factor (TGF)-β1-induced miR-133a inhibits myofibroblast differentiation and pulmonary fibrosis.
Wei P, Xie Y, Abel PW, Huang Y, Ma Q, Li L, Hao J, Wolff DW, Wei T, Tu Y
Cell death & disease 2019 Sep 11;10(9):670
Cell death & disease 2019 Sep 11;10(9):670
miR-146a attenuates apoptosis and modulates autophagy by targeting TAF9b/P53 pathway in doxorubicin-induced cardiotoxicity.
Pan JA, Tang Y, Yu JY, Zhang H, Zhang JF, Wang CQ, Gu J
Cell death & disease 2019 Sep 11;10(9):668
Cell death & disease 2019 Sep 11;10(9):668
Exosomal transfer of miR-501 confers doxorubicin resistance and tumorigenesis via targeting of BLID in gastric cancer.
Liu X, Lu Y, Xu Y, Hou S, Huang J, Wang B, Zhao J, Xia S, Fan S, Yu X, Du Y, Hou L, Li Z, Ding Z, An S, Huang B, Li L, Tang J, Ju J, Guan H, Song B
Cancer letters 2019 Sep 10;459:122-134
Cancer letters 2019 Sep 10;459:122-134
Tributyltin exposure disturbs hepatic glucose metabolism in male mice.
Xu J, Ou K, Chen C, Li B, Guo J, Zuo Z, Wang C
Toxicology 2019 Sep 1;425:152242
Toxicology 2019 Sep 1;425:152242
Chronic administration of diethylnitrosamine to induce hepatocarcinogenesis and to evaluate its synergistic effect with other hepatotoxins in mice.
Fuentes-Hernández S, Alarcón-Sánchez BR, Guerrero-Escalera D, Montes-Aparicio AV, Castro-Gil MP, Idelfonso-García OG, Rosas-Madrigal S, Aparicio-Bautista DI, Pérez-Hernández JL, Reyes-Gordillo K, Lakshman MR, Vásquez-Garzón VR, Baltiérrez-Hoyos R, López-González ML, Sierra-Santoyo A, Villa-Treviño S, Pérez-Carreón JI, Arellanes-Robledo J
Toxicology and applied pharmacology 2019 Sep 1;378:114611
Toxicology and applied pharmacology 2019 Sep 1;378:114611
Characterization of a novel separase-interacting protein and candidate new securin, Eip1p, in the fungal pathogen Candida albicans.
Sparapani S, Bachewich C
Molecular biology of the cell 2019 Sep 1;30(19):2469-2489
Molecular biology of the cell 2019 Sep 1;30(19):2469-2489
The estrogen-regulated lncRNA H19/miR-216a-5p axis alters stromal cell invasion and migration via ACTA2 in endometriosis.
Xu Z, Zhang L, Yu Q, Zhang Y, Yan L, Chen ZJ
Molecular human reproduction 2019 Sep 1;25(9):550-561
Molecular human reproduction 2019 Sep 1;25(9):550-561
Inhibiting effect of microRNA-187-3p on osteogenic differentiation of osteoblast precursor cells by suppressing cannabinoid receptor type 2.
Xu A, Yang Y, Shao Y, Wu M, Sun Y
Differentiation; research in biological diversity 2019 Sep - Oct;109:9-15
Differentiation; research in biological diversity 2019 Sep - Oct;109:9-15
Increased miR-214 expression suppresses cell migration and proliferation in Hirschsprung disease by interacting with PLAGL2.
Wu L, Yuan W, Chen J, Zhou Z, Shu Y, Ji J, Liu Z, Tang Q, Zhang X, Shu X
Pediatric research 2019 Oct;86(4):460-470
Pediatric research 2019 Oct;86(4):460-470
Baicalein and baicalin promote antitumor immunity by suppressing PD-L1 expression in hepatocellular carcinoma cells.
Ke M, Zhang Z, Xu B, Zhao S, Ding Y, Wu X, Wu R, Lv Y, Dong J
International immunopharmacology 2019 Oct;75:105824
International immunopharmacology 2019 Oct;75:105824
Potential role of M2 macrophage polarization in ventilator-induced lung fibrosis.
Wang L, Zhang Y, Zhang N, Xia J, Zhan Q, Wang C
International immunopharmacology 2019 Oct;75:105795
International immunopharmacology 2019 Oct;75:105795
MiR-92a regulates endothelial progenitor cells (EPCs) by targeting GDF11 via activate SMAD2/3/FAK/Akt/eNOS pathway.
Huang HT, Liu ZC, Wu KQ, Gu SR, Lu TC, Zhong CJ, Zhou YX
Annals of translational medicine 2019 Oct;7(20):563
Annals of translational medicine 2019 Oct;7(20):563
Direct Amplification of Tissue Factor:Factor VIIa Procoagulant Activity by Bile Acids Drives Intrahepatic Coagulation.
Baker KS, Kopec AK, Pant A, Poole LG, Cline-Fedewa H, Ivkovich D, Olyaee M, Woolbright BL, Miszta A, Jaeschke H, Wolberg AS, Luyendyk JP
Arteriosclerosis, thrombosis, and vascular biology 2019 Oct;39(10):2038-2048
Arteriosclerosis, thrombosis, and vascular biology 2019 Oct;39(10):2038-2048
LINC00346 promotes pancreatic cancer progression through the CTCF-mediated Myc transcription.
Peng WX, He RZ, Zhang Z, Yang L, Mo YY
Oncogene 2019 Oct;38(41):6770-6780
Oncogene 2019 Oct;38(41):6770-6780
HBx regulates transcription factor PAX8 stabilization to promote the progression of hepatocellular carcinoma.
Wang J, Li N, Huang ZB, Fu S, Yu SM, Fu YM, Zhou PC, Chen RC, Zhou RR, Huang Y, Hu XW, Fan XG
Oncogene 2019 Oct;38(40):6696-6710
Oncogene 2019 Oct;38(40):6696-6710
Antioxidant activity of Coridius chinensis extracts on manganese-induced testicular damage in rats.
Liu Q, Cen C, Fu H, Wang F, Wang Y, Xu T, Hou X
Environmental toxicology 2019 Oct;34(10):1067-1073
Environmental toxicology 2019 Oct;34(10):1067-1073
Genistein inhibits nasopharyngeal cancer stem cells through sonic hedgehog signaling.
Zhang Q, Cao WS, Wang XQ, Zhang M, Lu XM, Chen JQ, Chen Y, Ge MM, Zhong CY, Han HY
Phytotherapy research : PTR 2019 Oct;33(10):2783-2791
Phytotherapy research : PTR 2019 Oct;33(10):2783-2791
MiR-100 suppresses inflammatory activation of microglia and neuronal apoptosis following spinal cord injury via TLR4/NF-κB pathway.
Li XH, Fu NS, Xing ZM
European review for medical and pharmacological sciences 2019 Oct;23(20):8713-8720
European review for medical and pharmacological sciences 2019 Oct;23(20):8713-8720
miR-29a promotes pathological cardiac hypertrophy by targeting the PTEN/AKT/mTOR signalling pathway and suppressing autophagy.
Shi JY, Chen C, Xu X, Lu Q
Acta physiologica (Oxford, England) 2019 Oct;227(2):e13323
Acta physiologica (Oxford, England) 2019 Oct;227(2):e13323
Silencing lncRNA SNHG6 suppresses proliferation and invasion of breast cancer cells through miR-26a/VASP axis.
Li K, Ma YB, Tian YH, Xu XL, Gao Y, He YQ, Pan WT, Zhang JW, He CJ, Wei L
Pathology, research and practice 2019 Oct;215(10):152575
Pathology, research and practice 2019 Oct;215(10):152575
NKAP functions as an oncogene in Ewing sarcoma cells partly through the AKT signaling pathway.
Li F, Wu JT, Wang PF, Qu LZ
Experimental and therapeutic medicine 2019 Oct;18(4):3037-3045
Experimental and therapeutic medicine 2019 Oct;18(4):3037-3045
GSK343 induces autophagy and downregulates the AKT/mTOR signaling pathway in pancreatic cancer cells.
Xu H, Zhang L, Qian X, Zhou X, Yan Y, Zhou J, Ge W, Albahde M, Wang W
Experimental and therapeutic medicine 2019 Oct;18(4):2608-2616
Experimental and therapeutic medicine 2019 Oct;18(4):2608-2616
Ginsenoside Rg5 induces G2/M phase arrest, apoptosis and autophagy via regulating ROS-mediated MAPK pathways against human gastric cancer.
Liu Y, Fan D
Biochemical pharmacology 2019 Oct;168:285-304
Biochemical pharmacology 2019 Oct;168:285-304
Hyperoside protects against heart failure-induced liver fibrosis in rats.
Guo X, Zhu C, Liu X, Ge Y, Jiang X, Zhao W
Acta histochemica 2019 Oct;121(7):804-811
Acta histochemica 2019 Oct;121(7):804-811
LXRα-mediated downregulation of EGFR suppress colorectal cancer cell proliferation.
Liang X, Cao Y, Xiang S, Xiang Z
Journal of cellular biochemistry 2019 Oct;120(10):17391-17404
Journal of cellular biochemistry 2019 Oct;120(10):17391-17404
LMX1B involved in the radioresistance, proliferation and migration of esophageal cancer cells.
Zang C, Zhao F, Pu Y
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Oct;118:109358
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Oct;118:109358
Magnesium lithospermate B attenuates renal injury in 5/6 renal ablation/infarction rats by mitochondrial pathway of apoptosis.
Wang M, Yang L, Yang J, Zhou Y, Wang C
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Oct;118:109316
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Oct;118:109316
ACT001, a novel PAI-1 inhibitor, exerts synergistic effects in combination with cisplatin by inhibiting PI3K/AKT pathway in glioma.
Xi X, Liu N, Wang Q, Chu Y, Yin Z, Ding Y, Lu Y
Cell death & disease 2019 Oct 7;10(10):757
Cell death & disease 2019 Oct 7;10(10):757
Strong anion exchange-mediated phosphoproteomics reveals extensive human non-canonical phosphorylation.
Hardman G, Perkins S, Brownridge PJ, Clarke CJ, Byrne DP, Campbell AE, Kalyuzhnyy A, Myall A, Eyers PA, Jones AR, Eyers CE
The EMBO journal 2019 Oct 4;38(21):e100847
The EMBO journal 2019 Oct 4;38(21):e100847
Cichorium intybus L. Extract Suppresses Experimental Gout by Inhibiting the NF-κB and NLRP3 Signaling Pathways.
Wang Y, Lin Z, Zhang B, Jiang Z, Guo F, Yang T
International journal of molecular sciences 2019 Oct 4;20(19)
International journal of molecular sciences 2019 Oct 4;20(19)
Improvement of Mitochondrial Activity and Fibrosis by Resveratrol Treatment in Mice with Schistosoma japonicum Infection.
Chen TT, Peng S, Wang Y, Hu Y, Shen Y, Xu Y, Yin J, Liu C, Cao J
Biomolecules 2019 Oct 25;9(11)
Biomolecules 2019 Oct 25;9(11)
Activated spinal astrocytes contribute to the later phase of carrageenan-induced prostatitis pain.
Deng GC, Lu M, Zhao YY, Yuan Y, Chen G
Journal of neuroinflammation 2019 Oct 25;16(1):189
Journal of neuroinflammation 2019 Oct 25;16(1):189
YTHDF1 links hypoxia adaptation and non-small cell lung cancer progression.
Shi Y, Fan S, Wu M, Zuo Z, Li X, Jiang L, Shen Q, Xu P, Zeng L, Zhou Y, Huang Y, Yang Z, Zhou J, Gao J, Zhou H, Xu S, Ji H, Shi P, Wu DD, Yang C, Chen Y
Nature communications 2019 Oct 25;10(1):4892
Nature communications 2019 Oct 25;10(1):4892
MicroRNA-29a Suppresses CD36 to Ameliorate High Fat Diet-Induced Steatohepatitis and Liver Fibrosis in Mice.
Lin HY, Wang FS, Yang YL, Huang YH
Cells 2019 Oct 22;8(10)
Cells 2019 Oct 22;8(10)
The protective effect of Phellinus linteus decoction on podocyte injury in the kidney of FSGS rats.
Wan F, Yang RC, Shi YP, Tang YW, Tang XL, Zhu XL, Li YG, Wang YJ
BMC complementary and alternative medicine 2019 Oct 21;19(1):272
BMC complementary and alternative medicine 2019 Oct 21;19(1):272
Systematically characterize the clinical and biological significances of 1p19q genes in 1p/19q non-codeletion glioma.
Chai RC, Zhang KN, Chang YZ, Wu F, Liu YQ, Zhao Z, Wang KY, Chang YH, Jiang T, Wang YZ
Carcinogenesis 2019 Oct 16;40(10):1229-1239
Carcinogenesis 2019 Oct 16;40(10):1229-1239
N6-methyladenosine modification of circNSUN2 facilitates cytoplasmic export and stabilizes HMGA2 to promote colorectal liver metastasis.
Chen RX, Chen X, Xia LP, Zhang JX, Pan ZZ, Ma XD, Han K, Chen JW, Judde JG, Deas O, Wang F, Ma NF, Guan X, Yun JP, Wang FW, Xu RH, Dan Xie
Nature communications 2019 Oct 16;10(1):4695
Nature communications 2019 Oct 16;10(1):4695
Exosomal and extracellular HMGB1 have opposite effects on SASH1 expression in rat astrocytes and glioma C6 cells.
Ma C, Chen H, Zhang S, Yan Y, Wu R, Wang Y, Liu Y, Yang L, Liu M
Biochemical and biophysical research communications 2019 Oct 15;518(2):325-330
Biochemical and biophysical research communications 2019 Oct 15;518(2):325-330
Bromodomain-containing protein 4 contributes to renal fibrosis through the induction of epithelial-mesenchymal transition.
Wang X, Zhou Y, Peng Y, Huang T, Xia F, Yang T, Duan Q, Zhang W
Experimental cell research 2019 Oct 15;383(2):111507
Experimental cell research 2019 Oct 15;383(2):111507
Human Umbilical Cord-Derived Mesenchymal Stem Cells Relieve Hind Limb Ischemia by Promoting Angiogenesis in Mice.
Wang Z, Zheng L, Lian C, Qi Y, Li W, Wang S
Stem cells and development 2019 Oct 15;28(20):1384-1397
Stem cells and development 2019 Oct 15;28(20):1384-1397
Dystroglycan is involved in the activation of ERK pathway inducing the change of AQP4 expression in scratch-injured astrocytes.
Zhang G, Ma P, Wan S, Xu J, Yang M, Qiu G, Zhuo F, Xu S, Huo J, Ju Y, Liu H
Brain research 2019 Oct 15;1721:146347
Brain research 2019 Oct 15;1721:146347
Endothelial cell pyroptosis plays an important role in Kawasaki disease via HMGB1/RAGE/cathespin B signaling pathway and NLRP3 inflammasome activation.
Jia C, Zhang J, Chen H, Zhuge Y, Chen H, Qian F, Zhou K, Niu C, Wang F, Qiu H, Wang Z, Xiao J, Rong X, Chu M
Cell death & disease 2019 Oct 14;10(10):778
Cell death & disease 2019 Oct 14;10(10):778
A circular RNA from APC inhibits the proliferation of diffuse large B-cell lymphoma by inactivating Wnt/β-catenin signaling via interacting with TET1 and miR-888.
Hu Y, Zhao Y, Shi C, Ren P, Wei B, Guo Y, Ma J
Aging 2019 Oct 13;11(19):8068-8084
Aging 2019 Oct 13;11(19):8068-8084
Polyphenol-Rich Extracts from Toona sinensis Bark and Fruit Ameliorate Free Fatty Acid-Induced Lipogenesis through AMPK and LC3 Pathways.
Chen YC, Chen HJ, Huang BM, Chen YC, Chang CF
Journal of clinical medicine 2019 Oct 11;8(10)
Journal of clinical medicine 2019 Oct 11;8(10)
TMEM18 inhibits osteogenic differentiation of rat bone marrow-derived mesenchymal stem cells by inactivating β-catenin.
Zhang Y, Wang H, Yin T, Liu Y, Zhou W, Fan X, Wu L, Song C, Shao J, Yang T
Experimental cell research 2019 Oct 1;383(1):111491
Experimental cell research 2019 Oct 1;383(1):111491
Genetic loss of Gas6/Mer pathway attenuates silica-induced lung inflammation and fibrosis in mice.
Li W, Xie L, Ma J, Yang M, Wang B, Xu Y, Fan L, Mu G, Shi T, Chen W
Toxicology letters 2019 Oct 1;313:178-187
Toxicology letters 2019 Oct 1;313:178-187
Serum miR-221-3p as a new potential biomarker for depressed mood in perioperative patients.
Feng J, Wang M, Li M, Yang J, Jia J, Liu L, Zhou J, Zhang C, Wang X
Brain research 2019 Oct 1;1720:146296
Brain research 2019 Oct 1;1720:146296
Prolonged neutrophil retention in the wound impairs zebrafish heart regeneration after cryoinjury.
Xu S, Xie F, Tian L, Manno SH, Manno FAM 3rd, Cheng SH
Fish & shellfish immunology 2019 Nov;94:447-454
Fish & shellfish immunology 2019 Nov;94:447-454
lncRNA ABHD11-AS1, regulated by the EGFR pathway, contributes to the ovarian cancer tumorigenesis by epigenetically suppressing TIMP2.
Zeng XY, Jiang XY, Yong JH, Xie H, Yuan J, Zeng D, Dou YY, Xiao SS
Cancer medicine 2019 Nov;8(16):7074-7085
Cancer medicine 2019 Nov;8(16):7074-7085
Combined MEK inhibition and tumor-associated macrophages depletion suppresses tumor growth in a triple-negative breast cancer mouse model.
Zhang Q, Le K, Xu M, Zhou J, Xiao Y, Yang W, Jiang Y, Xi Z, Huang T
International immunopharmacology 2019 Nov;76:105864
International immunopharmacology 2019 Nov;76:105864
Role of miR-214 in regulation of β-catenin and the malignant phenotype of melanoma.
Prabhakar K, Rodrίguez CI, Jayanthy AS, Mikheil DM, Bhasker AI, Perera RJ, Setaluri V
Molecular carcinogenesis 2019 Nov;58(11):1974-1984
Molecular carcinogenesis 2019 Nov;58(11):1974-1984
Allele-selective lowering of mutant HTT protein by HTT-LC3 linker compounds.
Li Z, Wang C, Wang Z, Zhu C, Li J, Sha T, Ma L, Gao C, Yang Y, Sun Y, Wang J, Sun X, Lu C, Difiglia M, Mei Y, Ding C, Luo S, Dang Y, Ding Y, Fei Y, Lu B
Nature 2019 Nov;575(7781):203-209
Nature 2019 Nov;575(7781):203-209
Structural characterization and biological function of bivalent binding of CD2AP to intrinsically disordered domain of chikungunya virus nsP3 protein.
Agback P, Dominguez F, Pustovalova Y, Lukash T, Shiliaev N, Orekhov VY, Frolov I, Agback T, Frolova EI
Virology 2019 Nov;537:130-142
Virology 2019 Nov;537:130-142
Upregulated PDK4 expression is a sensitive marker of increased fatty acid oxidation.
Pettersen IKN, Tusubira D, Ashrafi H, Dyrstad SE, Hansen L, Liu XZ, Nilsson LIH, Løvsletten NG, Berge K, Wergedahl H, Bjørndal B, Fluge Ø, Bruland O, Rustan AC, Halberg N, Røsland GV, Berge RK, Tronstad KJ
Mitochondrion 2019 Nov;49:97-110
Mitochondrion 2019 Nov;49:97-110
Dehydrogenase/reductase SDR family member 2 silencing sensitizes an oxaliplatin‑resistant cell line to oxaliplatin by inhibiting excision repair cross‑complementing group 1 protein expression.
Li JM, Jiang GM, Zhao L, Yang F, Yuan WQ, Wang H, Luo YQ
Oncology reports 2019 Nov;42(5):1725-1734
Oncology reports 2019 Nov;42(5):1725-1734
KDELR2 Promotes Glioblastoma Tumorigenesis Targeted by HIF1a via mTOR Signaling Pathway.
Liao Z, She C, Ma L, Sun Z, Li P, Zhang X, Wang P, Li W
Cellular and molecular neurobiology 2019 Nov;39(8):1207-1215
Cellular and molecular neurobiology 2019 Nov;39(8):1207-1215
The digestive system of the adult Hermetia illucens (Diptera: Stratiomyidae): morphological features and functional properties.
Bruno D, Bonelli M, Cadamuro AG, Reguzzoni M, Grimaldi A, Casartelli M, Tettamanti G
Cell and tissue research 2019 Nov;378(2):221-238
Cell and tissue research 2019 Nov;378(2):221-238
The protective effect of lithocholic acid on the intestinal epithelial barrier is mediated by the vitamin D receptor via a SIRT1/Nrf2 and NF-κB dependent mechanism in Caco-2 cells.
Yao B, He J, Yin X, Shi Y, Wan J, Tian Z
Toxicology letters 2019 Nov;316:109-118
Toxicology letters 2019 Nov;316:109-118
Transcription factor 7-like 2-associated signaling mechanism in regulating cementum generation by the NF-κB pathway.
Zhao Z, Dai J, Yin C, Wang X, Wang J, Jia X, Zhao Q, Fu H, Zhang Y, Xia H
Journal of cellular physiology 2019 Nov;234(11):20790-20800
Journal of cellular physiology 2019 Nov;234(11):20790-20800
EphA8 acts as an oncogene and contributes to poor prognosis in gastric cancer via regulation of ADAM10.
Wang Y, Zhou N, Li P, Wu H, Wang Q, Gao X, Wang X, Huang J
Journal of cellular physiology 2019 Nov;234(11):20408-20419
Journal of cellular physiology 2019 Nov;234(11):20408-20419
The miR-27a-3p/USP25 axis participates in the pathogenesis of recurrent miscarriage by inhibiting trophoblast migration and invasion.
Ding J, Cheng Y, Zhang Y, Liao S, Yin T, Yang J
Journal of cellular physiology 2019 Nov;234(11):19951-19963
Journal of cellular physiology 2019 Nov;234(11):19951-19963
GSK-3β inhibition protects the rat heart from the lipopolysaccharide-induced inflammation injury via suppressing FOXO3A activity.
Li Z, Zhu H, Liu C, Wang Y, Wang D, Liu H, Cao W, Hu Y, Lin Q, Tong C, Lu M, Sachinidis A, Li L, Peng L
Journal of cellular and molecular medicine 2019 Nov;23(11):7796-7809
Journal of cellular and molecular medicine 2019 Nov;23(11):7796-7809
Long non-coding RNA cardiac hypertrophy-associated regulator governs cardiac hypertrophy via regulating miR-20b and the downstream PTEN/AKT pathway.
Zhang M, Jiang Y, Guo X, Zhang B, Wu J, Sun J, Liang H, Shan H, Zhang Y, Liu J, Wang Y, Wang L, Zhang R, Yang B, Xu C
Journal of cellular and molecular medicine 2019 Nov;23(11):7685-7698
Journal of cellular and molecular medicine 2019 Nov;23(11):7685-7698
TMPO-AS1 promotes cervical cancer progression by upregulating RAB14 via sponging miR-577.
Yang J, Liang B, Hou S
The journal of gene medicine 2019 Nov;21(11):e3125
The journal of gene medicine 2019 Nov;21(11):e3125
Knockdown of long noncoding RNA DLEU1 suppresses the progression of renal cell carcinoma by downregulating the Akt pathway.
Yue G, Chen C, Bai L, Wang G, Huang Y, Wang Y, Cui H, Xiao Y
Molecular medicine reports 2019 Nov;20(5):4551-4557
Molecular medicine reports 2019 Nov;20(5):4551-4557
Deficiency of PTEN leads to aberrant chromosome segregation through downregulation of MAD2.
Sun Z, Lu J, Wu M, Li M, Bai L, Shi Z, Hao L, Wu Y
Molecular medicine reports 2019 Nov;20(5):4235-4243
Molecular medicine reports 2019 Nov;20(5):4235-4243
Downregulation of transgelin 2 promotes breast cancer metastasis by activating the reactive oxygen species/nuclear factor‑κB signaling pathway.
Yang L, Hong Q, Xu SG, Kuang XY, Di GH, Liu GY, Wu J, Shao ZM, Yu SJ
Molecular medicine reports 2019 Nov;20(5):4045-4258
Molecular medicine reports 2019 Nov;20(5):4045-4258
Identification of two novel RHO mutations in Chinese retinitis pigmentosa patients.
Wang J, Xu D, Zhu T, Zhou Y, Chen X, Wang F, Zhang J, Tian H, Gao F, Zhang J, Jin C, Xu J, Lu L, Liu Q, Xu GT
Experimental eye research 2019 Nov;188:107726
Experimental eye research 2019 Nov;188:107726
SNX3 suppresses the migration and invasion of colorectal cancer cells by reversing epithelial-to-mesenchymal transition via the β-catenin pathway.
Pan B, Zhang T, Yang W, Liu Y, Chen Y, Zhou Z, Tang Y, Zeng J, Liu Y, Zhao C, Guo Y
Oncology letters 2019 Nov;18(5):5332-5340
Oncology letters 2019 Nov;18(5):5332-5340
Exogenous hydrogen sulfide protects against high glucose-induced apoptosis and oxidative stress by inhibiting the STAT3/HIF-1α pathway in H9c2 cardiomyocytes.
Li J, Yuan YQ, Zhang L, Zhang H, Zhang SW, Zhang Y, Xuan XX, Wang MJ, Zhang JY
Experimental and therapeutic medicine 2019 Nov;18(5):3948-3958
Experimental and therapeutic medicine 2019 Nov;18(5):3948-3958
C2-lacking isoform of Nedd4-2 regulates excitatory synaptic strength through GluA1 ubiquitination-independent mechanisms.
Zhu J, Lee KY, Jong TT, Tsai NP
Journal of neurochemistry 2019 Nov;151(3):289-300
Journal of neurochemistry 2019 Nov;151(3):289-300
Atsttrin reduces lipopolysaccharide-induced neuroinflammation by inhibiting the nuclear factor kappa B signaling pathway.
Liu L, Qu Y, Liu Y, Zhao H, Ma HC, Noor AF, Ji CJ, Nie L, Si M, Cheng L
Neural regeneration research 2019 Nov;14(11):1994-2002
Neural regeneration research 2019 Nov;14(11):1994-2002
C9orf72 intermediate repeats are associated with corticobasal degeneration, increased C9orf72 expression and disruption of autophagy.
Cali CP, Patino M, Tai YK, Ho WY, McLean CA, Morris CM, Seeley WW, Miller BL, Gaig C, Vonsattel JPG, White CL 3rd, Roeber S, Kretzschmar H, Troncoso JC, Troakes C, Gearing M, Ghetti B, Van Deerlin VM, Lee VM, Trojanowski JQ, Mok KY, Ling H, Dickson DW, Schellenberg GD, Ling SC, Lee EB
Acta neuropathologica 2019 Nov;138(5):795-811
Acta neuropathologica 2019 Nov;138(5):795-811
Delta-aminolevulinic acid synthase 2 expression in combination with iron as modifiers of disease severity in erythropoietic protoporphyria.
Barman-Aksözen J, Halloy F, Iyer PS, Schümperli D, Minder AE, Hall J, Minder EI, Schneider-Yin X
Molecular genetics and metabolism 2019 Nov;128(3):304-308
Molecular genetics and metabolism 2019 Nov;128(3):304-308
Transmural pressure drives proliferation of human arterial smooth muscle cells via mechanism associated with NADPH oxidase and Survivin.
Ran K, Yang Z, Zhao Y, Wang X
Microvascular research 2019 Nov;126:103905
Microvascular research 2019 Nov;126:103905
IL-22 suppresses HSV-2 replication in human cervical epithelial cells.
Xu XQ, Liu Y, Zhang B, Liu H, Shao DD, Liu JB, Wang X, Zhou LN, Hu WH, Ho WZ
Cytokine 2019 Nov;123:154776
Cytokine 2019 Nov;123:154776
miR-9-5p attenuates ischemic stroke through targeting ERMP1-mediated endoplasmic reticulum stress.
Chi L, Jiao D, Nan G, Yuan H, Shen J, Gao Y
Acta histochemica 2019 Nov;121(8):151438
Acta histochemica 2019 Nov;121(8):151438
Serum proteomics analysis based on label-free revealed the protective effect of Chinese herbal formula Gu-Ben-Fang-Xiao.
Xing QQ, Liu LW, Zhao X, Lu Y, Dong YM, Liang ZQ
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Nov;119:109390
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Nov;119:109390
G9a and histone deacetylases are crucial for Snail2-mediated E-cadherin repression and metastasis in hepatocellular carcinoma.
Hu Y, Zheng Y, Dai M, Wang X, Wu J, Yu B, Zhang H, Cui Y, Kong W, Wu H, Yu X
Cancer science 2019 Nov;110(11):3442-3452
Cancer science 2019 Nov;110(11):3442-3452
The metabolic regulator small heterodimer partner contributes to the glucose and lipid homeostasis abnormalities induced by hepatitis C virus infection.
Chen J, Zhou Y, Zhuang Y, Qin T, Guo M, Jiang J, Niu J, Li JZ, Chen X, Wang Q
Metabolism: clinical and experimental 2019 Nov;100:153954
Metabolism: clinical and experimental 2019 Nov;100:153954
LINC00467 promotes cell proliferation and stemness in lung adenocarcinoma by sponging miR-4779 and miR-7978.
Chang Y, Yang L
Journal of cellular biochemistry 2019 Nov 3;
Journal of cellular biochemistry 2019 Nov 3;
Double-stranded RNA deaminase ADAR1 promotes the Zika virus replication by inhibiting the activation of protein kinase PKR.
Zhou S, Yang C, Zhao F, Huang Y, Lin Y, Huang C, Ma X, Du J, Wang Y, Long G, He J, Liu C, Zhang P
The Journal of biological chemistry 2019 Nov 29;294(48):18168-18180
The Journal of biological chemistry 2019 Nov 29;294(48):18168-18180
Microtubule destabilization caused by silicate via HDAC6 activation contributes to autophagic dysfunction in bone mesenchymal stem cells.
Li Z, Liu S, Fu T, Peng Y, Zhang J
Stem cell research & therapy 2019 Nov 27;10(1):351
Stem cell research & therapy 2019 Nov 27;10(1):351
Astaxanthin protects against osteoarthritis via Nrf2: a guardian of cartilage homeostasis.
Sun K, Luo J, Jing X, Guo J, Yao X, Hao X, Ye Y, Liang S, Lin J, Wang G, Guo F
Aging 2019 Nov 26;11(22):10513-10531
Aging 2019 Nov 26;11(22):10513-10531
Long noncoding RNA LINC01111 suppresses pancreatic cancer aggressiveness by regulating DUSP1 expression via microRNA-3924.
Pan S, Shen M, Zhou M, Shi X, He R, Yin T, Wang M, Guo X, Qin R
Cell death & disease 2019 Nov 25;10(12):883
Cell death & disease 2019 Nov 25;10(12):883
ZFP161 regulates replication fork stability and maintenance of genomic stability by recruiting the ATR/ATRIP complex.
Kim W, Zhao F, Wu R, Qin S, Nowsheen S, Huang J, Zhou Q, Chen Y, Deng M, Guo G, Luo K, Lou Z, Yuan J
Nature communications 2019 Nov 22;10(1):5304
Nature communications 2019 Nov 22;10(1):5304
CD105 Is Expressed in Ovarian Cancer Precursor Lesions and Is Required for Metastasis to the Ovary.
Bai S, Zhu W, Coffman L, Vlad A, Schwartz LE, Elishaev E, Drapkin R, Buckanovich RJ
Cancers 2019 Nov 2;11(11)
Cancers 2019 Nov 2;11(11)
Tissue plasminogen activator disrupts the blood-brain barrier through increasing the inflammatory response mediated by pericytes after cerebral ischemia.
Yang E, Cai Y, Yao X, Liu J, Wang Q, Jin W, Wu Q, Fan W, Qiu L, Kang C, Wu J
Aging 2019 Nov 18;11(22):10167-10182
Aging 2019 Nov 18;11(22):10167-10182
Efficient Delivery of Therapeutic siRNA by Fe3O4 Magnetic Nanoparticles into Oral Cancer Cells.
Jin L, Wang Q, Chen J, Wang Z, Xin H, Zhang D
Pharmaceutics 2019 Nov 17;11(11)
Pharmaceutics 2019 Nov 17;11(11)
Chemerin-induced macrophages pyroptosis in fetal brain tissue leads to cognitive disorder in offspring of diabetic dams.
Liang Z, Han L, Sun D, Chen Y, Wu Q, Zhang L, Zhou M, Chen D
Journal of neuroinflammation 2019 Nov 16;16(1):226
Journal of neuroinflammation 2019 Nov 16;16(1):226
Viral Nonstructural Protein 1 Induces Mitochondrion-Mediated Apoptosis in Mink Enteritis Virus Infection.
Lin P, Cheng Y, Song S, Qiu J, Yi L, Cao Z, Li J, Cheng S, Wang J
Journal of virology 2019 Nov 15;93(22)
Journal of virology 2019 Nov 15;93(22)
Nitidine chloride induces S phase cell cycle arrest and mitochondria-dependent apoptosis in HaCaT cells and ameliorates skin lesions in psoriasis-like mouse models.
Yang XG, Jiang BW, Jing QQ, Li WJ, Tan LP, Bao YL, Song ZB, Yu CL, Liu L, Liu YC, Li YX
European journal of pharmacology 2019 Nov 15;863:172680
European journal of pharmacology 2019 Nov 15;863:172680
Aberrant activation of RPB1 is critical for cell overgrowth in acute myeloid leukemia.
Yu Q, Xu Y, Zhuang H, Wu Z, Zhang L, Li J, Yang L, Wu B, Wang P, Zhang X, Gan X, Liang Y, Zheng S, Yu X, Gu Y, Xu R
Experimental cell research 2019 Nov 15;384(2):111653
Experimental cell research 2019 Nov 15;384(2):111653
A thiazole-derived oridonin analogue exhibits antitumor activity by directly and allosterically inhibiting STAT3.
Shen X, Zhao L, Chen P, Gong Y, Liu D, Zhang X, Dai L, Sun Q, Lou J, Jin Z, Zhang B, Niu D, Chen C, Qi X, Jia D
The Journal of biological chemistry 2019 Nov 15;294(46):17471-17486
The Journal of biological chemistry 2019 Nov 15;294(46):17471-17486
β-Caryophyllene protects against ischemic stroke by promoting polarization of microglia toward M2 phenotype via the TLR4 pathway.
Tian X, Liu H, Xiang F, Xu L, Dong Z
Life sciences 2019 Nov 15;237:116915
Life sciences 2019 Nov 15;237:116915
A dual functional ruthenium arene complex induces differentiation and apoptosis of acute promyelocytic leukemia cells.
Huang H, Cao K, Kong Y, Yuan S, Liu H, Wang Y, Liu Y
Chemical science 2019 Nov 14;10(42):9721-9728
Chemical science 2019 Nov 14;10(42):9721-9728
The miR-28-5p-CAMTA2 axis regulates colon cancer progression via Wnt/β-catenin signaling.
Luan XF, Wang L, Gai XF
Journal of cellular biochemistry 2019 Nov 10;
Journal of cellular biochemistry 2019 Nov 10;
SPOP inhibits mice pancreatic stellate cell activation by promoting FADD degradation in cerulein-induced chronic pancreatitis.
Tan P, Wang A, Chen H, Du Y, Qian B, Shi H, Zhang Y, Xia X, Fu W
Experimental cell research 2019 Nov 1;384(1):111606
Experimental cell research 2019 Nov 1;384(1):111606
Prematurity blunts the feeding-induced stimulation of translation initiation signaling and protein synthesis in muscle of neonatal piglets.
Naberhuis JK, Suryawan A, Nguyen HV, Hernandez-Garcia A, Cruz SM, Lau PE, Olutoye OO, Stoll B, Burrin DG, Fiorotto ML, Davis TA
American journal of physiology. Endocrinology and metabolism 2019 Nov 1;317(5):E839-E851
American journal of physiology. Endocrinology and metabolism 2019 Nov 1;317(5):E839-E851
Aurone derivatives as Vps34 inhibitors that modulate autophagy.
Li G, Boyle JW, Ko CN, Zeng W, Wong VKW, Wan JB, Chan PWH, Ma DL, Leung CH
Acta pharmaceutica Sinica. B 2019 May;9(3):537-544
Acta pharmaceutica Sinica. B 2019 May;9(3):537-544
Regulation of insulin resistance by targeting the insulin-like growth factor 1 receptor with microRNA-122-5p in hepatic cells.
Dong L, Hou X, Liu F, Tao H, Zhang Y, Zhao H, Song G
Cell biology international 2019 May;43(5):553-564
Cell biology international 2019 May;43(5):553-564
RPS7 promotes cell migration through targeting epithelial-mesenchymal transition in prostate cancer.
Wen Y, An Z, Qiao B, Zhang C, Zhang Z
Urologic oncology 2019 May;37(5):297.e1-297.e7
Urologic oncology 2019 May;37(5):297.e1-297.e7
Identification of genes with universally upregulated or downregulated expressions in colorectal cancer.
Song K, Su W, Liu Y, Zhang J, Liang Q, Li N, Guan Q, He J, Bai X, Zhao W, Guo Z
Journal of gastroenterology and hepatology 2019 May;34(5):880-889
Journal of gastroenterology and hepatology 2019 May;34(5):880-889
Taurine alleviates repression of betaine-homocysteine S-methyltransferase and significantly improves the efficacy of long-term betaine treatment in a mouse model of cystathionine β-synthase-deficient homocystinuria.
Maclean KN, Jiang H, Phinney WN, Keating AK, Hurt KJ, Stabler SP
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 May;33(5):6339-6353
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 May;33(5):6339-6353
Adipose-Specific Lipin-1 Overexpression Renders Hepatic Ferroptosis and Exacerbates Alcoholic Steatohepatitis in Mice.
Zhou Z, Ye TJ, Bonavita G, Daniels M, Kainrad N, Jogasuria A, You M
Hepatology communications 2019 May;3(5):656-669
Hepatology communications 2019 May;3(5):656-669
Serine/arginine protein-specific kinase 2 promotes the development and progression of pancreatic cancer by downregulating Numb and p53.
Wang G, Sheng W, Shi X, Li X, Zhou J, Dong M
The FEBS journal 2019 May;286(9):1668-1682
The FEBS journal 2019 May;286(9):1668-1682
MicroRNA-92a promotes vascular smooth muscle cell proliferation and migration through the ROCK/MLCK signalling pathway.
Wang J, Zhang C, Li C, Zhao D, Li S, Ma L, Cui Y, Wei X, Zhao Y, Gao Y
Journal of cellular and molecular medicine 2019 May;23(5):3696-3710
Journal of cellular and molecular medicine 2019 May;23(5):3696-3710
Ectopic expression of miR-944 impairs colorectal cancer cell proliferation and invasion by targeting GATA binding protein 6.
Tang JT, Zhao J, Sheng W, Zhou JP, Dong Q, Dong M
Journal of cellular and molecular medicine 2019 May;23(5):3483-3494
Journal of cellular and molecular medicine 2019 May;23(5):3483-3494
The pattern-recognition molecule mindin binds integrin Mac-1 to promote macrophage phagocytosis via Syk activation and NF-κB p65 translocation.
Liu YS, Wang LF, Cheng XS, Huo YN, Ouyang XM, Liang LY, Lin Y, Wu JF, Ren JL, Guleng B
Journal of cellular and molecular medicine 2019 May;23(5):3402-3416
Journal of cellular and molecular medicine 2019 May;23(5):3402-3416
The RNA N6-methyladenosine modification landscape of human fetal tissues.
Xiao S, Cao S, Huang Q, Xia L, Deng M, Yang M, Jia G, Liu X, Shi J, Wang W, Li Y, Liu S, Zhu H, Tan K, Luo Q, Zhong M, He C, Xia L
Nature cell biology 2019 May;21(5):651-661
Nature cell biology 2019 May;21(5):651-661
ERα and Wnt/β‑catenin signaling pathways are involved in angelicin‑dependent promotion of osteogenesis.
Ge L, Cui Y, Liu B, Yin X, Pang J, Han J
Molecular medicine reports 2019 May;19(5):3469-3476
Molecular medicine reports 2019 May;19(5):3469-3476
β-Catenin and Yes-Associated Protein 1 Cooperate in Hepatoblastoma Pathogenesis.
Min Q, Molina L, Li J, Adebayo Michael AO, Russell JO, Preziosi ME, Singh S, Poddar M, Matz-Soja M, Ranganathan S, Bell AW, Gebhardt R, Gaunitz F, Yu J, Tao J, Monga SP
The American journal of pathology 2019 May;189(5):1091-1104
The American journal of pathology 2019 May;189(5):1091-1104
A novel function of anaphase promoting complex subunit 10 in tumor progression in non-small cell lung cancer.
Wang Y, Han T, Gan M, Guo M, Xie C, Jin J, Zhang S, Wang P, Cao J, Wang JB
Cell cycle (Georgetown, Tex.) 2019 May;18(9):1019-1032
Cell cycle (Georgetown, Tex.) 2019 May;18(9):1019-1032
Demethylation of the HACE1 gene promoter inhibits the proliferation of human liver cancer cells.
Yu Z, Li Y, Han T, Liu Z
Oncology letters 2019 May;17(5):4361-4368
Oncology letters 2019 May;17(5):4361-4368
Upregulated forkhead-box A3 elevates the expression of forkhead-box A1 and forkhead-box A2 to promote metastasis in esophageal cancer.
Chen B, Yu J, Lu L, Dong F, Zhou F, Tao X, Sun E
Oncology letters 2019 May;17(5):4351-4360
Oncology letters 2019 May;17(5):4351-4360
Nano hydroxyapatite induces glioma cell apoptosis by suppressing NF-κB signaling pathway.
Guo G, Tian A, Lan X, Fu C, Yan Z, Wang C
Experimental and therapeutic medicine 2019 May;17(5):4080-4088
Experimental and therapeutic medicine 2019 May;17(5):4080-4088
Attenuation of interferon regulatory factor 7 activity in local infectious sites of trachea and lung for preventing the development of acute lung injury caused by influenza A virus.
Yang L, Tu L, Zhao P, Wang Y, Wang S, Lu W, Wang Y, Li X, Yu Y, Hua S, Wang L
Immunology 2019 May;157(1):37-51
Immunology 2019 May;157(1):37-51
SMCR8 negatively regulates AKT and MTORC1 signaling to modulate lysosome biogenesis and tissue homeostasis.
Lan Y, Sullivan PM, Hu F
Autophagy 2019 May;15(5):871-885
Autophagy 2019 May;15(5):871-885
The ALS-FTD-linked gene product, C9orf72, regulates neuronal morphogenesis via autophagy.
Ho WY, Tai YK, Chang JC, Liang J, Tyan SH, Chen S, Guan JL, Zhou H, Shen HM, Koo E, Ling SC
Autophagy 2019 May;15(5):827-842
Autophagy 2019 May;15(5):827-842
FAM175B promotes apoptosis by inhibiting ATF4 ubiquitination in esophageal squamous cell carcinoma.
Zhao Y, Yu Y, Li H, Zhang Z, Guo S, Zhu S, Guo Q, Li P, Min L, Zhang S
Molecular oncology 2019 May;13(5):1150-1165
Molecular oncology 2019 May;13(5):1150-1165
Nrf2 controls iron homeostasis in haemochromatosis and thalassaemia via Bmp6 and hepcidin.
Lim PJ, Duarte TL, Arezes J, Garcia-Santos D, Hamdi A, Pasricha SR, Armitage AE, Mehta H, Wideman S, Santos AG, Santos-Gonçalves A, Morovat A, Hughes JR, Soilleux E, Wang CY, Bayer AL, Klenerman P, Willberg CB, Hartley RC, Murphy MP, Babitt JL, Ponka P, Porto G, Drakesmith H
Nature metabolism 2019 May;1(5):519-531
Nature metabolism 2019 May;1(5):519-531
Sox17 is required for endothelial regeneration following inflammation-induced vascular injury.
Liu M, Zhang L, Marsboom G, Jambusaria A, Xiong S, Toth PT, Benevolenskaya EV, Rehman J, Malik AB
Nature communications 2019 May 9;10(1):2126
Nature communications 2019 May 9;10(1):2126
Inhibiting Glutamine-Dependent mTORC1 Activation Ameliorates Liver Cancers Driven by β-Catenin Mutations.
Adebayo Michael AO, Ko S, Tao J, Moghe A, Yang H, Xu M, Russell JO, Pradhan-Sundd T, Liu S, Singh S, Poddar M, Monga JS, Liu P, Oertel M, Ranganathan S, Singhi A, Rebouissou S, Zucman-Rossi J, Ribback S, Calvisi D, Qvartskhava N, Görg B, Häussinger D, Chen X, Monga SP
Cell metabolism 2019 May 7;29(5):1135-1150.e6
Cell metabolism 2019 May 7;29(5):1135-1150.e6
Thyrotropin aggravates atherosclerosis by promoting macrophage inflammation in plaques.
Yang C, Lu M, Chen W, He Z, Hou X, Feng M, Zhang H, Bo T, Zhou X, Yu Y, Zhang H, Zhao M, Wang L, Yu C, Gao L, Jiang W, Zhang Q, Zhao J
The Journal of experimental medicine 2019 May 6;216(5):1182-1198
The Journal of experimental medicine 2019 May 6;216(5):1182-1198
Adipose HuR protects against diet-induced obesity and insulin resistance.
Li J, Gong L, Liu S, Zhang Y, Zhang C, Tian M, Lu H, Bu P, Yang J, Ouyang C, Jiang X, Wu J, Zhang Y, Min Q, Zhang C, Zhang W
Nature communications 2019 May 30;10(1):2375
Nature communications 2019 May 30;10(1):2375
USP36 protects proximal tubule cells from ischemic injury by stabilizing c-Myc and SOD2.
Liu Q, Sheng W, Ma Y, Zhen J, Roy S, Alvira Jafar C, Xin W, Wan Q
Biochemical and biophysical research communications 2019 May 28;513(2):502-508
Biochemical and biophysical research communications 2019 May 28;513(2):502-508
p53 suppression is essential for oncogenic SPAG5 upregulation in lung adenocarcinoma.
Wang T, Li K, Song H, Xu D, Liao Y, Jing B, Guo W, Hu M, Kuang Y, Sun B, Ling J, Zhang T, Xu J, Yao F, Deng J
Biochemical and biophysical research communications 2019 May 28;513(2):319-325
Biochemical and biophysical research communications 2019 May 28;513(2):319-325
HMGB1 contributes to SASH1 methylation to attenuate astrocyte adhesion.
Wu R, Yan Y, Ma C, Chen H, Dong Z, Wang Y, Liu Y, Liu M, Yang L
Cell death & disease 2019 May 28;10(6):417
Cell death & disease 2019 May 28;10(6):417
Inhibition of the IGF-1-PI3K-Akt-mTORC2 pathway in lipid rafts increases neuronal vulnerability in a genetic lysosomal glycosphingolipidosis.
Sural-Fehr T, Singh H, Cantuti-Catelvetri L, Zhu H, Marshall MS, Rebiai R, Jastrzebski MJ, Givogri MI, Rasenick MM, Bongarzone ER
Disease models & mechanisms 2019 May 23;12(5)
Disease models & mechanisms 2019 May 23;12(5)
PLA Electrospun Scaffolds for Three-Dimensional Triple-Negative Breast Cancer Cell Culture.
Polonio-Alcalá E, Rabionet M, Gallardo X, Angelats D, Ciurana J, Ruiz-Martínez S, Puig T
Polymers 2019 May 23;11(5)
Polymers 2019 May 23;11(5)
Shen Shuai IIRecipe attenuates renal injury and fibrosis in chronic kidney disease by regulating NLRP3 inflammasome and Sirt1/Smad3 deacetylation pathway.
Wang M, Yang L, Yang J, Wang C
BMC complementary and alternative medicine 2019 May 22;19(1):107
BMC complementary and alternative medicine 2019 May 22;19(1):107
Isodunnianol alleviates doxorubicin-induced myocardial injury by activating protective autophagy.
Chen C, Jiang L, Zhang M, Pan X, Peng C, Huang W, Jiang Q
Food & function 2019 May 22;10(5):2651-2657
Food & function 2019 May 22;10(5):2651-2657
Estrogen negatively regulates the renal epithelial sodium channel (ENaC) by promoting Derlin-1 expression and AMPK activation.
Zhang X, Ge Y, Bukhari AA, Zhu Q, Shen Y, Li M, Sun H, Su D, Liang X
Experimental & molecular medicine 2019 May 21;51(5):1-12
Experimental & molecular medicine 2019 May 21;51(5):1-12
Tumor Cell "Slimming" Regulates Tumor Progression through PLCL1/UCP1-Mediated Lipid Browning.
Xiong Z, Xiao W, Bao L, Xiong W, Xiao H, Qu Y, Yuan C, Ruan H, Cao Q, Wang K, Song Z, Wang C, Hu W, Ru Z, Tong J, Cheng G, Xu T, Meng X, Shi J, Chen Z, Yang H, Chen K, Zhang X
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2019 May 17;6(10):1801862
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2019 May 17;6(10):1801862
M2 macrophages promote NSCLC metastasis by upregulating CRYAB.
Guo Z, Song J, Hao J, Zhao H, Du X, Li E, Kuang Y, Yang F, Wang W, Deng J, Wang Q
Cell death & disease 2019 May 16;10(6):377
Cell death & disease 2019 May 16;10(6):377
Triptolide prevents proliferation and migration of Esophageal Squamous Cell Cancer via MAPK/ERK signaling pathway.
Yanchun M, Yi W, Lu W, Yu Q, Jian Y, Pengzhou K, Ting Y, Hongyi L, Fang W, Xiaolong C, Yongping C
European journal of pharmacology 2019 May 15;851:43-51
European journal of pharmacology 2019 May 15;851:43-51
Oral Administration of a Select Mixture of Lactobacillus and Bacillus Alleviates Inflammation and Maintains Mucosal Barrier Integrity in the Ileum of Pigs Challenged with Salmonella Infantis.
Liu X, Xia B, He T, Li D, Su JH, Guo L, Wang JF, Zhu YH
Microorganisms 2019 May 15;7(5)
Microorganisms 2019 May 15;7(5)
Hic-5 regulates Src-induced invadopodia rosette formation and organization.
Gulvady AC, Forsythe IJ, Turner CE
Molecular biology of the cell 2019 May 15;30(11):1298-1313
Molecular biology of the cell 2019 May 15;30(11):1298-1313
FGFR2 Promotes Expression of PD-L1 in Colorectal Cancer via the JAK/STAT3 Signaling Pathway.
Li P, Huang T, Zou Q, Liu D, Wang Y, Tan X, Wei Y, Qiu H
Journal of immunology (Baltimore, Md. : 1950) 2019 May 15;202(10):3065-3075
Journal of immunology (Baltimore, Md. : 1950) 2019 May 15;202(10):3065-3075
Sodium ferulate protects against influenza virus infection by activation of the TLR7/9-MyD88-IRF7 signaling pathway and inhibition of the NF-κB signaling pathway.
Zhu Y, Shao Y, Qu X, Guo J, Yang J, Zhou Z, Wang S
Biochemical and biophysical research communications 2019 May 14;512(4):793-798
Biochemical and biophysical research communications 2019 May 14;512(4):793-798
The Glycoprotein and Nucleocapsid Protein of Hantaviruses Manipulate Autophagy Flux to Restrain Host Innate Immune Responses.
Wang K, Ma H, Liu H, Ye W, Li Z, Cheng L, Zhang L, Lei Y, Shen L, Zhang F
Cell reports 2019 May 14;27(7):2075-2091.e5
Cell reports 2019 May 14;27(7):2075-2091.e5
Cynomorium songaricum Rupr demonstrates phytoestrogenic or phytoandrogenic like activities that attenuates benign prostatic hyperplasia via regulating steroid 5-α-reductase.
Tao R, Miao L, Yu X, Orgah JO, Barnabas O, Chang Y, Liu E, Fan G, Gao X
Journal of ethnopharmacology 2019 May 10;235:65-74
Journal of ethnopharmacology 2019 May 10;235:65-74
Anterior Gradient-2 monoclonal antibody inhibits lung cancer growth and metastasis by upregulating p53 pathway and without exerting any toxicological effects: A preclinical study.
Negi H, Merugu SB, Mangukiya HB, Li Z, Zhou B, Sehar Q, Kamle S, Yunus FU, Mashausi DS, Wu Z, Li D
Cancer letters 2019 May 1;449:125-134
Cancer letters 2019 May 1;449:125-134
USP39 regulates DNA damage response and chemo-radiation resistance by deubiquitinating and stabilizing CHK2.
Wu J, Chen Y, Geng G, Li L, Yin P, Nowsheen S, Li Y, Wu C, Liu J, Zhao F, Kim W, Zhou Q, Huang J, Guo G, Zhang C, Tu X, Gao X, Lou Z, Luo K, Qiao H, Yuan J
Cancer letters 2019 May 1;449:114-124
Cancer letters 2019 May 1;449:114-124
Astragaloside IV Regulates the PI3K/Akt/HO-1 Signaling Pathway and Inhibits H9c2 Cardiomyocyte Injury Induced by Hypoxia-Reoxygenation.
Yang P, Zhou Y, Xia Q, Yao L, Chang X
Biological & pharmaceutical bulletin 2019 May 1;42(5):721-727
Biological & pharmaceutical bulletin 2019 May 1;42(5):721-727
Inactivation of Cyclic AMP Response Element Transcription Caused by Constitutive p38 Activation Is Mediated by Hyperphosphorylation-Dependent CRTC2 Nucleocytoplasmic Transport.
Ma H, Liu Z, Zhong CQ, Liu Y, Zhang Z, Liang Y, Li J, Han S, Han J
Molecular and cellular biology 2019 May 1;39(9)
Molecular and cellular biology 2019 May 1;39(9)
Fatty acid-binding protein 3 contributes to ischemic heart injury by regulating cardiac myocyte apoptosis and MAPK pathways.
Zhuang L, Li C, Chen Q, Jin Q, Wu L, Lu L, Yan X, Chen K
American journal of physiology. Heart and circulatory physiology 2019 May 1;316(5):H971-H984
American journal of physiology. Heart and circulatory physiology 2019 May 1;316(5):H971-H984
Inhibition of mitochondrial complex I activity attenuates neointimal hyperplasia by inhibiting smooth muscle cell proliferation and migration.
Yin J, Xia W, Wu M, Zhang Y, Huang S, Zhang A, Jia Z
Chemico-biological interactions 2019 May 1;304:73-82
Chemico-biological interactions 2019 May 1;304:73-82
Reactivation of nonsense-mediated mRNA decay protects against C9orf72 dipeptide-repeat neurotoxicity.
Xu W, Bao P, Jiang X, Wang H, Qin M, Wang R, Wang T, Yang Y, Lorenzini I, Liao L, Sattler R, Xu J
Brain : a journal of neurology 2019 May 1;142(5):1349-1364
Brain : a journal of neurology 2019 May 1;142(5):1349-1364
Sirt3 mediates the protective effect of hydrogen in inhibiting ROS-induced retinal senescence.
Li R, Liu Y, Xie J, Huang X, Zhang L, Liu H, Li L
Free radical biology & medicine 2019 May 1;135:116-124
Free radical biology & medicine 2019 May 1;135:116-124
Oxytocin facilitates the proliferation, migration and osteogenic differentiation of human periodontal stem cells in vitro.
Ge B, Liu H, Liang Q, Shang L, Wang T, Ge S
Archives of oral biology 2019 Mar;99:126-133
Archives of oral biology 2019 Mar;99:126-133
Nr5a2 promotes cancer stem cell properties and tumorigenesis in nonsmall cell lung cancer by regulating Nanog.
Ye T, Li J, Sun Z, Liu Y, Kong L, Zhou S, Tang J, Wang J, Xing HR
Cancer medicine 2019 Mar;8(3):1232-1245
Cancer medicine 2019 Mar;8(3):1232-1245
MicroRNA-186 is associated with hypoxia-inducible factor-1α expression in chronic obstructive pulmonary disease.
Lin L, Sun J, Wu D, Lin D, Sun D, Li Q, Chen J, Niu H, He P, Ding Y
Molecular genetics & genomic medicine 2019 Mar;7(3):e531
Molecular genetics & genomic medicine 2019 Mar;7(3):e531
Gallic Acid Suppresses Cardiac Hypertrophic Remodeling and Heart Failure.
Yan X, Zhang YL, Zhang L, Zou LX, Chen C, Liu Y, Xia YL, Li HH
Molecular nutrition & food research 2019 Mar;63(5):e1800807
Molecular nutrition & food research 2019 Mar;63(5):e1800807
Herbal decoctosome is a novel form of medicine.
Li X, Liang Z, Du J, Wang Z, Mei S, Li Z, Zhao Y, Zhao D, Ma Y, Ye J, Xu J, Zhao Y, Chang J, Qin Y, Yu L, Wang C, Jiang C
Science China. Life sciences 2019 Mar;62(3):333-348
Science China. Life sciences 2019 Mar;62(3):333-348
Pb disrupts autophagic flux through inhibiting the formation and activity of lysosomes in neural cells.
Gu X, Han M, Du Y, Wu Y, Xu Y, Zhou X, Ye D, Wang HL
Toxicology in vitro : an international journal published in association with BIBRA 2019 Mar;55:43-50
Toxicology in vitro : an international journal published in association with BIBRA 2019 Mar;55:43-50
Role of heparan sulfate in the Zika virus entry, replication, and cell death.
Gao H, Lin Y, He J, Zhou S, Liang M, Huang C, Li X, Liu C, Zhang P
Virology 2019 Mar;529:91-100
Virology 2019 Mar;529:91-100
NS38 is required for aquareovirus replication via interaction with viral core proteins and host eIF3A.
Zhang J, Guo H, Zhang F, Chen Q, Chang M, Fang Q
Virology 2019 Mar;529:216-225
Virology 2019 Mar;529:216-225
Continuous translation of circularized mRNA improves recombinant protein titer.
Costello A, Lao NT, Barron N, Clynes M
Metabolic engineering 2019 Mar;52:284-292
Metabolic engineering 2019 Mar;52:284-292
Regulation of Neurotransmitter Release by Amyloid Precursor Protein Through Synapsin Phosphorylation.
Liu A, Zhang Y, Han L, He G, Xie W, Zhou Z, Jia Z
Neurochemical research 2019 Mar;44(3):683-691
Neurochemical research 2019 Mar;44(3):683-691
Bromodomain‑containing protein 7 sensitizes breast cancer cells to paclitaxel by activating Bcl2‑antagonist/killer protein.
Ma J, Niu W, Wang X, Zhou Y, Wang H, Liu F, Liu Y, Guo J, Xiong W, Zeng Z, Fan S, Li X, Nie X, Li G, Gui R, Luo Y, Zhou M
Oncology reports 2019 Mar;41(3):1487-1496
Oncology reports 2019 Mar;41(3):1487-1496
miR-4739 mediates pleural fibrosis by targeting bone morphogenetic protein 7.
Wang M, Xiong L, Jiang LJ, Lu YZ, Liu F, Song LJ, Xiang F, He XL, Yu F, Shuai SY, Ma WL, Ye H
EBioMedicine 2019 Mar;41:670-682
EBioMedicine 2019 Mar;41:670-682
3D human bone marrow stromal and endothelial cell spheres promote bone healing in an osteogenic niche.
Inglis S, Kanczler JM, Oreffo ROC
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 Mar;33(3):3279-3290
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 Mar;33(3):3279-3290
Oncostatin M-induced upregulation of SDF-1 improves Bone marrow stromal cell migration in a rat middle cerebral artery occlusion stroke model.
Han J, Feng Z, Xie Y, Li F, Lv B, Hua T, Zhang Z, Sun C, Su D, Ouyang Q, Cai Y, Zou Y, Tang Y, Sun H, Jiang X
Experimental neurology 2019 Mar;313:49-59
Experimental neurology 2019 Mar;313:49-59
PARylation regulates stress granule dynamics, phase separation, and neurotoxicity of disease-related RNA-binding proteins.
Duan Y, Du A, Gu J, Duan G, Wang C, Gui X, Ma Z, Qian B, Deng X, Zhang K, Sun L, Tian K, Zhang Y, Jiang H, Liu C, Fang Y
Cell research 2019 Mar;29(3):233-247
Cell research 2019 Mar;29(3):233-247
β‑elemene inhibits oxygen‑induced retinal neovascularization via promoting miR‑27a and reducing VEGF expression.
Zhang W, Chen L, Geng J, Liu L, Xu L
Molecular medicine reports 2019 Mar;19(3):2307-2316
Molecular medicine reports 2019 Mar;19(3):2307-2316
Modulation of α-adrenoceptor signalling protects photoreceptors after retinal detachment by inhibiting oxidative stress and inflammation.
Li T, Yang S, She X, Yan Q, Zhang P, Zhu H, Wang F, Luo X, Sun X
British journal of pharmacology 2019 Mar;176(6):801-813
British journal of pharmacology 2019 Mar;176(6):801-813
NF-κB and Poly (ADP-ribose) Polymerase 1 Form a Positive Feedback Loop that Regulates DNA Repair in Acute Myeloid Leukemia Cells.
Li D, Luo Y, Chen X, Zhang L, Wang T, Zhuang Y, Fan Y, Xu J, Chen Y, Wu L
Molecular cancer research : MCR 2019 Mar;17(3):761-772
Molecular cancer research : MCR 2019 Mar;17(3):761-772
miRNA profiling in the hippocampus of attention-deficit/hyperactivity disorder rats.
Tian T, Zhang Y, Wu T, Yang L, Chen C, Li N, Li Y, Xu S, Fu Z, Cui X, Ji C, Chi X, Tong M, Chen R, Hong Q, Hu Y
Journal of cellular biochemistry 2019 Mar;120(3):3621-3629
Journal of cellular biochemistry 2019 Mar;120(3):3621-3629
MET mutation causes muscular dysplasia and arthrogryposis.
Zhou H, Lian C, Wang T, Yang X, Xu C, Su D, Zheng S, Huang X, Liao Z, Zhou T, Qiu X, Chen Y, Gao B, Li Y, Wang X, You G, Fu Q, Gurnett C, Huang D, Su P
EMBO molecular medicine 2019 Mar;11(3)
EMBO molecular medicine 2019 Mar;11(3)
MLKL deficiency inhibits DSS-induced colitis independent of intestinal microbiota.
Zhang J, Qin D, Yang YJ, Hu GQ, Qin XX, Du CT, Chen W
Molecular immunology 2019 Mar;107:132-141
Molecular immunology 2019 Mar;107:132-141
Combinatory FK506 and Minocycline Treatment Alleviates Prion-Induced Neurodegenerative Events via Caspase-Mediated MAPK-NRF2 Pathway.
Shah SZA, Zhao D, Taglialatela G, Hussain T, Dong H, Sabir N, Mangi MH, Wu W, Lai M, Zhang X, Duan Y, Wang L, Zhou X, Yang L
International journal of molecular sciences 2019 Mar 6;20(5)
International journal of molecular sciences 2019 Mar 6;20(5)
Circadian control of stress granules by oscillating EIF2α.
Wang R, Jiang X, Bao P, Qin M, Xu J
Cell death & disease 2019 Mar 4;10(3):215
Cell death & disease 2019 Mar 4;10(3):215
Neuroprotective Effect of Dioscin on the Aging Brain.
Qi Y, Li R, Xu L, Yin L, Xu Y, Han X, Peng J
Molecules (Basel, Switzerland) 2019 Mar 30;24(7)
Molecules (Basel, Switzerland) 2019 Mar 30;24(7)
Silencing of XRCC4 increases radiosensitivity of triple-negative breast cancer cells.
Wen Y, Dai G, Wang L, Fu K, Zuo S
Bioscience reports 2019 Mar 29;39(3)
Bioscience reports 2019 Mar 29;39(3)
Cysteine Dioxygenase Regulates the Epithelial Morphogenesis of Mammary Gland via Cysteine Sulfinic Acid.
Zhao J, Han Y, Ma X, Zhou Y, Yuan S, Shen Q, Ye G, Liu H, Fu P, Zhang G, Qiao B, Liu A
iScience 2019 Mar 29;13:173-189
iScience 2019 Mar 29;13:173-189
Viral-Mediated AURKB Cleavage Promotes Cell Segregation and Tumorigenesis.
Zhu Q, Ding L, Zi Z, Gao S, Wang C, Wang Y, Zhu C, Yuan Z, Wei F, Cai Q
Cell reports 2019 Mar 26;26(13):3657-3671.e5
Cell reports 2019 Mar 26;26(13):3657-3671.e5
MicroRNA-29a Disrupts DNMT3b to Ameliorate Diet-Induced Non-Alcoholic Steatohepatitis in Mice.
Yang YL, Kuo HC, Wang FS, Huang YH
International journal of molecular sciences 2019 Mar 26;20(6)
International journal of molecular sciences 2019 Mar 26;20(6)
H2S restores the cardioprotective effects of ischemic post-conditioning by upregulating HB-EGF/EGFR signaling.
Zhang Y, Gao J, Sun W, Wen X, Xi Y, Wang Y, Wei C, Xu C, Li H
Aging 2019 Mar 26;11(6):1745-1758
Aging 2019 Mar 26;11(6):1745-1758
Ribosomal Proteins Regulate MHC Class I Peptide Generation for Immunosurveillance.
Wei J, Kishton RJ, Angel M, Conn CS, Dalla-Venezia N, Marcel V, Vincent A, Catez F, Ferré S, Ayadi L, Marchand V, Dersh D, Gibbs JS, Ivanov IP, Fridlyand N, Couté Y, Diaz JJ, Qian SB, Staudt LM, Restifo NP, Yewdell JW
Molecular cell 2019 Mar 21;73(6):1162-1173.e5
Molecular cell 2019 Mar 21;73(6):1162-1173.e5
Genetically Encoded FapR-NLuc as a Biosensor to Determine Malonyl-CoA in Situ at Subcellular Scales.
Du Y, Hu H, Pei X, Du K, Wei T
Bioconjugate chemistry 2019 Mar 20;30(3):826-832
Bioconjugate chemistry 2019 Mar 20;30(3):826-832
A GPR17-cAMP-Lactate Signaling Axis in Oligodendrocytes Regulates Whole-Body Metabolism.
Ou Z, Ma Y, Sun Y, Zheng G, Wang S, Xing R, Chen X, Han Y, Wang J, Lu QR, Zhao TJ, Chen Y
Cell reports 2019 Mar 12;26(11):2984-2997.e4
Cell reports 2019 Mar 12;26(11):2984-2997.e4
p53-targeted lincRNA-p21 acts as a tumor suppressor by inhibiting JAK2/STAT3 signaling pathways in head and neck squamous cell carcinoma.
Jin S, Yang X, Li J, Yang W, Ma H, Zhang Z
Molecular cancer 2019 Mar 11;18(1):38
Molecular cancer 2019 Mar 11;18(1):38
Porcine Hemagglutinating Encephalomyelitis Virus Activation of the Integrin α5β1-FAK-Cofilin Pathway Causes Cytoskeletal Rearrangement To Promote Its Invasion of N2a Cells.
Lv X, Li Z, Guan J, Hu S, Zhang J, Lan Y, Zhao K, Lu H, Song D, He H, Gao F, He W
Journal of virology 2019 Mar 1;93(5)
Journal of virology 2019 Mar 1;93(5)
PRL-3 Promotes Ubiquitination and Degradation of AURKA and Colorectal Cancer Progression via Dephosphorylation of FZR1.
Zhang C, Qu L, Lian S, Meng L, Min L, Liu J, Song Q, Shen L, Shou C
Cancer research 2019 Mar 1;79(5):928-940
Cancer research 2019 Mar 1;79(5):928-940
HOXD-AS1 promotes the epithelial to mesenchymal transition of ovarian cancer cells by regulating miR-186-5p and PIK3R3.
Dong S, Wang R, Wang H, Ding Q, Zhou X, Wang J, Zhang K, Long Y, Lu S, Hong T, Ren H, Wong K, Sheng X, Wang Y, Zeng Y
Journal of experimental & clinical cancer research : CR 2019 Mar 1;38(1):110
Journal of experimental & clinical cancer research : CR 2019 Mar 1;38(1):110
Candidate-based screening via gene modulation in human neurons and astrocytes implicates FERMT2 in Aβ and TAU proteostasis.
Sullivan SE, Liao M, Smith RV, White C, Lagomarsino VN, Xu J, Taga M, Bennett DA, De Jager PL, Young-Pearse TL
Human molecular genetics 2019 Mar 1;28(5):718-735
Human molecular genetics 2019 Mar 1;28(5):718-735
In Vitro and In Vivo Anti-Inflammatory Effects of Polyphyllin VII through Downregulating MAPK and NF-κB Pathways.
Zhang C, Li C, Jia X, Wang K, Tu Y, Wang R, Liu K, Lu T, He C
Molecules (Basel, Switzerland) 2019 Mar 1;24(5)
Molecules (Basel, Switzerland) 2019 Mar 1;24(5)
Molecular characterization of caspase-8-like and its expression induced by microcystin-LR in grass carp (Ctenopharygodon idella).
Wei L, He L, Fu J, Liu Y, Ruan J, Liu L, Zhong Q
Fish & shellfish immunology 2019 Jun;89:727-735
Fish & shellfish immunology 2019 Jun;89:727-735
Defective Central Immune Tolerance Induced by High-Dose D-Galactose Resembles Aging.
Du HM, Wang YJ, Liu X, Wang SL, Wu SM, Yuan Z, Zhu XK
Biochemistry. Biokhimiia 2019 Jun;84(6):617-626
Biochemistry. Biokhimiia 2019 Jun;84(6):617-626
Exosomal cyclophilin A as a novel noninvasive biomarker for Epstein-Barr virus associated nasopharyngeal carcinoma.
Liu L, Zuo L, Yang J, Xin S, Zhang J, Zhou J, Li G, Tang J, Lu J
Cancer medicine 2019 Jun;8(6):3142-3151
Cancer medicine 2019 Jun;8(6):3142-3151
Activation of cGMP/PKG/p65 signaling associated with PDE5-Is downregulates CCL5 secretion by CD8 + T cells in benign prostatic hyperplasia.
Jin S, Xiang P, Liu J, Yang Y, Hu S, Sheng J, He Q, Yu W, Han W, Jin J, Peng J
The Prostate 2019 Jun;79(8):909-919
The Prostate 2019 Jun;79(8):909-919
Minimally modified low-density lipoprotein upregulates the ETB and α1 receptors in mouse mesenteric arteries in vivo by activating the PI3K/Akt pathway.
Zeng ZS, Lin J, Xu CB, Cao L, Chen C, Li J
The Journal of pharmacy and pharmacology 2019 Jun;71(6):937-944
The Journal of pharmacy and pharmacology 2019 Jun;71(6):937-944
Deficiency of ZnT8 Promotes Adiposity and Metabolic Dysfunction by Increasing Peripheral Serotonin Production.
Mao Z, Lin H, Su W, Li J, Zhou M, Li Z, Zhou B, Yang Q, Zhou M, Pan K, He J, Zhang W
Diabetes 2019 Jun;68(6):1197-1209
Diabetes 2019 Jun;68(6):1197-1209
Activated CRH receptors inhibit autophagy by repressing conversion of LC3BI to LC3BII.
Jin L, Qian Y, Zhou J, Dai L, Cao C, Zhu C, Li S
Cellular signalling 2019 Jun;58:119-130
Cellular signalling 2019 Jun;58:119-130
A comprehensive study on donor-matched comparisons of three types of mesenchymal stem cells-containing cells from human dental tissue.
Xing Y, Zhang Y, Wu X, Zhao B, Ji Y, Xu X
Journal of periodontal research 2019 Jun;54(3):286-299
Journal of periodontal research 2019 Jun;54(3):286-299
Effects of 3-dimensional Bioprinting Alginate/Gelatin Hydrogel Scaffold Extract on Proliferation and Differentiation of Human Dental Pulp Stem Cells.
Yu H, Zhang X, Song W, Pan T, Wang H, Ning T, Wei Q, Xu HHK, Wu B, Ma D
Journal of endodontics 2019 Jun;45(6):706-715
Journal of endodontics 2019 Jun;45(6):706-715
The circRNA circPTPRA suppresses epithelial-mesenchymal transitioning and metastasis of NSCLC cells by sponging miR-96-5p.
Wei S, Zheng Y, Jiang Y, Li X, Geng J, Shen Y, Li Q, Wang X, Zhao C, Chen Y, Qian Z, Zhou J, Li W
EBioMedicine 2019 Jun;44:182-193
EBioMedicine 2019 Jun;44:182-193
FasL on decidual macrophages mediates trophoblast apoptosis: A potential cause of recurrent miscarriage.
Ding J, Yin T, Yan N, Cheng Y, Yang J
International journal of molecular medicine 2019 Jun;43(6):2376-2386
International journal of molecular medicine 2019 Jun;43(6):2376-2386
Obesity-associated family with sequence similarity 13, member A (FAM13A) is dispensable for adipose development and insulin sensitivity.
Tang J, Zhou H, Sahay K, Xu W, Yang J, Zhang W, Chen W
International journal of obesity (2005) 2019 Jun;43(6):1269-1280
International journal of obesity (2005) 2019 Jun;43(6):1269-1280
Probenecid Relieves Cerebral Dysfunction of Sepsis by Inhibiting Pannexin 1-Dependent ATP Release.
Zhang Z, Lei Y, Yan C, Mei X, Jiang T, Ma Z, Wang Q
Inflammation 2019 Jun;42(3):1082-1092
Inflammation 2019 Jun;42(3):1082-1092
Early Pattern of Epstein-Barr Virus Infection in Gastric Epithelial Cells by "Cell-in-cell".
Yue W, Zhu M, Zuo L, Xin S, Zhang J, Liu L, Li S, Dang W, Zhang S, Xie Y, Zhu F, Lu J
Virologica Sinica 2019 Jun;34(3):253-261
Virologica Sinica 2019 Jun;34(3):253-261
Reduced asymmetric dimethylarginine accumulation through inhibition of the type I protein arginine methyltransferases promotes renal fibrosis in obstructed kidneys.
Wu M, Lin P, Li L, Chen D, Yang X, Xu L, Zhou B, Wang C, Zhang Y, Luo C, Ye C
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 Jun;33(6):6948-6956
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 Jun;33(6):6948-6956
Suppression of puerarin on polymethylmethacrylate-induced lesion of peri-implant by inhibiting NF-κB activation in vitro and in vivo.
Yan B, Zhou H, Chu J, Cao X
Pathology, research and practice 2019 Jun;215(6):152372
Pathology, research and practice 2019 Jun;215(6):152372
An SOD1 deficiency aggravates proteasome inhibitor bortezomib-induced testicular damage in mice.
Homma T, Fujii J
Biochimica et biophysica acta. General subjects 2019 Jun;1863(6):1108-1115
Biochimica et biophysica acta. General subjects 2019 Jun;1863(6):1108-1115
The p53/miRNAs/Ccna2 pathway serves as a novel regulator of cellular senescence: Complement of the canonical p53/p21 pathway.
Xu S, Wu W, Huang H, Huang R, Xie L, Su A, Liu S, Zheng R, Yuan Y, Zheng HL, Sun X, Xiong XD, Liu X
Aging cell 2019 Jun;18(3):e12918
Aging cell 2019 Jun;18(3):e12918
Enhanced responsiveness of platelets to vicagrel in IL-10-deficient mice through STAT3-dependent up-regulation of the hydrolase arylacetamide deacetylase in the intestine.
Jia YM, Zhou H, Tai T, Gu TT, Ji JZ, Mi QY, Huang BB, Li YF, Zhu T, Xie HG
British journal of pharmacology 2019 Jun;176(11):1717-1727
British journal of pharmacology 2019 Jun;176(11):1717-1727
Inhibition of Wee1 sensitizes AML cells to ATR inhibitor VE-822-induced DNA damage and apoptosis.
Qi W, Xu X, Wang M, Li X, Wang C, Sun L, Zhao D, Sun L
Biochemical pharmacology 2019 Jun;164:273-282
Biochemical pharmacology 2019 Jun;164:273-282
AC002454.1 and CDK6 synergistically promote endometrial cell migration and invasion in endometriosis.
Liu J, Wang Y, Chen P, Ma Y, Wang S, Tian Y, Wang A, Wang D
Reproduction (Cambridge, England) 2019 Jun;157(6):535-543
Reproduction (Cambridge, England) 2019 Jun;157(6):535-543
Hydrogen sulfide protects against DSS-induced colitis by inhibiting NLRP3 inflammasome.
Qin M, Long F, Wu W, Yang D, Huang M, Xiao C, Chen X, Liu X, Zhu YZ
Free radical biology & medicine 2019 Jun;137:99-109
Free radical biology & medicine 2019 Jun;137:99-109
Amplification of USP13 drives non-small cell lung cancer progression mediated by AKT/MAPK signaling.
Wu Y, Zhang Y, Liu C, Zhang Y, Wang D, Wang S, Wu Y, Liu F, Li Q, Liu X, Zaky MY, Yan D, Liu S
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Jun;114:108831
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Jun;114:108831
Antithrombotic Effect of shRNA Target F12 Mediated by Adeno-Associated Virus.
Li F, Yang X, Liu J, Shu K, Shen C, Chen T, Yang W, Li S, Wang X, Jiang M
Molecular therapy. Nucleic acids 2019 Jun 7;16:295-301
Molecular therapy. Nucleic acids 2019 Jun 7;16:295-301
Insulin-like growth factor-1 attenuates oxidative stress-induced hepatocyte premature senescence in liver fibrogenesis via regulating nuclear p53-progerin interaction.
Luo X, Jiang X, Li J, Bai Y, Li Z, Wei P, Sun S, Liang Y, Han S, Li X, Zhang B
Cell death & disease 2019 Jun 6;10(6):451
Cell death & disease 2019 Jun 6;10(6):451
Death-associated protein kinase 3 deficiency alleviates vascular calcification via AMPK-mediated inhibition of endoplasmic reticulum stress.
Li KX, Du Q, Wang HP, Sun HJ
European journal of pharmacology 2019 Jun 5;852:90-98
European journal of pharmacology 2019 Jun 5;852:90-98
Alternative transcription start site selection in ACSS2 controls its nuclear localization and promotes ribosome biosynthesis in hepatocellular carcinoma.
Wang YH, Huang S, Zhu L, Yang Q, Yang XM, Gu JR, Zhang ZG, Nie HZ, Li J
Biochemical and biophysical research communications 2019 Jun 30;514(3):632-638
Biochemical and biophysical research communications 2019 Jun 30;514(3):632-638
NLRC5 inhibits neointima formation following vascular injury and directly interacts with PPARγ.
Luan P, Jian W, Xu X, Kou W, Yu Q, Hu H, Li D, Wang W, Feinberg MW, Zhuang J, Xu Y, Peng W
Nature communications 2019 Jun 28;10(1):2882
Nature communications 2019 Jun 28;10(1):2882
Pervasive Chromatin-RNA Binding Protein Interactions Enable RNA-Based Regulation of Transcription.
Xiao R, Chen JY, Liang Z, Luo D, Chen G, Lu ZJ, Chen Y, Zhou B, Li H, Du X, Yang Y, San M, Wei X, Liu W, Lécuyer E, Graveley BR, Yeo GW, Burge CB, Zhang MQ, Zhou Y, Fu XD
Cell 2019 Jun 27;178(1):107-121.e18
Cell 2019 Jun 27;178(1):107-121.e18
Transcriptional Regulation of gga-miR-451 by AhR:Arnt in Mycoplasma gallisepticum (HS Strain) Infection.
Zhao Y, Fu Y, Sun Y, Zou M, Peng X
International journal of molecular sciences 2019 Jun 24;20(12)
International journal of molecular sciences 2019 Jun 24;20(12)
miR-211 facilitates platinum chemosensitivity by blocking the DNA damage response (DDR) in ovarian cancer.
Wang T, Hao D, Yang S, Ma J, Yang W, Zhu Y, Weng M, An X, Wang X, Li Y, Wu D, Tang J, Yang C, He Y, Zhang L, Jin X, Wang G, Li Z, Zheng T, Meng H, Feng Y, Li X
Cell death & disease 2019 Jun 24;10(7):495
Cell death & disease 2019 Jun 24;10(7):495
Identification of metabolic vulnerabilities of receptor tyrosine kinases-driven cancer.
Jin N, Bi A, Lan X, Xu J, Wang X, Liu Y, Wang T, Tang S, Zeng H, Chen Z, Tan M, Ai J, Xie H, Zhang T, Liu D, Huang R, Song Y, Leung EL, Yao X, Ding J, Geng M, Lin SH, Huang M
Nature communications 2019 Jun 20;10(1):2701
Nature communications 2019 Jun 20;10(1):2701
Low Polymerase Activity Attributed to PA Drives the Acquisition of the PB2 E627K Mutation of H7N9 Avian Influenza Virus in Mammals.
Liang L, Jiang L, Li J, Zhao Q, Wang J, He X, Huang S, Wang Q, Zhao Y, Wang G, Sun N, Deng G, Shi J, Tian G, Zeng X, Jiang Y, Liu L, Liu J, Chen P, Bu Z, Kawaoka Y, Chen H, Li C
mBio 2019 Jun 18;10(3)
mBio 2019 Jun 18;10(3)
Induction of Fibrosis and Autophagy in Kidney Cells by Vinyl Chloride.
Hsu YH, Chuang HC, Lee YH, Lin YF, Chiu YJ, Wang YL, Wu MS, Chiu HW
Cells 2019 Jun 17;8(6)
Cells 2019 Jun 17;8(6)
Cellular Interleukin Enhancer-Binding Factor 2, ILF2, Inhibits Japanese Encephalitis Virus Replication In Vitro.
Cui X, Qian P, Rao T, Wei Y, Zhao F, Zhang H, Chen H, Li X
Viruses 2019 Jun 17;11(6)
Viruses 2019 Jun 17;11(6)
Insulin transcriptionally down-regulates carboxylesterases through pregnane X receptor in an Akt-dependent manner.
Yang X, Zhang X, Liu Y, Xi T, Xiong J
Toxicology 2019 Jun 15;422:60-68
Toxicology 2019 Jun 15;422:60-68
NOL12 Repression Induces Nucleolar Stress-Driven Cellular Senescence and Is Associated with Normative Aging.
Pinho M, Macedo JC, Logarinho E, Pereira PS
Molecular and cellular biology 2019 Jun 15;39(12)
Molecular and cellular biology 2019 Jun 15;39(12)
Dihydromyricetin alleviates acetaminophen-induced liver injury via the regulation of transformation, lipid homeostasis, cell death and regeneration.
Dong S, Ji J, Hu L, Wang H
Life sciences 2019 Jun 15;227:20-29
Life sciences 2019 Jun 15;227:20-29
Fine particulate matter-induced cardiovascular injury is associated with NLRP3 inflammasome activation in Apo E-/- mice.
Du X, Jiang S, Zeng X, Zhang J, Pan K, Song L, Zhou J, Kan H, Sun Q, Zhao J, Xie Y
Ecotoxicology and environmental safety 2019 Jun 15;174:92-99
Ecotoxicology and environmental safety 2019 Jun 15;174:92-99
Heartland virus antagonizes type I and III interferon antiviral signaling by inhibiting phosphorylation and nuclear translocation of STAT2 and STAT1.
Feng K, Deng F, Hu Z, Wang H, Ning YJ
The Journal of biological chemistry 2019 Jun 14;294(24):9503-9517
The Journal of biological chemistry 2019 Jun 14;294(24):9503-9517
Small molecule inhibitor of TGF-β signaling enables robust osteogenesis of autologous GMSCs to successfully repair minipig severe maxillofacial bone defects.
Shi A, Heinayati A, Bao D, Liu H, Ding X, Tong X, Wang L, Wang B, Qin H
Stem cell research & therapy 2019 Jun 13;10(1):172
Stem cell research & therapy 2019 Jun 13;10(1):172
CDK9 modulates circadian clock by attenuating REV-ERBα activity.
Ou J, Li H, Qiu P, Li Q, Chang HC, Tang YC
Biochemical and biophysical research communications 2019 Jun 11;513(4):967-973
Biochemical and biophysical research communications 2019 Jun 11;513(4):967-973
Arsenic trioxide inhibits EMT in hepatocellular carcinoma by promoting lncRNA MEG3 via PKM2.
Fan Z, He J, Fu T, Zhang W, Yang G, Qu X, Liu R, Lv L, Wang J
Biochemical and biophysical research communications 2019 Jun 11;513(4):834-840
Biochemical and biophysical research communications 2019 Jun 11;513(4):834-840
Targeting ATGL to rescue BSCL2 lipodystrophy and its associated cardiomyopathy.
Zhou H, Lei X, Yan Y, Lydic T, Li J, Weintraub NL, Su H, Chen W
JCI insight 2019 Jun 11;5
JCI insight 2019 Jun 11;5
microRNA-378a Regulates the Reactive Oxygen Species (ROS)/Phosphatidylinositol 3-Kinases (PI3K)/AKT Signaling Pathway in Human Lens Epithelial Cells and Cataract.
Liu Y, Li H, Liu Y
Medical science monitor : international medical journal of experimental and clinical research 2019 Jun 10;25:4314-4321
Medical science monitor : international medical journal of experimental and clinical research 2019 Jun 10;25:4314-4321
Role of TMPRSS4 Modulation in Breast Cancer Cell Proliferation.
Assani G, Yessoufou A, Xiong Y, Segbo J, Yu X, Zhou F, Zhou Y
Asian Pacific journal of cancer prevention : APJCP 2019 Jun 1;20(6):1849-1856
Asian Pacific journal of cancer prevention : APJCP 2019 Jun 1;20(6):1849-1856
Nrf2 deficiency aggravates Angiotensin II-induced cardiac injury by increasing hypertrophy and enhancing IL-6/STAT3-dependent inflammation.
Chen D, Li Z, Bao P, Chen M, Zhang M, Yan F, Xu Y, Ji C, Hu X, Sanchis D, Zhang Y, Ye J
Biochimica et biophysica acta. Molecular basis of disease 2019 Jun 1;1865(6):1253-1264
Biochimica et biophysica acta. Molecular basis of disease 2019 Jun 1;1865(6):1253-1264
Aerobic exercise regulates synaptic transmission and reactive oxygen species production in the paraventricular nucleus of spontaneously hypertensive rats.
Li C, Li Y, Zhao Z, Lv Y, Gu B, Zhao L
Brain research 2019 Jun 1;1712:82-92
Brain research 2019 Jun 1;1712:82-92
Esrrb plays important roles in maintaining self-renewal of trophoblast stem cells (TSCs) and reprogramming somatic cells to induced TSCs.
Gao H, Gao R, Zhang L, Xiu W, Zang R, Wang H, Zhang Y, Chen J, Gao Y, Gao S
Journal of molecular cell biology 2019 Jun 1;11(6):463-473
Journal of molecular cell biology 2019 Jun 1;11(6):463-473
Cardamonin from a medicinal herb protects against LPS-induced septic shock by suppressing NLRP3 inflammasome.
Wang Z, Xu G, Gao Y, Zhan X, Qin N, Fu S, Li R, Niu M, Wang J, Liu Y, Xiao X, Bai Z
Acta pharmaceutica Sinica. B 2019 Jul;9(4):734-744
Acta pharmaceutica Sinica. B 2019 Jul;9(4):734-744
IL-25 promotes cisplatin resistance of lung cancer cells by activating NF-κB signaling pathway to increase of major vault protein.
Shen W, Qiu Y, Li J, Wu C, Liu Z, Zhang X, Hu X, Liao Y, Wang H
Cancer medicine 2019 Jul;8(7):3491-3501
Cancer medicine 2019 Jul;8(7):3491-3501
Anti-inflammatory and antitumour activity of various extracts and compounds from the fruits of Piper longum L.
Guo Z, Xu J, Xia J, Wu Z, Lei J, Yu J
The Journal of pharmacy and pharmacology 2019 Jul;71(7):1162-1171
The Journal of pharmacy and pharmacology 2019 Jul;71(7):1162-1171
MicroRNA-135b alleviates MPP+-mediated Parkinson's disease in in vitro model through suppressing FoxO1-induced NLRP3 inflammasome and pyroptosis.
Zeng R, Luo DX, Li HP, Zhang QS, Lei SS, Chen JH
Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 2019 Jul;65:125-133
Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 2019 Jul;65:125-133
APS could potentially activate hepatic insulin signaling in HFD-induced IR mice.
Sun J, Liu Y, Yu J, Wu J, Gao W, Ran L, Jiang R, Guo M, Han D, Liu B, Wang N, Li Y, Huang H, Zeng L, Gao Y, Li X, Wu Y
Journal of molecular endocrinology 2019 Jul;63(1):77-91
Journal of molecular endocrinology 2019 Jul;63(1):77-91
MicroRNA-221 sensitizes chronic myeloid leukemia cells to imatinib by targeting STAT5.
Jiang X, Cheng Y, Hu C, Zhang A, Ren Y, Xu X
Leukemia & lymphoma 2019 Jul;60(7):1709-1720
Leukemia & lymphoma 2019 Jul;60(7):1709-1720
Comparison of intracellular responses between HBV genotype A and C infection in human hepatocyte chimeric mice.
Tsushima K, Tsuge M, Hiraga N, Uchida T, Murakami E, Makokha GN, Kurihara M, Nomura M, Hiyama Y, Fujino H, Ono A, Nakahara T, Yamauchi M, Abe-Chayama H, Kawaoka T, Miki D, Imamura M, Aikata H, Hayes CN, Chayama K
Journal of gastroenterology 2019 Jul;54(7):650-659
Journal of gastroenterology 2019 Jul;54(7):650-659
Clearance of apoptotic cells by mesenchymal stem cells contributes to immunosuppression via PGE2.
Zhang Z, Huang S, Wu S, Qi J, Li W, Liu S, Cong Y, Chen H, Lu L, Shi S, Wang D, Chen W, Sun L
EBioMedicine 2019 Jul;45:341-350
EBioMedicine 2019 Jul;45:341-350
The potential role of pregnancy-associated plasma protein-A2 in angiogenesis and development of preeclampsia.
Chen X, Chen K, Feng Y, Ren C, Li W, Xiao J, Fan L, Beejadhursing R, Xi L, Chen S
Hypertension research : official journal of the Japanese Society of Hypertension 2019 Jul;42(7):970-980
Hypertension research : official journal of the Japanese Society of Hypertension 2019 Jul;42(7):970-980
Luteolin suppresses colorectal cancer cell metastasis via regulation of the miR‑384/pleiotrophin axis.
Yao Y, Rao C, Zheng G, Wang S
Oncology reports 2019 Jul;42(1):131-141
Oncology reports 2019 Jul;42(1):131-141
Dynasore Suppresses mTORC1 Activity and Induces Autophagy to Regulate the Clearance of Protein Aggregates in Neurodegenerative Diseases.
Chen Y, Xu S, Wang N, Ma Q, Peng P, Yu Y, Zhang L, Ying Z, Wang H
Neurotoxicity research 2019 Jul;36(1):108-116
Neurotoxicity research 2019 Jul;36(1):108-116
Reduction of PGRN increased fibrosis during skin wound healing in mice.
Li SS, Zhang MX, Wang Y, Wang W, Zhao CM, Sun XM, Dong GK, Li ZR, Yin WJ, Zhu B, Cai HX
Histology and histopathology 2019 Jul;34(7):765-774
Histology and histopathology 2019 Jul;34(7):765-774
Activation of prostaglandin EP4 receptor attenuates the induction of cyclooxygenase-2 expression by EP2 receptor activation in human amnion fibroblasts: implications for parturition.
Lu JW, Wang WS, Zhou Q, Gan XW, Myatt L, Sun K
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 Jul;33(7):8148-8160
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 Jul;33(7):8148-8160
Resveratrol targets TyrRS acetylation to protect against radiation-induced damage.
Gao P, Li N, Ji K, Wang Y, Xu C, Liu Y, Wang Q, Wang J, He N, Sun Z, Du L, Liu Q
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 Jul;33(7):8083-8093
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 Jul;33(7):8083-8093
Notch signaling activation induces cell death in MAPKi-resistant melanoma cells.
Mikheil DM, Prabhakar K, Arshad A, Rodriguez CI, Newton MA, Setaluri V
Pigment cell & melanoma research 2019 Jul;32(4):528-539
Pigment cell & melanoma research 2019 Jul;32(4):528-539
Molecular basis of vasohibins-mediated detyrosination and its impact on spindle function and mitosis.
Liao S, Rajendraprasad G, Wang N, Eibes S, Gao J, Yu H, Wu G, Tu X, Huang H, Barisic M, Xu C
Cell research 2019 Jul;29(7):533-547
Cell research 2019 Jul;29(7):533-547
Alcohol dehydrogenase of Candida albicans triggers differentiation of THP-1 cells into macrophages.
Liu Y, Ou Y, Sun L, Li W, Yang J, Zhang X, Hu Y
Journal of advanced research 2019 Jul;18:137-145
Journal of advanced research 2019 Jul;18:137-145
Neuroprotection of Fasting Mimicking Diet on MPTP-Induced Parkinson's Disease Mice via Gut Microbiota and Metabolites.
Zhou ZL, Jia XB, Sun MF, Zhu YL, Qiao CM, Zhang BP, Zhao LP, Yang Q, Cui C, Chen X, Shen YQ
Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics 2019 Jul;16(3):741-760
Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics 2019 Jul;16(3):741-760
Harnessing the anti-cancer natural product nimbolide for targeted protein degradation.
Spradlin JN, Hu X, Ward CC, Brittain SM, Jones MD, Ou L, To M, Proudfoot A, Ornelas E, Woldegiorgis M, Olzmann JA, Bussiere DE, Thomas JR, Tallarico JA, McKenna JM, Schirle M, Maimone TJ, Nomura DK
Nature chemical biology 2019 Jul;15(7):747-755
Nature chemical biology 2019 Jul;15(7):747-755
RTN1-C is involved in high glucose-aggravated neuronal cell subjected to oxygen-glucose deprivation and reoxygenation injury via endoplasmic reticulum stress.
Lin M, Ling J, Geng X, Zhang J, Du J, Chen L
Brain research bulletin 2019 Jul;149:129-136
Brain research bulletin 2019 Jul;149:129-136
Long-term pulmonary exposure to multi-walled carbon nanotubes promotes breast cancer metastatic cascades.
Lu X, Zhu Y, Bai R, Wu Z, Qian W, Yang L, Cai R, Yan H, Li T, Pandey V, Liu Y, Lobie PE, Chen C, Zhu T
Nature nanotechnology 2019 Jul;14(7):719-727
Nature nanotechnology 2019 Jul;14(7):719-727
Aqueous extract of Salvia miltiorrhiza Bunge-Radix Puerariae herb pair ameliorates diabetic vascular injury by inhibiting oxidative stress in streptozotocin-induced diabetic rats.
Zhao W, Yuan Y, Zhao H, Han Y, Chen X
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2019 Jul;129:97-107
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2019 Jul;129:97-107
Effect of Hypoxia on the Muscle Fiber Switching Signal Pathways CnA/NFATc1 and Myostatin in Mouse Myocytes.
Lixin L, Juan W, Yun B, Jingwei L, Xiuju Y, Xiaomao L, Zhiwei Z, Xiaoyan H, Yanjun D, Hongquan L, Haidong W
Acta histochemica 2019 Jul;121(5):539-545
Acta histochemica 2019 Jul;121(5):539-545
Hsa_circ_0023404 enhances cervical cancer metastasis and chemoresistance through VEGFA and autophagy signaling by sponging miR-5047.
Guo J, Chen M, Ai G, Mao W, Li H, Zhou J
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Jul;115:108957
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Jul;115:108957
Taurine protects against arsenic trioxide-induced insulin resistance via ROS-Autophagy pathway in skeletal muscle.
Yang L, Qiu T, Yao X, Jiang L, Wei S, Pei P, Wang Z, Bai J, Liu X, Yang G, Liu S, Sun X
The international journal of biochemistry & cell biology 2019 Jul;112:50-60
The international journal of biochemistry & cell biology 2019 Jul;112:50-60
Long noncoding RNA actin filament-associated protein 1 antisense RNA 1 promotes malignant phenotype through binding with lysine-specific demethylase 1 and repressing HMG box-containing protein 1 in non-small-cell lung cancer.
Yu S, Yang D, Ye Y, Liu P, Chen Z, Lei T, Pu J, Liu L, Wang Z
Cancer science 2019 Jul;110(7):2211-2225
Cancer science 2019 Jul;110(7):2211-2225
Lysine glutarylation in human sperm is associated with progressive motility.
Cheng YM, Hu XN, Peng Z, Pan TT, Wang F, Chen HY, Chen WQ, Zhang Y, Zeng XH, Luo T
Human reproduction (Oxford, England) 2019 Jul 8;34(7):1186-1194
Human reproduction (Oxford, England) 2019 Jul 8;34(7):1186-1194
microRNA-16-5p promotes 3T3-L1 adipocyte differentiation through regulating EPT1.
Xu J, Zhang L, Shu G, Wang B
Biochemical and biophysical research communications 2019 Jul 5;514(4):1251-1256
Biochemical and biophysical research communications 2019 Jul 5;514(4):1251-1256
Comparative interactome analysis reveals distinct and overlapping properties of Raf family kinases.
Zhang XY, Guo H, Huang Y, Hao PQ, Yang Y, Liu Y, Guo XX, Hao Q, An S, Xu TR
Biochemical and biophysical research communications 2019 Jul 5;514(4):1217-1223
Biochemical and biophysical research communications 2019 Jul 5;514(4):1217-1223
Long noncoding RNA PCAT1, a novel serum-based biomarker, enhances cell growth by sponging miR-326 in oesophageal squamous cell carcinoma.
Huang L, Wang Y, Chen J, Wang Y, Zhao Y, Wang Y, Ma Y, Chen X, Liu W, Li Z, Zhao L, Shan B, Dong X, Li D, Shao S, Song Y, Zhan Q, Liu X
Cell death & disease 2019 Jul 4;10(7):513
Cell death & disease 2019 Jul 4;10(7):513
TSPAN12 Precedes Tumor Proliferation by Cell Cycle Control in Ovarian Cancer.
Ji G, Liang H, Wang F, Wang N, Fu S, Cui X
Molecules and cells 2019 Jul 31;42(7):557-567
Molecules and cells 2019 Jul 31;42(7):557-567
LncRNA-H19 promotes hepatic lipogenesis by directly regulating miR-130a/PPARγ axis in non-alcoholic fatty liver disease.
Liu J, Tang T, Wang GD, Liu B
Bioscience reports 2019 Jul 31;39(7)
Bioscience reports 2019 Jul 31;39(7)
A novel RP2 missense mutation Q158P identified in an X-linked retinitis pigmentosa family impaired RP2 protein stability.
Zhang J, Gao F, Du C, Wang J, Pi X, Guo W, Li J, Li H, Ma Y, Zhang W, Mu H, Hu Y, Cui X
Gene 2019 Jul 30;707:86-92
Gene 2019 Jul 30;707:86-92
Melatonin attenuates cadmium-induced ovulatory dysfunction by suppressing endoplasmic reticulum stress and cell apoptosis.
Yang Q, Zhu J, Luo X, Li F, Cong L, Wang Y, Sun Y
Reproductive biology and endocrinology : RB&E 2019 Jul 29;17(1):61
Reproductive biology and endocrinology : RB&E 2019 Jul 29;17(1):61
MiR-205 mediated APC regulation contributes to pancreatic cancer cell proliferation.
Qin RF, Zhang J, Huo HR, Yuan ZJ, Xue JD
World journal of gastroenterology 2019 Jul 28;25(28):3775-3786
World journal of gastroenterology 2019 Jul 28;25(28):3775-3786
Osteoprotegerin (OPG) Promotes Recruitment of Endothelial Progenitor Cells (EPCs) via CXCR4 Signaling Pathway to Improve Bone Defect Repair.
Zhang R, Liu J, Yu S, Sun D, Wang X, Fu J, Shen J, Xie Z
Medical science monitor : international medical journal of experimental and clinical research 2019 Jul 27;25:5572-5579
Medical science monitor : international medical journal of experimental and clinical research 2019 Jul 27;25:5572-5579
Simultaneous knockdown of YAP and TAZ increases apoptosis of hepatocellular carcinoma cells under hypoxic condition.
Yan B, Li T, Shen L, Zhou Z, Liu X, Wang X, Sun X
Biochemical and biophysical research communications 2019 Jul 23;515(2):275-281
Biochemical and biophysical research communications 2019 Jul 23;515(2):275-281
Diallyl Disulfide Induces Apoptosis and Autophagy in Human Osteosarcoma MG-63 Cells through the PI3K/Akt/mTOR Pathway.
Yue Z, Guan X, Chao R, Huang C, Li D, Yang P, Liu S, Hasegawa T, Guo J, Li M
Molecules (Basel, Switzerland) 2019 Jul 23;24(14)
Molecules (Basel, Switzerland) 2019 Jul 23;24(14)
Blood autophagy defect causes accelerated non-hematopoietic organ aging.
Fang Y, Zhu L, An N, Jiang G, Qian J, Zhao R, Yuan N, Zhang S, Wang J
Aging 2019 Jul 21;11(14):4910-4922
Aging 2019 Jul 21;11(14):4910-4922
Inhibitory Effects of Oxymatrine on Transdifferentiation of Neonatal Rat Cardiac Fibroblasts to Myofibroblasts Induced by Aldosterone via Keap1/Nrf2 Signaling Pathways In Vitro.
Yang Y, Chen S, Tao L, Gan S, Luo H, Xu Y, Shen X
Medical science monitor : international medical journal of experimental and clinical research 2019 Jul 20;25:5375-5388
Medical science monitor : international medical journal of experimental and clinical research 2019 Jul 20;25:5375-5388
SFRS11 Loss Leads to Aging-Associated Cognitive Decline by Modulating LRP8 and ApoE.
Raihan O, Brishti A, Li Q, Zhang Q, Li D, Li X, Zhang Q, Xie Z, Li J, Zhang J, Liu Q
Cell reports 2019 Jul 2;28(1):78-90.e6
Cell reports 2019 Jul 2;28(1):78-90.e6
Structural and functional analyses of hepatitis B virus X protein BH3-like domain and Bcl-xL interaction.
Zhang TY, Chen HY, Cao JL, Xiong HL, Mo XB, Li TL, Kang XZ, Zhao JH, Yin B, Zhao X, Huang CH, Yuan Q, Xue D, Xia NS, Yuan YA
Nature communications 2019 Jul 19;10(1):3192
Nature communications 2019 Jul 19;10(1):3192
CD4 Expression and Env Conformation Are Critical for HIV-1 Restriction by SERINC5.
Zhang X, Shi J, Qiu X, Chai Q, Frabutt DA, Schwartz RC, Zheng YH
Journal of virology 2019 Jul 15;93(14)
Journal of virology 2019 Jul 15;93(14)
A novel, highly-water-soluble apigenin derivative provides neuroprotection following ischemia in male rats by regulating the ERK/Nrf2/HO-1 pathway.
Zhang S, Xu S, Duan H, Zhu Z, Yang Z, Cao J, Zhao Y, Huang Z, Wu Q, Duan J
European journal of pharmacology 2019 Jul 15;855:208-215
European journal of pharmacology 2019 Jul 15;855:208-215
LncRNA FOXD2-AS1 plays an oncogenic role in hepatocellular carcinoma through epigenetically silencing CDKN1B(p27) via EZH2.
Xu K, Zhang Z, Qian J, Wang S, Yin S, Xie H, Zhou L, Zheng S
Experimental cell research 2019 Jul 15;380(2):198-204
Experimental cell research 2019 Jul 15;380(2):198-204
Matrine inhibits IL-1β secretion in primary porcine alveolar macrophages through the MyD88/NF-κB pathway and NLRP3 inflammasome.
Sun P, Sun N, Yin W, Sun Y, Fan K, Guo J, Khan A, He Y, Li H
Veterinary research 2019 Jul 12;50(1):53
Veterinary research 2019 Jul 12;50(1):53
KHDRBS3 regulates the permeability of blood-tumor barrier via cDENND4C/miR-577 axis.
Wu P, Gao Y, Shen S, Xue Y, Liu X, Ruan X, Shao L, Liu Y, Wang P
Cell death & disease 2019 Jul 11;10(7):536
Cell death & disease 2019 Jul 11;10(7):536
Insulin-like growth factor 2 mRNA binding protein 2 promotes aerobic glycolysis and cell proliferation in pancreatic ductal adenocarcinoma via stabilizing GLUT1 mRNA.
Huang S, Wu Z, Cheng Y, Wei W, Hao L
Acta biochimica et biophysica Sinica 2019 Jul 10;51(7):743-752
Acta biochimica et biophysica Sinica 2019 Jul 10;51(7):743-752
Knockdown ATG4C inhibits gliomas progression and promotes temozolomide chemosensitivity by suppressing autophagic flux.
Wen ZP, Zeng WJ, Chen YH, Li H, Wang JY, Cheng Q, Yu J, Zhou HH, Liu ZZ, Xiao J, Chen XP
Journal of experimental & clinical cancer research : CR 2019 Jul 10;38(1):298
Journal of experimental & clinical cancer research : CR 2019 Jul 10;38(1):298
Metformin facilitates the proliferation, migration, and osteogenic differentiation of periodontal ligament stem cells in vitro.
Zhang R, Liang Q, Kang W, Ge S
Cell biology international 2019 Jul 10;
Cell biology international 2019 Jul 10;
Activation of 20-HETE/PPARs involved in reno-therapeutic effect of naringenin on diabetic nephropathy.
Ding S, Qiu H, Huang J, Chen R, Zhang J, Huang B, Zou X, Cheng O, Jiang Q
Chemico-biological interactions 2019 Jul 1;307:116-124
Chemico-biological interactions 2019 Jul 1;307:116-124
Toxicological exploration of peptide-based cationic liposomes in siRNA delivery.
Zhu Y, Meng Y, Zhao Y, Zhu J, Xu H, Zhang E, Shi L, Du L, Liu G, Zhang C, Xu X, Kang X, Zhen Y, Zhang S
Colloids and surfaces. B, Biointerfaces 2019 Jul 1;179:66-76
Colloids and surfaces. B, Biointerfaces 2019 Jul 1;179:66-76
Exosomal miR-1229 derived from colorectal cancer cells promotes angiogenesis by targeting HIPK2.
Hu HY, Yu CH, Zhang HH, Zhang SZ, Yu WY, Yang Y, Chen Q
International journal of biological macromolecules 2019 Jul 1;132:470-477
International journal of biological macromolecules 2019 Jul 1;132:470-477
Phenylephrine Alleviates 131I Radiation Damage in Submandibular Gland Through Maintaining Mitochondrial Homeostasis.
Wang XY, Yu J, Zhang FY, Liu KJ, Xiang B
International journal of radiation oncology, biology, physics 2019 Jul 1;104(3):644-655
International journal of radiation oncology, biology, physics 2019 Jul 1;104(3):644-655
Extracellular matrix remodeling effects of serum amyloid A1 in the human amnion: Implications for fetal membrane rupture.
Wang YW, Wang WS, Wang LY, Bao YR, Lu JW, Lu Y, Zhang CY, Li WJ, Sun K, Ying H
American journal of reproductive immunology (New York, N.Y. : 1989) 2019 Jan;81(1):e13073
American journal of reproductive immunology (New York, N.Y. : 1989) 2019 Jan;81(1):e13073
Overexpression of P2X4 receptor in Schwann cells promotes motor and sensory functional recovery and remyelination via BDNF secretion after nerve injury.
Su WF, Wu F, Jin ZH, Gu Y, Chen YT, Fei Y, Chen H, Wang YX, Xing LY, Zhao YY, Yuan Y, Tang X, Chen G
Glia 2019 Jan;67(1):78-90
Glia 2019 Jan;67(1):78-90
Neuroprotective effects of Astilbin on MPTP-induced Parkinson's disease mice: Glial reaction, α-synuclein expression and oxidative stress.
Zhu YL, Sun MF, Jia XB, Cheng K, Xu YD, Zhou ZL, Zhang PH, Qiao CM, Cui C, Chen X, Yang XS, Shen YQ
International immunopharmacology 2019 Jan;66:19-27
International immunopharmacology 2019 Jan;66:19-27
HUS1 checkpoint clamp component (HUS1) is a potential tumor suppressor in primary hepatocellular carcinoma.
Zhou ZQ, Zhao JJ, Chen CL, Liu Y, Zeng JX, Wu ZR, Tang Y, Zhu Q, Weng DS, Xia JC
Molecular carcinogenesis 2019 Jan;58(1):76-87
Molecular carcinogenesis 2019 Jan;58(1):76-87
ERp57‑small interfering RNA silencing can enhance the sensitivity of drug‑resistant human ovarian cancer cells to paclitaxel.
Li S, Zhao X, Chang S, Li Y, Guo M, Guan Y
International journal of oncology 2019 Jan;54(1):249-260
International journal of oncology 2019 Jan;54(1):249-260
MiR-20a Plays a Key Regulatory Role in the Repair of Spinal Cord Dorsal Column Lesion via PDZ-RhoGEF/RhoA/GAP43 Axis in Rat.
Wang T, Li B, Yuan X, Cui L, Wang Z, Zhang Y, Yu M, Xiu Y, Zhang Z, Li W, Wang F, Guo X, Zhao X, Chen X
Cellular and molecular neurobiology 2019 Jan;39(1):87-98
Cellular and molecular neurobiology 2019 Jan;39(1):87-98
Heme oxygenase-1 prevents heart against myocardial infarction by attenuating ischemic injury-induced cardiomyocytes senescence.
Shan H, Li T, Zhang L, Yang R, Li Y, Zhang M, Dong Y, Zhou Y, Xu C, Yang B, Liang H, Gao X, Shan H
EBioMedicine 2019 Jan;39:59-68
EBioMedicine 2019 Jan;39:59-68
DPSCs seeded in acellular nerve grafts processed by Myroilysin improve nerve regeneration.
Qiao W, Lu L, Wu G, An X, Li D, Guo J
Journal of biomaterials applications 2019 Jan;33(6):819-833
Journal of biomaterials applications 2019 Jan;33(6):819-833
Dual regulatory role of CCNA2 in modulating CDK6 and MET-mediated cell-cycle pathway and EMT progression is blocked by miR-381-3p in bladder cancer.
Li J, Ying Y, Xie H, Jin K, Yan H, Wang S, Xu M, Xu X, Wang X, Yang K, Zheng X, Xie L
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 Jan;33(1):1374-1388
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 Jan;33(1):1374-1388
Chromium(VI) promotes cell migration through targeting epithelial-mesenchymal transition in prostate cancer.
Zhang C, Cai K, Feng Q, Xu Y, Zhang Z
Toxicology letters 2019 Jan;300:10-17
Toxicology letters 2019 Jan;300:10-17
MiR-10b suppresses the growth and metastasis of colorectal cancer cell by targeting FGF13.
Song JJ, Li W
European review for medical and pharmacological sciences 2019 Jan;23(2):576-587
European review for medical and pharmacological sciences 2019 Jan;23(2):576-587
Characterization and proteomic profiling of pancreatic cancer-derived serum exosomes.
Jiao YJ, Jin DD, Jiang F, Liu JX, Qu LS, Ni WK, Liu ZX, Lu CH, Ni RZ, Zhu J, Xiao MB
Journal of cellular biochemistry 2019 Jan;120(1):988-999
Journal of cellular biochemistry 2019 Jan;120(1):988-999
Combined detection of estrogen and tumor markers is an important reference factor in the diagnosis and prognosis of lung cancer.
Bai Y, Shen W, Zhu M, Zhang L, Wei Y, Tang H, Zhao J
Journal of cellular biochemistry 2019 Jan;120(1):105-114
Journal of cellular biochemistry 2019 Jan;120(1):105-114
EETs/PPARs activation together mediates the preventive effect of naringenin in high glucose-induced cardiomyocyte hypertrophy.
Zhang J, Qiu H, Huang J, Ding S, Huang B, Zhou P, Jiang Q
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Jan;109:1498-1505
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Jan;109:1498-1505
Ginsenoside Rd contributes the attenuation of cardiac hypertrophy in vivo and in vitro.
Zhang N, An X, Lang P, Wang F, Xie Y
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Jan;109:1016-1023
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Jan;109:1016-1023
Role of bone morphogenetic protein-2/4 in astrocyte activation in neuropathic pain.
Yang L, Liu S, Wang Y
Molecular pain 2019 Jan-Dec;15:1744806919892100
Molecular pain 2019 Jan-Dec;15:1744806919892100
Zingerone Nanotetramer Strengthened the Polypharmacological Efficacy of Zingerone on Human Hepatoma Cell Lines.
Kung ML, Lin PY, Huang ST, Tai MH, Hsieh SL, Wu CC, Yeh BW, Wu WJ, Hsieh S
ACS applied materials & interfaces 2019 Jan 9;11(1):137-150
ACS applied materials & interfaces 2019 Jan 9;11(1):137-150
A scorpion venom peptide Ev37 restricts viral late entry by alkalizing acidic organelles.
Li F, Lang Y, Ji Z, Xia Z, Han Y, Cheng Y, Liu G, Sun F, Zhao Y, Gao M, Chen Z, Wu Y, Li W, Cao Z
The Journal of biological chemistry 2019 Jan 4;294(1):182-194
The Journal of biological chemistry 2019 Jan 4;294(1):182-194
The deregulation of STIM1 and store operative calcium entry impaired aortic smooth muscle cells contractility in aortic medial degeneration.
Hong J, Hu Z, Wu Q, Tang C, Hu J, Chen R, Li B, Wang Z
Bioscience reports 2019 Jan 31;39(1)
Bioscience reports 2019 Jan 31;39(1)
DDX19 Inhibits Type I Interferon Production by Disrupting TBK1-IKKε-IRF3 Interactions and Promoting TBK1 and IKKε Degradation.
Zhang K, Zhang Y, Xue J, Meng Q, Liu H, Bi C, Li C, Hu L, Yu H, Xiong T, Yang Y, Cui S, Bu Z, He X, Li J, Huang L, Weng C
Cell reports 2019 Jan 29;26(5):1258-1272.e4
Cell reports 2019 Jan 29;26(5):1258-1272.e4
Atoh1 Controls Primary Cilia Formation to Allow for SHH-Triggered Granule Neuron Progenitor Proliferation.
Chang CH, Zanini M, Shirvani H, Cheng JS, Yu H, Feng CH, Mercier AL, Hung SY, Forget A, Wang CH, Cigna SM, Lu IL, Chen WY, Leboucher S, Wang WJ, Ruat M, Spassky N, Tsai JW, Ayrault O
Developmental cell 2019 Jan 28;48(2):184-199.e5
Developmental cell 2019 Jan 28;48(2):184-199.e5
The Plk1 kinase negatively regulates the Hedgehog signaling pathway by phosphorylating Gli1.
Zhang T, Xin G, Jia M, Zhuang T, Zhu S, Zhang B, Wang G, Jiang Q, Zhang C
Journal of cell science 2019 Jan 22;132(2)
Journal of cell science 2019 Jan 22;132(2)
Acetaldehyde dehydrogenase 2 interactions with LDLR and AMPK regulate foam cell formation.
Zhong S, Li L, Zhang YL, Zhang L, Lu J, Guo S, Liang N, Ge J, Zhu M, Tao Y, Wu YC, Yin H
The Journal of clinical investigation 2019 Jan 2;129(1):252-267
The Journal of clinical investigation 2019 Jan 2;129(1):252-267
LncRNA SNHG12 inhibits miR-199a to upregulate SIRT1 to attenuate cerebral ischemia/reperfusion injury through activating AMPK signaling pathway.
Yin WL, Yin WG, Huang BS, Wu LX
Neuroscience letters 2019 Jan 18;690:188-195
Neuroscience letters 2019 Jan 18;690:188-195
Sphingosine 1 phosphate receptor-1 (S1P1) promotes tumor-associated regulatory T cell expansion: leading to poor survival in bladder cancer.
Liu YN, Zhang H, Zhang L, Cai TT, Huang DJ, He J, Ni HH, Zhou FJ, Zhang XS, Li J
Cell death & disease 2019 Jan 18;10(2):50
Cell death & disease 2019 Jan 18;10(2):50
Genome-wide CRISPR Analysis Identifies Substrate-Specific Conjugation Modules in ER-Associated Degradation.
Leto DE, Morgens DW, Zhang L, Walczak CP, Elias JE, Bassik MC, Kopito RR
Molecular cell 2019 Jan 17;73(2):377-389.e11
Molecular cell 2019 Jan 17;73(2):377-389.e11
Transfer of Extracellular Vesicle-Associated-RNAs Induces Drug Resistance in ALK-Translocated Lung Adenocarcinoma.
Kwok HH, Ning Z, Chong PW, Wan TS, Ng MH, Ho GYF, Ip MS, Lam DC
Cancers 2019 Jan 17;11(1)
Cancers 2019 Jan 17;11(1)
Cathepsin C promotes microglia M1 polarization and aggravates neuroinflammation via activation of Ca2+-dependent PKC/p38MAPK/NF-κB pathway.
Liu Q, Zhang Y, Liu S, Liu Y, Yang X, Liu G, Shimizu T, Ikenaka K, Fan K, Ma J
Journal of neuroinflammation 2019 Jan 16;16(1):10
Journal of neuroinflammation 2019 Jan 16;16(1):10
Hepatitis B e Antigen Inhibits NF-κB Activity by Interrupting K63-Linked Ubiquitination of NEMO.
Wang Y, Cui L, Yang G, Zhan J, Guo L, Chen Y, Fan C, Liu D, Guo D
Journal of virology 2019 Jan 15;93(2)
Journal of virology 2019 Jan 15;93(2)
Binding of cellular nucleolin with the viral core RNA G-quadruplex structure suppresses HCV replication.
Bian WX, Xie Y, Wang XN, Xu GH, Fu BS, Li S, Long G, Zhou X, Zhang XL
Nucleic acids research 2019 Jan 10;47(1):56-68
Nucleic acids research 2019 Jan 10;47(1):56-68
N6-methyladenosine modification and METTL3 modulate enterovirus 71 replication.
Hao H, Hao S, Chen H, Chen Z, Zhang Y, Wang J, Wang H, Zhang B, Qiu J, Deng F, Guan W
Nucleic acids research 2019 Jan 10;47(1):362-374
Nucleic acids research 2019 Jan 10;47(1):362-374
Histone Demethylase KDM4B Promotes DNA Damage by Activating Long Interspersed Nuclear Element-1.
Xiang Y, Yan K, Zheng Q, Ke H, Cheng J, Xiong W, Shi X, Wei L, Zhao M, Yang F, Wang P, Lu X, Fu L, Lu X, Li F
Cancer research 2019 Jan 1;79(1):86-98
Cancer research 2019 Jan 1;79(1):86-98
FAPP2 promotes tumor cell growth in human colon cancer through activation of Wnt signaling.
Chen J, Li L, Zhou Z, Yu S, Li Y, Gao Y
Experimental cell research 2019 Jan 1;374(1):12-18
Experimental cell research 2019 Jan 1;374(1):12-18
Piezo1 mediates angiogenesis through activation of MT1-MMP signaling.
Kang H, Hong Z, Zhong M, Klomp J, Bayless KJ, Mehta D, Karginov AV, Hu G, Malik AB
American journal of physiology. Cell physiology 2019 Jan 1;316(1):C92-C103
American journal of physiology. Cell physiology 2019 Jan 1;316(1):C92-C103
Different Isoforms of the Neuronal Guidance Molecule Slit2 Directly Cause Chemoattraction or Chemorepulsion of Human Neutrophils.
Pilling D, Chinea LE, Consalvo KM, Gomer RH
Journal of immunology (Baltimore, Md. : 1950) 2019 Jan 1;202(1):239-248
Journal of immunology (Baltimore, Md. : 1950) 2019 Jan 1;202(1):239-248
MiR-26a-5p Inhibits Cell Proliferation and Enhances Doxorubicin Sensitivity in HCC Cells via Targeting AURKA.
Yuan YL, Yu H, Mu SM, Dong YD, Li Y
Technology in cancer research & treatment 2019 Jan 1;18:1533033819851833
Technology in cancer research & treatment 2019 Jan 1;18:1533033819851833
Colon Cancer Cell Secretes EGF to Promote M2 Polarization of TAM Through EGFR/PI3K/AKT/mTOR Pathway.
Lian G, Chen S, Ouyang M, Li F, Chen L, Yang J
Technology in cancer research & treatment 2019 Jan 1;18:1533033819849068
Technology in cancer research & treatment 2019 Jan 1;18:1533033819849068
MMP13 inhibition rescues cognitive decline in Alzheimer transgenic mice via BACE1 regulation.
Zhu BL, Long Y, Luo W, Yan Z, Lai YJ, Zhao LG, Zhou WH, Wang YJ, Shen LL, Liu L, Deng XJ, Wang XF, Sun F, Chen GJ
Brain : a journal of neurology 2019 Jan 1;142(1):176-192
Brain : a journal of neurology 2019 Jan 1;142(1):176-192
Genotoxic stress causes the accumulation of DNA-dependent protein kinase catalytic subunit phosphorylated at serine 2056 at nuclear speckles and alters pre-mRNA alternative splicing.
Liu S, Shao Y, Wang Q, Zhai Y, Li X
FEBS open bio 2019 Feb;9(2):304-314
FEBS open bio 2019 Feb;9(2):304-314
High expression of SLC17A9 correlates with poor prognosis in colorectal cancer.
Yang L, Chen Z, Xiong W, Ren H, Zhai E, Xu K, Yang H, Zhang Z, Ding L, He Y, Song X, Liu J
Human pathology 2019 Feb;84:62-70
Human pathology 2019 Feb;84:62-70
MicroRNA-5195-3p plays a suppressive role in cell proliferation, migration and invasion by targeting MYO6 in human non-small cell lung cancer.
Yang Q
Bioscience, biotechnology, and biochemistry 2019 Feb;83(2):212-220
Bioscience, biotechnology, and biochemistry 2019 Feb;83(2):212-220
Early onset developmental delay and epilepsy in pediatric patients with WDR45 variants.
Chen H, Qian Y, Yu S, Xiao D, Guo X, Wang Q, Hao L, Yan K, Lu Y, Dong X, Zhou W, Wu B, Zhou S, Wang H
European journal of medical genetics 2019 Feb;62(2):149-160
European journal of medical genetics 2019 Feb;62(2):149-160
Tunicamycin enhances the suppressive effects of cisplatin on lung cancer growth through PTX3 glycosylation via AKT/NF-κB signaling pathway.
Ahmmed B, Khan MN, Nisar MA, Kampo S, Zheng Q, Li Y, Yan Q
International journal of oncology 2019 Feb;54(2):431-442
International journal of oncology 2019 Feb;54(2):431-442
Increased levels of serum pigment epithelium-derived factor aggravate proteinuria via induction of podocyte actin rearrangement.
Huang N, Zhang X, Jiang Y, Mei H, Zhang L, Zhang Q, Hu J, Chen B
International urology and nephrology 2019 Feb;51(2):359-367
International urology and nephrology 2019 Feb;51(2):359-367
Rapid depletion of ESCRT protein Vps4 underlies injury-induced autophagic impediment and Wallerian degeneration.
Wang H, Wang X, Zhang K, Wang Q, Cao X, Wang Z, Zhang S, Li A, Liu K, Fang Y
Science advances 2019 Feb;5(2):eaav4971
Science advances 2019 Feb;5(2):eaav4971
CXCR4 enhances cisplatin resistance of human tongue squamous cell carcinoma.
Zhuang XM, Zhou B
Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology 2019 Feb;48(2):122-128
Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology 2019 Feb;48(2):122-128
Chlamydia trachomatis plasmid-encoded protein Pgp3 inhibits apoptosis via the PI3K-AKT-mediated MDM2-p53 axis.
Zou Y, Lei W, Su S, Bu J, Zhu S, Huang Q, Li Z
Molecular and cellular biochemistry 2019 Feb;452(1-2):167-176
Molecular and cellular biochemistry 2019 Feb;452(1-2):167-176
The Effects of Mitogen-activated Protein Kinase Signaling Pathways on Lipopolysaccharide-mediated Osteo/Odontogenic Differentiation of Stem Cells from the Apical Papilla.
Liu J, Du J, Chen X, Yang L, Zhao W, Song M, Wang Z, Wang Y
Journal of endodontics 2019 Feb;45(2):161-167
Journal of endodontics 2019 Feb;45(2):161-167
Down-regulation of lncRNA OGFRP1 induces autophagy and growth inhibition by AKT/mTOR signaling pathway in HCAECs.
Zhang X, Liu J, Gu Y, Sun C, Qu F
Cell biology international 2019 Feb;43(2):158-166
Cell biology international 2019 Feb;43(2):158-166
Investigating a chimeric anti-mouse PDGFRα antibody as a radiosensitizer in primary mouse sarcomas.
Song EJ, Ashcraft KA, Lowery CD, Mowery YM, Luo L, Ma Y, Campos LDS, Cardona DM, Stancato L, Kirsch DG
EBioMedicine 2019 Feb;40:224-230
EBioMedicine 2019 Feb;40:224-230
Antiviral activity of bone morphogenetic proteins and activins.
Eddowes LA, Al-Hourani K, Ramamurthy N, Frankish J, Baddock HT, Sandor C, Ryan JD, Fusco DN, Arezes J, Giannoulatou E, Boninsegna S, Chevaliez S, Owens BMJ, Sun CC, Fabris P, Giordani MT, Martines D, Vukicevic S, Crowe J, Lin HY, Rehwinkel J, McHugh PJ, Binder M, Babitt JL, Chung RT, Lawless MW, Armitage AE, Webber C, Klenerman P, Drakesmith H
Nature microbiology 2019 Feb;4(2):339-351
Nature microbiology 2019 Feb;4(2):339-351
Decrease of GSK3β Ser-9 Phosphorylation Induced Osteoblast Apoptosis in Rat Osteoarthritis Model.
Deng S, Nie ZG, Peng PJ, Liu Y, Xing S, Long LS, Peng H
Current medical science 2019 Feb;39(1):75-80
Current medical science 2019 Feb;39(1):75-80
Acetylation of AGO2 promotes cancer progression by increasing oncogenic miR-19b biogenesis.
Zhang H, Wang Y, Dou J, Guo Y, He J, Li L, Liu X, Chen R, Deng R, Huang J, Xie R, Zhao X, Yu J
Oncogene 2019 Feb;38(9):1410-1431
Oncogene 2019 Feb;38(9):1410-1431
Lipopolysaccharide from Escherichia coli stimulates osteogenic differentiation of human periodontal ligament stem cells through Wnt/β-catenin-induced TAZ elevation.
Xing Y, Zhang Y, Jia L, Xu X
Molecular oral microbiology 2019 Feb;34(1)
Molecular oral microbiology 2019 Feb;34(1)
Drastic induction of MMP-7 by cortisol in the human amnion: implications for membrane rupture at parturition.
Wang LY, Wang WS, Wang YW, Lu JW, Lu Y, Zhang CY, Li WJ, Sun K, Ying H
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 Feb;33(2):2770-2781
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 Feb;33(2):2770-2781
Bisphenol A exposure alters placentation and causes preeclampsia-like features in pregnant mice involved in reprogramming of DNA methylation of WNT2.
Ye Y, Tang Y, Xiong Y, Feng L, Li X
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 Feb;33(2):2732-2742
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 Feb;33(2):2732-2742
PPPDE1 promotes hepatocellular carcinoma development by negatively regulate p53 and apoptosis.
Xie X, Wang X, Liao W, Fei R, Wu N, Cong X, Chen Q, Wei L, Wang Y, Chen H
Apoptosis : an international journal on programmed cell death 2019 Feb;24(1-2):135-144
Apoptosis : an international journal on programmed cell death 2019 Feb;24(1-2):135-144
Otx2 enhances transdifferentiation of Müller cells-derived retinal stem cells into photoreceptor-like cells.
Xiong Y, Ji H, You Z, Yao F, Zhou R, Song W, Xia X
Journal of cellular and molecular medicine 2019 Feb;23(2):943-953
Journal of cellular and molecular medicine 2019 Feb;23(2):943-953
Phorbol esters induce PLVAP expression via VEGF and additional secreted molecules in MEK1-dependent and p38, JNK and PI3K/Akt-independent manner.
Hamilton BJ, Tse D, Stan RV
Journal of cellular and molecular medicine 2019 Feb;23(2):920-933
Journal of cellular and molecular medicine 2019 Feb;23(2):920-933
Nucleoporin 107 facilitates the nuclear export of Scn5a mRNA to regulate cardiac bioelectricity.
Guan Y, Gao X, Tang Q, Huang L, Gao S, Yu S, Huang J, Li J, Zhou D, Zhang Y, Shi D, Liang D, Liu Y, Li L, Cui Y, Xu L, Chen YH
Journal of cellular and molecular medicine 2019 Feb;23(2):1448-1457
Journal of cellular and molecular medicine 2019 Feb;23(2):1448-1457
Glucose Signaling Is Connected to Chromosome Segregation Through Protein Kinase A Phosphorylation of the Dam1 Kinetochore Subunit in Saccharomyces cerevisiae.
Shah SB, Parmiter D, Constantine C, Elizalde P, Naldrett M, Karpova TS, Choy JS
Genetics 2019 Feb;211(2):531-547
Genetics 2019 Feb;211(2):531-547
Endogenous cholesterol ester hydroperoxides modulate cholesterol levels and inhibit cholesterol uptake in hepatocytes and macrophages.
Guo S, Lu J, Zhuo Y, Xiao M, Xue X, Zhong S, Shen X, Yin C, Li L, Chen Q, Zhu M, Chen B, Zhao M, Zheng L, Tao Y, Yin H
Redox biology 2019 Feb;21:101069
Redox biology 2019 Feb;21:101069
Proteomic Profiling of LPS-Induced Macrophage-Derived Exosomes Indicates Their Involvement in Acute Liver Injury.
Wang G, Jin S, Ling X, Li Y, Hu Y, Zhang Y, Huang Y, Chen T, Lin J, Ning Z, Meng Y, Li X
Proteomics 2019 Feb;19(3):e1800274
Proteomics 2019 Feb;19(3):e1800274
miR-140-5p inhibits cell proliferation and invasion in colorectal carcinoma by targeting SOX4.
Zhao Z, Liu W, Li J
Oncology letters 2019 Feb;17(2):2215-2220
Oncology letters 2019 Feb;17(2):2215-2220
miR-7-5p inhibits cell migration and invasion in glioblastoma through targeting SATB1.
Yin CY, Kong W, Jiang J, Xu H, Zhao W
Oncology letters 2019 Feb;17(2):1819-1825
Oncology letters 2019 Feb;17(2):1819-1825
Ebselen protects rat hearts against myocardial ischemia-reperfusion injury.
Cheng B, Zhong JP, Wu FX, Li GL, Ruan QX, Luo G, Jiang H
Experimental and therapeutic medicine 2019 Feb;17(2):1412-1419
Experimental and therapeutic medicine 2019 Feb;17(2):1412-1419
Motor Neuron Abnormalities Correlate with Impaired Movement in Zebrafish that Express Mutant Superoxide Dismutase 1.
Robinson KJ, Yuan KC, Don EK, Hogan AL, Winnick CG, Tym MC, Lucas CW, Shahheydari H, Watchon M, Blair IP, Atkin JD, Nicholson GA, Cole NJ, Laird AS
Zebrafish 2019 Feb;16(1):8-14
Zebrafish 2019 Feb;16(1):8-14
Doxorubicin conjugated with nanodiamonds and in free form commit glioblastoma cells to heterodromous fates.
Chen Z, Wang C, Li TF, Li K, Yue Y, Liu X, Xu HZ, Wen Y, Zhang Q, Han M, Komatsu N, Xu YH, Zhao L, Chen X
Nanomedicine (London, England) 2019 Feb;14(3):335-351
Nanomedicine (London, England) 2019 Feb;14(3):335-351
Coupling function of cyclin-dependent kinase 2 and Septin2 in the promotion of hepatocellular carcinoma.
Xu C, Zhang W, Zhang X, Zhou D, Qu L, Liu J, Xiao M, Ni R, Jiang F, Ni W, Lu C
Cancer science 2019 Feb;110(2):540-549
Cancer science 2019 Feb;110(2):540-549
MiR-23a-3p acts as an oncogene and potential prognostic biomarker by targeting PNRC2 in RCC.
Quan J, Pan X, Li Y, Hu Y, Tao L, Li Z, Zhao L, Wang J, Li H, Lai Y, Zhou L, Lin C, Gui Y, Ye J, Zhang F, Lai Y
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Feb;110:656-666
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Feb;110:656-666
Long non-coding RNA SNHG6 enhances cell proliferation, migration and invasion by regulating miR-26a-5p/MAPK6 in breast cancer.
Lv P, Qiu X, Gu Y, Yang X, Xu X, Yang Y
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Feb;110:294-301
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Feb;110:294-301
Noradrenergic depletion causes sex specific alterations in the endocannabinoid system in the Murine prefrontal cortex.
Urquhart MA, Ross JA, Reyes BAS, Nitikman M, Thomas SA, Mackie K, Van Bockstaele EJ
Neurobiology of stress 2019 Feb;10:100164
Neurobiology of stress 2019 Feb;10:100164
Combined Single-Cell Profiling of lncRNAs and Functional Screening Reveals that H19 Is Pivotal for Embryonic Hematopoietic Stem Cell Development.
Zhou J, Xu J, Zhang L, Liu S, Ma Y, Wen X, Hao J, Li Z, Ni Y, Li X, Zhou F, Li Q, Wang F, Wang X, Si Y, Zhang P, Liu C, Bartolomei M, Tang F, Liu B, Yu J, Lan Y
Cell stem cell 2019 Feb 7;24(2):285-298.e5
Cell stem cell 2019 Feb 7;24(2):285-298.e5
SNHG1 promotes malignant biological behaviors of glioma cells via microRNA-154-5p/miR-376b-3p- FOXP2- KDM5B participating positive feedback loop.
Li H, Xue Y, Ma J, Shao L, Wang D, Zheng J, Liu X, Yang C, He Q, Ruan X, Li Z, Liu Y
Journal of experimental & clinical cancer research : CR 2019 Feb 6;38(1):59
Journal of experimental & clinical cancer research : CR 2019 Feb 6;38(1):59
Increased expression of thymic stromal lymphopoietin receptor in a rat model of middle cerebral artery occlusion.
Yu X, Zeng K, Liu X, Peng Y, Li C, Fu K, Liang H
Neuroreport 2019 Feb 6;30(3):182-187
Neuroreport 2019 Feb 6;30(3):182-187
Heterozygous Tbk1 loss has opposing effects in early and late stages of ALS in mice.
Brenner D, Sieverding K, Bruno C, Lüningschrör P, Buck E, Mungwa S, Fischer L, Brockmann SJ, Ulmer J, Bliederhäuser C, Philibert CE, Satoh T, Akira S, Boillée S, Mayer B, Sendtner M, Ludolph AC, Danzer KM, Lobsiger CS, Freischmidt A, Weishaupt JH
The Journal of experimental medicine 2019 Feb 4;216(2):267-278
The Journal of experimental medicine 2019 Feb 4;216(2):267-278
LPCAT1 promotes brain metastasis of lung adenocarcinoma by up-regulating PI3K/AKT/MYC pathway.
Wei C, Dong X, Lu H, Tong F, Chen L, Zhang R, Dong J, Hu Y, Wu G, Dong X
Journal of experimental & clinical cancer research : CR 2019 Feb 21;38(1):95
Journal of experimental & clinical cancer research : CR 2019 Feb 21;38(1):95
High-fat and high-glucose microenvironment decreases Runx2 and TAZ expression and inhibits bone regeneration in the mouse.
Wu X, Zhang Y, Xing Y, Zhao B, Zhou C, Wen Y, Xu X
Journal of orthopaedic surgery and research 2019 Feb 18;14(1):55
Journal of orthopaedic surgery and research 2019 Feb 18;14(1):55
Novel metabolic disorders in skeletal muscle of Lipodystrophic Bscl2/Seipin deficient mice.
Xu W, Zhou H, Xuan H, Saha P, Wang G, Chen W
Molecular and cellular endocrinology 2019 Feb 15;482:1-10
Molecular and cellular endocrinology 2019 Feb 15;482:1-10
Curcumae Radix Extract Decreases Mammary Tumor-Derived Lung Metastasis via Suppression of C-C Chemokine Receptor Type 7 Expression.
Kaya P, Lee SR, Lee YH, Kwon SW, Yang H, Lee HW, Hong EJ
Nutrients 2019 Feb 15;11(2)
Nutrients 2019 Feb 15;11(2)
Involvement of serum amyloid A1 in the rupture of fetal membranes through induction of collagen I degradation.
Wang WS, Li WJ, Wang YW, Wang LY, Mi YB, Lu JW, Lu Y, Zhang CY, Sun K
Clinical science (London, England : 1979) 2019 Feb 14;133(3):515-530
Clinical science (London, England : 1979) 2019 Feb 14;133(3):515-530
NLRC3 inhibits MCT-induced pulmonary hypertension in rats via attenuating PI3K activation.
Zha LH, Zhou J, Li TZ, Luo H, Zhang MQ, Li S, Yu ZX
Journal of cellular physiology 2019 Feb 14;
Journal of cellular physiology 2019 Feb 14;
Long non-coding RNA FAM84B-AS promotes resistance of gastric cancer to platinum drugs through inhibition of FAM84B expression.
Zhang Y, Li Q, Yu S, Zhu C, Zhang Z, Cao H, Xu J
Biochemical and biophysical research communications 2019 Feb 12;509(3):753-762
Biochemical and biophysical research communications 2019 Feb 12;509(3):753-762
Ankyrin-G regulated epithelial phenotype is required for mouse lens morphogenesis and growth.
Rasiah PK, Maddala R, Bennett V, Rao PV
Developmental biology 2019 Feb 1;446(1):119-131
Developmental biology 2019 Feb 1;446(1):119-131
Fragment-based drug discovery of triazole inhibitors to block PDEδ-RAS protein-protein interaction.
Chen D, Chen Y, Lian F, Chen L, Li Y, Cao D, Wang X, Chen L, Li J, Meng T, Huang M, Geng M, Shen J, Zhang N, Xiong B
European journal of medicinal chemistry 2019 Feb 1;163:597-609
European journal of medicinal chemistry 2019 Feb 1;163:597-609
Host HDAC4 regulates the antiviral response by inhibiting the phosphorylation of IRF3.
Yang Q, Tang J, Pei R, Gao X, Guo J, Xu C, Wang Y, Wang Q, Wu C, Zhou Y, Hu X, Zhao H, Wang Y, Chen X, Chen J
Journal of molecular cell biology 2019 Feb 1;11(2):158-169
Journal of molecular cell biology 2019 Feb 1;11(2):158-169
MiR-26b suppresses hepatocellular carcinoma development by negatively regulating ZNRD1 and Wnt/β-catenin signaling.
Hu X, Wang R, Ren Z, Liu X, Gu J, Cui G, Li Q
Cancer medicine 2019 Dec;8(17):7359-7371
Cancer medicine 2019 Dec;8(17):7359-7371
Upregulation of CYP2E1 expression causes oxidative damage induced by 2-chloroethanol in primary cultured rat astrocytes.
Tang H, Sun Q, Wang T, Liao Y, Wang G, Zhao F, Jin Y
Neurotoxicology 2019 Dec;75:233-244
Neurotoxicology 2019 Dec;75:233-244
Bioactive molecule Icariin inhibited proliferation while enhanced apoptosis and autophagy of rat airway smooth muscle cells in vitro.
Yang L, Xiao B, Hou L, Zhou G, Mo B, Yao D
Cytotechnology 2019 Dec;71(6):1109-1120
Cytotechnology 2019 Dec;71(6):1109-1120
Upregulated Expression of CUX1 Correlates with Poor Prognosis in Glioma Patients: a Bioinformatic Analysis.
Wu X, Feng F, Yang C, Zhang M, Cheng Y, Zhao Y, Wang Y, Che F, Zhang J, Heng X
Journal of molecular neuroscience : MN 2019 Dec;69(4):527-537
Journal of molecular neuroscience : MN 2019 Dec;69(4):527-537
Molecular mechanism of Bisphenol A on androgen receptor antagonism.
Huang X, Cang X, Liu J
Toxicology in vitro : an international journal published in association with BIBRA 2019 Dec;61:104621
Toxicology in vitro : an international journal published in association with BIBRA 2019 Dec;61:104621
miR-124 ameliorates depressive-like behavior by targeting STAT3 to regulate microglial activation.
Lou D, Wang J, Wang X
Molecular and cellular probes 2019 Dec;48:101470
Molecular and cellular probes 2019 Dec;48:101470
Ribociclib (LEE011) suppresses cell proliferation and induces apoptosis of MDA-MB-231 by inhibiting CDK4/6-cyclin D-Rb-E2F pathway.
Li T, Xiong Y, Wang Q, Chen F, Zeng Y, Yu X, Wang Y, Zhou F, Zhou Y
Artificial cells, nanomedicine, and biotechnology 2019 Dec;47(1):4001-4011
Artificial cells, nanomedicine, and biotechnology 2019 Dec;47(1):4001-4011
Cancer cell membrane cloaking nanoparticles for targeted co-delivery of doxorubicin and PD-L1 siRNA.
Chen M, Chen M, He J
Artificial cells, nanomedicine, and biotechnology 2019 Dec;47(1):1635-1641
Artificial cells, nanomedicine, and biotechnology 2019 Dec;47(1):1635-1641
Palmitoylome profiling indicates that androgens regulate the palmitoylation of α‑tubulin in prostate cancer‑derived LNCaP cells and supernatants.
Li W, Zhang J, Zou L, Cui J, Su F, Jin J, Xiao F, Liu M, Zhao G
Oncology reports 2019 Dec;42(6):2788-2796
Oncology reports 2019 Dec;42(6):2788-2796
Intrathecal injection of dexmedetomidine ameliorates chronic neuropathic pain via the modulation of MPK3/ERK1/2 in a mouse model of chronic neuropathic pain.
Qian Y, Wang Q, Jiao J, Wang G, Gu Z, Huang D, Wang Z
Neurological research 2019 Dec;41(12):1059-1068
Neurological research 2019 Dec;41(12):1059-1068
Mebendazole elicits potent antimyeloma activity by inhibiting the USP5/c-Maf axis.
Chen XH, Xu YJ, Wang XG, Lin P, Cao BY, Zeng YY, Wang Q, Zhang ZB, Mao XL, Zhang T
Acta pharmacologica Sinica 2019 Dec;40(12):1568-1577
Acta pharmacologica Sinica 2019 Dec;40(12):1568-1577
Epigenetic regulation of TIMP1 expression by 8-oxoguanine DNA glycosylase-1 binding to DNA:RNA hybrid.
Pan L, Wang H, Luo J, Zeng J, Pi J, Liu H, Liu C, Ba X, Qu X, Xiang Y, Boldogh I, Qin X
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 Dec;33(12):14159-14170
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 Dec;33(12):14159-14170
Silencing ubiquitin-conjugating enzyme 2C inhibits proliferation and epithelial-mesenchymal transition in pancreatic ductal adenocarcinoma.
Wang X, Yin L, Yang L, Zheng Y, Liu S, Yang J, Cui H, Wang H
The FEBS journal 2019 Dec;286(24):4889-4909
The FEBS journal 2019 Dec;286(24):4889-4909
Rotenone protects against β-cell apoptosis and attenuates type 1 diabetes mellitus.
Wu M, Chen W, Zhang S, Huang S, Zhang A, Zhang Y, Jia Z
Apoptosis : an international journal on programmed cell death 2019 Dec;24(11-12):879-891
Apoptosis : an international journal on programmed cell death 2019 Dec;24(11-12):879-891
STRIP2 silencing inhibits vascular smooth muscle cell proliferation and migration via P38-AKT-MMP-2 signaling pathway.
Dai L, Zhou J, Li T, Qian Y, Jin L, Zhu C, Li S
Journal of cellular physiology 2019 Dec;234(12):22463-22476
Journal of cellular physiology 2019 Dec;234(12):22463-22476
HOXC13-AS promotes breast cancer cell growth through regulating miR-497-5p/PTEN axis.
Li X, Wang Q, Rui Y, Zhang C, Wang W, Gu J, Tang J, Ding Y
Journal of cellular physiology 2019 Dec;234(12):22343-22351
Journal of cellular physiology 2019 Dec;234(12):22343-22351
Integrated analysis of transcriptome data revealed MMP3 and MMP13 as critical genes in anaplastic thyroid cancer progression.
Ma Y, Cang S, Li G, Su Y, Zhang H, Wang L, Yang J, Shi X, Qin G, Yuan H
Journal of cellular physiology 2019 Dec;234(12):22260-22271
Journal of cellular physiology 2019 Dec;234(12):22260-22271
Critical roles of PI3K/Akt/NF‑κB survival axis in angiotensin II‑induced podocyte injury.
Wang J, Fu D, Senouthai S, You Y
Molecular medicine reports 2019 Dec;20(6):5134-5144
Molecular medicine reports 2019 Dec;20(6):5134-5144
PTEN-knockdown disrupts the morphology, growth pattern and function of Nthy-Ori 3-1 cells by downregulating PAX8 expression.
Sun Z, Lu J, Wu M, Ouyang C, Xing Y, Hou X, Shi Z, Wu Y
Oncology letters 2019 Dec;18(6):6732-6740
Oncology letters 2019 Dec;18(6):6732-6740
Receptor tyrosine kinase expression in high-grade gliomas before and after chemoradiotherapy.
Wang K, Huang R, Wu C, Li G, Zhao Z, Hu H, Liu Y
Oncology letters 2019 Dec;18(6):6509-6515
Oncology letters 2019 Dec;18(6):6509-6515
Caffeic acid reduces A53T α-synuclein by activating JNK/Bcl-2-mediated autophagy in vitro and improves behaviour and protects dopaminergic neurons in a mouse model of Parkinson's disease.
Zhang Y, Wu Q, Zhang L, Wang Q, Yang Z, Liu J, Feng L
Pharmacological research 2019 Dec;150:104538
Pharmacological research 2019 Dec;150:104538
Identification of viral SIM-SUMO2-interaction inhibitors for treating primary effusion lymphoma.
Ding L, Zhu Q, Zhou F, Tan H, Xu W, Pan C, Zhu C, Wang Y, Zhang H, Fu W, Qian Z, Yuan Z, Xu H, Wei F, Cai Q
PLoS pathogens 2019 Dec;15(12):e1008174
PLoS pathogens 2019 Dec;15(12):e1008174
Genetic ablation and pharmacological inhibition of immunosubunit β5i attenuates cardiac remodeling in deoxycorticosterone-acetate (DOCA)-salt hypertensive mice.
Cao HJ, Fang J, Zhang YL, Zou LX, Han X, Yang J, Yan X, Li PB, Wang HX, Guo SB, Li HH
Journal of molecular and cellular cardiology 2019 Dec;137:34-45
Journal of molecular and cellular cardiology 2019 Dec;137:34-45
16 T high static magnetic field inhibits receptor activator of nuclear factor kappa-Β ligand-induced osteoclast differentiation by regulating iron metabolism in Raw264.7 cells.
Dong D, Yang J, Zhang G, Huyan T, Shang P
Journal of tissue engineering and regenerative medicine 2019 Dec;13(12):2181-2190
Journal of tissue engineering and regenerative medicine 2019 Dec;13(12):2181-2190
Snail2 induced E-cadherin suppression and metastasis in lung carcinoma facilitated by G9a and HDACs.
Hu Y, Zheng Y, Dai M, Wu J, Yu B, Zhang H, Kong W, Wu H, Yu X
Cell adhesion & migration 2019 Dec;13(1):285-292
Cell adhesion & migration 2019 Dec;13(1):285-292
Platelet endothelial aggregation receptor-1 regulates bovine muscle satellite cell migration and differentiation via integrin beta-1 and focal adhesion kinase.
Pang Y, Zhang Z, Wang Z, Wang Y, Yan Y, Li S, Tong H
Cell adhesion & migration 2019 Dec;13(1):192-202
Cell adhesion & migration 2019 Dec;13(1):192-202
Down-regulated long non-coding RNA PVT1 contributes to gestational diabetes mellitus and preeclampsia via regulation of human trophoblast cells.
Wang Q, Lu X, Li C, Zhang W, Lv Y, Wang L, Wu L, Meng L, Fan Y, Ding H, Long W, Lv M
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Dec;120:109501
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Dec;120:109501
Epigallocatechin-3-gallate inhibits tumor angiogenesis: involvement of endoglin/Smad1 signaling in human umbilical vein endothelium cells.
Chen CY, Lin YJ, Wang CCN, Lan YH, Lan SJ, Sheu MJ
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Dec;120:109491
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Dec;120:109491
Ferulic acid increases intestinal Lactobacillus and improves cardiac function in TAC mice.
Liu Z, Ma Z, Zhang H, Summah BS, Liu H, An D, Zhan Q, Lai W, Zeng Q, Ren H, Xu D
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Dec;120:109482
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Dec;120:109482
Endocytic degradation of ErbB2 mediates the effectiveness of neratinib in the suppression of ErbB2-positive ovarian cancer.
Wang S, Zhang J, Wang T, Ren F, Liu X, Lu Y, Xu L, Zhang Y, Wang D, Xu L, Wu Y, Liu F, Li Q, Zaky MY, Liu S, Dong W, Liu F, Zou K, Zhang Y
The international journal of biochemistry & cell biology 2019 Dec;117:105640
The international journal of biochemistry & cell biology 2019 Dec;117:105640
Forkhead box C1 promotes metastasis and invasion of non-small cell lung cancer by binding directly to the lysyl oxidase promoter.
Gong R, Lin W, Gao A, Liu Y, Li J, Sun M, Chen X, Han S, Men C, Sun Y, Liu J
Cancer science 2019 Dec;110(12):3663-3676
Cancer science 2019 Dec;110(12):3663-3676
Dietary Antioxidant Trans-Cinnamaldehyde Reduced Visfatin-Induced Breast Cancer Progression: In Vivo and In Vitro Study.
Chiang YF, Chen HY, Huang KC, Lin PH, Hsia SM
Antioxidants (Basel, Switzerland) 2019 Dec 6;8(12)
Antioxidants (Basel, Switzerland) 2019 Dec 6;8(12)
Rice Protein Exerts Anti-Inflammatory Effect in Growing and Adult Rats via Suppressing NF-κB Pathway.
Wang Z, Liang M, Li H, Cai L, Yang L
International journal of molecular sciences 2019 Dec 6;20(24)
International journal of molecular sciences 2019 Dec 6;20(24)
Role of linc00174/miR-138-5p (miR-150-5p)/FOSL2 Feedback Loop on Regulating the Blood-Tumor Barrier Permeability.
Guo J, Shen S, Liu X, Ruan X, Zheng J, Liu Y, Liu L, Ma J, Ma T, Shao L, Wang D, Yang C, Xue Y
Molecular therapy. Nucleic acids 2019 Dec 6;18:1072-1090
Molecular therapy. Nucleic acids 2019 Dec 6;18:1072-1090
Grape Seed Proanthocyanidins Induce Autophagy and Modulate Survivin in HepG2 Cells and Inhibit Xenograft Tumor Growth in Vivo.
Wang L, Huang W, Zhan J
Nutrients 2019 Dec 6;11(12)
Nutrients 2019 Dec 6;11(12)
NOS1 inhibits the interferon response of cancer cells by S-nitrosylation of HDAC2.
Xu P, Ye S, Li K, Huang M, Wang Q, Zeng S, Chen X, Gao W, Chen J, Zhang Q, Zhong Z, Lin Y, Rong Z, Xu Y, Hao B, Peng A, Ouyang M, Liu Q
Journal of experimental & clinical cancer research : CR 2019 Dec 5;38(1):483
Journal of experimental & clinical cancer research : CR 2019 Dec 5;38(1):483
Astragaloside IV protects against diabetic nephropathy via activating eNOS in streptozotocin diabetes-induced rats.
Fan Y, Fan H, Zhu B, Zhou Y, Liu Q, Li P
BMC complementary and alternative medicine 2019 Dec 5;19(1):355
BMC complementary and alternative medicine 2019 Dec 5;19(1):355
Celastrol Inhibits Dopaminergic Neuronal Death of Parkinson's Disease through Activating Mitophagy.
Lin MW, Lin CC, Chen YH, Yang HB, Hung SY
Antioxidants (Basel, Switzerland) 2019 Dec 31;9(1)
Antioxidants (Basel, Switzerland) 2019 Dec 31;9(1)
Liver Soluble Epoxide Hydrolase Regulates Behavioral and Cellular Effects of Chronic Stress.
Qin XH, Wu Z, Dong JH, Zeng YN, Xiong WC, Liu C, Wang MY, Zhu MZ, Chen WJ, Zhang Y, Huang QY, Zhu XH
Cell reports 2019 Dec 3;29(10):3223-3234.e6
Cell reports 2019 Dec 3;29(10):3223-3234.e6
BMP10 preserves cardiac function through its dual activation of SMAD-mediated and STAT3-mediated pathways.
Qu X, Liu Y, Cao D, Chen J, Liu Z, Ji H, Chen Y, Zhang W, Zhu P, Xiao D, Li X, Shou W, Chen H
The Journal of biological chemistry 2019 Dec 27;294(52):19877-19888
The Journal of biological chemistry 2019 Dec 27;294(52):19877-19888
The regulatory effect of microRNA-21a-3p on the promotion of telocyte angiogenesis mediated by PI3K (p110α)/AKT/mTOR in LPS induced mice ARDS.
Zhou Y, Yang Y, Liang T, Hu Y, Tang H, Song D, Fang H
Journal of translational medicine 2019 Dec 26;17(1):427
Journal of translational medicine 2019 Dec 26;17(1):427
Antiviral activity of interleukin-11 as a response to porcine epidemic diarrhea virus infection.
Li Y, Wu Q, Jin Y, Yang Q
Veterinary research 2019 Dec 21;50(1):111
Veterinary research 2019 Dec 21;50(1):111
Integrated Metabolomics and Network Pharmacology Strategy-Driven Active Traditional Chinese Medicine Ingredients Discovery for the Alleviation of Cisplatin Nephrotoxicity.
Xu L, Zhang Y, Zhang P, Dai X, Gao Y, Lv Y, Qin S, Xu F
Chemical research in toxicology 2019 Dec 16;32(12):2411-2421
Chemical research in toxicology 2019 Dec 16;32(12):2411-2421
Hypothalamic paraventricular nucleus neurons activated by estrogen GPER1 receptors promote anti-inflammation effects in the early stage of colitis.
Jiang T, Wang R, Yin W, Zhou Y, Kong D, Xu S, Gao P, Yu W, Jiao Y, Wen D
Acta biochimica et biophysica Sinica 2019 Dec 13;51(12):1216-1222
Acta biochimica et biophysica Sinica 2019 Dec 13;51(12):1216-1222
The Human Cytomegalovirus Nonstructural Glycoprotein UL148 Reorganizes the Endoplasmic Reticulum.
Zhang H, Read C, Nguyen CC, Siddiquey MNA, Shang C, Hall CM, von Einem J, Kamil JP
mBio 2019 Dec 10;10(6)
mBio 2019 Dec 10;10(6)
The Combination of Adipose-derived Schwann-like Cells and Acellular Nerve Allografts Promotes Sciatic Nerve Regeneration and Repair through the JAK2/STAT3 Signaling Pathway in Rats.
Fu XM, Wang Y, Fu WL, Liu DH, Zhang CY, Wang QL, Tong XJ
Neuroscience 2019 Dec 1;422:134-145
Neuroscience 2019 Dec 1;422:134-145
Silencing TTK expression inhibits the proliferation and progression of prostate cancer.
Chen S, Wang J, Wang L, Peng H, Xiao L, Li C, Lin D, Yang K
Experimental cell research 2019 Dec 1;385(1):111669
Experimental cell research 2019 Dec 1;385(1):111669
The exocyst complex regulates insulin-stimulated glucose uptake of skeletal muscle cells.
Fujimoto BA, Young M, Carter L, Pang APS, Corley MJ, Fogelgren B, Polgar N
American journal of physiology. Endocrinology and metabolism 2019 Dec 1;317(6):E957-E972
American journal of physiology. Endocrinology and metabolism 2019 Dec 1;317(6):E957-E972
The focal adhesion scaffold protein Hic-5 regulates vimentin organization in fibroblasts.
Vohnoutka RB, Gulvady AC, Goreczny G, Alpha K, Handelman SK, Sexton JZ, Turner CE
Molecular biology of the cell 2019 Dec 1;30(25):3037-3056
Molecular biology of the cell 2019 Dec 1;30(25):3037-3056
Histone deacetylase 6 inhibitor ACY1215 offers a protective effect through the autophagy pathway in acute liver failure.
Chen Q, Wang Y, Jiao FZ, Shi CX, Gong ZJ
Life sciences 2019 Dec 1;238:116976
Life sciences 2019 Dec 1;238:116976
Paper/polymer composited microfluidic platform for screening cell viability and protein expression under a chemical gradient environment.
Lei KF, Goh A, Huang CH
Talanta 2019 Dec 1;205:120124
Talanta 2019 Dec 1;205:120124
Downregulation of TMPRSS4 Enhances Triple-Negative Breast Cancer Cell Radiosensitivity Through Cell Cycle and Cell Apoptosis Process Impairment.
Assani G, Segbo J, Yu X, Yessoufou A, Xiong Y, Zhou F, Zhou Y
Asian Pacific journal of cancer prevention : APJCP 2019 Dec 1;20(12):3679-3687
Asian Pacific journal of cancer prevention : APJCP 2019 Dec 1;20(12):3679-3687
Reduced m6A modification predicts malignant phenotypes and augmented Wnt/PI3K-Akt signaling in gastric cancer.
Zhang C, Zhang M, Ge S, Huang W, Lin X, Gao J, Gong J, Shen L
Cancer medicine 2019 Aug;8(10):4766-4781
Cancer medicine 2019 Aug;8(10):4766-4781
RECQL5 plays an essential role in maintaining genome stability and viability of triple-negative breast cancer cells.
Peng J, Tang L, Cai M, Chen H, Wong J, Zhang P
Cancer medicine 2019 Aug;8(10):4743-4752
Cancer medicine 2019 Aug;8(10):4743-4752
Dexmedetomidine alleviates LPS-induced apoptosis and inflammation in macrophages by eliminating damaged mitochondria via PINK1 mediated mitophagy.
Wang Y, Mao X, Chen H, Feng J, Yan M, Wang Y, Yu Y
International immunopharmacology 2019 Aug;73:471-481
International immunopharmacology 2019 Aug;73:471-481
Sulforaphane inhibits gastric cancer stem cells via suppressing sonic hedgehog pathway.
Ge M, Zhang L, Cao L, Xie C, Li X, Li Y, Meng Y, Chen Y, Wang X, Chen J, Zhang Q, Shao J, Zhong C
International journal of food sciences and nutrition 2019 Aug;70(5):570-578
International journal of food sciences and nutrition 2019 Aug;70(5):570-578
Angiogenic Factor AGGF1-Primed Endothelial Progenitor Cells Repair Vascular Defect in Diabetic Mice.
Yao Y, Li Y, Song Q, Hu C, Xie W, Xu C, Chen Q, Wang QK
Diabetes 2019 Aug;68(8):1635-1648
Diabetes 2019 Aug;68(8):1635-1648
Steroid-Enriched Fraction of Achyranthes bidentata Protects Amyloid β Peptide 1-40-Induced Cognitive Dysfunction and Neuroinflammation in Rats.
Lin LW, Tsai FH, Lan WC, Cheng YD, Lee SC, Wu CR
Molecular neurobiology 2019 Aug;56(8):5671-5688
Molecular neurobiology 2019 Aug;56(8):5671-5688
Pyrroline-5-Carboxylate Reductase 1 Accelerates the Migration and Invasion of Nonsmall Cell Lung Cancer In Vitro.
Sang S, Zhang C, Shan J
Cancer biotherapy & radiopharmaceuticals 2019 Aug;34(6):380-387
Cancer biotherapy & radiopharmaceuticals 2019 Aug;34(6):380-387
Total flavonoids from sea buckthorn ameliorates lipopolysaccharide/cigarette smoke-induced airway inflammation.
Ren QC, Li XH, Li QY, Yang HL, Wang HL, Zhang H, Zhao L, Jiang-Yong SL, Meng XL, Zhang Y, Shen XF
Phytotherapy research : PTR 2019 Aug;33(8):2102-2117
Phytotherapy research : PTR 2019 Aug;33(8):2102-2117
FAT1, a direct transcriptional target of E2F1, suppresses cell proliferation, migration and invasion in esophageal squamous cell carcinoma.
Wang Y, Wang G, Ma Y, Teng J, Wang Y, Cui Y, Dong Y, Shao S, Zhan Q, Liu X
Chinese journal of cancer research = Chung-kuo yen cheng yen chiu 2019 Aug;31(4):609-619
Chinese journal of cancer research = Chung-kuo yen cheng yen chiu 2019 Aug;31(4):609-619
Discovery of a Pathogenic Variant rs139379666 (p. P2974L) in ATM for Breast Cancer Risk in Chinese Populations.
Guo X, Lin W, Bai M, Li H, Wen W, Zeng C, Chen Z, He J, Chen J, Cai Q, Long J, Jia WH, Shu XO, Zheng W
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2019 Aug;28(8):1308-1315
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2019 Aug;28(8):1308-1315
Role of SNHG7-miR-653-5p-STAT2 feedback loop in regulating neuroblastoma progression.
Chi R, Chen X, Liu M, Zhang H, Li F, Fan X, Wang W, Lu H
Journal of cellular physiology 2019 Aug;234(8):13403-13412
Journal of cellular physiology 2019 Aug;234(8):13403-13412
Exosomes from tendon stem cells promote injury tendon healing through balancing synthesis and degradation of the tendon extracellular matrix.
Wang Y, He G, Guo Y, Tang H, Shi Y, Bian X, Zhu M, Kang X, Zhou M, Lyu J, Yang M, Mu M, Lai F, Lu K, Chen W, Zhou B, Zhang J, Tang K
Journal of cellular and molecular medicine 2019 Aug;23(8):5475-5485
Journal of cellular and molecular medicine 2019 Aug;23(8):5475-5485
MANF regulates splenic macrophage differentiation in mice.
Hou C, Wang D, Li X, He Y, Wei C, Jiang R, Liu J, Feng L, Shen Y
Immunology letters 2019 Aug;212:37-45
Immunology letters 2019 Aug;212:37-45
Migrasome formation is mediated by assembly of micron-scale tetraspanin macrodomains.
Huang Y, Zucker B, Zhang S, Elias S, Zhu Y, Chen H, Ding T, Li Y, Sun Y, Lou J, Kozlov MM, Yu L
Nature cell biology 2019 Aug;21(8):991-1002
Nature cell biology 2019 Aug;21(8):991-1002
Migrasomes provide regional cues for organ morphogenesis during zebrafish gastrulation.
Jiang D, Jiang Z, Lu D, Wang X, Liang H, Zhang J, Meng Y, Li Y, Wu D, Huang Y, Chen Y, Deng H, Wu Q, Xiong J, Meng A, Yu L
Nature cell biology 2019 Aug;21(8):966-977
Nature cell biology 2019 Aug;21(8):966-977
Identification of COMMD1 as a novel lamin A binding partner.
Jiang Z, Chen W, Zhou J, Peng Q, Zheng H, Yuan Y, Cui H, Zhao W, Sun X, Zhou Z, Liu X
Molecular medicine reports 2019 Aug;20(2):1790-1796
Molecular medicine reports 2019 Aug;20(2):1790-1796
E3 ligase Fbw7 participates in oxidative stress‑induced myocardial cell injury via interacting with Mcl‑1.
Li X, Zhang N, Zhang Y, Jia P, Guo Y, Tian Y, You S, Wu S, Sun Y
Molecular medicine reports 2019 Aug;20(2):1561-1568
Molecular medicine reports 2019 Aug;20(2):1561-1568
Roseburia intestinalis supernatant ameliorates colitis induced in mice by regulating the immune response.
Luo W, Shen Z, Deng M, Li X, Tan B, Xiao M, Wu S, Yang Z, Zhu C, Tian L, Wu X, Meng X, Quan Y, Wang X
Molecular medicine reports 2019 Aug;20(2):1007-1016
Molecular medicine reports 2019 Aug;20(2):1007-1016
Progranulin Promotes Bleomycin-Induced Skin Sclerosis by Enhancing Transforming Growth Factor-β/Smad3 Signaling through Up-Regulation of Transforming Growth Factor-β Type I Receptor.
Yang T, Zhang X, Chen A, Xiao Y, Sun S, Yan J, Cao Y, Chen J, Li F, Zhang Q, Huang K
The American journal of pathology 2019 Aug;189(8):1582-1593
The American journal of pathology 2019 Aug;189(8):1582-1593
Fibronectin regulates the self-renewal of rabbit limbal epithelial stem cells by stimulating the Wnt11/Fzd7/ROCK non-canonical Wnt pathway.
Zheng M, Tian C, Fan T, Xu B
Experimental eye research 2019 Aug;185:107681
Experimental eye research 2019 Aug;185:107681
MicroRNA-2053 overexpression inhibits the development and progression of hepatocellular carcinoma.
Song T, Ma K, Zhao C, Yang J, Liu J
Oncology letters 2019 Aug;18(2):2043-2049
Oncology letters 2019 Aug;18(2):2043-2049
Ursolic acid isolated from Isodon excisoides induces apoptosis and inhibits invasion of GBC-SD gallbladder carcinoma cells.
Chen H, Wu X, Duan Y, Zhi D, Zou M, Zhao Z, Zhang X, Yang X, Zhang J
Oncology letters 2019 Aug;18(2):1467-1474
Oncology letters 2019 Aug;18(2):1467-1474
Inducible LGALS3BP/90K activates antiviral innate immune responses by targeting TRAF6 and TRAF3 complex.
Xu G, Xia Z, Deng F, Liu L, Wang Q, Yu Y, Wang F, Zhu C, Liu W, Cheng Z, Zhu Y, Zhou L, Zhang Y, Lu M, Liu S
PLoS pathogens 2019 Aug;15(8):e1008002
PLoS pathogens 2019 Aug;15(8):e1008002
Sesterterpene MHO7 suppresses breast cancer cells as a novel estrogen receptor degrader.
Zhao Y, Zhao C, Lu J, Wu J, Li C, Hu Z, Tian W, Yang L, Xiang J, Zhou H, Deng Z, Huang J, Hong K
Pharmacological research 2019 Aug;146:104294
Pharmacological research 2019 Aug;146:104294
MicroRNA-128-3p aggravates doxorubicin-induced liver injury by promoting oxidative stress via targeting Sirtuin-1.
Zhao X, Jin Y, Li L, Xu L, Tang Z, Qi Y, Yin L, Peng J
Pharmacological research 2019 Aug;146:104276
Pharmacological research 2019 Aug;146:104276
Inhibitor of growth 4 (ING4) inhibits hypoxia-induced EMT by decreasing HIF-1α and snail in HK2 cells.
Lu L, Li J, Le Y, Jiang H
Acta histochemica 2019 Aug;121(6):695-703
Acta histochemica 2019 Aug;121(6):695-703
STAT3-induced long noncoding RNA LINC00668 promotes migration and invasion of non-small cell lung cancer via the miR-193a/KLF7 axis.
An YX, Shang YJ, Xu ZW, Zhang QC, Wang Z, Xuan WX, Zhang XJ
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Aug;116:109023
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Aug;116:109023
Ablation of core fucosylation attenuates the signal transduction via T cell receptor to suppress the T cell development.
Liang W, Mao S, Li M, Zhang N, Sun S, Fang H, Zhang J, Gu J, Wang J, Li W
Molecular immunology 2019 Aug;112:312-321
Molecular immunology 2019 Aug;112:312-321
Vasorin stimulates malignant progression and angiogenesis in glioma.
Liang W, Guo B, Ye J, Liu H, Deng W, Lin C, Zhong X, Wang L
Cancer science 2019 Aug;110(8):2558-2572
Cancer science 2019 Aug;110(8):2558-2572
CircAGFG1 sponges miR-203 to promote EMT and metastasis of non-small-cell lung cancer by upregulating ZNF281 expression.
Xue YB, Ding MQ, Xue L, Luo JH
Thoracic cancer 2019 Aug;10(8):1692-1701
Thoracic cancer 2019 Aug;10(8):1692-1701
Extracellular Vesicles from Albumin-Induced Tubular Epithelial Cells Promote the M1 Macrophage Phenotype by Targeting Klotho.
Jia Y, Zheng Z, Xue M, Zhang S, Hu F, Li Y, Yang Y, Zou M, Li S, Wang L, Guan M, Xue Y
Molecular therapy : the journal of the American Society of Gene Therapy 2019 Aug 7;27(8):1452-1466
Molecular therapy : the journal of the American Society of Gene Therapy 2019 Aug 7;27(8):1452-1466
LncRNA MEG3 acts a biomarker and regulates cell functions by targeting ADAR1 in colorectal cancer.
Wang W, Xie Y, Chen F, Liu X, Zhong LL, Wang HQ, Li QC
World journal of gastroenterology 2019 Aug 7;25(29):3972-3984
World journal of gastroenterology 2019 Aug 7;25(29):3972-3984
Berberine prevents stress-induced gut inflammation and visceral hypersensitivity and reduces intestinal motility in rats.
Yu ZC, Cen YX, Wu BH, Wei C, Xiong F, Li DF, Liu TT, Luo MH, Guo LL, Li YX, Wang LS, Wang JY, Yao J
World journal of gastroenterology 2019 Aug 7;25(29):3956-3971
World journal of gastroenterology 2019 Aug 7;25(29):3956-3971
Isoliquiritigenin Suppresses E2-Induced Uterine Leiomyoma Growth through the Modulation of Cell Death Program and the Repression of ECM Accumulation.
Lin PH, Kung HL, Chen HY, Huang KC, Hsia SM
Cancers 2019 Aug 7;11(8)
Cancers 2019 Aug 7;11(8)
A novel role for NFIA in restoring radiosensitivity in radioresistant NSCLC cells by downregulating the AKT and ERK pathways.
Sun C, Li Y, Tan Y, Zhang H, Liang Y, Zeng J, Yu J, Zou H
Biochemical and biophysical research communications 2019 Aug 6;515(4):558-564
Biochemical and biophysical research communications 2019 Aug 6;515(4):558-564
Mitochondrial NOS1 suppresses apoptosis in colon cancer cells through increasing SIRT3 activity.
Wang Q, Ye S, Chen X, Xu P, Li K, Zeng S, Huang M, Gao W, Chen J, Zhang Q, Zhong Z, Liu Q
Biochemical and biophysical research communications 2019 Aug 6;515(4):517-523
Biochemical and biophysical research communications 2019 Aug 6;515(4):517-523
TFEB-driven autophagy potentiates TGF-β induced migration in pancreatic cancer cells.
He R, Wang M, Zhao C, Shen M, Yu Y, He L, Zhao Y, Chen H, Shi X, Zhou M, Pan S, Liu Y, Guo X, Li X, Qin R
Journal of experimental & clinical cancer research : CR 2019 Aug 6;38(1):340
Journal of experimental & clinical cancer research : CR 2019 Aug 6;38(1):340
Generation of Human Fatty Livers Using Custom-Engineered Induced Pluripotent Stem Cells with Modifiable SIRT1 Metabolism.
Collin de l'Hortet A, Takeishi K, Guzman-Lepe J, Morita K, Achreja A, Popovic B, Wang Y, Handa K, Mittal A, Meurs N, Zhu Z, Weinberg F, Salomon M, Fox IJ, Deng CX, Nagrath D, Soto-Gutierrez A
Cell metabolism 2019 Aug 6;30(2):385-401.e9
Cell metabolism 2019 Aug 6;30(2):385-401.e9
Simvastatin inhibits the proliferation of HL-60 clone 15- derived eosinophils by inducing the arrest of the cell cycle in the G1/S phase.
Fu CH, Lee TJ, Huang CC, Chang PH, Tsai JW, Chuang LP, Su Pang JH
European journal of pharmacology 2019 Aug 5;856:172400
European journal of pharmacology 2019 Aug 5;856:172400
Endoplasmic reticulum stress and proteasome pathway involvement in human podocyte injury with a truncated COL4A3 mutation.
Zhang HD, Huang JN, Liu YZ, Ren H, Xie JY, Chen N
Chinese medical journal 2019 Aug 5;132(15):1823-1832
Chinese medical journal 2019 Aug 5;132(15):1823-1832
CBX8 promotes tumorigenesis and confers radioresistance in esophageal squamous cell carcinoma cells through targeting APAF1.
Zhang Y, Chen H, Zhu H, Sun X
Gene 2019 Aug 30;711:143949
Gene 2019 Aug 30;711:143949
Ibuprofen inhibited migration of skeletal muscle cells in association with downregulation of p130cas and CrkII expressions.
Liao CH, Lin LP, Yu TY, Hsu CC, Pang JS, Tsai WC
Skeletal muscle 2019 Aug 29;9(1):23
Skeletal muscle 2019 Aug 29;9(1):23
EXT1, Regulated by MiR-665, Promotes Cell Apoptosis via ERK1/2 Signaling Pathway in Acute Lymphoblastic Leukemia.
Liu NW, Huang X, Liu S, Lu Y
Medical science monitor : international medical journal of experimental and clinical research 2019 Aug 29;25:6491-6503
Medical science monitor : international medical journal of experimental and clinical research 2019 Aug 29;25:6491-6503
Identification of Glyceraldehyde-3-Phosphate Dehydrogenase Gene as an Alternative Safe Harbor Locus in Pig Genome.
Han X, Xiong Y, Zhao C, Xie S, Li C, Li X, Liu X, Li K, Zhao S, Ruan J
Genes 2019 Aug 29;10(9)
Genes 2019 Aug 29;10(9)
SIV-Mediated Synaptic Dysfunction Is Associated with an Increase in Synapsin Site 1 Phosphorylation and Impaired PP2A Activity.
Shekarabi M, Robinson JA, Smith MD, Burdo TH
The Journal of neuroscience : the official journal of the Society for Neuroscience 2019 Aug 28;39(35):7006-7018
The Journal of neuroscience : the official journal of the Society for Neuroscience 2019 Aug 28;39(35):7006-7018
Nelfinavir and lenalidomide/dexamethasone in patients with lenalidomide-refractory multiple myeloma. A phase I/II Trial (SAKK 39/10).
Hitz F, Kraus M, Pabst T, Hess D, Besse L, Silzle T, Novak U, Seipel K, Rondeau S, Stüdeli S, Vilei SB, Samaras P, Mey U, Driessen C, Swiss Group for Clinical Cancer Research SAKK.
Blood cancer journal 2019 Aug 27;9(9):70
Blood cancer journal 2019 Aug 27;9(9):70
Anti-high mobility group box-1 antibody attenuated vascular smooth muscle cell phenotypic switching and vascular remodelling after subarachnoid haemorrhage in rats.
Wang L, Zhang Z, Liang L, Wu Y, Zhong J, Sun X
Neuroscience letters 2019 Aug 24;708:134338
Neuroscience letters 2019 Aug 24;708:134338
Topoisomerase inhibitors promote cancer cell motility via ROS-mediated activation of JAK2-STAT1-CXCL1 pathway.
Liu J, Qu L, Meng L, Shou C
Journal of experimental & clinical cancer research : CR 2019 Aug 22;38(1):370
Journal of experimental & clinical cancer research : CR 2019 Aug 22;38(1):370
CircRNA CBL.11 suppresses cell proliferation by sponging miR-6778-5p in colorectal cancer.
Li H, Jin X, Liu B, Zhang P, Chen W, Li Q
BMC cancer 2019 Aug 22;19(1):826
BMC cancer 2019 Aug 22;19(1):826
Depletion of phosphatidylinositol 4-phosphate at the Golgi translocates K-Ras to mitochondria.
Miller TE, Henkels KM, Huddleston M, Salisbury R, Hussain SM, Sasaki AT, Cho KJ
Journal of cell science 2019 Aug 22;132(16)
Journal of cell science 2019 Aug 22;132(16)
MiR-1197-3p regulates testosterone secretion in goat Leydig cells via targeting PPARGC1A.
An SY, Zhang GM, Liu ZF, Zhou C, Yang PC, Wang F
Gene 2019 Aug 20;710:131-139
Gene 2019 Aug 20;710:131-139
CBX3/HP1γ promotes tumor proliferation and predicts poor survival in hepatocellular carcinoma.
Zhong X, Kan A, Zhang W, Zhou J, Zhang H, Chen J, Tang S
Aging 2019 Aug 2;11(15):5483-5497
Aging 2019 Aug 2;11(15):5483-5497
Internalization Characterization of Si Nanorod with Camouflaged Cell Membrane Proteins Reveals ATXN2 as a Negative Regulator.
Lu Y, Dai J, Kong N, Liu J, Gong J, Yao Y
Cells 2019 Aug 19;8(8)
Cells 2019 Aug 19;8(8)
Combined Assembly and Targeted Integration of Multigene for Nitrogenase Biosynthetic Pathway in Saccharomyces cerevisiae.
Liu X, Wang M, Song Y, Li Y, Liu P, Shi H, Li Y, Hao T, Zhang H, Jiang W, Chen S, Li J
ACS synthetic biology 2019 Aug 16;8(8):1766-1775
ACS synthetic biology 2019 Aug 16;8(8):1766-1775
CRABP2 regulates invasion and metastasis of breast cancer through hippo pathway dependent on ER status.
Feng X, Zhang M, Wang B, Zhou C, Mu Y, Li J, Liu X, Wang Y, Song Z, Liu P
Journal of experimental & clinical cancer research : CR 2019 Aug 16;38(1):361
Journal of experimental & clinical cancer research : CR 2019 Aug 16;38(1):361
miR-504 suppresses mesenchymal phenotype of glioblastoma by directly targeting the FZD7-mediated Wnt-β-catenin pathway.
Liu Q, Guan Y, Li Z, Wang Y, Liu Y, Cui R, Wang Y
Journal of experimental & clinical cancer research : CR 2019 Aug 16;38(1):358
Journal of experimental & clinical cancer research : CR 2019 Aug 16;38(1):358
IMM-H007 improves heart function via reducing cardiac fibrosis.
Ge W, Zhang W, Gao R, Li B, Zhu H, Wang J
European journal of pharmacology 2019 Aug 15;857:172442
European journal of pharmacology 2019 Aug 15;857:172442
The combination of lonafarnib and sorafenib induces cyclin D1 degradation via ATG3-mediated autophagic flux in hepatocellular carcinoma cells.
Wang J, Wei H, Huang Y, Chen D, Zeng G, Lian Y, Huang Y
Aging 2019 Aug 13;11(15):5769-5785
Aging 2019 Aug 13;11(15):5769-5785
Induction of Fibroblast Senescence During Mouse Corneal Wound Healing.
Wang X, Qu M, Li J, Danielson P, Yang L, Zhou Q
Investigative ophthalmology & visual science 2019 Aug 1;60(10):3669-3679
Investigative ophthalmology & visual science 2019 Aug 1;60(10):3669-3679
Corneal Denervation Causes Epithelial Apoptosis Through Inhibiting NAD+ Biosynthesis.
Li Y, Ma X, Li J, Yang L, Zhao X, Qi X, Zhang X, Zhou Q, Shi W
Investigative ophthalmology & visual science 2019 Aug 1;60(10):3538-3546
Investigative ophthalmology & visual science 2019 Aug 1;60(10):3538-3546
p21-Activated kinase 3 promotes cancer stem cell phenotypes through activating the Akt-GSK3β-β-catenin signaling pathway in pancreatic cancer cells.
Wu HY, Yang MC, Ding LY, Chen CS, Chu PC
Cancer letters 2019 Aug 1;456:13-22
Cancer letters 2019 Aug 1;456:13-22
Retinol binding protein 4 mediates MEHP-induced glucometabolic abnormalities in HepG2 cells.
Wang F, Chang C, Li R, Zhang Z, Jiang H, Zeng N, Li D, Chen L, Xiao Y, Chen W, Wang Q
Toxicology 2019 Aug 1;424:152236
Toxicology 2019 Aug 1;424:152236
RUNX1 promotes tumour metastasis by activating the Wnt/β-catenin signalling pathway and EMT in colorectal cancer.
Li Q, Lai Q, He C, Fang Y, Yan Q, Zhang Y, Wang X, Gu C, Wang Y, Ye L, Han L, Lin X, Chen J, Cai J, Li A, Liu S
Journal of experimental & clinical cancer research : CR 2019 Aug 1;38(1):334
Journal of experimental & clinical cancer research : CR 2019 Aug 1;38(1):334
Roseburia intestinalis inhibits oncostatin M and maintains tight junction integrity in a murine model of acute experimental colitis.
Tan B, Luo W, Shen Z, Xiao M, Wu S, Meng X, Wu X, Yang Z, Tian L, Wang X
Scandinavian journal of gastroenterology 2019 Apr;54(4):432-440
Scandinavian journal of gastroenterology 2019 Apr;54(4):432-440
Adaptive EGF expression sensitizes pancreatic cancer cells to ionizing radiation through activation of the cyclin D1/P53/PARP pathway.
Liu X, Chen H, Hou Y, Ma X, Ye M, Huang R, Hu B, Cao H, Xu L, Liu M, Li L, Gao J, Bai Y
International journal of oncology 2019 Apr;54(4):1466-1480
International journal of oncology 2019 Apr;54(4):1466-1480
Expression patterns of C1ql4 and its cell-adhesion GPCR Bai3 in the murine testis and functional roles in steroidogenesis.
Tan A, Ke S, Chen Y, Chen L, Lu X, Ding F, Yang L, Tang Y, Yu Y
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 Apr;33(4):4893-4906
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 Apr;33(4):4893-4906
Treatment with metformin prevents myocardial ischemia-reperfusion injury via STEAP4 signaling pathway.
Luo T, Zeng X, Yang W, Zhang Y
Anatolian journal of cardiology 2019 Apr;21(5):261-271
Anatolian journal of cardiology 2019 Apr;21(5):261-271
Comparative localization of cystathionine beta synthases and cystathionine gamma lyase in canine, non-human primate and human retina.
Badiei A, Sudharsan R, Santana E, Dunaief JL, Aguirre GD
Experimental eye research 2019 Apr;181:72-84
Experimental eye research 2019 Apr;181:72-84
Type III interferon-induced CBFβ inhibits HBV replication by hijacking HBx.
Xu F, Song H, Xiao Q, Li N, Zhang H, Cheng G, Tan G
Cellular & molecular immunology 2019 Apr;16(4):357-366
Cellular & molecular immunology 2019 Apr;16(4):357-366
5-(3,4-Difluorophenyl)-3-(6-methylpyridin-3-yl)-1,2,4-oxadiazole (DDO-7263), a novel Nrf2 activator targeting brain tissue, protects against MPTP-induced subacute Parkinson's disease in mice by inhibiting the NLRP3 inflammasome and protects PC12 cells against oxidative stress.
Xu LL, Wu YF, Yan F, Li CC, Dai Z, You QD, Jiang ZY, Di B
Free radical biology & medicine 2019 Apr;134:288-303
Free radical biology & medicine 2019 Apr;134:288-303
Role of p53 mediated miR-23a/CXCL12 pathway in osteogenic differentiation of bone mesenchymal stem cells on nanostructured titanium surfaces.
Zhuang XM, Zhou B, Yuan KF
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Apr;112:108649
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Apr;112:108649
Ribociclib, a selective cyclin D kinase 4/6 inhibitor, inhibits proliferation and induces apoptosis of human cervical cancer in vitro and in vivo.
Xiong Y, Li T, Assani G, Ling H, Zhou Q, Zeng Y, Zhou F, Zhou Y
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Apr;112:108602
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Apr;112:108602
Adjudin synergizes with paclitaxel and inhibits cell growth and metastasis by regulating the sirtuin 3-Forkhead box O3a axis in human small-cell lung cancer.
Wang X, Zeng Q, Li Z, Yang X, Xia W, Chen Z
Thoracic cancer 2019 Apr;10(4):642-658
Thoracic cancer 2019 Apr;10(4):642-658
Oxytocin Receptor Antagonists, Atosiban and Nolasiban, Inhibit Prostaglandin F2α-induced Contractions and Inflammatory Responses in Human Myometrium.
Kim SH, Riaposova L, Ahmed H, Pohl O, Chollet A, Gotteland JP, Hanyaloglu A, Bennett PR, Terzidou V
Scientific reports 2019 Apr 8;9(1):5792
Scientific reports 2019 Apr 8;9(1):5792
GTSE1 is involved in breast cancer progression in p53 mutation-dependent manner.
Lin F, Xie YJ, Zhang XK, Huang TJ, Xu HF, Mei Y, Liang H, Hu H, Lin ST, Luo FF, Lang YH, Peng LX, Qian CN, Huang BJ
Journal of experimental & clinical cancer research : CR 2019 Apr 8;38(1):152
Journal of experimental & clinical cancer research : CR 2019 Apr 8;38(1):152
HAMP Downregulation Contributes to Aggressive Hepatocellular Carcinoma via Mechanism Mediated by Cyclin4-Dependent Kinase-1/STAT3 Pathway.
Shen Y, Li X, Su Y, Badshah SA, Zhang B, Xue Y, Shang P
Diagnostics (Basel, Switzerland) 2019 Apr 30;9(2)
Diagnostics (Basel, Switzerland) 2019 Apr 30;9(2)
TMEM30A deficiency in endothelial cells impairs cell proliferation and angiogenesis.
Zhang S, Liu W, Yang Y, Sun K, Li S, Xu H, Yang M, Zhang L, Zhu X
Journal of cell science 2019 Apr 3;132(7)
Journal of cell science 2019 Apr 3;132(7)
FOXO1-regulated lncRNA LINC01197 inhibits pancreatic adenocarcinoma cell proliferation by restraining Wnt/β-catenin signaling.
Ling J, Wang F, Liu C, Dong X, Xue Y, Jia X, Song W, Li Q
Journal of experimental & clinical cancer research : CR 2019 Apr 26;38(1):179
Journal of experimental & clinical cancer research : CR 2019 Apr 26;38(1):179
Numb inhibits epithelial-mesenchymal transition via RBP-Jκ-dependent Notch1/PTEN/FAK signaling pathway in tongue cancer.
Li JY, Huang WX, Zhou X, Chen J, Li Z
BMC cancer 2019 Apr 25;19(1):391
BMC cancer 2019 Apr 25;19(1):391
YAP Aggravates Inflammatory Bowel Disease by Regulating M1/M2 Macrophage Polarization and Gut Microbial Homeostasis.
Zhou X, Li W, Wang S, Zhang P, Wang Q, Xiao J, Zhang C, Zheng X, Xu X, Xue S, Hui L, Ji H, Wei B, Wang H
Cell reports 2019 Apr 23;27(4):1176-1189.e5
Cell reports 2019 Apr 23;27(4):1176-1189.e5
Crosstalk Between Connexin32 and Mitochondrial Apoptotic Signaling Pathway Plays a Pivotal Role in Renal Ischemia Reperfusion-Induced Acute Kidney Injury.
Chen C, Yao W, Wu S, Zhou S, Ge M, Gu Y, Li X, Chen G, Bellanti JA, Zheng SG, Yuan D, Hei Z
Antioxidants & redox signaling 2019 Apr 20;30(12):1521-1538
Antioxidants & redox signaling 2019 Apr 20;30(12):1521-1538
Stabilized Peptide HDAC Inhibitors Derived from HDAC1 Substrate H3K56 for the Treatment of Cancer Stem-Like Cells In Vivo.
Wang D, Li W, Zhao R, Chen L, Liu N, Tian Y, Zhao H, Xie M, Lu F, Fang Q, Liang W, Yin F, Li Z
Cancer research 2019 Apr 15;79(8):1769-1783
Cancer research 2019 Apr 15;79(8):1769-1783
Benzoxazine monomer derived carbon dots as a broad-spectrum agent to block viral infectivity.
Huang S, Gu J, Ye J, Fang B, Wan S, Wang C, Ashraf U, Li Q, Wang X, Shao L, Song Y, Zheng X, Cao F, Cao S
Journal of colloid and interface science 2019 Apr 15;542:198-206
Journal of colloid and interface science 2019 Apr 15;542:198-206
Proteomic analysis of mouse ovaries during the prepubertal stages.
Xiong J, Wu M, Zhang Q, Zhang C, Xiong G, Ma L, Lu Z, Wang S
Experimental cell research 2019 Apr 15;377(1-2):36-46
Experimental cell research 2019 Apr 15;377(1-2):36-46
Activation of GPR40 produces mechanical antiallodynia via the spinal glial interleukin-10/β-endorphin pathway.
Mao XF, Wu HY, Tang XQ, Ali U, Liu H, Wang YX
Journal of neuroinflammation 2019 Apr 13;16(1):84
Journal of neuroinflammation 2019 Apr 13;16(1):84
CDK4/6 inhibitor palbociclib enhances the effect of pyrotinib in HER2-positive breast cancer.
Zhang K, Hong R, Kaping L, Xu F, Xia W, Qin G, Zheng Q, Lu Q, Zhai Q, Shi Y, Yuan Z, Deng W, Chen M, Wang S
Cancer letters 2019 Apr 10;447:130-140
Cancer letters 2019 Apr 10;447:130-140
Mild thermotherapy and hyperbaric oxygen enhance sensitivity of TMZ/PSi nanoparticles via decreasing the stemness in glioma.
Zeng X, Wang Q, Tan X, Jia L, Li Y, Hu M, Zhang Z, Bai X, Zhu Y, Yang X
Journal of nanobiotechnology 2019 Apr 1;17(1):47
Journal of nanobiotechnology 2019 Apr 1;17(1):47
Exosomal ephrinA2 derived from serum as a potential biomarker for prostate cancer.
Li S, Zhao Y, Chen W, Yin L, Zhu J, Zhang H, Cai C, Li P, Huang L, Ma P
Journal of Cancer 2018;9(15):2659-2665
Journal of Cancer 2018;9(15):2659-2665
P21-activated kinase 7 (PAK7) interacts with and activates Wnt/β-catenin signaling pathway in breast cancer.
Li K, Xu X, He Y, Tian Y, Pan W, Xu L, Ma Y, Gao Y, Gao J, Qi Y, Wei L, Zhang J
Journal of Cancer 2018;9(10):1821-1835
Journal of Cancer 2018;9(10):1821-1835
TANK-Binding Kinase 1 (TBK1) Isoforms Negatively Regulate Type I Interferon Induction by Inhibiting TBK1-IRF3 Interaction and IRF3 Phosphorylation.
Hu YW, Zhang J, Wu XM, Cao L, Nie P, Chang MX
Frontiers in immunology 2018;9:84
Frontiers in immunology 2018;9:84
Core Fucosylation of the T Cell Receptor Is Required for T Cell Activation.
Liang W, Mao S, Sun S, Li M, Li Z, Yu R, Ma T, Gu J, Zhang J, Taniguchi N, Li W
Frontiers in immunology 2018;9:78
Frontiers in immunology 2018;9:78
Fertility Enhancement but Premature Ovarian Failure in esr1-Deficient Female Zebrafish.
Chen Y, Tang H, Wang L, He J, Guo Y, Liu Y, Liu X, Lin H
Frontiers in endocrinology 2018;9:567
Frontiers in endocrinology 2018;9:567
Bioinformatics Analysis Identifies p53 as a Candidate Prognostic Biomarker for Neuropathic Pain.
Gao Y, Sun N, Wang L, Wu Y, Ma L, Hong J, Ren J, Zhu B, Yu L, Yan M
Frontiers in genetics 2018;9:320
Frontiers in genetics 2018;9:320
The Host Restriction Factor Interferon-Inducible Transmembrane Protein 3 Inhibits Vaccinia Virus Infection.
Li C, Du S, Tian M, Wang Y, Bai J, Tan P, Liu W, Yin R, Wang M, Jiang Y, Li Y, Zhu N, Zhu Y, Li T, Wu S, Jin N, He F
Frontiers in immunology 2018;9:228
Frontiers in immunology 2018;9:228
Tc17/IL-17A Up-Regulated the Expression of MMP-9 via NF-κB Pathway in Nasal Epithelial Cells of Patients With Chronic Rhinosinusitis.
Chen X, Chang L, Li X, Huang J, Yang L, Lai X, Huang Z, Wang Z, Wu X, Zhao J, Bellanti JA, Zheng SG, Zhang G
Frontiers in immunology 2018;9:2121
Frontiers in immunology 2018;9:2121
Sesamin Protects the Femoral Head From Osteonecrosis by Inhibiting ROS-Induced Osteoblast Apoptosis in Rat Model.
Deng S, Zhou JL, Fang HS, Nie ZG, Chen S, Peng H
Frontiers in physiology 2018;9:1787
Frontiers in physiology 2018;9:1787
Lactobacillus rhamnosus GR-1 Ameliorates Escherichia coli-Induced Activation of NLRP3 and NLRC4 Inflammasomes With Differential Requirement for ASC.
Wu Q, Zhu YH, Xu J, Liu X, Duan C, Wang MJ, Wang JF
Frontiers in microbiology 2018;9:1661
Frontiers in microbiology 2018;9:1661
Effective Amelioration of Liver Fibrosis Through Lentiviral Vector Carrying Toxoplasma gondii gra15II in Murine Model.
Liu L, Jin M, Tao Q, Yu L, Du J, Wang C, Luo Q, Xing T, Xu Y, Shen J, Chu D
Frontiers in immunology 2018;9:1572
Frontiers in immunology 2018;9:1572
MicroRNA-181a Functions as an Oncogene in Gastric Cancer by Targeting Caprin-1.
Lu Q, Chen Y, Sun D, Wang S, Ding K, Liu M, Zhang Y, Miao Y, Liu H, Zhou F
Frontiers in pharmacology 2018;9:1565
Frontiers in pharmacology 2018;9:1565
DEAD-Box Helicase 5 Interacts With Transcription Factor 12 and Promotes the Progression of Osteosarcoma by Stimulating Cell Cycle Progression.
Chen Y, Wang Q, Wang Q, Liu J, Jiang X, Zhang Y, Liu Y, Zhou F, Liu H
Frontiers in pharmacology 2018;9:1558
Frontiers in pharmacology 2018;9:1558
Coagulation Factor X Regulated by CASC2c Recruited Macrophages and Induced M2 Polarization in Glioblastoma Multiforme.
Zhang Y, Feng J, Fu H, Liu C, Yu Z, Sun Y, She X, Li P, Zhao C, Liu Y, Liu T, Liu Q, Liu Q, Li G, Wu M
Frontiers in immunology 2018;9:1557
Frontiers in immunology 2018;9:1557
Latent Membrane Protein 1 of Epstein-Barr Virus Promotes RIG-I Degradation Mediated by Proteasome Pathway.
Xu C, Sun L, Liu W, Duan Z
Frontiers in immunology 2018;9:1446
Frontiers in immunology 2018;9:1446
Invalidation of Microsomal Prostaglandin E Synthase-1 (mPGES-1) Reduces Diet-Induced Low-Grade Inflammation and Adiposity.
Pierre C, Guillebaud F, Airault C, Baril N, Barbouche R, Save E, Gaigé S, Bariohay B, Dallaporta M, Troadec JD
Frontiers in physiology 2018;9:1358
Frontiers in physiology 2018;9:1358
Non-Hematopoietic MLKL Protects Against Salmonella Mucosal Infection by Enhancing Inflammasome Activation.
Yu SX, Chen W, Liu ZZ, Zhou FH, Yan SQ, Hu GQ, Qin XX, Zhang J, Ma K, Du CT, Gu JM, Deng XM, Han WY, Yang YJ
Frontiers in immunology 2018;9:119
Frontiers in immunology 2018;9:119
Evaluation of Oral Antiretroviral Drugs in Mice With Metabolic and Neurologic Complications.
Tsai FJ, Ho MW, Lai CH, Chou CH, Li JP, Cheng CF, Wu YC, Liu X, Tsang H, Lin TH, Liao CC, Huang SM, Lin JC, Lin CC, Hsieh CL, Liang WM, Lin YJ
Frontiers in pharmacology 2018;9:1004
Frontiers in pharmacology 2018;9:1004
Efficient delivery of nucleic acid molecules into skin by combined use of microneedle roller and flexible interdigitated electroporation array.
Huang D, Zhao D, Wang X, Li C, Yang T, Du L, Wei Z, Cheng Q, Cao H, Liang Z, Huang Y, Li Z
Theranostics 2018;8(9):2361-2376
Theranostics 2018;8(9):2361-2376
OVOL2 links stemness and metastasis via fine-tuning epithelial-mesenchymal transition in nasopharyngeal carcinoma.
Qi XK, Han HQ, Zhang HJ, Xu M, Li L, Chen L, Xiang T, Feng QS, Kang T, Qian CN, Cai MY, Tao Q, Zeng YX, Feng L
Theranostics 2018;8(8):2202-2216
Theranostics 2018;8(8):2202-2216
S6K1 phosphorylation-dependent degradation of Mxi1 by β-Trcp ubiquitin ligase promotes Myc activation and radioresistance in lung cancer.
Huang Y, Hu K, Zhang S, Dong X, Yin Z, Meng R, Zhao Y, Dai X, Zhang T, Yang K, Liu L, Huang K, Shi S, Zhang Y, Chen J, Wu G, Xu S
Theranostics 2018;8(5):1286-1300
Theranostics 2018;8(5):1286-1300
Long noncoding RNA CCAT2 is activated by E2F1 and exerts oncogenic properties by interacting with PTTG1 in pituitary adenomas.
Fu D, Zhang Y, Cui H
American journal of cancer research 2018;8(2):245-255
American journal of cancer research 2018;8(2):245-255
Dengue Virus Infects Primary Human Hair Follicle Dermal Papilla Cells.
Wei KC, Huang MS, Chang TH
Frontiers in cellular and infection microbiology 2018;8:268
Frontiers in cellular and infection microbiology 2018;8:268
Neurodegeneration-associated FUS is a novel regulator of circadian gene expression.
Jiang X, Zhang T, Wang H, Wang T, Qin M, Bao P, Wang R, Liu Y, Chang HC, Yan J, Xu J
Translational neurodegeneration 2018;7:24
Translational neurodegeneration 2018;7:24
Does the Genetic Feature of the Chinese Tree Shrew (Tupaia belangeri chinensis) Support Its Potential as a Viable Model for Alzheimer's Disease Research?
Fan Y, Luo R, Su LY, Xiang Q, Yu D, Xu L, Chen JQ, Bi R, Wu DD, Zheng P, Yao YG
Journal of Alzheimer's disease : JAD 2018;61(3):1015-1028
Journal of Alzheimer's disease : JAD 2018;61(3):1015-1028
Huperzine A attenuates nonalcoholic fatty liver disease by regulating hepatocyte senescence and apoptosis: an in vitro study.
Hu XN, Wang JF, Huang YQ, Wang Z, Dong FY, Ma HF, Bao ZJ
PeerJ 2018;6:e5145
PeerJ 2018;6:e5145
miRNA-1290 Promotes Aggressiveness in Pancreatic Ductal Adenocarcinoma by Targeting IKK1.
Ta N, Huang X, Zheng K, Zhang Y, Gao Y, Deng L, Zhang B, Jiang H, Zheng J
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;51(2):711-728
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;51(2):711-728
FGFR2 Promotes Gastric Cancer Progression by Inhibiting the Expression of Thrombospondin4 via PI3K-Akt-Mtor Pathway.
Huang T, Liu D, Wang Y, Li P, Sun L, Xiong H, Dai Y, Zou M, Yuan X, Qiu H
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;50(4):1332-1345
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;50(4):1332-1345
Activator Protein-2β Promotes Tumor Growth and Predicts Poor Prognosis in Breast Cancer.
Li Z, Xu X, Luo M, Hao J, Zhao S, Yu W, Xiao X, Wu J, Zheng F, Chen M, Li Y, Qin G, Liao Y, Zhao X, Yu X, Guo W, Zou L, Deng W
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;47(5):1925-1935
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;47(5):1925-1935
HSP70/HSP90-Organizing Protein Contributes to Gastric Cancer Progression in an Autocrine Fashion and Predicts Poor Survival in Gastric Cancer.
Zhai E, Liang W, Lin Y, Huang L, He X, Cai S, Chen J, Zhang N, Li J, Zhang Q, He Y, Zeng Z, Chen M, Xu L, Peng S
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;47(2):879-892
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;47(2):879-892
Asiatic Acid (AA) Sensitizes Multidrug-Resistant Human Lung Adenocarcinoma A549/DDP Cells to Cisplatin (DDP) via Downregulation of P-Glycoprotein (MDR1) and Its Targets.
Cheng Q, Liao M, Hu H, Li H, Wu L
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;47(1):279-292
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;47(1):279-292
17β-Estradiol inhibits intervertebral disc degeneration by down-regulating MMP-3 and MMP-13 and up-regulating type II collagen in a rat model.
Liu S, Yang SD, Huo XW, Yang DL, Ma L, Ding WY
Artificial cells, nanomedicine, and biotechnology 2018;46(sup2):182-191
Artificial cells, nanomedicine, and biotechnology 2018;46(sup2):182-191
Neuroprotective Effects of Magnesium Lithospermate B against Subarachnoid Hemorrhage in Rats.
Peng Y, He P, Fan L, Xu H, Li J, Chen T, Ruan W, Dou Z, Chen G
The American journal of Chinese medicine 2018;46(6):1225-1241
The American journal of Chinese medicine 2018;46(6):1225-1241
NR4A1 is Involved in Fibrogenesis in Ovarian Endometriosis.
Zeng X, Yue Z, Gao Y, Jiang G, Zeng F, Shao Y, Huang J, Yin M, Li Y
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;46(3):1078-1090
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;46(3):1078-1090
Ethyl Pyruvate Attenuates CaCl2-Induced Tubular Epithelial Cell Injury by Inhibiting Autophagy and Inflammatory Responses.
Zhao J, Cheng J, Li C, Xu M, Ma C, Qin L, Yi K, Liao N
Kidney & blood pressure research 2018;43(5):1585-1595
Kidney & blood pressure research 2018;43(5):1585-1595
Inhibition of Autophagy Attenuated Ethylene Glycol Induced Crystals Deposition and Renal Injury in a Rat Model of Nephrolithiasis.
Liu Y, Liu Q, Wang X, He Z, Li D, Guan X, Tao Z, Deng Y
Kidney & blood pressure research 2018;43(1):246-255
Kidney & blood pressure research 2018;43(1):246-255
Renal sympathetic denervation lowers arterial pressure in canines with obesity-induced hypertension by regulating GAD65 and AT1R expression in rostral ventrolateral medulla.
Shen Z, Weng C, Zhang Z, Wang X, Yang K
Clinical and experimental hypertension (New York, N.Y. : 1993) 2018;40(1):49-57
Clinical and experimental hypertension (New York, N.Y. : 1993) 2018;40(1):49-57
MST1 Suppression Reduces Early Brain Injury by Inhibiting the NF-κB/MMP-9 Pathway after Subarachnoid Hemorrhage in Mice.
Qu J, Zhao H, Li Q, Pan P, Ma K, Liu X, Feng H, Chen Y
Behavioural neurology 2018;2018:6470957
Behavioural neurology 2018;2018:6470957
Hypoxia Enhances Fusion of Oral Squamous Carcinoma Cells and Epithelial Cells Partly via the Epithelial-Mesenchymal Transition of Epithelial Cells.
Huang CM, Yan TL, Xu Z, Wang M, Zhou XC, Jiang EH, Liu K, Shao Z, Shang ZJ
BioMed research international 2018;2018:5015203
BioMed research international 2018;2018:5015203
Increased Autophagy Enhances the Resistance to Tumor Necrosis Factor-Alpha Treatment in Rheumatoid Arthritis Human Fibroblast-Like Synovial Cell.
Dai Y, Ding J, Yin W, He Y, Yu F, Ye C, Hu S, Yu Y
BioMed research international 2018;2018:4941027
BioMed research international 2018;2018:4941027
Hydrogen Sulfide Alleviates Acute Myocardial Ischemia Injury by Modulating Autophagy and Inflammation Response under Oxidative Stress.
Bai YD, Yang YR, Mu XP, Lin G, Wang YP, Jin S, Chen Y, Wang MJ, Zhu YC
Oxidative medicine and cellular longevity 2018;2018:3402809
Oxidative medicine and cellular longevity 2018;2018:3402809
3-(1H-Benzo[d]imidazol-6-yl)-5-(4-fluorophenyl)-1,2,4-oxadiazole (DDO7232), a Novel Potent Nrf2/ARE Inducer, Ameliorates DSS-Induced Murine Colitis and Protects NCM460 Cells against Oxidative Stress via ERK1/2 Phosphorylation.
Xu LL, Liu T, Wang L, Li L, Wu YF, Li CC, Di B, You QD, Jiang ZY
Oxidative medicine and cellular longevity 2018;2018:3271617
Oxidative medicine and cellular longevity 2018;2018:3271617
High Expression of ITGA3 Promotes Proliferation and Cell Cycle Progression and Indicates Poor Prognosis in Intrahepatic Cholangiocarcinoma.
Huang Y, Kong Y, Zhang L, He T, Zhou X, Yan Y, Zhang L, Zhou D, Lu S, Zhou J, Zhou L, Xie H, Zheng S, Wang W
BioMed research international 2018;2018:2352139
BioMed research international 2018;2018:2352139
Selenoprotein S Attenuates Tumor Necrosis Factor-α-Induced Dysfunction in Endothelial Cells.
Cui S, Men L, Li Y, Zhong Y, Yu S, Li F, Du J
Mediators of inflammation 2018;2018:1625414
Mediators of inflammation 2018;2018:1625414
RNF138 confers cisplatin resistance in gastric cancer cells via activating Chk1 signaling pathway.
Lu Y, Han D, Liu W, Huang R, Ou J, Chen X, Zhang X, Wang X, Li S, Wang L, Liu C, Miao S, Wang L, Ma C, Song W
Cancer biology & therapy 2018;19(12):1128-1138
Cancer biology & therapy 2018;19(12):1128-1138
MicroRNA-133b/EGFR axis regulates esophageal squamous cell carcinoma metastases by suppressing anoikis resistance and anchorage-independent growth.
Zhu JF, Liu Y, Huang H, Shan L, Han ZG, Liu JY, Li YL, Dong X, Zeng W
Cancer cell international 2018;18:193
Cancer cell international 2018;18:193
Paraoxonase 3 is involved in the multi-drug resistance of esophageal cancer.
Huang D, Wang Y, He Y, Wang G, Wang W, Han X, Sun Y, Lin L, Shan B, Shen G, Cheng M, Bian G, Fang X, Hu S, Pan Y
Cancer cell international 2018;18:168
Cancer cell international 2018;18:168
The lncRNA CCAT1 upregulates TGFβR1 via sponging miR-490-3p to promote TGFβ1-induced EMT of ovarian cancer cells.
Mu Y, Li N, Cui YL
Cancer cell international 2018;18:145
Cancer cell international 2018;18:145
Downregulation of MiR-203a Disinhibits Bmi1 and Promotes Growth and Proliferation of Keratinocytes in Cholesteatoma.
Zang J, Hui L, Yang N, Yang B, Jiang X
International journal of medical sciences 2018;15(5):447-455
International journal of medical sciences 2018;15(5):447-455
Amelioration of hepatic steatosis is associated with modulation of gut microbiota and suppression of hepatic miR-34a in Gynostemma pentaphylla (Thunb.) Makino treated mice.
Jia N, Lin X, Ma S, Ge S, Mu S, Yang C, Shi S, Gao L, Xu J, Bo T, Zhao J
Nutrition & metabolism 2018;15:86
Nutrition & metabolism 2018;15:86
Overexpression of Toll-like Receptor 4-linked Mitogen-activated Protein Kinase Signaling Contributes to Internalization of Escherichia coli in Sheep.
Wang S, Cao Y, Deng S, Jiang X, Wang J, Zhang X, Zhang J, Liu G, Lian Z
International journal of biological sciences 2018;14(9):1022-1032
International journal of biological sciences 2018;14(9):1022-1032
PARI functions as a new transcriptional target of FOXM1 involved in gastric cancer development.
Zhang Y, Ye X, Chen L, Wu Q, Gao Y, Li Y
International journal of biological sciences 2018;14(5):531-541
International journal of biological sciences 2018;14(5):531-541
Engagement of circular RNA HECW2 in the nonautophagic role of ATG5 implicated in the endothelial-mesenchymal transition.
Yang L, Han B, Zhang Y, Bai Y, Chao J, Hu G, Yao H
Autophagy 2018;14(3):404-418
Autophagy 2018;14(3):404-418
Autosomal dominant retinitis pigmentosa-associated gene PRPF8 is essential for hypoxia-induced mitophagy through regulating ULK1 mRNA splicing.
Xu G, Li T, Chen J, Li C, Zhao H, Yao C, Dong H, Wen K, Wang K, Zhao J, Xia Q, Zhou T, Zhang H, Gao P, Li A, Pan X
Autophagy 2018;14(10):1818-1830
Autophagy 2018;14(10):1818-1830
Combined inhibition of autophagy and Nrf2 signaling augments bortezomib-induced apoptosis by increasing ROS production and ER stress in pancreatic cancer cells.
Li X, Liang M, Jiang J, He R, Wang M, Guo X, Shen M, Qin R
International journal of biological sciences 2018;14(10):1291-1305
International journal of biological sciences 2018;14(10):1291-1305
Dexmedetomidine attenuates the propofol-induced long-term neurotoxicity in the developing brain of rats by enhancing the PI3K/Akt signaling pathway.
Xiao Y, Zhou L, Tu Y, Li Y, Liang Y, Zhang X, Lv J, Zhong Y, Xie Y
Neuropsychiatric disease and treatment 2018;14:2191-2206
Neuropsychiatric disease and treatment 2018;14:2191-2206
Wenyang Huazhuo Tongluo formula inhibits fibrosis via suppressing Wnt/β-catenin signaling pathway in a Bleomycin-induced systemic sclerosis mouse model.
Wang Q, Zang W, Han L, Yang L, Ye S, Ouyang J, Zhang C, Bi Y, Zhang C, Bian H
Chinese medicine 2018;13:17
Chinese medicine 2018;13:17
Notch inhibitor can attenuate apparent diffusion coefficient and improve neurological function through downregulating NOX2-ROS in severe traumatic brain injury.
Zhang HM, Chen W, Liu RN, Zhao Y
Drug design, development and therapy 2018;12:3847-3854
Drug design, development and therapy 2018;12:3847-3854
Realgar, a traditional Chinese medicine, induces apoptosis of HPV16-positive cervical cells through a HPV16 E7-related pathway.
Ding W, Ji T, Xiong W, Li T, Pu D, Liu R
Drug design, development and therapy 2018;12:3459-3469
Drug design, development and therapy 2018;12:3459-3469
Zoledronate inhibits fibroblasts' proliferation and activation via targeting TGF-β signaling pathway.
Zhao Z, Shen W, Zhu H, Lin L, Jiang G, Zhu Y, Song H, Wu L
Drug design, development and therapy 2018;12:3021-3031
Drug design, development and therapy 2018;12:3021-3031
Gestational Exposure to Particulate Matter 2.5 (PM2.5) Leads to Spatial Memory Dysfunction and Neurodevelopmental Impairment in Hippocampus of Mice Offspring.
Zheng X, Wang X, Wang T, Zhang H, Wu H, Zhang C, Yu L, Guan Y
Frontiers in neuroscience 2018;12:1000
Frontiers in neuroscience 2018;12:1000
EDIL3 depletion suppress epithelial-mesenchymal transition of lens epithelial cells via transforming growth factor β pathway.
Zhang R, Wei YH, Zhao CY, Song HY, Shen N, Cui X, Gao X, Qi ZT, Zhong M, Shen W
International journal of ophthalmology 2018;11(1):18-24
International journal of ophthalmology 2018;11(1):18-24
Endothelial Monocyte-Activating Polypeptide-II Induces BNIP3-Mediated Mitophagy to Enhance Temozolomide Cytotoxicity of Glioma Stem Cells via Down-Regulating MiR-24-3p.
Zhang J, Liu L, Xue Y, Ma Y, Liu X, Li Z, Li Z, Liu Y
Frontiers in molecular neuroscience 2018;11:92
Frontiers in molecular neuroscience 2018;11:92
Brevilin A promotes oxidative stress and induces mitochondrial apoptosis in U87 glioblastoma cells.
Wang J, Li M, Cui X, Lv D, Jin L, Khan M, Ma T
OncoTargets and therapy 2018;11:7031-7040
OncoTargets and therapy 2018;11:7031-7040
MiR-429 Regulated by Endothelial Monocyte Activating Polypeptide-II (EMAP-II) Influences Blood-Tumor Barrier Permeability by Inhibiting the Expressions of ZO-1, Occludin and Claudin-5.
Chen L, Xue Y, Zheng J, Liu X, Liu J, Chen J, Li Z, Xi Z, Teng H, Wang P, Liu L, Liu Y
Frontiers in molecular neuroscience 2018;11:35
Frontiers in molecular neuroscience 2018;11:35
STAT3 induces colorectal carcinoma progression through a novel miR-572-MOAP-1 pathway.
Wang N, He X, Zhou R, Jia G, Qiao Q
OncoTargets and therapy 2018;11:3475-3484
OncoTargets and therapy 2018;11:3475-3484
Hypoxic Preconditioning Maintains GLT-1 Against Transient Global Cerebral Ischemia Through Upregulating Cx43 and Inhibiting c-Src.
Li K, Zhou H, Zhan L, Shi Z, Sun W, Liu D, Liu L, Liang D, Tan Y, Xu W, Xu E
Frontiers in molecular neuroscience 2018;11:344
Frontiers in molecular neuroscience 2018;11:344
Cosmosiin Increases ADAM10 Expression via Mechanisms Involving 5'UTR and PI3K Signaling.
Min Z, Tang Y, Hu XT, Zhu BL, Ma YL, Zha JS, Deng XJ, Yan Z, Chen GJ
Frontiers in molecular neuroscience 2018;11:198
Frontiers in molecular neuroscience 2018;11:198
Transcriptional Repression of p53 by PAX3 Contributes to Gliomagenesis and Differentiation of Glioma Stem Cells.
Zhu H, Wang H, Huang Q, Liu Q, Guo Y, Lu J, Li X, Xue C, Han Q
Frontiers in molecular neuroscience 2018;11:187
Frontiers in molecular neuroscience 2018;11:187
Characteristics of Sinus Fungus Ball: A Unique Form of Rhinosinusitis.
Jiang RS, Huang WC, Liang KL
Clinical medicine insights. Ear, nose and throat 2018;11:1179550618792254
Clinical medicine insights. Ear, nose and throat 2018;11:1179550618792254
GPX3 suppresses tumor migration and invasion via the FAK/AKT pathway in esophageal squamous cell carcinoma.
Zhu X, Wang J, Li L, Deng L, Wang J, Liu L, Zeng R, Wang Q, Zheng Y
American journal of translational research 2018;10(6):1908-1920
American journal of translational research 2018;10(6):1908-1920
NADH protect against radiation enteritis by enhancing autophagy and inhibiting inflammation through PI3K/AKT pathway.
Wang JT, Xie WQ, Liu FQ, Bi Y, Zhu XJ, Wang QE, Zheng YF
American journal of translational research 2018;10(6):1713-1721
American journal of translational research 2018;10(6):1713-1721
Reduced selenium-binding protein 1 correlates with a poor prognosis in intrahepatic cholangiocarcinoma and promotes the cell epithelial-mesenchymal transition.
Zhang XY, Gao PT, Yang X, Cai JB, Ding GY, Zhu XD, Ji Y, Shi GM, Shen YH, Zhou J, Fan J, Sun HC, Yang LX, Huang C
American journal of translational research 2018;10(11):3567-3578
American journal of translational research 2018;10(11):3567-3578
miR-125a-5p suppresses colorectal cancer progression by targeting VEGFA.
Yang X, Qiu J, Kang H, Wang Y, Qian J
Cancer management and research 2018;10:5839-5853
Cancer management and research 2018;10:5839-5853
Non-coding RNA NEAT1/miR-214-3p contribute to doxorubicin resistance of urothelial bladder cancer preliminary through the Wnt/β-catenin pathway.
Guo Y, Zhang H, Xie D, Hu X, Song R, Zhu L
Cancer management and research 2018;10:4371-4380
Cancer management and research 2018;10:4371-4380
Inhibition of Cathepsins B Induces Neuroprotection Against Secondary Degeneration in Ipsilateral Substantia Nigra After Focal Cortical Infarction in Adult Male Rats.
Zuo X, Hou Q, Jin J, Chen X, Zhan L, Tang Y, Shi Z, Sun W, Xu E
Frontiers in aging neuroscience 2018;10:125
Frontiers in aging neuroscience 2018;10:125
The transcription factor C/EBP α controls the role of cystatin F during the differentiation of monocytes to macrophages.
Dautović E, Perišić Nanut M, Softić A, Kos J
European journal of cell biology 2018 Sep;97(7):463-473
European journal of cell biology 2018 Sep;97(7):463-473
Comparative proteomics reveals the neurotoxicity mechanism of ER stressors tunicamycin and dithiothreitol.
Ren B, Wang Y, Wang H, Wu Y, Li J, Tian J
Neurotoxicology 2018 Sep;68:25-37
Neurotoxicology 2018 Sep;68:25-37
Gemcitabine induces apoptosis and autophagy via the AMPK/mTOR signaling pathway in pancreatic cancer cells.
Zhu J, Chen Y, Ji Y, Yu Y, Jin Y, Zhang X, Zhou J
Biotechnology and applied biochemistry 2018 Sep;65(5):665-671
Biotechnology and applied biochemistry 2018 Sep;65(5):665-671
Sex differences in the effect of cannabinoid type 1 receptor deletion on locus coeruleus-norepinephrine neurons and corticotropin releasing factor-mediated responses.
Wyrofsky RR, Reyes BAS, Yu D, Kirby LG, Van Bockstaele EJ
The European journal of neuroscience 2018 Sep;48(5):2118-2138
The European journal of neuroscience 2018 Sep;48(5):2118-2138
The suppressive effect of soluble Klotho on fibroblastic growth factor 23 synthesis in UMR-106 osteoblast-like cells.
Ma L, Gao M, Wu L, Zhao X, Mao H, Xing C
Cell biology international 2018 Sep;42(9):1270-1274
Cell biology international 2018 Sep;42(9):1270-1274
Downregulation of TRIM58 expression is associated with a poor patient outcome and enhances colorectal cancer cell invasion.
Liu M, Zhang X, Cai J, Li Y, Luo Q, Wu H, Yang Z, Wang L, Chen D
Oncology reports 2018 Sep;40(3):1251-1260
Oncology reports 2018 Sep;40(3):1251-1260
Interferon Gamma Inhibits CXCL8-Induced Proliferation and Migration of Pancreatic Cancer BxPC-3 Cell Line via a RhoGDI2/Rac1/NF-κB Signaling Pathway.
Zhang M, Ding G, Zhou L, Shen T, Xu X, Zhao T, Jia S, Cao L
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 2018 Sep;38(9):413-422
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 2018 Sep;38(9):413-422
Selective Actionable and Druggable Protein Kinases Drive the Progression of Neuroendocrine Prostate Cancer.
Lu C, Qie Y, Liu S, Wu C, Zhang Z, Liu R, Yang K, Hu H, Xu Y
DNA and cell biology 2018 Sep;37(9):758-766
DNA and cell biology 2018 Sep;37(9):758-766
Activation of STAT3 and Bcl-2 and reduction of reactive oxygen species (ROS) promote radioresistance in breast cancer and overcome of radioresistance with niclosamide.
Lu L, Dong J, Wang L, Xia Q, Zhang D, Kim H, Yin T, Fan S, Shen Q
Oncogene 2018 Sep;37(39):5292-5304
Oncogene 2018 Sep;37(39):5292-5304
IL-6 increases podocyte motility via MLC-mediated focal adhesion impairment and cytoskeleton disassembly.
He FF, Bao D, Su H, Wang YM, Lei CT, Zhang CY, Ye C, Tang H, Wan C, You CQ, Zhang J, Xiong J, Zhang C
Journal of cellular physiology 2018 Sep;233(9):7173-7181
Journal of cellular physiology 2018 Sep;233(9):7173-7181
Epigenetic regulation of megakaryocytic and erythroid differentiation by PHF2 histone demethylase.
Yang J, Ma J, Xiong Y, Wang Y, Jin K, Xia W, Chen Q, Huang J, Zhang J, Jiang N, Jiang S, Ma D
Journal of cellular physiology 2018 Sep;233(9):6841-6852
Journal of cellular physiology 2018 Sep;233(9):6841-6852
The oncogenic potentials and diagnostic significance of long non-coding RNA LINC00310 in breast cancer.
Li J, Peng W, Du L, Yang Q, Wang C, Mo YY
Journal of cellular and molecular medicine 2018 Sep;22(9):4486-4495
Journal of cellular and molecular medicine 2018 Sep;22(9):4486-4495
Stromal expression of JNK1 and VDR is associated with the prognosis of esophageal squamous cell carcinoma.
Bao Y, Zhang S, Guo Y, Wei X, Zhang Y, Yang Y, Zhang H, Ma M, Yang W
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 2018 Sep;20(9):1185-1195
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 2018 Sep;20(9):1185-1195
Protein arginine methyltransferase 5-mediated epigenetic silencing of IRX1 contributes to tumorigenicity and metastasis of gastric cancer.
Liu X, Zhang J, Liu L, Jiang Y, Ji J, Yan R, Zhu Z, Yu Y
Biochimica et biophysica acta. Molecular basis of disease 2018 Sep;1864(9 Pt B):2835-2844
Biochimica et biophysica acta. Molecular basis of disease 2018 Sep;1864(9 Pt B):2835-2844
UNBS5162 inhibits proliferation of human melanoma cells by inducing apoptosis via the PI3K/Akt pathway.
Shi X, Yang L, Xie J, Zhao Y, Cong J, Li Z, Li H, Cheng X, Fan J
Molecular medicine reports 2018 Sep;18(3):3382-3388
Molecular medicine reports 2018 Sep;18(3):3382-3388
Adenoviral vector-induced silencing of RGMa attenuates blood-brain barrier dysfunction in a rat model of MCAO/reperfusion.
Li M, Wen Y, Zhang R, Xie F, Zhang G, Qin X
Brain research bulletin 2018 Sep;142:54-62
Brain research bulletin 2018 Sep;142:54-62
Role of hepatoma-derived growth factor in promoting de novo lipogenesis and tumorigenesis in hepatocellular carcinoma.
Min X, Wen J, Zhao L, Wang K, Li Q, Huang G, Liu J, Zhao X
Molecular oncology 2018 Sep;12(9):1480-1497
Molecular oncology 2018 Sep;12(9):1480-1497
Long noncoding RNA LINC00460 targets miR-539/MMP-9 to promote meningioma progression and metastasis.
Xing H, Wang S, Li Q, Ma Y, Sun P
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Sep;105:677-682
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Sep;105:677-682
USP4 positively regulates RLR-induced NF-κB activation by targeting TRAF6 for K48-linked deubiquitination and inhibits enterovirus 71 replication.
Xu C, Peng Y, Zhang Q, Xu XP, Kong XM, Shi WF
Scientific reports 2018 Sep 7;8(1):13418
Scientific reports 2018 Sep 7;8(1):13418
FOXC1 induces cancer stem cell-like properties through upregulation of beta-catenin in NSCLC.
Cao S, Wang Z, Gao X, He W, Cai Y, Chen H, Xu R
Journal of experimental & clinical cancer research : CR 2018 Sep 6;37(1):220
Journal of experimental & clinical cancer research : CR 2018 Sep 6;37(1):220
De Novo Mutations of CCNK Cause a Syndromic Neurodevelopmental Disorder with Distinctive Facial Dysmorphism.
Fan Y, Yin W, Hu B, Kline AD, Zhang VW, Liang D, Sun Y, Wang L, Tang S, Powis Z, Li L, Yan H, Shi Z, Yang X, Chen Y, Wang J, Jiang Y, Tan H, Gu X, Wu L, Yu Y
American journal of human genetics 2018 Sep 6;103(3):448-455
American journal of human genetics 2018 Sep 6;103(3):448-455
LINC00470 Coordinates the Epigenetic Regulation of ELFN2 to Distract GBM Cell Autophagy.
Liu C, Fu H, Liu X, Lei Q, Zhang Y, She X, Liu Q, Liu Q, Sun Y, Li G, Wu M
Molecular therapy : the journal of the American Society of Gene Therapy 2018 Sep 5;26(9):2267-2281
Molecular therapy : the journal of the American Society of Gene Therapy 2018 Sep 5;26(9):2267-2281
Cationic Polymeric Nanoparticle Delivering CCR2 siRNA to Inflammatory Monocytes for Tumor Microenvironment Modification and Cancer Therapy.
Shen S, Zhang Y, Chen KG, Luo YL, Wang J
Molecular pharmaceutics 2018 Sep 4;15(9):3642-3653
Molecular pharmaceutics 2018 Sep 4;15(9):3642-3653
A new meroterpenoid functions as an anti-tumor agent in hepatoma cells by downregulating mTOR activation and inhibiting EMT.
Wan H, Li J, Zhang K, Zou X, Ge L, Zhu F, Zhou H, Gong M, Wang T, Chen D, Peng S, Zhou B, Zeng X
Scientific reports 2018 Sep 3;8(1):13152
Scientific reports 2018 Sep 3;8(1):13152
Long noncoding RNA MIR31HG inhibits hepatocellular carcinoma proliferation and metastasis by sponging microRNA-575 to modulate ST7L expression.
Yan S, Tang Z, Chen K, Liu Y, Yu G, Chen Q, Dang H, Chen F, Ling J, Zhu L, Huang A, Tang H
Journal of experimental & clinical cancer research : CR 2018 Sep 3;37(1):214
Journal of experimental & clinical cancer research : CR 2018 Sep 3;37(1):214
Covalent inhibitors of EGFR family protein kinases induce degradation of human Tribbles 2 (TRIB2) pseudokinase in cancer cells.
Foulkes DM, Byrne DP, Yeung W, Shrestha S, Bailey FP, Ferries S, Eyers CE, Keeshan K, Wells C, Drewry DH, Zuercher WJ, Kannan N, Eyers PA
Science signaling 2018 Sep 25;11(549)
Science signaling 2018 Sep 25;11(549)
Distinct multilevel misregulations of Parkin and PINK1 revealed in cell and animal models of TDP-43 proteinopathy.
Sun X, Duan Y, Qin C, Li JC, Duan G, Deng X, Ni J, Cao X, Xiang K, Tian K, Chen CH, Li A, Fang Y
Cell death & disease 2018 Sep 20;9(10):953
Cell death & disease 2018 Sep 20;9(10):953
Targeting Epigenetic Crosstalk as a Therapeutic Strategy for EZH2-Aberrant Solid Tumors.
Huang X, Yan J, Zhang M, Wang Y, Chen Y, Fu X, Wei R, Zheng XL, Liu Z, Zhang X, Yang H, Hao B, Shen YY, Su Y, Cong X, Huang M, Tan M, Ding J, Geng M
Cell 2018 Sep 20;175(1):186-199.e19
Cell 2018 Sep 20;175(1):186-199.e19
Anti-breast-Cancer Activity Exerted by β-Sitosterol-d-glucoside from Sweet Potato via Upregulation of MicroRNA-10a and via the PI3K-Akt Signaling Pathway.
Xu H, Li Y, Han B, Li Z, Wang B, Jiang P, Zhang J, Ma W, Zhou D, Li X, Ye X
Journal of agricultural and food chemistry 2018 Sep 19;66(37):9704-9718
Journal of agricultural and food chemistry 2018 Sep 19;66(37):9704-9718
Postinfarction Hearts Are Protected by Premature Senescent Cardiomyocytes Via GATA 4-Dependent CCN 1 Secretion.
Cui S, Xue L, Yang F, Dai S, Han Z, Liu K, Liu B, Yuan Q, Cui Z, Zhang Y, Xu F, Chen Y
Journal of the American Heart Association 2018 Sep 18;7(18):e009111
Journal of the American Heart Association 2018 Sep 18;7(18):e009111
IL-13 and IL-13Rα1 are overexpressed in extranodal natural killer/T cell lymphoma and mediate tumor cell proliferation.
Zhang Y, Li C, Zhang M, Li Z
Biochemical and biophysical research communications 2018 Sep 18;503(4):2715-2720
Biochemical and biophysical research communications 2018 Sep 18;503(4):2715-2720
Non-canonical NF-κB Antagonizes STING Sensor-Mediated DNA Sensing in Radiotherapy.
Hou Y, Liang H, Rao E, Zheng W, Huang X, Deng L, Zhang Y, Yu X, Xu M, Mauceri H, Arina A, Weichselbaum RR, Fu YX
Immunity 2018 Sep 18;49(3):490-503.e4
Immunity 2018 Sep 18;49(3):490-503.e4
Mesenchymal stem cells alleviate experimental autoimmune cholangitis through immunosuppression and cytoprotective function mediated by galectin-9.
Fan J, Tang X, Wang Q, Zhang Z, Wu S, Li W, Liu S, Yao G, Chen H, Sun L
Stem cell research & therapy 2018 Sep 17;9(1):237
Stem cell research & therapy 2018 Sep 17;9(1):237
TPC2 mediates autophagy progression and extracellular vesicle secretion in cancer cells.
Sun W, Yue J
Experimental cell research 2018 Sep 15;370(2):478-489
Experimental cell research 2018 Sep 15;370(2):478-489
Rab7 empowers renal tubular epithelial cells with autophagy-mediated protection against albumin-induced injury.
Liu L, Li Y, Wang Z, Ding F, Cheng Z, Xu Q, Cai Y, Limbu MH, Yang Y, Liu B, Chen P
Experimental cell research 2018 Sep 15;370(2):198-207
Experimental cell research 2018 Sep 15;370(2):198-207
Interaction of estrogen receptor β5 and interleukin 6 receptor in the progression of non-small cell lung cancer.
Tang H, Bai Y, Xiong L, Zhang L, Wei Y, Zhu M, Wu X, Long D, Yang J, Yu L, Xu S, Zhao J
Journal of cellular biochemistry 2018 Sep 14;
Journal of cellular biochemistry 2018 Sep 14;
Human Cytomegalovirus Immediate Early 1 Protein Causes Loss of SOX2 from Neural Progenitor Cells by Trapping Unphosphorylated STAT3 in the Nucleus.
Wu CC, Jiang X, Wang XZ, Liu XJ, Li XJ, Yang B, Ye HQ, Harwardt T, Jiang M, Xia HM, Wang W, Britt WJ, Paulus C, Nevels M, Luo MH
Journal of virology 2018 Sep 1;92(17)
Journal of virology 2018 Sep 1;92(17)
The developmental transcription factor IRF6 attenuates ABCG2 gene expression and distinctively reverses stemness phenotype in nasopharyngeal carcinoma.
Xu L, Huang TJ, Hu H, Wang MY, Shi SM, Yang Q, Lin F, Qiang YY, Mei Y, Lang YH, Li CZ, Peng LX, Zheng LS, Huang JL, Li XJ, Zhang SJ, Qian CN, Huang BJ
Cancer letters 2018 Sep 1;431:230-243
Cancer letters 2018 Sep 1;431:230-243
Spinal interleukin-10 produces antinociception in neuropathy through microglial β-endorphin expression, separated from antineuroinflammation.
Wu HY, Mao XF, Tang XQ, Ali U, Apryani E, Liu H, Li XY, Wang YX
Brain, behavior, and immunity 2018 Oct;73:504-519
Brain, behavior, and immunity 2018 Oct;73:504-519
MALAT1 promotes the colorectal cancer malignancy by increasing DCP1A expression and miR203 downregulation.
Wu C, Zhu X, Tao K, Liu W, Ruan T, Wan W, Zhang C, Zhang W
Molecular carcinogenesis 2018 Oct;57(10):1421-1431
Molecular carcinogenesis 2018 Oct;57(10):1421-1431
MiR-616-3p modulates cell proliferation and migration through targeting tissue factor pathway inhibitor 2 in preeclampsia.
Xu Y, Wu D, Jiang Z, Zhang Y, Wang S, Ma Z, Hui B, Wang J, Qian W, Ge Z, Sun L
Cell proliferation 2018 Oct;51(5):e12490
Cell proliferation 2018 Oct;51(5):e12490
The effects of HAP and macrophage cells to the expression of inflammatory factors and apoptosis in HK-2 cells of vitro co-cultured system.
Yu J, Deng Y, Tao Z, Liang W, Guan X, Wu J, Ning X, Liu Y, Liu Q, He Z
Urolithiasis 2018 Oct;46(5):429-443
Urolithiasis 2018 Oct;46(5):429-443
Effects of NMDAR Antagonist on the Regulation of P-MARCKS Protein to Aβ1-42 Oligomers Induced Neurotoxicity.
Liu Y, Zhang P, Zheng Y, Yang C, Du T, Ge M, Chang X, Duan R, Ma G
Neurochemical research 2018 Oct;43(10):2008-2015
Neurochemical research 2018 Oct;43(10):2008-2015
GPR40 modulates epileptic seizure and NMDA receptor function.
Yang Y, Tian X, Xu D, Zheng F, Lu X, Zhang Y, Ma Y, Li Y, Xu X, Zhu B, Wang X
Science advances 2018 Oct;4(10):eaau2357
Science advances 2018 Oct;4(10):eaau2357
Erythropoietin-producing hepatocellular A7 triggering ovulation indicates a potential beneficial role for polycystic ovary syndrome.
Li S, Zhai J, Liu J, Di F, Sun Y, Li W, Chen ZJ, Du Y
EBioMedicine 2018 Oct;36:539-552
EBioMedicine 2018 Oct;36:539-552
SIRT5 deacylates metabolism-related proteins and attenuates hepatic steatosis in ob/ob mice.
Du Y, Hu H, Qu S, Wang J, Hua C, Zhang J, Wei P, He X, Hao J, Liu P, Yang F, Li T, Wei T
EBioMedicine 2018 Oct;36:347-357
EBioMedicine 2018 Oct;36:347-357
Histone Deacetylase 3 Inhibitor Suppresses Hepatitis C Virus Replication by Regulating Apo-A1 and LEAP-1 Expression.
Zhou Y, Wang Q, Yang Q, Tang J, Xu C, Gai D, Chen X, Chen J
Virologica Sinica 2018 Oct;33(5):418-428
Virologica Sinica 2018 Oct;33(5):418-428
Histone deacetylase inhibitor suberoylanilide hydroxamic acid alleviates liver fibrosis by suppressing the transforming growth factor-β1 signal pathway.
Wang Y, Zhao L, Jiao FZ, Zhang WB, Chen Q, Gong ZJ
Hepatobiliary & pancreatic diseases international : HBPD INT 2018 Oct;17(5):423-429
Hepatobiliary & pancreatic diseases international : HBPD INT 2018 Oct;17(5):423-429
Study on the expression of p53 and MMP-2 in patients with lung cancer after interventional therapy.
Zhang XS, Wang KY, Gao JQ, Li RJ, Guan QB, Song L
Oncology letters 2018 Oct;16(4):4291-4296
Oncology letters 2018 Oct;16(4):4291-4296
Subarachnoid hemorrhage enhances the expression of TDP-43 in the brain of experimental rats and human subjects.
He T, Zuo Y, Ai-Zakwani K, Luo J, Zhu H, Yan XX, Liu F
Experimental and therapeutic medicine 2018 Oct;16(4):3363-3368
Experimental and therapeutic medicine 2018 Oct;16(4):3363-3368
Genistein sensitizes glioblastoma cells to carbon ions via inhibiting DNA-PKcs phosphorylation and subsequently repressing NHEJ and delaying HR repair pathways.
Liu X, Li P, Hirayama R, Niu Y, Liu X, Chen W, Jin X, Zhang P, Ye F, Zhao T, Liu B, Li Q
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 2018 Oct;129(1):84-94
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 2018 Oct;129(1):84-94
MicroRNA-23a-5p promotes atherosclerotic plaque progression and vulnerability by repressing ATP-binding cassette transporter A1/G1 in macrophages.
Yang S, Ye ZM, Chen S, Luo XY, Chen SL, Mao L, Li Y, Jin H, Yu C, Xiang FX, Xie MX, Chang J, Xia YP, Hu B
Journal of molecular and cellular cardiology 2018 Oct;123:139-149
Journal of molecular and cellular cardiology 2018 Oct;123:139-149
Long non-coding RNA LINC00222 regulates GSK3β activity and promotes cell apoptosis in lung adenocarcinoma.
Zhang H, Wang Y, Lu J, Zhao Y
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Oct;106:755-762
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Oct;106:755-762
MicroRNA-139-3p regulates osteoblast differentiation and apoptosis by targeting ELK1 and interacting with long noncoding RNA ODSM.
Wang Y, Wang K, Hu Z, Zhou H, Zhang L, Wang H, Li G, Zhang S, Cao X, Shi F
Cell death & disease 2018 Oct 31;9(11):1107
Cell death & disease 2018 Oct 31;9(11):1107
The effects of lncRNA MALAT1 on proliferation, invasion and migration in colorectal cancer through regulating SOX9.
Xu Y, Zhang X, Hu X, Zhou W, Zhang P, Zhang J, Yang S, Liu Y
Molecular medicine (Cambridge, Mass.) 2018 Oct 3;24(1):52
Molecular medicine (Cambridge, Mass.) 2018 Oct 3;24(1):52
Apigenin suppresses PD-L1 expression in melanoma and host dendritic cells to elicit synergistic therapeutic effects.
Xu L, Zhang Y, Tian K, Chen X, Zhang R, Mu X, Wu Y, Wang D, Wang S, Liu F, Wang T, Zhang J, Liu S, Zhang Y, Tu C, Liu H
Journal of experimental & clinical cancer research : CR 2018 Oct 29;37(1):261
Journal of experimental & clinical cancer research : CR 2018 Oct 29;37(1):261
Salvianolic Acid B-Alleviated Angiotensin II Induces Cardiac Fibrosis by Suppressing NF-κB Pathway In Vitro.
Wang C, Luo H, Xu Y, Tao L, Chang C, Shen X
Medical science monitor : international medical journal of experimental and clinical research 2018 Oct 26;24:7654-7664
Medical science monitor : international medical journal of experimental and clinical research 2018 Oct 26;24:7654-7664
MicroRNA-9 modified bone marrow-derived mesenchymal stem cells (BMSCs) repair severe acute pancreatitis (SAP) via inducing angiogenesis in rats.
Qian D, Song G, Ma Z, Wang G, Jin L, Hu M, Song Z, Wang X
Stem cell research & therapy 2018 Oct 25;9(1):282
Stem cell research & therapy 2018 Oct 25;9(1):282
Up-regulated miR-133a orchestrates epithelial-mesenchymal transition of airway epithelial cells.
Chen L, He X, Xie Y, Huang Y, Wolff DW, Abel PW, Tu Y
Scientific reports 2018 Oct 19;8(1):15543
Scientific reports 2018 Oct 19;8(1):15543
Neuroinflammation is induced by tongue-instilled ZnO nanoparticles via the Ca2+-dependent NF-κB and MAPK pathways.
Liang H, Chen A, Lai X, Liu J, Wu J, Kang Y, Wang X, Shao L
Particle and fibre toxicology 2018 Oct 19;15(1):39
Particle and fibre toxicology 2018 Oct 19;15(1):39
Enhanced anti-obesity effects of bacterial cellulose combined with konjac glucomannan in high-fat diet-fed C57BL/6J mice.
Zhai X, Lin D, Zhao Y, Li W, Yang X
Food & function 2018 Oct 17;9(10):5260-5272
Food & function 2018 Oct 17;9(10):5260-5272
Immune Activation of RAW264.7 Macrophages by Low Molecular Weight Fucoidan Extracted from New Zealand Undaria pinnatifida.
Bi D, Yu B, Han Q, Lu J, White WL, Lai Q, Cai N, Luo W, Gu L, Li S, Xu H, Hu Z, Nie S, Xu X
Journal of agricultural and food chemistry 2018 Oct 17;66(41):10721-10728
Journal of agricultural and food chemistry 2018 Oct 17;66(41):10721-10728
Cd induces G2/M cell cycle arrest by up-regulating miR-133b via directly targeting PPP2R2D in L02 hepatocytes.
Zhang Y, Xiao F, Zhong C, Zeng M, Zou L
Metallomics : integrated biometal science 2018 Oct 17;10(10):1510-1523
Metallomics : integrated biometal science 2018 Oct 17;10(10):1510-1523
Biased antagonism of CXCR4 avoids antagonist tolerance.
Hitchinson B, Eby JM, Gao X, Guite-Vinet F, Ziarek JJ, Abdelkarim H, Lee Y, Okamoto Y, Shikano S, Majetschak M, Heveker N, Volkman BF, Tarasova NI, Gaponenko V
Science signaling 2018 Oct 16;11(552)
Science signaling 2018 Oct 16;11(552)
GAPDH rs1136666 SNP indicates a high risk of Parkinson's disease.
Ping Z, Xiaomu W, Xufang X, Wenfeng C, Liang S, Tao W
Neuroscience letters 2018 Oct 15;685:55-62
Neuroscience letters 2018 Oct 15;685:55-62
PARP1 interacts with STAT3 and retains active phosphorylated-STAT3 in nucleus during pathological myocardial hypertrophy.
Wang L, Li Z, Tan Y, Li Q, Yang H, Wang P, Lu J, Liu P
Molecular and cellular endocrinology 2018 Oct 15;474:137-150
Molecular and cellular endocrinology 2018 Oct 15;474:137-150
The Age-dependent Elevation of miR-335-3p Leads to Reduced Cholesterol and Impaired Memory in Brain.
Raihan O, Brishti A, Molla MR, Li W, Zhang Q, Xu P, Khan MI, Zhang J, Liu Q
Neuroscience 2018 Oct 15;390:160-173
Neuroscience 2018 Oct 15;390:160-173
Identification of the UBA2-WTIP fusion gene in acute myeloid leukemia.
Lu X, Zhuang H, Yu Q, Zhang X, Wu Z, Zhang L, Xu Y, Wu B, Yang L, Ma A, Gan X, Yu X, Shen J, Xu R
Experimental cell research 2018 Oct 15;371(2):409-416
Experimental cell research 2018 Oct 15;371(2):409-416
Role of p62/SQSTM1 in lipopolysaccharide (LPS)-induced mucus hypersecretion in bronchial epithelial cells.
Wu Y, Li Y, Wang B, He X, Li Y, Wu B, Yu G, Wang H, Xu B
Life sciences 2018 Oct 15;211:270-278
Life sciences 2018 Oct 15;211:270-278
Bowman‒Birk Inhibitor Suppresses Herpes Simplex Virus Type 2 Infection of Human Cervical Epithelial Cells.
Liu Y, Xu XQ, Zhang B, Gu J, Meng FZ, Liu H, Zhou L, Wang X, Hou W, Ho WZ
Viruses 2018 Oct 12;10(10)
Viruses 2018 Oct 12;10(10)
Mechanism of piR-DQ590027/MIR17HG regulating the permeability of glioma conditioned normal BBB.
Leng X, Ma J, Liu Y, Shen S, Yu H, Zheng J, Liu X, Liu L, Chen J, Zhao L, Ruan X, Xue Y
Journal of experimental & clinical cancer research : CR 2018 Oct 11;37(1):246
Journal of experimental & clinical cancer research : CR 2018 Oct 11;37(1):246
Isopsoralen Enhanced Osteogenesis by Targeting AhR/ERα.
Ge L, Cui Y, Cheng K, Han J
Molecules (Basel, Switzerland) 2018 Oct 11;23(10)
Molecules (Basel, Switzerland) 2018 Oct 11;23(10)
Deleting MyD88 signaling in myeloid cells promotes development of adenocarcinomas of the colon.
Song J, Chen Z, Geng T, Wang M, Yi S, Liu K, Zhou W, Gao J, Song W, Tang H
Cancer letters 2018 Oct 1;433:65-75
Cancer letters 2018 Oct 1;433:65-75
Alantolactone induces apoptosis and improves chemosensitivity of pancreatic cancer cells by impairment of autophagy-lysosome pathway via targeting TFEB.
He R, Shi X, Zhou M, Zhao Y, Pan S, Zhao C, Guo X, Wang M, Li X, Qin R
Toxicology and applied pharmacology 2018 Oct 1;356:159-171
Toxicology and applied pharmacology 2018 Oct 1;356:159-171
Regulation of osteogenesis by micro/nano hierarchical titanium surfaces through a Rock-Wnt5a feedback loop.
Yu Y, Shen X, Liu J, Hu Y, Ran Q, Mu C, Cai K
Colloids and surfaces. B, Biointerfaces 2018 Oct 1;170:1-10
Colloids and surfaces. B, Biointerfaces 2018 Oct 1;170:1-10
The protective effect of melatonin on brain ischemia and reperfusion in rats and humans: In vivo assessment and a randomized controlled trial.
Zhao Z, Lu C, Li T, Wang W, Ye W, Zeng R, Ni L, Lai Z, Wang X, Liu C
Journal of pineal research 2018 Nov;65(4):e12521
Journal of pineal research 2018 Nov;65(4):e12521
The sialyltransferase ST3Gal3 facilitates the receptivity of the uterine endometrium in vitro and in vivo.
Yu M, Wang H, Liu J, Qin H, Liu S, Yan Q
FEBS letters 2018 Nov;592(22):3696-3707
FEBS letters 2018 Nov;592(22):3696-3707
RNA interference of long noncoding RNA HOTAIR suppresses autophagy and promotes apoptosis and sensitivity to cisplatin in oral squamous cell carcinoma.
Wang X, Liu W, Wang P, Li S
Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology 2018 Nov;47(10):930-937
Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology 2018 Nov;47(10):930-937
HMGB1 knock-down promoting tumor cells viability and arrest pro-apoptotic proteins via Stat3/NFκB in HepG2 cells.
Alduais S, Alduais Y, Wu X, Li H, Mao J
BioFactors (Oxford, England) 2018 Nov;44(6):570-576
BioFactors (Oxford, England) 2018 Nov;44(6):570-576
KLF5 promotes the tumorigenesis and metastatic potential of thyroid cancer cells through the NF-κB signaling pathway.
Ma Y, Wang Q, Liu F, Ma X, Wu L, Guo F, Zhao S, Huang F, Qin G
Oncology reports 2018 Nov;40(5):2608-2618
Oncology reports 2018 Nov;40(5):2608-2618
Microtubule associated protein 4 phosphorylation leads to pathological cardiac remodeling in mice.
Li L, Zhang Q, Zhang X, Zhang J, Wang X, Ren J, Jia J, Zhang D, Jiang X, Zhang J, Mei H, Chen B, Hu J, Huang Y
EBioMedicine 2018 Nov;37:221-235
EBioMedicine 2018 Nov;37:221-235
METTL3-mediated N6-methyladenosine mRNA modification enhances long-term memory consolidation.
Zhang Z, Wang M, Xie D, Huang Z, Zhang L, Yang Y, Ma D, Li W, Zhou Q, Yang YG, Wang XJ
Cell research 2018 Nov;28(11):1050-1061
Cell research 2018 Nov;28(11):1050-1061
miR-153 inhibits the migration and the tube formation of endothelial cells by blocking the paracrine of angiopoietin 1 in breast cancer cells.
Liang H, Ge F, Xu Y, Xiao J, Zhou Z, Liu R, Chen C
Angiogenesis 2018 Nov;21(4):849-860
Angiogenesis 2018 Nov;21(4):849-860
Silencing of rhomboid domain containing 1 to inhibit the metastasis of human breast cancer cells in vitro.
Huang C, Ji X, Peng Y, Wu M, Wu W, Luo Y, Cheng G, Zhu Y
Iranian journal of basic medical sciences 2018 Nov;21(11):1161-1166
Iranian journal of basic medical sciences 2018 Nov;21(11):1161-1166
Deficiency in augmenter of liver regeneration accelerates liver fibrosis by promoting migration of hepatic stellate cell.
Ai WL, Dong LY, Wang J, Li ZW, Wang X, Gao J, Wu Y, An W
Biochimica et biophysica acta. Molecular basis of disease 2018 Nov;1864(11):3780-3791
Biochimica et biophysica acta. Molecular basis of disease 2018 Nov;1864(11):3780-3791
Boron Affects the Development of the Kidney Through Modulation of Apoptosis, Antioxidant Capacity, and Nrf2 Pathway in the African Ostrich Chicks.
Khaliq H, Jing W, Ke X, Ke-Li Y, Peng-Peng S, Cui L, Wei-Wei Q, Zhixin L, Hua-Zhen L, Hui S, Ju-Ming Z, Ke-Mei P
Biological trace element research 2018 Nov;186(1):226-237
Biological trace element research 2018 Nov;186(1):226-237
Cantharidin inhibits melanoma cell proliferation via the miR‑21‑mediated PTEN pathway.
Mu Z, Sun Q
Molecular medicine reports 2018 Nov;18(5):4603-4610
Molecular medicine reports 2018 Nov;18(5):4603-4610
Protective effects of α‑2‑macroglobulin on human bone marrow mesenchymal stem cells in radiation injury.
Liu Y, Cao W, Kong X, Li J, Chen X, Ge Y, Zhong W, Fang S
Molecular medicine reports 2018 Nov;18(5):4219-4228
Molecular medicine reports 2018 Nov;18(5):4219-4228
Hepatitis B virus X protein promotes epithelial-mesenchymal transition and metastasis in hepatocellular carcinoma cell line HCCLM3 by targeting HMGA2.
Zha Y, Yao Q, Liu JS, Wang YY, Sun WM
Oncology letters 2018 Nov;16(5):5709-5714
Oncology letters 2018 Nov;16(5):5709-5714
METTL3 promotes ovarian carcinoma growth and invasion through the regulation of AXL translation and epithelial to mesenchymal transition.
Hua W, Zhao Y, Jin X, Yu D, He J, Xie D, Duan P
Gynecologic oncology 2018 Nov;151(2):356-365
Gynecologic oncology 2018 Nov;151(2):356-365
Blocking LINC00152 suppresses glioblastoma malignancy by impairing mesenchymal phenotype through the miR-612/AKT2/NF-κB pathway.
Cai J, Zhang J, Wu P, Yang W, Ye Q, Chen Q, Jiang C
Journal of neuro-oncology 2018 Nov;140(2):225-236
Journal of neuro-oncology 2018 Nov;140(2):225-236
Activation of α7 nicotinic acetylcholine receptor alleviates Aβ1-42-induced neurotoxicity via downregulation of p38 and JNK MAPK signaling pathways.
Chang KW, Zong HF, Ma KG, Zhai WY, Yang WN, Hu XD, Xu JH, Chen XL, Ji SF, Qian YH
Neurochemistry international 2018 Nov;120:238-250
Neurochemistry international 2018 Nov;120:238-250
Pathological cyclic strain promotes proliferation of vascular smooth muscle cells via the ACTH/ERK/STAT3 pathway.
Tang X, Liu Y, Xiao Q, Yao Q, Allen M, Wang Y, Gao L, Qi Y, Zhang P
Journal of cellular biochemistry 2018 Nov;119(10):8260-8270
Journal of cellular biochemistry 2018 Nov;119(10):8260-8270
Toll-like receptor 4 shRNA attenuates lipopolysaccharide-induced epithelial-mesenchymal transition of intrahepatic biliary epithelial cells in rats.
Tang S, Jiang X, Wu L, Chen S, Chen L, Jiang J, Yan P, Wang F, Tu K, Wang D, Gu J, Zhao L
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Nov;107:1210-1217
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Nov;107:1210-1217
miR-146b promotes cell proliferation and increases chemosensitivity, but attenuates cell migration and invasion via FBXL10 in ovarian cancer.
Yan M, Yang X, Shen R, Wu C, Wang H, Ye Q, Yang P, Zhang L, Chen M, Wan B, Zhang Q, Xia S, Lu X, Shao G, Zhou X, Yu J, Shao Q
Cell death & disease 2018 Nov 8;9(11):1123
Cell death & disease 2018 Nov 8;9(11):1123
Evaluation of a Potential Clinical Significant Drug-Drug Interaction between Digoxin and Bupropion in Cynomolgus Monkeys.
Shen Y, Yu Y, Lai W, Li S, Xu Z, Jin J, Yan X, Xing H, Chen X, Xiong A, Xia C, He J, Hong K
Pharmaceutical research 2018 Nov 6;36(1):1
Pharmaceutical research 2018 Nov 6;36(1):1
Breed Differences in Pig Liver Esterase (PLE) between Tongcheng (Chinese Local Breed) and Large White Pigs.
Xiao Q, Zhou Q, Yang L, Tian Z, Wang X, Xiao Y, Shi D
Scientific reports 2018 Nov 5;8(1):16364
Scientific reports 2018 Nov 5;8(1):16364
Synergetic and Antagonistic Molecular Effects Mediated by the Feedback Loop of p53 and JNK between Saikosaponin D and SP600125 on Lung Cancer A549 Cells.
Chen X, Liu C, Zhao R, Zhao P, Wu J, Zhou N, Ying M
Molecular pharmaceutics 2018 Nov 5;15(11):4974-4984
Molecular pharmaceutics 2018 Nov 5;15(11):4974-4984
Expression of DEC2 enhances chemosensitivity by inhibiting STAT5A in gastric cancer.
Li H, Ma X, Xiao D, Jia Y, Wang Y
Journal of cellular biochemistry 2018 Nov 28;
Journal of cellular biochemistry 2018 Nov 28;
Vasculogenic mimicry formation in EBV-associated epithelial malignancies.
Xiang T, Lin YX, Ma W, Zhang HJ, Chen KM, He GP, Zhang X, Xu M, Feng QS, Chen MY, Zeng MS, Zeng YX, Feng L
Nature communications 2018 Nov 27;9(1):5009
Nature communications 2018 Nov 27;9(1):5009
Abnormally elevated USP37 expression in breast cancer stem cells regulates stemness, epithelial-mesenchymal transition and cisplatin sensitivity.
Qin T, Li B, Feng X, Fan S, Liu L, Liu D, Mao J, Lu Y, Yang J, Yu X, Zhang Q, Zhang J, Song B, Li M, Li L
Journal of experimental & clinical cancer research : CR 2018 Nov 27;37(1):287
Journal of experimental & clinical cancer research : CR 2018 Nov 27;37(1):287
The Mitochondrial Apoptotic Effectors BAX/BAK Activate Caspase-3 and -7 to Trigger NLRP3 Inflammasome and Caspase-8 Driven IL-1β Activation.
Vince JE, De Nardo D, Gao W, Vince AJ, Hall C, McArthur K, Simpson D, Vijayaraj S, Lindqvist LM, Bouillet P, Rizzacasa MA, Man SM, Silke J, Masters SL, Lessene G, Huang DCS, Gray DHD, Kile BT, Shao F, Lawlor KE
Cell reports 2018 Nov 27;25(9):2339-2353.e4
Cell reports 2018 Nov 27;25(9):2339-2353.e4
Aspergillus fumigatus phospholipase D may enhance reactive oxygen species production by accumulation of histone deacetylase 6.
Yu S, Huo K
Biochemical and biophysical research communications 2018 Nov 2;505(3):651-656
Biochemical and biophysical research communications 2018 Nov 2;505(3):651-656
Tetrachlorobenzoquinone-Induced Nrf2 Confers Neuron-like PC12 Cells Resistance to Endoplasmic Reticulum Stress via Regulating Glutathione Synthesis and Protein Thiol Homeostasis.
Liu Z, Dong W, Yang B, Peng L, Xia X, Pu L, Zhang N, Song E, Song Y
Chemical research in toxicology 2018 Nov 19;31(11):1230-1239
Chemical research in toxicology 2018 Nov 19;31(11):1230-1239
PJA1 Coordinates with the SMC5/6 Complex To Restrict DNA Viruses and Episomal Genes in an Interferon-Independent Manner.
Xu W, Ma C, Zhang Q, Zhao R, Hu D, Zhang X, Chen J, Liu F, Wu K, Liu Y, Wu J
Journal of virology 2018 Nov 15;92(22)
Journal of virology 2018 Nov 15;92(22)
CHCHD2 accumulates in distressed mitochondria and facilitates oligomerization of CHCHD10.
Huang X, Wu BP, Nguyen D, Liu YT, Marani M, Hench J, Bénit P, Kozjak-Pavlovic V, Rustin P, Frank S, Narendra DP
Human molecular genetics 2018 Nov 15;27(22):3881-3900
Human molecular genetics 2018 Nov 15;27(22):3881-3900
Hemopexin reduces blood-brain barrier injury and protects synaptic plasticity in cerebral ischemic rats by promoting EPCs through the HO-1 pathway.
Yang Y, Dong B, Lu J, Wang G, Yu Y
Brain research 2018 Nov 15;1699:177-185
Brain research 2018 Nov 15;1699:177-185
Tannic acid directly targets pyruvate kinase isoenzyme M2 to attenuate colon cancer cell proliferation.
Yang P, Ding GB, Liu W, Fu R, Sajid A, Li Z
Food & function 2018 Nov 14;9(11):5547-5559
Food & function 2018 Nov 14;9(11):5547-5559
Upregulation of circ-UBAP2 predicts poor prognosis and promotes triple-negative breast cancer progression through the miR-661/MTA1 pathway.
Wang S, Li Q, Wang Y, Li X, Wang R, Kang Y, Xue X, Meng R, Wei Q, Feng X
Biochemical and biophysical research communications 2018 Nov 10;505(4):996-1002
Biochemical and biophysical research communications 2018 Nov 10;505(4):996-1002
Astragaloside exerts anti-photoaging effects in UVB-induced premature senescence of rat dermal fibroblasts through enhanced autophagy.
Wen W, Chen J, Ding L, Luo X, Zheng X, Dai Q, Gu Q, Liu C, Liang M, Guo X, Liu P, Li M
Archives of biochemistry and biophysics 2018 Nov 1;657:31-40
Archives of biochemistry and biophysics 2018 Nov 1;657:31-40
Expression of programmed cell death protein 1 (PD-1) and indoleamine 2,3-dioxygenase (IDO) in the tumor microenvironment and in tumor-draining lymph nodes of breast cancer.
Ye Q, Wang C, Xian J, Zhang M, Cao Y, Cao Y
Human pathology 2018 May;75:81-90
Human pathology 2018 May;75:81-90
Progranulin promotes lymphangiogenesis through VEGF-C and is an independent risk factor in human esophageal cancers.
Li G, Dong T, Yang D, Gao A, Luo J, Yang H, Wang L
Human pathology 2018 May;75:116-124
Human pathology 2018 May;75:116-124
MicroRNA-181c promotes Th17 cell differentiation and mediates experimental autoimmune encephalomyelitis.
Zhang Z, Xue Z, Liu Y, Liu H, Guo X, Li Y, Yang H, Zhang L, Da Y, Yao Z, Zhang R
Brain, behavior, and immunity 2018 May;70:305-314
Brain, behavior, and immunity 2018 May;70:305-314
Resveratrol Improves Muscle Atrophy by Modulating Mitochondrial Quality Control in STZ-Induced Diabetic Mice.
Wang D, Sun H, Song G, Yang Y, Zou X, Han P, Li S
Molecular nutrition & food research 2018 May;62(9):e1700941
Molecular nutrition & food research 2018 May;62(9):e1700941
Follicle-stimulating hormone enhances hepatic gluconeogenesis by GRK2-mediated AMPK hyperphosphorylation at Ser485 in mice.
Qi X, Guo Y, Song Y, Yu C, Zhao L, Fang L, Kong D, Zhao J, Gao L
Diabetologia 2018 May;61(5):1180-1192
Diabetologia 2018 May;61(5):1180-1192
CEACAM1 resists hypoxia-induced inhibition of tube formation of human dermal lymphatic endothelial cells.
Xie Q, Chen X, Xu Y, Liang J, Wang F, Liu J
Cellular signalling 2018 May;45:145-152
Cellular signalling 2018 May;45:145-152
Ultrasound Irradiation Combined with Hepatocyte Growth Factor Accelerate the Hepatic Differentiation of Human Bone Marrow Mesenchymal Stem Cells.
Li F, Liu Y, Cai Y, Li X, Bai M, Sun T, Du L
Ultrasound in medicine & biology 2018 May;44(5):1044-1052
Ultrasound in medicine & biology 2018 May;44(5):1044-1052
Effect of placental sex hormone-binding globulin single nucleotide polymorphism rs6259 on protein and function in gestational diabetes mellitus.
Zhang X, Sun L, Jin Z
International journal of molecular medicine 2018 May;41(5):2927-2934
International journal of molecular medicine 2018 May;41(5):2927-2934
Identification of Functional Thyroid Stimulating Hormone Receptor and TSHR Gene Mutations in Hepatocellular Carcinoma.
Shih YL, Huang YH, Lin KH, Chu YD, Yeh CT
Anticancer research 2018 May;38(5):2793-2802
Anticancer research 2018 May;38(5):2793-2802
The E3 ubiquitin ligase Triad1 influences development of Mll-Ell-induced acute myeloid leukemia.
Wang H, Bei L, Shah CA, Huang W, Platanias LC, Eklund EA
Oncogene 2018 May;37(19):2532-2544
Oncogene 2018 May;37(19):2532-2544
LncRNA-PVT1 promotes pancreatic cancer cells proliferation and migration through acting as a molecular sponge to regulate miR-448.
Zhao L, Kong H, Sun H, Chen Z, Chen B, Zhou M
Journal of cellular physiology 2018 May;233(5):4044-4055
Journal of cellular physiology 2018 May;233(5):4044-4055
Antagonism of cortistatin against cyclosporine-induced apoptosis in rat myocardial cells and its effect on myocardial apoptosis gene expression.
Geng L, Wang XT, Yu J, Yang YL
European review for medical and pharmacological sciences 2018 May;22(10):3207-3213
European review for medical and pharmacological sciences 2018 May;22(10):3207-3213
PVT1 regulates the malignant behaviors of human glioma cells by targeting miR-190a-5p and miR-488-3p.
Xue W, Chen J, Liu X, Gong W, Zheng J, Guo X, Liu Y, Liu L, Ma J, Wang P, Li Z, Xue Y
Biochimica et biophysica acta. Molecular basis of disease 2018 May;1864(5 Pt A):1783-1794
Biochimica et biophysica acta. Molecular basis of disease 2018 May;1864(5 Pt A):1783-1794
FTO promotes SREBP1c maturation and enhances CIDEC transcription during lipid accumulation in HepG2 cells.
Chen A, Chen X, Cheng S, Shu L, Yan M, Yao L, Wang B, Huang S, Zhou L, Yang Z, Liu G
Biochimica et biophysica acta. Molecular and cell biology of lipids 2018 May;1863(5):538-548
Biochimica et biophysica acta. Molecular and cell biology of lipids 2018 May;1863(5):538-548
Targeting Polo-like Kinase 1 by a Novel Pyrrole-Imidazole Polyamide-Hoechst Conjugate Suppresses Tumor Growth In Vivo.
Liu K, Fang L, Sun H, Pan Z, Zhang J, Chen J, Shao X, Wang W, Tan Y, Ding Z, Ao L, Wu C, Liu X, Li H, Wang R, Su W, Li H
Molecular cancer therapeutics 2018 May;17(5):988-1002
Molecular cancer therapeutics 2018 May;17(5):988-1002
Liraglutide improves hepatic insulin resistance via the canonical Wnt signaling pathway.
Qin Y, Chen M, Yang Y, Zhou XR, Shao SY, Wang DW, Yuan G
Molecular medicine reports 2018 May;17(5):7372-7380
Molecular medicine reports 2018 May;17(5):7372-7380
Local intra‑articular injection of vascular endothelial growth factor accelerates articular cartilage degeneration in rat osteoarthritis model.
Deng S, Zhou JL, Peng H, Fang HS, Liu F, Weng JQ
Molecular medicine reports 2018 May;17(5):6311-6318
Molecular medicine reports 2018 May;17(5):6311-6318
Cantharidin suppresses cell growth and migration, and activates autophagy in human non-small cell lung cancer cells.
Liu YP, Li L, Xu L, Dai EN, Chen WD
Oncology letters 2018 May;15(5):6527-6532
Oncology letters 2018 May;15(5):6527-6532
M2-specific reduction of CD1d switches NKT cell-mediated immune responses and triggers metaflammation in adipose tissue.
Zhang H, Xue R, Zhu S, Fu S, Chen Z, Zhou R, Tian Z, Bai L
Cellular & molecular immunology 2018 May;15(5):506-517
Cellular & molecular immunology 2018 May;15(5):506-517
Cardioprotection of CAPE-oNO2 against myocardial ischemia/reperfusion induced ROS generation via regulating the SIRT1/eNOS/NF-κB pathway in vivo and in vitro.
Li D, Wang X, Huang Q, Li S, Zhou Y, Li Z
Redox biology 2018 May;15:62-73
Redox biology 2018 May;15:62-73
The glucagon-like peptide-1 (GLP-1) analog liraglutide attenuates renal fibrosis.
Li YK, Ma DX, Wang ZM, Hu XF, Li SL, Tian HZ, Wang MJ, Shu YW, Yang J
Pharmacological research 2018 May;131:102-111
Pharmacological research 2018 May;131:102-111
Diallyl Trisulfide inhibits breast cancer stem cells via suppression of Wnt/β-catenin pathway.
Li X, Meng Y, Xie C, Zhu J, Wang X, Li Y, Geng S, Wu J, Zhong C, Li M
Journal of cellular biochemistry 2018 May;119(5):4134-4141
Journal of cellular biochemistry 2018 May;119(5):4134-4141
Activation of AMPK by simvastatin inhibited breast tumor angiogenesis via impeding HIF-1α-induced pro-angiogenic factor.
Wang JC, Li XX, Sun X, Li GY, Sun JL, Ye YP, Cong LL, Li WM, Lu SY, Feng J, Liu PJ
Cancer science 2018 May;109(5):1627-1637
Cancer science 2018 May;109(5):1627-1637
Chromosome Segregation Is Biased by Kinetochore Size.
Drpic D, Almeida AC, Aguiar P, Renda F, Damas J, Lewin HA, Larkin DM, Khodjakov A, Maiato H
Current biology : CB 2018 May 7;28(9):1344-1356.e5
Current biology : CB 2018 May 7;28(9):1344-1356.e5
CysLTR1 Blockage Ameliorates Liver Injury Caused by Aluminum-Overload via PI3K/AKT/mTOR-Mediated Autophagy Activation in Vivo and in Vitro.
Hu C, Yang J, He Q, Luo Y, Chen Z, Yang L, Yi H, Li H, Xia H, Ran D, Yang Y, Zhang J, Li Y, Wang H
Molecular pharmaceutics 2018 May 7;15(5):1996-2006
Molecular pharmaceutics 2018 May 7;15(5):1996-2006
Interleukin-23 promotes the migration and invasion of gastric cancer cells by inducing epithelial-to-mesenchymal transition via the STAT3 pathway.
Xu X, Yang C, Chen J, Liu J, Li P, Shi Y, Yu P
Biochemical and biophysical research communications 2018 May 5;499(2):273-278
Biochemical and biophysical research communications 2018 May 5;499(2):273-278
Dysregulation of tristetraprolin and human antigen R promotes gastric cancer progressions partly by upregulation of the high-mobility group box 1.
Wang H, Chen Y, Guo J, Shan T, Deng K, Chen J, Cai L, Zhou H, Zhao Q, Jin S, Xia J
Scientific reports 2018 May 4;8(1):7080
Scientific reports 2018 May 4;8(1):7080
The Novel miRNA N-72 Regulates EGF-Induced Migration of Human Amnion Mesenchymal Stem Cells by Targeting MMP2.
Li Y, Zhang D, Chen M, Wang R, Zhang T, Zhao F, Lin X, Pang X
International journal of molecular sciences 2018 May 4;19(5)
International journal of molecular sciences 2018 May 4;19(5)
Resting T cells are hypersensitive to DNA damage due to defective DNA repair pathway.
Hu Q, Xie Y, Ge Y, Nie X, Tao J, Zhao Y
Cell death & disease 2018 May 31;9(6):662
Cell death & disease 2018 May 31;9(6):662
Dietary supplementation with ketoacids protects against CKD-induced oxidative damage and mitochondrial dysfunction in skeletal muscle of 5/6 nephrectomised rats.
Wang D, Wei L, Yang Y, Liu H
Skeletal muscle 2018 May 31;8(1):18
Skeletal muscle 2018 May 31;8(1):18
Identification of Selective, Cell Active Inhibitors of Protein Arginine Methyltransferase 5 through Structure-Based Virtual Screening and Biological Assays.
Ye F, Zhang W, Ye X, Jin J, Lv Z, Luo C
Journal of chemical information and modeling 2018 May 29;58(5):1066-1073
Journal of chemical information and modeling 2018 May 29;58(5):1066-1073
MiR-29c reduces the cisplatin resistance of non-small cell lung cancer cells by negatively regulating the PI3K/Akt pathway.
Sun DM, Tang BF, Li ZX, Guo HB, Cheng JL, Song PP, Zhao X
Scientific reports 2018 May 22;8(1):8007
Scientific reports 2018 May 22;8(1):8007
Dexmedetomidine reduces ventilator-induced lung injury (VILI) by inhibiting Toll-like receptor 4 (TLR4)/nuclear factor (NF)-κB signaling pathway.
Chen H, Sun X, Yang X, Hou Y, Yu X, Wang Y, Wu J, Liu D, Wang H, Yu J, Yi W
Bosnian journal of basic medical sciences 2018 May 20;18(2):162-169
Bosnian journal of basic medical sciences 2018 May 20;18(2):162-169
Apolipoprotein C1 promotes prostate cancer cell proliferation in vitro.
Su WP, Sun LN, Yang SL, Zhao H, Zeng TY, Wu WZ, Wang D
Journal of biochemical and molecular toxicology 2018 May 2;:e22158
Journal of biochemical and molecular toxicology 2018 May 2;:e22158
Long-term exposure to low-dose Haemophilus influenzae during allergic airway disease drives a steroid-resistant neutrophilic inflammation and promotes airway remodeling.
Yang X, Wang Y, Zhao S, Wang R, Wang C
Oncotarget 2018 May 18;9(38):24898-24913
Oncotarget 2018 May 18;9(38):24898-24913
LGR5 promotes epithelial ovarian cancer proliferation, metastasis, and epithelial-mesenchymal transition through the Notch1 signaling pathway.
Liu W, Zhang J, Gan X, Shen F, Yang X, Du N, Xia D, Liu L, Qiao L, Pan J, Sun Y, Xi X
Cancer medicine 2018 May 18;
Cancer medicine 2018 May 18;
Rotenone ameliorates chronic renal injury caused by acute ischemia/reperfusion.
Zhang W, Sha Y, Wei K, Wu C, Ding D, Yang Y, Zhu C, Zhang Y, Ding G, Zhang A, Jia Z, Huang S
Oncotarget 2018 May 11;9(36):24199-24208
Oncotarget 2018 May 11;9(36):24199-24208
Single-Cell Analysis of the Impact of Host Cell Heterogeneity on Infection with Foot-and-Mouth Disease Virus.
Xin X, Wang H, Han L, Wang M, Fang H, Hao Y, Li J, Zhang H, Zheng C, Shen C
Journal of virology 2018 May 1;92(9)
Journal of virology 2018 May 1;92(9)
Autophagic degradation of caveolin-1 promotes liver sinusoidal endothelial cells defenestration.
Luo X, Wang D, Zhu X, Wang G, You Y, Ning Z, Li Y, Jin S, Huang Y, Hu Y, Chen T, Meng Y, Li X
Cell death & disease 2018 May 1;9(5):576
Cell death & disease 2018 May 1;9(5):576
KIF4A facilitates cell proliferation via induction of p21-mediated cell cycle progression and promotes metastasis in colorectal cancer.
Hou PF, Jiang T, Chen F, Shi PC, Li HQ, Bai J, Song J
Cell death & disease 2018 May 1;9(5):477
Cell death & disease 2018 May 1;9(5):477
Dkk3 dependent transcriptional regulation controls age related skeletal muscle atrophy.
Yin J, Yang L, Xie Y, Liu Y, Li S, Yang W, Xu B, Ji H, Ding L, Wang K, Li G, Chen L, Hu P
Nature communications 2018 May 1;9(1):1752
Nature communications 2018 May 1;9(1):1752
Inhibition of transient receptor potential melastatin 8 alleviates airway inflammation and remodeling in a murine model of asthma with cold air stimulus.
Liu H, Liu Q, Hua L, Pan J
Acta biochimica et biophysica Sinica 2018 May 1;50(5):499-506
Acta biochimica et biophysica Sinica 2018 May 1;50(5):499-506
Rewiring of Glutamine Metabolism Is a Bioenergetic Adaptation of Human Cells with Mitochondrial DNA Mutations.
Chen Q, Kirk K, Shurubor YI, Zhao D, Arreguin AJ, Shahi I, Valsecchi F, Primiano G, Calder EL, Carelli V, Denton TT, Beal MF, Gross SS, Manfredi G, D'Aurelio M
Cell metabolism 2018 May 1;27(5):1007-1025.e5
Cell metabolism 2018 May 1;27(5):1007-1025.e5
The Dopamine Receptor D3 Regulates Lipopolysaccharide-Induced Depressive-Like Behavior in Mice.
Wang J, Jia Y, Li G, Wang B, Zhou T, Zhu L, Chen T, Chen Y
The international journal of neuropsychopharmacology 2018 May 1;21(5):448-460
The international journal of neuropsychopharmacology 2018 May 1;21(5):448-460
Glial fibrillary acidic protein promoter determines transgene expression in satellite glial cells following intraganglionic adeno-associated virus delivery in adult rats.
Xiang H, Xu H, Fan F, Shin SM, Hogan QH, Yu H
Journal of neuroscience research 2018 Mar;96(3):436-448
Journal of neuroscience research 2018 Mar;96(3):436-448
Periostin promotes migration, proliferation, and differentiation of human periodontal ligament mesenchymal stem cells.
Wu Z, Dai W, Wang P, Zhang X, Tang Y, Liu L, Wang Q, Li M, Tang C
Connective tissue research 2018 Mar;59(2):108-119
Connective tissue research 2018 Mar;59(2):108-119
Combination Treatment with Methylene Blue and Hypothermia in Global Cerebral Ischemia.
Li L, Yang R, Li P, Lu H, Hao J, Li L, Tucker D, Zhang Q
Molecular neurobiology 2018 Mar;55(3):2042-2055
Molecular neurobiology 2018 Mar;55(3):2042-2055
Role of the hippocampal 5-HT1A receptor-mediated cAMP/PKA signalling pathway in sevoflurane-induced cognitivedysfunction in aged rats.
Qiu Y, Wang Y, Wang X, Wang C, Xia ZY
The Journal of international medical research 2018 Mar;46(3):1073-1085
The Journal of international medical research 2018 Mar;46(3):1073-1085
Baicalin protects H9c2 cardiomyocytes against hypoxia/reoxygenation-induced apoptosis and oxidative stress through activation of mitochondrial aldehyde dehydrogenase 2.
Jiang WB, Zhao W, Chen H, Wu YY, Wang Y, Fu GS, Yang XJ
Clinical and experimental pharmacology & physiology 2018 Mar;45(3):303-311
Clinical and experimental pharmacology & physiology 2018 Mar;45(3):303-311
Analysis of the oncogene BRAF mutation and the correlation of the expression of wild-type BRAF and CREB1 in endometriosis.
Lv X, Wang D, Ma Y, Long Z
International journal of molecular medicine 2018 Mar;41(3):1349-1356
International journal of molecular medicine 2018 Mar;41(3):1349-1356
Tumor-suppressive miRNA-135a inhibits breast cancer cell proliferation by targeting ELK1 and ELK3 oncogenes.
Ahmad A, Zhang W, Wu M, Tan S, Zhu T
Genes & genomics 2018 Mar;40(3):243-251
Genes & genomics 2018 Mar;40(3):243-251
miR-141 inhibits prostatic cancer cell proliferation and migration, and induces cell apoptosis via targeting of RUNX1.
Xu S, Ge J, Zhang Z, Zhou W
Oncology reports 2018 Mar;39(3):1454-1460
Oncology reports 2018 Mar;39(3):1454-1460
TAp63 is correlated with chronic inflammation in patients with newly diagnosed type 2 diabetes mellitus.
Hu X, Liu J, Sun L, Liu L, Hu Y, Yuan Y, Wu G, Wang Y, Chen J, Xu Y
Journal of diabetes and its complications 2018 Mar;32(3):335-341
Journal of diabetes and its complications 2018 Mar;32(3):335-341
Identification of a novel compound targeting the nuclear export of influenza A virus nucleoprotein.
Huang F, Chen J, Zhang J, Tan L, Lu G, Luo Y, Pan T, Liang J, Li Q, Luo B, Zhang H, Lu G
Journal of cellular and molecular medicine 2018 Mar;22(3):1826-1839
Journal of cellular and molecular medicine 2018 Mar;22(3):1826-1839
Analysis of the association of the expression of KiSS-1 in colorectal cancer tissues with the pathology and prognosis.
Huo X, Zhang L, Li T
Oncology letters 2018 Mar;15(3):3056-3060
Oncology letters 2018 Mar;15(3):3056-3060
miR-98 inhibits cell proliferation and induces cell apoptosis by targeting MAPK6 in HUVECs.
Hu C, Huang S, Wu F, Ding H
Experimental and therapeutic medicine 2018 Mar;15(3):2755-2760
Experimental and therapeutic medicine 2018 Mar;15(3):2755-2760
Type I IFN augments IL-27-dependent TRIM25 expression to inhibit HBV replication.
Tan G, Xiao Q, Song H, Ma F, Xu F, Peng D, Li N, Wang X, Niu J, Gao P, Qin FX, Cheng G
Cellular & molecular immunology 2018 Mar;15(3):272-281
Cellular & molecular immunology 2018 Mar;15(3):272-281
MAD2L2 inhibits colorectal cancer growth by promoting NCOA3 ubiquitination and degradation.
Li Y, Li L, Chen M, Yu X, Gu Z, Qiu H, Qin G, Long Q, Fu X, Liu T, Li W, Huang W, Shi D, Kang T, Luo M, Wu X, Deng W
Molecular oncology 2018 Mar;12(3):391-405
Molecular oncology 2018 Mar;12(3):391-405
Protein kinase C epsilon mediates the inhibition of angiotensin II on the slowly activating delayed-rectifier potassium current through channel phosphorylation.
Gou X, Wang W, Zou S, Qi Y, Xu Y
Journal of molecular and cellular cardiology 2018 Mar;116:165-174
Journal of molecular and cellular cardiology 2018 Mar;116:165-174
Lanthanum chloride impairs memory in rats by disturbing the glutamate-glutamine cycle and over-activating NMDA receptors.
Hu X, Yang J, Sun Y, Gao X, Zhang L, Li Y, Yu M, Liu S, Lu X, Jin C, Wu S, Cai Y
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2018 Mar;113:1-13
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2018 Mar;113:1-13
The expression of the new epididymal luminal protein of PDZ domain containing 1 is decreased in asthenozoospermia.
Liang AJ, Wang GS, Ping P, Hu SG, Lin Y, Ma Y, Duan ZZ, Wang HS, Sun F
Asian journal of andrology 2018 Mar-Apr;20(2):154-159
Asian journal of andrology 2018 Mar-Apr;20(2):154-159
MiR-134, epigenetically silenced in gliomas, could mitigate the malignant phenotype by targeting KRAS.
Wang ZL, Zhang CB, Wang Z, Meng XQ, Liu XJ, Han B, Duan CB, Cai JQ, Hao ZF, Chen MH, Jiang T, Li YL, Jiang CL, Wang HJ
Carcinogenesis 2018 Mar 8;39(3):389-396
Carcinogenesis 2018 Mar 8;39(3):389-396
SFTS phlebovirus promotes LC3-II accumulation and nonstructural protein of SFTS phlebovirus co-localizes with autophagy proteins.
Sun Y, Liu MM, Lei XY, Yu XJ
Scientific reports 2018 Mar 27;8(1):5287
Scientific reports 2018 Mar 27;8(1):5287
Inhibition of HIV early replication by the p53 and its downstream gene p21.
Shi B, Sharifi HJ, DiGrigoli S, Kinnetz M, Mellon K, Hu W, de Noronha CMC
Virology journal 2018 Mar 27;15(1):53
Virology journal 2018 Mar 27;15(1):53
Overexpression of zinc-α2-glycoprotein suppressed seizures and seizure-related neuroflammation in pentylenetetrazol-kindled rats.
Liu Y, Wang T, Liu X, Wen Y, Xu T, Yu X, Wei X, Ding X, Mo L, Yin M, Tan X, Chen L
Journal of neuroinflammation 2018 Mar 22;15(1):92
Journal of neuroinflammation 2018 Mar 22;15(1):92
The transcriptional profiles and functional implications of long non-coding RNAs in the unfolded protein response.
Quan H, Fan Q, Li C, Wang YY, Wang L
Scientific reports 2018 Mar 21;8(1):4981
Scientific reports 2018 Mar 21;8(1):4981
Regulation by FSH of the dynamic expression of retinol-binding protein 4 in the mouse ovary.
Jiang Y, Zhao Y, Chen S, Chen L, Li C, Zhou X
Reproductive biology and endocrinology : RB&E 2018 Mar 20;16(1):25
Reproductive biology and endocrinology : RB&E 2018 Mar 20;16(1):25
Transmembrane E3 ligase RNF183 mediates ER stress-induced apoptosis by degrading Bcl-xL.
Wu Y, Li X, Jia J, Zhang Y, Li J, Zhu Z, Wang H, Tang J, Hu J
Proceedings of the National Academy of Sciences of the United States of America 2018 Mar 20;115(12):E2762-E2771
Proceedings of the National Academy of Sciences of the United States of America 2018 Mar 20;115(12):E2762-E2771
Pin1 mediates Aβ42-induced dendritic spine loss.
Stallings NR, O'Neal MA, Hu J, Kavalali ET, Bezprozvanny I, Malter JS
Science signaling 2018 Mar 20;11(522)
Science signaling 2018 Mar 20;11(522)
PIWIL1/piRNA-DQ593109 Regulates the Permeability of the Blood-Tumor Barrier via the MEG3/miR-330-5p/RUNX3 Axis.
Shen S, Yu H, Liu X, Liu Y, Zheng J, Wang P, Gong W, Chen J, Zhao L, Xue Y
Molecular therapy. Nucleic acids 2018 Mar 2;10:412-425
Molecular therapy. Nucleic acids 2018 Mar 2;10:412-425
circ-SHKBP1 Regulates the Angiogenesis of U87 Glioma-Exposed Endothelial Cells through miR-544a/FOXP1 and miR-379/FOXP2 Pathways.
He Q, Zhao L, Liu Y, Liu X, Zheng J, Yu H, Cai H, Ma J, Liu L, Wang P, Li Z, Xue Y
Molecular therapy. Nucleic acids 2018 Mar 2;10:331-348
Molecular therapy. Nucleic acids 2018 Mar 2;10:331-348
Zc3h13 Regulates Nuclear RNA m6A Methylation and Mouse Embryonic Stem Cell Self-Renewal.
Wen J, Lv R, Ma H, Shen H, He C, Wang J, Jiao F, Liu H, Yang P, Tan L, Lan F, Shi YG, He C, Shi Y, Diao J
Molecular cell 2018 Mar 15;69(6):1028-1038.e6
Molecular cell 2018 Mar 15;69(6):1028-1038.e6
In vitro study of FUZ as a novel potential therapeutic target in non-small-cell lung cancer.
He M, Li K, Yu C, Lv B, Zhao N, Deng J, Cao L, Huang H, Yin A, Shi T, Wang L
Life sciences 2018 Mar 15;197:91-100
Life sciences 2018 Mar 15;197:91-100
Cigarette smoke stimulates the stemness of renal cancer stem cells via Sonic Hedgehog pathway.
Qian W, Kong X, Zhang T, Wang D, Song J, Li Y, Li X, Geng H, Min J, Kong Q, Liu J, Liu Z, Wang D, Zhang Z, Yu D, Zhong C
Oncogenesis 2018 Mar 13;7(3):24
Oncogenesis 2018 Mar 13;7(3):24
Structural Basis for the Inhibition of Host Gene Expression by Porcine Epidemic Diarrhea Virus nsp1.
Shen Z, Ye G, Deng F, Wang G, Cui M, Fang L, Xiao S, Fu ZF, Peng G
Journal of virology 2018 Mar 1;92(5)
Journal of virology 2018 Mar 1;92(5)
LncRNA UCA1 attenuates autophagy-dependent cell death through blocking autophagic flux under arsenic stress.
Gao M, Li C, Xu M, Liu Y, Liu S
Toxicology letters 2018 Mar 1;284:195-204
Toxicology letters 2018 Mar 1;284:195-204
Cell division cycle 7 is a potential therapeutic target in oral squamous cell carcinoma and is regulated by E2F1.
Jin S, Ma H, Yang W, Ju H, Wang L, Zhang Z
Journal of molecular medicine (Berlin, Germany) 2018 Jun;96(6):513-525
Journal of molecular medicine (Berlin, Germany) 2018 Jun;96(6):513-525
Propranolol prevents liver cirrhosis by inhibiting hepatic stellate cell activation mediated by the PDGFR/Akt pathway.
Ding Q, Li Z, Liu B, Ling L, Tian X, Zhang C
Human pathology 2018 Jun;76:37-46
Human pathology 2018 Jun;76:37-46
Setd7 and its contribution to Boron-induced bone regeneration in Boron-mesoporous bioactive glass scaffolds.
Yin C, Jia X, Miron RJ, Long Q, Xu H, Wei Y, Wu M, Zhang Y, Li Z
Acta biomaterialia 2018 Jun;73:522-530
Acta biomaterialia 2018 Jun;73:522-530
Clinical significance of combined detection of interleukin-6 and tumour markers in lung cancer.
Tang H, Bai Y, Shen W, Wei Y, Xu M, Zhou X, Zhao J
Autoimmunity 2018 Jun;51(4):191-198
Autoimmunity 2018 Jun;51(4):191-198
Oestrogen receptor β5 and epidermal growth factor receptor synergistically promote lung cancer progression.
Bai Y, Shen W, Zhang L, Yang Z, Xiong L, Tang H, Zhao J
Autoimmunity 2018 Jun;51(4):157-165
Autoimmunity 2018 Jun;51(4):157-165
Mutant KRAS promotes liver metastasis of colorectal cancer, in part, by upregulating the MEK-Sp1-DNMT1-miR-137-YB-1-IGF-IR signaling pathway.
Chu PC, Lin PC, Wu HY, Lin KT, Wu C, Bekaii-Saab T, Lin YJ, Lee CT, Lee JC, Chen CS
Oncogene 2018 Jun;37(25):3440-3455
Oncogene 2018 Jun;37(25):3440-3455
Sequestosome 1 protects esophageal squamous carcinoma cells from apoptosis via stabilizing SKP2 under serum starvation condition.
Shi C, Pan BQ, Shi F, Xie ZH, Jiang YY, Shang L, Zhang Y, Xu X, Cai Y, Hao JJ, Wang MR
Oncogene 2018 Jun;37(24):3260-3274
Oncogene 2018 Jun;37(24):3260-3274
Abberent expression of NOR1 protein in tumor associated macrophages contributes to the development of DEN-induced hepatocellular carcinoma.
Chen S, Zheng P, Wang W, Yi M, Chen P, Cai J, Li J, Peng Q, Ban Y, Zhou Y, Zeng Z, Li X, Xiong W, Li G, Xiang B
Journal of cellular physiology 2018 Jun;233(6):5002-5013
Journal of cellular physiology 2018 Jun;233(6):5002-5013
S1PR3 is essential for phosphorylated fingolimod to protect astrocytes against oxygen-glucose deprivation-induced neuroinflammation via inhibiting TLR2/4-NFκB signalling.
Dong YF, Guo RB, Ji J, Cao LL, Zhang L, Chen ZZ, Huang JY, Wu J, Lu J, Sun XL
Journal of cellular and molecular medicine 2018 Jun;22(6):3159-3166
Journal of cellular and molecular medicine 2018 Jun;22(6):3159-3166
Correlation between autophagy levels in peripheral blood mononuclear cells and clinical parameters in patients with chronic obstructive pulmonary disease.
Wu Y, Xu B, He X, Wu B, Li Y, Yu G, Tan C, Wang H
Molecular medicine reports 2018 Jun;17(6):8003-8009
Molecular medicine reports 2018 Jun;17(6):8003-8009
Osteogenesis potential of different titania nanotubes in oxidative stress microenvironment.
Yu Y, Shen X, Luo Z, Hu Y, Li M, Ma P, Ran Q, Dai L, He Y, Cai K
Biomaterials 2018 Jun;167:44-57
Biomaterials 2018 Jun;167:44-57
Protective effect of dioscin against doxorubicin-induced cardiotoxicity via adjusting microRNA-140-5p-mediated myocardial oxidative stress.
Zhao L, Tao X, Qi Y, Xu L, Yin L, Peng J
Redox biology 2018 Jun;16:189-198
Redox biology 2018 Jun;16:189-198
Downregulation of FOXP2 promotes breast cancer migration and invasion through TGFβ/SMAD signaling pathway.
Chen MT, Sun HF, Li LD, Zhao Y, Yang LP, Gao SP, Jin W
Oncology letters 2018 Jun;15(6):8582-8588
Oncology letters 2018 Jun;15(6):8582-8588
Excessive endoplasmic reticulum stress and decreased neuroplasticity-associated proteins in prefrontal cortex of obese rats and the regulatory effects of aerobic exercise.
Li F, Liu BB, Cai M, Li JJ, Lou SJ
Brain research bulletin 2018 Jun;140:52-59
Brain research bulletin 2018 Jun;140:52-59
Cognitive-enhancing effect of polysaccharides from Flammulina velutipes on Alzheimer's disease by compatibilizing with ginsenosides.
Zhang Y, Li H, Yang X, Jin G, Zhang Y
International journal of biological macromolecules 2018 Jun;112:788-795
International journal of biological macromolecules 2018 Jun;112:788-795
Krüppel-like factor 4 promotes c-Met amplification-mediated gefitinib resistance in non-small-cell lung cancer.
Feng W, Xie Q, Liu S, Ji Y, Li C, Wang C, Jin L
Cancer science 2018 Jun;109(6):1775-1786
Cancer science 2018 Jun;109(6):1775-1786
Effects of cholecalciferol cholesterol emulsion on renal fibrosis and aquaporin 2 and 4 in mice with unilateral ureteral obstruction.
Liu N, Zhang Y, Su H, Wang J, Liu Z, Kong J
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Jun;102:633-638
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Jun;102:633-638
The natural compound GL22, isolated from Ganoderma mushrooms, suppresses tumor growth by altering lipid metabolism and triggering cell death.
Liu G, Wang K, Kuang S, Cao R, Bao L, Liu R, Liu H, Sun C
Cell death & disease 2018 Jun 7;9(6):689
Cell death & disease 2018 Jun 7;9(6):689
Metformin ameliorates TGF-β1-induced osteoblastic differentiation of human aortic valve interstitial cells by inhibiting β-catenin signaling.
Liu F, Chu C, Wei Q, Shi J, Li H, Dong N
Biochemical and biophysical research communications 2018 Jun 7;500(3):710-716
Biochemical and biophysical research communications 2018 Jun 7;500(3):710-716
HEV ORF3 downregulates TLR7 to inhibit the generation of type I interferon via impairment of multiple signaling pathways.
Lei Q, Li L, Zhang S, Li T, Zhang X, Ding X, Qin B
Scientific reports 2018 Jun 5;8(1):8585
Scientific reports 2018 Jun 5;8(1):8585
Integrin αvβ3-associated DAAM1 is essential for collagen-induced invadopodia extension and cell haptotaxis in breast cancer cells.
Yan T, Zhang A, Shi F, Chang F, Mei J, Liu Y, Zhu Y
The Journal of biological chemistry 2018 Jun 29;293(26):10172-10185
The Journal of biological chemistry 2018 Jun 29;293(26):10172-10185
Traditional Chinese medication Tongxinluo attenuates apoptosis in ox-LDL-stimulated macrophages by enhancing Beclin-1-induced autophagy.
Chen Y, Li M, Zhang Y, Di M, Chen W, Liu X, Yu F, Wang H, Zhen X, Zhang M
Biochemical and biophysical research communications 2018 Jun 22;501(2):336-342
Biochemical and biophysical research communications 2018 Jun 22;501(2):336-342
Carbon monoxide-releasing molecule-3 protects against ischemic stroke by suppressing neuroinflammation and alleviating blood-brain barrier disruption.
Wang J, Zhang D, Fu X, Yu L, Lu Z, Gao Y, Liu X, Man J, Li S, Li N, Chen X, Hong M, Yang Q, Wang J
Journal of neuroinflammation 2018 Jun 21;15(1):188
Journal of neuroinflammation 2018 Jun 21;15(1):188
4EHP-independent repression of endogenous mRNAs by the RNA-binding protein GIGYF2.
Amaya Ramirez CC, Hubbe P, Mandel N, Béthune J
Nucleic acids research 2018 Jun 20;46(11):5792-5808
Nucleic acids research 2018 Jun 20;46(11):5792-5808
Deer thymosin beta 10 functions as a novel factor for angiogenesis and chondrogenesis during antler growth and regeneration.
Zhang W, Chu W, Liu Q, Coates D, Shang Y, Li C
Stem cell research & therapy 2018 Jun 19;9(1):166
Stem cell research & therapy 2018 Jun 19;9(1):166
Oxidative stress-mediated autophagic cell death participates in the neurotoxic effect on SH-SY5Y cells induced by excessive iodide.
Liu H, Wang L, Zeng Q, Zhao L, Cui Y, Hou C, Zhang B, Zhang Z, Zhang S, Chen X, Wang A
Environmental toxicology 2018 Jun 19;
Environmental toxicology 2018 Jun 19;
SPG6 supports development of acute myeloid leukemia by regulating BMPR2-Smad-Bcl-2/Bcl-xl signaling.
Chen J, Li C, Zhan R, Yin Y
Biochemical and biophysical research communications 2018 Jun 18;501(1):220-225
Biochemical and biophysical research communications 2018 Jun 18;501(1):220-225
PHF5A Epigenetically Inhibits Apoptosis to Promote Breast Cancer Progression.
Zheng YZ, Xue MZ, Shen HJ, Li XG, Ma D, Gong Y, Liu YR, Qiao F, Xie HY, Lian B, Sun WL, Zhao HY, Yao L, Zuo WJ, Li DQ, Wang P, Hu X, Shao ZM
Cancer research 2018 Jun 15;78(12):3190-3206
Cancer research 2018 Jun 15;78(12):3190-3206
RBM4 Modulates Radial Migration via Alternative Splicing of Dab1 during Cortex Development.
D D, Hung KY, Tarn WY
Molecular and cellular biology 2018 Jun 15;38(12)
Molecular and cellular biology 2018 Jun 15;38(12)
Reversal of reserpine-induced depression and cognitive disorder in zebrafish by sertraline and Traditional Chinese Medicine (TCM).
Zhang S, Liu X, Sun M, Zhang Q, Li T, Li X, Xu J, Zhao X, Chen D, Feng X
Behavioral and brain functions : BBF 2018 Jun 14;14(1):13
Behavioral and brain functions : BBF 2018 Jun 14;14(1):13
Exosomes released by hepatocarcinoma cells endow adipocytes with tumor-promoting properties.
Wang S, Xu M, Li X, Su X, Xiao X, Keating A, Zhao RC
Journal of hematology & oncology 2018 Jun 14;11(1):82
Journal of hematology & oncology 2018 Jun 14;11(1):82
Downregulation of HS6ST2 by miR-23b-3p enhances matrix degradation through p38 MAPK pathway in osteoarthritis.
Guo Y, Min Z, Jiang C, Wang W, Yan J, Xu P, Xu K, Xu J, Sun M, Zhao Y, Hussain S, Zhang R, Wang Q, Han Y, Zhang F, Zhu W, Li D, Meng L, Sun J, Lu S
Cell death & disease 2018 Jun 13;9(6):699
Cell death & disease 2018 Jun 13;9(6):699
BAI1 Suppresses Medulloblastoma Formation by Protecting p53 from Mdm2-Mediated Degradation.
Zhu D, Osuka S, Zhang Z, Reichert ZR, Yang L, Kanemura Y, Jiang Y, You S, Zhang H, Devi NS, Bhattacharya D, Takano S, Gillespie GY, Macdonald T, Tan C, Nishikawa R, Nelson WG, Olson JJ, Van Meir EG
Cancer cell 2018 Jun 11;33(6):1004-1016.e5
Cancer cell 2018 Jun 11;33(6):1004-1016.e5
miR-675 promotes odontogenic differentiation of human dental pulp cells by epigenetic regulation of DLX3.
Zeng L, Zhao N, Li F, Han D, Liu Y, Liu H, Sun S, Wang Y, Feng H
Experimental cell research 2018 Jun 1;367(1):104-111
Experimental cell research 2018 Jun 1;367(1):104-111
Acetylation of oxidized base repair-initiating NEIL1 DNA glycosylase required for chromatin-bound repair complex formation in the human genome increases cellular resistance to oxidative stress.
Sengupta S, Yang C, Hegde ML, Hegde PM, Mitra J, Pandey A, Dutta A, Datarwala AT, Bhakat KK, Mitra S
DNA repair 2018 Jun - Jul;66-67:1-10
DNA repair 2018 Jun - Jul;66-67:1-10
HBeAg induces the expression of macrophage miR-155 to accelerate liver injury via promoting production of inflammatory cytokines.
Wang W, Bian H, Li F, Li X, Zhang D, Sun S, Song S, Zhu Q, Ren W, Qin C, Qi J
Cellular and molecular life sciences : CMLS 2018 Jul;75(14):2627-2641
Cellular and molecular life sciences : CMLS 2018 Jul;75(14):2627-2641
Furin promotes dendritic morphogenesis and learning and memory in transgenic mice.
Zhu B, Zhao L, Luo D, Xu D, Tan T, Dong Z, Tang Y, Min Z, Deng X, Sun F, Yan Z, Chen G
Cellular and molecular life sciences : CMLS 2018 Jul;75(13):2473-2488
Cellular and molecular life sciences : CMLS 2018 Jul;75(13):2473-2488
Farnesoid X receptor signaling activates the hepatic X-box binding protein 1 pathway in vitro and in mice.
Liu X, Guo GL, Kong B, Hilburn DB, Hubchak SC, Park S, LeCuyer B, Hsieh A, Wang L, Fang D, Green RM
Hepatology (Baltimore, Md.) 2018 Jul;68(1):304-316
Hepatology (Baltimore, Md.) 2018 Jul;68(1):304-316
Anti-fibrogenic Potential of Mesenchymal Stromal Cells in Treating Fibrosis in Crohn's Disease.
Lian L, Huang Q, Zhang L, Qin H, He X, He X, Ke J, Xie M, Lan P
Digestive diseases and sciences 2018 Jul;63(7):1821-1834
Digestive diseases and sciences 2018 Jul;63(7):1821-1834
Glycyrrhizin ameliorates atopic dermatitis-like symptoms through inhibition of HMGB1.
Wang Y, Zhang Y, Peng G, Han X
International immunopharmacology 2018 Jul;60:9-17
International immunopharmacology 2018 Jul;60:9-17
LncRNA MT1DP Aggravates Cadmium-Induced Oxidative Stress by Repressing the Function of Nrf2 and is Dependent on Interaction with miR-365.
Gao M, Li C, Xu M, Liu Y, Cong M, Liu S
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2018 Jul;5(7):1800087
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2018 Jul;5(7):1800087
BCL11A Down-Regulation Induces γ-Globin in Human β-Thalassemia Major Erythroid Cells.
Li J, Lai Y, Shi L
Hemoglobin 2018 Jul;42(4):225-230
Hemoglobin 2018 Jul;42(4):225-230
Programmed death ligand 1 promotes lymph node metastasis and glucose metabolism in cervical cancer by activating integrin β4/SNAI1/SIRT3 signaling pathway.
Wang S, Li J, Xie J, Liu F, Duan Y, Wu Y, Huang S, He X, Wang Z, Wu X
Oncogene 2018 Jul;37(30):4164-4180
Oncogene 2018 Jul;37(30):4164-4180
Estrogen-related receptor alpha is involved in Alzheimer's disease-like pathology.
Tang Y, Min Z, Xiang XJ, Liu L, Ma YL, Zhu BL, Song L, Tang J, Deng XJ, Yan Z, Chen GJ
Experimental neurology 2018 Jul;305:89-96
Experimental neurology 2018 Jul;305:89-96
The endosomal recycling of FgSnc1 by FgSnx41-FgSnx4 heterodimer is essential for polarized growth and pathogenicity in Fusarium graminearum.
Zheng W, Lin Y, Fang W, Zhao X, Lou Y, Wang G, Zheng H, Liang Q, Abubakar YS, Olsson S, Zhou J, Wang Z
The New phytologist 2018 Jul;219(2):654-671
The New phytologist 2018 Jul;219(2):654-671
Inhibition of Mitochondrial Fission Preserves Photoreceptors after Retinal Detachment.
She X, Lu X, Li T, Sun J, Liang J, Zhai Y, Yang S, Gu Q, Wei F, Zhu H, Wang F, Luo X, Sun X
The American journal of pathology 2018 Jul;188(7):1713-1722
The American journal of pathology 2018 Jul;188(7):1713-1722
Increased oxidative stress mediates the antitumor effect of PARP inhibition in ovarian cancer.
Hou D, Liu Z, Xu X, Liu Q, Zhang X, Kong B, Wei JJ, Gong Y, Shao C
Redox biology 2018 Jul;17:99-111
Redox biology 2018 Jul;17:99-111
Sulforaphane attenuates microglia-mediated neuronal necroptosis through down-regulation of MAPK/NF-κB signaling pathways in LPS-activated BV-2 microglia.
Qin S, Yang C, Huang W, Du S, Mai H, Xiao J, Lü T
Pharmacological research 2018 Jul;133:218-235
Pharmacological research 2018 Jul;133:218-235
Temporary inhibition of the plasminogen activator inhibits periosteal chondrogenesis and promotes periosteal osteogenesis during appendicular bone fracture healing.
Bravo D, Josephson AM, Bradaschia-Correa V, Wong MZ, Yim NL, Neibart SS, Lee SN, Huo J, Coughlin T, Mizrahi MM, Leucht P
Bone 2018 Jul;112:97-106
Bone 2018 Jul;112:97-106
BET bromodomain inhibitor JQ1 preferentially suppresses EBV-positive nasopharyngeal carcinoma cells partially through repressing c-Myc.
Li N, Yang L, Qi XK, Lin YX, Xie X, He GP, Feng QS, Liu LR, Xie X, Zeng YX, Feng L
Cell death & disease 2018 Jul 9;9(7):761
Cell death & disease 2018 Jul 9;9(7):761
SET1A-Mediated Mono-Methylation at K342 Regulates YAP Activation by Blocking Its Nuclear Export and Promotes Tumorigenesis.
Fang L, Teng H, Wang Y, Liao G, Weng L, Li Y, Wang X, Jin J, Jiao C, Chen L, Peng X, Chen J, Yang Y, Fang H, Han D, Li C, Jin X, Zhang S, Liu Z, Liu M, Wei Q, Liao L, Ge X, Zhao B, Zhou D, Qin HL, Zhou J, Wang P
Cancer cell 2018 Jul 9;34(1):103-118.e9
Cancer cell 2018 Jul 9;34(1):103-118.e9
Naringenin exhibits the protective effect on cardiac hypertrophy via EETs-PPARs activation in streptozocin-induced diabetic mice.
Zhang J, Qiu H, Huang J, Ding S, Huang B, Wu Q, Jiang Q
Biochemical and biophysical research communications 2018 Jul 7;502(1):55-61
Biochemical and biophysical research communications 2018 Jul 7;502(1):55-61
The exon 19-deleted EGFR undergoes ubiquitylation-mediated endocytic degradation via dynamin activity-dependent and -independent mechanisms.
Wang T, Zhang J, Wang S, Sun X, Wang D, Gao Y, Zhang Y, Xu L, Wu Y, Wu Y, Liu F, Liu X, Liu S, Zhang Y, Wang Y, Zou L, Liu H
Cell communication and signaling : CCS 2018 Jul 5;16(1):40
Cell communication and signaling : CCS 2018 Jul 5;16(1):40
Ketamine differentially restores diverse alterations of neuroligins in brain regions in a rat model of neuropathic pain-induced depression.
Pan W, Zhang GF, Li HH, Ji MH, Zhou ZQ, Li KY, Yang JJ
Neuroreport 2018 Jul 4;29(10):863-869
Neuroreport 2018 Jul 4;29(10):863-869
Tristetraprolin Overexpression in Gastric Cancer Cells Suppresses PD-L1 Expression and Inhibits Tumor Progression by Enhancing Antitumor Immunity.
Guo J, Qu H, Shan T, Chen Y, Chen Y, Xia J
Molecules and cells 2018 Jul 31;41(7):653-664
Molecules and cells 2018 Jul 31;41(7):653-664
Circular RNA IARS (circ-IARS) secreted by pancreatic cancer cells and located within exosomes regulates endothelial monolayer permeability to promote tumor metastasis.
Li J, Li Z, Jiang P, Peng M, Zhang X, Chen K, Liu H, Bi H, Liu X, Li X
Journal of experimental & clinical cancer research : CR 2018 Jul 31;37(1):177
Journal of experimental & clinical cancer research : CR 2018 Jul 31;37(1):177
PEI-Coated Fe₃O₄ Nanoparticles Enable Efficient Delivery of Therapeutic siRNA Targeting REST into Glioblastoma Cells.
Wang R, Degirmenci V, Xin H, Li Y, Wang L, Chen J, Hu X, Zhang D
International journal of molecular sciences 2018 Jul 31;19(8)
International journal of molecular sciences 2018 Jul 31;19(8)
Imbalanced LIMK1 and LIMK2 expression leads to human colorectal cancer progression and metastasis via promoting β-catenin nuclear translocation.
Zhang Y, Li A, Shi J, Fang Y, Gu C, Cai J, Lin C, Zhao L, Liu S
Cell death & disease 2018 Jul 3;9(7):749
Cell death & disease 2018 Jul 3;9(7):749
17β-estradiol upregulates IL6 expression through the ERβ pathway to promote lung adenocarcinoma progression.
Huang Q, Zhang Z, Liao Y, Liu C, Fan S, Wei X, Ai B, Xiong J
Journal of experimental & clinical cancer research : CR 2018 Jul 3;37(1):133
Journal of experimental & clinical cancer research : CR 2018 Jul 3;37(1):133
3-O-acetyl-11-keto-β-boswellic acid exerts anti-tumor effects in glioblastoma by arresting cell cycle at G2/M phase.
Li W, Liu J, Fu W, Zheng X, Ren L, Liu S, Wang J, Ji T, Du G
Journal of experimental & clinical cancer research : CR 2018 Jul 3;37(1):132
Journal of experimental & clinical cancer research : CR 2018 Jul 3;37(1):132
ZDHHC8 critically regulates seizure susceptibility in epilepsy.
Yang Q, Zheng F, Hu Y, Yang Y, Li Y, Chen G, Wang W, He M, Zhou R, Ma Y, Xu D, Tian X, Gao X, Wang Q, Wang X
Cell death & disease 2018 Jul 23;9(8):795
Cell death & disease 2018 Jul 23;9(8):795
FoxM1 repression during human aging leads to mitotic decline and aneuploidy-driven full senescence.
Macedo JC, Vaz S, Bakker B, Ribeiro R, Bakker PL, Escandell JM, Ferreira MG, Medema R, Foijer F, Logarinho E
Nature communications 2018 Jul 19;9(1):2834
Nature communications 2018 Jul 19;9(1):2834
Long non-coding RNA PVT1 promotes malignancy in human endometrial carcinoma cells through negative regulation of miR-195-5p.
Kong F, Ma J, Yang H, Yang D, Wang C, Ma X
Biochimica et biophysica acta. Molecular cell research 2018 Jul 19;
Biochimica et biophysica acta. Molecular cell research 2018 Jul 19;
Comparison of the effects of selenomethionine and selenium-enriched yeast in the triple-transgenic mouse model of Alzheimer's disease.
Zhang ZH, Wu QY, Chen C, Zheng R, Chen Y, Ni JZ, Song GL
Food & function 2018 Jul 17;9(7):3965-3973
Food & function 2018 Jul 17;9(7):3965-3973
Unique BIR domain sets determine inhibitor of apoptosis protein-driven cell death and NOD2 complex signal specificity.
Chirieleison SM, Rathkey JK, Abbott DW
Science signaling 2018 Jul 17;11(539)
Science signaling 2018 Jul 17;11(539)
Aspirin is Involved in the Cell Cycle Arrest, Apoptosis, Cell Migration, and Invasion of Oral Squamous Cell Carcinoma.
Zhang X, Feng H, Li Z, Guo J, Li M
International journal of molecular sciences 2018 Jul 12;19(7)
International journal of molecular sciences 2018 Jul 12;19(7)
TNFRSF19 Inhibits TGFβ Signaling through Interaction with TGFβ Receptor Type I to Promote Tumorigenesis.
Deng C, Lin YX, Qi XK, He GP, Zhang Y, Zhang HJ, Xu M, Feng QS, Bei JX, Zeng YX, Feng L
Cancer research 2018 Jul 1;78(13):3469-3483
Cancer research 2018 Jul 1;78(13):3469-3483
Protective effect of dioscin against thioacetamide-induced acute liver injury via FXR/AMPK signaling pathway in vivo.
Zheng L, Yin L, Xu L, Qi Y, Li H, Xu Y, Han X, Liu K, Peng J
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Jan;97:481-488
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Jan;97:481-488
Stachydrine ameliorates carbon tetrachloride-induced hepatic fibrosis by inhibiting inflammation, oxidative stress and regulating MMPs/TIMPs system in rats.
Zhang J, Yang A, Wu Y, Guan W, Xiong B, Peng X, Wei X, Chen C, Liu Z
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Jan;97:1586-1594
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Jan;97:1586-1594
β-Arrestin-1 deficiency ameliorates renal interstitial fibrosis by blocking Wnt1/β-catenin signaling in mice.
Xu H, Li Q, Liu J, Zhu J, Li L, Wang Z, Zhang Y, Sun Y, Sun J, Wang R, Yi F
Journal of molecular medicine (Berlin, Germany) 2018 Jan;96(1):97-109
Journal of molecular medicine (Berlin, Germany) 2018 Jan;96(1):97-109
Limb remote ischemia per-conditioning protects the heart against ischemia-reperfusion injury through the opioid system in rats.
Zhang L, Guo H, Yuan F, Hong ZC, Tian YM, Zhang XJ, Zhang Y
Canadian journal of physiology and pharmacology 2018 Jan;96(1):68-75
Canadian journal of physiology and pharmacology 2018 Jan;96(1):68-75
Propofol attenuates myocardial ischemia reperfusion injury partly through inhibition of resident cardiac mast cell activation.
Yu X, Sun X, Zhao M, Hou Y, Li J, Yu J, Hou Y
International immunopharmacology 2018 Jan;54:267-274
International immunopharmacology 2018 Jan;54:267-274
Vimentin is a crucial target for anti-metastasis therapy of nasopharyngeal carcinoma.
Wang W, Yi M, Zhang R, Li J, Chen S, Cai J, Zeng Z, Li X, Xiong W, Wang L, Li G, Xiang B
Molecular and cellular biochemistry 2018 Jan;438(1-2):47-57
Molecular and cellular biochemistry 2018 Jan;438(1-2):47-57
Knockdown of eukaryotic translation initiation factor 3 subunit D (eIF3D) inhibits proliferation of acute myeloid leukemia cells.
Liu GZ, Liu JZ, Li XQ, Zhang L, Li SJ, Xiao TW, Wang JX, Li GY, Liu Y
Molecular and cellular biochemistry 2018 Jan;438(1-2):191-198
Molecular and cellular biochemistry 2018 Jan;438(1-2):191-198
Proteasome inhibitor bortezomib is a novel therapeutic agent for focal radiation-induced osteoporosis.
Chandra A, Wang L, Young T, Zhong L, Tseng WJ, Levine MA, Cengel K, Liu XS, Zhang Y, Pignolo RJ, Qin L
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2018 Jan;32(1):52-62
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2018 Jan;32(1):52-62
Localization of endogenous amyloid-β to the coeruleo-cortical pathway: consequences of noradrenergic depletion.
Ross JA, Reyes BAS, Thomas SA, Van Bockstaele EJ
Brain structure & function 2018 Jan;223(1):267-284
Brain structure & function 2018 Jan;223(1):267-284
Down-regulation of miR-10a-5p in synoviocytes contributes to TBX5-controlled joint inflammation.
Hussain N, Zhu W, Jiang C, Xu J, Wu X, Geng M, Hussain S, Cai Y, Xu K, Xu P, Han Y, Sun J, Meng L, Lu S
Journal of cellular and molecular medicine 2018 Jan;22(1):241-250
Journal of cellular and molecular medicine 2018 Jan;22(1):241-250
IgE induces hypotension in asthma mice by down-regulating vascular NCX1 expression through activating MiR-212-5p.
Zhao H, Song X, Yan L, Ren M, Cui X, Li Y, Gao R, Zhang W, Liu M, Liu B, Hu Y, Wang J
Biochimica et biophysica acta. Molecular basis of disease 2018 Jan;1864(1):189-196
Biochimica et biophysica acta. Molecular basis of disease 2018 Jan;1864(1):189-196
Cell Cycle-Dependent Tumor Engraftment and Migration Are Enabled by Aurora-A.
Chu TLH, Connell M, Zhou L, He Z, Won J, Chen H, Rahavi SMR, Mohan P, Nemirovsky O, Fotovati A, Pujana MA, Reid GSD, Nielsen TO, Pante N, Maxwell CA
Molecular cancer research : MCR 2018 Jan;16(1):16-31
Molecular cancer research : MCR 2018 Jan;16(1):16-31
Sphingomyelin synthase 2 overexpression promotes cisplatin-induced apoptosis of HepG2 cells.
Luo S, Pan Z, Liu S, Yuan S, Yan N
Oncology letters 2018 Jan;15(1):483-488
Oncology letters 2018 Jan;15(1):483-488
PTEN-L promotes type I interferon responses and antiviral immunity.
Cao Y, Wang H, Yang L, Zhang Z, Li C, Yuan X, Bu L, Chen L, Chen Y, Li CM, Guo D
Cellular & molecular immunology 2018 Jan;15(1):48-57
Cellular & molecular immunology 2018 Jan;15(1):48-57
20-HETE regulated PSMB5 expression via TGF-β/Smad signaling pathway.
Lai G, Sun R, Wu J, Zhang B, Zhao Y
Prostaglandins & other lipid mediators 2018 Jan;134:123-130
Prostaglandins & other lipid mediators 2018 Jan;134:123-130
Icariin, a flavonoid with anti-cancer effects, alleviated paclitaxel-induced neuropathic pain in a SIRT1-dependent manner.
Gui Y, Zhang J, Chen L, Duan S, Tang J, Xu W, Li A
Molecular pain 2018 Jan-Dec;14:1744806918768970
Molecular pain 2018 Jan-Dec;14:1744806918768970
Downregulation of N6-methyladenosine binding YTHDF2 protein mediated by miR-493-3p suppresses prostate cancer by elevating N6-methyladenosine levels.
Li J, Meng S, Xu M, Wang S, He L, Xu X, Wang X, Xie L
Oncotarget 2018 Jan 9;9(3):3752-3764
Oncotarget 2018 Jan 9;9(3):3752-3764
Inhibition of insulin resistance by PGE1 via autophagy-dependent FGF21 pathway in diabetic nephropathy.
Wei W, An XR, Jin SJ, Li XX, Xu M
Scientific reports 2018 Jan 8;8(1):9
Scientific reports 2018 Jan 8;8(1):9
Genomic and Epigenomic Profiling of High-Risk Intestinal Metaplasia Reveals Molecular Determinants of Progression to Gastric Cancer.
Huang KK, Ramnarayanan K, Zhu F, Srivastava S, Xu C, Tan ALK, Lee M, Tay S, Das K, Xing M, Fatehullah A, Alkaff SMF, Lim TKH, Lee J, Ho KY, Rozen SG, Teh BT, Barker N, Chia CK, Khor C, Ooi CJ, Fock KM, So J, Lim WC, Ling KL, Ang TL, Wong A, Rao J, Rajnakova A, Lim LG, Yap WM, Teh M, Yeoh KG, Tan P
Cancer cell 2018 Jan 8;33(1):137-150.e5
Cancer cell 2018 Jan 8;33(1):137-150.e5
Neutrophil extracellular traps contribute to the pathogenesis of acid-aspiration-induced ALI/ARDS.
Li H, Zhou X, Tan H, Hu Y, Zhang L, Liu S, Dai M, Li Y, Li Q, Mao Z, Pan P, Su X, Hu C
Oncotarget 2018 Jan 5;9(2):1772-1784
Oncotarget 2018 Jan 5;9(2):1772-1784
Protective Effects of Leukemia Inhibitory Factor on Retinal Vasculature and Cells in Streptozotocin-induced Diabetic Mice.
Yang XF, Huang YX, Lan M, Zhang TR, Zhou J
Chinese medical journal 2018 Jan 5;131(1):75-81
Chinese medical journal 2018 Jan 5;131(1):75-81
Antidiabetic activities of entagenic acid in type 2 diabetic db/db mice and L6 myotubes via AMPK/GLUT4 pathway.
Xiong H, Zhang S, Zhao Z, Zhao P, Chen L, Mei Z
Journal of ethnopharmacology 2018 Jan 30;211:366-374
Journal of ethnopharmacology 2018 Jan 30;211:366-374
LncRNA LOC730101 promotes osteosarcoma cell survival under energy stress.
Cheng G, Li B, Sun X, Cao Z, Zhang G, Zhao Z, Zhao Y, Yu Q, Liu W
Biochemical and biophysical research communications 2018 Jan 29;496(1):1-6
Biochemical and biophysical research communications 2018 Jan 29;496(1):1-6
Hydrogen-water ameliorates radiation-induced gastrointestinal toxicity via MyD88's effects on the gut microbiota.
Xiao HW, Li Y, Luo D, Dong JL, Zhou LX, Zhao SY, Zheng QS, Wang HC, Cui M, Fan SJ
Experimental & molecular medicine 2018 Jan 26;50(1):e433
Experimental & molecular medicine 2018 Jan 26;50(1):e433
Gentiopicroside ameliorates bleomycin-induced pulmonary fibrosis in mice via inhibiting inflammatory and fibrotic process.
Chen C, Wang YY, Wang YX, Cheng MQ, Yin JB, Zhang X, Hong ZP
Biochemical and biophysical research communications 2018 Jan 22;495(4):2396-2403
Biochemical and biophysical research communications 2018 Jan 22;495(4):2396-2403
C-MYC and BCL-2 mediate YAP-regulated tumorigenesis in OSCC.
Chen X, Gu W, Wang Q, Fu X, Wang Y, Xu X, Wen Y
Oncotarget 2018 Jan 2;9(1):668-679
Oncotarget 2018 Jan 2;9(1):668-679
Comprehensive Genomic Characterization of RNA-Binding Proteins across Human Cancers.
Wang ZL, Li B, Luo YX, Lin Q, Liu SR, Zhang XQ, Zhou H, Yang JH, Qu LH
Cell reports 2018 Jan 2;22(1):286-298
Cell reports 2018 Jan 2;22(1):286-298
The Potential Roles of the Apoptosis-Related Protein PDRG1 in Diapause Embryo Restarting of Artemia sinica.
Zhang W, Yao F, Zhang H, Li N, Zou X, Sui L, Hou L
International journal of molecular sciences 2018 Jan 2;19(1)
International journal of molecular sciences 2018 Jan 2;19(1)
SOCE induced calcium overload regulates autophagy in acute pancreatitis via calcineurin activation.
Zhu ZD, Yu T, Liu HJ, Jin J, He J
Cell death & disease 2018 Jan 19;9(2):50
Cell death & disease 2018 Jan 19;9(2):50
IcarisideII improves left ventricular remodeling in spontaneously hypertensive rats by inhibiting the ASK1-JNK/p38 signaling pathway.
Wu Y, Qian Z, Fu S, Yue Y, Li Y, Sun R, Huang B, Yang D
European journal of pharmacology 2018 Jan 15;819:68-79
European journal of pharmacology 2018 Jan 15;819:68-79
FBXO2, a novel marker for metastasis in human gastric cancer.
Sun X, Wang T, Guan ZR, Zhang C, Chen Y, Jin J, Hua D
Biochemical and biophysical research communications 2018 Jan 15;495(3):2158-2164
Biochemical and biophysical research communications 2018 Jan 15;495(3):2158-2164
SIRT3 prevents angiotensin II-induced renal tubular epithelial-mesenchymal transition by ameliorating oxidative stress and mitochondrial dysfunction.
He P, Li Z, Yue Z, Gao H, Feng G, Wang P, Huang Y, Luo W, Hong H, Liang L, Chen S, Liu P
Molecular and cellular endocrinology 2018 Jan 15;460:1-13
Molecular and cellular endocrinology 2018 Jan 15;460:1-13
Exosomes derived from imatinib-resistant chronic myeloid leukemia cells mediate a horizontal transfer of drug-resistant trait by delivering miR-365.
Min QH, Wang XZ, Zhang J, Chen QG, Li SQ, Liu XQ, Li J, Liu J, Yang WM, Jiang YH, Xu YM, Lin J, Gao QF, Sun F, Zhang L, Huang B
Experimental cell research 2018 Jan 15;362(2):386-393
Experimental cell research 2018 Jan 15;362(2):386-393
Co-expression analysis revealed PTCH1-3'UTR promoted cell migration and invasion by activating miR-101-3p/SLC39A6 axis in non-small cell lung cancer: implicating the novel function of PTCH1.
Wan X, Kong Z, Chu K, Yi C, Hu J, Qin R, Zhao C, Fu F, Wu H, Li Y, Huang Y
Oncotarget 2018 Jan 12;9(4):4798-4813
Oncotarget 2018 Jan 12;9(4):4798-4813
Inhibition of autophagy-attenuated calcium oxalate crystal-induced renal tubular epithelial cell injury in vivo and in vitro.
Liu Y, Li D, He Z, Liu Q, Wu J, Guan X, Tao Z, Deng Y
Oncotarget 2018 Jan 12;9(4):4571-4582
Oncotarget 2018 Jan 12;9(4):4571-4582
MicroRNA-200a confers chemoresistance by antagonizing TP53INP1 and YAP1 in human breast cancer.
Yu SJ, Yang L, Hong Q, Kuang XY, Di GH, Shao ZM
BMC cancer 2018 Jan 12;18(1):74
BMC cancer 2018 Jan 12;18(1):74
Pharmacological Investigation of the Anti-Inflammation and Anti-Oxidation Activities of Diallyl Disulfide in a Rat Emphysema Model Induced by Cigarette Smoke Extract.
Liu Y, Li A, Feng X, Sun X, Zhu X, Zhao Z
Nutrients 2018 Jan 12;10(1)
Nutrients 2018 Jan 12;10(1)
GBP3 promotes glioma cell proliferation via SQSTM1/p62-ERK1/2 axis.
Xu H, Sun L, Zheng Y, Yu S, Ou-Yang J, Han H, Dai X, Yu X, Li M, Lan Q
Biochemical and biophysical research communications 2018 Jan 1;495(1):446-453
Biochemical and biophysical research communications 2018 Jan 1;495(1):446-453
Protein Kinase A/CREB Signaling Prevents Adriamycin-Induced Podocyte Apoptosis via Upregulation of Mitochondrial Respiratory Chain Complexes.
Xie K, Zhu M, Xiang P, Chen X, Kasimumali A, Lu R, Wang Q, Mou S, Ni Z, Gu L, Pang H
Molecular and cellular biology 2018 Jan 1;38(1)
Molecular and cellular biology 2018 Jan 1;38(1)
MiR-208a-3p aggravates autophagy through the PDCD4-ATG5 pathway in Ang II-induced H9c2 cardiomyoblasts.
Wang L, Ye N, Lian X, Peng F, Zhang H, Gong H
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Feb;98:1-8
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Feb;98:1-8
The E3 ubiquitin ligase MuRF2 attenuates LPS-induced macrophage activation by inhibiting production of inflammatory cytokines and migration.
Bian H, Gao S, Zhang D, Zhao Q, Li F, Li X, Sun S, Song S, Li T, Zhu Q, Ren W, Qin C, Qi J
FEBS open bio 2018 Feb;8(2):234-243
FEBS open bio 2018 Feb;8(2):234-243
Exosomes From Adipose-Derived Stem Cells Attenuate Adipose Inflammation and Obesity Through Polarizing M2 Macrophages and Beiging in White Adipose Tissue.
Zhao H, Shang Q, Pan Z, Bai Y, Li Z, Zhang H, Zhang Q, Guo C, Zhang L, Wang Q
Diabetes 2018 Feb;67(2):235-247
Diabetes 2018 Feb;67(2):235-247
Speckle-Type POZ Protein Down-Regulates Matrix Metalloproteinase 2 Expression via Sp1/PI3K/Akt Signaling Pathway in Colorectal Cancer.
Zhang S, Xiao J, Chai Y, Hong Z, Liu Z, Yuan R, Luo Z, Zhou X, Lucero-Prisno DE III, Huang K
Digestive diseases and sciences 2018 Feb;63(2):395-402
Digestive diseases and sciences 2018 Feb;63(2):395-402
Proteasome-mediated degradation of collagen III by cortisol in amnion fibroblasts.
Mi Y, Wang W, Lu J, Zhang C, Wang Y, Ying H, Sun K
Journal of molecular endocrinology 2018 Feb;60(2):45-54
Journal of molecular endocrinology 2018 Feb;60(2):45-54
Telbivudine attenuates UUO-induced renal fibrosis via TGF-β/Smad and NF-κB signaling.
Chen J, Li D
International immunopharmacology 2018 Feb;55:1-8
International immunopharmacology 2018 Feb;55:1-8
Clinical significance of C/D box small nucleolar RNA U76 as an oncogene and a prognostic biomarker in hepatocellular carcinoma.
Wu L, Chang L, Wang H, Ma W, Peng Q, Yuan Y
Clinics and research in hepatology and gastroenterology 2018 Feb;42(1):82-91
Clinics and research in hepatology and gastroenterology 2018 Feb;42(1):82-91
Fungal β-Glucan Activates the NLRP3 Inflammasome in Human Bronchial Epithelial Cells Through ROS Production.
Huang Y, Hua M, Cui X
Inflammation 2018 Feb;41(1):164-173
Inflammation 2018 Feb;41(1):164-173
NLRC5 deficiency ameliorates diabetic nephropathy through alleviating inflammation.
Luan P, Zhuang J, Zou J, Li H, Shuai P, Xu X, Zhao Y, Kou W, Ji S, Peng A, Xu Y, Su Q, Jian W, Peng W
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2018 Feb;32(2):1070-1084
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2018 Feb;32(2):1070-1084
Coordinated transcription of ANRIL and P16 genes is silenced by P16 DNA methylation.
Gan Y, Ma W, Wang X, Qiao J, Zhang B, Cui C, Liu Z, Deng D
Chinese journal of cancer research = Chung-kuo yen cheng yen chiu 2018 Feb;30(1):93-103
Chinese journal of cancer research = Chung-kuo yen cheng yen chiu 2018 Feb;30(1):93-103
Ephrin receptor A2 is an epithelial cell receptor for Epstein-Barr virus entry.
Zhang H, Li Y, Wang HB, Zhang A, Chen ML, Fang ZX, Dong XD, Li SB, Du Y, Xiong D, He JY, Li MZ, Liu YM, Zhou AJ, Zhong Q, Zeng YX, Kieff E, Zhang Z, Gewurz BE, Zhao B, Zeng MS
Nature microbiology 2018 Feb;3(2):1-8
Nature microbiology 2018 Feb;3(2):1-8
Intrinsic antimicrobial properties of silk spun by genetically modified silkworm strains.
Saviane A, Romoli O, Bozzato A, Freddi G, Cappelletti C, Rosini E, Cappellozza S, Tettamanti G, Sandrelli F
Transgenic research 2018 Feb;27(1):87-101
Transgenic research 2018 Feb;27(1):87-101
Recurrent ECSIT mutation encoding V140A triggers hyperinflammation and promotes hemophagocytic syndrome in extranodal NK/T cell lymphoma.
Wen H, Ma H, Cai Q, Lin S, Lei X, He B, Wu S, Wang Z, Gao Y, Liu W, Liu W, Tao Q, Long Z, Yan M, Li D, Kelley KW, Yang Y, Huang H, Liu Q
Nature medicine 2018 Feb;24(2):154-164
Nature medicine 2018 Feb;24(2):154-164
The long non-coding RNA PVT1 represses ANGPTL4 transcription through binding with EZH2 in trophoblast cell.
Xu Y, Lian Y, Zhang Y, Huang S, Zuo Q, Yang N, Chen Y, Wu D, Sun L
Journal of cellular and molecular medicine 2018 Feb;22(2):1272-1282
Journal of cellular and molecular medicine 2018 Feb;22(2):1272-1282
Quantitative proteomics study of host response to virulent and attenuated pseudorabies virus infection in mouse brain.
Zeng HL, Yu FL, Zhang Z, Yang Q, Jin S, He X, Chen X, Shen Y, Cheng L, Guo L, Xu F
Biochimica et biophysica acta. Proteins and proteomics 2018 Feb;1866(2):307-315
Biochimica et biophysica acta. Proteins and proteomics 2018 Feb;1866(2):307-315
SATB2 suppresses non-small cell lung cancer invasiveness by G9a.
Ma YN, Zhang HY, Fei LR, Zhang MY, Wang CC, Luo Y, Han YC
Clinical and experimental medicine 2018 Feb;18(1):37-44
Clinical and experimental medicine 2018 Feb;18(1):37-44
Propofol protects against endotoxin-induced myocardial injury by inhibiting NF-κB-mediated inflammation.
Yang Z, Cheng F, Yan G, Xiong L, Liu H
Experimental and therapeutic medicine 2018 Feb;15(2):2032-2036
Experimental and therapeutic medicine 2018 Feb;15(2):2032-2036
Annexin A10 contributes to chronic constrictive injury-induced pain through activating ERK1/2 signalling in rats.
Li F, Xue ZY, Liu X, Bai G, Wang YL
The International journal of neuroscience 2018 Feb;128(2):125-132
The International journal of neuroscience 2018 Feb;128(2):125-132
Decreased expression of hepatic cytochrome P450 1A2 (CYP1A2) in a chronic intermittent hypoxia mouse model.
Zhang XB, Zeng YM, Chen XY, Zhang YX, Ding JZ, Xue C
Journal of thoracic disease 2018 Feb;10(2):825-834
Journal of thoracic disease 2018 Feb;10(2):825-834
Fasudil increases temozolomide sensitivity and suppresses temozolomide-resistant glioma growth via inhibiting ROCK2/ABCG2.
Zhang X, Liu X, Zhou W, Yang M, Ding Y, Wang Q, Hu R
Cell death & disease 2018 Feb 7;9(2):190
Cell death & disease 2018 Feb 7;9(2):190
Photosensitization of A2E triggers telomere dysfunction and accelerates retinal pigment epithelium senescence.
Wang J, Feng Y, Han P, Wang F, Luo X, Liang J, Sun X, Ye J, Lu Y, Sun X
Cell death & disease 2018 Feb 7;9(2):178
Cell death & disease 2018 Feb 7;9(2):178
Nicotine promotes atherosclerosis via ROS-NLRP3-mediated endothelial cell pyroptosis.
Wu X, Zhang H, Qi W, Zhang Y, Li J, Li Z, Lin Y, Bai X, Liu X, Chen X, Yang H, Xu C, Zhang Y, Yang B
Cell death & disease 2018 Feb 7;9(2):171
Cell death & disease 2018 Feb 7;9(2):171
Flavagline analog FL3 induces cell cycle arrest in urothelial carcinoma cell of the bladder by inhibiting the Akt/PHB interaction to activate the GADD45α pathway.
Yuan G, Chen X, Liu Z, Wei W, Shu Q, Abou-Hamdan H, Jiang L, Li X, Chen R, Désaubry L, Zhou F, Xie D
Journal of experimental & clinical cancer research : CR 2018 Feb 7;37(1):21
Journal of experimental & clinical cancer research : CR 2018 Feb 7;37(1):21
Silencing Ras-Related C3 Botulinum Toxin Substrate 1 Inhibits Growth and Migration of Hypopharyngeal Squamous Cell Carcinoma via the P38 Mitogen-Activated Protein Kinase Signaling Pathway.
Cheng H, Wang W, Wang G, Wang A, Du L, Lou W
Medical science monitor : international medical journal of experimental and clinical research 2018 Feb 7;24:768-781
Medical science monitor : international medical journal of experimental and clinical research 2018 Feb 7;24:768-781
N-oleoylethanolamide suppresses intimal hyperplasia after balloon injury in rats through AMPK/PPARα pathway.
Zhao Y, Liu Y, Jing Z, Peng L, Jin P, Lin Y, Zhou Y, Yang L, Ren J, Xie Q, Jin X
Biochemical and biophysical research communications 2018 Feb 5;496(2):415-421
Biochemical and biophysical research communications 2018 Feb 5;496(2):415-421
Estrogen directly stimulates LHb expression at the pituitary level during puberty in female zebrafish.
Li G, Tang H, Chen Y, Yin Y, Ogawa S, Liu M, Guo Y, Qi X, Liu Y, Parhar IS, Liu X, Lin H
Molecular and cellular endocrinology 2018 Feb 5;461:1-11
Molecular and cellular endocrinology 2018 Feb 5;461:1-11
Ginsenoside Rg3 sensitizes hypoxic lung cancer cells to cisplatin via blocking of NF-κB mediated epithelial-mesenchymal transition and stemness.
Wang J, Tian L, Khan MN, Zhang L, Chen Q, Zhao Y, Yan Q, Fu L, Liu J
Cancer letters 2018 Feb 28;415:73-85
Cancer letters 2018 Feb 28;415:73-85
Comprehensive integrative analyses identify GLT8D1 and CSNK2B as schizophrenia risk genes.
Yang CP, Li X, Wu Y, Shen Q, Zeng Y, Xiong Q, Wei M, Chen C, Liu J, Huo Y, Li K, Xue G, Yao YG, Zhang C, Li M, Chen Y, Luo XJ
Nature communications 2018 Feb 26;9(1):838
Nature communications 2018 Feb 26;9(1):838
Liver-specific deletion of TSHR inhibits hepatic lipid accumulation in mice.
Zhou L, Wu K, Zhang L, Gao L, Chen S
Biochemical and biophysical research communications 2018 Feb 26;497(1):39-45
Biochemical and biophysical research communications 2018 Feb 26;497(1):39-45
PIM1 mediates epithelial-mesenchymal transition by targeting Smads and c-Myc in the nucleus and potentiates clear-cell renal-cell carcinoma oncogenesis.
Zhao B, Liu L, Mao J, Zhang Z, Wang Q, Li Q
Cell death & disease 2018 Feb 22;9(3):307
Cell death & disease 2018 Feb 22;9(3):307
High-fat Diet Mediates Anxiolytic-like Behaviors in a Time-dependent Manner Through the Regulation of SIRT1 in the Brain.
Xu L, Xu S, Lin L, Gu X, Fu C, Fang Y, Li X, Wang X
Neuroscience 2018 Feb 21;372:237-245
Neuroscience 2018 Feb 21;372:237-245
GRK5 functions as an oncogenic factor in non-small-cell lung cancer.
Jiang LP, Fan SQ, Xiong QX, Zhou YC, Yang ZZ, Li GF, Huang YC, Wu MG, Shen QS, Liu K, Yang CP, Chen YB
Cell death & disease 2018 Feb 20;9(3):295
Cell death & disease 2018 Feb 20;9(3):295
TRAF6 regulates EGF-induced cell transformation and cSCC malignant phenotype through CD147/EGFR.
Zhang X, Wu L, Xiao T, Tang L, Jia X, Guo Y, Zhang J, Li J, He Y, Su J, Zhao S, Tao J, Zhou J, Chen X, Peng C
Oncogenesis 2018 Feb 20;7(2):17
Oncogenesis 2018 Feb 20;7(2):17
Interferon-alpha enhances the antitumour activity of EGFR-targeted therapies by upregulating RIG-I in head and neck squamous cell carcinoma.
Ma H, Jin S, Yang W, Zhou G, Zhao M, Fang S, Zhang Z, Hu J
British journal of cancer 2018 Feb 20;118(4):509-521
British journal of cancer 2018 Feb 20;118(4):509-521
Upregulation of kinesin family member 4A enhanced cell proliferation via activation of Akt signaling and predicted a poor prognosis in hepatocellular carcinoma.
Huang Y, Wang H, Lian Y, Wu X, Zhou L, Wang J, Deng M, Huang Y
Cell death & disease 2018 Feb 2;9(2):141
Cell death & disease 2018 Feb 2;9(2):141
NIT1 suppresses tumour proliferation by activating the TGFβ1-Smad2/3 signalling pathway in colorectal cancer.
Lin C, Zhang J, Lu Y, Li X, Zhang W, Zhang W, Lin W, Zheng L, Li X
Cell death & disease 2018 Feb 15;9(3):263
Cell death & disease 2018 Feb 15;9(3):263
Molecular adaptations of adipose tissue to 6 weeks of morning fasting vs. daily breakfast consumption in lean and obese adults.
Gonzalez JT, Richardson JD, Chowdhury EA, Koumanov F, Holman GD, Cooper S, Thompson D, Tsintzas K, Betts JA
The Journal of physiology 2018 Feb 15;596(4):609-622
The Journal of physiology 2018 Feb 15;596(4):609-622
Hypoxia Activates Src and Promotes Endocytosis Which Decreases MMP-2 Activity and Aggravates Renal Interstitial Fibrosis.
Cheng Z, Liu L, Wang Z, Cai Y, Xu Q, Chen P
International journal of molecular sciences 2018 Feb 15;19(2)
International journal of molecular sciences 2018 Feb 15;19(2)
hPMSC transplantation restoring ovarian function in premature ovarian failure mice is associated with change of Th17/Tc17 and Th17/Treg cell ratios through the PI3K/Akt signal pathway.
Yin N, Wang Y, Lu X, Liu R, Zhang L, Zhao W, Yuan W, Luo Q, Wu H, Luan X, Zhang H
Stem cell research & therapy 2018 Feb 14;9(1):37
Stem cell research & therapy 2018 Feb 14;9(1):37
Polycystin-2 is an essential ion channel subunit in the primary cilium of the renal collecting duct epithelium.
Liu X, Vien T, Duan J, Sheu SH, DeCaen PG, Clapham DE
eLife 2018 Feb 14;7
eLife 2018 Feb 14;7
MYL6B, a myosin light chain, promotes MDM2-mediated p53 degradation and drives HCC development.
Xie X, Wang X, Liao W, Fei R, Wu N, Cong X, Chen Q, Wei L, Wang Y, Chen H
Journal of experimental & clinical cancer research : CR 2018 Feb 13;37(1):28
Journal of experimental & clinical cancer research : CR 2018 Feb 13;37(1):28
MicroRNA-29a mitigation of toll-like receptor 2 and 4 signaling and alleviation of obstructive jaundice-induced fibrosis in mice.
Lin YC, Wang FS, Yang YL, Chuang YT, Huang YH
Biochemical and biophysical research communications 2018 Feb 12;496(3):880-886
Biochemical and biophysical research communications 2018 Feb 12;496(3):880-886
Ursolic Acid Attenuates High Glucose-Mediated Mesangial Cell Injury by Inhibiting the Phosphatidylinositol 3-Kinase/Akt/Mammalian Target of Rapamycin (PI3K/Akt/mTOR) Signaling Pathway.
Wang EM, Fan QL, Yue Y, Xu L
Medical science monitor : international medical journal of experimental and clinical research 2018 Feb 11;24:846-854
Medical science monitor : international medical journal of experimental and clinical research 2018 Feb 11;24:846-854
Overcoming STC2 mediated drug resistance through drug and gene co-delivery by PHB-PDMAEMA cationic polyester in liver cancer cells.
Cheng H, Wu Z, Wu C, Wang X, Liow SS, Li Z, Wu YL
Materials science & engineering. C, Materials for biological applications 2018 Feb 1;83:210-217
Materials science & engineering. C, Materials for biological applications 2018 Feb 1;83:210-217
AF119895 regulates NXF3 expression to promote migration and invasion of hepatocellular carcinoma through an interaction with miR-6508-3p.
Zeng T, Wang D, Chen J, Chen K, Yu G, Chen Q, Liu Y, Yan S, Zhu L, Zhou H, Huang A, Tang H
Experimental cell research 2018 Feb 1;363(1):129-139
Experimental cell research 2018 Feb 1;363(1):129-139
Bone marrow mesenchymal stromal cells alleviate brain white matter injury via the enhanced proliferation of oligodendrocyte progenitor cells in focal cerebral ischemic rats.
Yu X, Wu H, Zhao Y, Guo Y, Chen Y, Dong P, Mu Q, Wang X, Wang X
Brain research 2018 Feb 1;1680:127-136
Brain research 2018 Feb 1;1680:127-136
Truncated SALL1 Impedes Primary Cilia Function in Townes-Brocks Syndrome.
Bozal-Basterra L, Martín-Ruíz I, Pirone L, Liang Y, Sigurðsson JO, Gonzalez-Santamarta M, Giordano I, Gabicagogeascoa E, de Luca A, Rodríguez JA, Wilkie AOM, Kohlhase J, Eastwood D, Yale C, Olsen JV, Rauchman M, Anderson KV, Sutherland JD, Barrio R
American journal of human genetics 2018 Feb 1;102(2):249-265
American journal of human genetics 2018 Feb 1;102(2):249-265
Novel synthetic 4-chlorobenzoyl berbamine inhibits c-Myc expression and induces apoptosis of diffuse large B cell lymphoma cells.
Zhang L, Tong J, He X, Liang Y, Zhu L, Xu R, Zhao X
Annals of hematology 2018 Dec;97(12):2353-2362
Annals of hematology 2018 Dec;97(12):2353-2362
Quercetin ameliorates pulmonary fibrosis by inhibiting SphK1/S1P signaling.
Zhang X, Cai Y, Zhang W, Chen X
Biochemistry and cell biology = Biochimie et biologie cellulaire 2018 Dec;96(6):742-751
Biochemistry and cell biology = Biochimie et biologie cellulaire 2018 Dec;96(6):742-751
Red nucleus interleukin-1β evokes tactile allodynia through activation of JAK/STAT3 and JNK signaling pathways.
Guo YJ, Li HN, Ding CP, Han SP, Wang JY
Journal of neuroscience research 2018 Dec;96(12):1847-1861
Journal of neuroscience research 2018 Dec;96(12):1847-1861
Apolipoprotein E Exerts a Whole-Brain Protective Property by Promoting M1? Microglia Quiescence After Experimental Subarachnoid Hemorrhage in Mice.
Pang J, Peng J, Matei N, Yang P, Kuai L, Wu Y, Chen L, Vitek MP, Li F, Sun X, Zhang JH, Jiang Y
Translational stroke research 2018 Dec;9(6):654-668
Translational stroke research 2018 Dec;9(6):654-668
IL-23-induced macrophage polarization and its pathological roles in mice with imiquimod-induced psoriasis.
Hou Y, Zhu L, Tian H, Sun HX, Wang R, Zhang L, Zhao Y
Protein & cell 2018 Dec;9(12):1027-1038
Protein & cell 2018 Dec;9(12):1027-1038
Autophagy participates in innate immune defense in lamprey.
Luo L, Lu J, Wang Q, Chen S, Xu A, Yuan S
Fish & shellfish immunology 2018 Dec;83:416-424
Fish & shellfish immunology 2018 Dec;83:416-424
Establishing a dual knock-out cell line by lentivirus based combined CRISPR/Cas9 and Loxp/Cre system.
Li Y, Zhang W, Zhao J, Li S, Shan L, Zhu J, Li Y, Zhu H, Mao Q, Xia H
Cytotechnology 2018 Dec;70(6):1595-1605
Cytotechnology 2018 Dec;70(6):1595-1605
Buffalo oocyte-secreted factors promote cumulus cells apoptosis and the rate of cGMP production but not steroidogenesis.
Moussa M, Li MQ, Zheng HY, Yang CY, Yan SF, Yu NQ, Huang JX, Shang JH
Reproduction in domestic animals = Zuchthygiene 2018 Dec;53(6):1523-1529
Reproduction in domestic animals = Zuchthygiene 2018 Dec;53(6):1523-1529
Prolyl hydroxylases positively regulated LPS-induced inflammation in human gingival fibroblasts via TLR4/MyD88-mediated AKT/NF-κB and MAPK pathways.
Shang L, Wang T, Tong D, Kang W, Liang Q, Ge S
Cell proliferation 2018 Dec;51(6):e12516
Cell proliferation 2018 Dec;51(6):e12516
Overexpression of CXCL2 inhibits cell proliferation and promotes apoptosis in hepatocellular carcinoma.
Ding J, Xu K, Zhang J, Lin B, Wang Y, Yin S, Xie H, Zhou L, Zheng S
BMB reports 2018 Dec;51(12):630-635
BMB reports 2018 Dec;51(12):630-635
PI3K/Akt signaling pathway and Hsp70 activate in hippocampus of rats with chronic manganese sulfate exposure.
Cheng H, Xia B, Su C, Chen K, Chen X, Chen P, Zou Y, Yang X
Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS) 2018 Dec;50:332-338
Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS) 2018 Dec;50:332-338
Klotho gene-modified BMSCs showed elevated antifibrotic effects by inhibiting the Wnt/β-catenin pathway in kidneys after acute injury.
Zhang F, Wan X, Cao YZ, Sun D, Cao CC
Cell biology international 2018 Dec;42(12):1670-1679
Cell biology international 2018 Dec;42(12):1670-1679
miR‑29a suppresses the growth and metastasis of hepatocellular carcinoma through IFITM3.
Liang Y, Li E, Min J, Gong C, Gao J, Ai J, Liao W, Wu L
Oncology reports 2018 Dec;40(6):3261-3272
Oncology reports 2018 Dec;40(6):3261-3272
The Scorpion Venom Peptide Smp76 Inhibits Viral Infection by Regulating Type-I Interferon Response.
Ji Z, Li F, Xia Z, Guo X, Gao M, Sun F, Cheng Y, Wu Y, Li W, Ali SA, Cao Z
Virologica Sinica 2018 Dec;33(6):545-556
Virologica Sinica 2018 Dec;33(6):545-556
Elevating ATP-binding cassette transporter G1 improves re-endothelialization function of endothelial progenitor cells via Lyn/Akt/eNOS in diabetic mice.
Shi Y, Lv X, Liu Y, Li B, Liu M, Yan M, Liu Y, Li Q, Zhang X, He S, Zhu M, He J, Zhu Y, Zhu Y, Ai D
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2018 Dec;32(12):6525-6536
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2018 Dec;32(12):6525-6536
Phenethyl isothiocyanate inhibits colorectal cancer stem cells by suppressing Wnt/β-catenin pathway.
Chen Y, Li Y, Wang XQ, Meng Y, Zhang Q, Zhu JY, Chen JQ, Cao WS, Wang XQ, Xie CF, Li XT, Geng SS, Wu JS, Zhong CY, Han HY
Phytotherapy research : PTR 2018 Dec;32(12):2447-2455
Phytotherapy research : PTR 2018 Dec;32(12):2447-2455
MicroRNA-146b-3p Promotes Cell Metastasis by Directly Targeting NF2 in Human Papillary Thyroid Cancer.
Yu C, Zhang L, Luo D, Yan F, Liu J, Shao S, Zhao L, Jin T, Zhao J, Gao L
Thyroid : official journal of the American Thyroid Association 2018 Dec;28(12):1627-1641
Thyroid : official journal of the American Thyroid Association 2018 Dec;28(12):1627-1641
Expression Analysis of ACSL5 and Wnt2B in Human Congenital Pulmonary Airway Malformations.
Qu Y, Liu D, Jia H, Zhou X
The Journal of surgical research 2018 Dec;232:128-136
The Journal of surgical research 2018 Dec;232:128-136
Effects of mdig on proliferation and apoptosis of lung cancer cells.
Xu X, Cao L, Zhang Y, Lian H, Sun Z, Cui Y
Oncology letters 2018 Dec;16(6):7146-7151
Oncology letters 2018 Dec;16(6):7146-7151
Influencing mechanism of magnolol on expression of BDNF and Bax in rats with cerebral ischemic stroke.
Liu Z, Xie J, Lin K, Qi L
Experimental and therapeutic medicine 2018 Dec;16(6):4423-4428
Experimental and therapeutic medicine 2018 Dec;16(6):4423-4428
Regulation of hippocampal long term depression by Neuroligin 1.
Dang R, Qi J, Liu A, Ren Q, Lv D, Han L, Zhou Z, Cao F, Xie W, Jia Z
Neuropharmacology 2018 Dec;143:205-216
Neuropharmacology 2018 Dec;143:205-216
Cathelicidin-WA attenuates LPS-induced inflammation and redox imbalance through activation of AMPK signaling.
Wu W, Wang S, Liu Q, Wang X, Shan T, Wang Y
Free radical biology & medicine 2018 Dec;129:338-353
Free radical biology & medicine 2018 Dec;129:338-353
Mechanism and prognostic value of indoleamine 2,3-dioxygenase 1 expressed in hepatocellular carcinoma.
Li S, Han X, Lyu N, Xie Q, Deng H, Mu L, Pan T, Huang X, Wang X, Shi Y, Zhao M
Cancer science 2018 Dec;109(12):3726-3736
Cancer science 2018 Dec;109(12):3726-3736
Transcription factor 7-like 2 controls matrix degradation through nuclear factor κB signaling and is repressed by microRNA-155 in nucleus pulposus cells.
Sun J, Hong J, Sun S, Wang X, Peng Y, Zhou J, Huang Y, Li S, Chen W, Li C, Xu K, Ye W
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Dec;108:646-655
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Dec;108:646-655
PNMA1, regulated by miR-33a-5p, promotes proliferation and EMT in hepatocellular carcinoma by activating the Wnt/β-catenin pathway.
Liu P, Chen B, Gu Y, Liu Q
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Dec;108:492-499
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Dec;108:492-499
Dynasore-induced potent ubiquitylation of the exon 19 deletion mutant of epidermal growth factor receptor suppresses cell growth and migration in non-small cell lung cancer.
Wang T, Wang D, Zhang Y, Zhang J, Sun X, Wu Y, Wang S, Zhang Y, Xu L, Kong Q, Gao Y, Wu Y, Liu F, Liu S, Zhang Y, Lei T, Liu H
The international journal of biochemistry & cell biology 2018 Dec;105:1-12
The international journal of biochemistry & cell biology 2018 Dec;105:1-12
A novel pathway of LPS uptake through syndecan-1 leading to pyroptotic cell death.
Yokoyama S, Cai Y, Murata M, Tomita T, Yoneda M, Xu L, Pilon AL, Cachau RE, Kimura S
eLife 2018 Dec 7;7
eLife 2018 Dec 7;7
A Simplified System to Express Circularized Inhibitors of miRNA for Stable and Potent Suppression of miRNA Functions.
Shu Y, Wu K, Zeng Z, Huang S, Ji X, Yuan C, Zhang L, Liu W, Huang B, Feng Y, Zhang B, Dai Z, Shen Y, Luo W, Wang X, Liu B, Lei Y, Ye Z, Zhao L, Cao D, Yang L, Chen X, Luu HH, Reid RR, Wolf JM, Lee MJ, He TC
Molecular therapy. Nucleic acids 2018 Dec 7;13:556-567
Molecular therapy. Nucleic acids 2018 Dec 7;13:556-567
NR2C2-uORF targeting UCA1-miR-627-5p-NR2C2 feedback loop to regulate the malignant behaviors of glioma cells.
Fan Z, Zheng J, Xue Y, Liu X, Wang D, Yang C, Ma J, Liu L, Ruan X, Wang Z, Liu Y
Cell death & disease 2018 Dec 5;9(12):1165
Cell death & disease 2018 Dec 5;9(12):1165
MAN1B1 is associated with poor prognosis and modulates proliferation and apoptosis in bladder cancer.
Wang HF, Wu JH, Gai JW, Yang SQ, Ma QT, Ma HS, Feng Q
Gene 2018 Dec 30;679:314-319
Gene 2018 Dec 30;679:314-319
LINC00052/miR-101-3p axis inhibits cell proliferation and metastasis by targeting SOX9 in hepatocellular carcinoma.
Yan S, Shan X, Chen K, Liu Y, Yu G, Chen Q, Zeng T, Zhu L, Dang H, Chen F, Ling J, Huang A, Tang H
Gene 2018 Dec 30;679:138-149
Gene 2018 Dec 30;679:138-149
Systematic analysis of synergistic proteome modulations in a drug combination of cisplatin and MLN4924.
Megger DA, Abou-Eid S, Zülch B, Sitek B
Molecular omics 2018 Dec 3;14(6):450-457
Molecular omics 2018 Dec 3;14(6):450-457
4'-hydroxywogonin inhibits colorectal cancer angiogenesis by disrupting PI3K/AKT signaling.
Sun D, Zhang F, Qian J, Shen W, Fan H, Tan J, Li L, Xu C, Yang Y, Cheng H
Chemico-biological interactions 2018 Dec 25;296:26-33
Chemico-biological interactions 2018 Dec 25;296:26-33
Anti-tumoral potential of MDA19 in human osteosarcoma via suppressing PI3K/Akt/mTOR signaling pathway.
Liu B, Xu L, Dai EN, Tian JX, Li JM
Bioscience reports 2018 Dec 21;38(6)
Bioscience reports 2018 Dec 21;38(6)
Jian-Pi-Yi-Shen Formula ameliorates chronic kidney disease: involvement of mitochondrial quality control network.
Liu X, Chen J, Liu X, Wang D, Zheng P, Qi A, Yi T, Li S
BMC complementary and alternative medicine 2018 Dec 20;18(1):340
BMC complementary and alternative medicine 2018 Dec 20;18(1):340
Gli2 modulates cell cycle re-entry through autophagy-mediated regulation of the length of primary cilia.
Hsiao CJ, Chang CH, Ibrahim RB, Lin IH, Wang CH, Wang WJ, Tsai JW
Journal of cell science 2018 Dec 17;131(24)
Journal of cell science 2018 Dec 17;131(24)
CVB3 Nonstructural 2A Protein Modulates SREBP1a Signaling via the MEK/ERK Pathway.
Wang L, Xie W, Zhang L, Li D, Yu H, Xiong J, Peng J, Qiu J, Sheng H, He X, Zhang K
Journal of virology 2018 Dec 15;92(24)
Journal of virology 2018 Dec 15;92(24)
Perigestational exposure to low doses of PBDE-47 induces excessive ER stress, defective autophagy and the resultant apoptosis contributing to maternal thyroid toxicity.
Li P, Liu L, Zhou G, Tian Z, Luo C, Xia T, Chen J, Niu Q, Dong L, Zhao Q, Wang A, Zhang S
The Science of the total environment 2018 Dec 15;645:363-371
The Science of the total environment 2018 Dec 15;645:363-371
Dexmedetomidine alleviates cerebral ischemia-reperfusion injury by inhibiting endoplasmic reticulum stress dependent apoptosis through the PERK-CHOP-Caspase-11 pathway.
Liu C, Fu Q, Mu R, Wang F, Zhou C, Zhang L, Yu B, Zhang Y, Fang T, Tian F
Brain research 2018 Dec 15;1701:246-254
Brain research 2018 Dec 15;1701:246-254
Metformin regulates atrial SK2 and SK3 expression through inhibiting the PKC/ERK signaling pathway in type 2 diabetic rats.
Liu CH, Hua N, Fu X, Pan YL, Li B, Li XD
BMC cardiovascular disorders 2018 Dec 13;18(1):236
BMC cardiovascular disorders 2018 Dec 13;18(1):236
Epigenetic suppression of E-cadherin expression by Snail2 during the metastasis of colorectal cancer.
Hu Y, Dai M, Zheng Y, Wu J, Yu B, Zhang H, Kong W, Wu H, Yu X
Clinical epigenetics 2018 Dec 12;10(1):154
Clinical epigenetics 2018 Dec 12;10(1):154
Co-targeting PLK1 and mTOR induces synergistic inhibitory effects against esophageal squamous cell carcinoma.
Liu TT, Yang KX, Yu J, Cao YY, Ren JS, Hao JJ, Pan BQ, Ma S, Yang LY, Cai Y, Wang MR, Zhang Y
Journal of molecular medicine (Berlin, Germany) 2018 Aug;96(8):807-817
Journal of molecular medicine (Berlin, Germany) 2018 Aug;96(8):807-817
miR-128-3p regulates 3T3-L1 adipogenesis and lipolysis by targeting Pparg and Sertad2.
Chen C, Deng Y, Hu X, Ren H, Zhu J, Fu S, Xie J, Peng Y
Journal of physiology and biochemistry 2018 Aug;74(3):381-393
Journal of physiology and biochemistry 2018 Aug;74(3):381-393
Radiosensitizing effects of miR-18a-5p on lung cancer stem-like cells via downregulating both ATM and HIF-1α.
Chen X, Wu L, Li D, Xu Y, Zhang L, Niu K, Kong R, Gu J, Xu Z, Chen Z, Sun J
Cancer medicine 2018 Aug;7(8):3834-3847
Cancer medicine 2018 Aug;7(8):3834-3847
NRG1 regulates redox homeostasis via NRF2 in papillary thyroid cancer.
Zhang TT, Qu N, Sun GH, Zhang L, Wang YJ, Mu XM, Wei WJ, Wang YL, Wang Y, Ji QH, Zhu YX, Shi RL
International journal of oncology 2018 Aug;53(2):685-693
International journal of oncology 2018 Aug;53(2):685-693
Overexpression of PRDM13 inhibits glioma cells via Rho and GTP enzyme activation protein.
Zhang L, Cao H, He T, Yang J, Tao H, Wang Y, Hu Q
International journal of molecular medicine 2018 Aug;42(2):966-974
International journal of molecular medicine 2018 Aug;42(2):966-974
Overexpression of FOXQ1 enhances anti-senescence and migration effects of human umbilical cord mesenchymal stem cells in vitro and in vivo.
Zhang T, Wang P, Liu Y, Zhou J, Shi Z, Cheng K, Huang T, Wang X, Yang GL, Yang B, Ma S, Guan F
Cell and tissue research 2018 Aug;373(2):379-393
Cell and tissue research 2018 Aug;373(2):379-393
Scribble influences cyst formation in autosomal-dominant polycystic kidney disease by regulating Hippo signaling pathway.
Xu D, Lv J, He L, Fu L, Hu R, Cao Y, Mei C
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2018 Aug;32(8):4394-4407
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2018 Aug;32(8):4394-4407
Increased Expression of NDRG3 in Mouse Uterus During Embryo Implantation and in Mouse Endometrial Stromal Cells During In Vitro Decidualization.
Yang Q, Zhang X, Shi Y, He YP, Sun ZG, Shi HJ, Wang J
Reproductive sciences (Thousand Oaks, Calif.) 2018 Aug;25(8):1197-1207
Reproductive sciences (Thousand Oaks, Calif.) 2018 Aug;25(8):1197-1207
LncRNA BDNF-AS inhibits proliferation, migration, invasion and EMT in oesophageal cancer cells by targeting miR-214.
Zhao H, Diao C, Wang X, Xie Y, Liu Y, Gao X, Han J, Li S
Journal of cellular and molecular medicine 2018 Aug;22(8):3729-3739
Journal of cellular and molecular medicine 2018 Aug;22(8):3729-3739
Revealing A-Raf functions through its interactome.
Zhang XY, Guo H, Han B, Zhang XM, Huang Y, Yang Y, Liu Y, Guo XX, Hao Q, An S, Xu TR
Biochimica et biophysica acta. Proteins and proteomics 2018 Aug;1866(8):849-856
Biochimica et biophysica acta. Proteins and proteomics 2018 Aug;1866(8):849-856
miR-205-5p inhibits cell migration and invasion in prostatic carcinoma by targeting ZEB1.
Li L, Li S
Oncology letters 2018 Aug;16(2):1715-1721
Oncology letters 2018 Aug;16(2):1715-1721
Peri-ovarian adipose tissue contributes to intraovarian control during folliculogenesis in mice.
Yang L, Chen L, Lu X, Tan A, Chen Y, Li Y, Peng X, Yuan S, Cai D, Yu Y
Reproduction (Cambridge, England) 2018 Aug;156(2):133-144
Reproduction (Cambridge, England) 2018 Aug;156(2):133-144
MicroRNA-135a inhibits cardiac fibrosis induced by isoproterenol via TRPM7 channel.
Wu Y, Liu Y, Pan Y, Lu C, Xu H, Wang X, Liu T, Feng K, Tang Y
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Aug;104:252-260
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Aug;104:252-260
ITGBL1 promotes migration, invasion and predicts a poor prognosis in colorectal cancer.
Qiu X, Feng JR, Qiu J, Liu L, Xie Y, Zhang YP, Liu J, Zhao Q
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Aug;104:172-180
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Aug;104:172-180
Warfarin and vitamin K epoxide reductase: a molecular accounting for observed inhibition.
Wu S, Chen X, Jin DY, Stafford DW, Pedersen LG, Tie JK
Blood 2018 Aug 9;132(6):647-657
Blood 2018 Aug 9;132(6):647-657
Anillin is required for tumor growth and regulated by miR-15a/miR-16-1 in HBV-related hepatocellular carcinoma.
Lian YF, Huang YL, Wang JL, Deng MH, Xia TL, Zeng MS, Chen MS, Wang HB, Huang YH
Aging 2018 Aug 9;10(8):1884-1901
Aging 2018 Aug 9;10(8):1884-1901
HMGB1 knockdown increases MM cell vulnerability by regulating autophagy and DNA damage repair.
Guo X, He D, Zhang E, Chen J, Chen Q, Li Y, Yang L, Yang Y, Zhao Y, Wang G, He J, Cai Z
Journal of experimental & clinical cancer research : CR 2018 Aug 29;37(1):205
Journal of experimental & clinical cancer research : CR 2018 Aug 29;37(1):205
Ubiquitin-conjugating enzyme UBE2J1 negatively modulates interferon pathway and promotes RNA virus infection.
Feng T, Deng L, Lu X, Pan W, Wu Q, Dai J
Virology journal 2018 Aug 29;15(1):132
Virology journal 2018 Aug 29;15(1):132
MALAT1-miR663a negative feedback loop in colon cancer cell functions through direct miRNA-lncRNA binding.
Tian W, Du Y, Ma Y, Gu L, Zhou J, Deng D
Cell death & disease 2018 Aug 28;9(9):857
Cell death & disease 2018 Aug 28;9(9):857
Hepatocyte Wnts Are Dispensable During Diethylnitrosamine and Carbon Tetrachloride-Induced Injury and Hepatocellular Cancer.
Preziosi M, Poddar M, Singh S, Monga SP
Gene expression 2018 Aug 22;18(3):209-219
Gene expression 2018 Aug 22;18(3):209-219
Cold atmospheric plasma conveys selectivity on triple negative breast cancer cells both in vitro and in vivo.
Xiang L, Xu X, Zhang S, Cai D, Dai X
Free radical biology & medicine 2018 Aug 20;124:205-213
Free radical biology & medicine 2018 Aug 20;124:205-213
Increased Expression of CD81 in Breast Cancer Tissue is Associated with Reduced Patient Prognosis and Increased Cell Migration and Proliferation in MDA-MB-231 and MDA-MB-435S Human Breast Cancer Cell Lines In Vitro.
Zhang N, Zuo L, Zheng H, Li G, Hu X
Medical science monitor : international medical journal of experimental and clinical research 2018 Aug 17;24:5739-5747
Medical science monitor : international medical journal of experimental and clinical research 2018 Aug 17;24:5739-5747
Motoneuron Wnts regulate neuromuscular junction development.
Shen C, Li L, Zhao K, Bai L, Wang A, Shu X, Xiao Y, Zhang J, Zhang K, Hui T, Chen W, Zhang B, Hsu W, Xiong WC, Mei L
eLife 2018 Aug 16;7
eLife 2018 Aug 16;7
Inhibition of mTORC1 signaling protects kidney from irradiation-induced toxicity via accelerating recovery of renal stem-like cells.
Shao L, Yang W, Xu R, Zhu S, Huang Y, Li H, Wu X, Yue M, Xiong X, Chen X, Kuang B, Fan G, Zhu Q, Zeng H
Stem cell research & therapy 2018 Aug 14;9(1):219
Stem cell research & therapy 2018 Aug 14;9(1):219
Transactive Response DNA-Binding Protein 43 Abnormalities after Traumatic Brain Injury.
Tan XL, Sun M, Brady RD, Liu S, Llanos R, Cheung S, Wright DK, Casillas-Espinosa PM, Sashindranath M, O'Brien TJ, McDonald SJ, Turner BJ, Shultz SR
Journal of neurotrauma 2018 Aug 10;
Journal of neurotrauma 2018 Aug 10;
Antifertility effectiveness of a novel copper-containing intrauterine device material and its influence on the endometrial environment in rats.
Hu S, Wang Y, Ke D, Zhou F, Cheng G, Xia W, Zhu C
Materials science & engineering. C, Materials for biological applications 2018 Aug 1;89:444-455
Materials science & engineering. C, Materials for biological applications 2018 Aug 1;89:444-455
Lanthanum chloride reduces lactate production in primary culture rat cortical astrocytes and suppresses primary co-culture rat cortical astrocyte-neuron lactate transport.
Sun Y, Yang J, Hu X, Gao X, Li Y, Yu M, Liu S, Lu X, Jin C, Wu S, Cai Y
Archives of toxicology 2018 Apr;92(4):1407-1419
Archives of toxicology 2018 Apr;92(4):1407-1419
Interleukin-17A participates in podocyte injury by inducing IL-1β secretion through ROS-NLRP3 inflammasome-caspase-1 pathway.
Yan J, Li Y, Yang H, Zhang L, Yang B, Wang M, Li Q
Scandinavian journal of immunology 2018 Apr;87(4):e12645
Scandinavian journal of immunology 2018 Apr;87(4):e12645
PARP inhibitor olaparib sensitizes cholangiocarcinoma cells to radiation.
Mao Y, Huang X, Shuang Z, Lin G, Wang J, Duan F, Chen J, Li S
Cancer medicine 2018 Apr;7(4):1285-1296
Cancer medicine 2018 Apr;7(4):1285-1296
Gemin5 plays a role in unassembled-U1 snRNA disposal in SMN-deficient cells.
Jiang D, Zou X, Zhang C, Chen J, Li Z, Wang Y, Deng Z, Wang L, Chen S
FEBS letters 2018 Apr;592(8):1400-1411
FEBS letters 2018 Apr;592(8):1400-1411
MDM2 Degrades Deacetylated Nucleolin Through Ubiquitination to Promote Glioma Stem-Like Cell Enrichment for Chemotherapeutic Resistance.
Ko CY, Lin CH, Chuang JY, Chang WC, Hsu TI
Molecular neurobiology 2018 Apr;55(4):3211-3223
Molecular neurobiology 2018 Apr;55(4):3211-3223
Rolipram Attenuates Early Brain Injury Following Experimental Subarachnoid Hemorrhage in Rats: Possibly via Regulating the SIRT1/NF-κB Pathway.
Peng Y, Jin J, Fan L, Xu H, He P, Li J, Chen T, Ruan W, Chen G
Neurochemical research 2018 Apr;43(4):785-795
Neurochemical research 2018 Apr;43(4):785-795
miR‑21‑5p confers doxorubicin resistance in gastric cancer cells by targeting PTEN and TIMP3.
Chen J, Zhou C, Li J, Xiang X, Zhang L, Deng J, Xiong J
International journal of molecular medicine 2018 Apr;41(4):1855-1866
International journal of molecular medicine 2018 Apr;41(4):1855-1866
MiR-151a is involved in the pathogenesis of atopic dermatitis by regulating interleukin-12 receptor β2.
Chen XF, Zhang LJ, Zhang J, Dou X, Shao Y, Jia XJ, Zhang W, Yu B
Experimental dermatology 2018 Apr;27(4):427-432
Experimental dermatology 2018 Apr;27(4):427-432
Targeting P-glycoprotein and SORCIN: Dihydromyricetin strengthens anti-proliferative efficiency of adriamycin via MAPK/ERK and Ca2+ -mediated apoptosis pathways in MCF-7/ADR and K562/ADR.
Sun Y, Wang C, Meng Q, Liu Z, Huo X, Sun P, Sun H, Ma X, Peng J, Liu K
Journal of cellular physiology 2018 Apr;233(4):3066-3079
Journal of cellular physiology 2018 Apr;233(4):3066-3079
TXNDC5 contributes to rheumatoid arthritis by down-regulating IGFBP1 expression.
Li J, Xu B, Wu C, Yan X, Zhang L, Chang X
Clinical and experimental immunology 2018 Apr;192(1):82-94
Clinical and experimental immunology 2018 Apr;192(1):82-94
Phenformin inhibits cell proliferation and induces cell apoptosis and autophagy in cholangiocarcinoma.
Hu S, Ouyang Q, Cheng Q, Wang J, Feng F, Qiao L, Gan W, Shi Y, Wu D, Jiang X
Molecular medicine reports 2018 Apr;17(4):6028-6032
Molecular medicine reports 2018 Apr;17(4):6028-6032
Zoledronic acid sensitizes breast cancer cells to fulvestrant via ERK/HIF-1 pathway inhibition in vivo.
Jia X, Cheng J, Shen Z, Shao Z, Liu G
Molecular medicine reports 2018 Apr;17(4):5470-5476
Molecular medicine reports 2018 Apr;17(4):5470-5476
Effect of TLR4/MyD88 signaling pathway on sepsis-associated acute respiratory distress syndrome in rats, via regulation of macrophage activation and inflammatory response.
Zhou S, Wang G, Zhang W
Experimental and therapeutic medicine 2018 Apr;15(4):3376-3384
Experimental and therapeutic medicine 2018 Apr;15(4):3376-3384
Screening the expression characteristics of several miRNAs in G93A-SOD1 transgenic mouse: altered expression of miRNA-124 is associated with astrocyte differentiation by targeting Sox2 and Sox9.
Zhou F, Zhang C, Guan Y, Chen Y, Lu Q, Jie L, Gao H, Du H, Zhang H, Liu Y, Wang X
Journal of neurochemistry 2018 Apr;145(1):51-67
Journal of neurochemistry 2018 Apr;145(1):51-67
TSR2 Induces laryngeal cancer cell apoptosis through inhibiting NF-κB signaling pathway.
He HJ, Bing H, Liu G
The Laryngoscope 2018 Apr;128(4):E130-E134
The Laryngoscope 2018 Apr;128(4):E130-E134
Icariside II attenuates myocardial fibrosis by inhibiting nuclear factor-κB and the TGF-β1/Smad2 signalling pathway in spontaneously hypertensive rats.
Fu S, Li YL, Wu YT, Yue Y, Qian ZQ, Yang DL
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Apr;100:64-71
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Apr;100:64-71
Apocynum venetum leaf extract reverses depressive-like behaviors in chronically stressed rats by inhibiting oxidative stress and apoptosis.
Li X, Wu T, Yu Z, Li T, Zhang J, Zhang Z, Cai M, Zhang W, Xiang J, Cai D
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Apr;100:394-406
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Apr;100:394-406
Ezrin/NF-κB Pathway Regulates EGF-induced Epithelial-Mesenchymal Transition (EMT), Metastasis, and Progression of Osteosarcoma.
Liu P, Yang P, Zhang Z, Liu M, Hu S
Medical science monitor : international medical journal of experimental and clinical research 2018 Apr 9;24:2098-2108
Medical science monitor : international medical journal of experimental and clinical research 2018 Apr 9;24:2098-2108
Protective effect of methylallyl sulfone in the development of cigarette smoke extract-induced apoptosis in rats and HFL-1 cells.
Li A, Liu Y, Zhu X, Sun X, Feng X, Li D, Zhang J, Zhu M, Zhao Z
Biochemical and biophysical research communications 2018 Apr 6;498(3):627-632
Biochemical and biophysical research communications 2018 Apr 6;498(3):627-632
R-spondin3-LGR4 signaling protects hepatocytes against DMOG-induced hypoxia/reoxygenation injury through activating β-catenin.
Liu S, Yin Y, Yu R, Li Y, Zhang W
Biochemical and biophysical research communications 2018 Apr 30;499(1):59-65
Biochemical and biophysical research communications 2018 Apr 30;499(1):59-65
Down-regulation of miR-10a-5p promotes proliferation and restricts apoptosis via targeting T-box transcription factor 5 in inflamed synoviocytes.
Hussain N, Zhu W, Jiang C, Xu J, Geng M, Wu X, Hussain S, Wang B, Rajoka MSR, Li Y, Tian J, Meng L, Lu S
Bioscience reports 2018 Apr 27;38(2)
Bioscience reports 2018 Apr 27;38(2)
Characterization of RUNX1T1, an Adipogenesis Regulator in Ovine Preadipocyte Differentiation.
Deng K, Ren C, Liu Z, Gao X, Fan Y, Zhang G, Zhang Y, Ma ES, Wang F, You P
International journal of molecular sciences 2018 Apr 26;19(5)
International journal of molecular sciences 2018 Apr 26;19(5)
Ehrlichia chaffeensis TRP75 Interacts with Host Cell Targets Involved in Homeostasis, Cytoskeleton Organization, and Apoptosis Regulation To Promote Infection.
Luo T, Mitra S, McBride JW
mSphere 2018 Apr 25;3(2)
mSphere 2018 Apr 25;3(2)
The LINC01138 drives malignancies via activating arginine methyltransferase 5 in hepatocellular carcinoma.
Li Z, Zhang J, Liu X, Li S, Wang Q, Di Chen, Hu Z, Yu T, Ding J, Li J, Yao M, Fan J, Huang S, Gao Q, Zhao Y, He X
Nature communications 2018 Apr 20;9(1):1572
Nature communications 2018 Apr 20;9(1):1572
RUVBL1, a novel C-RAF-binding protein, activates the RAF/MEK/ERK pathway to promote lung cancer tumorigenesis.
Guo H, Zhang XY, Peng J, Huang Y, Yang Y, Liu Y, Guo XX, Hao Q, An S, Xu TR
Biochemical and biophysical research communications 2018 Apr 15;498(4):932-939
Biochemical and biophysical research communications 2018 Apr 15;498(4):932-939
RGC32 Promotes Bleomycin-Induced Systemic Sclerosis in a Murine Disease Model by Modulating Classically Activated Macrophage Function.
Sun C, Chen SY
Journal of immunology (Baltimore, Md. : 1950) 2018 Apr 15;200(8):2777-2785
Journal of immunology (Baltimore, Md. : 1950) 2018 Apr 15;200(8):2777-2785
Vitamin A pretreatment protects NO-induced bovine mammary epithelial cells from oxidative stress by modulating Nrf2 and NF-κB signaling pathways.
Shi HY, Yan SM, Guo YM, Zhang BQ, Guo XY, Shi BL
Journal of animal science 2018 Apr 14;96(4):1305-1316
Journal of animal science 2018 Apr 14;96(4):1305-1316
gga-miR-451 Negatively Regulates Mycoplasma gallisepticum (HS Strain)-Induced Inflammatory Cytokine Production via Targeting YWHAZ.
Zhao Y, Zhang K, Zou M, Sun Y, Peng X
International journal of molecular sciences 2018 Apr 13;19(4)
International journal of molecular sciences 2018 Apr 13;19(4)
Lysophosphatidic Acid Induces ECM Production via Activation of the Mechanosensitive YAP/TAZ Transcriptional Pathway in Trabecular Meshwork Cells.
Ho LTY, Skiba N, Ullmer C, Rao PV
Investigative ophthalmology & visual science 2018 Apr 1;59(5):1969-1984
Investigative ophthalmology & visual science 2018 Apr 1;59(5):1969-1984
Caspase Inhibition Reduces Hepatic Tissue Factor-Driven Coagulation In Vitro and In Vivo.
Kopec AK, Spada AP, Contreras PC, Mackman N, Luyendyk JP
Toxicological sciences : an official journal of the Society of Toxicology 2018 Apr 1;162(2):396-405
Toxicological sciences : an official journal of the Society of Toxicology 2018 Apr 1;162(2):396-405
IncRNA H19 promotes tongue squamous cell carcinoma progression through β-catenin/GSK3β/EMT signaling via association with EZH2.
Zhang DM, Lin ZY, Yang ZH, Wang YY, Wan D, Zhong JL, Zhuang PL, Huang ZQ, Zhou B, Chen WL
American journal of translational research 2017;9(7):3474-3486
American journal of translational research 2017;9(7):3474-3486
RIZ1 negatively regulates ubiquitin-conjugating enzyme E2C/UbcH10 via targeting c-Myc in meningioma.
Cai Z, Zou Y, Hu H, Lu C, Sun W, Jiang L, Hu G
American journal of translational research 2017;9(5):2645-2655
American journal of translational research 2017;9(5):2645-2655
Down-regulation of miR-125a-5p is associated with salivary adenoid cystic carcinoma progression via targeting p38/JNK/ERK signal pathway.
Liang Y, Ye J, Jiao J, Zhang J, Lu Y, Zhang L, Wan D, Duan L, Wu Y, Zhang B
American journal of translational research 2017;9(3):1101-1113
American journal of translational research 2017;9(3):1101-1113
Upregulation of TSPAN12 is associated with the colorectal cancer growth and metastasis.
Liu J, Chen C, Li G, Chen D, Zhou Q
American journal of translational research 2017;9(2):812-822
American journal of translational research 2017;9(2):812-822
DDX3 binding with CK1ε was closely related to motor neuron degeneration of ALS by affecting neurite outgrowth.
Chen Y, Wang Q, Wang Q, Liu H, Zhou F, Zhang Y, Yuan M, Zhao C, Guan Y, Wang X
American journal of translational research 2017;9(10):4627-4639
American journal of translational research 2017;9(10):4627-4639
Levodopa/Benserazide Loaded Microspheres Alleviate L-dopa Induced Dyskinesia through Preventing the Over-Expression of D1R/Shp-2/ERK1/2 Signaling Pathway in a Rat Model of Parkinson's Disease.
Wan Y, Wu N, Song L, Wang X, Liu Z, Yuan W, Gan J
Frontiers in aging neuroscience 2017;9:331
Frontiers in aging neuroscience 2017;9:331
The role of the chemokine receptor XCR1 in breast cancer cells.
Yang XL, Qi LG, Lin FJ, Ou ZL
Breast cancer (Dove Medical Press) 2017;9:227-236
Breast cancer (Dove Medical Press) 2017;9:227-236
The Frequency-Dependent Aerobic Exercise Effects of Hypothalamic GABAergic Expression and Cardiovascular Functions in Aged Rats.
Li Y, Zhao Z, Cai J, Gu B, Lv Y, Zhao L
Frontiers in aging neuroscience 2017;9:212
Frontiers in aging neuroscience 2017;9:212
Methylation of ZNF331 is an independent prognostic marker of colorectal cancer and promotes colorectal cancer growth.
Wang Y, He T, Herman JG, Linghu E, Yang Y, Fuks F, Zhou F, Song L, Guo M
Clinical epigenetics 2017;9:115
Clinical epigenetics 2017;9:115
Downregulation of Mitochondrial Single Stranded DNA Binding Protein (SSBP1) Induces Mitochondrial Dysfunction and Increases the Radiosensitivity in Non-Small Cell Lung Cancer Cells.
Wang Y, Hu L, Zhang X, Zhao H, Xu H, Wei Y, Jiang H, Xie C, Zhou Y, Zhou F
Journal of Cancer 2017;8(8):1400-1409
Journal of Cancer 2017;8(8):1400-1409
HES1 Promotes Colorectal Cancer Cell Resistance To 5-Fu by Inducing Of EMT and ABC Transporter Proteins.
Sun L, Ke J, He Z, Chen Z, Huang Q, Ai W, Wang G, Wei Y, Zou X, Zhang S, Lan P, Hong C
Journal of Cancer 2017;8(14):2802-2808
Journal of Cancer 2017;8(14):2802-2808
CDC27 Induces Metastasis and Invasion in Colorectal Cancer via the Promotion of Epithelial-To-Mesenchymal Transition.
Qiu L, Tan X, Lin J, Liu RY, Chen S, Geng R, Wu J, Huang W
Journal of Cancer 2017;8(13):2626-2635
Journal of Cancer 2017;8(13):2626-2635
Interferon-α Promotes the Expression of Cancer Stem Cell Markers in Oral Squamous Cell Carcinoma.
Ma H, Jin S, Yang W, Tian Z, Liu S, Wang Y, Zhou G, Zhao M, Gvetadze S, Zhang Z, Hu J
Journal of Cancer 2017;8(12):2384-2393
Journal of Cancer 2017;8(12):2384-2393
In vitro Cytotoxic Activities of the Oral Platinum(IV) Prodrug Oxoplatin and HSP90 Inhibitor Ganetespib against a Panel of Gastric Cancer Cell Lines.
Klameth L, Rath B, Hamilton G
Journal of Cancer 2017;8(10):1733-1743
Journal of Cancer 2017;8(10):1733-1743
Carnosic Acid Alleviates BDL-Induced Liver Fibrosis through miR-29b-3p-Mediated Inhibition of the High-Mobility Group Box 1/Toll-Like Receptor 4 Signaling Pathway in Rats.
Zhang S, Wang Z, Zhu J, Xu T, Zhao Y, Zhao H, Tang F, Li Z, Zhou J, Gao D, Tian X, Yao J
Frontiers in pharmacology 2017;8:976
Frontiers in pharmacology 2017;8:976
Antidiabetic Effect of Tibetan Medicine Tang-Kang-Fu-San in db/db Mice via Activation of PI3K/Akt and AMPK Pathways.
Duan B, Zhao Z, Liao W, Xiong H, Liu S, Yin L, Gao T, Mei Z
Frontiers in pharmacology 2017;8:535
Frontiers in pharmacology 2017;8:535
Fentanyl Promotes Breast Cancer Cell Stemness and Epithelial-Mesenchymal Transition by Upregulating α1, 6-Fucosylation via Wnt/β-Catenin Signaling Pathway.
Yang HF, Yu M, Jin HD, Yao JQ, Lu ZL, Yabasin IB, Yan Q, Wen QP
Frontiers in physiology 2017;8:510
Frontiers in physiology 2017;8:510
Lactobacillus rhamnosus GG Affects Microbiota and Suppresses Autophagy in the Intestines of Pigs Challenged with Salmonella Infantis.
Zhang W, Zhu YH, Yang GY, Liu X, Xia B, Hu X, Su JH, Wang JF
Frontiers in microbiology 2017;8:2705
Frontiers in microbiology 2017;8:2705
Screening and Identification of the Host Proteins Interacting with Toxoplasma gondii Rhoptry Protein ROP16.
Pan M, Zhou Y, Wang Y, Li L, Song Y, Hou L, Zhao J
Frontiers in microbiology 2017;8:2408
Frontiers in microbiology 2017;8:2408
Lab-Attenuated Rabies Virus Causes Abortive Infection and Induces Cytokine Expression in Astrocytes by Activating Mitochondrial Antiviral-Signaling Protein Signaling Pathway.
Tian B, Zhou M, Yang Y, Yu L, Luo Z, Tian D, Wang K, Cui M, Chen H, Fu ZF, Zhao L
Frontiers in immunology 2017;8:2011
Frontiers in immunology 2017;8:2011
Protective Effects of Dioscin against Lipopolysaccharide-Induced Acute Lung Injury through Inhibition of Oxidative Stress and Inflammation.
Yao H, Sun Y, Song S, Qi Y, Tao X, Xu L, Yin L, Han X, Xu Y, Li H, Sun H, Peng J
Frontiers in pharmacology 2017;8:120
Frontiers in pharmacology 2017;8:120
LncRNA ZFAS1 promotes growth and metastasis by regulating BMI1 and ZEB2 in osteosarcoma.
Liu G, Wang L, Han H, Li Y, Lu S, Li T, Cheng C
American journal of cancer research 2017;7(7):1450-1462
American journal of cancer research 2017;7(7):1450-1462
Obatoclax and LY3009120 Efficiently Overcome Vemurafenib Resistance in Differentiated Thyroid Cancer.
Wei WJ, Sun ZK, Shen CT, Song HJ, Zhang XY, Qiu ZL, Luo QY
Theranostics 2017;7(4):987-1001
Theranostics 2017;7(4):987-1001
miR-381-3p suppresses the proliferation of oral squamous cell carcinoma cells by directly targeting FGFR2.
Yang X, Ruan H, Hu X, Cao A, Song L
American journal of cancer research 2017;7(4):913-922
American journal of cancer research 2017;7(4):913-922
NRSN2 promotes osteosarcoma cell proliferation and growth through PI3K/Akt/MTOR and Wnt/β-catenin signaling.
Keremu A, Maimaiti X, Aimaiti A, Yushan M, Alike Y, Yilihamu Y, Yusufu A
American journal of cancer research 2017;7(3):565-573
American journal of cancer research 2017;7(3):565-573
Angiopoietin-like protein 2 facilitates non-small cell lung cancer progression by promoting the polarization of M2 tumor-associated macrophages.
Wei X, Nie S, Liu H, Sun J, Liu J, Li J, Li S, Wang S, Han S, Wang J, Sun Y
American journal of cancer research 2017;7(11):2220-2233
American journal of cancer research 2017;7(11):2220-2233
Targeting NF-κB/AP-2β signaling to enhance antitumor activity of cisplatin by melatonin in hepatocellular carcinoma cells.
Hao J, Li Z, Zhang C, Yu W, Tang Z, Li Y, Feng X, Gao Y, Liu Q, Huang W, Guo W, Deng W
American journal of cancer research 2017;7(1):13-27
American journal of cancer research 2017;7(1):13-27
Exogenous H2S restores ischemic post-conditioning-induced cardioprotection through inhibiting endoplasmic reticulum stress in the aged cardiomyocytes.
Sun W, Yang J, Zhang Y, Xi Y, Wen X, Yuan D, Wang Y, Wei C, Wang R, Wu L, Li H, Xu C
Cell & bioscience 2017;7:67
Cell & bioscience 2017;7:67
Oral Administration of Lactobacillus rhamnosus GG Ameliorates Salmonella Infantis-Induced Inflammation in a Pig Model via Activation of the IL-22BP/IL-22/STAT3 Pathway.
Yang GY, Yu J, Su JH, Jiao LG, Liu X, Zhu YH
Frontiers in cellular and infection microbiology 2017;7:323
Frontiers in cellular and infection microbiology 2017;7:323
In-Cell Western Assays to Evaluate Hantaan Virus Replication as a Novel Approach to Screen Antiviral Molecules and Detect Neutralizing Antibody Titers.
Ma HW, Ye W, Chen HS, Nie TJ, Cheng LF, Zhang L, Han PJ, Wu XA, Xu ZK, Lei YF, Zhang FL
Frontiers in cellular and infection microbiology 2017;7:269
Frontiers in cellular and infection microbiology 2017;7:269
Selenomethionine Attenuates the Amyloid-β Level by Both Inhibiting Amyloid-β Production and Modulating Autophagy in Neuron-2a/AβPPswe Cells.
Zhang ZH, Wu QY, Chen C, Zheng R, Chen Y, Liu Q, Ni JZ, Song GL
Journal of Alzheimer's disease : JAD 2017;59(2):591-602
Journal of Alzheimer's disease : JAD 2017;59(2):591-602
MiR-142-5p Suppresses Tumorigenesis by Targeting PIK3CA in Non-Small Cell Lung Cancer.
Wang Z, Liu Z, Fang X, Yang H
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2017;43(6):2505-2515
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2017;43(6):2505-2515
Iridoids with Genipin Stem Nucleus Inhibit Lipopolysaccharide-Induced Inflammation and Oxidative Stress by Blocking the NF-κB Pathway in Polycystic Ovary Syndrome.
Zuo T, Zhu M, Xu W, Wang Z, Song H
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2017;43(5):1855-1865
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2017;43(5):1855-1865
The USP7 Inhibitor P5091 Induces Cell Death in Ovarian Cancers with Different P53 Status.
Wang M, Zhang Y, Wang T, Zhang J, Zhou Z, Sun Y, Wang S, Shi Y, Luan X, Zhang Y, Wang Y, Wang Y, Zou Z, Kang L, Liu H
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2017;43(5):1755-1766
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2017;43(5):1755-1766
Involvement of S100A8/A9-TLR4-NLRP3 Inflammasome Pathway in Contrast-Induced Acute Kidney Injury.
Tan X, Zheng X, Huang Z, Lin J, Xie C, Lin Y
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2017;43(1):209-222
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2017;43(1):209-222
The Lncrna-TUG1/EZH2 Axis Promotes Pancreatic Cancer Cell Proliferation, Migration and EMT Phenotype Formation Through Sponging Mir-382.
Zhao L, Sun H, Kong H, Chen Z, Chen B, Zhou M
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2017;42(6):2145-2158
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2017;42(6):2145-2158
Deoxyelephantopin Induces Reactive Oxygen Species-Mediated Apoptosis and Autophagy in Human Osteosarcoma Cells.
Zou J, Zhang Y, Sun J, Wang X, Tu H, Geng S, Liu R, Chen Y, Bi Z
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2017;42(5):1812-1821
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2017;42(5):1812-1821
CDC5L Promotes hTERT Expression and Colorectal Tumor Growth.
Li J, Zhang N, Zhang R, Sun L, Yu W, Guo W, Gao Y, Li M, Liu W, Liang P, Deng W, Cui X
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2017;41(6):2475-2488
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2017;41(6):2475-2488
SOX6 Downregulation Induces γ-Globin in Human β-Thalassemia Major Erythroid Cells.
Li J, Lai Y, Luo J, Luo L, Liu R, Liu Z, Zhao W
BioMed research international 2017;2017:9496058
BioMed research international 2017;2017:9496058
Neutrophil Extracellular Traps Are Pathogenic in Ventilator-Induced Lung Injury and Partially Dependent on TLR4.
Li H, Pan P, Su X, Liu S, Zhang L, Wu D, Li H, Dai M, Li Y, Hu C, Chen J
BioMed research international 2017;2017:8272504
BioMed research international 2017;2017:8272504
Resveratrol Prevents ROS-Induced Apoptosis in High Glucose-Treated Retinal Capillary Endothelial Cells via the Activation of AMPK/Sirt1/PGC-1α Pathway.
Li J, Yu S, Ying J, Shi T, Wang P
Oxidative medicine and cellular longevity 2017;2017:7584691
Oxidative medicine and cellular longevity 2017;2017:7584691
Differentiation of Human Amniotic Mesenchymal Stem Cells into Human Anterior Cruciate Ligament Fibroblast Cells by In Vitro Coculture.
Li Y, Liu Z, Jin Y, Zhu X, Wang S, Yang J, Ren Y, Fu Q, Xiong H, Zou G, Liu Y
BioMed research international 2017;2017:7360354
BioMed research international 2017;2017:7360354
Antidiabetic Effect of Tibetan Medicine Tang-Kang-Fu-San on High-Fat Diet and Streptozotocin-Induced Type 2 Diabetic Rats.
Duan B, Zhao Z, Lin L, Jin J, Zhang L, Xiong H, Ta N, Gao T, Mei Z
Evidence-based complementary and alternative medicine : eCAM 2017;2017:7302965
Evidence-based complementary and alternative medicine : eCAM 2017;2017:7302965
Salusin-β Is Involved in Diabetes Mellitus-Induced Endothelial Dysfunction via Degradation of Peroxisome Proliferator-Activated Receptor Gamma.
Sun HJ, Chen D, Wang PY, Wan MY, Zhang CX, Zhang ZX, Lin W, Zhang F
Oxidative medicine and cellular longevity 2017;2017:6905217
Oxidative medicine and cellular longevity 2017;2017:6905217
Electroacupuncture Alleviates Postoperative Cognitive Dysfunction in Aged Rats by Inhibiting Hippocampal Neuroinflammation Activated via Microglia/TLRs Pathway.
Feng PP, Deng P, Liu LH, Ai Q, Yin J, Liu Z, Wang GM
Evidence-based complementary and alternative medicine : eCAM 2017;2017:6421260
Evidence-based complementary and alternative medicine : eCAM 2017;2017:6421260
HIV-1 Transactivator Protein Induces ZO-1 and Neprilysin Dysfunction in Brain Endothelial Cells via the Ras Signaling Pathway.
Jiang W, Huang W, Chen Y, Zou M, Peng D, Chen D
Oxidative medicine and cellular longevity 2017;2017:3160360
Oxidative medicine and cellular longevity 2017;2017:3160360
Long-Term Effects of TCM Yangqing Kangxian Formula on Bleomycin-Induced Pulmonary Fibrosis in Rats via Regulating Nuclear Factor-κB Signaling.
Li M, Li Y, Li J, Zhao P, Bai Y, Feng S, Liu X, Wang Y, Bian Q, Li J
Evidence-based complementary and alternative medicine : eCAM 2017;2017:2089027
Evidence-based complementary and alternative medicine : eCAM 2017;2017:2089027
Synthetic Isoliquiritigenin Inhibits Human Tongue Squamous Carcinoma Cells through Its Antioxidant Mechanism.
Hou C, Li W, Li Z, Gao J, Chen Z, Zhao X, Yang Y, Zhang X, Song Y
Oxidative medicine and cellular longevity 2017;2017:1379430
Oxidative medicine and cellular longevity 2017;2017:1379430
ROR2 receptor promotes the migration of osteosarcoma cells in response to Wnt5a.
Dai B, Yan T, Zhang A
Cancer cell international 2017;17:112
Cancer cell international 2017;17:112
HSPB8 Promotes the Fusion of Autophagosome and Lysosome during Autophagy in Diabetic Neurons.
Li XC, Hu QK, Chen L, Liu SY, Su S, Tao H, Zhang LN, Sun T, He LJ
International journal of medical sciences 2017;14(13):1335-1341
International journal of medical sciences 2017;14(13):1335-1341
LncRNA AFAP1-AS Functions as a Competing Endogenous RNA to Regulate RAP1B Expression by sponging miR-181a in the HSCR.
Chen G, Peng L, Zhu Z, Du C, Shen Z, Zang R, Su Y, Xia Y, Tang W
International journal of medical sciences 2017;14(10):1022-1030
International journal of medical sciences 2017;14(10):1022-1030
Exosomes Derived from Human Pulmonary Artery Endothelial Cells Shift the Balance between Proliferation and Apoptosis of Smooth Muscle Cells.
Zhao L, Luo H, Li X, Li T, He J, Qi Q, Liu Y, Yu Z
Cardiology 2017;137(1):43-53
Cardiology 2017;137(1):43-53
Resveratrol ameliorates diet-induced dysregulation of lipid metabolism in zebrafish (Danio rerio).
Ran G, Ying L, Li L, Yan Q, Yi W, Ying C, Wu H, Ye X
PloS one 2017;12(7):e0180865
PloS one 2017;12(7):e0180865
Caveolin1 protects against diet induced hepatic lipid accumulation in mice.
Li M, Chen D, Huang H, Wang J, Wan X, Xu C, Li C, Ma H, Yu C, Li Y
PloS one 2017;12(6):e0178748
PloS one 2017;12(6):e0178748
Imatinib attenuates cardiac fibrosis by inhibiting platelet-derived growth factor receptors activation in isoproterenol induced model.
Wang LX, Yang X, Yue Y, Fan T, Hou J, Chen GX, Liang MY, Wu ZK
PloS one 2017;12(6):e0178619
PloS one 2017;12(6):e0178619
A mutation in the CACNA1C gene leads to early repolarization syndrome with incomplete penetrance: A Chinese family study.
Liu X, Shen Y, Xie J, Bao H, Cao Q, Wan R, Xu X, Zhou H, Huang L, Xu Z, Zhu W, Hu J, Cheng X, Hong K
PloS one 2017;12(5):e0177532
PloS one 2017;12(5):e0177532
Role of keratin 24 in human epidermal keratinocytes.
Min M, Chen XB, Wang P, Landeck L, Chen JQ, Li W, Cai SQ, Zheng M, Man XY
PloS one 2017;12(3):e0174626
PloS one 2017;12(3):e0174626
Far-infrared suppresses skin photoaging in ultraviolet B-exposed fibroblasts and hairless mice.
Chiu HW, Chen CH, Chen YJ, Hsu YH
PloS one 2017;12(3):e0174042
PloS one 2017;12(3):e0174042
Increased expression of protein kinase CK2α correlates with poor patient prognosis in epithelial ovarian cancer.
Ma Z, Wang X, He J, Xia J, Li Y
PloS one 2017;12(3):e0174037
PloS one 2017;12(3):e0174037
Aerobic exercise regulates Rho/cofilin pathways to rescue synaptic loss in aged rats.
Li Y, Zhao L, Gu B, Cai J, Lv Y, Yu L
PloS one 2017;12(2):e0171491
PloS one 2017;12(2):e0171491
Rottlerin as a therapeutic approach in psoriasis: Evidence from in vitro and in vivo studies.
Min M, Yan BX, Wang P, Landeck L, Chen JQ, Li W, Cai SQ, Zheng M, Man XY
PloS one 2017;12(12):e0190051
PloS one 2017;12(12):e0190051
Down-regulation of the klf5-c-Myc interaction due to klf5 phosphorylation mediates resveratrol repressing the caveolin-1 transcription through the PI3K/PKD1/Akt pathway.
Yang H, Chen Q, Sun F, Zhao N, Wen L, Li L, Ran G
PloS one 2017;12(12):e0189156
PloS one 2017;12(12):e0189156
XRCC5 cooperates with p300 to promote cyclooxygenase-2 expression and tumor growth in colon cancers.
Zhang Z, Zheng F, Yu Z, Hao J, Chen M, Yu W, Guo W, Chen Y, Huang W, Duan Z, Deng W
PloS one 2017;12(10):e0186900
PloS one 2017;12(10):e0186900
MITA/STING and Its Alternative Splicing Isoform MRP Restrict Hepatitis B Virus Replication.
Liu S, Zhao K, Su X, Lu L, Zhao H, Zhang X, Wang Y, Wu C, Chen J, Zhou Y, Hu X, Wang Y, Lu M, Chen X, Pei R
PloS one 2017;12(1):e0169701
PloS one 2017;12(1):e0169701
Gold nanoparticles attenuate metastasis by tumor vasculature normalization and epithelial-mesenchymal transition inhibition.
Li W, Li X, Liu S, Yang W, Pan F, Yang XY, Du B, Qin L, Pan Y
International journal of nanomedicine 2017;12:3509-3520
International journal of nanomedicine 2017;12:3509-3520
Knockdown of Long Non-Coding RNA KCNQ1OT1 Restrained Glioma Cells' Malignancy by Activating miR-370/CCNE2 Axis.
Gong W, Zheng J, Liu X, Liu Y, Guo J, Gao Y, Tao W, Chen J, Li Z, Ma J, Xue Y
Frontiers in cellular neuroscience 2017;11:84
Frontiers in cellular neuroscience 2017;11:84
Involvement of endoplasmic reticulum stress in formalin-induced pain is attenuated by 4-phenylbutyric acid.
Zhou F, Zhang W, Zhou J, Li M, Zhong F, Zhang Y, Liu Y, Wang Y
Journal of pain research 2017;10:653-662
Journal of pain research 2017;10:653-662
UNBS5162 inhibits proliferation of human retinoblastoma cells by promoting cell apoptosis.
Wang B, Shen J, Wang J
OncoTargets and therapy 2017;10:5303-5309
OncoTargets and therapy 2017;10:5303-5309
The Effect of MCM3AP-AS1/miR-211/KLF5/AGGF1 Axis Regulating Glioblastoma Angiogenesis.
Yang C, Zheng J, Xue Y, Yu H, Liu X, Ma J, Liu L, Wang P, Li Z, Cai H, Liu Y
Frontiers in molecular neuroscience 2017;10:437
Frontiers in molecular neuroscience 2017;10:437
Circ-104916 is downregulated in gastric cancer and suppresses migration and invasion of gastric cancer cells.
Li J, Zhen L, Zhang Y, Zhao L, Liu H, Cai D, Chen H, Yu J, Qi X, Li G
OncoTargets and therapy 2017;10:3521-3529
OncoTargets and therapy 2017;10:3521-3529
PIK3CA expression in diffuse large B cell lymphoma tissue and the effect of its knockdown in vitro.
Cui W, Zheng S, Liu Z, Wang W, Cai Y, Bi R, Cao B, Zhou X
OncoTargets and therapy 2017;10:2239-2247
OncoTargets and therapy 2017;10:2239-2247
The Role of HOTAIR/miR-148b-3p/USF1 on Regulating the Permeability of BTB.
Sa L, Li Y, Zhao L, Liu Y, Wang P, Liu L, Li Z, Ma J, Cai H, Xue Y
Frontiers in molecular neuroscience 2017;10:194
Frontiers in molecular neuroscience 2017;10:194
Downregulation of the Repressor Element 1-Silencing Transcription Factor (REST) Is Associated with Akt-mTOR and Wnt-β-Catenin Signaling in Prion Diseases Models.
Song Z, Shah SZA, Yang W, Dong H, Yang L, Zhou X, Zhao D
Frontiers in molecular neuroscience 2017;10:128
Frontiers in molecular neuroscience 2017;10:128
Tail vein injection of mmLDL upregulates mouse mesenteric artery ETB receptors via activation of the ERK1/2 pathway.
Liu Y, Chen XL, Xu CB, Cao L, Lin J, Chen G, Li J
Vascular pharmacology 2017 Sep;96-98:33-39
Vascular pharmacology 2017 Sep;96-98:33-39
Calreticulin regulates TGF-β1-induced epithelial mesenchymal transition through modulating Smad signaling and calcium signaling.
Wu Y, Xu X, Ma L, Yi Q, Sun W, Tang L
The international journal of biochemistry & cell biology 2017 Sep;90:103-113
The international journal of biochemistry & cell biology 2017 Sep;90:103-113
Ehrlichia chaffeensis TRP120 Moonlights as a HECT E3 Ligase Involved in Self- and Host Ubiquitination To Influence Protein Interactions and Stability for Intracellular Survival.
Zhu B, Das S, Mitra S, Farris TR, McBride JW
Infection and immunity 2017 Sep;85(9)
Infection and immunity 2017 Sep;85(9)
Ligustrazine modulates renal cysteine biosynthesis in rats exposed to cadmium.
Kuang W, Zhang X, Zhu W, Lan Z
Environmental toxicology and pharmacology 2017 Sep;54:125-132
Environmental toxicology and pharmacology 2017 Sep;54:125-132
The transcription factor cyclic adenosine 3',5'-monophosphate response element-binding protein enhances the odonto/osteogenic differentiation of stem cells from the apical papilla.
Su S, Zhu Y, Li S, Liang Y, Zhang J
International endodontic journal 2017 Sep;50(9):885-894
International endodontic journal 2017 Sep;50(9):885-894
lncRNA-PVT1 Facilitates Invasion Through Upregulation of MMP9 in Nonsmall Cell Lung Cancer Cell.
Chen W, Zhu H, Yin L, Wang T, Wu J, Xu J, Tao H, Liu J, He X
DNA and cell biology 2017 Sep;36(9):787-793
DNA and cell biology 2017 Sep;36(9):787-793
Stool DNA Test of Methylated Syndecan-2 for the Early Detection of Colorectal Neoplasia.
Niu F, Wen J, Fu X, Li C, Zhao R, Wu S, Yu H, Liu X, Zhao X, Liu S, Wang X, Wang J, Zou H
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2017 Sep;26(9):1411-1419
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2017 Sep;26(9):1411-1419
Vertebrate Lonesome Kinase Regulated Extracellular Matrix Protein Phosphorylation, Cell Shape, and Adhesion in Trabecular Meshwork Cells.
Maddala R, Skiba NP, Rao PV
Journal of cellular physiology 2017 Sep;232(9):2447-2460
Journal of cellular physiology 2017 Sep;232(9):2447-2460
An oligodeoxynucleotide with AAAG repeats significantly attenuates burn-induced systemic inflammatory responses via inhibiting interferon regulatory factor 5 pathway.
Xiao Y, Lu W, Li X, Zhao P, Yao Y, Wang X, Wang Y, Lin Z, Yu Y, Hua S, Wang L
Molecular medicine (Cambridge, Mass.) 2017 Sep;23:166-176
Molecular medicine (Cambridge, Mass.) 2017 Sep;23:166-176
TNF-α promotes survival and migration of MSCs under oxidative stress via NF-κB pathway to attenuate intimal hyperplasia in vein grafts.
Bai X, Xi J, Bi Y, Zhao X, Bing W, Meng X, Liu Y, Zhu Z, Song G
Journal of cellular and molecular medicine 2017 Sep;21(9):2077-2091
Journal of cellular and molecular medicine 2017 Sep;21(9):2077-2091
Assessment of tris (1, 3-dichloro-2-propyl) phosphate toxicology in PC12 cells by using digital gene expression profiling.
Li L, Jiang S, Li K, Lin B, Wang Z, Zhang Z, Fang Y
Chemosphere 2017 Sep;183:353-360
Chemosphere 2017 Sep;183:353-360
Attenuation of doxorubicin-induced cardiotoxicity by esculetin through modulation of Bmi-1 expression.
Xu F, Li X, Liu L, Xiao X, Zhang L, Zhang S, Lin P, Wang X, Wang Y, Li Q
Experimental and therapeutic medicine 2017 Sep;14(3):2216-2220
Experimental and therapeutic medicine 2017 Sep;14(3):2216-2220
Dioscin, a potent ITGA5 inhibitor, reduces the synthesis of collagen against liver fibrosis: Insights from SILAC-based proteomics analysis.
Xu L, Yin L, Tao X, Qi Y, Han X, Xu Y, Song S, Li L, Sun P, Peng J
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2017 Sep;107(Pt A):318-328
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2017 Sep;107(Pt A):318-328
Predictive single nucleotide polymorphism markers for acute oral mucositis in patients with nasopharyngeal carcinoma treated with radiotherapy.
Le Z, Niu X, Chen Y, Ou X, Zhao G, Liu Q, Tu W, Hu C, Kong L, Liu Y
Oncotarget 2017 Sep 8;8(38):63026-63037
Oncotarget 2017 Sep 8;8(38):63026-63037
Hsp90 activator Aha1 drives production of pathological tau aggregates.
Shelton LB, Baker JD, Zheng D, Sullivan LE, Solanki PK, Webster JM, Sun Z, Sabbagh JJ, Nordhues BA, Koren J 3rd, Ghosh S, Blagg BSJ, Blair LJ, Dickey CA
Proceedings of the National Academy of Sciences of the United States of America 2017 Sep 5;114(36):9707-9712
Proceedings of the National Academy of Sciences of the United States of America 2017 Sep 5;114(36):9707-9712
Sirt6 deficiency exacerbates podocyte injury and proteinuria through targeting Notch signaling.
Liu M, Liang K, Zhen J, Zhou M, Wang X, Wang Z, Wei X, Zhang Y, Sun Y, Zhou Z, Su H, Zhang C, Li N, Gao C, Peng J, Yi F
Nature communications 2017 Sep 4;8(1):413
Nature communications 2017 Sep 4;8(1):413
FAM83D, a microtubule-associated protein, promotes tumor growth and progression of human gastric cancer.
Huang M, Ma X, Shi H, Hu L, Fan Z, Pang L, Zhu F, Yang X, Xu W, Liu B, Zhu Z, Li C
Oncotarget 2017 Sep 26;8(43):74479-74493
Oncotarget 2017 Sep 26;8(43):74479-74493
Numb positively regulates autophagic flux via regulating lysosomal function.
Sun H, Liu Y, Zhang L, Shao X, Liu K, Ding Z, Liu X, Jiang C, Li H, Li H
Biochemical and biophysical research communications 2017 Sep 23;491(3):780-786
Biochemical and biophysical research communications 2017 Sep 23;491(3):780-786
Overexpression of miR-135b-5p promotes unfavorable clinical characteristics and poor prognosis via the repression of SFRP4 in pancreatic cancer.
Han X, Saiyin H, Zhao J, Fang Y, Rong Y, Shi C, Lou W, Kuang T
Oncotarget 2017 Sep 22;8(37):62195-62207
Oncotarget 2017 Sep 22;8(37):62195-62207
Regulation of the epithelial Na+ channel by paraoxonase-2.
Shi S, Buck TM, Kinlough CL, Marciszyn AL, Hughey RP, Chalfie M, Brodsky JL, Kleyman TR
The Journal of biological chemistry 2017 Sep 22;292(38):15927-15938
The Journal of biological chemistry 2017 Sep 22;292(38):15927-15938
Long non-coding RNA NEAT1 regulates epithelial membrane protein 2 expression to repress nasopharyngeal carcinoma migration and irradiation-resistance through miR-101-3p as a competing endogenous RNA mechanism.
Wang Y, Wang C, Chen C, Wu F, Shen P, Zhang P, He G, Li X
Oncotarget 2017 Sep 19;8(41):70156-70171
Oncotarget 2017 Sep 19;8(41):70156-70171
Heat-killed salmonella typhimurium (HKST) protects mice against radiation in TLR4-dependent manner.
Xu Y, Chen Y, Liu H, Lei X, Guo J, Cao K, Liu C, Li B, Cai J, Ju J, Gao F, Yang Y
Oncotarget 2017 Sep 15;8(40):67082-67093
Oncotarget 2017 Sep 15;8(40):67082-67093
Testosterone regulates 3T3-L1 pre-adipocyte differentiation and epididymal fat accumulation in mice through modulating macrophage polarization.
Ren X, Fu X, Zhang X, Chen S, Huang S, Yao L, Liu G
Biochemical pharmacology 2017 Sep 15;140:73-88
Biochemical pharmacology 2017 Sep 15;140:73-88
Cloning, expression pattern, and potential role of apoptosis inhibitor 5 in the termination of embryonic diapause and early embryo development of Artemia sinica.
Zhang S, Yao F, Jing T, Zhang M, Zhao W, Zou X, Sui L, Hou L
Gene 2017 Sep 10;628:170-179
Gene 2017 Sep 10;628:170-179
Ezrin as a possible diagnostic and/or prognostic biomarker in mice lymphatic metastatic hepatocellular carcinoma in vivo.
Bakheet AMH, Mahmoud SA, Huang Y, Zhang J, Wang J, Wei Y, Gamallat Y, Awadasseid A, Owusu L, Khidir Y, Wang L, Zhou S, Seewooruttun PK, Xin B, Xuan W, Su Z, Tang J
BioFactors (Oxford, England) 2017 Sep 10;43(5):662-672
BioFactors (Oxford, England) 2017 Sep 10;43(5):662-672
Phorbol esters dPPA/dPA promote furin expression involving transcription factor CEBPβ in neuronal cells.
Zha JS, Zhu BL, Liu L, Lai YJ, Long Y, Hu XT, Deng XJ, Wang XF, Yan Z, Chen GJ
Oncotarget 2017 Sep 1;8(36):60159-60172
Oncotarget 2017 Sep 1;8(36):60159-60172
Live-cell visualization of gasdermin D-driven pyroptotic cell death.
Rathkey JK, Benson BL, Chirieleison SM, Yang J, Xiao TS, Dubyak GR, Huang AY, Abbott DW
The Journal of biological chemistry 2017 Sep 1;292(35):14649-14658
The Journal of biological chemistry 2017 Sep 1;292(35):14649-14658
ORMDL3 Facilitates the Survival of Splenic B Cells via an ATF6α-Endoplasmic Reticulum Stress-Beclin1 Autophagy Regulatory Pathway.
Dang J, Bian X, Ma X, Li J, Long F, Shan S, Yuan Q, Xin Q, Li Y, Gao F, Gong Y, Liu Q
Journal of immunology (Baltimore, Md. : 1950) 2017 Sep 1;199(5):1647-1659
Journal of immunology (Baltimore, Md. : 1950) 2017 Sep 1;199(5):1647-1659
New Insights Into the Role of Estrogens in Male Fertility Based on Findings in Aromatase-Deficient Zebrafish.
Tang H, Chen Y, Liu Y, Yin Y, Li G, Guo Y, Liu X, Lin H
Endocrinology 2017 Sep 1;158(9):3042-3054
Endocrinology 2017 Sep 1;158(9):3042-3054
Lithium alleviates neurotoxic prion peptide-induced synaptic damage and neuronal death partially by the upregulation of nuclear target REST and the restoration of Wnt signaling.
Song Z, Yang W, Zhou X, Yang L, Zhao D
Neuropharmacology 2017 Sep 1;123:332-348
Neuropharmacology 2017 Sep 1;123:332-348
Role of Pannexin1 channels in the resistance of I-10 testicular cancer cells to cisplatin mediated by ATP/IP3 pathway.
Wu D, Wu J, Liu H, Yu M, Tao L, Dong S, Tong X
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2017 Oct;94:514-522
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2017 Oct;94:514-522
Cadmium chloride-induced testicular toxicity in male wistar rats; prophylactic effect of quercetin, and assessment of testicular recovery following cadmium chloride withdrawal.
Nna VU, Ujah GA, Mohamed M, Etim KB, Igba BO, Augustine ER, Osim EE
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2017 Oct;94:109-123
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2017 Oct;94:109-123
In vitro anticancer activities of osthole against renal cell carcinoma cells.
Liu L, Mao J, Wang Q, Zhang Z, Wu G, Tang Q, Zhao B, Li L, Li Q
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2017 Oct;94:1020-1027
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2017 Oct;94:1020-1027
Metformin Inhibits Porphyromonas gingivalis Lipopolysaccharide-Influenced Inflammatory Response in Human Gingival Fibroblasts via Regulating Activating Transcription Factor-3 Expression.
Kang W, Wang T, Hu Z, Liu F, Sun Y, Ge S
Journal of periodontology 2017 Oct;88(10):e169-e178
Journal of periodontology 2017 Oct;88(10):e169-e178
A potential contribution of dipeptidyl peptidase-4 by the mediation of monocyte differentiation in the development and progression of abdominal aortic aneurysms.
Lu HY, Huang CY, Shih CM, Lin YW, Tsai CS, Lin FY, Shih CC
Journal of vascular surgery 2017 Oct;66(4):1217-1226.e1
Journal of vascular surgery 2017 Oct;66(4):1217-1226.e1
CISD2 enhances the chemosensitivity of gastric cancer through the enhancement of 5-FU-induced apoptosis and the inhibition of autophagy by AKT/mTOR pathway.
Sun Y, Jiang Y, Huang J, Chen H, Liao Y, Yang Z
Cancer medicine 2017 Oct;6(10):2331-2346
Cancer medicine 2017 Oct;6(10):2331-2346
Propofol inhibits invasion and proliferation of C6 glioma cells by regulating the Ca2+ permeable AMPA receptor-system xc- pathway.
Wang XY, Li YL, Wang HY, Zhu M, Guo D, Wang GL, Gao YT, Yang Z, Li T, Yang CY, Chen YM
Toxicology in vitro : an international journal published in association with BIBRA 2017 Oct;44:57-65
Toxicology in vitro : an international journal published in association with BIBRA 2017 Oct;44:57-65
Trichostatin A attenuates oxidative stress-mediated myocardial injury through the FoxO3a signaling pathway.
Guo Y, Li Z, Shi C, Li J, Yao M, Chen X
International journal of molecular medicine 2017 Oct;40(4):999-1008
International journal of molecular medicine 2017 Oct;40(4):999-1008
Zinc finger protein 307 functions as a tumor‑suppressor and inhibits cell proliferation by inducing apoptosis in hepatocellular carcinoma.
Liang Y, Li Q, Chen K, Ni W, Zhan Z, Ye F, Li Y, Fang Y, Zhang F, Chen L, Ding Y
Oncology reports 2017 Oct;38(4):2229-2236
Oncology reports 2017 Oct;38(4):2229-2236
Varicella-zoster virus ORF7 interacts with ORF53 and plays a role in its trans-Golgi network localization.
Wang W, Fu W, Pan D, Cai L, Ye J, Liu J, Liu C, Que Y, Xia N, Zhu H, Cheng T
Virologica Sinica 2017 Oct;32(5):387-395
Virologica Sinica 2017 Oct;32(5):387-395
The effects of fluoride on neuronal function occurs via cytoskeleton damage and decreased signal transmission.
Chen L, Ning H, Yin Z, Song X, Feng Y, Qin H, Li Y, Wang J, Ge Y, Wang W
Chemosphere 2017 Oct;185:589-594
Chemosphere 2017 Oct;185:589-594
Proteasomal degradation of T. gondii ROP18 requires Derlin2.
Tang Y, Zheng M, An R, Chen L, Gong L, Cai H, Liu K, Yu L, Shen J, Du J
Acta tropica 2017 Oct;174:106-113
Acta tropica 2017 Oct;174:106-113
ERβ compensates for the absence of ERα function to promote osteoblast viability by inhibition of SOST signaling.
Lu S, Sun C, Miao C, Zhao Z
Experimental and therapeutic medicine 2017 Oct;14(4):3387-3392
Experimental and therapeutic medicine 2017 Oct;14(4):3387-3392
Caveolin 1-related autophagy initiated by aldosterone-induced oxidation promotes liver sinusoidal endothelial cells defenestration.
Luo X, Dan Wang, Luo X, Zhu X, Wang G, Ning Z, Li Y, Ma X, Yang R, Jin S, Huang Y, Meng Y, Li X
Redox biology 2017 Oct;13:508-521
Redox biology 2017 Oct;13:508-521
Neuroprotective Effects of Loganin on MPTP-Induced Parkinson's Disease Mice: Neurochemistry, Glial Reaction and Autophagy Studies.
Xu YD, Cui C, Sun MF, Zhu YL, Chu M, Shi YW, Lin SL, Yang XS, Shen YQ
Journal of cellular biochemistry 2017 Oct;118(10):3495-3510
Journal of cellular biochemistry 2017 Oct;118(10):3495-3510
RTN1-C mediates cerebral ischemia/reperfusion injury via ER stress and mitochondria-associated apoptosis pathways.
Gong L, Tang Y, An R, Lin M, Chen L, Du J
Cell death & disease 2017 Oct 5;8(10):e3080
Cell death & disease 2017 Oct 5;8(10):e3080
Circular RNA HIPK2 regulates astrocyte activation via cooperation of autophagy and ER stress by targeting MIR124-2HG.
Huang R, Zhang Y, Han B, Bai Y, Zhou R, Gan G, Chao J, Hu G, Yao H
Autophagy 2017 Oct 3;13(10):1722-1741
Autophagy 2017 Oct 3;13(10):1722-1741
Calreticulin promotes EGF-induced EMT in pancreatic cancer cells via Integrin/EGFR-ERK/MAPK signaling pathway.
Sheng W, Chen C, Dong M, Wang G, Zhou J, Song H, Li Y, Zhang J, Ding S
Cell death & disease 2017 Oct 26;8(10):e3147
Cell death & disease 2017 Oct 26;8(10):e3147
ANP promotes proliferation and inhibits apoptosis of ovarian granulosa cells by NPRA/PGRMC1/EGFR complex and improves ovary functions of PCOS rats.
Zheng Q, Li Y, Zhang D, Cui X, Dai K, Yang Y, Liu S, Tan J, Yan Q
Cell death & disease 2017 Oct 26;8(10):e3145
Cell death & disease 2017 Oct 26;8(10):e3145
Protective Effect of Flavonoids from Ziziphus jujuba cv. Jinsixiaozao against Acetaminophen-Induced Liver Injury by Inhibiting Oxidative Stress and Inflammation in Mice.
Huang W, Wang Y, Jiang X, Sun Y, Zhao Z, Li S
Molecules (Basel, Switzerland) 2017 Oct 20;22(10)
Molecules (Basel, Switzerland) 2017 Oct 20;22(10)
Centriolin, a centriole-appendage protein, regulates peripheral spindle migration and asymmetric division in mouse meiotic oocytes.
Sun TY, Wang HY, Kwon JW, Yuan B, Lee IW, Cui XS, Kim NH
Cell cycle (Georgetown, Tex.) 2017 Oct 2;16(19):1774-1780
Cell cycle (Georgetown, Tex.) 2017 Oct 2;16(19):1774-1780
MicroRNA-20a-mediated loss of autophagy contributes to breast tumorigenesis by promoting genomic damage and instability.
Liu L, He J, Wei X, Wan G, Lao Y, Xu W, Li Z, Hu H, Hu Z, Luo X, Wu J, Xie W, Zhang Y, Xu N
Oncogene 2017 Oct 19;36(42):5874-5884
Oncogene 2017 Oct 19;36(42):5874-5884
Linc-RoR promotes MAPK/ERK signaling and confers estrogen-independent growth of breast cancer.
Peng WX, Huang JG, Yang L, Gong AH, Mo YY
Molecular cancer 2017 Oct 17;16(1):161
Molecular cancer 2017 Oct 17;16(1):161
MicroRNA-21 suppresses ox-LDL-induced human aortic endothelial cells injuries in atherosclerosis through enhancement of autophagic flux: Involvement in promotion of lysosomal function.
Tang F, Yang TL, Zhang Z, Li XG, Zhong QQ, Zhao TT, Gong L
Experimental cell research 2017 Oct 15;359(2):374-383
Experimental cell research 2017 Oct 15;359(2):374-383
Rab11a is required for porcine reproductive and respiratory syndrome virus induced autophagy to promote viral replication.
Wang K, Li S, Worku T, Hao X, Yang L, Zhang S
Biochemical and biophysical research communications 2017 Oct 14;492(2):236-242
Biochemical and biophysical research communications 2017 Oct 14;492(2):236-242
Aneuploid Cell Survival Relies upon Sphingolipid Homeostasis.
Tang YC, Yuwen H, Wang K, Bruno PM, Bullock K, Deik A, Santaguida S, Trakala M, Pfau SJ, Zhong N, Huang T, Wang L, Clish CB, Hemann MT, Amon A
Cancer research 2017 Oct 1;77(19):5272-5286
Cancer research 2017 Oct 1;77(19):5272-5286
Far infrared promotes wound healing through activation of Notch1 signaling.
Hsu YH, Lin YF, Chen CH, Chiu YJ, Chiu HW
Journal of molecular medicine (Berlin, Germany) 2017 Nov;95(11):1203-1213
Journal of molecular medicine (Berlin, Germany) 2017 Nov;95(11):1203-1213
Role of NF-κB/GATA3 in the inhibition of lysyl oxidase by IL-1β in human amnion fibroblasts.
Zhang C, Wang W, Liu C, Lu J, Sun K
Immunology and cell biology 2017 Nov;95(10):943-952
Immunology and cell biology 2017 Nov;95(10):943-952
Long non-coding RNA HOTTIP promotes hypoxia-induced epithelial-mesenchymal transition of malignant glioma by regulating the miR-101/ZEB1 axis.
Zhang S, Wang W, Liu G, Xie S, Li Q, Li Y, Lin Z
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2017 Nov;95:711-720
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2017 Nov;95:711-720
Berberine activates caspase-9/cytochrome c-mediated apoptosis to suppress triple-negative breast cancer cells in vitro and in vivo.
Zhao Y, Jing Z, Lv J, Zhang Z, Lin J, Cao X, Zhao Z, Liu P, Mao W
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2017 Nov;95:18-24
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2017 Nov;95:18-24
Spiroplasma eriocheiris induces mouse 3T6-Swiss albino cell apoptosis that associated with the infection mechanism.
Hou L, Gu W, Zhu H, Yao W, Wang W, Meng Q
Molecular immunology 2017 Nov;91:75-85
Molecular immunology 2017 Nov;91:75-85
Effects of melatonin on the proliferation and differentiation of human dental pulp cells.
Liu Q, Fan W, He Y, Zhang F, Guan X, Deng Q, Lu X, He H, Huang F
Archives of oral biology 2017 Nov;83:33-39
Archives of oral biology 2017 Nov;83:33-39
MYC protein dysregulation is driven by BCR-PI3K signalling in diffuse large B-cell lymphoma.
Wang WG, Liu ZB, Jiang XN, Lee J, Zhou XY, Li XQ
Histopathology 2017 Nov;71(5):778-785
Histopathology 2017 Nov;71(5):778-785
Effectively enhancing cytotoxic and apoptotic effects of alpha-momorcharin by integrating a heparin-binding peptide.
Tan MJ, Cao XW, Li PF, Zhai YZ, Zhou Y, Liu YJ, Zhao J, Wang FJ
Biotechnology and applied biochemistry 2017 Nov;64(6):918-926
Biotechnology and applied biochemistry 2017 Nov;64(6):918-926
Artesunate induces apoptosis via inhibition of STAT3 in THP-1 cells.
Tan M, Rong Y, Su Q, Chen Y
Leukemia research 2017 Nov;62:98-103
Leukemia research 2017 Nov;62:98-103
MAPK/p38 regulation of cytoskeleton rearrangement accelerates induction of macrophage activation by TLR4, but not TLR3.
Bian H, Li F, Wang W, Zhao Q, Gao S, Ma J, Li X, Ren W, Qin C, Qi J
International journal of molecular medicine 2017 Nov;40(5):1495-1503
International journal of molecular medicine 2017 Nov;40(5):1495-1503
Platelet rich plasma promotes skeletal muscle cell migration in association with up-regulation of FAK, paxillin, and F-Actin formation.
Tsai WC, Yu TY, Lin LP, Lin MS, Tsai TT, Pang JS
Journal of orthopaedic research : official publication of the Orthopaedic Research Society 2017 Nov;35(11):2506-2512
Journal of orthopaedic research : official publication of the Orthopaedic Research Society 2017 Nov;35(11):2506-2512
Endothelial cell SHP-2 negatively regulates neutrophil adhesion and promotes transmigration by enhancing ICAM-1-VE-cadherin interaction.
Yan M, Zhang X, Chen A, Gu W, Liu J, Ren X, Zhang J, Wu X, Place AT, Minshall RD, Liu G
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2017 Nov;31(11):4759-4769
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2017 Nov;31(11):4759-4769
Sodium selenate activated Wnt/β-catenin signaling and repressed amyloid-β formation in a triple transgenic mouse model of Alzheimer's disease.
Jin N, Zhu H, Liang X, Huang W, Xie Q, Xiao P, Ni J, Liu Q
Experimental neurology 2017 Nov;297:36-49
Experimental neurology 2017 Nov;297:36-49
Neuroprotection of hypoxic postconditioning against global cerebral ischemia through influencing posttranslational regulations of heat shock protein 27 in adult rats.
Zhan L, Liu L, Li K, Wu B, Liu D, Liang D, Wen H, Wang Y, Sun W, Liao W, Xu E
Brain pathology (Zurich, Switzerland) 2017 Nov;27(6):822-838
Brain pathology (Zurich, Switzerland) 2017 Nov;27(6):822-838
Rho-kinase inhibitor Y-27632 facilitates the proliferation, migration and pluripotency of human periodontal ligament stem cells.
Wang T, Kang W, Du L, Ge S
Journal of cellular and molecular medicine 2017 Nov;21(11):3100-3112
Journal of cellular and molecular medicine 2017 Nov;21(11):3100-3112
Focal adhesion kinase family is involved in matrix contraction by transdifferentiated Müller cells.
Tsukahara R, Umazume K, McDonald K, Kaplan HJ, Tamiya S
Experimental eye research 2017 Nov;164:90-94
Experimental eye research 2017 Nov;164:90-94
IFNA2 p.Ala120Thr impairs the inhibitory activity of Interferon-α2 against the hepatitis B virus through altering its binding to the receptor.
Chen C, Zhu X, Xu W, Yang F, Zhang G, Wu L, Zheng Y, Gao Z, Xie C, Peng L
Antiviral research 2017 Nov;147:11-18
Antiviral research 2017 Nov;147:11-18
Reactive oxygen species-responsive polymeric nanoparticles for alleviating sepsis-induced acute liver injury in mice.
Chen G, Deng H, Song X, Lu M, Zhao L, Xia S, You G, Zhao J, Zhang Y, Dong A, Zhou H
Biomaterials 2017 Nov;144:30-41
Biomaterials 2017 Nov;144:30-41
Downregulated long non-coding RNA TCONS_00068220 upregulates apoptosis in gastric cancer cells.
Zhao Z, Xue J, Song Y, Liu T, Piao D
Oncology letters 2017 Nov;14(5):6143-6150
Oncology letters 2017 Nov;14(5):6143-6150
p63 inhibits CD44+/CD24- cell proliferation and chemoresistance in papillary thyroid carcinoma cells.
Guo JJ, Xu HS, Wu G, Ma ZY
Experimental and therapeutic medicine 2017 Nov;14(5):4693-4696
Experimental and therapeutic medicine 2017 Nov;14(5):4693-4696
Generation of apoptosis-resistant HEK293 cells with CRISPR/Cas mediated quadruple gene knockout for improved protein and virus production.
Zhang W, Xiao D, Shan L, Zhao J, Mao Q, Xia H
Biotechnology and bioengineering 2017 Nov;114(11):2539-2549
Biotechnology and bioengineering 2017 Nov;114(11):2539-2549
β-d-glucan from Antrodia Camphorata ameliorates LPS-induced inflammation and ROS production in human hepatocytes.
Chen Q, Tang H, Zha Z, Yin H, Wang Y, Wang Y, Li H, Yue L
International journal of biological macromolecules 2017 Nov;104(Pt A):768-777
International journal of biological macromolecules 2017 Nov;104(Pt A):768-777
Cell contact and pressure control of YAP localization and clustering revealed by super-resolution imaging.
Gao J, He L, Shi Y, Cai M, Xu H, Jiang J, Zhang L, Wang H
Nanoscale 2017 Nov 9;9(43):16993-17003
Nanoscale 2017 Nov 9;9(43):16993-17003
Insulin-like growth factor 2 mRNA binding protein 3 (IGF2BP3) promotes lung tumorigenesis via attenuating p53 stability.
Zhao W, Lu D, Liu L, Cai J, Zhou Y, Yang Y, Zhang Y, Zhang J
Oncotarget 2017 Nov 7;8(55):93672-93687
Oncotarget 2017 Nov 7;8(55):93672-93687
Targeted Metabolomics Reveals Abnormal Hepatic Energy Metabolism by Depletion of β-Carotene Oxygenase 2 in Mice.
Wu L, Guo X, Lyu Y, Clarke SL, Lucas EA, Smith BJ, Hildebrand D, Wang W, Medeiros DM, Shen X, Lin D
Scientific reports 2017 Nov 7;7(1):14624
Scientific reports 2017 Nov 7;7(1):14624
DC2 and KCP2 mediate the interaction between the oligosaccharyltransferase and the ER translocon.
Shrimal S, Cherepanova NA, Gilmore R
The Journal of cell biology 2017 Nov 6;216(11):3625-3638
The Journal of cell biology 2017 Nov 6;216(11):3625-3638
Curcumin inhibits bladder cancer stem cells by suppressing Sonic Hedgehog pathway.
Wang D, Kong X, Li Y, Qian W, Ma J, Wang D, Yu D, Zhong C
Biochemical and biophysical research communications 2017 Nov 4;493(1):521-527
Biochemical and biophysical research communications 2017 Nov 4;493(1):521-527
Upregulation of SOX2 activated LncRNA PVT1 expression promotes breast cancer cell growth and invasion.
Wang Y, Zhou J, Wang Z, Wang P, Li S
Biochemical and biophysical research communications 2017 Nov 4;493(1):429-436
Biochemical and biophysical research communications 2017 Nov 4;493(1):429-436
Cholecalciterol cholesterol emulsion attenuates experimental autoimmune myocarditis in mice via inhibition of the pyroptosis signaling pathway.
Liu N, Su H, Zhang Y, Liu Z, Kong J
Biochemical and biophysical research communications 2017 Nov 4;493(1):422-428
Biochemical and biophysical research communications 2017 Nov 4;493(1):422-428
Autocrine Interleukin-10 Mediates Glucagon-Like Peptide-1 Receptor-Induced Spinal Microglial β-Endorphin Expression.
Wu HY, Tang XQ, Mao XF, Wang YX
The Journal of neuroscience : the official journal of the Society for Neuroscience 2017 Nov 29;37(48):11701-11714
The Journal of neuroscience : the official journal of the Society for Neuroscience 2017 Nov 29;37(48):11701-11714
Metformin reverses bFGF-induced epithelial-mesenchymal transition in HCC cells.
Chengye W, Yu T, Ping S, Deguang S, Keyun W, Yan W, Rixin Z, Rui L, Zhenming G, Mingliang Y, Liming W
Oncotarget 2017 Nov 28;8(61):104247-104257
Oncotarget 2017 Nov 28;8(61):104247-104257
MiR-16-5p mediates a positive feedback loop in EV71-induced apoptosis and suppresses virus replication.
Zheng C, Zheng Z, Sun J, Zhang Y, Wei C, Ke X, Liu Y, Deng L, Wang H
Scientific reports 2017 Nov 27;7(1):16422
Scientific reports 2017 Nov 27;7(1):16422
Proteomics and metabolomics analysis of hepatic mitochondrial metabolism in alcohol-preferring and non-preferring rats.
Zeng HL, Yang Q, Du H, Li H, Shen Y, Liu T, Chen X, Kamal GM, Guan Q, Cheng L, Wang J, Xu F
Oncotarget 2017 Nov 24;8(60):102020-102032
Oncotarget 2017 Nov 24;8(60):102020-102032
Pim-3 as a potential predictor of chemoradiotherapy resistance in locally advanced rectal cancer patients.
Zhang RX, Zhou ZG, Lu SX, Lu ZH, Wan DS, Pan ZZ, Wu XJ, Chen G
Scientific reports 2017 Nov 22;7(1):16043
Scientific reports 2017 Nov 22;7(1):16043
AKAP95-mediated nuclear anchoring of PKA mediates cortisol-induced PTGS2 expression in human amnion fibroblasts.
Lu J, Wang W, Mi Y, Zhang C, Ying H, Wang L, Wang Y, Myatt L, Sun K
Science signaling 2017 Nov 21;10(506)
Science signaling 2017 Nov 21;10(506)
Levels of Leydig cell autophagy regulate the fertility of male naked mole-rats.
Yang W, Li L, Huang X, Kan G, Lin L, Cheng J, Xu C, Sun W, Cong W, Zhao S, Cui S
Oncotarget 2017 Nov 17;8(58):98677-98690
Oncotarget 2017 Nov 17;8(58):98677-98690
High expression of PDLIM5 facilitates cell tumorigenesis and migration by maintaining AMPK activation in prostate cancer.
Liu X, Chen L, Huang H, Lv JM, Chen M, Qu FJ, Pan XW, Li L, Yin L, Cui XG, Gao Y, Xu DF
Oncotarget 2017 Nov 17;8(58):98117-98134
Oncotarget 2017 Nov 17;8(58):98117-98134
Different miR-21-3p isoforms and their different features in colorectal cancer.
Jiao W, Leng X, Zhou Q, Wu Y, Sun L, Tan Y, Ni H, Dong X, Shen T, Liu Y, Li J
International journal of cancer 2017 Nov 15;141(10):2103-2111
International journal of cancer 2017 Nov 15;141(10):2103-2111
DLX3 promotes bone marrow mesenchymal stem cell proliferation through H19/miR-675 axis.
Zhao N, Zeng L, Liu Y, Han D, Liu H, Xu J, Jiang Y, Li C, Cai T, Feng H, Wang Y
Clinical science (London, England : 1979) 2017 Nov 15;131(22):2721-2735
Clinical science (London, England : 1979) 2017 Nov 15;131(22):2721-2735
Quercetin exerts synergetic anti-cancer activity with 10-hydroxy camptothecin.
Tang Q, Ji F, Wang J, Guo L, Li Y, Bao Y
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2017 Nov 15;109:223-232
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2017 Nov 15;109:223-232
Bcl-3 is a novel biomarker of renal fibrosis in chronic kidney disease.
Chen R, Wang L, Liu S, Chen X, Hu Y, Liu H, Zhang H, Jiang Y, Wang Q, Ye D, Li L, Liu D, Pan X, Wei L, Li X, Zhang X
Oncotarget 2017 Nov 14;8(57):97206-97216
Oncotarget 2017 Nov 14;8(57):97206-97216
FBXW8-dependent degradation of MRFAP1 in anaphase controls mitotic cell death.
Li DZ, Liu SF, Zhu L, Wang YX, Chen YX, Liu J, Hu G, Yu X, Li J, Zhang J, Wu ZX, Lu H, Liu W, Liu B
Oncotarget 2017 Nov 14;8(57):97178-97186
Oncotarget 2017 Nov 14;8(57):97178-97186
Comparative study of macrophages in naked mole rats and ICR mice.
Cheng J, Yuan Z, Yang W, Xu C, Cong W, Lin L, Zhao S, Sun W, Bai X, Cui S
Oncotarget 2017 Nov 14;8(57):96924-96934
Oncotarget 2017 Nov 14;8(57):96924-96934
iASPP Is an Antioxidative Factor and Drives Cancer Growth and Drug Resistance by Competing with Nrf2 for Keap1 Binding.
Ge W, Zhao K, Wang X, Li H, Yu M, He M, Xue X, Zhu Y, Zhang C, Cheng Y, Jiang S, Hu Y
Cancer cell 2017 Nov 13;32(5):561-573.e6
Cancer cell 2017 Nov 13;32(5):561-573.e6
CHST6 mutation screening and endoplasmatic reticulum stress in macular corneal dystrophy.
Wang L, Tang X, Lv X, Sun E, Wu D, Wang C, Liu P
Oncotarget 2017 Nov 10;8(56):96301-96312
Oncotarget 2017 Nov 10;8(56):96301-96312
KSRP specifies monocytic and granulocytic differentiation through regulating miR-129 biogenesis and RUNX1 expression.
Zhao H, Wang X, Yi P, Si Y, Tan P, He J, Yu S, Ren Y, Ma Y, Zhang J, Wang D, Wang F, Yu J
Nature communications 2017 Nov 10;8(1):1428
Nature communications 2017 Nov 10;8(1):1428
A Single-Amino-Acid Substitution at Position 225 in Hemagglutinin Alters the Transmissibility of Eurasian Avian-Like H1N1 Swine Influenza Virus in Guinea Pigs.
Wang Z, Yang H, Chen Y, Tao S, Liu L, Kong H, Ma S, Meng F, Suzuki Y, Qiao C, Chen H
Journal of virology 2017 Nov 1;91(21)
Journal of virology 2017 Nov 1;91(21)
Expression and Subcellular Localization of the Kaposi's Sarcoma-Associated Herpesvirus K15P Protein during Latency and Lytic Reactivation in Primary Effusion Lymphoma Cells.
Smith CG, Kharkwal H, Wilson DW
Journal of virology 2017 Nov 1;91(21)
Journal of virology 2017 Nov 1;91(21)
HERP Binds TBK1 To Activate Innate Immunity and Repress Virus Replication in Response to Endoplasmic Reticulum Stress.
Ge M, Luo Z, Qiao Z, Zhou Y, Cheng X, Geng Q, Cai Y, Wan P, Xiong Y, Liu F, Wu K, Liu Y, Wu J
Journal of immunology (Baltimore, Md. : 1950) 2017 Nov 1;199(9):3280-3292
Journal of immunology (Baltimore, Md. : 1950) 2017 Nov 1;199(9):3280-3292
Designed inhibitor for nuclear localization signal of polo-like kinase 1 induces mitotic arrest.
Chen F, Zhuo X, Qin T, Guo X, Zhang C, Lai L
Chemical biology & drug design 2017 May;89(5):732-740
Chemical biology & drug design 2017 May;89(5):732-740
The tumor suppressor p53 regulates autophagosomal and lysosomal biogenesis in lung cancer cells by targeting transcription factor EB.
Zhang Z, Wang H, Ding Q, Xing Y, Xu D, Xu Z, Zhou T, Qian B, Ji C, Pan X, Zhong A, Ying Z, Zhou C, Shi M
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2017 May;89:1055-1060
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2017 May;89:1055-1060
DLX3 mutation negatively regulates odontogenic differentiation of human dental pulp cells.
Zeng L, Zhao N, Han D, Liu H, Liu Y, Wang Y, Feng H
Archives of oral biology 2017 May;77:12-17
Archives of oral biology 2017 May;77:12-17
Cynandione A attenuates neuropathic pain through p38β MAPK-mediated spinal microglial expression of β-endorphin.
Huang Q, Mao XF, Wu HY, Liu H, Sun ML, Wang X, Wang YX
Brain, behavior, and immunity 2017 May;62:64-77
Brain, behavior, and immunity 2017 May;62:64-77
Involvement of FMRP in Primary MicroRNA Processing via Enhancing Drosha Translation.
Wan RP, Zhou LT, Yang HX, Zhou YT, Ye SH, Zhao QH, Gao MM, Liao WP, Yi YH, Long YS
Molecular neurobiology 2017 May;54(4):2585-2594
Molecular neurobiology 2017 May;54(4):2585-2594
The mechanism of epithelial-mesenchymal transition induced by TGF-β1 in neuroblastoma cells.
Shao JB, Gao ZM, Huang WY, Lu ZB
International journal of oncology 2017 May;50(5):1623-1633
International journal of oncology 2017 May;50(5):1623-1633
E-Prostanoid 3 Receptor Mediates Sprouting Angiogenesis Through Suppression of the Protein Kinase A/β-Catenin/Notch Pathway.
Chen D, Tang J, Wan Q, Zhang J, Wang K, Shen Y, Yu Y
Arteriosclerosis, thrombosis, and vascular biology 2017 May;37(5):856-866
Arteriosclerosis, thrombosis, and vascular biology 2017 May;37(5):856-866
Human recombinant RNASET2-induced inflammatory response and connective tissue remodeling in the medicinal leech.
Baranzini N, Pedrini E, Girardello R, Tettamanti G, de Eguileor M, Taramelli R, Acquati F, Grimaldi A
Cell and tissue research 2017 May;368(2):337-351
Cell and tissue research 2017 May;368(2):337-351
Fn14 hepatic progenitor cells are associated with liver fibrosis in biliary atresia.
Zheng L, Lv Z, Gong Z, Sheng Q, Gao Z, Zhang Y, Yu S, Zhou J, Xi Z, Wang X
Pediatric surgery international 2017 May;33(5):593-599
Pediatric surgery international 2017 May;33(5):593-599
Shen-Yuan-Dan Capsule Inhibiting Inflammatory Reaction by Regulating Insulin Receptor Substrate 1/PI3K/Akt/NF-κB Signaling Pathway in Apoliprotein E Knockout Mice Fed with a High-Fat Diet.
Zhou M, Li P, Kang Q, Zhang L, Shang J, Liu W, Liu H
Acta Cardiologica Sinica 2017 May;33(3):285-291
Acta Cardiologica Sinica 2017 May;33(3):285-291
Clinical Significance and Tumor-Suppressive Function of miR-516b in Nonsmall Cell Lung Cancer.
Zhu J, Zhang Y, Yang X, Jin L
Cancer biotherapy & radiopharmaceuticals 2017 May;32(4):115-123
Cancer biotherapy & radiopharmaceuticals 2017 May;32(4):115-123
Lethal concentration of perfluoroisobutylene induces acute lung injury in mice mediated via cytokine storm, oxidative stress and apoptosis.
Zhang Y, Fan L, Xi R, Mao Z, Shi D, Ding D, Zhang Z, Wang X
Inhalation toxicology 2017 May;29(6):255-265
Inhalation toxicology 2017 May;29(6):255-265
BNIP3 promotes the motility and migration of keratinocyte under hypoxia.
Zhang J, Zhang D, Yan T, Jiang X, Zhang C, Zhao L, Li L, Tang D, Zhang Q, Jia J, Zhang J, Huang Y
Experimental dermatology 2017 May;26(5):416-422
Experimental dermatology 2017 May;26(5):416-422
TSA protects H9c2 cells against thapsigargin-induced apoptosis related to endoplasmic reticulum stress-mediated mitochondrial injury.
Li Z, Liu Y, Dai X, Zhou Q, Liu X, Li Z, Chen X
Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society 2017 May;25(4):595-600
Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society 2017 May;25(4):595-600
lncRNA-HIT promotes cell proliferation of non-small cell lung cancer by association with E2F1.
Yu L, Fang F, Lu S, Li X, Yang Y, Wang Z
Cancer gene therapy 2017 May;24(5):221-226
Cancer gene therapy 2017 May;24(5):221-226
EphrinB-EphB Signaling Induces Hyperalgesia through ERK5/CREB Pathway in Rats.
Yu LN, Sun LH, Wang M, Wang LJ, Wu Y, Yu J, Wang WN, Zhang FJ, Li X, Yan M
Pain physician 2017 May;20(4):E563-E574
Pain physician 2017 May;20(4):E563-E574
siRNA-mediated knockdown of ID1 disrupts Nanog- and Oct-4-mediated cancer stem cell-likeness and resistance to chemotherapy in gastric cancer cells.
Li L, Wei X, Wu B, Xiao Y, Yin M, Yang Q
Oncology letters 2017 May;13(5):3014-3024
Oncology letters 2017 May;13(5):3014-3024
PCSK9 regulates apoptosis in human lung adenocarcinoma A549 cells via endoplasmic reticulum stress and mitochondrial signaling pathways.
Xu X, Cui Y, Cao L, Zhang Y, Yin Y, Hu X
Experimental and therapeutic medicine 2017 May;13(5):1993-1999
Experimental and therapeutic medicine 2017 May;13(5):1993-1999
Dihydroartemisin inhibits glioma invasiveness via a ROS to P53 to β-catenin signaling.
Que Z, Wang P, Hu Y, Xue Y, Liu X, Qu C, Ma J, Liu Y
Pharmacological research 2017 May;119:72-88
Pharmacological research 2017 May;119:72-88
Galectin-3 mediates the pulmonary arterial hypertension-induced right ventricular remodeling through interacting with NADPH oxidase 4.
He J, Li X, Luo H, Li T, Zhao L, Qi Q, Liu Y, Yu Z
Journal of the American Society of Hypertension : JASH 2017 May;11(5):275-289.e2
Journal of the American Society of Hypertension : JASH 2017 May;11(5):275-289.e2
A novel inducible lentiviral system for multi-gene expression with human HSP70 promoter and tetracycline-induced promoter.
Li S, Ma L, Ou M, Feng J, Liao Y, Wang G, Tang L
Applied microbiology and biotechnology 2017 May;101(9):3689-3702
Applied microbiology and biotechnology 2017 May;101(9):3689-3702
Upregulation of the lncRNA Meg3 induces autophagy to inhibit tumorigenesis and progression of epithelial ovarian carcinoma by regulating activity of ATG3.
Xiu YL, Sun KX, Chen X, Chen S, Zhao Y, Guo QG, Zong ZH
Oncotarget 2017 May 9;8(19):31714-31725
Oncotarget 2017 May 9;8(19):31714-31725
Atgl gene deletion predisposes to proximal tubule damage by impairing the fatty acid metabolism.
Chen W, Zhang Q, Cheng S, Huang J, Diao G, Han J
Biochemical and biophysical research communications 2017 May 20;487(1):160-166
Biochemical and biophysical research communications 2017 May 20;487(1):160-166
miR-29a regulated ER-positive breast cancer cell growth and invasion and is involved in the insulin signaling pathway.
Li ZH, Xiong QY, Xu L, Duan P, Yang QO, Zhou P, Tu JH
Oncotarget 2017 May 16;8(20):32566-32575
Oncotarget 2017 May 16;8(20):32566-32575
Fatty acid synthesis is critical for stem cell pluripotency via promoting mitochondrial fission.
Wang L, Zhang T, Wang L, Cai Y, Zhong X, He X, Hu L, Tian S, Wu M, Hui L, Zhang H, Gao P
The EMBO journal 2017 May 15;36(10):1330-1347
The EMBO journal 2017 May 15;36(10):1330-1347
MiR-23a-5p modulates mycobacterial survival and autophagy during mycobacterium tuberculosis infection through TLR2/MyD88/NF-κB pathway by targeting TLR2.
Gu X, Gao Y, Mu DG, Fu EQ
Experimental cell research 2017 May 15;354(2):71-77
Experimental cell research 2017 May 15;354(2):71-77
Identification and activation of TLR4-mediated signalling pathways by alginate-derived guluronate oligosaccharide in RAW264.7 macrophages.
Fang W, Bi D, Zheng R, Cai N, Xu H, Zhou R, Lu J, Wan M, Xu X
Scientific reports 2017 May 10;7(1):1663
Scientific reports 2017 May 10;7(1):1663
CRISPR/Cas9 Screens Reveal Epstein-Barr Virus-Transformed B Cell Host Dependency Factors.
Ma Y, Walsh MJ, Bernhardt K, Ashbaugh CW, Trudeau SJ, Ashbaugh IY, Jiang S, Jiang C, Zhao B, Root DE, Doench JG, Gewurz BE
Cell host & microbe 2017 May 10;21(5):580-591.e7
Cell host & microbe 2017 May 10;21(5):580-591.e7
Chromium contributes to human bronchial epithelial cell carcinogenesis by activating Gli2 and inhibiting autophagy.
Huang J, Wu G, Zeng R, Wang J, Cai R, Ho JC, Zhang J, Zheng Y
Toxicology research 2017 May 1;6(3):324-332
Toxicology research 2017 May 1;6(3):324-332
7-O-Geranylquercetin induces apoptosis in gastric cancer cells via ROS-MAPK mediated mitochondrial signaling pathway activation.
Zhu Y, Jiang Y, Shi L, Du L, Xu X, Wang E, Sun Y, Guo X, Zou B, Wang H, Wang C, Sun L, Zhen Y
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2017 Mar;87:527-538
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2017 Mar;87:527-538
Vascular endothelial cells senescence is associated with NOD-like receptor family pyrin domain-containing 3 (NLRP3) inflammasome activation via reactive oxygen species (ROS)/thioredoxin-interacting protein (TXNIP) pathway.
Yin Y, Zhou Z, Liu W, Chang Q, Sun G, Dai Y
The international journal of biochemistry & cell biology 2017 Mar;84:22-34
The international journal of biochemistry & cell biology 2017 Mar;84:22-34
Melatonin synergizes the chemotherapeutic effect of 5-fluorouracil in colon cancer by suppressing PI3K/AKT and NF-κB/iNOS signaling pathways.
Gao Y, Xiao X, Zhang C, Yu W, Guo W, Zhang Z, Li Z, Feng X, Hao J, Zhang K, Xiao B, Chen M, Huang W, Xiong S, Wu X, Deng W
Journal of pineal research 2017 Mar;62(2)
Journal of pineal research 2017 Mar;62(2)
Hepatic deletion of X-box binding protein 1 impairs bile acid metabolism in mice.
Liu X, Henkel AS, LeCuyer BE, Hubchak SC, Schipma MJ, Zhang E, Green RM
Journal of lipid research 2017 Mar;58(3):504-511
Journal of lipid research 2017 Mar;58(3):504-511
PBDE-209 exposure damages learning and memory ability in rats potentially through increased autophagy and apoptosis in the hippocampus neuron.
Sun W, Du L, Tang W, Kuang L, Du P, Chen J, Chen D
Environmental toxicology and pharmacology 2017 Mar;50:151-158
Environmental toxicology and pharmacology 2017 Mar;50:151-158
miR-194 functions as a novel modulator of cellular senescence in mouse embryonic fibroblasts.
Xu S, Zhang B, Zhu Y, Huang H, Yang W, Huang H, Zheng HL, Liu X
Cell biology international 2017 Mar;41(3):249-257
Cell biology international 2017 Mar;41(3):249-257
High mobility group box 1/toll-like receptor 4/myeloid differentiation factor 88 signaling promotes progression of gastric cancer.
Yue Y, Zhou T, Gao Y, Zhang Z, Li L, Liu L, Shi W, Su L, Cheng B
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2017 Mar;39(3):1010428317694312
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2017 Mar;39(3):1010428317694312
MicroRNA-133b is regulated by TAp63 while no gene mutation is present in colorectal cancer.
Chen Y, Zhang Y, He J, Fu Y, Lin C, Li X
Oncology reports 2017 Mar;37(3):1646-1652
Oncology reports 2017 Mar;37(3):1646-1652
Knockdown of NUPR1 inhibits the proliferation of glioblastoma cells via ERK1/2, p38 MAPK and caspase-3.
Li J, Ren S, Liu Y, Lian Z, Dong B, Yao Y, Xu Y
Journal of neuro-oncology 2017 Mar;132(1):15-26
Journal of neuro-oncology 2017 Mar;132(1):15-26
Conditional knockout of Fgf13 in murine hearts increases arrhythmia susceptibility and reveals novel ion channel modulatory roles.
Wang X, Tang H, Wei EQ, Wang Z, Yang J, Yang R, Wang S, Zhang Y, Pitt GS, Zhang H, Wang C
Journal of molecular and cellular cardiology 2017 Mar;104:63-74
Journal of molecular and cellular cardiology 2017 Mar;104:63-74
Epidermal CD147 expression plays a key role in IL-22-induced psoriatic dermatitis.
Peng C, Zhang S, Lei L, Zhang X, Jia X, Luo Z, Huang X, Kuang Y, Zeng W, Su J, Chen X
Scientific reports 2017 Mar 8;7:44172
Scientific reports 2017 Mar 8;7:44172
A 3 base pair deletion in TBX1 leads to reduced protein expression and transcriptional activity.
Xu Y, Fang S, Zhang E, Pu T, Cao R, Fu Q, Li F, Chen S, Sun K, Xu R
Scientific reports 2017 Mar 8;7:44165
Scientific reports 2017 Mar 8;7:44165
Neuroprotective effects of lycopene in spinal cord injury in rats via antioxidative and anti-apoptotic pathway.
Hu W, Wang H, Liu Z, Liu Y, Wang R, Luo X, Huang Y
Neuroscience letters 2017 Mar 6;642:107-112
Neuroscience letters 2017 Mar 6;642:107-112
Dectin-2 Deficiency Modulates Th1 Differentiation and Improves Wound Healing After Myocardial Infarction.
Yan X, Zhang H, Fan Q, Hu J, Tao R, Chen Q, Iwakura Y, Shen W, Lu L, Zhang Q, Zhang R
Circulation research 2017 Mar 31;120(7):1116-1129
Circulation research 2017 Mar 31;120(7):1116-1129
Transducin (β)-like 1 X-linked receptor 1 promotes gastric cancer progression via the ERK1/2 pathway.
Zhou Q, Wang X, Yu Z, Wu X, Chen X, Li J, Zhu Z, Liu B, Su L
Oncogene 2017 Mar 30;36(13):1873-1886
Oncogene 2017 Mar 30;36(13):1873-1886
IL-6 secreted by cancer-associated fibroblasts promotes epithelial-mesenchymal transition and metastasis of gastric cancer via JAK2/STAT3 signaling pathway.
Wu X, Tao P, Zhou Q, Li J, Yu Z, Wang X, Li J, Li C, Yan M, Zhu Z, Liu B, Su L
Oncotarget 2017 Mar 28;8(13):20741-20750
Oncotarget 2017 Mar 28;8(13):20741-20750
Nuclear localization of Beclin 1 promotes radiation-induced DNA damage repair independent of autophagy.
Xu F, Fang Y, Yan L, Xu L, Zhang S, Cao Y, Xu L, Zhang X, Xie J, Jiang G, Ge C, An N, Zhou D, Yuan N, Wang J
Scientific reports 2017 Mar 27;7:45385
Scientific reports 2017 Mar 27;7:45385
Anti-tumor effect of evodiamine by inducing Akt-mediated apoptosis in hepatocellular carcinoma.
Yang F, Shi L, Liang T, Ji L, Zhang G, Shen Y, Zhu F, Xu L
Biochemical and biophysical research communications 2017 Mar 25;485(1):54-61
Biochemical and biophysical research communications 2017 Mar 25;485(1):54-61
PPARβ/δ, a Novel Regulator for Vascular Smooth Muscle Cells Phenotypic Modulation and Vascular Remodeling after Subarachnoid Hemorrhage in Rats.
Zhang H, Jiang L, Guo Z, Zhong J, Wu J, He J, Liu H, He Z, Wu H, Cheng C, Sun X
Scientific reports 2017 Mar 22;7:45234
Scientific reports 2017 Mar 22;7:45234
Molecular signaling underlying bulleyaconitine A (BAA)-induced microglial expression of prodynorphin.
Li TF, Wu HY, Wang YR, Li XY, Wang YX
Scientific reports 2017 Mar 22;7:45056
Scientific reports 2017 Mar 22;7:45056
Whole-exome sequencing identified a homozygous BRDT mutation in a patient with acephalic spermatozoa.
Li L, Sha Y, Wang X, Li P, Wang J, Kee K, Wang B
Oncotarget 2017 Mar 21;8(12):19914-19922
Oncotarget 2017 Mar 21;8(12):19914-19922
The promotion of the transformation of quiescent gastric cancer stem cells by IL-17 and the underlying mechanisms.
Jiang YX, Yang SW, Li PA, Luo X, Li ZY, Hao YX, Yu PW
Oncogene 2017 Mar 2;36(9):1256-1264
Oncogene 2017 Mar 2;36(9):1256-1264
Combined transplantation of human mesenchymal stem cells and human retinal progenitor cells into the subretinal space of RCS rats.
Qu L, Gao L, Xu H, Duan P, Zeng Y, Liu Y, Yin ZQ
Scientific reports 2017 Mar 15;7(1):199
Scientific reports 2017 Mar 15;7(1):199
Cytoskeleton-associated protein 5 and clathrin heavy chain binding regulates spindle assembly in mouse oocytes.
Lu A, Zhou CJ, Wang DH, Han Z, Kong XW, Ma YZ, Yun ZZ, Liang CG
Oncotarget 2017 Mar 14;8(11):17491-17503
Oncotarget 2017 Mar 14;8(11):17491-17503
Nonstructural Protein 4 of Porcine Reproductive and Respiratory Syndrome Virus Modulates Cell Surface Swine Leukocyte Antigen Class I Expression by Downregulating β2-Microglobulin Transcription.
Qi P, Liu K, Wei J, Li Y, Li B, Shao D, Wu Z, Shi Y, Tong G, Qiu Y, Ma Z
Journal of virology 2017 Mar 1;91(5)
Journal of virology 2017 Mar 1;91(5)
Selenomethionine Mitigates Cognitive Decline by Targeting Both Tau Hyperphosphorylation and Autophagic Clearance in an Alzheimer's Disease Mouse Model.
Zhang ZH, Wu QY, Zheng R, Chen C, Chen Y, Liu Q, Hoffmann PR, Ni JZ, Song GL
The Journal of neuroscience : the official journal of the Society for Neuroscience 2017 Mar 1;37(9):2449-2462
The Journal of neuroscience : the official journal of the Society for Neuroscience 2017 Mar 1;37(9):2449-2462
The MLKL Channel in Necroptosis Is an Octamer Formed by Tetramers in a Dyadic Process.
Huang D, Zheng X, Wang ZA, Chen X, He WT, Zhang Y, Xu JG, Zhao H, Shi W, Wang X, Zhu Y, Han J
Molecular and cellular biology 2017 Mar 1;37(5)
Molecular and cellular biology 2017 Mar 1;37(5)
miR-137 downregulates c-kit expression in acute myeloid leukemia.
Hu Y, Dong X, Chu G, Lai G, Zhang B, Wang L, Zhao Y
Leukemia research 2017 Jun;57:72-77
Leukemia research 2017 Jun;57:72-77
miR-19 targeting of GSK3β mediates sulforaphane suppression of lung cancer stem cells.
Zhu J, Wang S, Chen Y, Li X, Jiang Y, Yang X, Li Y, Wang X, Meng Y, Zhu M, Ma X, Huang C, Wu R, Xie C, Geng S, Wu J, Zhong C, Han H
The Journal of nutritional biochemistry 2017 Jun;44:80-91
The Journal of nutritional biochemistry 2017 Jun;44:80-91
Cr(VI) induces cytotoxicity in vitro through activation of ROS-mediated endoplasmic reticulum stress and mitochondrial dysfunction via the PI3K/Akt signaling pathway.
Zhang Y, Xiao F, Liu X, Liu K, Zhou X, Zhong C
Toxicology in vitro : an international journal published in association with BIBRA 2017 Jun;41:232-244
Toxicology in vitro : an international journal published in association with BIBRA 2017 Jun;41:232-244
Simvastatin Inhibits IL-1β-Induced Apoptosis and Extracellular Matrix Degradation by Suppressing the NF-kB and MAPK Pathways in Nucleus Pulposus Cells.
Tu J, Li W, Zhang Y, Wu X, Song Y, Kang L, Liu W, Wang K, Li S, Hua W, Yang C
Inflammation 2017 Jun;40(3):725-734
Inflammation 2017 Jun;40(3):725-734
Apobec-1 complementation factor regulates cell migration and apoptosis through Dickkopf1 by acting on its 3' untranslated region in MCF7 cells.
Yan X, Li Q, Ni D, Xie Y, He Q, Wan Q, Liu Y, Lyu Z, Mao Z, Zhou Q
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2017 Jun;39(6):1010428317706218
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2017 Jun;39(6):1010428317706218
RON and c-Met facilitate metastasis through the ERK signaling pathway in prostate cancer cells.
Yin B, Liu Z, Wang Y, Wang X, Liu W, Yu P, Duan X, Liu C, Chen Y, Zhang Y, Pan X, Yao H, Liao Z, Tao Z
Oncology reports 2017 Jun;37(6):3209-3218
Oncology reports 2017 Jun;37(6):3209-3218
Cooperation of Musashi-2, Numb, MDM2, and P53 in drug resistance and malignant biology of pancreatic cancer.
Sheng W, Dong M, Chen C, Wang Z, Li Y, Wang K, Li Y, Zhou J
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2017 Jun;31(6):2429-2438
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2017 Jun;31(6):2429-2438
Role of the Wnt/β-catenin signaling pathway in inducing apoptosis and renal fibrosis in 5/6-nephrectomized rats.
Lin X, Zha Y, Zeng XZ, Dong R, Wang QH, Wang DT
Molecular medicine reports 2017 Jun;15(6):3575-3582
Molecular medicine reports 2017 Jun;15(6):3575-3582
Overexpressed miR-9 promotes tumor metastasis via targeting E-cadherin in serous ovarian cancer.
Zhou B, Xu H, Xia M, Sun C, Li N, Guo E, Guo L, Shan W, Lu H, Wu Y, Li Y, Yang D, Weng D, Meng L, Hu J, Ma D, Chen G, Li K
Frontiers of medicine 2017 Jun;11(2):214-222
Frontiers of medicine 2017 Jun;11(2):214-222
Nucleotide-binding oligomerization domain (NOD) signaling defects and cell death susceptibility cannot be uncoupled in X-linked inhibitor of apoptosis (XIAP)-driven inflammatory disease.
Chirieleison SM, Marsh RA, Kumar P, Rathkey JK, Dubyak GR, Abbott DW
The Journal of biological chemistry 2017 Jun 9;292(23):9666-9679
The Journal of biological chemistry 2017 Jun 9;292(23):9666-9679
Loss of the novel mitochondrial protein FAM210B promotes metastasis via PDK4-dependent metabolic reprogramming.
Sun S, Liu J, Zhao M, Han Y, Chen P, Mo Q, Wang B, Chen G, Fang Y, Tian Y, Zhou J, Ma D, Gao Q, Wu P
Cell death & disease 2017 Jun 8;8(6):e2870
Cell death & disease 2017 Jun 8;8(6):e2870
Upconversion nanoparticle-mediated photodynamic therapy induces autophagy and cholesterol efflux of macrophage-derived foam cells via ROS generation.
Han XB, Li HX, Jiang YQ, Wang H, Li XS, Kou JY, Zheng YH, Liu ZN, Li H, Li J, Dou D, Wang Y, Tian Y, Yang LM
Cell death & disease 2017 Jun 8;8(6):e2864
Cell death & disease 2017 Jun 8;8(6):e2864
Erythropoietin activates SIRT1 to protect human cardiomyocytes against doxorubicin-induced mitochondrial dysfunction and toxicity.
Cui L, Guo J, Zhang Q, Yin J, Li J, Zhou W, Zhang T, Yuan H, Zhao J, Zhang L, Carmichael PL, Peng S
Toxicology letters 2017 Jun 5;275:28-38
Toxicology letters 2017 Jun 5;275:28-38
(-)-Epigallocatechin-3-Gallate Inhibits Colorectal Cancer Stem Cells by Suppressing Wnt/β-Catenin Pathway.
Chen Y, Wang XQ, Zhang Q, Zhu JY, Li Y, Xie CF, Li XT, Wu JS, Geng SS, Zhong CY, Han HY
Nutrients 2017 Jun 3;9(6)
Nutrients 2017 Jun 3;9(6)
miR-181d/MALT1 regulatory axis attenuates mesenchymal phenotype through NF-κB pathways in glioblastoma.
Yang F, Liu X, Liu Y, Liu Y, Zhang C, Wang Z, Jiang T, Wang Y
Cancer letters 2017 Jun 28;396:1-9
Cancer letters 2017 Jun 28;396:1-9
AQP9-induced cell cycle arrest is associated with RAS activation and improves chemotherapy treatment efficacy in colorectal cancer.
Huang D, Feng X, Liu Y, Deng Y, Chen H, Chen D, Fang L, Cai Y, Liu H, Wang L, Wang J, Yang Z
Cell death & disease 2017 Jun 22;8(6):e2894
Cell death & disease 2017 Jun 22;8(6):e2894
Total Flavonoids of Drynariae Rhizoma Prevent Bone Loss Induced by Hindlimb Unloading in Rats.
Song S, Gao Z, Lei X, Niu Y, Zhang Y, Li C, Lu Y, Wang Z, Shang P
Molecules (Basel, Switzerland) 2017 Jun 22;22(7)
Molecules (Basel, Switzerland) 2017 Jun 22;22(7)
Chemokine receptor CXCR4 regulates CaMKII/CREB pathway in spinal neurons that underlies cancer-induced bone pain.
Hu XM, Zhang H, Xu H, Zhang HL, Chen LP, Cui WQ, Yang W, Shen W
Scientific reports 2017 Jun 21;7(1):4005
Scientific reports 2017 Jun 21;7(1):4005
Long-Term Dietary Supplementation with Selenium-Enriched Yeast Improves Cognitive Impairment, Reverses Synaptic Deficits, and Mitigates Tau Pathology in a Triple Transgenic Mouse Model of Alzheimer's Disease.
Zhang ZH, Wen L, Wu QY, Chen C, Zheng R, Liu Q, Ni JZ, Song GL
Journal of agricultural and food chemistry 2017 Jun 21;65(24):4970-4979
Journal of agricultural and food chemistry 2017 Jun 21;65(24):4970-4979
Expression of estrogen receptors and androgen receptor and their clinical significance in gastric cancer.
Tang W, Liu R, Yan Y, Pan X, Wang M, Han X, Ren H, Zhang Z
Oncotarget 2017 Jun 20;8(25):40765-40777
Oncotarget 2017 Jun 20;8(25):40765-40777
Clonorchis sinensis lysophospholipase A upregulates IL-25 expression in macrophages as a potential pathway to liver fibrosis.
Zhou L, Shi M, Zhao L, Lin Z, Tang Z, Sun H, Chen T, Lv Z, Xu J, Huang Y, Yu X
Parasites & vectors 2017 Jun 17;10(1):295
Parasites & vectors 2017 Jun 17;10(1):295
RUFY3 interaction with FOXK1 promotes invasion and metastasis in colorectal cancer.
Xie R, Wang J, Liu X, Wu L, Zhang H, Tang W, Li Y, Xiang L, Peng Y, Huang X, Bai Y, Liu G, Li A, Wang Y, Chen Y, Ren Y, Li G, Gong W, Liu S, Wang J
Scientific reports 2017 Jun 16;7(1):3709
Scientific reports 2017 Jun 16;7(1):3709
CDK4 protein is degraded by anaphase-promoting complex/cyclosome in mitosis and reaccumulates in early G1 phase to initiate a new cell cycle in HeLa cells.
Chen H, Xu X, Wang G, Zhang B, Wang G, Xin G, Liu J, Jiang Q, Zhang H, Zhang C
The Journal of biological chemistry 2017 Jun 16;292(24):10131-10141
The Journal of biological chemistry 2017 Jun 16;292(24):10131-10141
Quantitative Proteomic Analysis of Mosquito C6/36 Cells Reveals Host Proteins Involved in Zika Virus Infection.
Xin QL, Deng CL, Chen X, Wang J, Wang SB, Wang W, Deng F, Zhang B, Xiao G, Zhang LK
Journal of virology 2017 Jun 15;91(12)
Journal of virology 2017 Jun 15;91(12)
BST2 confers cisplatin resistance via NF-κB signaling in nasopharyngeal cancer.
Kuang CM, Fu X, Hua YJ, Shuai WD, Ye ZH, Li Y, Peng QH, Li YZ, Chen S, Qian CN, Huang W, Liu RY
Cell death & disease 2017 Jun 15;8(6):e2874
Cell death & disease 2017 Jun 15;8(6):e2874
The phosphatase Pgam5 antagonizes Wnt/β-Catenin signaling in embryonic anterior-posterior axis patterning.
Rauschenberger V, Bernkopf DB, Krenn S, Jalal K, Heller J, Behrens J, Gentzel M, Schambony A
Development (Cambridge, England) 2017 Jun 15;144(12):2234-2247
Development (Cambridge, England) 2017 Jun 15;144(12):2234-2247
Promoting tumorigenesis in nasopharyngeal carcinoma, NEDD8 serves as a potential theranostic target.
Xie P, Yang JP, Cao Y, Peng LX, Zheng LS, Sun R, Meng DF, Wang MY, Mei Y, Qiang YY, Cao L, Xiang YQ, Luo DH, Yun JP, Huang BJ, Jia LJ, Qian CN
Cell death & disease 2017 Jun 1;8(6):e2834
Cell death & disease 2017 Jun 1;8(6):e2834
cMyBP-C was decreased via KLHL3-mediated proteasomal degradation in congenital heart diseases.
Wang L, Lai G, Chu G, Liang X, Zhao Y
Experimental cell research 2017 Jun 1;355(1):18-25
Experimental cell research 2017 Jun 1;355(1):18-25
Wogonin mitigates nonalcoholic fatty liver disease via enhancing PPARα/AdipoR2, in vivo and in vitro.
Chen J, Liu J, Wang Y, Hu X, Zhou F, Hu Y, Yuan Y, Xu Y
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2017 Jul;91:621-631
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2017 Jul;91:621-631
Garlic-derived organosulfur compound exerts antitumor efficacy via activation of MAPK pathway and modulation of cytokines in SGC-7901 tumor-bearing mice.
Jiang X, Zhu X, Huang W, Xu H, Zhao Z, Li S, Li S, Cai J, Cao J
International immunopharmacology 2017 Jul;48:135-145
International immunopharmacology 2017 Jul;48:135-145
Timing of autophagy and apoptosis during posterior silk gland degeneration in Bombyx mori.
Montali A, Romanelli D, Cappellozza S, Grimaldi A, de Eguileor M, Tettamanti G
Arthropod structure & development 2017 Jul;46(4):518-528
Arthropod structure & development 2017 Jul;46(4):518-528
RUVBL1-ITFG1 interaction is required for collective invasion in breast cancer.
Fan W, Xie J, Xia J, Zhang Y, Yang M, Wang H, Pan Y, Zhang M, Han B, Wu B, Hou Z, Liang D, Wang C, Xu J, Song L, Liu Q
Biochimica et biophysica acta. General subjects 2017 Jul;1861(7):1788-1800
Biochimica et biophysica acta. General subjects 2017 Jul;1861(7):1788-1800
Correlation study of DNA methylation of WNT6 gene with osteosarcoma in children.
Li L, Xu C, Liu P, Huang J
Oncology letters 2017 Jul;14(1):271-275
Oncology letters 2017 Jul;14(1):271-275
Bacterial effector NleL promotes enterohemorrhagic E. coli-induced attaching and effacing lesions by ubiquitylating and inactivating JNK.
Sheng X, You Q, Zhu H, Chang Z, Li Q, Wang H, Wang C, Wang H, Hui L, Du C, Xie X, Zeng R, Lin A, Shi D, Ruan K, Yan J, Gao GF, Shao F, Hu R
PLoS pathogens 2017 Jul;13(7):e1006534
PLoS pathogens 2017 Jul;13(7):e1006534
USP19 suppresses cellular type I interferon signaling by targeting TRAF3 for deubiquitination.
Gu Z, Shi W, Zhang L, Hu Z, Xu C
Future microbiology 2017 Jul;12:767-779
Future microbiology 2017 Jul;12:767-779
Cigarette smoke extract induces EGFR-TKI resistance via promoting EGFR signaling pathway and ROS generation in NSCLC cell lines.
Zhang L, Li J, Hu J, Li D, Wang X, Zhang R, Zhang H, Shi M, Chen H
Lung cancer (Amsterdam, Netherlands) 2017 Jul;109:109-116
Lung cancer (Amsterdam, Netherlands) 2017 Jul;109:109-116
5T4-specific chimeric antigen receptor modification promotes the immune efficacy of cytokine-induced killer cells against nasopharyngeal carcinoma stem cell-like cells.
Guo X, Zheng H, Luo W, Zhang Q, Liu J, Yao K
Scientific reports 2017 Jul 7;7(1):4859
Scientific reports 2017 Jul 7;7(1):4859
SNORD47, a box C/D snoRNA, suppresses tumorigenesis in glioblastoma.
Xu B, Ye MH, Lv SG, Wang QX, Wu MJ, Xiao B, Kang CS, Zhu XG
Oncotarget 2017 Jul 4;8(27):43953-43966
Oncotarget 2017 Jul 4;8(27):43953-43966
Down-regulation of UBC9 increases the sensitivity of hepatocellular carcinoma to doxorubicin.
Fang S, Qiu J, Wu Z, Bai T, Guo W
Oncotarget 2017 Jul 25;8(30):49783-49795
Oncotarget 2017 Jul 25;8(30):49783-49795
Fork Head Box Class O1 (FOXO1) Activates Bim Expression to Mediate Cardiac Apoptosis in Chronic Intermittent Hypoxia-Induced Cardiac Hypertrophy.
Li G, Jin M, He Y, Ren J, Zhang M, Chen Y, Lan X, Zhong J, Liu H
Medical science monitor : international medical journal of experimental and clinical research 2017 Jul 24;23:3603-3616
Medical science monitor : international medical journal of experimental and clinical research 2017 Jul 24;23:3603-3616
Correction: Phosphoglycerate mutase 1 regulates dNTP pool and promotes homologous recombination repair in cancer cells.
Qu J, Sun W, Zhong J, Lv H, Zhu M, Xu J, Jin N, Xie Z, Tan M, Lin SH, Geng M, Ding J, Huang M
The Journal of cell biology 2017 Jul 24;
The Journal of cell biology 2017 Jul 24;
Autophagosome maturation mediated by Rab7 contributes to neuroprotection of hypoxic preconditioning against global cerebral ischemia in rats.
Zhan L, Chen S, Li K, Liang D, Zhu X, Liu L, Lu Z, Sun W, Xu E
Cell death & disease 2017 Jul 20;8(7):e2949
Cell death & disease 2017 Jul 20;8(7):e2949
FOXQ1 regulates senescence-associated inflammation via activation of SIRT1 expression.
Wang P, Lv C, Zhang T, Liu J, Yang J, Guan F, Hong T
Cell death & disease 2017 Jul 20;8(7):e2946
Cell death & disease 2017 Jul 20;8(7):e2946
KMT2A promotes melanoma cell growth by targeting hTERT signaling pathway.
Zhang C, Song C, Liu T, Tang R, Chen M, Gao F, Xiao B, Qin G, Shi F, Li W, Li Y, Fu X, Shi D, Xiao X, Kang L, Huang W, Wu X, Tang B, Deng W
Cell death & disease 2017 Jul 20;8(7):e2940
Cell death & disease 2017 Jul 20;8(7):e2940
A hydrophobic residue in the TALE homeodomain of PBX1 promotes epithelial-to-mesenchymal transition of gastric carcinoma.
He C, Wang Z, Zhang L, Yang L, Li J, Chen X, Zhang J, Chang Q, Yu Y, Liu B, Zhu Z
Oncotarget 2017 Jul 18;8(29):46818-46833
Oncotarget 2017 Jul 18;8(29):46818-46833
Novel function of pregnancy-associated plasma protein A: promotes endometrium receptivity by up-regulating N-fucosylation.
Yu M, Wang J, Liu S, Wang X, Yan Q
Scientific reports 2017 Jul 13;7(1):5315
Scientific reports 2017 Jul 13;7(1):5315
Hydrogen sulfide attenuates cardiac injury in takotsubo cardiomyopathy by alleviating oxidative stress.
Zhang Z, Jin S, Teng X, Duan X, Chen Y, Wu Y
Nitric oxide : biology and chemistry 2017 Jul 1;67:10-25
Nitric oxide : biology and chemistry 2017 Jul 1;67:10-25
Feeding influences adipose tissue responses to exercise in overweight men.
Chen YC, Travers RL, Walhin JP, Gonzalez JT, Koumanov F, Betts JA, Thompson D
American journal of physiology. Endocrinology and metabolism 2017 Jul 1;313(1):E84-E93
American journal of physiology. Endocrinology and metabolism 2017 Jul 1;313(1):E84-E93
Resveratrol Pretreatment Decreases Ischemic Injury and Improves Neurological Function Via Sonic Hedgehog Signaling After Stroke in Rats.
Yu P, Wang L, Tang F, Zeng L, Zhou L, Song X, Jia W, Chen J, Yang Q
Molecular neurobiology 2017 Jan;54(1):212-226
Molecular neurobiology 2017 Jan;54(1):212-226
H/ACA Box Small Nucleolar RNA 7A Promotes the Self-Renewal of Human Umbilical Cord Mesenchymal Stem Cells.
Zhang Y, Xu C, Gu D, Wu M, Yan B, Xu Z, Wang Y, Liu H
Stem cells (Dayton, Ohio) 2017 Jan;35(1):222-235
Stem cells (Dayton, Ohio) 2017 Jan;35(1):222-235
Runx2, a novel regulator for goblet cell differentiation and asthma development.
Shi N, Zhang J, Chen SY
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2017 Jan;31(1):412-420
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2017 Jan;31(1):412-420
Cigarette smoke extract-induced proliferation of normal human urothelial cells via the MAPK/AP-1 pathway.
Geng H, Zhao L, Liang Z, Zhang Z, Xie D, Bi L, Wang Y, Zhang T, Cheng L, Yu D, Zhong C
Oncology letters 2017 Jan;13(1):469-475
Oncology letters 2017 Jan;13(1):469-475
Anti-inflammatory and neuroprotective effects of sanguinarine following cerebral ischemia in rats.
Wang Q, Dai P, Bao H, Liang P, Wang W, Xing A, Sun J
Experimental and therapeutic medicine 2017 Jan;13(1):263-268
Experimental and therapeutic medicine 2017 Jan;13(1):263-268
Forkhead box P3 regulates ARHGAP15 expression and affects migration of glioma cells through the Rac1 signaling pathway.
Sun Z, Zhang B, Wang C, Fu T, Li L, Wu Q, Cai Y, Wang J
Cancer science 2017 Jan;108(1):61-72
Cancer science 2017 Jan;108(1):61-72
Long-term exposure to a 'safe' dose of bisphenol A reduced protein acetylation in adult rat testes.
Chen Z, Zuo X, He D, Ding S, Xu F, Yang H, Jin X, Fan Y, Ying L, Tian C, Ying C
Scientific reports 2017 Jan 9;7:40337
Scientific reports 2017 Jan 9;7:40337
Identification of a novel missense mutation of MIP in a Chinese family with congenital cataracts by target region capture sequencing.
Jiang B, Chen Y, Xu B, Hong N, Liu R, Qi M, Shen L
Scientific reports 2017 Jan 6;7:40129
Scientific reports 2017 Jan 6;7:40129
The RhoA/ROCK Pathway Ameliorates Adhesion and Inflammatory Infiltration Induced by AGEs in Glomerular Endothelial Cells.
Rao J, Ye Z, Tang H, Wang C, Peng H, Lai W, Li Y, Huang W, Lou T
Scientific reports 2017 Jan 5;7:39727
Scientific reports 2017 Jan 5;7:39727
Endothelial microparticles are increased in congenital heart diseases and contribute to endothelial dysfunction.
Lin ZB, Ci HB, Li Y, Cheng TP, Liu DH, Wang YS, Xu J, Yuan HX, Li HM, Chen J, Zhou L, Wang ZP, Zhang X, Ou ZJ, Ou JS
Journal of translational medicine 2017 Jan 4;15(1):4
Journal of translational medicine 2017 Jan 4;15(1):4
Genetic and epigenetic silencing of mircoRNA-506-3p enhances COTL1 oncogene expression to foster non-small lung cancer progression.
Guo S, Yang P, Jiang X, Li X, Wang Y, Zhang X, Sun B, Zhang Y, Jia Y
Oncotarget 2017 Jan 3;8(1):644-657
Oncotarget 2017 Jan 3;8(1):644-657
Metformin Induces Growth Inhibition and Cell Cycle Arrest by Upregulating MicroRNA34a in Renal Cancer Cells.
Xie W, Wang L, Sheng H, Qiu J, Zhang D, Zhang L, Yang F, Tang D, Zhang K
Medical science monitor : international medical journal of experimental and clinical research 2017 Jan 3;23:29-37
Medical science monitor : international medical journal of experimental and clinical research 2017 Jan 3;23:29-37
DAZ-interacting Protein 1 (Dzip1) Phosphorylation by Polo-like Kinase 1 (Plk1) Regulates the Centriolar Satellite Localization of the BBSome Protein during the Cell Cycle.
Zhang B, Wang G, Xu X, Yang S, Zhuang T, Wang G, Ren H, Cheng SY, Jiang Q, Zhang C
The Journal of biological chemistry 2017 Jan 27;292(4):1351-1360
The Journal of biological chemistry 2017 Jan 27;292(4):1351-1360
Resveratrol reverses Doxorubicin resistance by inhibiting epithelial-mesenchymal transition (EMT) through modulating PTEN/Akt signaling pathway in gastric cancer.
Xu J, Liu D, Niu H, Zhu G, Xu Y, Ye D, Li J, Zhang Q
Journal of experimental & clinical cancer research : CR 2017 Jan 26;36(1):19
Journal of experimental & clinical cancer research : CR 2017 Jan 26;36(1):19
Hormetic effect of panaxatriol saponins confers neuroprotection in PC12 cells and zebrafish through PI3K/AKT/mTOR and AMPK/SIRT1/FOXO3 pathways.
Zhang C, Li C, Chen S, Li Z, Ma L, Jia X, Wang K, Bao J, Liang Y, Chen M, Li P, Su H, Lee SM, Liu K, Wan JB, He C
Scientific reports 2017 Jan 23;7:41082
Scientific reports 2017 Jan 23;7:41082
Up-regulation of syncytin-1 contributes to TNF-α-enhanced fusion between OSCC and HUVECs partly via Wnt/β-catenin-dependent pathway.
Yan TL, Wang M, Xu Z, Huang CM, Zhou XC, Jiang EH, Zhao XP, Song Y, Song K, Shao Z, Liu K, Shang ZJ
Scientific reports 2017 Jan 23;7:40983
Scientific reports 2017 Jan 23;7:40983
B7-H3 regulates lipid metabolism of lung cancer through SREBP1-mediated expression of FASN.
Luo D, Xiao H, Dong J, Li Y, Feng G, Cui M, Fan S
Biochemical and biophysical research communications 2017 Jan 22;482(4):1246-1251
Biochemical and biophysical research communications 2017 Jan 22;482(4):1246-1251
Highly expressed lncRNA CCND2-AS1 promotes glioma cell proliferation through Wnt/β-catenin signaling.
Zhang H, Wei DL, Wan L, Yan SF, Sun YH
Biochemical and biophysical research communications 2017 Jan 22;482(4):1219-1225
Biochemical and biophysical research communications 2017 Jan 22;482(4):1219-1225
Secreted miR-27a Induced by Cyclic Stretch Modulates the Proliferation of Endothelial Cells in Hypertension via GRK6.
Wang L, Bao H, Wang KX, Zhang P, Yao QP, Chen XH, Huang K, Qi YX, Jiang ZL
Scientific reports 2017 Jan 20;7:41058
Scientific reports 2017 Jan 20;7:41058
Identification of TDP-43 as an oncogene in melanoma and its function during melanoma pathogenesis.
Zeng Q, Cao K, Liu R, Huang J, Xia K, Tang J, Chen X, Zhou M, Xie H, Zhou J
Cancer biology & therapy 2017 Jan 2;18(1):8-15
Cancer biology & therapy 2017 Jan 2;18(1):8-15
A comprehensive platform for the analysis of ubiquitin-like protein modifications using in vivo biotinylation.
Pirone L, Xolalpa W, Sigurðsson JO, Ramirez J, Pérez C, González M, de Sabando AR, Elortza F, Rodriguez MS, Mayor U, Olsen JV, Barrio R, Sutherland JD
Scientific reports 2017 Jan 18;7:40756
Scientific reports 2017 Jan 18;7:40756
Melatonin ameliorates amygdala-dependent emotional memory deficits in Tg2576 mice by up-regulating the CREB/c-Fos pathway.
Peng C, Hong X, Chen W, Zhang H, Tan L, Wang X, Ding Y, He J
Neuroscience letters 2017 Jan 18;638:76-82
Neuroscience letters 2017 Jan 18;638:76-82
Retromer- and WASH-dependent sorting of nutrient transporters requires a multivalent interaction network with ANKRD50.
Kvainickas A, Orgaz AJ, Nägele H, Diedrich B, Heesom KJ, Dengjel J, Cullen PJ, Steinberg F
Journal of cell science 2017 Jan 15;130(2):382-395
Journal of cell science 2017 Jan 15;130(2):382-395
Contractile forces at tricellular contacts modulate epithelial organization and monolayer integrity.
Salomon J, Gaston C, Magescas J, Duvauchelle B, Canioni D, Sengmanivong L, Mayeux A, Michaux G, Campeotto F, Lemale J, Viala J, Poirier F, Minc N, Schmitz J, Brousse N, Ladoux B, Goulet O, Delacour D
Nature communications 2017 Jan 13;8:13998
Nature communications 2017 Jan 13;8:13998
CRB3 regulates contact inhibition by activating the Hippo pathway in mammary epithelial cells.
Mao X, Li P, Wang Y, Liang Z, Liu J, Li J, Jiang Y, Bao G, Li L, Zhu B, Ren Y, Zhao X, Zhang J, Liu Y, Yang J, Liu P
Cell death & disease 2017 Jan 12;8(1):e2546
Cell death & disease 2017 Jan 12;8(1):e2546
TRIM52: A nuclear TRIM protein that positively regulates the nuclear factor-kappa B signaling pathway.
Fan W, Liu T, Li X, Zhou Y, Wu M, Cui X, Chen H, Qian P
Molecular immunology 2017 Feb;82:114-122
Molecular immunology 2017 Feb;82:114-122
MicroRNA-22 regulates inflammation and angiogenesis via targeting VE-cadherin.
Gu W, Zhan H, Zhou XY, Yao L, Yan M, Chen A, Liu J, Ren X, Zhang X, Liu JX, Liu G
FEBS letters 2017 Feb;591(3):513-526
FEBS letters 2017 Feb;591(3):513-526
Upregulation of miR-146a by YY1 depletion correlates with delayed progression of prostate cancer.
Huang Y, Tao T, Liu C, Guan H, Zhang G, Ling Z, Zhang L, Lu K, Chen S, Xu B, Chen M
International journal of oncology 2017 Feb;50(2):421-431
International journal of oncology 2017 Feb;50(2):421-431
MicroRNA-503-5p inhibits stretch-induced osteogenic differentiation and bone formation.
Liu L, Liu M, Li R, Liu H, Du L, Chen H, Zhang Y, Zhang S, Liu D
Cell biology international 2017 Feb;41(2):112-123
Cell biology international 2017 Feb;41(2):112-123
Expression of glia maturation factor γ is associated with colorectal cancer metastasis and its downregulation suppresses colorectal cancer cell migration and invasion in vitro.
Wang H, Chen Z, Chang H, Mu X, Deng W, Yuan Z, Yao F, Liu Y, Mai R, Wu B
Oncology reports 2017 Feb;37(2):929-936
Oncology reports 2017 Feb;37(2):929-936
Long Noncoding RNA DANCR Is a Positive Regulator of Proliferation and Chondrogenic Differentiation in Human Synovium-Derived Stem Cells.
Zhang L, Yang C, Chen S, Wang G, Shi B, Tao X, Zhou L, Zhao J
DNA and cell biology 2017 Feb;36(2):136-142
DNA and cell biology 2017 Feb;36(2):136-142
Diethylstilbestrol activates CatSper and disturbs progesterone actions in human spermatozoa.
Zou QX, Peng Z, Zhao Q, Chen HY, Cheng YM, Liu Q, He YQ, Weng SQ, Wang HF, Wang T, Zheng LP, Luo T
Human reproduction (Oxford, England) 2017 Feb;32(2):290-298
Human reproduction (Oxford, England) 2017 Feb;32(2):290-298
Kukoamine A Prevents Radiation-Induced Neuroinflammation and Preserves Hippocampal Neurogenesis in Rats by Inhibiting Activation of NF-κB and AP-1.
Zhang Y, Gao L, Cheng Z, Cai J, Niu Y, Meng W, Zhao Q
Neurotoxicity research 2017 Feb;31(2):259-268
Neurotoxicity research 2017 Feb;31(2):259-268
Phosphoglycerate mutase 1 regulates dNTP pool and promotes homologous recombination repair in cancer cells.
Qu J, Sun W, Zhong J, Lv H, Zhu M, Xu J, Jin N, Xie Z, Tan M, Lin SH, Geng M, Ding J, Huang M
The Journal of cell biology 2017 Feb;216(2):409-424
The Journal of cell biology 2017 Feb;216(2):409-424
The effect of nuclear factor erythroid 2-related factor/antioxidant response element signalling pathway in the lanthanum chloride-induced impairment of learning and memory in rats.
Zhang L, Yang J, Jin C, Wu S, Lu X, Hu X, Sun Y, Cai Y
Journal of neurochemistry 2017 Feb;140(3):463-475
Journal of neurochemistry 2017 Feb;140(3):463-475
GAPDH-mediated posttranscriptional regulations of sodium channel Scn1a and Scn3a genes under seizure and ketogenic diet conditions.
Lin GW, Lu P, Zeng T, Tang HL, Chen YH, Liu SJ, Gao MM, Zhao QH, Yi YH, Long YS
Neuropharmacology 2017 Feb;113(Pt A):480-489
Neuropharmacology 2017 Feb;113(Pt A):480-489
Triggering of apoptosis in osteosarcoma cells by graphene/single-walled carbon nanotube hybrids via the ROS-mediated mitochondrial pathway.
Yan X, Yang W, Shao Z, Yang S, Liu X
Journal of biomedical materials research. Part A 2017 Feb;105(2):443-453
Journal of biomedical materials research. Part A 2017 Feb;105(2):443-453
Quercetin induces autophagy via FOXO1-dependent pathways and autophagy suppression enhances quercetin-induced apoptosis in PASMCs in hypoxia.
He Y, Cao X, Guo P, Li X, Shang H, Liu J, Xie M, Xu Y, Liu X
Free radical biology & medicine 2017 Feb;103:165-176
Free radical biology & medicine 2017 Feb;103:165-176
Up-Regulation of RFC3 Promotes Triple Negative Breast Cancer Metastasis and is Associated With Poor Prognosis Via EMT.
He ZY, Wu SG, Peng F, Zhang Q, Luo Y, Chen M, Bao Y
Translational oncology 2017 Feb;10(1):1-9
Translational oncology 2017 Feb;10(1):1-9
LncRNA AK023948 is a positive regulator of AKT.
Koirala P, Huang J, Ho TT, Wu F, Ding X, Mo YY
Nature communications 2017 Feb 8;8:14422
Nature communications 2017 Feb 8;8:14422
Decreased expression of STING predicts poor prognosis in patients with gastric cancer.
Song S, Peng P, Tang Z, Zhao J, Wu W, Li H, Shao M, Li L, Yang C, Duan F, Zhang M, Zhang J, Wu H, Li C, Wang X, Wang H, Ruan Y, Gu J
Scientific reports 2017 Feb 8;7:39858
Scientific reports 2017 Feb 8;7:39858
A novel peptide, 9R-P201, strongly inhibits the viability, proliferation and migration of liver cancer HepG2 cells and induces apoptosis by down-regulation of FoxM1 expression.
Bi Z, Liu W, Ding R, Wu Y, Dou R, Zhang W, Yuan X, Liu X, Xiong L, Guo Z, Mao C
European journal of pharmacology 2017 Feb 5;796:175-189
European journal of pharmacology 2017 Feb 5;796:175-189
Luteolin suppresses gastric cancer progression by reversing epithelial-mesenchymal transition via suppression of the Notch signaling pathway.
Zang MD, Hu L, Fan ZY, Wang HX, Zhu ZL, Cao S, Wu XY, Li JF, Su LP, Li C, Zhu ZG, Yan M, Liu BY
Journal of translational medicine 2017 Feb 27;15(1):52
Journal of translational medicine 2017 Feb 27;15(1):52
HnRNP-L mediates bladder cancer progression by inhibiting apoptotic signaling and enhancing MAPK signaling pathways.
Lv D, Wu H, Xing R, Shu F, Lei B, Lei C, Zhou X, Wan B, Yang Y, Zhong L, Mao X, Zou Y
Oncotarget 2017 Feb 21;8(8):13586-13599
Oncotarget 2017 Feb 21;8(8):13586-13599
Simvastatin suppresses the DNA replication licensing factor MCM7 and inhibits the growth of tamoxifen-resistant breast cancer cells.
Liang Z, Li W, Liu J, Li J, He F, Jiang Y, Yang L, Li P, Wang B, Wang Y, Ren Y, Yang J, Luo Z, Vaziri C, Liu P
Scientific reports 2017 Feb 2;7:41776
Scientific reports 2017 Feb 2;7:41776
Method for Dual Viral Vector Mediated CRISPR-Cas9 Gene Disruption in Primary Human Endothelial Cells.
Gong H, Liu M, Klomp J, Merrill BJ, Rehman J, Malik AB
Scientific reports 2017 Feb 15;7:42127
Scientific reports 2017 Feb 15;7:42127
RELM-β promotes human pulmonary artery smooth muscle cell proliferation via FAK-stimulated surviving.
Lin C, Li X, Luo Q, Yang H, Li L, Zhou Q, Li Y, Tang H, Wu L
Experimental cell research 2017 Feb 1;351(1):43-50
Experimental cell research 2017 Feb 1;351(1):43-50
Sinomenine hydrochloride attenuates the proliferation, migration, invasiveness, angiogenesis and epithelial-mesenchymal transition of clear-cell renal cell carcinoma cells via targeting Smad in vitro.
Zhao B, Liu L, Mao J, Liu K, Fan W, Liu J, Zhang Z, Li Q
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2017 Dec;96:1036-1044
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2017 Dec;96:1036-1044
Long non-coding RNA CASC15 is upregulated in hepatocellular carcinoma and facilitates hepatocarcinogenesis.
He T, Zhang L, Kong Y, Huang Y, Zhang Y, Zhou D, Zhou X, Yan Y, Zhang L, Lu S, Zhou J, Wang W
International journal of oncology 2017 Dec;51(6):1722-1730
International journal of oncology 2017 Dec;51(6):1722-1730
MTA-induced Notch activation enhances the proliferation of human dental pulp cells by inhibiting autophagic flux.
Qiu W, Sun B, He F, Zhang Y
International endodontic journal 2017 Dec;50 Suppl 2:e52-e62
International endodontic journal 2017 Dec;50 Suppl 2:e52-e62
Productive HBV infection of well-differentiated, hNTCP-expressing human hepatoma-derived (Huh7) cells.
Zhou M, Zhao K, Yao Y, Yuan Y, Pei R, Wang Y, Chen J, Hu X, Zhou Y, Chen X, Wu C
Virologica Sinica 2017 Dec;32(6):465-475
Virologica Sinica 2017 Dec;32(6):465-475
Glucose potentiates β-cell function by inducing Tph1 expression in rat islets.
Zhang Y, Deng R, Yang X, Xu W, Liu Y, Li F, Zhang J, Tang H, Ji X, Bi Y, Wang X, Zhou L, Ning G
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2017 Dec;31(12):5342-5355
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2017 Dec;31(12):5342-5355
MicroRNA-200c impairs uterine receptivity formation by targeting FUT4 and α1,3-fucosylation.
Zheng Q, Zhang D, Yang YU, Cui X, Sun J, Liang C, Qin H, Yang X, Liu S, Yan Q
Cell death and differentiation 2017 Dec;24(12):2161-2172
Cell death and differentiation 2017 Dec;24(12):2161-2172
MiR-616 promotes proliferation and inhibits apoptosis in glioma cells by suppressing expression of SOX7 via the Wnt signaling pathway.
Bai QL, Hu CW, Wang XR, Shang JX, Yin GF
European review for medical and pharmacological sciences 2017 Dec;21(24):5630-5637
European review for medical and pharmacological sciences 2017 Dec;21(24):5630-5637
Expression of PTEN-long mediated by CRISPR/Cas9 can repress U87 cell proliferation.
Fang N, Gu T, Wang Y, Wang S, Wang F, An Y, Wei W, Zhang W, Guo X, Nazarali AJ, Ji S
Journal of cellular and molecular medicine 2017 Dec;21(12):3337-3346
Journal of cellular and molecular medicine 2017 Dec;21(12):3337-3346
POSH participates in epileptogenesis by increasing the surface expression of the NMDA receptor: a promising therapeutic target for epilepsy.
Wang X, Tian X, Yang Y, Lu X, Li Y, Ma Y, Zhang Y, Zheng F, Lu S, Xu D, Xu X, Wang W, Wang X
Expert opinion on therapeutic targets 2017 Dec;21(12):1083-1094
Expert opinion on therapeutic targets 2017 Dec;21(12):1083-1094
The reproductive toxicology of male SD rats after PM2.5 exposure mediated by the stimulation of endoplasmic reticulum stress.
Liu X, Jin X, Su R, Li Z
Chemosphere 2017 Dec;189:547-555
Chemosphere 2017 Dec;189:547-555
Autophagy is essential for flavopiridol‑induced cytotoxicity against MCF‑7 breast cancer cells.
Wang S, Wang K, Wang H, Han J, Sun H
Molecular medicine reports 2017 Dec;16(6):9715-9720
Molecular medicine reports 2017 Dec;16(6):9715-9720
Propofol regulates the expression of TLR4 through miR‑21 in human umbilical vein endothelial cells.
Ma L, Yang Y, Sun X, Jiang M, Ma Y, Yang X, Guo Z
Molecular medicine reports 2017 Dec;16(6):9074-9080
Molecular medicine reports 2017 Dec;16(6):9074-9080
EPAC-RAP1 Axis-Mediated Switch in the Response of Primary and Metastatic Melanoma to Cyclic AMP.
Rodríguez CI, Castro-Pérez E, Prabhakar K, Block L, Longley BJ, Wisinski JA, Kimple ME, Setaluri V
Molecular cancer research : MCR 2017 Dec;15(12):1792-1802
Molecular cancer research : MCR 2017 Dec;15(12):1792-1802
Molecular mechanisms in vascular injury induced by hypertension: Expression and role of microRNA-34a.
Liu S, Yi F, Cheng W, Qu X, Wang C
Experimental and therapeutic medicine 2017 Dec;14(6):5497-5502
Experimental and therapeutic medicine 2017 Dec;14(6):5497-5502
Alginate enhances Toll-like receptor 4-mediated phagocytosis by murine RAW264.7 macrophages.
Bi D, Zhou R, Cai N, Lai Q, Han Q, Peng Y, Jiang Z, Tang Z, Lu J, Bao W, Xu H, Xu X
International journal of biological macromolecules 2017 Dec;105(Pt 2):1446-1454
International journal of biological macromolecules 2017 Dec;105(Pt 2):1446-1454
Biologico-clinical significance of DNMT3A variants expression in acute myeloid leukemia.
Lin N, Fu W, Zhao C, Li B, Yan X, Li Y
Biochemical and biophysical research communications 2017 Dec 9;494(1-2):270-277
Biochemical and biophysical research communications 2017 Dec 9;494(1-2):270-277
Upregulation of miR-126-3p promotes human saphenous vein endothelial cell proliferation in vitro and prevents vein graft neointimal formation ex vivo and in vivo.
Qu Q, Bing W, Meng X, Xi J, Bai X, Liu Q, Guo Y, Zhao X, Bi Y
Oncotarget 2017 Dec 5;8(63):106790-106806
Oncotarget 2017 Dec 5;8(63):106790-106806
A novel KCND3 mutation associated with early-onset lone atrial fibrillation.
Huang Y, Yang J, Xie W, Li Q, Zeng Z, Sui H, Shan Z, Huang Z
Oncotarget 2017 Dec 29;8(70):115503-115512
Oncotarget 2017 Dec 29;8(70):115503-115512
EGFR expression in patients with stage III colorectal cancer after adjuvant chemotherapy and on cancer cell function.
Huang CW, Chen YT, Tsai HL, Yeh YS, Su WC, Ma CJ, Tsai TN, Wang JY
Oncotarget 2017 Dec 29;8(70):114663-114676
Oncotarget 2017 Dec 29;8(70):114663-114676
Respiratory Syncytial Virus Nonstructural Protein 1 Blocks Glucocorticoid Receptor Nuclear Translocation by Targeting IPO13 and May Account for Glucocorticoid Insensitivity.
Xie J, Long X, Gao L, Chen S, Zhao K, Li W, Zhou N, Zang N, Deng Y, Ren L, Wang L, Luo Z, Tu W, Zhao X, Fu Z, Xie X, Liu E
The Journal of infectious diseases 2017 Dec 27;217(1):35-46
The Journal of infectious diseases 2017 Dec 27;217(1):35-46
Interactions between GHRH and GABAARs in the brains of patients with epilepsy and in animal models of epilepsy.
Tang S, Luo Z, Qiu X, Zhang Y, Lu X, Huang H, Xu Z, Xu Z
Scientific reports 2017 Dec 22;7(1):18110
Scientific reports 2017 Dec 22;7(1):18110
Morin enhances hepatic Nrf2 expression in a liver fibrosis rat model.
Sang L, Wang XM, Xu DY, Sang LX, Han Y, Jiang LY
World journal of gastroenterology 2017 Dec 21;23(47):8334-8344
World journal of gastroenterology 2017 Dec 21;23(47):8334-8344
ICAM-1 regulates macrophage polarization by suppressing MCP-1 expression via miR-124 upregulation.
Gu W, Yao L, Li L, Zhang J, Place AT, Minshall RD, Liu G
Oncotarget 2017 Dec 19;8(67):111882-111901
Oncotarget 2017 Dec 19;8(67):111882-111901
Disruption of the c-Myc/miR-200b-3p/PRDX2 regulatory loop enhances tumor metastasis and chemotherapeutic resistance in colorectal cancer.
Lv Z, Wei J, You W, Wang R, Shang J, Xiong Y, Yang H, Yang X, Fu Z
Journal of translational medicine 2017 Dec 19;15(1):257
Journal of translational medicine 2017 Dec 19;15(1):257
Bifunctional enzyme ATIC promotes propagation of hepatocellular carcinoma by regulating AMPK-mTOR-S6 K1 signaling.
Li M, Jin C, Xu M, Zhou L, Li D, Yin Y
Cell communication and signaling : CCS 2017 Dec 16;15(1):52
Cell communication and signaling : CCS 2017 Dec 16;15(1):52
Mammalian Numb protein antagonizes Notch by controlling postendocytic trafficking of the Notch ligand Delta-like 4.
Shao X, Ding Z, Zhao M, Liu K, Sun H, Chen J, Liu X, Zhang Y, Hong Y, Li H, Li H
The Journal of biological chemistry 2017 Dec 15;292(50):20628-20643
The Journal of biological chemistry 2017 Dec 15;292(50):20628-20643
Interleukin-22 participates in the inflammatory process of vitiligo.
Dong J, An X, Zhong H, Wang Y, Shang J, Zhou J
Oncotarget 2017 Dec 12;8(65):109161-109174
Oncotarget 2017 Dec 12;8(65):109161-109174
HRD1 prevents apoptosis in renal tubular epithelial cells by mediating eIF2α ubiquitylation and degradation.
Huang Y, Sun Y, Cao Y, Sun H, Li M, You H, Su D, Li Y, Liang X
Cell death & disease 2017 Dec 11;8(12):3202
Cell death & disease 2017 Dec 11;8(12):3202
Human Cytomegalovirus Encoded miR-US25-1-5p Attenuates CD147/EMMPRIN-Mediated Early Antiviral Response.
Chen J, Xia S, Yang X, Chen H, Li F, Liu F, Chen Z
Viruses 2017 Dec 1;9(12)
Viruses 2017 Dec 1;9(12)
Bisphenol a induces autophagy and apoptosis concurrently involving the Akt/mTOR pathway in testes of pubertal SD rats.
Quan C, Wang C, Duan P, Huang W, Chen W, Tang S, Yang K
Environmental toxicology 2017 Aug;32(8):1977-1989
Environmental toxicology 2017 Aug;32(8):1977-1989
Looping-out mechanism for resolution of replicative stress at telomeres.
Zhang T, Zhang Z, Li F, Hu Q, Liu H, Tang M, Ma W, Huang J, Songyang Z, Rong Y, Zhang S, Chen BP, Zhao Y
EMBO reports 2017 Aug;18(8):1412-1428
EMBO reports 2017 Aug;18(8):1412-1428
MicroRNA-149 contributes to scarless wound healing by attenuating inflammatory response.
Lang H, Zhao F, Zhang T, Liu X, Wang Z, Wang R, Shi P, Pang X
Molecular medicine reports 2017 Aug;16(2):2156-2162
Molecular medicine reports 2017 Aug;16(2):2156-2162
Protective effect of lutein on ARPE-19 cells upon H2O2-induced G2/M arrest.
Liu H, Liu W, Zhou X, Long C, Kuang X, Hu J, Tang Y, Liu L, He J, Huang Z, Fan Y, Jin G, Zhang Q, Shen H
Molecular medicine reports 2017 Aug;16(2):2069-2074
Molecular medicine reports 2017 Aug;16(2):2069-2074
Intermedin improves cardiac function and sympathetic neural remodeling in a rat model of post myocardial infarction heart failure.
Xu B, Xu H, Cao H, Liu X, Qin C, Zhao Y, Han X, Li H
Molecular medicine reports 2017 Aug;16(2):1723-1730
Molecular medicine reports 2017 Aug;16(2):1723-1730
The effects of hyperoside on apoptosis and the expression of Fas/FasL and survivin in SW579 human thyroid squamous cell carcinoma cell line.
Liu Z, Liu G, Liu X, Li S
Oncology letters 2017 Aug;14(2):2310-2314
Oncology letters 2017 Aug;14(2):2310-2314
Treatment mechanism of matrine in combination with irinotecan for colon cancer.
Duan L, Deng L, Wang D, Ma S, Li C, Zhao D
Oncology letters 2017 Aug;14(2):2300-2304
Oncology letters 2017 Aug;14(2):2300-2304
HRS plays an important role for TLR7 signaling to orchestrate inflammation and innate immunity upon EV71 infection.
Luo Z, Ge M, Chen J, Geng Q, Tian M, Qiao Z, Bai L, Zhang Q, Zhu C, Xiong Y, Wu K, Liu F, Liu Y, Wu J
PLoS pathogens 2017 Aug;13(8):e1006585
PLoS pathogens 2017 Aug;13(8):e1006585
Calpain Inhibition Is Protective in Machado-Joseph Disease Zebrafish Due to Induction of Autophagy.
Watchon M, Yuan KC, Mackovski N, Svahn AJ, Cole NJ, Goldsbury C, Rinkwitz S, Becker TS, Nicholson GA, Laird AS
The Journal of neuroscience : the official journal of the Society for Neuroscience 2017 Aug 9;37(32):7782-7794
The Journal of neuroscience : the official journal of the Society for Neuroscience 2017 Aug 9;37(32):7782-7794
The impact of p53 on the early stage replication of retrovirus.
Kinnetz M, Alghamdi F, Racz M, Hu W, Shi B
Virology journal 2017 Aug 9;14(1):151
Virology journal 2017 Aug 9;14(1):151
Platelet Derived Growth Factor Alpha (PDGFRα) Induces the Activation of Cardiac Fibroblasts by Activating c-Kit.
Wang L, Yue Y, Yang X, Fan T, Mei B, Hou J, Liang M, Chen G, Wu Z
Medical science monitor : international medical journal of experimental and clinical research 2017 Aug 6;23:3808-3816
Medical science monitor : international medical journal of experimental and clinical research 2017 Aug 6;23:3808-3816
TIMELESS confers cisplatin resistance in nasopharyngeal carcinoma by activating the Wnt/β-catenin signaling pathway and promoting the epithelial mesenchymal transition.
Liu SL, Lin HX, Lin CY, Sun XQ, Ye LP, Qiu F, Wen W, Hua X, Wu XQ, Li J, Song LB, Guo L
Cancer letters 2017 Aug 28;402:117-130
Cancer letters 2017 Aug 28;402:117-130
CO-releasing molecules-2 attenuates ox-LDL-induced injury in HUVECs by ameliorating mitochondrial function and inhibiting Wnt/β-catenin pathway.
Sun HJ, Xu DY, Sun YX, Xue T, Zhang CX, Zhang ZX, Lin W, Li KX
Biochemical and biophysical research communications 2017 Aug 26;490(3):629-635
Biochemical and biophysical research communications 2017 Aug 26;490(3):629-635
A Chinese herbal formula, Jian-Pi-Yi-Shen decoction, improves muscle atrophy via regulating mitochondrial quality control process in 5/6 nephrectomised rats.
Wang D, Chen J, Liu X, Zheng P, Song G, Yi T, Li S
Scientific reports 2017 Aug 23;7(1):9253
Scientific reports 2017 Aug 23;7(1):9253
Mediator MED23 Links Pigmentation and DNA Repair through the Transcription Factor MITF.
Xia M, Chen K, Yao X, Xu Y, Yao J, Yan J, Shao Z, Wang G
Cell reports 2017 Aug 22;20(8):1794-1804
Cell reports 2017 Aug 22;20(8):1794-1804
Activation of Nrf2/ARE signaling pathway attenuates lanthanum chloride induced injuries in primary rat astrocytes.
Zhang L, Yang J, Wu S, Jin C, Lu X, Hu X, Sun Y, Gao X, Cai Y
Metallomics : integrated biometal science 2017 Aug 16;9(8):1120-1131
Metallomics : integrated biometal science 2017 Aug 16;9(8):1120-1131
Seneca Valley Virus Suppresses Host Type I Interferon Production by Targeting Adaptor Proteins MAVS, TRIF, and TANK for Cleavage.
Qian S, Fan W, Liu T, Wu M, Zhang H, Cui X, Zhou Y, Hu J, Wei S, Chen H, Li X, Qian P
Journal of virology 2017 Aug 15;91(16)
Journal of virology 2017 Aug 15;91(16)
microRNA-451-modulated hnRNP A1 takes a part in granulocytic differentiation regulation and acute myeloid leukemia.
Song L, Lin HS, Gong JN, Han H, Wang XS, Su R, Chen MT, Shen C, Ma YN, Yu J, Zhang JW
Oncotarget 2017 Aug 15;8(33):55453-55466
Oncotarget 2017 Aug 15;8(33):55453-55466
Neuronal zinc-α2-glycoprotein is decreased in temporal lobe epilepsy in patients and rats.
Liu Y, Wang T, Liu X, Wei X, Xu T, Yin M, Ding X, Mo L, Chen L
Neuroscience 2017 Aug 15;357:56-66
Neuroscience 2017 Aug 15;357:56-66
Flavonoid glycosides isolated from Epimedium brevicornum and their estrogen biosynthesis-promoting effects.
Li F, Du BW, Lu DF, Wu WX, Wongkrajang K, Wang L, Pu WC, Liu CL, Liu HW, Wang MK, Wang F
Scientific reports 2017 Aug 10;7(1):7760
Scientific reports 2017 Aug 10;7(1):7760
AMPK Serves as a Therapeutic Target Against Anemia of Inflammation.
Wang M, Xin H, Tang W, Li Y, Zhang Z, Fan L, Miao L, Tan B, Wang X, Zhu YZ
Antioxidants & redox signaling 2017 Aug 10;27(5):251-268
Antioxidants & redox signaling 2017 Aug 10;27(5):251-268
Role of RAS/Wnt/β-catenin axis activation in the pathogenesis of podocyte injury and tubulo-interstitial nephropathy.
Chen L, Chen DQ, Wang M, Liu D, Chen H, Dou F, Vaziri ND, Zhao YY
Chemico-biological interactions 2017 Aug 1;273:56-72
Chemico-biological interactions 2017 Aug 1;273:56-72
Transcription factor GATA3 expression is induced by GLS2 overexpression in a glioblastoma cell line but is GLS2-independent in patient-derived glioblastoma.
Majewska E, Rola R, Barczewska M, Marquez J, Albrecht J, Szeliga M
Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 2017 Apr;68(2):209-214
Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 2017 Apr;68(2):209-214
The role of metastasis-associated in colon cancer 1 (MACC1) in endometrial carcinoma tumorigenesis and progression.
Chen S, Zong ZH, Wu DD, Sun KX, Liu BL, Zhao Y
Molecular carcinogenesis 2017 Apr;56(4):1361-1371
Molecular carcinogenesis 2017 Apr;56(4):1361-1371
Isoquercetin Ameliorates Cerebral Impairment in Focal Ischemia Through Anti-Oxidative, Anti-Inflammatory, and Anti-Apoptotic Effects in Primary Culture of Rat Hippocampal Neurons and Hippocampal CA1 Region of Rats.
Wang CP, Shi YW, Tang M, Zhang XC, Gu Y, Liang XM, Wang ZW, Ding F
Molecular neurobiology 2017 Apr;54(3):2126-2142
Molecular neurobiology 2017 Apr;54(3):2126-2142
The protective effect of dopamine on ventilator-induced lung injury via the inhibition of NLRP3 inflammasome.
Yang X, Sun X, Chen H, Xi G, Hou Y, Wu J, Liu D, Wang H, Hou Y, Yu J
International immunopharmacology 2017 Apr;45:68-73
International immunopharmacology 2017 Apr;45:68-73
Down-regulation of Pin1 in Temporal Lobe Epilepsy Patients and Mouse Model.
Tang L, Zhang Y, Chen G, Xiong Y, Wang X, Zhu B
Neurochemical research 2017 Apr;42(4):1211-1218
Neurochemical research 2017 Apr;42(4):1211-1218
Protective effect of naringin against the LPS-induced apoptosis of PC12 cells: Implications for the treatment of neurodegenerative disorders.
Wang H, Xu YS, Wang ML, Cheng C, Bian R, Yuan H, Wang Y, Guo T, Zhu LL, Zhou H
International journal of molecular medicine 2017 Apr;39(4):819-830
International journal of molecular medicine 2017 Apr;39(4):819-830
miR-92a promotes tumor growth of osteosarcoma by targeting PTEN/AKT signaling pathway.
Xiao J, Yu W, Hu K, Li M, Chen J, Li Z
Oncology reports 2017 Apr;37(4):2513-2521
Oncology reports 2017 Apr;37(4):2513-2521
miR-30a radiosensitizes non-small cell lung cancer by targeting ATF1 that is involved in the phosphorylation of ATM.
Guo Y, Sun W, Gong T, Chai Y, Wang J, Hui B, Li Y, Song L, Gao Y
Oncology reports 2017 Apr;37(4):1980-1988
Oncology reports 2017 Apr;37(4):1980-1988
Low expression of TMEM67 is a critical predictor of poor prognosis in human urothelial carcinoma of the bladder.
Du E, Zhang C, Qin Z, Yang K, Li C, Wang A, Zhang Z, Xu Y
Urologic oncology 2017 Apr;35(4):152.e7-152.e12
Urologic oncology 2017 Apr;35(4):152.e7-152.e12
The Selective Serotonin Reuptake Inhibitor Fluoxetine Directly Inhibits Osteoblast Differentiation and Mineralization During Fracture Healing in Mice.
Bradaschia-Correa V, Josephson AM, Mehta D, Mizrahi M, Neibart SS, Liu C, Kennedy OD, Castillo AB, Egol KA, Leucht P
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2017 Apr;32(4):821-833
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2017 Apr;32(4):821-833
Interleukin 6 induces cell proliferation of clear cell renal cell carcinoma by suppressing hepaCAM via the STAT3-dependent up-regulation of DNMT1 or DNMT3b.
Quan Z, He Y, Luo C, Xia Y, Zhao Y, Liu N, Wu X
Cellular signalling 2017 Apr;32:48-58
Cellular signalling 2017 Apr;32:48-58
Histone deacetylase inhibitor apicidin increases expression of the α-secretase ADAM10 through transcription factor USF1-mediated mechanisms.
Hu XT, Zhu BL, Zhao LG, Wang JW, Liu L, Lai YJ, He L, Deng XJ, Chen GJ
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2017 Apr;31(4):1482-1493
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2017 Apr;31(4):1482-1493
Blocking the recruitment of naive CD4+ T cells reverses immunosuppression in breast cancer.
Su S, Liao J, Liu J, Huang D, He C, Chen F, Yang L, Wu W, Chen J, Lin L, Zeng Y, Ouyang N, Cui X, Yao H, Su F, Huang JD, Lieberman J, Liu Q, Song E
Cell research 2017 Apr;27(4):461-482
Cell research 2017 Apr;27(4):461-482
Non-hemolytic enterotoxin of Bacillus cereus induces apoptosis in Vero cells.
Liu X, Ding S, Shi P, Dietrich R, Märtlbauer E, Zhu K
Cellular microbiology 2017 Apr;19(4)
Cellular microbiology 2017 Apr;19(4)
Activation of ATP-sensitive potassium channel by iptakalim normalizes stress-induced HPA axis disorder and depressive behaviour by alleviating inflammation and oxidative stress in mouse hypothalamus.
Zhao XJ, Zhao Z, Yang DD, Cao LL, Zhang L, Ji J, Gu J, Huang JY, Sun XL
Brain research bulletin 2017 Apr;130:146-155
Brain research bulletin 2017 Apr;130:146-155
GP73 represses host innate immune response to promote virus replication by facilitating MAVS and TRAF6 degradation.
Zhang X, Zhu C, Wang T, Jiang H, Ren Y, Zhang Q, Wu K, Liu F, Liu Y, Wu J
PLoS pathogens 2017 Apr;13(4):e1006321
PLoS pathogens 2017 Apr;13(4):e1006321
Quercetin exerts preventive, ameliorative and prophylactic effects on cadmium chloride - induced oxidative stress in the uterus and ovaries of female Wistar rats.
Nna VU, Usman UZ, Ofutet EO, Owu DU
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2017 Apr;102:143-155
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2017 Apr;102:143-155
Induction of pro-inflammatory genes by serum amyloid A1 in human amnion fibroblasts.
Li W, Wang W, Zuo R, Liu C, Shu Q, Ying H, Sun K
Scientific reports 2017 Apr 6;7(1):693
Scientific reports 2017 Apr 6;7(1):693
Bone marrow-derived mesenchymal stem cells (BMSCs) repair acute necrotized pancreatitis by secreting microRNA-9 to target the NF-κB1/p50 gene in rats.
Qian D, Wei G, Xu C, He Z, Hua J, Li J, Hu Q, Lin S, Gong J, Meng H, Zhou B, Teng H, Song Z
Scientific reports 2017 Apr 3;7(1):581
Scientific reports 2017 Apr 3;7(1):581
HMGCS2 promotes autophagic degradation of the amyloid-β precursor protein through ketone body-mediated mechanisms.
Hu LT, Zhu BL, Lai YJ, Long Y, Zha JS, Hu XT, Zhang JH, Chen GJ
Biochemical and biophysical research communications 2017 Apr 29;486(2):492-498
Biochemical and biophysical research communications 2017 Apr 29;486(2):492-498
Atorvastatin prevents Angiotensin II induced myocardial hypertrophy in vitro via CCAAT/enhancer-binding protein β.
Chen Y, Yu S, Zhang N, Li Y, Chen S, Chang Y, Sun G, Sun Y
Biochemical and biophysical research communications 2017 Apr 29;486(2):423-430
Biochemical and biophysical research communications 2017 Apr 29;486(2):423-430
DNA replication licensing factor Cdc6 and Plk4 kinase antagonistically regulate centrosome duplication via Sas-6.
Xu X, Huang S, Zhang B, Huang F, Chi W, Fu J, Wang G, Li S, Jiang Q, Zhang C
Nature communications 2017 Apr 27;8:15164
Nature communications 2017 Apr 27;8:15164
CtBP2 overexpression promotes tumor cell proliferation and invasion in gastric cancer and is associated with poor prognosis.
Dai F, Xuan Y, Jin JJ, Yu S, Long ZW, Cai H, Liu XW, Zhou Y, Wang YN, Chen Z, Huang H
Oncotarget 2017 Apr 25;8(17):28736-28749
Oncotarget 2017 Apr 25;8(17):28736-28749
Amelioration of amyloid-β-induced deficits by DcR3 in an Alzheimer's disease model.
Liu YL, Chen WT, Lin YY, Lu PH, Hsieh SL, Cheng IH
Molecular neurodegeneration 2017 Apr 24;12(1):30
Molecular neurodegeneration 2017 Apr 24;12(1):30
Exenatide improves liver mitochondrial dysfunction and insulin resistance by reducing oxidative stress in high fat diet-induced obese mice.
Wang Z, Hou L, Huang L, Guo J, Zhou X
Biochemical and biophysical research communications 2017 Apr 22;486(1):116-123
Biochemical and biophysical research communications 2017 Apr 22;486(1):116-123
Tumor necrosis factor receptor 2/AKT and ERK signaling pathways contribute to the switch from fibroblasts to CAFs by progranulin in microenvironment of colorectal cancer.
Wang L, Yang D, Tian J, Gao A, Shen Y, Ren X, Li X, Jiang G, Dong T
Oncotarget 2017 Apr 18;8(16):26323-26333
Oncotarget 2017 Apr 18;8(16):26323-26333
Satb2 Ablation Impairs Hippocampus-Based Long-Term Spatial Memory and Short-Term Working Memory and Immediate Early Genes (IEGs)-Mediated Hippocampal Synaptic Plasticity.
Li Y, You QL, Zhang SR, Huang WY, Zou WJ, Jie W, Li SJ, Liu JH, Lv CY, Cong J, Hu YY, Gao TM, Li JM
Molecular neurobiology 2017 Apr 18;
Molecular neurobiology 2017 Apr 18;
Identification, expression pattern and functional characterization of As-kip2 in diapause embryo restarting process of Artemia sinica.
Zhang M, Yao F, Qin T, Hou L, Zou X
Gene 2017 Apr 15;608:28-40
Gene 2017 Apr 15;608:28-40
In vitro biomimetic platforms featuring a perfusion system and 3D spheroid culture promote the construction of tissue-engineered corneal endothelial layers.
Li S, Han Y, Lei H, Zeng Y, Cui Z, Zeng Q, Zhu D, Lian R, Zhang J, Chen Z, Chen J
Scientific reports 2017 Apr 10;7(1):777
Scientific reports 2017 Apr 10;7(1):777
Knockdown of Sall4 inhibits intrahepatic cholangiocarcinoma cell migration and invasion in ICC-9810 cells.
Zhu L, Huang F, Deng G, Nie W, Huang W, Xu H, Zheng S, Yi Z, Wan T
OncoTargets and therapy 2016;9:5297-305
OncoTargets and therapy 2016;9:5297-305
Downregulating hypoxia-inducible factor-1α expression with perfluorooctyl-bromide nanoparticles reduces early brain injury following experimental subarachnoid hemorrhage in rats.
Xu W, Xu R, Li X, Zhang H, Wang X, Zhu J
American journal of translational research 2016;8(5):2114-26
American journal of translational research 2016;8(5):2114-26
Down-regulation of long non-coding RNA FOXD3 antisense RNA 1 (FOXD3-AS1) inhibits cell proliferation, migration, and invasion in malignant glioma cells.
Chen ZH, Hu HK, Zhang CR, Lu CY, Bao Y, Cai Z, Zou YX, Hu GH, Jiang L
American journal of translational research 2016;8(10):4106-4119
American journal of translational research 2016;8(10):4106-4119
Upregulation of long non-coding RNA LINC00152 by SP1 contributes to gallbladder cancer cell growth and tumor metastasis via PI3K/AKT pathway.
Cai Q, Wang ZQ, Wang SH, Li C, Zhu ZG, Quan ZW, Zhang WJ
American journal of translational research 2016;8(10):4068-4081
American journal of translational research 2016;8(10):4068-4081
Autophagy postpones apoptotic cell death in PRRSV infection through Bad-Beclin1 interaction.
Zhou A, Li S, Khan FA, Zhang S
Virulence 2016;7(2):98-109
Virulence 2016;7(2):98-109
Yin-Chen-Hao Tang Attenuates Severe Acute Pancreatitis in Rat: An Experimental Verification of In silico Network Target Prediction.
Xiang H, Wang G, Qu J, Xia S, Tao X, Qi B, Zhang Q, Shang D
Frontiers in pharmacology 2016;7:378
Frontiers in pharmacology 2016;7:378
Exogenous Hydrogen Sulfide Attenuates High Glucose-Induced Cardiotoxicity by Inhibiting NLRP3 Inflammasome Activation by Suppressing TLR4/NF-κB Pathway in H9c2 Cells.
Huang Z, Zhuang X, Xie C, Hu X, Dong X, Guo Y, Li S, Liao X
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2016;40(6):1578-1590
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2016;40(6):1578-1590
Parthenolide Induces Reactive Oxygen Species-Mediated Autophagic Cell Death in Human Osteosarcoma Cells.
Yang C, Yang QO, Kong QJ, Yuan W, Ou Yang YP
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2016;40(1-2):146-154
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2016;40(1-2):146-154
FBXO6-Mediated Ubiquitination and Degradation of Ero1L Inhibits Endoplasmic Reticulum Stress-Induced Apoptosis.
Chen X, Duan LH, Luo PC, Hu G, Yu X, Liu J, Lu H, Liu B
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2016;39(6):2501-2508
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2016;39(6):2501-2508
Effect of Type I Diabetes on the Proteome of Mouse Oocytes.
Jiang G, Zhang G, An T, He Z, Kang L, Yang X, Gu Y, Zhang D, Wang Y, Gao S
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2016;39(6):2320-2330
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2016;39(6):2320-2330
Similar efficacy from specific and non-specific mineralocorticoid receptor antagonist treatment of muscular dystrophy mice.
Lowe J, Floyd KT, Rastogi N, Schultz EJ, Chadwick JA, Swager SA, Zins JG, Kadakia FK, Smart S, Gomez-Sanchez EP, Gomez-Sanchez CE, Raman SV, Janssen PM, Rafael-Fortney JA
Journal of neuromuscular diseases 2016;3(3):395-404
Journal of neuromuscular diseases 2016;3(3):395-404
N-Stearoyl-L-Tyrosine Inhibits the Senescence of Neural Stem/Progenitor Cells Induced by Aβ 1-42 via the CB2 Receptor.
Li WQ, Wang ZJ, Liu S, Hu Y, Yin M, Lu Y
Stem cells international 2016;2016:7419389
Stem cells international 2016;2016:7419389
Neurotrophic Effect of Adipose Tissue-Derived Stem Cells on Erectile Function Recovery by Pigment Epithelium-Derived Factor Secretion in a Rat Model of Cavernous Nerve Injury.
Chen X, Yang Q, Zheng T, Bian J, Sun X, Shi Y, Liang X, Gao G, Liu G, Deng C
Stem cells international 2016;2016:5161248
Stem cells international 2016;2016:5161248
HIV-1 Tat Regulates Occludin and Aβ Transfer Receptor Expression in Brain Endothelial Cells via Rho/ROCK Signaling Pathway.
Chen Y, Huang W, Jiang W, Wu X, Ye B, Zhou X
Oxidative medicine and cellular longevity 2016;2016:4196572
Oxidative medicine and cellular longevity 2016;2016:4196572
MiR-20a-5p represses multi-drug resistance in osteosarcoma by targeting the KIF26B gene.
Pu Y, Yi Q, Zhao F, Wang H, Cai W, Cai S
Cancer cell international 2016;16:64
Cancer cell international 2016;16:64
Forsythoside A Inhibits BVDV Replication via TRAF2-Dependent CD28-4-1BB Signaling in Bovine PBMCs.
Song QJ, Weng XG, Cai DJ, Zhang W, Wang JF
PloS one 2016;11(9):e0162791
PloS one 2016;11(9):e0162791
Finasteride Enhances the Generation of Human Myeloid-Derived Suppressor Cells by Up-Regulating the COX2/PGE2 Pathway.
Zhang S, Wu K, Liu Y, Lin Y, Zhang X, Zhou J, Zhang H, Pan T, Fu Y
PloS one 2016;11(6):e0156549
PloS one 2016;11(6):e0156549
Hepatitis B Virus Stimulated Fibronectin Facilitates Viral Maintenance and Replication through Two Distinct Mechanisms.
Ren S, Wang J, Chen TL, Li HY, Wan YS, Peng NF, Gui XE, Zhu Y
PloS one 2016;11(3):e0152721
PloS one 2016;11(3):e0152721
Electroacupuncture Promotes Remyelination after Cuprizone Treatment by Enhancing Myelin Debris Clearance.
Zhu K, Sun J, Kang Z, Zou Z, Wu G, Wang J
Frontiers in neuroscience 2016;10:613
Frontiers in neuroscience 2016;10:613
Low-Dose Endothelial-Monocyte-Activating Polypeptide-II Induced Autophagy by Down-Regulating miR-20a in U-87 and U-251 Glioma Cells.
Chen J, Liu L, Liu Y, Liu X, Qu C, Meng F, Ma J, Lin Y, Xue Y
Frontiers in cellular neuroscience 2016;10:128
Frontiers in cellular neuroscience 2016;10:128
Fluoride induced endoplasmic reticulum stress and calcium overload in ameloblasts.
Zhang Y, Zhang K, Ma L, Gu H, Li J, Lei S
Archives of oral biology 2016 Sep;69:95-101
Archives of oral biology 2016 Sep;69:95-101
Effects of ZnO nanoparticles on perfluorooctane sulfonate induced thyroid-disrupting on zebrafish larvae.
Du J, Wang S, You H, Liu Z
Journal of environmental sciences (China) 2016 Sep;47:153-164
Journal of environmental sciences (China) 2016 Sep;47:153-164
Curcumin Attenuated Bupivacaine-Induced Neurotoxicity in SH-SY5Y Cells Via Activation of the Akt Signaling Pathway.
Fan YL, Li HC, Zhao W, Peng HH, Huang F, Jiang WH, Xu SY
Neurochemical research 2016 Sep;41(9):2425-32
Neurochemical research 2016 Sep;41(9):2425-32
Evodiamine exerts anti-tumor effects against hepatocellular carcinoma through inhibiting β-catenin-mediated angiogenesis.
Shi L, Yang F, Luo F, Liu Y, Zhang F, Zou M, Liu Q
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2016 Sep;37(9):12791-12803
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2016 Sep;37(9):12791-12803
Angiopoietin-like protein 2 expression is suppressed by angiotensin II via the angiotensin II type 1 receptor in rat cardiomyocytes.
Wang S, Li Y, Miao W, Zhao H, Zhang F, Liu N, Su G, Cai X
Molecular medicine reports 2016 Sep;14(3):2607-13
Molecular medicine reports 2016 Sep;14(3):2607-13
Simultaneous inhibition of the ubiquitin-proteasome system and autophagy enhances apoptosis induced by ER stress aggravators in human pancreatic cancer cells.
Li X, Zhu F, Jiang J, Sun C, Zhong Q, Shen M, Wang X, Tian R, Shi C, Xu M, Peng F, Guo X, Hu J, Ye D, Wang M, Qin R
Autophagy 2016 Sep;12(9):1521-37
Autophagy 2016 Sep;12(9):1521-37
Alternative splicing of spleen tyrosine kinase differentially regulates colorectal cancer progression.
Ni B, Hu J, Chen D, Li L, Chen D, Wang J, Wang L
Oncology letters 2016 Sep;12(3):1737-1744
Oncology letters 2016 Sep;12(3):1737-1744
Structure-based discovery of two antiviral inhibitors targeting the NS3 helicase of Japanese encephalitis virus.
Fang J, Li H, Kong D, Cao S, Peng G, Zhou R, Chen H, Song Y
Scientific reports 2016 Sep 29;6:34550
Scientific reports 2016 Sep 29;6:34550
Regulation of PCGEM1 by p54/nrb in prostate cancer.
Ho TT, Huang J, Zhou N, Zhang Z, Koirala P, Zhou X, Wu F, Ding X, Mo YY
Scientific reports 2016 Sep 29;6:34529
Scientific reports 2016 Sep 29;6:34529
Epigenomic profiling of primary gastric adenocarcinoma reveals super-enhancer heterogeneity.
Ooi WF, Xing M, Xu C, Yao X, Ramlee MK, Lim MC, Cao F, Lim K, Babu D, Poon LF, Lin Suling J, Qamra A, Irwanto A, Qu Zhengzhong J, Nandi T, Lee-Lim AP, Chan YS, Tay ST, Lee MH, Davies JO, Wong WK, Soo KC, Chan WH, Ong HS, Chow P, Wong CY, Rha SY, Liu J, Hillmer AM, Hughes JR, Rozen S, Teh BT, Fullwood MJ, Li S, Tan P
Nature communications 2016 Sep 28;7:12983
Nature communications 2016 Sep 28;7:12983
Control of cortex development by ULK4, a rare risk gene for mental disorders including schizophrenia.
Lang B, Zhang L, Jiang G, Hu L, Lan W, Zhao L, Hunter I, Pruski M, Song NN, Huang Y, Zhang L, St Clair D, McCaig CD, Ding YQ
Scientific reports 2016 Sep 27;6:31126
Scientific reports 2016 Sep 27;6:31126
Selenomethionine Ameliorates Neuropathology in the Olfactory Bulb of a Triple Transgenic Mouse Model of Alzheimer's Disease.
Zhang ZH, Chen C, Wu QY, Zheng R, Chen Y, Liu Q, Ni JZ, Song GL
International journal of molecular sciences 2016 Sep 27;17(10)
International journal of molecular sciences 2016 Sep 27;17(10)
TDP-43 aggregation mirrors TDP-43 knockdown, affecting the expression levels of a common set of proteins.
Prpar Mihevc S, Baralle M, Buratti E, Rogelj B
Scientific reports 2016 Sep 26;6:33996
Scientific reports 2016 Sep 26;6:33996
TRIM52 inhibits Japanese Encephalitis Virus replication by degrading the viral NS2A.
Fan W, Wu M, Qian S, Zhou Y, Chen H, Li X, Qian P
Scientific reports 2016 Sep 26;6:33698
Scientific reports 2016 Sep 26;6:33698
Polyphenols from hawthorn peels and fleshes differently mitigate dyslipidemia, inflammation and oxidative stress in association with modulation of liver injury in high fructose diet-fed mice.
Han X, Li W, Huang D, Yang X
Chemico-biological interactions 2016 Sep 25;257:132-40
Chemico-biological interactions 2016 Sep 25;257:132-40
Reversal of cisplatin resistance in non-small cell lung cancer stem cells by Taxus chinensis var.
Jiang YQ, Xu XP, Guo QM, Xu XC, Liu QY, An SH, Xu JL, Su F, Tai JB
Genetics and molecular research : GMR 2016 Sep 2;15(3)
Genetics and molecular research : GMR 2016 Sep 2;15(3)
Triplex structures induce DNA double strand breaks via replication fork collapse in NER deficient cells.
Kaushik Tiwari M, Adaku N, Peart N, Rogers FA
Nucleic acids research 2016 Sep 19;44(16):7742-54
Nucleic acids research 2016 Sep 19;44(16):7742-54
miR-106a promotes cardiac hypertrophy by targeting mitofusin 2.
Guan X, Wang L, Liu Z, Guo X, Jiang Y, Lu Y, Peng Y, Liu T, Yang B, Shan H, Zhang Y, Xu C
Journal of molecular and cellular cardiology 2016 Oct;99:207-217
Journal of molecular and cellular cardiology 2016 Oct;99:207-217
SIRT1 activator ameliorates the renal tubular injury induced by hyperglycemia in vivo and in vitro via inhibiting apoptosis.
Wang XL, Wu LY, Zhao L, Sun LN, Liu HY, Liu G, Guan GJ
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2016 Oct;83:41-50
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2016 Oct;83:41-50
Prognostic value of mixed lineage kinase domain-like protein expression in the survival of patients with gastric caner.
Ertao Z, Jianhui C, Kang W, Zhijun Y, Hui W, Chuangqi C, Changjiang Q, Sile C, Yulong H, Shirong C
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2016 Oct;37(10):13679-13685
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2016 Oct;37(10):13679-13685
Neuroprotective Effects of Dexmedetomidine Against Hypoxia-Induced Nervous System Injury are Related to Inhibition of NF-κB/COX-2 Pathways.
Pan W, Lin L, Zhang N, Yuan F, Hua X, Wang Y, Mo L
Cellular and molecular neurobiology 2016 Oct;36(7):1179-88
Cellular and molecular neurobiology 2016 Oct;36(7):1179-88
Inhibition of Lysyl Oxidase by Cortisol Regeneration in Human Amnion: Implications for Rupture of Fetal Membranes.
Liu C, Guo C, Wang W, Zhu P, Li W, Mi Y, Myatt L, Sun K
Endocrinology 2016 Oct;157(10):4055-4065
Endocrinology 2016 Oct;157(10):4055-4065
Nanoparticle-facilitated autophagy inhibition promotes the efficacy of chemotherapeutics against breast cancer stem cells.
Sun R, Shen S, Zhang YJ, Xu CF, Cao ZT, Wen LP, Wang J
Biomaterials 2016 Oct;103:44-55
Biomaterials 2016 Oct;103:44-55
Long non-coding RNA H19 regulates FOXM1 expression by competitively binding endogenous miR-342-3p in gallbladder cancer.
Wang SH, Ma F, Tang ZH, Wu XC, Cai Q, Zhang MD, Weng MZ, Zhou D, Wang JD, Quan ZW
Journal of experimental & clinical cancer research : CR 2016 Oct 3;35(1):160
Journal of experimental & clinical cancer research : CR 2016 Oct 3;35(1):160
Golgi protein 73 facilitates the interaction of hepatitis C virus NS5A with apolipoprotein E to promote viral particle secretion.
Zhang X, Wang T, Dai X, Zhang Y, Jiang H, Zhang Q, Liu F, Wu K, Liu Y, Zhou H, Wu J
Biochemical and biophysical research communications 2016 Oct 28;479(4):683-689
Biochemical and biophysical research communications 2016 Oct 28;479(4):683-689
Dioscin attenuates gastric ischemia/reperfusion injury through the down-regulation of PKC/ERK1/2 signaling via PKCα and PKCβ2 inhibition.
Hu Y, Tao X, Han X, Xu L, Yin L, Qi Y, Zhao Y, Xu Y, Wang C, Peng J
Chemico-biological interactions 2016 Oct 25;258:234-44
Chemico-biological interactions 2016 Oct 25;258:234-44
Depletion of thymopoietin inhibits proliferation and induces cell cycle arrest/apoptosis in glioblastoma cells.
Zhang L, Wang G, Chen S, Ding J, Ju S, Cao H, Tian H
World journal of surgical oncology 2016 Oct 19;14(1):267
World journal of surgical oncology 2016 Oct 19;14(1):267
Afamin promotes glucose metabolism in papillary thyroid carcinoma.
Shen CT, Wei WJ, Qiu ZL, Song HJ, Luo QY
Molecular and cellular endocrinology 2016 Oct 15;434:108-15
Molecular and cellular endocrinology 2016 Oct 15;434:108-15
Olig2-Targeted G-Protein-Coupled Receptor Gpr17 Regulates Oligodendrocyte Survival in Response to Lysolecithin-Induced Demyelination.
Ou Z, Sun Y, Lin L, You N, Liu X, Li H, Ma Y, Cao L, Han Y, Liu M, Deng Y, Yao L, Lu QR, Chen Y
The Journal of neuroscience : the official journal of the Society for Neuroscience 2016 Oct 12;36(41):10560-10573
The Journal of neuroscience : the official journal of the Society for Neuroscience 2016 Oct 12;36(41):10560-10573
Cleavage and polyadenylation specific factor 4 targets NF-κB/cyclooxygenase-2 signaling to promote lung cancer growth and progression.
Yi C, Wang Y, Zhang C, Xuan Y, Zhao S, Liu T, Li W, Liao Y, Feng X, Hao J, Gao Y, Yu W, Chen Y, Zhang C, Guo W, Tang B, Deng W
Cancer letters 2016 Oct 10;381(1):1-13
Cancer letters 2016 Oct 10;381(1):1-13
25-Hydroxycholesterol impairs endothelial function and vasodilation by uncoupling and inhibiting endothelial nitric oxide synthase.
Ou ZJ, Chen J, Dai WP, Liu X, Yang YK, Li Y, Lin ZB, Wang TT, Wu YY, Su DH, Cheng TP, Wang ZP, Tao J, Ou JS
American journal of physiology. Endocrinology and metabolism 2016 Oct 1;311(4):E781-E790
American journal of physiology. Endocrinology and metabolism 2016 Oct 1;311(4):E781-E790
Tim-4 protects mice against lipopolysaccharide-induced endotoxic shock by suppressing the NF-κB signaling pathway.
Xu L, Zhao P, Xu Y, Gao L, Wang H, Jia X, Ma H, Liang X, Ma C, Gao L
Laboratory investigation; a journal of technical methods and pathology 2016 Nov;96(11):1189-1197
Laboratory investigation; a journal of technical methods and pathology 2016 Nov;96(11):1189-1197
MicroRNA124 Regulated Neurite Elongation by Targeting OSBP.
Gu X, Li A, Liu S, Lin L, Xu S, Zhang P, Li S, Li X, Tian B, Zhu X, Wang X
Molecular neurobiology 2016 Nov;53(9):6388-6396
Molecular neurobiology 2016 Nov;53(9):6388-6396
Cyclooxygenase-2 is associated with malignant phenotypes in human lung cancer.
Li W, Yue W, Wang H, Lai B, Yang X, Zhang C, Wang Y, Gu M
Oncology letters 2016 Nov;12(5):3836-3844
Oncology letters 2016 Nov;12(5):3836-3844
Sargassum fusiforme polysaccharides activate antioxidant defense by promoting Nrf2-dependent cytoprotection and ameliorate stress insult during aging.
Chen P, He D, Zhang Y, Yang S, Chen L, Wang S, Zou H, Liao Z, Zhang X, Wu M
Food & function 2016 Nov 9;7(11):4576-4588
Food & function 2016 Nov 9;7(11):4576-4588
Promotive effects of bone morphogenetic protein 2 on angiogenesis in hepatocarcinoma via multiple signal pathways.
Zuo WH, Zeng P, Chen X, Lu YJ, Li A, Wu JB
Scientific reports 2016 Nov 25;6:37499
Scientific reports 2016 Nov 25;6:37499
NR4A1 Knockdown Suppresses Seizure Activity by Regulating Surface Expression of NR2B.
Zhang Y, Chen G, Gao B, Li Y, Liang S, Wang X, Wang X, Zhu B
Scientific reports 2016 Nov 23;6:37713
Scientific reports 2016 Nov 23;6:37713
Quantitative proteomics reveals molecular mechanism of gamabufotalin and its potential inhibition on Hsp90 in lung cancer.
Zhang L, Yu Z, Wang Y, Wang X, Zhang L, Wang C, Yue Q, Wang X, Deng S, Huo X, Tian X, Huang S, Zhang B, Ma X
Oncotarget 2016 Nov 22;7(47):76551-76564
Oncotarget 2016 Nov 22;7(47):76551-76564
Keap1 hypomorphism protects against ischemic and obstructive kidney disease.
Tan RJ, Chartoumpekis DV, Rush BM, Zhou D, Fu H, Kensler TW, Liu Y
Scientific reports 2016 Nov 2;6:36185
Scientific reports 2016 Nov 2;6:36185
Lithium promotes DNA stability and survival of ischemic retinal neurocytes by upregulating DNA ligase IV.
Yang Y, Wu N, Tian S, Li F, Hu H, Chen P, Cai X, Xu L, Zhang J, Chen Z, Ge J, Yu K, Zhuang J
Cell death & disease 2016 Nov 17;7(11):e2473
Cell death & disease 2016 Nov 17;7(11):e2473
microRNA-23a, -27a and -24 synergistically regulate JAK1/Stat3 cascade and serve as novel therapeutic targets in human acute erythroid leukemia.
Su R, Dong L, Zou D, Zhao H, Ren Y, Li F, Yi P, Li L, Zhu Y, Ma Y, Wang J, Wang F, Yu J
Oncogene 2016 Nov 17;35(46):6001-6014
Oncogene 2016 Nov 17;35(46):6001-6014
Neutrophil extracellular traps are indirectly triggered by lipopolysaccharide and contribute to acute lung injury.
Liu S, Su X, Pan P, Zhang L, Hu Y, Tan H, Wu D, Liu B, Li H, Li H, Li Y, Dai M, Li Y, Hu C, Tsung A
Scientific reports 2016 Nov 16;6:37252
Scientific reports 2016 Nov 16;6:37252
Activation of the RLR/MAVS Signaling Pathway by the L Protein of Mopeia Virus.
Zhang LK, Xin QL, Zhu SL, Wan WW, Wang W, Xiao G
Journal of virology 2016 Nov 15;90(22):10259-10270
Journal of virology 2016 Nov 15;90(22):10259-10270
MicroRNA deep sequencing in two adult stem cell populations identifies miR-501 as a novel regulator of myosin heavy chain during muscle regeneration.
Mizbani A, Luca E, Rushing EJ, Krützfeldt J
Development (Cambridge, England) 2016 Nov 15;143(22):4137-4148
Development (Cambridge, England) 2016 Nov 15;143(22):4137-4148
Phosphorylation of STAT2 on serine-734 negatively regulates the IFN-α-induced antiviral response.
Steen HC, Kotredes KP, Nogusa S, Harris MY, Balachandran S, Gamero AM
Journal of cell science 2016 Nov 15;129(22):4190-4199
Journal of cell science 2016 Nov 15;129(22):4190-4199
17β-Estradiol Inhibites Tumor Necrosis Factor-α Induced Apoptosis of Human Nucleus Pulposus Cells via the PI3K/Akt Pathway.
Wang T, Yang SD, Liu S, Wang H, Liu H, Ding WY
Medical science monitor : international medical journal of experimental and clinical research 2016 Nov 12;22:4312-4322
Medical science monitor : international medical journal of experimental and clinical research 2016 Nov 12;22:4312-4322
Deletion of Pr130 Interrupts Cardiac Development in Zebrafish.
Yang J, Li Z, Gan X, Zhai G, Gao J, Xiong C, Qiu X, Wang X, Yin Z, Zheng F
International journal of molecular sciences 2016 Nov 11;17(11)
International journal of molecular sciences 2016 Nov 11;17(11)
Downregulation of myosin VI reduced cell growth and increased apoptosis in human colorectal cancer.
You W, Tan G, Sheng N, Gong J, Yan J, Chen D, Zhang H, Wang Z
Acta biochimica et biophysica Sinica 2016 May;48(5):430-6
Acta biochimica et biophysica Sinica 2016 May;48(5):430-6
Pristimerin overcomes adriamycin resistance in breast cancer cells through suppressing Akt signaling.
Xie G, Yu X, Liang H, Chen J, Tang X, Wu S, Liao C
Oncology letters 2016 May;11(5):3111-3116
Oncology letters 2016 May;11(5):3111-3116
Downregulation of ATOH8 induced by EBV-encoded LMP1 contributes to the malignant phenotype of nasopharyngeal carcinoma.
Wang Z, Xie J, Yan M, Wang J, Wang X, Zhang J, Zhang Y, Li P, Lei X, Huang Q, Lin S, Guo X, Liu Q
Oncotarget 2016 May 3;7(18):26765-79
Oncotarget 2016 May 3;7(18):26765-79
MicroRNA-24 promotes 3T3-L1 adipocyte differentiation by directly targeting the MAPK7 signaling.
Jin M, Wu Y, Wang J, Chen J, Huang Y, Rao J, Feng C
Biochemical and biophysical research communications 2016 May 20;474(1):76-82
Biochemical and biophysical research communications 2016 May 20;474(1):76-82
RBM4 promotes neuronal differentiation and neurite outgrowth by modulating Numb isoform expression.
Tarn WY, Kuo HC, Yu HI, Liu SW, Tseng CT, Dhananjaya D, Hung KY, Tu CC, Chang SH, Huang GJ, Chiu IM
Molecular biology of the cell 2016 May 15;27(10):1676-83
Molecular biology of the cell 2016 May 15;27(10):1676-83
CGP57380 enhances efficacy of RAD001 in non-small cell lung cancer through abrogating mTOR inhibition-induced phosphorylation of eIF4E and activating mitochondrial apoptotic pathway.
Wen Q, Wang W, Luo J, Chu S, Chen L, Xu L, Zang H, Alnemah MM, Ma J, Fan S
Oncotarget 2016 May 10;7(19):27787-801
Oncotarget 2016 May 10;7(19):27787-801
MiR-146a affects the alteration in myeloid differentiation induced by hydroquinone in human CD34+ hematopoietic progenitor cells and HL-60 cells.
Yuan W, Sun Q, Jiang Y, Zhang X, Chen L, Xie C, Qin F, Chen Y, Lv H, Chen W, Xiao Y
Toxicology research 2016 May 1;5(3):848-858
Toxicology research 2016 May 1;5(3):848-858
Transcription factor Fli-1 positively regulates lipopolysaccharide-induced interleukin-27 production in macrophages.
Gao P, Yuan M, Ma X, Jiang W, Zhu L, Wen M, Xu J, Liu Q, An H
Molecular immunology 2016 Mar;71:184-191
Molecular immunology 2016 Mar;71:184-191
Glutathione S-transferase SlGSTE1 in Spodoptera litura may be associated with feeding adaptation of host plants.
Zou X, Xu Z, Zou H, Liu J, Chen S, Feng Q, Zheng S
Insect biochemistry and molecular biology 2016 Mar;70:32-43
Insect biochemistry and molecular biology 2016 Mar;70:32-43
The protective effect of melatonin on smoke-induced vascular injury in rats and humans: a randomized controlled trial.
Wang Z, Ni L, Wang J, Lu C, Ren M, Han W, Liu C
Journal of pineal research 2016 Mar;60(2):217-27
Journal of pineal research 2016 Mar;60(2):217-27
Akt inhibitor MK-2206 enhances the effect of cisplatin in gastric cancer cells.
Tao K, Yin Y, Shen Q, Chen Y, Li R, Chang W, Bai J, Liu W, Shi L, Zhang P
Biomedical reports 2016 Mar;4(3):365-368
Biomedical reports 2016 Mar;4(3):365-368
Swine TRIM21 restricts FMDV infection via an intracellular neutralization mechanism.
Fan W, Zhang D, Qian P, Qian S, Wu M, Chen H, Li X
Antiviral research 2016 Mar;127:32-40
Antiviral research 2016 Mar;127:32-40
Significance of the NOR1-FOXA1/HDAC2-Slug regulatory network in epithelial-mesenchymal transition of tumor cells.
Wang W, Yi M, Chen S, Li J, Li G, Yang J, Zheng P, Zhang H, Xiong W, McCarthy JB, Li G, Li X, Xiang B
Oncotarget 2016 Mar 29;7(13):16745-59
Oncotarget 2016 Mar 29;7(13):16745-59
Bromodomain-containing protein 7 (BRD7) as a potential tumor suppressor in hepatocellular carcinoma.
Chen CL, Wang Y, Pan QZ, Tang Y, Wang QJ, Pan K, Huang LX, He J, Zhao JJ, Jiang SS, Zhang XF, Zhang HX, Zhou ZQ, Weng de S, Xia JC
Oncotarget 2016 Mar 29;7(13):16248-61
Oncotarget 2016 Mar 29;7(13):16248-61
TGF-β1 activates the canonical NF-κB signaling to promote cell survival and proliferation in dystrophic muscle fibroblasts in vitro.
Ma ZY, Zhong ZG, Qiu MY, Zhong YH, Zhang WX
Biochemical and biophysical research communications 2016 Mar 18;471(4):576-81
Biochemical and biophysical research communications 2016 Mar 18;471(4):576-81
REST alleviates neurotoxic prion peptide-induced synaptic abnormalities, neurofibrillary degeneration and neuronal death partially via LRP6-mediated Wnt-β-catenin signaling.
Song Z, Zhu T, Zhou X, Barrow P, Yang W, Cui Y, Yang L, Zhao D
Oncotarget 2016 Mar 15;7(11):12035-52
Oncotarget 2016 Mar 15;7(11):12035-52
Suppression of prostate cancer progression by cancer cell stemness inhibitor napabucasin.
Zhang Y, Jin Z, Zhou H, Ou X, Xu Y, Li H, Liu C, Li B
Cancer medicine 2016 Jun;5(6):1251-8
Cancer medicine 2016 Jun;5(6):1251-8
A novel conditional gene silencing method using a tumor-specific and heat-inducible siRNA system.
Feng J, Wang X, Liao Y, Feng J, Tang L
Journal of industrial microbiology & biotechnology 2016 Jun;43(6):761-70
Journal of industrial microbiology & biotechnology 2016 Jun;43(6):761-70
Mitigation of tight junction protein dysfunction in lung microvascular endothelial cells with pitavastatin.
Suzuki R, Nakamura Y, Chiba S, Mizuno T, Abe K, Horii Y, Nagashima H, Tanita T, Yamauchi K
Pulmonary pharmacology & therapeutics 2016 Jun;38:27-35
Pulmonary pharmacology & therapeutics 2016 Jun;38:27-35
Oleanolic acid inhibits cell survival and proliferation of prostate cancer cells in vitro and in vivo through the PI3K/Akt pathway.
Li X, Song Y, Zhang P, Zhu H, Chen L, Xiao Y, Xing Y
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2016 Jun;37(6):7599-613
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2016 Jun;37(6):7599-613
Recombinant adeno-associated virus-delivered anginex inhibits angiogenesis and growth of HUVECs by regulating the Akt, JNK and NF-κB signaling pathways.
Ma K, Wang C, Geng Q, Fan Y, Ning J, Yang H, Dong X, Dong D, Guo Y, Wei X, Li E, Wu Y
Oncology reports 2016 Jun;35(6):3505-13
Oncology reports 2016 Jun;35(6):3505-13
Coordinate regulatory osteogenesis effects of icariin, timosaponin B II and ferulic acid from traditional Chinese medicine formulas on UMR-106 osteoblastic cells and osteoblasts in neonatal rat calvaria cultures.
Li M, Zhang ND, Wang Y, Han T, Jiang YP, Rahman K, Qin LP, Xin HL, Zhang QY
Journal of ethnopharmacology 2016 Jun 5;185:120-31
Journal of ethnopharmacology 2016 Jun 5;185:120-31
Downregulation of stathmin 1 in human gallbladder carcinoma inhibits tumor growth in vitro and in vivo.
Wang J, Yao Y, Ming Y, Shen S, Wu N, Liu J, Liu H, Suo T, Pan H, Zhang D, Ding K, Liu H
Scientific reports 2016 Jun 28;6:28833
Scientific reports 2016 Jun 28;6:28833
HuR-regulated lncRNA NEAT1 stability in tumorigenesis and progression of ovarian cancer.
Chai Y, Liu J, Zhang Z, Liu L
Cancer medicine 2016 Jul;5(7):1588-98
Cancer medicine 2016 Jul;5(7):1588-98
Midgut epithelium in molting silkworm: A fine balance among cell growth, differentiation, and survival.
Franzetti E, Casartelli M, D'Antona P, Montali A, Romanelli D, Cappellozza S, Caccia S, Grimaldi A, de Eguileor M, Tettamanti G
Arthropod structure & development 2016 Jul;45(4):368-79
Arthropod structure & development 2016 Jul;45(4):368-79
High TXNDC5 expression predicts poor prognosis in renal cell carcinoma.
Mo R, Peng J, Xiao J, Ma J, Li W, Wang J, Ruan Y, Ma S, Hong Y, Wang C, Gao K, Fan J
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2016 Jul;37(7):9797-806
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2016 Jul;37(7):9797-806
MicroRNA-124 negatively regulates LPS-induced TNF-α production in mouse macrophages by decreasing protein stability.
Sun Y, Qin Z, Li Q, Wan JJ, Cheng MH, Wang PY, Su DF, Yu JG, Liu X
Acta pharmacologica Sinica 2016 Jul;37(7):889-97
Acta pharmacologica Sinica 2016 Jul;37(7):889-97
Berberine in combination with cisplatin suppresses breast cancer cell growth through induction of DNA breaks and caspase-3-dependent apoptosis.
Zhao Y, Jing Z, Li Y, Mao W
Oncology reports 2016 Jul;36(1):567-72
Oncology reports 2016 Jul;36(1):567-72
Malignant gliomas induce and exploit astrocytic mesenchymal-like transition by activating canonical Wnt/β-catenin signaling.
Lu P, Wang Y, Liu X, Wang H, Zhang X, Wang K, Wang Q, Hu R
Medical oncology (Northwood, London, England) 2016 Jul;33(7):66
Medical oncology (Northwood, London, England) 2016 Jul;33(7):66
Comparative Effects of Bile Diversion and Duodenal-Jejunal Bypass on Glucose and Lipid Metabolism in Male Diabetic Rats.
Zhang X, Liu T, Wang Y, Zhong M, Zhang G, Liu S, Wu T, Rayner CK, Hu S
Obesity surgery 2016 Jul;26(7):1565-75
Obesity surgery 2016 Jul;26(7):1565-75
Influence of orally fed a select mixture of Bacillus probiotics on intestinal T-cell migration in weaned MUC4 resistant pigs following Escherichia coli challenge.
Yang GY, Zhu YH, Zhang W, Zhou D, Zhai CC, Wang JF
Veterinary research 2016 Jul 16;47(1):71
Veterinary research 2016 Jul 16;47(1):71
Persisting and Increasing Neutrophil Infiltration Associates with Gastric Carcinogenesis and E-cadherin Downregulation.
Fu H, Ma Y, Yang M, Zhang C, Huang H, Xia Y, Lu L, Jin W, Cui D
Scientific reports 2016 Jul 14;6:29762
Scientific reports 2016 Jul 14;6:29762
Polyhydroxycurcuminoids but not curcumin upregulate neprilysin and can be applied to the prevention of Alzheimer's disease.
Chen PT, Chen ZT, Hou WC, Yu LC, Chen RP
Scientific reports 2016 Jul 13;6:29760
Scientific reports 2016 Jul 13;6:29760
Homologous recombination-dependent repair of telomeric DSBs in proliferating human cells.
Mao P, Liu J, Zhang Z, Zhang H, Liu H, Gao S, Rong YS, Zhao Y
Nature communications 2016 Jul 11;7:12154
Nature communications 2016 Jul 11;7:12154
Total saponins isolated from Radix et Rhizoma Leonticis suppresses tumor cells growth by regulation of PI3K/Akt/mTOR and p38 MAPK pathways.
Zhan Y, Liu R, Wang W, Li J, Yang XO, Zhang Y
Environmental toxicology and pharmacology 2016 Jan;41:39-44
Environmental toxicology and pharmacology 2016 Jan;41:39-44
Loss of TIM50 suppresses proliferation and induces apoptosis in breast cancer.
Gao SP, Sun HF, Jiang HL, Li LD, Hu X, Xu XE, Jin W
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2016 Jan;37(1):1279-87
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2016 Jan;37(1):1279-87
Knockdown of protein phosphatase 5 inhibits ovarian cancer growth in vitro.
Zheng X, Zhang L, Jin B, Zhang F, Zhang D, Cui L
Oncology letters 2016 Jan;11(1):168-172
Oncology letters 2016 Jan;11(1):168-172
DNA Methylation mediated down-regulating of MicroRNA-33b and its role in gastric cancer.
Yin H, Song P, Su R, Yang G, Dong L, Luo M, Wang B, Gong B, Liu C, Song W, Wang F, Ma Y, Zhang J, Wang W, Yu J
Scientific reports 2016 Jan 5;6:18824
Scientific reports 2016 Jan 5;6:18824
Regulation of SCN3B/scn3b by Interleukin 2 (IL-2): IL-2 modulates SCN3B/scn3b transcript expression and increases sodium current in myocardial cells.
Zhao Y, Sun Q, Zeng Z, Li Q, Zhou S, Zhou M, Xue Y, Cheng X, Xia Y, Wang Q, Tu X
BMC cardiovascular disorders 2016 Jan 4;16:1
BMC cardiovascular disorders 2016 Jan 4;16:1
miR-183 regulates autophagy and apoptosis in colorectal cancer through targeting of UVRAG.
Huangfu L, Liang H, Wang G, Su X, Li L, Du Z, Hu M, Dong Y, Bai X, Liu T, Yang B, Shan H
Oncotarget 2016 Jan 26;7(4):4735-45
Oncotarget 2016 Jan 26;7(4):4735-45
A simple multi-well stretching device to induce inflammatory responses of vascular endothelial cells.
Wang J, Fan B, Wei Y, Suo X, Ding Y
Lab on a chip 2016 Jan 21;16(2):360-7
Lab on a chip 2016 Jan 21;16(2):360-7
Differential requirement of bone morphogenetic protein receptors Ia (ALK3) and Ib (ALK6) in early embryonic patterning and neural crest development.
Schille C, Heller J, Schambony A
BMC developmental biology 2016 Jan 19;16:1
BMC developmental biology 2016 Jan 19;16:1
Increased expression of copine VI in patients with refractory epilepsy and a rat model.
Zhu B, Zha J, Long Y, Hu X, Chen G, Wang X
Journal of the neurological sciences 2016 Jan 15;360:30-6
Journal of the neurological sciences 2016 Jan 15;360:30-6
Ginsenoside Rg3 inhibits epithelial-mesenchymal transition (EMT) and invasion of lung cancer by down-regulating FUT4.
Tian L, Shen D, Li X, Shan X, Wang X, Yan Q, Liu J
Oncotarget 2016 Jan 12;7(2):1619-32
Oncotarget 2016 Jan 12;7(2):1619-32
A novel combination of oridonin and valproic acid in enhancement of apoptosis induction of HL-60 leukemia cells.
Shi M, Ren X, Wang X, Wang H, Liu G, Yuan X, Zheng S, Yu L, Pan S, Song G, Guo Q, Li L, Zhang X, Zhang Z, Ding H, Jiang G
International journal of oncology 2016 Feb;48(2):734-46
International journal of oncology 2016 Feb;48(2):734-46
Effect of LYRM1 knockdown on proliferation, apoptosis, differentiation and mitochondrial function in the P19 cell model of cardiac differentiation in vitro.
Chen YM, Li X, Song GX, Liu M, Fan Y, Wu LJ, Li H, Zhang QJ, Liu YQ, Qian LM
Journal of bioenergetics and biomembranes 2016 Feb;48(1):33-41
Journal of bioenergetics and biomembranes 2016 Feb;48(1):33-41
NudC regulates actin dynamics and ciliogenesis by stabilizing cofilin 1.
Zhang C, Zhang W, Lu Y, Yan X, Yan X, Zhu X, Liu W, Yang Y, Zhou T
Cell research 2016 Feb;26(2):239-53
Cell research 2016 Feb;26(2):239-53
Role of KIF2A in the progression and metastasis of human glioma.
Zhang X, Ma C, Wang Q, Liu J, Tian M, Yuan Y, Li X, Qu X
Molecular medicine reports 2016 Feb;13(2):1781-7
Molecular medicine reports 2016 Feb;13(2):1781-7
Nanocomplexes from RGD-modified generation 1.0 polyamidoamine based copolymers used for intravascular gene release to prevent restenosis.
Cao D, Tian S, Yi W, Dai G, Chen J, Feng M, Pan S
Nanomedicine (London, England) 2016 Feb;11(4):359-75
Nanomedicine (London, England) 2016 Feb;11(4):359-75
PGRN promotes migration and invasion of epithelial ovarian cancer cells through an epithelial mesenchymal transition program and the activation of cancer associated fibroblasts.
Dong T, Yang D, Li R, Zhang L, Zhao H, Shen Y, Zhang X, Kong B, Wang L
Experimental and molecular pathology 2016 Feb;100(1):17-25
Experimental and molecular pathology 2016 Feb;100(1):17-25
CREB-binding protein regulates lung cancer growth by targeting MAPK and CPSF4 signaling pathway.
Tang Z, Yu W, Zhang C, Zhao S, Yu Z, Xiao X, Tang R, Xuan Y, Yang W, Hao J, Xu T, Zhang Q, Huang W, Deng W, Guo W
Molecular oncology 2016 Feb;10(2):317-29
Molecular oncology 2016 Feb;10(2):317-29
MicroRNA-372 inhibits endometrial carcinoma development by targeting the expression of the Ras homolog gene family member C (RhoC).
Liu BL, Sun KX, Zong ZH, Chen S, Zhao Y
Oncotarget 2016 Feb 9;7(6):6649-64
Oncotarget 2016 Feb 9;7(6):6649-64
RNF135, RING finger protein, promotes the proliferation of human glioblastoma cells in vivo and in vitro via the ERK pathway.
Liu Y, Wang F, Liu Y, Yao Y, Lv X, Dong B, Li J, Ren S, Yao Y, Xu Y
Scientific reports 2016 Feb 9;6:20642
Scientific reports 2016 Feb 9;6:20642
Decreased TPD52 expression is associated with poor prognosis in primary hepatocellular carcinoma.
Wang Y, Chen CL, Pan QZ, Wu YY, Zhao JJ, Jiang SS, Chao J, Zhang XF, Zhang HX, Zhou ZQ, Tang Y, Huang XQ, Zhang JH, Xia JC
Oncotarget 2016 Feb 2;7(5):6323-34
Oncotarget 2016 Feb 2;7(5):6323-34
Thrombospondin-1 might be a therapeutic target to suppress RB cells by regulating the DNA double-strand breaks repair.
Chen P, Yu N, Zhang Z, Zhang P, Yang Y, Wu N, Xu L, Zhang J, Ge J, Yu K, Zhuang J
Oncotarget 2016 Feb 2;7(5):6105-20
Oncotarget 2016 Feb 2;7(5):6105-20
Lactobacillus rhamnosus GR-1 Ameliorates Escherichia coli-Induced Inflammation and Cell Damage via Attenuation of ASC-Independent NLRP3 Inflammasome Activation.
Wu Q, Liu MC, Yang J, Wang JF, Zhu YH
Applied and environmental microbiology 2016 Feb 15;82(4):1173-1182
Applied and environmental microbiology 2016 Feb 15;82(4):1173-1182
DLX3 negatively regulates osteoclastic differentiation through microRNA-124.
Zhao N, Han D, Liu Y, Li Y, Zeng L, Wang Y, Feng H
Experimental cell research 2016 Feb 15;341(2):166-76
Experimental cell research 2016 Feb 15;341(2):166-76
Mammalian cells lacking either the cotranslational or posttranslocational oligosaccharyltransferase complex display substrate-dependent defects in asparagine linked glycosylation.
Cherepanova NA, Gilmore R
Scientific reports 2016 Feb 11;6:20946
Scientific reports 2016 Feb 11;6:20946
Effects of total flavonoids from Drynariae Rhizoma prevent bone loss in vivo and in vitro.
Song SH, Zhai YK, Li CQ, Yu Q, Lu Y, Zhang Y, Hua WP, Wang ZZ, Shang P
Bone reports 2016 Dec;5:262-273
Bone reports 2016 Dec;5:262-273
Life-cycle exposure to BDE-47 results in thyroid endocrine disruption to adults and offsprings of zebrafish (Danio rerio).
Zhao X, Ren X, Ren B, Luo Z, Zhu R
Environmental toxicology and pharmacology 2016 Dec;48:157-167
Environmental toxicology and pharmacology 2016 Dec;48:157-167
Angelicin inhibits human lung carcinoma A549 cell growth and migration through regulating JNK and ERK pathways.
Li G, He Y, Yao J, Huang C, Song X, Deng Y, Xie S, Ren J, Jin M, Liu H
Oncology reports 2016 Dec;36(6):3504-3512
Oncology reports 2016 Dec;36(6):3504-3512
Developmental regulation of CYP3A4 and CYP3A7 in Chinese Han population.
He H, Nie YL, Li JF, Meng XG, Yang WH, Chen YL, Wang SJ, Ma X, Kan QC, Zhang LR
Drug metabolism and pharmacokinetics 2016 Dec;31(6):433-444
Drug metabolism and pharmacokinetics 2016 Dec;31(6):433-444
The lncRNA MALAT1 functions as a competing endogenous RNA to regulate MCL-1 expression by sponging miR-363-3p in gallbladder cancer.
Wang SH, Zhang WJ, Wu XC, Weng MZ, Zhang MD, Cai Q, Zhou D, Wang JD, Quan ZW
Journal of cellular and molecular medicine 2016 Dec;20(12):2299-2308
Journal of cellular and molecular medicine 2016 Dec;20(12):2299-2308
Oligosaccharyltransferase inhibition induces senescence in RTK-driven tumor cells.
Lopez-Sambrooks C, Shrimal S, Khodier C, Flaherty DP, Rinis N, Charest JC, Gao N, Zhao P, Wells L, Lewis TA, Lehrman MA, Gilmore R, Golden JE, Contessa JN
Nature chemical biology 2016 Dec;12(12):1023-1030
Nature chemical biology 2016 Dec;12(12):1023-1030
Interaction between endogenous carbon monoxide and hydrogen sulfide in the mechanism of gastroprotection against acute aspirin-induced gastric damage.
Magierowski M, Magierowska K, Hubalewska-Mazgaj M, Adamski J, Bakalarz D, Sliwowski Z, Pajdo R, Kwiecien S, Brzozowski T
Pharmacological research 2016 Dec;114:235-250
Pharmacological research 2016 Dec;114:235-250
Vam3 ameliorates total body irradiation-induced hematopoietic system injury partly by regulating the expression of Nrf2-targeted genes.
Zhang J, Xue X, Han X, Yao C, Lu L, Li D, Hou Q, Miao W, Meng A, Fan S
Free radical biology & medicine 2016 Dec;101:455-464
Free radical biology & medicine 2016 Dec;101:455-464
Repression of CDKN2C caused by PML/RARα binding promotes the proliferation and differentiation block in acute promyelocytic leukemia.
Wang X, Tan Y, Li Y, Li J, Jin W, Wang K
Frontiers of medicine 2016 Dec;10(4):420-429
Frontiers of medicine 2016 Dec;10(4):420-429
Senescence: novel insight into DLX3 mutations leading to enhanced bone formation in Tricho-Dento-Osseous syndrome.
Zhao N, Han D, Liu H, Li Y, Wong SW, Cao Z, Xu J, Zhang X, Cai T, Wang Y, Feng H
Scientific reports 2016 Dec 7;6:38680
Scientific reports 2016 Dec 7;6:38680
Rab8a/Rab11a regulate intercellular communications between neural cells via tunneling nanotubes.
Zhu H, Xue C, Xu X, Guo Y, Li X, Lu J, Ju S, Wang Y, Cao Z, Gu X
Cell death & disease 2016 Dec 22;7(12):e2523
Cell death & disease 2016 Dec 22;7(12):e2523
Elevated expression of ZNF217 promotes prostate cancer growth by restraining ferroportin-conducted iron egress.
Jiang X, Zhang C, Qi S, Guo S, Chen Y, Du E, Zhang H, Wang X, Liu R, Qiao B, Yang K, Zhang Z, Xu Y
Oncotarget 2016 Dec 20;7(51):84893-84906
Oncotarget 2016 Dec 20;7(51):84893-84906
Unc-5 homolog B (UNC5B) is one of the key downstream targets of N-α-Acetyltransferase 10 (Naa10).
Xu H, Han Y, Liu B, Li R
Scientific reports 2016 Dec 2;6:38508
Scientific reports 2016 Dec 2;6:38508
Up-regulation of granzyme B and perforin by staphylococcal enterotoxin C2 mutant induces enhanced cytotoxicity in Hepa1-6 cells.
Zhang G, Xu M, Zhang H, Song Y, Wang J, Zhang C
Toxicology and applied pharmacology 2016 Dec 15;313:1-9
Toxicology and applied pharmacology 2016 Dec 15;313:1-9
Attribution of NKG2DL to the inhibition of early stage allogeneic tumors in mice.
Hua L, Fang M, Dong B, Guo S, Cui C, Liu J, Yao Y, Xiao Y, Li X, Ren Y, Meng X, Hao X, Zhao P, Song Y, Wang L, Yu Y
Oncotarget 2016 Dec 13;7(50):82369-82383
Oncotarget 2016 Dec 13;7(50):82369-82383
ERK-mediated NF-κB activation through ASIC1 in response to acidosis.
Chen B, Liu J, Ho TT, Ding X, Mo YY
Oncogenesis 2016 Dec 12;5(12):e279
Oncogenesis 2016 Dec 12;5(12):e279
Growth Differentiation Factor-15-Induced Contractile Activity and Extracellular Matrix Production in Human Trabecular Meshwork Cells.
Muralidharan AR, Maddala R, Skiba NP, Rao PV
Investigative ophthalmology & visual science 2016 Dec 1;57(15):6482-6495
Investigative ophthalmology & visual science 2016 Dec 1;57(15):6482-6495
Myeloid cells are capable of synthesizing aldosterone to exacerbate damage in muscular dystrophy.
Chadwick JA, Swager SA, Lowe J, Welc SS, Tidball JG, Gomez-Sanchez CE, Gomez-Sanchez EP, Rafael-Fortney JA
Human molecular genetics 2016 Dec 1;25(23):5167-5177
Human molecular genetics 2016 Dec 1;25(23):5167-5177
Exercise preconditioning reduces neonatal incision surgery-induced enhanced hyperalgesia via inhibition of P38 mitogen-activated protein kinase and IL-1β, TNF-α release.
Gong X, Jiang J, Zhang M
International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience 2016 Aug;52:46-54
International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience 2016 Aug;52:46-54
Low level of FOXL1 indicates a worse prognosis for gastric cancer patients.
Ertao Z, Jianhui C, Chuangqi C, Changjiang Q, Sile C, Yulong H, Shirong C, Hui W
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2016 Aug;37(8):11331-7
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2016 Aug;37(8):11331-7
Dynamic distributions of tumor necrosis factor-alpha and its receptors in the red nucleus of rats with spared nerve injury.
Wang J, Ding CP, Yu J, Zeng XY, Han SP, Wang JY
Neuropathology : official journal of the Japanese Society of Neuropathology 2016 Aug;36(4):346-53
Neuropathology : official journal of the Japanese Society of Neuropathology 2016 Aug;36(4):346-53
LINE-1 gene hypomethylation and p16 gene hypermethylation in HepG2 cells induced by low-dose and long-term triclosan exposure: The role of hydroxyl group.
Zeng L, Ma H, Pan S, You J, Zhang G, Yu Z, Sheng G, Fu J
Toxicology in vitro : an international journal published in association with BIBRA 2016 Aug;34:35-44
Toxicology in vitro : an international journal published in association with BIBRA 2016 Aug;34:35-44
Improvements of Glucose and Lipid Metabolism After Jejuno-ileal Circuit Procedure in a Non-obese Diabetic Rat Model.
Wang Y, Zhang X, Zhong M, Liu T, Zhang G, Liu S, Guo W, Wei M, He Q, Sun D, Hu S
Obesity surgery 2016 Aug;26(8):1768-76
Obesity surgery 2016 Aug;26(8):1768-76
NRAGE is involved in homologous recombination repair to resist the DNA-damaging chemotherapy and composes a ternary complex with RNF8-BARD1 to promote cell survival in squamous esophageal tumorigenesis.
Yang Q, Pan Q, Li C, Xu Y, Wen C, Sun F
Cell death and differentiation 2016 Aug;23(8):1406-16
Cell death and differentiation 2016 Aug;23(8):1406-16
Inhibition of the glucocorticoid receptor results in an enhanced miR-99a/100-mediated radiation response in stem-like cells from human prostate cancers.
Rane JK, Erb HH, Nappo G, Mann VM, Simms MS, Collins AT, Visakorpi T, Maitland NJ
Oncotarget 2016 Aug 9;7(32):51965-51980
Oncotarget 2016 Aug 9;7(32):51965-51980
Paper-based microreactor array for rapid screening of cell signaling cascades.
Huang CH, Lei KF, Tsang NM
Lab on a chip 2016 Aug 7;16(15):2911-20
Lab on a chip 2016 Aug 7;16(15):2911-20
The long noncoding RNA ASNR regulates degradation of Bcl-2 mRNA through its interaction with AUF1.
Chen J, Liu L, Wei G, Wu W, Luo H, Yuan J, Luo J, Chen R
Scientific reports 2016 Aug 31;6:32189
Scientific reports 2016 Aug 31;6:32189
Porcine reproductive and respiratory syndrome virus triggers mitochondrial fission and mitophagy to attenuate apoptosis.
Li S, Wang J, Zhou A, Khan FA, Hu L, Zhang S
Oncotarget 2016 Aug 30;7(35):56002-56012
Oncotarget 2016 Aug 30;7(35):56002-56012
Long non-coding RNA AFAP1-AS1 facilitates tumor growth and promotes metastasis in colorectal cancer.
Han X, Wang L, Ning Y, Li S, Wang Z
Biological research 2016 Aug 30;49(1):36
Biological research 2016 Aug 30;49(1):36
EWSR1 regulates mitosis by dynamically influencing microtubule acetylation.
Wang YL, Chen H, Zhan YQ, Yin RH, Li CY, Ge CH, Yu M, Yang XM
Cell cycle (Georgetown, Tex.) 2016 Aug 17;15(16):2202-2215
Cell cycle (Georgetown, Tex.) 2016 Aug 17;15(16):2202-2215
USP14 regulates autophagy by suppressing K63 ubiquitination of Beclin 1.
Xu D, Shan B, Sun H, Xiao J, Zhu K, Xie X, Li X, Liang W, Lu X, Qian L, Yuan J
Genes & development 2016 Aug 1;30(15):1718-30
Genes & development 2016 Aug 1;30(15):1718-30
Constitutive translation of human α-synuclein is mediated by the 5'-untranslated region.
Koukouraki P, Doxakis E
Open biology 2016 Apr;6(4):160022
Open biology 2016 Apr;6(4):160022
Upregulation of GSK3β Contributes to Brain Disorders in Elderly REGγ-knockout Mice.
Lv Y, Meng B, Dong H, Jing T, Wu N, Yang Y, Huang L, Moses RE, O'Malley BW, Mei B, Li X
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2016 Apr;41(5):1340-9
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2016 Apr;41(5):1340-9
Interplay of autophagy and apoptosis during PRRSV infection of Marc145 cell.
Li S, Zhou A, Wang J, Zhang S
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases 2016 Apr;39:51-54
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases 2016 Apr;39:51-54
Down-regulation of ribosomal protein S15A inhibits proliferation of human glioblastoma cells in vivo and in vitro via AKT pathway.
Yao Y, Liu Y, Lv X, Dong B, Wang F, Li J, Zhang Q, Xu R, Xu Y
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2016 Apr;37(4):4979-90
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2016 Apr;37(4):4979-90
Lead Inhibits Human Sperm Functions by Reducing the Levels of Intracellular Calcium, cAMP, and Tyrosine Phosphorylation.
He Y, Zou Q, Chen H, Weng S, Luo T, Zeng X
The Tohoku journal of experimental medicine 2016 Apr;238(4):295-303
The Tohoku journal of experimental medicine 2016 Apr;238(4):295-303
Altered expression of miR-125a-5p in thymoma-associated myasthenia gravis and its down-regulation of foxp3 expression in Jurkat cells.
Li J, Qiu D, Chen Z, Du W, Liu J, Mo X
Immunology letters 2016 Apr;172:47-55
Immunology letters 2016 Apr;172:47-55
Lentivirus-mediated knockdown of CTDP1 inhibits lung cancer cell growth in vitro.
Zhong R, Ge X, Chu T, Teng J, Yan B, Pei J, Jiang L, Zhong H, Han B
Journal of cancer research and clinical oncology 2016 Apr;142(4):723-32
Journal of cancer research and clinical oncology 2016 Apr;142(4):723-32
Downregulation of VEGF and upregulation of TL1A expression induce HUVEC apoptosis in response to high glucose stimuli.
Yu M, Lu G, Zhu X, Huang Z, Feng C, Fang R, Wang Y, Gao X
Molecular medicine reports 2016 Apr;13(4):3265-72
Molecular medicine reports 2016 Apr;13(4):3265-72
β-Arrestins promote podocyte injury by inhibition of autophagy in diabetic nephropathy.
Liu J, Li QX, Wang XJ, Zhang C, Duan YQ, Wang ZY, Zhang Y, Yu X, Li NJ, Sun JP, Yi F
Cell death & disease 2016 Apr 7;7:e2183
Cell death & disease 2016 Apr 7;7:e2183
Linc-RoR promotes c-Myc expression through hnRNP I and AUF1.
Huang J, Zhang A, Ho TT, Zhang Z, Zhou N, Ding X, Zhang X, Xu M, Mo YY
Nucleic acids research 2016 Apr 20;44(7):3059-69
Nucleic acids research 2016 Apr 20;44(7):3059-69
Inhibition on Apoptosis Induced by Elevated Hydrostatic Pressure in Retinal Ganglion Cell-5 via Laminin Upregulating β1-integrin/Focal Adhesion Kinase/Protein Kinase B Signaling Pathway.
Li Y, Chen YM, Sun MM, Guo XD, Wang YC, Zhang ZZ
Chinese medical journal 2016 Apr 20;129(8):976-83
Chinese medical journal 2016 Apr 20;129(8):976-83
Autocrine Sonic hedgehog signaling promotes gastric cancer proliferation through induction of phospholipase Cγ1 and the ERK1/2 pathway.
Ertao Z, Jianhui C, Chuangqi C, Changjiang Q, Sile C, Yulong H, Hui W, Shirong C
Journal of experimental & clinical cancer research : CR 2016 Apr 2;35:63
Journal of experimental & clinical cancer research : CR 2016 Apr 2;35:63
A Point Mutation in the Exon Junction Complex Factor Y14 Disrupts Its Function in mRNA Cap Binding and Translation Enhancement.
Chuang TW, Lee KM, Lou YC, Lu CC, Tarn WY
The Journal of biological chemistry 2016 Apr 15;291(16):8565-74
The Journal of biological chemistry 2016 Apr 15;291(16):8565-74
Comparative proteomic study of the response to hypoxia in the muscle of oriental river prawn (Macrobrachium nipponense).
Sun S, Xuan F, Fu H, Ge X, Zhu J, Qiao H, Jin S, Zhang Y
Journal of proteomics 2016 Apr 14;138:115-23
Journal of proteomics 2016 Apr 14;138:115-23
PACE4 regulates apoptosis in human prostate cancer cells via endoplasmic reticulum stress and mitochondrial signaling pathways.
Yao Z, Sun B, Hong Q, Yan J, Mu D, Li J, Sheng H, Guo H
Drug design, development and therapy 2015;9:5911-23
Drug design, development and therapy 2015;9:5911-23
Trefoil factor 1 elevates the malignant phenotype of mucinous ovarian cancer cell through Wnt/β-catenin signaling.
Zhao S, Ma Y, Huang X
International journal of clinical and experimental pathology 2015;8(9):10412-9
International journal of clinical and experimental pathology 2015;8(9):10412-9
Complement factors C1q, C3 and C5b-9 in the posterior sclera of guinea pigs with negative lens-defocused myopia.
Gao TT, Long Q, Yang X
International journal of ophthalmology 2015;8(4):675-80
International journal of ophthalmology 2015;8(4):675-80
Regulative Effect of Nampt on Tumor Progression and Cell Viability in Human Colorectal Cancer.
Lv X, Zhang L, Zhu Y, Said HM, Shi J, Xu G
Journal of Cancer 2015;6(9):849-58
Journal of Cancer 2015;6(9):849-58
Highly expressed UNC119 promotes hepatocellular carcinoma cell proliferation through Wnt/β-catenin signaling and predicts a poor prognosis.
Lei B, Chai W, Wang Z, Liu R
American journal of cancer research 2015;5(10):3123-34
American journal of cancer research 2015;5(10):3123-34
Huaier Aqueous Extract Induces Hepatocellular Carcinoma Cells Arrest in S Phase via JNK Signaling Pathway.
Zhang C, Zhang J, Li X, Sun N, Yu R, Zhao B, Yu D, Cheng Y, Liu Y
Evidence-based complementary and alternative medicine : eCAM 2015;2015:171356
Evidence-based complementary and alternative medicine : eCAM 2015;2015:171356
A Selected Lactobacillus rhamnosus Strain Promotes EGFR-Independent Akt Activation in an Enterotoxigenic Escherichia coli K88-Infected IPEC-J2 Cell Model.
Zhang W, Zhu YH, Yang JC, Yang GY, Zhou D, Wang JF
PloS one 2015;10(4):e0125717
PloS one 2015;10(4):e0125717
Down-Regulation of NDUFB9 Promotes Breast Cancer Cell Proliferation, Metastasis by Mediating Mitochondrial Metabolism.
Li LD, Sun HF, Liu XX, Gao SP, Jiang HL, Hu X, Jin W
PloS one 2015;10(12):e0144441
PloS one 2015;10(12):e0144441
Effects of Carbon Nanotube Environmental Dispersion on an Aquatic Invertebrate, Hirudo medicinalis.
Girardello R, Tasselli S, Baranzini N, Valvassori R, de Eguileor M, Grimaldi A
PloS one 2015;10(12):e0144361
PloS one 2015;10(12):e0144361
CRISPR/Cas9 Promotes Functional Study of Testis Specific X-Linked Gene In Vivo.
Li M, Huang R, Jiang X, Chen Y, Zhang Z, Zhang X, Liang P, Zhan S, Cao S, Songyang Z, Huang J
PloS one 2015;10(11):e0143148
PloS one 2015;10(11):e0143148
Endothelial cell-targeted pVEGF165 polyplex plays a pivotal role in inhibiting intimal thickening after vascular injury.
Tian S, Cao D, Zou H, Bai F, Wang Z, Pan S, Feng M
International journal of nanomedicine 2015;10:5751-68
International journal of nanomedicine 2015;10:5751-68
Circulating microparticles from patients with valvular heart disease and cardiac surgery inhibit endothelium-dependent vasodilation.
Fu L, Hu XX, Lin ZB, Chang FJ, Ou ZJ, Wang ZP, Ou JS
The Journal of thoracic and cardiovascular surgery 2015 Sep;150(3):666-72
The Journal of thoracic and cardiovascular surgery 2015 Sep;150(3):666-72
Effect of Huaier on the proliferation and apoptosis of human gastric cancer cells through modulation of the PI3K/AKT signaling pathway.
Xie HX, Xu ZY, Tang JN, DU YA, Huang L, Yu PF, Cheng XD
Experimental and therapeutic medicine 2015 Sep;10(3):1212-1218
Experimental and therapeutic medicine 2015 Sep;10(3):1212-1218
Phase transition of spindle-associated protein regulate spindle apparatus assembly.
Jiang H, Wang S, Huang Y, He X, Cui H, Zhu X, Zheng Y
Cell 2015 Sep 24;163(1):108-22
Cell 2015 Sep 24;163(1):108-22
SUMOylation at K707 of DGCR8 controls direct function of primary microRNA.
Zhu C, Chen C, Huang J, Zhang H, Zhao X, Deng R, Dou J, Jin H, Chen R, Xu M, Chen Q, Wang Y, Yu J
Nucleic acids research 2015 Sep 18;43(16):7945-60
Nucleic acids research 2015 Sep 18;43(16):7945-60
Prosaposin facilitates sortilin-independent lysosomal trafficking of progranulin.
Zhou X, Sun L, Bastos de Oliveira F, Qi X, Brown WJ, Smolka MB, Sun Y, Hu F
The Journal of cell biology 2015 Sep 14;210(6):991-1002
The Journal of cell biology 2015 Sep 14;210(6):991-1002
Identification of cellular microRNA-136 as a dual regulator of RIG-I-mediated innate immunity that antagonizes H5N1 IAV replication in A549 cells.
Zhao L, Zhu J, Zhou H, Zhao Z, Zou Z, Liu X, Lin X, Zhang X, Deng X, Wang R, Chen H, Jin M
Scientific reports 2015 Oct 9;5:14991
Scientific reports 2015 Oct 9;5:14991
Protein kinase CK2α catalytic subunit is overexpressed and serves as an unfavorable prognostic marker in primary hepatocellular carcinoma.
Zhang HX, Jiang SS, Zhang XF, Zhou ZQ, Pan QZ, Chen CL, Zhao JJ, Tang Y, Xia JC, Weng DS
Oncotarget 2015 Oct 27;6(33):34800-17
Oncotarget 2015 Oct 27;6(33):34800-17
FGF1-FGFR1 axis promotes tongue squamous cell carcinoma (TSCC) metastasis through epithelial-mesenchymal transition (EMT).
Jiao J, Zhao X, Liang Y, Tang D, Pan C
Biochemical and biophysical research communications 2015 Oct 23;466(3):327-32
Biochemical and biophysical research communications 2015 Oct 23;466(3):327-32
BPTF promotes tumor growth and predicts poor prognosis in lung adenocarcinomas.
Dai M, Lu JJ, Guo W, Yu W, Wang Q, Tang R, Tang Z, Xiao Y, Li Z, Sun W, Sun X, Qin Y, Huang W, Deng WG, Wu T
Oncotarget 2015 Oct 20;6(32):33878-92
Oncotarget 2015 Oct 20;6(32):33878-92
Neuroleukin/Autocrine Motility Factor Receptor Pathway Promotes Proliferation of Articular Chondrocytes through Activation of AKT and Smad2/3.
Tian K, Zhong W, Zheng X, Zhang J, Liu P, Zhang W, Liu H
Scientific reports 2015 Oct 13;5:15101
Scientific reports 2015 Oct 13;5:15101
RanGTP aids anaphase entry through Ubr5-mediated protein turnover.
Jiang H, He X, Feng D, Zhu X, Zheng Y
The Journal of cell biology 2015 Oct 12;211(1):7-18
The Journal of cell biology 2015 Oct 12;211(1):7-18
FOXL2 down-regulates vitellogenin expression at mature stage in Eriocheir sinensis.
Li Q, Xie J, He L, Wang Y, Yang H, Duan Z, Wang Q
Bioscience reports 2015 Oct 1;35(6)
Bioscience reports 2015 Oct 1;35(6)
G-protein-coupled receptor 137 accelerates proliferation of urinary bladder cancer cells in vitro.
Du Y, Bi W, Zhang F, Wu W, Xia S, Liu H
Biotechnology and applied biochemistry 2015 Nov-Dec;62(6):855-60
Biotechnology and applied biochemistry 2015 Nov-Dec;62(6):855-60
MiR542-3p Regulates the Epithelial-Mesenchymal Transition by Directly Targeting BMP7 in NRK52e.
Liu Z, Zhou Y, Yuan Y, Nie F, Peng R, Li Q, Lyu Z, Mao Z, Huang L, Zhou L, Li Y, Hao J, Ni D, Jin Q, Long Y, Ju P, Yu W, Liu J, Hu Y, Zhou Q
International journal of molecular sciences 2015 Nov 24;16(11):27945-55
International journal of molecular sciences 2015 Nov 24;16(11):27945-55
Phosphorylation and activation of ubiquitin-specific protease-14 by Akt regulates the ubiquitin-proteasome system.
Xu D, Shan B, Lee BH, Zhu K, Zhang T, Sun H, Liu M, Shi L, Liang W, Qian L, Xiao J, Wang L, Pan L, Finley D, Yuan J
eLife 2015 Nov 2;4:e10510
eLife 2015 Nov 2;4:e10510
Encephalomyocarditis Virus 3C Protease Relieves TRAF Family Member-associated NF-κB Activator (TANK) Inhibitory Effect on TRAF6-mediated NF-κB Signaling through Cleavage of TANK.
Huang L, Liu Q, Zhang L, Zhang Q, Hu L, Li C, Wang S, Li J, Zhang Y, Yu H, Wang Y, Zhong Z, Xiong T, Xia X, Wang X, Yu L, Deng G, Cai X, Cui S, Weng C
The Journal of biological chemistry 2015 Nov 13;290(46):27618-32
The Journal of biological chemistry 2015 Nov 13;290(46):27618-32
Co-expression of mitosis-regulating genes contributes to malignant progression and prognosis in oligodendrogliomas.
Liu Y, Hu H, Zhang C, Wang H, Zhang W, Wang Z, Li M, Zhang W, Zhou D, Jiang T
Oncotarget 2015 Nov 10;6(35):38257-69
Oncotarget 2015 Nov 10;6(35):38257-69
Dental Abnormalities Caused by Novel Compound Heterozygous CTSK Mutations.
Xue Y, Wang L, Xia D, Li Q, Gao S, Dong M, Cai T, Shi S, He L, Hu K, Mao T, Duan X
Journal of dental research 2015 May;94(5):674-81
Journal of dental research 2015 May;94(5):674-81
Vav3 oncogene is upregulated and a poor prognostic factor in breast cancer patients.
Chen X, Chen SI, Liu XA, Zhou WB, Ma RR, Chen L
Oncology letters 2015 May;9(5):2143-2148
Oncology letters 2015 May;9(5):2143-2148
Microgravity activates p38 MAPK-C/EBPβ pathway to regulate the expression of arginase and inflammatory cytokines in macrophages.
Wang C, Chen H, Luo H, Zhu L, Zhao Y, Tian H, Wang R, Shang P, Zhao Y
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2015 May;64(5):303-11
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2015 May;64(5):303-11
Mitosis. Microtubule detyrosination guides chromosomes during mitosis.
Barisic M, Silva e Sousa R, Tripathy SK, Magiera MM, Zaytsev AV, Pereira AL, Janke C, Grishchuk EL, Maiato H
Science (New York, N.Y.) 2015 May 15;348(6236):799-803
Science (New York, N.Y.) 2015 May 15;348(6236):799-803
HAP1 helps to regulate actin-based transport of insulin-containing granules in pancreatic β cells.
Wang Z, Peng T, Wu H, He J, Li H
Histochemistry and cell biology 2015 Jul;144(1):39-48
Histochemistry and cell biology 2015 Jul;144(1):39-48
MNRR1 (formerly CHCHD2) is a bi-organellar regulator of mitochondrial metabolism.
Aras S, Bai M, Lee I, Springett R, Hüttemann M, Grossman LI
Mitochondrion 2015 Jan;20:43-51
Mitochondrion 2015 Jan;20:43-51
Proteomic profile in Perna viridis after exposed to Prorocentrum lima, a dinoflagellate producing DSP toxins.
Huang L, Zou Y, Weng HW, Li HY, Liu JS, Yang WD
Environmental pollution (Barking, Essex : 1987) 2015 Jan;196:350-7
Environmental pollution (Barking, Essex : 1987) 2015 Jan;196:350-7
DNA methylation downregulated mir-10b acts as a tumor suppressor in gastric cancer.
Li Z, Lei H, Luo M, Wang Y, Dong L, Ma Y, Liu C, Song W, Wang F, Zhang J, Shen J, Yu J
Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association 2015 Jan;18(1):43-54
Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association 2015 Jan;18(1):43-54
Toward operative in vivo fluorescence imaging of the c-Met proto-oncogene for personalization of therapy in ovarian cancer.
Liu S, Zheng Y, Volpi D, El-Kasti M, Klotz D, Tullis I, Henricks A, Campo L, Myers K, Laios A, Thomas P, Ng T, Dhar S, Becker C, Vojnovic B, Ahmed AA
Cancer 2015 Jan 15;121(2):202-13
Cancer 2015 Jan 15;121(2):202-13
Lentivirus-mediated silencing of SCIN inhibits proliferation of human lung carcinoma cells.
Liu H, Shi D, Liu T, Yu Z, Zhou C
Gene 2015 Jan 1;554(1):32-9
Gene 2015 Jan 1;554(1):32-9
Novel function of PITH domain-containing 1 as an activator of internal ribosomal entry site to enhance RUNX1 expression and promote megakaryocyte differentiation.
Lu B, Sun X, Chen Y, Jin Q, Liang Q, Liu S, Li Y, Zhou Y, Li W, Huang Z
Cellular and molecular life sciences : CMLS 2015 Feb;72(4):821-32
Cellular and molecular life sciences : CMLS 2015 Feb;72(4):821-32
Annexin A3 as a potential target for immunotherapy of liver cancer stem-like cells.
Pan QZ, Pan K, Wang QJ, Weng DS, Zhao JJ, Zheng HX, Zhang XF, Jiang SS, Lv L, Tang Y, Li YQ, He J, Liu Q, Chen CL, Zhang HX, Xia JC
Stem cells (Dayton, Ohio) 2015 Feb;33(2):354-66
Stem cells (Dayton, Ohio) 2015 Feb;33(2):354-66
Human mammary microenvironment better regulates the biology of human breast cancer in humanized mouse model.
Zheng MJ, Wang J, Xu L, Zha XM, Zhao Y, Ling LJ, Wang S
Medical oncology (Northwood, London, England) 2015 Feb;32(2):427
Medical oncology (Northwood, London, England) 2015 Feb;32(2):427
Potent effects of the total saponins from Dioscorea nipponica Makino against streptozotocin-induced type 2 diabetes mellitus in rats.
Yu H, Zheng L, Xu L, Yin L, Lin Y, Li H, Liu K, Peng J
Phytotherapy research : PTR 2015 Feb;29(2):228-40
Phytotherapy research : PTR 2015 Feb;29(2):228-40
Moesin and myosin phosphatase confine neutrophil orientation in a chemotactic gradient.
Liu X, Yang T, Suzuki K, Tsukita S, Ishii M, Zhou S, Wang G, Cao L, Qian F, Taylor S, Oh MJ, Levitan I, Ye RD, Carnegie GK, Zhao Y, Malik AB, Xu J
The Journal of experimental medicine 2015 Feb 9;212(2):267-80
The Journal of experimental medicine 2015 Feb 9;212(2):267-80
Targeting non-coding RNAs with the CRISPR/Cas9 system in human cell lines.
Ho TT, Zhou N, Huang J, Koirala P, Xu M, Fung R, Wu F, Mo YY
Nucleic acids research 2015 Feb 18;43(3):e17
Nucleic acids research 2015 Feb 18;43(3):e17
The Energy Metabolism in Caenorhabditis elegans under The Extremely Low-Frequency Electromagnetic Field Exposure.
Shi Z, Yu H, Sun Y, Yang C, Lian H, Cai P
Scientific reports 2015 Feb 16;5:8471
Scientific reports 2015 Feb 16;5:8471
Flavivirus Infection Impairs Peroxisome Biogenesis and Early Antiviral Signaling.
You J, Hou S, Malik-Soni N, Xu Z, Kumar A, Rachubinski RA, Frappier L, Hobman TC
Journal of virology 2015 Dec;89(24):12349-61
Journal of virology 2015 Dec;89(24):12349-61
Erythropoietin Protects Retinal Cells in Diabetic Rats Through Upregulating ZnT8 via Activating ERK Pathway and Inhibiting HIF-1α Expression.
Xu G, Kang D, Zhang C, Lou H, Sun C, Yang Q, Lu L, Xu GT, Zhang J, Wang F
Investigative ophthalmology & visual science 2015 Dec;56(13):8166-78
Investigative ophthalmology & visual science 2015 Dec;56(13):8166-78
Tumor necrosis factor α induces myofibroblast differentiation in human tongue cancer and promotes invasiveness and angiogenesis via secretion of stromal cell-derived factor-1.
Zhou B, Zhuang XM, Wang YY, Lin ZY, Zhang DM, Fan S, Li JS, Chen WL
Oral oncology 2015 Dec;51(12):1095-102
Oral oncology 2015 Dec;51(12):1095-102
Protection of seven dibenzocyclooctadiene lignans from Schisandra chinensis against serum and glucose deprivation injury in SH-SY5Y cells.
E Q, Tang M, Zhang X, Shi Y, Wang D, Gu Y, Li S, Liang X, Wang Z, Wang C
Cell biology international 2015 Dec;39(12):1418-24
Cell biology international 2015 Dec;39(12):1418-24
Cancer-testis antigen MAGE-C2 binds Rbx1 and inhibits ubiquitin ligase-mediated turnover of cyclin E.
Hao J, Song X, Wang J, Guo C, Li Y, Li B, Zhang Y, Yin Y
Oncotarget 2015 Dec 8;6(39):42028-39
Oncotarget 2015 Dec 8;6(39):42028-39
MicroRNA-186 induces sensitivity of ovarian cancer cells to paclitaxel and cisplatin by targeting ABCB1.
Sun KX, Jiao JW, Chen S, Liu BL, Zhao Y
Journal of ovarian research 2015 Dec 2;8:80
Journal of ovarian research 2015 Dec 2;8:80
The Mediator subunit MED23 couples H2B mono-ubiquitination to transcriptional control and cell fate determination.
Yao X, Tang Z, Fu X, Yin J, Liang Y, Li C, Li H, Tian Q, Roeder RG, Wang G
The EMBO journal 2015 Dec 2;34(23):2885-902
The EMBO journal 2015 Dec 2;34(23):2885-902
Involvement of AMPK/SIRT1 pathway in anti-allodynic effect of troxerutin in CCI-induced neuropathic pain.
Gui Y, Li A, Chen F, Zhou H, Tang Y, Chen L, Chen S, Duan S
European journal of pharmacology 2015 Dec 15;769:234-41
European journal of pharmacology 2015 Dec 15;769:234-41
miRNA-204 drives cardiomyocyte proliferation via targeting Jarid2.
Liang D, Li J, Wu Y, Zhen L, Li C, Qi M, Wang L, Deng F, Huang J, Lv F, Liu Y, Ma X, Yu Z, Zhang Y, Chen YH
International journal of cardiology 2015 Dec 15;201:38-48
International journal of cardiology 2015 Dec 15;201:38-48
Genipin inhibits NLRP3 and NLRC4 inflammasome activation via autophagy suppression.
Yu SX, Du CT, Chen W, Lei QQ, Li N, Qi S, Zhang XJ, Hu GQ, Deng XM, Han WY, Yang YJ
Scientific reports 2015 Dec 11;5:17935
Scientific reports 2015 Dec 11;5:17935
Activation of AMPK restricts coxsackievirus B3 replication by inhibiting lipid accumulation.
Xie W, Wang L, Dai Q, Yu H, He X, Xiong J, Sheng H, Zhang D, Xin R, Qi Y, Hu F, Guo S, Zhang K
Journal of molecular and cellular cardiology 2015 Aug;85:155-67
Journal of molecular and cellular cardiology 2015 Aug;85:155-67
CXCR1/2 antagonism with CXCL8/Interleukin-8 analogue CXCL8(3-72)K11R/G31P restricts lung cancer growth by inhibiting tumor cell proliferation and suppressing angiogenesis.
Khan MN, Wang B, Wei J, Zhang Y, Li Q, Luan X, Cheng JW, Gordon JR, Li F, Liu H
Oncotarget 2015 Aug 28;6(25):21315-27
Oncotarget 2015 Aug 28;6(25):21315-27
The Antiviral Effect of Baicalin on Enterovirus 71 In Vitro.
Li X, Liu Y, Wu T, Jin Y, Cheng J, Wan C, Qian W, Xing F, Shi W
Viruses 2015 Aug 19;7(8):4756-71
Viruses 2015 Aug 19;7(8):4756-71
Cdc42-Interacting Protein 4 Represses E-Cadherin Expression by Promoting β-Catenin Translocation to the Nucleus in Murine Renal Tubular Epithelial Cells.
Xu C, Zhou Q, Liu L, Liu P, Pei G, Zeng R, Han M, Xu G
International journal of molecular sciences 2015 Aug 14;16(8):19170-83
International journal of molecular sciences 2015 Aug 14;16(8):19170-83
si-RNA-mediated knockdown of PDLIM5 suppresses gastric cancer cell proliferation in vitro.
Li Y, Gao Y, Xu Y, Sun X, Song X, Ma H, Yang M
Chemical biology & drug design 2015 Apr;85(4):447-53
Chemical biology & drug design 2015 Apr;85(4):447-53
DNA methylation regulates bromodomain-containing protein 2 expression during adipocyte differentiation.
Sun R, Wu Y, Wang Y, Zang K, Wei H, Wang F, Yu M
Molecular and cellular biochemistry 2015 Apr;402(1-2):23-31
Molecular and cellular biochemistry 2015 Apr;402(1-2):23-31
Ppm1b negatively regulates necroptosis through dephosphorylating Rip3.
Chen W, Wu J, Li L, Zhang Z, Ren J, Liang Y, Chen F, Yang C, Zhou Z, Su SS, Zheng X, Zhang Z, Zhong CQ, Wan H, Xiao M, Lin X, Feng XH, Han J
Nature cell biology 2015 Apr;17(4):434-44
Nature cell biology 2015 Apr;17(4):434-44
GSK3β-Dzip1-Rab8 cascade regulates ciliogenesis after mitosis.
Zhang B, Zhang T, Wang G, Wang G, Chi W, Jiang Q, Zhang C
PLoS biology 2015 Apr;13(4):e1002129
PLoS biology 2015 Apr;13(4):e1002129
MicroRNA‑133b inhibits connective tissue growth factor in colorectal cancer and correlates with the clinical stage of the disease.
Guo Y, Li X, Lin C, Zhang Y, Hu G, Zhou J, Du J, Gao K, Gan Y, Deng H
Molecular medicine reports 2015 Apr;11(4):2805-12
Molecular medicine reports 2015 Apr;11(4):2805-12
Modification of BECN1 by ISG15 plays a crucial role in autophagy regulation by type I IFN/interferon.
Xu D, Zhang T, Xiao J, Zhu K, Wei R, Wu Z, Meng H, Li Y, Yuan J
Autophagy 2015 Apr 3;11(4):617-28
Autophagy 2015 Apr 3;11(4):617-28
The tumor suppressor role of miR-124 in osteosarcoma.
Geng S, Zhang X, Chen J, Liu X, Zhang H, Xu X, Ma Y, Li B, Zhang Y, Bi Z, Yang C
PloS one 2014;9(6):e91566
PloS one 2014;9(6):e91566
Megakaryocytic differentiation of K562 cells induced by PMA reduced the activity of respiratory chain complex IV.
Huang R, Zhao L, Chen H, Yin RH, Li CY, Zhan YQ, Zhang JH, Ge CH, Yu M, Yang XM
PloS one 2014;9(5):e96246
PloS one 2014;9(5):e96246
MicroRNA-424 is down-regulated in hepatocellular carcinoma and suppresses cell migration and invasion through c-Myb.
Yu L, Ding GF, He C, Sun L, Jiang Y, Zhu L
PloS one 2014;9(3):e91661
PloS one 2014;9(3):e91661
The self-interaction of a nodavirus replicase is enhanced by mitochondrial membrane lipids.
Qiu Y, Wang Z, Liu Y, Han Y, Miao M, Qi N, Yang J, Xia H, Li X, Qin CF, Hu Y, Zhou X
PloS one 2014;9(2):e89628
PloS one 2014;9(2):e89628
Leptin downregulates aggrecan through the p38-ADAMST pathway in human nucleus pulposus cells.
Li Z, Yu X, Liang J, Wu WK, Yu J, Shen J
PloS one 2014;9(10):e109595
PloS one 2014;9(10):e109595
MicroRNA-217 regulates WASF3 expression and suppresses tumor growth and metastasis in osteosarcoma.
Shen L, Wang P, Yang J, Li X
PloS one 2014;9(10):e109138
PloS one 2014;9(10):e109138
MicroRNA-10a is down-regulated by DNA methylation and functions as a tumor suppressor in gastric cancer cells.
Jia H, Zhang Z, Zou D, Wang B, Yan Y, Luo M, Dong L, Yin H, Gong B, Li Z, Wang F, Song W, Liu C, Ma Y, Zhang J, Zhao H, Li J, Yu J
PloS one 2014;9(1):e88057
PloS one 2014;9(1):e88057
Sox9 regulates hyperexpression of Wnt1 and Fzd1 in human osteosarcoma tissues and cells.
Liu H, Chen Y, Zhou F, Jie L, Pu L, Ju J, Li F, Dai Z, Wang X, Zhou S
International journal of clinical and experimental pathology 2014;7(8):4795-805
International journal of clinical and experimental pathology 2014;7(8):4795-805
Expression of leucine aminopeptidase 3 (LAP3) correlates with prognosis and malignant development of human hepatocellular carcinoma (HCC).
Tian SY, Chen SH, Shao BF, Cai HY, Zhou Y, Zhou YL, Xu AB
International journal of clinical and experimental pathology 2014;7(7):3752-62
International journal of clinical and experimental pathology 2014;7(7):3752-62
SERPINA3 promotes endometrial cancer cells growth by regulating G2/M cell cycle checkpoint and apoptosis.
Yang GD, Yang XM, Lu H, Ren Y, Ma MZ, Zhu LY, Wang JH, Song WW, Zhang WM, Zhang R, Zhang ZG
International journal of clinical and experimental pathology 2014;7(4):1348-58
International journal of clinical and experimental pathology 2014;7(4):1348-58
Gemcitabine resistance in breast cancer cells regulated by PI3K/AKT-mediated cellular proliferation exerts negative feedback via the MEK/MAPK and mTOR pathways.
Yang XL, Lin FJ, Guo YJ, Shao ZM, Ou ZL
OncoTargets and therapy 2014;7:1033-42
OncoTargets and therapy 2014;7:1033-42
Distinct Orai-coupling domains in STIM1 and STIM2 define the Orai-activating site.
Wang X, Wang Y, Zhou Y, Hendron E, Mancarella S, Andrake MD, Rothberg BS, Soboloff J, Gill DL
Nature communications 2014;5:3183
Nature communications 2014;5:3183
Production of transgenic pigs over-expressing the antiviral gene Mx1.
Yan Q, Yang H, Yang D, Zhao B, Ouyang Z, Liu Z, Fan N, Ouyang H, Gu W, Lai L
Cell regeneration (London, England) 2014;3(1):11
Cell regeneration (London, England) 2014;3(1):11
Type 2 diabetes mellitus control and atherosclerosis prevention in a non-obese rat model using duodenal-jejunal bypass.
Chen X, Huang Z, Ran W, Liao G, Zha L, Wang Z
Experimental and therapeutic medicine 2014 Sep;8(3):856-862
Experimental and therapeutic medicine 2014 Sep;8(3):856-862
High density lipoprotein from patients with valvular heart disease uncouples endothelial nitric oxide synthase.
Chang FJ, Yuan HY, Hu XX, Ou ZJ, Fu L, Lin ZB, Wang ZP, Wang SM, Zhou L, Xu YQ, Wang CP, Xu Z, Zhang X, Zhang CX, Ou JS
Journal of molecular and cellular cardiology 2014 Sep;74:209-19
Journal of molecular and cellular cardiology 2014 Sep;74:209-19
Neuroprotective effect of schizandrin A on oxygen and glucose deprivation/reperfusion-induced cell injury in primary culture of rat cortical neurons.
Wang CP, Li GC, Shi YW, Zhang XC, Li JL, Wang ZW, Ding F, Liang XM
Journal of physiology and biochemistry 2014 Sep;70(3):735-47
Journal of physiology and biochemistry 2014 Sep;70(3):735-47
Altered expression of hypoxia-Inducible factor-1α participates in the epileptogenesis in animal models.
Li J, Jiang G, Chen Y, Chen L, Li Z, Wang Z, Wang X
Synapse (New York, N.Y.) 2014 Sep;68(9):402-9
Synapse (New York, N.Y.) 2014 Sep;68(9):402-9
Regulation of silicosis formation by lysophosphatidic acid and its receptors.
Cong C, Mao L, Zhang Y, Zhao Z, Xu X, Zhao J
Experimental lung research 2014 Sep;40(7):317-26
Experimental lung research 2014 Sep;40(7):317-26
MicroRNA-217 functions as a tumour suppressor gene and correlates with cell resistance to cisplatin in lung cancer.
Guo J, Feng Z, Huang Z, Wang H, Lu W
Molecules and cells 2014 Sep;37(9):664-71
Molecules and cells 2014 Sep;37(9):664-71
Regulation of COX-2 expression by miR-146a in lung cancer cells.
Cornett AL, Lutz CS
RNA (New York, N.Y.) 2014 Sep;20(9):1419-30
RNA (New York, N.Y.) 2014 Sep;20(9):1419-30
SILAC-based quantitative proteomic analysis of secretome between activated and reverted hepatic stellate cells.
Zhang H, Wu P, Chen F, Hao Y, Lao Y, Ren L, Sun L, Sun W, Wei H, Chan DW, Jiang Y, He F
Proteomics 2014 Sep;14(17-18):1977-86
Proteomics 2014 Sep;14(17-18):1977-86
Dioscin attenuates hepatic ischemia-reperfusion injury in rats through inhibition of oxidative-nitrative stress, inflammation and apoptosis.
Tao X, Wan X, Xu Y, Xu L, Qi Y, Yin L, Han X, Lin Y, Peng J
Transplantation 2014 Sep 27;98(6):604-11
Transplantation 2014 Sep 27;98(6):604-11
Hypoxia-inducible factor 1α mediates neuroprotection of hypoxic postconditioning against global cerebral ischemia.
Zhu T, Zhan L, Liang D, Hu J, Lu Z, Zhu X, Sun W, Liu L, Xu E
Journal of neuropathology and experimental neurology 2014 Oct;73(10):975-86
Journal of neuropathology and experimental neurology 2014 Oct;73(10):975-86
Nardilysin-dependent proteolysis of cell-associated VTCN1 (B7-H4) marks type 1 diabetes development.
Radichev IA, Maneva-Radicheva LV, Amatya C, Parker C, Ellefson J, Wasserfall C, Atkinson M, Burn P, Savinov AY
Diabetes 2014 Oct;63(10):3470-82
Diabetes 2014 Oct;63(10):3470-82
CKIP-1 suppresses the adipogenesis of mesenchymal stem cells by enhancing HDAC1-associated repression of C/EBPα.
Li D, Zhu H, Liang C, Li W, Xing G, Ma L, Ding L, Zhang Y, He F, Zhang L
Journal of molecular cell biology 2014 Oct;6(5):368-79
Journal of molecular cell biology 2014 Oct;6(5):368-79
Suppression of toll-like receptor 2 expression inhibits the bioactivity of human hepatocellular carcinoma.
Shi W, Su L, Li Q, Sun L, Lv J, Li J, Cheng B
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2014 Oct;35(10):9627-37
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2014 Oct;35(10):9627-37
PP242 synergizes with suberoylanilide hydroxamic acid to inhibit growth of ovarian cancer cells.
Qin Y, Zhao X, Fang Y
International journal of gynecological cancer : official journal of the International Gynecological Cancer Society 2014 Oct;24(8):1373-80
International journal of gynecological cancer : official journal of the International Gynecological Cancer Society 2014 Oct;24(8):1373-80
The involvement of CXCR7 in modulating the progression of papillary thyroid carcinoma.
Liu Z, Yang L, Teng X, Zhang H, Guan H
The Journal of surgical research 2014 Oct;191(2):379-88
The Journal of surgical research 2014 Oct;191(2):379-88
Up-regulation of hexokinase1 in the right ventricle of monocrotaline induced pulmonary hypertension.
Zhang WH, Qiu MH, Wang XJ, Sun K, Zheng Y, Jing ZC
Respiratory research 2014 Oct 8;15:119
Respiratory research 2014 Oct 8;15:119
MicroRNA-188 suppresses G1/S transition by targeting multiple cyclin/CDK complexes.
Wu J, Lv Q, He J, Zhang H, Mei X, Cui K, Huang N, Xie W, Xu N, Zhang Y
Cell communication and signaling : CCS 2014 Oct 11;12:66
Cell communication and signaling : CCS 2014 Oct 11;12:66
Elevated autocrine EDIL3 protects hepatocellular carcinoma from anoikis through RGD-mediated integrin activation.
Feng MX, Ma MZ, Fu Y, Li J, Wang T, Xue F, Zhang JJ, Qin WX, Gu JR, Zhang ZG, Xia Q
Molecular cancer 2014 Oct 1;13:226
Molecular cancer 2014 Oct 1;13:226
Down-regulation of asparagine synthetase induces cell cycle arrest and inhibits cell proliferation of breast cancer.
Yang H, He X, Zheng Y, Feng W, Xia X, Yu X, Lin Z
Chemical biology & drug design 2014 Nov;84(5):578-84
Chemical biology & drug design 2014 Nov;84(5):578-84
Rho/Rock cross-talks with transforming growth factor-β/Smad pathway participates in lung fibroblast-myofibroblast differentiation.
Ji H, Tang H, Lin H, Mao J, Gao L, Liu J, Wu T
Biomedical reports 2014 Nov;2(6):787-792
Biomedical reports 2014 Nov;2(6):787-792
TBC1D9B functions as a GTPase-activating protein for Rab11a in polarized MDCK cells.
Gallo LI, Liao Y, Ruiz WG, Clayton DR, Li M, Liu YJ, Jiang Y, Fukuda M, Apodaca G, Yin XM
Molecular biology of the cell 2014 Nov 15;25(23):3779-97
Molecular biology of the cell 2014 Nov 15;25(23):3779-97
Effects of the total saponins from Rosa laevigata Michx fruit against acetaminophen-induced liver damage in mice via induction of autophagy and suppression of inflammation and apoptosis.
Dong D, Xu L, Han X, Qi Y, Xu Y, Yin L, Liu K, Peng J
Molecules (Basel, Switzerland) 2014 May 30;19(6):7189-206
Molecules (Basel, Switzerland) 2014 May 30;19(6):7189-206
Nasopharyngeal cancer-specific therapy based on fusion peptide-functionalized lipid nanoparticles.
Luo H, Lu L, Yang F, Wang L, Yang X, Luo Q, Zhang Z
ACS nano 2014 May 27;8(5):4334-47
ACS nano 2014 May 27;8(5):4334-47
Effect of nigranoic acid on Ca²⁺ influx and its downstream signal mechanism in NGF-differentiated PC12 cells.
Yuan XX, Yang LP, Yang ZL, Xiao WL, Sun HD, Wu GS, Luo HR
Journal of ethnopharmacology 2014 May 14;153(3):725-31
Journal of ethnopharmacology 2014 May 14;153(3):725-31
Molecular characterization and expression analysis of the autophagic gene beclin 1 from the purse red common carp (Cyprinus carpio) exposed to cadmium.
Gao D, Xu Z, Kuang X, Qiao P, Liu S, Zhang L, He P, Jadwiga WS, Wang Y, Min W
Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 2014 Mar;160:15-22
Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 2014 Mar;160:15-22
miR-21 promotes human nucleus pulposus cell proliferation through PTEN/AKT signaling.
Liu H, Huang X, Liu X, Xiao S, Zhang Y, Xiang T, Shen X, Wang G, Sheng B
International journal of molecular sciences 2014 Mar 5;15(3):4007-18
International journal of molecular sciences 2014 Mar 5;15(3):4007-18
Novel function of the chromosome 7 open reading frame 41 gene to promote leukemic megakaryocyte differentiation by modulating TPA-induced signaling.
Sun X, Lu B, Hu B, Xiao W, Li W, Huang Z
Blood cancer journal 2014 Mar 28;4:e198
Blood cancer journal 2014 Mar 28;4:e198
Molecular analysis of curcumin-induced polarization of murine RAW264.7 macrophages.
Chen F, Guo N, Cao G, Zhou J, Yuan Z
Journal of cardiovascular pharmacology 2014 Jun;63(6):544-52
Journal of cardiovascular pharmacology 2014 Jun;63(6):544-52
The roles of p38 MAPK/MSK1 signaling pathway in the neuroprotection of hypoxic postconditioning against transient global cerebral ischemia in adult rats.
Zhu P, Zhan L, Zhu T, Liang D, Hu J, Sun W, Hou Q, Zhou H, Wu B, Wang Y, Xu E
Molecular neurobiology 2014 Jun;49(3):1338-49
Molecular neurobiology 2014 Jun;49(3):1338-49
MGARP regulates mouse neocortical development via mitochondrial positioning.
Jia L, Liang T, Yu X, Ma C, Zhang S
Molecular neurobiology 2014 Jun;49(3):1293-308
Molecular neurobiology 2014 Jun;49(3):1293-308
HepaCAM inhibits clear cell renal carcinoma 786-0 cell proliferation via blocking PKCε translocation from cytoplasm to plasma membrane.
Tan B, Tan J, Du H, Quan Z, Xu X, Jiang X, Luo C, Wu X
Molecular and cellular biochemistry 2014 Jun;391(1-2):95-102
Molecular and cellular biochemistry 2014 Jun;391(1-2):95-102
p16 Methylation is associated with chemosensitivity to fluorouracil in patients with advanced gastric cancer.
Wang M, Li Y, Gao J, Li Y, Zhou J, Gu L, Shen L, Deng D
Medical oncology (Northwood, London, England) 2014 Jun;31(6):988
Medical oncology (Northwood, London, England) 2014 Jun;31(6):988
Negative association of R-Ras activation and breast cancer development.
Song J, Zheng B, Bu X, Fei Y, Shi S
Oncology reports 2014 Jun;31(6):2776-84
Oncology reports 2014 Jun;31(6):2776-84
Toxoplasma gondii inhibits apoptosis via a novel STAT3-miR-17-92-Bim pathway in macrophages.
Cai Y, Chen H, Mo X, Tang Y, Xu X, Zhang A, Lun Z, Lu F, Wang Y, Shen J
Cellular signalling 2014 Jun;26(6):1204-12
Cellular signalling 2014 Jun;26(6):1204-12
Activation of JNK1/2 and p38 MAPK signaling pathways promotes enterovirus 71 infection in immature dendritic cells.
Peng H, Shi M, Zhang L, Li Y, Sun J, Zhang L, Wang X, Xu X, Zhang X, Mao Y, Ji Y, Jiang J, Shi W
BMC microbiology 2014 Jun 7;14:147
BMC microbiology 2014 Jun 7;14:147
Oxidored-nitro domain containing protein 1 (NOR1) expression suppresses slug/vimentin but not snail in nasopharyngeal carcinoma: Inhibition of EMT in vitro and in vivo in mice.
Wang W, Li X, Zhang W, Li W, Yi M, Yang J, Zeng Z, Colvin Wanshura LE, McCarthy JB, Fan S, Zheng P, Chen S, Xiang B, Li G
Cancer letters 2014 Jun 28;348(1-2):109-18
Cancer letters 2014 Jun 28;348(1-2):109-18
KIF2A silencing inhibits the proliferation and migration of breast cancer cells and correlates with unfavorable prognosis in breast cancer.
Wang J, Ma S, Ma R, Qu X, Liu W, Lv C, Zhao S, Gong Y
BMC cancer 2014 Jun 21;14:461
BMC cancer 2014 Jun 21;14:461
Mulberroside A protects against ischemic impairment in primary culture of rat cortical neurons after oxygen-glucose deprivation followed by reperfusion.
Wang CP, Zhang LZ, Li GC, Shi YW, Li JL, Zhang XC, Wang ZW, Ding F, Liang XM
Journal of neuroscience research 2014 Jul;92(7):944-54
Journal of neuroscience research 2014 Jul;92(7):944-54
LPS induced miR-181a promotes pancreatic cancer cell migration via targeting PTEN and MAP2K4.
Liu J, Xu D, Wang Q, Zheng D, Jiang X, Xu L
Digestive diseases and sciences 2014 Jul;59(7):1452-60
Digestive diseases and sciences 2014 Jul;59(7):1452-60
Regulated intramembrane proteolysis of the frontotemporal lobar degeneration risk factor, TMEM106B, by signal peptide peptidase-like 2a (SPPL2a).
Brady OA, Zhou X, Hu F
The Journal of biological chemistry 2014 Jul 11;289(28):19670-80
The Journal of biological chemistry 2014 Jul 11;289(28):19670-80
The inhibitory effect of IFN-γ on protease HTRA1 expression in rheumatoid arthritis.
Hou Y, Lin H, Zhu L, Liu Z, Hu F, Shi J, Yang T, Shi X, Guo H, Tan X, Zhang L, Wang Q, Li Z, Zhao Y
Journal of immunology (Baltimore, Md. : 1950) 2014 Jul 1;193(1):130-8
Journal of immunology (Baltimore, Md. : 1950) 2014 Jul 1;193(1):130-8
Neuroprotection by (-)-epigallocatechin-3-gallate in a rat model of stroke is mediated through inhibition of endoplasmic reticulum stress.
Yao C, Zhang J, Liu G, Chen F, Lin Y
Molecular medicine reports 2014 Jan;9(1):69-76
Molecular medicine reports 2014 Jan;9(1):69-76
Microgravity inhibition of lipopolysaccharide-induced tumor necrosis factor-α expression in macrophage cells.
Wang C, Luo H, Zhu L, Yang F, Chu Z, Tian H, Feng M, Zhao Y, Shang P
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2014 Jan;63(1):91-8
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2014 Jan;63(1):91-8
iTRAQ-based proteomic analysis of dioscin on human HCT-116 colon cancer cells.
Chen H, Xu L, Yin L, Xu Y, Han X, Qi Y, Zhao Y, Liu K, Peng J
Proteomics 2014 Jan;14(1):51-73
Proteomics 2014 Jan;14(1):51-73
Dengue virus subgenomic RNA induces apoptosis through the Bcl-2-mediated PI3k/Akt signaling pathway.
Liu Y, Liu H, Zou J, Zhang B, Yuan Z
Virology 2014 Jan 5;448:15-25
Virology 2014 Jan 5;448:15-25
Long non-coding RNA UCA1 promotes breast tumor growth by suppression of p27 (Kip1).
Huang J, Zhou N, Watabe K, Lu Z, Wu F, Xu M, Mo YY
Cell death & disease 2014 Jan 23;5:e1008
Cell death & disease 2014 Jan 23;5:e1008
High glucose induces activation of the local renin‑angiotensin system in glomerular endothelial cells.
Peng H, Xing YF, Ye ZC, Li CM, Luo PL, Li M, Lou TQ
Molecular medicine reports 2014 Feb;9(2):450-6
Molecular medicine reports 2014 Feb;9(2):450-6
Pretreatment of mice with oligonucleotide prop5 protects them from influenza virus infections.
Li K, Zhou Z, Wang YO, Liu J, Zhao HB, Yang J, Wang SQ
Viruses 2014 Feb 6;6(2):573-81
Viruses 2014 Feb 6;6(2):573-81
Akt/Ezrin Tyr353/NF-κB pathway regulates EGF-induced EMT and metastasis in tongue squamous cell carcinoma.
Wang Y, Lin Z, Sun L, Fan S, Huang Z, Zhang D, Yang Z, Li J, Chen W
British journal of cancer 2014 Feb 4;110(3):695-705
British journal of cancer 2014 Feb 4;110(3):695-705
A microtubule-associated zinc finger protein, BuGZ, regulates mitotic chromosome alignment by ensuring Bub3 stability and kinetochore targeting.
Jiang H, He X, Wang S, Jia J, Wan Y, Wang Y, Zeng R, Yates J 3rd, Zhu X, Zheng Y
Developmental cell 2014 Feb 10;28(3):268-81
Developmental cell 2014 Feb 10;28(3):268-81
An alternative splicing isoform of MITA antagonizes MITA-mediated induction of type I IFNs.
Chen H, Pei R, Zhu W, Zeng R, Wang Y, Wang Y, Lu M, Chen X
Journal of immunology (Baltimore, Md. : 1950) 2014 Feb 1;192(3):1162-70
Journal of immunology (Baltimore, Md. : 1950) 2014 Feb 1;192(3):1162-70
Protein profiling the differences between diabetic and normal mouse cumulus cells.
Jiang GJ, Ma JY, Zhang GL, Mo FF, Zhang DW, Gao SH, Li XL
Molecular reproduction and development 2014 Dec;81(12):1080-5
Molecular reproduction and development 2014 Dec;81(12):1080-5
Levofloxacin increases the effect of serum deprivation on anoikis of rat nucleus pulposus cells via Bax/Bcl-2/caspase-3 pathway.
Yang SD, Bai ZL, Zhang F, Ma L, Yang DL, Ding WY
Toxicology mechanisms and methods 2014 Dec;24(9):688-96
Toxicology mechanisms and methods 2014 Dec;24(9):688-96
Differential effects of agonistic 4-1BB (CD137) monoclonal antibody on the maturation and functions of hypoxic dendritic cells.
Shang Q, Dong Z, Liu C, Bai Y, Guo C, Zhang L, Wang Q
International immunopharmacology 2014 Dec;23(2):609-16
International immunopharmacology 2014 Dec;23(2):609-16
Effects of sodium fluoride treatment in vitro on cell proliferation, BMP-2 and BMP-3 expression in human osteosarcoma MG-63 cells.
Wei Y, Wu Y, Zeng B, Zhang H
Biological trace element research 2014 Dec;162(1-3):18-25
Biological trace element research 2014 Dec;162(1-3):18-25
A recessive variant of XRCC4 predisposes to non- BRCA1/2 breast cancer in chinese women and impairs the DNA damage response via dysregulated nuclear localization.
He M, Hu X, Chen L, Cao AY, Yu KD, Shi TY, Kuang XY, Shi WB, Ling H, Li S, Qiao F, Yao L, Wei Q, Di GH, Shao ZM
Oncotarget 2014 Dec 15;5(23):12218-32
Oncotarget 2014 Dec 15;5(23):12218-32
Calreticulin promotes migration and invasion of esophageal cancer cells by upregulating neuropilin-1 expression via STAT5A.
Shi F, Shang L, Pan BQ, Wang XM, Jiang YY, Hao JJ, Zhang Y, Cai Y, Xu X, Zhan QM, Wang MR
Clinical cancer research : an official journal of the American Association for Cancer Research 2014 Dec 1;20(23):6153-62
Clinical cancer research : an official journal of the American Association for Cancer Research 2014 Dec 1;20(23):6153-62
Decreased expression of TRIM3 is associated with poor prognosis in patients with primary hepatocellular carcinoma.
Chao J, Zhang XF, Pan QZ, Zhao JJ, Jiang SS, Wang Y, Zhang JH, Xia JC
Medical oncology (Northwood, London, England) 2014 Aug;31(8):102
Medical oncology (Northwood, London, England) 2014 Aug;31(8):102
Potent effects of flavonoid-rich extract from Rosa laevigata Michx fruit against hydrogen peroxide-induced damage in PC12 cells via attenuation of oxidative stress, inflammation and apoptosis.
Liu M, Xu Y, Han X, Liang C, Yin L, Xu L, Qi Y, Zhao Y, Peng J, Sun C
Molecules (Basel, Switzerland) 2014 Aug 7;19(8):11816-32
Molecules (Basel, Switzerland) 2014 Aug 7;19(8):11816-32
microRNA 490-3P enhances the drug-resistance of human ovarian cancer cells.
Chen S, Chen X, Xiu YL, Sun KX, Zong ZH, Zhao Y
Journal of ovarian research 2014 Aug 31;7:84
Journal of ovarian research 2014 Aug 31;7:84
DNA methylation-mediated silencing of matricellular protein dermatopontin promotes hepatocellular carcinoma metastasis by α3β1 integrin-Rho GTPase signaling.
Fu Y, Feng MX, Yu J, Ma MZ, Liu XJ, Li J, Yang XM, Wang YH, Zhang YL, Ao JP, Xue F, Qin W, Gu J, Xia Q, Zhang ZG
Oncotarget 2014 Aug 30;5(16):6701-15
Oncotarget 2014 Aug 30;5(16):6701-15
Oxidoreductase activity is necessary for N-glycosylation of cysteine-proximal acceptor sites in glycoproteins.
Cherepanova NA, Shrimal S, Gilmore R
The Journal of cell biology 2014 Aug 18;206(4):525-39
The Journal of cell biology 2014 Aug 18;206(4):525-39
Puerarin protected the brain from cerebral ischemia injury via astrocyte apoptosis inhibition.
Wang N, Zhang Y, Wu L, Wang Y, Cao Y, He L, Li X, Zhao J
Neuropharmacology 2014 Apr;79:282-9
Neuropharmacology 2014 Apr;79:282-9
The role of SIRT6 in the differentiation of vascular smooth muscle cells in response to cyclic strain.
Yao QP, Zhang P, Qi YX, Chen SG, Shen BR, Han Y, Yan ZQ, Jiang ZL
The international journal of biochemistry & cell biology 2014 Apr;49:98-104
The international journal of biochemistry & cell biology 2014 Apr;49:98-104
A synergic role of caspase-6 and caspase-3 in Tau truncation at D421 induced by H2O 2.
Zhao H, Zhao W, Lok K, Wang Z, Yin M
Cellular and molecular neurobiology 2014 Apr;34(3):369-78
Cellular and molecular neurobiology 2014 Apr;34(3):369-78
Protective effects of the total saponins from Dioscorea nipponica Makino against carbon tetrachloride-induced liver injury in mice through suppression of apoptosis and inflammation.
Yu H, Zheng L, Yin L, Xu L, Qi Y, Han X, Xu Y, Liu K, Peng J
International immunopharmacology 2014 Apr;19(2):233-44
International immunopharmacology 2014 Apr;19(2):233-44
Sine oculis homeobox homolog 1 promotes α5β1-mediated invasive migration and metastasis of cervical cancer cells.
Liu D, Zhang XX, Wan DY, Xi BX, Ma D, Wang H, Gao QL
Biochemical and biophysical research communications 2014 Apr 4;446(2):549-54
Biochemical and biophysical research communications 2014 Apr 4;446(2):549-54
Umbilical cord blood cells regulate the differentiation of endogenous neural stem cells in hypoxic ischemic neonatal rats via the hedgehog signaling pathway.
Wang X, Zhao Y, Wang X
Brain research 2014 Apr 29;1560:18-26
Brain research 2014 Apr 29;1560:18-26
IKKα restoration via EZH2 suppression induces nasopharyngeal carcinoma differentiation.
Yan M, Zhang Y, He B, Xiang J, Wang ZF, Zheng FM, Xu J, Chen MY, Zhu YL, Wen HJ, Wan XB, Yue CF, Yang N, Zhang W, Zhang JL, Wang J, Wang Y, Li LH, Zeng YX, Lam EW, Hung MC, Liu Q
Nature communications 2014 Apr 17;5:3661
Nature communications 2014 Apr 17;5:3661
Cadmium induces liver cell apoptosis through caspase-3A activation in purse red common carp (Cyprinus carpio).
Gao D, Xu Z, Qiao P, Liu S, Zhang L, He P, Zhang X, Wang Y, Min W
PloS one 2013;8(12):e83423
PloS one 2013;8(12):e83423
MicroRNA-10b promotes nucleus pulposus cell proliferation through RhoC-Akt pathway by targeting HOXD10 in intervetebral disc degeneration.
Yu X, Li Z, Shen J, Wu WK, Liang J, Weng X, Qiu G
PloS one 2013;8(12):e83080
PloS one 2013;8(12):e83080
Simvastatin alleviates hyperpermeability of glomerular endothelial cells in early-stage diabetic nephropathy by inhibition of RhoA/ROCK1.
Peng H, Luo P, Li Y, Wang C, Liu X, Ye Z, Li C, Lou T
PloS one 2013;8(11):e80009
PloS one 2013;8(11):e80009
Identification of three antiviral inhibitors against Japanese encephalitis virus from library of pharmacologically active compounds 1280.
Fang J, Sun L, Peng G, Xu J, Zhou R, Cao S, Chen H, Song Y
PloS one 2013;8(11):e78425
PloS one 2013;8(11):e78425
Resolvin D1 reverts lipopolysaccharide-induced TJ proteins disruption and the increase of cellular permeability by regulating IκBα signaling in human vascular endothelial cells.
Zhang X, Wang T, Gui P, Yao C, Sun W, Wang L, Wang H, Xie W, Yao S, Lin Y, Wu Q
Oxidative medicine and cellular longevity 2013;2013:185715
Oxidative medicine and cellular longevity 2013;2013:185715
Anti-miRNA-23a oligonucleotide suppresses glioma cells growth by targeting apoptotic protease activating factor-1.
Lian S, Shi R, Bai T, Liu Y, Miao W, Wang H, Liu X, Fan Y
Current pharmaceutical design 2013;19(35):6382-9
Current pharmaceutical design 2013;19(35):6382-9
Proteomic studies of multiple myeloma in RPMI8226 cell line treated with bendamustine.
Sun C, Li J, Gu J, Liu J, Huang B
Journal of B.U.ON. : official journal of the Balkan Union of Oncology 2013 Oct-Dec;18(4):996-1005
Journal of B.U.ON. : official journal of the Balkan Union of Oncology 2013 Oct-Dec;18(4):996-1005
Differential roles of C-terminal Eps15 homology domain proteins as vesiculators and tubulators of recycling endosomes.
Cai B, Giridharan SSP, Zhang J, Saxena S, Bahl K, Schmidt JA, Sorgen PL, Guo W, Naslavsky N, Caplan S
The Journal of biological chemistry 2013 Oct 18;288(42):30172-30180
The Journal of biological chemistry 2013 Oct 18;288(42):30172-30180
Molecular cloning, immunohistochemical localization, characterization and expression analysis of caspase-9 from the purse red common carp (Cyprinus carpio) exposed to cadmium.
Gao D, Xu Z, Zhang X, Wang H, Wang Y, Min W
Aquatic toxicology (Amsterdam, Netherlands) 2013 Oct 15;142-143:53-62
Aquatic toxicology (Amsterdam, Netherlands) 2013 Oct 15;142-143:53-62
Lipopolysaccharide increases the incidence of collagen-induced arthritis in mice through induction of protease HTRA-1 expression.
Hou Y, Lin H, Zhu L, Liu Z, Hu F, Shi J, Yang T, Shi X, Zhu M, Godley BF, Wang Q, Li Z, Zhao Y
Arthritis and rheumatism 2013 Nov;65(11):2835-46
Arthritis and rheumatism 2013 Nov;65(11):2835-46
Effects of perchlorate on BDE-47-induced alteration thyroid hormone and gene expression of in the hypothalamus-pituitary-thyroid axis in zebrafish larvae.
Zhao X, Wang S, Li D, You H, Ren X
Environmental toxicology and pharmacology 2013 Nov;36(3):1176-85
Environmental toxicology and pharmacology 2013 Nov;36(3):1176-85
MicroRNA-124 mediates the cholinergic anti-inflammatory action through inhibiting the production of pro-inflammatory cytokines.
Sun Y, Li Q, Gui H, Xu DP, Yang YL, Su DF, Liu X
Cell research 2013 Nov;23(11):1270-83
Cell research 2013 Nov;23(11):1270-83
Synergistic anti-glioma effect of Hydroxygenkwanin and Apigenin in vitro.
Wang Y, Xu YS, Yin LH, Xu LN, Peng JY, Zhou H, Kang W
Chemico-biological interactions 2013 Nov 25;206(2):346-55
Chemico-biological interactions 2013 Nov 25;206(2):346-55
Amyloid-β(1-42) oligomer accelerates senescence in adult hippocampal neural stem/progenitor cells via formylpeptide receptor 2.
He N, Jin WL, Lok KH, Wang Y, Yin M, Wang ZJ
Cell death & disease 2013 Nov 21;4:e924
Cell death & disease 2013 Nov 21;4:e924
Fructose-1,6-bisphosphatase, Malate Dehydrogenase, Isocitrate Lyase, Phosphoenolpyruvate Carboxykinase, Glyceraldehyde-3-phosphate Dehydrogenase, and Cyclophilin A are secreted in Saccharomyces cerevisiae grown in low glucose.
Giardina BJ, Chiang HL
Communicative & integrative biology 2013 Nov 1;6(6):e27216
Communicative & integrative biology 2013 Nov 1;6(6):e27216
Protection of the flavonoid fraction from Rosa laevigata Michx fruit against carbon tetrachloride-induced acute liver injury in mice.
Zhang S, Lu B, Han X, Xu L, Qi Y, Yin L, Xu Y, Zhao Y, Liu K, Peng J
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2013 May;55:60-9
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2013 May;55:60-9
PPE38 of Mycobacterium marinum triggers the cross-talk of multiple pathways involved in the host response, as revealed by subcellular quantitative proteomics.
Wang H, Dong D, Tang S, Chen X, Gao Q
Journal of proteome research 2013 May 3;12(5):2055-66
Journal of proteome research 2013 May 3;12(5):2055-66
Inositol-requiring protein 1α signaling pathway is activated in the temporal cortex of patients with mesial temporal lobe epilepsy.
Liu GL, Wang KY, Guo H, Zhao SJ, Shen Y, Zhao YB
Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology 2013 Mar;34(3):357-64
Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology 2013 Mar;34(3):357-64
Salidroside protects against hydrogen peroxide-induced injury in HUVECs via the regulation of REDD1 and mTOR activation.
Xu MC, Shi HM, Wang H, Gao XF
Molecular medicine reports 2013 Jul;8(1):147-53
Molecular medicine reports 2013 Jul;8(1):147-53
c-Src regulates cell cycle proteins expression through protein kinase B/glycogen synthase kinase 3 beta and extracellular signal-regulated kinases 1/2 pathways in MCF-7 cells.
Liu X, Du L, Feng R
Acta biochimica et biophysica Sinica 2013 Jul;45(7):586-92
Acta biochimica et biophysica Sinica 2013 Jul;45(7):586-92
Identification of STAT2 serine 287 as a novel regulatory phosphorylation site in type I interferon-induced cellular responses.
Steen HC, Nogusa S, Thapa RJ, Basagoudanavar SH, Gill AL, Merali S, Barrero CA, Balachandran S, Gamero AM
The Journal of biological chemistry 2013 Jan 4;288(1):747-58
The Journal of biological chemistry 2013 Jan 4;288(1):747-58
INMAP, a novel truncated version of POLR3B, represses AP-1 and p53 transcriptional activity.
Yunlei Z, Zhe C, Yan L, Pengcheng W, Yanbo Z, Le S, Qianjin L
Molecular and cellular biochemistry 2013 Feb;374(1-2):81-9
Molecular and cellular biochemistry 2013 Feb;374(1-2):81-9
Hyperforin attenuates brain damage induced by transient middle cerebral artery occlusion (MCAO) in rats via inhibition of TRPC6 channels degradation.
Lin Y, Zhang JC, Fu J, Chen F, Wang J, Wu ZL, Yuan SY
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2013 Feb;33(2):253-62
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2013 Feb;33(2):253-62
PES1 regulates sensitivity of colorectal cancer cells to anticancer drugs.
Xie W, Qu L, Meng L, Liu C, Wu J, Shou C
Biochemical and biophysical research communications 2013 Feb 15;431(3):460-5
Biochemical and biophysical research communications 2013 Feb 15;431(3):460-5
Neuroprotective effect of calcitriol on ischemic/reperfusion injury through the NR3A/CREB pathways in the rat hippocampus.
Fu J, Xue R, Gu J, Xiao Y, Zhong H, Pan X, Ran R
Molecular medicine reports 2013 Dec;8(6):1708-14
Molecular medicine reports 2013 Dec;8(6):1708-14
Isoquercetin protects cortical neurons from oxygen-glucose deprivation-reperfusion induced injury via suppression of TLR4-NF-кB signal pathway.
Wang CP, Li JL, Zhang LZ, Zhang XC, Yu S, Liang XM, Ding F, Wang ZW
Neurochemistry international 2013 Dec;63(8):741-9
Neurochemistry international 2013 Dec;63(8):741-9
Cadmium triggers kidney cell apoptosis of purse red common carp (Cyprinus carpio) without caspase-8 activation.
Gao D, Xu Z, Zhang X, Zhu C, Wang Y, Min W
Developmental and comparative immunology 2013 Dec;41(4):728-37
Developmental and comparative immunology 2013 Dec;41(4):728-37
STAT3-dependent transactivation of miRNA genes following Toxoplasma gondii infection in macrophage.
Cai Y, Chen H, Jin L, You Y, Shen J
Parasites & vectors 2013 Dec 16;6:356
Parasites & vectors 2013 Dec 16;6:356
miR-133b, a muscle-specific microRNA, is a novel prognostic marker that participates in the progression of human colorectal cancer via regulation of CXCR4 expression.
Duan FT, Qian F, Fang K, Lin KY, Wang WT, Chen YQ
Molecular cancer 2013 Dec 13;12:164
Molecular cancer 2013 Dec 13;12:164
Effects of flavonoids from Rosa laevigata Michx fruit against high-fat diet-induced non-alcoholic fatty liver disease in rats.
Zhang S, Zheng L, Dong D, Xu L, Yin L, Qi Y, Han X, Lin Y, Liu K, Peng J
Food chemistry 2013 Dec 1;141(3):2108-16
Food chemistry 2013 Dec 1;141(3):2108-16
Neuroprotectin D1 attenuates brain damage induced by transient middle cerebral artery occlusion in rats through TRPC6/CREB pathways.
Yao C, Zhang J, Chen F, Lin Y
Molecular medicine reports 2013 Aug;8(2):543-50
Molecular medicine reports 2013 Aug;8(2):543-50
Induction of apoptosis in infantile hemangioma endothelial cells by propranolol.
Tu JB, Ma RZ, Dong Q, Jiang F, Hu XY, Li QY, Pattar P, Zhang H
Experimental and therapeutic medicine 2013 Aug;6(2):574-578
Experimental and therapeutic medicine 2013 Aug;6(2):574-578
Lumbrokinase attenuates diabetic nephropathy through regulating extracellular matrix degradation in Streptozotocin-induced diabetic rats.
Sun H, Ge N, Shao M, Cheng X, Li Y, Li S, Shen J
Diabetes research and clinical practice 2013 Apr;100(1):85-95
Diabetes research and clinical practice 2013 Apr;100(1):85-95
Vps34p is required for the decline of extracellular fructose-1,6-bisphosphatase in the vacuole import and degradation pathway.
Alibhoy AA, Giardina BJ, Dunton DD, Chiang HL
The Journal of biological chemistry 2012 Sep 21;287(39):33080-93
The Journal of biological chemistry 2012 Sep 21;287(39):33080-93
The p16-specific reactivation and inhibition of cell migration through demethylation of CpG islands by engineered transcription factors.
Zhang B, Xiang S, Zhong Q, Yin Y, Gu L, Deng D
Human gene therapy 2012 Oct;23(10):1071-81
Human gene therapy 2012 Oct;23(10):1071-81
Phosphatase of regenerating liver-3 directly interacts with integrin β1 and regulates its phosphorylation at tyrosine 783.
Tian W, Qu L, Meng L, Liu C, Wu J, Shou C
BMC biochemistry 2012 Oct 23;13:22
BMC biochemistry 2012 Oct 23;13:22
miR-129-3p controls cilia assembly by regulating CP110 and actin dynamics.
Cao J, Shen Y, Zhu L, Xu Y, Zhou Y, Wu Z, Li Y, Yan X, Zhu X
Nature cell biology 2012 Jun 10;14(7):697-706
Nature cell biology 2012 Jun 10;14(7):697-706
Embryonic liver fodrin involved in hepatic stellate cell activation and formation of regenerative nodule in liver cirrhosis.
Wang Z, Liu F, Tu W, Chang Y, Yao J, Wu W, Jiang X, He X, Lin J, Song Y
Journal of cellular and molecular medicine 2012 Jan;16(1):118-28
Journal of cellular and molecular medicine 2012 Jan;16(1):118-28
A novel mouse model of gastric cancer with human gastric microenvironment.
Zheng MJ, Wang J, Chen YW, Xu L, Xue DD, Fu W, Zhang YF, Du Q, Zhao Y, Ling LJ, Ding Q, Liu XA, Zha XM, Zheng W, Xia TS, Wang S
Cancer letters 2012 Dec 1;325(1):108-15
Cancer letters 2012 Dec 1;325(1):108-15
β-2 spectrin is involved in hepatocyte proliferation through the interaction of TGFβ/Smad and PI3K/AKT signalling.
Wang Z, Song Y, Tu W, He X, Lin J, Liu F
Liver international : official journal of the International Association for the Study of the Liver 2012 Aug;32(7):1103-11
Liver international : official journal of the International Association for the Study of the Liver 2012 Aug;32(7):1103-11
Genetic and epigenetic control of UNC5C expression in human renal cell carcinoma.
Lv D, Zhao W, Dong D, Qian XP, Zhang Y, Tian XJ, Zhang J
European journal of cancer (Oxford, England : 1990) 2011 Sep;47(13):2068-76
European journal of cancer (Oxford, England : 1990) 2011 Sep;47(13):2068-76
SCFFBXL¹⁵ regulates BMP signalling by directing the degradation of HECT-type ubiquitin ligase Smurf1.
Cui Y, He S, Xing C, Lu K, Wang J, Xing G, Meng A, Jia S, He F, Zhang L
The EMBO journal 2011 May 13;30(13):2675-89
The EMBO journal 2011 May 13;30(13):2675-89
Transplanted olfactory ensheathing cells reduce the gliotic injury response of Müller cells in a rat model of retinitis pigmentosa.
Huo SJ, Li Y, Raisman G, Yin ZQ
Brain research 2011 Mar 25;1382:238-44
Brain research 2011 Mar 25;1382:238-44
Differentiation of human bone marrow mesenchymal stem cells into neuron-like cells in vitro.
Zeng R, Wang LW, Hu ZB, Guo WT, Wei JS, Lin H, Sun X, Chen LX, Yang LJ
Spine 2011 Jun;36(13):997-1005
Spine 2011 Jun;36(13):997-1005
Fabp3 inhibits proliferation and promotes apoptosis of embryonic myocardial cells.
Zhu C, Hu DL, Liu YQ, Zhang QJ, Chen FK, Kong XQ, Cao KJ, Zhang JS, Qian LM
Cell biochemistry and biophysics 2011 Jul;60(3):259-66
Cell biochemistry and biophysics 2011 Jul;60(3):259-66
Differential expression of microRNAs in cardiac myocytes compared to undifferentiated P19 cells.
Hu DL, Liu YQ, Chen FK, Sheng YH, Yang R, Kong XQ, Cao KJ, Zhang JS, Qian LM
International journal of molecular medicine 2011 Jul;28(1):59-64
International journal of molecular medicine 2011 Jul;28(1):59-64
Involvement of IRE1α signaling in the hippocampus in patients with mesial temporal lobe epilepsy.
Liu G, Guo H, Guo C, Zhao S, Gong D, Zhao Y
Brain research bulletin 2011 Jan 15;84(1):94-102
Brain research bulletin 2011 Jan 15;84(1):94-102
Differential proteome analysis of bone marrow mesenchymal stem cells from adolescent idiopathic scoliosis patients.
Zhuang Q, Li J, Wu Z, Zhang J, Sun W, Li T, Yan Y, Jiang Y, Zhao RC, Qiu G
PloS one 2011 Apr 22;6(4):e18834
PloS one 2011 Apr 22;6(4):e18834
Functional characterization of inward rectifier potassium ion channel in murine fetal ventricular cardiomyocytes.
Liu A, Tang M, Xi J, Gao L, Zheng Y, Luo H, Hu X, Zhao F, Reppel M, Hescheler J, Liang H
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2010;26(3):413-20
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2010;26(3):413-20
Alpha1,3 fucosyltransferase VII plays a role in colorectal carcinoma metastases by promoting the carbohydration of glycoprotein CD24.
Li W, Zhang W, Luo J, Cao A, Zhang Y, Huang D, Sheng W, Cai S, Li J
Oncology reports 2010 Jun;23(6):1609-17
Oncology reports 2010 Jun;23(6):1609-17
Inhibition of epithelial to mesenchymal transition in metastatic breast carcinoma cells by c-Src suppression.
Liu X, Feng R
Acta biochimica et biophysica Sinica 2010 Jul;42(7):496-501
Acta biochimica et biophysica Sinica 2010 Jul;42(7):496-501
The role of enoyl-CoA hydratase short chain 1 and peroxiredoxin 3 in PP2-induced apoptosis in human breast cancer MCF-7 cells.
Liu X, Feng R, Du L
FEBS letters 2010 Jul 16;584(14):3185-92
FEBS letters 2010 Jul 16;584(14):3185-92
SZ-685C, a marine anthraquinone, is a potent inducer of apoptosis with anticancer activity by suppression of the Akt/FOXO pathway.
Xie G, Zhu X, Li Q, Gu M, He Z, Wu J, Li J, Lin Y, Li M, She Z, Yuan J
British journal of pharmacology 2010 Feb 1;159(3):689-97
British journal of pharmacology 2010 Feb 1;159(3):689-97
Epidermal growth factor stimulates human trophoblast cell migration through Rho A and Rho C activation.
Han J, Li L, Hu J, Yu L, Zheng Y, Guo J, Zheng X, Yi P, Zhou Y
Endocrinology 2010 Apr;151(4):1732-42
Endocrinology 2010 Apr;151(4):1732-42
Electrophysiological study on differentiation of rat bone marrow stromal stem cells into neuron-like cells in vitro by edaravone.
Zeng R, Hu ZB, Guo WT, Lin H, Sun X, Wei JS, Wu SK
Chinese journal of traumatology = Zhonghua chuang shang za zhi 2009 Jun;12(3):167-72
Chinese journal of traumatology = Zhonghua chuang shang za zhi 2009 Jun;12(3):167-72
Palladin is overexpressed in the non-neoplastic stroma of infiltrating ductal adenocarcinomas of the pancreas, but is only rarely overexpressed in neoplastic cells.
Salaria SN, Illei P, Sharma R, Walter KM, Klein AP, Eshleman JR, Maitra A, Schulick R, Winter J, Ouellette MM, Goggins M, Hruban R
Cancer biology & therapy 2007 Mar;6(3):324-8
Cancer biology & therapy 2007 Mar;6(3):324-8
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Western blot of Hela cell with anti-GAPDH (60004-1-Ig) at various dilutions.
- Sample type
- cell line
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The GAPDH antibody from Proteintech is a mouse monoclonal antibody to a recombinant protein of human GAPDH. This antibody recognizes human,mouse,rat antigen. The GAPDH antibody has been validated for the following applications: ELISA, IHC, WB, IP, IF analysis.
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunofluorescent analysis of Ethacrynic acid treated HeLa cells using 60004-1-Ig( GAPDH Antibody) at dilution of 1:50 and N/A
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- IP result of anti-GAPDH (60004-1-Ig for IP and Detection) with HeLa cell lysate.
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human breast cancer using 60004-1-Ig(GAPDH antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human breast cancer using 60004-1-Ig(GAPDH antibody) at dilution of 1:50 (under 40x lens)
- Sample type
- tissue
