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- Antibody Data
- Antigen structure
- References [10595]
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- Western blot [2]
- Immunocytochemistry [1]
- Immunoprecipitation [1]
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- Product number
- 60004-1-Ig - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#60004-1-Ig, RRID:AB_2107436
- Product name
- GAPDH antibody
- Antibody type
- Monoclonal
- Description
- GAPDH antibody (Cat. #60004-1-Ig) is a mouse monoclonal antibody that shows reactivity with human, mouse, rat, yeast, plant, zebrafish and has been validated for the following applications: FC, IF, IP, WB, ELISA.
- Reactivity
- Human, Mouse, Rat, Yeast, Zebrafish
- Host
- Mouse
- Conjugate
- Unconjugated
- Isotype
- IgG
- Antibody clone number
- 1E6D9
- Vial size
- 150ul
Submitted references Hydroxycitric Acid Tripotassium Hydrate Attenuates Monocrotaline and Hypoxia-Induced Pulmonary Hypertension in Rats.
In vitro and in vivo studies on the effect of a mitochondrial fusion promoter on Leydig cell integrity and function.
Deactivation of the Unfolded Protein Response Aggravated Renal AA Amyloidosis in HSF1 Deficiency Mice.
GPX4 inhibits apoptosis of thyroid cancer cells through regulating the FKBP8/Bcl-2 axis.
Proximity Mapping of Ciliary Proteins by BioID.
Therapeutic potential of HUC-MSC-exos primed with IFN-γ against LPS-induced acute lung injury.
Ovarian ferroptosis induced by androgen is involved in pathogenesis of PCOS.
Huaju Xiaoji Formula Regulates ERS-lncMGC/miRNA to Enhance the Renal Function of Hypertensive Diabetic Mice with Nephropathy.
WTAP Mediated N6-methyladenosine RNA Modification of ELF3 Drives Cellular Senescence by Upregulating IRF8.
PARP1 Promotes Heart Regeneration and Cardiomyocyte Proliferation.
Lysozyme promotes renal fibrosis through the JAK/STAT3 signal pathway in diabetic nephropathy.
Pan-cancer analysis of PSCA that is associated with immune infiltration and affects patient prognosis.
Echinatin attenuates acute lung injury and inflammatory responses via TAK1-MAPK/NF-κB and Keap1-Nrf2-HO-1 signaling pathways in macrophages.
Rauwolfia polysaccharide can inhibit the progress of ulcerative colitis through NOS2-mediated JAK2/STAT3 pathway.
circTADA2A inhibited SLC38A1 expression and suppresses melanoma progression through the prevention of CNBP trans-activation.
Functional analysis of ESM1 by shRNA-mediated knockdown of its expression in papillary thyroid cancer cells.
FBLN5 was Regulated by PRDM9, and Promoted Senescence and Osteogenic Differentiation of Human Periodontal Ligament Stem Cells.
Downregulation of the CD151 protects the cardiac function by the crosstalk between the endothelial cells and cardiomyocytes via exosomes.
METTL3-mediated methylation of CYP2C19 mRNA may aggravate clopidogrel resistance in ischemic stroke patients.
KAT2A changes the function of endometrial stromal cells via regulating the succinylation of ENO1.
Silencing KLF6 Alleviates Cigarette Smoke Extract-Induced Mitochondrial Dysfunction in Bronchial Epithelial Cells by SIRT4 Upregulation.
Lipid-Based Self-Microemulsion of Niclosamide Achieved Enhanced Oral Delivery and Anti-Tumor Efficacy in Orthotopic Patient-Derived Xenograft of Hepatocellular Carcinoma in Mice.
A convenient model of serum-induced reactivity of human astrocytes to investigate astrocyte-derived extracellular vesicles.
Huang Gan Formula Alleviates Systemic Inflammation and Uremia in Adenine-Induced Chronic Kidney Disease Rats May Associate with Modification of Gut Microbiota and Colonic Microenvironment.
Identification of Transcriptomic Signatures of Pancreatic Ductal Adenocarcinoma-Derived Exosomes That Promote Macrophage M2 Polarization and Predict Prognosis: S100A9 Reveals Tumor Progression.
Trimethylamine N-oxide aggravates vascular permeability and endothelial cell dysfunction under diabetic condition: in vitro and in vivo study.
Comprehensive Analysis of Fatty Acid Metabolism in Diabetic Nephropathy from the Perspective of Immune Landscapes, Diagnosis and Precise Therapy.
Progerin Inhibits the Proliferation and Migration of Melanoma Cells by Regulating the Expression of Paxillin.
NAD-Dependent Protein Deacetylase Sirtuin-1 Mediated Mitophagy Regulates Early Brain Injury After Subarachnoid Hemorrhage.
Consequences of GMPPB deficiency for neuromuscular development and maintenance.
Prognostic value of RNF113A shows a correlation with immune infiltrates in colorectal cancer.
ASB6 as an Independent Prognostic Biomarker for Colorectal Cancer Progression Involves Lymphatic Invasion and Immune Infiltration.
KRT80 Promotes Lung Adenocarcinoma Progression and Serves as a Substrate for VCP.
FEN1 Promotes Hepatocellular Carcinoma Progression by Activating Cell Cycle Transition from G2 To M Phase.
Berberine-mediated Ferroptosis through System Xc(-)/GSH/GPX4 Axis Inhibits Metastasis of Nasopharyngeal Carcinoma.
HSPB8 Facilitates the Oncogenesis and Advancement of Bladder Cancer via Activation of HSP27.
IGFBP5, as a Prognostic Indicator Promotes Tumor Progression and Correlates with Immune Microenvironment in Glioma.
Polygonatum cyrtonema polysaccharides reshape the gut microbiota to ameliorate dextran sodium sulfate-induced ulcerative colitis in mice.
Inhibition of NNMT enhances drug sensitivity in lung cancer cells through mediation of autophagy.
Identification of host proteins interacting with the E protein of porcine epidemic diarrhea virus.
Research on the metabolic regulation mechanism of Yangyin Qingfei decoction plus in severe pneumonia caused by Mycoplasma pneumoniae in mice.
PCBP1 interacts with the HTLV-1 Tax oncoprotein to potentiate NF-κB activation.
Inhibition of ACOX1 enhances the therapeutic efficacy of obeticholic acid in treating non-alcoholic fatty liver disease and mitigates its lipotoxicity.
Identification of potential anti-inflammatory components in Moutan Cortex by bio-affinity ultrafiltration coupled with ultra-performance liquid chromatography mass spectrometry.
Identification of potential novel N6-methyladenosine effector-related lncRNA biomarkers for serous ovarian carcinoma: a machine learning-based exploration in the framework of 3P medicine.
Differences in F pocket impact on HLA I genetic associations with autoimmune diabetes.
Delineation of renal protein profiles in aristolochic acid I-induced nephrotoxicity in mice by label-free quantitative proteomics.
Genistein is effective in inhibiting Orf virus infection in vitro by targeting viral RNA polymerase subunit RPO30 protein.
Transcriptome-wide 1-methyladenosine functional profiling of messenger RNA and long non-coding RNA in bladder cancer.
Exosomal miR-223-3p from bone marrow mesenchymal stem cells targets HDAC2 to downregulate STAT3 phosphorylation to alleviate HBx-induced ferroptosis in podocytes.
USP50 regulates NLRP3 inflammasome activation in duodenogastric reflux-induced gastric tumorigenesis.
Identification and validation of UBE2B as a prognostic biomarker promoting the development of esophageal carcinomas.
FSH induces EMT in ovarian cancer via ALKBH5-regulated Snail m6A demethylation.
Cancer-associated fibroblasts reprogram cysteine metabolism to increase tumor resistance to ferroptosis in pancreatic cancer.
SGK3 promotes vascular calcification via Pit-1 in chronic kidney disease.
YY1-induced lncRNA00511 promotes melanoma progression via the miR-150-5p/ADAM19 axis.
NRF2 promotes radiation resistance by cooperating with TOPBP1 to activate the ATR-CHK1 signaling pathway.
Arsenic trioxide suppresses lung adenocarcinoma stem cell stemness by inhibiting m6A modification to promote ferroptosis.
Comprehensive analysis of peroxisome proliferator-activated receptors to predict the drug resistance, immune microenvironment, and prognosis in stomach adenocarcinomas.
Low-intensity pulsed ultrasound promotes the osteogenesis of mechanical force-treated periodontal ligament cells via Piezo1.
Exercise attenuates high-fat diet-induced PVAT dysfunction through improved inflammatory response and BMP4-regulated adipose tissue browning.
Bioinformatics analysis and experimental verification of TIGD1 in non-small cell lung cancer.
Small extracellular vesicles from irradiated lung epithelial cells promote the activation of fibroblasts in pulmonary fibrosis.
PIEZO1 mechanically regulates the antitumour cytotoxicity of T lymphocytes.
Identification of TUBB2A as a Cancer-Immunity Cycle-Related Therapeutic Target in Triple-Negative Breast Cancer.
CircPRRC2C Promotes the Oncogenic Phenotypes of Laryngeal Squamous Cell Carcinoma Cells via MiR-136-5p/HOXD11 Axis.
Quercetin Ameliorates Cognitive Impairment in Depression by Targeting HSP90 to Inhibit NLRP3 Inflammasome Activation.
Enhancing Fat Transplantation Efficiency in a Mouse Model through Pretreatment of Adipose-Derived Stem Cells with RIP3 Inhibitors.
Locationally activated PRP via an injectable dual-network hydrogel for endometrial regeneration.
Counteracting TGM2 by a Fibroin peptide ameliorated Adriamycin-induced nephropathy via regulation of lipid metabolism through PANX1-PPAR α/PANK1 pathway.
CTSD upregulation as a key driver of spinal ligament abnormalities in spinal stenosis.
Naringenin relieves paclitaxel-induced pain by suppressing calcitonin gene-related peptide signalling and enhances the anti-tumour action of paclitaxel.
The CK1ε/SIAH1 axis regulates AXIN1 stability in colorectal cancer cells.
Sestrin2 remedies neuroinflammatory response by inhibiting A1 astrocyte conversion via autophagy.
Identification of prognostic biomarkers for cholangiocarcinoma by combined analysis of molecular characteristics of clinical MVI subtypes and molecular subtypes.
Uremic Toxin Receptor AhR Facilitates Renal Senescence and Fibrosis via Suppressing Mitochondrial Biogenesis.
TolDC Restores the Balance of Th17/Treg via Aryl Hydrocarbon Receptor to Attenuate Colitis.
Investigation of crucial genes and mitochondrial function impairment in diabetic cardiomyopathy.
Role of endothelial Raptor in abnormal arteriogenesis after lower limb ischaemia in type 2 diabetes.
PDGFRα signaling regulates Srsf3 transcript binding to affect PI3K signaling and endosomal trafficking.
PPP1r18 promotes tumor progression in esophageal squamous cell carcinoma by regulating the calcineurin-mediated ERK pathway.
Identification of novel biomarker hsa_circ_0003914 for rheumatoid arthritis from plasma exosomes.
Nicotine induces senescence in spermatogonia stem cells by disrupting homeostasis between circadian oscillation and rhythmic mitochondrial dynamics via the SIRT6/Bmal1 pathway.
LPAR6 Participates in Neuropathic Pain by Mediating Astrocyte Cells via ROCK2/NF-κB Signal Pathway.
The Long Non-Coding RNA NR3C2-8:1 Promotes p53-Mediated Apoptosis through the miR-129-5p/USP10 Axis in Amyotrophic Lateral Sclerosis.
Deletion of Tgm2 suppresses BMP-mediated hepatocyte-to-cholangiocyte metaplasia in ductular reaction.
Quercetin Regulates Microglia M1/M2 Polarization and Alleviates Retinal Inflammation via ERK/STAT3 Pathway.
High Expression of miR-6785-5p in the Serum Exosomes of Psoriasis Patients Alleviates Psoriasis-Like Skin Damage by Interfering with the MNK2/p-eIF4E Axis in Keratinocytes.
Identification of key pathways in zirconia/dental pulp stem cell composite scaffold-mediated macrophage polarization through transcriptome sequencing.
LncRNA SLC9A3-AS1 knockdown increases the sensitivity of liver cancer cell to triptolide by regulating miR-449b-5p-mediated glycolysis.
Circadian gene CLOCK accelerates atherosclerosis by promoting endothelial autophagy.
Dexmedetomidine attenuates ferroptosis by Keap1-Nrf2/HO-1 pathway in LPS-induced acute kidney injury.
Thy1-ApoE4/C/EBPβ double transgenic mice act as a sporadic model with Alzheimer's disease.
LncRNA MFRL regulates the phenotypic switch of vascular smooth muscle cells to attenuate arterial remodeling by encoding a novel micropeptide MFRLP.
A model of alcoholic liver disease based on different hepatotoxics leading to liver cancer.
LINC00963 Promotes Cisplatin Resistance in Esophageal Squamous Cell Carcinoma by Interacting with miR-10a to Upregulate SKA1 Expression.
Eml1 promotes axonal growth by enhancing αTAT1-mediated microtubule acetylation.
LncRNA H19/miR-107 regulates endothelial progenitor cell pyroptosis and promotes flow recovery of lower extremity ischemia through targeting FADD.
FTO alleviated ferroptosis in septic cardiomyopathy via mediating the m6A modification of BACH1.
UBE2C orchestrates bone formation through stabilization of SMAD1/5.
Identification of TACSTD2 as novel therapeutic targets for cisplatin-induced acute kidney injury by multi-omics data integration.
Plasma-derived exosomal miRNA profiles reveal potential epigenetic pathogenesis of premature ovarian failure.
The regulation of GSH/GPX4-mediated lipid accumulation confirms that schisandra polysaccharides should be valued equally as lignans.
Elevated DNA Damage without signs of aging in the short-sleeping Mexican Cavefish.
3'-Deoxyadenosin alleviates methamphetamine-induced aberrant synaptic plasticity and seeking behavior by inhibiting the NLRP3 inflammasome.
miR-1180 Targets FXYD5 to Regulate Pancreatic Cancer Cells Migration and Invasion.
Gene Profiling of Circular RNAs in Keloid-prone Individuals and ceRNA Network Construction During Wound Healing.
Metformin attenuates PM(2.5)-induced oxidative stress by inhibiting the AhR/CYP1A1 pathway in proximal renal tubular epithelial cells.
Pathologic TDP-43 downregulates myelin gene expression in the monkey brain.
Pharmacological inhibition of astrocytic transglutaminase 2 facilitates the expression of a neurosupportive astrocyte reactive phenotype in association with increased histone acetylation.
OSMR is a potential driver of inflammation in amyotrophic lateral sclerosis.
Itaconate inhibits corticosterone-induced necroptosis and neuroinflammation via up-regulating menin in HT22 cells.
Syk-dependent homologous recombination activation promotes cancer resistance to DNA targeted therapy.
Human papillomavirus-16 E6 activates the pentose phosphate pathway to promote cervical cancer cell proliferation by inhibiting G6PD lactylation.
Highly Expressed Z-DNA Binding Protein 1 in Esophageal Cancer Promotes Tumor Growth.
The Effect of Coenzyme Q10 Supplementation on Bile Acid Metabolism: Insights from Network Pharmacology, Molecular Docking, and Experimental Validation.
Effects of the ferroptosis inducer erastin on osteogenic differentiation and biological pathways of primary osteoblasts.
YTHDF1 promotes the viability and self‑renewal of glioma stem cells by enhancing LINC00900 stability.
Prokineticin-2 Participates in Chronic Constriction Injury-Triggered Neuropathic Pain and Anxiety via Regulated by NF-κB in Nucleus Accumbens Shell in Rats.
p53 suppresses the inflammatory response following respiratory syncytial virus infection by inhibiting TLR2.
Homocysteine-potentiated Kelch-like ECH-associated protein 1 promotes senescence of neuroblastoma 2a cells via inhibiting ubiquitination of β-catenin.
Butyrate increases methylglyoxal production through regulation of the JAK2/Stat3/Nrf2/Glo1 pathway in castration‑resistant prostate cancer cells.
Lnc-Clic5 as a sponge for miR-212-5p to inhibit cow barn PM(2.5)-induced apoptosis in rat alveolar macrophages.
PFOS Elicits Cytotoxicity in Neuron Through Astrocyte-Derived CaMKII-DLG1 Signaling In Vitro Rat Hippocampal Model.
LRP8 promotes tumorigenesis in ovarian cancer through inhibiting p53 signaling.
Mangiferin alleviates diabetic pulmonary fibrosis in mice via inhibiting endothelial-mesenchymal transition through AMPK/FoxO3/SIRT3 axis.
Characteristics of spatial protein expression in the mouse cochlear sensory epithelia: Implications for age-related hearing loss.
A Mettl16/m(6)A/mybl2b/Igf2bp1 axis ensures cell cycle progression of embryonic hematopoietic stem and progenitor cells.
Dynamic relationship among extracellular matrix and body wall cells in Hirudo verbana morphogenesis.
Favorable osteogenic activity of vericiguat doped in β-tricalcium phosphate: In vitro and in vivo studies.
Tetramerization of pyruvate kinase M2 attenuates graft-versus-host disease by inhibition of Th1 and Th17 differentiation.
Selective Organ-Targeting Hafnium Oxide Nanoparticles with Multienzyme-Mimetic Activities Attenuate Radiation-Induced Tissue Damage.
Construction of functional neural network tissue combining CBD-NT3-modified linear-ordered collagen scaffold and TrkC-modified iPSC-derived neural stem cells for spinal cord injury repair.
Combining large-spot low-fluence 1064-nm and fractional 1064-nm picosecond lasers for promoting protective melanosome autophagy via the PI3K/Akt/mTOR signalling pathway for the treatment of melasma.
Dual-inhibition of NAMPT and PAK4 induces anti-tumor effects in 3D-spheroids model of platinum-resistant ovarian cancer.
SLC25A3 negatively regulates NLRP3 inflammasome activation by restricting the function of NLRP3.
Epstein-Barr virus suppresses N(6)-methyladenosine modification of TLR9 to promote immune evasion.
The tumor suppressor NF2 modulates TEAD4 stability and activity in Hippo signaling via direct interaction.
Electroacupuncture regulates Rab5a-mediating NGF transduction to improve learning and memory ability in the early stage of AD mice.
Inhibition of ADORA3 promotes microglial phagocytosis and alleviates chronic ischemic white matter injury.
Regulation of osteoclast differentiation and inflammatory signaling by TCF8 in periodontitis.
LINC00525 promotes tumour growth and epithelial-mesenchymal transition as an oncogene in oral squamous cell carcinoma.
CDK5-mediated rearrangement of vimentin during Duck Tembusu virus infection inhibits viral replication.
NMDA receptor within nucleus accumbens shell regulates propofol self-administration through D1R/ERK/CREB signalling pathway.
Glutathione peroxidase 4 restrains temporomandibular joint osteoarthritis progression by inhibiting ferroptosis.
Decreased intranuclear cardiac troponin I impairs cardiac autophagy through FOS/ATG5 in ageing hearts.
Epigenetic regulation by KDM5A mediates the effects of prenatal PM(2.5) exposure on hippocampal development and synaptic integrity through the Shh signaling pathway.
Biomass fuels related-PM(2.5) promotes lung fibroblast-myofibroblast transition through PI3K/AKT/TRPC1 pathway.
Nicotinamide ribose ameliorates myocardial ischemia/reperfusion injury by regulating autophagy and regulating oxidative stress.
LncRNA lncMGR regulates skeletal muscle development and regeneration by recruiting CDK9 and sponging miRNAs.
LPCAT1-mediated membrane phospholipid remodelling promotes ferroptosis evasion and tumour growth.
Endurance training increases mitochondrial myoglobin and enhances its interaction with complex IV in rat plantaris muscle.
KLF13 promotes VSMCs phenotypic dedifferentiation by directly binding to the SM22α promoter.
circUSP13 facilitates the fast-to-slow myofiber shift via the MAPK/ERK signaling pathway in goat skeletal muscles.
m(6)A-induced TRIB3 regulates Hippo pathway through interacting with LATS1 to promote the progression of lung adenocarcinoma.
N-homocysteinylation of DJ-1 promotes neurodegeneration in Parkinson's disease.
PLCE1 enhances mitochondrial dysfunction to promote GSDME-mediated pyroptosis in doxorubicin-induced cardiotoxicity.
Human disease-causing mutations result in loss of leiomodin 2 through nonsense-mediated mRNA decay.
Conditioned medium from human dental pulp stem cells treats spinal cord injury by inhibiting microglial pyroptosis.
Untargeted metabolomic reveals the changes in muscle metabolites of mice during exercise recovery and the mechanisms of whey protein and whey protein hydrolysate in promoting muscle repair.
Interferon-α induces differentiation of cancer stem cells and immunosuppression in hepatocellular carcinoma by upregulating CXCL8 secretion.
Sacubitril/Valsartan inhibits M1 type macrophages polarization in acute myocarditis by targeting C-type natriuretic peptide.
Resveratrol protects against myocardial ischemic injury in obese mice via activating SIRT3/FOXO3a signaling pathway and restoring redox homeostasis.
DMC-siERCC2 hybrid nanoparticle enhances TRAIL sensitivity by inducing cell cycle arrest for glioblastoma treatment.
Cornus officinalis with high pressure wine steaming enhanced anti-hepatic fibrosis: Possible through SIRT3-AMPK axis.
Pirfenidone alleviates fibrosis by acting on tumour-stroma interplay in pancreatic cancer.
Proton pump inhibitors stabilize the expression of PD-L1 on cell membrane depending on the phosphorylation of GSK3β.
A comprehensive comparison of molecular and phenotypic profiles between hepatitis B virus (HBV)-infected and non-HBV-infected hepatocellular carcinoma by multi-omics analysis.
Urolithin A Hijacks ERK1/2-ULK1 Cascade to Improve CD8(+) T Cell Fitness for Antitumor Immunity.
Molybdenum and cadmium co-induce apoptosis and ferroptosis through inhibiting Nrf2 signaling pathway in duck (Anas platyrhyncha) testes.
Knocking-down long non-coding RNA LINC01094 prohibits chondrocyte apoptosis via regulating microRNA-577/metal-regulatory transcription factor 1 axis.
Design, Synthesis, and Biological Evaluation of Novel EGFR PROTACs Targeting C797S Mutation.
Discovery of a Potent Dual Son of Sevenless 1 (SOS1) and Epidermal Growth Factor Receptor (EGFR) Inhibitor for the Treatment of Prostate Cancer.
Gemfibrozil-Platinum(IV) Precursors for New Enhanced-Starvation and Chemotherapy In Vitro and In Vivo.
Autologous patient-derived exhausted nano T-cells exploit tumor immune evasion to engage an effective cancer therapy.
Mesencephalic astrocyte-derived neurotrophic factor ameliorates inflammatory response in polycystic ovary syndrome via inhibiting TLR4-NF-κB-NLRP3 pathway.
Gut bacteria-driven homovanillic acid alleviates depression by modulating synaptic integrity.
Disruption of maternal vascular remodeling by a fetal endoretrovirus-derived gene in preeclampsia.
Polymorphism rs2327430 in TCF21 predicts the risk and prognosis of gastric cancer by affecting the binding between TFAP2A and TCF21.
Identification of immunogenic cell death-related damage-related molecular patterns (DAMPs) to predict outcomes in patients with head and neck squamous cell carcinoma.
Esaxerenone Inhibits Interferon-γ Induced Pyroptosis of Macrophages in the Lungs of Aldosterone-treated Mice.
Dendritic-cell-targeting virus-like particles as potent mRNA vaccine carriers.
Varespladib mitigates acute liver injury via suppression of excessive mitophagy on Naja atra envenomed mice by inhibiting PLA(2).
A TBK1 variant causes autophagolysosomal and motoneuron pathology without neuroinflammation in mice.
Modified Lichong decoction intervenes in colorectal cancer by modulating the intestinal flora and the Wnt/β-catenin signaling pathway.
Activation of CaMKII/HDAC4 by SDF1 contributes to pulmonary arterial hypertension via stabilization Runx2.
Maternal prednisone exposure during pregnancy elevates susceptibility to osteoporosis in female offspring: The role of mitophagy/FNDC5 alteration in skeletal muscle.
Design, synthesis, and evaluation of novel quindoline derivatives with fork-shaped side chains as RNA G-quadruplex stabilizers for repressing oncogene NRAS translation.
Design, synthesis and evaluation of a pyrazolo[3,4-d]pyrimidine derivative as a novel and potent TGFβ1R1 inhibitor.
IRF7 from the black flying fox induces a STAT1-independent ISG response in unstimulated cell lines that protects against diverse RNA viruses.
Vasorin promotes endothelial differentiation of glioma stem cells via stimulating the transcription of VEGFR2.
Melatonin suppresses atherosclerosis by ferroptosis inhibition via activating NRF2 pathway.
Methyl-CpG-binding protein 2 regulates CYP27A1-induced myometrial contraction during preterm labor.
Genkwanin alleviates intervertebral disc degeneration via regulating ITGA2/PI3K/AKT pathway and inhibiting apoptosis and senescence.
Ivermectin ameliorates acute myocarditis via the inhibition of importin-mediated nuclear translocation of NF-κB/p65.
FOXF1 reverses lung fibroblasts transdifferentiation via inhibiting TGF-β/SMAD2/3 pathway in silica-induced pulmonary fibrosis.
Elevated microRNA-214-3p level ameliorates neuroinflammation after spinal cord ischemia-reperfusion injury by inhibiting Nmb/Cav3.2 pathway.
The therapeutic effect and targets of herba Sarcandrae on breast cancer and the construction of a prognostic signature consisting of inflammation-related genes.
LC-MS-based rheumatoid arthritis serum metabolomics reveals the role of deoxyinosine in attenuating collagen-induced arthritis in mice.
Armcx1 Reduces Neurological Damage Via a Mitochondrial Transport Pathway Involving Miro1 After Traumatic Brain Injury.
Targeting the molecular chaperone CCT2 inhibits GBM progression by influencing KRAS stability.
SOD1-high fibroblasts derived exosomal miR-3960 promotes cisplatin resistance in triple-negative breast cancer by suppressing BRSK2-mediated phosphorylation of PIMREG.
The Mediator Med23 controls a transcriptional switch for muscle stem cell proliferation and differentiation in muscle regeneration.
Paclitaxel-induced Immune Dysfunction and Activation of Transcription Factor AP-1 Facilitate Hepatitis B Virus Replication.
Nur77 inhibition of β-catenin expression mediates Hepatoblastoma progression and enhances cisplatin's therapeutic effect.
Accumulated LPS induced by colitis altered the activities of vitamin D-metabolizing hydroxylases and decreased the generation of 25-hydroxyvitamin D.
Usp14 deficiency removes α-synuclein by regulating S100A8/A9 in Parkinson's disease.
Activation of Nrf2/HO-1 signaling pathway exacerbates cholestatic liver injury.
Design of FK866-Based Degraders for Blocking the Nonenzymatic Functions of Nicotinamide Phosphoribosyltransferase.
NEK2 contributes to radioresistance in esophageal squamous cell carcinoma by inducing protective autophagy via regulating TRIM21.
APC/C-regulated CPT1C promotes tumor progression by upregulating the energy supply and accelerating the G1/S transition.
Pacidusin B isolated from Phyllanthus acidus triggers ferroptotic cell death in HT1080 cells.
RNA-binding properties orchestrate TDP-43 homeostasis through condensate formation in vivo.
Activity reconstitution of Kre33 and Tan1 reveals a molecular ruler mechanism in eukaryotic tRNA acetylation.
WSB1/2 target chromatin-bound lysine-methylated RelA for proteasomal degradation and NF-κB termination.
Methylation-regulated tumor suppressor gene PDE7B promotes HCC invasion and metastasis through the PI3K/AKT signaling pathway.
TRIM65 promotes renal cell carcinoma through ubiquitination and degradation of BTG3.
Exposure to Selenomethionine and Selenocystine Induces Redox-Mediated ER Stress in Normal Breast Epithelial MCF-10A Cells.
Dexamethasone-Integrated Mesenchymal Stem Cells for Systemic Lupus Erythematosus Treatment via Multiple Immunomodulatory Mechanisms.
Implications of LAG3 and CTLA4 immune checkpoints beyond PD-1/PD-L1 as a potential target in determining the prognosis of uveal melanoma patients.
Antiviral Activities of Heparan Sulfate Mimetic RAFT Polymers Against Mosquito-borne Viruses.
Ginsenoside Rk1 improves endothelial function in diabetes through activating peroxisome proliferator-activated receptors.
MILIP Binding to tRNAs Promotes Protein Synthesis to Drive Triple-Negative Breast Cancer.
TRIM14 suppressed the progression of NSCLC via hexosamine biosynthesis pathway.
Fluoride Induces Neurocytotoxicity by Disrupting Lysosomal Iron Metabolism and Membrane Permeability.
Aurora-A condensation mediated by BuGZ aids its mitotic centrosome functions.
The acetylation of MDH1 and IDH1 is associated with energy metabolism in acute liver failure.
Positive Effect of 6-Gingerol on Functional Plasticity of Microglia in a rat Model of LPS-induced Depression.
TRIM37 is a primate-specific E3 ligase for Huntingtin and accounts for the striatal degeneration in Huntington's disease.
An ATP13A1-assisted topogenesis pathway for folding multi-spanning membrane proteins.
CRTAC1 identified as a promising diagnosis and prognostic biomarker in lung adenocarcinoma.
Alnustone promotes megakaryocyte differentiation and platelet production via the interleukin-17A/interleukin-17A receptor/Src/RAC1/MEK/ERK signaling pathway.
Alleviative effects of the parthenolide derivative ACT001 on insulin resistance induced by sodium propionate combined with a high-fat diet and its potential mechanisms.
PABPC1L Induces IDO1 to Promote Tryptophan Metabolism and Immune Suppression in Renal Cell Carcinoma.
Deficiency of nucleosome-destabilizing factor GLYR1 dampens spermatogenesis in mice.
Roles of AhR/CYP1s signaling pathway mediated ROS production in uremic cardiomyopathy.
Metformin induction of heat shock factor 1 activation and the mitochondrial unfolded protein response alleviate cardiac remodeling in spontaneously hypertensive rats.
Early life stage exposure to fenbuconazole causes multigenerational cardiac developmental defects in zebrafish and potential reasons.
Stenotrophomonas maltophilia contributes to smoking-related emphysema through IRF1-triggered PANoptosis of alveolar epithelial cells.
Upregulated dual oxidase 1-induced oxidative stress and caspase-1-dependent pyroptosis reflect the etiologies of heart failure.
Network pharmacology combined with lipidomics to reveal the regulatory effects and mechanisms of Kangzao granules in the hypothalamus of rats with central precocious puberty.
Knockdown of trem2 promotes proinflammatory microglia and inhibits glioma progression via the JAK2/STAT3 and NF-κB pathways.
MiR-21-5p modulates LPS-induced acute injury in alveolar epithelial cells by targeting SLC16A10.
Network pharmacology-based analysis on the key mechanisms of Yiguanjian acting on chronic hepatitis.
Pseudorabies virus usurps non-muscle myosin heavy chain IIA to dampen viral DNA recognition by cGAS for antagonism of host antiviral innate immunity.
25-Hydroxycholesterol regulates lysosome AMP kinase activation and metabolic reprogramming to educate immunosuppressive macrophages.
PLAG1 interacts with GPX4 to conquer vulnerability to sorafenib induced ferroptosis through a PVT1/miR-195-5p axis-dependent manner in hepatocellular carcinoma.
KAP1 stabilizes MYCN mRNA and promotes neuroblastoma tumorigenicity by protecting the RNA m(6)A reader YTHDC1 protein degradation.
The Hippo pathway terminal effector TAZ/WWTR1 mediates oxaliplatin sensitivity in p53 proficient colon cancer cells.
The crosstalk between macrophages and cancer cells potentiates pancreatic cancer cachexia.
Identification and verification of a novel signature that combines cuproptosis-related genes with ferroptosis-related genes in osteoarthritis using bioinformatics analysis and experimental validation.
Synergistic effect of mesenchymal stem cell-derived extracellular vesicle and miR-137 alleviates autism-like behaviors by modulating the NF-κB pathway.
Tumors cells with mismatch repair deficiency induce hyperactivation of pyroptosis resistant to cell membrane damage but are more sensitive to co-treatment of IFN-γ and TNF-α to PANoptosis.
Mesencephalic astrocyte-derived neurotrophic factor inhibits cervical cancer progression via regulating macrophage phenotype.
Multi-omics integration highlights the role of ubiquitination in endometriosis fibrosis.
Glutamine Metabolism Heterogeneity in Glioblastoma Unveils an Innovative Combination Therapy Strategy.
ω3-PUFA alleviates neuroinflammation by upregulating miR-107 targeting PIEZO1/NFκB p65.
Ischemia-inhibited ferric chelate reductase 1 improves ferroptosis-mediated intestinal ischemia injury via Hippo signaling.
A unique circ_0067716/EIF4A3 double-negative feedback loop impacts malignant transformation of human bronchial epithelial cells induced by benzo(a)pyrene.
Pharmacological suppression of HHLA2 glycosylation restores anti-tumor immunity in colorectal cancer.
Cytotoxic withanolides from the stems and leaves of Physalis ixocarpa.
Nuclear AGO2 promotes myocardial remodeling by activating ANKRD1 transcription in failing hearts.
Hnrnpk protects against osteoarthritis through targeting WWC1 mRNA and inhibiting Hippo signaling pathway.
DDX18 Facilitates the Tumorigenesis of Lung Adenocarcinoma by Promoting Cell Cycle Progression through the Upregulation of CDK4.
Eplerenone reduces lymphangiogenesis in the contralateral kidneys of UUO rats.
Kaempferol alleviates adipose tissue inflammation and insulin resistance in db/db mice by inhibiting the STING/NLRP3 signaling pathway.
UMP-CMP kinase 2 inhibits ZIKV replication through activation of type I IFN signaling pathway.
microRNA profilings identify plasma biomarkers and targets associated with pediatric epilepsy patients.
Platelet rich plasma alleviates endometritis induced by lipopolysaccharide in mice via inhibiting TLR4/NF-κB signaling pathway.
Primate Model Carrying LMNA Mutation Develops Dilated Cardiomyopathy.
Spinster homolog 2 reduces malignancies of glioblastoma via PTEN/PI3K/AKT pathway.
Lrg1 silencing attenuates ischemia-reperfusion renal injury by regulating autophagy and apoptosis through the TGFβ1- Smad1/5 signaling pathway.
Tumor-acquired somatic mutation affects conformation to abolish ABCG2-mediated drug resistance.
Methylation of GPRC5A promotes liver metastasis and docetaxel resistance through activating mTOR signaling pathway in triple negative breast cancer.
NDRG1 overcomes resistance to immunotherapy of pancreatic ductal adenocarcinoma through inhibiting ATG9A-dependent degradation of MHC-1.
Dynamics of N6-methyladenosine modification during aging and their potential roles in the degeneration of intervertebral disc.
M6PR interacts with the HA2 subunit of influenza A virus to facilitate the fusion of viral and endosomal membranes.
HDAC inhibitors target IRS4 to enhance anti‑AR therapy in AR‑positive triple‑negative breast cancer.
CCL2 Knockdown Attenuates Inflammatory Response After Spinal Cord Injury Through the PI3K/Akt Signaling Pathway: Bioinformatics Analysis and Experimental Validation.
Knockdown of ANGPTL4 inhibits adipogenesis of preadipocyte via autophagy.
Bilirubin impairs neuritogenesis and synaptogenesis in NSPCs by downregulating NMDAR-CREB-BDNF signaling.
RNA m(5)C modification upregulates E2F1 expression in a manner dependent on YBX1 phase separation and promotes tumor progression in ovarian cancer.
MitoQ Alleviated PM(2.5) Induced Pulmonary Epithelial Cells Injury by Inhibiting Mitochondrial-Mediated Apoptosis.
Regulator of G protein signalling 18 promotes osteocyte proliferation by activating the extracellular signal‑regulated kinase signalling pathway.
Ferrostatin‑1 alleviates liver injury via decreasing ferroptosis following ricin toxin poisoning in rat.
Quercetin alleviates the toxicity of difenoconazole to the respiratory system of carp by reducing ROS accumulation and maintaining mitochondrial dynamic balance.
POLE2 knockdown suppresses lymphoma progression via downregulating Wnt/β-catenin signaling pathway.
Targeting autophagy overcomes cancer-intrinsic resistance to CAR-T immunotherapy in B-cell malignancies.
Pan-cancer analysis of ABCC1 as a potential prognostic and immunological biomarker.
High expression of B7-H3 on monocyte/macrophages in tumor microenvironment promotes lung cancer progression by inhibiting apoptosis.
Age-, sex- and proximal-distal-resolved multi-omics identifies regulators of intestinal aging in non-human primates.
Phenylacetyl glutamine (PAGln) enhances cardiomyocyte death after myocardial infarction through β1 adrenergic receptor.
1-Benzylimidazole attenuates the stemness of breast cancer cells through partially targeting CYP4Z1.
Ferrostatin-1 improves neurological impairment induced by ischemia/reperfusion injury in the spinal cord through ERK1/2/SP1/GPX4.
Transcutaneous electrical acupoint stimulation attenuated neuroinflammation and oxidative stress by activating SIRT1-induced signaling pathway in MCAO/R rat models.
Peroxiredoxin-1 as a molecular chaperone that regulates glutathione S-transferase P1 activity and drives mutidrug resistance in ovarian cancer cells.
A novel antigenic epitope identified on the accessory protein NS6 of porcine deltacoronavirus.
Transcription factor MYB8 regulates iron deficiency stress response in Arabidopsis.
Structural basis for specific DNA sequence recognition by the transcription factor NFIL3.
The splicing factor Prpf31 is required for hematopoietic stem and progenitor cell expansion during zebrafish embryogenesis.
Human umbilical cord mesenchymal stem cell-derived exosomes attenuate neuroinflammation and oxidative stress through the NRF2/NF-κB/NLRP3 pathway.
Inhibition of HDAC6 promotes microvascular endothelial cells to phagocytize myelin debris and reduces inflammatory response to accelerate the repair of spinal cord injury.
RNA 5-Methylcytosine Regulator NSUN3 promotes tumor progression through regulating immune infiltration in head and neck squamous cell carcinoma.
SOD2 confers anlotinib resistance via regulation of mitochondrial damage in OSCC.
CD24 blockade promotes anti-tumor immunity in oral squamous cell carcinoma.
Electroacupuncture Attenuates Ventilator-Induced Lung Injury by Modulating the Nrf2/HO-1 Pathway.
MicroRNA-194-5p/Heparin-binding EGF-like growth factor signaling mediates dexamethasone-induced activation of pseudorabies virus in rat pheochromocytoma cells.
SGLT2i improves kidney senescence by down-regulating the expression of LTBP2 in SAMP8 mice.
Rhizoma Paridis saponins attenuate Gram-negative bacteria-induced inflammatory acne by binding to KEAP1 and modulating Nrf2 and MAPK pathways.
RNF125‑mediated ubiquitination of MCM6 regulates the proliferation of human liver hepatocellular carcinoma cells.
Novel MSH2 and TSC2 variants in a Chinese family with Lynch syndrome and their synergistic impact in urothelial carcinoma.
Precision targeting of CuET overload to disrupt mitochondrial unfolded protein response by integrated liposome.
Prenatal EGCG consumption impacts hepatic glycogen synthesis and lipid metabolism in adult mice.
LncRNA XXYLT1-AS2 promotes tumor progression via autophagy inhibition through ubiquitinated degradation of TFEB in hepatocellular carcinoma.
Drosophila TMEM63 and mouse TMEM63A are lysosomal mechanosensory ion channels.
Hyperfunction of post-synaptic density protein 95 promotes seizure response in early-stage aβ pathology.
A lncRNA Dleu2-encoded peptide relieves autoimmunity by facilitating Smad3-mediated Treg induction.
M1 Macrophage-Derived Exosome LncRNA PVT1 Promotes Inflammation and Pyroptosis of Vascular Smooth Muscle Cells in Abdominal Aortic Aneurysm by Inhibiting miR-186-5p and Regulating HMGB1.
Pharmacological induction of autophagy reduces inflammation in macrophages by degrading immunoproteasome subunits.
SMAD7 expression in CAR-T cells improves persistence and safety for solid tumors.
CDK12 inhibition upregulates ATG7 triggering autophagy via AKT/FOXO3 pathway and enhances anti-PD-1 efficacy in colorectal cancer.
Alpha-Emitter Radium-223 Induces STING-Dependent Pyroptosis to Trigger Robust Antitumor Immunity.
ALIX and TSG101 are essential for cellular entry and replication of two porcine alphacoronaviruses.
UBE3C tunes autophagy via ATG4B ubiquitination.
CKLF induces microglial activation via triggering defective mitophagy and mitochondrial dysfunction.
Vitamin D Receptor Activation Reduces Hepatic Inflammation via Enhancing Macrophage Autophagy in Cholestatic Mice.
A high concentrate diet inhibits forkhead box protein A2 expression, and induces oxidative stress, mitochondrial dysfunction and mitochondrial unfolded protein response in the liver of dairy cows.
Chrysin alleviates DNA damage to improve disturbed immune homeostasis and pro-angiogenic environment in laser-induced choroidal neovascularization.
HNRNPA2B1 and HNRNPR stabilize ASCL1 in an m6A-dependent manner to promote neuroblastoma progression.
C/EBPα aggravates renal fibrosis in CKD through the NOX4-ROS-apoptosis pathway in tubular epithelial cells.
Dual action of macrophage miR-204 confines cyclosporine A-induced atherosclerosis.
Subtle structural alteration in indisulam switches the molecular mechanisms for the inhibitory effect on the migration of gastric cancer cells.
Identification of SLC2A1 as a predictive biomarker for survival and response to immunotherapy in lung squamous cell carcinoma.
Rare coding variants in NOX4 link high ROS levels to psoriatic arthritis mutilans.
mGluR7 allosteric modulator AMN082 corrects protein synthesis and pathological phenotypes in FXS.
Selenomethionine alleviates chronic heat stress-induced breast muscle injury and poor meat quality in broilers via relieving mitochondrial dysfunction and endoplasmic reticulum stress.
Benvitimod Inhibits IL-4- and IL-13-Induced Tight Junction Impairment by Activating AHR/ARNT Pathway and Inhibiting STAT6 Phosphorylation in Human Keratinocytes.
Proapoptotic effect of WS-299 induced by NOXA accumulation and NRF2-counterbalanced oxidative stress damage through targeting RBX1-UBE2M interaction in gastric cancers.
Proteomic analysis of adult T-cell leukemia/lymphoma: A biomarker identification strategy based on preparation and in-solution digestion methods of total proteins.
LuQi formula attenuates Cardiomyocyte ferroptosis via activating Nrf2/GPX4 signaling axis in heart failure.
Therapeutic potential of SHCBP1 inhibitor AZD5582 in pancreatic cancer treatment.
MBIP promotes ESCC metastasis by activating MAPK pathway.
Decreased TET2/5-hmC reduces the integrity of the epidermal barrier via epigenetic dysregulation of filaggrin in psoriatic lesions.
Identification of PRDX5 as A Target for The Treatment of Castration-Resistant Prostate Cancer.
Opsin-Free Activation of Bmp Receptors by a Femtosecond Laser.
Pirin Inhibits FAS-Mediated Apoptosis to Support Colorectal Cancer Survival.
Effects of Ban Lian Zi Jin San on intestinal inflammation and barrier function of heat-stressed broilers.
RRM2 promotes the proliferation of chicken myoblasts, inhibits their differentiation and muscle regeneration.
Antagonizing roles of SHP1 in the pathogenesis of Helicobacter pylori infection.
Flavokawain C inhibits proliferation and migration of liver cancer cells through FAK/PI3K/AKT signaling pathway.
Unveiling the Impact of ApoF Deficiency on Liver and Lipid Metabolism: Insights from Transcriptome-Wide m6A Methylome Analysis in Mice.
CD146(+)CAFs promote progression of endometrial cancer by inducing angiogenesis and vasculogenic mimicry via IL-10/JAK1/STAT3 pathway.
TMEM160 promotes tumor immune evasion and radiotherapy resistance via PD-L1 binding in colorectal cancer.
Macrophage-derived exosomal HMGB3 regulates silica-induced pulmonary inflammation by promoting M1 macrophage polarization and recruitment.
Inhibition of SAT1 alleviates chondrocyte inflammation and ferroptosis by repressing ALOX15 expression and activating the Nrf2 pathway.
An oncolytic vaccinia virus encoding hyaluronidase reshapes the extracellular matrix to enhance cancer chemotherapy and immunotherapy.
ST3 beta-galactoside alpha-2,3-sialyltransferase 1 (ST3Gal1) synthesis of Siglec ligands mediates anti-tumour immunity in prostate cancer.
Tetramethylpyrazine alleviates hypoxia-induced proliferation, migration, and inflammatory response of fibroblast-like synoviocytes via inhibiting the HIF-1α- circCDC42BPB pathway.
The RNA m(6)A reader IGF2BP3 regulates NFAT1/IRF1 axis-mediated anti-tumor activity in gastric cancer.
Cell-state dependent regulation of PPAR (γ) signaling by ZBTB9 in adipocytes.
Potential Impact of Hypoxic Astrocytes on the Aggravation of Depressive Symptoms in Parkinson's Disease.
T-2 toxin induces mitochondrial dysfunction in chondrocytes via the p53-cyclophilin D pathway.
Parallel control of cold-triggered adipocyte thermogenesis by UCP1 and CKB.
Spermidine treatment: induction of autophagy but also apoptosis?
Secretome from Magnetically Stimulated Muscle Exhibits Anticancer Potency: Novel Preconditioning Methodology Highlighting HTRA1 Action.
Pooled CRISPR Screening Identifies P-Bodies as Repressors of Cancer Epithelial-Mesenchymal Transition.
Caspase-11/GSDMD contributes to the progression of hyperuricemic nephropathy by promoting NETs formation.
SARS-CoV-2 NSP2 as a Potential Delivery Vehicle for Proteins.
Function and Mechanism of Antiviral Wasp Venom Peptide Protopolybia-MP III and Its Derivatives against HSV-1.
NRF2 activation ameliorates blood-brain barrier injury after cerebral ischemic stroke by regulating ferroptosis and inflammation.
NR4A1 depletion inhibits colorectal cancer progression by promoting necroptosis via the RIG-I-like receptor pathway.
Hinokitiol Inhibits Breast Cancer Cells In Vitro Stemness-Progression and Self-Renewal with Apoptosis and Autophagy Modulation via the CD44/Nanog/SOX2/Oct4 Pathway.
FXR Agonism with Bile Acid Mimetic Reduces Pre-Clinical Triple-Negative Breast Cancer Burden.
SIRT3 alleviates high glucose-induced chondrocyte injury through the promotion of autophagy and suppression of apoptosis in osteoarthritis progression.
Zhuang-Gu-Fang intervenes vasculogenic and osteogenic coupling in GK rats through Notch1/Noggin/VEGF pathway.
Novel biomarkers related to oxidative stress and immunity in chronic kidney disease.
Comprehensive analyses of m1A regulator-mediated modification patterns determining prognosis in lower-grade glioma (running title: m1A in LGG).
Long non-coding RNA LINC01554 overexpression suppresses viability, migration, and invasion of liver cancer cells through regulating miR-148b-3p/EIF4E3.
Dynamics of N6-methyladenosine modification during Alzheimer's disease development.
Extracellular vesicles derived from human foreskin cells (hFS-Exo) accelerate cell migration and angiogenesis through MAPK pathway: an in vitro study.
Integrative analysis of metabolism subtypes and identification of prognostic metabolism-related genes for glioblastoma.
RBP7 functions as a tumor suppressor in HR + breast cancer by inhibiting the AKT/SREBP1 pathway and reducing fatty acid.
Adiponectin Inhibits the Progression of Obesity-Associated Papillary Thyroid Carcinoma Through Autophagy.
Hypermethylation of Bmp2 and Fgfr2 Promoter Regions in Bone Marrow Mesenchymal Stem Cells Leads to Bone Loss in Prematurely Aged Mice.
The nuclear import receptor Kapβ2 modifies neurotoxicity mediated by poly(GR) in C9orf72-linked ALS/FTD.
Propofol improves survival in a murine model of sepsis via inhibiting Rab5a-mediated intracellular trafficking of TLR4.
Urocortin-1 promotes colorectal cancer cell migration and proliferation and inhibits apoptosis via inhibition of the p53 signaling pathway.
Fisetin Alleviates Inflammation and Oxidative Stress in Deep Vein Thrombosis via MAPK and NRF2 Signaling Pathway.
Interleukin-2 enhancer binding factor 2 negatively regulates the replication of duck hepatitis A virus type 1 by disrupting the RNA-dependent RNA polymerase activity of 3D polymerase.
DDX3 regulates cancer immune surveillance via 3' UTR-mediated cell-surface expression of PD-L1.
Enhancer-promoter activation by the Kaposi sarcoma-associated herpesvirus episome maintenance protein LANA.
The Effect of Salvianolic Acid A on Tumor-Associated Macrophage Polarization and Its Mechanisms in the Tumor Microenvironment of Triple-Negative Breast Cancer.
A decrease in integrin α5β1/FAK is associated with increased apoptosis of aortic smooth muscle cells in acute type a aortic dissection.
miR-101-3p-mediated role of PDZK1 in hepatocellular carcinoma progression and the underlying PI3K/Akt signaling mechanism.
Low-intensity pulsed ultrasound reduces alveolar bone resorption during orthodontic treatment via Lamin A/C-Yes-associated protein axis in stem cells.
Piperine promotes PI3K/AKT/mTOR-mediated gut-brain autophagy to degrade α-Synuclein in Parkinson's disease rats.
Dendrobium nobile Lindl. alkaloid decreases Tau hyperphosphorylation via regulating PI3K/Akt/GSK-3β pathway in vitro and in vivo.
Diagnostic value of serum COMP and ADAMTS7 for intervertebral disc degeneration.
RNA splicing regulator EIF3D regulates the tumor microenvironment through immunogene-related alternative splicing in head and neck squamous cell carcinoma.
Loss of TMEM106B exacerbates Tau pathology and neurodegeneration in PS19 mice.
Clostridium butyricum inhibits the inflammation in children with primary nephrotic syndrome by regulating Th17/Tregs balance via gut-kidney axis.
AURKA emerges as a vulnerable target for KEAP1-deficient non-small cell lung cancer by activation of asparagine synthesis.
Lentiviral mediated delivery of CRISPR/Cas9 reduces intraocular pressure in a mouse model of myocilin glaucoma.
FBXO22 promotes glioblastoma malignant progression by mediating VHL ubiquitination and degradation.
CDKL1 potentiates the antitumor efficacy of radioimmunotherapy by binding to transcription factor YBX1 and blocking PD-L1 expression in lung cancer.
Human CCDC51 and yeast Mdm33 are functionally conserved mitochondrial inner membrane proteins that demarcate a subset of organelle fission events.
EIF2Ss, a Novel c-Myc-Correlated Gene Family, is Associated with Poor Prognosis and Immune Infiltration in Pancreatic Adenocarcinoma.
APOC1 is a prognostic biomarker associated with M2 macrophages in ovarian cancer.
The EIF3H-HAX1 axis increases RAF-MEK-ERK signaling activity to promote colorectal cancer progression.
YTHDF1 Promotes Proliferation and Inhibits Apoptosis of Gastric Cancer Cells via Upregulating TCF7 mRNA Translation.
Comprehensive analysis of scRNA-seq and bulk RNA-seq reveal the characteristics of disulfidptosis and a prognostic signature in BLCA.
The E3 ligase TRIM7 suppresses the tumorigenesis of gastric cancer by targeting SLC7A11.
Loss of FoxO1 activates an alternate mechanism of mitochondrial quality control for healthy adipose browning.
Electroacupuncture improves cognitive function in a rat model of mild traumatic brain injury by regulating the SIRT-1/PGC-1α/mitochondrial pathway.
African swine fever virus pH240R enhances viral replication via inhibition of the type I IFN signaling pathway.
NS1-mediated enhancement of MVC transcription and replication promoted by KAT5/H4K12ac.
An alpha-herpesvirus employs host HEXIM1 to promote viral transcription.
Activation of hepatic adenosine A1 receptor ameliorates MASH via inhibiting SREBPs maturation.
Identification of host protein ENO1 (alpha-enolase) interacting with Cryptosporidium parvum sporozoite surface protein, Cpgp40.
RBBP6 maintains glioblastoma stem cells through CPSF3-dependent alternative polyadenylation.
Multiplexed DNA-PAINT Imaging of the Heterogeneity of Late Endosome/Lysosome Protein Composition.
PDCL3 is a prognostic biomarker associated with immune infiltration in hepatocellular carcinoma.
Deubiquitinase PSMD7 facilitates pancreatic cancer progression through activating Nocth1 pathway via modifying SOX2 degradation.
Palmatine alleviates cardiac fibrosis by inhibiting fibroblast activation through the STAT3 pathway.
Cardiac injury activates STING signaling via upregulating SIRT6 in macrophages after myocardial infarction.
Mapping the substrate landscape of protein phosphatase 2A catalytic subunit PPP2CA.
TET2 regulation of alcoholic fatty liver via Srebp1 mRNA in paraspeckles.
Glioblastoma stem cell-derived exosomal miR-374b-3p promotes tumor angiogenesis and progression through inducing M2 macrophages polarization.
DUB3 is a MAGEA3 deubiquitinase and a potential therapeutic target in hepatocellular carcinoma.
Microglia-endothelial cross-talk regulates diabetes-induced retinal vascular dysfunction through remodeling inflammatory microenvironment.
YAP-mediated GPER signaling impedes proliferation and survival of prostate epithelium in benign prostatic hyperplasia.
Basic-helix-loop-helix family member e41 suppresses osteoclastogenesis and abnormal bone resorption disease via NFATc1.
Discovery of novel osthole derivatives exerting anti-inflammatory effect on DSS-induced ulcerative colitis and LPS-induced acute lung injury in mice.
Identification of a ferritinophagy inducer via sinomenine modification for the treatment of colorectal cancer.
Pitavastatin induces autophagy-dependent ferroptosis in MDA-MB-231 cells via the mevalonate pathway.
Cyclin-dependent kinase inhibitor 1A inhibits pyroptosis to enhance human lung adenocarcinoma cell radioresistance by promoting DNA repair.
Modulation of GPER1 alleviates early brain injury via inhibition of A1 reactive astrocytes activation after intracerebral hemorrhage in mice.
PEBP4 deficiency aggravates LPS-induced acute lung injury and alveolar fluid clearance impairment via modulating PI3K/AKT signaling pathway.
Characterization of a novel heterozygous frameshift variant in NDP gene that causes familial exudative vitreoretinopathy in female patients.
NSP6 inhibits the production of ACE2-containing exosomes to promote SARS-CoV-2 infectivity.
GALNT2 targeted by miR-139-5p promotes proliferation of clear cell renal cell carcinoma via inhibition of LATS2 activation.
Interferon-γ in the tumor microenvironment promotes the expression of B7H4 in colorectal cancer cells, thereby inhibiting cytotoxic T cells.
Investigating the therapeutic effects and mechanisms of Carthamus tinctorius L.-derived nanovesicles in atherosclerosis treatment.
Neutrophil Nanodecoys Inhibit Tumor Metastasis by Blocking the Interaction between Tumor Cells and Neutrophils.
Single-cell RNA-seq reveals keratinocyte and fibroblast heterogeneity and their crosstalk via epithelial-mesenchymal transition in psoriasis.
Linker Histone H1.4 Inhibits the Growth, Migration and EMT Process of Non-Small Cell Lung Cancer by Regulating ERK1/2 Expression.
PUF partner interactions at a conserved interface shape the RNA-binding landscape and cell fate in Caenorhabditis elegans.
FA2H controls cool temperature sensing through modifying membrane sphingolipids in Drosophila.
Parathyroid hormone-related protein as a potential prostate cancer biomarker: Promoting prostate cancer progression through upregulation of c-Met expression.
Mefloquine enhances the efficacy of anti-PD-1 immunotherapy via IFN-γ-STAT1-IRF1-LPCAT3-induced ferroptosis in tumors.
Cluster of Differentiation-44-Targeting Prussian Blue Nanoparticles Onloaded with Colchicine for Atherosclerotic Plaque Regression in a Mice Model.
Endothelium-targeted Ddx24 conditional knockout exacerbates ConA-induced hepatitis in mice due to vascular hyper-permeability.
Scleroglucan protects the intestine from irradiation-induced injury by targeting the IL-17 signaling pathway.
Effect of lipopolysaccharide on TAK1-mediated hepatocyte PANoptosis through Toll-like receptor 4 during acute liver failure.
IL-35 ameliorates lipopolysaccharide-induced endothelial dysfunction by inhibiting endothelial-to-mesenchymal transition.
Clinical and functional characterization of rare compound heterozygous mutations in the SERPINC1 gene causing severe thrombophilia.
KIAA1429 facilitates metastasis via m6A-YTHDC1-dependent RND3 down-regulation in hepatocellular carcinoma cells.
Echinacoside alleviates glucocorticoid induce osteonecrosis of femoral head in rats through PI3K/AKT/FOXO1 pathway.
Structural characterization of an inulin neoseries-type fructan from Ophiopogonis Radix and the therapeutic effect on liver fibrosis in vivo.
The role of DRP1 mediated mitophagy in HT22 cells apoptosis induced by silica nanoparticles.
Expression levels of key immune indicators and immune checkpoints in manganese-exposed rats.
Comprehensive Atlas of Alternative Splicing Reveals NSRP1 Promoting Adipogenesis through CCDC18.
Promoting collateral formation in type 2 diabetes mellitus using ultra-small nanodots with autophagy activation and ROS scavenging.
FTO demethylates regulates cell-cycle progression by controlling CCND1 expression in luteinizing goat granulosa cells.
Down-regulating nuclear factor of activated T cells 1 alleviates cognitive deficits in a mouse model of sepsis-associated encephalopathy, possibly by stimulating hippocampal neurogenesis.
GLA Mutations Suppress Autophagy and Stimulate Lysosome Generation in Fabry Disease.
TRIM28-Mediated Excessive Oxidative Stress Induces Cellular Senescence in Granulosa Cells and Contributes to Premature Ovarian Insufficiency In Vitro and In Vivo.
Molecular characterization of the ER stress-inducible factor CRELD2.
The α-1 Adrenergic Receptor Antagonist Doxazosin Attenuates Liver Fibrosis by Alleviating Sinusoidal Capillarization and Liver Angiogenesis.
Inhibition of HDAC6 with CAY10603 alleviates acute and chronic kidney injury by suppressing the ATF6 branch of UPR.
Linc00673-V3 positively regulates autophagy by promoting Smad3-mediated LC3B transcription in NSCLC.
Apigetrin alleviates intervertebral disk degeneration by regulating nucleus pulposus cell autophagy.
Dietary Flavonoid Quercetin Supplement Promotes Antiviral Innate Responses Against Vesicular Stomatitis Virus Infection by Reshaping the Bacteriome and Host Metabolome in Mice.
CircUTRN24/miR-483-3p/IGF-1 Regulates Autophagy Mediated Liver Fibrosis in Biliary Atresia.
Long non‑coding RNA lung cancer‑associated transcript 1 regulates ferroptosis via microRNA‑34a‑5p‑mediated GTP cyclohydrolase 1 downregulation in lung cancer cells.
ROS-dependent S-palmitoylation activates cleaved and intact gasdermin D.
The RNA-binding protein sorbin and SH3 domain-containing 2 are transcriptionally regulated by specificity protein 1 and function as tumor suppressors in bladder cancer by stabilizing tissue factor pathway inhibitor.
BATF promotes extramedullary infiltration through TGF-β1/Smad/MMPs axis in acute myeloid leukemia.
Effect of CHRDL1 on angiogenesis and metastasis of colorectal cancer cells via TGF-β/VEGF pathway.
Linc00239 Promotes Colorectal Cancer Development via MicroRNA-182-5p/Metadherin Axis.
Colorectal cancer cells with stably expressed SIRT3 demonstrate proliferating retardation by Wnt/β-catenin cascade inactivation.
Cysteine and glycine-rich protein 2 is crucial for maintaining the malignant phenotypes of gliomas through its action on Notch signalling cascade.
IL-22 promotes occludin expression by activating autophagy and treats ulcerative colitis.
ITGB2-ICAM1 axis promotes liver metastasis in BAP1-mutated uveal melanoma with retained hypoxia and ECM signatures.
CSGALNACT2 restricts ovarian cancer migration and invasion by modulating MAPK/ERK pathway through DUSP1.
Stiffened tumor microenvironment enhances perineural invasion in breast cancer via integrin signaling.
TRPV1 inhibition suppresses non-small cell lung cancer progression by inhibiting tumour growth and enhancing the immune response.
PHPB ameliorates memory deficits and reduces oxidative injury in Alzheimer's disease mouse model by activating Nrf2 signaling pathway.
Ubiquitin-specific protease 54 regulates GLUT1-mediated aerobic glycolysis to inhibit lung adenocarcinoma progression by modifying p53 degradation.
Electroacupuncture attenuates cerebral ischemia/reperfusion injury by regulating oxidative stress, neuronal death and neuroinflammation via stimulation of PPAR-γ.
Cold atmospheric plasma can effectively disinfect SARS-CoV-2 in the wastewater.
Licochalcone A alleviates ferroptosis in doxorubicin-induced cardiotoxicity via the PI3K/AKT/MDM2/p53 pathway.
Preventive effects of Ramelteon on bleomycin-induced pulmonary fibrosis in mice.
Down-regulation of O-GlcNAcylation alleviates insulin signaling pathway impairment following arsenic exposure via suppressing the AMPK/mTOR-autophagy pathway.
Arsenic exposure induced renal fibrosis via regulation of mitochondrial dynamics and the NLRP3-TGF-β1/SMAD signaling pathway.
Vaccine Targeting Alpha 1D-Adrenergic Receptor Improved Metabolic Syndrome in Mice.
LAMC1 attenuates neuronal apoptosis via FAK/PI3K/AKT signaling pathway after subarachnoid hemorrhage.
BMSC-Exosomes attenuate ALP dysfunction by restoring lysosomal function via the mTOR/TFEB Axis to reduce cerebral ischemia-reperfusion injury.
Bioinspired engineering ADSC nanovesicles thermosensitive hydrogel enhance autophagy of dermal papilla cells for androgenetic alopecia treatment.
Myricanol attenuates sepsis-induced inflammatory responses by nuclear factor erythroid 2-related factor 2 signaling and nuclear factor kappa B/mitogen-activated protein kinase pathway via upregulating Sirtuin 1.
Heparanase interacting BCLAF1 to promote the development and drug resistance of ICC through the PERK/eIF2α pathway.
cGAS suppresses hepatocellular carcinoma independent of its cGAMP synthase activity.
An ATPase-Mimicking MXene nanozyme pharmacologically breaks the ironclad defense system for ferroptosis cancer therapy.
Transient receptor potential mucolipin 1 circumvents oxidative stress in primary human melanocytes.
LUC7L3 is a downstream factor of SRSF1 and prevents genomic instability.
Identification critical host factors for Japanese encephalitis virus replication via CRISPR screening of human sgRNA library.
Staphylococcus aureus promotes its intracellular survival by inhibiting Rab11-Rab11FIP4-mediated vesicle trafficking.
A novel mitochondrial unfolded protein response-related risk signature to predict prognosis, immunotherapy and sorafenib sensitivity in hepatocellular carcinoma.
Circ_0098823 binding with IGF2BP3 regulates DNM1L stability to promote metastasis of hepatocellular carcinoma via mitochondrial fission.
The total xanthones extracted from Gentianella acuta alleviates HFpEF by activating the IRE1α/Xbp1s pathway.
Mechanistic of AMPK/ACC2 regulating myoblast differentiation by fatty acid oxidation of goat.
YTHDF1 regulates immune cell infiltration in gastric cancer via interaction with p53.
Mammalian IRE1α dynamically and functionally coalesces with stress granules.
Calmodulin 2 expression is associated with poor prognosis in breast cancer.
The SGLT2 inhibitor empagliflozin inhibits skeletal muscle fibrosis in naturally aging male mice through the AMPKα/MMP9/TGF-β1/Smad pathway.
Exosomal lncRNA-MIAT promotes neovascularization via the miR-133a-3p/MMP-X1 axis in diabetic retinopathy.
Amyloid precursor protein induces reactive astrogliosis.
LncRNA HOTAIR promotes the migration and invasion of cervical cancer through DNMT3B/LATS1/ YAP1 pS127 axis.
ZNF263 cooperates with ZNF31 to promote the drug resistance and EMT of pancreatic cancer through transactivating RNF126.
Vasorin as an actor of bone turnover?
Overexpression of KAT8 induces a failure in early embryonic development in mice.
Hydrogen alleviates impaired lung epithelial barrier in acute respiratory distress syndrome via inhibiting Drp1-mediated mitochondrial fission through the Trx1 pathway.
Bispecific Nanobody-Aptamer Conjugates for Enhanced Cancer Therapy in Solid Tumors.
RBM3 enhances the stability of MEF2C mRNA and modulates blood-brain barrier permeability in AD microenvironment.
CILP2 promotes hypertrophic scar through Snail acetylation by interaction with ACLY.
Urotensin II receptor deficiency ameliorates ligation-induced carotid intimal hyperplasia partially through the RhoA-YAP1 pathway.
Armed with IL-2 based fusion protein improves CAR-T cell fitness and efficacy against solid tumors.
OTUD1 enhances gastric cancer aggressiveness by deubiquitinating EBV-encoded protein BALF1 to stabilize the apoptosis inhibitor Bcl-2.
The antidepressant effects of protein arginine methyltransferase 2 involve neuroinflammation.
Alpha-tocopherol inhibits ferroptosis and promotes neural function recovery in rats with spinal cord injury via downregulating Alox15.
Therapeutic antibody engineering for efficient targeted degradation of membrane proteins in lysosomes.
Kokusaginine attenuates renal fibrosis by inhibiting the PI3K/AKT signaling pathway.
Prednisone combined with Dihydroartemisinin attenuates systemic lupus erythematosus by regulating M1/M2 balance through the MAPK signaling pathway.
High glucose promotes atherosclerosis by regulating miRNA let7d-5p level.
SLC34A2 promotes cell proliferation by activating STX17-mediated autophagy in esophageal squamous cell carcinoma.
Rapid identifying of COX-2 inhibitors from turmeric (Curcuma longa) by bioaffinity ultrafiltration coupled with UPLC-Q Exactive-Orbitrap-MS and zebrafish-based in vivo validation.
Dual inhibition of oxidative phosphorylation and glycolysis to enhance cancer therapy.
Gastrodin regulates the TLR4/TRAF6/NF-κB pathway to reduce neuroinflammation and microglial activation in an AD model.
Combining cisplatin with Pinellia pedatisecta Schott lipid-soluble extract induces tumor immunogenic cell death in cervical cancer.
Silibinin is a suppressor of the metastasis-promoting transcription factor ID3.
Astragalus polysaccharides attenuate chemotherapy-induced immune injury by modulating gut microbiota and polyunsaturated fatty acid metabolism.
Baicalein improves the symptoms of polycystic ovary syndrome by mitigating oxidative stress and ferroptosis in the ovary and gravid placenta.
Exploring Ca(2+) Dynamics in Myelinating Oligodendrocytes through rAAV-Mediated jGCaMP8s Expression in Developing Spinal Cord Organ Cultures.
N(6)-Methyladenosine-Modified KREMEN2 Promotes Tumorigenesis and Malignant Progression of High-Grade Serous Ovarian Cancer.
Computer-aided discovery of novel aryl hydrocarbon receptor ligands to regulate CYP1A1 expression in inflammatory macrophages.
Effects of lighted incubation and foraging enrichment during rearing on individual fear behavior, corticosterone, and neuroplasticity in laying hen pullets.
Pan-Cancer Proteomics Analysis Reveals Wiskott-Aldrich Syndrome Protein as a Potential Regulator of Programmed Death-Ligand 1.
Mechanistic insights into super-enhancer-related genes as prognostic signatures in colon cancer.
linc01152 Regulates Cell Viability, Cell Migration and Cell Invasion of Breast Cancer via Regulating miR-320a and MTDH.
Depletion of cap-binding protein eIF4E dysregulates amino acid metabolic gene expression.
Involvement of necroptotic cell death in macrophages in progression of bleomycin and LPS-induced acute exacerbation of idiopathic pulmonary fibrosis.
N6022 attenuates cerebral ischemia/reperfusion injury-induced microglia ferroptosis by promoting Nrf2 nuclear translocation and inhibiting the GSNOR/GSTP1 axis.
Resveratrol attenuates cyclosporin A-induced upregulation of the thromboxane A(2) receptor and hypertension via the AMPK/SIRT1 and MAPK/NF-κB pathways in the rat mesenteric artery.
Identification of hub genes and potential therapeutic mechanisms related to HPV positive head and neck squamous carcinoma based on full transcriptomic detection and ceRNA network construction.
A Recql5 mutant facilitates complex CRISPR/Cas9-mediated chromosomal engineering in mouse zygotes.
Microglial lipid droplet accumulation in tauopathy brain is regulated by neuronal AMPK.
lncRNA JPX Promotes Tumor Progression by Interacting with and Destabilizing YTHDF2 in Cutaneous Melanoma.
2'-Hydroxycinnamaldehyde Alleviates Intestinal Inflammation by Attenuating Intestinal Mucosal Barrier Damage Via Directly Inhibiting STAT3.
Neuroinflammation and Lysosomal Abnormalities Characterise the Essential Role for Oxidation Resistance 1 in the Developing and Adult Cerebellum.
FTO elicits tumor neovascularization in cancer-associated fibroblasts through eliminating m(6)A modifications of multiple pro-angiogenic factors.
NFIC mediates m6A mRNA methylation to orchestrate transcriptional and post-transcriptional regulation to represses malignant phenotype of non-small cell lung cancer cells.
Circular RNA HSDL2 promotes breast cancer progression via miR-7978 ZNF704 axis and regulating hippo signaling pathway.
TRIM26 deficiency enhancing liver regeneration through macrophage polarization and β-catenin pathway activation.
Mammalian orthoreovirus capsid protein σ3 antagonizes RLR-mediated antiviral responses by degrading MAVS.
Blockage of L2HGDH-mediated S-2HG catabolism orchestrates macrophage polarization to elicit antitumor immunity.
Circular RNA circLIFR suppresses papillary thyroid cancer progression by modulating the miR-429/TIMP2 axis.
Small Molecule-Inducible and Photoactivatable Cellular RNA N1-Methyladenosine Editing.
Acetyl-NPKY of integrin-β1 binds KINDLIN2 to control endothelial cell proliferation and junctional integrity.
NIR-responsive CN-Pt-GEM hydrogel induces necroptosis and immunotherapeutic responses prevent postoperative recurrence and wound infection in lung carcinoma.
Ophiobolin A Covalently Targets Mitochondrial Complex IV Leading to Metabolic Collapse in Cancer Cells.
The Role of TPM3 in Protecting Cardiomyocyte from Hypoxia-Induced Injury via Cytoskeleton Stabilization.
Circ_0004851 regulates the molecular mechanism of miR-296-3p/FGF11 in the influence of high iodine on PTC.
Neutrophil extracellular traps induce pyroptosis of pulmonary microvascular endothelial cells by activating the NLRP3 inflammasome.
RANKL/RANK signaling recruits Tregs via the CCL20-CCR6 pathway and promotes stemness and metastasis in colorectal cancer.
Network pharmacology and biochemical experiments reveal the antiapoptotic mechanism of huperzine A for treating diabetic retinopathy.
CSTF3 contributes to platinum resistance in ovarian cancer through alternative polyadenylation of lncRNA NEAT1 and generating the short isoform NEAT1_1.
Glutamatergic neuronal activity regulates angiogenesis and blood-retinal barrier maturation via Norrin/β-catenin signaling.
Loss of FAM172A gene prompts cell proliferation in liver regeneration.
Stachydrine hydrochloride protects the ischemic heart by ameliorating endoplasmic reticulum stress through a SERCA2a dependent way and maintaining intracellular Ca(2+) homeostasis.
Study on the mechanism of S100A4-mediated cancer oncogenesis in uveal melanoma cells through the integration of bioinformatics and in vitro experiments.
Sodium arsenite induces hepatic stellate cells activation by m(6)A modification of TGF-β1 during liver fibrosis.
Tat-NR2B9c attenuates oxidative stress via inhibition of PSD95-NR2B-nNOS complex after subarachnoid hemorrhage in rats.
CK1δ/ε kinases regulate TDP-43 phosphorylation and are therapeutic targets for ALS-related TDP-43 hyperphosphorylation.
Trim27 aggravates airway inflammation and oxidative stress in asthmatic mice via potentiating the NLRP3 inflammasome.
A novel Senescence-Based prognostic model unveils tumor interactions and drug resistance in colorectal cancer.
Recombinant fibroblast growth factor 4 ameliorates axonal regeneration and functional recovery in acute spinal cord injury through altering microglia/macrophage phenotype.
Cardiac Fibroblasts Enhance MMP2 Activity to Suppress Gap Junction Function in Cardiomyocytes.
Absent in Melanoma 2 Mediates Inflammasome Signaling Activation against Clostridium perfringens Infection.
Prostate Cancer-Specific Lysine 53 Acetylation of Cytochrome c Drives Metabolic Reprogramming and Protects from Apoptosis in Intact Cells.
Inhibition and reversal of a TGF-β1 induced myofibroblast phenotype by adipose tissue-derived paracrine factors.
Therapeutic potential of CB(1)R activation by Qingyangshen glycoside M1 for seizure relief.
Xanthoceras sorbifolium leaves alleviate hyperuricemic nephropathy by inhibiting the PI3K/AKT signaling pathway to regulate uric acid transport.
Human gastric cancer progression and stabilization of ATG2B through RNF5 binding facilitated by autophagy-associated CircDHX8.
Terpinen-4-ol Improves Lipopolysaccharide-Induced Macrophage Inflammation by Regulating Glutamine Metabolism.
Attenuating bone loss in osteoporosis: the potential of corylin (CL) as a therapeutic agent.
d-mannose targets PD-1 to lysosomal degradation and enhances T cell-mediated anti-tumor immunity.
FBXO43 promotes cell cycle progression in cancer cells through stabilizing SKP2.
Forsythiaside A attenuates lipopolysaccharide-induced mouse mastitis by activating autophagy and regulating gut microbiota and metabolism.
Tobacco toxins trigger bone marrow mesenchymal stem cells aging by inhibiting mitophagy.
Overexpression of FHL1 suppresses papillary thyroid cancer proliferation and progression via inhibiting Wnt/β-catenin pathway.
CK2 activity is crucial for proper glucagon expression.
HHLA2 promotes hepatoma cell proliferation, migration, and invasion via SPP1/PI3K/AKT signaling pathway.
Hypomethylation-associated LINC00987 downregulation induced lung adenocarcinoma progression by inhibiting the phosphorylation-mediated degradation of SND1.
Loss of PTPRS elicits potent metastatic capability and resistance to temozolomide in glioblastoma.
Selenium nanoparticles decorated with polysaccharides from Sargassum fusiforme protects against 6-OHDA-induced neurotoxicity in PC12 cells and rat model of Parkinson's disease.
MSRB2 Ameliorates H(2)O(2)-induced Chondrocyte Oxidative Stress and Suppresses Apoptosis in Osteoarthritis.
Parkin deficiency promotes liver cancer metastasis by TMEFF1 transcription activation via TGF-β/Smad2/3 pathway.
Vagus nerve stimulation as a promising neuroprotection for ischemic stroke via α7nAchR-dependent inactivation of microglial NLRP3 inflammasome.
HMGB2 is a biomarker associated with poor prognosis promoting radioresistance in glioma by targeting base excision repair pathway.
Physiologically based pharmacokinetic modeling for confirming the role of CYP3A1/2 and P-glycoprotein in detoxification mechanism between glycyrrhizic acid and aconitine in rats.
PM(2.5) exposure inhibits osteoblast differentiation by increasing the ubiquitination and degradation of Smad4.
Asiatic acid inhibits osteosarcoma cell migration and invasion via the AKT/Sp1/MMP1 axis.
STAU1 exhibits a dual function by promoting amyloidogenesis and tau phosphorylation in cultured cells.
Influence of METTL3 knockdown on PDLSC osteogenesis in E. coli LPS-induced inflammation.
Estrogen inhibits TGF‑β1‑stimulated cardiac fibroblast differentiation and collagen synthesis by promoting Cdc42.
GPX7 reduces chondrocyte inflammation and extracellular matrix degradation triggered by IL‑1β, via a mechanism mediated by ferroptosis.
Mefunidone ameliorates acute liver failure in mice by inhibiting MKK4-JNK pathway.
Chronic Fluoride Exposure Induces Ovarian Dysfunction and Potential Association with Premature Ovarian Failure in Female Rats.
Knockdown of LncRNA Lcn2-204 alleviates sepsis-induced myocardial injury by regulation of iron overload and ferroptosis.
Multiomics Analysis Reveals Leucine Deprivation Promotes Bile Acid Synthesis by Upregulating Hepatic CYP7A1 and Intestinal Turicibacter sanguinis in Mice.
A novel selenium nanocomposite modified by AANL inhibits tumor growth by upregulating CLK2 in lung cancer.
Protective effects of Wenqingyin on sepsis-induced acute lung injury through regulation of the receptor for advanced glycation end products pathway.
Antidiabetic action of the Chinese formula Shouhuitongbian and the underlying mechanism associated with alteration of gut microbiota.
Effects of xylo-oligosaccharide on gut microbiota, brain protein expression, and lipid profile induced by high-fat diet.
Effects of spinal cord injury associated exosomes delivered tRF-41 on the progression of spinal cord injury progression.
CYP3A5 unexpectedly regulates glucose metabolism through the AKT-TXNIP-GLUT1 axis in pancreatic cancer.
Estrogen promotes gonadotropin-releasing hormone expression by regulating tachykinin 3 and prodynorphin systems in chicken.
Long non-coding RNA KB-1460A1.5 promotes ferroptosis by inhibiting mTOR/SREBP-1/SCD1-mediated polyunsaturated fatty acid desaturation in glioma.
A novel framework for functional annotation of variants of uncertain significance in ID/ASD risk gene CC2D1A.
Oridonin promotes RSL3-induced ferroptosis in breast cancer cells by regulating the oxidative stress signaling pathway JNK/Nrf2/HO-1.
MiR-29a efficiently suppresses the generation of reactive oxygen species and α-synuclein in a cellular model of Parkinson's disease by potentially targeting GSK-3β.
SUMOylation modification of FTO facilitates oxidative damage response of arsenic by IGF2BP3 in an m6A-dependent manner.
Podophyllotoxin via SIRT1/PPAR /NF-κB axis induced cardiac injury in rats based on the toxicological evidence chain (TEC) concept.
Single-Cell and Spatial Transcriptome Profiling Identifies the Transcription Factor BHLHE40 as a Driver of EMT in Metastatic Colorectal Cancer.
Vasorin Exocytosed from Glioma Cells Facilitates Angiogenesis via VEGFR2/AKT Signaling Pathway.
Fangji Huangqi Decoction alleviates rheumatoid arthritis through regulating HIF-1α mediated the angiogenesis and the balance between autophagy and apoptosis.
Exposure memory and susceptibility to ambient PM(2.5): A perspective from hepatic cholesterol and bile acid metabolism.
4D label-free quantitative proteomic analysis identifies CRABP1 as a novel candidate gene for litter size in rabbits†.
Structural and functional insights into yeast Tbf1 as an atypical telomeric repeat-binding factor.
Bacillus cereus CwpFM induces colonic tissue damage and inflammatory responses through oxidative stress and the NLRP3/NF-κB pathway.
AGPAT3 deficiency impairs adipocyte differentiation and leads to a lean phenotype in mice.
Maternal high fat diet programs spatial learning and central leptin signaling in mouse offspring in a sex-specific manner.
Regulating effect of miR-132-3p on the changes of MAPK pathway in rat brains and SH-SY5Y cells exposed to excessive fluoride by targeting expression of MAPK1.
Fibroblast growth factor 21 inhibits ferroptosis following spinal cord injury by regulating heme oxygenase-1.
SLC7A11 promotes EMT and metastasis in invasive pituitary neuroendocrine tumors by activating the PI3K/AKT signaling pathway.
Analysis of multiple programmed cell death-related prognostic genes and functional validations of necroptosis-associated genes in oesophageal squamous cell carcinoma.
Multi-omics analyses reveal bacteria and catalase associated with keloid disease.
Loss of STARD13 contributes to aggressive phenotype transformation and poor prognosis in papillary thyroid carcinoma.
Arsenic induced neurotoxicity in the brain of ducks: The potential involvement of the gut-brain axis.
Downregulation of Rab23 inhibits hepatocellular carcinoma by repressing SHH signaling pathway.
pH Sensitive Quercetin Nanoparticles Ameliorate DSS-Induced Colitis in Mice by Colon-Specific Delivery.
circPPP2R4 promotes colorectal cancer progression and reduces ROS production through the miR-646/FOXK1 axis.
Na(v)1.7 as a chondrocyte regulator and therapeutic target for osteoarthritis.
L116 Deletion in CSPα Promotes α-Synuclein Aggregation and Neurodegeneration.
Tumor suppressor CLCA1 inhibits angiogenesis via TGFB1/SMAD/VEGF cascade and sensitizes hepatocellular carcinoma cells to Sorafenib.
Comparative analyses of the Smith-Magenis syndrome protein RAI1 in mice and common marmoset monkeys.
Gab2 promotes the growth of colorectal cancer by regulating the M2 polarization of tumor‑associated macrophages.
IL-4/STAT6 axis observed to reverse proliferative defect in SCA3 patient-derived neural progenitor cells.
SYNPO2 promotes the development of BLCA by upregulating the infiltration of resting mast cells and increasing the resistance to immunotherapy.
ATR induces hepatic lipid metabolism disorder in rats by activating IRE1α/XBP1 signaling pathway.
Lymphatic endothelial-like cells promote glioblastoma stem cell growth through cytokine-driven cholesterol metabolism.
Hsa_circ_0001583 fuels bladder cancer metastasis by promoting staphylococcal nuclease and tudor domain containing 1-mediated MicroRNA decay.
SRSF7 is a promising prognostic biomarker in hepatocellular carcinoma and is associated with immune infiltration.
Sirtuin 6 protects against podocyte injury by blocking the renin-angiotensin system by inhibiting the Wnt1/β-catenin pathway.
Nerolidol attenuates airway inflammation and airway remodeling and alters gut microbes in ovalbumin-induced asthmatic mice.
Leukocyte-poor platelet-rich plasma and leukocyte-rich platelet-rich plasma promote myoblast proliferation through the upregulation of cyclin A, cdk1, and cdk2.
Mitofusin2 Ameliorated Endoplasmic Reticulum Stress and Mitochondrial Reactive Oxygen Species Through Maintaining Mitochondria-Associated Endoplasmic Reticulum Membrane Integrity in Cisplatin-Induced Acute Kidney Injury.
Anti-inflammatory activities of several diterpenoids isolated from Hemionitis albofusca.
Non-small cell lung cancer cells with uncommon EGFR exon 19delins variants respond poorly to third-generation EGFR inhibitors.
Hsa_circ_0020134 promotes liver metastasis of colorectal cancer through the miR-183-5p-PFN2-TGF-β/Smad axis.
CYB5R1 is a potential biomarker that correlates with stemness and drug resistance in gastric cancer.
Pro-osteogenic role of interleukin-22 in calcific aortic valve disease.
Uric acid promotes interleukin-17 expression to cause kidney injury.
Advanced glycation end products induce nucleus pulposus cell apoptosis by upregulating TXNIP via inhibiting glycolysis pathway in intervertebral disc degeneration.
MiR-9 promotes G-MDSC recruitment and tumor proliferation by targeting SOCS3 in breast cancer.
MicroRNA-10a-5p-mediated downregulation of GATA6 inhibits tumor progression in ovarian cancer.
Injectable dexamethasone-loaded peptide hydrogel for therapy of radiation-induced ototoxicity by regulating the mTOR signaling pathway.
Exposure of embryos to fenbuconazole causes persistent neurotoxicity in adult zebrafish.
PCB126 impairs human sperm functions by affecting post-translational modifications and mitochondrial functions.
RNA sequencing reveals the transcriptomic landscape and alternative splicing events induced by LGALS1 silencing in non-small cell lung cancer.
IDO-1 impairs antitumor immunity of natural killer cells in triple-negative breast cancer via up-regulation of HLA-G.
EAAT3 impedes oligodendrocyte remyelination in chronic cerebral hypoperfusion-induced white matter injury.
Transcriptomics reveal a molecular signature in the progression of nonalcoholic steatohepatitis and identifies PAI‑1 and MMP‑9 as biomarkers in in vivo and in vitro studies.
Duck Tembusu virus infection activates the MKK3/6-p38 MAPK signaling pathway to promote virus replication.
Ailanthone synergizes with PARP1 inhibitor in tumour growth inhibition through crosstalk of DNA repair pathways in gastric cancer.
Oncostatin M enhances osteoprotegerin synthesis but reduces macrophage colony‑stimulating factor synthesis in bFGF‑stimulated osteoblast‑like cells.
Hematoporphyrin derivative photodynamic therapy induces apoptosis and suppresses the migration of human esophageal squamous cell carcinoma cells by regulating the PI3K/AKT/mTOR signaling pathway.
Ovarian carcinoma immune-related microRNA affects the heterogeneity of the endocrine microenvironment and anti-tumor immune pattern.
CircDYM attenuates microglial apoptosis via CEBPB/ZC3H4 axis in LPS-induced mouse model of depression.
Vasculogenic mimicry-associated novel gene signature predicted prognosis and response to immunotherapy in lung adenocarcinoma.
Bridging integrator 1 fragment accelerates tau aggregation and propagation by enhancing clathrin-mediated endocytosis in mice.
STING modulates iron metabolism to promote liver injury and inflammation in acute immune hepatitis.
Melatonin attenuates sepsis-induced acute kidney injury by promoting mitophagy through SIRT3-mediated TFAM deacetylation.
A proteome-wide screen identifies the calcium binding proteins, S100A8/S100A9, as clinically relevant therapeutic targets in aortic dissection.
Overexpression of Corin Ameliorates Kidney Fibrosis through Inhibition of Wnt/β-Catenin Signaling in Mice.
Pathologic changes in neuronal intranuclear inclusion disease are linked to aberrant FUS interaction under hyperosmotic stress.
Highly efficient identification of nucleocytoplasmic O-glycosylation by the TurboID-based proximity labeling method in living cells.
Photobiomodulation inhibits the expression of chondroitin sulfate proteoglycans after spinal cord injury via the Sox9 pathway.
Ambra1 in exosomes secreted by HK-2 cells damaged by supersaturated oxalate induce mitophagy and autophagy-ferroptosis in normal HK-2 cells to participate in the occurrence of kidney stones.
Dectin1 contributes to hypertensive vascular injury by promoting macrophage infiltration through activating the Syk/NF-κB pathway.
Melatonin inhibits fibroblast cell functions and hypertrophic scar formation by enhancing autophagy through the MT2 receptor-inhibited PI3K/Akt /mTOR signaling.
Lactobacillus species ameliorate membranous nephropathy through inhibiting the aryl hydrocarbon receptor pathway via tryptophan-produced indole metabolites.
AhR-STAT3-HO-1/COX-2 signalling pathway may restrict ferroptosis and improve hMSC accumulation and efficacy in mouse liver.
USP7 reduces the level of nuclear DICER, impairing DNA damage response and promoting cancer progression.
Osteoblast-derived exosomes promote osteogenic differentiation of osteosarcoma cells via URG4/Wnt signaling pathway.
Integrated transcriptomic and proteomic analysis reveals Guizhi-Fuling Wan inhibiting STAT3-EMT in ovarian cancer progression.
Formononetin ameliorates isoproterenol induced cardiac fibrosis through improving mitochondrial dysfunction.
dCas9/CRISPR-based methylation of O-6-methylguanine-DNA methyltransferase enhances chemosensitivity to temozolomide in malignant glioma.
FAM21 interacts with Ku to promote the localization of WASH to DNA double strand break sites.
Helenine blocks NLRP3 activation by disrupting the NEK7-NLRP3 interaction and ameliorates inflammatory diseases.
Reduced estrogen signaling contributes to bone loss and cardiac dysfunction in interleukin-10 knockout mice.
PKD knockdown mitigates Ang II-induced cardiac hypertrophy and ferroptosis via the JNK/P53 signaling pathway.
Identification and functional coordination analysis of gene co-expression networks in different tissues of XBP1 cartilage-specific deficient mice.
Manganese Enhances the Osteogenic Effect of Silicon-Hydroxyapatite Nanowires by Targeting T Lymphocyte Polarization.
Cytoplasmic Escape of Mitochondrial DNA Mediated by Mfn2 Downregulation Promotes Microglial Activation via cGas-Sting Axis in Spinal Cord Injury.
Arf1 GTPase Regulates Golgi-Dependent G2/M Transition and Spindle Organization in Oocyte Meiosis.
Ganoderic acid A slows osteoarthritis progression by attenuating endoplasmic reticulum stress and blocking NF-Κb pathway.
A novel lncRNA LOC105613571 binding with BDNF in pituitary promotes gonadotropin secretion by AKT/ERK-mTOR pathway in sheep associated with prolificacy.
Corydalis saxicolaBunting total alkaloid eliminates Porphyromonas gingivalis strain 33277 internalized into macrophages by inhibition of TLR2.
Irradiated Cell-derived Exosomes Enhance Cell Proliferation and Radioresistance via the MAPK/Erk Pathway.
Macrophage-derived exosomal miRNA-141 triggers endothelial cell pyroptosis by targeting NLRP3 to accelerate sepsis progression.
Regulation of the immune microenvironment by pioglitazone-loaded polylactic glycolic acid nanosphere composite scaffolds to promote vascularization and bone regeneration.
Enhanced Gasdermin-E-mediated Pyroptosis in Alzheimer's Disease.
Upregulation of TTK expression is associated with poor prognosis and immune infiltration in endometrial cancer patients.
Hepcidin deficiency impairs hippocampal neurogenesis and mediates brain atrophy and memory decline in mice.
The role of angiotensin II activation of yes-associated protein/PDZ-binding motif signaling in hypertensive cardiac and vascular remodeling.
Ovatodiolide induces autophagy-mediated cell death through the p62-Keap1-Nrf2 signaling pathway in chronic myeloid leukemia cells.
Excessive Mitochondrial Fission Suppresses Mucosal Repair by Impairing Butyrate Metabolism in Colonocytes.
Proteomic Analysis of the Supernatant from Bone Marrow Mesenchymal Stem Cells under High Glucose Conditions.
Proteomic and Phosphoproteomic Analysis of Right Ventricular Hypertrophy in the Pulmonary Hypertension Rat Model.
ARTC1-mediated VAPB ADP-ribosylation regulates calcium homeostasis.
Caveolin 1 Regulates the Tight Junctions between Sertoli Cells and Promotes the Integrity of Blood-Testis Barrier in Yak via the FAK/ERK Signaling Pathway.
The combination of tetracyclines effectively ameliorates liver fibrosis via inhibition of EphB1/2.
Liriodendrin exerts protective effects against chronic endometritis in rats by modulating gut microbiota composition and the arginine/nitric oxide metabolic pathway.
High-expressed ACAT2 predicted the poor prognosis of platinum-resistant epithelial ovarian cancer.
TET2-mediated tumor cGAS triggers endothelial STING activation to regulate vasculature remodeling and anti-tumor immunity in liver cancer.
KAT8 functions in redox homeostasis and mitochondrial dynamics during mouse oocyte meiosis progression.
Folate supports IL-25-induced tuft cell expansion following enteroviral infections.
Treatment with sodium butyrate induces autophagy resulting in therapeutic benefits for spinocerebellar ataxia type 3.
Targeting FBXO22 enhances radiosensitivity in non-small cell lung cancer by inhibiting the FOXM1/Rad51 axis.
Explore Key Genes and Mechanisms Involved in Colon Cancer Progression Based on Bioinformatics Analysis.
TMT-based proteomics analysis identifies the interventional mechanisms of Qijia Rougan decoction in improving hepatic fibrosis.
Kuijie decoction ameliorates ulcerative colitis by affecting intestinal barrier functions, gut microbiota, metabolic pathways and Treg/Th17 balance in mice.
Mechanism of Sophorae Flavescentis Radix (Kushen) in treating NSCLC: Insights from miRNA-mRNA network analysis.
Diterpenoid WT-29 isolated from Wedelia exerted anti-inflammatory and anti-allergic activities.
Protective effect of Huangqi-Guizhi-Wuwutang against cyclophosphamide-induced spermatogenesis dysfunction in mice by promoting steroid hormone biosynthesis.
Quercetin inhibits mesothelial-mesenchymal transition and alleviates postoperative peritoneal adhesions by blocking the TGF-β1/PI3K/AKT pathway.
Cholinergic signaling of muscarinic receptors directly involves in the neuroprotection of muscone by inducing Ca(2+) antagonism and maintaining mitochondrial function.
Shenqu xiaoshi oral solution enhances digestive function and stabilizes the gastrointestinal microbiota of juvenile rats with infantile anorexia.
Chicken Interferon-Alpha and -Lambda Exhibit Antiviral Effects against Fowl Adenovirus Serotype 4 in Leghorn Male Hepatocellular Cells.
Tumorous IRE1α facilitates CD8(+)T cells-dependent anti-tumor immunity and improves immunotherapy efficacy in melanoma.
The pathogenic role of succinate-SUCNR1: a critical function that induces renal fibrosis via M2 macrophage.
Enhanced meningeal lymphatic drainage ameliorates lipopolysaccharide-induced brain injury in aged mice.
Vitamin D-mediated tsRNA-07804 triggers mitochondrial dysfunction and suppresses non-small cell lung cancer progression by targeting CRKL.
A peptide from the Japanese encephalitis virus failed to induce the production of anti-N-methyl-d-aspartate receptor antibodies via molecular mimicry in mice.
Multifunctional Fe-based coordination polymer nano-bomb modified with β-lapachone and CaO(2) for targeted tumor dual chemodynamic therapy with enhanced ferroptosis and H(2)O(2) self-supply.
Sophocarpine alleviates doxorubicin-induced heart injury by suppressing oxidative stress and apoptosis.
Inhibition of heme oxygenase 1 alleviates thoracic aortic aneurysm via restoration of extracellular matrix.
Schizandrin A attenuates early brain injury following subarachnoid hemorrhage through suppressing neuroinflammation.
FBW7/GSK3β mediated degradation of IGF2BP2 inhibits IGF2BP2-SLC7A5 positive feedback loop and radioresistance in lung cancer.
Circ-phkb promotes cell apoptosis and inflammation in LPS-induced alveolar macrophages via the TLR4/MyD88/NF-kB/CCL2 axis.
Dopamine modification of glycolytic enzymes impairs glycolysis: possible implications for Parkinson's disease.
Sesamin-mediated high expression of BECN2 ameliorates cartilage endplate degeneration by reducing autophagy and inflammation.
UBR5 promotes antiviral immunity by disengaging the transcriptional brake on RIG-I like receptors.
Endoplasmic reticulum stress caused by traumatic injury promotes cardiomyocyte apoptosis through acetylation modification of GRP78.
Melatonin alleviates valproic acid-induced neural tube defects by modulating Src/PI3K/ERK signaling and oxidative stress.
Molecular mechanism of specific DNA sequence recognition by NRF1.
Prognosis and immunotherapy response prediction based on M2 macrophage-related genes in colon cancer.
Irisin mitigates rheumatoid arthritis by suppressing mitochondrial fission via inhibiting YAP-Drp1 signaling pathway.
The improvement of homocysteine-induced myocardial inflammation by vitamin D depends on activation of NFE2L2 mediated MTHFR.
Monotropein induces autophagy through activation of the NRF2/PINK axis, thereby alleviating sepsis-induced colonic injury.
Liensinine alleviates mouse intestinal injury induced by sepsis through inhibition of oxidative stress, inflammation, and cell apoptosis.
Simultaneous inhibition of FAK and ROS1 synergistically repressed triple-negative breast cancer by upregulating p53 signalling.
TonEBP: A Key Transcription Factor in Microglia Following Intracerebral Hemorrhage Induced-Neuroinflammation.
Ganoderma lucidum polysaccharide ameliorates cholesterol gallstone formation by modulating cholesterol and bile acid metabolism in an FXR-dependent manner.
Investigation of Tongxie-Yaofang formula in treating ulcerative colitis based on network pharmacology via regulating MAPK/AKT signaling pathway.
Scinderin promotes glioma cell migration and invasion via remodeling actin cytoskeleton.
LncRNA HOTAIR regulates autophagy and proliferation mechanisms in premature ovarian insufficiency through the miR-148b-3p/ATG14 axis.
Integrin β1-rich extracellular vesicles of kidney recruit Fn1+ macrophages to aggravate ischemia-reperfusion-induced inflammation.
HIF-2α/LINC02609/APOL1-mediated lipid storage promotes endoplasmic reticulum homeostasis and regulates tumor progression in clear-cell renal cell carcinoma.
Stabilization of KPNB1 by deubiquitinase USP7 promotes glioblastoma progression through the YBX1-NLGN3 axis.
NEIL1 drives the initiation of colorectal cancer through transcriptional regulation of COL17A1.
Cyclic increase in the ADAMTS1-L1CAM-EGFR axis promotes the EMT and cervical lymph node metastasis of oral squamous cell carcinoma.
AKT1 phosphorylation of cytoplasmic ME2 induces a metabolic switch to glycolysis for tumorigenesis.
Exogenous carbon monoxide promotes GPX4-dependent ferroptosis through ROS/GSK3β axis in non-small cell lung cancer.
Investigating the therapeutic effects and mechanisms of Roxadustat on peritoneal fibrosis Based on the TGF-β/Smad pathway.
Self-assembled coating with a metal-polyphenolic network for intraocular lens modification to prevent posterior capsule opacification.
YAP represses intestinal inflammation through epigenetic silencing of JMJD3.
DNA polymerase beta connects tumorigenicity with the circadian clock in liver cancer through the epigenetic demethylation of Per1.
LDLR is used as a cell entry receptor by multiple alphaviruses.
Single-Cell Transcriptomic Sequencing Reveals Tissue Architecture and Deciphers Pathological Reprogramming During Retinal Ischemia in Macaca fascicularis.
microRNA-622 upregulates cell cycle process by targeting FOLR2 to promote CRC proliferation.
Development and validation of a disulfidptosis and disulfide metabolism-related risk index for predicting prognosis in lung adenocarcinoma.
SP4 Facilitates Esophageal Squamous Cell Carcinoma Progression by Activating PHF14 Transcription and Wnt/Β-Catenin Signaling.
NET1 is a critical regulator of spindle assembly and actin dynamics in mouse oocytes.
Function and mechanism of GBP1 in the development and progression of cervical cancer.
D-mannose promotes the degradation of IDH2 through upregulation of RNF185 and suppresses breast cancer.
The oncogenic role and regulatory mechanism of PGK1 in human non-small cell lung cancer.
Pharmaceutical targeting of OTUB2 sensitizes tumors to cytotoxic T cells via degradation of PD-L1.
FOXP3(+) regulatory T cell perturbation mediated by the IFNγ-STAT1-IFITM3 feedback loop is essential for anti-tumor immunity.
IL-21-armored B7H3 CAR-iNKT cells exert potent antitumor effects.
Targeted Protein Degradation through Recruitment of the CUL4 Complex Adaptor Protein DDB1.
Two mitochondrial DNA polymorphisms modulate cardiolipin binding and lead to synthetic lethality.
The CUL5 E3 ligase complex negatively regulates central signaling pathways in CD8(+) T cells.
Macrophage-expressed SRA ameliorates alcohol-induced liver injury by suppressing S-glutathionylation of Notch1 via recruiting thioredoxin.
LINC00571 drives tricarboxylic acid cycle metabolism in triple-negative breast cancer through HNRNPK/ILF2/IDH2 axis.
Revealing the mechanism of 755-nm long-pulsed alexandrite laser in inhibiting infantile hemangioma endothelial cells through transcriptome sequencing.
APOE3ch alters microglial response and suppresses Aβ-induced tau seeding and spread.
Metabolic regulation of homologous recombination repair by MRE11 lactylation.
METTL3 drives NSCLC metastasis by enhancing CYP19A1 translation and oestrogen synthesis.
Identification of a basement membrane gene signature for predicting prognosis and estimating the tumor immune microenvironment in prostate cancer.
Long non-coding RNA MEG3 acts as a suppressor in breast cancer by regulating miR-330/CNN1.
Heliox Protects SH-SY5Y Cells from Oxygen-Glucose Deprivation/Reperfusion-Induced Ferroptosis.
MicroRNA-218-5p-Ddx41 axis restrains microglia-mediated neuroinflammation through downregulating type I interferon response in a mouse model of Parkinson's disease.
Lifespan Effects of Muscle-Specific Androgen Receptor Overexpression on Body Composition of Male and Female Rats.
HOOK3 suppresses proliferation and metastasis in gastric cancer via the SP1/VEGFA axis.
Cyanidin-3-O-glucoside and its derivative vitisin A alleviate androgenetic alopecia by exerting anti-androgen effect and inhibiting dermal papilla cell apoptosis.
Amiloride alleviates morphine tolerance by suppressing ASIC3-dependent neuroinflammation in the spinal cord.
Detrimental Role of CXCR3 in α-Naphthylisothiocyanate- and Triptolide-Induced Cholestatic Liver Injury.
Detection of glucose transporter 1 in living cells for assessment of tumor development and therapy using an electrochemical biosensor.
Electroacupuncture ameliorates cognitive impairment in APP/PS1 mouse by modulating TFEB levels to relieve ALP dysfunction.
Remote modulation of WWOX by an intronic variant associated with survival of Chinese gastric cancer patients.
Construction of a Novel Damage-Associated Molecular-Pattern-Related Signature to Assess Lung Adenocarcinoma's Prognosis and Immune Landscape.
MicroRNA-146a-loaded magnesium silicate nanospheres promote bone regeneration in an inflammatory microenvironment.
Nitidine chloride inhibits G2/M phase by regulating the p53/14-3-3 Sigma/CDK1 axis for hepatocellular carcinoma treatment.
ANP32B promotes colorectal cancer cell progression and reduces cell sensitivity to PRAP1 inhibitor through up-regulating HPF1.
ERRα regulates synaptic transmission through reactive oxygen species in hippocampal neurons.
Jianpi Yangxue Qufeng compound alleviates atopic dermatitis via TLR4/MyD88/NF-κB signaling pathway.
Glutamatergic neuronal activity regulates angiogenesis and blood-retinal barrier maturation via Norrin/β-catenin signaling.
Bruceine B Displays Potent Antimyeloma Activity by Inducing the Degradation of the Transcription Factor c-Maf.
Downregulation of PTPRT elevates the expression of survivin and promotes the proliferation, migration, and invasion of lung adenocarcinoma.
Epigenetic addition of m(5)C to HBV transcripts promotes viral replication and evasion of innate antiviral responses.
Identification of important genes related to HVSMC proliferation and migration in graft restenosis based on WGCNA.
Targeting pyroptosis with nanoparticles to alleviate neuroinflammatory for preventing secondary damage following traumatic brain injury.
Surface characteristics and in vitro biocompatibility of titanium preserved in a vitamin C-containing saline storage solution.
Loss of Function of the Retinoblastoma Gene Affects Gap Junctional Intercellular Communication and Cell Fate in Osteoblasts.
miR-26a exerts broad-spectrum antiviral effects via the enhancement of RIG-I-mediated type I interferon response by targeting USP15.
A conformational selection mechanism of flavivirus NS5 for species-specific STAT2 inhibition.
Network pharmacology and experimental validation on yangjing zhongyu decoction against diminished ovarian reserve.
Tumor-associated macrophage-derived exosomal miR-513b-5p is a target of jianpi yangzheng decoction for inhibiting gastric cancer.
Fuzheng Huayu recipe alleviates liver fibrosis via inhibiting NLRP3 inflammasome activation in macrophages.
Inhibitory effect of Lonicera japonica-derived exosomal miR2911 on human papilloma virus.
Lobelia chinensis Lour inhibits the progression of hepatocellular carcinoma via the regulation of the PTEN/AKT signaling pathway in vivo and in vitro.
Hepatoprotective efficacy and interventional mechanism of JianPi LiShi YangGan formula in acute-on-chronic liver failure.
Yang-Xin-Shu-Mai granule alleviates atherosclerosis by regulating macrophage polarization via the TLR9/MyD88/NF-κB signaling pathway.
Astragalus saponins protect against extrahepatic and intrahepatic cholestatic liver fibrosis models by activation of farnesoid X receptor.
PRMT3 methylates HIF-1α to enhance the vascular calcification induced by chronic kidney disease.
Alamandine attenuates ovariectomy-induced osteoporosis by promoting osteogenic differentiation via AMPK/eNOS axis.
ErZhiTianGui Decoction alleviates age-related ovarian aging by regulating mitochondrial homeostasis and inhibiting ferroptosis.
Melatonin regulates autophagy in granulosa cells from patients with premature ovarian insufficiency via activating Foxo3a.
Tripartite motif-containing protein 26 promotes colorectal cancer growth by inactivating p53.
Epigenetic inhibition of CTCF by HN1 promotes dedifferentiation and stemness of anaplastic thyroid cancer.
RNA-binding protein hnRNPU regulates multiple myeloma resistance to selinexor.
Upregulated Tβ4 expression in inflammatory bowel disease impairs the intestinal mucus barrier by inhibiting autophagy in mice.
Manipulating HGF signaling reshapes the cirrhotic liver niche and fills a therapeutic gap in regeneration mediated by transplanted stem cells.
Identification of FOXP3(+) epithelial cells contributing to pancreatic proliferation and angiogenesis.
Triclosan induces earlier puberty onset in female mice via interfering with L-type calcium channels and activating Pik3cd.
The role of estrogen receptors (ERs)-Notch pathway in thyroid toxicity induced by Di-2-ethylhexyl phthalate (DEHP) exposure: Population data and in vitro studies.
Intranasal oxytocin alleviates comorbid depressive symptoms in neuropathic pain via elevating hippocampal BDNF production in both female and male mice.
Synergistic anticancer effect by targeting CDK2 and EGFR-ERK signaling.
Oncostatin M/Oncostatin M Receptor Signal Induces Radiation-Induced Heart Fibrosis by Regulating SMAD4 in Fibroblast.
Individualized treatment with voriconazole in the Chinese population: Inflammation level as a novel marker for dose optimization.
Genome-wide meta-analysis, functional genomics and integrative analyses implicate new risk genes and therapeutic targets for anxiety disorders.
Excessive SOX8 reprograms energy and iron metabolism to prime hepatocellular carcinoma for ferroptosis.
Inhibition of the RBMS1/PRNP axis improves ferroptosis resistance-mediated oxaliplatin chemoresistance in colorectal cancer.
Electroacupuncture Promotes Nerve Regeneration and Functional Recovery Through Regulating lncRNA GAS5 Targeting miR-21 After Sciatic Nerve Injury.
Alisol A Exerts Neuroprotective Effects Against HFD-Induced Pathological Brain Aging via the SIRT3-NF-κB/MAPK Pathway.
Asiaticoside Attenuates Blood-Spinal Cord Barrier Disruption by Inhibiting Endoplasmic Reticulum Stress in Pericytes After Spinal Cord Injury.
Pyruvate kinase M2 regulates kidney fibrosis through pericyte glycolysis during the progression from acute kidney injury to chronic kidney disease.
Oncogenic lncRNA FAM215A promotes the malignant cell phenotypes of acute myeloid leukemia (AML) cell lines.
Interleukin-17 alleviates erastin-induced alveolar bone loss by suppressing ferroptosis via interaction between NRF2 and p-STAT3.
Involvement of PI3K/AKT Pathway in the Rapid Antidepressant Effects of Crocetin in Mice with Depression-Like Phenotypes.
Spindle and kinetochore-related complex subunit 3 has a protumour function in osteosarcoma by activating the Notch pathway.
Overexpression of PPM1B inhibited chemoresistance to temozolomide and proliferation in glioma cells.
Deep learning enables the discovery of a novel cuproptosis-inducing molecule for the inhibition of hepatocellular carcinoma.
Caffeic acid alleviates cerebral ischemic injury in rats by resisting ferroptosis via Nrf2 signaling pathway.
Efficacy of Ganshuang granules on non-alcoholic fatty liver and underlying mechanism: a network pharmacology and experimental verification.
A comprehensive analysis of the expression, immune infiltration, prognosis and partial experimental validation of CHST family genes in gastric cancer.
METTL3 promotes microglial inflammation via MEF2C in spinal cord injury.
Mutual antagonism of mouse-adaptation mutations in HA and PA proteins on H9N2 virus replication.
Drug repurposing screen identifies vidofludimus calcium and pyrazofurin as novel chemical entities for the development of hepatitis E interventions.
Icariside II prevents kidney fibrosis development in chronic kidney disease by promoting fatty acid oxidation.
Epigallocatechin-3-gallate promotes wound healing response in diabetic mice by activating keratinocytes and promoting re-epithelialization.
Spinal interleukin-24 contributes to neuropathic pain after peripheral nerve injury through interleukin-20 receptor2 in mice.
Ultrasound-mediated HGF Gene Microbubbles Mitigate Hyperkinetic Pulmonary Arterial Hypertension in Rabbits.
Sesquiterpene from Artemisia argyi seed extracts: A new anti-acute peritonitis agent that suppresses the MAPK pathway and promotes autophagy.
Aurora kinase A-mediated phosphorylation triggers structural alteration of Rab1A to enhance ER complexity during mitosis.
ABLIM1, a novel ubiquitin E3 ligase, promotes growth and metastasis of colorectal cancer through targeting IĸBα ubiquitination and activating NF-ĸB signaling.
LncNFYB promotes the proliferation of rheumatoid arthritis fibroblast-like synoviocytes via LncNFYB/ANXA2/ERK1/2 axis.
Targeting blood brain barrier-Remote ischemic conditioning alleviates cognitive impairment in female APP/PS1 rats.
Polygalacic acid attenuates cognitive impairment by regulating inflammation through PPARγ/NF-κB signaling pathway.
PGAM5 knockout causes depressive-like behaviors in mice via ATP deficiency in the prefrontal cortex.
The G protein-coupled estrogen receptor of the trigeminal ganglion regulates acute and chronic itch in mice.
Enriched environment ameliorates fear memory impairments induced by sleep deprivation via inhibiting PIEZO1/calpain/autophagy signaling pathway in the basal forebrain.
Huangqin Decoction Delays Progress of Colitis-Associated Carcinogenesis by Regulating Nrf2/HO-1 Antioxidant Signal Pathway in Mice.
Promoting effect and immunologic role of secretogranin II on bladder cancer progression via regulating MAPK and NF-κB pathways.
Cholesterol depletion inhibits rabies virus infection by restricting viral adsorption and fusion.
Porcine delta coronavirus inhibits NHE3 activity of porcine intestinal epithelial cells through miR-361-3p/NHE3 regulatory axis.
Lead exposure induced transgenerational developmental neurotoxicity by altering genome methylation in Drosophila melanogaster.
Proteomic analysis reveals that cigarette smoke exposure diminishes ovarian reserve in mice by disrupting the CREB1-mediated ovarian granulosa cell proliferation-apoptosis balance.
Safranal acts as a neurorestorative agent in rats with cerebral ischemic stroke via upregulating SIRT1.
Downregulation of NEBL promotes migration and invasion of clear cell renal cell carcinoma by inducing epithelial-mesenchymal transition.
Aurora kinase B disruption suppresses pathological retinal angiogenesis by affecting cell cycle progression.
Natural isoflavone glabridin targets PI3Kγ as an adjuvant to increase the sensitivity of MDA-MB-231 to tamoxifen and DU145 to paclitaxel.
Transcription factor c-Maf drives macrophages to promote hypertrophic scar formation.
The long noncoding RNA HNF1A-AS1 with dual functions in the regulation of cytochrome P450 3A4.
Upregulation of TRIM16 mitigates doxorubicin-induced cardiotoxicity by modulating TAK1 and YAP/Nrf2 pathways in mice.
4-octyl itaconate protects against oxidative stress-induced liver injury by activating the Nrf2/Sirt3 pathway through AKT and ERK1/2 phosphorylation.
Deferoxamine reduces endothelial ferroptosis and protects cerebrovascular function after experimental traumatic brain injury.
Improvement of astrocytic gap junction involves the anti-depressive effect of celecoxib through inhibition of NF-κB.
Targeting CD38/ ADP-ribosyl cyclase as a novel therapeutic strategy for identification of three potent agonists for leukopenia treatment.
NSD2 modulates Drp1-mediated mitochondrial fission in chronic renal allograft interstitial fibrosis by methylating STAT1.
G-Quadruplex/Hemin DNAzyme-Functionalized Silver Nanoclusters with Synergistic Antibacterial and Wound Healing Capabilities for Infected Wound Management.
Downregulation of CPSF6 leads to global mRNA 3' UTR shortening and enhanced antiviral immune responses.
TRIM72 restricts lyssavirus infection by inducing K48-linked ubiquitination and proteasome degradation of the matrix protein.
ER stress elicits non-canonical CASP8 (caspase 8) activation on autophagosomal membranes to induce apoptosis.
Molecular mechanism of honeysuckle + forsythia in treatment of acute lung injury based on network pharmacology.
NLRP3 activation in macrophages promotes acute intestinal injury in neonatal necrotizing enterocolitis.
ARHGAP18 is Upregulated by Transcription Factor GATA1 Promotes the Proliferation and Invasion in Hepatocellular Carcinoma.
The novel antibody fusion protein rhNRG1-HER3i promotes heart regeneration by enhancing NRG1-ERBB4 signaling pathway.
mTORC1 regulates the metabolic switch of postnatal cardiomyocytes during regeneration.
Isoflavones isolated from chickpea sprouts alleviate ovariectomy-induced osteoporosis in rats by dual regulation of bone remodeling.
Targeting ROCK1 in diabetic kidney disease: Unraveling mesangial fibrosis mechanisms and introducing myricetin as a novel antagonist.
GIMAP7 inhibits epithelial-mesenchymal transition and glycolysis in lung adenocarcinoma cells via regulating the Smo/AMPK signaling pathway.
A novel biomarker of fibrofatty replacement in dystrophinopathies identified by integrating transcriptome, magnetic resonance imaging, and pathology data.
Near-infrared light controlled protein degradation by photo-caged lenalidomide and pomalidomide.
Sulfotransferase SULT2B1 facilitates colon cancer metastasis by promoting SCD1-mediated lipid metabolism.
The involvement of RNA N6-methyladenosine and histone methylation modification in decidualization and endometriosis-associated infertility.
Hyaluronic Acid-Based Reactive Oxygen Species-Responsive Multifunctional Injectable Hydrogel Platform Accelerating Diabetic Wound Healing.
Tumor suppressive function of IGF2BP1 in gastric cancer through decreasing MYC.
Deubiquitinating enzyme PSMD7 promotes bladder cancer development: Involvement of RAB1A stabilization.
MPDZ is associated with immune infiltration and regulates migration and invasion by switching YAP1 phosphorylation in colorectal cancer.
BHLHE40 Inhibits Ferroptosis in Pancreatic Cancer Cells via Upregulating SREBF1.
Phosphorylation of RGS16 at Tyr168 promote HBeAg-mediated macrophage activation by ERK pathway to accelerate liver injury.
DSPE-PEG(2000)-methotrexate nanoparticles encapsulating phenobarbital sodium kill cancer cells by inducing pyroptosis.
Functional analysis of Cdc20 reveals a critical role of CRY box in mitotic checkpoint signaling.
MTHFD1 regulates the NADPH redox homeostasis in MYCN-amplified neuroblastoma.
NOTCH1 as a Negative Regulator of Avian Adipocyte Differentiation: Implications for Fat Deposition.
An oncolytic virus-T cell chimera for cancer immunotherapy.
Saracatinib inhibits necroptosis and ameliorates psoriatic inflammation by targeting MLKL.
The Schwann cell-specific G-protein Gαo (Gnao1) is a cell-intrinsic controller contributing to the regulation of myelination in peripheral nerve system.
METTL14-mediated m6A epitranscriptomic modification contributes to chemotherapy-induced neuropathic pain by stabilizing GluN2A expression via IGF2BP2.
Inhibition of Cpeb3 ribozyme elevates CPEB3 protein expression and polyadenylation of its target mRNAs and enhances object location memory.
Sulbactam protects neurons against double neurotoxicity of amyloid beta and glutamate load by upregulating glial glutamate transporter 1.
Luteolin blocks the ROS/PI3K/AKT pathway to inhibit mesothelial-mesenchymal transition and reduce abdominal adhesions.
Tetrandrine downregulates TRPV2 expression to ameliorate myocardial ischemia/reperfusion injury in rats via regulation of cardiomyocyte apoptosis, calcium homeostasis and mitochondrial function.
Inhibiting LCN2 can suppress the development of NSCLC by promoting ferroptosis.
Dynamic palmitoylation of STX11 controls injury-induced fatty acid uptake to promote muscle regeneration.
Macrophages Promote Subtype Conversion and Endocrine Resistance in Breast Cancer.
HAND factors regulate cardiac lineage commitment and differentiation from human pluripotent stem cells.
Defining the mechanisms and properties of post-transcriptional regulatory disordered regions by high-throughput functional profiling.
Cabergoline as a Novel Strategy for Post-Pregnancy Breast Cancer Prevention in Mice and Human.
Altered nuclear envelope homeostasis is a key pathogenic event in C9ORF72-linked ALS/FTD.
Hippocampal estrogens rescued the decline of synaptic plasticity after surgery and anesthesia by inhibiting microglia overactivation.
CircMTA2 Drives Gastric Cancer Progression through Suppressing MTA2 Degradation via Interacting with UCHL3.
Improvement of idiopathic pulmonary fibrosis through a combination of Astragalus radix and Angelica sinensis radix via mammalian target of rapamycin signaling pathway-induced autophagy in rat.
ENO2 promotes anoikis resistance in anaplastic thyroid cancer by maintaining redox homeostasis.
SMG9 is a novel prognostic-related biomarker in glioma correlating with ferroptosis and immune infiltrates.
Ginseng-Sanqi-Chuanxiong (GSC) extracts attenuate d-galactose-induced vascular aging in mice via inhibition of endothelial progenitor cells senescence.
Astragalus polysaccharide improves diabetic ulcers by promoting M2-polarization of macrophages to reduce excessive inflammation via the β-catenin/ NF-κB axis at the late phase of wound-healing.
Driving effect of P16 methylation on telomerase reverse transcriptase-mediated immortalization and transformation of normal human fibroblasts.
Mitochondria-Associated Protein FgNdk1 Regulates the Development, Pathogenicity, and SDHI Fungicide Sensitivity of Fusarium graminearum by Interacting with Succinate Dehydrogenase.
Molecular mechanism of human ISG20L2 for the ITS1 cleavage in the processing of 18S precursor ribosomal RNA.
Multi-omics analysis for ferroptosis-related genes as prognostic factors in cutaneous melanoma.
Integrin α(4) Positive Subpopulation in Adipose Derived Stem Cells Effectively Reduces Infarct Size through Enhanced Engraftment into Myocardial Infarction.
hnRNPA2B1 represses the disassembly of arsenite-induced stress granules and is essential for male fertility.
Schwann cell promotes macrophage recruitment through IL-17B/IL-17RB pathway in injured peripheral nerves.
Pharmacological inhibition of neddylation impairs long interspersed element 1 retrotransposition.
KEAP1 promotes anti-tumor immunity by inhibiting PD-L1 expression in NSCLC.
Machine learning reveals diverse cell death patterns in lung adenocarcinoma prognosis and therapy.
Cross-Oxygen Gradients Transcriptomic Comparison Revealed the Central Role of MAPK and Hippo in Hypoxia-Mediated Mammary Proliferation Inhibition.
SKP alleviates the ferroptosis in diabetic kidney disease through suppression of HIF-1α/HO-1 pathway based on network pharmacology analysis and experimental validation.
ACADL-YAP axis activity in non-small cell lung cancer carcinogenicity.
JianPiYiShen formula prevents cisplatin-induced acute kidney injury in mice by improving necroptosis through MAPK pathway.
Inhibition of ferroptosis reverses heart failure with preserved ejection fraction in mice.
PRMT1-mediated PGK1 arginine methylation promotes colorectal cancer glycolysis and tumorigenesis.
WSB1, as an E3 ligase, restrains myocardial ischemia-reperfusion injury by activating β-catenin signaling via promoting GSK3β ubiquitination.
A Marine Natural Product, Harzianopyridone, as an Anti-ZIKV Agent by Targeting RNA-Dependent RNA Polymerase.
Heme Oxygenase-1 Regulates Zearalenone-Induced Oxidative Stress and Apoptosis in Sheep Follicular Granulosa Cells.
Tumoral C2 Regulates the Tumor Microenvironment by Increasing the Ratio of M1/M2 Macrophages and Tertiary Lymphoid Structures to Improve Prognosis in Melanoma.
A co-assembly platform engaging macrophage scavenger receptor A for lysosome-targeting protein degradation.
Interleukin-6 trans-signaling regulates monocyte chemoattractant protein-1 production in immune-mediated necrotizing myopathy.
MYC-dependent MiR-7-5p regulated apoptosis and autophagy in diffuse large B cell lymphoma by targeting AMBRA1.
Discovery of D25, a Potent and Selective MNK Inhibitor for Sepsis-Associated Acute Spleen Injury.
Design, Synthesis, and Biological Evaluation of Dual Inhibitors of EGFR(L858R/T790M)/ACK1 to Overcome Osimertinib Resistance in Nonsmall Cell Lung Cancers.
Protective Effect of Vitamin K2 (MK-7) on Acute Lung Injury Induced by Lipopolysaccharide in Mice.
SPOCK2 modulates neuropathic pain by interacting with MT1-MMP to regulate astrocytic MMP-2 activation in rats with chronic constriction injury.
Advanced oxidation protein products attenuate the autophagy-lysosome pathway in ovarian granulosa cells by modulating the ROS-dependent mTOR-TFEB pathway.
Phospho-eIF4E stimulation regulates coronavirus entry by selective expression of cell membrane-residential factors.
Porcine reproductive and respiratory syndrome virus triggers Golgi apparatus fragmentation-mediated autophagy to facilitate viral self-replication.
N-terminal acetyltransferase 6 facilitates enterovirus 71 replication by regulating PI4KB expression and replication organelle biogenesis.
Porcine deltacoronavirus nsp5 antagonizes type I interferon signaling by cleaving IFIT3.
Polyethylenimine Triggers Dll4 Degradation to Regulate Angiogenesis In Vitro.
ALDH2 deficiency exacerbates MCD-diet induced MASLD by modulating bile acid metabolism.
P21 resists ferroptosis in osteoarthritic chondrocytes by regulating GPX4 protein stability.
Kupffer cells abrogate homing and repopulation of allogeneic hepatic progenitors in injured liver site.
Cepharanthine analogs mining and genomes of Stephania accelerate anti-coronavirus drug discovery.
Nucleoredoxin Redox Interactions Are Sensitized by Aging and Potentiated by Chronic Alcohol Consumption in the Mouse Liver.
IP3R2-mediated Ca(2+) release promotes LPS-induced cardiomyocyte pyroptosis via the activation of NLRP3/Caspase-1/GSDMD pathway.
Single-Cell Transcriptomics Reveals the Heterogeneity of the Immune Landscape of IDH-Wild-Type High-Grade Gliomas.
Mitochondrial-related genes PDK2, CHDH, and ALDH5A1 served as a diagnostic signature and correlated with immune cell infiltration in ulcerative colitis.
Tumorigenesis of basal muscle invasive bladder cancer was mediated by PTEN protein degradation resulting from SNHG1 upregulation.
N6-methyladenosine modification of B7-H3 mRNA promotes the development and progression of colorectal cancer.
TBX15 facilitates malignant progression of glioma by transcriptional activation of TXDNC5.
CREB3L4 promotes hepatocellular carcinoma progression and decreases sorafenib chemosensitivity by promoting RHEB-mTORC1 signaling pathway.
NatD epigenetically activates FOXA2 expression to promote breast cancer progression by facilitating MMP14 expression.
YTHDF2-mediated circYAP1 drives immune escape and cancer progression through activating YAP1/TCF4-PD-L1 axis.
Inhibition of RIPK1 alleviating vascular smooth muscle cells osteogenic transdifferentiation via Runx2.
Exploiting the Cullin E3 Ligase Adaptor Protein SKP1 for Targeted Protein Degradation.
Protein phosphatase 1 regulatory subunit 15 A promotes translation initiation and induces G2M phase arrest during cuproptosis in cancers.
Pro-ferroptotic signaling promotes arterial aging via vascular smooth muscle cell senescence.
High-fat diet promotes prostate cancer metastasis via RPS27.
Deciphering m6A signatures in hepatocellular carcinoma: Single-cell insights, immune landscape, and the protective role of IGFBP3.
DOPAMINE D4 RECEPTOR DOWN-REGULATES RENAL SODIUM CHLORIDE COTRANSPORTER VIA UBIQUITINATION-ASSOCIATED LYSOSOME DEGRADATION.
Pharmacological inhibition of ICOS attenuates the protective effect of exercise on cardiac fibrosis induced by isoproterenol.
Exploring the importance of m5c in the diagnosis and subtype classification of COPD using the GEO database.
Hic-5 regulates extracellular matrix-associated gene expression and cytokine secretion in cancer associated fibroblasts.
A novel tsRNA-5008a promotes ferroptosis in cardiomyocytes that causes atrial structural remodeling predisposed to atrial fibrillation.
YTHDF2 alleviates microglia activation via promoting circHIPK2 degradation.
Disrupting the gut microbiota/metabolites axis by Di-(2-ethylhexyl) phthalate drives intestinal inflammation via AhR/NF-κB pathway in mice.
Methotrexate-based PROTACs as DHFR-specific chemical probes.
Integrated network pharmacology and metabolomics reveal the action mechanisms of vincristine combined with celastrol against colon cancer.
Synergistic and attenuated effects and molecular biological mechanisms of Shouhui Tongbian capsule in the treatment of slow transit constipation based on UPLC-MS/MS, network pharmacology and animal experimental validation.
Comprehensive analysis of the protein phosphatase 2A regulatory subunit B56ε in pan-cancer and its role and mechanism in hepatocellular carcinoma.
ACE2 improves endothelial cell function and reduces acute lung injury by downregulating FAK expression.
Blocking brown adipocyte β(3)-adrenoceptor attenuates blood-spinal cord barrier impairment and chronic postsurgical pain in a rat model of preoperative stress.
FTO attenuates LPS-induced acute kidney injury by inhibiting autophagy via regulating SNHG14/miR-373-3p/ATG7 axis.
The TGFβ1/SMADs/Snail1 signaling axis mediates pericyte-derived fibrous scar formation after spinal cord injury.
Xingnaojing injection alleviates cerebral ischemia/reperfusion injury through regulating endoplasmic reticulum stress in Vivo and in Vitro.
Pterostilbene attenuates heart failure by inhibiting myocardial ferroptosis through SIRT1/GSK-3β/GPX4 signaling pathway.
Eriocalyxin B alleviated ischemic cerebral injury by limiting microglia-mediated excessive neuroinflammation in mice.
ZNF460-mediated circRPPH1 promotes TNBC progression through ITGA5-induced FAK/PI3K/AKT activation in a ceRNA manner.
Comprehensive analysis of disulfidptosis-related genes: a prognosis model construction and tumor microenvironment characterization in clear cell renal cell carcinoma.
3D Spheroids Facilitate Differentiation of Human Adipose-Derived Mesenchymal Stem Cells into Hepatocyte-Like Cells via p300-Mediated H3K56 Acetylation.
Microneme-located VP2 in Eimeria acervulina elicits effective protective immunity against infectious bursal disease virus.
Aggresome formation promotes ASK1/JNK signaling activation and stemness maintenance in ovarian cancer.
Human Parathyroid Hormone (1-34) accelerates skin wound healing through inducing cell migration via up-regulating the expression of Rac1.
Orexin-A alleviates ferroptosis by activating the Nrf2/HO-1 signaling pathway in traumatic brain injury.
A methylation-phosphorylation switch controls EZH2 stability and hematopoiesis.
Self-Healing Micro Arc Oxidation and Dicalcium Phosphate Dihydrate Double-Passivated Coating on Magnesium Membrane for Enhanced Bone Integration Repair.
Jingfang Granule mitigates Coxsackievirus B3-induced myocardial damage by modulating mucolipin 1 expression.
Jiawei Maxing Shigan Tang alleviates radiation-induced lung injury via TGF-β1/Smad signaling pathway mediated by regulatory T cells.
DNA hypomethylation-mediated upregulation of GADD45B facilitates airway inflammation and epithelial cell senescence in COPD.
Ferroptosis as a Potential Therapeutic Target for Reducing Inflammation and Corneal Scarring in Bacterial Keratitis.
CP41, a novel curcumin analogue, induces apoptosis in endometrial cancer cells by activating the H3F3A/ proteasome-MAPK signaling pathway and enhancing oxidative stress.
The role and mechanism of NLRP3 in wasp venom-induced acute kidney injury.
miR-6881-3p contributes to diminished ovarian reserve by regulating granulosa cell apoptosis by targeting SMAD4.
Therapeutic application of human type 2 innate lymphoid cells via induction of granzyme B-mediated tumor cell death.
Down-expression of miR-494-3p in senescent osteocyte-derived exosomes inhibits osteogenesis and accelerates age-related bone loss via PTEN/PI3K/AKT pathway.
Exploring the Osteogenic Potential of Zinc-Doped Magnesium Phosphate Cement (ZMPC): A Novel Material for Orthopedic Bone Defect Repair.
LncRNA AFAP1-AS1 Promotes Oral Squamous Cell Carcinoma Development by Ubiquitin-Mediated Proteolysis.
Peptidylprolyl isomerase D circular RNA sensitizes breast cancer to trastuzumab through remodeling HER2 N4-acetylcytidine modification.
OGT-induced O-GlcNAcylation of NEK7 protein aggravates osteoarthritis progression by enhancing NEK7/NLRP3 axis.
Identification of a novel nonsense mutation in α-galactosidase A that causes Fabry disease in a Chinese family.
Shen Shuai II recipe improves renal hypoxia to attenuate renal injury in 5/6 renal ablation/infarction rats and effect evaluation using blood oxygenation level-dependent functional magnetic resonance imaging.
Ginsenoside Rg1 mitigates cerebral ischaemia/reperfusion injury in mice by inhibiting autophagy through activation of mTOR signalling.
Engineered low-pathogenic Helicobacter pylori as orally tumor immunomodulators for the stimulation of systemic immune response.
Comprehensive pan-cancer analysis unveils the significant prognostic value and potential role in immune microenvironment modulation of TRIB3.
Downregulation of ABLIM3 confers to the metastasis of neuroblastoma via regulating the cell adhesion molecules pathway.
Coxiella burnetii effector CvpE maintains biogenesis of Coxiella-containing vacuoles by suppressing lysosome tubulation through binding PI(3)P and perturbing PIKfyve activity on lysosomes.
The mechanism of α2-macroglobulin against oxidative stress and promoting cell proliferation in intervertebral disc degeneration.
The African swine fever virus MGF300-4L protein is associated with viral pathogenicity by promoting the autophagic degradation of IKKβ and increasing the stability of IκBα.
Effectiveness of a broad-spectrum bivalent mRNA vaccine against SARS-CoV-2 variants in preclinical studies.
Berberine chloride suppresses pancreatic adenocarcinoma proliferation and growth by targeting inflammation-related genes: an in silico analysis with in vitro and vivo validation.
Inhibition of LSD1 via SP2509 attenuated the progression of rheumatoid arthritis.
Characterization of circRNA expression profiles associated with non-Mendelian inheritance in feather growth of chickens.
β-Elemene induced ferroptosis via TFEB-mediated GPX4 degradation in EGFR wide-type non-small cell lung cancer.
Dapagliflozin attenuates LPS-induced myocardial injury by reducing ferroptosis.
Long noncoding RNA ANRIL alleviates hypoxia-induced pulmonary microvascular endothelial cell damage.
PD-L1 Expression Is Increased in LPS-Induced Acute Respiratory Distress Syndrome by PI3K-AKT-Egr-1/C/EBPδ Signaling Pathway.
TRIM38 Induced in Respiratory Syncytial Virus-infected Cells Downregulates Type I Interferon Expression by Competing with TRIM25 to Bind RIG-I.
MiR-425-5p suppression of Crebzf regulates oocyte aging via chromatin modification.
The classical D1 dopamine receptor antagonist SCH23390 is a functional sigma-1 receptor allosteric modulator.
Isobavachalcone induces hepatotoxicity in zebrafish embryos and HepG2 cells via the System Xc(-)-GSH-GPX4 signaling pathway in ferroptosis response.
Environmentally relevant levels of Cd and Mo coexposure induces ferroptosis and excess ferritinophagy through AMPK/mTOR axis in duck myocardium.
The combination of berberine and isoliquiritigenin synergistically improved adipose inflammation and obesity-induced insulin resistance.
T-cell immunoglobulin and mucin 1 (TIM-1) mediates infection of Hantaan virus in Jurkat T cells.
Localized, highly efficient secretion of signaling proteins by migrasomes.
Obstructive Sleep Apnea Plasma-Derived Exosomes Mediate Cognitive Impairment Through Hippocampal Neuronal Cell Pyroptosis.
MUC16 can Predict the Pregnancy Outcomes in Human and Intraperitoneal Administration of MUC16 can Rescue Pregnancy Losses in Mouse Models.
Approaches to selective and potent inhibition of glioblastoma by vanadyl complexes: Inducing mitotic catastrophe and methuosis.
Characterization and noncovalent inhibition of the K63-deubiquitinase activity of SARS-cov-2 PLpro.
Geniposide effectively safeguards HT22 cells against Aβ-induced damage by activating mitophagy via the PINK1/Parkin signaling pathway.
Two Undescribed Coumarins from Notopterygium Incisum with Anti-Inflammatory Activity.
Bulk and single-cell transcriptome profiling identify potential cellular targets of the long noncoding RNA Gas5 in renal fibrosis.
The dual effects of dexmedetomidine on intestinal barrier and intestinal motility during sepsis.
A novel surface marker CD49d promotes TNF expression in oyster agranulocytes by mediating the MAPK pathway.
CXCR4-mediated neutrophil dynamics in periodontitis.
Lactate dehydrogenase B as a metabolism-related marker for immunotherapy in head and neck squamous cell carcinoma.
CKB Promotes Mitochondrial ATP Production by Suppressing Permeability Transition Pore.
Ginsenoside Rg1 Regulates Immune Microenvironment and Neurological Recovery After Spinal Cord Injury Through MYCBP2 Delivery via Neuronal Cell-Derived Extracellular Vesicles.
Reversing MET-Mediated Resistance in Oncogene-Driven NSCLC by MET-Activated Wnt Condensative Prodrug.
Inorganic Biomaterials Shape the Transcriptome Profile to Induce Endochondral Differentiation.
Preventive effects of lactoferrin on acute alcohol-induced liver injury via iron chelation and regulation of iron metabolism.
Nicotinamide metabolism face-off between macrophages and fibroblasts manipulates the microenvironment in gastric cancer.
Hepatitis B virus core protein as a Rab-GAP suppressor driving liver disease progression.
A positive FOXP3/lncRNA SNHG1 feedback axis ameliorates cardiomyocytes hypertrophy by negatively regulating Parkin-mediated mitophagy.
Wedelolactone suppresses breast cancer growth and metastasis via regulating TGF-β1/Smad signaling pathway.
Cellular senescence-Related genes define the immune microenvironment and molecular characteristics in severe asthma patients.
Exploration and validation of therapeutic molecules for rheumatoid arthritis based on ferroptosis-related genes.
Multi-omics and chemical profiling approaches to understand the material foundation and pharmacological mechanism of sophorae tonkinensis radix et rhizome-induced liver injury in mice.
Leonurus japonicus Houtt. modulates neuronal apoptosis in intracerebral hemorrhage: Insights from network pharmacology and molecular docking.
Rosmarinic acid alleviates toosendanin-induced liver injury through restoration of autophagic flux and lysosomal function by activating JAK2/STAT3/CTSC pathway.
USP7 cardiomyocyte specific knockout causes disordered mitochondrial biogenesis and dynamics and early neonatal lethality in mice.
METTL3-mediated upregulation of FAM135B promotes EMT of esophageal squamous cell carcinoma via regulating the Wnt/β-catenin pathway.
Fusobacterium nucleatum induces oxaliplatin resistance by inhibiting ferroptosis through E-cadherin/β-catenin/GPX4 axis in colorectal cancer.
The use of human iPSC-derived alveolar organoids to explore SARS-CoV-2 variant infections and host responses.
Statins Prevent the Deleterious Consequences of Placental Chemerin Upregulation in Preeclampsia.
YAP1-activated ZNF131 promotes hepatocellular carcinoma cell proliferation through transcriptional regulation of PAIP1.
RAE1 promotes gastric carcinogenesis and epithelial-mesenchymal transition.
Endothelial H(2)S-AMPK dysfunction upregulates the angiocrine factor PAI-1 and contributes to lung fibrosis.
The LINC complex ensures accurate centrosome positioning during prophase.
Knockout of Shcbp1 sensitizes immunotherapy by regulating α-SMA positive cancer-associated fibroblasts.
Human milk exosome-derived circDNAJB6 improves bronchopulmonary dysplasia model by promoting DNAJB6 gene transcription.
Cytoplasmic localization of SETDB1‑induced Warburg effect via c‑MYC‑LDHA axis enhances migration and invasion in breast carcinoma.
A mutation in TBXT causes congenital vertebral malformations in humans and mice.
PEDF protects retinal pigment epithelium from ferroptosis and ameliorates dry AMD-like pathology in a murine model.
SIBP-03, a novel anti-HER3 antibody, exerts antitumor effects and synergizes with EGFR- and HER2-targeted drugs.
Chemokine CCL2 promotes cardiac regeneration and repair in myocardial infarction mice via activation of the JNK/STAT3 axis.
Effects of down-regulated carbonic anhydrase 8 on cell survival and glucose metabolism in human colorectal cancer cell lines.
LncRNA HOTTIP regulates TLR4 promoter methylation by recruiting H3K4 methyltransferase MLL1 to affect apoptosis and inflammatory response of fibroblast-like synoviocyte in rheumatoid arthritis.
Gallic acid promotes ferroptosis in hepatocellular carcinoma via inactivating Wnt/β-catenin signaling pathway.
Toosendanin induces hepatotoxicity by restraining autophagy and lysosomal function through inhibiting STAT3/CTSC axis.
Ganoderic acids alleviate atherosclerosis by inhibiting macrophage M1 polarization via TLR4/MyD88/NF-κB signaling pathway.
Blood RNA-sequencing analysis in acrylamide-induced neurotoxicity and depressive symptoms in rats.
Excess iron accumulation mediated senescence in diabetic kidney injury.
Pimpinellin ameliorates macrophage inflammation by promoting RNF146-mediated PARP1 ubiquitination.
Acteoside ameliorates learning and memory impairment in APP/PS1 transgenic mice by increasing Aβ degradation and inhibiting tau hyperphosphorylation.
Inhibiting RIPK1-driven neuroinflammation and neuronal apoptosis mitigates brain injury following experimental subarachnoid hemorrhage.
Enhanced osteogenic and antibacterial properties of titanium implant surface modified with Zn-incorporated nanowires: Preclinical in vitro and in vivo investigations.
Transcriptome analysis reveals therapeutic potential of NAMPT in protecting against abdominal aortic aneurysm in human and mouse.
METTL3-mediated RanGAP1 promotes colorectal cancer progression through the MAPK pathway by recruiting YTHDF1.
Neuroinvasive virus facilitates viral replication by employing lipid droplets to reduce arachidonic acid-induced ferroptosis.
Deep-targeted gene sequencing reveals ARID1A mutation as an important driver of glioblastoma.
Carpesii fructus extract exhibits neuroprotective effects in cellular and Caenorhabditis elegans models of Parkinson's disease.
Circular RNA PTP4A2 regulates microglial polarization through STAT3 to promote neuroinflammation in ischemic stroke.
Anti-PD-1 treatment protects against seizure by suppressing sodium channel function.
Pleiotrophin inhibited chondrogenic differentiation potential of dental pulp stem cells.
RUNX2 mutation inhibits the cellular senescence of dental follicle cells via ERK signalling pathway.
Trk-fused gene plays a critical role in diet-induced adipose tissue expansion and is also involved in thyroid hormone action.
UBE2J1 promotes ALV-A proviral DNA synthesis through the STAT3/IRF1 signaling pathway.
Hepatocyte-derived exosomes deliver the lncRNA CYTOR to hepatic stellate cells and promote liver fibrosis.
Bilirubin ameliorates osteoarthritis via activating Nrf2/HO-1 pathway and suppressing NF-κB signalling.
Rapamycin inhibits B16 melanoma cell viability invitro and invivo by inducing autophagy and inhibiting the mTOR/p70‑S6k pathway.
Lipin-1 deficiency deteriorates defect of fatty acid β-oxidation and lipid-related kidney damage in diabetic kidney disease.
Characterization and function of PTEN-induced putative kinase 1 (PINK1) in process of Zinc alleviates hepatic lipid deposition of yellow catfish (Pelteobagrus fulvidraco).
FXR1 stabilizes SNORD63 to regulate blood-tumor barrier permeability through SNORD63 mediated 2'-O-methylation of POU6F1.
CircNOP14 increases the radiosensitivity of hepatocellular carcinoma via inhibition of Ku70-dependent DNA damage repair.
VDRA downregulate β-catenin/Smad3 and DNA damage and repair associated with improved prognosis in ccRCC patients.
Chloroxine inhibits pancreatic cancer progression through targeted antagonization of the PI3K/AKT/mTOR signaling pathway.
Theileria annulata subtelomere-encoded variable secreted protein-TA05560 interacts with bovine RNA binding motif protein 39 (RBM39).
TGF-β2-induced alterations of m6A methylation in hTERT RPE-1 cells.
Excessive processing and acetylation of OPA1 aggravate age-related hearing loss via the dysregulation of mitochondrial dynamics.
TuBG1 promotes hepatocellular carcinoma via ATR/P53-apoptosis and cycling pathways.
Cevanine-type alkaloids from the bulbs of Fritillaria unibracteata var. wabuensis and their antifibrotic activities in vitro.
Optogenetic manipulation of lysosomal physiology and autophagy-dependent clearance of amyloid beta.
Pseudorabies virus gM and its homologous proteins in herpesviruses induce mitochondria-related apoptosis involved in viral pathogenicity.
African swine fever virus pB318L, a trans-geranylgeranyl-diphosphate synthase, negatively regulates cGAS-STING and IFNAR-JAK-STAT signaling pathways.
Clinical and molecular characterization of 10 Chinese children with congenital adrenal hyperplasia due to 11beta-hydroxylase deficiency.
Person-specific differences in ubiquitin-proteasome mediated proteostasis in human neurons.
DOCK2 Promotes Atherosclerosis by Mediating the Endothelial Cell Inflammatory Response.
Nanoreceptors promote mutant p53 protein degradation by mimicking selective autophagy receptors.
Platycodon grandiflorus polysaccharide inhibits the inflammatory response of 3D4/21 cells infected with PCV2.
Identification and validation of an immunotherapeutic signature for colon cancer based on the regulatory patterns of ferroptosis and their association with the tumor microenvironment.
GDI2 deletion alleviates neurodegeneration and memory loss in the 5xFAD mice model of Alzheimer's disease.
Spermidine ameliorates osteoarthritis via altering macrophage polarization.
MT-TN mutations lead to progressive mitochondrial encephalopathy and promotes mitophagy.
LCP1-mediated cytoskeleton alterations involve in arsenite-triggered malignant phenotype of human immortalized prostate stromal cells.
Ginsenoside Rb1 alleviates 3-MCPD-induced renal cell pyroptosis by activating mitophagy.
Bisphenol S impairs mitochondrial function by targeting Myo19/oxidative phosphorylation pathway contributing to axonal and dendritic injury.
Methylmercury induces inflammatory response and autophagy in microglia through the activation of NLRP3 inflammasome.
Trilobatin attenuates cerebral ischaemia/reperfusion-induced blood-brain barrier dysfunction by targeting matrix metalloproteinase 9: The legend of a food additive.
Melittin induces autophagy to alleviate chronic renal failure in 5/6-nephrectomized rats and angiotensin II-induced damage in podocytes.
Iron overload increases the sensitivity of endometriosis stromal cells to ferroptosis via a PRC2-independent function of EZH2.
AKT2 deficiency alleviates doxorubicin-induced cardiac injury via alleviating oxidative stress in cardiomyocytes.
Identification of PKM2 as a pyroptosis-related key gene aggravates senile osteoporosis via the NLRP3/Caspase-1/GSDMD signaling pathway.
SAMHD1 dysfunction induces IL-34 expression via NF-κB p65 in neuronal SH-SY5Y cells.
NOTUM plays a bidirectionally modulatory role in the odontoblastic differentiation of human stem cells from the apical papilla through the WNT/β-catenin signaling pathway.
Engineered platelet-based immune engager for tumor post-surgery treatment.
Phenolics and terpenoids with good anti-inflammatory activity from the fruits of Amomum villosum and the anti-inflammatory mechanism of active diterpene.
5Z-7-Oxozaenol attenuates cuprizone-induced demyelination in mice through microglia polarization regulation.
Engagement of N(6)-methyladenisine methylation of Gng4 mRNA in astrocyte dysfunction regulated by CircHECW2.
Glutathione Depletion-Induced Versatile Nanomedicine for Potentiating the Ferroptosis to Overcome Solid Tumor Radioresistance and Enhance Immunotherapy.
The m6A methyltransferase METTL5 promotes neutrophil extracellular trap network release to regulate hepatocellular carcinoma progression.
The RNA-binding protein RBMS3 inhibits the progression of colon cancer by regulating the stability of LIMS1 mRNA.
Shen-Shuai-II-Recipe inhibits tubular inflammation by PPARα-mediated fatty acid oxidation to attenuate fibroblast activation in fibrotic kidneys.
Artesunate improves glucose and lipid metabolism in db/db mice by regulating the metabolic profile and the MAPK/PI3K/Akt signalling pathway.
Calorie restriction mimetic, resveratrol, attenuates hepatic ischemia and reperfusion injury through enhancing efferocytosis of macrophages via AMPK/STAT3/S1PR1 pathway.
Moderate replacement of fish oil with palmitic acid-stimulated mitochondrial fusion promotes β-oxidation by Mfn2 interacting with Cpt1α via its GTPase-domain.
Excessive fluoride induces ovarian function impairment by regulating levels of ferroptosis in fluorosis women and ovarian granulosa cells.
CXCL4/CXCR3 axis regulates cardiac fibrosis by activating TGF-β1/Smad2/3 signaling in mouse viral myocarditis.
Beta-Cell Tipe1 Orchestrates Insulin Secretion and Cell Proliferation by Promoting Gαs/cAMP Signaling via USP5.
RBMS1 Coordinates with the m(6)A Reader YTHDF1 to Promote NSCLC Metastasis through Stimulating S100P Translation.
A Nucleic Acid-Based LYTAC Plus Platform to Simultaneously Mediate Disease-Driven Protein Downregulation.
The surface morphology of Atractylodes macrocephala polysaccharide and its inhibitory effect on PCV2 replication.
Influence of Growth Differentiation Factor 15 on Intraocular Pressure in Mice.
TMAO promotes vascular endothelial cell pyroptosis via the LPEAT-mitophagy pathway.
Bile acids modified by the intestinal microbiota promote colorectal cancer growth by suppressing CD8(+) T cell effector functions.
GLUT3-mediated cigarette smoke-induced epithelial-mesenchymal transition in chronic obstructive pulmonary disease through the NF-kB/ZEB1 pathway.
A study on the significance of serine hydroxymethyl transferase expression and its role in bladder cancer.
G6PD maintains the VSMC synthetic phenotype and accelerates vascular neointimal hyperplasia by inhibiting the VDAC1-Bax-mediated mitochondrial apoptosis pathway.
STING inhibition suppresses microglia-mediated synapses engulfment and alleviates motor functional deficits after stroke.
Curcumin regulates autophagy through SIRT3-SOD2-ROS signaling pathway to improve quadriceps femoris muscle atrophy in KOA rat model.
Type III interferon inhibits bladder cancer progression by reprogramming macrophage-mediated phagocytosis and orchestrating effective immune responses.
Klotho exerts protection in chronic kidney disease associated with regulating inflammatory response and lipid metabolism.
Altered TFEB subcellular localization in nigral neurons of subjects with incidental, sporadic and GBA-related Lewy body diseases.
Irisin alters D-galactose-induced apoptosis by increasing caveolin-1 expression in C2C12 myoblasts and skeletal muscle fibroblasts.
Licochalcone A induces mitochondria-dependent apoptosis and interacts with venetoclax in acute myeloid leukemia.
Zinc remodels mitochondrial network through SIRT3/Mfn2-dependent mitochondrial transfer in ameliorating spinal cord injury.
Circulating tumor cells shielded with extracellular vesicle-derived CD45 evade T cell attack to enable metastasis.
Mechanism of Smilax china L. in the treatment of intrauterine adhesions based on network pharmacology, molecular docking and experimental validation.
Disrupted de novo pyrimidine biosynthesis impairs adult hippocampal neurogenesis and cognition in pyridoxine-dependent epilepsy.
The mechanisms of MicroRNA 21 in premature ovarian insufficiency mice with mesenchymal stem cells transplantation : The involved molecular and immunological mechanisms.
Activating SRC/MAPK signaling via 5-HT1A receptor contributes to the effect of vilazodone on improving thrombocytopenia.
Detailed phenotyping of Tbr1-2A-CreER knock-in mice demonstrates significant impacts on TBR1 protein levels and axon development.
The c-Abl-RACK1-FAK signaling axis promotes renal fibrosis in mice through regulating fibroblast-myofibroblast transition.
Glutamine Promotes Porcine Intestinal Epithelial Cell Proliferation through the Wnt/β-Catenin Pathway.
MATN2 overexpression suppresses tumor growth in ovarian cancer via PTEN/PI3K/AKT pathway.
Map-1a regulates Sertoli cell BTB dynamics through the cytoskeletal organization of microtubule and F-actin.
Shank3 deficiency elicits autistic-like behaviors by activating p38α in hypothalamic AgRP neurons.
SorCS2 is involved in promoting periodontitis-induced depression-like behaviour in mice.
Contributions of the Dachsous intracellular domain to Dachsous-Fat signaling.
Pretreatment with interleukin-15 attenuates inflammation and apoptosis by inhibiting NF-κB signaling in sepsis-induced myocardial dysfunction.
Mitophagy Regulates the Circadian Rhythms by Degrading NR1D1 in Simulated Microgravity and Isolation Environments.
Deubiquitination of CDC6 by OTUD6A promotes tumour progression and chemoresistance.
Therapeutic efficacy of a novel self-assembled immunostimulatory siRNA combining apoptosis promotion with RIG-I activation in gliomas.
The Planar Cell Polarity Protein Fat1 in Sertoli Cell Function.
Targeting PARP14 with lomitapide suppresses drug resistance through the activation of DRP1-induced mitophagy in multiple myeloma.
Sokotrasterol Sulfate Suppresses IFN-γ-Induced PD-L1 Expression by Inhibiting JAK Activity.
DEC1 is involved in circadian rhythm disruption-exacerbated pulmonary fibrosis.
Expression and functional significance of phosphoenolpyruvate carboxykinase 1 in uveal melanoma.
Iridium(III)-Based PD-L1 Agonist Regulates p62 and ATF3 for Enhanced Cancer Immunotherapy.
Unlocking the power of immunotherapy: Combinatorial delivery of plasmid IL-15 and gemcitabine to synergistically remodeling the tumor microenvironment.
Rosamultin ameliorates radiation injury via promoting DNA injury repair and suppressing oxidative stress in vitro and in vivo.
Positive selection CRISPR screens reveal a druggable pocket in an oligosaccharyltransferase required for inflammatory signaling to NF-κB.
Promoter hypomethylated PDZK1 acts as a tumorigenic gene in glioma by interacting with AKT1.
Distinct functions for the paralogous RBM41 and U11/U12-65K proteins in the minor spliceosome.
Diterpenoid tanshinones inhibit gastric cancer angiogenesis through the PI3K/Akt/mTOR signaling pathway.
Identification of different myofiber types in pigs muscles and construction of regulatory networks.
OTUD5 promotes the growth of hepatocellular carcinoma by deubiquitinating and stabilizing SLC38A1.
Exploring the Potential Mechanisms of Guanxinshutong Capsules in Treating Pathological Cardiac Hypertrophy based on Network Pharmacology, Computer-Aided Drug Design, and Animal Experiments.
TMC7 functions as a suppressor of Piezo2 in primary sensory neurons blunting peripheral mechanotransduction.
Endocytic activation and exosomal secretion of matriptase stimulate the second wave of EGF signaling to promote skin and breast cancer invasion.
Pharmacodynamic and Toxicity Studies of 6-Isopropyldithio-2'-guanosine Analogs in Acute T-Lymphoblastic Leukemia.
CMYC-initiated HNF1A-AS1 overexpression maintains the stemness of gastric cancer cells.
Differences between human male and female neutrophils in mRNA, translation efficiency, protein, and phosphoprotein profiles.
A Proximity Complementation Assay to Identify Small Molecules That Enhance the Traffic of ABCA4 Misfolding Variants.
The role of FPR2-mediated ferroptosis in formyl peptide-induced acute lung injury against endothelial barrier damage and protective effect of the mitochondria-derived peptide MOTS-c.
Physalin H ameliorates LPS-induced acute lung injury via KEAP1/NRF2 axis.
SERPINB5 promotes colorectal cancer invasion and migration by promoting EMT and angiogenesis via the TNF-α/NF-κB pathway.
Incorporating Network Pharmacology and Experimental Validation to Identify Bioactive Compounds and Potential Mechanisms of Digitalis in Treating Anaplastic Thyroid Cancer.
Unveiling the therapeutic potential of Dl-3-n-butylphthalide in NTG-induced migraine mouse: activating the Nrf2 pathway to alleviate oxidative stress and neuroinflammation.
Irisin attenuates type 1 diabetic cardiomyopathy by anti-ferroptosis via SIRT1-mediated deacetylation of p53.
EP300-ZNF384 transactivates IL3RA to promote the progression of B-cell acute lymphoblastic leukemia.
6-Gingerol attenuates hepatic ischemia/reperfusion injury through regulating MKP5-mediated P38/JNK pathway.
TRIM56-mediated production of type I interferon inhibits intracellular replication of Rickettsia rickettsii.
Inhibition of SARS-CoV-2 replication by a ssDNA aptamer targeting the nucleocapsid protein.
ACSL4 accelerates osteosarcoma progression via modulating TGF-β/Smad2 signaling pathway.
TDP-43 deficiency in suprachiasmatic nucleus perturbs rhythmicity of neuroactivity in prefrontal cortex.
Non-random spatial organization of telomeres varies during the cell cycle and requires LAP2 and BAF.
AP39 through AMPK-ULK1-FUNDC1 pathway regulates mitophagy, inhibits pyroptosis, and improves doxorubicin-induced myocardial fibrosis.
Missing WD40 Repeats in ATG16L1 Delays Canonical Autophagy and Inhibits Noncanonical Autophagy.
Acupuncture Extended the Thrombolysis Window by Suppressing Blood-Brain Barrier Disruption and Regulating Autophagy-Apoptosis Balance after Ischemic Stroke.
Lung cancer cell-intrinsic IL-15 promotes cell migration and sensitizes murine lung tumors to anti-PD-L1 therapy.
RIPK3 deficiency blocks R-2-hydroxyglutarate-induced necroptosis in IDH-mutated AML cells.
Neutrophil Extracellular Traps Regulate Surgical Brain Injury by Activating the cGAS-STING Pathway.
OPA1 mutation affects autophagy and triggers senescence in autosomal dominant optic atrophy plus fibroblasts.
Modulation of peroxisomal import by the PEX13 SH3 domain and a proximal FxxxF binding motif.
Bioactive 3D Electrohydrodynamic Printed Lattice Architectures Augment Tenogenesis of Tendon Stem/Progenitor Cells.
Hepatitis E virus ORF3 protein hijacking thioredoxin domain-containing protein 5 (TXNDC5) for its stability to promote viral particle release.
Lipidomics reveals the significance and mechanism of the cellular ceramide metabolism for rotavirus replication.
TSHR signaling promotes hippocampal dependent memory formation through modulating Wnt5a/β-catenin mediated neurogenesis.
Identification of a novel FOXO3 agonist that protects against alcohol induced liver injury.
Inhibition of autophagy-related protein 7 enhances anti-tumor immune response and improves efficacy of immune checkpoint blockade in microsatellite instability colorectal cancer.
Identification and validation of a lactate metabolism-related six-gene prognostic signature in intrahepatic cholangiocarcinoma.
Construction and validation of a folate metabolism-related gene signature for predicting prognosis in HNSCC.
KDM5C-Mediated Recruitment of BRD4 to Chromatin Regulates Enhancer Activation and BET Inhibitor Sensitivity.
hsa_circ_0007919 promotes pancreatic cancer metastasis by modulating Sp1-mediated THBS1 transcription.
PRMT4 interacts with NCOA4 to inhibit ferritinophagy in cisplatin-induced acute kidney injury.
TDCPP and TiO(2) NPs aggregates synergistically induce SH-SY5Y cell neurotoxicity by excessive mitochondrial fission and mitophagy inhibition.
Mesenchymal Stem Cells-Derived Exosomes Alleviate Acute Lung Injury by Inhibiting Alveolar Macrophage Pyroptosis.
AURKA knockdown inhibits esophageal squamous cell carcinoma progression through ferroptosis.
Butyrate attenuates the stemness of lung cancer cells through lysosome Fe(2+)- and SLC7A11-mediated ferroptosis.
Incorporating machine learning and PPI networks to identify mitochondrial fission-related immune markers in abdominal aortic aneurysms.
Endothelin-1-mediated Brainstem Glial Activation Produces Asthmatic Airway Vagal Hypertonia Via Enhanced ATP-P2X4 Receptor Signaling in Sprague-Dawley Rats.
FBXL8 inhibits post-myocardial infarction cardiac fibrosis by targeting Snail1 for ubiquitin-proteasome degradation.
KYNA Ameliorates Glutamate Toxicity of HAND by Enhancing Glutamate Uptake in A2 Astrocytes.
The Suppression of the Epithelial to Mesenchymal Transition in Prostate Cancer through the Targeting of MYO6 Using MiR-145-5p.
Garlic oil supplementation blocks inflammatory pyroptosis-related acute lung injury by suppressing the NF-κB/NLRP3 signaling pathway via H(2)S generation.
Developing nucleoside tailoring strategies against SARS-CoV-2 via ribonuclease targeting chimera.
CARMA3 Drives NF-κB Activation and Promotes Intervertebral Disc Degeneration: Involvement of CARMA3-BCL10-MALT1 Signalosome.
The Long Noncoding RNA Gall Bladder Cancer-Associated Suppressor of Pyruvate Carboxylase Inhibits the Proliferation, Migration, and Invasion of Colorectal Cancer Cells and Induces Their Apoptosis.
Structural basis for dimerization of a paramyxovirus polymerase complex.
Palmitoylation alters LDHA activity and pancreatic cancer response to chemotherapy.
Cascade-Catalyzed Nanogel for Amplifying Starvation Therapy by Nitric Oxide-Mediated Hypoxia Alleviation.
PRMT1 Sustains De Novo Fatty Acid Synthesis by Methylating PHGDH to Drive Chemoresistance in Triple-Negative Breast Cancer.
Glutaminolysis regulates endometrial fibrosis in intrauterine adhesion via modulating mitochondrial function.
KLF10/CBS increases the sensitivity of gastric carcinoma cells to methionine restriction by promoting sulfur transfer pathway.
Spastin regulates anaphase chromosome separation distance and microtubule-containing nuclear tunnels.
Human gestational diabetes mellitus-derived exosomes impair glucose homeostasis in pregnant mice and stimulate functional maturation of offspring-islets.
Sialylation on vesicular integrin β1 determined endocytic entry of small extracellular vesicles into recipient cells.
Neonatal microglia transplantation at early stage but not late stage after traumatic brain injury shows protective effects in mice.
Paracatalytic induction: Subverting specificity in hedgehog protein autoprocessing with small molecules.
Isolation and Cultivation of Vascular Smooth Muscle Cells from the Mouse Circle of Willis.
SERBP1 Promotes Stress Granule Clearance by Regulating 26S Proteasome Activity and G3BP1 Ubiquitination and Protects Male Germ Cells from Thermostimuli Damage.
Inhibition of LAMP3 mediates the protective effect of vitamin D against hypoxia/reoxygenation in trophoblast cells.
Fucoidan alleviates the hepatorenal syndrome through inhibition organic solute transporter α/β to reduce bile acids reabsorption.
Rapamycin attenuates pyroptosis by suppressing mTOR phosphorylation and promoting autophagy in LPS-induced bronchopulmonary dysplasia.
Identification of PDK4 as Hub Gene for Diabetic Nephropathy Using Co-Expression Network Analysis.
Functional enhancement of acute infracted heart by coinjection of autologous adipose-derived stem cells with matrigel.
ELK3 Targeting AEG1 Promotes Migration and Invasion of Ovarian Cancer Cells under Hypoxia.
Tilianin Protects against Nonalcoholic Fatty Liver Disease in Early Obesity Mice.
LncRNA AK001796 promotes cell proliferation via acting as a ceRNA of miR-150 in hepatocellular carcinoma.
GLIS Family Zinc Finger 3 Promotes Triple-Negative Breast Cancer Progression by Inducing Cell Proliferation, Migration and Invasion, and Activating the NF-κB Signaling Pathway.
Tumor-Promoting Properties of TMEM9A in Breast Cancer Progression via Activating the Wnt/β-Catenin Signaling Pathway.
Penehyclidine Hydrochloride Protects Rat Cardiomyocytes from Ischemia- Reperfusion Injury by Platelet-derived Growth Factor-B.
Featured interactome of homocysteine-inducible endoplasmic reticulum protein uncovers novel binding partners in response to ER stress.
GAPDH: A common housekeeping gene with an oncogenic role in pan-cancer.
Drug repurposing screens to identify potential drugs for chronic kidney disease by targeting prostaglandin E2 receptor.
Rational design, synthesis and structural characterization of peptides and peptidomimetics to target Hsp90/Cdc37 interaction for treating hepatocellular carcinoma.
Identification of potential diagnostic and prognostic biomarkers for sepsis based on machine learning.
Identification of Potential Biomarkers of Septic Shock Based on Pathway and Transcriptome Analyses of Immune-Related Genes.
Penfluroidol Attenuates the Imbalance of the Inflammatory Response by Repressing the Activation of the NLRP3 Inflammasome and Reduces Oxidative Stress via the Nrf2/HO-1 Signaling Pathway in LPS-Induced Macrophages.
High Expression of DLGAP5 Indicates Poor Prognosis and Immunotherapy in Lung Adenocarcinoma and Promotes Proliferation through Regulation of the Cell Cycle.
Ginkgolide B Blocks Vascular Remodeling after Vascular Injury via Regulating Tgfβ1/Smad Signaling Pathway.
Transcription Factor E2F1 Regulates the Expression of ADRB2.
Fisetin Prevents Angiogenesis in Diabetic Retinopathy by Downregulating VEGF.
AdipoRon Engages Microglia to Antinociception through the AdipoR1/AMPK Pathway in SNI Mice.
NF-κB Inhibitor Myrislignan Induces Ferroptosis of Glioblastoma Cells via Regulating Epithelial-Mesenchymal Transformation in a Slug-Dependent Manner.
Mechanism of Xiezhuo Huayu Yiqi Tongluo Formula in the Treatment of Uric Acid Nephropathy Based on Network Pharmacology, Molecular Docking, and In Vivo Experiments.
JFD, a Novel Natural Inhibitor of Keap1 Alkylation, Suppresses Intracellular Mycobacterium Tuberculosis Growth through Keap1/Nrf2/SOD2-Mediated ROS Accumulation.
Mini-αA Upregulates the miR-155-5p Target Gene CDK2 and Plays an Antiapoptotic Role in Retinal Pigment Epithelial Cells during Oxidative Stress.
Tumor Necrosis Factor-α Promotes the Tumorigenesis, Lymphangiogenesis, and Lymphatic Metastasis in Cervical Cancer via Activating VEGFC-Mediated AKT and ERK Pathways.
Transcutaneous Electrical Nerve Stimulation (TENS) Alleviates Brain Ischemic Injury by Regulating Neuronal Oxidative Stress, Pyroptosis, and Mitophagy.
The Interaction of Apelin and FGFR1 Ameliorated the Kidney Fibrosis through Suppression of TGFβ-Induced Endothelial-to-Mesenchymal Transition.
The Upregulation of GSTO2 is Associated with Colon Cancer Progression and a Poor Prognosis.
Downregulation of VRK1 Inhibits Progression of Lung Squamous Cell Carcinoma through DNA Damage.
Hemoglobin Derived from Subarachnoid Hemorrhage-Induced Pyroptosis of Neural Stem Cells via ROS/NLRP3/GSDMD Pathway.
Silencing MYOT Expression May Inhibit Autophagy in Human Skeletal Muscle Cells.
Bone Mesenchymal Stem Cell-Derived Small Extracellular Vesicles Ameliorated Lipopolysaccharide-Induced Lung Injury Via the miR-21-5p/PCSK6 Pathway.
The Microbiota-Dependent Treatment of Wuzhuyu Decoction for Chronic Migraine Model Rat Associated with Anxiety-Depression Like Behavior.
miR-1 Inhibits the Ferroptosis of Chondrocyte by Targeting CX43 and Alleviates Osteoarthritis Progression.
Long Noncoding RNA LINC00578 Inhibits Ferroptosis in Pancreatic Cancer via Regulating SLC7A11 Ubiquitination.
Aldolase A Promotes Colorectal Cancer Progression through Targeting COPS6 and Regulating MAPK Signaling Pathway.
Metformin Ameliorates D-Galactose-Induced Senescent Human Bone Marrow-Derived Mesenchymal Stem Cells by Enhancing Autophagy.
Resveratrol Suppresses Bupivacaine-Induced Spinal Neurotoxicity in Rats by Inhibiting Endoplasmic Reticulum Stress via SIRT1 Modulation.
Melatonin Ameliorates Ovarian Hyperstimulation Syndrome (OHSS) through SESN2 Regulated Antiapoptosis.
APEX2-Mediated Proximity Labeling of Wnt Receptor Interactors Upon Pathway Activation.
NAT10-mediated RNA acetylation enhances HNRNPUL1 mRNA stability to contribute cervical cancer progression.
Integrated analysis of FKBP1A/SLC3A2 axis in everolimus inducing ferroptosis of breast cancer and anti-proliferation of T lymphocyte.
ZNF460-regulated COMMD7 Promotes Acute Myeloid Leukemia Proliferation Via the NF-κB Signaling Pathway.
Activating SIRT1 deacetylates NF-κB p65 to alleviate liver inflammation and fibrosis via inhibiting NLRP3 pathway in macrophages.
Upregulated desmin/integrin β1/MAPK axis promotes elastic cartilage regeneration with increased ECM mechanical strength.
Inhibition of JNK/c-Jun-ATF2 Overcomes Cisplatin Resistance in Liver Cancer through down-Regulating Galectin-1.
NLRP3 Inflammasome Mediates Silica-induced Lung Epithelial Injury and Aberrant Regeneration in Lung Stem/Progenitor Cell-derived Organotypic Models.
Parkin increases the risk of colitis by downregulation of VDR via autophagy-lysosome degradation.
IGF2BP3 Regulates TMA7-mediated Autophagy and Cisplatin Resistance in Laryngeal Cancer via m6A RNA Methylation.
The FGFR1 Signaling Pathway Upregulates the Oncogenic Transcription Factor FOXQ1 to Promote Breast Cancer Cell Growth.
Upregulation of LRRC8A by m(5)C modification-mediated mRNA stability suppresses apoptosis and facilitates tumorigenesis in cervical cancer.
FGF2 Alleviates Microvascular Ischemia-Reperfusion Injury by KLF2-mediated Ferroptosis Inhibition and Antioxidant Responses.
FOXO3 regulates Smad3 and Smad7 through SPON1 circular RNA to inhibit idiopathic pulmonary fibrosis.
BST2 induced macrophage M2 polarization to promote the progression of colorectal cancer.
TGFβ Governs the Pleiotropic Activity of NDRG1 in Triple-Negative Breast Cancer Progression.
NOP2/Sun RNA methyltransferase 2 is a potential pan-cancer prognostic biomarker and is related to immunity.
Suppression of migration and invasion by taraxerol in the triple-negative breast cancer cell line MDA-MB-231 via the ERK/Slug axis.
USP4 promotes the proliferation and glucose metabolism of gastric cancer cells by upregulating PKM2.
Ketogenic diet ameliorates attention deficit hyperactivity disorder in rats via regulating gut microbiota.
Caffeic acid phenethyl ester suppresses metastasis of breast cancer cells by inactivating FGFR1 via MD2.
Deficient AMPK activity contributes to hyperexcitability in peripheral nociceptive sensory neurons and thermal hyperalgesia in lupus mice.
Exosome-delivered circRPS5 inhibits the progression of melanoma via regulating the miR-151a/NPTX1 axis.
Peptide encoded by lncRNA BVES-AS1 promotes cell viability, migration, and invasion in colorectal cancer cells via the SRC/mTOR signaling pathway.
FAK downregulation suppresses stem-like properties and migration of human colorectal cancer cells.
Inhibition of mycobacteria proliferation in macrophages by low cisplatin concentration through phosphorylated p53-related apoptosis pathway.
miR-192 inhibits the activation of hepatic stellate cells by targeting Rictor.
WTAP affects intracranial aneurysm progression by regulating m6A methylation modification.
miR-199a-5p inhibits aortic valve calcification by targeting ATF6 and GRP78 in valve interstitial cells.
Alkbh5 plays indispensable roles in maintaining self-renewal of hematopoietic stem cells.
HDAC5-mediated PRAME regulates the proliferation, migration, invasion, and EMT of laryngeal squamous cell carcinoma via the PI3K/AKT/mTOR signaling pathway.
Pharmacological inhibition of the ubiquitin-specific protease 8 effectively suppresses glioblastoma cell growth.
Effect of the Lipoxin Receptor Agonist BML-111 on Cigarette Smoke Extract-Induced Macrophage Polarization and Inflammation in RAW264.7 Cells.
Osteoblasts-Derived Exosomal lncRNA-MALAT1 Promotes Osteoclastogenesis by Targeting the miR-124/NFATc1 Signaling Axis in Bone Marrow-Derived Macrophages.
Nanocurcumin Reduces High Glucose and Particulate Matter-Induced Endothelial Inflammation: Mitochondrial Function and Involvement of miR-221/222.
Multifunctional Lithium-Doped Mesoporous Nanoparticles for Effective Dentin Regeneration in vivo.
Osteoclast-Derived Exosomal miR-5134-5p Interferes with Alveolar Bone Homeostasis by Targeting the JAK2/STAT3 Axis.
Exosome-Delivered circSTAU2 Inhibits the Progression of Gastric Cancer by Targeting the miR-589/CAPZA1 Axis.
Dexmedetomidine Ameliorates Cardiac Ischemia/Reperfusion Injury by Enhancing Autophagy Through Activation of the AMPK/SIRT3 Pathway.
Luteolin Alleviates Liver Fibrosis in Rat Hepatic Stellate Cell HSC-T6: A Proteomic Analysis.
The Protective Effect of Selenium Nanoparticles in Osteoarthritis: In vitro and in vivo Studies.
Identification of immune-related biomarkers in peripheral blood of schizophrenia using bioinformatic methods and machine learning algorithms.
Liuwei Dihuang formula ameliorates chronic stress-induced emotional and cognitive impairments in mice by elevating hippocampal O-GlcNAc modification.
The SIK1/CRTC2/CREB1 and TWIST1/PI3K/Akt/GSK3β signaling pathways mediated by microRNA-25-3p are altered in the schizophrenic rat brain.
Comparison of extruded cell nanovesicles and exosomes in their molecular cargos and regenerative potentials.
Acupuncture Relieves Cervical Spondylosis Radiculopathy by Regulating Spinal Microglia Activation Through MAPK Signaling Pathway in Rats.
NEK6 Promotes the Progression of Osteosarcoma Through Activating STAT3 Signaling Pathway by Down-Regulation of miR-26a-5p.
Deep Sea Water Inhibited Pancreatic β-Cell Apoptosis and Regulated Glucose Homeostasis by Affecting Lipid Metabolism in Db/Db Mice.
The Allelic Expression of RNA Editing Gene ADARB1 in Hepatocellular Carcinoma Treated with Transarterial Chemoembolization.
Identification of Critical Biomarkers and Mechanisms of Fructus Ligustri Lucidi on Vitiligo Using Integrated Bioinformatics Analysis.
Transmission of Exosomal TPX2 Promotes Metastasis and Resistance of NSCLC Cells to Docetaxel.
circHECTD1 Promotes the Proliferation and Migration of Human Brain Vascular Smooth Muscle Cells via Interacting with KHDRBS3 to Stabilize EZH2 mRNA Expression.
Chemokine receptor CXCR2 in primary sensory neurons of trigeminal ganglion mediates orofacial itch.
Cardiolipin externalization mediates prion protein (PrP) peptide 106-126-associated mitophagy and mitochondrial dysfunction.
Ectopic expression of Nav1.7 in spinal dorsal horn neurons induced by NGF contributes to neuropathic pain in a mouse spinal cord injury model.
Spinal cannabinoid receptor 2 activation alleviates neuropathic pain by regulating microglia and suppressing P2X7 receptor.
Increasing autophagy ameliorates all-trans-retinal-activated NLRP3 inflammasomes in human THP-1 macrophages.
Mesenchymal stem cell-derived exosomes ameliorate TGF-β1-induced endometrial fibrosis by altering their miRNA profile.
Vitamin D Receptor Activation Targets ROS-Mediated Crosstalk Between Autophagy and Apoptosis in Hepatocytes in Cholestasic Mice.
The mechanism of chemokine receptor ACKR2 in cognitive impairment in young rats with traumatic brain injury.
TREM2 as an independent predictor of poor prognosis promotes the migration via the PI3K/AKT axis in prostate cancer.
Mannan-Binding Lectin Reduces Epithelial-Mesenchymal Transition in Pulmonary Fibrosis via Inactivating the Store-Operated Calcium Entry Machinery.
CD24 May Serve as an Immunotherapy Target in Triple-Negative Breast Cancer by Regulating the Expression of PD-L1.
CCL5 promotes LFA-1 expression in Th17 cells and induces LCK and ZAP70 activation in a mouse model of Parkinson's disease.
The γ-Adducin 1-357 fragment promotes tau pathology.
CC-115 Mediates GSDME-Dependent Pyroptosis in Lung Adenocarcinoma Through the Akt/Bax Pathway.
CRTC2 promotes paclitaxel resistance by inducing autophagy in ovarian cancer in part via the PI3K-AKT signaling axis.
Role of DEP domain-containing protein 1B (DEPDC1B) in epithelial ovarian cancer.
Construction of the metabolism-related models for predicting prognosis and infiltrating immune phenotype in lung squamous cell carcinoma.
Ablation of the GDP-fucose transporter suppresses lung cancer cell proliferation and migration by reducing expression of PD-L1.
PRMT7 Inhibits the Proliferation and Migration of Gastric Cancer Cells by Suppressing the PI3K/AKT Pathway via PTEN.
Identification and characterization of a new variation in DPM2 gene in two Chinese siblings with mild intellectual impairment.
Bacteroides acidifaciens and its derived extracellular vesicles improve DSS-induced colitis.
Prognostic biomarker DARS2 correlated with immune infiltrates in bladder tumor.
FANCI serve as a prognostic biomarker correlated with immune infiltrates in skin cutaneous melanoma.
Central and peripheral analgesic active components of triterpenoid saponins from Stauntonia chinensis and their action mechanism.
Exploring the immune microenvironment of osteosarcoma through T cell exhaustion-associated gene expression: a study on prognosis prediction.
Sigma-1 receptor knockout disturbs gut microbiota, remodels serum metabolome, and exacerbates isoprenaline-induced heart failure.
Exploring the mechanism of aloe-emodin in the treatment of liver cancer through network pharmacology and cell experiments.
The G285S mutation in nsP1 is sufficient to render Sindbis virus as a stable vector for gene delivery.
Induction of RIPK3/MLKL-mediated necroptosis by Erigeron breviscapus injection exhibits potent antitumor effect.
Identification of molecular subtypes based on PANoptosis-related genes and construction of a signature for predicting the prognosis and response to immunotherapy response in hepatocellular carcinoma.
Swine acute diarrhoea syndrome coronavirus (SADS-CoV) Nsp5 antagonizes type I interferon signaling by cleaving DCP1A.
Cryptotanshinone affects HFL-1 cells proliferation by inhibiting cytokines secretion in RAW264.7 cells and ameliorates inflammation and fibrosis in newborn rats with hyperoxia induced lung injury.
Electroacupuncture alleviates ulcerative colitis by targeting CXCL1: evidence from the transcriptome and validation.
A high-concentrate diet induces inflammatory injury via regulating Ca(2+)/CaMKKβ-mediated autophagy in mammary gland tissue of dairy cows.
ANGPTL2+cancer-associated fibroblasts and SPP1+macrophages are metastasis accelerators of colorectal cancer.
Cholesterol 25-hydroxylase suppresses avian reovirus replication by its enzymatic product 25-hydroxycholesterol.
Ferroptosis and its potential role in gestational diabetes mellitus: updated evidence from pathogenesis to therapy.
Identification of afatinib-associated ADH1B and potential small-molecule drugs targeting ADH1B for hepatocellular carcinoma.
Jianpi Yangzheng Xiaozheng decoction alleviates gastric cancer progression via suppressing exosomal PD-L1.
Bicyclol attenuates high fat diet-induced non-alcoholic fatty liver disease/non-alcoholic steatohepatitis through modulating multiple pathways in mice.
Exploration of epithelial-mesenchymal transition-related lncRNA signature and drug sensitivity in breast cancer.
Circulating sepsis-related metabolite sphinganine could protect against intestinal damage during sepsis.
A non-invasive strategy for suppressing asthmatic airway inflammation and remodeling: Inhalation of nebulized hypoxic hUCMSC-derived extracellular vesicles.
Doxorubicin resistance in breast cancer is mediated via the activation of FABP5/PPARγ and CaMKII signaling pathway.
Xue-Jie-San restricts ferroptosis in Crohn's disease via inhibiting FGL1/NF-κB/STAT3 positive feedback loop.
VPA improves ferroptosis in tubular epithelial cells after cisplatin-induced acute kidney injury.
Chebulagic acid suppresses gastric cancer by inhibiting the AURKA/β-catenin/Wnt pathway.
Targeting NK-1R attenuates renal fibrosis via modulating inflammatory responses and cell fate in chronic kidney disease.
Arctiin-encapsulated DSPE-PEG bubble-like nanoparticles inhibit alveolar epithelial type 2 cell senescence to alleviate pulmonary fibrosis via the p38/p53/p21 pathway.
Effects of frog skin peptide temporin-1CEa and its analogs on ox-LDL induced macrophage-derived foam cells.
Integrating RNA-seq and scRNA-seq to explore the mechanism of macrophage ferroptosis associated with COPD.
Yue-bi-tang attenuates adriamycin-induced nephropathy edema through decreasing renal microvascular permeability via inhibition of the Cav-1/ eNOS pathway.
Alleviation of DSS-induced colitis in mice by a new-isolated Lactobacillus acidophilus C4.
Eugenol modulates the NOD1-NF-κB signaling pathway via targeting NF-κB protein in triple-negative breast cancer cells.
The prognostic and immune significance of C15orf48 in pan-cancer and its relationship with proliferation and apoptosis of thyroid carcinoma.
Establishment of sheep nasal mucosa explant model and its application in antiviral research.
The reduced SCFA-producing gut microbes are involved in the inflammatory activation in Kawasaki disease.
Cinnamomi ramulus inhibits cancer cells growth by inducing G2/M arrest.
Acacetin exerts antitumor effects on gastric cancer by targeting EGFR.
Protective effects of Scutellariae Radix Carbonisata-derived carbon dots on blood-heat and hemorrhage rats.
Increased expression of cell adhesion molecules in myofasciitis.
Ethyl-acetate fraction from a cinnamon-cortex extract protects pancreatic β-cells from oxidative stress damage.
C1QC is a prognostic biomarker with immune-related value in kidney renal clear cell carcinoma.
Prognostic value of autophagy-related genes based on single-cell RNA-sequencing in colorectal cancer.
GPR30-mediated non-classic estrogen pathway in mast cells participates in endometriosis pain via the production of FGF2.
Aqueous extract of Amydrium sinense (Engl.) H. Li alleviates hepatic fibrosis by suppressing hepatic stellate cell activation through inhibiting Stat3 signaling.
Lanatoside C decelerates proliferation and induces apoptosis through inhibition of STAT3 and ROS-mediated mitochondrial membrane potential transformation in cholangiocarcinoma.
Identification of gene signatures associated with ulcerative colitis and the association with immune infiltrates in colon cancer.
Chitosan oligosaccharide improves ovarian granulosa cells inflammation and oxidative stress in patients with polycystic ovary syndrome.
Reward enhances resilience to chronic social defeat stress in mice: Neural ECs and mGluR5 mechanism via neuroprotection in VTA and DRN.
Exploring the molecular mechanism of Gan Shuang granules for the treatment of non-alcoholic steatohepatitis using network pharmacology, molecular docking, and experimental verification.
Exercise training-attenuated insulin resistance and liver injury in elderly pre-diabetic patients correlates with NLRP3 inflammasome.
Cinobufacini injection suppresses the proliferation of human osteosarcoma cells by inhibiting PIN1-YAP/TAZ signaling pathway.
Orf virus DNA prime-protein boost strategy is superior to adenovirus-based vaccination in mice and sheep.
Chronic intermittent hypobaric hypoxia ameliorates osteoporosis after spinal cord injury through balancing osteoblast and osteoclast activities in rats.
The prognostic value of the GPAT/AGPAT gene family in hepatocellular carcinoma and its role in the tumor immune microenvironment.
Incorporation of a TGF-β2-inhibiting oligodeoxynucleotide molecular adjuvant into a tumor cell lysate vaccine to enhance antiglioma immunity in mice.
PF-429242 exhibits anticancer activity in hepatocellular carcinoma cells via FOXO1-dependent autophagic cell death and IGFBP1-dependent anti-survival signaling.
Bioinformatics analysis and experimental validation identified HMGA2/microRNA-200c-3p/LSAMP/Wnt axis as an immunological factor of patients with colorectal cancer.
Carcinogen-induced super-enhancer RNA promotes nasopharyngeal carcinoma metastasis through NPM1/c-Myc/NDRG1 axis.
Yin Yang 1 suppresses tumor invasion and metastasis in nasopharyngeal carcinoma by negatively regulating eIF4E transcriptional activity and expression.
hsa_circ_0000519 promotes the progression of lung adenocarcinoma through the hsa-miR-1296-5p/DARS axis.
Mettl3 synergistically regulates TGF-β/SMAD2/3 to promote proliferation and metastasis of gastric cancer.
HSP105 suppresses the progression of cutaneous squamous cell carcinoma by activating the P53 signaling pathway.
Lactate-mediated Fascin protrusions promote cell adhesion and migration in cervical cancer.
Gαi1/3 mediate Netrin-1-CD146-activated signaling and angiogenesis.
Tumor-derived Immunoglobulin-like transcript 4 facilitates angiogenesis of colorectal cancer.
FN1 mRNA 3'-UTR supersedes traditional fibronectin 1 in facilitating the invasion and metastasis of gastric cancer through the FN1 3'-UTR-let-7i-5p-THBS1 axis.
Targeted elimination of senescent cells by engineered extracellular vesicles attenuates atherosclerosis in ApoE(-/-) mice with minimal side effects.
Exosomal transfer leads to chemoresistance through oxidative phosphorylation-mediated stemness phenotype in colorectal cancer.
Application of Lung-Targeted Lipid Nanoparticle-delivered mRNA of soluble PD-L1 via SORT Technology in Acute Respiratory Distress Syndrome.
E3 ubiquitin ligase TRIM21 targets TIF1γ to regulate β-catenin signaling in glioblastoma.
TRPM2 protects against cisplatin-induced acute kidney injury and mitochondrial dysfunction via modulating autophagy.
GPX3 expression was down-regulated but positively correlated with poor outcome in human cancers.
Red recombination enables a wide variety of markerless manipulation of porcine epidemic diarrhea virus genome to generate recombinant virus.
Tripterygium glycosides sensitizes cisplatin chemotherapeutic potency by modulating gut microbiota in epithelial ovarian cancer.
Mechanism of action of icaritin on uterine corpus endometrial carcinoma based on network pharmacology and experimental evaluation.
Tocilizumab (monoclonal anti-IL-6R antibody) reverses anlotinib resistance in osteosarcoma.
Determining the mechanism of pulsatilla decoction for treating gastric cancer: a network pharmacology-based study.
The deubiquitinating enzyme MINDY2 promotes pancreatic cancer proliferation and metastasis by stabilizing ACTN4 expression and activating the PI3K/AKT/mTOR signaling pathway.
PFDN2 promotes cell cycle progression via the hnRNPD-MYBL2 axis in gastric cancer.
Identification of novel molecular subtypes and a signature to predict prognosis and therapeutic response based on cuproptosis-related genes in prostate cancer.
The role of BHLHE40 in clinical features and prognosis value of PDAC by comprehensive analysis and in vitro validation.
Identification and validation of m6A-GPI signatures as a novel prognostic model for colorectal cancer.
Schistosoma japonicum-derived peptide SJMHE1 ameliorates allergic symptoms and responses in mice with allergic rhinitis.
Identification and verification of the temozolomide resistance feature gene DACH1 in gliomas.
Notch4 participates in mesenchymal stem cell-induced differentiation in 3D-printed matrix and is implicated in eccrine sweat gland morphogenesis.
Identification and validation of prognostic and tumor microenvironment characteristics of necroptosis index and BIRC3 in clear cell renal cell carcinoma.
Head and neck squamous cell carcinoma-specific prognostic signature and drug sensitive subtypes based on programmed cell death-related genes.
RBM25 binds to and regulates alternative splicing levels of Slc38a9, Csf1, and Coro6 to affect immune and inflammatory processes in H9c2 cells.
YAP1 affects the prognosis through the regulation of stemness in endometrial cancer.
EXOSC10 is a novel hepatocellular carcinoma prognostic biomarker: a comprehensive bioinformatics analysis and experiment verification.
RNA N6-methyladenosine reader IGF2BP3 promotes acute myeloid leukemia progression by controlling stabilization of EPOR mRNA.
Adrenal SGLT1 or SGLT2 as predictors of atherosclerosis under chronic stress based on a computer algorithm.
Bone marrow mesenchymal stem cell-derived exosomes protect podocytes from HBx-induced ferroptosis.
Transcriptomics reveals the effects of NTRK1 on endoplasmic reticulum stress response-associated genes in human neuronal cell lines.
Sterol regulatory element binding transcription factor 1 promotes proliferation and migration in head and neck squamous cell carcinoma.
METTL3-mediated m6A modification of has_circ_0007905 promotes age-related cataract progression through miR-6749-3p/EIF4EBP1.
Antimicrobial peptide-modified AIE visual composite wound dressing for promoting rapid healing of infected wounds.
S-propargyl-cysteine promotes the stability of atherosclerotic plaque via maintaining vascular muscle contractile phenotype.
Chlorpromazine affects autophagy in association with altered Rag GTPase-mTORC1-TFEB signaling.
Tanshinone IIA inhibits cardiomyocyte pyroptosis through TLR4/NF-κB p65 pathway after acute myocardial infarction.
Novel mutations in PLCZ1 lead to early embryonic arrest as a male factor.
The interplay of common genetic variants NRG1 rs2439302 and RET rs2435357 increases the risk of developing Hirschsprung's disease.
Comprehensive analysis of prognostic value, immune implication and biological function of CPNE1 in clear cell renal cell carcinoma.
Recombinant humanized collagen remodels endometrial immune microenvironment of chronic endometritis through macrophage immunomodulation.
Construction of shared gene signature between rheumatoid arthritis and lung adenocarcinoma helps to predict the prognosis and tumor microenvironment of the LUAD patients.
Effect of Wu Zhi San supplementation in LPS-induced intestinal inflammation and barrier damage in broilers.
The identification of hub-methylated differentially expressed genes in osteoarthritis patients is based on epigenomic and transcriptomic data.
The H protein of attenuated canine distemper virus is degraded via endoplasmic reticulum-associated protein degradation.
Regulation of cellular contractile force, shape and migration of fibroblasts by oncogenes and Histone deacetylase 6.
ALKBH5 inhibitors as a potential treatment strategy in heart failure-inferences from gene expression profiling.
Optimal treatment for post-MI heart failure in rats: dapagliflozin first, adding sacubitril-valsartan 2 weeks later.
Comprehensive analysis to construct a novel immune-related prognostic panel in aging-related gastric cancer based on the lncRNA‒miRNA-mRNA ceRNA network.
Effect of blood flow-restricted resistance training on myocardial fibrosis in early spontaneously hypertensive rats.
Angong niuhuang wan attenuates LPS-induced acute lung injury by inhibiting PIK3CG/p65/MMP9 signaling in mice based on proteomics.
Mir-142-5p inhibits the osteogenic differentiation of bone marrow mesenchymal stem cells by targeting Lhx8.
The m6A reader YTHDC1-mediated lncRNA CTBP1-AS2 m6A modification accelerates cholangiocarcinoma progression.
TESC promotes differentiated thyroid cancer development by activating ERK and weakening NIS and radioiodine uptake.
Protective effect of Platycodon grandiflorus polysaccharide on apoptosis and mitochondrial damage induced by pseudorabies virus in PK-15 cells.
Punicalagin alleviates the hyperproliferation of keratinocytes in psoriasis through inhibiting SKP2 expression.
The RIG-I agonist M8 triggers cell death and natural killer cell activation in human papillomavirus-associated cancer and potentiates cisplatin cytotoxicity.
Generation of a homozygous RANGRF knockout hiPSC line by CRISPR/Cas9 system.
The Clinical Characteristics and Potential Molecular Mechanism of LMNA Mutation-Related Lipodystrophy.
Dietary Apigenin Relieves Body Weight and Glycolipid Metabolic Disturbance via Pro-Browning of White Adipose Mediated by Autophagy Inhibition.
Lactate Improves Long-term Cognitive Impairment Induced By Repeated Neonatal Sevoflurane Exposures Through SIRT1-mediated Regulation of Adult Hippocampal Neurogenesis and Synaptic Plasticity in Male Mice.
IRAK-M Ablation Promotes Status Epilepticus-Induced Neuroinflammation via Activating M1 Microglia and Impairing Excitatory Synaptic Function.
Orally Induced High Serum Level of Trimethylamine N-oxide Worsened Glial Reaction and Neuroinflammation on MPTP-Induced Acute Parkinson's Disease Model Mice.
ACE2-EGFR-MAPK signaling contributes to SARS-CoV-2 infection.
Platelet factor 4 (PF4) induces cluster of differentiation 40 (CD40) expression in human aortic endothelial cells (HAECs) through the SIRT1/NF-κB/p65 signaling pathway.
Inhibition of USP10 induces myeloma cell apoptosis by promoting cyclin D3 degradation.
FBXO28 suppresses liver cancer invasion and metastasis by promoting PKA-dependent SNAI2 degradation.
Klotho-beta attenuates Rab8a-mediated exosome regulation and promotes prostate cancer progression.
Cytological and functional effect of complement 3a on Human Scleral Fibroblasts.
MIR663AHG as a competitive endogenous RNA regulating TGF-β-induced epithelial proliferation and epithelial-mesenchymal transition in benign prostate hyperplasia.
Cuproptosis enhances docetaxel chemosensitivity by inhibiting autophagy via the DLAT/mTOR pathway in prostate cancer.
ASXL3 gene mutations inhibit cell proliferation and promote cell apoptosis in mouse cardiomyocytes by upregulating lncRNA NONMMUT063967.2.
Lysine methylation of PPP1CA by the methyltransferase SUV39H2 disrupts TFEB-dependent autophagy and promotes intervertebral disc degeneration.
ANRIL promotes the regulation of colorectal cancer on lymphatic endothelial cells via VEGF-C and is the key target for Pien Tze Huang to inhibit cancer metastasis.
Saikosaponin A protects against uremic toxin indole‑3 acetic acid‑induced damage to the myocardium.
Hirudin inhibits glioma growth through mTOR-regulated autophagy.
Loss of NSUN6 inhibits osteosarcoma progression by downregulating EEF1A2 expression and activation of Akt/mTOR signaling pathway via m(5)C methylation.
Trans-ε-viniferin as an inhibitor of TMEM16A preventing intestinal smooth muscle contraction.
HDAC6 decreases H4K16 and α-tubulin acetylation during porcine oocyte maturation.
Structure and anti-inflammatory activity of neo-clerodane diterpenoids from Scutellaria barbata.
Elucidation of the mechanism of nuclear localization of Mexican tetra Neu4 via bipartite nuclear localization signal and less conserved regions.
Sulforaphane, an NRF2 agonist, alleviates ferroptosis in acute liver failure by regulating HDAC6 activity.
Excessive Lysosomal Stress Response and Consequently Impaired Autophagy Contribute to Fluoride-Induced Developmental Neurotoxicity.
Alleviative Effect of Threonine on Cadmium-Induced Liver Injury in Mice.
Fecal Microbiota Transplantation from Aged Mice Render Recipient Mice Resistant to MPTP-Induced Nigrostriatal Degeneration Via a Neurogenesis-Dependent but Inflammation-Independent Manner.
Electroacupuncture-Modulated MiR-106b-5p Expression Enhances Autophagy by Targeting Beclin-1 to Promote Motor Function Recovery After Spinal Cord Injury in Rats.
RBMX involves in telomere stability maintenance by regulating TERRA expression.
Phosphorylation of KRT8 (keratin 8) by excessive mechanical load-activated PKN (protein kinase N) impairs autophagosome initiation and contributes to disc degeneration.
TRAF1 improves cisplatin-induced acute kidney injury via inhibition of inflammation and metabolic disorders.
TRIM25-mediated ubiquitination of G3BP1 regulates the proliferation and migration of human neuroblastoma cells.
The adiponectin receptor agonist AdipoAI attenuates periodontitis in diabetic rats by inhibiting gingival fibroblast-induced macrophage migration.
Aerobic exercise enhances mitochondrial homeostasis to counteract D-galactose-induced sarcopenia in zebrafish.
Genetic modification of miR-34a enhances efficacy of transplanted human dental pulp stem cells after ischemic stroke.
miR-181b promotes angiogenesis and neurological function recovery after ischemic stroke.
Serum response factor promotes axon regeneration following spinal cord transection injury.
Hexachlorocyclohexane impairs human sperm motility by affecting lysine glutarylation and mitochondrial functions.
Mitophagy contributes to zinc-induced ferroptosis in porcine testis cells.
The therapeutic effect of Shenhua tablet against mesangial cell proliferation and renal inflammation in mesangial proliferative glomerulonephritis.
DWL-4-140: A allene small molecule targeting STING that alleviates lupus-like phenotype in Trex1(-/-) mice.
Inhibition of autophagy and RIP1/RIP3/MLKL-mediated necroptosis by edaravone attenuates blood spinal cord barrier disruption following spinal cord injury.
Cardioprotective efficacy of Xin-shu-bao tablet in heart failure with reduced ejection fraction by modulating THBD/ARRB1/FGF1/STIM1 signaling.
A novel onco-cardiological mouse model of lung cancer-induced cardiac dysfunction and its application in identifying potential roles of tRNA-derived small RNAs.
Rgl-exomiR-7972, a novel plant exosomal microRNA derived from fresh Rehmanniae Radix, ameliorated lipopolysaccharide-induced acute lung injury and gut dysbiosis.
Sialic Acid Enhanced the Antistress Capability under Challenging Situations by Increasing Synaptic Transmission.
AHR, a novel inhibitory immune checkpoint receptor, is a potential therapeutic target for chemoresistant glioblastoma.
miR-32-5p induces hepatic steatosis and hyperlipidemia by triggering de novo lipogenesis.
Blocking IL-6 signaling improves glucose tolerance via SLC39A5-mediated suppression of glucagon secretion.
Targeting the Hedgehog pathway with novel Gli1 hydrophobic tagging degraders.
Predicting and overcoming resistance to CDK9 inhibitors for cancer therapy.
UBE3A and MCM6 synergistically regulate the proliferation and migration of lung adenocarcinoma cells.
Brain-derived estrogen: a critical player in maintaining cognitive health of aged female rats, possibly involving GPR30.
Celastrol attenuates diabetic nephropathy by upregulating SIRT1-mediated inhibition of EZH2related wnt/β-catenin signaling.
Liensinine pretreatment reduces inflammation, oxidative stress, apoptosis, and autophagy to alleviate sepsis acute kidney injury.
The p65-LOC727924-miR-26a/KPNA3-p65 regulatory loop mediates vasoactive intestinal peptide effects on osteoarthritis chondrocytes.
Ameliorative effects of the Coptis inflorescence extract against lung injury in diabetic mice by regulating AMPK/NEU1 signaling.
Berberine ameliorates iron levels and ferroptosis in the brain of 3 × Tg-AD mice.
Total alkaloids of Fritillaria unibracteata var. wabuensis bulbus ameliorate chronic asthma via the TRPV1/Ca(2+)/NFAT pathway.
Gentianella acuta-derived Gen-miR-1 suppresses myocardial fibrosis by targeting HAX1/HMG20A/Smads axis to attenuate inflammation in cardiac fibroblasts.
Comprehensive analysis of transcriptome-wide N6-methyladenosine methylomes in the Barrett's esophagus in rats.
Zoledronate Promotes Peri-Implant Osteogenesis in Diabetic Osteoporosis by the AMPK Pathway.
KDM2B regulates inflammation and oxidative stress of sepsis via targeting NF-κB and AP-1 pathways.
FOSL2 participates in renal fibrosis via SGK1-mediated epithelial-mesenchymal transition of proximal tubular epithelial cells.
CircNCOR1 regulates breast cancer radiotherapy efficacy by regulating CDK2 via hsa-miR-638 binding.
Disulfiram suppresses epithelial-mesenchymal transition (EMT), migration and invasion in cervical cancer through the HSP90A/NDRG1 pathway.
ADAR1 polymorphisms contribute to increased susceptibility in pediatric acute lymphoblastic leukemia.
miR-146b-5p promotes duck Tembusu virus replication by targeting RPS14.
TP53RK Drives the Progression of Chronic Kidney Disease by Phosphorylating Birc5.
CSNK2A2 promotes hepatocellular carcinoma progression through activation of NF-κB pathway.
Infection by exosome-carried Coxsackievirus B3 induces immune escape resulting in an aggravated pathogenesis.
Novel Long Non-Coding RNA (lncRNA) Transcript AL137782.1 Promotes the Migration of Normal Lung Epithelial Cells through Positively Regulating LMO7.
Vitamin D3 regulates NSUN2 expression and inhibits melanoma cell proliferation and migration.
SENP5 promotes homologous recombination-mediated DNA damage repair in colorectal cancer cells through H2AZ deSUMOylation.
Enhanced therapeutic effect of PEDF-loaded mesenchymal stem cell-derived small extracellular vesicles against oxygen-induced retinopathy through increased stability and penetrability of PEDF.
The DACH1 Gene Transcriptional Activation and Protein Degradation Mediated by Transactivator Tas of Prototype Foamy Virus.
Gut microbes exacerbate systemic inflammation and behavior disorders in neurologic disease CADASIL.
Bone marrow mesenchymal stem cellsderived exosomes stabilize atherosclerosis through inhibiting pyroptosis.
Mature human induced pluripotent stem cell-derived cardiomyocytes promote angiogenesis through alpha-B crystallin.
PI3K/Akt signalling pathway-associated long noncoding RNA signature predicts the prognosis of laryngeal cancer patients.
Interferon inhibits a model RNA virus via a limited set of inducible effector genes.
FBL promotes cancer cell resistance to DNA damage and BRCA1 transcription via YBX1.
UBQLN2 and HSP70 participate in Parkin-mediated mitophagy by facilitating outer mitochondrial membrane rupture.
Phosphorylation of PPDPF via IL6-JAK2 activates the Wnt/β-catenin pathway in colorectal cancer.
Hyodeoxycholic acid ameliorates nonalcoholic fatty liver disease by inhibiting RAN-mediated PPARα nucleus-cytoplasm shuttling.
Activation of G-protein-coupled receptor 183 initiates inflammatory pain via macrophage CCL22 secretion.
Riboflavin ameliorates pathological cardiac hypertrophy and fibrosis through the activation of short-chain acyl-CoA dehydrogenase.
A natural chalcone cardamonin inhibits necroptosis and ameliorates dextran sulfate sodium (DSS)-induced colitis by targeting RIPK1/3 kinases.
Activation of TrkB signaling mitigates cerebellar anomalies caused by Rbm4-Bdnf deficiency.
Lactate modulates iron metabolism by binding soluble adenylyl cyclase.
N6-methyladenosine modification of PLOD2 causes spermatocyte damage in rats with varicocele.
MiR-3653 blocks autophagy to inhibit epithelial-mesenchymal transition in breast cancer cells by targeting the autophagy-regulatory genes ATG12 and AMBRA1.
Targeting of AKT1 by miR-143-3p Suppresses Epithelial-to-Mesenchymal Transition in Prostate Cancer.
Cystathionine β-Synthase Suppresses NLRP3 Inflammasome Activation via Redox Regulation in Microglia.
Characterization of a Human Gastrointestinal Stromal Tumor Cell Line Established by SV40LT-Mediated Immortalization.
Curcumin-Loaded Macrophage-Derived Exosomes Effectively Improve Wound Healing.
Increased DNMT1 Involvement in the Activation of LO2 Cell Death Induced by Silver Nanoparticles via Promoting TFEB-Dependent Autophagy.
Ursolic Acid Alleviates Neuroinflammation after Intracerebral Hemorrhage by Mediating Microglial Pyroptosis via the NF-κB/NLRP3/GSDMD Pathway.
Dihydroorotate dehydrogenase promotes cell proliferation and suppresses cell death in esophageal squamous cell carcinoma and colorectal carcinoma.
The histone deacetylase inhibitor SAHA exerts a protective effect against myocardial ischemia/reperfusion injury by inhibiting sodium-calcium exchanger.
African Swine Fever Virus H240R Protein Inhibits the Production of Type I Interferon through Disrupting the Oligomerization of STING.
Pleckstrin-2 promotes tumour immune escape from NK cells by activating the MT1-MMP-MICA signalling axis in gastric cancer.
HSP90B1-mediated plasma membrane localization of GLUT1 promotes radioresistance of glioblastomas.
Benzophenanthridine Alkaloid Chelerythrine Elicits Necroptosis of Gastric Cancer Cells via Selective Conjugation at the Redox Hyperreactive C-Terminal Sec(498) Residue of Cytosolic Selenoprotein Thioredoxin Reductase.
SQLE Knockdown inhibits bladder cancer progression by regulating the PTEN/AKT/GSK3β signaling pathway through P53.
Fucogalactan Sulfate (FS) from Laminaria japonica Regulates Lipid Metabolism in Diet-Induced Humanized Dyslipidemia Mice via an Intestinal FXR-FGF19-CYP7A1/CYP8B1 Pathway.
Intercellular adhesion molecule 2 as a novel prospective tumor suppressor induced by ERG promotes ubiquitination-mediated radixin degradation to inhibit gastric cancer tumorigenicity and metastasis.
Red Rice Seed Coat Targeting SPHK2 Ameliorated Alcoholic Liver Disease via Restored Intestinal Barrier and Improved Gut Microbiota in Mice.
DKK1 Promotes Epithelial-Mesenchymal Transition and Cisplatin Resistance in Gastric Cancer via Activation of the PI3K/AKT Pathway.
Discovery of Salidroside as a Novel Non-Coding RNA Modulator to Delay Cellular Senescence and Promote BK-Dependent Apoptosis in Cerebrovascular Smooth Muscle Cells of Simulated Microgravity Rats.
Long intergenic non-coding RNA DIO3OS promotes osteosarcoma metastasis via activation of the TGF-β signaling pathway: a potential diagnostic and immunotherapeutic target for osteosarcoma.
Ar-turmerone inhibits the proliferation and mobility of glioma by downregulating cathepsin B.
PARP14 inhibition restores PD-1 immune checkpoint inhibitor response following IFNγ-driven acquired resistance in preclinical cancer models.
Causal ALS genes impact the MHC class II antigen presentation pathway.
Metabolic characteristics of voriconazole - Induced liver injury in rats.
Oryza sativa L. Indica Seed Coat Ameliorated Concanavalin A-Induced Acute Hepatitis in Mice via MDM2/p53 and PKCα/MAPK1 Signaling Pathways.
Genome-wide enhancer-gene regulatory maps link causal variants to target genes underlying human cancer risk.
Repurposing of Ibrutinib and Quizartinib as potent inhibitors of necroptosis.
LncRNA CCAT1 facilitates the progression of gastric cancer via PTBP1-mediated glycolysis enhancement.
RAD51D Secondary Mutation-Mediated Resistance to PARP-Inhibitor-Based Therapy in HGSOC.
Comprehensive Analysis of the Transcriptome-Wide m(6)A Methylome in Shaziling Pig Testicular Development.
Tauopathy promotes spinal cord-dependent production of toxic amyloid-beta in transgenic monkeys.
Activation of CTNNB1 by deubiquitinase UCHL3-mediated stabilization facilitates bladder cancer progression.
FTO-targeted siRNA delivery by MSC-derived exosomes synergistically alleviates dopaminergic neuronal death in Parkinson's disease via m6A-dependent regulation of ATM mRNA.
Depletion of G9A attenuates imiquimod-induced psoriatic dermatitis via targeting EDAR-NF-κB signaling in keratinocyte.
CREB1-driven CXCR4(hi) neutrophils promote skin inflammation in mouse models and human patients.
Mometasone Furoate Inhibits the Progression of Head and Neck Squamous Cell Carcinoma via Regulating Protein Tyrosine Phosphatase Non-Receptor Type 11.
Chronic cough relief by allosteric modulation of P2X3 without taste disturbance.
The Crosstalk between the EGFR and IFN-γ Pathways and Synergistic Roles in Survival Prediction and Immune Escape in Gliomas.
SIRT2 inhibition protects against cardiac hypertrophy and ischemic injury.
Hepatic soluble epoxide hydrolase activity regulates cerebral Aβ metabolism and the pathogenesis of Alzheimer's disease in mice.
Integration of AIEgens into covalent organic frameworks for pyroptosis and ferroptosis primed cancer immunotherapy.
ALDOC promotes non-small cell lung cancer through affecting MYC-mediated UBE2N transcription and regulating Wnt/β-catenin pathway.
Dual single guide RNAs-mediating deletion of mature myostatin peptide results in concomitant muscle fibre hyperplasia and adipocyte hypotrophy in pigs.
LAD1 promotes malignant progression by diminishing ubiquitin-dependent degradation of vimentin in gastric cancer.
Multi-omic analysis of mandibuloacral dysplasia type A patient iPSC-derived MSC senescence reveals miR-311 as a novel biomarker for MSC senescence.
Phenylalanine-tRNA aminoacylation is compromised by ALS/FTD-associated C9orf72 C4G2 repeat RNA.
Sodium hydrosulfide moderately alleviates the hallmark symptoms of Duchenne muscular dystrophy in mdx mice.
Denervation aggravates renal ischemia reperfusion injury via BMAL1-mediated Nrf2/ARE pathway.
Genetic deletion or pharmacological inhibition of soluble epoxide hydrolase attenuated particulate matter 2.5 exposure mediated lung injury.
Piperlonguminine attenuates renal fibrosis by inhibiting TRPC6.
The alcohol extracts of Sceptridium ternatum (Thunb.) Lyon exert anti-pulmonary fibrosis effect through targeting SETDB1/STAT3/p-STAT3 signaling.
Lorazepam Stimulates IL6 Production and Is Associated with Poor Survival Outcomes in Pancreatic Cancer.
Zbtb14 Promotes Non-Alcoholic Fatty Liver Disease-Associated Fibrosis in Gerbils via the β-Catenin Pathway.
Paternal cadmium exposure affects estradiol synthesis by impairing intracellular cholesterol homeostasis and mitochondrial function in offspring female mice.
Seizure enhances SUMOylation and zinc-finger transcriptional repression in neuronal nuclei.
Mitoquinone alleviates osteoarthritis progress by activating the NRF2-Parkin axis.
Biglycan regulated colorectal cancer progress by modulating enteric neuron-derived IL-10 and abundance of Bacteroides thetaiotaomicron.
The RNA-Splicing Ligase RTCB Promotes Influenza A Virus Replication by Suppressing Innate Immunity via Interaction with RNA Helicase DDX1.
Liver X Receptor LXRα Promotes Grass Carp Reovirus Infection by Attenuating IRF3-CBP Interaction and Inhibiting RLR Antiviral Signaling.
Arginine methylation of HSPA8 by PRMT9 inhibits ferroptosis to accelerate hepatitis B virus-associated hepatocellular carcinoma progression.
Systemic gene therapy using an AAV44.9 vector rescues a neonatal lethal mouse model of propionic acidemia.
Catalysis-Mediated Male Contraception through Black Phosphorus Nanosheets.
mTORC1 Regulates the Metabolic Switch of Postnatal Cardiomyocytes During Regeneration.
YBX1 as an oncogenic factor in T-cell acute lymphoblastic leukemia.
Therapeutic inhibition of miR-155 attenuates liver fibrosis via STAT3 signaling.
A Nucleus-Targeting WT1 Antagonistic Peptide Encapsulated in Polymeric Nanomicelles Combats Refractory Chronic Myeloid Leukemia.
A novel recombinant ORF7-siRNA delivered by flexible nano-liposomes inhibits varicella zoster virus infection.
Length limitation of astral microtubules orients cell divisions in murine intestinal crypts.
H3K18 lactylation of senescent microglia potentiates brain aging and Alzheimer's disease through the NFκB signaling pathway.
The lysosome-mitochondrion crosstalk engaged in silver nanoparticles-disturbed mitochondrial homeostasis.
The Exosome-Transmitted lncRNA LOC100132249 Induces Endothelial Dysfunction in Diabetic Retinopathy.
Depleted uranium induces thyroid damage through activation of ER stress via the thrombospondin 1-PERK pathway.
Glibenclamide promotes FGF21 secretion in interscapular BAT and attenuates depression-like behaviors in male mice with HFD-induced obesity.
Gap26 inhibited angiogenesis through the β-catenin-VE-cadherin-VEGFR2-Erk signaling pathway.
Effect of Tamoxifen on Proteome Expression during In Vitro Myogenesis in Murine Skeletal Muscle C(2)C(12) Cells.
Epithelial TIPE1 Protein Guards against Colitis by Inhibiting TNF-α-Mediated Inflammation.
Protein arginine methyltransferase 5 mediates arginine symmetric dimethylation of influenza A virus PB2 and supports viral replication.
Paraquat-induced ferroptosis suppression via NRF2 expression regulation.
Graphene oxide had adverse effects on sperm motility and morphology through oxidative stress.
Knockdown of LINC00702 inhibits the growth and induces apoptosis of breast cancer through the Wnt/β-catenin pathway.
Resveratrol inhibits ferroptosis via activating NRF2/GPX4 pathway in mice with spinal cord injury.
ANKRD22 knockdown suppresses papillary thyroid cell carcinoma growth and migration and modulates the Wnt/β-catenin signaling pathway.
Oxidative stress mediates the inhibitory effects of Manzamine A on uterine leiomyoma cell proliferation and extracellular matrix deposition via SOAT inhibition.
Characterization of SHARPIN knockout Syrian hamsters developed using CRISPR/Cas9 system.
Rutaecarpine ameliorates osteoarthritis by inhibiting PI3K/AKT/NF‑κB and MAPK signalling transduction through integrin αVβ3.
MBNL1‑AS1 attenuates tumor cell proliferation by regulating the miR‑29c‑3p/BVES signal in colorectal cancer.
Interleukin-22 Inhibits Apoptosis of Gingival Epithelial Cells Through TGF-β Signaling Pathway During Periodontitis.
Dysregulation of iron homeostasis by TfR-1 renders EZH2 wild type diffuse large B-cell lymphoma resistance to EZH2 inhibition.
Chronic β-adrenergic stress contributes to cardiomyopathy in rodents with collagen-induced arthritis.
A novel small-molecular CCR5 antagonist promotes neural repair after stroke.
Pingxiao capsule inhibits lung metastasis of triple-negative breast cancer and sensitizes breast cancer to radiotherapy.
Circular RNA EIF3I promotes papillary thyroid cancer progression by interacting with AUF1 to increase Cyclin D1 production.
Oncogenic BRAF noncanonically promotes tumor metastasis by mediating VASP phosphorylation and filopodia formation.
Upregulation by duloxetine of the transforming growth factor-α-induced migration of hepatocellular carcinoma cells via enhancement of the c-Jun N-terminal kinase activity.
Differential traits between microvesicles and exosomes in enterovirus infection.
SEMA3B-AS1 suppresses colorectal carcinoma progression by inhibiting Semaphorin 3B-dependent VEGF signaling pathway activation.
Kif15 deficiency contributes to depression-like behavior in mice.
Autophagy induced by human adenovirus B7 structural protein VI inhibits viral replication.
HBV precore G1896A mutation promotes growth of hepatocellular carcinoma cells by activating ERK/MAPK pathway.
METTL3-mediated m6A modification of pri-miR-148a-3p affects prostate cancer progression by regulating TXNIP.
Lens epithelial cell-derived exosome inhibits angiogenesis in ocular pathological neovascularization through its delivery of miR-146a-5p.
Hypomethylation of CD3D promoter induces immune cell infiltration and supports malignant phenotypes in uveal melanoma.
NPLC0393 from Gynostemma pentaphyllum ameliorates Alzheimer's disease-like pathology in mice by targeting protein phosphatase magnesium-dependent 1A phosphatase.
Cryptotanshinone alleviates radiation-induced lung fibrosis via modulation of gut microbiota and bile acid metabolism.
Paternal cadmium exposure induces glucolipid metabolic reprogramming in offspring mice via PPAR signaling pathway.
BCKDHA contributes to melanoma progression by promoting the expressions of lipogenic enzymes FASN and ACLY.
Long-term and liver-selected ginsenoside C-K nanoparticles retard NAFLD progression by restoring lipid homeostasis.
TRAP1 inhibits MARCH5-mediated MIC60 degradation to alleviate mitochondrial dysfunction and apoptosis of cardiomyocytes under diabetic conditions.
The E3 ubiquitin ligase TRIM17 promotes gastric cancer survival and progression via controlling BAX stability and antagonizing apoptosis.
Multiple sevoflurane exposures during mid-trimester induce neurotoxicity in the developing brain initiated by 15LO2-Mediated ferroptosis.
Treponema pallidum membrane protein Tp47 induced autophagy and inhibited cell migration in HMC3 cells via the PI3K/AKT/FOXO1 pathway.
Oxytocin Receptor in Cerebellar Purkinje Cells Does Not Engage in Autism-Related Behaviors.
Depleting ANTXR1 suppresses glioma growth via deactivating PI3K/AKT pathway.
Cooperative effects of SIRT1 and SIRT2 on APP acetylation.
Oxidative stress and inflammation are mediated via aryl hydrocarbon receptor signalling in idiopathic membranous nephropathy.
Glycogen synthase kinase 3 controls T-cell exhaustion by regulating NFAT activation.
Aquaporin-7 Facilitates Proliferation and Adipogenic Differentiation of Mouse Bone Marrow Mesenchymal Stem Cells by Regulating Hydrogen Peroxide Transport.
NMDA receptor activation induces damage of alveolar type II cells and lung fibrogenesis through ferroptosis.
N-glycosylation by N-acetylglucosaminyltransferase IVa enhances the interaction of integrin β1 with vimentin and promotes hepatocellular carcinoma cell motility.
Streptococcus uberis induced expressions of pro-inflammatory IL-6, TNF-α, and IFN-γ in bovine mammary epithelial cells associated with inhibited autophagy and autophagy flux formation.
Deoxynivalenol induces endoplasmic reticulum stress-associated apoptosis via the IRE1/JNK/CHOP pathway in porcine alveolar macrophage 3D4/21 cells.
Eph receptor A4 regulates motor neuron ferroptosis in spinal cord ischemia/reperfusion injury in rats.
M2 macrophages mediate fibrotic scar formation in the early stages after cerebral ischemia in rats.
Body Weight Support Treadmill Training Combined With Sciatic Nerve Electrical Stimulation Ameliorating Motor Function by Enhancing PI3K/Akt Proteins Expression via BDNF/TrkB Signaling Pathway in Rats with Spinal Cord Injury.
Ootheca mantidis mitigates renal fibrosis in mice by the suppression of apoptosis via increasing the gut microbe Akkermansia muciniphila and modulating glutamine metabolism.
Atorvastatin rescues vascular endothelial injury in hypertension by WWP2-mediated ubiquitination and degradation of ATP5A.
CircABPD1 alleviates oxidative lung injury of bronchopulmonary dysplasia through regulating miR-330-3p/HIF1α axis.
Knockdown of Mmu-circ-0001380 Attenuates Myocardial Ischemia/Reperfusion Injury via Modulating miR-106b-5p/Phlpp2 Axis.
Quercetin attenuates avermectin-induced cardiac injury in carp through inflammation, oxidative stress, apoptosis and autophagy.
Design, synthesis and biological evaluation of novel modified dual-target shikonin derivatives for colorectal cancer treatment.
Parkin regulates IGF2BP3 through ubiquitination in the tumourigenesis of cervical cancer.
KCTD4 interacts with CLIC1 to disrupt calcium homeostasis and promote metastasis in esophageal cancer.
Monoclonal antibody targeting mu-opioid receptor attenuates morphine tolerance via enhancing morphine-induced receptor endocytosis.
Equine β-defensin 1 regulates cytokine expression and phagocytosis in S. aureus-infected mouse monocyte macrophages via the Paxillin-FAK-PI3K pathway.
Autophagy induced by PP121 alleviates MSU crystal-induced acute gouty arthritis via inhibition of the NLRP3 inflammasome.
Mitochonic acid 5 rescues cardiomyocytes from doxorubicin-induced toxicity via repressing the TNF-α/NF-κB/NLRP3-mediated pyroptosis.
HMGB1 induces macrophage pyroptosis in chronic endometritis.
Baicalein enhances immune response in TNBC by inhibiting leptin expression of adipocytes.
The PRX-1/TLR4 axis promotes hypoxia-induced radiotherapy resistance in non-small cell lung cancer by targeting the NF-κB/p65 pathway.
The MAEL expression in mitochondria of human spermatozoa and the association with asthenozoospermia.
Liquiritigenin regulates insulin sensitivity and ameliorates inflammatory responses in the nonalcoholic fatty liver by activation PI3K/AKT pathway.
Retinal Microenvironment-Protected Rhein-GFFYE Nanofibers Attenuate Retinal Ischemia-Reperfusion Injury via Inhibiting Oxidative Stress and Regulating Microglial/Macrophage M1/M2 Polarization.
Chlorogenic Acid Ameliorates Post-Infectious Irritable Bowel Syndrome by Regulating Extracellular Vesicles of Gut Microbes.
Novel role for epalrestat: protecting against NLRP3 inflammasome-driven NASH by targeting aldose reductase.
Chronic stress hinders sensory axon regeneration via impairing mitochondrial cristae and OXPHOS.
PI3K/mTOR inhibitors promote G6PD autophagic degradation and exacerbate oxidative stress damage to radiosensitize small cell lung cancer.
Platycodin D induces apoptotic cell death through PI3K/AKT and MAPK/ERK pathways and synergizes with venetoclax in acute myeloid leukemia.
Silence of linc00023 inhibits pyroptosis and promotes cell proliferation via regulating p53.
Zigui-Yichong-Fang protects against cyclophosphamide-induced premature ovarian insufficiency via the SIRT1/Foxo3a pathway.
ZeXieYin Formula alleviates TMAO-induced cognitive impairment by restoring synaptic plasticity damage.
Design, synthesis, and biological evaluation of a series of new anthraquinone derivatives as anti-ZIKV agents.
Long non-coding RNA colon cancer-associated transcript 1-Vimentin axis promoting the migration and invasion of HeLa cells.
Hemizygous variants in protein phosphatase 1 regulatory subunit 3F (PPP1R3F) are associated with a neurodevelopmental disorder characterized by developmental delay, intellectual disability and autistic features.
LINC00922 decoys SIRT3 to facilitate the metastasis of colorectal cancer through up-regulation the H3K27 crotonylation of ETS1 promoter.
PACS-2 deficiency aggravates tubular injury in diabetic kidney disease by inhibiting ER-phagy.
Distinct functions of EHMT1 and EHMT2 in cancer chemotherapy and immunotherapy.
EGR1 functions as a new host restriction factor for SARS-CoV-2 to inhibit virus replication through the E3 ubiquitin ligase MARCH8.
Collagen 1-mediated CXCL1 secretion in tumor cells activates fibroblasts to promote radioresistance of esophageal cancer.
Aspartyl-tRNA synthetase 2 orchestrates iron-sulfur metabolism in hematopoietic stem cells via fine-tuning alternative RNA splicing.
Mechanotransduction in response to ECM stiffening impairs cGAS immune signaling in tumor cells.
CPSF6 regulates alternative polyadenylation and proliferation of cancer cells through phase separation.
PP2C phosphatases Ptc1 and Ptc2 dephosphorylate PGK1 to regulate autophagy and aflatoxin synthesis in the pathogenic fungus Aspergillus flavus.
Self-promoted electroactive biomimetic mineralized scaffolds for bacteria-infected bone regeneration.
Cryo-EM structure of human O-GlcNAcylation enzyme pair OGT-OGA complex.
RNA 5-Methylcytosine regulators are associated with cell adhesion and predict prognosis of endometrial cancer.
Moschus ameliorates glutamate-induced cellular damage by regulating autophagy and apoptosis pathway.
Hepatic conversion of acetyl-CoA to acetate plays crucial roles in energy stress.
Hyodeoxycholic acid alleviates non-alcoholic fatty liver disease through modulating the gut-liver axis.
Icaritin ameliorates RANKL-mediated osteoclastogenesis and ovariectomy-induced osteoporosis.
Xue-Jie-San prevents the early development of colitis-associated intestinal fibrosis by blocking Notch1 and FGL1 signaling pathways.
FTZ promotes islet β-cell regeneration in T1DM mice via the regulation of nuclear proliferation factors.
Therapeutic Effect of Prolyl Endopeptidase Inhibitor in High-fat Diet-induced Metabolic Dysfunction-associated Fatty Liver Disease.
The arginine methyltransferase Prmt1 coordinates the germline arginine methylome essential for spermatogonial homeostasis and male fertility.
Unraveling the role of ZNF506 as a human PBS-pro-targeting protein for ERVP repression.
The potential of swine pseudorabies virus attenuated vaccine for oncolytic therapy against malignant tumors.
LncRNA PART1 Regulates Ovarian Carcinoma Development via the miR-150-5p/MYB Axis.
N6-methyladenosine-modified oncofetal lncRNA MIR4435-2HG contributed to stemness features of hepatocellular carcinoma cells by regulating rRNA 2'-O methylation.
METTL3-regulated m6A modification impairs the decidualization of endometrial stromal cells by regulating YTHDF2-mediated degradation of FOXO1 mRNA in endometriosis-related infertility.
N6-methyladenosine demethylase FTO related to hyperandrogenism in PCOS via AKT pathway.
Neurovascular protection of alisol A on cerebral ischemia mice through activating the AKT/GSK3β pathway.
Arsenic Exposure-Induced Acute Kidney Injury by Regulating SIRT1/PINK1/Mitophagy Axis in Mice and in HK-2 Cells.
FAM111B Acts as an Oncogene in Bladder Cancer.
ZDHHC9: a promising therapeutic target for triple-negative breast cancer through immune modulation and immune checkpoint blockade resistance.
Signaling protein abundance modulates the strength of the spindle assembly checkpoint.
Acteoside protects podocyte against apoptosis through regulating AKT/GSK-3β signaling pathway in db/db mice.
Soluble TREM2 ameliorates tau phosphorylation and cognitive deficits through activating transgelin-2 in Alzheimer's disease.
The ubiquitin E3 ligase MDM2 induces chemoresistance in colorectal cancer by degradation of ING3.
GDF15 deficiency hinders human trophoblast invasion to mediate pregnancy loss through downregulating Smad1/5 phosphorylation.
Neuroepithelial cell-transforming 1 promotes cardiac fibrosis via the Wnt/β-catenin signaling pathway.
Spinal TAOK2 contributes to neuropathic pain via cGAS-STING activation in rats.
Immunoglobulin G inhibits glucocorticoid-induced osteoporosis through occupation of FcγRI.
LncRNA AGPG Confers Endocrine Resistance in Breast Cancer by Promoting E2F1 Activity.
Intranasal inoculation of female BALB/c mice with replication-deficient human adenovirus type 5 expressing SARS-CoV-2 nucleocapsid protein aggravates lung pathology upon re-encountering the antigen.
Subconjunctival injection of human umbilical cord mesenchymal stem cells alleviates experimental allergic conjunctivitis via regulating T cell response.
ER-associated degradation in cystinosis pathogenesis and the prospects of precision medicine.
Polydatin improves vascular endothelial function by maintaining mitochondrial homeostasis under high glucose conditions.
Identification of KLHDC2 as an efficient proximity-induced degrader of K-RAS, STK33, β-catenin, and FoxP3.
Substrate-dependent interaction of SPOP and RACK1 aggravates cardiac fibrosis following myocardial infarction.
Vitisin A, as a Type of Pyranoanthocyanin, Suppresses Inflammation by Restricting Hematopoietic Stem Cell Differentiation toward Monocytes in Bone Marrow.
Screening and verifying the mutations in the LDLR and APOB genes in a Chinese family with familial hypercholesterolemia.
C3aR Antagonist Alleviates C3a Induced Tubular Profibrotic Phenotype Transition via Restoring PPARα/CPT-1α Mediated Mitochondrial Fatty Acid Oxidation in Renin-Dependent Hypertension.
Exosomal Linc00969 induces trastuzumab resistance in breast cancer by increasing HER-2 protein expression and mRNA stability by binding to HUR.
Proximal Tubular Lats2 Ablation Exacerbates Ischemia/Reperfusion Injury (IRI)-Induced Renal Maladaptive Repair through the Upregulation of P53.
KHDRBS3 accelerates glycolysis and promotes malignancy of hepatocellular carcinoma via upregulating 14-3-3ζ.
The HNF4A-CHPF pathway promotes proliferation and invasion through interactions with MAD1L1 in glioma.
MafB regulates NLRP3 inflammasome activation by sustaining p62 expression in macrophages.
PI3K/mTOR inhibitor VS-5584 combined with PLK1 inhibitor exhibits synergistic anti-cancer effects on non-small cell lung cancer.
URB597 exerts neuroprotective effects against transient brain ischemia injury in mice by regulating autophagic flux and necroptosis.
The novel peptide athycaltide-1 attenuates Ang II-induced pathological myocardial hypertrophy by reducing ROS and inhibiting the activation of CaMKII and ERK1/2.
FAM134B-induced endoplasmic reticulum (ER)-phagy exacerbates cisplatin-insulted hair cell apoptosis ：Possible relation to excessive ER stress.
DnaJA2 interacts with Japanese encephalitis virus NS3 via its C-terminal to promote viral infection.
Mutation of the ETS1 3'UTR interacts with miR-216a-3p to regulate granulosa cell apoptosis in sheep.
TSG-6 alleviates cerebral ischemia/reperfusion injury and blood-brain barrier disruption by suppressing ER stress-mediated inflammation.
The cryo-EM structure of the human ERAD retrotranslocation complex.
Dysregulated expression of slingshot protein phosphatase 1 (SSH1) disrupts circadian rhythm and WNT signaling associated to hepatocellular carcinoma pathogenesis.
Mechanism of BLIMP1/TRIM66/COX2 in human decidua participates in parturition†.
Network pharmacology-based strategy for predicting therapy targets of Ecliptae Herba on breast cancer.
Jin-Gui-Shen-Qi Wan ameliorates diabetic retinopathy by inhibiting apoptosis of retinal ganglion cells through the Akt/HIF-1α pathway.
Micheliolide prevents estrogen deficiency-induced bone loss via inhibiting osteoclast bone resorption.
Two polysaccharides from Rehmannia glutinosa: isolation, structural characterization, and hypoglycemic activities.
Disabled-2: a protein up-regulated by high molecular weight hyaluronan has both tumor promoting and tumor suppressor roles in ovarian cancer.
The ATF2/miR-3913-5p/CREB5 axis is involved in the cell proliferation and metastasis of colorectal cancer.
Astragalus polysaccharide restores insulin secretion impaired by lipopolysaccharides through the protein kinase B /mammalian target of rapamycin/glucose transporter 2 pathway.
CSTF2 mediated mRNA N(6)-methyladenosine modification drives pancreatic ductal adenocarcinoma m(6)A subtypes.
Molecular mechanism by which RRM2-inhibitor (cholagogue osalmid) plus bafilomycin A1 cause autophagic cell death in multiple myeloma.
MICALL2 participates in the regulation of epithelial-mesenchymal transition in alveolar epithelial cells - Potential roles in pulmonary fibrosis.
Sorafenib induces ferroptosis by promoting TRIM54-mediated FSP1 ubiquitination and degradation in hepatocellular carcinoma.
miR-552 promotes the proliferation and metastasis of intrahepatic cholangiocarcinoma by targeting FOXO1.
DEPDC1B-mediated USP5 deubiquitination of β-catenin promotes breast cancer metastasis by activating the wnt/β-catenin pathway.
Complement C1q drives microglia-dependent synaptic loss and cognitive impairments in a mouse model of lipopolysaccharide-induced neuroinflammation.
Comparative multi-omic analyses of cardiac mitochondrial stress in three mouse models of frataxin deficiency.
CNTN1 Aggravates Neuroinflammation and Triggers Cognitive Deficits in Male Mice by Boosting Crosstalk between Microglia and Astrocytes.
Pharmacokinetic and pharmacodynamic drug-drug interaction of Nomilin with atorvastatin in hyperlipidemic mice.
Dendrobium mixture ameliorates hepatic injury induced by insulin resistance in vitro and in vivo through the downregulation of AGE/RAGE/Akt signaling pathway.
Icariin promotes osteogenic differentiation through the mmu_circ_0000349/mmu-miR-138-5p/Jumonji domain-containing protein-3 axis.
Exploring the anticancer potential of Actinidia chinensis Planch root extracts (acRoots) on hepatocellular carcinoma: A molecular mechanism study.
Korean red ginseng formula attenuates non-alcoholic fatty liver disease in oleic acid-induced HepG2 cells and high-fat diet-induced rats.
LncBIRC3-OT promotes the malignant progression of glioma by interacting with RELA to upregulate stanniocalcin-1 expression.
Network pharmacology and in vitro experimental verification to reveal the mechanism of Astragaloside IV against kidney ischemia-reperfusion injury.
Multi-omics reveals aging-related pathway in natural aging mouse liver.
Rab11-FIP4 interacts with ARF5 to promote cancer stemness in hepatocellular carcinoma.
Agaricus blazei Murrill Polysaccharide Attenuates Periodontitis via H(2) S/NRF2 Axis-Boosted Appropriate Level of Autophagy in PDLCs.
ADAR1 exacerbates ischemic brain injury via astrocyte-mediated neuron apoptosis.
Antimicrobial agent chloroxylenol targets β‑catenin‑mediated Wnt signaling and exerts anticancer activity in colorectal cancer.
LKB1 loss promotes colorectal cancer cell metastasis through regulating TNIK expression and actin cytoskeleton remodeling.
Macrophage microvesicle-derived circ_YTHDF2 in methamphetamine-induced chronic lung injury.
BMP4 Regulates EMT to be Involved in non-Syndromic Cleft lip With or Without Palate.
Inhibition of the SREBP pathway prevents SARS-CoV-2 replication and inflammasome activation.
RACK1 promotes porcine reproductive and respiratory syndrome virus infection in Marc-145 cells through ERK1/2 activation.
Suppression of the gut microbiota-bile acid-FGF19 axis in patients with atrial fibrillation.
Characterization of circRNAs in established osimertinib‑resistant non‑small cell lung cancer cell lines.
ATG7-mediated autophagy protects human gingival myofibroblasts from irradiation-induced apoptosis.
Electroacupuncture Ameliorates Hypothalamic‒Pituitary‒Adrenal Axis Dysfunction Induced by Surgical Trauma in Mice Through the Hypothalamic Oxytocin System.
Inhibition of TMEM16A improves cisplatin-induced acute kidney injury via preventing DRP1-mediated mitochondrial fission.
Targeting histone deacetylase suppresses tumor growth through eliciting METTL14-modified m(6) A RNA methylation in ocular melanoma.
Blockade of de novo pyrimidine biosynthesis triggers autophagic degradation of oncoprotein FLT3-ITD in acute myeloid leukemia.
Orientin inhibits inflammation in chondrocytes and attenuates osteoarthritis through Nrf2/NF-κB and SIRT6/NF-κB pathway.
Protective effect of liriodendrin on IgG immune complex-induced acute lung injury via inhibiting SRC/STAT3/MAPK signaling pathway: a network pharmacology research.
Epinodosin suppresses the proliferation, invasion, and migration of esophageal squamous cell carcinoma by mediating miRNA-143-3p/Bcl-2 axis.
IGF2BP3 drives gallbladder cancer progression by m6A-modified CLDN4 and inducing macrophage immunosuppressive polarization.
Rac GTPase activating protein 1 promotes the glioma growth by regulating the expression of MCM3.
C-IGF1R encoded by cIGF1R acts as a molecular switch to restrict mitophagy of drug-tolerant persister tumour cells in non-small cell lung cancer.
SATB1 promotes osteogenic differentiation of diabetic rat BMSCs through MAPK signalling activation.
Curcumin nanoemulsions inhibit oral squamous cell carcinoma cell proliferation by PI3K/Akt/mTOR suppression and miR-199a upregulation: A preliminary study.
Pregnane X receptor (PXR) deficiency protects against spinal cord injury by activating NRF2/HO-1 pathway.
RBM25 regulates hypoxic cardiomyocyte apoptosis through CHOP-associated endoplasmic reticulum stress.
HIF‑1α and RACGAP1 promote the progression of hepatocellular carcinoma in a mutually regulatory way.
Enrofloxacin hydrochloride toxicological effects on crucian carp reflected by serological changes and neurotoxicity.
Mulberrin alleviates triclocarban induced hepatic apoptosis and inflammation by regulating the ROS/NF-κB pathway in grass carp.
Knockdown of Bach1 protects periodontal bone regeneration from inflammatory damage.
Autophagy and LC3-associated phagocytosis contribute negatively to the killing capability of THP-1-derived macrophages against Candida albicans at the mid-stage.
The ligation between ERMAP, galectin-9 and dectin-2 promotes Kupffer cell phagocytosis and antitumor immunity.
circAP1M2 activates ATG9A-associated autophagy by inhibiting miR-1249-3p to promote cisplatin resistance in oral squamous cell carcinoma.
PSMC2 knockdown exerts an anti-tumor role in nasopharyngeal carcinoma through regulating AKT signaling pathway.
Dauricine regulates prostate cancer progression by inhibiting PI3K/AKT-dependent M2 polarization of macrophages.
TIPE2 ameliorates neuroinflammation and cognitive impairment in sepsis-associated encephalopathy through regulating RhoA/ROCK2-NF-κB signaling pathway.
The role of miR-199a-3p in inhibiting the proliferation of spermatogonial stem cells under heat stress.
Ethanol extract of Herpetospermum caudigerum Wall ameliorates psoriasis-like skin inflammation and promotes degradation of keratinocyte-derived ICAM-1 and CXCL9.
Resurrection of 2'-5'-oligoadenylate synthetase 1 (OAS1) from the ancestor of modern horseshoe bats blocks SARS-CoV-2 replication.
Melatonin attenuates sevoflurane-induced hippocampal damage and cognitive deficits in neonatal mice by suppressing CypD in parvalbumin neurons.
Multi-parametric MRI assessment of melatonin regulating the polarization of microglia in rats after cerebral ischemia/reperfusion injury.
Inhibition of ferroptosis alleviates chronic unpredictable mild stress-induced depression in mice via tsRNA-3029b.
Fucoidan promotes angiogenesis and accelerates wound healing through AKT/Nrf2/HIF-1α signalling pathway.
Sphingosine kinase 1/S1P receptor signaling axis is essential for cellular uptake of Neisseria meningitidis in brain endothelial cells.
Autophagy regulation and protein kinase activity of PIK3C3 controls sertoli cell polarity through its negative regulation on SCIN (scinderin).
Gelation of cytoplasmic expanded CAG RNA repeats suppresses global protein synthesis.
Elaidic acid induced hepatocyte pyroptosis via autophagy-CTSB-NLRP3 pathway.
The protective effects of EGCG was associated with HO-1 active and microglia pyroptosis inhibition in experimental intracerebral hemorrhage.
Identifying the personalized driver gene sets maximally contributing to abnormality of transcriptome phenotype in glioblastoma multiforme individuals.
Cyclovirobuxine D alleviates aldosterone-induced myocardial hypertrophy by protecting mitochondrial function depending on the mutual regulation of Nrf2-SIRT3.
Colorectal cancer tissue-originated spheroids reveal tumor intrinsic signaling pathways and mimic patient clinical chemotherapeutic response as a rapid and valid model.
An oral triple pill-based cocktail effectively controls acute myeloid leukemia with high translation.
The novel lncRNA-9802/miR-1646 axis affects cell proliferation of DF-1 by regulating Bax/Bcl-2 signaling pathway.
The role of the Gas6/TAM signal pathway in the LPS-induced pulmonary epithelial cells injury.
A Novel EYA1 Mutation Causing Alternative RNA Splicing in a Chinese Family With Branchio-Oto Syndrome: Implications for Molecular Diagnosis and Clinical Application.
The expression and distribution of TACAN in human and rat bladders.
Design, synthesis, and biological evaluation of carbonyl-hydrazine-1-carboxamide derivatives as anti-hepatic fibrosis agents targeting Nur77.
SIRT1 is an actionable target to restore p53 function in HPV-associated cancer therapy.
The heterogeneity of tumour immune microenvironment revealing the CRABP2/CD69 signature discriminates distinct clinical outcomes in breast cancer.
GBP2 upregulated in LPS-stimulated macrophages-derived exosomes accelerates septic lung injury by activating epithelial cell NLRP3 signaling.
Butyrate alleviates renal fibrosis in CKD by regulating NLRP3-mediated pyroptosis via the STING/NF-κB/p65 pathway.
Linderalactone mitigates diabetic cardiomyopathy in mice via suppressing the MAPK/ATF6 pathway.
4-Octyl itaconate inhibits inflammation to attenuate psoriasis as an agonist of oxeiptosis.
Nuciferine protects against lipopolysaccharide-induced endometritis via inhibiting ferroptosis and modulating AMPKα/mTOR/HIF-1α signaling axis.
Attenuated Salmonella-delivered PD-1 siRNA enhances the antitumor effects of EZH2 inhibitors in colorectal cancer.
Ferritin was involved in interleukin-17A enhanced osteogenesis through autophagy activation.
The role of blood podoplanin in patients with viral myocarditis.
3, 4-Benzopyrene (Bap) aggravated abdominal aortic aneurysm formation by targeting pyroptosis in smooth muscle cells through ET-1 mediated NLRP3-inflammasome activation.
Icaritin inhibits endometrial carcinoma cells by suppressing O-GlcNAcylation of FOXC1.
Sanguisorba officinalis ethyl acetate extract attenuates ulcerative colitis through inhibiting PI3K-AKT/NF-κB/ STAT3 pathway uncovered by single-cell RNA sequencing.
A large-scale transcriptional analysis reveals herb-derived ginsenoside F2 suppressing hepatocellular carcinoma via inhibiting STAT3.
Comprehensive analysis of cuproptosis genes and cuproptosis-related genes as prognosis factors in esophageal squamous cell carcinoma.
Combination of PARP inhibitor and CDK4/6 inhibitor modulates cGAS/STING-dependent therapy-induced senescence and provides "one-two punch" opportunity with anti-PD-L1 therapy in colorectal cancer.
Oxytocin alleviates cognitive and memory impairments by decreasing hippocampal microglial activation and synaptic defects via OXTR/ERK/STAT3 pathway in a mouse model of sepsis-associated encephalopathy.
Elastic modulus of hydrogel regulates osteogenic differentiation via liquid-liquid phase separation of YAP.
Musashi-2 binds with Fbxo6 to induce Rnaset2 ubiquitination and chemokine signaling pathway during vascular smooth muscle cell phenotypic switch in atherosclerosis.
ADAMTS12 promotes oxaliplatin chemoresistance and angiogenesis in gastric cancer through VEGF upregulation.
CircTNPO1 promotes the tumorigenesis of osteosarcoma by sequestering miR-578 to upregulate WNT5A expression.
β-hydroxybutyrate impairs the directionality of migrating neutrophils through inhibiting the autophagy-dependent degradation of Cdc42 and Rac1 in ketotic cows.
Elucidation of the mechanisms and molecular targets of KeChuanLiuWei-Mixture for treatment of severe asthma based on network pharmacology.
The mixture of Radix isatidis, Forsythiae, and Gypsum alleviates lipopolysaccharide-induced fever in broilers by inhibition of TLR4/NF-κB signaling pathway.
DNA damage-mediated cellular senescence promotes hand-foot syndrome that can be relieved by thymidine prodrug.
Targeting USP8 Inhibits O-GlcNAcylation of SLC7A11 to Promote Ferroptosis of Hepatocellular Carcinoma via Stabilization of OGT.
A HER2-targeted Antibody-Drug Conjugate, RC48-ADC, Exerted Promising Antitumor Efficacy and Safety with Intravesical Instillation in Preclinical Models of Bladder Cancer.
KLF5 Promotes Tumor Progression and Parp Inhibitor Resistance in Ovarian Cancer.
Withdrawal.
Photochemistry and photobiology 2023 Nov-Dec;99(6):1501
Blue Light Inhibits Proliferation of Metastatic Cancer Cells by Regulating Translational Initiation: A Synergistic Property with Anticancer Drugs.
Flavinated SDHA underlies the change in intrinsic optical properties of oral cancers.
Cryo-electron tomography of NLRP3-activated ASC complexes reveals organelle co-localization.
Microglial voltage-dependent anion channel 1 signaling modulates sleep deprivation-induced transition to chronic postsurgical pain.
A conserved mechanism for JNK-mediated loss of Notch function in advanced prostate cancer.
Uncoupling Protein 3 Promotes the Myogenic Differentiation of Type IIb Myotubes in C2C12 Cells.
Covalent 14-3-3 Molecular Glues and Heterobifunctional Molecules Against Nuclear Transcription Factors and Regulators.
Novel acridine-based LSD1 inhibitors enhance immune response in gastric cancer.
PGAM5 degrades PDCoV N protein and activates type I interferon to antagonize viral replication.
Adhesion G Protein-Coupled Receptor G2 Promotes Hepatocellular Carcinoma Progression and Serves as a Neutrophil-Related Prognostic Biomarker.
PBRM1 mutation and WDR72 expression as potential combinatorial biomarker for predicting the response to Nivolumab in patients with ccRCC: a tumor marker prognostic study.
PFKP confers chemoresistance by upregulating ABCC2 transporter in non-small cell lung cancer.
The yeast prion protein Sup35 initiates α-synuclein pathology in mouse models of Parkinson's disease.
Selective activator of human ClpP triggers cell cycle arrest to inhibit lung squamous cell carcinoma.
Extracellular vesicle-derived silk fibroin nanoparticles loaded with MFGE8 accelerate skin ulcer healing by targeting the vascular endothelial cells.
INPP5D regulates inflammasome activation in human microglia.
Photothermal-Ionic-Pharmacotherapy of Myocardial Infarction with Enhanced Angiogenesis and Antiapoptosis.
METTL9-SLC7A11 axis promotes hepatocellular carcinoma progression through ferroptosis inhibition.
SETD4 inhibits prostate cancer development by promoting H3K27me3-mediated NUPR1 transcriptional repression and cell cycle arrest.
The deubiquitinating enzyme USP19 facilitates hepatocellular carcinoma progression through stabilizing YAP.
A bacteria-derived tetramerized protein ameliorates nonalcoholic steatohepatitis in mice via binding and relocating acetyl-coA carboxylase.
p53-responsive CMBL reprograms glucose metabolism and suppresses cancer development by destabilizing phosphofructokinase PFKP.
Inhibiting G6PD by quercetin promotes degradation of EGFR T790M mutation.
Single-cell transcriptomics identifies a WNT7A-FZD5 signaling axis that maintains fallopian tube stem cells in patient-derived organoids.
PD-L1-mediated immune evasion in triple-negative breast cancer is linked to the loss of ZNF652.
The yeast protein Ure2p triggers Tau pathology in a mouse model of tauopathy.
Neuro-Inspired Biomimetic Microreactor for Sensory Recovery and Hair Follicle Neogenesis under Skin Burns.
The Role of ZNF275/AKT Pathway in Carcinogenesis and Cisplatin Chemosensitivity of Cervical Cancer Using Patient-Derived Xenograft Models.
Fucoidan Ameliorates Ferroptosis in Ischemia-reperfusion-induced Liver Injury through Nrf2/HO-1/GPX4 Activation.
LSM14B is essential for oocyte meiotic maturation by regulating maternal mRNA storage and clearance.
Hsa_circ_0009092/miR-665/NLK signaling axis suppresses colorectal cancer progression via recruiting TAMs in the tumor microenvironment.
LINC02086 promotes cell viability and inhibits cell apoptosis in breast cancer by sponging miR-6757-5p and up-regulating EPHA2.
OTUD1 ameliorates cerebral ischemic injury through inhibiting inflammation by disrupting K63-linked deubiquitination of RIP2.
Lnc-PTCHD4-AS inhibits gastric cancer through MSH2-MSH6 dimerization and ATM-p53-p21 activation.
Mitoguardin 1 and 2 promote granulosa cell proliferation by activating AKT and regulating the Hippo-YAP1 signaling pathway.
Knockdown of TACC3 inhibits tumor cell proliferation and increases chemosensitivity in pancreatic cancer.
Long noncoding RNA NONHSAT160169.1 promotes resistance via hsa-let-7c-3p/SOX2 axis in gastric cancer.
RMI1 facilitates repair of ionizing radiation-induced DNA damage and maintenance of genomic stability.
IFN-γ in ovarian tumor microenvironment upregulates HLA-E expression and predicts a poor prognosis.
The Interaction between SARS-CoV-2 Nucleocapsid Protein and UBC9 Inhibits MAVS Ubiquitination by Enhancing Its SUMOylation.
SOX18 Promotes the Proliferation of Dermal Papilla Cells via the Wnt/β-Catenin Signaling Pathway.
Remdesivir Derivative VV116 Is a Potential Broad-Spectrum Inhibitor of Both Human and Animal Coronaviruses.
BioE3 identifies specific substrates of ubiquitin E3 ligases.
Mid-old cells are a potential target for anti-aging interventions in the elderly.
ALS/FTD-associated mutation in cyclin F inhibits ER-Golgi trafficking, inducing ER stress, ERAD and Golgi fragmentation.
Heteromeric formation with βA3 protects the low thermal stability of βB1-L116P.
Ascomylactam C Induces an Immunogenic Cell Death Signature via Mitochondria-Associated ER Stress in Lung Cancer and Melanoma.
Hepatocyte integrity depends on c-Jun-controlled proliferation in Schistosoma mansoni infected mice.
MiniBAR/GARRE1 is a dual Rac and Rab effector required for ciliogenesis.
LMP2 and TAP2 impair tumor growth and metastasis by inhibiting Wnt/β-catenin signaling pathway and EMT in cervical cancer.
Inhibiting Rev-erbα-mediated ferroptosis alleviates susceptibility to myocardial ischemia-reperfusion injury in type 2 diabetes.
BCAS2 Participates in Insulin Synthesis and Secretion via mRNA Alternative Splicing in Mice.
Vitamin D Attenuates Ulcerative Colitis by Inhibiting ACSL4-Mediated Ferroptosis.
PHB2 Alleviates Neurotoxicity of Prion Peptide PrP(106-126) via PINK1/Parkin-Dependent Mitophagy.
Covalent Degrader of the Oncogenic Transcription Factor β-Catenin.
Exploiting the Cullin E3 Ligase Adaptor Protein SKP1 for Targeted Protein Degradation.
Cinnamaldehyde Alleviates Bone Loss by Targeting Oxidative Stress and Mitochondrial Damage via the Nrf2/HO-1 Pathway in BMSCs and Ovariectomized Mice.
Resensitizing Paclitaxel-Resistant Ovarian Cancer via Targeting Lipid Metabolism Key Enzymes CPT1A, SCD and FASN.
Agathis dammara Extract and its Monomer Araucarone Attenuate Abdominal Aortic Aneurysm in Mice.
MiR-337-3p improves metabolic-associated fatty liver disease through regulation of glycolipid metabolism.
JUN mediates glucocorticoid resistance by stabilizing HIF1a in T cell acute lymphoblastic leukemia.
Fibromodulin overexpression drives oral squamous cell carcinoma via activating downstream EGFR signaling.
FUS-dependent microRNA deregulations identify TRIB2 as a druggable target for ALS motor neurons.
The splicing factor DHX38 enables retinal development through safeguarding genome integrity.
CD9 exacerbates pathological cardiac hypertrophy through regulating GP130/STAT3 signaling pathway.
Photoperiod Induces the Epigenetic Change of the GNAQ Gene in OVX+E(2) Ewes.
Blockage of CacyBP inhibits macrophage recruitment and improves anti-PD-1 therapy in hepatocellular carcinoma.
HDAC3 and HDAC8 PROTAC dual degrader reveals roles of histone acetylation in gene regulation.
The proteomics analysis of extracellular vesicles revealed the possible function of heat shock protein 60 in Helicobacter pylori infection.
Tripartite motif 31 drives gastric cancer cell proliferation and invasion through activating the Wnt/β-catenin pathway by regulating Axin1 protein stability.
Structural determinants specific for retromer protein sorting nexin 5 in regulating subcellular retrograde membrane trafficking.
Deciphering the anti-renal fibrosis mechanism of triptolide in diabetic nephropathy by the integrative approach of network pharmacology and experimental verification.
Extracts of Oldenlandia diffusa protects chondrocytes via inhibiting apoptosis and associated inflammatory response in osteoarthritis.
The total alkaloids of Sophora alopecuroides L. improve depression-like behavior in mice via BDNF-mediated AKT/mTOR signaling pathway.
Loss of TMEM106B exacerbates Tau pathology and neurodegeneration in PS19 mice.
Quantitatively Lighting up the Spatial Organization of CD47/SIRPα Immune Checkpoints on the Cellular Membrane with Single-Molecule Localization Microscopy.
Integrating Metabolomics and Network Pharmacology to Explore the Mechanism of Xiao-Yao-San in the Treatment of Inflammatory Response in CUMS Mice.
Progenitor-like exhausted SPRY1(+)CD8(+) T cells potentiate responsiveness to neoadjuvant PD-1 blockade in esophageal squamous cell carcinoma.
Spatial proteo-transcriptomic profiling reveals the molecular landscape of borderline ovarian tumors and their invasive progression.
IDH1(R132H) mutation increases radiotherapy efficacy and a 4-gene radiotherapy-related signature of WHO grade 4 gliomas.
Mechanism underlying the effect of Pulsatilla decoction in hepatocellular carcinoma treatment: a network pharmacology and in vitro analysis.
Accelerating Wound Closure With Metrnl in Normal and Diabetic Mouse Skin.
Cholesterol mediated ferroptosis suppression reveals essential roles of Coenzyme Q and squalene.
Col3a1 delivered via extracellular vesicles of Sertoli cells is essential for mice Sertoli cell proliferation.
Salt-inducible kinases regulate androgen synthesis in theca cells by enhancing CREB signaling.
Resistance exercise alleviates dexamethasone-induced muscle atrophy via Sestrin2/MSTN pathway in C57BL/6J mice.
MnO(2) nanoparticles and MnSO(4) differentially affected hepatic lipid metabolism through miR-92a/acsl3-dependent de novo lipogenesis in yellow catfish Pelteobagrusfulvidraco.
Integrated proteomics and phosphoproteomics analyses of esophageal cancer cells with different invasive abilities.
Skeletal muscle-derived FSTL1 starting up angiogenesis by regulating endothelial junction via activating Src pathway can be upregulated by hydrogen sulfide.
MARCH8 downregulation modulates profibrotic responses including myofibroblast differentiation.
Intrathecal delivery of AAV-NDNF ameliorates disease progression of ALS mice.
Restricted tRNA methylation by intermolecular disulfide bonds in DNMT2/TRDMT1.
Nrf2 depletion in the context of loss-of-function Keap1 leads to mitolysosome accumulation.
STING promotes ferroptosis through NCOA4-dependent ferritinophagy in acute kidney injury.
Exosomes derived from schwann cells alleviate mitochondrial dysfunction and necroptosis after spinal cord injury via AMPK signaling pathway-mediated mitophagy.
High-fat diet induces C-reactive protein secretion, promoting lung adenocarcinoma via immune microenvironment modulation.
Follicle-stimulating hormone orchestrates glucose-stimulated insulin secretion of pancreatic islets.
Butyrate prevents the migration and invasion, and aerobic glycolysis in gastric cancer via inhibiting Wnt/β-catenin/c-Myc signaling.
Synergistic ferroptosis-starvation therapy for bladder cancer based on hyaluronic acid modified metal-organic frameworks.
Reactive oxygen species-responsive mitochondria-targeted liposomal quercetin attenuates retinal ischemia-reperfusion injury via regulating SIRT1/FOXO3A and p38 MAPK signaling pathways.
Klotho improves cardiac fibrosis, inflammatory cytokines, ferroptosis, and oxidative stress in mice with myocardial infarction.
Proline-rich 11 (PRR11) promotes the progression of cutaneous squamous cell carcinoma by activating the EGFR signaling pathway.
Mast cells disrupt the duodenal mucosal integrity: Implications for the mechanisms of barrier dysfunction in functional dyspepsia.
Scalable preparation of osteogenic micro-tissues derived from hESC-derived immunity-and-matrix-regulatory cells within porous microcarriers in suspension culture.
Andrographolide exerts anti-respiratory syncytial virus activity by up-regulating heme oxygenase-1 independent of interferon responses in human airway epithelial cells.
TRIP13 overexpression promotes gefitinib resistance in non‑small cell lung cancer via regulating autophagy and phosphorylation of the EGFR signaling pathway.
Targeting PI3Kα overcomes resistance to KRas(G12C) inhibitors mediated by activation of EGFR and/or IGF1R.
ZD6474 attenuates TGF-β1-induced fibrosis in human Tenon fibroblasts and inhibits neovascularization via AKT-mTOR signaling pathway.
LZTFL1 inhibits kidney tumor cell growth by destabilizing AKT through ZNRF1-mediated ubiquitin proteosome pathway.
Gli1 depletion induces oxidative stress and apoptosis of nucleus pulposus cells via Fos in intervertebral disc degeneration.
The pan-cancer analysis of the oncogenic role of FAM72A as a BRCA prognostic biomarker and immunotherapeutic target.
Circular RNA SLTM as a miR-421-competing endogenous RNA to mediate HMGB2 expression stimulates apoptosis and inflammation in arthritic chondrocytes.
Analysis of CRSsNP Proteome Using a Highly Multiplexed Approach in Nasal Mucus.
Silencing of adipocyte enhancer-binding protein 1 (AEBP1) alleviates renal fibrosis in vivo and in vitro via inhibition of the β-catenin signaling pathway.
CircRNA_0017076 acts as a sponge for miR-185-5p in the control of epithelial-to-mesenchymal transition of tubular epithelial cells during renal interstitial fibrosis.
Rational design of a polysaccharide-based viral mimicry nanocomplex for potent gene silencing in inflammatory tissues.
The deubiquitinating enzyme UCHL3 promotes anaplastic thyroid cancer progression and metastasis through Hippo signaling pathway.
TRIM28 negatively regulates the RLR signaling pathway by targeting MAVS for degradation via K48-linked polyubiquitination.
The Wnt pathway protein Dvl1 targets somatostatin receptor 2 for lysosome-dependent degradation.
Apicidin attenuates memory deficits by reducing the Aβ load in APP/PS1 mice.
Transcriptomic and antiviral analyses of PoIFN-Delta5 against porcine enteric viruses in porcine intestinal epithelial cells.
Deleting UL49.5 in duck plague virus causes attachment, entry and spread defects.
Ambient particulate matter exposure plus chronic ethanol ingestion exacerbates hepatic fibrosis by triggering the mitochondrial ROS-ferroptosis signaling pathway in mice.
Microcystin leucine arginine induces human sperm damage: Involvement of the Ca(2+)/CaMKKβ/AMPK pathway.
Genome-wide CRISPR screens identify ILF3 as a mediator of mTORC1-dependent amino acid sensing.
Deciphering the Clinical Significance and Kinase Functions of GSK3α in Colon Cancer by Proteomics and Phosphoproteomics.
Phenotypic Heterogeneity Analysis of APC-Mutant Colon Cancer by Proteomics and Phosphoproteomics Identifies RAI14 as a Key Prognostic Determinant in East Asians and Westerners.
Characterization of GSDME in amphioxus provides insights into the functional evolution of GSDM-mediated pyroptosis.
Protein Kinase CK2 Promotes Proliferation, Abnormal Differentiation, and Proinflammatory Cytokine Production of Keratinocytes via Regulation of STAT3 and Akt Pathways in Psoriasis.
A human dynein heavy chain mutation impacts cortical progenitor cells causing developmental defects, reduced brain size and altered brain architecture.
Ischemic accumulation of succinate induces Cdc42 succinylation and inhibits neural stem cell proliferation after cerebral ischemia/reperfusion.
Pgp3 protein of Chlamydia trachomatis inhibits apoptosis via HO-1 upregulation mediated by PI3K/Akt activation.
Klotho protects against aged myocardial cells by attenuating ferroptosis.
N6-Methyladenosine-Mediated Up-Regulation of FZD10 Regulates Liver Cancer Stem Cells' Properties and Lenvatinib Resistance Through WNT/β-Catenin and Hippo Signaling Pathways.
In vivo anti-hyperuricemia and anti-gouty arthritis effects of the ethanol extract from Amomumvillosum Lour.
A low-salt diet with candesartan administration is associated with acute kidney injury in nephritis by increasing nitric oxide.
Magnolol improves Alzheimer's disease-like pathologies and cognitive decline by promoting autophagy through activation of the AMPK/mTOR/ULK1 pathway.
Autophagy inhibition and ferroptosis activation during atherosclerosis: Hypoxia-inducible factor 1α inhibitor PX-478 alleviates atherosclerosis by inducing autophagy and suppressing ferroptosis in macrophages.
Virulence assessment of four Glaesserella parasuis strains isolated in Liaoning province of China.
Chemoproteomics reveals arctigenin as a phagophore-closure blocker via targeting ESCRT-I subunit VPS28.
An ultrasensitive GSH-specific fluorescent probe unveils celastrol-induced ccRCC ferroptosis.
NSUN2-mediated m(5) C RNA methylation dictates retinoblastoma progression through promoting PFAS mRNA stability and expression.
TREM2 Insufficiency Protects against Pulmonary Fibrosis by Inhibiting M2 Macrophage Polarization.
Baicalein ameliorates Alzheimer's disease via orchestration of CX3CR1/NF-κB pathway in a triple transgenic mouse model.
Syringaresinol attenuates osteoarthritis via regulating the NF-κB pathway.
Stabilization of estrogen receptor α by USP37 contributes to the progression of breast cancer.
Effect of High-Intensity Interval Training on Fatty Infiltration After Delayed Rotator Cuff Repair in a Mouse Model.
A Novel Role for RILP in Regulating Osteoclastogenesis and Bone Resorption.
BX795, a kinase inhibitor, inhibit duck plague virus infection via targeting US3 kinase.
Orai1 is an Entotic Ca(2+) Channel for Non-Apoptotic Cell Death, Entosis in Cancer Development.
Malic Enzyme 1 as a Novel Anti-Ferroptotic Regulator in Hepatic Ischemia/Reperfusion Injury.
[Effects of Peroxisome Proliferator-Activated Receptor γ on Modulating Angiopoietin-Like Protein 4 Synthesis in Caco-2 Cells Exposed to Clostridium butyricum].
Bisphenol A induces testicular oxidative stress in mice leading to ferroptosis.
Characterization of the protein expression and localization of hnRNP family members during murine spermatogenesis.
Resistance to anti-HER2 therapy associated with the TSC2 nonsynonymous variant c.4349 C > G (p.Pro1450Arg) is reversed by CDK4/6 inhibitor in HER2-positive breast cancer.
Involvement of canonical Wnt/β-catenin signaling in the extinction of auditory fear conditioning in male mice.
miR-183-5p overexpression orchestrates collective invasion in salivary adenoid cystic carcinoma through the FAT1/YAP1 signaling pathway.
KLF9 Promotes Osteogenic Differentiation of Dental Stem Cells by Negatively Regulating Notch1 Mediated Signaling Pathway.
MicroRNA-143 acts as a tumor suppressor through Musashi-2/DLL1/Notch1 and Musashi-2/Snail1/MMPs axes in acute myeloid leukemia.
Losartan attenuates acetic acid enema-induced visceral hypersensitivity by inhibiting the ACE1/Ang II/AT1 receptor axis in enteric glial cells.
TMEM106B regulates microglial proliferation and survival in response to demyelination.
Differential regulation of ATP hydrolysis of RIG-I-like receptors by transactivation response RNA-binding protein.
Discovery of acridine-based LSD1 inhibitors as immune activators targeting LSD1 in gastric cancer.
The mechanism of STING autoinhibition and activation.
TMT-based quantitative proteomic analysis of spheroid cells of endometrial cancer possessing cancer stem cell properties.
Intracellular Vimentin Regulates the Formation of Classical Swine Fever Virus Replication Complex through Interaction with NS5A Protein.
Interplay between Furin and Sialoglycans in Modulating Adeno-Associated Viral Cell Entry.
MALAT1 participates in the role of platelet-rich plasma exosomes in promoting wound healing of diabetic foot ulcer.
SCARECROW maintains the stem cell niche in Arabidopsis roots by ensuring telomere integrity.
Akt2 deficiency alleviates oxidative stress in the heart and liver via up-regulating SIRT6 during high-fat diet-induced obesity.
MYO10 regulates genome stability and cancer inflammation through mediating mitosis.
16p11.2 haploinsufficiency reduces mitochondrial biogenesis in brain endothelial cells and alters brain metabolism in adult mice.
CX3CR1(hi) macrophages sustain metabolic adaptation by relieving adipose-derived stem cell senescence in visceral adipose tissue.
β-Hydroxy-β-methyl Butyrate Regulates the Lipid Metabolism, Mitochondrial Function, and Fat Browning of Adipocytes.
The mechanisms to dispose of misfolded proteins in the endoplasmic reticulum of adipocytes.
ARL6IP1 mediates small-molecule-induced alleviation of Alzheimer pathology through FXR1-dependent BACE1 translation initiation.
Hypermetabolism in mice carrying a near-complete human chromosome 21.
Epsin1-mediated exosomal sorting of Dll4 modulates the tubular-macrophage crosstalk in diabetic nephropathy.
Unraveling the potential of senescence-related genes in guiding clinical therapy of lung adenocarcinoma patients.
VSTM2L contributes to anoikis resistance and acts as a novel biomarker for metastasis and clinical outcome in ovarian cancer.
Dengue Virus 2 NS2B Targets MAVS and IKKε to Evade the Antiviral Innate Immune Response.
Pulsatilla Decoction and its bioactive component β-peltatin induce G2/M cell cycle arrest and apoptosis in pancreatic cancer.
LncRNA CASC19 promotes gastric cancer progression through preventing CREB1 protein ubiquitin/proteasome-dependent degradation.
The Nrf2/HMGB1/NF-κB axis modulates chondrocyte apoptosis and extracellular matrix degradation in osteoarthritis.
RSL1D1 knockdown induces ferroptosis and mediates ferrous iron accumulation in senescent cells by inhibiting FTH1 mRNA stability.
Genetic and protein interaction studies between the ciliary dyslexia candidate genes DYX1C1 and DCDC2.
NEK2 promotes esophageal squamous cell carcinoma cell proliferation, migration and invasion through the Wnt/β-catenin signaling pathway.
Metformin promotes female germline stem cell proliferation by upregulating Gata-binding protein 2 with histone β-hydroxybutyrylation.
Discovery of Potent and Wild-Type-Sparing Fourth-Generation EGFR Inhibitors for Treatment of Osimertinib-Resistance NSCLC.
Tricyclic antidepressants induce liver inflammation by targeting NLRP3 inflammasome activation.
Dietary Isoquercetin Reduces Hepatic Cholesterol and Triglyceride in NAFLD Mice by Modulating Bile Acid Metabolism via Intestinal FXR-FGF15 Signaling.
Poly (ADP-ribose) polymerases 16 triggers pathological cardiac hypertrophy via activating IRE1α-sXBP1-GATA4 pathway.
Discovering a Reversible Male Contraceptive Agent Derived from Lonidamine.
UQCRFS1 serves as a prognostic biomarker and promotes the progression of ovarian cancer.
Brain-Derived Estrogen Regulates Neurogenesis, Learning and Memory with Aging in Female Rats.
Base editing-mediated one-step inactivation of the Dnmt gene family reveals critical roles of DNA methylation during mouse gastrulation.
FAM210A Regulates Mitochondrial Translation and Maintains Cardiac Mitochondrial Homeostasis.
Azelaic Acid Regulates the Renin-Angiotensin System and Improves Colitis Based on Network Pharmacology and Experimentation.
Dietary intake of α-ketoglutarate ameliorates α-synuclein pathology in mouse models of Parkinson's disease.
FBXW7β loss-of-function enhances FASN-mediated lipogenesis and promotes colorectal cancer growth.
Epigenetically silenced lncRNA SNAI3-AS1 promotes ferroptosis in glioma via perturbing the m(6)A-dependent recognition of Nrf2 mRNA mediated by SND1.
Establishment of highly metastatic ovarian cancer model with omental tropism via in vivo selection.
Piezo1 induces endothelial responses to shear stress via soluble adenylyl Cyclase-IP(3)R2 circuit.
C9ORF72 suppresses JAK-STAT mediated inflammation.
Isoflavones Mediate Dendritogenesis Mainly through Estrogen Receptor α.
ERK and USP5 govern PD-1 homeostasis via deubiquitination to modulate tumor immunotherapy.
Insight into Pathogenic Mechanism Underlying the Hereditary Cataract Caused by βB2-G149V Mutation.
Characterization of an allosteric inhibitor of fungal-specific C-24 sterol methyltransferase to treat Candida albicans infections.
LncRNA-PVT1 was identified as a key regulator for TMZ resistance and STAT-related pathway in glioma.
Development and validation of a selenium metabolism regulators associated prognostic model for hepatocellular carcinoma.
Profiling the impact of the promoters on CRISPR-Cas12a system in human cells.
Comprehensive analysis of ferroptosis-related genes for clinical and biological significance in hepatocellular carcinoma.
Crosstalk between the JAK2 and TGF-β1 signaling pathways in scleroderma-related interstitial lung disease targeted by baricitinib.
SDMA attenuates renal tubulointerstitial fibrosis through inhibition of STAT4.
Gene expression of TRPMLs and its regulation by pathogen stimulation.
Discovery of 4-oxo-4,5-dihydropyrazolo[1,5-a]quinoxaline-7-carboxamide derivatives as PI3Kα inhibitors via virtual screening and docking-based structure optimization.
Melatonin ameliorates acute lung injury caused by paraquat poisoning by promoting PINK1 and BNIP3 expression.
Suppression of SIRT1/FXR signaling pathway contributes to oleanolic acid-induced liver injury.
Guanine nucleotide exchange factor T exerts the cancer-promoting function in cholangiocarcinoma by enhancing the Wnt-GSK-3β-β-catenin cascade via regulation of Rac1/Cdc42.
LMNB1 deletion in ovarian cancer inhibits the proliferation and metastasis of tumor cells through PI3K/Akt pathway.
Quiescent Ovarian Cancer Cells Secrete Follistatin to Induce Chemotherapy Resistance in Surrounding Cells in Response to Chemotherapy.
Role of selenoprotein M knockdown in the melatonin antagonism of nickel-induced apoptosis and endoplasmic reticulum stress in mouse heart.
Interaction of Nmi and IFP35 Promotes Mutual Protein Stabilization and IRF3 and IRF7 Degradation to Suppress Type I IFN Production in Teleost Fish.
FOXA2 plays a critical role in hepatocellular carcinoma progression and lenvatinib-associated drug resistance.
The pathogenesis of common Gjb2 mutations associated with human hereditary deafness in mice.
The PI3K-Akt-mTOR pathway mediates renal pericyte-myofibroblast transition by enhancing glycolysis through HKII.
Effects of hunger on neuronal histone modifications slow aging in Drosophila.
Ethyl Gallate Inhibits Bovine Viral Diarrhea Virus by Promoting IFITM3 Expression, Lysosomal Acidification and Protease Activity.
Design, Synthesis and Antitumor Activity of 1H-indazole-3-amine Derivatives.
PRMT2 promotes RCC tumorigenesis and metastasis via enhancing WNT5A transcriptional expression.
Dysregulation of amino acid metabolism upon rapid depletion of cap-binding protein eIF4E.
Coaggregation of polyglutamine (polyQ) proteins is mediated by polyQ-tract interactions and impairs cellular proteostasis.
Lactiplantibacillus plantarum attenuates Coxsackievirus B3-induced pancreatitis through the BAX/BCL2/CASP3 signaling pathway.
Effect of Sublethal Concentrations of Metal Nanomaterials on Cell Energy Metabolism.
G Protein-Coupled Receptor 120 Mediates Host Defense against Clostridium perfringens Infection through Regulating NOD-like Receptor Family Pyrin Domain-Containing 3 Inflammasome Activation.
Elsholtzia bodinieri Vaniot ameliorated acute lung injury in mice by regulating pyroptosis, inflammation, oxidative stress and macrophage polarization.
β-Hydroxybutyric acid upregulated by Suhuang antitussive capsule ameliorates cough variant asthma through GSK3β/AMPK-Nrf2 signal axis.
Descending serotonergic modulation from rostral ventromedial medulla to spinal trigeminal nucleus is involved in experimental occlusal interference-induced chronic orofacial hyperalgesia.
Identification and validation of metabolism-related genes signature and immune infiltration landscape of rheumatoid arthritis based on machine learning.
Pharmaceutical SH2 domain-containing protein tyrosine phosphatase 2 inhibition suppresses primary and metastasized liver tumors by provoking hepatic innate immunity.
KIFC3 regulates progression of hepatocellular carcinoma via EMT and the AKT/mTOR pathway.
Mitotic DNA damage promotes chromokinesin-mediated missegregation of polar chromosomes in cancer cells.
Accumulated precursors of specific GPI-anchored proteins upregulate GPI biosynthesis with ARV1.
A regulatory circuit comprising the CBP and SIRT7 regulates FAM134B-mediated ER-phagy.
JNK-JUN-NCOA4 axis contributes to chondrocyte ferroptosis and aggravates osteoarthritis via ferritinophagy.
The role of ferroptosis mediated by Bmal1/Nrf2 in nicotine -induce injury of BTB integrity.
Role of nuclear factor of activated T Cells-1 in Sepsis-induced behavioral deficits in mice.
Cardiac-specific Trim44 knockout in rat attenuates isoproterenol-induced cardiac remodeling via inhibition of AKT/mTOR pathway.
Targeting fibrinogen-like protein 1 enhances immunotherapy in hepatocellular carcinoma.
FBXO11 amplifies type I interferon signaling to exert antiviral effects by facilitating the assemble of TRAF3-TBK1-IRF3 complex.
ZNFX1 antisense RNA1 promotes antiviral innate immune responses via modulating ZNFX1 function.
Exploring the mechanism of physcion-1-O-β-D-monoglucoside against acute lymphoblastic leukaemia based on network pharmacology and experimental validation.
NETs promote ROS production to induce human amniotic epithelial cell apoptosis via ERK1/2 signaling in spontaneous preterm birth.
VPS35 promotes cell proliferation via EGFR recycling and enhances EGFR inhibitors response in gastric cancer.
Targeting CXCL5 in Pancreatic Cancer Cells Inhibits Cancer Xenograft Growth by Reducing Proliferation and Inhibiting EMT Progression.
Thiol oxidative stress-dependent degradation of transglutaminase2 via protein S-glutathionylation sensitizes 5-fluorouracil therapy in 5-fluorouracil-resistant colorectal cancer cells.
FOXK2 affects cancer cell response to chemotherapy by promoting nucleotide de novo synthesis.
Sclerostin antibody promotes bone formation through the Wnt/β-catenin signaling pathway in femoral trochlear after patellar instability.
The Depletion of NAMPT Disturbs Mitochondrial Homeostasis and Causes Neuronal Degeneration in Mouse Hippocampus.
G3BP1 coordinates lysophagy activity to protect against compression-induced cell ferroptosis during intervertebral disc degeneration.
Knockdown of FGFR3 inhibits the proliferation, migration and invasion of intrahepatic cholangiocarcinoma.
Compound Kushen injection attenuates angiotensin II‑mediated heart failure by inhibiting the PI3K/Akt pathway.
Angiotensin receptor blockade with olmesartan alleviates brain pathology in obese OLETF rats.
Circ_0056618 enhances PRRG4 expression by competitively binding to miR-411-5p to promote the malignant progression of colorectal cancer.
RASSF1A inhibits epithelial-mesenchymal transition of gastric cancer cells by downregulating P-JNK.
Progranulin promotes proliferation, migration and invasion via the PI3K/Akt signalling pathway in a model of endometriosis.
CD44 mediates hyaluronan to promote the differentiation of human amniotic mesenchymal stem cells into chondrocytes.
Deubiquitinating enzyme USP11 promotes renal tubular cell senescence and fibrosis via inhibiting the ubiquitin degradation of TGF-β receptor II.
SZC-6, a small-molecule activator of SIRT3, attenuates cardiac hypertrophy in mice.
Glucose-mediated N-glycosylation of RPTPα affects its subcellular localization and Src activation.
BMAL1 collaborates with CLOCK to directly promote DNA double-strand break repair and tumor chemoresistance.
ZD6474 Attenuates Fibrosis and Inhibits Neovascularization in Human Pterygium by Suppressing AKT-mTOR Signaling Pathway.
Physalin A alleviates intervertebral disc degeneration via anti-inflammatory and anti-fibrotic effects.
The downregulation of HSP90-controlled CRALBP expression is associated with age-related vision attenuation.
Stabilization of nuclear β-catenin by inhibiting KDM2A mediates cerebral ischemic tolerance.
Treponema pallidum membrane protein Tp47 promotes angiogenesis through ROS-induced autophagy.
LAMP-2A ablation in hippocampal CA1 astrocytes confers cerebroprotection and ameliorates neuronal injury after global brain ischemia.
HSP90β promotes osteoclastogenesis by dual-activation of cholesterol synthesis and NF-κB signaling.
STMN2 overexpression promotes cell proliferation and EMT in pancreatic cancer mediated by WNT/β-catenin signaling.
Cancer-derived exosomal miR-375 targets DIP2C and promotes osteoblastic metastasis and prostate cancer progression by regulating the Wnt signaling pathway.
Abamectin causes cardiac dysfunction in carp via inhibiting redox equilibrium and resulting in immune inflammatory response and programmed cell death.
Identifying Protein-Protein Interactions by Proximity Biotinylation with AirID and splitAirID.
Histone acetyltransferase KAT2A modulates neural stem cell differentiation and proliferation by inducing degradation of the transcription factor PAX6.
The Rab GTPase-binding protein EHBP1L1 and its interactors CD2AP/CIN85 negatively regulate the length of primary cilia via actin remodeling.
Acetylation stabilizes the signaling protein WISP2 by preventing its degradation to suppress the progression of acute myeloid leukemia.
LOXL2 reduces 5-FU sensitivity through the Hedgehog/BCL2 signaling pathway in colorectal cancer.
N-homocysteinylation of α-synuclein promotes its aggregation and neurotoxicity.
Relationship Between Expression of microRNA and Chemotherapy Resistance in Cervical Carcinoma.
P2X7 receptor involved in antitumor activity of atractylenolide I in human cervical cancer cells.
DTX3L induced NLRP3 ubiquitination inhibit R28 cell pyroptosis in OGD/R injury.
Ectopic endometriotic stromal cells-derived lactate induces M2 macrophage polarization via Mettl3/Trib1/ERK/STAT3 signalling pathway in endometriosis.
MicroRNA-183-5p regulates TAR DNA-binding protein 43 neurotoxicity via SQSTM1/p62 in amyotrophic lateral sclerosis.
Vasoactive intestinal peptide receptor 2 signaling promotes breast cancer cell proliferation by enhancing the ERK pathway.
Fructooligosaccharides attenuate non-alcoholic fatty liver disease by remodeling gut microbiota and association with lipid metabolism.
Identification and characterization of a first-generation inhibitor of claudin-1 in colon cancer progression and metastasis.
Antiangiogenic potential of Lepista nuda extract suppressing MAPK/p38 signaling-mediated developmental angiogenesis in zebrafish and HUVECs.
Ganoapplins A and B with an unprecedented 6/6/6/5/6-fused pentacyclic skeleton from Ganoderma inhibit Tau pathology through activating autophagy.
Onychiol B attenuates lipopolysaccharide-induced inflammation via MAPK/NF-κB pathways and acute lung injury in vivo.
LncRNA SPRY4-IT1 facilitates cell proliferation and angiogenesis of glioma via the miR-101-3p/EZH2/VEGFA signaling axis.
Cyclin-dependent kinase subunit2 (CKS2) promotes malignant phenotypes and epithelial-mesenchymal transition-like process in glioma by activating TGFβ/SMAD signaling.
MARCO is a potential prognostic and immunotherapy biomarker.
ProBDNF signaling is involved in periodontitis-induced depression-like behavior in mouse hippocampus.
UVA1 irradiation attenuates collagen production via Ficz/AhR/MAPK signaling activation in scleroderma.
FGF4 improves hepatocytes ferroptosis in autoimmune hepatitis mice via activation of CISD3.
Identification of fatty acid metabolism-based molecular subtypes and prognostic signature to predict immune landscape and guide clinical drug treatment in renal clear cell carcinoma.
pNaktide mitigates inflammation-induced neuronal damage and behavioral deficits through the oxidative stress pathway.
Wumei Wan attenuates angiogenesis and inflammation by modulating RAGE signaling pathway in IBD: Network pharmacology analysis and experimental evidence.
Cimifugin suppresses type 2 airway inflammation by binding to SPR and regulating its protein expression in a non-enzymatic manner.
SIRT6 attenuates LPS-induced inflammation and apoptosis of lung epithelial cells in acute lung injury through ACE2/STAT3/PIM1 signaling.
Subacute ruminal acidosis downregulates FOXA2, changes oxidative status, and induces autophagy in the livers of dairy cows fed a high-concentrate diet.
ArfGAP3 regulates vesicle transport and glucose uptake in myoblasts.
N6-methyladenosine modified LINC00901 promotes pancreatic cancer progression through IGF2BP2/MYC axis.
SKA1 is overexpressed in laryngocarcinoma and modulates cell growth via P53 signaling pathway.
Oncogenes and Methionine Addiction of Cancer: Role of c-MYC.
A Comprehensive Analysis Revealing FBXW9 as a Potential Prognostic and Immunological Biomarker in Breast Cancer.
Naringenin Attenuates Isoprenaline-Induced Cardiac Hypertrophy by Suppressing Oxidative Stress through the AMPK/NOX2/MAPK Signaling Pathway.
PVT1 inhibition stimulates anti-tumor immunity, prevents metastasis, and depletes cancer stem cells in squamous cell carcinoma.
Ophiobolin A Covalently Targets Complex IV Leading to Mitochondrial Metabolic Collapse in Cancer Cells.
Aspergillus fumigatus hijacks human p11 to redirect fungal-containing phagosomes to non-degradative pathway.
Maternal Immune Activation Induces Adolescent Cognitive Deficits Preceded by Developmental Perturbations in Cortical Reelin Signalling.
Macrophage-derived exosomes mediate glomerular endothelial cell dysfunction in sepsis-associated acute kidney injury.
ROS-dependent palmitoylation is an obligate licensing modification for GSDMD pore formation.
Mitoguardin2 Is Associated With Hyperandrogenism and Regulates Steroidogenesis in Human Ovarian Granulosa Cells.
A nucleotide binding-independent role for γ-tubulin in microtubule capping and cell division.
Repurposing a tricyclic antidepressant in tumor and metabolism disease treatment through fatty acid uptake inhibition.
PABPN1 regulates mRNA alternative polyadenylation to inhibit bladder cancer progression.
BMAL1 Promotes Valvular Interstitial Cells' Osteogenic Differentiation through NF-κ B/AKT/MAPK Pathway.
Sertaconazole nitrate targets IDO1 and regulates the MAPK signaling pathway to induce autophagy and apoptosis in CRC cells.
A peptide encoded by lncRNA MIR7-3 host gene (MIR7-3HG) alleviates dexamethasone-induced dysfunction in pancreatic β-cells through the PI3K/AKT signaling pathway.
Discovery of novel and bioavailable histone deacetylases and cyclin-dependent kinases dual inhibitor to impair the stemness of leukemia cells.
The Wnt/β-catenin pathway regulates inflammation and apoptosis in ventilator-induced lung injury.
Cadherin-11-Interleukin-6 Signaling between Cardiac Fibroblast and Cardiomyocyte Promotes Ventricular Remodeling in a Mouse Pressure Overload-Induced Heart Failure Model.
ARNTL2 upregulation of ACOT7 promotes NSCLC cell proliferation through inhibition of apoptosis and ferroptosis.
DNAJB7 is dispensable for male fertility in mice.
Endothelial deletion of PTBP1 disrupts ventricular chamber development.
Integrated Proteomics Unveils Nuclear PDE3A2 as a Regulator of Cardiac Myocyte Hypertrophy.
Pseudorabies Virus Infection Activates the TLR-NF-κB Axis and AIM2 Inflammasome To Enhance Inflammatory Responses in Mice.
A thalamic-primary auditory cortex circuit mediates resilience to stress.
SODD Promotes Lung Cancer Tumorigenesis by Activating the PDK1/AKT and RAF/MEK/ERK Signaling.
CREB3L2-ATF4 heterodimerization defines a transcriptional hub of Alzheimer's disease gene expression linked to neuropathology.
CPT1A modulates PI3K/Akt/mTOR pathway to promote preeclampsia.
FBXW7 loss of function promotes esophageal squamous cell carcinoma progression via elevating MAP4 and ERK phosphorylation.
Tubeimoside-2 Triggers Methuosis in Hepatocarcinoma Cells through the MKK4-p38α Axis.
Comprehensive proteogenomic characterization of early duodenal cancer reveals the carcinogenesis tracks of different subtypes.
Disturbed rhythmicity of intestinal hydrogen peroxide alters gut microbial oscillations in BMAL1-deficient monkeys.
METTL16 promotes translation and lung tumorigenesis by sequestering cytoplasmic eIF4E2.
Development of FRET and Stress Granule Dual-Based System to Screen for Viral 3C Protease Inhibitors.
Voluntary Exercise to Reduce Anxiety Behaviour in Traumatic Brain Injury Shown to Alleviate Inflammatory Brain Response in Mice.
Muscle PARP1 inhibition extends lifespan through AMPKα PARylation and activation in Drosophila.
Integration of metabolomics and transcriptomics to reveal ferroptosis is involved in Tripterygium wilfordii polyglycoside tablet-induced testicular injury.
Erxian decoction alleviates cisplatin-induced premature ovarian failure in rats by reducing oxidation levels in ovarian granulosa cells.
Mutation at the Site of Hydroxylation in the Ribosomal Protein uL15 (RPL27a) Causes Specific Changes in the Repertoire of mRNAs Translated in Mammalian Cells.
Inhibition of miR-4640-5p alleviates pulmonary hypertension in chronic obstructive pulmonary disease patients by regulating nitric oxide synthase 1.
CCNE1 is a predictive and immunotherapeutic indicator in various cancers including UCEC: a pan-cancer analysis.
The OTUD1-Notch2-ICD axis orchestrates allogeneic T cell-mediated graft-versus-host disease.
Pan-cancer analysis of PCAT6 and its effect on oesophageal squamous cell carcinoma cell proliferation and migration.
The short isoform of MS4A7 is a novel player in glioblastoma microenvironment, M2 macrophage polarization, and tumor progression.
The Slingshot phosphatase 2 is required for acrosome biogenesis during spermatogenesis in mice.
LIFR recruits HGF-producing neutrophils to promote liver injury repair and regeneration.
Protocol for the identification and expression analysis of a cytoplasmic membrane-localized protein STING.
TUBA1C: a new potential target of LncRNA EGFR-AS1 promotes gastric cancer progression.
Overexpression of YEATS2 Remodels the Extracellular Matrix to Promote Hepatocellular Carcinoma Progression via the PI3K/AKT Pathway.
Effects of Spatial Expression of Activating Transcription Factor 4 on the Pathogenicity of Two Phenotypes of Bovine Viral Diarrhea Virus by Regulating the Endoplasmic Reticulum-Mediated Autophagy Process.
Bone Marrow Mesenchymal Stem Cells-Derived miR-21-5p Protects Grafted Islets Against Apoptosis by Targeting PDCD4.
Cuproptosis-Related Gene DLAT as a Novel Biomarker Correlated with Prognosis, Chemoresistance, and Immune Infiltration in Pancreatic Adenocarcinoma: A Preliminary Study Based on Bioinformatics Analysis.
Valproic acid inhibits cell growth in both MCF-7 and MDA-MB231 cells by triggering different responses in a cell type-specific manner.
Vacuolar protein sorting 35 (VPS35) acts as a tumor promoter via facilitating cell cycle progression in pancreatic ductal adenocarcinoma.
The structural flexibility of MAD1 facilitates the assembly of the Mitotic Checkpoint Complex.
Acute liver steatosis translationally controls the epigenetic regulator MIER1 to promote liver regeneration in a study with male mice.
Inducing primary brainstem gliomas in genetically engineered mice using RCAS/TVA retroviruses and Cre/loxP recombination.
PPT1 regulation of HSP90α depalmitoylation participates in the pathogenesis of hyperandrogenism.
Elucidation of OSW-1-Induced Stress Responses in Neuro2a Cells.
Nutrient deprivation alters the rate of COPII coat assembly to tune secretory protein transport.
Reduced SUMOylation of Nrf2 signaling contributes to its inhibition induced by amyloid-β.
High Expression of COA6 Is Related to Unfavorable Prognosis and Enhanced Oxidative Phosphorylation in Lung Adenocarcinoma.
PRAME Promotes Cervical Cancer Proliferation and Migration via Wnt/β-Catenin Pathway Regulation.
Intraduodenal Delivery of Exosome-Loaded SARS-CoV-2 RBD mRNA Induces a Neutralizing Antibody Response in Mice.
Curcumol suppresses endothelial-to-mesenchymal transition via inhibiting the AKT/GSK3β signaling pathway and alleviates pulmonary arterial hypertension in rats.
Identification of a novel missense SCN5A mutation in a Chinese Han family with Brugada syndrome.
Increased Cellular Expression of Interleukin-6 in Patients With Ossification of the Posterior Longitudinal Ligament.
HMGB1 coordinates with Brahma-related gene 1 to promote epithelial-mesenchymal transition via the PI3K/Akt/mTOR pathway in BEAS-2B cells.
Environmentally relevant perinatal exposure to DBP accelerated spermatogenesis by promoting the glycolipid metabolism of Sertoli cells in male offspring mice.
TFE3-mediated impairment of lysosomal biogenesis and defective autophagy contribute to fluoride-induced hepatotoxicity.
Discovery of unglycosylated indolocarbazoles as ROCK2 isoform-selective inhibitors for the treatment of breast cancer metastasis.
RIG-I Promotes Tumorigenesis and Confers Radioresistance of Esophageal Squamous Cell Carcinoma by Regulating DUSP6.
Shared Genes of PPARG and NOS2 in Alzheimer's Disease and Ulcerative Colitis Drive Macrophages and Microglia Polarization: Evidence from Bioinformatics Analysis and Following Validation.
Characterization of RNA G-quadruplexes in porcine epidemic diarrhea virus genome and the antiviral activity of G-quadruplex ligands.
A novel gene therapy for methamphetamine- induced cognitive disorder with a hyper-acidified fusion variant of DnaJB1.
Apigenin reduces the suppressive effect of exosomes derived from irritable bowel syndrome patients on the autophagy of human colon epithelial cells by promoting ATG14.
Autophagy Function and Benefits of Autophagy Induction in Models of Spinocerebellar Ataxia Type 3.
IFIT2 Depletion Promotes Cancer Stem Cell-like Phenotypes in Oral Cancer.
Vascular Endothelial Growth Factor A Contributes to Increased Mammalian Respiratory Epithelial Permeability Induced by Pasteurella multocida Infection.
PCGEM1 promotes cell proliferation and migration in endometriosis by targeting miR-124-3p-mediated ANTXR2 expression.
Homeobox D9 drives the malignant phenotypes and enhances the Programmed death ligand-1 expression in non-small cell lung cancer cells via binding to Angiopoietin-2 promoter.
The cellular and KSHV A-to-I RNA editome in primary effusion lymphoma and its role in the viral lifecycle.
Maslinic Acid Supplementation during the In Vitro Culture Period Ameliorates Early Embryonic Development of Porcine Embryos by Regulating Oxidative Stress.
P53 Deficiency Accelerate Esophageal Epithelium Intestinal Metaplasia Malignancy.
Hypoxia-Induced Kidney Injury in Newborn Rats.
Stratification and therapeutic potential of ELL in cytogenetic normal acute myeloid leukemia.
ROS generation and p-38 activation contribute to montmorillonite-induced corneal toxicity in vitro and in vivo.
Structure optimization and discovery of novel compound for the treatment of insertion mutations within exon 20 of EGFR and HER2.
Time-Course Transcriptomic Analysis Reveals the Crucial Roles of PANoptosis in Fungal Keratitis.
USP1/UAF1-Stabilized METTL3 Promotes Reactive Astrogliosis and Improves Functional Recovery after Spinal Cord Injury through m(6)A Modification of YAP1 mRNA.
Effects and mechanisms of Xiaochaihu Tang against liver fibrosis: An integration of network pharmacology, molecular docking and experimental validation.
Experimental study of miR-503 regulating the activity as well as the function of degenerated human nucleus pulposus cells of the intervertebral disc through inhibiting Wnt pathway.
FtMt reduces oxidative stress-induced trophoblast cell dysfunction via the HIF-1α/VEGF signaling pathway.
USP39 Regulates NF-κB-Mediated Inflammatory Responses through Deubiquitinating K48-Linked IκBα.
Polydatin Alleviates Chronic Stress-Induced Depressive and Anxiety-like Behaviors in a Mouse Model.
Disease-associated mutations in WDR34 lead to diverse impacts on the assembly and function of dynein-2.
The tick saliva peptide HIDfsin2 promotes the tick-borne virus SFTSV replication in vitro by enhancing p38 signal pathway.
PACT inhibits the replication of SARS-CoV-2 through the blockage of GSK-3β-N-nsp3 cascade.
Preterm birth alters the feeding-induced activation of Akt signaling in the muscle of neonatal piglets.
M6A modification promotes blood-brain barrier breakdown during cerebral ischemia/reperfusion injury through increasing matrix metalloproteinase 3 expression.
Benzylisoquinoline alkaloids inhibit lung fibroblast activation mainly via inhibiting TGF-β1/Smads and ERK1/2 pathway proteins.
Preoperative fibrinogen is associated with the clinical survival of primary liver cancer patients and promotes hepatoma metastasis via the PTEN/AKT/mTOR pathway.
Cinepazide maleate promotes recovery from spinal cord injury by inhibiting inflammation and prolonging neuronal survival.
Role of histone deacetylase 9 in human periodontal ligament stem cells autophagy in a tumour necrosis factor α-induced inflammatory environment.
Protective effects of electroacupuncture on polycystic ovary syndrome in rats: Down-regulating Alas2 to inhibit apoptosis, oxidative stress, and mitochondrial dysfunction in ovarian granulosa cells.
8-methoxypsoralen protects against acetaminophen-induced liver injury by antagonising Cyp2e1 in mice.
Tumor-derived extracellular vesicles delivering TNF-α promotes colorectal cancer metastasis via the NF-kB/LAMB3/AKT axis by targeting SNAP23.
Small peptide LINC00511-133aa encoded by LINC00511 regulates breast cancer cell invasion and stemness through the Wnt/β-catenin pathway.
UTP11 deficiency suppresses cancer development via nucleolar stress and ferroptosis.
Accumulated cholesterol protects tumours from elevated lipid peroxidation in the microenvironment.
ROS promote hyper-methylation of NDRG2 promoters in a DNMTS-dependent manner: Contributes to the progression of renal fibrosis.
Extracellular CIRP Induces Calpain Activation in Neurons via PLC-IP(3)-Dependent Calcium Pathway.
Ndufa4 Regulates the Proliferation and Apoptosis of Neurons via miR-145a-5p/Homer1/Ccnd2.
The MIR34B/C genomic region contains multiple potential regulators of multiciliogenesis.
STAT2/Caspase3 in the diagnosis and treatment of psoriasis.
Blocking Two-Pore Domain Potassium Channel TREK-1 Inhibits the Activation of A1-Like Reactive Astrocyte Through the NF-κB Signaling Pathway in a Rat Model of Major Depressive Disorder.
Chlorogenic Acid Alleviates Hepatic Ischemia-Reperfusion Injury by Inhibiting Oxidative Stress, Inflammation, and Mitochondria-Mediated Apoptosis In Vivo and In Vitro.
Porcupine inhibitor CGX1321 alleviates heart failure with preserved ejection fraction in mice by blocking WNT signaling.
DOCK2 Deficiency Attenuates Abdominal Aortic Aneurysm Formation-Brief Report.
Age-related Changes in Humanin Expression in the Ovarian Tissue of Rat.
ARID1A Inactivation Increases Expression of circ0008399 and Promotes Cisplatin Resistance in Bladder Cancer.
ZNF133 is a potent suppressor in breast carcinogenesis through dampening L1CAM, a driver for tumor progression.
Comprehensive landscape of TGFβ-related signature in osteosarcoma for predicting prognosis, immune characteristics, and therapeutic response.
CaMKII and Ca(V)3.2 T-type calcium channel mediate Connexin-43-dependent inflammation by activating astrocytes in vincristine-induced neuropathic pain.
Employing single valency polyphenol to prepare metal-phenolic network antitumor reagents through FeOOH assistance.
Silencing of TMED5 inhibits proliferation, migration and invasion, and enhances apoptosis of hepatocellular carcinoma cells.
Molecular basis of the TRAP complex function in ER protein biogenesis.
Microglial targeted therapy relieves cognitive impairment caused by Cntnap4 deficiency.
Protective Effect and Mechanism of Kuntai Capsule on Angiotensin II -Induced Hypertension in Ovariectomized Rats.
Acanthopanax senticosus extract alleviates radiation-induced learning and memory impairment based on neurotransmitter-gut microbiota communication.
Newcastle disease virus activates methylation-related enzymes to reprogram m(6)A methylation in infected cells.
Early activation of cellular stress and death pathways caused by cytoplasmic TDP-43 in the rNLS8 mouse model of ALS and FTD.
An mRNA processing pathway suppresses metastasis by governing translational control from the nucleus.
De novo pyrimidine biosynthetic complexes support cancer cell proliferation and ferroptosis defence.
Role of p53 in promoting BMP9‑induced osteogenic differentiation of mesenchymal stem cells through TGF‑β1.
SHCBP1 contributes to the proliferation and self‑renewal of cervical cancer cells and activation of the NF‑κB signaling pathway through EIF5A.
HnRNPAB is an independent prognostic factor in non‑small cell lung cancer and is involved in cell proliferation and metastasis.
MicroRNA26a Overexpression Hastens Osteoblast Differentiation Capacity in Dental Stem Cells.
The Role of PGK1 in Promoting Ischemia/Reperfusion Injury-Induced Microglial M1 Polarization and Inflammation by Regulating Glycolysis.
Luteolin ameliorates cornea stromal collagen degradation and inflammatory damage in rats with corneal alkali burn.
N-Acetyl-L-Cysteine Reduces Cervical Carcinogenesis by Promoting Apoptosis.
Ent-kauranes and ent-atisanes from Euphorbia wallichii and their anti-inflammatory activity.
CBX7 Rejuvenates Late Passage Dental Pulp Stem Cells by Maintaining Stemness and Pro-angiogenic Ability.
The COPS3-FOXO3 positive feedback loop regulates autophagy to promote cisplatin resistance in osteosarcoma.
Co-targeting of ACK1 and KIT triggers additive anti-proliferative and -migration effects in imatinib-resistant gastrointestinal stromal tumors.
Charged multivesicular body protein 2B ameliorates biliary injury in the liver from donation after cardiac death rats via autophagy with air-oxygenated normothermic machine perfusion.
5'-tiRNA-Gln inhibits hepatocellular carcinoma progression by repressing translation through the interaction with eukaryotic initiation factor 4A-I.
Protective effects of methylprednisolone-cyclophosphamide treatment on bleomycin-induced pulmonary fibrosis.
COUP-TFII plays a role in cAMP-induced Schwann cell differentiation and in vitro myelination by up-regulating Krox20.
Tetramethylpyrazine-Rhein Derivative inhibits the migration of canine inflammatory mammary carcinoma cells by mitochondrial damage-mediated apoptosis and cadherins downregulation.
Liensinine prevents ischemic injury following myocardial infarction via inhibition of Wnt/β‑catenin signaling activation.
NHWD-1062 ameliorates inflammation and proliferation by the RIPK1/NF-κB/TLR1 axis in Psoriatic Keratinocytes.
Senomorphic effect of diphenyleneiodonium through AMPK/MFF/DRP1 mediated mitochondrial fission.
Sitagliptin inhibits the survival, stemness and autophagy of glioma cells, and enhances temozolomide cytotoxicity.
A comprehensive analysis of single-cell RNA transcriptome reveals unique SPP1+ chondrocytes in human osteoarthritis.
Folate metabolism negatively regulates OAS-mediated antiviral innate immunity via ADAR3/endogenous dsRNA pathway.
Hedgehog pathway orchestrates the interplay of histone modifications and tailors combination epigenetic therapies in breast cancer.
PES1 is a biomarker of head and neck squamous cell carcinoma and is associated with the tumor microenvironment.
Stevioside protects primary articular chondrocytes against IL-1β-induced inflammation and catabolism by targeting integrin.
Nuciferine improves random skin flap survival via TFEB-mediated activation of autophagy-lysosomal pathway.
Isobavachalcone ameliorates the progression of osteoarthritis by suppressing NF-κB signaling pathway.
Vitamin D receptor regulates transcription of mitochondrial DNA and directly interacts with mitochondrial DNA and TFAM.
In vivo CRISPR screens identify RhoV as a pro-metastasis factor of triple-negative breast cancer.
Differences in p38-STAT3-S100A11 signaling after the administration of aristolochic acid I and IVa may account for the disparity in their nephrotoxicity.
Moshen granule ameliorates membranous nephropathy by blocking intrarenal renin-angiotensin system signalling via the Wnt1/β-catenin pathway.
Gβγ signaling regulates microtubule-dependent control of Golgi integrity.
Intrahippocampal injection of IL-1β upregulates Siah1-mediated degradation of synaptophysin by activation of the ERK signaling in male rat.
Remodeling Collagen Microenvironment in Liver Using a Biomimetic Nano-Regulator for Reversal of Liver Fibrosis.
New Cases and Mutations in SEC23B Gene Causing Congenital Dyserythropoietic Anemia Type II.
SLC35E1 promotes keratinocyte proliferation in psoriasis by regulating zinc homeostasis.
Syk-dependent alternative homologous recombination activation promotes cancer resistance to DNA targeted therapy.
SIRT1 Activator E1231 Alleviates Nonalcoholic Fatty Liver Disease by Regulating Lipid Metabolism.
Low-intensity focused ultrasound ameliorates depression-like behaviors associated with improving the synaptic plasticity in the vCA1-mPFC pathway.
tsRNA-04002 alleviates intervertebral disk degeneration by targeting PRKCA to inhibit apoptosis of nucleus pulposus cells.
Pien-Tze-Huang prevents hepatocellular carcinoma by inducing ferroptosis via inhibiting SLC7A11-GSH-GPX4 axis.
Gastroprotective effects of ginsenoside Rh4 against ethanol-induced gastric mucosal injury by inhibiting the MAPK/NF-κB signaling pathway.
ZIM1 Combined with Hydrogel Inhibits Senescence of Primary PαS Cells during In Vitro Expansion.
Identification of the E2F1-RAD51AP1 axis as a key factor in MGMT-methylated GBM TMZ resistance.
Allele-specific gene-editing approach for vision loss restoration in RHO-associated retinitis pigmentosa.
Selenoproteins synergistically protect porcine skeletal muscle from oxidative damage via relieving mitochondrial dysfunction and endoplasmic reticulum stress.
Isoproterenol pre-treatment improve the therapeutic efficacy of cardiosphere-derived cells transplantation for myocardial infarction.
AAV9-Tspyl2 gene therapy retards bleomycin-induced pulmonary fibrosis by modulating downstream TGF-β signaling in mice.
Role of Enzymic Antioxidants in Mediating Oxidative Stress and Contrasting Wound Healing Capabilities in Oral Mucosal/Skin Fibroblasts and Tissues.
DnaJC7 specifically regulates tau seeding.
Kremen2 drives the progression of non-small cell lung cancer by preventing SOCS3-mediated degradation of EGFR.
Amelioration of olfactory dysfunction in a mouse model of Parkinson's disease via enhancing GABAergic signaling.
FAK inhibitor PF-562271 inhibits the migration and proliferation of high-grade serous ovarian cancer cells through FAK and FAK mediated cell cycle arrest.
Calcium/calmodulin dependent protein kinase IV in trophoblast cells under insulin resistance: functional and metabolomic analyses.
Paradoxical Induction of ALOX15/15B by Cortisol in Human Amnion Fibroblasts: Implications for Inflammatory Responses of the Fetal Membranes at Parturition.
Du Huo Ji Sheng Tang inhibits Notch1 signaling and subsequent NLRP3 activation to alleviate cartilage degradation in KOA mice.
DUSP10 is a novel immune-related biomarker connected with survival and cellular proliferation in lower-grade glioma.
METTL14 regulates chromatin bivalent domains in mouse embryonic stem cells.
Salvianolic Acid C Inhibits the Epithelial-Mesenchymal Transition and Ameliorates Renal Tubulointerstitial Fibrosis.
High glucose promotes the progression of colorectal cancer by activating the BMP4 signaling and inhibited by glucagon-like peptide-1 receptor agonist.
Tumor-Associated Fibroblast-Derived Exosomal circDennd1b Promotes Pituitary Adenoma Progression by Modulating the miR-145-5p/ONECUT2 Axis and Activating the MAPK Pathway.
TRIM29 hypermethylation drives esophageal cancer progression via suppression of ZNF750.
The transcription factor Stat-1 is essential for Schwann cell differentiation, myelination and myelin sheath regeneration.
EZH2 Gene Knockdown Inhibits Sheep Pituitary Cell Proliferation via Downregulating the AKT/ERK Signaling Pathway.
Sp1 Upregulation Bolsters the Radioresistance of Glioblastoma Cells by Promoting Double Strand Breaks Repair.
Pharmacologic inhibition of IL11/STAT3 signaling increases MHC-I expression and T cell infiltration.
ATB(0,+)-targeted nanoparticles initiate autophagy suppression to overcome chemoresistance for enhanced colorectal cancer therapy.
Homocysteine induces ferroptosis in endothelial cells through the systemXc(-)/GPX4 signaling pathway.
Role of liensinine in sensitivity of activated macrophages to ferroptosis and in acute liver injury.
Engineered circular guide RNAs boost CRISPR/Cas12a- and CRISPR/Cas13d-based DNA and RNA editing.
"Biqi" Bayberry Extract Promotes Skeletal Muscle Fiber Type Remodeling by Increasing Fast Myofiber Formation via the Akt/FoxO1 Pathway in Mice.
ATXN3 promotes prostate cancer progression by stabilizing YAP.
Maternal NAT10 orchestrates oocyte meiotic cell-cycle progression and maturation in mice.
Differential and substrate-specific inhibition of γ-secretase by the C-terminal region of ApoE2, ApoE3, and ApoE4.
Macrophage Dectin-1 mediates Ang II renal injury through neutrophil migration and TGF-β1 secretion.
[Lipopolysaccharide stimulates macrophages to secrete exosomes containing miR-155-5p to promote activation and migration of hepatic stellate cells].
METTL16 promotes glycolytic metabolism reprogramming and colorectal cancer progression.
Panax notoginseng alleviates oxidative stress through miRNA regulations based on systems biology approach.
ULK1-mediated metabolic reprogramming regulates Vps34 lipid kinase activity by its lactylation.
The m6A Reader YTHDF2 Promotes Bladder Cancer Progression by Suppressing RIG-I-Mediated Immune Response.
Efficient and Specific Generation of MSTN-Edited Hu Sheep Using C-CRISPR.
Decapping factor Dcp2 controls mRNA abundance and translation to adjust metabolism and filamentation to nutrient availability.
EBV-Upregulated B7-H3 Inhibits NK cell-Mediated Antitumor Function and Contributes to Nasopharyngeal Carcinoma Progression.
Regulon analysis identifies protective FXR and CREB5 in proximal tubules in early diabetic kidney disease.
SETD7 promotes lateral plate mesoderm formation by modulating the Wnt/β-catenin signaling pathway.
Inflammation conditional genome editing mediated by the CRISPR-Cas9 system.
Zhx2 maintains islet β-cell mass and function by transcriptionally regulating Pax6.
m(6)A Regulates the Stability of Cellular Transcripts Required for Efficient KSHV Lytic Replication.
TOPK promotes the growth of esophageal cancer in vitro and in vivo by enhancing YB1/eEF1A1 signal pathway.
Aminosalicylates target GPR35, partly contributing to the prevention of DSS-induced colitis.
Thorium(IV) triggers ferroptosis through disrupting iron homeostasis and heme metabolism in the liver following oral ingestion.
Berberine attenuates liver fibrosis by autophagy inhibition triggering apoptosis via the miR-30a-5p/ATG5 axis.
Effects of Follicular Fluid on Physiological Characteristics and Differentiation of Fallopian Tube Epithelial Cells Implicating for Ovarian Cancer Pathogenesis.
Antidepressant effect of 4-Butyl-alpha-agarofuran via HPA axis and serotonin system.
USP1-Associated Factor 1 Modulates Japanese Encephalitis Virus Replication by Governing Autophagy and Interferon-Stimulated Genes.
Epstein-Barr Virus Envelope Glycoprotein gp110 Inhibits IKKi-Mediated Activation of NF-κB and Promotes the Degradation of β-Catenin.
Establishment of Continuous In Vitro Culture of Babesia gibsoni by Using VP-SFM Medium with Low-Concentration Serum.
LncRNA ZNF593-AS alleviates diabetic cardiomyopathy via suppressing IRF3 signaling pathway.
TNF-α activates RELA expression via TNFRSF1B to upregulate OPA1 expression and inhibit chondrogenic differentiation of human adipose stem cells.
LSM2 is associated with a poor prognosis and promotes cell proliferation, migration, and invasion in skin cutaneous melanoma.
USP8 positively regulates hepatocellular carcinoma tumorigenesis and confers ferroptosis resistance through β-catenin stabilization.
Methionine restriction promotes cGAS activation and chromatin untethering through demethylation to enhance antitumor immunity.
Traditional Chinese Medicine Danzhi qing'e decoction inhibits inflammation-associated prostatic hyperplasia via inactivation of ERK1/2 signal pathway.
Melatonin enhances anti-tumor immunity by targeting macrophages PD-L1 via exosomes derived from gastric cancer cells.
LncRNA JPX targets SERCA2a to mitigate myocardial ischemia/reperfusion injury by binding to EZH2.
A Noncoding A-to-U Kozak Site Change Related to the High Transmissibility of Alpha, Delta, and Omicron VOCs.
An alternative mechanism for skeletal muscle dysfunction in long-term post-viral lung disease.
Dapagliflozin delays renal fibrosis in diabetic kidney disease by inhibiting YAP/TAZ activation.
A Tumor-suppressive Molecular Axis EP300/circRERE/miR-6837-3p/MAVS Activates Type I IFN Pathway and Antitumor Immunity to Suppress Colorectal Cancer.
The ovarian-related effects of polystyrene nanoplastics on human ovarian granulosa cells and female mice.
CM3-SII polysaccharide obtained from Cordyceps militaris ameliorates hyperlipidemia in heterozygous LDLR-deficient hamsters by modulating gut microbiota and NPC1L1 and PPARα levels.
Tissue-resident CXCR4(+) macrophage as a poor prognosis signature promotes pancreatic ductal adenocarcinoma progression.
Exercise Improves Metabolism and Alleviates Atherosclerosis via Muscle-Derived Extracellular Vesicles.
Long noncoding RNA HITT coordinates with RGS2 to inhibit PD-L1 translation in T cell immunity.
Prematurity blunts protein synthesis in skeletal muscle independently of body weight in neonatal pigs.
Cortactin contributes to the tumorigenesis of gastric cancer by activating ERK/MMP pathway.
Identification of ALG3 as a potential prognostic biomarker in lung adenocarcinoma.
Identification of pathogenic deep intronic variant and exonic LINE-1 insertion in a patient with Meckel syndrome.
An iRGD-conjugated photothermal therapy-responsive gold nanoparticle system carrying siCDK7 induces necroptosis and immunotherapeutic responses in lung adenocarcinoma.
STING deficiency protects against wasp venom-induced acute kidney injury.
Natural Oncolysis of Enterovirus 71 in Antitumor Therapy of Colorectal Cancer.
Zinc finger E-box binding homebox 2 alleviated experimental osteoarthritis in rats.
Activated KRAS reprograms neural progenitor cells to glioma stem cell‑like phenotype.
Histone lysine demethylase 3B regulates autophagy via transcriptional regulation of GABARAPL1 in acute myeloid leukemia cells.
Deficiency of S100 calcium binding protein A9 attenuates vascular dysfunction in aged mice.
A framework for individualized splice-switching oligonucleotide therapy.
PLSCR1 is a cell-autonomous defence factor against SARS-CoV-2 infection.
GDF11, a target of miR-32-5p, suppresses high-glucose-induced mitochondrial dysfunction and apoptosis in HK-2 cells through PI3K/AKT signaling activation.
RNA-binding Protein QKI Inhibits Osteogenic Differentiation Via Suppressing Wnt Pathway.
Protoporphyrin IX-loaded albumin nanoparticles reverse cancer chemoresistance by enhancing intracellular reactive oxygen species.
Synergistic effect of elevated glucose levels with SARS-CoV-2 spike protein induced NOX-dependent ROS production in endothelial cells.
STAT4, a potential predictor of prognosis, promotes CD8 T‑cell infiltration in ovarian serous carcinoma by inducing CCL5 secretion.
Metformin synergistically enhances the antitumour activity of Lenvatinib in hepatocellular carcinoma by altering AKT-FOXO3 signalling pathway.
Autophagy-related gene PXN as a prognostic marker: Promotion of ovarian cancer progression by suppressing the p110β/Vps34/Beclin1 pathway.
Circular forms of dedicator of cytokinesis 1 promotes breast cancer progression by derepressing never in mitosis related kinase 2 via sponging miR-128-3p.
Nucleolar protein treacle ribosome biogenesis factor 1 maintains gastric cancer cell proliferation by regulating R-loop associated DNA replication stress.
The day-night differences in cognitive and anxiety-like behaviors of mice after chronic sleep restriction.
A mitochondria-targeting ROS-activated nanoprodrug for self-augmented antitumor oxidation therapy.
The deubiquitinase USP28 maintains the expression of the transcription factor MYCN and is essential in neuroblastoma cells.
Porcine reproductive and respiratory syndrome virus infection inhibits NF-κB signaling pathway through cleavage of IKKβ by Nsp4.
Combination therapy with BMSCs‑exosomes and porous tantalum for the repair of femur supracondylar defects.
Transmembrane nuclease NUMEN/ENDOD1 regulates DNA repair pathway choice at the nuclear periphery.
Matrix metalloproteinases are key targets of acupuncture in the treatment of ulcerative colitis.
The inhibitory effect of vitamin D on myocardial homocysteine levels involves activation of Nrf2-mediated methionine synthase.
m6A Modification Mediates Exosomal LINC00657 to Trigger Breast Cancer Progression Via Inducing Macrophage M2 Polarization.
Islet amyloid polypeptide triggers α-synuclein pathology in Parkinson's disease.
Anisomycin inhibits Coxsackievirus B replication by promoting the lysosomal degradation of eEF1A1.
Harringtonine: A more effective antagonist for Omicron variant.
SIRT3-mediated autophagy contributes to ferroptosis-induced anticancer by inducing the formation of BECN1-SLC7A11 complex.
Neotuberostemonine and tuberostemonine ameliorate pulmonary fibrosis through suppressing TGF-β and SDF-1 secreted by macrophages and fibroblasts via the PI3K-dependent AKT and ERK pathways.
Dexmedetomidine Suppresses Glutamate-Stimulated Neuronal Injury Via MicroRNA-433/Janus Kinase 2/Signal Transducer and Activator of Transcription 3 Pathway.
Targeting ABCB6 with nitidine chloride inhibits PI3K/AKT signaling pathway to promote ferroptosis in multiple myeloma.
UBQLN1 deficiency mediates telomere shortening and IPF through interacting with RPA1.
hUMSCs Transplantation Regulates AMPK/NR4A1 Signaling Axis to Inhibit Ovarian Fibrosis in POI Rats.
Upregulation of CDGSH iron sulfur domain 2 attenuates cerebral ischemia/reperfusion injury.
Combined exposure to lead and high-fat diet induced neuronal deficits in rats: Anti-neuroinflammatory role of SIRT1.
The bound polyphenols of foxtail millet (Setaria italica) inner shell inhibit breast cancer by promoting lipid accumulation-induced autophagic death.
Integration of proteomics and network toxicology reveals the mechanism of mercury chloride induced hepatotoxicity, in mice and HepG2 cells.
Liensinine, a alkaloid from lotus plumule, mitigates lipopolysaccharide-induced sepsis-associated encephalopathy through modulation of nuclear factor erythroid 2-related factor-mediated inflammatory biomarkers and mitochondria apoptosis.
Single-cell sequencing analysis reveals development and differentiation trajectory of Schwann cells manipulated by M. leprae.
Astragalus polysaccharide ameliorated complex factor-induced chronic fatigue syndrome by modulating the gut microbiota and metabolites in mice.
Xanthotoxin, a novel inducer of platelet formation, promotes thrombocytopoiesis via IL-1R1 and MEK/ERK signaling.
Nobiletin alleviates myocardial ischemia-reperfusion injury via ferroptosis in rats with type-2 diabetes mellitus.
Vitamin B12 alleviates myocardial ischemia/reperfusion injury via the SIRT3/AMPK signaling pathway.
Analysis and Validation of TMED3 correlates with poor prognosis and tumor immune infiltration of glioma.
Extracellular vesicles derived from hypoxic HTR-8/SVneo trophoblast inhibit endothelial cell functions through the miR-150-3p /CHPF pathway.
CRIP1 supports the growth and migration of AML-M5 subtype cells by activating Wnt/β-catenin pathway.
RIPK3-MLKL necroptotic signalling amplifies STING pathway and exacerbates lethal sepsis.
Dissecting the effect of ileal faecal diversion on the intestine using single-cell sequencing.
Single-cell landscape analysis reveals systematic senescence in mammalian Down syndrome.
Dipeptidyl peptidase 3 is essential for maintaining osteoblastic differentiation under a high-glucose environment by inhibiting apoptosis, oxidative stress and inflammation through the modulation of the Keap1-Nrf2 pathway.
Aloperine alleviates lipopolysaccharide-induced acute lung injury by inhibiting NLRP3 inflammasome activation.
l-Arginine-Modified CoWO(4) /FeWO(4) S-Scheme Heterojunction Enhances Ferroptosis against Solid Tumor.
Inhibition of FGFR3 upregulates MHC-I and PD-L1 via TLR3/NF-kB pathway in muscle-invasive bladder cancer.
COLEC10 Induces Endoplasmic Reticulum Stress by Occupying GRP78 and Inhibits Hepatocellular Carcinoma.
RNA-seq analysis reveals candidate genes associated with proliferation, invasion, and migration in BCL11A knockdown B-NHL cell lines.
Ultrasound Responsive Nanovaccine Armed with Engineered Cancer Cell Membrane and RNA to Prevent Foreseeable Metastasis.
Alleviation of Limosilactobacillus reuteri in polycystic ovary syndrome protects against circadian dysrhythmia-induced dyslipidemia via capric acid and GALR1 signaling.
Targeting macrophagic PIM-1 alleviates osteoarthritis by inhibiting NLRP3 inflammasome activation via suppressing mitochondrial ROS/Cl(-) efflux signaling pathway.
The Extract of Scutellaria baicalensis Attenuates the Pattern Recognition Receptor Pathway Activation Induced by Influenza A Virus in Macrophages.
VDR alleviates endothelial cell injury in arteriovenous fistula through inhibition of P66Shc-mediated mitochondrial ROS.
Ferrostatin-1 alleviates the damage of C2C12 myoblast and mouse pelvic floor muscle induced by mechanical trauma.
Aberrant mechanical loading induces annulus fibrosus cells apoptosis in intervertebral disc degeneration via mechanosensitive ion channel Piezo1.
Proximity Proteomics and Biochemical Analysis Reveal a Noncanonical Function for UFM1-Specific Protease 1 in the p62 Body Formation.
Higher expression of pseudouridine synthase 7 promotes non-small cell lung cancer progression and suggests a poor prognosis.
PARP1 negatively regulates transcription of BLM through its interaction with HSP90AB1 in prostate cancer.
Cooperative sensing of mitochondrial DNA by ZBP1 and cGAS promotes cardiotoxicity.
The translational landscape of human vascular smooth muscle cells identifies novel short open reading frame-encoded peptide regulators for phenotype alteration.
The protective effects of sophocarpine on sepsis-induced cardiomyopathy.
5-Azacytidine promotes HCC cell metastasis by up-regulating RDH16 expression.
SGLT2 inhibitor dapagliflozin alleviates intramyocardial hemorrhage and adverse ventricular remodeling via suppressing hepcidin in myocardial ischemia-reperfusion injury.
Jujuboside A ameliorates cognitive deficiency in delirium through promoting hippocampal E4BP4 in mice.
BMP2 induces osteogenic differentiation through ACKR3 in mesenchymal stem cells.
P2X7 receptor-mediated depression-like reactions arising in the mouse medial prefrontal cortex.
GBAP1 functions as a tumor promotor in hepatocellular carcinoma via the PI3K/AKT pathway.
A novel polypeptide CAPG-171aa encoded by circCAPG plays a critical role in triple-negative breast cancer.
Downregulation of BASP1 Promotes Temozolomide Resistance in Gliomas via Epigenetic Activation of the FBXO32/NF-κB/MGMT Axis.
The role of TOP2A in immunotherapy and vasculogenic mimicry in non-small cell lung cancer and its potential mechanism.
IL-33/ST2 axis of human amnion fibroblasts participates in inflammatory reactions at parturition.
LncRNA LZTS1-AS1 induces proliferation, metastasis and inhibits autophagy of pancreatic cancer cells through the miR-532 /TWIST1 signaling pathway.
Macrophage lineage cells-derived migrasomes activate complement-dependent blood-brain barrier damage in cerebral amyloid angiopathy mouse model.
MAT as a promising therapeutic strategy against triple-negative breast cancer via inhibiting PI3K/AKT pathway.
Tanshinone I specifically suppresses NLRP3 inflammasome activation by disrupting the association of NLRP3 and ASC.
Disruption of RCAN1.4 expression mediated by YY1/HDAC2 modulates chronic renal allograft interstitial fibrosis.
Modified Podophyllotoxin Phenoxyacetamide Phenylacetate Derivatives: Tubulin/AKT1 Dual-Targeting and Potential Anticancer Agents for Human NSCLC.
Intestinal Cckbr-specific knockout mouse as a novel model of salt-sensitive hypertension via sodium over-absorption.
Reduced NR2F2 Expression in the Host Response to Infectious Bursal Disease Virus Infection Suppressed Viral Replication by Enhancing Type I Interferon Expression by Targeting SOCS5.
Coreceptor AXL Facilitates African Swine Fever Virus Entry via Apoptotic Mimicry.
USP18 overexpression protects against spinal cord ischemia/reperfusion injury via regulating autophagy.
Interaction between neutrophil extracellular traps and cardiomyocytes contributes to atrial fibrillation progression.
Injectable hydrogel made from antler mesenchyme matrix for regenerative wound healing via creating a fetal-like niche.
Identification of TGF-β-related genes in cardiac hypertrophy and heart failure based on single cell RNA sequencing.
ALKBH5 causes retinal pigment epithelium anomalies and choroidal neovascularization in age-related macular degeneration via the AKT/mTOR pathway.
A MOF-Based Potent Ferroptosis Inducer for Enhanced Radiotherapy of Triple Negative Breast Cancer.
Metastasis-related gene signature associates with immunity and predicts prognosis accurately in patients with osteosarcoma.
Membrane stretch as the mechanism of activation of PIEZO1 ion channels in chondrocytes.
Kaempferol inhibits non-homologous end joining repair via regulating Ku80 stability in glioma cancer.
CD44 Is Associated with Poor Prognosis of ccRCC and Facilitates ccRCC Cell Migration and Invasion through HAS1/MMP9.
SIRT3 ameliorates diabetes-associated cognitive dysfunction via regulating mitochondria-associated ER membranes.
AAV-GRN partially corrects motor deficits and ALS/FTLD-related pathology in Tmem106b(-/-)Grn(-/-) mice.
A proximity labeling strategy enables proteomic analysis of inter-organelle membrane contacts.
Suppression of TREX1 deficiency-induced cellular senescence and interferonopathies by inhibition of DNA damage response.
Establishing SARS-CoV-2 membrane protein-specific antibodies as a valuable serological target via high-content microscopy.
Uterine-specific Ezh2 deletion enhances stromal cell senescence and impairs placentation, resulting in pregnancy loss.
Acetylation halts missense mutant p53 aggregation and rescues tumor suppression in non-small cell lung cancers.
Esaxerenone Inhibits Renal Angiogenesis and Endothelial-Mesenchymal Transition via the VEGFA and TGF-β1 Pathways in Aldosterone-Infused Mice.
JUN-induced super-enhancer RNA forms R-loop to promote nasopharyngeal carcinoma metastasis.
ZIC2 induces pro-tumor macrophage polarization in nasopharyngeal carcinoma by activating the JUNB/MCSF axis.
Integrative CRISPR Activation and Small Molecule Inhibitor Screening for lncRNA Mediating BRAF Inhibitor Resistance in Melanoma.
[MiR-30e-5p overexpression promotes proliferation and migration of colorectal cancer cells by activating the CXCL12 axis via downregulating PTEN].
QKI shuttles internal m(7)G-modified transcripts into stress granules and modulates mRNA metabolism.
Atractylenolide III Ameliorates Bile Duct Ligation-Induced Liver Fibrosis by Inhibiting the PI3K/AKT Pathway and Regulating Glutamine Metabolism.
Lnc-LRRTM4 promotes proliferation, metastasis and EMT of colorectal cancer through activating LRRTM4 transcription.
Integrative analysis of the ST6GALNAC family identifies GATA2-upregulated ST6GALNAC5 as an adverse prognostic biomarker promoting prostate cancer cell invasion.
Comparative transcriptome profiling of Eimeria tenella in various developmental stages and functional analysis of an ApiAP2 transcription factor exclusively expressed during sporogony.
Two-in-One Polymeric NO-Donor Prodrugs Mediate Precision and Synergistic Prostate Cancer Treatment.
NUMA1 modulates apoptosis of esophageal squamous cell carcinoma cells through regulating ASK1-JNK signaling pathway.
Bifidobacterium adolescentis induces Decorin(+) macrophages via TLR2 to suppress colorectal carcinogenesis.
Neuroprotective effect of a medium-chain triglyceride ketogenic diet on MPTP-induced Parkinson's disease mice: a combination of transcriptomics and metabolomics in the substantia nigra and fecal microbiome.
Ablation of the gut microbiota alleviates high-methionine diet-induced hyperhomocysteinemia and glucose intolerance in mice.
Maternal TDP-43 interacts with RNA Pol II and regulates zygotic genome activation.
SNRPD1 inhibition suppresses the proliferation of hepatocellular carcinoma and promotes autophagy through the PI3K/AKT/mTOR/4EBP1 pathway.
NAT10-mediated AXL mRNA N4-acetylcytidine modification promotes pancreatic carcinoma progression.
Schisandrin C enhances cGAS-STING pathway activation and inhibits HBV replication.
A herbal product inhibits carbon tetrachloride-induced liver fibrosis by suppressing the epidermal growth factor receptor signaling pathway.
MiR-29c-5p regulates the function of buffalo granulosa cells to induce follicular atresia by targeting INHBA.
The ototoxic drug cisplatin localises to stress granules altering their dynamics and composition.
Overexpression of POLA2 in hepatocellular carcinoma is involved in immune infiltration and predicts a poor prognosis.
Reduced Vrk2 expression is associated with higher risk of depression in humans and mediates depressive-like behaviors in mice.
Identification of a psychiatric risk gene NISCH at 3p21.1 GWAS locus mediating dendritic spine morphogenesis and cognitive function.
CDC20 Is Regulated by the Histone Methyltransferase, KMT5A, in Castration-Resistant Prostate Cancer.
Exploring Cancer Dependency Map genes and immune subtypes in colon cancer, in which TIGD1 contributes to colon cancer progression.
Cytochrome c lysine acetylation regulates cellular respiration and cell death in ischemic skeletal muscle.
N-carbamoyl aspartate reduced body weight by stimulating the thermogenesis of iBAT.
Lipopolysaccharide-induced sepsis impairs M2R-GIRK signaling in the mouse sinoatrial node.
A coordinated multiorgan metabolic response contributes to human mitochondrial myopathy.
Regulation of Sertoli cell function by planar cell polarity (PCP) protein Fjx1.
Gut microbiota contribute to Methamphetamine-induced cardiotoxicity in mouse model.
A multiparametric fluorescent visualization approach for detecting drug resistance in living cancer cells.
Lysine crotonylation of SERCA2a correlates to cardiac dysfunction and arrhythmia in Sirt1 cardiac-specific knockout mice.
Aligned lovastatin-loaded electrospun nanofibers regulate collagen organization and reduce scar formation.
Hydrogen sulfide alleviates heart failure with preserved ejection fraction in mice by targeting mitochondrial abnormalities via PGC-1α.
DNA virus oncoprotein HPV18 E7 selectively antagonizes cGAS-STING-triggered innate immune activation.
Hydrogen sulfide inhibits human T-cell leukemia virus type-1 (HTLV-1) protein expression via regulation of ATG4B.
SARS-CoV-2 ORF3a inhibits cGAS-STING-mediated autophagy flux and antiviral function.
GSK3326595 is a promising drug to prevent SARS-CoV-2 Omicron and other variants infection by inhibiting ACE2-R671 di-methylation.
Immune checkpoint PTPN2 predicts prognosis and immunotherapy response in human cancers.
Loss of Pten in Renal Tubular Cells Leads to Water Retention by Upregulating AQP2.
Immunological profiles of human oligodendrogliomas define two distinct molecular subtypes.
SIRT2 promotes cell proliferation and migration through mediating ERK1/2 activation and lactosylceramide accumulation in prostate cancer.
Overexpressed Cyclin D1 and CDK4 proteins are responsible for the resistance to CDK4/6 inhibitor in breast cancer that can be reversed by PI3K/mTOR inhibitors.
SATB1/SLC7A11/HO-1 Axis Ameliorates Ferroptosis in Neuron Cells After Ischemic Stroke by Danhong Injection.
MicroRNA profiling reveals the role of miR-133b-3p in promoting apoptosis and inhibiting cell proliferation and testosterone synthesis in mouse TM3 cells.
Actin related protein 2/3 complex subunit 1 up-regulation in the hypothalamus prevents high-fat diet induced obesity.
Site-specific ubiquitination of VDAC1 restricts its oligomerization and mitochondrial DNA release in liver fibrosis.
The Correlation between Increased Expressions of NLRP3 Inflammasome Components in Peripheral Blood Mono-Nuclear Cells and Plaque Vulnerability in Human Carotid Atherosclerosis.
Ginsenoside Rg3 liposomes regulate tumor microenvironment for the treatment of triple negative breast cancer.
Prefoldin 6 promotes glioma progression via the AKT signalling pathway.
SPARC expression in tumor microenvironment induces partial epithelial-to-mesenchymal transition of esophageal adenocarcinoma cells via cooperating with TGF-β signaling.
Imbalance in ALR ubiquitination accelerates the progression of nonalcoholic steatohepatitis to hepatocellular carcinoma.
Long non-coding RNA HOXC-AS1 exerts its oncogenic effects in esophageal squamous cell carcinoma by interaction with IGF2BP2 to stabilize SIRT1 expression.
Resveratrol reverses TGF-β1-mediated invasion and metastasis of breast cancer cells via the SIRT3/AMPK/autophagy signal axis.
M1/M2 re-polarization of kaempferol biomimetic NPs in anti-inflammatory therapy of atherosclerosis.
Attenuation of Piwil2 induced by hypoxic postconditioning prevents cerebral ischemic injury by inhibiting CREB2 promoter methylation.
Lysine-40 succinylation of TAGLN2 induces glioma angiogenesis and tumor growth through regulating TMSB4X.
Melatonin Increases Proliferation and Decreases Apoptosis of GC-1 spg Cells by Upregulating the Expression of circTec.
Ginsenoside Rg1 promotes astrocyte-to-neuron transdifferentiation in rat and its possible mechanism.
Depletion of SASH1, an astrocyte differentiation-related gene, contributes to functional recovery in spinal cord injury.
miR-27a-3p targets NR5A2 to regulate CYP19A1 expression and 17-β estradiol synthesis in ovine granulosa cells.
iPSC-based model of Vogt-Koyanagi-Harada disease for phenotype recapitulation and drug screening.
AP2S1 regulates APP degradation through late endosome-lysosome fusion in cells and APP/PS1 mice.
CCNE1 is a potential target of Metformin for tumor suppression of ovarian high-grade serous carcinoma.
A novel 3-phenylglutaric acid derivative (84-B10) alleviates cisplatin-induced acute kidney injury by inhibiting mitochondrial oxidative stress-mediated ferroptosis.
Targeting RNA G-quadruplex with repurposed drugs blocks SARS-CoV-2 entry.
Palmitic acid induces nDNA release to cytosol and promotes microglial M1 polarization via cGAS-STING signaling pathway.
RNA-binding motif 4 promotes angiogenesis in HCC by selectively activating VEGF-A expression.
Icariin ameliorates memory deficits through regulating brain insulin signaling and glucose transporters in 3×Tg-AD mice.
Reactive oxygen species-induced long intergenic noncoding RNA p21 accelerates abdominal aortic aneurysm formation by promoting secretary smooth muscle cell phenotypes.
Exposure to dithiocarbamate fungicide maneb in vitro and in vivo: Neuronal apoptosis and underlying mechanisms.
Inhibition of interaction between ROCK1 and Rubicon restores autophagy in endothelial cells and attenuates brain injury after prolonged ischemia.
CircSETD3 mediates acquired resistance to gefitinib in non-small lung cancer cells by FXR1/ECT2 pathway.
Characterization of DJ-1, PTEN, and p-Akt as Prognostic Biomarkers in the Progression of Oral Squamous Cell Carcinoma.
A hnRNPA2B1 agonist effectively inhibits HBV and SARS-CoV-2 omicron in vivo.
Effects of leptin treatment immediately after neonatal seizures on serum clusterin and VEGF levels and brain oxidative stress-related proteins and neurobehavioral phenotypes.
CgTNF-2 promotes the proliferation of haemocytes by regulating the expressions of CgRunx and cell cycle related genes in the Pacific oyster Crassostrea gigas.
Dihydrotanshinone I preconditions myocardium against ischemic injury via PKM2 glutathionylation sensitive to ROS.
Capecitabine induces hand-foot syndrome through elevated thymidine phosphorylase-mediated locoregional toxicity and GSDME-driven pyroptosis that can be relieved by tipiracil.
An In Vitro Engineered Osteochondral Model as Tool to Study Osteoarthritis Environment.
EphrinA3 is a key regulator of malignant behaviors and a potential prognostic factor in lung adenocarcinoma.
Neurogranin as an important regulator in swimming training to improve the spatial memory dysfunction of mice with chronic cerebral hypoperfusion.
Treponema pallidum lipoprotein Tp0768 promotes the migration and adhesion of THP-1 cells to vascular endothelial cells through stress of the endoplasmic reticulum and the NF-κB/HIF-1α pathway.
Molecular hydrogen attenuates sepsis-induced cognitive dysfunction through regulation of tau phosphorylation.
Protective effects of leonurine hydrochloride on pyroptosis in premature ovarian insufficiency via regulating NLRP3/GSDMD pathway.
Copper transporter gene ATP7A: A predictive biomarker for immunotherapy and targeted therapy in hepatocellular carcinoma.
The effects of taraxasterol on liver fibrosis revealed by RNA sequencing.
Treatment with butyrate alleviates dextran sulfate sodium and Clostridium difficile-induced colitis by preventing activity of Th17 cells via regulation of SIRT1/mTOR in mice.
M13, an anthraquinone compound isolated from Morinda officinalis promotes the osteogenic differentiation of MSCs by targeting Wnt/β-catenin signaling.
The mechanisms of Qizhu Tangshen formula in the treatment of diabetic kidney disease: Network pharmacology, machine learning, molecular docking and experimental assessment.
Glycocholic acid aggravates liver fibrosis by promoting the up-regulation of connective tissue growth factor in hepatocytes.
Desulfovibrio desulfuricans aggravates atherosclerosis by enhancing intestinal permeability and endothelial TLR4/NF-κB pathway in Apoe (-/-) mice.
Heparanase Contributes to Psoriatic Lesions Through Crosstalk with IL-17 Pathway.
Systemic Administration of Lipopolysaccharide from Porphyromonas gingivalis Decreases Neprilysin Expression in the Mouse Hippocampus.
Exosomes From Adipose-Derived Stem Cells Suppress the Progression of Chronic Endometritis.
Babao Dan Alleviates Cancer Cachexia in Mice Via Inhibiting IL-6/STAT3 Signaling Pathway.
Predictive Models for Colon Adenocarcinoma Diagnosis, Prognosis, and Immune Microenvironment Based on 2 Hypoxia-Related Genes: KDM3A and ENO3.
TRIM11 Posttranscriptionally Modulated by miR-5193 Facilitates Tumor Growth and Metastasis of Prostate Cancer.
MicroRNA-1205 Suppresses Hepatocellular Carcinoma Cell Proliferation via a CSNK2B/CDK4 Axis.
Exosomal-miR-129-2-3p derived from Fusobacterium nucleatum-infected intestinal epithelial cells promotes experimental colitis through regulating TIMELESS-mediated cellular senescence pathway.
Therapeutic potential of Clostridium butyricum anticancer effects in colorectal cancer.
Calcium Phosphate Bone Cements Incorporated with Black Phosphorus Nanosheets Enhanced Osteogenesis.
iTRAQ-based Proteomic Analysis Unveils ACSL4 as a Novel Potential Regulator of Human Endometrial Receptivity.
The CDK inhibitor AT7519 inhibits human glioblastoma cell growth by inducing apoptosis, pyroptosis and cell cycle arrest.
TEAD4 is a master regulator of high-risk nasopharyngeal carcinoma.
Downregulation of CEMIP enhances radiosensitivity by promoting DNA damage and apoptosis in colorectal cancer.
Mitofusin 2 mutation drives cell proliferation in Charcot-Marie-Tooth 2A fibroblasts.
Cadmium Activates EGFR/STAT5 Signaling to Overcome Calcium Chelation and Promote Epithelial to Mesenchymal Transition.
ALKBH5 prevents hepatocellular carcinoma progression by post-transcriptional inhibition of PAQR4 in an m6A dependent manner.
Baicalin prevents fibrosis of human trabecular meshwork cells via inhibiting the MyD88/NF-κB pathway.
An enhancer-based gene-therapy strategy for spatiotemporal control of cargoes during tissue repair.
Decoding m(6)A RNA methylome identifies PRMT6-regulated lipid transport promoting AML stem cell maintenance.
Fusobacterium nucleatum Extracellular Vesicles Promote Experimental Colitis by Modulating Autophagy via the miR-574-5p/CARD3 Axis.
A Mulberry Diels-Alder-Type Adduct, Kuwanon M, Triggers Apoptosis and Paraptosis of Lung Cancer Cells through Inducing Endoplasmic Reticulum Stress.
Decapping factor Dcp2 controls mRNA abundance and translation to adjust metabolism and filamentation to nutrient availability.
SIGIRR-caspase-8 signaling mediates endothelial apoptosis in Kawasaki disease.
A high-efficient and naked-eye visible CRISPR/Cas9 system in Arabidopsis.
The deubiquitinase OTUD1 noncanonically suppresses Akt activation through its N-terminal intrinsically disordered region.
The Effect of the Histone Chaperones HSPA8 and DEK on Tumor Immunity in Hepatocellular Carcinoma.
5'-tRF-GlyGCC promotes breast cancer metastasis by increasing fat mass and obesity-associated protein demethylase activity.
Effects of acupuncture on the miR-146a-mediated IRAK1/TRAF6/NF-κB signaling pathway in rats with sarcopenia induced by D-galactose.
Hypermetabolism in mice carrying a near complete human chromosome 21.
AGEs induce endothelial cells senescence and endothelial barrier dysfunction via miR-1-3p/MLCK signaling pathways.
Biejiajian pill inhibits progression of hepatocellular carcinoma by downregulating PDGFRβ signaling in cancer-associated fibroblasts.
Hordenine Activated Dermal Papilla Cells and Promoted Hair Regrowth by Activating Wnt Signaling Pathway.
Adipose-specific deletion of the cation channel TRPM7 inhibits TAK1 kinase-dependent inflammation and obesity in male mice.
LncRNA WDR11-AS1 Promotes Extracellular Matrix Synthesis in Osteoarthritis by Directly Interacting with RNA-Binding Protein PABPC1 to Stabilize SOX9 Expression.
Perinatal Fat-Diets Increased Angiotensin II-Mediated Ca(2+) through PKC-L-Type Calcium Channel Axis in Resistance Arteries via Agtr1a-Prkcb Gene Methylation.
Ginsenoside Rb1 induces autophagic lipid degradation via miR-128 targeting TFEB.
MFG-E8 stabilized by deubiquitinase USP14 suppresses cigarette smoke-induced ferroptosis in bronchial epithelial cells.
Antisense oligonucleotide therapy rescues disturbed brain rhythms and sleep in juvenile and adult mouse models of Angelman syndrome.
TMBIM4 Deficiency Facilitates NLRP3 Inflammasome Activation-Induced Pyroptosis of Trophoblasts: A Potential Pathogenesis of Preeclampsia.
Ciclopirox Inhibition of eIF5A Hypusination Attenuates Fibroblast Activation and Cardiac Fibrosis.
Development of a Novel (18)F-Labeled Probe for PET Imaging of Estrogen Receptor β.
TRIM21 attenuates renal carcinoma lipogenesis and malignancy by regulating SREBF1 protein stability.
[WITHDRAWN] Hexokinase-1 mitochondrial dissociation and protein O-GlcNAcylation drive heart failure with preserved ejection fraction.
SIRT2 inhibition protects against cardiac hypertrophy and heart failure.
LARP6 suppresses colorectal cancer progression through ZNF267/SGMS2-mediated imbalance of sphingomyelin synthesis.
Functional characterization of GATA6 genetic variants associated with mild congenital heart defects.
Antagonism among DUX family members evolved from an ancestral toxic single homeodomain protein.
Mitophagy Effects of Protodioscin on Human Osteosarcoma Cells by Inhibition of p38MAPK Targeting NIX/LC3 Axis.
Screening and identification of CNIH4 gene associated with cell proliferation in gastric cancer based on a large-scale CRISPR-Cas9 screening database DepMap.
Centrosomal protein 120 promotes centrosome amplification and gastric cancer progression via USP54-mediated deubiquitination of PLK4.
Alternative transcribed 3' isoform of long non-coding RNA Malat1 inhibits mouse retinal oxidative stress.
Marine-Derived Natural Product HDYL-GQQ-495 Targets P62 to Inhibit Autophagy.
The Adipokine Visfatin Modulates Cancer Stem Cell Properties in Triple-Negative Breast Cancer.
miR-214-5p/C1QTNF1 axis enhances PCV2 replication through promoting autophagy by targeting AKT/mTOR signaling pathway.
RPS24 Is Associated with a Poor Prognosis and Immune Infiltration in Hepatocellular Carcinoma.
REC drives recombination to repair double-strand breaks in animal mtDNA.
Hepatocyte growth factor-mediated apoptosis mechanisms of cytotoxic CD8(+) T cells in normal and cirrhotic livers.
Bacillus subtilis Modulated the Expression of Osteogenic Markers in a Human Osteoblast Cell Line.
Kaposi's sarcoma-associated herpesvirus induces specialised ribosomes to efficiently translate viral lytic mRNAs.
Driving axon regeneration by orchestrating neuronal and non-neuronal innate immune responses via the IFNγ-cGAS-STING axis.
MiR-182 Is Upregulated in Prostate Cancer and Contributes to Tumor Progression by Targeting MITF.
Proteoglycan SPOCK1 as a Poor Prognostic Marker Promotes Malignant Progression of Clear Cell Renal Cell Carcinoma via Triggering the Snail/Slug-MMP-2 Axis-Mediated Epithelial-to-Mesenchymal Transition.
Discovery of IHMT-337 as a potent irreversible EZH2 inhibitor targeting CDK4 transcription for malignancies.
Niche stiffness sustains cancer stemness via TAZ and NANOG phase separation.
CTNNAL1 enhances glucocorticoid sensitivity in HDM-induced asthma mouse model through deactivating hsp90 signaling pathway.
TBK1 Isoform Inhibits Grass Carp Reovirus Infection by Targeting the Degradation of Viral Nonstructural Proteins NS80 and NS38.
The m6A demethylase FTO promotes keloid formation by up-regulating COL1A1.
Prenatal Lipopolysaccharide Exposure Alters Hepatic Drug-Metabolizing Enzyme Expression in Mouse Offspring via Histone Modifications.
Deficit of PKHD1L1 in the dentate gyrus increases seizure susceptibility in mice.
RBM4 regulates cellular senescence via miR1244/SERPINE1 axis.
Flavivirus prM interacts with MDA5 and MAVS to inhibit RLR antiviral signaling.
New Monoterpenoid Indole Alkaloids from Tabernaemontana crassa Inhibit β-Amyloid42 Production and Phospho-Tau (Thr217).
Metabolomics Profiles Reveal New Insights of Herpes Simplex Virus Type 1 Infection.
LncRNA-TBP mediates TATA-binding protein recruitment to regulate myogenesis and induce slow-twitch myofibers.
Porphyromonas gingivalis bacteremia increases the permeability of the blood-brain barrier via the Mfsd2a/Caveolin-1 mediated transcytosis pathway.
Crizotinib Nanomicelles Synergize with Chemotherapy through Inducing Proteasomal Degradation of Mutp53 Proteins.
Silencing of circCRIM1 Drives IGF2BP1-Mediated NSCLC Immune Evasion.
Disrupted BRCA1-PALB2 interaction induces tumor immunosuppression and T-lymphocyte infiltration in HCC through cGAS-STING pathway.
Effects of apocynin on ISO-induced delayed afterdepolarizations in rat atrial myocytes and the underlying mechanisms.
Ablation of EWS-FLI1 by USP9X inhibition suppresses cancer cell growth in Ewing sarcoma.
Identification of circRNA expression profiles and the potential role of hsa_circ_0006916 in silicosis and pulmonary fibrosis.
Cnpy3(2xHA) mice reveal neuronal expression of Cnpy3 in the brain.
Role and mechanism of the p-JAK2/p-STAT3 signaling pathway in follicular development in PCOS rats.
The activated ATM/AMPK/mTOR axis promotes autophagy in response to oxidative stress-mediated DNA damage co-induced by molybdenum and cadmium in duck testes.
Large extracellular vesicles in bovine follicular fluid inhibit the apoptosis of granulosa cell and stimulate the production of steroid hormones.
Dysfunctional microRNA-144-3p/ZBTB20/ERK/CREB1 signalling pathway is associated with MK-801-induced schizophrenia-like abnormalities.
Integrated manganese (III)-doped nanosystem for optimizing photothermal ablation: Amplifying hyperthermia-induced STING pathway and enhancing antitumor immunity.
Liquiritin inhibits MRGPRX2-mediated pseudo-allergy through the PI3K/AKT and PLCγ signaling pathways.
Ribosomal protein L31 (RPL31) inhibits the proliferation and migration of gastric cancer cells.
MST4 as a novel therapeutic target for autophagy and radiosensitivity in gastric cancer.
Chronic Microcystin-LR-Induced α-Synuclein Promotes Neuroinflammation Through Activation of the NLRP3 Inflammasome in Microglia.
Intra-amniotic mesenchymal stem cell therapy improves the amniotic fluid microenvironment in rat spina bifida aperta fetuses.
Periplaneta Americana extract inhibits osteoclastic differentiation in vitro.
Early growth response 2 in the mPFC regulates mouse social and cooperative behaviors.
MicroRNA-588 regulates the invasive, migratory and vasculogenic mimicry-forming abilities of hypoxic glioma cells by targeting ROBO1.
Promoting effects of calponin 3 on the growth of diffuse large B‑cell lymphoma cells.
Novel naturally occurring autoantibodies attenuate α-synuclein pathology in a mouse model of Parkinson's disease.
Disruption of the lung-gut-brain axis is responsible for cortex damage induced by pulmonary exposure to zinc oxide nanoparticles.
PKMYT1 inhibits lung adenocarcinoma progression by abrogating AKT1 activity.
Targeting ARHGEF12 promotes neuroblastoma differentiation, MYCN degradation, and reduces tumorigenicity.
Deubiquitinating enzyme Josephin-2 stabilizes PHGDH to promote a cancer stem cell phenotype in hepatocellular carcinoma.
Corynoline ameliorates dextran sulfate sodium-induced colitis in mice by modulating Nrf2/NF-κB pathway.
14-3-3ζ inhibits maladaptive repair in renal tubules by regulating YAP and reduces renal interstitial fibrosis.
Perfluorooctane sulfonate promotes hepatic lipid accumulation and steatosis in high-fat diet mice through AMP-activated protein kinase/acetyl-CoA carboxylase (AMPK/ACC) pathway.
High Level of Ubiquitin Conjugate Enzyme E2O Indicates Poor Prognosis of Patients with Hepatocellular Carcinoma.
M2-like macrophage-derived exosomes facilitate metastasis in non-small-cell lung cancer by delivering integrin αVβ3.
Decreased thioredoxin reductase 3 expression promotes nickel-induced damage to cardiac tissue via activating oxidative stress-induced apoptosis and inflammation.
PI3K/AKT/mTOR pathway mediated-cell cycle dysregulation contribute to malignant proliferation of mouse spermatogonia induced by microcystin-leucine arginine.
Ubiquitin-specific protease 24 promotes EV71 infection by restricting K63-linked polyubiquitination of TBK1.
The functional implication of ATF6α in castration-resistant prostate cancer cells.
Renal transporter OAT1 and PPAR-α pathway co-contribute to icaritin-induced nephrotoxicity.
3, 14, 19-Triacetyl Andrographolide alleviates the cognitive dysfunction of 3 × Tg-AD mice by inducing initiation and promoting degradation process of autophagy.
m(6) A Reader YTHDF1-Targeting Engineered Small Extracellular Vesicles for Gastric Cancer Therapy via Epigenetic and Immune Regulation.
Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.
Ferroptotic stress facilitates smooth muscle cell dedifferentiation in arterial remodelling by disrupting mitochondrial homeostasis.
ARID2 mitigates hepatic steatosis via promoting the ubiquitination of JAK2.
Protein engineering reveals that gasdermin A preferentially targets mitochondrial membranes over the plasma membrane during pyroptosis.
Disruption of the interaction between mutationally activated Gα(q) and Gβγ attenuates aberrant signaling.
Mitochondria-localized lncRNA HITT inhibits fusion by attenuating formation of mitofusin-2 homotypic or heterotypic complexes.
Antidepression of Xingpijieyu formula targets gut microbiota derived from depressive disorder.
Loss of TDP-43 function underlies hippocampal and cortical synaptic deficits in TDP-43 proteinopathies.
NRP1 contributes to stemness and potentiates radioresistance via WTAP-mediated m6A methylation of Bcl-2 mRNA in breast cancer.
Ubiquitin D promotes the progression of rheumatoid arthritis via activation of the p38 MAPK pathway.
An angiogenesis‑related lncRNA signature for the prognostic prediction of patients with bladder cancer and LINC02321 promotes bladder cancer progression via the VEGFA signaling pathway.
Aging-accelerated differential production and aggregation of STAT3 protein in neuronal cells and neural stem cells in the male mouse spinal cord.
Hypoxia-responsive covalent organic framework by single NIR laser-triggered for multimodal synergistic therapy of triple-negative breast cancer.
Hyaluronic acid mediated Fe(3)O(4) nanocubes reversing the EMT through targeted cancer stem cell.
Exploration the role of INHBA in Hu sheep granulosa cells using RNA-Seq.
Protective effect of human umbilical cord mesenchymal stem cell derived conditioned medium in a mutant TDP-43 induced motoneuron-like cellular model of ALS.
PBX1-SIRT1 Positive Feedback Loop Attenuates ROS-Mediated HF-MSC Senescence and Apoptosis.
Id4 modulates salivary gland homeostasis and its expression is downregulated in IgG4-related disease via miR-486-5p.
Smart nanostructures for targeted oxygen-producing photodynamic therapy of skin photoaging and potential mechanism.
Barrier-penetrating liposome targeted delivery of basic fibroblast growth factor for spinal cord injury repair.
Melatonin alleviates BDE-209-induced cognitive impairment and hippocampal neuroinflammation by modulating microglia polarization via SIRT1-mediated HMGB1/TLR4/NF-κB pathway.
GDF15 negatively regulates chemosensitivity via TGFBR2-AKT pathway-dependent metabolism in esophageal squamous cell carcinoma.
SPON2 promotes the bone metastasis of lung adenocarcinoma via activation of the NF-κB signaling pathway.
Decreased expression and DNA hypermethylation of syncytin-1 in human villus tissues with unexplained recurrent spontaneous abortion.
Capsaicin alleviates cisplatin-induced muscle loss and atrophy in vitro and in vivo.
Chemical constituents from the stems and leaves of Amomum villosum Lour. and their anti-inflammatory and antioxidant activities.
Honokiol alleviated neurodegeneration by reducing oxidative stress and improving mitochondrial function in mutant SOD1 cellular and mouse models of amyotrophic lateral sclerosis.
Vaspin accelerates the proliferation, invasion and metastasis of Triple-Negative breast cancer through MiR-33a-5p/ABHD2.
ITGA5 and ITGB1 contribute to Sorafenib resistance by promoting vasculogenic mimicry formation in hepatocellular carcinoma.
WWOX activates autophagy to alleviate lipopolysaccharide-induced acute lung injury by regulating mTOR.
Matrix metalloproteinase-21 promotes metastasis via increasing the recruitment and M2 polarization of macrophages in HCC.
α-Synuclein induces Th17 differentiation and impairs the function and stability of Tregs by promoting RORC transcription in Parkinson's disease.
Omega-3 polyunsaturated fatty acids inhibit cardiomyocyte apoptosis and attenuate sepsis-induced cardiomyopathy.
Functional and miRNA regulatory characteristics of INSIG genes highlight the key role of lipid synthesis in the liver of chicken (Gallus gallus).
Manipulation of PD-L1 Endosomal Trafficking Promotes Anticancer Immunity.
Loss-of-Function of p21-Activated Kinase 2 Links BMP Signaling to Neural Tube Patterning Defects.
Non-Lethal Concentrations of CdCl(2) Cause Marked Alternations in Cellular Stress Responses within Exposed Sertoli Cell Line.
Neddylation of EphB1 Regulates Its Activity and Associates with Liver Fibrosis.
Double Blast Wave Primary Effect on Synaptic, Glymphatic, Myelin, Neuronal and Neurovascular Markers.
RRP15 deficiency induces ribosome stress to inhibit colorectal cancer proliferation and metastasis via LZTS2-mediated β-catenin suppression.
Effect of CUX1 on the Proliferation of Hu Sheep Dermal Papilla Cells and on the Wnt/β-Catenin Signaling Pathway.
Microglia participate in postoperative cognitive dysfunction by mediating the loss of inhibitory synapse through the complement pathway.
α-Tubulin detyrosination links the suppression of MCAK activity with taxol cytotoxicity.
Daphnetin Improves Neuropathic Pain by Inhibiting the Expression of Chemokines and Inflammatory Factors in the Spinal Cord and Interfering with Glial Cell Polarization.
Single-cell transcriptome analysis identifies Versican(+) myofibroblast as a hallmark for thoracic aortic aneurysm marked by activation of PI3K-AKT signaling pathway.
Epigenetic Regulation of miR-25 and Lnc107153 on Expression of Seasonal Estrus Key Gene CHGA in Sheep.
Isorhamnetin protects porcine oocytes from zearalenone-induced reproductive toxicity through the PI3K/Akt signaling pathway.
Upregulated GPRC5A disrupting the Hippo pathway promotes the proliferation and migration of pancreatic cancer cells via the cAMP-CREB axis.
Increased expression of glucagon-like peptide-1 and cystic fibrosis transmembrane conductance regulator in the ileum and colon in mouse treated with metformin.
The pseudogene DUXAP10 contributes to gefitinib resistance in NSCLC by repressing OAS2 expression.
Cofilin promotes tau pathology in Alzheimer's disease.
Negative regulation of TREM2-mediated C9orf72 poly-GA clearance by the NLRP3 inflammasome.
Synergistic Effect of Hydrogen and 5-Aza on Myogenic Differentiation through the p38 MAPK Signaling Pathway in Adipose-Derived Mesenchymal Stem Cells.
Mesenchymal Stem Cells Ameliorate Fibrosis by Enhancing Autophagy via Inhibiting Galectin-3/Akt/mTOR Pathway and by Alleviating the EMT via Inhibiting Galectin-3/Akt/GSK3β/Snail Pathway in NRK-52E Fibrosis.
Supplementation with α-ketoglutarate improved the efficacy of anti-PD1 melanoma treatment through epigenetic modulation of PD-L1.
Knockdown of MEF2D inhibits the development and progression of B-cell acute lymphoblastic leukemia.
The upregulation of peripheral blood polyamine metabolites spermidine and spermine in children with hand, foot, mouth disease is related to enterovirus 71 capsid protein VP1, but not VP4.
Rab8a as a mitochondrial receptor for lipid droplets in skeletal muscle.
Cdh5-mediated Fpn1 deletion exerts neuroprotective effects during the acute phase and inhibitory effects during the recovery phase of ischemic stroke.
Cell-type-specific regulation of APOE levels in human neurons by the Alzheimer's disease risk gene SORL1.
TNF-α contributes to sarcopenia through caspase-8/caspase-3/GSDME-mediated pyroptosis.
Stimulation of Hepatic Ferritinophagy Mitigates Irp2 Depletion-Induced Anemia.
Protective Potential of β-Hydroxybutyrate against Glucose-Deprivation-Induced Neurotoxicity Involving the Modulation of Autophagic Flux and the Monomeric Aβ Level in Neuro-2a Cells.
RhoGDIα regulates spermatogenesis through Rac1/cofilin/F-actin signaling.
Comparison of human PEX knockout cell lines suggests a dual role of PEX1 in peroxisome biogenesis.
Comprehensive landscape of immune-based classifier related to early diagnosis and macrophage M1 in spinal cord injury.
THADA inhibition in mice protects against type 2 diabetes mellitus by improving pancreatic β-cell function and preserving β-cell mass.
PAK2 is essential for chromosome alignment in metaphase I oocytes.
Skeletal dysplasia-causing TRPV4 mutations suppress the hypertrophic differentiation of human iPSC-derived chondrocytes.
Single-cell transcriptomic dissection of the cellular and molecular events underlying the triclosan-induced liver fibrosis in mice.
METTL14-dependent maturation of pri-miR-17 regulates mitochondrial homeostasis and induces chemoresistance in colorectal cancer.
Mutation in Smek2 regulating hepatic glucose metabolism causes hypersarcosinemia and hyperhomocysteinemia in rats.
Infralimbic YTHDF1 is necessary for the beneficial effects of acute mild exercise on auditory fear extinction retention.
Pro-fibrotic and apoptotic activities of circARAP1 in myocardial ischemia-reperfusion injury.
BMAL1/p53 mediating bronchial epithelial cell autophagy contributes to PM2.5-aggravated asthma.
Iron overload modulates follicular microenvironment via ROS/HIF-1α/FSHR signaling.
Serine hydroxymethyltransferase 2 knockdown induces apoptosis in ccRCC by causing lysosomal membrane permeabilization via metabolic reprogramming.
TIM-4 orchestrates mitochondrial homeostasis to promote lung cancer progression via ANXA2/PI3K/AKT/OPA1 axis.
Rumen-protected glucose stimulates the secretion of reproductive hormones and the mTOR/AKT signaling pathway in the ovaries of early postpartum.
L-Ascorbic Acid 2-Phosphate Attenuates Methylmercury-Induced Apoptosis by Inhibiting Reactive Oxygen Species Accumulation and DNA Damage in Human SH-SY5Y Cells.
Ferroptosis Inducers Kill Mesenchymal Stem Cells Affected by Neuroblastoma.
B-lymphoid tyrosine kinase-mediated FAM83A phosphorylation elevates pancreatic tumorigenesis through interacting with β-catenin.
High glucose-induced glucagon resistance and membrane distribution of GCGR revealed by super-resolution imaging.
Mulberroside A alleviates osteoarthritis via restoring impaired autophagy and suppressing MAPK/NF-κB/PI3K-AKT-mTOR signaling pathways.
WWP2 drives the progression of gastric cancer by facilitating the ubiquitination and degradation of LATS1 protein.
Chemical Proteomics with Novel Fully Functionalized Fragments and Stringent Target Prioritization Identifies the Glutathione-Dependent Isomerase GSTZ1 as a Lung Cancer Target.
Amino acid substitutions in norovirus VP1 dictate cell tropism via an attachment process dependent on membrane mobility.
N(6)-methyladenosine modification in 18S rRNA promotes tumorigenesis and chemoresistance via HSF4b/HSP90B1/mutant p53 axis.
The Alpha-1 Subunit of the Na(+)/K(+)-ATPase (ATP1A1) Is a Host Factor Involved in the Attachment of Porcine Epidemic Diarrhea Virus.
ERRα Up-Regulates Invadopodia Formation by Targeting HMGCS1 to Promote Endometrial Cancer Invasion and Metastasis.
Transplantation of A2 type astrocytes promotes neural repair and remyelination after spinal cord injury.
A bat MERS-like coronavirus circulates in pangolins and utilizes human DPP4 and host proteases for cell entry.
Early activation of Toll-like receptor-3 reduces the pathological progression of Alzheimer's disease in APP/PS1 mouse.
The Degree of Hydrolysis and Peptide Profile Affect the Anti-Fatigue Activities of Whey Protein Hydrolysates in Promoting Energy Metabolism in Exercise Mice.
Six first-line tyrosine kinase inhibitors reveal novel inhibition potential for the EGFR S768I mutation.
Exendin-4 alleviates myocardial ischemia reperfusion injury by enhancing autophagy through promoting nuclear translocation of TFEB.
Exosomal circTUBGCP4 promotes vascular endothelial cell tipping and colorectal cancer metastasis by activating Akt signaling pathway.
The m(6)A methyltransferase METTL3 affects cell proliferation and migration by regulating YAP expression in Hirschsprung disease.
Ferroptosis participated in hippocampal neuroinflammation damage of in offspring rats after maternal sleep deprivation.
Selenium alleviates cadmium-induced mitophagy through FUNDC1-mediated mitochondrial quality control pathway in the lungs of sheep.
Design, synthesis and anti-AD effects of dual inhibitor targeting glutaminyl cyclase/GSK-3β.
Sulforaphane attenuates microglia-mediated neuronal damage by down-regulating the ROS/autophagy/NLRP3 signal axis in fibrillar Aβ-activated microglia.
Centriolar satellites expedite mother centriole remodeling to promote ciliogenesis.
The oncogenic and immunological roles of histidine triad nucleotide-binding protein 1 in human cancers and their experimental validation in the MCF-7 cell line.
BRD7 inhibits enhancer activity and expression of BIRC2 to suppress tumor growth and metastasis in nasopharyngeal carcinoma.
A genome-wide CRISPR-Cas9 knockout screen identifies FSP1 as the warfarin-resistant vitamin K reductase.
Discrepant Activation Pattern of Inflammation and Pyroptosis Induced in Dermal Fibroblasts in Response to Dengue Virus Serotypes 1 and 2 and Nonstructural Protein 1.
Intersection of immune and oncometabolic pathways drives cancer hyperprogression during immunotherapy.
Gelatin methacryloyl (GelMA) loaded with concentrated hypoxic pretreated adipose-derived mesenchymal stem cells(ADSCs) conditioned medium promotes wound healing and vascular regeneration in aged skin.
Mst1 attenuates myocardial ischemia/reperfusion injury following heterotopic heart transplantation in mice through regulating Keap1/Nrf2 axis.
Repositioning Lomitapide to block ZDHHC5-dependant palmitoylation on SSTR5 leads to anti-proliferation effect in preclinical pancreatic cancer models.
A Novel Prenylflavonoid Icariside I Ameliorates Estrogen Deficiency-Induced Osteoporosis via Simultaneous Regulation of Osteoblast and Osteoclast Differentiation.
Qian Yang Yu Yin granule improves hypertensive renal damage: A potential role for TRPC6-CaMKKβ-AMPK-mTOR-mediated autophagy.
Network pharmacology analysis combined with experimental validation to explore the therapeutic mechanism of Schisandra Chinensis Mixture on diabetic nephropathy.
KNTC1, regulated by HPV E7, inhibits cervical carcinogenesis partially through Smad2.
Downregulation of CYRI-B promotes migration, invasion and EMT by activating the Rac1-STAT3 pathway in gastric cancer.
RPS14 promotes the development and progression of glioma via p53 signaling pathway.
Succinate-SUCNR1 induces renal tubular cell apoptosis.
The collateral activity of RfxCas13d can induce lethality in a RfxCas13d knock-in mouse model.
Exosomal RBP4 potentiated hepatic lipid accumulation and inflammation in high-fat-diet-fed mice by promoting M1 polarization of Kupffer cells.
Aerobic Exercise Ameliorates Myocardial Fibrosis via Affecting Vitamin D Receptor and Transforming Growth Factor-β1 Signaling in Vitamin D-Deficient Mice.
The miR-100-5p Targets SMARCA5 to Regulate the Apoptosis and Intracellular Survival of BCG in Infected THP-1 Cells.
SLAMF7/STAT6 Pathway Inhibits Innate Immune Response in Late-Stage Human Acanthamoeba Keratitis: A Comparative Transcriptome Analysis.
HSPB8 facilitates prostate cancer progression via activating the JAK/STAT3 signaling pathway.
Inhibition of Pard3 promotes breast cancer metastasis via the USP28 mediated deubiquitination of Snail1.
Exosomes derived from human umbilical cord mesenchymal stem cells loaded with RVG-Lamp2b and Netrin-1 promotes Schwann cell invasion and migration.
Estrogen inhibits the differentiation of fibroblasts induced by high stiffness matrix by enhancing DNMT1 expression.
AKAP12 inhibits esophageal squamous carcinoma cell proliferation, migration, and cell cycle via the PI3K/AKT signaling pathway.
Survivin as a mediator of stiffness-induced cell cycle progression and proliferation of vascular smooth muscle cells.
HDAC3 aberration-incurred GPX4 suppression drives renal ferroptosis and AKI-CKD progression.
High Plant Protein Diet Ameliorated Hepatic Lipid Accumulation Through the Modulation of Gut Microbiota.
miR-139-3p/Wnt5A Axis Inhibits Metastasis in Hepatoblastoma.
CUDC‑101 is a potential target inhibitor for the EGFR‑overexpression bladder cancer cells.
JSI-124 inhibits cell proliferation and tumor growth by inducing autophagy and apoptosis in murine malignant mesothelioma.
Qiqilian ameliorates vascular endothelial dysfunction by inhibiting NLRP3-ASC inflammasome activation in vivo and in vitro.
Protective effect of Qingluotongbi formula against Tripterygium wilfordii induced liver injury in mice by improving fatty acid β-oxidation and mitochondrial biosynthesis.
Da-Yuan-Yin decoction polyphenol fraction attenuates acute lung injury induced by lipopolysaccharide.
Mechanisms of dihydromyricetin against hepatocellular carcinoma elucidated by network pharmacology combined with experimental validation.
Schwann Cell-Derived Exosomes Ameliorate Paclitaxel-Induced Peripheral Neuropathy Through the miR-21-Mediated PTEN Signaling Pathway.
Cuproptosis-related molecular patterns and gene (ATP7A) in hepatocellular carcinoma and their relationships with tumor immune microenvironment and clinical features.
Glioblastoma cellular MAP4K1 facilitates tumor growth and disrupts T effector cell infiltration.
TUBA1A licenses APC/C-mediated mitotic progression to drive glioblastoma growth by inhibiting PLK3.
Exosomal microRNA-223 from neutrophil-like cells inhibits osteogenic differentiation of PDLSCs through the cGMP-PKG signaling pathway.
DMPP attenuates lipopolysaccharide-induced lung injury by inhibiting glycocalyx degradation through activation of the cholinergic anti-inflammatory pathway.
Noncoding mutations cause super-enhancer retargeting resulting in protein synthesis dysregulation during B cell lymphoma progression.
Single-cell analysis reveals lysyl oxidase (Lox)(+) fibroblast subset involved in cardiac fibrosis of diabetic mice.
Quercetin alleviates lipopolysaccharide‑induced acute lung injury by inhibiting ferroptosis via the Sirt1/Nrf2/Gpx4 pathway.
An adverse outcome pathway-based approach to assess the neurotoxicity by combined exposure to current-use pesticides.
Bisphenol A induced neuronal apoptosis and enhanced autophagy in vitro through Nrf2/HO-1 and Akt/mTOR pathways.
Licochalcone A induces cell cycle arrest and apoptosis via suppressing MAPK signaling pathway and the expression of FBXO5 in lung squamous cell cancer.
Metformin Improves Comorbid Depressive Symptoms in Mice with Allergic Rhinitis by Reducing Olfactory Bulb Damage.
Transcriptome sequencing identifies prognostic genes involved in gastric adenocarcinoma.
Triggering pyroptosis enhances the antitumor efficacy of PARP inhibitors in prostate cancer.
CircGLIS3 inhibits thyroid cancer invasion and metastasis through miR-146b-3p/AIF1L axis.
CircTLK1 alleviates oxygen-glucose deprivation/reperfusion induced apoptosis in HK-2 cells through miR-136-5p/Bcl2 signal axis.
PFKFB3 downregulation aggravates Angiotensin II-induced podocyte detachment.
Salt-induced phosphoproteomic changes in the subfornical organ in rats with chronic kidney disease.
HBx-induced PLA(2)R overexpression mediates podocyte pyroptosis through the ROS-NLRP3 signaling pathway.
Blockage of EGFR/AKT and mevalonate pathways synergize the antitumor effect of temozolomide by reprogramming energy metabolism in glioblastoma.
Dual network analysis of transcriptome data for discovery of new therapeutic targets in non-small cell lung cancer.
ATR-dependent ubiquitin-specific protease 20 phosphorylation confers oxaliplatin and ferroptosis resistance.
GALNT2, an O-glycosylating enzyme, is a critical regulator of radioresistance of non-small cell lung cancer: evidence from an integrated multi-omics analysis.
Hyperhomocysteinemia lowers serum testosterone concentration via impairing testosterone production in Leydig cells.
Mutation of aspartic acid 262 on estrogen receptor abrogates estradiol signaling pathway.
Classical swine fever virus NS5A protein antagonizes innate immune response by inhibiting the NF-κB signaling.
Higher matrix stiffness promotes VSMC senescence by affecting mitochondria-ER contact sites and mitochondria/ER dysfunction.
Downregulation of ALKBH5 rejuvenates aged human mesenchymal stem cells and enhances their therapeutic efficacy in myocardial infarction.
The SARS-CoV-2 nucleocapsid protein suppresses innate immunity by remodeling stress granules to atypical foci.
Neurovascular dysfunction associated with erectile dysfunction persists after long-term recovery from simulations of weightlessness and deep space irradiation.
β-arrestin1 is an E3 ubiquitin ligase adaptor for substrate linear polyubiquitination.
Multiple N-linked glycosylation sites critically modulate the synaptic abundance of neuroligin isoforms.
Tumor Necrosis Factor Alpha Preconditioned Umbilical Cord Mesenchymal Stem Cell-Derived Extracellular Vesicles Enhance the Inhibition of Necroptosis of Acinar cells in Severe Acute Pancreatitis.
CDC20 promotes radioresistance of prostate cancer by activating Twist1 expression.
An immunogenic cell death-related signature predicts prognosis and immunotherapy response in stomach adenocarcinoma.
Bioinformatic analysis of the expression profile and identification of RhoGDI2 as a biomarker in imatinib-resistant K562 cells.
Polydatin alleviates bleomycin-induced pulmonary fibrosis and alters the gut microbiota in a mouse model.
Xanthohumol attenuates renal ischemia/reperfusion injury by inhibiting ferroptosis.
SPINT2 is involved in the proliferation, migration and phenotypic switching of aortic smooth muscle cells: Implications for the pathogenesis of thoracic aortic dissection.
EIF2α/ATF4 pathway enhances proliferation of mesangial cell via cyclin D1 during endoplasmic reticulum stress in IgA nephropathy.
SIRT6 Knockdown in Buffalo Fetal Fibroblasts Exacerbates Premature Senescence Caused by DNA and Telomere Damage.
Ferritinophagy-mediated apoptosis and paraptosis induction involved MAPK and PI3K/AKT pathway in mechanism of an iron chelator.
USP10 promotes the progression of triple-negative breast cancer by enhancing the stability of TCF4 protein.
SINE-VNTR-Alu retrotransposon insertion as a novel mutational event underlying Glanzmann thrombasthenia.
Monopolar spindle 1 contributes to tamoxifen resistance in breast cancer through phosphorylation of estrogen receptor α.
Vitamin D/Vitamin D receptor mitigates cisplatin-induced acute kidney injury by down-regulating C5aR.
Dexmedetomidine attenuates the neuroinflammation and cognitive dysfunction in aged mice by targeting the SNHG14/miR‑340/NF‑κB axis.
NSUN2-mediated m5C modification of HBV RNA positively regulates HBV replication.
Overexpression of LOX-1 in hepatocytes protects vascular smooth muscle cells from phenotype transformation and wire injury induced carotid neoatherosclerosis through ALOX15.
Glimepiride, a novel soluble epoxide hydrolase inhibitor, protects against heart failure via increasing epoxyeicosatrienoic acids.
Dietary pectin attenuates Salmonella typhimurium-induced colitis by modulating the TLR2-NF-κB pathway and intestinal microbiota in mice.
Sanguinarine induces apoptosis in osteosarcoma by attenuating the binding of STAT3 to the single-stranded DNA-binding protein 1 (SSBP1) promoter region.
5-HT4 Receptor is Protective for MPTP-induced Parkinson's Disease Mice Via Altering Gastrointestinal Motility or Gut Microbiota.
TRAF5 regulates intestinal mucosal Th1/Th17 cell immune responses via Runx1 in colitis mice.
The synthetic oleanane triterpenoid CDDO-2P-Im binds GRP78/BiP to induce unfolded protein response-mediated apoptosis in myeloma.
Knockdown of LMNA inhibits Akt/β-catenin-mediated cell invasion and migration in clear cell renal cell carcinoma cells.
Salvianolic acid A alleviates heart failure with preserved ejection fraction via regulating TLR/Myd88/TRAF/NF-κB and p38MAPK/CREB signaling pathways.
Liensinine alleviates LPS-induced acute lung injury by blocking autophagic flux via PI3K/AKT/mTOR signaling pathway.
Traditional Medicine Pien Tze Huang Suppresses Colorectal Tumorigenesis Through Restoring Gut Microbiota and Metabolites.
METTL3-mediated m6A modification of circRNF220 modulates miR-330-5p/survivin axis to promote osteosarcoma progression.
Identification of glycogene-based prognostic signature and validation of B3GNT7 as a potential biomarker and therapeutic target in breast cancer.
B7-H3 and CD47 co-expression in gastric cancer is a predictor of poor prognosis and potential targets for future dual-targeting immunotherapy.
Discovery of selective and potent USP22 inhibitors via structure-based virtual screening and bioassays exerting anti-tumor activity.
Circadian Clock REV-ERBs Agonist SR9009 Induces Synergistic Antitumor Activity in Multiple Myeloma by Suppressing Glucose-Regulated Protein 78-Dependent Autophagy and Lipogenesis.
Stimulator of interferon genes promotes diabetic sarcopenia by targeting peroxisome proliferator activated receptors γ degradation and inhibiting fatty acid oxidation.
CiRS-7 Enhances the Liquid-liquid Phase Separation of miRISC and Promotes DNA Damage Repair.
The pseudokinase MLKL contributes to host defense against Streptococcus pluranimalium infection by mediating NLRP3 inflammasome activation and extracellular trap formation.
Cyclin-dependent kinase 5 negatively regulates antiviral immune response by disrupting myeloid differentiation primary response protein 88 self-association.
Effects of different types of neonatal pain on somatosensory and cognitive development in male juvenile rats.
L-F001, a multifunctional fasudil-lipoic acid dimer, antagonizes hypoxic-ischemic brain damage by inhibiting the TLR4/MyD88 signaling pathway.
Zinc regulates a specific subpopulation of VEGFA + microglia to improve the hypoxic microenvironment for functional recovery after spinal cord injury.
Decreased SIRT1 mRNA expression in peripheral blood mononuclear cells from patients with neuromyelitis optica spectrum disorders.
Ginsenoside Rb1 protects hippocampal neurons in depressed rats based on mitophagy-regulated astrocytic pyroptosis.
NSUN2-mediated M(5)c methylation of IRF3 mRNA negatively regulates type I interferon responses during various viral infections.
DUSP2 affects bladder cancer prognosis by down-regulating MEK/ERK and P38 MAPK signaling pathways through PTPN7.
ZNF746 promotes M2 macrophage polarisation and favours tumour progression in breast cancer via the Jagged1/Notch pathway.
Umbelliferone attenuates cisplatin-induced acute kidney injury by inhibiting oxidative stress and inflammation via NRF2.
STAG2 Regulates Homologous Recombination Repair and Sensitivity to ATM Inhibition.
Targeting CBX3 with a Dual BET/PLK1 Inhibitor Enhances the Antitumor Efficacy of CDK4/6 Inhibitors in Prostate Cancer.
SUCLG2 Regulates Mitochondrial Dysfunction through Succinylation in Lung Adenocarcinoma.
NS2B-D55E and NS2B-E65D Variations are Responsible for Differences in NS2B-NS3 Protease Activities Between Japanese Encephalitis Virus Genotype I and III in Fluorogenic Peptide Model.
Heat shock protein HSPA13 promotes hepatocellular carcinoma progression by stabilizing TANK.
Nutrient deprivation alters the rate of COPII subunit recruitment at ER subdomains to tune secretory protein transport.
Structural and biochemical insights into the interaction mechanism underlying HORMAD1 and its partner proteins.
VEGFA mRNA-LNP promotes biliary epithelial cell-to-hepatocyte conversion in acute and chronic liver diseases and reverses steatosis and fibrosis.
The hypothalamic steroidogenic pathway mediates susceptibility to inflammation-evoked depression in female mice.
IFITM1 and IFITM3 Proteins Inhibit the Infectivity of Progeny HIV-1 without Disrupting Envelope Glycoprotein Clusters.
Aldehyde dehydrogenase 2-mediated aldehyde metabolism promotes tumor immune evasion by regulating the NOD/VISTA axis.
Spinal-Specific Super Enhancer in Neuropathic Pain.
Androgen signaling stabilizes genomes to counteract senescence by promoting XRCC4 transcription.
GDF15 is a major determinant of ketogenic diet-induced weight loss.
A missense mutant of ocrl1 promotes apoptosis of tubular epithelial cells and disrupts endocytosis and the cell cycle of podocytes in Dent-2 Disease.
RNA-binding motif protein 10 inactivates c-Myc by partnering with ribosomal proteins uL18 and uL5.
Protective Effect of Ginsenoside CK against Autoimmune Hepatitis Induced by Concanavalin A.
Satellite glial GPR37L1 regulates maresin and potassium channel signaling for pain control.
Interplay between stochastic enzyme activity and microtubule stability drives detyrosination enrichment on microtubule subsets.
hsa_circ_0007919 induces LIG1 transcription by binding to FOXA1/TET1 to enhance the DNA damage response and promote gemcitabine resistance in pancreatic ductal adenocarcinoma.
A ketogenic diet reduces age-induced chronic neuroinflammation in mice Running title: ketogenic diet and brain inflammaging.
Establishment of a Fah-LSL mouse model to study BEC-to-hepatocyte conversion.
A20 ameliorates Aspergillus fumigatus keratitis by promoting autophagy and inhibiting NF-κB signaling.
Exopolysaccharide from Weissella confusa J4-1 inhibits colorectal cancer via induction of cell cycle arrest.
DnaJs are enriched in tau regulators.
LncHLEF promotes hepatic lipid synthesis through miR-2188-3p/GATA6 axis and encoding peptides and enhances intramuscular fat deposition via exosome.
Cataract-causing mutations S78F and S78P of γD-crystallin decrease protein conformational stability and drive aggregation.
miRNA-660-3p inhibits malignancy in glioblastoma via negative regulation of APOC1-TGFβ2 signaling pathway.
Function of m(5)C RNA methyltransferase NOP2 in high-grade serous ovarian cancer.
Dexmedetomidine alleviates ferroptosis following hepatic ischemia-reperfusion injury by upregulating Nrf2/GPx4-dependent antioxidant responses.
Preclinical evaluation of RQ3013, a broad-spectrum mRNA vaccine against SARS-CoV-2 variants.
Matrine Targets BTF3 to Inhibit the Growth of Canine Mammary Tumor Cells.
MicroRNA miR-212-5p Regulates the MEK/ERK Signaling Pathway by Targeting A-Raf proto-oncogene serine/threonine-protein kinase (ARAF) to Regulate Cowshed PM(2.5)-Induced NR8383 Apoptosis.
Muscone inhibits angiotensin II-induced cardiac hypertrophy through the STAT3, MAPK and TGF-β/SMAD signaling pathways.
Canthaxanthin Attenuates the Vascular Aging or Endothelial Cell Senescence by Inhibiting Inflammation and Oxidative Stress in Mice.
Jian-Pi-Yi-Shen formula alleviates renal fibrosis by restoring NAD+ biosynthesis in vivo and in vitro.
Inhibition of TGF-β1-induced epithelial-mesenchymal transition in gliomas by DMC-HA.
GDF-15 Inhibits ADP-Induced Human Platelet Aggregation through the GFRAL/RET Signaling Complex.
PDGFRα/β heterodimer activation negatively affects downstream ERK1/2 signaling and cellular proliferation.
NLRP14 deficiency causes female infertility with oocyte maturation defects and early embryonic arrest by impairing cytoplasmic UHRF1 abundance.
Cell-cell and cell-matrix adhesion regulated by Piezo1 is critical for stiffness-dependent DRG neuron aggregation.
E3 ligase Trim35 inhibits LSD1 demethylase activity through K63-linked ubiquitination and enhances anti-tumor immunity in NSCLC.
COPI Vesicle Disruption Inhibits Mineralization via mTORC1-Mediated Autophagy.
Selenium enhances photodynamic therapy of C-phycocyanin against lung cancer via dual regulation of cytotoxicity and antioxidant activity.
A Novel COCH p.D544Vfs*3 Variant Associated with DFNA9 Sensorineural Hearing Loss Causes Pathological Multimeric Cochlin Formation.
GM-CSF improves endometrial receptivity in a thin endometrium rat model by upregulating HOXA10.
The Role of DNMT1 and C/EBPα in the Regulation of CYP11A1 Expression During Syncytialization of Human Placental Trophoblasts.
MNX1 Promotes Anti-HER2 Therapy Sensitivity via Transcriptional Regulation of CD-M6PR in HER2-Positive Breast Cancer.
Amino acid substitutions in norovirus VP1 dictate host dissemination via variations in cellular attachment.
The role of lysosomes as intermediates in betacoronavirus PHEV egress from nerve cells.
Hsa_circ_0007321 regulates Zika virus replication through miR-492/NFKBID/NF-κB signaling pathway.
ZDHHC5-mediated NLRP3 palmitoylation promotes NLRP3-NEK7 interaction and inflammasome activation.
m(6)A modification negatively regulates translation by switching mRNA from polysome to P-body via IGF2BP3.
SIRT3 Regulates Levels of Deacetylated SOD2 to Prevent Oxidative Stress and Mitochondrial Dysfunction During Oocyte Maturation in Pigs.
Schistosome egg-derived extracellular vesicles deliver Sja-miR-71a inhibits host macrophage and neutrophil extracellular traps via targeting Sema4D.
m(6)A methylation-mediated PGC-1α contributes to ferroptosis via regulating GSTK1 in arsenic-induced hepatic insulin resistance.
EphB6 deficiency in intestinal neurons promotes tumor growth in colorectal cancer by neurotransmitter GABA signaling.
Metabolites-Based Network Pharmacology to Preliminarily Verify In Vitro Anti-Inflammatory Effect of Ardisiacrispin B.
Circular RNA circEYA3 promotes the radiation resistance of hepatocellular carcinoma via the IGF2BP2/DTX3L axis.
ESRP1-driven alternative splicing of CLSTN1 inhibits the metastasis of gastric cancer.
Engineering irradiated tumor-derived microparticles as personalized vaccines to enhance anti-tumor immunity.
Regulation of the WNT-CTNNB1 signaling pathway by severe fever with thrombocytopenia syndrome virus in a cap-snatching manner.
Lentiviral mediated delivery of CRISPR/Cas9 reduces intraocular pressure in a mouse model of myocilin glaucoma.
A novel de novo CLTC variant altering RNA splicing causes fetal developmental abnormalities.
Amyloid precursor protein induces reactive astrogliosis.
Dapoxetine, a Selective Serotonin Reuptake Inhibitor, Suppresses Zika Virus Infection In Vitro.
Dexmedetomidine alleviates renal tubular ferroptosis in sepsis-associated AKI by KEAP1 regulating the degradation of GPX4.
Glycyrrhetinic acid attenuates endoplasmic reticulum stress-induced hepatocyte apoptosis via CHOP/DR5/Caspase 8 pathway in cholestasis.
Repositioning of Montelukast to inhibit proliferation of mutated KRAS pancreatic cancer through a novel mechanism that interfere the binding between KRAS and GTP/GDP.
NAMPT mediates PDGF-induced pulmonary arterial smooth muscle cell proliferation by TLR4/NF-κB/PLK4 signaling pathway.
Targeted clearance of mitochondria by an autophagy-tethering compound (ATTEC) and its potential therapeutic effects.
Anti-inflammatory effect of two novel peptides derived from Binglangjiang buffalo whey protein in lipopolysaccharide-stimulated RAW264.7 macrophages.
Mechanism of Huaiqihuang in treatment of diabetic kidney disease based on network pharmacology, molecular docking and in vitro experiment.
Discovery of a Dual Tubulin and Neuropilin-1 (NRP1) Inhibitor with Potent In Vivo Anti-Tumor Activity via Pharmacophore-based Docking Screening, Structure Optimization, and Biological Evaluation.
Discovery of Pyrazolo[1,5-a]pyrimidine Derivative as a Novel and Selective ALKBH5 Inhibitor for the Treatment of AML.
Aloin Attenuates Oxidative Stress, Inflammation, and CCl(4)-Induced Liver Fibrosis in Mice: Possible Role of TGF-β/Smad Signaling.
Efficacy and mechanism of Shenqi Compound in inhibiting diabetic vascular calcification.
A positive feedback circuit driven by m(6)A-modified circular RNA facilitates colorectal cancer liver metastasis.
Histone demethylase KDM4B accelerates the progression of glioblastoma via the epigenetic regulation of MYC stability.
The development of a hiPSC-based platform to identify tissue-dependencies of IDH1 R132H.
Reduced Proteolipid Protein 2 promotes endoplasmic reticulum stress-related apoptosis and increases drug sensitivity in acute myeloid leukemia.
Alleviation of ischemia-reperfusion induced renal injury by chemically modified SOD2 mRNA delivered via lipid nanoparticles.
Efficacy of exon-skipping therapy for DMD cardiomyopathy with mutations in actin binding domain 1.
Transition of allele-specific DNA hydroxymethylation at regulatory loci is associated with phenotypic variation in monozygotic twins discordant for psychiatric disorders.
Hepatic Stellate Cell- and Liver Microbiome-Specific Delivery System for Dihydrotanshinone I to Ameliorate Liver Fibrosis.
Nuclear cGAS restricts L1 retrotransposition by promoting TRIM41-mediated ORF2p ubiquitination and degradation.
Diversity for endoribonuclease nsp15-mediated regulation of alpha-coronavirus propagation and virulence.
Glaesserella parasuis QseBC two-component system senses epinephrine and regulates capD expression.
Dissecting T-cell heterogeneity in esophageal squamous cell carcinoma reveals the potential role of LAIR2 in antitumor immunity.
The Arabidopsis ubiquitin ligases ATL31 and ATL6 regulate plant response to salt stress in an ABA-independent manner.
Co-exposure to molybdenum and cadmium evokes necroptosis and decreases apoptosis in duck myocardium.
TMEM44-AS1 promotes esophageal squamous cell carcinoma progression by regulating the IGF2BP2-GPX4 axis in modulating ferroptosis.
Fatty Acid Oxidation Mediated by Malonyl-CoA Decarboxylase Represses Renal Cell Carcinoma Progression.
Phosphatidylinositol-specific phospholipase C can decrease Müller cell viability and suppress its phagocytic activity by modulating PI3K/AKT signaling pathway.
TP induces hepatic intolerance to FasL-mediated hepatocyte apoptosis by inhibiting XIAP.
The role of ROS-pyroptosis in PM(2.5) induced air-blood barrier destruction.
Pectolinarigenin attenuates hepatic ischemia/reperfusion injury via activation of the PI3K/AKT/Nrf2 signaling pathway.
Metal transporter SLC39A14/ZIP14 modulates regulation between the gut microbiome and host metabolism.
Covalent Targeting of Glutamate Cysteine Ligase to Inhibit Glutathione Synthesis.
AURKAIP1 actuates tumor progression through stabilizing DDX5 in triple negative breast cancer.
Modeling aging and retinal degeneration with mitochondrial DNA mutation burden.
Air-ventilated normothermic machine perfusion alleviates hepatic injury from DCD rat through CYP1A2.
Metformin promotes cGAS/STING signaling pathway activation by blocking AKT phosphorylation in gastric cancer.
The Expression of ZNF268 and Its Role in The Cisplatin-based Chemoresistance of Breast Cancer.
Guf1 overexpression improves pancreatic β cell functions in type 2 diabetes mellitus rats with Roux-en-Y gastric bypass (RYGB) surgery.
The increased expression of cytokeratin 13 leads to an increase in radiosensitivity of nasopharyngeal carcinoma HNE-3 cells by upregulating ERRFI1.
Promotion of hepatic stellate cell activation and liver fibrosis by microRNA-33a-5p through targeting the Dickkopf-1-mediated wingless-related integration site/beta-catenin pathway.
Huoxue Jiedu Recipe represses mitochondrial fission to alleviate submandibular gland inflammation in Sjögren's syndrome.
Pantethine Ameliorates Recognition Impairment in a Mouse Model of Alzheimer's Disease by Modulating Cholesterol Content and Intestinal Flora Species.
CircRNA Galntl6 sponges miR-335 to ameliorate stress-induced hypertension through upregulating Lig3 in rostral ventrolateral medulla.
NOX2 inhibition stabilizes vulnerable plaques by enhancing macrophage efferocytosis via MertK/PI3K/AKT pathway.
DYRK1A-mediated PLK2 phosphorylation regulates the proliferation and invasion of glioblastoma cells.
Overexpression of SERPINA3 suppresses tumor progression by modulating SPOP/NF‑κB in lung cancer.
PRMT1 inhibition promotes ferroptosis sensitivity via ACSL1 upregulation in acute myeloid leukemia.
Theabrownin of raw and ripened pu-erh tea varies in the alleviation of HFD-induced obesity via the regulation of gut microbiota.
Retinoic Acid Prevents α-Synuclein Preformed Fibrils-Induced Toxicity via Inhibiting STAT1-PARP1 Signaling.
SCNN1B regulates the proliferation, migration, and collagen deposition of human lung fibroblasts.
MiR-590-5p promotes cisplatin resistance via targeting hMSH2 in ovarian cancer.
Effects of honokiol protects against chronic kidney disease via BNIP3/NIX and FUNDC1-mediated mitophagy and AMPK pathways.
Dipeptidase‑2 is a prognostic marker in lung adenocarcinoma that is correlated with its sensitivity to cisplatin.
CD44 Drives M1 Macrophage Polarization in Diabetic Retinopathy.
UBP43 promotes epithelial ovarian carcinogenesis via activation of β-catenin signaling pathway.
PLAU contributes to the development of cholangiocarcinoma via activating NF-κB signaling pathway.
LPS-aggravated Ferroptosis via Disrupting Circadian Rhythm by Bmal1/AKT/p53 in Sepsis-Induced Myocardial Injury.
Glutamine metabolic microenvironment drives M2 macrophage polarization to mediate trastuzumab resistance in HER2-positive gastric cancer.
Uncovering pharmacological mechanisms of Phellinus linteus on focal segmental glomeruloscleosis rats through tandem mass tag-based quantitative proteomic analysis, network pharmacology analysis and experimental validation.
Qizhi Jiangtang capsule activates podocyte autophagy in diabetic kidney disease by inhibiting phosphatidylinositol 3-kinase/protein kinase B/mammalian target of rapamycin pathways.
Phosphorylated PTTG1 switches its subcellular distribution and promotes β-catenin stabilization and subsequent transcription activity.
Degradation of MYC by the mutant p53 reactivator drug, COTI-2 in breast cancer cells.
TRAF6 regulates autophagy and apoptosis of melanoma cells through c-Jun/ATG16L2 signaling pathway.
The histone acetyltransferase Mof regulates Runx2 and Osterix for osteoblast differentiation.
Activation of cDCs and iNKT cells contributes to triptolide-induced hepatotoxicity via STING signaling pathway and endoplasmic reticulum stress.
SIRT6 regulates obesity-induced oxidative stress via ENDOG/SOD2 signaling in the heart.
Exposure to MoS2 nanosheets or bulk activated Kruppel-like factor 4 in 3D Caco-2 spheroids in vitro and mouse intestines in vivo.
Farnesoid X receptor is an important target for the treatment of disorders of bile acid and fatty acid metabolism in mice with nonalcoholic fatty liver disease combined with cholestasis.
Construction of coxsackievirus B5 viruses with luciferase reporters and their applications in vitro and in vivo.
RNF167-mediated ubiquitination of Tollip inhibits TNF-α-triggered NF-κB and MAPK activation.
Role of FBXL5 in redox homeostasis and spindle assembly during oocyte maturation in mice.
Dapagliflozin inhibits the activity of lateral habenula to alleviate diabetes mellitus-induced depressive-like behavior.
USP39-mediated deubiquitination of Cyclin B1 promotes tumor cell proliferation and glioma progression.
Bone marrow mesenchymal stem cell-derived exosomal miR-193b-5p reduces pyroptosis after ischemic stroke by targeting AIM2.
The potential oncogenic effect of tissue-specific expression of JC polyoma T antigen in digestive epithelial cells.
Divergent roles of estrogen receptor subtypes in regulating estrogen-modulated colonic ion transports and epithelial repair.
Deubiquitinase USP9X stabilizes RNA m(6)A demethylase ALKBH5 and promotes acute myeloid leukemia cell survival.
Repair of topoisomerase 1-induced DNA damage by tyrosyl-DNA phosphodiesterase 2 (TDP2) is dependent on its magnesium binding.
The RNA-binding protein ZC3H11A interacts with the nuclear poly(A)-binding protein PABPN1 and alters polyadenylation of viral transcripts.
ZBTB7A regulates primed-to-naïve transition of pluripotent stem cells via recognition of the PNT-associated sequence by zinc fingers 1-2 and recognition of γ-globin -200 gene element by zinc fingers 1-4.
RNA m5C methylation orchestrates BLCA progression via macrophage reprogramming.
The formation of migrasomes is initiated by the assembly of sphingomyelin synthase 2 foci at the leading edge of migrating cells.
Hyperuricemia promotes the progression of atherosclerosis by activating endothelial cell pyroptosis via the ROS/NLRP3 pathway.
Loss of TDP-43 promotes somatic CAG repeat expansion in Huntington's disease knock-in mice.
Trastuzumab potentiates doxorubicin-induced cardiotoxicity via activating the NLRP3 inflammasome in vivo and in vitro.
Anti-inflammatory iridoid glycosides from Paederia scandens (Lour.) Merrill.
Difenoconazole disrupts carp intestinal physical barrier and causes inflammatory response via triggering oxidative stress and apoptosis.
The MGF300-2R protein of African swine fever virus is associated with viral pathogenicity by promoting the autophagic degradation of IKKα and IKKβ through the recruitment of TOLLIP.
Dectin-1 deficiency alleviates diabetic cardiomyopathy by attenuating macrophage-mediated inflammatory response.
The Warburg micro syndrome protein RAB3GAP1 modulates neuronal morphogenesis and interacts with axon elongation end ER-Golgi trafficking factors.
3D artificial sebocyte glands from inertial focusing effect for facile and flexible analysis of light damage and drug screening.
Non-invasive activation of intratumoural gene editing for improved adoptive T-cell therapy in solid tumours.
Exendin-4 and linagliptin attenuate neuroinflammation in a mouse model of Parkinson's disease.
Triclocarban exposure aggravates dextran sulfate sodium-induced colitis by deteriorating the gut barrier function and microbial community in mice.
microRNA-651-5p affects the proliferation, migration, and invasion of lung cancer cells by regulating Calmodulin 2 expression.
PAG neuronal NMDARs activation mediated morphine-induced hyperalgesia by HMGB1-TLR4 dependent microglial inflammation.
Sanghuangporus vaninii ethanol extract alleviates hyperuricemic renal injury by regulating the uric acid transporters and inhibiting HK-2 apoptosis.
Hepatoprotective effect of Typhaneoside on non-alcoholic fatty liver disease via farnesoid X receptor in vivo and in vitro.
The Chinese herbal medicine Fufang Zhenzhu Tiaozhi ameliorates diabetic cardiomyopathy by regulating cardiac abnormal lipid metabolism and mitochondrial dynamics in diabetic mice.
Fluorofenidone protects against acute liver failure in mice by regulating MKK4/JNK pathway.
CACYBP knockdown inhibits progression of prostate cancer via p53.
Split-Cas9-based targeted gene editing and nanobody-mediated proteolysis-targeting chimeras optogenetically coordinated regulation of Survivin to control the fate of cancer cells.
MIF promotes Th17 cell differentiation in Hashimoto's thyroiditis by binding HVEM and activating NF-κB signaling pathway.
Immunosensitivity mediated by downregulated AKT1-SKP2 induces anti-PD-1-associated thyroid immune injury.
ROR1/STAT3 positive feedback loop facilitates cartilage degeneration in Osteoarthritis through activation of NF-κB signaling pathway.
TSLP/TSLPR promotes renal fibrosis by activating STAT3 in renal fibroblasts.
The innate immune sensor STING accelerates neointima formation via NF-κB signaling pathway.
Origin of the OAS-RNase L innate immune pathway before the rise of jawed vertebrates via molecular tinkering.
ROS Scavenging Nanozyme Modulates Immunosuppression for Sensitized Cancer Immunotherapy.
Identification and validation of Birc5 as a novel activated cell cycle program biomarker associated with infiltration of immunosuppressive myeloid-derived suppressor cells in hepatocellular carcinoma.
Screening of novel serum biomarkers for gastric cancer in coastal populations using a protein microarray.
WDR54 exerts oncogenic roles in T-cell acute lymphoblastic leukemia.
TRIM29 acts as a potential senescence suppressor with epigenetic activation in nasopharyngeal carcinoma.
Augmenter of liver regeneration promotes drug resistance of acute lymphoblastic leukemia through the alteration of mitochondrial functions and the inhibition of the mitochondrial apoptosis pathway.
Tumor-secreted GRP78 induces M2 polarization of macrophages by promoting lipid catabolism.
A high-concentrate diet induces mitochondrial dysfunction by activating the MAPK signaling pathway in the mammary gland of dairy cows.
Bone Marrow Mesenchymal Stem Cell-Derived Dermcidin-Containing Migrasomes enhance LC3-Associated Phagocytosis of Pulmonary Macrophages and Protect against Post-Stroke Pneumonia.
Structural Characterization of Zinc-Sucrose Complex and Its Ability to Promote Zinc Absorption in Caco-2 Monolayer Cells and Mice.
Tau deficiency inhibits classically activated macrophage polarization and protects against collagen-induced arthritis in mice.
SMAD2 inhibits pyroptosis of fibroblast-like synoviocytes and secretion of inflammatory factors via the TGF-β pathway in rheumatoid arthritis.
Metformin Ameliorates Postoperative Cognitive Dysfunction through Regulation of the AMPK/SIRT1 Pathway.
The deubiquitinase EIF3H promotes hepatocellular carcinoma progression by stabilizing OGT and inhibiting ferroptosis.
Toxoplasma gondii Reactivation Aggravating Cardiac Function Impairment in Mice.
Systemic Pharmacology Reveals the Potential Targets and Signaling Mechanisms in the Adjuvant Treatment of Brucellosis with Traditional Chinese Medicine.
CircUSP48 promotes malignant behavior by regulating CYR61 via miR-365 in osteosarcoma.
YY1 regulates the proliferation and invasion of triple-negative breast cancer via activating PLAUR.
Identification of a novel bile marker clusterin and a public online prediction platform based on deep learning for cholangiocarcinoma.
Mitochondrial carrier 1 (MTCH1) governs ferroptosis by triggering the FoxO1-GPX4 axis-mediated retrograde signaling in cervical cancer cells.
Intermittent dietary methionine deprivation facilitates tumoral ferroptosis and synergizes with checkpoint blockade.
FERM domain containing kindlin 1 knockdown attenuates inflammation induced by intracerebral hemorrhage in rats via NLR family pyrin domain containing 3/nuclear factor kappa B pathway.
Ultrafast single-molecule imaging reveals focal adhesion nano-architecture and molecular dynamics.
Transcriptional variation in Babesia gibsoni (Wuhan isolate) between in vivo and in vitro cultures in blood stage.
ABCD1 Transporter Deficiency Results in Altered Cholesterol Homeostasis.
Inhibition of Trichinella spiralis Membrane-Associated Progesterone Receptor (MAPR) Results in a Reduction in Worm Burden.
Inhibitory effect of Dendrobium officinale polysaccharide on oxidative damage of glial cells in aging mice by regulating gut microbiota.
ADRM1/RPN13 attenuates cartilage extracellular matrix degradation via enhancing UCH37-mediated ALK5 deubiquitination.
CAR-T cells targeting CD38 and LMP1 exhibit robust antitumour activity against NK/T cell lymphoma.
Hepatocyte-specific Sox9 knockout ameliorates acute liver injury by suppressing SHP signaling and improving mitochondrial function.
Effect of Gut Microbiota on the Pharmacokinetics of Nifedipine in Spontaneously Hypertensive Rats.
Ypel5 regulates liver development and function in zebrafish.
Mis-splicing Drives Loss of Function of p53(E224D) Point Mutation.
Cell-type-specific regulation of APOE and CLU levels in human neurons by the Alzheimer's disease risk gene SORL1.
The miR-17∼92 miRNAs promote plasma cell differentiation by suppressing SOCS3-mediated NIK degradation.
NFYC-37 promotes tumor growth by activating the mevalonate pathway in bladder cancer.
MOF-mediated acetylation of SIRT6 disrupts SIRT6-FOXA2 interaction and represses SIRT6 tumor-suppressive function by upregulating ZEB2 in NSCLC.
Dendritic distribution of autophagosomes underlies pathway-selective induction of LTD.
Sox10 escalates vascular inflammation by mediating vascular smooth muscle cell transdifferentiation and pyroptosis in neointimal hyperplasia.
POGZ suppresses 2C transcriptional program and retrotransposable elements.
A p53/LINC00324 positive feedback loop suppresses tumor growth by counteracting SET-mediated transcriptional repression.
SP1-Induced Upregulation of LncRNA AFAP1-AS1 Promotes Tumor Progression in Triple-Negative Breast Cancer by Regulating mTOR Pathway.
Stem of Sorbus commixta Hedl. Extract Inhibits Cartilage Degradation and Arthritic Pain in Experimental Model via Anti-Inflammatory Activity.
Measuring tryptophan dynamics using fast scan cyclic voltammetry at carbon fiber microelectrodes with improved sensitivity and selectivity.
Riluzole Suppresses Growth and Enhances Response to Endocrine Therapy in ER+ Breast Cancer.
Disulfiram/Copper Induce Ferroptosis in Triple-Negative Breast Cancer Cell Line MDA-MB-231.
Rutaecarpine Ameliorates Murine N-Methyl-N'-Nitro-N-Nitrosoguanidine-Induced Chronic Atrophic Gastritis by Sonic Hedgehog Pathway.
LncRNA GAS5-hnRNPK axis inhibited ovarian cancer progression via inhibition of AKT signaling in ovarian cancer cells.
EZH2 inhibitor Tazemetostat synergizes with JQ-1 in esophageal cancer by inhibiting c-Myc signaling pathway.
SPDEF enhances cancer stem cell-like properties and tumorigenesis through directly promoting GALNT7 transcription in luminal breast cancer.
The DDUP protein encoded by the DNA damage-induced CTBP1-DT lncRNA confers cisplatin resistance in ovarian cancer.
Hyperelatolides A-D, Antineuroinflammatory Constituents with Unusual Carbon Skeletons from Hypericum elatoides.
Structural basis for specific DNA sequence motif recognition by the TFAP2 transcription factors.
Liquiritigenin Confers Liver Protection by Enhancing NRF2 Signaling through Both Canonical and Non-canonical Signaling Pathways.
A20 promotes colorectal cancer immune evasion by upregulating STC1 expression to block "eat-me" signal.
Unraveling Vulnerabilities in Endocrine Therapy-Resistant HER2+/ER+ Breast Cancer.
HtrA1 prevents and reverses α-synuclein aggregation, rendering it non-toxic and seeding incompetent.
GABA(B) Receptor Activation Attenuates Neuronal Pyroptosis in Post-cardiac Arrest Brain Injury.
Oxidative Stress-mediated Sprouty-related Protein with an EVH1 Domain 1 Down-regulation Contributes to Resisting Oxidative Injury in Microglia.
Injectable photocrosslinking spherical hydrogel-encapsulated targeting peptide-modified engineered exosomes for osteoarthritis therapy.
Knockdown of SETD2 promotes erastin-induced ferroptosis in ccRCC.
USP33 promotes nonalcoholic fatty acid disease-associated fibrosis in gerbils via the c-myc signaling.
[Guizhi Fuling Capsule inhibits migration and induces apoptosis of human ovarian cancer cells by regulating the NF-κB signaling pathway].
[Dihydromyricetin alleviates pyroptosis and necroptosis in mice with MPTP-induced chronic Parkinson's disease by inducing autophagy].
B7-H3 confers stemness characteristics to gastric cancer cells by promoting glutathione metabolism through AKT/pAKT/Nrf2 pathway.
UCP1 alleviates renal interstitial fibrosis progression through oxidative stress pathway mediated by SIRT3 protein stability.
Role of dendritic cells in MYD88-mediated immune recognition and osteoinduction initiated by the implantation of biomaterials.
BIK1 protein homeostasis is maintained by the interplay of different ubiquitin ligases in immune signaling.
FOXA1 O-GlcNAcylation-mediated transcriptional switch governs metastasis capacity in breast cancer.
Increased NMDARs in neurons and glutamine synthetase in astrocytes underlying autistic-like behaviors of Gabrb1(-/-) mice.
STING-IRG1 inhibits liver metastasis of colorectal cancer by regulating the polarization of tumor-associated macrophages.
Magneto-mechanical stimulation modulates osteocyte fate via the ECM-integrin-CSK axis and wnt pathway.
PAK1 contributes to cerebral ischemia/reperfusion injury by regulating the blood-brain barrier integrity.
Advanced oxidation protein products induce Paneth cells defects by endoplasmic reticulum stress in Crohn's disease.
O-GlcNAcylation of Raptor transduces glucose signals to mTORC1.
Comprehensive characterization of pyroptosis phenotypes with distinct tumor immune profiles in gastric cancer to aid immunotherapy.
N-Linked Glycosylation and Expression of Duck Plague Virus pUL10 Promoted by pUL49.5.
Piscine Vitamin D Receptors Vdra/Vdrb in the Absence of Vitamin D Are Utilized by Grass Carp Reovirus for Promoting Viral Replication.
A Recombinant Duck Plague Virus Containing the ICP27 Deletion Marker Provides Robust Protection in Ducks.
ATP6V1F is a novel prognostic biomarker and potential immunotherapy target for hepatocellular carcinoma.
Integrin β(3) directly inhibits the Gα(13)-p115RhoGEF interaction to regulate G protein signaling and platelet exocytosis.
Hedyotis diffusa-Sculellaria barbata (HD-SB) suppresses the progression of colorectal cancer cells via the hsa_circ_0039933/hsa-miR-204-5p/wnt11 axis.
Berberine modulates gut microbiota to attenuate cerebral ferroptosis induced by ischemia-reperfusion in mice.
Dihydromyricetin attenuates cisplatin-induced acute kidney injury by reducing oxidative stress, inflammation and ferroptosis.
Analyzing roles of small nucleolar RNA host gene 25 from clinical, molecular target and tumor formation in prostate cancer.
Methionine orchestrates the metabolism vulnerability in cisplatin resistant bladder cancer microenvironment.
The RNA-binding protein KSRP aggravates malignant progression of clear cell renal cell carcinoma through transcriptional inhibition and post-transcriptional destabilization of the NEDD4L ubiquitin ligase.
Systemic Mutation of Ncf1 Ameliorates Obstruction-Induced Renal Fibrosis While Macrophage-Rescued NCF1 Further Alleviates Renal Fibrosis.
Targeted Protein Degradation through Recruitment of the CUL4A Complex Adaptor Protein DDB1.
Taraxasterol suppresses the proliferation and tumor growth of androgen-independent prostate cancer cells through the FGFR2-PI3K/AKT signaling pathway.
Identification of Selective ATP-Competitive CMG Helicase Inhibitors for Cancer Intervention that Disrupt CMG-Replisome Function.
Simiao San alleviates hyperuricemia and kidney inflammation by inhibiting NLRP3 inflammasome and JAK2/STAT3 signaling in hyperuricemia mice.
Loganin alleviated cognitive impairment in 3×Tg-AD mice through promoting mitophagy mediated by optineurin.
Interaction of Bmal1 and eIF2α/ATF4 pathway was involved in Shuxie compound alleviation of circadian rhythm disturbance-induced hepatic endoplasmic reticulum stress.
A novel mechanism regulating pyroptosis-induced fibrosis in endometriosis via lnc-MALAT1/miR-141-3p/NLRP3 pathway†.
Bellidifolin ameliorates isoprenaline-induced cardiac hypertrophy by the Nox4/ROS signalling pathway through inhibiting BRD4.
PRMT4 Facilitates White Adipose Tissue Browning and Thermogenesis by Methylating PPARγ.
SUPPLEMENTATION WITH NICOTINAMIDE RIBOSIDE ATTENUATES T CELL EXHAUSTION AND IMPROVES SURVIVAL IN SEPSIS.
Dibutyl phthalate induces epithelial-mesenchymal transition of renal tubular epithelial cells via the Ang II/AMPKα2/Cx43 signaling pathway.
Mucin2 regulated by Ho1/p38/IL-10 axis plays a protective role in polystyrene nanoplastics-mediated intestinal toxicity.
miR-342-5p promotes vascular smooth muscle cell phenotypic transition through a negative-feedback regulation of Notch signaling via targeting FOXO3.
Inhibition of glycolysis prevents behavioural changes in mice with MK801-induced SCZ model by alleviating lactate accumulation and lactylation.
PARP16-Mediated Stabilization of Amyloid Precursor Protein mRNA Exacerbates Alzheimer's Disease Pathogenesis.
Dexmedetomidine Pretreatment Protects Against Myocardial Ischemia/Reperfusion Injury by Activating STAT3 Signaling.
High-intensity interval training improves fatty infiltration in the rotator cuff through the β3 adrenergic receptor in mice.
A cell-autonomous mechanism regulates BCAA catabolism in white adipocytes and systemic metabolic balance.
Prenatally VPA exposure is likely to cause autistic-like behavior in the rats offspring via TREM2 down-regulation to affect the microglial activation and synapse alterations.
HSV-1 infection-induced herpetic neuralgia involves a CCL5/CCR5-mediated inflammation mechanism.
LncRNA-PEAK1 promotes neuronal apoptosis after intracerebral hemorrhage by miR-466i-5p/caspase 8 axis.
Thrombospondin-1 mimic peptide PKHB1 induced endoplasmic reticulum stress-mediated but CD47-independent apoptosis in non-small cell lung cancer.
Oridonin ameliorates acetaminophen-induced acute liver injury through ATF4/PGC-1α pathway.
SARS-CoV-2 restructures host chromatin architecture.
LINC00115 regulates lung adenocarcinoma progression via sponging miR-154-3p to modulate Sp3 expression.
Long-Term High-Fat Diet Decreases Renal Insulin-Degrading Enzyme Expression and Function by Inhibiting the PPARγ Pathway.
Daurisoline suppresses esophageal squamous cell carcinoma growth in vitro and in vivo by targeting MEK1/2 kinase.
SNORD60 promotes the tumorigenesis and progression of endometrial cancer through binding PIK3CA and regulating PI3K/AKT/mTOR signaling pathway.
HnRNP K reduces viral gene expression by targeting cytosine-rich sequences in porcine reproductive and respiratory syndrome virus-2 genome to dampen the viral growth.
Changes in N6-methyladenosine RNA methylomes of human periodontal ligament cells in response to inflammatory conditions.
Effects of phase-transited lysozyme on adhesion, migration and odontogenic differentiation of human dental pulp cells: An in vitro study.
Bipotent transitional liver progenitor cells contribute to liver regeneration.
YBX1 regulates the survival of chronic myeloid leukemia stem cells by modulating m(6)A-mediated YWHAZ stability.
Hyperthermia promotes degradation of the acute promyelocytic leukemia driver oncoprotein ZBTB16/RARα.
Regulation of CD8(+) T cells infiltration and immunotherapy by circMGA/HNRNPL complex in bladder cancer.
Muscone promotes functional recovery by facilitating microglia polarization into M2 phenotype through PPAR-γ pathway after ischemic stroke.
Identification of the CCL2 PI3K/Akt axis involved in autophagy and apoptosis after spinal cord injury.
p53 inhibits the Urea cycle and represses polyamine biosynthesis in glioma cell lines.
Deletion of the tyrosine phosphatase Shp2 in cervical cancer cells promotes reprogramming of glutamine metabolism.
Kcnma1 is involved in mitochondrial homeostasis in diabetes-related skeletal muscle atrophy.
Renal CD81 interacts with sodium potassium 2 chloride cotransporter and sodium chloride cotransporter in rats with lipopolysaccharide-induced preeclampsia.
Protective Roles of Xijiao Dihuang Tang on Coronary Artery Injury in Kawasaki Disease.
MiR-155 promotes inflammation and apoptosis via targeting SIRT1 in hypoxic-ischemic brain damage.
Circular RNA circFBXO7 attenuates non-small cell lung cancer tumorigenesis by sponging miR-296-3p to facilitate KLF15-mediated transcriptional activation of CDKN1A.
The aryl sulfonamide indisulam inhibits gastric cancer cell migration by promoting the ubiquitination and degradation of the transcription factor ZEB1.
Hypermethylation of HIC2 is a potential prognostic biomarker and tumor suppressor of glioma based on bioinformatics analysis and experiments.
METTL3/14 and IL-17 signaling contribute to CEBPA-DT enhanced oral cancer cisplatin resistance.
MicroRNAs of extracellular vesicles derived from mesenchymal stromal cells alleviate inflammation in dry eye disease by targeting the IRAK1/TAB2/NF-κB pathway.
Kaempferol promotes melanogenesis and reduces oxidative stress in PIG1 normal human skin melanocytes.
LPS inhibits TRIM65 expression in macrophages and C57BL/6J mouse by activating the ERK1/2 signaling pathway.
DAB2 promotes pulmonary fibrosis and may act as an intermediate between IGF‑1R and PI3K/AKT signaling pathways.
Protective effect of L‑carnitine against oxidative stress injury in human ovarian granulosa cells.
Doublecortin-like kinase 2 promotes breast cancer cell invasion and metastasis.
Inhibition of mitochondrial VDAC1 oligomerization alleviates apoptosis and necroptosis of retinal neurons following OGD/R injury.
Geranylgeranylacetone-induced heat shock protein70 expression reduces retinal ischemia-reperfusion injury through PI3K/AKT/mTOR signaling.
Osteogenic and anti-inflammatory effects of SLA titanium substrates doped with chitosan-stabilized selenium nanoparticles via a covalent coupling strategy.
RNA-Seq-based transcriptomics analysis during the photodynamic therapy of primary cells in secondary hyperparathyroidism.
Poly-L-Lactic acid increases collagen gene expression and synthesis in cultured dermal fibroblast (Hs68) through the TGF-β/Smad pathway.
Derivation and comprehensive analysis of ageing-related genes in intervertebral disc degeneration for prediction and immunology.
Nitrovin (difurazone), an antibacterial growth promoter, induces ROS-mediated paraptosis-like cell death by targeting thioredoxin reductase 1 (TrxR1).
CCL17 drives fibroblast activation in the progression of pulmonary fibrosis by enhancing the TGF-β/Smad signaling.
The RSK2-RPS6 axis promotes axonal regeneration in the peripheral and central nervous systems.
Effects of Selenoprotein S Knockdown on Endoplasmic Reticulum Stress in ATDC5 Cells and Gene Expression Profiles in Hypertrophic Chondrocytes.
TSG-6 inhibits hypertrophic scar fibroblast proliferation by regulating IRE1α/TRAF2/NF-κB signalling.
Mechanisms regarding respiratory toxicity triggered by accumulation of ROS in carp exposed to difenoconazole.
FOXP3+ macrophage represses acute ischemic stroke-induced neural inflammation.
FGFR2 upregulates PAI-1 via JAK2/STAT3 signaling to induce M2 polarization of macrophages in colorectal cancer.
CDC20 inhibition alleviates fibrotic response of renal tubular epithelial cells and fibroblasts by regulating nuclear translocation of β-catenin.
Vagus nerve stimulation is a potential treatment for ischemic stroke.
Hypoxic postconditioning restores mitophagy against transient global cerebral ischemia via Parkin-induced posttranslational modification of TBK1.
The Mechanism of the Anti-Cardiac Hypertrophy Effect of Glycyrrhizic Acid Is Related to Reducing STIM1-Dependent Store-Operated Calcium Entry.
1,3-dichloro-2-propanol caused lipid droplets accumulation by suppressing neutral lipases via BMAL1 in hepatocytes.
Repurposed benzydamine targeting CDK2 suppresses the growth of esophageal squamous cell carcinoma.
NETO2 promotes melanoma progression via activation of the Ca(2+)/CaMKII signaling pathway.
BMAL1 regulates MUC1 overexpression in ovalbumin-induced asthma.
Preparation of tanshinone II(A) self-soluble microneedles and its inhibition on proliferation of human skin fibroblasts.
P2X4 receptor modulates gut inflammation and favours microbial homeostasis in colitis.
Neutralization of interleukin-11 attenuates silica particles-induced pulmonary inflammation and fibrosis in vivo.
LINC00669 promotes lung adenocarcinoma growth by stimulating the Wnt/β-catenin signaling pathway.
Par14 interacts with the androgen receptor, augmenting both its transcriptional activity and prostate cancer proliferation.
Autophagy-mediated circHIPK2 promotes lipopolysaccharide-induced astrocytic inflammation via SIGMAR1.
Blockade of neutrophil extracellular traps ameliorates toluene diisocyanate-induced steroid-resistant asthma.
Suppression of androgen receptor signaling induces prostate cancer migration via activation of the CCL20-CCR6 axis.
Circular RNA circ0104103 inhibits colorectal cancer progression through interactions with HuR and miR-373-5p.
Salvianolic acid A alleviates atherosclerosis by inhibiting inflammation through Trc8-mediated 3-hydroxy-3-methylglutaryl-coenzyme A reductase degradation.
Chordoma recruits and polarizes tumor-associated macrophages via secreting CCL5 to promote malignant progression.
Genetic Knockout of Fatty Acid Amide Hydrolase Ameliorates Cisplatin-Induced Nephropathy in Mice.
Biomimetic Remodeling of Microglial Riboflavin Metabolism Ameliorates Cognitive Impairment by Modulating Neuroinflammation.
CDKAL1 Drives the Maintenance of Cancer Stem-Like Cells by Assembling the eIF4F Translation Initiation Complex.
EHBP1L1 Drives Immune Evasion in Renal Cell Carcinoma through Binding and Stabilizing JAK1.
Histone phosphorylation integrates the hepatic glucagon-PKA-CREB gluconeogenesis program in response to fasting.
SLFN5-mediated chromatin dynamics sculpt higher-order DNA repair topology.
Harnessing matrix stiffness to engineer a bone marrow niche for hematopoietic stem cell rejuvenation.
Homeobox A3 and KDM6A cooperate in transcriptional control of aerobic glycolysis and glioblastoma progression.
Protocatechuic aldehyde acts synergistically with dacarbazine to augment DNA double-strand breaks and promote apoptosis in cutaneous melanoma cells.
CMTR1 promotes colorectal cancer cell growth and immune evasion by transcriptionally regulating STAT3.
PRMT3-mediated arginine methylation of IGF2BP1 promotes oxaliplatin resistance in liver cancer.
Dihydrocaffeic acid improves IL-1β-induced inflammation and cartilage degradation via inhibiting NF-κB and MAPK signalling pathways.
Progranulin inhibits phospholipase sPLA2-IIA to control neuroinflammation.
PFO5DoDA disrupts hepatic homeostasis primarily through glucocorticoid signaling inhibition.
Goliath induces inflammation in obese mice by linking fatty acid β-oxidation to glycolysis.
Epitranscriptic regulation of HRAS by N(6)-methyladenosine drives tumor progression.
Anti-inflammatory effect of Irisin on LPS-stimulated macrophages through inhibition of MAPK pathway.
Transcriptomic analysis: the protection of over-expression thioredoxin reductase 1 in Parkinson's disease.
DNA damage repair kinase DNA-PK and cGAS synergize to induce cancer-related inflammation in glioblastoma.
Persistent Lipid Accumulation Leads to Persistent Exacerbation of Endoplasmic Reticulum Stress and Inflammation in Progressive NASH via the IRE1α/TRAF2 Complex.
The outer mitochondrial membrane protein TMEM11 demarcates spatially restricted BNIP3/BNIP3L-mediated mitophagy.
Downregulation of AC092894.1 promotes oxaliplatin resistance in colorectal cancer via the USP3/AR/RASGRP3 axis.
Crotonylation of GAPDH regulates human embryonic stem cell endodermal lineage differentiation and metabolic switch.
Upregulation of carbonic anhydrase 1 beneficial for depressive disorder.
Glucose Transporter Glut1-Dependent Metabolic Reprogramming Regulates Lipopolysaccharide-Induced Inflammation in RAW264.7 Macrophages.
DEAD-Box Helicase 17 Promotes Amyloidogenesis by Regulating BACE1 Translation.
Synthesis of Lathyrol PROTACs and Evaluation of Their Anti-Inflammatory Activities.
LncRNA NR_003508 Suppresses Mycobacterium tuberculosis-Induced Programmed Necrosis via Sponging miR-346-3p to Regulate RIPK1.
8-Methoxyflindersine-Induced Apoptosis and Cell Cycle Disorder Involving MAPK Signaling Activation in Human Colorectal Cancer Cells.
Design, Synthesis, and Antitumor Activity of Potent and Selective EGFR L858R/T790M Inhibitors and Identification of a Combination Therapy to Overcome Acquired Resistance in Models of Non-small-cell Lung Cancer.
Development of Orally Bioavailable Amidobenzimidazole Analogues Targeting Stimulator of Interferon Gene (STING) Receptor.
Repurposing of Doramectin as a New Anti-Zika Virus Agent.
NSC-derived exosomes enhance therapeutic effects of NSC transplantation on cerebral ischemia in mice.
Sleep deprivation exacerbates microglial reactivity and Aβ deposition in a TREM2-dependent manner in mice.
YTHDF1 phase separation triggers the fate transition of spermatogonial stem cells by activating the IκB-NF-κB-CCND1 axis.
Nuclear ATR lysine-tyrosylation protects against heart failure by activating DNA damage response.
PPDPF suppresses the development of hepatocellular carcinoma through TRIM21-mediated ubiquitination of RIPK1.
Chromatin Remodelling Molecule ARID1A Determines Metastatic Heterogeneity in Triple-Negative Breast Cancer by Competitively Binding to YAP.
Strategy To Assess Zoonotic Potential Reveals Low Risk Posed by SARS-Related Coronaviruses from Bat and Pangolin.
Production of mature myotubes in vitro improves the texture and protein quality of cultured pork.
CHST2-mediated sulfation of MECA79 antigens is critical for breast cancer cell migration and metastasis.
RBM4 dictates ESCC cell fate switch from cellular senescence to glutamine-addiction survival through inhibiting LKB1-AMPK-axis.
FUT1-mediated terminal fucosylation acts as a new target to attenuate renal fibrosis.
Progesterone prevents HGSOC by promoting precancerous cell pyroptosis via inducing fibroblast paracrine.
Effects of lysate/tissue storage at -80°C on subsequently extracted EVs of epithelial ovarian cancer tissue origins.
JLP/Foxk1/N-cadherin axis fosters a partial epithelial-mesenchymal transition state in epithelial tubular cells.
Network pharmacology and experimental validation to reveal the target of matrine against PRRSV.
AC010883.5 promotes cell proliferation, invasion, migration, and epithelial-to-mesenchymal transition in cervical cancer by modulating the MAPK signaling pathway.
Gab2 plays a carcinogenic role in ovarian cancer by regulating CrkII.
[Overexpression of miR-431-5p impairs mitochondrial function and induces apoptosis in gastric cancer cells via the Bax/Bcl-2/caspase3 pathway].
Chemoproteomics-enabled discovery of a covalent molecular glue degrader targeting NF-κB.
Host E3 ligase Hrd1 ubiquitinates and degrades H protein of canine distemper virus to inhibit viral replication.
PHF14 enhances DNA methylation of SMAD7 gene to promote TGF-β-driven lung adenocarcinoma metastasis.
Promoted Skin Wound Healing by Tail-Amputated Eisenia foetida Proteins via the Ras/Raf/MEK/ERK Signaling Pathway.
VEGFA mRNA-LNP promotes biliary epithelial cell-to-hepatocyte conversion in acute and chronic liver diseases and reverses steatosis and fibrosis.
Effect of Matrix Metalloproteinase 23 Accelerating Wound Healing Induced by Hydroxybutyl Chitosan.
Cadmium-induced Sertoli Cell Injury Through p38-MAPK and Related Signaling Proteins-A Study by RNA Sequencing.
Human cytomegalovirus attenuates AKT activity by destabilizing insulin receptor substrate proteins.
Upregulated estrogen receptors impairs myogenesis and elevates adipogenesis related factor levels in the paravertebral muscles of patients with idiopathic scoliosis.
Prolyl isomerase Pin1 promotes extracellular matrix production in hepatic stellate cells through regulating formation of the Smad3-TAZ complex.
DJ-1 Protects auditory cells from cisplatin-induced ototoxicity via regulating apoptosis and autophagy.
Galectin-1 Regulates RNA Expression and Alternative Splicing of Angiogenic Genes in HUVECs.
Design and Synthesis of Triazole-Containing HDAC Inhibitors That Induce Antitumor Effects and Immune Response.
DDB1 regulates the activation-induced apoptosis of T cells via downregulating the expression of histone methyltransferase SETD7.
LCRMP-1 is required for spermatogenesis and stabilises spermatid F-actin organization via the PI3K-Akt pathway.
Tenascin C(+) papillary fibroblasts facilitate neuro-immune interaction in a mouse model of psoriasis.
Knockout of murine Lyplal1 confers sex-specific protection against diet-induced obesity.
Development of Engineered CAR T Cells Targeting Tumor-Associated Glycoforms of MUC1 for the Treatment of Intrahepatic Cholangiocarcinoma.
Aristolochic acid I promotes the invasion and migration of hepatocellular carcinoma cells by activating the C3a/C3aR complement system.
Exosomal circCLIP1 regulates PM(2.5)-induced airway obstruction via targeting SEPT10 in vitro.
3,4-benzopyrene aggravates myocardial ischemia-reperfusion injury-induced pyroptosis through inhibition of autophagy-dependent NLRP3 degradation.
SGLT2i alleviates epicardial adipose tissue inflammation by modulating ketone body-glyceraldehyde-3-phosphate dehydrogenase malonylation pathway.
Precise pancreatic cancer therapy through targeted degradation of mutant p53 protein by cerium oxide nanoparticles.
Gold nanoclusters conjugated berberine reduce inflammation and alleviate neuronal apoptosis by mediating M2 polarization for spinal cord injury repair.
Prognostic value of plasma adipokine chemerin in patients with coronary artery disease.
Collagen peptide promotes DSS-induced colitis by disturbing gut microbiota and regulation of macrophage polarization.
Endothelial G protein stimulatory α-subunit is a critical regulator of post-ischemic angiogenesis.
A rare case of arrhythmogenic right ventricular cardiomyopathy associated with LAMA2 mutation: A case report and literature review.
ACSL3 is a potential prognostic biomarker for immune infiltration in clear cell renal cell carcinoma.
A Prognostic Signature Consisting of Pyroptosis-Related Genes and SCAF11 for Predicting Immune Response in Breast Cancer.
Research on the Mechanism and Prevention of Hypertension Caused by Apatinib Through the RhoA/ROCK Signaling Pathway in a Mouse Model of Gastric Cancer.
Galectin-3 Inhibition Ameliorates Streptozotocin-Induced Diabetic Cardiomyopathy in Mice.
Whole-Exome Sequencing Identifies a Novel Variant (c.1538T > C) of TNNI3K in Arrhythmogenic Right Ventricular Cardiomyopathy.
Green Banana Flour Contributes to Gut Microbiota Recovery and Improves Colonic Barrier Integrity in Mice Following Antibiotic Perturbation.
Metformin Promotes Mechanical Stretch-Induced Skin Regeneration by Improving the Proliferative Activity of Skin-Derived Stem Cells.
Establishment of a New Abdominal Aortic Aneurysm Model in Rats by a Retroperitoneal Approach.
Bilateral Superior Cervical Sympathectomy Activates Signal Transducer and Activator of Transcription 3 Signal to Alleviate Myocardial Ischemia-Reperfusion Injury.
Integrated Strategies of Diverse Feature Selection Methods Identify Aging-Based Reliable Gene Signatures for Ischemic Cardiomyopathy.
Exploring the Mechanism of Hawthorn Leaves Against Coronary Heart Disease Using Network Pharmacology and Molecular Docking.
Comprehensive Characterization of Ageing-Relevant Subtypes Associated With Different Tumorigenesis and Tumor Microenvironment in Prostate Cancer.
Bioinformatics-Guided Analysis Uncovers AOX1 as an Osteogenic Differentiation-Relevant Gene of Human Mesenchymal Stem Cells.
Hypoglycemia-Exacerbated Mitochondrial Connexin 43 Accumulation Aggravates Cardiac Dysfunction in Diabetic Cardiomyopathy.
SS31 Ameliorates Oxidative Stress via the Restoration of Autophagic Flux to Protect Aged Mice From Hind Limb Ischemia.
Exosome-Derived From Sepsis Patients' Blood Promoted Pyroptosis of Cardiomyocytes by Regulating miR-885-5p/HMBOX1.
IL-7-Treated Periodontal Ligament Cells Regulate Local Immune Homeostasis by Modulating Treg/Th17 Cell Polarization.
CTB-193M12.5 Promotes Hepatocellular Carcinoma Progression via Enhancing NSD1-Mediated WNT10B/Wnt/β-Catenin Signaling Activation.
RNA Binding Motif Protein 3 Promotes Cell Metastasis and Epithelial-Mesenchymal Transition Through STAT3 Signaling Pathway in Hepatocellular Carcinoma.
Ticagrelor reduces doxorubicin-induced pyroptosis of rat cardiomyocytes by targeting GSK-3β/caspase-1.
miRNA-150_R-1 mediates the HIF-1/ErbB signaling pathway to regulate the adhesion of endometrial epithelial cells in cows experiencing retained placenta.
Triptolide increases resistance to bile duct ligation-induced liver injury and fibrosis in mice by inhibiting RELB.
Enhanced pathogenicity by up-regulation of A20 after avian leukemia subgroup a virus infection.
Hydrogen sulfide against preeclampsia exposure-induced oxidative mitochondrial damage in HTR-8/SVneo cells.
Effects of insufficient serine on health and selenoprotein expression in rats and their offspring.
Regulation of the Human IL-10RB Gene Expression by Sp8 and Sp9.
Ubiquitin‑specific peptidase 53 promotes chronic constriction injury‑induced neuropathic pain through the RhoA/ROCK pathway.
MicroRNA-128b mediates lipopolysaccharide-induced apoptosis via reactive oxygen species in human pulmonary microvascular endothelial cells.
Paradol Induces Cell Cycle Arrest and Apoptosis in Glioblastoma Cells.
Astragaloside IV drug-loaded exosomes (AS-IV EXOs) derived from endothelial progenitor cells improve the viability and tube formation in high-glucose impaired human endothelial cells by promoting miR-214 expression.
7-Methylxanthine Influences the Behavior of ADORA2A-DRD2 Heterodimers in Human Retinal Pigment Epithelial Cells.
Identification and Verification of Ubiquitin D as a Gene Associated with Hepatitis C Virus-Induced Hepatocellular Carcinoma.
MiR-7015-3p Targets Nuclear Factor-Kappa-B-Inhibitor Alpha to Aggravate Hypoxia/Reoxygenation Injury in Cardiomyocytes Through the NF-κB Pathway.
Sinapic Acid Alleviates Acute Pancreatitis in Association with Attenuation of Inflammation, Pyroptosis, and the AMPK/NF-[Formula: see text]B Signaling Pathway.
Bovine milk exosomes affected proliferation of macrophages under hypoxia.
Demethylase FTO inhibits the development of prostate cancer by upregulating EGR2 expression in an m6A manner.
ETV6 Regulates Hemin-Induced Erythroid Differentiation of K562 Cells through Mediating the Raf/MEK/ERK Pathway.
Torin1 restores proliferation rate in Charcot-Marie-Tooth disease type 2A cells harbouring MFN2 (mitofusin 2) mutation.
Regulation of lysosomal trafficking of progranulin by sortilin and prosaposin.
Hyperthermia promotes exosome secretion by regulating Rab7b while increasing drug sensitivity in adriamycin-resistant breast cancer.
Gynura segetum induces hepatic sinusoidal obstruction syndrome in mice by impairing autophagy.
Human mesenchymal stem cell derived exosomes inhibit the survival of human melanoma cells through modulating miR-138-5p/SOX4 pathway.
Ubiquitination and degradation of MGMT by TRIM72 increases the sensitivity of uveal melanoma cells to Dacarbazine treatment.
Non-canonical Small GTPase RBJ Promotes NSCLC Progression Through the Canonical MEK/ERK Signaling Pathway.
IL-33 Participates in the Development of Esophageal Adenocarcinoma.
Activated Hepatic Stellate Cells Promote the M1 to M2 Macrophage Transformation and Liver Fibrosis by Elevating the Histone Acetylation Level.
Targeting the LSD1-G9a-ER Stress Pathway as a Novel Therapeutic Strategy for Esophageal Squamous Cell Carcinoma.
Downregulation of HULC Induces Ferroptosis in Hepatocellular Carcinoma via Targeting of the miR-3200-5p/ATF4 Axis.
Experimental Study on the Mechanism of Cinnamaldehyde Ameliorate Proteinuria Induced by Adriamycin.
Huoxue Qianyang Qutan Recipe Protects against Early Renal Damage Induced by Obesity-Related Hypertension via the SIRT1/NF-κB/IL-6 Pathway: Integrating Network Pharmacology and Experimental Validation-Based Strategy.
Guanxinping Tablets Inhibit ET-1-Induced Proliferation and Migration of MOVAS by Suppressing Activated PI3K/Akt/NF-κB Signaling Cascade.
Tiaojing Cuyun Recipe Enhances Pregnancy Outcome via the VEGF/PI3K/AKT/eNOS Signaling Pathway in EID Mice.
Identification and Characterization of the Roles of circCASP9 in Gastric Cancer Based on a circRNA-miRNA-mRNA Regulatory Network.
Loureirin B Alleviates Myocardial Ischemia/Reperfusion Injury via Inhibiting PAI-1/TGF-β1/Smad Signaling Pathway.
Scrapie-Responsive Gene 1 Promotes Chondrogenic Differentiation of Umbilical Cord Mesenchymal Stem Cells via Wnt5a.
Cell-Dependent Pathogenic Roles of Filamin B in Different Skeletal Malformations.
Ketamine Promotes LPS-Induced Pulmonary Autophagy and Reduces Apoptosis through the AMPK/mTOR Pathway.
LncRNA-MALAT1 Regulates Cancer Glucose Metabolism in Prostate Cancer via MYBL2/mTOR Axis.
Dihydroartemisinin Attenuated Intervertebral Disc Degeneration via Inhibiting PI3K/AKT and NF-κB Signaling Pathways.
Pretreatment with Shenmai Injection Protects against Coronary Microvascular Dysfunction.
Nr2f2 Overexpression Aggravates Ferroptosis and Mitochondrial Dysfunction by Regulating the PGC-1α Signaling in Diabetes-Induced Heart Failure Mice.
Exosomes Derived from Baicalin-Pretreated Mesenchymal Stem Cells Alleviate Hepatocyte Ferroptosis after Acute Liver Injury via the Keap1-NRF2 Pathway.
Targeting Circulating lncRNA ENST00000538705.1 Relieves Acute Coronary Syndrome via Modulating ALOX15.
AdipoR1 Regulates Ionizing Radiation-Induced Ferroptosis in HCC cells through Nrf2/xCT Pathway.
circIFT80 Functions as a ceRNA for miR-142, miR-568, and miR-634 and Promotes the Progression of Colorectal Cancer by Targeting β-Catenin.
The Overexpression of TOB1 Induces Autophagy in Gastric Cancer Cells by Secreting Exosomes.
Effects of Escin on Oxidative Stress and Apoptosis of H9c2 Cells Induced by H(2)O(2).
Network Pharmacology Prediction and Molecular Docking-Based Strategy to Discover the Potential Pharmacological Mechanism of Wen-Yu-Jin against Pulmonary Fibrosis in a Mouse Model.
HOTAIRM1 Maintained the Malignant Phenotype of tMSCs Transformed by GSCs via E2F7 by Binding to FUS.
Dexmedetomidine Can Enhance PINK1/Parkin-Mediated Mitophagy in MPTP-Induced PD Mice Model by Activating AMPK.
Calycosin Improves Intestinal Mucosal Barrier Function after Gastrectomy in Rats through Alleviating Bacterial Translocation, Inflammation, and Oxidative Stress.
TRIP13 Induces Nedaplatin Resistance in Esophageal Squamous Cell Carcinoma by Enhancing Repair of DNA Damage and Inhibiting Apoptosis.
Protective Effect of Photobiomodulation against Hydrogen Peroxide-Induced Oxidative Damage by Promoting Autophagy through Inhibition of PI3K/AKT/mTOR Pathway in MC3T3-E1 Cells.
APY0201 Represses Tumor Growth through Inhibiting Autophagy in Gastric Cancer Cells.
Catalpol Regulates Oligodendrocyte Regeneration and Remyelination by Activating the GEF-Cdc42/Rac1 Signaling Pathway in EAE Mice.
Aspirin Exerts Its Antitumor Effect in Esophageal Squamous Cell Carcinoma by Downregulating the Expression of ATAD2 and KIF4A.
Mechanical Stretch Promotes Macrophage Polarization and Inflammation via the RhoA-ROCK/NF-κB Pathway.
Bellidifolin Inhibits SRY-Related High Mobility Group-Box Gene 9 to Block TGF-β Signalling Activation to Ameliorate Myocardial Fibrosis.
Interleukin-19 Aggravates Pulmonary Fibrosis via Activating Fibroblast through TGF-β/Smad Pathway.
Exploring and Verifying the Mechanism and Targets of Shenqi Pill in the Treatment of Nonalcoholic Steatohepatitis via Network Pharmacology and Experiments.
miR-373-3p Regulates the Proliferative and Migratory Properties of Human HTR8 Cells via SLC38A1 Modulation.
Integrated Analysis of the Role of Enolase 2 in Clear Cell Renal Cell Carcinoma.
PFKFB3 Increases IL-1β and TNF-α in Intestinal Epithelial Cells to Promote Tumorigenesis in Colitis-Associated Colorectal Cancer.
Exosomes Derived from SW480-Resistant Colon Cancer Cells Are Promote Angiogenesis via BMP-2/Smad5 Signaling Pathway.
Paeoniflorin Regulates NEDD4L/STAT3 Pathway to Induce Ferroptosis in Human Glioma Cells.
Huaier Inhibits Gastric Cancer Growth and Hepatic Metastasis by Reducing Syntenin Expression and STAT3 Phosphorylation.
Aloin Regulates Matrix Metabolism and Apoptosis in Human Nucleus Pulposus Cells via the TAK1/NF-κB/NLRP3 Signaling Pathway.
Combination of Perindopril Erbumine and Huangqi-Danshen Decoction Protects Against Chronic Kidney Disease via Sirtuin3/Mitochondrial Dynamics Pathway.
Hepatoprotective Role of 4-Octyl Itaconate in Concanavalin A-Induced Autoimmune Hepatitis.
Cigarette Smoke Exposure Increases Glucose-6-phosphate Dehydrogenase, Autophagy, Fibrosis, and Senescence in Kidney Cells In Vitro and In Vivo.
IFN-γ induces PD-L1 through p38/JNK/ERK signaling pathways and counteracts the tumor promoting effect mediated by PD-L1 in Glioblastoma.
ASPM Promotes the Progression of Anaplastic Thyroid Carcinomas by Regulating the Wnt/β-Catenin Signaling Pathway.
CYP26A1 Is a Novel Cancer Biomarker of Pancreatic Carcinoma: Evidence from Integration Analysis and In Vitro Experiments.
Deletion of ACLY Disrupts Histone Acetylation and IL-10 Secretion in Trophoblasts, Which Inhibits M2 Polarization of Macrophages: A Possible Role in Recurrent Spontaneous Abortion.
LOX and Its Methylation Impact Prognosis of Diseases and Correlate with TAM Infiltration in ESCA.
MKK4 Knockdown Plays a Protective Role in Hemorrhagic Shock-Induced Liver Injury through the JNK Pathway.
Explore the Mechanism of Astragalus mongholicus Bunge against Nonalcoholic Fatty Liver Disease Based on Network Pharmacology and Experimental Verification.
Vitamin D3 Supplementation Attenuates Surgery-Induced Neuroinflammation and Cognitive Impairment by Regulating NLRP3 Inflammasome in Mice.
Antitumor Effect of Si-Jun-Zi Decoction on SGC7901 Gastric Cancer Cells by CMTM2 Activation.
Qizhi Kebitong Formula Ameliorates Streptozocin-Induced Diabetic Osteoporosis through Regulating the PI3K/Akt/NF-κB Pathway.
Identification and Validation of Ferroptosis-Related Genes in Sevoflurane-Induced Hippocampal Neurotoxicity.
Schwann Cells Accelerate Osteogenesis via the Mif/CD74/FOXO1 Signaling Pathway In Vitro.
4,7-Didehydro-neophysalin B Protects Rat Lung Epithelial Cells against Hydrogen Peroxide-Induced Oxidative Damage through Nrf2-Mediated Signaling Pathway.
The Long Noncoding Transcript HNSCAT1 Activates KRT80 and Triggers Therapeutic Efficacy in Head and Neck Squamous Cell Carcinoma.
Acetylation of Atp5f1c Mediates Cardiomyocyte Senescence via Metabolic Dysfunction in Radiation-Induced Heart Damage.
CCAAT/Enhancer-Binding Protein Delta Regulates Glioblastoma Survival through Catalase-Mediated Hydrogen Peroxide Clearance.
Eugenol-Preconditioned Mesenchymal Stem Cell-Derived Extracellular Vesicles Promote Antioxidant Capacity of Tendon Stem Cells In Vitro and In Vivo.
HIF-1α Regulates the Progression of Cervical Cancer by Targeting YAP/TAZ.
Lycopene Improves Bone Quality and Regulates AGE/RAGE/NF-кB Signaling Pathway in High-Fat Diet-Induced Obese Mice.
Isorhamnetin Attenuated the Release of Interleukin-6 from β-Amyloid-Activated Microglia and Mitigated Interleukin-6-Mediated Neurotoxicity.
Metformin Protects against Spinal Cord Injury and Cell Pyroptosis via AMPK/NLRP3 Inflammasome Pathway.
Extracellular Vesicles of Mesenchymal Stem Cells Are More Effectively Accessed through Polyethylene Glycol-Based Precipitation than by Ultracentrifugation.
p16(INK4a) Plays Critical Role in Exacerbating Inflammaging in High Fat Diet Induced Skin.
FBXW7 Reduces the Cancer Stem Cell-Like Properties of Hepatocellular Carcinoma by Regulating the Ubiquitination and Degradation of ACTL6A.
Biochanin A Suppresses Tumor Progression and PD-L1 Expression via Inhibiting ZEB1 Expression in Colorectal Cancer.
Cyclic Polypeptide D7 Protects Bone Marrow Mesenchymal Cells and Promotes Chondrogenesis during Osteonecrosis of the Femoral Head via Growth Differentiation Factor 15-Mediated Redox Signaling.
Nicandra physalodes Extract Exerts Antiaging Effects in Multiple Models and Extends the Lifespan of Caenorhabditis elegans via DAF-16 and HSF-1.
Study on the Potential Mechanism of Semen Strychni against Myasthenia Gravis Based on Network Pharmacology and Molecular Docking with Experimental Verification.
Rapamycin Attenuates Anxiety and Depressive Behavior Induced by Helicobacter pylori in Association with Reduced Circulating Levels of Ghrelin.
Baicalin Ameliorates DSS-Induced Colitis by Protecting Goblet Cells through Activating NLRP6 Inflammasomes.
Hinokitiol Protects Cardiomyocyte from Oxidative Damage by Inhibiting GSK3β-Mediated Autophagy.
(-)-Epicatechin Reduces Neuroinflammation, Protects Mitochondria Function, and Prevents Cognitive Impairment in Sepsis-Associated Encephalopathy.
Streptococcus lutetiensis Induces Autophagy via Oxidative Stress in Bovine Mammary Epithelial Cells.
GSDME Increases Chemotherapeutic Drug Sensitivity by Inducing Pyroptosis in Retinoblastoma Cells.
Stage-Dependent Regulation of Dental Pulp Stem Cell Odontogenic Differentiation by Transforming Growth Factor-β1.
Exercise and Metformin Intervention Prevents Lipotoxicity-Induced Hepatocyte Apoptosis by Alleviating Oxidative and ER Stress and Activating the AMPK/Nrf2/HO-1 Signaling Pathway in db/db Mice.
Enamel Matrix Derivative Enhances the Odontoblastic Differentiation of Dental Pulp Stem Cells via Activating MAPK Signaling Pathways.
Idol Depletion Protects against Spontaneous Atherosclerosis in a Hamster Model of Familial Hypercholesterolemia.
Honokiol Ameliorates DSS-Induced Mouse Colitis by Inhibiting Inflammation and Oxidative Stress and Improving the Intestinal Barrier.
Sirt1 Mediates Vitamin D Deficiency-Driven Gluconeogenesis in the Liver via mTorc2/Akt Signaling.
DRDB: A Machine Learning Platform to Predict Chemical-Protein Interactions towards Diabetic Retinopathy.
Lignans from Mosla scabra Ameliorated Influenza A Virus-Induced Pneumonia via Inhibiting Macrophage Activation.
Aberrant Expression of Mitochondrial SAM Transporter SLC25A26 Impairs Oocyte Maturation and Early Development in Mice.
Tangshenning Attenuates High Glucose-Induced Podocyte Injury via Restoring Autophagy Activity through Inhibiting mTORC1 Activation.
Upregulated LINC00922 Promotes Epithelial-Mesenchymal Transition and Indicates a Dismal Prognosis in Gastric Cancer.
Qufeng Xuanbi Formula Ameliorates Airway Remodeling in Asthmatic Mice by Suppressing Airway Smooth Muscle Cell Proliferation through MEK/ERK Signaling Pathway.
Repeated Yueju, But Not Fluoxetine, Induced Sustained Antidepressant Activity in a Mouse Model of Chronic Learned Helplessness: Involvement of CaMKII Signaling in the Hippocampus.
Hydrogen Sulfide Ameliorated High Choline-Induced Cardiac Dysfunction by Inhibiting cGAS-STING-NLRP3 Inflammasome Pathway.
Characterization of Acetylation of Histone H3 at Lysine 9 in the Trigeminal Ganglion of a Rat Trigeminal Neuralgia Model.
Protective Effects of Vitamin C against Neomycin-Induced Apoptosis in HEI-OC1 Auditory Cell.
Inhibition of GSDMD Activates Poly(ADP-ribosyl)ation and Promotes Myocardial Ischemia-Reperfusion Injury.
Honokiol Provides Cardioprotection from Myocardial Ischemia/Reperfusion Injury (MI/RI) by Inhibiting Mitochondrial Apoptosis via the PI3K/AKT Signaling Pathway.
Mechanism of Abelmoschus manihot L. in the Treatment of Contrast-Induced Nephropathy on the Basis of Network Pharmacology Analysis.
LIM Mineralization Protein-1 Enhances the Committed Differentiation of Dental Pulp Stem Cells through the ERK1/2 and p38 MAPK Pathways and BMP Signaling.
Loss-of-function Mutations K11E or E271K Lead to Novel Tumor Suppression, Implicate Nucleolar Helicase DDX24 Oncogenicity.
Egr1 confers protection against acetaminophen‑induced hepatotoxicity via transcriptional upregulating of Acaa2.
NUF2 Drives Clear Cell Renal Cell Carcinoma by Activating HMGA2 Transcription through KDM2A-mediated H3K36me2 Demethylation.
UBE2S as a novel ubiquitinated regulator of p16 and β-catenin to promote bone metastasis of prostate cancer.
KLF4 Alleviates Hypertrophic Scar Fibrosis by Directly Activating BMP4 Transcription.
HERC3 directly targets RPL23A for ubiquitination degradation and further regulates Colorectal Cancer proliferation and the cell cycle.
The GR-gp78 Pathway is involved in Hepatic Lipid Accumulation Induced by Overexpression of 11β-HSD1.
Photobiomodulation Drives MiR-136-5p Expression to Promote Injury Repair after Myocardial Infarction.
Downregulation of lncRNA APCDD1L-AS1 due to DNA hypermethylation and loss of VHL protein expression promotes the progression of clear cell renal cell carcinoma.
TDG suppresses the migration and invasion of human colon cancer cells via the DNMT3A/TIMP2 axis.
Claudin-10 overexpression suppresses human clear cell renal cell carcinoma growth and metastasis by regulating ATP5O and causing mitochondrial dysfunction.
Melatonin reverses tumor necrosis factor-alpha-induced metabolic disturbance of human nucleus pulposus cells via MTNR1B/Gαi2/YAP signaling.
The RNF26/CBX7 axis modulates the TNF pathway to promote cell proliferation and regulate sensitivity to TKIs in ccRCC.
HB-EGF induces mitochondrial dysfunction via estrogen hypersecretion in granulosa cells dependent on cAMP-PKA-JNK/ERK-Ca(2+)-FOXO1 pathway.
Atractylenolide III ameliorates Non-Alcoholic Fatty Liver Disease by activating Hepatic Adiponectin Receptor 1-Mediated AMPK Pathway.
OTUD1 stabilizes PTEN to inhibit the PI3K/AKT and TNF-alpha/NF-kappaB signaling pathways and sensitize ccRCC to TKIs.
Hypoxic pancreatic cancer derived exosomal miR-30b-5p promotes tumor angiogenesis by inhibiting GJA1 expression.
As a Novel Tumor Suppressor, LHPP Promotes Apoptosis by Inhibiting the PI3K/AKT Signaling Pathway in Oral Squamous Cell Carcinoma.
ID09, A Newly-Designed Tubulin Inhibitor, Regulating the Proliferation, Migration, EMT Process and Apoptosis of Oral Squamous Cell Carcinoma.
P2RY13 Exacerbates Intestinal Inflammation by Damaging the Intestinal Mucosal Barrier via Activating IL-6/STAT3 Pathway.
RASAL2 mediated the enhancement of YAP1/TIAM1 signaling promotes malignant phenotypes of pancreatic ductal adenocarcinoma.
Nicotine has no significant cytoprotective activity against SARS-CoV-2 infection.
Aspirin mediates protection from diabetic kidney disease by inducing ferroptosis inhibition.
Cystathionine γ-lyase and hydrogen sulfide modulates glucose transporter Glut1 expression via NF-κB and PI3k/Akt in macrophages during inflammation.
AMBRA1 attenuates the proliferation of uveal melanoma cells.
B16 Membrane-Coated Vesicles for Combined Photodynamic Therapy and Immunotherapy Shift Immune Microenvironment of Melanoma.
Decreased tubulin-binding cofactor B was involved in the formation disorder of nascent astrocyte processes by regulating microtubule plus-end growth through binding with end-binding proteins 1 and 3 after chronic alcohol exposure.
Focused Ultrasound Promotes the Delivery of Gastrodin and Enhances the Protective Effect on Dopaminergic Neurons in a Mouse Model of Parkinson's Disease.
CAMTA1 gene affects the ischemia-reperfusion injury by regulating CCND1.
Predictors of prodromal Parkinson's disease in young adult Pink1-/- rats.
Rapamycin Improved Retinal Function and Morphology in a Mouse Model of Retinal Degeneration.
Laparotomy-Induced Peripheral Inflammation Activates NR2B Receptors on the Brain Mast Cells and Results in Neuroinflammation in a Vagus Nerve-Dependent Manner.
Inhibition of CXCR4 in Spinal Cord and DRG with AMD3100 Attenuates Colon-Bladder Cross-Organ Sensitization.
Keloid Patient Plasma-Derived Exosomal hsa_circ_0020792 Promotes Normal Skin Fibroblasts Proliferation, Migration, and Fibrogenesis via Modulating miR-193a-5p and Activating TGF-β1/Smad2/3 Signaling.
Madecassic Acid Ameliorates the Progression of Osteoarthritis: An in vitro and in vivo Study.
Network Pharmacology and Experimental Verification to Explore the Potential Mechanism of Yin-Huo-Tang for Lung Adenocarcinoma Recurrence.
Sinomenine Inhibits Orthodontic Tooth Movement and Root Resorption in Rats and Enhances Osteogenic Differentiation of PDLSCs.
Exploration of the Effect and Potential Mechanism of Echinacoside Against Endometrial Cancer Based on Network Pharmacology and in vitro Experimental Verification.
Inhibitory effects of luteolin on TLR3-mediated inflammation caused by TAK/NF-κB signaling in human corneal fibroblasts.
Nedd4-2 Haploinsufficiency in Mice Impairs the Ubiquitination of Rer1 and Increases the Susceptibility to Endoplasmic Reticulum Stress and Seizures.
Excitatory and Inhibitory Synaptic Imbalance Caused by Brain-Derived Neurotrophic Factor Deficits During Development in a Valproic Acid Mouse Model of Autism.
The cAMP Response Element- Binding Protein/Brain-Derived Neurotrophic Factor Pathway in Anterior Cingulate Cortex Regulates Neuropathic Pain and Anxiodepression Like Behaviors in Rats.
The Ameliorative Effect of JNK Inhibitor D-JNKI-1 on Neomycin-Induced Apoptosis in HEI-OC1 Cells.
Effect of Tensile Frequency on the Osteogenic Differentiation of Periodontal Ligament Stem Cells.
LPS-Induced Activation of the cGAS-STING Pathway is Regulated by Mitochondrial Dysfunction and Mitochondrial DNA Leakage in Endometritis.
MULT1-Encoding DNA Alleviates Schistosomiasis-Associated Hepatic Fibrosis via Modulating Cellular Immune Response.
TRPV1 and GABA(B1) in the Cerebrospinal Fluid-Contacting Nucleus are Jointly Involved in Chronic Inflammatory Pain in Rats.
The Role of Bone Morphogenetic Protein 4 in Microglial Polarization in the Process of Neuropathic Pain.
MAF bZIP Transcription Factor B (MAFB) Protected Against Ovalbumin-Induced Allergic Rhinitis via the Alleviation of Inflammation by Restoring the T Helper (Th) 1/Th2/Th17 Imbalance and Epithelial Barrier Dysfunction.
Protective Effect of Crocin on Immune Checkpoint Inhibitors-Related Myocarditis Through Inhibiting NLRP3 Mediated Pyroptosis in Cardiomyocytes via NF-κB Pathway.
The Involvement of Endothelin Pathway in Chronic Psychological Stress-Induced Bladder Hyperalgesia Through Capsaicin-Sensitive C-Fiber Afferents.
Galectin-9/Tim-3 pathway mediates dopaminergic neurodegeneration in MPTP-induced mouse model of Parkinson's disease.
Down-regulation of NOTCH1 and PKM2 can inhibit the growth and metastasis of colorectal cancer cells.
Wnt5a protects motor neurons in amyotrophic lateral sclerosis by regulating the Wnt/Ca(2+) signaling pathway.
Senomorphic agent pterostilbene ameliorates osteoarthritis through the PI3K/AKT/NF-κB axis: an in vitro and in vivo study.
Stachydrine hydrochloride ameliorates cardiac hypertrophy through CaMKII/HDAC4/MEF2C signal pathway.
LncRNA PCAT7 promotes non-small cell lung cancer progression by activating miR-486-5p/CDK4 axis-mediated cell cycle.
A novel curcumin oil solution can better alleviate the motor activity defects and neuropathological damage of a Parkinson's disease mouse model.
Huangqin Decoction Exerts Beneficial Effects on Rotenone-Induced Rat Model of Parkinson's Disease by Improving Mitochondrial Dysfunction and Alleviating Metabolic Abnormality of Mitochondria.
Growth Differentiation Factor 15 Regulates Oxidative Stress-Dependent Ferroptosis Post Spinal Cord Injury by Stabilizing the p62-Keap1-Nrf2 Signaling Pathway.
Methyltransferase-Like 3 Rescues the Amyloid-beta protein-Induced Reduction of Activity-Regulated Cytoskeleton Associated Protein Expression via YTHDF1-Dependent N6-Methyladenosine Modification.
Impact prediction of translocation of the mitochondrial outer membrane 70 as biomarker in Alzheimer's disease.
Inducing Synergistic DNA Damage by TRIP13 and PARP1 Inhibitors Provides a Potential Treatment for Hepatocellular Carcinoma.
ASF1b is a novel prognostic predictor associated with cell cycle signaling pathway in gastric cancer.
Targeting HNRNPM Inhibits Cancer Stemness and Enhances Antitumor Immunity in Wnt-activated Hepatocellular Carcinoma.
A Novel Mouse Model Harboring Hepatitis B Virus Covalently Closed Circular DNA.
LHPP suppresses gastric cancer progression via the PI3K/AKT/mTOR signaling pathway.
The lncRNA CRNDE is regulated by E2F6 and sensitizes gastric cancer cells to chemotherapy by inhibiting autophagy.
Down-regulation of MSMO1 promotes the development and progression of pancreatic cancer.
Trichodimerol inhibits inflammation through suppression of the nuclear transcription factor-kappaB/NOD-like receptor thermal protein domain associated protein 3 signaling pathway.
3,3'-diindolylmethane inhibits LPS-induced human chondrocytes apoptosis and extracellular matrix degradation by activating PI3K-Akt-mTOR-mediated autophagy.
No synergistic effect of fecal microbiota transplantation and shugan decoction in water avoidance stress-induced IBS-D rat model.
Qing-Re-Xiao-Zheng-Yi-Qi formula relieves kidney damage and activates mitophagy in diabetic kidney disease.
Bioinformatic analysis of the RNA expression patterns in microgravity-induced bone loss.
Low FNDC5/Irisin expression is associated with aggressive phenotypes in gastric cancer.
MiR-146b-5p/TRAF6 axis is essential for Ginkgo biloba L. extract GBE to attenuate LPS-induced neuroinflammation.
The effects of gut microbiota colonizing on the porcine hypothalamus revealed by whole transcriptome analysis.
MiR-93-5p promotes granulosa cell apoptosis and ferroptosis by the NF-kB signaling pathway in polycystic ovary syndrome.
Astragalus saponins and its main constituents ameliorate ductular reaction and liver fibrosis in a mouse model of DDC-induced cholestatic liver disease.
Identification and validation of P4HB as a novel autophagy-related biomarker in diabetic nephropathy.
Cangfudaotan decoction inhibits mitochondria-dependent apoptosis of granulosa cells in rats with polycystic ovarian syndrome.
Rabbit hemorrhagic disease virus VP60 protein expressed in recombinant swinepox virus self-assembles into virus-like particles with strong immunogenicity in rabbits.
Sanguinarine protects against indomethacin-induced small intestine injury in rats by regulating the Nrf2/NF-κB pathways.
MBD2 mediates Th17 cell differentiation by regulating MINK1 in Th17-dominant asthma.
Structural and functional analysis of the small GTPase ARF1 reveals a pivotal role of its GTP-binding domain in controlling of the generation of viral inclusion bodies and replication of grass carp reovirus.
FGFBP1 as a potential biomarker predicting bacillus Calmette-Guérin response in bladder cancer.
Identification of polyunsaturated fatty acids related key modules and genes in metabolic dysfunction-associated fatty liver disease using WGCNA analysis.
Therapeutic effects and mechanisms of N-(9,10-anthraquinone-2-ylcarbonyl) xanthine oxidase inhibitors on hyperuricemia.
Jiangtang Sanhao formula ameliorates skeletal muscle insulin resistance via regulating GLUT4 translocation in diabetic mice.
The miR-33a-5p/CROT axis mediates ovarian cancer cell behaviors and chemoresistance via the regulation of the TGF-β signal pathway.
Esaxerenone inhibits the macrophage-to-myofibroblast transition through mineralocorticoid receptor/TGF-β1 pathway in mice induced with aldosterone.
Papain-like protease of SARS-CoV-2 inhibits RLR signaling in a deubiquitination-dependent and deubiquitination-independent manner.
A comprehensively prognostic and immunological analysis of actin-related protein 2/3 complex subunit 5 in pan-cancer and identification in hepatocellular carcinoma.
Design, synthesis, and biological characterization of a potent STAT3 degrader for the treatment of gastric cancer.
EST12 regulates Myc expression and enhances anti-mycobacterial inflammatory response via RACK1-JNK-AP1-Myc immune pathway.
A novel CARD11 germline mutation in a Chinese patient of B cell expansion with NF-κB and T cell anergy (BENTA) and literature review.
Qu-Du-San-Jie decoction induces growth inhibition and vascular normalization in NF2-associated vestibular schwannoma.
Stimulatory G-Protein α Subunit Modulates Endothelial Cell Permeability Through Regulation of Plasmalemma Vesicle-Associated Protein.
Mechanism of Tripterygium wilfordii Hook.F.- Trichosanthes kirilowii Maxim decoction in treatment of diabetic kidney disease based on network pharmacology and molecular docking.
Rhein ameliorates transverse aortic constriction-induced cardiac hypertrophy via regulating STAT3 and p38 MAPK signaling pathways.
KangPiLao decoction modulates cognitive and emotional disorders in rats with central fatigue through the GABA/Glu pathway.
TAZ Induces Migration of Microglia and Promotes Neurological Recovery After Spinal Cord Injury.
Integrated pyroptosis measurement and metabolomics to elucidate the effect and mechanism of tangzhiqing on atherosclerosis.
Mycoplasma bovis inhibits autophagy in bovine mammary epithelial cells via a PTEN/PI3K-Akt-mTOR-dependent pathway.
Intestinal Flora-Derived Kynurenic Acid Protects Against Intestinal Damage Caused by Candida albicans Infection via Activation of Aryl Hydrocarbon Receptor.
Effect of Platycodon grandiflorus Polysaccharide on M1 Polarization Induced by Autophagy Degradation of SOCS1/2 Proteins in 3D4/21 Cells.
Identification of a novel cuproptosis-related gene signature and integrative analyses in patients with lower-grade gliomas.
Dihydromyricetin ameliorates osteogenic differentiation of human aortic valve interstitial cells by targeting c-KIT/interleukin-6 signaling pathway.
Ganfule capsule alleviates bile duct ligation-induced liver fibrosis in mice by inhibiting glutamine metabolism.
Comprehensive analyses identify RIPOR2 as a genomic instability-associated immune prognostic biomarker in cervical cancer.
Blockade of Mbd2 by siRNA-loaded liposomes protects mice against OVA-induced allergic airway inflammation via repressing M2 macrophage production.
Retinoic Acid Supplementation Rescues the Social Deficits in Fmr1 Knockout Mice.
Activation of TRPV4 by lactate as a critical mediator of renal fibrosis in spontaneously hypertensive rats after moderate- and high-intensity exercise.
The Proinflammatory Role of Guanylate-Binding Protein 5 in Inflammatory Bowel Diseases.
Transcriptomic Analysis of Dysregulated Genes of the nDNA-mtDNA Axis in a Mouse Model of Dilated Cardiomyopathy.
Icariside Ⅱ Attenuates Palmitic Acid-Induced Endothelial Dysfunction Through SRPK1-Akt-eNOS Signaling Pathway.
Reduced Immunity Regulator MAVS Contributes to Non-Hypertrophic Cardiac Dysfunction by Disturbing Energy Metabolism and Mitochondrial Homeostasis.
Effects and Molecular Regulation Mechanisms of Salinity Stress on the Health and Disease Resistance of Grass Carp.
High expression of ZFP36L2 correlates with the prognosis and immune infiltration in lower-grade glioma.
A Rare Heterozygous TINF2 Deletional Frameshift Mutation in a Chinese Pedigree With a Spectrum of TBDs Phenotypes.
Brevilin A Ameliorates Acute Lung Injury and Inflammation Through Inhibition of NF-κB Signaling via Targeting IKKα/β.
Cyclovirobuxine D Ameliorates Experimental Diabetic Cardiomyopathy by Inhibiting Cardiomyocyte Pyroptosis via NLRP3 in vivo and in vitro.
Toxoplasma gondii CDPK3 Controls the Intracellular Proliferation of Parasites in Macrophages.
Time Series Transcriptomic Analysis by RNA Sequencing Reveals a Key Role of PI3K in Sepsis-Induced Myocardial Injury in Mice.
Hepatocyte-Conditional Knockout of Phosphatidylethanolamine Binding Protein 4 Aggravated LPS/D-GalN-Induced Acute Liver Injury via the TLR4/NF-κB Pathway.
Vincristine Promotes Transdifferentiation of Fibroblasts Into Myofibroblasts via P38 and ERK Signal Pathways.
Csf2ra deletion attenuates acute lung injuries induced by intratracheal inoculation of aerosolized ricin in mice.
Antisense Oligonucleotide-Based Therapy on miR-181a-5p Alleviates Cartilage Degradation of Temporomandibular Joint Osteoarthritis via Promoting SIRT1.
Hydrogen Repairs LPS-Induced Endothelial Progenitor Cells Injury via PI3K/AKT/eNOS Pathway.
CNST is Characteristic of Leukemia Stem Cells and is Associated With Poor Prognosis in AML.
Epigenetic Reader Bromodomain Containing Protein 2 Facilitates Pathological Cardiac Hypertrophy via Regulating the Expression of Citrate Cycle Genes.
Metformin Ameliorates Chronic Colitis-Related Intestinal Fibrosis via Inhibiting TGF-β1/Smad3 Signaling.
Solamargine Inhibits the Development of Hypopharyngeal Squamous Cell Carcinoma by Decreasing LncRNA HOXA11-As Expression.
The Dibenzyl Isoquinoline Alkaloid Berbamine Ameliorates Osteoporosis by Inhibiting Bone Resorption.
Immune Dysfunction Mediated by the ceRNA Regulatory Network in Human Placenta Tissue of Intrahepatic Cholestasis Pregnancy.
Transcriptome Analysis Reveals Key miRNA-mRNA Pathways in Ovarian Tissues of Yunshang Black Goats With Different Kidding Numbers.
Hepatoprotective Effects of Glycyrrhetinic Acid on Lithocholic Acid-Induced Cholestatic Liver Injury Through Choleretic and Anti-Inflammatory Mechanisms.
Obeticholic Acid Induces Hepatoxicity Via FXR in the NAFLD Mice.
Natural Compound ZINC12899676 Reduces Porcine Epidemic Diarrhea Virus Replication by Inhibiting the Viral NTPase Activity.
Myeloid Angiotensin II Type 1 Receptor Mediates Macrophage Polarization and Promotes Vascular Injury in DOCA/Salt Hypertensive Mice.
Targeting Mitochondrial ROS-Mediated Ferroptosis by Quercetin Alleviates High-Fat Diet-Induced Hepatic Lipotoxicity.
The Bradykinin System Contributes to the Regulation of Prostaglandin-Endoperoxide Synthase 2 Expression in Human Amnion Fibroblasts: Implications for Term and Preterm Birth.
Astragaloside IV Alleviates Intestinal Barrier Dysfunction via the AKT-GSK3β-β-Catenin Pathway in Peritoneal Dialysis.
Neutrophil Extracellular Traps (NETs) Promote Non-Small Cell Lung Cancer Metastasis by Suppressing lncRNA MIR503HG to Activate the NF-κB/NLRP3 Inflammasome Pathway.
A Novel STAT3 Gain-of-Function Mutation in Fatal Infancy-Onset Interstitial Lung Disease.
Maresin1 Protect Against Ferroptosis-Induced Liver Injury Through ROS Inhibition and Nrf2/HO-1/GPX4 Activation.
Scorias spongiosa Polysaccharides Promote the Antioxidant and Anti-Inflammatory Capacity and Its Effect on Intestinal Microbiota in Mice.
Glucocorticoid induced group 2 innate lymphoid cell overactivation exacerbates experimental colitis.
Polydatin Glycosides Improve Monocrotaline-Induced Pulmonary Hypertension Injury by Inhibiting Endothelial-To-Mesenchymal Transition.
Theaflavin-3,3'-Digallate from Black Tea Inhibits Neointima Formation Through Suppression of the PDGFRβ Pathway in Vascular Smooth Muscle Cells.
Rosmarinic Acid Ameliorates Pulmonary Ischemia/Reperfusion Injury by Activating the PI3K/Akt Signaling Pathway.
S100P promotes trophoblast syncytialization during early placenta development by regulating YAP1.
Analysis of Interaction Network Between Host Protein and M Protein of Swine Acute Diarrhea Syndrome Coronavirus.
YTHDF1 Negatively Regulates Treponema pallidum-Induced Inflammation in THP-1 Macrophages by Promoting SOCS3 Translation in an m6A-Dependent Manner.
Single Cell Dissection of Epithelial-Immune Cellular Interplay in Acute Kidney Injury Microenvironment.
Construction of a Novel LncRNA Signature Related to Genomic Instability to Predict the Prognosis and Immune Activity of Patients With Hepatocellular Carcinoma.
Continuous Activation of Dopamine Receptors Alleviates LPS-Induced Liver Injury in Mice via β-arrestin2 Dependent Akt/NF-κB Pathway.
LncRNA NEAT1 Potentiates SREBP2 Activity to Promote Inflammatory Macrophage Activation and Limit Hantaan Virus Propagation.
KIFC3 Promotes Proliferation, Migration, and Invasion in Colorectal Cancer via PI3K/AKT/mTOR Signaling Pathway.
Super-Enhancer-Associated Long Non-Coding RNA LINC01485 Promotes Osteogenic Differentiation of Human Bone Marrow Mesenchymal Stem Cells by Regulating MiR-619-5p/RUNX2 Axis.
ASF1B is a Promising Prognostic Biomarker and Correlates With Immunotherapy Efficacy in Hepatocellular Carcinoma.
Restoring Impaired Fertility Through Diet: Observations of Switching From High-Fat Diet During Puberty to Normal Diet in Adulthood Among Obese Male Mice.
IL25 Enhanced Colitis-Associated Tumorigenesis in Mice by Upregulating Transcription Factor GLI1.
Multiple SARS-CoV-2 Variants Exhibit Variable Target Cell Infectivity and Ability to Evade Antibody Neutralization.
Matrix Remodeling-Associated Protein 8 as a Novel Indicator Contributing to Glioma Immune Response by Regulating Ferroptosis.
The Effect of Blood Flow-Restricted Low Resistance Training on Microvascular Circulation of Myocardium in Spontaneously Hypertensive Rats.
The Role of RAB GTPases and Its Potential in Predicting Immunotherapy Response and Prognosis in Colorectal Cancer.
Identification of a De Novo Heterozygous Missense ACTB Variant in Baraitser-Winter Cerebrofrontofacial Syndrome.
Sirtuin 2 Alleviates Chronic Neuropathic Pain by Suppressing Ferroptosis in Rats.
Induction of Collagen I by CXCL10 in Ovarian Theca-Stroma Cells via the JNK Pathway.
NUSAP1 Could be a Potential Target for Preventing NAFLD Progression to Liver Cancer.
Estradiol Ameliorates Acute Kidney Ischemia-Reperfusion Injury by Inhibiting the TGF-βRI-SMAD Pathway.
Simvastatin Downregulates the SARS-CoV-2-Induced Inflammatory Response and Impairs Viral Infection Through Disruption of Lipid Rafts.
Punicalagin Alleviates Psoriasis by Inhibiting NF-κB-Mediated IL-1β Transcription and Caspase-1-Regulated IL-1β Secretion.
Miya Improves Osteoarthritis Characteristics via the Gut-Muscle-Joint Axis According to Multi-Omics Analyses.
Celastrol Alleviates Autoimmune Hepatitis Through the PI3K/AKT Signaling Pathway Based on Network Pharmacology and Experiments.
Berberine Improves Vascular Dysfunction by Inhibiting Trimethylamine-N-oxide via Regulating the Gut Microbiota in Angiotensin II-Induced Hypertensive Mice.
Sodium Butyrate Attenuates Taurocholate-Induced Acute Pancreatitis by Maintaining Colonic Barrier and Regulating Gut Microorganisms in Mice.
Scalable Dual-Fluorescence Assay for Functional Interpretation of HNF-4α Missense Variants.
Interleukin-25-Mediated-IL-17RB Upregulation Promotes Cutaneous Wound Healing in Diabetic Mice by Improving Endothelial Cell Functions.
Naoluo Xintong Decoction in the Treatment of Ischemic Stroke: A Network Analysis of the Mechanism of Action.
An Herbal Product Alleviates Bleomycin-Induced Pulmonary Fibrosis in Mice via Regulating NF-κB/TNF-α Signaling in Macrophages.
Tormentic Acid Ameliorates Hepatic Fibrosis in vivo by Inhibiting Glycerophospholipids Metabolism and PI3K/Akt/mTOR and NF-κB Pathways: Based on Transcriptomics and Metabolomics.
Deferoxamine Alleviates Osteoarthritis by Inhibiting Chondrocyte Ferroptosis and Activating the Nrf2 Pathway.
Androgen Excess Induced Mitochondrial Abnormality in Ovarian Granulosa Cells in a Rat Model of Polycystic Ovary Syndrome.
Comprehensive Analysis of LncRNA AC010789.1 Delays Androgenic Alopecia Progression by Targeting MicroRNA-21 and the Wnt/β-Catenin Signaling Pathway in Hair Follicle Stem Cells.
Thymopentin-Mediated Inhibition of Cancer Stem Cell Stemness Enhances the Cytotoxic Effect of Oxaliplatin on Colon Cancer Cells.
Delivery of Basic Fibroblast Growth Factor Through an In Situ Forming Smart Hydrogel Activates Autophagy in Schwann Cells and Improves Facial Nerves Generation via the PAK-1 Signaling Pathway.
Aberrant Expression of ADARB1 Facilitates Temozolomide Chemoresistance and Immune Infiltration in Glioblastoma.
Deficiency of RARα Suppresses Decidualization via Downregulating CEBPB Transcription in Women With Recurrent Implantation Failure.
TREM2 is associated with tumor immunity and implies poor prognosis in glioma.
Creatine modulates cellular energy metabolism and protects against cancer cachexia-associated muscle wasting.
Long non-coding RNA SNHG9 regulates viral replication in rhabdomyosarcoma cells infected with enterovirus D68 via miR-150-5p/c-Fos axis.
Arbitrary Ca(2+) regulation for endothelial nitric oxide, NFAT and NF-κB activities by an optogenetic approach.
Overnutrition-induced gout: An immune response to NLRP3 inflammasome dysregulation by XOD activity increased in quail.
Oroxin B alleviates osteoarthritis through anti-inflammation and inhibition of PI3K/AKT/mTOR signaling pathway and enhancement of autophagy.
Novel insight of N(6)-methyladenosine modified subtypes in abdominal aortic aneurysm.
AIM2 inflammasome activation benefits the therapeutic effect of BCG in bladder carcinoma.
Protective effects of mefunidone on ischemia-reperfusion injury/Folic acid-induced acute kidney injury.
Regulation of Yujin Powder alcoholic extracts on ILC3s-TD IgA-colonic mucosal flora axis of DSS-induced ulcerative colitis.
Malvidin alleviates mitochondrial dysfunction and ROS accumulation through activating AMPK-α/UCP2 axis, thereby resisting inflammation and apoptosis in SAE mice.
Potential cardiotoxicity induced by Euodiae Fructus: In vivo and in vitro experiments and untargeted metabolomics research.
Ginkgolide C slows the progression of osteoarthritis by activating Nrf2/HO-1 and blocking the NF-κB pathway.
Crosstalk of necroptosis and pyroptosis defines tumor microenvironment characterization and predicts prognosis in clear cell renal carcinoma.
Lipidomics reveals the potential mechanism of honokiol against adenine-induced chronic kidney disease.
Quantification of promoting efficiency and reducing toxicity of Traditional Chinese Medicine: A case study of the combination of Tripterygium wilfordii hook. f. and Lysimachia christinae hance in the treatment of lung cancer.
Immunostimulatory activity and structure-activity relationship of epimedin B from Epimedium brevicornu Maxim.
X-box binding protein 1: A new metabolic mediator and drug target of metformin?
Melatonin inhibits HCC progression through regulating the alternative splicing of NEMO.
African swine fever virus infection activates inflammatory responses through downregulation of the anti-inflammatory molecule C1QTNF3.
METTL3/m(6)A/IFIT2 regulates proliferation, invasion and immunity in esophageal squamous cell carcinoma.
Prrx1 promotes resistance to temozolomide by upregulating ABCC1 and inducing vasculogenic mimicry in glioma.
MYBL2 accelerates epithelial-mesenchymal transition and hepatoblastoma metastasis via the Smad/SNAI1 pathway.
Decreased RNA m(6)A methylation enhances the process of the epithelial mesenchymal transition and vasculogenic mimicry in glioblastoma.
5-aza-2'-deoxycytidine potentiates anti-tumor immunity in colorectal peritoneal metastasis by modulating ABC A9-mediated cholesterol accumulation in macrophages.
Nintedanib enhances the efficacy of PD-L1 blockade by upregulating MHC-I and PD-L1 expression in tumor cells.
circHIPK3 prevents cardiac senescence by acting as a scaffold to recruit ubiquitin ligase to degrade HuR.
The PROTAC selectively degrading Bcl-x(L) represents a novel Hedgehog pathway inhibitor with capacity of combating resistance to Smoothened inhibitors while sparing bone growth.
Hippocalcin-Like 1 blunts liver lipid metabolism to suppress tumorigenesis via directly targeting RUVBL1-mTOR signaling.
Ninj2 regulates Schwann cells development by interfering laminin-integrin signaling.
Yap1 modulates cardiomyocyte hypertrophy via impaired mitochondrial biogenesis in response to chronic mechanical stress overload.
UBR5 promotes tumor immune evasion through enhancing IFN-γ-induced PDL1 transcription in triple negative breast cancer.
Multi-omics analysis of kinesin family member 2C in human tumors: novel prognostic biomarker and tumor microenvironment regulator.
Deglycosylation of SLAMF7 in breast cancers enhances phagocytosis.
Blockade of phosphotyrosine pathways suggesting SH2 superbinder as a novel therapy for pulmonary fibrosis.
Consequences of somatic mutations of GIRK1 detected in primary malign tumors on expression and function of G-protein activated, inwardly rectifying, K(+) channels.
Parthenolide and arsenic trioxide co-trigger autophagy-accompanied apoptosis in hepatocellular carcinoma cells.
INPP4B inhibits glioma cell proliferation and immune escape via inhibition of the PI3K/AKT signaling pathway.
Phosphoproteomics reveals that cinobufotalin promotes intrahepatic cholangiocarcinoma cell apoptosis by activating the ATM/CHK2/p53 signaling pathway.
Irradiation enhances the malignancy-promoting behaviors of cancer-associated fibroblasts.
BI 2536 induces gasdermin E-dependent pyroptosis in ovarian cancer.
Identification of necroptosis-related genes for predicting prognosis and exploring immune infiltration landscape in colon adenocarcinoma.
The Novel LncRNA WASH5P Inhibits Colorectal Cancer Carcinogenesis via Targeting AKT Signaling Pathway.
Knockdown of USP8 inhibits prostate cancer cell growth, proliferation, and metastasis and promotes docetaxel's activity by suppressing the NF-kB signaling pathway.
High Levels of DEAH-Box Helicases Relate to Poor Prognosis and Reduction of DHX9 Improves Radiosensitivity of Hepatocellular Carcinoma.
SEMA3C Supports Pancreatic Cancer Progression by Regulating the Autophagy Process and Tumor Immune Microenvironment.
ELOVLs Predict Distinct Prognosis Value and Immunotherapy Efficacy In Patients With Hepatocellular Carcinoma.
SETD3 Methyltransferase Regulates PLK1 Expression to Promote In Situ Hepatic Carcinogenesis.
MOF negatively regulates estrogen receptor α signaling via CUL4B-mediated protein degradation in breast cancer.
Mitochondrion-Localized SND1 Promotes Mitophagy and Liver Cancer Progression Through PGAM5.
Campylobacter jejuni Cytolethal Distending Toxin Induces GSDME-Dependent Pyroptosis in Colonic Epithelial Cells.
Vasoactive intestinal peptide-VIPR2 signaling regulates tumor cell migration.
The CK1δ/ϵ-Tip60 Axis Enhances Wnt/β-Catenin Signaling via Regulating β-Catenin Acetylation in Colon Cancer.
MSLN Correlates With Immune Infiltration and Chemoresistance as a Prognostic Biomarker in Ovarian Cancer.
Inhibition of Angiogenesis and Extracellular Matrix Remodeling: Synergistic Effect of Renin-Angiotensin System Inhibitors and Bevacizumab.
Exosomal lncRNA LINC01356 Derived From Brain Metastatic Nonsmall-Cell Lung Cancer Cells Remodels the Blood-Brain Barrier.
ACADL Functions as a Tumor Suppressor in Hepatocellular Carcinoma Metastasis by Inhibiting Matrix Metalloproteinase 14.
Olaparib Induces RPL5/RPL11-Dependent p53 Activation via Nucleolar Stress.
LncRNA PELATON, a Ferroptosis Suppressor and Prognositic Signature for GBM.
FUS-DDIT3 Fusion Oncoprotein Expression Affects JAK-STAT Signaling in Myxoid Liposarcoma.
TGF-β1-Mediated PD-L1 Glycosylation Contributes to Immune Escape via c-Jun/STT3A Pathway in Nasopharyngeal Carcinoma.
Identification of CFHR4 associated with poor prognosis of hepatocellular carcinoma.
Lactobacillus rhamnosus GR-1 Alleviates Escherichia coli-Induced Inflammation via NF-κB and MAPKs Signaling in Bovine Endometrial Epithelial Cells.
SRSF3 Expression Serves as a Potential Biomarker for Prognostic and Immune Response in Pan-Cancer.
RPS3 Promotes the Metastasis and Cisplatin Resistance of Adenoid Cystic Carcinoma.
Low Level of PALMD Contributes to the Metastasis of Uveal Melanoma.
Thymidine Kinase 1 Drives Skin Cutaneous Melanoma Malignant Progression and Metabolic Reprogramming.
Identification of LncRNA Prognostic Signature Associated With Genomic Instability in Pancreatic Adenocarcinoma.
Comprehensive Analysis of the PRDXs Family in Head and Neck Squamous Cell Carcinoma.
Phase II Study of Gemcitabine, Peg-Asparaginase, Dexamethasone and Methotrexate Regimen for Newly Diagnosed Extranodal Natural Killer/T-Cell Lymphoma, Nasal Type: Final Analysis With Long-Term Follow-Up and Rational Research for the Combination.
Distinct Roles of m(5)C RNA Methyltransferase NSUN2 in Major Gynecologic Cancers.
CDC27-ODC1 Axis Promotes Metastasis, Accelerates Ferroptosis and Predicts Poor Prognosis in Neuroblastoma.
ASB17 Facilitates the Burst of LPS-Induced Inflammation Through Maintaining TRAF6 Stability.
N-Glycosylation at Asn291 Stabilizes TIM-4 and Promotes the Metastasis of NSCLC.
HRK inhibits colorectal cancer cells proliferation by suppressing the PI3K/AKT/mTOR pathway.
IGF2BP3 promotes progression of gallbladder carcinoma by stabilizing KLK5 mRNA in N(6)-methyladenosine-dependent binding.
Weighted gene co-expression network reveals driver genes contributing to phenotypes of anaplastic thyroid carcinoma and immune checkpoint identification for therapeutic targets.
CXCL10-armed oncolytic adenovirus promotes tumor-infiltrating T-cell chemotaxis to enhance anti-PD-1 therapy.
MerTK-mediated efferocytosis promotes immune tolerance and tumor progression in osteosarcoma through enhancing M2 polarization and PD-L1 expression.
Control of fibrosis and hypertrophic scar formation via glycolysis regulation with IR780.
M1 macrophage-derived extracellular vesicle containing tsRNA-5006c promotes osteogenic differentiation of aortic valve interstitial cells through regulating mitophagy.
Ac2-26 attenuates hepatic ischemia-reperfusion injury in mice via regulating IL-22/IL-22R1/STAT3 signaling.
SERBP1 affects the apoptotic level by regulating the expression and alternative splicing of cellular and metabolic process genes in HeLa cells.
Identification and validation of immune related core transcription factors GTF2I in NAFLD.
Ferroptotic cardiomyocyte-derived exosomes promote cardiac macrophage M1 polarization during myocardial infarction.
WASH regulates the oxidative stress Nrf2/ARE pathway to inhibit proliferation and promote apoptosis of HeLa cells under the action of Jolkinolide B.
Transcriptome changes in ERGIC3-knockdown hepatocellular carcinoma cells: ERGIC3 is a novel immune function related gene.
Glucocorticoids induce osteonecrosis of the femoral head in rats via PI3K/AKT/FOXO1 signaling pathway.
A long noncoding RNA GTF2IRD2P1 suppresses cell proliferation in bladder cancer by inhibiting the Wnt/β‑catenin signaling pathway.
Protection of catalpol against triptolide-induced hepatotoxicity by inhibiting excessive autophagy via the PERK-ATF4-CHOP pathway.
Targeting EIF3C to suppress the development and progression of nasopharyngeal carcinoma.
P14AS upregulates gene expression in the CDKN2A/2B locus through competitive binding to PcG protein CBX7.
The SNARE protein Vti1b is recruited to the sites of BCR activation but is redundant for antigen internalisation, processing and presentation.
Rictor maintains endothelial integrity under shear stress.
The proneural transcription factor ASCL1 regulates cell proliferation and primes for differentiation in neuroblastoma.
Upregulated ENC1 predicts unfavorable prognosis and correlates with immune infiltration in endometrial cancer.
Primary Repair for Treating Acute Proximal Anterior Cruciate Ligament Tears: A Histological Analysis and Prospective Clinical Trial.
ARPC2: A Pan-Cancer Prognostic and Immunological Biomarker That Promotes Hepatocellular Carcinoma Cell Proliferation and Invasion.
Gender Differential Expression of AR/miR-21 Signaling Axis and Its Protective Effect on Renal Ischemia-Reperfusion Injury.
CRISPR-Cas13-Mediated Knockdown of Regulator of G-Protein Signaling 8 (RGS8) Does Not Affect Purkinje Cell Dendritic Development.
Deacetylation of YAP1 Promotes the Resistance to Chemo- and Targeted Therapy in FLT3-ITD(+) AML Cells.
HSPA6 is Correlated With the Malignant Progression and Immune Microenvironment of Gliomas.
Differential Degradation of TRA2A and PYCR2 Mediated by Ubiquitin E3 Ligase E4B.
Theaflavin Attenuates TBHP-Induced Endothelial Cells Oxidative Stress by Activating PI3K/AKT/Nrf2 and Accelerates Wound Healing in Rats.
Hesperidin Ameliorates Dexamethasone-Induced Osteoporosis by Inhibiting p53.
ITGAL as a Prognostic Biomarker Correlated With Immune Infiltrates in Gastric Cancer.
Biomimetic Metal-Organic Framework Nanoparticles for Synergistic Combining of SDT-Chemotherapy Induce Pyroptosis in Gastric Cancer.
Hyaluronic Acid Facilitates Angiogenesis of Endothelial Colony Forming Cell Combining With Mesenchymal Stem Cell via CD44/ MicroRNA-139-5p Pathway.
Endoplasmic Reticulum Stress Is Involved in Muscular Pathogenesis in Idiopathic Inflammatory Myopathies.
Development of Tumor Mutation Burden-Related Prognostic Model and Novel Biomarker Identification in Stomach Adenocarcinoma.
H19 Promotes Osteoblastic Transition by Acting as ceRNA of miR-140-5p in Vascular Smooth Muscle Cells.
Chitosan degradation products promote healing of burn wounds of rat skin.
Metformin carbon nanodots promote odontoblastic differentiation of dental pulp stem cells by pathway of autophagy.
PKC signal amplification suppresses non-small cell lung cancer growth by promoting p21 expression and phosphorylation.
An EPO-loaded multifunctional hydrogel synergizing with adipose-derived stem cells restores neurogenic erectile function via enhancing nerve regeneration and penile rehabilitation.
HSPA5 repressed ferroptosis to promote colorectal cancer development by maintaining GPX4 stability.
lncKRT16P6 promotes tongue squamous cell carcinoma progression by sponging miR‑3180 and regulating GATAD2A expression.
Cerebral small vessel disease caused by PLOD3 mutation: Expanding the phenotypic spectrum of lysyl hydroxylase-3 deficiency.
Inhibitory effects of cedar pine needle extract on H9N2 avian influenza virus in vitro and in vivo.
The caspase-1 inhibitor VX765 upregulates connexin 43 expression and improves cell-cell communication after myocardial infarction via suppressing the IL-1β/p38 MAPK pathway.
Patchouli alcohol as a selective estrogen receptor β agonist ameliorates AD-like pathology of APP/PS1 model mice.
FumDSB can alleviate the inflammatory response induced by fumonisin B(1) in growing pigs.
YAP knockdown in combination with ferroptosis induction increases the sensitivity of HOS human osteosarcoma cells to pyropheophorbide-α methyl ester-mediated photodynamic therapy.
Small extracellular vesicles derived from PD-L1-modified mesenchymal stem cell promote Tregs differentiation and prolong allograft survival.
Fine Particulate Matter Triggers α-Synuclein Fibrillization and Parkinson-like Neurodegeneration.
FUS aggregation following ischemic stroke favors brain astrocyte activation through inducing excessive autophagy.
TMEM97 is transcriptionally activated by YY1 and promotes colorectal cancer progression via the GSK-3β/β-catenin signaling pathway.
RhoGDI1 interacts with PHLDA2, suppresses the proliferation, migration, and invasion of trophoblast cells, and participates in the pathogenesis of preeclampsia.
Glutamate drives 'local Ca(2+) release' in cardiac pacemaker cells.
G protein-coupled receptor kinase phosphorylation of distal C-tail sites specifies βarrestin1-mediated signaling by chemokine receptor CXCR4.
Progranulin-derived granulin E and lysosome membrane protein CD68 interact to reciprocally regulate their protein homeostasis.
Induction of zinc finger protein RNF6 auto-ubiquitination for the treatment of myeloma and chronic myeloid leukemia.
Inhibition of cGAS-STING by JQ1 alleviates oxidative stress-induced retina inflammation and degeneration.
Valosin-containing protein (VCP/p97) is responsible for the endocytotic trafficking of classical swine fever virus.
Circulating cell-free mtDNA release is associated with the activation of cGAS-STING pathway and inflammation in mitochondrial diseases.
Rare variants in GABRG2 associated with sleep-related hypermotor epilepsy.
Rare pathogenic variants in WNK3 cause X-linked intellectual disability.
Sevoflurane exposure during the second trimester induces neurotoxicity in offspring rats by hyperactivation of PARP-1.
CircFAT1 regulates retinal pigment epithelial cell pyroptosis and autophagy via mediating m6A reader protein YTHDF2 expression in diabetic retinopathy.
Chronological attenuation of NPRA/PKG/AMPK signaling promotes vascular aging and elevates blood pressure.
MiR-200b-3p is upregulated in the placental tissues from patients with preeclampsia and promotes the development of preeclampsia via targeting profilin 2.
MYC as a therapeutic target for the treatment of triple-negative breast cancer: preclinical investigations with the novel MYC inhibitor, MYCi975.
Type I collagen reduces lipid accumulation during adipogenesis of preadipocytes 3T3-L1 via the YAP-mTOR-autophagy axis.
HAP1 interacts with 14-3-3 to regulate epileptic seizure via GABA(A)R-mediated inhibitory synaptic transmission in pentylenetetrazole rat model.
Outer membrane vesicles derived from heatstroke-associated intestinal microbiota promote multiple organ injury in mice.
MicroRNA-223 downregulation promotes HBx-induced podocyte pyroptosis by targeting the NLRP3 inflammasome.
CHRNA1 induces sarcopenia through neuromuscular synaptic elimination.
Colchicine improves severe acute pancreatitis-induced acute lung injury by suppressing inflammation, apoptosis and oxidative stress in rats.
Allantoin ameliorates amyloid β-peptide-induced memory impairment by regulating the PI3K/Akt/GSK-3β signaling pathway in rats.
Hypouricemic effect of 2,4-dihydroxybenzoic acid methyl ester in hyperuricemic mice through inhibiting XOD and down-regulating URAT1.
ATF4 protects against sorafenib-induced cardiotoxicity by suppressing ferroptosis.
Injectable cartilage matrix hydrogel loaded with cartilage endplate stem cells engineered to release exosomes for non-invasive treatment of intervertebral disc degeneration.
Neutrophil extracellular traps induced by Porphyromonas gingivalis lipopolysaccharide modulate inflammatory responses via a Ca(2+)-dependent pathway.
Compromised glycolysis contributes to foot process fusion of podocytes in diabetic kidney disease: Role of ornithine catabolism.
TMEM92 acts as an immune-resistance and prognostic marker in pancreatic cancer from the perspective of predictive, preventive, and personalized medicine.
Identifying potential signatures for atherosclerosis in the context of predictive, preventive, and personalized medicine using integrative bioinformatics approaches and machine-learning strategies.
Design, semi-synthesis and bioactivity evaluation of novel podophyllotoxin derivatives as potent anti-tumor agents.
SGLT2 inhibitor, canagliflozin, ameliorates cardiac inflammation in experimental autoimmune myocarditis.
Angiotensin II type 2 receptor pharmacological agonist, C21, reduces the inflammation and pain hypersensitivity in mice with joint inflammatory pain.
PTS is activated by ATF4 and promotes lung adenocarcinoma development via the Wnt pathway.
Kynurenine metabolism is altered in mdx mice: a potential muscle to brain connection.
ΔNp63α mediates sulforaphane suppressed colorectal cancer stem cell properties through transcriptional regulation of Nanog/Oct4/Sox2.
Targeting p65 to inhibit Cas3 transcription by Onjisaponin B for radiation damage therapy in p65+/- mice.
Huoxin pill prevents excessive inflammation and cardiac dysfunction following myocardial infarction by inhibiting adverse Wnt/β‑catenin signaling activation.
Tetrahydrocurcumin improves lipopolysaccharide-induced myocardial dysfunction by inhibiting oxidative stress and inflammation via JNK/ERK signaling pathway regulation.
Celastrol upregulated ATG7 triggers autophagy via targeting Nur77 in colorectal cancer.
Enhancer of zeste homolog 2 exerts functions in gastric cancer development via modulating microRNA-222-3p methylation and WEE1 expression.
Mannose inhibits the growth of prostate cancer through a mitochondrial mechanism.
Human TRUB1 is a highly conserved pseudouridine synthase responsible for the formation of Ψ55 in mitochondrial tRNAAsn, tRNAGln, tRNAGlu and tRNAPro.
N4-acetylcytidine regulates the replication and pathogenicity of enterovirus 71.
Lactobacillus rhamnosus GR-1 attenuates foodborne Bacillus cereus-induced NLRP3 inflammasome activity in bovine mammary epithelial cells by protecting intercellular tight junctions.
Lactobacillusjohnsonii L531 Protects against Salmonella Infantis-Induced Intestinal Damage by Regulating the NOD Activation, Endoplasmic Reticulum Stress, and Autophagy.
THZ1 targeting CDK7 suppresses c-KIT transcriptional activity in gastrointestinal stromal tumours.
Targeting Therapeutic Resistance and Multinucleate Giant Cells in CCNE1-Amplified HR-Proficient Ovarian Cancer.
Mitochondrial outer membrane protein FUNDC2 promotes ferroptosis and contributes to doxorubicin-induced cardiomyopathy.
CPEB2 m6A methylation regulates blood-tumor barrier permeability by regulating splicing factor SRSF5 stability.
Pou3f1 mediates the effect of Nfatc3 on ulcerative colitis-associated colorectal cancer by regulating inflammation.
LINC00839 promotes colorectal cancer progression by recruiting RUVBL1/Tip60 complexes to activate NRF1.
Lysosomal K(+) channel TMEM175 promotes apoptosis and aggravates symptoms of Parkinson's disease.
Knockdown of FOXA1 enhances the osteogenic differentiation of human bone marrow mesenchymal stem cells partly via activation of the ERK1/2 signalling pathway.
Hsa_circ_0001485 promoted osteogenic differentiation by targeting BMPR2 to activate the TGFβ-BMP pathway.
Prinsepiae Nux Extract Activates NRF2 Activity and Protects UVB-Induced Damage in Keratinocyte.
miR-124 regulates early isolation-induced social abnormalities via inhibiting myelinogenesis in the medial prefrontal cortex.
Low Expression of Mitofusin 1 Gene Leads to Mitochondrial Dysfunction and Embryonic Genome Activation Failure in Ovine-Bovine Inter-Species Cloned Embryos.
Oxalate induces the ossification of RTECs by activating the JAK2/STAT3 signaling pathway and participates in the formation of kidney stones.
Palmitic acid promotes endothelial-to-mesenchymal transition via activation of the cytosolic DNA-sensing cGAS-STING pathway.
Supramolecular Hydrogel-Wrapped Gingival Mesenchymal Stem Cells in Cutaneous Radiation Injury.
WTAP promotes oesophageal squamous cell carcinoma development by decreasing CPSF4 expression in an m(6)A-dependent manner.
Moxidectin induces autophagy arrest in colorectal cancer.
The AHNAK induces increased IL-6 production in CD4+ T cells and serves as a potential diagnostic biomarker for recurrent pregnancy loss.
Thyroid Hormone Induces Oral Cancer Growth via the PD-L1-Dependent Signaling Pathway.
HIV-1 Preintegration Complex Preferentially Integrates the Viral DNA into Nucleosomes Containing Trimethylated Histone 3-Lysine 36 Modification and Flanking Linker DNA.
ACLP promotes activation of cancer-associated fibroblasts and tumor metastasis via ACLP-PPARγ-ACLP feedback loop in pancreatic cancer.
METTL3 suppresses anlotinib sensitivity by regulating m(6)A modification of FGFR3 in oral squamous cell carcinoma.
ABAT gene expression associated with the sensitivity of hypomethylating agents in myelodysplastic syndrome through CXCR4/mTOR signaling.
Dexmedetomidine prevents hemorrhagic brain injury by reducing damage induced by ferroptosis in mice.
Expression profiles of microRNAs in midbrain of MPTP-treated mice determined by microRNA sequencing.
β-Klotho Promotes the Development of Intrauterine Adhesions via the PI3K/AKT Signaling Pathway.
2-Deoxy-D-glucose Alleviates Cancer Cachexia-Induced Muscle Wasting by Enhancing Ketone Metabolism and Inhibiting the Cori Cycle.
Antiviral Drugs Screening for Swine Acute Diarrhea Syndrome Coronavirus.
Exosomal AP000439.2 from clear cell renal cell carcinoma induces M2 macrophage polarization to promote tumor progression through activation of STAT3.
PKM2 promotes pulmonary fibrosis by stabilizing TGF-β1 receptor I and enhancing TGF-β1 signaling.
IDH1 Promotes Foam Cell Formation by Aggravating Macrophage Ferroptosis.
Statin shapes inflamed tumor microenvironment and enhances immune checkpoint blockade in non-small cell lung cancer.
FTH1- and SAT1-Induced Astrocytic Ferroptosis Is Involved in Alzheimer's Disease: Evidence from Single-Cell Transcriptomic Analysis.
Activation of oxytocin receptors in mouse GABAergic amacrine cells modulates retinal dopaminergic signaling.
Elevated ganglioside GM2 activator (GM2A) in human brain tissue reduces neurite integrity and spontaneous neuronal activity.
Silencing circFTO inhibits malignant phenotype through modulating DUSP4 expression in clear cell renal cell carcinoma.
A new K(+)channel-independent mechanism is involved in the antioxidant effect of XE-991 in an in vitro model of glucose metabolism impairment: implications for Alzheimer's disease.
The Novel Protein ADAMTS16 Promotes Gastric Carcinogenesis by Targeting IFI27 through the NF-κb Signaling Pathway.
Hnrnpk maintains chondrocytes survival and function during growth plate development via regulating Hif1α-glycolysis axis.
MED16 Promotes Tumour Progression and Tamoxifen Sensitivity by Modulating Autophagy through the mTOR Signalling Pathway in ER-Positive Breast Cancer.
Tissue-restricted inhibition of mTOR using chemical genetics.
Strategies for understanding the role of cellular heterogeneity in the pathogenesis of lung cancer: a cell model for chronic exposure to cigarette smoke extract.
Proteomics and Biochemical Analyses of Secreted Proteins Revealed a Novel Mechanism by Which ADAM12S Regulates the Migration of Gastric Cancer Cells.
Micropeptide MIAC inhibits the tumor progression by interacting with AQP2 and inhibiting EREG/EGFR signaling in renal cell carcinoma.
Cell adhesion molecule BVES functions as a suppressor of tumor cells extrusion in hepatocellular carcinoma metastasis.
TWIST1 induces proteasomal degradation of β-catenin during the differentiation of ovarian cancer stem-like cells.
Biomimetic Red Blood Cell Membrane-Mediated Nanodrugs Loading Ursolic Acid for Targeting NSCLC Therapy.
CAV2 promotes the invasion and metastasis of head and neck squamous cell carcinomas by regulating S100 proteins.
CTCF DNA-binding domain undergoes dynamic and selective protein-protein interactions.
Confined migration induces heterochromatin formation and alters chromatin accessibility.
TMUB1 is an endoplasmic reticulum-resident escortase that promotes the p97-mediated extraction of membrane proteins for degradation.
An integrated study of Shenling Baizhu San against hyperuricemia: Efficacy evaluation, core target identification and active component discovery.
Th17/Treg imbalance mediates hepatic intolerance to exogenous lipopolysaccharide and exacerbates liver injury in triptolide induced excessive immune response.
Yangjing Zhongyu decoction facilitates mitochondrial activity, estrogenesis, and energy metabolism in H(2)O(2)-induced human granulosa cell line KGN.
Aberrant human ClpP activation disturbs mitochondrial proteome homeostasis to suppress pancreatic ductal adenocarcinoma.
Blockage of the IDO1 pathway by charge-switchable nanoparticles amplifies immunogenic cell death for enhanced cancer immunotherapy.
Small-molecule eRF3a degraders rescue CFTR nonsense mutations by promoting premature termination codon readthrough.
Blockage of Orai1-Nucleolin interaction meditated calcium influx attenuates breast cancer cells growth.
Adaptive Mutation in the Main Protease Cleavage Site of Feline Coronavirus Renders the Virus More Resistant to Main Protease Inhibitors.
Differential Protective Effect of Resveratrol and Its Microbial Metabolites on Intestinal Barrier Dysfunction is Mediated by the AMPK Pathway.
The interaction between autophagy and the epithelial-mesenchymal transition mediated by NICD/ULK1 is involved in the formation of diabetic cataracts.
Upregulation of miR-520c-3p via hepatitis B virus drives hepatocellular migration and invasion by the PTEN/AKT/NF-κB axis.
A covalent inhibitor of K-Ras(G12C) induces MHC class I presentation of haptenated peptide neoepitopes targetable by immunotherapy.
GCAF(TMEM251) regulates lysosome biogenesis by activating the mannose-6-phosphate pathway.
Hypoxia-induced polarization of M2 macrophages and C-C motif chemokine ligand 5 secretion promotes the migration and invasion of trophoblasts†.
A novel homozygous mutation in the PADI6 gene causes early embryo arrest.
Transient Receptor Potential Vanilloid Type 1 Protects Against Pressure Overload-Induced Cardiac Hypertrophy by Promoting Mitochondria-Associated Endoplasmic Reticulum Membranes.
BCAP31 is involved in modulating colorectal cancer cell proliferation via the Emerin/β-catenin axis.
A20 inhibits periodontal bone resorption and NLRP3-mediated M1 macrophage polarization.
MCTR1 inhibits ferroptosis by promoting NRF2 expression to attenuate hepatic ischemia-reperfusion injury.
Interaction between VPS13A and the XK scramblase is important for VPS13A function in humans.
Functional Phosphoproteomics in Cancer Chemoresistance Using CRISPR-Mediated Base Editors.
Generation of a homozygous P4HA2 knockout human embryonic stem cell line (FDCHDPe012-A) by CRISPR/Cas9 system.
Activation of DDX58/RIG‑I suppresses the growth of tumor cells by inhibiting STAT3/CSE signaling in colon cancer.
LIS1 interacts with CLIP170 to promote tumor growth and metastasis via the Cdc42 signaling pathway in salivary gland adenoid cystic carcinoma.
GDNF Promotes Astrocyte Abnormal Proliferation and Migration Through the GFRα1/RET/MAPK/pCREB/LOXL2 Signaling Axis.
TRIM47 promotes glioma angiogenesis by suppressing Smad4.
AKR1B10 accelerates the production of proinflammatory cytokines via the NF-κB signaling pathway in colon cancer.
Impact of ATP synthase/coupling factor 6 in hypoxic pulmonary arterial hypertension: An experimental rat model.
Depletion of serum-derived exosomes aggravates heat stress-induced damage of bovine mammary epithelial cells.
TMBIM6 promotes diabetic tubular epithelial cell survival and albumin endocytosis by inhibiting the endoplasmic reticulum stress sensor, IRE1α.
HIF-1α inhibits T-2 toxin-mediated "immune evasion" process by negatively regulating PD-1/PD-L1.
Promotion of angiogenesis in vitro by Astragalus polysaccharide via activation of TLR4 signaling pathway.
Proteasomal deubiquitylase activity enhances cell surface recycling of the epidermal growth factor receptor in non-small cell lung cancer.
Ulinastatin Alleviates Rhabdomyolysis-Induced Acute Kidney Injury by Suppressing Inflammation and Apoptosis via Inhibiting TLR4/NF-κB Signaling Pathway.
ADH1C inhibits progression of colorectal cancer through the ADH1C/PHGDH /PSAT1/serine metabolic pathway.
CYP24A1 Involvement in Inflammatory Factor Regulation Occurs via the Wnt Signaling Pathway.
Linear ubiquitination of PTEN impairs its function to promote prostate cancer progression.
Cdo1 promotes PPARγ-mediated adipose tissue lipolysis in male mice.
Pore-forming protein βγ-CAT promptly responses to fasting with capacity to deliver macromolecular nutrients.
Exosomes derived from mesenchymal stem cells attenuate diabetic kidney disease by inhibiting cell apoptosis and epithelial-to-mesenchymal transition via miR-424-5p.
MicroRNA-124 attenuates PTSD-like behaviors and reduces the level of inflammatory cytokines by downregulating the expression of TRAF6 in the hippocampus of rats following single-prolonged stress.
The phosphorylation and dephosphorylation switch of VCP/p97 regulates the architecture of centrosome and spindle.
Upregulation of Wilms' Tumor 1 in epicardial cells increases cardiac fibrosis in dystrophic mice.
Eplerenone ameliorates lung fibrosis in unilateral ureteral obstruction rats by inhibiting lymphangiogenesis.
TMEM14A aggravates the progression of human ovarian cancer cells by enhancing the activity of glycolysis.
FJX1 as a candidate diagnostic and prognostic serum biomarker for colorectal cancer.
KIAA1529 regulates RAD51 expression to confer PARP inhibitors resistance in ovarian cancer.
Effect of NMB-regulated ERK1/2 and p65 signaling pathway on proliferation and apoptosis of cervical cancer.
RNA-binding protein ELAVL4/HuD ameliorates Alzheimer's disease-related molecular changes in human iPSC-derived neurons.
Substance P promotes the progression of bronchial asthma through activating the PI3K/AKT/NF-κB pathway mediated cellular inflammation and pyroptotic cell death in bronchial epithelial cells.
Matrix metalloproteinase 3 restricts viral infection by enhancing host antiviral immunity.
MiR-582 Down-Regulates Lissencephaly-1 (LIS1) via P-Akt and MMP-2 to Inhibit Cholangiocarcinoma Cell Proliferation and Invasion.
Skin chronological aging drives age-related bone loss via secretion of cystatin-A.
Integrated Metabolomics and Network Pharmacology to Reveal the Mechanisms of Guizhi-Fuling Treatment for Myocardial Ischemia.
Induction of GLI1 by miR-27b-3p/FBXW7/KLF5 pathway contributes to pulmonary arterial hypertension.
MicroRNA-28-5p as a potential diagnostic biomarker for chronic periodontitis and its role in cell proliferation and inflammatory response.
SARM1 participates in axonal degeneration and mitochondrial dysfunction in prion disease.
miR-126 downregulates CXCL12 expression in intestinal epithelial cells to suppress the recruitment and function of macrophages and tumorigenesis in a murine model of colitis-associated colorectal cancer.
Blockade of IL-6 inhibits tumor immune evasion and improves anti-PD-1 immunotherapy.
Gegen Qinlian decoction ameliorates murine colitis by inhibiting the expansion of Enterobacteriaceae through activating PPAR-γ signaling.
Matrix metalloproteinase-7 promotes chronic kidney disease progression via the induction of inflammasomes and the suppression of autophagy.
Gentianella acuta improves TAC-induced cardiac remodelling by regulating the Notch and PI3K/Akt/FOXO1/3 pathways.
Mechanical stretch aggravates vascular smooth muscle cell apoptosis and vascular remodeling by downregulating EZH2.
The mechanism underlying the TC-G 1008 rescue of reactive oxygen species (ROS)-induced osteoblast apoptosis by the upregulation of peroxiredoxin 1.
Lithocarpus polystachyus (Sweet Tea) water extract promotes human hepatocytes HL7702 proliferation through activation of HGF/AKT/ERK signaling pathway.
Evaluation of Neurotoxicity in BALB/c Mice following Chronic Exposure to Polystyrene Microplastics.
LHX2 facilitates the progression of nasopharyngeal carcinoma via activation of the FGF1/FGFR axis.
Cucurbitacin B-induced G2/M cell cycle arrest of conjunctival melanoma cells mediated by GRP78-FOXM1-KIF20A pathway.
Eupalinolide B attenuates lipopolysaccharide-induced acute lung injury through inhibition of NF-κB and MAPKs signaling by targeting TAK1 protein.
Mycoplasma gallisepticum induced exosomal gga-miR-193a to disturb cell proliferation, apoptosis, and cytokine production by targeting the KRAS/ERK signaling pathway.
Secoisolariciresinol diglucoside-derived metabolite, enterolactone, attenuates atopic dermatitis by suppressing Th2 immune response.
The exon 12-containing LHX6 isoforms promote cervical cancer cell proliferation by regulating the MAPK signaling pathway.
The prognostic value and mechanisms of centromere protein M in patients with lung adenocarcinoma.
The application of proteomics and metabolomics to reveal the molecular mechanism of Nutmeg-5 in ameliorating cardiac fibrosis following myocardial infarction.
Demethylzeylasteral attenuates hepatic stellate cell activation and liver fibrosis by inhibiting AGAP2 mediated signaling.
Deletion of Smurf1 attenuates liver steatosis via stabilization of p53.
Effects of high-dose folic acid on protein metabolism in breast muscle and performance of broilers.
Platelet-rich plasma promotes diabetic ulcer repair through inhibition of ferroptosis.
Role of ROR2 in promoting gastric cancer metastasis by enhancing c-JUN-mediated MMP3 transcription.
CXCL12/CXCR7/β-arrestin1 biased signal promotes epithelial-to-mesenchymal transition of colorectal cancer by repressing miRNAs through YAP1 nuclear translocation.
Exosomal DNAJB11 promotes the development of pancreatic cancer by modulating the EGFR/MAPK pathway.
CircRNF144B/miR-342-3p/FBXL11 axis reduced autophagy and promoted the progression of ovarian cancer by increasing the ubiquitination of Beclin-1.
Discovery of an autophagy inducer J3 to lower mutant huntingtin and alleviate Huntington's disease-related phenotype.
An alternative mechanism for skeletal muscle dysfunction in long-term post-viral lung disease.
Generation of Flag/DYKDDDDK Epitope Tag Knock-In Mice Using i-GONAD Enables Detection of Endogenous CaMKIIα and β Proteins.
A20 Enhances the Expression of the Proto-Oncogene C-Myc by Downregulating TRAF6 Ubiquitination after ALV-A Infection.
Association of lithocholic acid with skeletal muscle hypertrophy through TGR5-IGF-1 and skeletal muscle mass in cultured mouse myotubes, chronic liver disease rats and humans.
The retracted conformation of ubiquitin Ser65 phosphorylation inhibits the formation of K48-linked ubiquitin chains.
Necrostatin-1 Alleviates Lung Ischemia-Reperfusion Injury via Inhibiting Necroptosis and Apoptosis of Lung Epithelial Cells.
Self-amplifying loop of NF-κB and periostin initiated by PIEZO1 accelerates mechano-induced senescence of nucleus pulposus cells and intervertebral disc degeneration.
circRNA422 enhanced osteogenic differentiation of bone marrow mesenchymal stem cells during early osseointegration through the SP7/LRP5 axis.
Identification of CPT2 as a prognostic biomarker by integrating the metabolism-associated gene signature in colorectal cancer.
Inhibition of Schwann cell pannexin 1 attenuates neuropathic pain through the suppression of inflammatory responses.
Upregulation of CRABP2 by TET1-mediated DNA hydroxymethylation attenuates mitochondrial apoptosis and promotes oxaliplatin resistance in gastric cancer.
NOP53 undergoes liquid-liquid phase separation and promotes tumor radio-resistance.
Inhibition of Netosis with PAD Inhibitor Attenuates Endotoxin Shock Induced Systemic Inflammation.
Z. morio Hemolymph Relieves E. coli-Induced Mastitis by Inhibiting Inflammatory Response and Repairing the Blood-Milk Barrier.
Rspondin-1 contributes to the progression and stemness of gastric cancer by LGR5.
TRAF4 promotes the malignant progression of high-grade serous ovarian cancer by activating YAP pathway.
Paraquat is an agonist of STIM1 and increases intracellular calcium levels.
Interferon-Inducible Transmembrane Protein 3 (IFITM3) Restricts Rotavirus Infection.
VAMP4 regulates insulin levels by targeting secretory granules to lysosomes.
Impaired XK recycling for importing manganese underlies striatal vulnerability in Huntington's disease.
Fucoxanthin induces apoptosis and reverses epithelial-mesenchymal transition via inhibiting Wnt/β-catenin pathway in lung adenocarcinoma.
An optimized exosome production strategy for enhanced yield while without sacrificing cargo loading efficiency.
Knockdown of METTL16 disrupts learning and memory by reducing the stability of MAT2A mRNA.
ITGA2 overexpression inhibits DNA repair and confers sensitivity to radiotherapies in pancreatic cancer.
Peimine ameliorates pulmonary fibrosis via the inhibition of M2-type macrophage polarization through the suppression of P38/Akt/STAT6 signals.
MICALL2 as a substrate of ubiquitinase TRIM21 regulates tumorigenesis of colorectal cancer.
Arrest of Cell Cycle by Avian Reovirus p17 through Its Interaction with Bub3.
Extracellular vesicles microRNA-592 of melanoma stem cells promotes metastasis through activation of MAPK/ERK signaling pathway by targeting PTPN7 in non-stemness melanoma cells.
Inhibition of SRPK1, a key splicing regulator, exhibits antitumor and chemotherapeutic-sensitizing effects on extranodal NK/T-cell lymphoma cells.
Calcium transients on the ER surface trigger liquid-liquid phase separation of FIP200 to specify autophagosome initiation sites.
An assembly-inducing PDC enabling the efficient nuclear delivery of nucleic acid for cancer stem-like cell suppression.
Jian-Pi-Yi-Shen decoction inhibits mitochondria-dependent granulosa cell apoptosis in a rat model of POF.
Senescent neutrophils-derived exosomal piRNA-17560 promotes chemoresistance and EMT of breast cancer via FTO-mediated m6A demethylation.
Oral Microbiota from Periodontitis Promote Oral Squamous Cell Carcinoma Development via γδ T Cell Activation.
GSK872 and necrostatin-1 protect retinal ganglion cells against necroptosis through inhibition of RIP1/RIP3/MLKL pathway in glutamate-induced retinal excitotoxic model of glaucoma.
Multi-omics characterization of autophagy-related molecular features for therapeutic targeting of autophagy.
ACSL1 promotes imatinib-induced chronic myeloid leukemia cell senescence by regulating SIRT1/p53/p21 pathway.
ER-phagy Is Involved in the Degradation of Collagen I by IL-1β in Human Amnion in Parturition.
m(6)A modification confers thermal vulnerability to HPV E7 oncotranscripts via reverse regulation of its reader protein IGF2BP1 upon heat stress.
Circulating small extracellular vesicle-encapsulated SEMA5A-IT1 attenuates myocardial ischemia-reperfusion injury after cardiac surgery with cardiopulmonary bypass.
LncRNA LINC01537 Promotes Gastric Cancer Metastasis and Tumorigenesis by Stabilizing RIPK4 to Activate NF-κB Signaling.
Metabolic Responses and Pathway Changes of Vero Cells under High-Vitamin B Medium.
Schwann cells-derived exosomal miR-21 participates in high glucose regulation of neurite outgrowth.
Induced retinal pigment epithelial cells with anti-epithelial-to-mesenchymal transition ability delay retinal degeneration.
Single cell transcriptomic profiling of a neuron-astrocyte assembloid tauopathy model.
Renoprotective effect of Tanshinone IIA against kidney injury induced by ischemia-reperfusion in obese rats.
In Vitro and In Vivo Evaluation of Antidiabetic Properties and Mechanisms of Ficus tikoua Bur.
PDCL2 is essential for spermiogenesis and male fertility in mice.
Trilobatin alleviates non-alcoholic fatty liver disease in high-fat diet plus streptozotocin-induced diabetic mice by suppressing NLRP3 inflammasome activation.
p-TAK1 acts as a switch between myoblast proliferation phase and differentiation phase in mdx mice via regulating HO-1 expression.
Malvidin protects against lipopolysaccharide-induced acute liver injury in mice via regulating Nrf2 and NLRP3 pathways and suppressing apoptosis and autophagy.
αSMA-Cre-mediated Ogt deletion leads to heart failure and vascular smooth muscle cell dysfunction in mice.
Mitophagy induced by classical swine fever virus nonstructural protein 5A promotes viral replication.
Role of RNA m(6)A modification in titanium dioxide nanoparticle-induced acute pulmonary injury: An in vitro and in vivo study.
Obeticholic acid aggravates liver injury by up-regulating the liver expression of osteopontin in obstructive cholestasis.
Transcriptional factor III A promotes colorectal cancer progression by upregulating cystatin A.
Subcellular partitioning of protein kinase activity revealed by functional kinome profiling.
CLDN1 Sensitizes Triple-Negative Breast Cancer Cells to Chemotherapy.
DAZAP1 facilitates the alternative splicing of KITLG to promote multiple myeloma cell proliferation via ERK signaling pathway.
Melatonin Prevents against Ethanol-Induced Liver Injury by Mitigating Ferroptosis via Targeting Brain and Muscle ARNT-like 1 in Mice Liver and HepG2 Cells.
Targeting UBR5 in hepatocellular carcinoma cells and precise treatment via echinacoside nanodelivery.
STING pathway contributes to the prognosis of hepatocellular carcinoma and identification of prognostic gene signatures correlated to tumor microenvironment.
Targeting EGFR-dependent tumors by disrupting an ARF6-mediated sorting system.
PSD-95 in the anterior cingulate cortex contributes to neuropathic pain by interdependent activation with NR2B.
Vimentin inhibits type I interferon production by disrupting the TBK1-IKKε-IRF3 axis.
LARRPM restricts lung adenocarcinoma progression and M2 macrophage polarization through epigenetically regulating LINC00240 and CSF1.
Jatrorrhizine Improves Endothelial Function in Diabetes and Obesity through Suppression of Endoplasmic Reticulum Stress.
CGG repeat expansion in NOTCH2NLC causes mitochondrial dysfunction and progressive neurodegeneration in Drosophila model.
ISG20L2 suppresses bortezomib antimyeloma activity by attenuating bortezomib binding to PSMB5.
Micronuclei from misaligned chromosomes that satisfy the spindle assembly checkpoint in cancer cells.
RAI14 Promotes Melanoma Progression by Regulating the FBXO32/c-MYC Pathway.
Neurogranin inhibits calcineurin in murine soleus muscle: Effects of heterozygous knockdown on muscle adaptations to tenotomy and fatigue resistance.
The matrix protein of Newcastle disease virus inhibits inflammatory response through IRAK4/TRAF6/TAK1/NF-κB signaling pathway.
Influence of Boron Neutron Capture Therapy on Normal Liver Tissue.
Inactivation of fatty acid amide hydrolase protects against ischemic reperfusion injury-induced renal fibrogenesis.
Locomotor Hyperactivity in the Early-Stage Alzheimer's Disease-like Pathology of APP/PS1 Mice: Associated with Impaired Polarization of Astrocyte Aquaporin 4.
UPP1 Promotes Lung Adenocarcinoma Progression through Epigenetic Regulation of Glycolysis.
Role of estrogen receptors in thyroid toxicity induced by mono (2-ethylhexyl) phthalate via endoplasmic reticulum stress: An in vitro mechanistic investigation.
Blood-brain barrier permeability to enrofloxacin in Pengze crucian carp (Carassius auratus var. Pengze).
SENP3 Aggravates Renal Tubular Epithelial Cell Apoptosis in Lipopolysaccharide-Induced Acute Kidney Injury via deSUMOylation of Drp1.
Plasma exosomal miR-122 regulates the efficacy of metformin via AMPK in type 2 diabetes and hepatocellular carcinoma.
Tumor suppressor LHPP suppresses cell proliferation and epithelial-mesenchymal transition in hepatocellular carcinoma cell lines.
Orphan nuclear receptor NUR77 relieves insulin resistance in HTR-8/SVneo trophoblast cells through activation of autophagy and insulin signaling.
In vivo fluorescent screening for HPPD-targeted herbicide discovery.
Proteomic analysis and identification reveal the anti-inflammatory mechanism of clofazimine on lipopolysaccharide-induced acute lung injury in mice.
Identification of a Feed-Forward Loop Between 15(S)-HETE and PGE2 in Human Amnion at Parturition.
Subtype-specific 3D genome alteration in acute myeloid leukaemia.
Selenoprotein K contributes to CD36 subcellular trafficking in hepatocytes by accelerating nascent COPII vesicle formation and aggravates hepatic steatosis.
Hypotonic induction of aquaporin5 expression in rat astrocytes through p38 MAPK pathway.
Lack of bombesin receptor-activated protein attenuates bleomycin-induced pulmonary fibrosis in mice.
Atypical chemokine receptor 3 induces colorectal tumorigenesis in mice by promoting β-arrestin-NOLC1-fibrillarin-dependent rRNA biogenesis.
Intratracheal instillation of graphene oxide decreases anti-virus responses and lipid contents via suppressing Toll-like receptor 3 in mouse livers.
Metformin suppresses vascular smooth muscle cell senescence by promoting autophagic flux.
The ubiquitin-specific protease 8 antagonizes melatonin-induced endocytic degradation of MT(1) receptor to promote lung adenocarcinoma growth.
Selenium-sensitive histone deacetylase 2 is required for forkhead box O3A and regulates extracellular matrix metabolism in cartilage.
GRAP2 is a prognostic biomarker and correlated with immune infiltration in lung adenocarcinoma.
circBGN accelerates gastric cancer cell proliferation and invasion via activating IL6/STAT3 signaling pathway.
Disturbing NLRP3 acetylation and inflammasome assembly inhibits androgen receptor-promoted inflammatory responses and prostate cancer progression.
Berbamine hydrochloride inhibits bovine viral diarrhea virus replication via interfering in late-stage autophagy.
Chaperoning activity of the cyclophilin family prevents tau aggregation.
p38α in the preoptic area inhibits brown adipose tissue thermogenesis.
Aurora A-mediated pyruvate kinase M2 phosphorylation promotes biosynthesis with glycolytic metabolites and tumor cell cycle progression.
Enhanced membrane binding of oncogenic G protein αqQ209L confers resistance to inhibitor YM-254890.
Loss of RBMS1 promotes anti-tumor immunity through enabling PD-L1 checkpoint blockade in triple-negative breast cancer.
Wnt/beta-catenin signaling confers ferroptosis resistance by targeting GPX4 in gastric cancer.
Molecular cloning, functional characterization of duck TRADD and its effect on infection with duck Tembusu virus.
African swine fever virus pE301R negatively regulates cGAS-STING signaling pathway by inhibiting the nuclear translocation of IRF3.
NOD2-mediated HDAC6/NF-κb signalling pathway regulates ferroptosis induced by extracellular histone H3 in acute liver failure.
Expression profile of immunoregulatory factors in canine tumors.
Celastrol attenuates renal injury in 5/6 nephrectomized rats via inhibiting epithelial-mesenchymal transition and transforming growth factor-β1/Smad3 pathway.
MG132 protects against lung injury following brain death in rats.
Chemerin promotes MAPK/ERK activation to induce inflammatory factor production in rat synoviocytes.
Ac2‑26 alleviates hepatic ischemia‑reperfusion injury based on inhibiting the positive feedback loop of HMGB1/TLR4/NF‑κB/neutrophils.
IL-17D-induced inhibition of DDX5 expression in keratinocytes amplifies IL-36R-mediated skin inflammation.
Transcription factor NFE2L3 promotes the proliferation of esophageal squamous cell carcinoma cells and causes radiotherapy resistance by regulating IL-6.
Legumain affects the PI3K/AKT tumor progression pathway in retinoblastoma.
The effect and mechanistic study of encequidar on reversing the resistance of SW620/AD300 cells to doxorubicin.
Upstream stimulatory factor 2 inhibits erastin-induced ferroptosis in pancreatic cancer through transcriptional regulation of pyruvate kinase M2.
Monoterpenoid indole alkaloid dimers from Kopsia arborea inhibit cyclin-dependent kinase 5 and tau phosphorylation.
Antifibrotic pyridine-containing monoterpene alkaloids from Caryopteris glutinosa.
USP17L2-SIRT7 axis regulates DNA damage repair and chemoresistance in breast cancer cells.
Exposure to Multiwall Carbon Nanotubes Promotes Fibrous Proliferation by Production of Matrix Metalloproteinase-12 via NF-κB Activation in Chronic Peritonitis.
Chromatin-remodeling factor BAZ1A/ACF1 targets UV damage sites in an MLL1-dependent manner to facilitate nucleotide excision repair.
A novel oncotherapy strategy: Direct thrombin inhibitors suppress progression, dissemination and spontaneous metastasis in non-small cell lung cancer.
The effects of scoparone on alcohol and high-fat diet-induced liver injury revealed by RNA sequencing.
The dipeptidyl peptidase-4 inhibitor linagliptin ameliorates LPS-induced acute lung injury by maintenance of pulmonary microvascular barrier via activating the Epac1/AKT pathway.
Lysophosphatidylcholine acyltransferase 1 alleviates silica-induced pulmonary fibrosis by modulating lipid metabolism.
CHRNA5 Is Overexpressed in Patients with Psoriasis and Promotes Psoriasis-Like Inflammation in Mouse Models.
Molecular characterization of the evolutionary conserved signaling intermediate in Toll pathways (ECSIT) of soiny mullet (Liza haematocheila).
The m(6)A methyltransferase METTL3 promotes trophoblast cell invasion by regulating MYLK expression.
Diterpenoids from the whole plant of Euphorbia wallichii and their protective effects on H(2)O(2)-induced BV-2 microglial cells injury.
HSP90B1 overexpression is associated with poor prognosis in tongue squamous cell carcinoma.
Pancreatic ductal adenocarcinoma cells regulated the gemcitabine-resistance function of CAFs by LINC00460.
Apelin-mediated deamidation of HMGA1 promotes tumorigenesis by enhancing SREBP1 activity and lipid synthesis.
TaFDL2-1A confers drought stress tolerance by promoting ABA biosynthesis, ABA responses, and ROS scavenging in transgenic wheat.
Phellopterin alleviates atopic dermatitis-like inflammation and suppresses IL-4-induced STAT3 activation in keratinocytes.
Myotubularin-Related Protein14 Prevents Neointima Formation and Vascular Smooth Muscle Cell Proliferation by Inhibiting Polo-Like Kinase1.
Identification of FDFT1 as a potential biomarker associated with ferroptosis in ccRCC.
Ginsenoside Rg1 promotes remyelination and functional recovery in demyelinating disease by enhancing oligodendrocyte precursor cells-mediated myelin repair.
Zika Virus Infection Downregulates Connexin 43, Disrupts the Cardiomyocyte Gap Junctions and Induces Heart Diseases in A129 Mice.
Regulation of sleep quantity and intensity by long and short isoforms of SLEEPY kinase.
ATP Promotes Oral Squamous Cell Carcinoma Cell Invasion and Migration by Activating the PI3K/AKT Pathway via the P2Y2-Src-EGFR Axis.
Targeting the MITF/APAF-1 axis as salvage therapy for MAPK inhibitors in resistant melanoma.
UNC13D inhibits STING signaling by attenuating its oligomerization on the endoplasmic reticulum.
The RNA polymerase II subunit Rpb9 activates ATG1 transcription and autophagy.
TRIM50 promotes NLRP3 inflammasome activation by directly inducing NLRP3 oligomerization.
Mouse Bone Marrow Mesenchymal Stem Cells Inhibit Sepsis-Induced Lung Injury in Mice via Exosomal SAA1.
MiR-29a inhibits MPP + - Induced cell death and inflammation in Parkinson's disease model in vitro by potential targeting of MAVS.
RBM10 regulates alternative splicing of lncRNA Neat1 to inhibit the invasion and metastasis of NSCLC.
Irradiation-induced exosomal HMGB1 to confer radioresistance via the PI3K/AKT/FOXO3A signaling pathway in ESCC.
Synthesis and Biological Evaluation of Cardiac Glycosides for Cancer Therapy by Targeting the DNA Damage Response.
Pterostilbene attenuates intrauterine growth retardation-induced colon inflammation in piglets by modulating endoplasmic reticulum stress and autophagy.
RNA-seq transcriptomic analysis of 4-octyl itaconate repressing myogenic differentiation.
Sevoflurane-induced POCD-associated exosomes delivered miR-584-5p regulates the growth of human microglia HMC3 cells through targeting BDNF.
Metformin alleviates HFD-induced oxidative stress in hepatocyte via activating SIRT6/PGC-1α/ENDOG signaling.
TGF-β2 Regulates Transcription of the K(+)/Cl(-) Cotransporter 2 (KCC2) in Immature Neurons and Its Phosphorylation at T1007 in Differentiated Neurons.
Tim-4 reprograms cholesterol metabolism to suppress antiviral innate immunity by disturbing the Insig1-SCAP interaction in macrophages.
Social deficits via dysregulated Rac1-dependent excitability control of prefrontal cortical neurons and increased GABA/glutamate ratios.
Integrative Proteomics and Transcriptomics Profiles of the Oviduct Reveal the Prolificacy-Related Candidate Biomarkers of Goats (Capra hircus) in Estrous Periods.
Regulation of ZO-1 on β-catenin mediates sulforaphane suppressed colorectal cancer stem cell properties in colorectal cancer.
SRSF3 and HNRNPH1 Regulate Radiation-Induced Alternative Splicing of Protein Arginine Methyltransferase 5 in Hepatocellular Carcinoma.
The proatherosclerotic function of BCAT1 in atherosclerosis development of aged-apolipoprotein E-deficient mice.
Discovery of a Novel Bloom's Syndrome Protein (BLM) Inhibitor Suppressing Growth and Metastasis of Prostate Cancer.
Expression of expanded GGC repeats within NOTCH2NLC causes behavioral deficits and neurodegeneration in a mouse model of neuronal intranuclear inclusion disease.
An insecticide target in mechanoreceptor neurons.
Pt(IV) Prodrug as a Potential Antitumor Agent with APE1 Inhibitory Activity.
Blockade of Kv1.3 Potassium Channel Inhibits Microglia-Mediated Neuroinflammation in Epilepsy.
New Baitouweng decoction combined with fecal microbiota transplantation alleviates DSS-induced colitis in rats by regulating gut microbiota metabolic homeostasis and the STAT3/NF-κB signaling pathway.
Integrated metabolomics, network pharmacology and biological verification to reveal the mechanisms of Nauclea officinalis treatment of LPS-induced acute lung injury.
Diosgenin Ameliorated Type II Diabetes-Associated Nonalcoholic Fatty Liver Disease through Inhibiting De Novo Lipogenesis and Improving Fatty Acid Oxidation and Mitochondrial Function in Rats.
Aberrant amino acid metabolism promotes neurovascular reactivity in rosacea.
circPRKAA1 activates a Ku80/Ku70/SREBP-1 axis driving de novo fatty acid synthesis in cancer cells.
Dynamic quality control machinery that operates across compartmental borders mediates the degradation of mammalian nuclear membrane proteins.
Neutrophil Nanovesicle Protects against Experimental Autoimmune Encephalomyelitis through Enhancing Myelin Clearance by Microglia.
IL-37 alleviates Coxsackievirus B3-induced viral myocarditis via inhibiting NLRP3 inflammasome-mediated pyroptosis.
Naringenin Promotes Myotube Formation and Maturation for Cultured Meat Production.
Apigenin Ameliorates Hyperuricemia and Renal Injury through Regulation of Uric Acid Metabolism and JAK2/STAT3 Signaling Pathway.
RSAD2 Is an Effective Target for High-Yield Vaccine Production in MDCK Cells.
NMN ameliorated radiation induced damage in NRF2-deficient cell and mice via regulating SIRT6 and SIRT7.
Cell-cell contact-driven EphB1 cis- and trans- signalings regulate cancer stem cells enrichment after chemotherapy.
BRAF activation by metabolic stress promotes glycolysis sensitizing NRAS(Q61)-mutated melanomas to targeted therapy.
Swine acute diarrhea syndrome coronavirus induces autophagy to promote its replication via the Akt/mTOR pathway.
Cancer cell intrinsic TIM-3 induces glioblastoma progression.
Identification of purine biosynthesis as an NADH-sensing pathway to mediate energy stress.
m(6)A modification of circSPECC1 suppresses RPE oxidative damage and maintains retinal homeostasis.
N6-methyladenosine modification on Hmbox1 is related to telomere dysfunction in DEHP-induced male reproductive injury.
Sophocarpine Alleviates Isoproterenol-Induced Kidney Injury by Suppressing Inflammation, Apoptosis, Oxidative Stress and Fibrosis.
Methyl Gallate Alleviates Acute Ulcerative Colitis by Modulating Gut Microbiota and Inhibiting TLR4/NF-κB Pathway.
A SERPINE1-Based Immune Gene Signature Predicts Prognosis and Immunotherapy Response in Gastric Cancer.
Dissecting Heterogeneity Reveals a Unique BAMBI(high) MFGE8(high) Subpopulation of Human UC-MSCs.
A novel Granzymes and miRNA nanocapsules co-delivery system for tumor suppression.
METTL3-mediated m6A modification stabilizes TERRA and maintains telomere stability.
Dihydrotanshinone I Inhibits the Proliferation and Growth of Oxaliplatin-Resistant Human HCT116 Colorectal Cancer Cells.
Deubiquitinase USP35 stabilizes BRPF1 to activate mevalonate (MVA) metabolism during prostate tumorigenesis.
Systematic characterization of cancer transcriptome at transcript resolution.
Obese Skeletal Muscle-Expressed Interferon Regulatory Factor 4 Transcriptionally Regulates Mitochondrial Branched-Chain Aminotransferase Reprogramming Metabolome.
Exosome-derived FGD5-AS1 promotes tumor-associated macrophage M2 polarization-mediated pancreatic cancer cell proliferation and metastasis.
Acute depletion of human core nucleoporin reveals direct roles in transcription control but dispensability for 3D genome organization.
Effects of apolipoprotein E on regulating insulin sensitivity via regulating insulin receptor signalosome in caveolae.
Bufalin Inhibits Tumorigenesis, Stemness, and Epithelial-Mesenchymal Transition in Colorectal Cancer through a C-Kit/Slug Signaling Axis.
Optimized Transcriptional Signature for Evaluation of MEK/ERK Pathway Baseline Activity and Long-Term Modulations in Ovarian Cancer.
Potential mechanisms underlying the promoting effects of 3D collagen scaffold culture on stemness and drug resistance of glioma cells.
Effects of the m6Am methyltransferase PCIF1 on cell proliferation and survival in gliomas.
Activation of the Aryl Hydrocarbon Receptor Ameliorates Acute Rejection of Rat Liver Transplantation by Regulating Treg Proliferation and PD-1 Expression.
Salidroside protects against osteoporosis in ovariectomized rats by inhibiting oxidative stress and promoting osteogenesis via Nrf2 activation.
MiR-1298-5p level downregulation induced by Helicobacter pylori infection inhibits autophagy and promotes gastric cancer development by targeting MAP2K6.
Ubiquitin ligase DTX3 empowers mutant p53 to promote ovarian cancer development.
Collagen peptides from Acaudina molpadioides prevent CCl(4) -induced liver injury via Keap1/Nrf2-ARE, PI3K/AKT, and MAPKs pathways.
Sinapic acid inhibits pancreatic cancer proliferation, migration, and invasion via downregulation of the AKT/Gsk-3β signal pathway.
Renal tubule ectopic lipid deposition in diabetic kidney disease rat model and in vitro mechanism of leptin intervention.
Hippocampal Activated Microglia May Contribute to Blood-Brain Barrier Impairment and Cognitive Dysfunction in Post-Traumatic Stress Disorder-Like Rats.
Macrophage-targeted delivery of siRNA to silence Mecp2 gene expression attenuates pulmonary fibrosis.
Novel lissencephaly-associated DCX variants in the C-terminal DCX domain affect microtubule binding and dynamics.
Adrenomedullin ameliorates palmitic acid-induced insulin resistance through PI3K/Akt pathway in adipocytes.
Quercetin Alleviates Demyelination Through Regulating Microglial Phenotype Transformation to Mitigate Neuropsychiatric Symptoms in Mice with Vascular Dementia.
The interaction of O-GlcNAc-modified NLRX1 and IKK-α modulates IL-1β expression in M1 macrophages.
Antioxidant and Immunomodulatory Properties of Partially purified Exopolysaccharide from Lactobacillus Casei Isolated from Chinese Northeast Sauerkraut.
Long Noncoding RNAs Hepatocyte Nuclear Factor 4A Antisense RNA 1 and Hepatocyte Nuclear Factor 1A Antisense RNA 1 Are Involved in Ritonavir-Induced Cytotoxicity in Hepatoma Cells.
CCL2 activates AKT signaling to promote glycolysis and chemoresistance in glioma cells.
PFOS facilitates liver inflammation and steatosis: An involvement of NLRP3 inflammasome-mediated hepatocyte pyroptosis.
CRL2(KLHDC3) mediates p14ARF N-terminal ubiquitylation degradation to promote non-small cell lung carcinoma progression.
RNA N6-methyladenosine demethylase FTO promotes pancreatic cancer progression by inducing the autocrine activity of PDGFC in an m(6)A-YTHDF2-dependent manner.
microRNA-1321 and microRNA-7515 contribute to the progression of non-small cell lung cancer by targeting CDC20.
Selenium protects against cadmium-induced cardiac injury by attenuating programmed cell death via PI3K/AKT/PTEN signaling.
Blocking PARP activity with the inhibitor veliparib enhances radiotherapy sensitivity in endometrial carcinoma.
Nrf2 improves hippocampal synaptic plasticity, learning and memory through the circ-Vps41/miR-26a-5p/CaMKIV regulatory network.
Correlation of vascular change with TRPV1, TRPV4, and TRPA1 in a rat model of inferior gluteal artery perforator flap.
Capsaicin inhibits intestinal Cl(-) secretion and promotes Na(+) absorption by blocking TRPV4 channels in healthy and colitic mice.
An miRNA derived from amelogenin exon4 regulates expression of transcription factor Runx2 by directly targeting upstream activators Nfia and Prkch.
Dibutyltin dichloride exposure affects mouse oocyte quality by inducing spindle defects and mitochondria dysfunction.
The application of CRISPR/Cas9 system in cervical carcinogenesis.
Involvement of calcium homeostasis and unfolded protein response in autophagy co-induced by molybdenum and cadmium in duck (Anas platyrhyncha) brain.
PM(2.5) causes vascular hyperreactivity through the upregulation of the thromboxane A(2) receptor and activation of MAPK pathways.
Naturally occurring UBIAD1 mutations differentially affect menaquinone biosynthesis and vitamin K-dependent carboxylation.
Type IIB PKA is highly expressed in β cells and controls cell proliferation via regulating Cyclin D1 expression.
Evaluation of the TRIP13 level in breast cancer and insights into potential molecular pathways.
Novel chloroquine derivative suppresses melanoma cell growth by DNA damage through increasing ROS levels.
Leukemia inhibitory factor is dysregulated in ankylosing spondylitis and contributes to bone formation.
LncRNA SOX2OT facilitates LPS-induced inflammatory injury by regulating intercellular adhesion molecule 1 (ICAM1) via sponging miR-215-5p.
Radix ranunculus temate saponins sensitizes ovarian cancer to Taxol via upregulation of miR-let-7b.
A synapsin Ⅰ cleavage fragment contributes to synaptic dysfunction in Alzheimer's disease.
Human and mouse PAR4 are functionally distinct receptors: Studies in novel humanized mice.
In vivo cyclic induction of the FOXM1 transcription factor delays natural and progeroid aging phenotypes and extends healthspan.
Metformin increases the radiosensitivity of non-small cell lung cancer cells by destabilizing NRF2.
Exosomal MMP-1 transfers metastasis potential in triple-negative breast cancer through PAR1-mediated EMT.
Dihydroflavonoids as Bioactive Components of Penthorum chinense, a Miao Ethnomedicine, against NAFLD through Bile Acid Metabolism Pathway.
Comparative subcellular localization of NRF2 and KEAP1 during the hepatocellular carcinoma development in vivo.
Increased alveolar epithelial TRAF6 via autophagy-dependent TRIM37 degradation mediates particulate matter-induced lung metastasis.
Pubertal changes in the pituitary and adrenal glands of male and female rats: Relevance to stress reactivity.
Intrinsic features of Zika Virus non-structural proteins NS2A and NS4A in the regulation of viral replication.
Nanoformulation of a carbon monoxide releasing molecule protects against cyclosporin A-induced nephrotoxicity and renal fibrosis via the suppression of the NLRP3 inflammasome mediated TGF-β/Smad pathway.
A novel ribosomal protein S6 kinase 2 inhibitor attenuates the malignant phenotype of cutaneous malignant melanoma cells by inducing cell cycle arrest and apoptosis.
Sex-determining Region Y-box transcription factor 13 promotes breast cancer cell proliferation and glycolysis by activating the tripartite motif containing 11-mediated Wnt/β-catenin signaling pathway.
MicroRNA-744-5p suppresses tumorigenesis and metastasis of osteosarcoma through the p38 mitogen-activated protein kinases pathway by targeting transforming growth factor-beta 1.
Long non-coding RNA lincRNA-erythroid prosurvival (EPS) alleviates cerebral ischemia/reperfusion injury by maintaining high-temperature requirement protein A1 (Htra1) stability through recruiting heterogeneous nuclear ribonucleoprotein L (HNRNPL).
Characterization of the Eimeria tenella rhoptry protein with a nuclear localization sequence (EtROP30).
Genome-wide gain-of-function screening identifies EZH2 mediating resistance to PI3Kα inhibitors in oesophageal squamous cell carcinoma.
MicroRNA-34c-5p provokes isoprenaline-induced cardiac hypertrophy by modulating autophagy via targeting ATG4B.
Flunarizine suppresses Mycobacterium tuberculosis growth via calmodulin-dependent phagosome maturation.
Activation of the ATX/LPA/LPARs axis induces a fibrotic response in skeletal muscle.
Mitochondria-specific peptide amphiphiles induce mitochondrial dysfunction and peripheral T-cell lymphomas (PTCL) damage.
Deletion of the miR-144/451 cluster aggravates lethal sepsis-induced lung epithelial oxidative stress and apoptosis.
Functional genetic screen identifies ITPR3/calcium/RELB axis as a driver of colorectal cancer metastatic liver colonization.
C/EBPβ mediates anti-proliferative effects of 1,25(OH)2D on differentiated thyroid carcinoma cells.
PAFAH1B3 predicts poor prognosis and promotes progression in lung adenocarcinoma.
Oncopeptide MBOP Encoded by LINC01234 Promotes Colorectal Cancer through MAPK Signaling Pathway.
Gga-miR-30c-5p Enhances Apoptosis in Fowl Adenovirus Serotype 4-Infected Leghorn Male Hepatocellular Cells and Facilitates Viral Replication through Myeloid Cell Leukemia-1.
Hypoxic mesenchymal stem cell-derived extracellular vesicles ameliorate renal fibrosis after ischemia-reperfusion injure by restoring CPT1A mediated fatty acid oxidation.
Nuclear and cytoplasmic poly(A) binding proteins (PABPs) favor distinct transcripts and isoforms.
Z-DNA binding protein 1 promotes heatstroke-induced cell death.
Cytochrome P450 2E1 predicts liver functional recovery from donation after circulatory death using air-ventilated normothermic machine perfusion.
Viperin triggers ribosome collision-dependent translation inhibition to restrict viral replication.
FAM126A interacted with ENO1 mediates proliferation and metastasis in pancreatic cancer via PI3K/AKT signaling pathway.
The Cytoskeleton Effectors Rho-Kinase (ROCK) and Mammalian Diaphanous-Related (mDia) Formin Have Dynamic Roles in Tumor Microtube Formation in Invasive Glioblastoma Cells.
Dysregulation of the miR-30c/DLL4 axis by circHIPK3 is essential for KSHV lytic replication.
PFKP alleviates glucose starvation-induced metabolic stress in lung cancer cells via AMPK-ACC2 dependent fatty acid oxidation.
LXRα Regulates oxLDL-Induced Trained Immunity in Macrophages.
Changes in the Transcriptome Caused by Mutations in the Ribosomal Protein uS10 Associated with a Predisposition to Colorectal Cancer.
Natural antisense RNA Foxk1-AS promotes myogenic differentiation by inhibiting Foxk1 activity.
Poly(A)-Binding Protein Cytoplasmic 1 Inhibits Porcine Epidemic Diarrhea Virus Replication by Interacting with Nucleocapsid Protein.
Comprehensive Analysis and Experimental Validation of a Novel Estrogen/Progesterone-Related Prognostic Signature for Endometrial Cancer.
The two-faced role of ATF2 on cisplatin response in gastric cancer depends on p53 context.
Whole body vibration activates AMPK/CPT1 signaling pathway of skeletal muscle in young and aging mice based on metabolomics study.
Eukaryotic Initiation Factor 5A2 Regulates Expression of Antiviral Genes.
The Establishment of a Mouse Model of Recurrent Primary Dysmenorrhea.
TGF-β1 regulates chondrocyte proliferation and extracellular matrix synthesis via circPhf21a-Vegfa axis in osteoarthritis.
miR-600 promotes ovarian cancer cells stemness, proliferation and metastasis via targeting KLF9.
Pentamethylquercetin Regulates Lipid Metabolism by Modulating Skeletal Muscle-Adipose Tissue Crosstalk in Obese Mice.
Hernandezine Regulates Proliferation and Autophagy-Induced Apoptosis in Melanoma Cells.
Mechanism of INSR clustering with insulin activation and resistance revealed by super-resolution imaging.
β-amyloid protein induces mitophagy-dependent ferroptosis through the CD36/PINK/PARKIN pathway leading to blood-brain barrier destruction in Alzheimer's disease.
TARDBP Inhibits Porcine Epidemic Diarrhea Virus Replication through Degrading Viral Nucleocapsid Protein and Activating Type I Interferon Signaling.
Kif4A mediates resistance to neoadjuvant chemoradiotherapy in patients with advanced colorectal cancer via regulating DNA damage response.
Cholecystectomy promotes colon carcinogenesis by activating the Wnt signaling pathway by increasing the deoxycholic acid level.
Role of EZH2-mediated H3K27me3 in placental ADAM12-S expression: implications for fetoplacental growth.
Aberrant methylmalonylation underlies methylmalonic acidemia and is attenuated by an engineered sirtuin.
Role of Nrf2 Nucleus Translocation in Beauvericin-Induced Cell Damage in Rat Hepatocytes.
FAT10 promotes chemotherapeutic resistance in pancreatic cancer by inducing epithelial-mesenchymal transition via stabilization of FOXM1 expression.
Blocking STAT3 signaling augments MEK/ERK inhibitor efficacy in esophageal squamous cell carcinoma.
MiR-135a-5p suppresses trophoblast proliferative, migratory, invasive, and angiogenic activity in the context of unexplained spontaneous abortion.
Brasilterpenes A-E, Bergamotane Sesquiterpenoid Derivatives with Hypoglycemic Activity from the Deep Sea-Derived Fungus Paraconiothyrium brasiliense HDN15-135.
Co-interventions with Clostridium butyricum and soluble dietary fiber targeting the gut microbiota improve MAFLD via the Acly/Nrf2/NF-κB signaling pathway.
Blockade LAT1 Mediates Methionine Metabolism to Overcome Oxaliplatin Resistance under Hypoxia in Renal Cell Carcinoma.
Sulforaphane protects myocardium from ischemia-reperfusion injury by regulating CaMKIIN2 and CaMKIIδ.
Dedicator of Cytokinesis 2 (DOCK2) Silencing Protects Against Cerebral Ischemia/Reperfusion by Modulating Microglia Polarization via the Activation of the STAT6 Signaling Pathway.
METTL16 promotes hepatocellular carcinoma progression through downregulating RAB11B-AS1 in an m(6)A-dependent manner.
A comprehensive analysis of potential gastric cancer prognostic biomarker ITGBL1 associated with immune infiltration and epithelial-mesenchymal transition.
Inhibition of the CDK2 and Cyclin A complex leads to autophagic degradation of CDK2 in cancer cells.
FBXW2 inhibits prostate cancer proliferation and metastasis via promoting EGFR ubiquitylation and degradation.
FNIP1 regulates adipocyte browning and systemic glucose homeostasis in mice by shaping intracellular calcium dynamics.
Scorpion and centipede alleviates severe asthma through M2 macrophage-derived exosomal miR-30b-5p.
Pseudorabies Virus ICP0 Abolishes Tumor Necrosis Factor Alpha-Induced NF-κB Activation by Degrading P65.
UHMK1 aids colorectal cancer cell proliferation and chemoresistance through augmenting IL-6/STAT3 signaling.
Filamentous GLS1 promotes ROS-induced apoptosis upon glutamine deprivation via insufficient asparagine synthesis.
Temporal regulation of interferon signalling in human EndoC-βH1 cells.
Cystathionine-β-synthase (CBS)/H2S system promotes lymph node metastasis of esophageal squamous cell carcinoma (ESCC) by activating SIRT1.
Protective effect of homogeneous polysaccharides of Wuguchong (HPW) on intestinal mucositis induced by 5-fluorouracil in mice.
Human Protein-l-isoaspartate O-Methyltransferase Domain-Containing Protein 1 (PCMTD1) Associates with Cullin-RING Ligase Proteins.
BMP4 Exerts Anti-Neurogenic Effect via Inducing Id3 during Aging.
TFEB ameliorates autophagy flux disturbance induced by PBDE-47 via up-regulating autophagy-lysosome fusion.
Exosomal miRNA-181a-5p from the cells of the hair follicle dermal papilla promotes the hair follicle growth and development via the Wnt/β-catenin signaling pathway.
Induction of p27 contributes to inhibitory effect of isorhapontigenin (ISO) on malignant transformation of human urothelial cells.
Circular RNA circRNF169 functions as a miR-30c-5p sponge to promote cellular senescence.
A novel strategy for optimal component formula of anti-PRRSV from natural compounds using tandem mass tag labeled proteomic analyses.
Mussel-inspired multifunctional surface through promoting osteogenesis and inhibiting osteoclastogenesis to facilitate bone regeneration.
Impaired expression of BCAT1 relates to muscle atrophy of mouse model of sarcopenia.
VCP interaction with HMGB1 promotes hepatocellular carcinoma progression by activating the PI3K/AKT/mTOR pathway.
Conformational Constrained 4-(1-Sulfonyl-3-indol)yl-2-phenylaminopyrimidine Derivatives as New Fourth-Generation Epidermal Growth Factor Receptor Inhibitors Targeting T790M/C797S Mutations.
Human epididymis protein 4 aggravates airway inflammation and remodeling in chronic obstructive pulmonary disease.
MRNIP condensates promote DNA double-strand break sensing and end resection.
The A137R Protein of African Swine Fever Virus Inhibits Type I Interferon Production via the Autophagy-Mediated Lysosomal Degradation of TBK1.
Curcumin Derivative C66 Suppresses Pancreatic Cancer Progression through the Inhibition of JNK-Mediated Inflammation.
Mrgprb2 gene plays a role in the anaphylactoid reactions induced by Houttuynia cordata injection.
Inhibition of NOS1 promotes the interferon response of melanoma cells.
FAM64A promotes HNSCC tumorigenesis by mediating transcriptional autoregulation of FOXM1.
Vitamin C enhances the ex vivo proliferation of porcine muscle stem cells for cultured meat production.
Long-read sequencing unveils high-resolution HPV integration and its oncogenic progression in cervical cancer.
PACS-2 Ameliorates Tubular Injury by Facilitating Endoplasmic Reticulum-Mitochondria Contact and Mitophagy in Diabetic Nephropathy.
Exosomal miR-181a-2-3p derived from citreoviridin-treated hepatocytes activates hepatic stellate cells trough inducing mitochondrial calcium overload.
The RNA editing enzyme ADAR modulated by the rs1127317 genetic variant diminishes EGFR-TKIs efficiency in advanced lung adenocarcinoma.
Active Release of eCIRP via Gasdermin D Channels to Induce Inflammation in Sepsis.
Paeoniflorin inhibits pyroptosis of nucleus pulposus cells in an acidic environment and alleviates the degeneration of the intervertebral disc in rats.
A Selective Small-Molecule c-Myc Degrader Potently Regresses Lethal c-Myc Overexpressing Tumors.
Injectable self-healing hydrogel with siRNA delivery property for sustained STING silencing and enhanced therapy of intervertebral disc degeneration.
miR-455-5p regulates circadian rhythms by accelerating the degradation of Clock mRNA.
Attenuation of Activated eIF2α Signaling by ISRIB Treatment After Spinal Cord Injury Improves Locomotor Function.
Glycogen synthase kinase 3 beta inhibitor SB216763 improves Kir2.1 expression after myocardia infraction in rats.
MiR-15a-3p regulates ferroptosis via targeting glutathione peroxidase GPX4 in colorectal cancer.
CD36 promotes de novo lipogenesis in hepatocytes through INSIG2-dependent SREBP1 processing.
Scutellarein protects against cardiac hypertrophy via suppressing TRAF2/NF-κB signaling pathway.
Exogenous adenosine activates A2A adenosine receptor to inhibit RANKL-induced osteoclastogenesis via AP-1 pathway to facilitate bone repair.
miR-1290 promotes IL-8-mediated vascular endothelial cell adhesion by targeting GSK-3β.
FERM domain-containing protein 6 exerts a tumor-inhibiting role in thyroid cancer by antagonizing oncogenic YAP1.
Ginsenoside Rg3 ameliorates myocardial glucose metabolism and insulin resistance via activating the AMPK signaling pathway.
TRIM25 activates AKT/mTOR by inhibiting PTEN via K63-linked polyubiquitination in non-small cell lung cancer.
Targeting a splicing-mediated drug resistance mechanism in prostate cancer by inhibiting transcriptional regulation by PKCβ1.
YTHDF2 promotes multiple myeloma cell proliferation via STAT5A/MAP2K2/p-ERK axis.
SIRT1/mTOR pathway-mediated autophagy dysregulation promotes Pb-induced hepatic lipid accumulation in HepG2 cells.
Inhibition of Ras protein activator like 2 produces antitumor effects in gastric cancer via the suppression of YAP1 activation.
Neuroprotective Effects of Rhodiola Sacra on Transient Global Cerebral Ischemia Through Activating AMPK/Nrf2 Pathway in Rats.
Mannose-binding lectin activates the nuclear factor-κB and renal inflammation in the progression of diabetic nephropathy.
ChK1 activation induces reactive astrogliosis through CIP2A/PP2A/STAT3 pathway in Alzheimer's disease.
Nicotinamide N-methyltransferase ameliorates renal fibrosis by its metabolite 1-methylnicotinamide inhibiting the TGF-β1/Smad3 pathway.
The LncRNA RP11-301G19.1/miR-582-5p/HMGB2 axis modulates the proliferation and apoptosis of multiple myeloma cancer cells via the PI3K/AKT signalling pathway.
Map, but not EspF, induces breast epithelial cell apoptosis through ERK/DRP-1 pathway.
NOX4 stimulates ANF secretion via activation of the Sirt1/Nrf2/ATF3/4 axis in hypoxic beating rat atria.
Comparison of the effect of rotenone and 1‑methyl‑4‑phenyl‑1,2,3,6‑tetrahydropyridine on inducing chronic Parkinson's disease in mouse models.
Proteomic analysis of inhibitor of apoptosis protein‑like protein‑2 on breast cancer cell proliferation.
Nicotine promotes chronic obstructive pulmonary disease via inducing pyroptosis activation in bronchial epithelial cells.
Reversible phase separation of HSF1 is required for an acute transcriptional response during heat shock.
Early Application of Quaternized Chitin Derivatives Inhibits Hypertrophic Scar Formation.
Optimization of the saffron compound essence formula and its effect on preventing skin photoaging.
Denatured Collagen Could Increase the Autophagy Level and Inhibit Apoptosis of Fibroblasts to Help Cell Survival and Influence Wound Healing.
Inflammatory Injury and Mitophagy in the Cock Heart Induced by the Oral Administration of Hexavalent Chromium.
Chk1 Inhibition Ameliorates Alzheimer's Disease Pathogenesis and Cognitive Dysfunction Through CIP2A/PP2A Signaling.
TGM2 positively regulates myoblast differentiation via enhancing the mTOR signaling.
MicroRNA-24-3p alleviates cardiac fibrosis by suppressing cardiac fibroblasts mitophagy via downregulating PHB2.
Downregulation of the farnesoid X receptor promotes colorectal tumorigenesis by facilitating enterotoxigenic Bacteroides fragilis colonization.
E3 ubiquitin ligase Nedd4-2 exerts neuroprotective effects during endoplasmic reticulum stress.
Clinical significance of mitogen-activated protein kinase kinase kinases in hepatitis B virus -related hepatocellular carcinoma and underlying mechanism exploration.
Low-density lipoprotein receptor-related protein 8 facilitates the proliferation and invasion of non-small cell lung cancer cells by regulating the Wnt/β-catenin signaling pathway.
TRIM21 deficiency promotes cell proliferation and tumorigenesis via regulating p21 expression in ovarian cancer.
MicroRNA-130a attenuates cardiac fibrosis after myocardial infarction through TGF-β/Smad signaling by directly targeting TGF-β receptor 1.
Effects of runt-related transcription factor 2 (RUNX2) on the autophagy of rapamycin-treated osteoblasts.
Methylation recognition protein YTH N6-methyladenosine RNA binding protein 1 (YTHDF1) regulates the proliferation, migration and invasion of osteosarcoma by regulating m6A level of CCR4-NOT transcription complex subunit 7 (CNOT7).
Knockdown of mitochondrial threonyl-tRNA synthetase 2 inhibits lung adenocarcinoma cell proliferation and induces apoptosis.
The expression profile of lung long non-coding RNAs and mRNAs in a mouse model of smoke inhalation injury.
Overexpression of interleukin-10 in engineered macrophages protects endothelial cells against LPS-induced injury in vitro.
Targeting PFKL with penfluridol inhibits glycolysis and suppresses esophageal cancer tumorigenesis in an AMPK/FOXO3a/BIM-dependent manner.
Venetoclax enhances NK cell killing sensitivity of AML cells through the NKG2D/NKG2DL activation pathway.
lncRNA EDAL restricts rabies lyssavirus replication in a cell-specific and infection route-dependent manner.
Elucidation of pathological mechanism caused by human disease mutation in CaMKIIβ.
The activation of SIRT3 by dexmedetomidine mitigates limb ischemia-reperfusion-induced lung injury.
Immunomodulatory activity of aqueous extract from Crassostrea sikamea in the splenocytes of Sprague-Dawley rats.
Ubiquitin-specific protease 1 acts as an oncogene and promotes lenvatinib efficacy in hepatocellular carcinoma by stabilizing c-kit.
Cur@SF NPs alleviate Friedreich's ataxia in a mouse model through synergistic iron chelation and antioxidation.
Moderate heart rate reduction promotes cardiac regeneration through stimulation of the metabolic pattern switch.
MicroRNA-10b promotes arthritis development by disrupting CD4(+) T cell subtypes.
LncEDCH1 improves mitochondrial function to reduce muscle atrophy by interacting with SERCA2.
Overexpression of cytosolic long noncoding RNA cytb protects against pressure-overload-induced heart failure via sponging microRNA-103-3p.
YB1 associates with oncogenetic roles and poor prognosis in nasopharyngeal carcinoma.
Gene therapy of yeast NDI1 on mitochondrial complex I dysfunction in rotenone-induced Parkinson's disease models in vitro and vivo.
The fiber diameter traits of Tibetan cashmere goats are governed by the inherent differences in stress, hypoxic, and metabolic adaptations: an integrative study of proteome and transcriptome.
Karyopherin enrichment and compensation fortifies the nuclear pore complex against nucleocytoplasmic leakage.
Blocking protease-activated receptor 4 alleviates liver injury induced by brain death.
Simvastatin Downregulates Cofilin and Stathmin to Inhibit Skeletal Muscle Cells Migration.
A CFH peptide-decorated liposomal oxymatrine inactivates cancer-associated fibroblasts of hepatocellular carcinoma through epithelial-mesenchymal transition reversion.
Continuous ZnO nanoparticle exposure induces melanoma-like skin lesions in epidermal barrier dysfunction model mice through anti-apoptotic effects mediated by the oxidative stress-activated NF-κB pathway.
Inhibition of RIP3 increased ADSC viability under OGD and modified the competency of adipogenesis, angiogenesis, and inflammation regulation.
Curcuminoids Inhibit Angiogenic Behaviors of Human Umbilical Vein Endothelial Cells via Endoglin/Smad1 Signaling.
Exercise Ameliorates Atherosclerosis via Up-Regulating Serum β-Hydroxybutyrate Levels.
PTIP governs NAD(+) metabolism by regulating CD38 expression to drive macrophage inflammation.
NMDA receptor-dependent prostaglandin-endoperoxide synthase 2 induction in neurons promotes glial proliferation during brain development and injury.
Combined exposure to fine particulate matter and high glucose aggravates endothelial damage by increasing inflammation and mitophagy: the involvement of vitamin D.
HBx inhibits DNA sensing signaling pathway via ubiquitination and autophagy of cGAS.
SPIONs mediated magnetic actuation promotes nerve regeneration by inducing and maintaining repair-supportive phenotypes in Schwann cells.
Prognostic significance of SNCA and its methylation in bladder cancer.
Mesenchymal stem cells protect against ferroptosis via exosome-mediated stabilization of SLC7A11 in acute liver injury.
Fucoxanthin Attenuates Free Fatty Acid-Induced Nonalcoholic Fatty Liver Disease by Regulating Lipid Metabolism/Oxidative Stress/Inflammation via the AMPK/Nrf2/TLR4 Signaling Pathway.
Estrogen inhibits endoplasmic reticulum stress and ameliorates myocardial ischemia/reperfusion injury in rats by upregulating SERCA2a.
Remodeling of dermal adipose tissue alleviates cutaneous toxicity induced by anti-EGFR therapy.
Tumor Susceptibility Gene 101 (TSG101) Contributes to Virion Formation of Porcine Reproductive and Respiratory Syndrome Virus via Interaction with the Nucleocapsid (N) Protein along with the Early Secretory Pathway.
Ferroptosis, a new target for treatment of renal injury and fibrosis in a 5/6 nephrectomy-induced CKD rat model.
Presence of CrkI-containing microvesicles in squamous cell carcinomas could have ramifications on tumor biology and cancer therapeutics.
lncRNA HITT inhibits metastasis by attenuating Rab5-mediated endocytosis in lung adenocarcinoma.
Exosome-derived circTRPS1 promotes malignant phenotype and CD8+ T cell exhaustion in bladder cancer microenvironments.
Heat Stress Impairs Maternal Endometrial Integrity and Results in Embryo Implantation Failure by Regulating Transport-Related Gene Expression in Tongcheng Pigs.
SLC4A4 promotes prostate cancer progression in vivo and in vitro via AKT-mediated signalling pathway.
PINK1/TAX1BP1-directed mitophagy attenuates vascular endothelial injury induced by copper oxide nanoparticles.
Claudin1 decrease induced by 1,25-dihydroxy-vitamin D3 potentiates gefitinib resistance therapy through inhibiting AKT activation-mediated cancer stem-like properties in NSCLC cells.
Duck plague virus UL41 protein inhibits RIG-I/MDA5-mediated duck IFN-β production via mRNA degradation activity.
Dynamic control of chromatin-associated m(6)A methylation regulates nascent RNA synthesis.
Synthetic mRNA-based gene therapy for glioblastoma: TRAIL-mRNA synergistically enhances PTEN-mRNA-based therapy.
Comprehensive analysis of FKBP4/NR3C1/TMEM173 signaling pathway in triple-negative breast cancer cell and dendritic cell among tumor microenvironment.
Intracranial delivery of synthetic mRNA to suppress glioblastoma.
A Distinct Metabolically Defined Central Nucleus Circuit Bidirectionally Controls Anxiety-Related Behaviors.
IGF-1 Signaling Regulates Mitochondrial Remodeling during Myogenic Differentiation.
Daidzein suppresses TGF-β1-induced cardiac fibroblast activation via the TGF-β1/SMAD2/3 signaling pathway.
DL0805-1, a novel Rho-kinase inhibitor, attenuates lung injury and vasculopathy in a rat model of monocrotaline-induced pulmonary hypertension.
EBV Infection in Epithelial Malignancies Induces Resistance to Antitumor Natural Killer Cells via F3-Mediated Platelet Aggregation.
RAD51 is essential for spermatogenesis and male fertility in mice.
Salvia miltiorrhiza polysaccharides alleviates florfenicol induced kidney injury in chicks via inhibiting oxidative stress and apoptosis.
TMEM106B deficiency impairs cerebellar myelination and synaptic integrity with Purkinje cell loss.
S100A16 promotes acute kidney injury by activating HRD1-induced ubiquitination and degradation of GSK3β and CK1α.
Antagonistic L1 Adhesion Molecule Mimetic Compounds Inhibit Glioblastoma Cell Migration In Vitro.
2-Fluorofucose Attenuates Hydrogen Peroxide-Induced Oxidative Stress in HepG2 Cells via Nrf2/keap1 and NF-κB Signaling Pathways.
Environmental cadmium impairs blood-testis barrier via activating HRI-responsive mitochondrial stress in mice.
Targeting macrophage TFEB-14-3-3 epsilon Interface by naringenin inhibits abdominal aortic aneurysm.
Vitamin D receptor regulates proliferation and differentiation of thyroid carcinoma via the E-cadherin-β-catenin complex.
Lipoxin A(4) and its analog attenuate high fat diet-induced atherosclerosis via Keap1/Nrf2 pathway.
Isoxanthohumol, a component of Sophora flavescens, promotes the activation of the NLRP3 inflammasome and induces idiosyncratic hepatotoxicity.
C3/C3aR inhibition alleviates GMH-IVH-induced hydrocephalus by preventing microglia-astrocyte interactions in neonatal rats.
Rescuing ischemic stroke by biomimetic nanovesicles through accelerated thrombolysis and sequential ischemia-reperfusion protection.
ADAR1 inhibits adipogenesis and obesity by interacting with Dicer to promote the maturation of miR-155-5P.
Upregulation of BRD7 protects podocytes against high glucose-induced apoptosis by enhancing Nrf2 in a GSK-3β-dependent manner.
Piezo1 and IFT88 synergistically regulate mandibular condylar chondrocyte differentiation under cyclic tensile strain.
Deactivation of AKT/GSK-3β-mediated Wnt/β-catenin pathway by silencing of KIF26B weakens the malignant behaviors of non-small cell lung cancer.
CD146 as a promising therapeutic target for retinal and choroidal neovascularization diseases.
ADAR1 masks the cancer immunotherapeutic promise of ZBP1-driven necroptosis.
Butyrate supplementation regulates expression of chromosome segregation 1‑like protein to reverse the genetic distortion caused by p53 mutations in colorectal cancer.
Astaxanthin attenuates contrast-induced acute kidney injury in rats via ROS/NLRP3 inflammasome.
Suppression of ATG4B by copper inhibits autophagy and involves in Mallory body formation.
Pyrimethamine inhibits cell growth by inducing cell senescence and boosting CD8(+) T-cell mediated cytotoxicity in colorectal cancer.
Atorvastatin reduces IOP in ocular hypertension in vivo and suppresses ECM in trabecular meshwork perhaps via FGD4.
Schwann cell‑like cells derived from human amniotic mesenchymal stem cells promote sciatic nerve repair through an exosome‑induced SOX2/FN1 pathway in vitro.
ER Stress is Involved in Mast Cells Degranulation via IRE1α/miR-125/Lyn Pathway in an Experimental Intracerebral Hemorrhage Mouse Model.
LINC02154 promotes the proliferation and metastasis of hepatocellular carcinoma by enhancing SPC24 promoter activity and activating the PI3K-AKT signaling pathway.
MiR-15p-5p Mediates the Coordination of ICAM-1 and FAK to Promote Endothelial Cell Proliferation and Migration.
Transcription Factor Specificity Protein 1 Regulates Inflammation and Fibrin Deposition in Nasal Polyps Via the Regulation of microRNA-125b and the Wnt/β-catenin Signaling Pathway.
GPCR-mediated EGFR transactivation ameliorates skin toxicities induced by afatinib.
Asiatic acid alleviates ischemic myocardial injury in mice by modulating mitophagy- and glycophagy-based energy metabolism.
Ginkgo Biloba Extract Ameliorates Scopolamine-induced Memory Deficits via Rescuing Synaptic Damage.
Astrocytic Gap Junctions Contribute to Aberrant Neuronal Synchronization in a Mouse Model of MeCP2 Duplication Syndrome.
Inhibition of FAM83D displays antitumor effects in glioblastoma via down-regulation of the AKT/Wnt/β-catenin pathway.
Naringin alleviates acetaminophen-induced acute liver injury by activating Nrf2 via CHAC2 upregulation.
Identification and characterization of a special type of subnuclear structure: AGGF1-coated paraspeckles.
Mitophagy induced by UMI-77 preserves mitochondrial fitness in renal tubular epithelial cells and alleviates renal fibrosis.
Sclareol ameliorates hyperglycemia-induced renal injury through inhibiting the MAPK/NF-κB signaling pathway.
MiR-153 downregulation alleviates PTSD-like behaviors and reduces cell apoptosis by upregulating the Sigma-1 receptor in the hippocampus of rats exposed to single-prolonged stress.
Early environmental enrichment for autism spectrum disorder Fmr1 mice models has positive behavioral and molecular effects.
TP53-inducible putative long noncoding RNAs encode functional polypeptides that suppress cell proliferation.
Berberine inhibits IFN-γ signaling pathway in DSS-induced ulcerative colitis.
Loss of mitochondrial ATPase ATAD3A contributes to nonalcoholic fatty liver disease through accumulation of lipids and damaged mitochondria.
Myeloid-derived suppressor cells promote tumor growth and sorafenib resistance by inducing FGF1 upregulation and fibrosis.
A possible new activator of PI3K-Huayu Qutan Recipe alleviates mitochondrial apoptosis in obesity rats with acute myocardial infarction.
RFTN1 facilitates gastric cancer progression by modulating AKT/p38 signaling pathways.
Action of the Nrf2/ARE signaling pathway on oxidative stress in choroid plexus epithelial cells following lanthanum chloride treatment.
hsa_circ_0000523/miR-let-7b/METTL3 axis regulates proliferation, apoptosis and metastasis in the HCT116 human colorectal cancer cell line.
AMG487 inhibits PRRSV replication and ameliorates lung injury in pig lung xenografts by down-regulating the expression of ANXA2.
Activation of CXCL13/CXCR5 axis aggravates experimental autoimmune cystitis and interstitial cystitis/bladder pain syndrome.
The relationship between epigenetic age and the hallmarks of aging in human cells.
FAIM regulates autophagy through glutaminolysis in lung adenocarcinoma.
Progenitor cells derived from gene-engineered human induced pluripotent stem cells as synthetic cancer cell alternatives for in vitro pharmacology.
Ror2-mediated cholesterol accumulation regulates autophagic activity within BCG-infected macrophages.
Ligustrazine alleviates psoriasis-like inflammation through inhibiting TRAF6/c-JUN/NFκB signaling pathway in keratinocyte.
Dexmedetomidine attenuates perioperative neurocognitive disorders by suppressing hippocampal neuroinflammation and HMGB1/RAGE/NF-κB signaling pathway.
Obeticholic acid inhibits hepatic fatty acid uptake independent of FXR in mouse.
Novel RARS2 Variants: Updating the Diagnosis and Pathogenesis of Pontocerebellar Hypoplasia Type 6.
ZNF677 suppresses renal cell carcinoma progression through N6-methyladenosine and transcriptional repression of CDKN3.
Discovery of oridonin as a novel agonist for BRS-3.
Beneficial effects of aloperine on inflammation and oxidative stress by suppressing necroptosis in lipopolysaccharide-induced acute lung injury mouse model.
Nanoparticle delivery of miR-21-3p sensitizes melanoma to anti-PD-1 immunotherapy by promoting ferroptosis.
Bioinformatics analysis combined with experiments to verify potential autophagy genes in wound healing.
Sorafenib inhibits LPS-induced inflammation by regulating Lyn-MAPK-NF-kB/AP-1 pathway and TLR4 expression.
Novel Sphingosine Kinase 1 Inhibitor Suppresses Growth of Solid Tumor and Inhibits the Lung Metastasis of Triple-Negative Breast Cancer.
A novel ALG10/TGF-β positive regulatory loop contributes to the stemness of colorectal cancer.
Novel Thermosensitive Hydrogel Promotes Spinal Cord Repair by Regulating Mitochondrial Function.
Occlusal Disharmony-A Potential Factor Promoting Depression in a Rat Model.
Adrenomedullin Improves Cardiac Remodeling and Function in Obese Rats with Hypertension.
Synthesis and structure-activity relationship study of a potent MHO7 analogue as potential anti-triple negative breast cancer agent.
A pH-Dependent rhodamine fluorophore with antiproliferative activity of bladder cancer in Vitro/Vivo and apoptosis mechanism.
SGK1 in Schwann cells is a potential molecular switch involved in axonal and glial regeneration during peripheral nerve injury.
Insulin alleviates LPS-induced ARDS via inhibiting CUL4B-mediated proteasomal degradation and restoring expression level of Na,K-ATPase α1 subunit through elevating HCF-1.
Cumulative autophagy insufficiency in mice leads to progression of β-cell failure.
STING activation promotes inflammatory response and delays skin wound healing in diabetic mice.
MicroRNA-223-3p promotes pyroptosis of cardiomyocyte and release of inflammasome factors via downregulating the expression level of SPI1 (PU.1).
Upregulation of CCT3 predicts poor prognosis and promotes cell proliferation via inhibition of ferroptosis and activation of AKT signaling in lung adenocarcinoma.
CircEZH2/miR-133b/IGF2BP2 aggravates colorectal cancer progression via enhancing the stability of m(6)A-modified CREB1 mRNA.
Trans-cellular tunnels induced by the fungal pathogen Candida albicans facilitate invasion through successive epithelial cells without host damage.
Preparation of Recombinant Human Collagen III Protein Hydrogels with Sustained Release of Extracellular Vesicles for Skin Wound Healing.
A Class I HDAC Inhibitor Rescues Synaptic Damage and Neuron Loss in APP-Transfected Cells and APP/PS1 Mice through the GRIP1/AMPA Pathway.
Gut Microbiota Mediates the Protective Effects of Traditional Chinese Medicine Formula Qiong-Yu-Gao against Cisplatin-Induced Acute Kidney Injury.
Khasianine ameliorates psoriasis-like skin inflammation and represses TNF-α/NF-κB axis mediated transactivation of IL-17A and IL-33 in keratinocytes.
A volatile from the skin microbiota of flavivirus-infected hosts promotes mosquito attractiveness.
Astrocyte reactivation in medial prefrontal cortex contributes to obesity-promoted depressive-like behaviors.
The 22q11.2 region regulates presynaptic gene-products linked to schizophrenia.
Hydroxychloroquine alleviates renal interstitial fibrosis by inhibiting the PI3K/Akt signaling pathway.
An N-glycoproteomic site-mapping analysis reveals glycoprotein alterations in esophageal squamous cell carcinoma.
LncRNA PEG11as silencing sponges miR-874-3p to alleviate cerebral ischemia stroke via regulating autophagy in vivo and in vitro.
G Protein Subunit β1 Facilitates Influenza A Virus Replication by Promoting the Nuclear Import of PB2.
Establishment of a Novel Cell Surface Display Platform Based on Natural "Chitosan Beads" of Yeast Spores.
Pathogenic SLC25A26 variants impair SAH transport activity causing mitochondrial disease.
Abnormal activation of Yap/Taz contributes to the pathogenesis of tuberous sclerosis complex.
Upregulated GATA3/miR205-5p Axis Inhibits MFNG Transcription and Reduces the Malignancy of Triple-Negative Breast Cancer.
Treadmill training improves respiratory function in rats after spinal cord injury by inhibiting the HMGB1/TLR-4/NF-κB signaling pathway.
Oxidative stress from DGAT1 oncoprotein inhibition in melanoma suppresses tumor growth when ROS defenses are also breached.
(-)-α-Bisabolol Alleviates Atopic Dermatitis by Inhibiting MAPK and NF-κB Signaling in Mast Cell.
Adlay Seed (Coix lacryma-jobi L. var. Ma-yuen Stapf.) Ethanolic Extract Fractions and Subfractions Induce Cell Cycle Arrest and Apoptosis in Human Breast and Cervical Cancer Cell Lines.
Apelin alleviated neuroinflammation and promoted endogenous neural stem cell proliferation and differentiation after spinal cord injury in rats.
Complement C3a activates astrocytes to promote medulloblastoma progression through TNF-α.
The PRMT5-LSD1 axis confers Slug dual transcriptional activities and promotes breast cancer progression.
LINC00094/miR-19a-3p/CYP19A1 axis affects the sensitivity of ER positive breast cancer cells to Letrozole through EMT pathway.
Cryopreservation Competence of Chicken Oocytes as a Model of Endangered Wild Birds: Effects of Storage Time and Temperature on the Ovarian Follicle Survival.
Enhanced autophagy promotes radiosensitivity by mediating Sirt1 downregulation in RM-1 prostate cancer cells.
The mechanism of the WNT5A and FZD4 receptor mediated WNT/β-catenin pathway in the degeneration of ALS spinal cord motor neurons.
Grpel2 alleviates myocardial ischemia/reperfusion injury by inhibiting MCU-mediated mitochondrial calcium overload.
Protocol to induce and assess cGAS-STING pathway activation in vitro.
Isolation of five different primary cell types from a single sample of human skin.
Diminished Rbfox1 increases vascular constriction by dynamically regulating alternative splicing of CaV1.2 calcium channel in hypertension.
A long-term anti-inflammation markedly alleviated high-fat diet-induced obesity by repeated administrations of overexpressing IL10 human umbilical cord-derived mesenchymal stromal cells.
Coxiella burnetii Plasmid Effector B Promotes LC3-II Accumulation and Contributes To Bacterial Virulence in a SCID Mouse Model.
Redirecting anti-Vaccinia virus T cell immunity for cancer treatment by AAV-mediated delivery of the VV B8R gene.
A novel phosphodiesterase 9A inhibitor LW33 protects against ischemic stroke through the cGMP/PKG/CREB pathway.
Neurotoxicity and gene expression alterations in zebrafish larvae in response to manganese exposure.
FAM98A promotes resistance to 5-fluorouracil in colorectal cancer by suppressing ferroptosis.
Elevated latent transforming growth factor beta binding protein 2 in endometriosis promotes endometrial stromal cell invasion and proliferation via the NF-kB signaling pathway.
TRIM62 silencing represses the proliferation and invasion and increases the chemosensitivity of hepatocellular carcinoma cells by affecting the NF-κB pathway.
Deubiquitinating enzyme PSMD14 facilitates gastric carcinogenesis through stabilizing PTBP1.
Upregulation of hepatic CD36 via glucocorticoid receptor activation contributes to dexamethasone-induced liver lipid metabolism disorder in mice.
JNK and Jag1/Notch2 co-regulate CXCL16 to facilitate cypermethrin-induced kidney damage.
The IL-33/ST2 Axis Promotes Primary Sjögren's Syndrome by Enhancing Salivary Epithelial Cell Activation and Type 1 Immune Response.
Exosomal mitochondrial tRNAs and miRNAs as potential predictors of inflammation in renal proximal tubular epithelial cells.
TAZ ameliorates the microglia-mediated inflammatory response via the Nrf2-ROS-NF-κB pathway.
Thrombospondin-2 acts as a bridge between tumor extracellular matrix and immune infiltration in pancreatic and stomach adenocarcinomas: an integrative pan-cancer analysis.
Dopamine-derived nanoparticles for the protection of irradiation-induced intestinal injury by maintaining intestinal homeostasis.
RING finger 138 deregulation distorts NF-кB signaling and facilities colitis switch to aggressive malignancy.
Fast detection, a precise and sensitive diagnostic agent for breast cancer.
A Cross-Tissue Investigation of Molecular Targets and Physiological Functions of Nsun6 Using Knockout Mice.
The effect of Ma-Xin-Gan-Shi decoction on asthma exacerbated by respiratory syncytial virus through regulating TRPV1 channel.
Phenazine derivatives attenuate the stemness of breast cancer cells through triggering ferroptosis.
Acute cold stress induces transient MuRF1 upregulation in the skeletal muscle of zebrafish.
CUX1 promotes epithelial-mesenchymal transition (EMT) in renal fibrosis of UUO model by targeting MMP7.
ITRAQ-based quantitative proteomic analysis reveals that VPS35 promotes the expression of MCM2-7 genes in HeLa cells.
Platelet-Membrane-Encapsulated Carvedilol with Improved Targeting Ability for Relieving Myocardial Ischemia-Reperfusion Injury.
Chronic clomipramine treatment increases hippocampal volume in rats exposed to chronic unpredictable mild stress.
Selenium Status in Diet Affects Nephrotoxicity Induced by Cisplatin in Mice.
Identification of differentially expressed miRNAs derived from serum exosomes associated with gastric cancer by microarray analysis.
IL-6 promotes chemoresistance via upregulating CD36 mediated fatty acids uptake in acute myeloid leukemia.
Transcriptomics analysis and benchmark concentration estimating-based in vitro test with IOSE80 cells to unveil the mode of action for female reproductive toxicity of bisphenol A at human-relevant levels.
Pivotal roles of ELONGATED HYPOCOTYL5 in regulation of plant development and fruit metabolism in tomato.
Ppp4r3a deficiency leads to depression-like behaviors in mice by modulating the synthesis of synaptic proteins.
Exogenous Otx2 protects midbrain dopaminergic neurons from MPP(+) by interacting with ATP5a1 and promoting ATP synthesis.
SNAT2/SLC38A2 Confers the Stemness of Gastric Cancer Cells via Regulating Glutamine Level.
Attenuation by HSP90 inhibitors of EGF-elicited migration of osteoblasts: involvement of p44/p42 MAP kinase.
Inhibition of nuclear deacetylase Sirtuin-1 induces mitochondrial acetylation and calcium overload leading to cell death.
Pharmacological activation of estrogenic receptor G protein-coupled receptor 30 attenuates angiotensin II-induced atrial fibrosis in ovariectomized mice by modulating TGF-β1/smad pathway.
Comprehensive analysis of the expression and prognosis of YPEL family members in clear cell renal cell cancer.
Ophiopogonin D'-induced mitophagy and mitochondrial damage are associated with dysregulation of the PINK1/Parkin signaling pathway in AC16 cells.
In utero hypoxia attenuated acetylcholine-mediated vasodilatation via CHRM3/p-NOS3 in fetal sheep MCA: role of ROS/ERK1/2.
FOXM1 Promotes Malignant Proliferation of Esophageal Squamous Cell Carcinoma Through Transcriptional Activating CDC6.
HAO1-mediated oxalate metabolism promotes lung pre-metastatic niche formation by inducing neutrophil extracellular traps.
2-undecanone protects against fine particles-induced heart inflammation via modulating Nrf2/HO-1 and NF-κB pathways.
MicroRNA profiling reveals miR-145-5p inhibits goat myoblast differentiation by targeting the coding domain sequence of USP13.
Trilobatin promotes angiogenesis after cerebral ischemia-reperfusion injury via SIRT7/VEGFA signaling pathway in rats.
Retraction Note: Long noncoding RNA LINC00460 promotes the progression of cervical cancer via regulation of the miR-361-3p/Gli1 axis.
Integrated multicomponent analysis based on UHPLC-Q-Exactive Orbitrap-MS and network pharmacology to elucidate the potential mechanism of Baoyuan decoction against idiopathic pulmonary fibrosis.
Iron-regulated assembly of the cytosolic iron-sulfur cluster biogenesis machinery.
NUMB facilitates autophagy initiation through targeting SCF(β-TrCP2) complex.
Clusterin protects against Cr(VI)-induced oxidative stress-associated hepatotoxicity by mediating the Akt-Keap1-Nrf2 signaling pathway.
Hypothermia preconditioning improves cardiac contractility after cardiopulmonary resuscitation through AMPK-activated mitophagy.
Cancer germline antigen gene MAGEB2 promotes cell invasion and correlates with immune microenvironment and immunotherapeutic efficiency in laryngeal cancer.
Germacrone induces caspase-3/GSDME activation and enhances ROS production, causing HepG2 pyroptosis.
High expression of 14-3-3ơ indicates poor prognosis and progression of lung adenocarcinoma.
Selenium alleviates cadmium-induced aging via mitochondrial quality control in the livers of sheep.
Lysyl oxidase-like 2 inhibitor rescues D-galactose-induced skeletal muscle fibrosis.
Inhibition of Cpt1a alleviates oxidative stress-induced chondrocyte senescence via regulating mitochondrial dysfunction and activating mitophagy.
S1PR2/RhoA/ROCK1 pathway promotes inflammatory bowel disease by inducing intestinal vascular endothelial barrier damage and M1 macrophage polarization.
Mitochondrial and glucose metabolic dysfunctions in granulosa cells induce impaired oocytes of polycystic ovary syndrome through Sirtuin 3.
Newcastle disease virus degrades SIRT3 via PINK1-PRKN-dependent mitophagy to reprogram energy metabolism in infected cells.
DEPTOR exacerbates bone-fat imbalance in osteoporosis by transcriptionally modulating BMSC differentiation.
Endogenous and exogenous hydrogen sulfide modulates urothelial bladder carcinoma development in human cell lines.
Berberine exerts protective effects on cardiac senescence by regulating the Klotho/SIRT1 signaling pathway.
Curcumin exerts chondroprotective effects against osteoarthritis by promoting AMPK/PINK1/Parkin-mediated mitophagy.
KGF-2 Regulates STAP-2-Mediated Signal Transducer and Activator of Transcription 3 Signaling and Reduces Skin Scar Formation.
BUB1 predicts poor prognosis and immune status in liver hepatocellular carcinoma.
Design, synthesis and biological evaluation of (R)-5-methylpyrrolidin-2-ones as p300 bromodomain inhibitors with Anti-Tumor activities in multiple tumor lines.
SHMT2 promotes the tumorigenesis of renal cell carcinoma by regulating the m6A modification of PPAT.
GNAQ T96S mutation abrogates the ability of wild-type GNAQ to induce apoptosis by phosphorylating annexin A2 in natural killer/T cell lymphoma.
Homosalate boosts the release of tumour-derived extracellular vesicles with protection against anchorage-loss property.
IQGAP1 is positively correlated with PD-L1 and regulates its expression via mediating STAT proteins phosphorylation.
Trans-anethole ameliorates LPS-induced inflammation via suppression of TLR4/NF-κB pathway in IEC-6 cells.
Asiaticoside ameliorates osteoarthritis progression through activation of Nrf2/HO-1 and inhibition of the NF-κB pathway.
Recombinant humanized IgG1 maintain liver triglyceride homeostasis through Arylacetamide deacetylase in ApoE(-/-) mice.
Asperuloside inhibited epithelial-mesenchymal transition in colitis associated cancer via activation of vitamin D receptor.
Palbociclib regulates the expression of dihydrofolate reductase and the cell cycle to inhibit t (11;14) multiple myeloma.
Secretion of the disulfide bond generating catalyst QSOX1 from pancreatic tumor cells into the extracellular matrix: association with extracellular vesicles and matrix proteins.
Combination of midostaurin and ATRA exerts dose-dependent dual effects on acute myeloid leukemia cells with wild type FLT3.
H3K36me2 methyltransferase NSD2 orchestrates epigenetic reprogramming during spermatogenesis.
Eleutheroside E supplementation prevents radiation-induced cognitive impairment and activates PKA signaling via gut microbiota.
Human Platelet Lysate Induces Antiviral Responses against Parechovirus A3.
Low expression of PRDM5 predicts poor prognosis of esophageal squamous cell carcinoma.
Protein nanoparticle-induced osmotic pressure gradients modify pulmonary edema through hyperpermeability in acute respiratory distress syndrome.
Mitochondrial fission induces immunoescape in solid tumors through decreasing MHC-I surface expression.
Cholecystokinin and glucagon-like peptide-1 analogues regulate intestinal tight junction, inflammation, dopaminergic neurons and α-synuclein accumulation in the colon of two Parkinson's disease mouse models.
Spatiotemporal regulation of insulin signaling by liquid-liquid phase separation.
Photoaffinity Labeling-Based Chemoproteomic Strategy Reveals RBBP4 as a Cellular Target of Protopanaxadiol against Colorectal Cancer Cells.
Peptide PDHPS1 Inhibits Ovarian Cancer Growth through Disrupting YAP Signaling.
Expression of lncRNA APF in Peripheral Blood of Patients with Acute Myocardial Infarction Caused by Coronary Heart Disease and its Clinical Significance.
Identification of mutant p53-specific proteins interaction network using TurboID-based proximity labeling.
CDC-like kinase 4 deficiency contributes to pathological cardiac hypertrophy by modulating NEXN phosphorylation.
Mitochondrial proteostasis stress in muscle drives a long-range protective response to alleviate dietary obesity independently of ATF4.
PTPRO knockdown protects against inflammation in hemorrhage shock-induced lung injury involving the NF-κB signaling pathway.
Discovery of Novel Phosphoinositide-3-Kinase α Inhibitors with High Selectivity, Excellent Bioavailability, and Long-Acting Efficacy for Gastric Cancer.
ISX-9 potentiates CaMKIIδ-mediated BMAL1 activation to enhance circadian amplitude.
Peptidome analysis of human intrauterine adhesion tissues and the identification of antifibrotic peptide.
Microtubule associated protein 4 phosphorylation-induced epithelial-to-mesenchymal transition of podocyte leads to proteinuria in diabetic nephropathy.
Bone marrow mesenchymal stem cells inhibit hepatic fibrosis via the AABR07028795.2/rno-miR-667-5p axis.
GCN5/KAT2A contributes to axon growth and neurogenesis.
Effects of Artemisinin on Escherichia coli-Induced Mastitis in Bovine Mammary Epithelial Cells and Mice.
Inhibition of CSPG receptor PTPσ promotes migration of newly born neuroblasts, axonal sprouting, and recovery from stroke.
Curcumin Induces Apoptosis of Chemoresistant Lung Cancer Cells via ROS-Regulated p38 MAPK Phosphorylation.
Genomic signature of MTOR could be an immunogenicity marker in human colorectal cancer.
Wharton's jelly mesenchymal stem cell-derived small extracellular vesicles as natural nanoparticles to attenuate cartilage injury via microRNA regulation.
Albumin-induced premature senescence in human renal proximal tubular cells and its relationship with intercellular fibrosis.
Increased cytochrome C threonine 50 phosphorylation in aging heart as a novel defensive signaling against hypoxia/reoxygenation induced apoptosis.
CysLT(2)R Antagonist HAMI 3379 Ameliorates Post-Stroke Depression through NLRP3 Inflammasome/Pyroptosis Pathway in Gerbils.
CTNND1 variants cause familial exudative vitreoretinopathy through the Wnt/cadherin axis.
ARHGEF37 overexpression promotes extravasation and metastasis of hepatocellular carcinoma via directly activating Cdc42.
NCAPG promotes the proliferation of hepatocellular carcinoma through the CKII-dependent regulation of PTEN.
TGFβ1-transfected tendon stem cells promote tendon fibrosis.
Overexpression of NNMT in Glioma Aggravates Tumor Cell Progression: An Emerging Therapeutic Target.
Self-Assembly of a Multifunction DNA Tetrahedron for Effective Delivery of Aptamer PL1 and Pcsk9 siRNA Potentiate Immune Checkpoint Therapy for Colorectal Cancer.
Transcriptomic profiling revealed the role of apigenin-4'-O-α-L-rhamnoside in inhibiting the activation of rheumatoid arthritis fibroblast-like synoviocytes via MAPK signaling pathway.
An integrated network pharmacology and cell metabolomics approach to reveal the role of rhein, a novel PPARα agonist, against renal fibrosis by activating the PPARα-CPT1A axis.
Magnetic hyperthermia induces effective and genuine immunogenic tumor cell death with respect to exogenous heating.
Single-cell multiomics analysis reveals regulatory programs in clear cell renal cell carcinoma.
N-glycosylation of GDF15 abolishes its inhibitory effect on EGFR in AR inhibitor-resistant prostate cancer cells.
Viral evasion of PKR restriction by reprogramming cellular stress granules.
FL-DTD: an integrated pipeline to predict the drug interacting targets by feedback loop-based network analysis.
Glycyrrhizic Acid Attenuates Pulmonary Fibrosis of Silicosis by Inhibiting the Interaction between HMGB1 and BRG1 through PI3K/Akt/mTOR Pathway.
ZIP14 is involved in iron deposition and triggers ferroptosis in diabetic nephropathy.
Hepatocyte growth factor derived from senescent cells attenuates cell competition-induced apical elimination of oncogenic cells.
A pan-cancer analysis of thioredoxin-interacting protein as an immunological and prognostic biomarker.
Identification of benzamides derivatives of norfloxacin as promising microRNA-21 inhibitors via repressing its transcription.
Deficiency of NARFL increases transcription of NADPH oxidases and ROS production impairing the function of endothelial cells.
The Chinese medicine Fufang Zhenzhu Tiaozhi capsule protects against atherosclerosis by suppressing EndMT via modulating Akt1/β-catenin signaling pathway.
The SARS-CoV-2 protein NSP2 impairs the silencing capacity of the human 4EHP-GIGYF2 complex.
The role of ciliopathy-associated type 3 adenylyl cyclase in infanticidal behavior in virgin adult male mice.
GCN5 participates in KLF4-VEGFA feedback to promote endometrial angiogenesis.
Sex-Based Differences in Human Neutrophil Chemorepulsion.
YTHDF3 Facilitates eIF2AK2 and eIF3A Recruitment on mRNAs to Regulate Translational Processes in Oxaliplatin-Resistant Colorectal Cancer.
CCL20/CCR6 axis mediates macrophages to promote proliferation and migration of ESCs by blocking autophagic flux in endometriosis.
RBM47 inhibits hepatocellular carcinoma progression by targeting UPF1 as a DNA/RNA regulator.
Chronic stress-induced depression requires the recruitment of peripheral Th17 cells into the brain.
ZEB2/TWIST1/PRMT5/NuRD Multicomplex Contributes to the Epigenetic Regulation of EMT and Metastasis in Colorectal Carcinoma.
Histone demethylase JMJD3 downregulation protects against aberrant force-induced osteoarthritis through epigenetic control of NR4A1.
Circ_0000181 regulates miR-667-5p/NLRC4 axis to promote pyroptosis progression in diabetic nephropathy.
FUBP3 Degrades the Porcine Epidemic Diarrhea Virus Nucleocapsid Protein and Induces the Production of Type I Interferon.
Transient neuroinflammation following surgery contributes to long-lasting cognitive decline in elderly rats via dysfunction of synaptic NMDA receptor.
Overexpressed COL3A1 has prognostic value in human esophageal squamous cell carcinoma and promotes the aggressiveness of esophageal squamous cell carcinoma by activating the NF-κB pathway.
Inhibition of SIRT2 promotes APP acetylation and ameliorates cognitive impairment in APP/PS1 transgenic mice.
BMSC-derived exosomes protect against kidney injury through regulating klotho in 5/6 nephrectomy rats.
Caffeine Decreases Hepcidin Expression to Alleviate Aberrant Iron Metabolism under Inflammation by Regulating the IL-6/STAT3 Pathway.
TFCP2, a binding protein of ATF3, promotes the progression of glioma by activating the synthesis of serine.
Fenbendazole and its synthetic analog interfere with HeLa cells' proliferation and energy metabolism via inducing oxidative stress and modulating MEK3/6-p38-MAPK pathway.
Belumosudil, ROCK2-specific inhibitor, alleviates cardiac fibrosis by inhibiting cardiac fibroblasts activation.
DOCK2 contributes to pulmonary fibrosis by promoting lung fibroblast to myofibroblast transition.
Combined exposure of lead and high-fat diet enhanced cognitive decline via interacting with CREB-BDNF signaling in male rats.
Ambient fine particulate matter exposure disrupts placental autophagy and fetal development in gestational mice.
HMGB1-NLRP3-P2X7R pathway participates in PM(2.5)-induced hippocampal neuron impairment by regulating microglia activation.
Kir2.1 channel regulates macrophage polarization via the Ca2+/CaMK II/ERK/NF-κB signaling pathway.
Spinal Cord Stimulation Alleviates Neuropathic Pain by Attenuating Microglial Activation via Reducing Colony-Stimulating Factor 1 Levels in the Spinal Cord in a Rat Model of Chronic Constriction Injury.
miR-1307-5p suppresses proliferation and tumorigenesis of bladder cancer via targeting MDM4 and the Hippo signaling pathway.
Interleukin 7 inhibit autophagy via P53 regulated AMPK/mTOR signaling pathway in non-small cell lung cancer.
Molecular Subgroups of Intrahepatic Cholangiocarcinoma Discovered by Single-Cell RNA Sequencing-Assisted Multiomics Analysis.
Extracts of Poria cocos improve functional dyspepsia via regulating brain-gut peptides, immunity and repairing of gastrointestinal mucosa.
Protective effects of Huang-Lian-Jie-Du Decoction on diabetic nephropathy through regulating AGEs/RAGE/Akt/Nrf2 pathway and metabolic profiling in db/db mice.
Dysmyelination by Oligodendrocyte-Specific Ablation of Ninj2 Contributes to Depressive-Like Behaviors.
Ciliary Type III Adenylyl Cyclase in the VMH Is Crucial for High-Fat Diet-Induced Obesity Mediated by Autophagy.
H. pylori CagA activates the NLRP3 inflammasome to promote gastric cancer cell migration and invasion.
Increased m6A-RNA methylation and FTO suppression is associated with myocardial inflammation and dysfunction during endotoxemia in mice.
PPARα agonist fenofibrate relieves acquired resistance to gefitinib in non-small cell lung cancer by promoting apoptosis via PPARα/AMPK/AKT/FoxO1 pathway.
Autophagy regulates the cancer stem cell phenotype of head and neck squamous cell carcinoma through the noncanonical FOXO3/SOX2 axis.
Smoking-associated upregulation of CBX3 suppresses ARHGAP24 expression to activate Rac1 signaling and promote tumor progression in lung adenocarcinoma.
Disruption of the mouse Bmal1 locus promotes heterotopic ossification with aging via TGF-beta/BMP signaling.
CD93 a potential player in cytotrophoblast and endothelial cell migration.
Circular RNA circUSP13 sponges miR-29c to promote differentiation and inhibit apoptosis of goat myoblasts by targeting IGF1.
CircRNA_01477 influences axonal growth via regulating miR-3075/FosB/Stat3 axis.
Selective activation of cannabinoid receptor-2 reduces white matter injury via PERK signaling in a rat model of traumatic brain injury.
Inhibition of progesterone receptor membrane component-1 exacerbates neonatal hypoxic-ischemic cerebral damage in male mice.
Novel mutations of TYK2 leading to divergent clinical phenotypes.
Glycocalyx is critical for blood-brain barrier integrity by suppressing caveolin1-dependent endothelial transcytosis following ischemic stroke.
Bcl-2 hijacks the arsenic trioxide resistance in SH-SY5Y cells.
IGF2BP3 promotes cell metastasis and is associated with poor patient survival in nasopharyngeal carcinoma.
Caveolin-1 negatively regulates inflammation and fibrosis in silicosis.
Hepatitis B virus X mediates podocyte pyroptosis by regulating the ROS/NLRP3 signaling pathway in hepatitis B virus-associated glomerulonephritis.
Jolkinolide B alleviates renal fibrosis via anti-inflammation and inhibition of epithelial-mesenchymal transition in unilateral ureteral obstruction mice.
Inhibition of DNA methyltransferase aberrations reinstates antioxidant aging suppressors and ameliorates renal aging.
Morphological changes of macrophages and their potential contribution to tendon healing.
MICAL1 inhibits colorectal cancer cell migration and proliferation by regulating the EGR1/β-catenin signaling pathway.
Dictamnine, a novel c-Met inhibitor, suppresses the proliferation of lung cancer cells by downregulating the PI3K/AKT/mTOR and MAPK signaling pathways.
Maresin 1 protects against lipopolysaccharide/d-galactosamine-induced acute liver injury by inhibiting macrophage pyroptosis and inflammatory response.
Is platelet responsiveness to clopidogrel attenuated in overweight or obese patients and why? A reverse translational study in mice.
Silencing TXNIP ameliorates high uric acid-induced insulin resistance via the IRS2/AKT and Nrf2/HO-1 pathways in macrophages.
Pharmacological inhibition of IRAK1 and IRAK4 prevents endothelial inflammation and atherosclerosis in ApoE(-/-) mice.
Ghrelin alleviates 6-hydroxydopamine-induced neurotoxicity in SH-SY5Y cells.
Ubiquitin-specific peptidase 39 promotes human glioma cells migration and invasion by facilitating ADAM9 mRNA maturation.
Isolation and characterization of secondary metabolites from the leaves of Sauropus spatulifolius Beille and their potential biological assays.
3-(3-Hydroxyphenyl)propionic acid, a microbial metabolite of quercetin, inhibits monocyte binding to endothelial cells via modulating E-selectin expression.
MACF1 promotes osteoblastic cell migration by regulating MAP1B through the GSK3beta/TCF7 pathway.
CD169-positive macrophages enhance abscopal effect of radiofrequency ablation therapy in liver cancer.
EIF1A depletion restrains human pituitary adenoma progression.
Dihydroartemisinin enhances the inhibitory effect of sorafenib on HepG2 cells by inducing ferroptosis and inhibiting energy metabolism.
Effect of Fc-Elabela-21 on renal ischemia/reperfusion injury in mice: Mediation of anti-apoptotic effect via Akt phosphorylation.
Synthesis compound XCR-7a ameliorates LPS-induced inflammatory response by inhibiting the phosphorylation of c-Fos.
CAMKK2 Defines Ferroptosis Sensitivity of Melanoma Cells by Regulating AMPK‒NRF2 Pathway.
Luteolin alleviates ischemia/reperfusion injury-induced no-reflow by regulating Wnt/β-catenin signaling in rats.
Impaired vessel relaxation response and increased infarct size in smooth muscle cannabinoid receptor 1 knockout mice.
Minimally modified low-density lipoprotein upregulates mouse mesenteric arterial 5-HT(1B) receptor in vivo via activation of the JAK2/STAT3 pathway.
Overexpression of DOCK6 in oral squamous cell cancer promotes cellular migration and invasion and is associated with poor prognosis.
Icaritin alleviates docetaxel-induced skin injury by suppressing reactive oxygen species via estrogen receptors.
cGAS guards against chromosome end-to-end fusions during mitosis and facilitates replicative senescence.
Long noncoding RNA UBA6-AS1 inhibits the malignancy of ovarian cancer cells via suppressing the decay of UBA6 mRNA.
Metformin promotes histone deacetylation of optineurin and suppresses tumour growth through autophagy inhibition in ocular melanoma.
Extracellular vesicle-mediated delivery of circDYM alleviates CUS-induced depressive-like behaviours.
Overexpression of DUOX2 mediates doxorubicin resistance and predicts prognosis of pancreatic cancer.
β-Hydroxybutyrate impairs neutrophil migration distance through activation of a protein kinase C and myosin light chain 2 signaling pathway in ketotic cows.
Bioglass promotes wound healing by inhibiting endothelial cell pyroptosis through regulation of the connexin 43/reactive oxygen species (ROS) signaling pathway.
TNFSF9 promotes metastasis of pancreatic cancer by regulating M2 polarization of macrophages through Src/FAK/p-Akt/IL-1β signaling.
Artesunate attenuates atherosclerosis by inhibiting macrophage M1-like polarization and improving metabolism.
Exosomal myeloperoxidase as a biomarker of deep venous thrombosis.
Clerodane diterpene induces apoptosis/anoikis and suppresses migration and invasion of human bladder cancer cells through the histone deacetylases, integrin-focal adhesion kinase, and matrix metalloproteinase 9 signalling pathways.
Curculigoside mitigates hepatic ischemia/reperfusion-induced oxidative stress, inflammation, and apoptosis via activation of the Nrf-2/HO-1 pathway.
Effects of butein on human osteosarcoma cell proliferation, apoptosis, and autophagy through oxidative stress.
G-protein Coupled Receptor 34 Promotes Gliomagenesis by Inducing Proliferation and Malignant Phenotype via TGF-Beta/Smad Signaling Pathway.
Vascular endothelial growth factor-A/vascular endothelial growth factor2 signaling in spinal neurons contributes to bone cancer pain.
ROS/PI3K/Akt and Wnt/β-catenin signalings activate HIF-1α-induced metabolic reprogramming to impart 5-fluorouracil resistance in colorectal cancer.
EndMT: New findings on the origin of myofibroblasts in endometrial fibrosis of intrauterine adhesions.
Endothelial cell metabolic memory causes cardiovascular dysfunction in diabetes.
AHSA1 is a promising therapeutic target for cellular proliferation and proteasome inhibitor resistance in multiple myeloma.
Annexin A1 promotes the progression of bladder cancer via regulating EGFR signaling pathway.
CRISPR/Cas9 delivery by NIR-responsive biomimetic nanoparticles for targeted HBV therapy.
MiR-30c-5p loss-induced PELI1 accumulation regulates cell proliferation and migration via activating PI3K/AKT pathway in papillary thyroid carcinoma.
Trans-cinnamaldehyde suppresses microtubule detyrosination and alleviates cardiac hypertrophy.
Cisplatin induces damage of auditory cells: Possible relation with dynamic variation in calcium homeostasis and responding channels.
Protective role of m(6)A binding protein YTHDC2 on CCNB2 in manganese-induced spermatogenesis dysfunction.
Immunomodulatory Effect of Serum Exosomes From Crohn Disease on Macrophages via Let-7b-5p/TLR4 Signaling.
Heat Shock Protein 60 Restricts Release of Mitochondrial dsRNA to Suppress Hepatic Inflammation and Ameliorate Non-Alcoholic Fatty Liver Disease in Mice.
A novel ICG-labeled cyclic TMTP1 peptide dimer for sensitive tumor imaging and enhanced photothermal therapy in vivo.
STING orchestrates the crosstalk between polyunsaturated fatty acid metabolism and inflammatory responses.
SIRT6 protects vascular smooth muscle cells from osteogenic transdifferentiation via Runx2 in chronic kidney disease.
Enteromorpha prolifera polysaccharide-zinc complex modulates the immune response and alleviates LPS-induced intestinal inflammation via inhibiting the TLR4/NF-κB signaling pathway.
Steatosis induced by nonylphenol in HepG2 cells and the intervention effect of curcumin.
ACSL4 Directs Intramuscular Adipogenesis and Fatty Acid Composition in Pigs.
mTOR inhibitor improves testosterone-induced myocardial hypertrophy in hypertensive rats.
MiR-29a Curbs Hepatocellular Carcinoma Incidence via Targeting of HIF-1α and ANGPT2.
m6A modifications regulate intestinal immunity and rotavirus infection.
Renoprotective activity of Ribes diacanthum pall (RDP) against inflammation in cisplatin-stimulated mice model and human renal tubular epithelial cells.
Protective effect of oligosaccharides isolated from Panax ginseng C. A. Meyer against UVB-induced skin barrier damage in BALB/c hairless mice and human keratinocytes.
CHMP2B regulates TDP-43 phosphorylation and cytotoxicity independent of autophagy via CK1.
Hyaluronic Acid-Modified Nanoparticles Self-Assembled from Linoleic Acid-Conjugated Chitosan for the Codelivery of miR34a and Doxorubicin in Resistant Breast Cancer.
Long non-coding RNA lncC11orf54-1 modulates neuroinflammatory responses by activating NF-κB signaling during meningitic Escherichia coli infection.
Islet amyloid polypeptide cross-seeds tau and drives the neurofibrillary pathology in Alzheimer's disease.
Hsa_circ_0076931 suppresses malignant biological properties, down-regulates miR-6760-3p through direct binding, and up-regulates CCBE1 in glioma.
Functional Characterization of FH Mutation c.557G>A Underlies Uterine Leiomyomas.
Lipid Droplets Are Beneficial for Rabies Virus Replication by Facilitating Viral Budding.
Loss of miR-31-5p drives hematopoietic stem cell malignant transformation and restoration eliminates leukemia stem cells in mice.
The Role of Sirtuin 1 in Palmitic Acid-Induced Endoplasmic Reticulum Stress in Cardiac Myoblasts.
Non-viral siRNA transfection of primary mesenchymal stromal cells (MSCs): Assessment of tyrosine-modified PEI and PPI efficacy and biocompatibility.
Upregulation of CENPM facilitates lung adenocarcinoma progression via PI3K/AKT/mTOR signaling pathway.
Diffuse large B-cell lymphoma-derived exosomes push macrophage polarization toward M2 phenotype via GP130/STAT3 signaling pathway.
SNX27 suppresses SARS-CoV-2 infection by inhibiting viral lysosome/late endosome entry.
Parkinson's disease protein PARK7 prevents metabolite and protein damage caused by a glycolytic metabolite.
Golgi phosphoprotein 3 promotes angiogenesis and sorafenib resistance in hepatocellular carcinoma via upregulating exosomal miR-494-3p.
N6-Methyladenosine Modification of CDH1 mRNA Promotes PM2.5-Induced Pulmonary Fibrosis via Mediating Epithelial Mesenchymal Transition.
WASH interacts with Ku to regulate DNA double-stranded break repair.
HERC3 regulates epithelial-mesenchymal transition by directly ubiquitination degradation EIF5A2 and inhibits metastasis of colorectal cancer.
N6-methyladenosine demethylase FTO promotes growth and metastasis of gastric cancer via m(6)A modification of caveolin-1 and metabolic regulation of mitochondrial dynamics.
Phosphodiesterase 4D promotes angiotensin II-induced hypertension in mice via smooth muscle cell contraction.
An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.
Epimedium protects against dyszoospermia in mice with Pex3 knockout by exerting antioxidant effects and regulating the expression level of P16.
DDX39B contributes to the proliferation of colorectal cancer through direct binding to CDK6/CCND1.
Lipid reprogramming induced by the TFEB-ERRα axis enhanced membrane fluidity to promote EC progression.
Discovery of a Covalent FEM1B Recruiter for Targeted Protein Degradation Applications.
Overexpression of Twist1 in vascular endothelial cells promotes pathological retinal angiogenesis in mice.
Metastasis enhancer PGRMC1 boosts store-operated Ca(2+) entry by uncoiling Ca(2+) sensor STIM1 for focal adhesion turnover and actomyosin formation.
Canonical WNT pathway inhibition reduces ATP synthesis rates in glioblastoma stem cells.
Ferroptosis-related lncRNA pairs to predict the clinical outcome and molecular characteristics of pancreatic ductal adenocarcinoma.
4D-quantitative proteomics signature of asthenozoospermia and identification of extracellular matrix protein 1 as a novel biomarker for sperm motility.
The histone methyltransferase DOT1L is a new epigenetic regulator of pulmonary fibrosis.
LncRNA SNHG16 accelerates atherosclerosis and promotes ox-LDL-induced VSMC growth via the miRNA-22-3p/HMGB2 axis.
Salidroside alleviates oxidative stress and apoptosis via AMPK/Nrf2 pathway in DHT-induced human granulosa cell line KGN.
C9orf72 knockdown alleviates hepatic insulin resistance by promoting lipophagy.
Iron overload inhibits cell proliferation and promotes autophagy via PARP1/SIRT1 signaling in endometriosis and adenomyosis.
Kinesin family member 23 exerts a protumor function in breast cancer via stimulation of the Wnt/β-catenin pathway.
BDE-47 induced PC-12 cell differentiation via TrkA downstream pathways and caused the loss of hippocampal neurons in BALB/c mice.
Genome-wide CRISPR/Cas9 library screen identifies PCMT1 as a critical driver of ovarian cancer metastasis.
Weakened interaction of ATG14 and the SNARE complex blocks autophagosome-lysosome fusion contributes to fluoride-induced developmental neurotoxicity.
In vivo assessment of molybdenum and cadmium co-induce nephrotoxicity via causing calcium homeostasis disorder and autophagy in ducks (Anas platyrhyncha).
Congenital cataract-causing mutation βB1-L116P is prone to amyloid fibrils aggregation and protease degradation with low structural stability.
Protective effects of polysaccharides from Atractylodes macrocephalae Koidz. against dextran sulfate sodium induced intestinal mucosal injury on mice.
Inhibition of Rac1 attenuates radiation-induced lung injury while suppresses lung tumor in mice.
Discovery of Orally Available Retinoic Acid Receptor-Related Orphan Receptor γ-t/Dihydroorotate Dehydrogenase Dual Inhibitors for the Treatment of Refractory Inflammatory Bowel Disease.
Small Heat Shock Protein 22 Improves Cognition and Learning in the Tauopathic Brain.
Sea Cucumber Peptides Attenuated the Scopolamine-Induced Memory Impairment in Mice and Rats and the Underlying Mechanism.
Control of Expression of Key Cell Cycle Enzymes Drives Cell Line-Specific Functions of CDK7 in Human PDAC Cells.
Deficiency of two-pore segment channel 2 contributes to systemic lupus erythematosus via regulation of apoptosis and cell cycle.
New IMB16-4 Nanoparticles Improved Oral Bioavailability and Enhanced Anti-Hepatic Fibrosis on Rats.
Linc01133 contributes to gastric cancer growth by enhancing YES1-dependent YAP1 nuclear translocation via sponging miR-145-5p.
Gut microbiota promotes cholesterol gallstone formation by modulating bile acid composition and biliary cholesterol secretion.
Aging is associated with increased brain iron through cortex-derived hepcidin expression.
Cofilin 1 promotes the pathogenicity and transmission of pathological α-synuclein in mouse models of Parkinson's disease.
Anti-tumor effect of Yanggan Huayu granule by inducing AKT-mediated apoptosis in hepatocellular carcinoma.
Xiaoyao powder improves endometrial receptivity via VEGFR-2-mediated angiogenesis through the activation of the JNK and P38 signaling pathways.
Mechanical force promotes dimethylarginine dimethylaminohydrolase 1-mediated hydrolysis of the metabolite asymmetric dimethylarginine to enhance bone formation.
RSL1D1 promotes the progression of colorectal cancer through RAN-mediated autophagy suppression.
Effects of Restricted Feeding on Growth Performance, Intestinal Immunity, and Skeletal Muscle Development in New Zealand Rabbits.
RNA N(6)-methyladenosine modulates endothelial atherogenic responses to disturbed flow in mice.
Ajuba functions as a co-activator of C/EBPβ to induce expression of PPARγ and C/EBPα during adipogenesis.
Highly sensitive detection of multiple proteins from single cells by MoS(2)-FET biosensors.
Delayed inhibition of ERK and p38 attenuates neuropathic pain without affecting motor function recovery after peripheral nerve injury.
NMN recruits GSH to enhance GPX4-mediated ferroptosis defense in UV irradiation induced skin injury.
Docosahexaenoic acid reduces hypoglycemia-induced neuronal necroptosis via the peroxisome proliferator-activated receptor γ/nuclear factor-κB pathway.
Epithelial Wntless regulates postnatal alveologenesis.
The Impact of Long-term Physical Inactivity on Adipose Tissue Immunometabolism.
Wuzhuyu Decoction relieves hyperalgesia by regulating central and peripheral 5-HT in chronic migraine model rats.
Normalizing hyperactivity of the Gunn rat with bilirubin-induced neurological disorders via ketanserin.
Dapagliflozin alleviates advanced glycation end product induced podocyte injury through AMPK/mTOR mediated autophagy pathway.
FOXL2 regulates the expression of the Col4a1 collagen gene in chicken granulosa cells.
Transgelin-2 interacts with CD44 to regulate Notch1 signaling pathway and participates in colorectal cancer proliferation and migration.
DsbA-L interacts with VDAC1 in mitochondrion-mediated tubular cell apoptosis and contributes to the progression of acute kidney disease.
DHHC5 facilitates oligodendrocyte development by palmitoylating and activating STAT3.
AKT1/HK2 Axis-mediated Glucose Metabolism: A Novel Therapeutic Target of Sulforaphane in Bladder Cancer.
Divergent immunometabolic changes in adipose tissue and skeletal muscle with ageing in healthy humans.
Pan-cancer multi-omics analyses reveal crosstalk between the Hippo and immune signaling pathways in the tumor microenvironment.
MiR-597-5p suppresses the progression of hepatocellular carcinoma via targeting transcriptional enhancer associate domain transcription factor 1 (TEAD1).
Follicle-stimulating hormone regulates glycolysis of water buffalo follicular granulosa cells through AMPK/SIRT1 signalling pathway.
Inhibition of gap junction communication between cells can induce apoptosis of corpus cavernosum smooth muscle in guinea pigs.
Crosstalk Between RPE Cells and Choroidal Endothelial Cells via the ANXA1/FPR2/SHP2/NLRP3 Inflammasome/Pyroptosis Axis Promotes Choroidal Neovascularization.
Supervillin Contributes to LPS-induced Inflammatory Response in THP-1 Cell-derived Macrophages.
PDCD4 Simultaneously Promotes Microglia Activation via PDCD4-MAPK-NF-κB Positive Loop and Facilitates Neuron Apoptosis During Neuroinflammation.
Tenascin-C Participates Pulmonary Injury Induced by Paraquat Through Regulating TLR4 and TGF-β Signaling Pathways.
CACNA1B facilitates breast cancer cell growth and migration by regulating cyclin D1 and EMT: the implication of CACNA1B in breast cancer.
The m(6)A reading protein YTHDF3 potentiates tumorigenicity of cancer stem-like cells in ocular melanoma through facilitating CTNNB1 translation.
Tanshinone IIA inhibits gastric cancer cell stemness through inducing ferroptosis.
Estrogen receptor beta increases clear cell renal cell carcinoma stem cell phenotype via altering the circPHACTR4/miR-34b-5p/c-Myc signaling.
Spindle pole body component 24 homolog potentiates tumor progression via regulation of SRY-box transcription factor 2 in clear cell renal cell carcinoma.
The STING-IRF3 pathway contributes to paraquat-induced acute lung injury.
Neuroglobin expression and function in the temporal cortex of bilirubin encephalopathy rats.
Phosphorylated PAMAM dendrimers: an analog of dentin non-collagenous proteins, enhancing the osteo/odontogenic differentiation of dental pulp stem cells.
Altered transsulfuration pathway enzymes and redox homeostasis in inherited retinal degenerative diseases.
Retinal degeneration in humanized mice expressing mutant rhodopsin under the control of the endogenous murine promoter.
NCAPH promotes cell proliferation and inhibits cell apoptosis of bladder cancer cells through MEK/ERK signaling pathway.
Demethylenetetrahydroberberine protects dopaminergic neurons in a mouse model of Parkinson's disease.
Assessing Mitochondrial DNA Release into the Cytosol and Subsequent Activation of Innate Immune-related Pathways in Mammalian Cells.
Combination of the 6-thioguanine and disulfiram/Cu synergistically inhibits proliferation of triple-negative breast cancer cells by enhancing DNA damage and disrupting DNA damage checkpoint.
Dietary mulberry-leaf flavonoids improve the eggshell quality of aged breeder hens.
Pre-clinical study of human umbilical cord mesenchymal stem cell transplantation for the treatment of traumatic brain injury: safety evaluation from immunogenic and oncogenic perspectives.
Upregulated hexokinase 2 expression induces the apoptosis of dopaminergic neurons by promoting lactate production in Parkinson's disease.
Withaferin A alleviates ethanol-induced liver injury by inhibiting hepatic lipogenesis.
FGF19 protects against obesity-induced bone loss by promoting osteogenic differentiation.
Ubiquitin-specific peptidase 2 inhibits epithelial-mesenchymal transition in clear cell renal cell carcinoma metastasis by downregulating the NF-κB pathway.
Long non-coding RNA TRPM2 antisense RNA as a potential therapeutic target promotes tumorigenesis and metastasis in esophageal cancer.
Timosaponin B-II alleviates osteoarthritis-related inflammation and extracellular matrix degradation through inhibition of mitogen-activated protein kinases and nuclear factor-κB pathways in vitro.
Calcium-activated nucleotides 1 (CANT1)-driven nuclear factor-k-gene binding (NF-ĸB) signaling pathway facilitates the lung cancer progression.
3-hydroxy butyrate dehydrogenase 2 deficiency aggravates systemic lupus erythematosus progression in a mouse model by promoting CD40 ligand demethylation.
Knockdown of ADORA2A antisense RNA 1 inhibits cell proliferation and enhances imatinib sensitivity in chronic myeloid leukemia.
circRNAome profiling reveals circFgfr2 regulates myogenesis and muscle regeneration via a feedback loop.
Histone deacetylase inhibitors inhibit cervical cancer growth through Parkin acetylation-mediated mitophagy.
Anti-aging effects of chlorpropamide depend on mitochondrial complex-II and the production of mitochondrial reactive oxygen species.
Celastrol attenuates the remodeling of pulmonary vascular and right ventricular in monocrotaline-induced pulmonary arterial hypertension in rats.
Maternal exposure to PM2.5 induces the testicular cell apoptosis in offspring triggered by the UPR-mediated JNK pathway.
Downregulation of acylglycerol kinase suppresses high-glucose-induced endothelial-mesenchymal transition in human retinal microvascular endothelial cells through regulating the LPAR1/TGF-β/Notch signaling pathway.
Identification of key biomarkers and immune infiltration in renal interstitial fibrosis.
Cold-inducible RNA-binding protein regulates cyclin B1 against spermatogenesis arrest caused by heat stress.
Phenotypic and genotypic changes in obesity and type 2 diabetes of male KK mice with aging.
Mechanisms and Molecular Targets of BuShenHuoXue Formula for Osteoarthritis.
Rpsa Signaling Regulates Cortical Neuronal Morphogenesis via Its Ligand, PEDF, and Plasma Membrane Interaction Partner, Itga6.
Neuroprotective effects of alisol A 24-acetate on cerebral ischaemia-reperfusion injury are mediated by regulating the PI3K/AKT pathway.
Pigment epithelium-derived factor may induce antidepressant phenotypes in mice by the prefrontal cortex.
Hepatocyte nuclear factor 4 gamma (HNF4G) is correlated with poor prognosis and promotes tumor cell growth by inhibiting caspase-dependent intrinsic apoptosis in colorectal cancer.
Aloe-emodin derivative produces anti-atherosclerosis effect by reinforcing AMBRA1-mediated endothelial autophagy.
Design and synthesis of marine sesterterpene analogues as novel estrogen receptor α degraders for breast cancer treatment.
Toddalolactone protects against osteoarthritis by ameliorating chondrocyte inflammation and suppressing osteoclastogenesis.
Intracellular CYTL1, a novel tumor suppressor, stabilizes NDUFV1 to inhibit metabolic reprogramming in breast cancer.
Proteomic Identification of the SLC25A46 Interactome in Transgenic Mice Expressing SLC25A46-FLAG.
Differential regulation of progranulin derived granulin peptides.
Amino acid starvation-induced LDLR trafficking accelerates lipoprotein endocytosis and LDL clearance.
Licochalcone B specifically inhibits the NLRP3 inflammasome by disrupting NEK7-NLRP3 interaction.
Commonality and diversity in tRNA substrate recognition in t6A biogenesis by eukaryotic KEOPSs.
NVP-AUY922 alleviates radiation-induced lung injury via inhibition of autophagy-dependent ferroptosis.
Characterization of lncRNA functioning in ovine conceptuses and endometria during the peri-implantation period.
CircCYP24A1 hampered malignant phenotype of renal cancer carcinoma through modulating CMTM-4 expression via sponging miR-421.
Widespread Mislocalization of FUS Is Associated With Mitochondrial Abnormalities in Skeletal Muscle in Amyotrophic Lateral Sclerosis With FUS Mutations.
Comprehensive Analysis of Protein Acetylation and Glucose Metabolism in Mouse Brains Infected with Rabies Virus.
Targeting polarized phenotype of microglia via IL6/JAK2/STAT3 signaling to reduce NSCLC brain metastasis.
PD-L1 mediates lung fibroblast to myofibroblast transition through Smad3 and β-catenin signaling pathways.
Avian Hepatitis E Virus ORF2 Protein Interacts with Rap1b to Induce Cytoskeleton Rearrangement That Facilitates Virus Internalization.
Listeria toxin promotes phosphorylation of the inflammasome adaptor ASC through Lyn and Syk to exacerbate pathogen expansion.
D-mannose facilitates immunotherapy and radiotherapy of triple-negative breast cancer via degradation of PD-L1.
S-20, a steroidal saponin from the berries of black nightshade, exerts anti-multidrug resistance activity in K562/ADR cells through autophagic cell death and ERK activation.
Cadmium and molybdenum co-induce pyroptosis and apoptosis via the PTEN/PI3K/AKT axis in the livers of Shaoxing ducks (Anas platyrhynchos).
CircNEIL3 mediates pyroptosis to influence lung adenocarcinoma radiotherapy by upregulating PIF1 through miR-1184 inhibition.
WT1 suppresses follicle-stimulating hormone-induced progesterone secretion by regulating ERK1/2 pathway in chicken preovulatory granulosa cells.
OTUB2 regulates KRT80 stability via deubiquitination and promotes tumour proliferation in gastric cancer.
Autophagic Schwann cells promote perineural invasion mediated by the NGF/ATG7 paracrine pathway in pancreatic cancer.
Maresin 1 promotes nerve regeneration and alleviates neuropathic pain after nerve injury.
LncRNA FIRRE functions as a tumor promoter by interaction with PTBP1 to stabilize BECN1 mRNA and facilitate autophagy.
Mesenchyme homeobox 2 has a cancer-inhibiting function in breast carcinoma via affection of the PI3K/AKT/mTOR and ERK1/2 pathways.
The deubiquitinating enzyme USP20 regulates the stability of the MCL1 protein.
CRISPR screening of E3 ubiquitin ligases reveals Ring Finger Protein 185 as a novel tumor suppressor in glioblastoma repressed by promoter hypermethylation and miR-587.
METTL3 promotes oxaliplatin resistance of gastric cancer CD133+ stem cells by promoting PARP1 mRNA stability.
Elevated expression of the rhythm gene NFIL3 promotes the progression of TNBC by activating NF-κB signaling through suppression of NFKBIA transcription.
Nrf2 activation reprograms macrophage intermediary metabolism and suppresses the type I interferon response.
PINK1-parkin-mediated neuronal mitophagy deficiency in prion disease.
E3 ligase RNF167 and deubiquitinase STAMBPL1 modulate mTOR and cancer progression.
Chronic exposure to polystyrene microplastics induced male reproductive toxicity and decreased testosterone levels via the LH-mediated LHR/cAMP/PKA/StAR pathway.
Circ-AFAP1 promote clear cell renal cell carcinoma growth and angiogenesis by the Circ-AFAP1/miR-374b-3p/VEGFA signaling axis.
Preparation, Characterization, Evaluation of Neuroprotective Effect, and Related Mechanisms of Phosphatidylserine Emulsion in 5- and 12-Week Old Mice.
Protein C receptor maintains cancer stem cell properties via activating lipid synthesis in nasopharyngeal carcinoma.
Disuse-associated loss of the protease LONP1 in muscle impairs mitochondrial function and causes reduced skeletal muscle mass and strength.
γ-mangostin attenuates amyloid-β42-induced neuroinflammation and oxidative stress in microglia-like BV2 cells via the mitogen-activated protein kinases signaling pathway.
Synthesis of lathyrane diterpenoid nitrogen-containing heterocyclic derivatives and evaluation of their anti-inflammatory activities.
Synthesis and biological evaluation of aminobenzamides containing purine moiety as class I histone deacetylases inhibitors.
Liquiritigenin alleviates doxorubicin-induced chronic heart failure via promoting ARHGAP18 and suppressing RhoA/ROCK1 pathway.
Substrate rigidity dictates colorectal tumorigenic cell stemness and metastasis via CRAD-dependent mechanotransduction.
TBK1-METTL3 axis facilitates antiviral immunity.
Defective STAT5 Activation and Aberrant Expression of BCL6 in Naive CD4 T Cells Enhances Follicular Th Cell-like Differentiation in Patients with Granulomatosis with Polyangiitis.
Cotranslational interaction of human EBP50 and ezrin overcomes masked binding site during complex assembly.
Cartilage Repair Using Clematis Triterpenoid Saponin Delivery Microcarrier, Cultured in a Microgravity Bioreactor Prior to Application in Rabbit Model.
Multienzymatic Antioxidant Activity of Manganese-Based Nanoparticles for Protection against Oxidative Cell Damage.
METTL3 overexpression aggravates LPS-induced cellular inflammation in mouse intestinal epithelial cells and DSS-induced IBD in mice.
Downregulation of macrophage migration inhibitory factor attenuates NLRP3 inflammasome mediated pyroptosis in sepsis-induced AKI.
MiR-652-5p elevated glycolysis level by targeting TIGAR in T-cell acute lymphoblastic leukemia.
ZHX2 inhibits thyroid cancer metastasis through transcriptional inhibition of S100A14.
Comprehensive analysis of N(6)-methyladenosine regulators with the tumor immune landscape and correlation between the insulin-like growth factor 2 mRNA-binding protein 3 and programmed death ligand 1 in bladder cancer.
PEBP balances apoptosis and autophagy in whitefly upon arbovirus infection.
Development of a skin- and neuro-attenuated live vaccine for varicella.
Overexpression of bmp4, dazl, nanos3 and sycp2 in Hu Sheep Leydig Cells Using CRISPR/dcas9 System Promoted Male Germ Cell Related Gene Expression.
LncRNA MT1DP promotes cadmium-induced DNA replication stress by inhibiting chromatin recruitment of SMARCAL1.
OGDHL ameliorates cognitive impairment and Alzheimer's disease-like pathology via activating Wnt/β-catenin signaling in Alzheimer's disease mice.
Anti-fatigue effect of hypericin in a chronic forced exercise mouse model.
FERMT1 contributes to the migration and invasion of nasopharyngeal carcinoma through epithelial-mesenchymal transition and cell cycle arrest.
Immune-responsive gene 1/itaconate activates nuclear factor erythroid 2-related factor 2 in microglia to protect against spinal cord injury in mice.
LncRNA Tug1 maintains blood-testis barrier integrity by modulating Ccl2 expression in high-fat diet mice.
Grass Carp Reovirus Nonstructural Proteins Avoid Host Antiviral Immune Response by Targeting the RLR Signaling Pathway.
An alternatively spliced STING isoform localizes in the cytoplasmic membrane and directly senses extracellular cGAMP.
A biomimetic nanodrug self-assembled from small molecules for enhanced ferroptosis therapy.
Maternal sevoflurane exposure affects neural stem cell differentiation in offspring rats through NRF2 signaling.
Blockade of Nuclear β-Catenin Signaling via Direct Targeting of RanBP3 with NU2058 Induces Cell Senescence to Suppress Colorectal Tumorigenesis.
Lactobacillus reuteri normalizes altered fear memory in male Cntnap4 knockout mice.
Leukemia inhibitory factor is a therapeutic target for renal interstitial fibrosis.
A signalling pathway for transcriptional regulation of sleep amount in mice.
PPP1R14D promotes the proliferation, migration and invasion of lung adenocarcinoma via the PKCα/BRAF/MEK/ERK signaling pathway.
Red ginseng polysaccharide exhibits anticancer activity through GPX4 downregulation-induced ferroptosis.
Baicalin protects against renal interstitial fibrosis in mice by inhibiting the TGF-β/Smad signalling pathway.
SRT1720 as an SIRT1 activator for alleviating paraquat-induced models of Parkinson's disease.
Mitochondrial DNA mediates immunoparalysis of dendritic cells in sepsis via STING signalling.
Knockdown of ZBTB11 impedes R-loop elimination and increases the sensitivity to cisplatin by inhibiting DDX1 transcription in bladder cancer.
ALA-PDT regulates macrophage M1 polarization via ERK/MAPK-NLRP3 pathway to promote the early inflammatory response.
Characterization and functional analysis of lncRNA2690 in regulating the growth cycle of the hair follicle in rabbits.
Bone marrow-derived mesenchymal stem cells ameliorate severe acute pancreatitis by inhibiting oxidative stress in rats.
FAT1 downregulation enhances stemness and cisplatin resistance in esophageal squamous cell carcinoma.
Bone marrow mesenchymal stem cells-derived exosomes mediate nuclear receptor coactivator-3 expression in osteoblasts by delivering miR-532-5p to influence osteonecrosis of the femoral head development.
Expression analysis of irisin during different development stages of skeletal muscle in mice.
Modulation of Microglia M2 Polarization and Alleviation of Hippocampal Neuron Injury By MiR-106b-5p/RGMa in a Mouse Model of Status Epilepticus.
Inhibition of Circ-Snrk ameliorates apoptosis and inflammation in acute kidney injury by regulating the MAPK pathway.
ATG5-Mediated Autophagy May Inhibit Pyroptosis to Ameliorate Oleic Acid-Induced Hepatocyte Steatosis.
Brentuxinmab vedotin, alone or combine with bendamustine in the treatment of natural killer T cell lymphoma.
Di(2-ethylhexyl) phthalate induced thyroid toxicity via endoplasmic reticulum stress: In vivo and in vitro study.
Design, synthesis, and cytotoxic activities of isaindigotone derivatives as potential anti-gastric cancer agents.
Deciphering the map of METTL14-mediated lncRNA m6A modification at the transcriptome-wide level in breast cancer.
Mitochondrial dynamics, Leydig cell function, and age-related testosterone deficiency.
WTAP dysregulation-mediated HMGN3-m6A modification inhibited trophoblast invasion in early-onset preeclampsia.
BDE-47 disturbs the immune response of lymphocytes to LPS by downregulating NF-κB pathway.
The interaction between E3 ubiquitin ligase Parkin and mitophagy receptor PHB2 links inner mitochondrial membrane ubiquitination to efficient mitophagy.
OCA7 is a melanosome membrane protein that defines pigmentation by regulating early stages of melanosome biogenesis.
Cartwheel disassembly regulated by CDK1-cyclin B kinase allows human centriole disengagement and licensing.
Lonidamine and domperidone inhibit expansion of transformed cell areas by modulating motility of surrounding nontransformed cells.
Glucose-6-phosphate dehydrogenase exerts antistress effects independently of its enzymatic activity.
Development of nanocubosomes co-loaded with dual anticancer agents curcumin and temozolomide for effective Colon cancer therapy.
A recombinant scFv antibody-based fusion protein that targets EGFR associated with IMPDH2 downregulation and its drug conjugate show therapeutic efficacy against esophageal cancer.
LRPPRC inhibits autophagy and promotes foam cell formation in atherosclerosis.
Ferroptosis contributes to hypoxic-ischemic brain injury in neonatal rats: Role of the SIRT1/Nrf2/GPx4 signaling pathway.
CircHOMER1 aggravates oxidative stress, inflammation and extracellular matrix deposition in high glucose-induced human mesangial cells.
SPRY1 promotes cell proliferation and inhibits apoptosis by activating Hedgehog pathway in acute myeloid leukemia.
CUL4B increases platinum-based drug resistance in colorectal cancer through EMT: A study in its mechanism.
Autoantibody panel on small extracellular vesicles for the early detection of lung cancer.
Endothelial cell-derived S1P promotes migration and stemness by binding with GPR63 in colorectal cancer.
Monocytes deposit migrasomes to promote embryonic angiogenesis.
Atg9A-mediated mitophagy is required for decidual differentiation of endometrial stromal cells.
Melatonin enhances spermatogonia activity through promoting KIAA1429-mediated m(6)A deposition to activate the PI3K/AKT signaling.
Advanced glycation end products induce senescence of atrial myocytes and increase susceptibility of atrial fibrillation in diabetic mice.
Daidzein Activates Akt Pathway to Promote the Proliferation of Female Germline Stem Cells through Upregulating Clec11a.
WIPI2 positively regulates mitophagy by promoting mitochondrial recruitment of VCP.
KAT7-mediated CANX (calnexin) crotonylation regulates leucine-stimulated MTORC1 activity.
Defective autophagy triggered by arterial cyclic stretch promotes neointimal hyperplasia in vein grafts via the p62/nrf2/slc7a11 signaling pathway.
Differential regulatory roles of microRNAs during intramuscular adipogenesis in Chinese Guizhou Congjiang Xiang pigs.
Selective targeting of visceral adiposity by polycation nanomedicine.
Coptisine protects against hyperuricemic nephropathy through alleviating inflammation, oxidative stress and mitochondrial apoptosis via PI3K/Akt signaling pathway.
Mesenchymal stem cell-derived extracellular vesicles attenuate tPA-induced blood-brain barrier disruption in murine ischemic stroke models.
A functionalized collagen-I scaffold delivers microRNA 21-loaded exosomes for spinal cord injury repair.
Characterization of Cornulin as a Molecular Biomarker for the Progression of Oral Squamous Cell Carcinoma.
The miRNA125a-5p and miRNA125b-1-5p cluster induces cell invasion by down-regulating DDB2-reduced epithelial-to-mesenchymal transition (EMT) in colorectal cancer.
PRRX1 promotes colorectal cancer stemness and chemoresistance via the JAK2/STAT3 axis by targeting IL-6.
Maternal rodent exposure to di-(2-ethylhexyl) phthalate decreases muscle mass in the offspring by increasing myostatin.
AP-1 signaling pathway promotes pro-IL-1β transcription to facilitate NLRP3 inflammasome activation upon influenza A virus infection.
Inhibition of cell proliferation by Tas of foamy viruses through cell cycle arrest or apoptosis underlines the different mechanisms of virus-host interactions.
Regulation of host factor γ-H2AX level and location by enterovirus A71 for viral replication.
Natural carbazole alkaloid murrayafoline A displays potent anti-neuroinflammatory effect by directly targeting transcription factor Sp1 in LPS-induced microglial cells.
Corynoxine suppresses pancreatic cancer growth primarily via ROS-p38 mediated cytostatic effects.
The function of FUS in neurodevelopment revealed by the brain and spinal cord organoids.
Sphingosine kinase 1 promotes growth of glioblastoma by increasing inflammation mediated by the NF-κB /IL-6/STAT3 and JNK/PTX3 pathways.
Myoblast-derived exosomes promote the repair and regeneration of injured skeletal muscle in mice.
Epoxymicheliolide prevents dextran sulfate sodium-induced colitis in mice by inhibiting TAK1-NF-κB pathway and activating Keap1-NRF2 signaling in macrophages.
Eplerenone inhibits the macrophage-to-myofibroblast transition in rats with UUO-induced type 4 cardiorenal syndrome through the MR/CTGF pathway.
β-carotene alleviates LPS-induced inflammation through regulating STIM1/ORAI1 expression in bovine mammary epithelial cells.
Mefunidone ameliorates lipopolysaccharide-induced acute lung injury through inhibiting MAPK signaling pathway and enhancing Nrf2 pathway.
Isolongifolene alleviates liver ischemia/reperfusion injury by regulating AMPK-PGC1α signaling pathway-mediated inflammation, apoptosis, and oxidative stress.
Myostatin increases the expression of matrix metalloproteinase genes to promote preadipocytes differentiation in pigs.
The combination of nuclear receptor NR1D1 and ULK1 promotes mitophagy in adipocytes to ameliorate obesity.
Gut dysbacteriosis attenuates resistance to Mycobacterium bovis infection by decreasing cyclooxygenase 2 to inhibit endoplasmic reticulum stress.
Posttranscriptional inhibition of γ-adducin promotes the proliferation and migration of osteosarcoma cells.
Phellopterin cream exerts an anti-inflammatory effect that facilitates diabetes-associated cutaneous wound healing via SIRT1.
Near-infrared light-triggered polypyrrole promotes C2C12 cell differentiation and inhibits TNF-α induced myotube atrophy.
Yishen Xiezhuo formula ameliorates the development of cisplatin-induced acute kidney injury by attenuating renal tubular epithelial cell senescence.
RNA granule-clustered mitochondrial aminoacyl-tRNA synthetases form multiple complexes with the potential to fine-tune tRNA aminoacylation.
Elsholtzia bodinieri Vaniot Ameliorated Acute Lung Injury by NQO1, BCL2 and PTGS2 In Silico and In Vitro Analyses.
GATOR2-dependent mTORC1 activity is a therapeutic vulnerability in FOXO1 fusion-positive rhabdomyosarcoma.
The A-to-I editing of KPC1 promotes intrahepatic cholangiocarcinoma by attenuating proteasomal processing of NF-κB1 p105 to p50.
METTL3 promotes glycolysis and cholangiocarcinoma progression by mediating the m6A modification of AKR1B10.
The chromatin remodeler CHD6 promotes colorectal cancer development by regulating TMEM65-mediated mitochondrial dynamics via EGF and Wnt signaling.
USP32-regulated LAMTOR1 ubiquitination impacts mTORC1 activation and autophagy induction.
A novel small compound TOIDC suppresses lipogenesis via SREBP1-dependent signaling to curb MAFLD.
Death Receptor DR5 as a Proviral Factor for Viral Entry and Replication of Coronavirus PEDV.
Extracellular traps from activated vascular smooth muscle cells drive the progression of atherosclerosis.
Role of cardiac mitofusins in cardiac conduction following simulated ischemia-reperfusion.
ITGA5 inhibition in pancreatic stellate cells re-educates the in vitro tumor-stromal crosstalk.
A Regulatory Loop Involving miR-200c and NF-κB Modulates Mortalin Expression and Increases Cisplatin Sensitivity in an Ovarian Cancer Cell Line Model.
Toosendanin Induces Hepatocyte Damage by Inhibiting Autophagic Flux via TFEB-Mediated Lysosomal Dysfunction.
Nucleophagic Degradation of Progerin Ameliorates Defenestration in Liver Sinusoidal Endothelium Due to SIRT1-Mediated Deacetylation of Nuclear LC3.
Exosomal IL-8 derived from Lung Cancer and Colon Cancer cells induced adipocyte atrophy via NF-κB signaling pathway.
A Novel Mast Cell Stabilizer JM25-1 Rehabilitates Impaired Gut Barrier by Targeting the Corticotropin-Releasing Hormone Receptors.
RNaseH2A downregulation drives inflammatory gene expression via genomic DNA fragmentation in senescent and cancer cells.
Effect of hypoxia on HIF-1α/MDR1/VEGF expression in gastric cancer cells treated with 5-fluorouracil.
Monkfish (Lophius litulon) Peptides Ameliorate High-Fat-Diet-Induced Nephrotoxicity by Reducing Oxidative Stress and Inflammation via Regulation of Intestinal Flora.
Histone methyltransferase Smyd2 drives vascular aging by its enhancer-dependent activity.
4EBP1 senses extracellular glucose deprivation and initiates cell death signaling in lung cancer.
U1 snRNP proteins promote proximal alternative polyadenylation sites by directly interacting with 3' end processing core factors.
Pharmacological inhibition of Lin28 promotes ketogenesis and restores lipid homeostasis in models of non-alcoholic fatty liver disease.
Elabela: Negative Regulation of Ferroptosis in Trophoblasts via the Ferritinophagy Pathway Implicated in the Pathogenesis of Preeclampsia.
Involvement of pyroptosis pathway in epicardial adipose tissue - myocardium axis in experimental heart failure with preserved ejection fraction.
tRNA derived fragment tsRNA-14783 promotes M2 polarization of macrophages in keloid.
Efficient TurboID-based proximity labelling method for identifying terminal sialic acid glycosylation in living cells.
IL-22 inhibits bleomycin-induced pulmonary fibrosis in association with inhibition of IL-17A in mice.
C/D box small nucleolar RNA SNORD104 promotes endometrial cancer by regulating the 2'-O-methylation of PARP1.
SLC1A5 enhances malignant phenotypes through modulating ferroptosis status and immune microenvironment in glioma.
Diaporisoindole B Reduces Lipid Accumulation in THP-1 Macrophage Cells via MAPKs and PPARγ-LXRα Pathways and Promotes the Reverse Cholesterol Transport by Upregulating SR-B1 and LDLR in HepG2 Cells.
Biofabrication of synthetic human liver tissue with advanced programmable functions.
Oryzanol Ameliorates DSS-Stimulated Gut Barrier Damage via Targeting the Gut Microbiota Accompanied by the TLR4/NF-κB/NLRP3 Cascade Response In Vivo.
The Zinc Finger Transcription Factor Fts2 Represses the Yeast-to-Filament Transition in the Dimorphic Yeast Yarrowia lipolytica.
Huntington disease oligodendrocyte maturation deficits revealed by single-nucleus RNAseq are rescued by thiamine-biotin supplementation.
Discovery and mechanism studies of a novel ATG4B inhibitor Ebselen by drug repurposing and its anti-colorectal cancer effects in mice.
Myo-Inositol Supplementation Alleviates Cisplatin-Induced Acute Kidney Injury via Inhibition of Ferroptosis.
Chemotherapeutic Drugs Induce Different Gut Microbiota Disorder Pattern and NOD/RIP2/NF-κB Signaling Pathway Activation That Lead to Different Degrees of Intestinal Injury.
Ubiquitination of SARS-CoV-2 ORF7a Prevents Cell Death Induced by Recruiting BclXL To Activate ER Stress.
NLRP3 deficiency decreases alcohol intake controlling anxiety-like behavior via modification of glutamatergic transmission in corticostriatal circuits.
Irisin promotes the browning of white adipocytes tissue by AMPKα1 signaling pathway.
Circadian gene CSNK1D promoted the progression of hepatocellular carcinoma by activating Wnt/β-catenin pathway via stabilizing Dishevelled Segment Polarity Protein 3.
Regulation of Cyclin D1 Degradation by Ubiquitin-Specific Protease 27X Is Critical for Cancer Cell Proliferation and Tumor Growth.
Polysaccharide of Atractylodes macrocephala Koidz Alleviates Cyclophosphamide-Induced Thymus Ferroptosis in Gosling.
Evidence linking APOBEC3B genesis and evolution of innate immune antagonism by gamma-herpesvirus ribonucleotide reductases.
Plasma exosomal miR-199a-3p downregulates cell proliferation and migration in Hirschsprung's disease by targeting mTOR.
Decreased Expression of EZH2 in Granulosa Cells Contributes to Endometriosis-Associated Infertility by Targeting IL-1R2.
Allosteric Inhibition of c-Abl to Induce Unfolded Protein Response and Cell Death in Multiple Myeloma.
Angiogenesis-Browning Interplay Mediated by Asprosin-Knockout Contributes to Weight Loss in Mice with Obesity.
Anti-polycystic ovary syndrome effect of electroacupuncture: IMD inhibits ER stress-mediated apoptosis and autophagy in granulosa cells.
Targeting TLR2/Rac1/cdc42/JNK Pathway to Reveal That Ruxolitinib Promotes Thrombocytopoiesis.
Ivermectin Attenuates CCl(4)-Induced Liver Fibrosis in Mice by Suppressing Hepatic Stellate Cell Activation.
BAF53A drives colorectal cancer development by regulating DUSP5-mediated ERK phosphorylation.
The selective NLRP3 inflammasome inhibitor MCC950 improves isoproterenol-induced cardiac dysfunction by inhibiting cardiomyocyte senescence.
EBV promotes vascular mimicry of dormant cancer cells by potentiating stemness and EMT.
Prohibitin 1 regulates mtDNA release and downstream inflammatory responses.
BNIP3L/NIX regulates both mitophagy and pexophagy.
IGF2BP2-induced circRUNX1 facilitates the growth and metastasis of esophageal squamous cell carcinoma through miR-449b-5p/FOXP3 axis.
The traditional chinese medicine monomer Ailanthone improves the therapeutic efficacy of anti-PD-L1 in melanoma cells by targeting c-Jun.
Regulation of Parkin in Cr (VI)-induced mitophagy in chicken hepatocytes.
Melatonin protects oocytes from cadmium exposure-induced meiosis defects by changing epigenetic modification and enhancing mitochondrial morphology in the mouse.
Discovery and optimization of 4-anilinoquinazoline derivatives spanning ATP binding site and allosteric site as effective EGFR-C797S inhibitors.
Coxsackievirus Group B3 Has Oncolytic Activity against Colon Cancer through Gasdermin E-Mediated Pyroptosis.
The P681H Mutation in the Spike Glycoprotein of the Alpha Variant of SARS-CoV-2 Escapes IFITM Restriction and Is Necessary for Type I Interferon Resistance.
Autophagy inhibition and reactive oxygen species elimination by acetyl-CoA acetyltransferase 1 through fused in sarcoma protein to promote prostate cancer.
NLRP6 Induces Lung Injury and Inflammation Early in Brucella and Influenza Coinfection.
ML216-Induced BLM Helicase Inhibition Sensitizes PCa Cells to the DNA-Crosslinking Agent Cisplatin.
Silibinin Overcomes EMT-Driven Lung Cancer Resistance to New-Generation ALK Inhibitors.
Long noncoding RNA GAS5 alleviates the inflammatory response of human periodontal ligament stem cells by regulating the NF-κB signalling pathway.
DMSO-soluble smoking particles up-regulate the vascular endothelin receptors through AMPK-SIRT1 and MAPK pathways.
LS-007 inhibits melanoma growth via inducing apoptosis and cell cycle arrest and regulating macrophage polarization.
Novel shikonin derivatives suppress cell proliferation, migration and induce apoptosis in human triple-negative breast cancer cells via regulating PDK1/PDHC axis.
Aloe polymeric acemannan inhibits the cytokine storm in mouse pneumonia models by modulating macrophage metabolism.
Lentinan inhibits oxidative stress and alleviates LPS-induced inflammation and apoptosis of BMECs by activating the Nrf2 signaling pathway.
Three water soluble polysaccharides with anti-inflammatory activities from Selaginella uncinata (Desv.) Spring.
Melatonin attenuates bone cancer pain via the SIRT1/HMGB1 pathway.
Minocycline alleviates abnormal microglial phagocytosis of synapses in a mouse model of depression.
USP1 Inhibits NF-κB/NLRP3 Induced Pyroptosis through TRAF6 in Osteoblastic MC3T3-E1 Cells.
YAP1-TEAD1 mediates the perineural invasion of prostate cancer cells induced by cancer-associated fibroblasts.
ACAP1 Deficiency Predicts Inferior Immunotherapy Response in Solid Tumors.
Orphan Nuclear Receptor Nur77 Mediates the Lethal Endoplasmic Reticulum Stress and Therapeutic Efficacy of Cryptomeridiol in Hepatocellular Carcinoma.
Chitosan-Gelatin-EGCG Nanoparticle-Meditated LncRNA TMEM44-AS1 Silencing to Activate the P53 Signaling Pathway for the Synergistic Reversal of 5-FU Resistance in Gastric Cancer.
4-hydroxybenzophenone exposure inhibits mouse hippocampal neural stem cell proliferation in vitro by upregulating Cxcl1.
HIIT and MICT attenuate high-fat diet-induced hepatic lipid accumulation and ER stress via the PERK-ATF4-CHOP signaling pathway.
circNup188/miR-760-3p/Map3k8 axis regulates inflammation in cerebral ischemia.
MELK predicts poor prognosis and promotes metastasis in esophageal squamous cell carcinoma via activating the NF‑κB pathway.
High-Frequency Repetitive Transcranial Magnetic Stimulation Regulates Astrocyte Activation by Modulating the Endocannabinoid System in Parkinson's Disease.
Phosphodiesterase 4D contributes to angiotensin II-induced abdominal aortic aneurysm through smooth muscle cell apoptosis.
Mecheliolide elicits ROS-mediated ERS driven immunogenic cell death in hepatocellular carcinoma.
MicroRNA-30a Targets Notch1 to Alleviate Podocyte Injury in Lupus Nephritis.
Angiotensin receptor-neprilysin inhibitor attenuates cardiac hypertrophy and improves diastolic dysfunction in a mouse model of heart failure with preserved ejection fraction.
Expression and role of miR-146a and SMAD4 in placental tissue of pregnant women with preeclampsia.
Oxidative stress and Cx43-mediated apoptosis are involved in PFOS-induced nephrotoxicity.
EMMPRIN Promotes the Expression of MMP-9 and Exacerbates Neurological Dysfunction in a Mouse Model of Intracerebral Hemorrhage.
The deubiquitinase USP7 regulates oxidative stress through stabilization of HO-1.
TTC22 promotes m6A-mediated WTAP expression and colon cancer metastasis in an RPL4 binding-dependent pattern.
N(6)-methyladenosine (m(6)A) in 18S rRNA promotes fatty acid metabolism and oncogenic transformation.
Homocysteine-Induced Disturbances in DNA Methylation Contribute to Development of Stress-Associated Cognitive Decline in Rats.
MiR-19b-3p promotes tumor progression of non-small cell lung cancer via downregulating HOXA9 and predicts poor prognosis in patients.
Phospho-proteomics identifies a critical role of ATF2 in pseudorabies virus replication.
A novel natural-derived tilapia skin collagen mineralized with hydroxyapatite as a potential bone-grafting scaffold.
l-Arginine prevents 4-hydroxy-2-nonenal accumulation and depresses inflammation via inhibiting NF-κB activation.
VEGF promotes tendon regeneration of aged rats by inhibiting adipogenic differentiation of tendon stem/progenitor cells and promoting vascularization.
Ultraviolet light induces HERV expression to activate RIG-I signalling pathway in keratinocytes.
A WWP2-PTEN-KLF5 signaling axis regulates odontoblast differentiation and dentinogenesis in mice.
IKBKE phosphorylates and stabilizes Snail to promote breast cancer invasion and metastasis.
Brief exposure to directionally-specific pulsed electromagnetic fields stimulates extracellular vesicle release and is antagonized by streptomycin: A potential regenerative medicine and food industry paradigm.
Ferrostatin‑1 alleviates oxalate‑induced renal tubular epithelial cell injury, fibrosis and calcium oxalate stone formation by inhibiting ferroptosis.
MgIG exerts therapeutic effects on crizotinib-induced hepatotoxicity by limiting ROS-mediated autophagy and pyroptosis.
Curcumin attenuates vascular calcification via the exosomal miR-92b-3p/KLF4 axis.
N6-methyladenosine demethylase FTO regulates inflammatory cytokine secretion and tight junctions in retinal pigment epithelium cells.
METTL3 preferentially enhances non-m(6)A translation of epigenetic factors and promotes tumourigenesis.
Paeoniflorin-6'O-benzene sulfonate suppresses fibroblast-like synoviocytes proliferation and migration in rheumatoid arthritis through regulating GRK2-Gβγ interaction.
miR-29b-3p inhibits 22Rv1 prostate cancer cell proliferation through the YWHAE/BCL-2 regulatory axis.
Identification and verification of the role of crucial genes through which methionine restriction inhibits the progression of colon cancer cells.
Nav1.6 promotes the progression of human follicular thyroid carcinoma cells via JAK-STAT signaling pathway.
Pannexin1 inhibits autophagy of cisplatin-resistant testicular cancer cells by mediating ATP release.
Melatonin inhibits angiotensin II-induced atrial fibrillation through preventing degradation of Ang II Type I Receptor-Associated Protein (ATRAP).
Zedoarondiol inhibits atherosclerosis by regulating monocyte migration and adhesion via CXCL12/CXCR4 pathway.
Quercetin encapsulated in folic acid-modified liposomes is therapeutic against osteosarcoma by non-covalent binding to the JH2 domain of JAK2 Via the JAK2-STAT3-PDL1.
Cullin-associated and neddylation-dissociated 1 protein (CAND1) governs cardiac hypertrophy and heart failure partially through regulating calcineurin degradation.
TMEM41B and VMP1 modulate cellular lipid and energy metabolism for facilitating dengue virus infection.
Autophagy regulates differentiation of ovarian granulosa cells through degradation of WT1.
Inhibitory activity and mechanism of silver nanoparticles against herpes simplex virus type 1.
Oxyberberine, a novel HO-1 agonist, effectively ameliorates oxidative stress and inflammatory response in LPS/D-GalN induced acute liver injury mice via coactivating erythrocyte metabolism and Nrf2 signaling pathway.
FXR deficiency in hepatocytes disrupts the bile acid homeostasis and inhibits autophagy to promote liver injury in Schistosoma japonicum-infected mice.
Polyisocyanide hydrogels with tunable nonlinear elasticity mediate liver carcinoma cell functional response.
Hirudo verbana as a freshwater invertebrate model to assess the effects of polypropylene micro and nanoplastics dispersion in freshwater.
HDAC5, negatively regulated by miR-148a-3p, promotes colon cancer cell migration.
Anti-proliferation and apoptosis-inducing effects of dihydroartemisinin on SH-SY5Y cells and metabolomic analysis.
The surface morphology of Platycodon grandiflorus polysaccharide and its anti-apoptotic effect by targeting autophagy.
Morroniside, a novel GATA3 binding molecule, inhibits hepatic stellate cells activation by enhancing lysosomal acid lipase expression.
The Etv1/Er81 transcription factor coordinates myelination-related genes to regulate Schwann cell differentiation and myelination.
Overexpression of integrin β(2) improves migration and engraftment of adipose-derived stem cells and augments angiogenesis in myocardial infarction.
Phosphorylated STYK1 restrains the inhibitory role of EGFR in autophagy initiation and EGFR-TKIs sensitivity.
Deletion of Meg8-DMR Enhances Migration and Invasion of MLTC-1 Depending on the CTCF Binding Sites.
Lidocaine Inhibited Tendon Cell Proliferation and Extracellular Matrix Production by Down Regulation of Cyclin A, CDK2, Type I and Type III Collagen Expression.
PCGF6 controls neuroectoderm specification of human pluripotent stem cells by activating SOX2 expression.
Synthesis and anticancer evaluations of novel 1H-imidazole [4,5-f][1,10] phenanthroline derivative for the treatment of colorectal cancer.
The mechanism of the imbalance between proliferation and ferroptosis in pulmonary artery smooth muscle cells based on the activation of SLC7A11.
Inhibition of Kruppel-like factor 7 attenuates cell proliferation and inflammation of fibroblast-like synoviocytes in rheumatoid arthritis through nuclear factor κB and mitogen-activated protein kinase signaling pathway.
Design, synthesis, and in vitro protective effect evaluation of α-carboline derivatives against H(2)O(2)-induced cardiomyocyte injury.
Metabolic reprogramming from glycolysis to fatty acid uptake and beta-oxidation in platinum-resistant cancer cells.
Deficiency of WTAP in hepatocytes induces lipoatrophy and non-alcoholic steatohepatitis (NASH).
Myocardium-Targeted Micelle Nanomedicine That Salvages the Heart from Ischemia/Reperfusion Injury.
Deep Sequencing of HPV16 E6 Region Reveals Unique Mutation Pattern of HPV16 and Predicts Cervical Cancer.
p53 Binding Sites in Long Terminal Repeat 5Hs (LTR5Hs) of Human Endogenous Retrovirus K Family (HML-2 Subgroup) Play Important Roles in the Regulation of LTR5Hs Transcriptional Activity.
A high-concentrate diet provokes inflammatory responses by downregulating Forkhead box protein A2 (FOXA2) through epigenetic modifications in the liver of dairy cows.
S6K1 amplification confers innate resistance to CDK4/6 inhibitors through activating c-Myc pathway in patients with estrogen receptor-positive breast cancer.
"Two-birds-one-stone" colon-targeted nanomedicine treats ulcerative colitis via remodeling immune microenvironment and anti-fibrosis.
IFIT3 and IFIT5 Play Potential Roles in Innate Immune Response of Porcine Pulmonary Microvascular Endothelial Cells to Highly Pathogenic Porcine Reproductive and Respiratory Syndrome Virus.
The Akt Forkhead Box O Transcription Factor Axis Regulates Human Cytomegalovirus Replication.
Motoneurons innervation determines the distinct gene expressions in multinucleated myofibers.
SETDB1 Restrains Endogenous Retrovirus Expression and Antitumor Immunity during Radiotherapy.
Perivascular and endomysial macrophages expressing VEGF and CXCL12 promote angiogenesis in anti-HMGCR immune-mediated necrotizing myopathy.
Targeting clock-controlled gene Nrf2 ameliorates inflammation-induced intervertebral disc degeneration.
Cornuside Is a Potential Agent against Alzheimer's Disease via Orchestration of Reactive Astrocytes.
MiR-659-3p inhibits osteosarcoma progression and metastasis by inhibiting cell proliferation and invasion via targeting SRPK1.
Reorganization of the Landscape of Translated mRNAs in NSUN2-Deficient Cells and Specific Features of NSUN2 Target mRNAs.
Raltitrexed regulates proliferation and apoptosis of HGC-27 cells by upregulating RSK4.
Spindle and Kinetochore-associated Family Genes are Prognostic and Predictive Biomarkers in Hepatocellular Carcinoma.
A yeast-based system to study SARS-CoV-2 Mpro structure and to identify nirmatrelvir resistant mutations.
Discovery of a Novel Small-Molecule Inhibitor Disrupting TRBP-Dicer Interaction against Hepatocellular Carcinoma via the Modulation of microRNA Biogenesis.
PD-1 Suppresses the Osteogenic and Odontogenic Differentiation of Stem Cells from Dental Apical Papilla via Targeting SHP2/NF-κB Axis.
γ-Glutamylcysteine attenuates amyloid-β oligomers-induced neuroinflammation in microglia via blocking NF-κB signaling pathway.
The Janus-faced role of TRPM2-S in retroperitoneal liposarcoma via increasing ROS levels.
Ammonium tetrathiomolybdate triggers autophagy-dependent NRF2 activation in vascular endothelial cells.
Artificial Intelligence-Assisted Bioinformatics, Microneedle, and Diabetic Wound Healing: A "New Deal" of an Old Drug.
Transverse endoplasmic reticulum expansion in hereditary spastic paraplegia corticospinal axons.
ROS triggered local delivery of stealth exosomes to tumors for enhanced chemo/photodynamic therapy.
DNA Origami as a Nanomedicine for Targeted Rheumatoid Arthritis Therapy through Reactive Oxygen Species and Nitric Oxide Scavenging.
HSP27 Attenuates cGAS-Mediated IFN-β Signaling through Ubiquitination of cGAS and Promotes PRV Infection.
The compound losartan cream inhibits scar formation via TGF-β/Smad pathway.
Duodenal-jejunal bypass increases intraduodenal bile acids and upregulates duodenal SIRT1 expression in high-fat diet and streptozotocin-induced diabetic rats.
Neu1 deficiency increases the susceptibility of zebrafish to Edwardsiella piscicida infection via lysosomal dysfunction.
TP53INP2 Contributes to TGF-β2-Induced Autophagy during the Epithelial-Mesenchymal Transition in Posterior Capsular Opacification Development.
Inhibition of the cardiac fibroblast-enriched histone methyltransferase Dot1L prevents cardiac fibrosis and cardiac dysfunction.
HLJ1 amplifies endotoxin-induced sepsis severity by promoting IL-12 heterodimerization in macrophages.
Mesenchymal stem cells protect against TBI-induced pyroptosis in vivo and in vitro through TSG-6.
Enhancement of BCAT2-Mediated Valine Catabolism Stimulates β-Casein Synthesis via the AMPK-mTOR Signaling Axis in Bovine Mammary Epithelial Cells.
The LINC00623/NAT10 signaling axis promotes pancreatic cancer progression by remodeling ac4C modification of mRNA.
Phosphorylation of GluA1-Ser831 by CaMKII Activation in the Caudate and Putamen Is Required for Behavioral Sensitization After Challenge Nicotine in Rats.
Construction of a novel model based on cell-in-cell-related genes and validation of KRT7 as a biomarker for predicting survival and immune microenvironment in pancreatic cancer.
DNA damage-induced paraspeckle formation enhances DNA repair and tumor radioresistance by recruiting ribosomal protein P0.
Salidroside ameliorates orthopedic surgery-induced cognitive dysfunction by activating adenosine 5'-monophosphate-activated protein kinase signaling in mice.
Colchicine alleviates inflammation and improves diastolic dysfunction in heart failure rats with preserved ejection fraction.
12 T high static magnetic field suppresses osteosarcoma cells proliferation by regulating intracellular ROS and iron status.
CoQ10 Improves Myocardial Damage in Doxorubicin-Induced Heart Failure in C57BL/6 Mice.
Involvement of retinoic acid receptor α in the autistic-like behavior of rats with vitamin A deficiency by regulating neurexin 1 in the visual cortex: a mechanism study.
Hyperphosphorylated tau mediates neuronal death by inducing necroptosis and inflammation in Alzheimer's disease.
PAGln, an Atrial Fibrillation-Linked Gut Microbial Metabolite, Acts as a Promoter of Atrial Myocyte Injury.
CD147 mediates epidermal malignant transformation through the RSK2/AP-1 pathway.
Intra-amniotic transplantation of brain-derived neurotrophic factor-modified mesenchymal stem cells treatment for rat fetuses with spina bifida aperta.
Inert Pepper aptamer-mediated endogenous mRNA recognition and imaging in living cells.
A co-crystal berberine-ibuprofen improves obesity by inhibiting the protein kinases TBK1 and IKKɛ.
Comprehensive analysis of RNA m6A methylation in pressure overload-induced cardiac hypertrophy.
Hsp70 Inhibits the Replication of Fowl Adenovirus Serotype 4 by Suppressing Viral Hexon with the Assistance of DnaJC7.
DMTHB ameliorates memory impairment in Alzheimer's disease mice through regulation of neuroinflammation.
PDE4D binds and interacts with YAP to cooperatively promote HCC progression.
Jianpi Huayu decoction inhibits the epithelial-mesenchymal transition of hepatocellular carcinoma cells by suppressing exosomal miR-23a-3p/Smad signaling.
Penthorum chinense Pursh. extract attenuates non-alcholic fatty liver disease by regulating gut microbiota and bile acid metabolism in mice.
Covalent Organic Framework (COF): A Drug and Carrier to Attenuate Retinal Ganglion Cells Death in an Acute Glaucoma Mouse Model.
MAB21L1 promotes survival of lens epithelial cells through control of αB-crystallin and ATR/CHK1/p53 pathway.
PREX1 depletion ameliorates high-fat diet-induced non-alcoholic fatty liver disease in mice and mitigates palmitic acid-induced hepatocellular injury via suppressing the NF-κB signaling pathway.
Lysosome docking to WIPI1 rings and ER-connected phagophores occurs during DNAJB12- and GABARAP-dependent selective autophagy of misfolded P23H-rhodopsin.
Regulatory roles of fibronectin and integrin α5 in reorganization of the actin cytoskeleton and completion of adipogenesis.
Polycystin-2 (PC2) is a key determinant of in vitro myogenesis.
Cinnamaldehyde protects against ligature-induced periodontitis through the inhibition of microbial accumulation and inflammatory responses of host immune cells.
Shen Shuai Ⅱ Recipe attenuates renal fibrosis in chronic kidney disease by improving hypoxia-induced the imbalance of mitochondrial dynamics via PGC-1α activation.
Urolithin A attenuates arsenic-induced gut barrier dysfunction.
HTR1A Inhibits the Progression of Triple-Negative Breast Cancer via TGF-β Canonical and Noncanonical Pathways.
Elevated RAP1A expression correlates with the severity of acute GVHD after umbilical cord blood transplantation.
Basic fibroblast growth factor inhibits aortic valvular interstitial cells calcification via Notch1 pathway.
Generation of a heterozygous SCN5A knockout human induced pluripotent stem cell line by CRISPR/Cas9 edition.
LncRNA HOTAIR promotes proliferation and suppresses apoptosis of mouse spermatogonium GC-1 cells by sponging miR-761 to modulate NANOS2 expression.
Grem1 accelerates nucleus pulposus cell apoptosis and intervertebral disc degeneration by inhibiting TGF-β-mediated Smad2/3 phosphorylation.
High expression of NPM1 via the Wnt/β-catenin signalling pathway might predict poor prognosis for patients with prostate adenocarcinoma.
Autophagy modulation in resveratrol protective effects on steroidogenesis in high-fat diet-fed mice and H(2)O(2)-challenged TM3 cells.
Midkine promotes breast cancer cell proliferation and migration by upregulating NR3C1 expression and activating the NF-κB pathway.
Trichostatin A inhibits dendritic cell maturation through down-regulating NF-κ B (p65) pathway.
Metformin inhibits pulmonary artery smooth muscle cell proliferation by upregulating p21 via NONRATT015587.2.
Alda-1, an Aldehyde Dehydrogenase 2 Agonist, Improves Cutaneous Wound Healing by Activating Epidermal Keratinocytes via Akt/GSK-3β/β-Catenin Pathway.
Atractylenolide II inhibits tumor-associated macrophages (TAMs)-induced lung cancer cell metastasis.
Baicalin inhibits inflammation of lipopolysaccharide-induced acute lung injury toll like receptor-4/myeloid differentiation primary response 88/nuclear factor-kappa B signaling pathway.
Downregulation of FAPP2 gene induces cell autophagy and inhibits PI3K/AKT/mTOR pathway in T-cell acute lymphoblastic leukemia.
Interleukin-17A mediates tobacco smoke-induced lung cancer epithelial-mesenchymal transition through transcriptional regulation of ΔNp63α on miR-19.
Effects of bone marrow-derived mesenchymal stem cells on doxorubicin-induced liver injury in rats.
The fungal Clitocybe nebularis lectin binds distinct cell surface glycoprotein receptors to induce cell death selectively in Jurkat cells.
Enzyme-instructed self-assembly of peptide-drug conjugates in tear fluids for ocular drug delivery.
EGFR signaling promotes nuclear translocation of plasma membrane protein TSPAN8 to enhance tumor progression via STAT3-mediated transcription.
Angiogenic factor AGGF1 blocks neointimal formation after vascular injury via interaction with integrin α7 on vascular smooth muscle cells.
CircPAPPA Regulates the Proliferation, Migration, Invasion, Apoptosis, and Cell Cycle of Trophoblast Cells Through the miR-3127-5p/HOXA7 Axis.
LncRNA SNHG16 promotes colorectal cancer cell proliferation, migration, and epithelial-mesenchymal transition through miR-124-3p/MCP-1.
FAK regulates cardiomyocyte mitochondrial fission and function through Drp1.
The tyrosine phosphatase PTPN14 inhibits the activation of STAT3 in PEDV infected Vero cells.
Inhibition of RUNX1 blocks the differentiation of lung fibroblasts to myofibroblasts.
The plasma membrane H(+) -ATPase FgPMA1 regulates the development, pathogenicity, and phenamacril sensitivity of Fusarium graminearum by interacting with FgMyo-5 and FgBmh2.
Tumor-promoting mechanisms of macrophage-derived extracellular vesicles-enclosed microRNA-660 in breast cancer progression.
Deubiquitinase-targeting chimeras for targeted protein stabilization.
Phytohormone abscisic acid ameliorates neuropathic pain via regulating LANCL2 protein abundance and glial activation at the spinal cord.
Inhibition of DNA methylation de-represses peroxisome proliferator-activated receptor-γ and attenuates pulmonary fibrosis.
Aberrant epigenetic regulation of RARβ by TET2 is involved in cutaneous squamous cell carcinoma resistance to retinoic acid.
EZH2 Inhibitor Enhances the STING Agonist‒Induced Antitumor Immunity in Melanoma.
Kruppel like factor 16 promotes lung adenocarcinoma progression by upregulating lamin B2.
CircMCTP2 (has-circ-0000658) facilitates the proliferation and metastasis of bladder carcinoma through modulating the miR-498/murine double minute-2 axis.
CircMYC promotes proliferation, migration, invasion and inhibits apoptosis of small cell lung cancer by targeting miR-145/ Matrix Metallopeptidase 2 axis.
Cigarette smoke-induced oxidative stress activates NRF2 to mediate fibronectin disorganization in vascular formation.
Galectin-3 promotes calcification of human aortic valve interstitial cells via the NF-kappa B signaling pathway.
ECSIT inhibits cell death to increase tumor progression and metastasis via p53 in human breast cancer.
Study of novel NARS2 variants in patient of combined oxidative phosphorylation deficiency 24.
LncRNA GAS5 regulates migration and epithelial-to-mesenchymal transition in lens epithelial cells via the miR-204-3p/TGFBR1 axis.
Downregulated ALKBH5 contributes to myocardial ischemia/reperfusion injury by increasing m(6)A modification of Trio mRNA.
A hierarchical bilayer architecture for complex tissue regeneration.
Drug-peptide supramolecular hydrogel boosting transcorneal permeability and pharmacological activity via ligand-receptor interaction.
Low-metastatic melanoma cells acquire enhanced metastatic capability via exosomal transfer of miR-199a-1-5p from highly metastatic melanoma cells.
The m6A demethylase ALKBH5 promotes tumor progression by inhibiting RIG-I expression and interferon alpha production through the IKKε/TBK1/IRF3 pathway in head and neck squamous cell carcinoma.
USP26 promotes anaplastic thyroid cancer progression by stabilizing TAZ.
Elevated FAM84B promotes cell proliferation via interacting with NPM1 in esophageal squamous cell carcinoma.
Mechanosensitive Piezo1 channels mediate renal fibrosis.
Aldehyde dehydrogenase 2 and PARP1 interaction modulates hepatic HDL biogenesis by LXRα-mediated ABCA1 expression.
Transportin-3 Facilitates Uncoating of Influenza A Virus.
Mechanism exploration of ancient pharmaceutic processing (Paozhi) improving the gastroprotective efficacy of Aucklandiae Radix.
SIX5-activated LINC01468 promotes lung adenocarcinoma progression by recruiting SERBP1 to regulate SERPINE1 mRNA stability and recruiting USP5 to facilitate PAI1 protein deubiquitylation.
DELE1 tracks perturbed protein import and processing in human mitochondria.
PT109, a novel multi-kinase inhibitor suppresses glioblastoma multiforme through cell reprogramming: Involvement of PTBP1/PKM1/2 pathway.
GSK-3β-mediated activation of NLRP3 inflammasome leads to pyroptosis and apoptosis of rat cardiomyocytes and fibroblasts.
Pdcd4 promotes lipid deposition by attenuating PPARα-mediated fatty acid oxidation in hepatocytes.
Augmin-dependent microtubule self-organization drives kinetochore fiber maturation in mammals.
KLF5 inhibition overcomes oxaliplatin resistance in patient-derived colorectal cancer organoids by restoring apoptotic response.
Rhoifolin from Plumula Nelumbinis exhibits anti-cancer effects in pancreatic cancer via AKT/JNK signaling pathways.
FMNL2 suppresses cell migration and invasion of breast cancer: a reduction of cytoplasmic p27 via RhoA/LIMK/Cofilin pathway.
TGF-β-induced CCR8 promoted macrophage transdifferentiation into myofibroblast-like cells.
Dexamethasone induces ferroptosis via P53/SLC7A11/GPX4 pathway in glucocorticoid-induced osteonecrosis of the femoral head.
Baclofen attenuates cognitive deficits in post-cardiac arrest brain injury.
Cdh1 Deficiency Sensitizes TNBC Cells to PARP Inhibitors.
3,3'-Diindolylmethane Enhances Fluorouracil Sensitivity via Inhibition of Pyrimidine Metabolism in Colorectal Cancer.
Asymmetric Pericentrosomal CD133 Endosomes Induce the Unequal Autophagic Activity During Cytokinesis in CD133-Positive Human Neuroblastoma Cells.
HOXC6 impacts epithelial-mesenchymal transition and the immune microenvironment through gene transcription in gliomas.
Trappc9 Deficiency Impairs the Plasticity of Stem Cells.
Map of Enteropathogenic Escherichia coli Targets Mitochondria and Triggers DRP-1-Mediated Mitochondrial Fission and Cell Apoptosis in Bovine Mastitis.
Grape-Seed-Derived Procyanidin Attenuates Chemotherapy-Induced Cognitive Impairment by Suppressing MMP-9 Activity and Related Blood-Brain-Barrier Damage.
KRT17 Promotes the Activation of HSCs via EMT in Liver Fibrosis.
Ferrous Bisglycinate Supplementation Modulates Intestinal Antioxidant Capacity via the AMPK/FOXO Pathway and Reconstitutes Gut Microbiota and Bile Acid Profiles in Pigs.
High altitude is associated with pTau deposition, neuroinflammation, and myelin loss.
MiR-145 modulates the radiosensitivity of non-small cell lung cancer cells by suppression of TMOD3.
Trans-cinnamaldehyde protects against phenylephrine-induced cardiomyocyte hypertrophy through the CaMKII/ERK pathway.
Engineered Cas12a-Plus nuclease enables gene editing with enhanced activity and specificity.
TMT-based proteomics analysis of the cerebral cortex of TauT knockout rats.
Ageing related thyroid deficiency increases brain-targeted transport of liver-derived ApoE4-laden exosomes leading to cognitive impairment.
The organic cation transporter 2 regulates dopamine D1 receptor signaling at the Golgi apparatus.
Mechanical Load and Piezo1 Channel Regulated Myosin II Activity in Mouse Lenses.
Exercise activates autophagy and regulates endoplasmic reticulum stress in muscle of high-fat diet mice to alleviate insulin resistance.
GALNT8 suppresses breast cancer cell metastasis potential by regulating EGFR O-GalNAcylation.
Targeting DRD2 by the antipsychotic drug, penfluridol, retards growth of renal cell carcinoma via inducing stemness inhibition and autophagy-mediated apoptosis.
Ziprasidone Induces Rabbit Atrium Arrhythmogenesis via Modification of Oxidative Stress and Sodium/Calcium Homeostasis.
p97/UBXD1 Generate Ubiquitylated Proteins That Are Sequestered into Nuclear Envelope Herniations in Torsin-Deficient Cells.
[Identification of microRNAs targeting vitamin D receptor and their effect on parathyroid hormone secretion in secondary hyperparathyroidism].
Exosomal miR-146a-5p and miR-155-5p promote CXCL12/CXCR7-induced metastasis of colorectal cancer by crosstalk with cancer-associated fibroblasts.
Suppression of premature transcription termination leads to reduced mRNA isoform diversity and neurodegeneration.
Predict the role of lncRNA in kidney aging based on RNA sequencing.
Tanshinone I attenuates fibrosis in fibrotic kidneys through down-regulation of inhibin beta-A.
Regulatory variants at 2q33.1 confer schizophrenia risk by modulating distal gene TYW5 expression.
Pcsk6 Deficiency Promotes Cardiomyocyte Senescence by Modulating Ddit3-Mediated ER Stress.
Loss of serine/threonine protein kinase 25 in retinal ganglion cells ameliorates high glucose-elicited damage through regulation of the AKT-GSK-3β/Nrf2 pathway.
Paeonol protects against acute pancreatitis by inhibiting M1 macrophage polarization via the NLRP3 inflammasomes pathway.
Caveolae promote successful abscission by controlling intercellular bridge tension during cytokinesis.
Human umbilical cord mesenchymal stem cell-derived exosomal microRNA-148a-3p inhibits neointimal hyperplasia by targeting Serpine1.
ELAV-like RNA binding protein 1 regulates osteogenesis in diabetic osteoporosis: Involvement of divalent metal transporter 1.
GDAP2 Overexpression Affects the Development of Neurons and Dysregulates Neuronal Excitatory Synaptic Transmission.
Cytochalasin Q exerts anti-melanoma effect by inhibiting creatine kinase B.
Silencing of Nudix type 5 represses proliferation and invasion and enhances chemosensitivity of gastric carcinoma cells by affecting the AKT/GSK-3β/β-catenin pathway.
ILF3 represses repeat-derived microRNAs targeting RIG-I mediated type I interferon response.
Linkage of methionine addiction, histone lysine hypermethylation, and malignancy.
New Cases of Hypochromic Microcytic Anemia Due to Mutations in the SLC11A2 Gene and Functional Characterization of the G75R Mutation.
Substrate stiffness regulates differentiation of induced pluripotent stem cells into heart valve endothelial cells.
EGFR/MET promotes hepatocellular carcinoma metastasis by stabilizing tumor cells and resisting to RTKs inhibitors in circulating tumor microemboli.
SNORD1C maintains stemness and 5-FU resistance by activation of Wnt signaling pathway in colorectal cancer.
The dynamic alteration of transcriptional regulation by crucial TFs during tumorigenesis of gastric cancer.
Selective sorting and secretion of hY4 RNA fragments into extracellular vesicles mediated by methylated YBX1 to promote lung cancer progression.
Benzo(a)pyrene induces airway epithelial injury through Wnt5a-mediated non-canonical Wnt-YAP/TAZ signaling.
Microcystin-leucine arginine (MC-LR) induces mouse ovarian inflammation by promoting granulosa cells to produce inflammatory cytokine via activation of cGAS-STING signaling.
Antiviral Effects of ABMA and DABMA against Influenza Virus In Vitro and In Vivo via Regulating the Endolysosomal Pathway and Autophagy.
Systematic Survey of the Regulatory Networks of the Long Noncoding RNA BANCR in Cervical Cancer Cells.
Platelet-derived microvesicles regulate vascular smooth muscle cell energy metabolism via PRKAA after intimal injury.
Sec13 promotes oligodendrocyte differentiation and myelin repair through autocrine pleiotrophin signaling.
miR-142a-3p Enhances FlaA N/C Protection Against Radiation-Mediated Intestinal Injury by Modulating the IRAK1/NF-κB Signaling Pathway.
A novel role for apatinib in enhancing radiosensitivity in non-small cell lung cancer cells by suppressing the AKT and ERK pathways.
Identification and validation of candidate genes dysregulated in alveolar macrophages of acute respiratory distress syndrome.
N-acetyl-L-tryptophan attenuates hepatic ischemia-reperfusion injury via regulating TLR4/NLRP3 signaling pathway in rats.
Involvement of plasminogen activator inhibitor-1 and its related molecules in atrial fibrosis in patients with atrial fibrillation.
Identification of potential genes in upper tract urothelial carcinoma using next-generation sequencing with bioinformatics and in vitro analyses.
Melatonin ameliorates myocardial injury by reducing apoptosis and autophagy of cardiomyocytes in a rat cardiopulmonary bypass model.
Long non-coding RNA taurine upregulated gene 1 is downregulated in osteoporosis and influences the osteogenic differentiation of bone marrow mesenchymal stem cells.
Screening and identification of endometrial proteins as novel potential biomarkers for repeated implantation failure.
Human Umbilical Cord Mesenchymal Stem Cells Improve Locomotor Function in Parkinson's Disease Mouse Model Through Regulating Intestinal Microorganisms.
TMAO-Activated Hepatocyte-Derived Exosomes Impair Angiogenesis via Repressing CXCR4.
p53-Induced LINC00893 Regulates RBFOX2 Stability to Suppress Gastric Cancer Progression.
SCG2 is a Prognostic Biomarker Associated With Immune Infiltration and Macrophage Polarization in Colorectal Cancer.
Midkine Prevents Calcification of Aortic Valve Interstitial Cells via Intercellular Crosstalk.
Harmine Alleviated Sepsis-Induced Cardiac Dysfunction by Modulating Macrophage Polarization via the STAT/MAPK/NF-κB Pathway.
m6A Modification-Mediated DUXAP8 Regulation of Malignant Phenotype and Chemotherapy Resistance of Hepatocellular Carcinoma Through miR-584-5p/MAPK1/ERK Pathway Axis.
Keratin 17 Is Required for Lipid Metabolism in Keratinocytes and Benefits Epidermal Permeability Barrier Homeostasis.
OPA1 Modulates Mitochondrial Ca(2+) Uptake Through ER-Mitochondria Coupling.
Curdione and Schisandrin C Synergistically Reverse Hepatic Fibrosis via Modulating the TGF-β Pathway and Inhibiting Oxidative Stress.
Oncogenic Activation of YAP Signaling Sensitizes Ferroptosis of Hepatocellular Carcinoma via ALOXE3-Mediated Lipid Peroxidation Accumulation.
IL-18-Mediated SLC7A5 Overexpression Enhances Osteogenic Differentiation of Human Bone Marrow Mesenchymal Stem Cells via the c-MYC Pathway.
PPARγ/SOD2 Protects Against Mitochondrial ROS-Dependent Apoptosis via Inhibiting ATG4D-Mediated Mitophagy to Promote Pancreatic Cancer Proliferation.
Platelet-Derived Microvesicles Promote VSMC Dedifferentiation After Intimal Injury via Src/Lamtor1/mTORC1 Signaling.
An Advanced Systems Pharmacology Strategy Reveals AKR1B1, MMP2, PTGER3 as Key Genes in the Competing Endogenous RNA Network of Compound Kushen Injection Treating Gastric Carcinoma by Integrated Bioinformatics and Experimental Verification.
Reducing Inflammation and Vascular Invasion in Intervertebral Disc Degeneration via Cystathionine-γ-Lyase Inhibitory Effect on E-Selectin.
PBX1 Attenuates Hair Follicle-Derived Mesenchymal Stem Cell Senescence and Apoptosis by Alleviating Reactive Oxygen Species-Mediated DNA Damage Instead of Enhancing DNA Damage Repair.
PINK1 Alleviates Cognitive Impairments via Attenuating Pathological Tau Aggregation in a Mouse Model of Tauopathy.
Increased Nuclear Transporter Importin 7 Contributes to the Tumor Growth and Correlates With CD8 T Cell Infiltration in Cervical Cancer.
LncRNA RNA Component of Mitochondrial RNA-Processing Endoribonuclease Promotes AKT-Dependent Breast Cancer Growth and Migration by Trapping MicroRNA-206.
PRDM16 Inhibits Cell Proliferation and Migration via Epithelial-to-Mesenchymal Transition by Directly Targeting Pyruvate Carboxylase in Papillary Thyroid Cancer.
Macrophage-Mediated Bone Formation in Scaffolds Modified With MSC-Derived Extracellular Matrix Is Dependent on the Migration Inhibitory Factor Signaling Pathway.
Depletion of Demethylase KDM6 Enhances Early Neuroectoderm Commitment of Human PSCs.
Design, Synthesis, and Biological Evaluation of Pyrano[2,3-c]-pyrazole-Based RalA Inhibitors Against Hepatocellular Carcinoma.
Cardiac Overexpression of XIN Prevents Dilated Cardiomyopathy Caused by TNNT2 ΔK210 Mutation.
LncRNA CRNDE Promotes ATG4B-Mediated Autophagy and Alleviates the Sensitivity of Sorafenib in Hepatocellular Carcinoma Cells.
GDF11 Alleviates Pathological Myocardial Remodeling in Diabetic Cardiomyopathy Through SIRT1-Dependent Regulation of Oxidative Stress and Apoptosis.
SUN5 Interacting With Nesprin3 Plays an Essential Role in Sperm Head-to-Tail Linkage: Research on Sun5 Gene Knockout Mice.
Autophagy-Related LC3 Accumulation Interacted Directly With LIR Containing RIPK1 and RIPK3, Stimulating Necroptosis in Hypoxic Cardiomyocytes.
Quiescin Sulfhydryl Oxidase 2 Overexpression Predicts Poor Prognosis and Tumor Progression in Patients With Colorectal Cancer: A Study Based on Data Mining and Clinical Verification.
NudC L279P Mutation Destabilizes Filamin A by Inhibiting the Hsp90 Chaperoning Pathway and Suppresses Cell Migration.
Exosomal miR-2276-5p in Plasma Is a Potential Diagnostic and Prognostic Biomarker in Glioma.
Comprehensive Analysis of the Transcriptome-Wide m6A Methylome in Pterygium by MeRIP Sequencing.
α-Enolase Lies Downstream of mTOR/HIF1α and Promotes Thyroid Carcinoma Progression by Regulating CST1.
Force-Induced Autophagy in Periodontal Ligament Stem Cells Modulates M1 Macrophage Polarization via AKT Signaling.
SP1-Mediated Upregulation of Long Noncoding RNA ZFAS1 Involved in Non-syndromic Cleft Lip and Palate via Inactivating WNT/β-Catenin Signaling Pathway.
NLGN3 Upregulates Expression of ADAM10 to Promote the Cleavage of NLGN3 via Activating the LYN Pathway in Human Gliomas.
The E3 Ligase PIAS1 Regulates p53 Sumoylation to Control Stress-Induced Apoptosis of Lens Epithelial Cells Through the Proapoptotic Regulator Bax.
Platelet-Rich Plasma Induces Autophagy and Promotes Regeneration in Human Dental Pulp Cells.
BRD7 Promotes Cell Proliferation and Tumor Growth Through Stabilization of c-Myc in Colorectal Cancer.
BMSC-Derived Small Extracellular Vesicles Induce Cartilage Reconstruction of Temporomandibular Joint Osteoarthritis via Autotaxin-YAP Signaling Axis.
LINC00511/miRNA-143-3p Modulates Apoptosis and Malignant Phenotype of Bladder Carcinoma Cells via PCMT1.
Urea as a By-Product of Ammonia Metabolism Can Be a Potential Serum Biomarker of Hepatocellular Carcinoma.
Inhibition of JAK-STAT Signaling Pathway Alleviates Age-Related Phenotypes in Tendon Stem/Progenitor Cells.
β-Arrestin1 Promotes Colorectal Cancer Metastasis Through GSK-3β/β-Catenin Signaling- Mediated Epithelial-to-Mesenchymal Transition.
Cartilage Endplate Stem Cells Transdifferentiate Into Nucleus Pulposus Cells via Autocrine Exosomes.
CORO6 Promotes Cell Growth and Invasion of Clear Cell Renal Cell Carcinoma via Activation of WNT Signaling.
TAp63α Is Involved in Tobacco Smoke-Induced Lung Cancer EMT and the Anti-cancer Activity of Curcumin via miR-19 Transcriptional Suppression.
Hypoxia-Induced LIN28A mRNA Promotes the Metastasis of Colon Cancer in a Protein-Coding-Independent Manner.
A Novel CpG Methylation Risk Indicator for Predicting Prognosis in Bladder Cancer.
Exosomal miR-3682-3p Suppresses Angiogenesis by Targeting ANGPT1 via the RAS-MEK1/2-ERK1/2 Pathway in Hepatocellular Carcinoma.
Establishment of an Efficient Primary Culture System for Human Hair Follicle Stem Cells Using the Rho-Associated Protein Kinase Inhibitor Y-27632.
Grb2 Induces Cardiorenal Syndrome Type 3: Roles of IL-6, Cardiomyocyte Bioenergetics, and Akt/mTOR Pathway.
Extracellular Vesicles Carry lncRNA SNHG16 to Promote Metastasis of Breast Cancer Cells via the miR-892b/PPAPDC1A Axis.
The Protective Effect of 1,25(OH)(2)D(3) on Myocardial Function is Mediated via Sirtuin 3-Regulated Fatty Acid Metabolism.
LUZP1 Controls Cell Division, Migration and Invasion Through Regulation of the Actin Cytoskeleton.
High-Fat Diet Induced Gut Microbiota Alterations Associating With Ghrelin/Jak2/Stat3 Up-Regulation to Promote Benign Prostatic Hyperplasia Development.
Hypoglycemic Efficacy of Rh-aFGF Variants in Treatment of Diabetes in ZDF Rats.
Deficiency of Sirtuin 1 Impedes Endometrial Decidualization in Recurrent Implantation Failure Patients.
Retinoic Acid Signaling Plays a Crucial Role in Excessive Caffeine Intake-Disturbed Apoptosis and Differentiation of Myogenic Progenitors.
MNSFβ Promotes the Proliferation and Migration of Human Extravillous Trophoblast Cells and the Villus Expression Level of MNSFβ Is Decreased in Recurrent Miscarriage Patients.
Rutaecarpine Inhibits Doxorubicin-Induced Oxidative Stress and Apoptosis by Activating AKT Signaling Pathway.
JMJD1A/NR4A1 Signaling Regulates the Procession of Renal Tubular Epithelial Interstitial Fibrosis Induced by AGEs in HK-2.
Characterization of an Aging-Based Diagnostic Gene Signature and Molecular Subtypes With Diverse Immune Infiltrations in Atherosclerosis.
Sirt1 Promotes the Restoration of Hepatic Progenitor Cell (HPC)-Mediated Liver Fatty Injury in NAFLD Through Activating the Wnt/β-Catenin Signal Pathway.
NAP1L5 Promotes Nucleolar Hypertrophy and Is Required for Translation Activation During Cardiomyocyte Hypertrophy.
Validated Impacts of N6-Methyladenosine Methylated mRNAs on Apoptosis and Angiogenesis in Myocardial Infarction Based on MeRIP-Seq Analysis.
MAP3K8 Is a Prognostic Biomarker and Correlated With Immune Response in Glioma.
Microenvironment Stiffness Amplifies Post-ischemia Heart Regeneration in Response to Exogenous Extracellular Matrix Proteins in Neonatal Mice.
Maslinic Acid Attenuates Ischemia/Reperfusion Injury-Induced Myocardial Inflammation and Apoptosis by Regulating HMGB1-TLR4 Axis.
Vanadium Induces Oxidative Stress and Mitochondrial Quality Control Disorder in the Heart of Ducks.
Development and Validation of Ten-RNA Binding Protein Signature Predicts Overall Survival in Osteosarcoma.
The Role of Sorting Nexin 17 in Cardiac Development.
Single-Cell Profiles of Age-Related Osteoarthritis Uncover Underlying Heterogeneity Associated With Disease Progression.
Methylation and Expression of the Exercise-Related TLR1 Gene Is Associated With Low Grade Glioma Prognosis and Outcome.
Comprehensive Analysis of REST/NRSF Gene in Glioma and Its ceRNA Network Identification.
S-Propargyl-Cysteine Attenuates Diabetic Cardiomyopathy in db/db Mice Through Activation of Cardiac Insulin Receptor Signaling.
Mechanically Activated Calcium Channel PIEZO1 Modulates Radiation-Induced Epithelial-Mesenchymal Transition by Forming a Positive Feedback With TGF-β1.
PIEZO1 Ion Channel Mediates Ionizing Radiation-Induced Pulmonary Endothelial Cell Ferroptosis via Ca(2+)/Calpain/VE-Cadherin Signaling.
Developmental Angiogenesis Requires the Mitochondrial Phenylalanyl-tRNA Synthetase.
Expression of LOX Suggests Poor Prognosis in Gastric Cancer.
MiR-3064 in Epicardial Adipose-Derived Exosomes Targets Neuronatin to Regulate Adipogenic Differentiation of Epicardial Adipose Stem Cells.
Development and Verification of a Hypoxic Gene Signature for Predicting Prognosis, Immune Microenvironment, and Chemosensitivity for Osteosarcoma.
CUX1 Facilitates the Development of Oncogenic Properties Via Activating Wnt/β-Catenin Signaling Pathway in Glioma.
Expression and Functional Analysis of lncRNAs Involved in Platelet-Derived Growth Factor-BB-Induced Proliferation of Human Aortic Smooth Muscle Cells.
Traditional Chinese Medication Qiliqiangxin Attenuates Diabetic Cardiomyopathy via Activating PPARγ.
ZEB1 Mediates Bone Marrow Mesenchymal Stem Cell Osteogenic Differentiation Partly via Wnt/β-Catenin Signaling.
Whole-Transcriptome Analysis of LncRNAs Mediated ceRNA Regulation in Granulosa Cells Isolated From Healthy and Atresia Follicles of Chinese Buffalo.
CRISPR/dCas9-Mediated Parkin Inhibition Impairs Mitophagy and Aggravates Apoptosis of Rat Nucleus Pulposus Cells Under Oxidative Stress.
Pharmacological Activating Transcription Factor 6 Activation Is Beneficial for Liver Retrieval With ex vivo Normothermic Mechanical Perfusion From Cardiac Dead Donor Rats.
Identification of Proteomic Signatures in Chronic Obstructive Pulmonary Disease Emphysematous Phenotype.
WDR45 Mutation Impairs the Autophagic Degradation of Transferrin Receptor and Promotes Ferroptosis.
Antiretroviral Drugs Regulate Epigenetic Modification of Cardiac Cells Through Modulation of H3K9 and H3K27 Acetylation.
Acitretin Promotes the Differentiation of Myeloid-Derived Suppressor Cells in the Treatment of Psoriasis.
Tanshinone IIA Combined With Cyclosporine A Alleviates Lung Apoptosis Induced by Renal Ischemia-Reperfusion in Obese Rats.
CYP2C8 Suppress Proliferation, Migration, Invasion and Sorafenib Resistance of Hepatocellular Carcinoma via PI3K/Akt/p27(kip1) Axis.
Cannabisin D from Sinomenium Acutum Inhibits Proliferation and Migration of Glioblastoma Cells through MAPKs Signaling.
The mechanism and candidate compounds of aged citrus peel (chenpi) preventing chronic obstructive pulmonary disease and its progression to lung cancer.
Disulfiram Chelated with Copper Promotes Apoptosis in Osteosarcoma via ROS/Mitochondria Pathway.
Discovery and Verification of Key Liver Cancer Genes and Alternative Splicing Events Based on Second-Generation Sequencing Data Analysis.
Knockdown of GPSM1 Inhibits the Proliferation and Promotes the Apoptosis of B-Cell Acute Lymphoblastic Leukemia Cells by Suppressing the ADCY6-RAPGEF3-JNK Signaling Pathway.
Suppression of DLBCL Progression by the E3 Ligase Trim35 Is Mediated by CLOCK Degradation and NK Cell Infiltration.
TNPO1-Mediated Nuclear Import of FUBP1 Contributes to Tumor Immune Evasion by Increasing NRP1 Expression in Cervical Cancer.
MiR-21-3p Inhibits Adipose Browning by Targeting FGFR1 and Aggravates Atrial Fibrosis in Diabetes.
PIN1 Protects Hair Cells and Auditory HEI-OC1 Cells against Senescence by Inhibiting the PI3K/Akt/mTOR Pathway.
Lipidomic Alterations and PPARα Activation Induced by Resveratrol Lead to Reduction in Lesion Size in Endometriosis Models.
Y-Box Binding Protein 1 Regulates Angiogenesis in Bladder Cancer via miR-29b-3p-VEGFA Pathway.
Benefit Effect of Dendrobium officinale Ultrafine Powder on DSS-Induced Ulcerative Colitis Rats by Improving Colon Mucosal Barrier.
VIP Stabilizes the Cytoskeleton of Schlemm's Canal Endothelia via Reducing Caspase-3 Mediated ZO-1 Endolysosomal Degradation.
Pan-Cancer Analyses of the Tumor Microenvironment Reveal That Ubiquitin-Conjugating Enzyme E2C Might Be a Potential Immunotherapy Target.
Effect and Mechanism of LRP6 on Cardiac Myocyte Ferroptosis in Myocardial Infarction.
Tetrandrine Ameliorates Myocardial Ischemia Reperfusion Injury through miR-202-5p/TRPV2.
P2X7 Receptor Induces Pyroptotic Inflammation and Cartilage Degradation in Osteoarthritis via NF-κB/NLRP3 Crosstalk.
Oleanolic Acid Induces Autophagy and Apoptosis via the AMPK-mTOR Signaling Pathway in Colon Cancer.
Protective Effect of Xiao-Xu-Ming Decoction-Mediated Inhibition of ROS/NLRP3 Axis on Lipopolysaccharide-Induced Acute Lung Injury In Vitro and In Vivo.
Trophoblasts Modulate the Ca(2+) Oscillation and Contraction of Myometrial Smooth Muscle Cells by Small Extracellular Vesicle- (sEV-) Mediated Exporting of miR-25-3p during Premature Labor.
Functional Analysis of Ectodysplasin-A Mutations in X-Linked Nonsyndromic Hypodontia and Possible Involvement of X-Chromosome Inactivation.
Wenxin Granules Regulate Endoplasmic Reticulum Stress Unfolded Protein Response and Improve Ventricular Remodeling on Rats with Myocardial Infarction.
Limonin Inhibits IL-1β-Induced Inflammation and Catabolism in Chondrocytes and Ameliorates Osteoarthritis by Activating Nrf2.
Trehalose Ameliorates Diabetic Cardiomyopathy: Role of the PK2/PKR Pathway.
Pentoxifylline Can Reduce the Inflammation Caused by LPS after Inhibiting Autophagy in RAW264.7 Macrophage Cells.
RBM23 Drives Hepatocellular Carcinoma by Activating NF-κB Signaling Pathway.
Ganoderma lucidum Spore Polysaccharide Inhibits the Growth of Hepatocellular Carcinoma Cells by Altering Macrophage Polarity and Induction of Apoptosis.
Dendrobium officinale Regulates Fatty Acid Metabolism to Ameliorate Liver Lipid Accumulation in NAFLD Mice.
Nardosinone Alleviates Parkinson's Disease Symptoms in Mice by Regulating Dopamine D2 Receptor.
Ferroportin-Dependent Iron Homeostasis Protects against Oxidative Stress-Induced Nucleus Pulposus Cell Ferroptosis and Ameliorates Intervertebral Disc Degeneration In Vivo.
Melatonin Alleviates Contrast-Induced Acute Kidney Injury by Activation of Sirt3.
Exercise Reduces Morphine-Induced Hyperalgesia and Antinociceptive Tolerance.
Identification of Immune-Related Prognostic Biomarkers Associated with HPV-Positive Head and Neck Squamous Cell Carcinoma.
Tantalum Particles Induced Cytotoxic and Inflammatory Effects in Human Monocytes.
Serum Exosomes Derived from Irritable Bowel Syndrome Patient Increase Cell Permeability via Regulating miR-148b-5p/RGS2 Signaling in Human Colonic Epithelium Cells.
CDK12 Promotes Cervical Cancer Progression through Enhancing Macrophage Infiltration.
Oxalate Activates Autophagy to Induce Ferroptosis of Renal Tubular Epithelial Cells and Participates in the Formation of Kidney Stones.
HO-1/CO Maintains Intestinal Barrier Integrity through NF-κB/MLCK Pathway in Intestinal HO-1(-/-) Mice.
GPX4-Regulated Ferroptosis Mediates S100-Induced Experimental Autoimmune Hepatitis Associated with the Nrf2/HO-1 Signaling Pathway.
MicroRNA Hsa-Let-7b Regulates the Osteogenic Differentiation of Human Periodontal Ligament Stem Cells by Targeting CTHRC1.
RNA-Seq Profiling to Investigate the Mechanism of Qishen Granules on Regulating Mitochondrial Energy Metabolism of Heart Failure in Rats.
Treatment of Radiation Bone Injury with Transplanted hUCB-MSCs via Wnt/β-Catenin.
Babao Dan Reverses Multiple-Drug Resistance in Gastric Cancer Cells via Triggering Apoptosis and Autophagy and Inhibiting PI3K/AKT/mTOR Signaling.
lncRNA HHIP-AS1 Promotes the Osteogenic Differentiation Potential and Inhibits the Migration Ability of Periodontal Ligament Stem Cells.
Tubeimoside I Ameliorates Myocardial Ischemia-Reperfusion Injury through SIRT3-Dependent Regulation of Oxidative Stress and Apoptosis.
Heat Killed Salmonella typhimurium Protects Intestine Against Radiation Injury Through Wnt Signaling Pathway.
Essential Oil-Rich Chinese Formula Luofushan-Baicao Oil Inhibits the Infection of Influenza A Virus through the Regulation of NF-κB P65 and IRF3 Activation.
TIPE1 Suppresses Growth and Metastasis of Ovarian Cancer.
Pleckstrin-2 as a Prognostic Factor and Mediator of Gastric Cancer Progression.
LuQi Formula Regulates NLRP3 Inflammasome to Relieve Myocardial-Infarction-Induced Cardiac Remodeling in Mice.
METTL3-Mediated m(6)A RNA Modification Regulates Corneal Injury Repair.
CKAP2L, as an Independent Risk Factor, Closely Related to the Prognosis of Glioma.
NR1D1 Deletion Induces Rupture-Prone Vulnerable Plaques by Regulating Macrophage Pyroptosis via the NF-κB/NLRP3 Inflammasome Pathway.
Design, Synthesis, and Biological Evaluation of a Novel Aminothiol Compound as Potential Radioprotector.
The Dietary Supplement γ-Oryzanol Attenuates Hepatic Ischemia Reperfusion Injury via Inhibiting Endoplasmic Reticulum Stress and HMGB1/NLRP3 Inflammasome.
Effects of Long Noncoding RNA HOTAIR Targeting miR-138 on Inflammatory Response and Oxidative Stress in Rat Cardiomyocytes Induced by Hypoxia and Reoxygenation.
MCC950, the NLRP3 Inhibitor, Protects against Cartilage Degradation in a Mouse Model of Osteoarthritis.
Hypoxia Enhances Activity and Malignant Behaviors of Colorectal Cancer Cells through the STAT3/MicroRNA-19a/PTEN/PI3K/AKT Axis.
Cox-2 Antagonizes the Protective Effect of Sevoflurane on Hypoxia/Reoxygenation-Induced Cardiomyocyte Apoptosis through Inhibiting the Akt Pathway.
Expression of ANGPTL4 in Nucleus Pulposus Tissues Is Associated with Intervertebral Disc Degeneration.
ULK1 Suppresses Osteoclast Differentiation and Bone Resorption via Inhibiting Syk-JNK through DOK3.
Danhong Injection and Trimetazidine Protect Cardiomyocytes and Enhance Calcium Handling after Myocardial Infarction.
Luteolin Improves Cyclophosphamide-Induced Cystitis through TXNIP/NLRP3 and NF-κB Pathways.
Mitoquinone Protects Podocytes from Angiotensin II-Induced Mitochondrial Dysfunction and Injury via the Keap1-Nrf2 Signaling Pathway.
Ivabradine Ameliorates Cardiac Function in Heart Failure with Preserved and Reduced Ejection Fraction via Upregulation of miR-133a.
circGLI3 Inhibits Oxidative Stress by Regulating the miR-339-5p/VEGFA Axis in IPEC-J2 Cells.
Inhibiting PP2Acα Promotes the Malignant Phenotype of Gastric Cancer Cells through the ATM/METTL3 Axis.
An Integrated Transcriptomics and Proteomics Analysis Implicates lncRNA MALAT1 in the Regulation of Lipid Metabolism.
Lack of WDFY4 Aggravates Ovalbumin-Induced Asthma via Enhanced Th2 Cell Differentiation.
Long noncoding RNA CEBPA-DT promotes cisplatin chemo-resistance through CEBPA/BCL2 mediated apoptosis in oral squamous cellular cancer.
The expression and clinical significance of TPM4 in hepatocellular carcinoma.
Dual-specificity Phosphatase 9 protects against Cardiac Hypertrophy by targeting ASK1.
GABAB receptor inhibits tumor progression and epithelial-mesenchymal transition via the regulation of Hippo/YAP1 pathway in colorectal cancer.
MicroRNA-135b/CAMK2D Axis Contribute to Malignant Progression of Gastric Cancer through EMT Process Remodeling.
NDRG1 regulates Filopodia-induced Colorectal Cancer invasiveness via modulating CDC42 activity.
YY1-modulated long non-coding RNA SNHG12 promotes gastric cancer metastasis by activating the miR-218-5p/YWHAZ axis.
PAK5-mediated AIF phosphorylation inhibits its nuclear translocation and promotes breast cancer tumorigenesis.
Aurka deficiency in the intestinal epithelium promotes age-induced obesity via propionate-mediated AKT activation.
Characteristics of the PI3K/AKT and MAPK/ERK pathways involved in the maintenance of self-renewal in lung cancer stem-like cells.
Novel biomarkers for post-contrast acute kidney injury identified from long non-coding RNA expression profiles.
Linc-KILH potentiates Notch1 signaling through inhibiting KRT19 phosphorylation and promotes the malignancy of hepatocellular carcinoma.
ITGB1 enhances the Radioresistance of human Non-small Cell Lung Cancer Cells by modulating the DNA damage response and YAP1-induced Epithelial-mesenchymal Transition.
Inhibition of PI3K/AKT signaling via ROS regulation is involved in Rhein-induced apoptosis and enhancement of oxaliplatin sensitivity in pancreatic cancer cells.
SOX13/TRIM11/YAP axis promotes the proliferation, migration and chemoresistance of anaplastic thyroid cancer.
MAD2B-mediated cell cycle reentry of podocytes is involved in the pathogenesis of FSGS.
Discovery of a novel HDACi structure that inhibits the proliferation of ovarian cancer cells in vivo and in vitro.
Downregulation of miR‑214-3p attenuates mesangial hypercellularity by targeting PTEN‑mediated JNK/c-Jun signaling in IgA nephropathy.
Genome-scale CRISPRa screening identifies MTX1 as a contributor for sorafenib resistance in hepatocellular carcinoma by augmenting autophagy.
CXCL16 Promotes Gastric Cancer Tumorigenesis via ADAM10-Dependent CXCL16/CXCR6 Axis and Activates Akt and MAPK Signaling Pathways.
Ailanthus Altissima-derived Ailanthone enhances Gastric Cancer Cell Apoptosis by Inducing the Repression of Base Excision Repair by Downregulating p23 Expression.
Novel Functions of CD147 in the Mitochondria Exacerbates Melanoma Metastasis.
COP9 Signalosome Subunit 3 Restricts Neuroinflammatory Responses During Cerebral Ischemia/Reperfusion Injury Through Stabilizing Suppressor of Cytokine Signaling 3 Protein.
Loss of miR-1469 expression mediates melanoma cell migration and invasion.
A novel mouse line with epididymal initial segment-specific expression of Cre recombinase driven by the endogenous Lcn9 promoter.
Modulation of inflammatory responses by fractalkine signaling in microglia.
Harmine inhibits breast cancer cell migration and invasion by inducing the degradation of Twist1.
High expression of ENPP1 in high-grade serous ovarian carcinoma predicts poor prognosis and as a molecular therapy target.
Downregulation of RAB7 and Caveolin-1 increases MMP-2 activity in renal tubular epithelial cells under hypoxic conditions.
Copper Nanoparticles Induce Oxidative Stress via the Heme Oxygenase 1 Signaling Pathway in vitro Studies.
Silica Nanoparticles Promote α-Synuclein Aggregation and Parkinson's Disease Pathology.
Convallatoxin Promotes M2 Macrophage Polarization to Attenuate Atherosclerosis Through PPARγ-Integrin α(v)β(5) Signaling Pathway.
A Novel Hydrogen Sulfide Donor Reduces Pilocarpine-Induced Status Epilepticus and Regulates Microglial Inflammatory Profile.
Astroglial CB1 Cannabinoid Receptors Mediate CP 55,940-Induced Conditioned Place Aversion Through Cyclooxygenase-2 Signaling in Mice.
Astrocyte Pannexin 1 Suppresses LPS-Induced Inflammatory Responses to Protect Neuronal SH-SY5Y Cells.
Tetramethylpyrazine Alleviates Behavioral and Psychological Symptoms of Dementia Through Facilitating Hippocampal Synaptic Plasticity in Rats With Chronic Cerebral Hypoperfusion.
The Ghrelin/Growth Hormone Secretagogue Receptor System Is Involved in the Rapid and Sustained Antidepressant-Like Effect of Paeoniflorin.
Isoquercetin Improves Inflammatory Response in Rats Following Ischemic Stroke.
Activation of GPR18 by Resolvin D2 Relieves Pain and Improves Bladder Function in Cyclophosphamide-Induced Cystitis Through Inhibiting TRPV1.
Bardoxolone-Methyl Prevents Oxidative Stress-Mediated Apoptosis and Extracellular Matrix Degradation in vitro and Alleviates Osteoarthritis in vivo.
Puerarin Alleviates UUO-Induced Inflammation and Fibrosis by Regulating the NF-κB P65/STAT3 and TGFβ1/Smads Signaling Pathways.
Pentamidine Inhibits Ovarian Cancer Cell Proliferation and Migration by Maintaining Stability of PTEN in vitro.
The Effects of M1/M2 Macrophages on the mRNA Expression Profile of Diabetic Glomerular Endothelial Cells.
Inhibition of TGF-β2-induced migration and epithelial-mesenchymal transition in ARPE-19 by sulforaphane.
Effect of luteolin on apoptosis and vascular endothelial growth factor in human choroidal melanoma cells.
Maxing Shigan Decoction Mitigates Mycoplasma pneumonia-Induced Pyroptosis in A549 Cells via the NLRP3 Inflammasome.
LncRNA MCTP1-AS1 Regulates EMT Process in Endometrial Cancer by Targeting the miR-650/SMAD7 Axis.
Engeletin Protects Against TNF-α-Induced Apoptosis and Reactive Oxygen Species Generation in Chondrocytes and Alleviates Osteoarthritis in vivo.
Proteomic Profiling of Astrocytic O-GlcNAc Transferase-Related Proteins in the Medial Prefrontal Cortex.
Monomeric CRP Aggravates Myocardial Injury After Myocardial Infarction by Polarizing the Macrophage to Pro-Inflammatory Phenotype Through JNK Signaling Pathway.
Computational Systems Pharmacology, Molecular Docking and Experiments Reveal the Protective Mechanism of Li-Da-Qian Mixture in the Treatment of Glomerulonephritis.
Neutrophil Extracellular Traps Augmented Alveolar Macrophage Pyroptosis via AIM2 Inflammasome Activation in LPS-Induced ALI/ARDS.
A c-Met Inhibitor Suppresses Osteosarcoma Progression via the ERK1/2 Pathway in Human Osteosarcoma Cells.
Fatty Acid-Binding Protein 4 (FABP4) Suppresses Proliferation and Migration of Endometrial Cancer Cells via PI3K/Akt Pathway.
miR-944 Suppresses EGF-Induced EMT in Colorectal Cancer Cells by Directly Targeting GATA6.
Prognostic Implications of the Complement Protein C1Q and Its Correlation with Immune Infiltrates in Osteosarcoma.
An Apoptotic Gene Signature for the Prognosis of Hepatocellular Carcinoma.
Expression and Functional Relevance of ANXA1 in Hypopharyngeal Carcinoma with Lymph Node Metastasis.
Circular RNA ERBB2 Contributes to Proliferation and Migration of Airway Smooth Muscle Cells via miR-98-5p/IGF1R Signaling in Asthma.
FUT7 Promotes the Epithelial-Mesenchymal Transition and Immune Infiltration in Bladder Urothelial Carcinoma.
The cardioprotective effect of the sodium-glucose cotransporter 2 inhibitor dapagliflozin in rats with isoproterenol-induced cardiomyopathy.
Knockdown of VDAC1 alleviates the cognitive dysfunction secondary to sepsis-associated encephalopathy.
Qi Ling decoction reduces gastric cancer cell metastasis by inhibiting MMP-9 through the PI3K/Akt signaling pathway.
Inhibition of mu-opioid receptor suppresses proliferation of hepatocellular carcinoma cells via CD147-p53-MAPK cascade signaling pathway.
Positive Feedback Loop of Long Noncoding RNA OASL-IT1 and Innate Immune Response Restricts the Replication of Zika Virus in Epithelial A549 Cells.
Curcumin promotes the survival of ischemic random skin flaps via autophagy.
TET2 mediated demethylation is involved in the protective effect of triptolide on podocytes.
Comparative analysis identifies significant peptides related to asthma mechanism.
Distinct effects of ANGPT2 on gene expression of glomerular podocytes and mesangial cells.
Sevoflurane prevents pulmonary vascular remodeling and right ventricular dysfunction in pulmonary arterial hypertension in rats.
Dura cells in the etiopathogenesis of Crouzon syndrome: the effects of FGFR2 mutations in the dura cells on the proliferation of osteoblasts through the hippo/YAP mediated transcriptional regulation pathway.
Combination effect of curcumin with docetaxel on the PI3K/AKT/mTOR pathway to induce autophagy and apoptosis in esophageal squamous cell carcinoma.
Downregulation of miRNA-451a Promotes the Differentiation of CD4+ T Cells towards Th2 Cells by Upregulating ETS1 in Childhood Asthma.
PARK2 attenuates house dust mite-induced inflammatory reaction, pyroptosis and barrier dysfunction in BEAS-2B cells by ubiquitinating NLRP3.
The Circadian Gene NPAS2 Act as a Putative Tumor Stimulative Factor for Uterine Corpus Endometrial Carcinoma.
BBOX1-AS1 Accelerates Nasopharyngeal Carcinoma Progression by Sponging miR-3940-3p and Enhancing KPNA2 Upregulation.
LncRNA FOXD3-AS1 Promotes Tumorigenesis of Glioma via Targeting miR-128-3p/SZRD1 Axis.
AGTR1 Inhibits the Progression of Lung Adenocarcinoma.
lncRNA AC007207.2 Promotes Malignant Properties of Osteosarcoma via the miR-1306-5p/SIRT7 Axis.
Stress Granules Modulate SYK to Cause Tau-Associated Neurocognitive Deterioration in 5XFAD Mouse After Anesthesia and Surgery.
Enriched Environment Attenuates Pyroptosis to Improve Functional Recovery After Cerebral Ischemia/Reperfusion Injury.
MALAT-1 is Associated with the Doxorubicin Resistance in U-2OS Osteosarcoma Cells.
Calcitriol Alleviates MPP(+)- and MPTP-Induced Parthanatos Through the VDR/PARP1 Pathway in the Model of Parkinson's Disease.
Intranasal Transplantation of Human Neural Stem Cells Ameliorates Alzheimer's Disease-Like Pathology in a Mouse Model.
Long-Term Administration of Triterpenoids From Ganoderma lucidum Mitigates Age-Associated Brain Physiological Decline via Regulating Sphingolipid Metabolism and Enhancing Autophagy in Mice.
The Non-peptide Angiotensin-(1-7) Mimic AVE 0991 Attenuates Delayed Neurocognitive Recovery After Laparotomy by Reducing Neuroinflammation and Restoring Blood-Brain Barrier Integrity in Aged Rats.
Plakophilin-2 Promotes Lung Adenocarcinoma Development via Enhancing Focal Adhesion and Epithelial-Mesenchymal Transition.
KLF7 Promotes Gastric Carcinogenesis Through Regulation of ANTXR1.
Columbamine-Mediated PTEN/AKT Signal Pathway Regulates the Progression of Glioma.
The Preliminary Study for Postoperative Radiotherapy Survival Associated with RUNX3 and TLR9 Expression in Lung Cancer.
Overexpression of Taspase 1 Predicts Poor Prognosis in Patients with Hepatocellular Carcinoma.
Identification of TRIM56 as a Potential Biomarker for Lung Adenocarcinoma.
Identification and validation of the clinical roles of the VHL-related LncRNAs in clear cell renal cell carcinoma.
SCARA5 inhibits gastric cancer progression via epithelial-mesenchymal transition suppression.
Peri-tumoral brain edema associated with glioblastoma correlates with tumor recurrence.
Long non-coding RNA SNHG25 promotes epithelial ovarian cancer progression by up-regulating COMP.
Elevated expression of Tweety homologue 3 predicts poor clinical outcomes in ovarian cancer.
N6-methyladenosine regulates ATM expression and downstream signaling.
Decreased interferon regulatory factor 6 expression due to DNA hypermethylation predicts an unfavorable prognosis in clear cell renal cell carcinoma.
FGF14-AS2 accelerates tumorigenesis in glioma by forming a feedback loop with miR-320a/E2F1 axis.
RUNX1 regulates the proliferation and chemoresistance of colorectal cancer through the Hedgehog signaling pathway.
Effect of EG00229 on Radiation Resistance of Lung Adenocarcinoma Cells.
miR-552 promotes the proliferation and metastasis of cervical cancer cells through targeting MUC15 pathway.
Lipid Storage and Interferon Response Determine the Phenotype of Ground Glass Hepatocytes in Mice and Humans.
Co-overexpression of RIOK1 and AKT1 as a prognostic risk factor in glioma.
MRPS17 promotes invasion and metastasis through PI3K/AKT signal pathway and could be potential prognostic marker for gastric cancer.
EIF5A expression and its role as a potential diagnostic biomarker in hepatocellular carcinoma.
Demethylzelasteral inhibits proliferation and EMT via repressing Wnt/β-catenin signaling in esophageal squamous cell carcinoma.
Diosgenin From Dioscorea Nipponica Rhizoma Against Graves' Disease-On Network Pharmacology and Experimental Evaluation.
Biphasic Effect of Pirfenidone on Angiogenesis.
PTRF/Cavin-1 as a Novel RNA-Binding Protein Expedites the NF-κB/PD-L1 Axis by Stabilizing lncRNA NEAT1, Contributing to Tumorigenesis and Immune Evasion in Glioblastoma.
Galectin-9/TIM-3 as a Key Regulator of Immune Response in Gliomas With Chromosome 1p/19q Codeletion.
Myricanol Inhibits Platelet Derived Growth Factor-BB-Induced Vascular Smooth Muscle Cells Proliferation and Migration in vitro and Intimal Hyperplasia in vivo by Targeting the Platelet-Derived Growth Factor Receptor-β and NF-κB Signaling.
Hsa-miR-557 Inhibits Osteosarcoma Growth Through Targeting KRAS.
HSP27 Protein Dampens Encephalomyocarditis Virus Replication by Stabilizing Melanoma Differentiation-Associated Gene 5.
Exercise Capacity Is Improved by Levosimendan in Heart Failure and Sarcopenia via Alleviation of Apoptosis of Skeletal Muscle.
Altered Expression of Par3, aPKC-λ, and Lgl1 in Hippocampus in Kainic Acid-Induced Status Epilepticus Rat Model.
FBXO22 Promotes Growth and Metastasis and Inhibits Autophagy in Epithelial Ovarian Cancers via the MAPK/ERK Pathway.
Cardiac Effects of Treadmill Running at Different Intensities in a Rat Model.
Autophagy Induced by Micheliolide Alleviates Acute Irradiation-Induced Intestinal Injury via Inhibition of the NLRP3 Inflammasome.
BCI Suppresses RANKL-Mediated Osteoclastogenesis and Alleviates Ovariectomy-Induced Bone Loss.
Histone H2A Nuclear/Cytoplasmic Trafficking Is Essential for Negative Regulation of Antiviral Immune Response and Lysosomal Degradation of TBK1 and IRF3.
SOAT1 Promotes Gastric Cancer Lymph Node Metastasis Through Lipid Synthesis.
PARP Inhibitor Upregulates PD-L1 Expression and Provides a New Combination Therapy in Pancreatic Cancer.
Physalin A Inhibits MAPK and NF-κB Signal Transduction Through Integrin αVβ3 and Exerts Chondroprotective Effect.
Activation of 1-Aminocyclopropane-1-Carboxylic Acid Synthases Sets Stomatal Density and Clustered Ratio on Leaf Epidermis of Arabidopsis in Response to Drought.
Characterization of Pathogenesis and Inflammatory Responses to Experimental Parechovirus Encephalitis.
Duhaldea pterocaula (Franch.) Anderb. Attenuates Nociception and Inflammation via GABA(A) Receptors.
Nox4 Promotes RANKL-Induced Autophagy and Osteoclastogenesis via Activating ROS/PERK/eIF-2α/ATF4 Pathway.
Chinese Herbal Preparation SaiLuoTong Alleviates Brain Ischemia via Nrf2 Antioxidation Pathway-Dependent Cerebral Microvascular Protection.
An Integrative Pharmacology Based Analysis of Refined Liuweiwuling Against Liver Injury: A Novel Component Combination and Hepaprotective Mechanism.
Naringenin Regulates FKBP4/NR3C1/NRF2 Axis in Autophagy and Proliferation of Breast Cancer and Differentiation and Maturation of Dendritic Cell.
Micronized Palmitoylethanolamide Ameliorates Methionine- and Choline-Deficient Diet-Induced Nonalcoholic Steatohepatitis via Inhibiting Inflammation and Restoring Autophagy.
Disease-Modifying Anti-rheumatic Drug Prescription Baihu-Guizhi Decoction Attenuates Rheumatoid Arthritis via Suppressing Toll-Like Receptor 4-mediated NLRP3 Inflammasome Activation.
Remimazolam Protects Against LPS-Induced Endotoxicity Improving Survival of Endotoxemia Mice.
Clostridium butyricum Supplement Can Ameliorate the Intestinal Barrier Roles in Broiler Chickens Experimentally Infected With Clostridium perfringens.
Screening of a Small Molecule Compound Library Identifies Toosendanin as an Inhibitor Against Bunyavirus and SARS-CoV-2.
Activation of Yes-Associated Protein/PDZ-Binding Motif Pathway Contributes to Endothelial Dysfunction and Vascular Inflammation in AngiotensinII Hypertension.
Selective STAT3 Inhibitor Alantolactone Ameliorates Osteoarthritis via Regulating Chondrocyte Autophagy and Cartilage Homeostasis.
Fascin-1 is Highly Expressed Specifically in Microglia After Spinal Cord Injury and Regulates Microglial Migration.
VDR Signaling via the Enzyme NAT2 Inhibits Colorectal Cancer Progression.
Samotolisib Attenuates Acute Liver Injury Through Inhibiting Caspase-11-Mediated Pyroptosis Via Regulating E3 Ubiquitin Ligase Nedd4.
Huangqi Shengmai Yin Ameliorates Myocardial Fibrosis by Activating Sirtuin3 and Inhibiting TGF-β/Smad Pathway.
Extracellular CIRP Induces an Inflammatory Phenotype in Pulmonary Fibroblasts via TLR4.
ZnT8 Deficiency Protects From APAP-Induced Acute Liver Injury by Reducing Oxidative Stress Through Upregulating Hepatic Zinc and Metallothioneins.
Identification of a Novel Epigenetic Signature CHFR as a Potential Prognostic Gene Involved in Metastatic Clear Cell Renal Cell Carcinoma.
EGFR-IL-6 Signaling Axis Mediated the Inhibitory Effect of Methylseleninic Acid on Esophageal Squamous Cell Carcinoma.
Combined Administration of Vitamin D(3) and Geniposide Is Less Effective than Single Use of Vitamin D(3) or Geniposide in the Treatment of Ulcerative Colitis.
Mefunidone Ameliorates Bleomycin-Induced Pulmonary Fibrosis in Mice.
Sinensetin Reduces Osteoarthritis Pathology in the Tert-Butyl Hydroperoxide-Treated Chondrocytes and the Destabilization of the Medial Meniscus Model Mice via the AMPK/mTOR Signaling Pathway.
Azithromycin Attenuates Bleomycin-Induced Pulmonary Fibrosis Partly by Inhibiting the Expression of LOX and LOXL-2.
Novel Molecule Nell-1 Promotes the Angiogenic Differentiation of Dental Pulp Stem Cells.
Preexposure and Postexposure Prophylaxis of Rabies With Adeno-Associated Virus Expressing Virus-Neutralizing Antibody in Rodent Models.
RPL22 Overexpression Promotes Psoriasis-Like Lesion by Inducing Keratinocytes Abnormal Biological Behavior.
Screening and Identification of Key Genes for Activation of Islet Stellate Cell.
Characterization of the Potential Role of NTPCR in Epithelial Ovarian Cancer by Integrating Transcriptomic and Metabolomic Analysis.
Preclinical Investigation of Alpinetin in the Treatment of Cancer-Induced Cachexia via Activating PPARγ.
Overexpression of SHMT2 Predicts a Poor Prognosis and Promotes Tumor Cell Growth in Bladder Cancer.
Loganin Inhibits Angiotensin II-Induced Cardiac Hypertrophy Through the JAK2/STAT3 and NF-κB Signaling Pathways.
Traditional Chinese Medication Tongxinluo Attenuates Lipidosis in Ox-LDL-Stimulated Macrophages by Enhancing Beclin-1-Induced Autophagy.
SEC23A Is an Independent Prognostic Biomarker in Bladder Cancer Correlated With MAPK Signaling.
Pig Liver Esterases Hydrolyze Endocannabinoids and Promote Inflammatory Response.
Feasibility and Mechanism Analysis of Shenfu Injection in the Treatment of Idiopathic Pulmonary Fibrosis.
M2a Macrophage-Secreted CHI3L1 Promotes Extracellular Matrix Metabolic Imbalances via Activation of IL-13Rα2/MAPK Pathway in Rat Intervertebral Disc Degeneration.
Atractylodin Attenuates Dextran Sulfate Sodium-Induced Colitis by Alleviating Gut Microbiota Dysbiosis and Inhibiting Inflammatory Response Through the MAPK Pathway.
A Novel Loss-of-Function MKRN3 Variant in a Chinese Patient With Familial Precocious Puberty: A Case Report and Functional Study.
STAT3-Dependent Gene TRIM5γ Interacts With HBx Through a Zinc Binding Site on the BBox Domain.
Lipidomics Revealed Alteration of Sphingolipid Metabolism During the Reparative Phase After Myocardial Infarction Injury.
SARS-CoV-2 Membrane Protein Inhibits Type I Interferon Production Through Ubiquitin-Mediated Degradation of TBK1.
Targeting Glycogen Synthase Kinase 3 Beta Regulates CD47 Expression After Myocardial Infarction in Rats via the NF-κB Signaling Pathway.
Characterization of Two Loss-of-Function NF1 Variants in Chinese Patients and Potential Molecular Interpretations of Phenotypes.
DsbA-L Ameliorates Renal Injury Through the AMPK/NLRP3 Inflammasome Signaling Pathway in Diabetic Nephropathy.
The New PI3K/mTOR Inhibitor GNE-477 Inhibits the Malignant Behavior of Human Glioblastoma Cells.
Effect of Protein O-Mannosyltransferase (MSMEG_5447) on M. smegmatis and Its Survival in Macrophages.
Pulmonary Artery Smooth Muscle Cell Senescence Promotes the Proliferation of PASMCs by Paracrine IL-6 in Hypoxia-Induced Pulmonary Hypertension.
SARS-CoV-2 Accessory Protein ORF7b Mediates Tumor Necrosis Factor-α-Induced Apoptosis in Cells.
Interferon-Lambda 1 Inhibits Staphylococcus aureus Colonization in Human Primary Keratinocytes.
The Treatment of Rhodiola Mimics Exercise to Resist High-Fat Diet-Induced Muscle Dysfunction via Sirtuin1-Dependent Mechanisms.
Anti-Hyperuricemic and Nephroprotective Effects of Dihydroberberine in Potassium Oxonate- and Hypoxanthine-Induced Hyperuricemic Mice.
Bellidifolin Ameliorates Isoprenaline-Induced Myocardial Fibrosis by Regulating TGF-β1/Smads and p38 Signaling and Preventing NR4A1 Cytoplasmic Localization.
Berberine Attenuates Chronic Atrophic Gastritis Induced by MNNG and Its Potential Mechanism.
Effects of Allicin on Late Sodium Current Caused by ΔKPQ-SCN5A Mutation in HEK293 Cells.
The Crucial Role of PPARγ-Egr-1-Pro-Inflammatory Mediators Axis in IgG Immune Complex-Induced Acute Lung Injury.
Repurposing of Pirfenidone (Anti-Pulmonary Fibrosis Drug) for Treatment of Rheumatoid Arthritis.
Jian-Pi-Yi-Shen Formula Ameliorates Oxidative Stress, Inflammation, and Apoptosis by Activating the Nrf2 Signaling in 5/6 Nephrectomized Rats.
Sinomenine Attenuated Capsaicin-Induced Increase in Cough Sensitivity in Guinea Pigs by Inhibiting SOX5/TRPV1 Axis and Inflammatory Response.
Remdesivir Inhibits Tubulointerstitial Fibrosis in Obstructed Kidneys.
Compound Dihuang Granule Inhibits Nigrostriatal Pathway Apoptosis in Parkinson's Disease by Suppressing the JNK/AP-1 Pathway.
MicroRNA-497 Reduction and Increase of Its Family Member MicroRNA-424 Lead to Dysregulation of Multiple Inflammation Related Genes in Synovial Fibroblasts With Rheumatoid Arthritis.
Hepatitis B Surface Antigen Suppresses the Activation of Nuclear Factor Kappa B Pathway via Interaction With the TAK1-TAB2 Complex.
Quercitrin Attenuates Acetaminophen-Induced Acute Liver Injury by Maintaining Mitochondrial Complex I Activity.
PRMT5 functionally associates with EZH2 to promote colorectal cancer progression through epigenetically repressing CDKN2B expression.
Inhibition of BAG3 enhances the anticancer effect of shikonin in hepatocellular carcinoma.
Honokiol induces ferroptosis in colon cancer cells by regulating GPX4 activity.
NONO phase separation enhances DNA damage repair by accelerating nuclear EGFR-induced DNA-PK activation.
Platelet-derived microvesicles induce calcium oscillations and promote VSMC migration via TRPV4.
Glycosylation of Siglec15 promotes immunoescape and tumor growth.
YY1-mediated reticulocalbin-2 upregulation promotes the hepatocellular carcinoma progression via activating MYC signaling.
TSL-1502, a glucuronide prodrug of a poly (ADP-ribose) polymerase (PARP) inhibitor, exhibits potent anti-tumor activity in preclinical models.
TM2D1 contributes the epithelial-mesenchymal transition of hepatocellular carcinoma via modulating AKT/β-catenin axis.
A Mitochondrial DNA Variant Elevates the Risk of Gallstone Disease by Altering Mitochondrial Function.
Loss of BRMS2 induces cell growth inhibition and translation capacity reduction in colorectal cancer cells.
S100A11 Promotes Liver Steatosis via FOXO1-Mediated Autophagy and Lipogenesis.
Exosome-mediated delivery of inflammation-responsive Il-10 mRNA for controlled atherosclerosis treatment.
Rapid design and development of CRISPR-Cas13a targeting SARS-CoV-2 spike protein.
Designer exosomes for targeted and efficient ferroptosis induction in cancer via chemo-photodynamic therapy.
TRPV2-spike protein interaction mediates the entry of SARS-CoV-2 into macrophages in febrile conditions.
Nanoparticle encapsulation of non-genotoxic p53 activator Inauhzin-C for improved therapeutic efficacy.
A nano-predator of pathological MDMX construct by clearable supramolecular gold(I)-thiol-peptide complexes achieves safe and potent anti-tumor activity.
KAT6A, a novel regulator of β-catenin, promotes tumorigenicity and chemoresistance in ovarian cancer by acetylating COP1.
Relieving lipid accumulation through UCP1 suppresses the progression of acute kidney injury by promoting the AMPK/ULK1/autophagy pathway.
Cardiac telocytes inhibit cardiac microvascular endothelial cell apoptosis through exosomal miRNA-21-5p-targeted cdip1 silencing to improve angiogenesis following myocardial infarction.
KB-68A7.1 Inhibits Hepatocellular Carcinoma Development Through Binding to NSD1 and Suppressing Wnt/β-Catenin Signalling.
CDKN2A Deletion Leading to Hematogenous Metastasis of Human Gastric Carcinoma.
MAPK Activated Protein Kinase 3 Is a Prognostic-Related Biomarker and Associated With Immune Infiltrates in Glioma.
SARS-CoV-2 Spike Antagonizes Innate Antiviral Immunity by Targeting Interferon Regulatory Factor 3.
The Circ_0001367/miR-545-3p/LUZP1 Axis Regulates Cell Proliferation, Migration and Invasion in Glioma Cells.
Downregulation of SLC27A6 by DNA Hypermethylation Promotes Proliferation but Suppresses Metastasis of Nasopharyngeal Carcinoma Through Modulating Lipid Metabolism.
Preclinical Evaluation of the HDAC Inhibitor Chidamide in Transformed Follicular Lymphoma.
Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Membrane (M) and Spike (S) Proteins Antagonize Host Type I Interferon Response.
GPI Is a Prognostic Biomarker and Correlates With Immune Infiltrates in Lung Adenocarcinoma.
A Class of Protein-Coding RNAs Binds to Polycomb Repressive Complex 2 and Alters Histone Methylation.
Combination of Auranofin and ICG-001 Suppress the Proliferation and Metastasis of Colon Cancer.
Pseudomonas aeruginosa PcrV Enhances the Nitric Oxide-Mediated Tumoricidal Activity of Tumor-Associated Macrophages via a TLR4/PI3K/AKT/mTOR-Glycolysis-Nitric Oxide Circuit.
DEAD-Box Helicase DDX6 Facilitated RIG-I-Mediated Type-I Interferon Response to EV71 Infection.
TFCP2 Overcomes Senescence by Cooperating With SREBP2 to Activate Cholesterol Synthesis in Pancreatic Cancer.
LncRNA LGALS8-AS1 Promotes Breast Cancer Metastasis Through miR-125b-5p/SOX12 Feedback Regulatory Network.
Siglec-15 Promotes Tumor Progression in Osteosarcoma via DUSP1/MAPK Pathway.
METTL3 Promotes the Resistance of Glioma to Temozolomide via Increasing MGMT and ANPG in a m(6)A Dependent Manner.
SPNS2 Downregulation Induces EMT and Promotes Colorectal Cancer Metastasis via Activating AKT Signaling Pathway.
TIPE2 Suppresses Malignancy of Pancreatic Cancer Through Inhibiting TGFβ1 Mediated Signaling Pathway.
Downregulation of miR-135b-5p Suppresses Progression of Esophageal Cancer and Contributes to the Effect of Cisplatin.
miR-1258 Attenuates Tumorigenesis Through Targeting E2F1 to Inhibit PCNA and MMP2 Transcription in Glioblastoma.
The Deubiquitinase USP39 Promotes ESCC Tumorigenesis Through Pre-mRNA Splicing of the mTORC2 Component Rictor.
Pinocembrin Inhibits the Proliferation and Metastasis of Breast Cancer via Suppression of the PI3K/AKT Signaling Pathway.
N2E4, a Monoclonal Antibody Targeting Neuropilin-2, Inhibits Tumor Growth and Metastasis in Pancreatic Ductal Adenocarcinoma via Suppressing FAK/Erk/HIF-1α Signaling.
A Novel Mechanism of the c-Myc/NEAT1 Axis Mediating Colorectal Cancer Cell Response to Photodynamic Therapy Treatment.
Analysis of Long Noncoding RNAs in Aila-Induced Non-Small Cell Lung Cancer Inhibition.
MiR-489-3p Reduced Pancreatic Cancer Proliferation and Metastasis By Targeting PKM2 and LDHA Involving Glycolysis.
SLC1A4: A Powerful Prognostic Marker and Promising Therapeutic Target for HCC.
LncRNA SNHG8 Promotes Proliferation and Inhibits Apoptosis of Diffuse Large B-Cell Lymphoma via Sponging miR-335-5p.
Long Noncoding RNA SNHG12 Promotes Gastric Cancer Proliferation by Binding to HuR and Stabilizing YWHAZ Expression Through the AKT/GSK-3β Pathway.
The Overexpression of Acyl-CoA Medium-Chain Synthetase-3 (ACSM3) Suppresses the Ovarian Cancer Progression via the Inhibition of Integrin β1/AKT Signaling Pathway.
TFEB Promotes Prostate Cancer Progression via Regulating ABCA2-Dependent Lysosomal Biogenesis.
DDX19A Promotes Metastasis of Cervical Squamous Cell Carcinoma by Inducing NOX1-Mediated ROS Production.
circATP2B1 Promotes Aerobic Glycolysis in Gastric Cancer Cells Through Regulation of the miR-326 Gene Cluster.
Overexpressed Tumor Suppressor Exosomal miR-15a-5p in Cancer Cells Inhibits PD1 Expression in CD8+T Cells and Suppresses the Hepatocellular Carcinoma Progression.
Identification and Confirmation of the miR-30 Family as a Potential Central Player in Tobacco-Related Head and Neck Squamous Cell Carcinoma.
miR-4461 Regulates the Proliferation and Metastasis of Ovarian Cancer Cells and Cisplatin Resistance.
miR-139-5p Loss-Mediated WTAP Activation Contributes to Hepatocellular Carcinoma Progression by Promoting the Epithelial to Mesenchymal Transition.
PSMC2 Regulates Cell Cycle Progression Through the p21/Cyclin D1 Pathway and Predicts a Poor Prognosis in Human Hepatocellular Carcinoma.
The Role of Tim-3 on dNK Cells Dysfunction During Abnormal Pregnancy With Toxoplasma gondii Infection.
Bispecific c-Met/PD-L1 CAR-T Cells Have Enhanced Therapeutic Effects on Hepatocellular Carcinoma.
Schisandrin Restores the Amyloid β-Induced Impairments on Mitochondrial Function, Energy Metabolism, Biogenesis, and Dynamics in Rat Primary Hippocampal Neurons.
Preliminary therapeutic and mechanistic evaluation of S-allylmercapto-N-acetylcysteine in the treatment of pulmonary emphysema.
Protective effect and mechanism of nicotinamide adenine dinucleotide against optic neuritis in mice with experimental autoimmune encephalomyelitis.
ITPRIP promotes glioma progression by linking MYL9 to DAPK1 inhibition.
CPEB1 enhances erastin-induced ferroptosis in gastric cancer cells by suppressing twist1 expression.
ZMPSTE24 Regulates SARS-CoV-2 Spike Protein-enhanced Expression of Endothelial PAI-1.
MiR-499a prevents astrocytes mediated inflammation in ischemic stroke by targeting PTEN.
Riluzole does not ameliorate disease caused by cytoplasmic TDP-43 in a mouse model of amyotrophic lateral sclerosis.
TAZ as a novel regulator of oxidative damage in decidualization via Nrf2/ARE/Foxo1 pathway.
M2-polarized macrophages mediate wound healing by regulating connective tissue growth factor via AKT, ERK1/2, and STAT3 signaling pathways.
Activation of Transient Receptor Potential Ankyrin 1 and Vanilloid 1 Channels Promotes Odontogenic Differentiation of Human Dental Pulp Cells.
Identifying miRNA modules associated with progression of keloids through weighted gene co-expression network analysis and experimental validation in vitro.
miR-138 inhibits epithelial-mesenchymal transition in silica-induced pulmonary fibrosis by regulating ZEB2.
miRNA‑7515 suppresses pancreatic cancer cell proliferation, migration and invasion via downregulating IGF‑1 expression.
Chronic stress promotes glioma cell proliferation via the PI3K/Akt signaling pathway.
MicroRNA-214 contributes to Ang II-induced cardiac hypertrophy by targeting SIRT3 to provoke mitochondrial malfunction.
Genetically encoded FRET fluorescent sensor designed for detecting MOF histone acetyltransferase activity in vitro and in living cells.
In Vivo Characterization of Endogenous Cardiovascular Extracellular Vesicles in Larval and Adult Zebrafish.
The scaffold protein IQGAP1 links heat-induced stress signals to alternative splicing regulation in gastric cancer cells.
miR-351-3p promotes rat amniotic fluid-derived mesenchymal stromal cell proliferation via targeting the coding sequence of Abca4.
FSH modulated cartilage ECM metabolism by targeting the PKA/CREB/SOX9 pathway.
miRNA-10a-5p inhibits cell metastasis in hepatocellular carcinoma via targeting SKA1.
Triclosan regulates the Nrf2/HO-1 pathway through the PI3K/Akt/JNK signaling cascade to induce oxidative damage in neurons.
TRIP13 exerts a cancer-promoting role in cervical cancer by enhancing Wnt/β-catenin signaling via ACTN4.
Hsp70 chaperones TDP-43 in dynamic, liquid-like phase and prevents it from amyloid aggregation.
The deubiquitinase USP10 restores PTEN activity and inhibits non-small cell lung cancer cell proliferation.
AMPK phosphorylates PPARδ to mediate its stabilization, inhibit glucose and glutamine uptake and colon tumor growth.
The inhibitory effect of the deubiquitinase cylindromatosis (CYLD) on inflammatory responses in human gingival fibroblasts.
Human forebrain endothelial cell therapy for psychiatric disorders.
N-3 polyunsaturated fatty acids promote astrocyte differentiation and neurotrophin production independent of cAMP in patient-derived neural stem cells.
DNM3OS regulates GAPDH expression and influences the molecular pathogenesis of Huntington's disease.
The effects of NCBP3 on METTL3-mediated m6A RNA methylation to enhance translation process in hypoxic cardiomyocytes.
Effects of different intensities of continuous training on vascular inflammation and oxidative stress in spontaneously hypertensive rats.
Abdominal paracentesis drainage attenuates intestinal mucosal barrier damage through macrophage polarization in severe acute pancreatitis.
miR‑140‑5p alleviates mouse liver ischemia/reperfusion injury by targeting CAPN1.
Endoglin deficiency impairs VEGFR2 but not FGFR1 or TIE2 activation and alters VEGF-mediated cellular responses in human primary endothelial cells.
PDIA6 promotes pancreatic cancer progression and immune escape through CSN5-mediated deubiquitination of β-catenin and PD-L1.
PARP inhibitor niraparib as a radiosensitizer promotes antitumor immunity of radiotherapy in EGFR-mutated non-small cell lung cancer.
Human Bone Mesenchymal Stem Cell-Derived Exosomes Inhibit IL-1β-Induced Inflammation in Osteoarthritis Chondrocytes.
OGT regulated O-GlcNacylation promotes migration and invasion by activating IL-6/STAT3 signaling in NSCLC cells.
PPP1CA/YAP/GS/Gln/mTORC1 pathway activates retinal Müller cells during diabetic retinopathy.
Interleukin-4 protects mice against lethal influenza and Streptococcus pneumoniae co-infected pneumonia.
MeCP2 prevents age-associated cognitive decline via restoring synaptic plasticity in a senescence-accelerated mouse model.
P76RBE silencing inhibits ovarian cancer cell proliferation, migration, and invasion via suppressing the integrin β1/NF-κB pathway.
Photoresponsive PAMAM-Assembled Nanocarrier Loaded with Autophagy Inhibitor for Synergistic Cancer Therapy.
The miR-28-5p-CAMTA2 axis regulates colon cancer progression via Wnt/β-catenin signaling.
CENPA is one of the potential key genes associated with the proliferation and prognosis of ovarian cancer based on integrated bioinformatics analysis and regulated by MYBL2.
Orf Virus ORF120 Protein Positively Regulates the NF-κB Pathway by Interacting with G3BP1.
NSUN2 modified by SUMO-2/3 promotes gastric cancer progression and regulates mRNA m5C methylation.
HSP90 acts as a senomorphic target in senescent retinal pigmental epithelial cells.
Microglia modulation with 1070-nm light attenuates Aβ burden and cognitive impairment in Alzheimer's disease mouse model.
Cilium induction triggers differentiation of glioma stem cells.
m(6)A demethylase ALKBH5 suppression contributes to esophageal squamous cell carcinoma progression.
The genomic architecture of EBV and infected gastric tissue from precursor lesions to carcinoma.
A ciliopathy complex builds distal appendages to initiate ciliogenesis.
TDP-43 mediates SREBF2-regulated gene expression required for oligodendrocyte myelination.
Live Combined B. subtilis and E. faecium Alleviate Liver Inflammation, Improve Intestinal Barrier Function, and Modulate Gut Microbiota in Mice with Non-Alcoholic Fatty Liver Disease.
Curcumol inhibits encephalomyocarditis virus by promoting IFN-β secretion.
Stimulation of ROS Generation by Extract of Warburgia ugandensis Leading to G(0)/G(1) Cell Cycle Arrest and Antiproliferation in A549 Cells.
HIF-1α/JMJD1A signaling regulates inflammation and oxidative stress following hyperglycemia and hypoxia-induced vascular cell injury.
Proximity Labeling, Quantitative Proteomics, and Biochemical Studies Revealed the Molecular Mechanism for the Inhibitory Effect of Indisulam on the Proliferation of Gastric Cancer Cells.
Inhibition of DNMT-1 alleviates ferroptosis through NCOA4 mediated ferritinophagy during diabetes myocardial ischemia/reperfusion injury.
A Versatile Nanoplatform for Broad-Spectrum Immunotherapy by Reversing the Tumor Microenvironment.
Therapeutic Interaction of Apatinib and Chidamide in T-Cell Acute Lymphoblastic Leukemia through Interference with Mitochondria Associated Biogenesis and Intrinsic Apoptosis.
A Novel Calpain Inhibitor Compound Has Protective Effects on a Zebrafish Model of Spinocerebellar Ataxia Type 3.
Exosomal microRNA-588 from M2 polarized macrophages contributes to cisplatin resistance of gastric cancer cells.
Engineering Extracellular Vesicles Restore the Impaired Cellular Uptake and Attenuate Intervertebral Disc Degeneration.
Dual Inhibition of Endoplasmic Reticulum Stress and Oxidation Stress Manipulates the Polarization of Macrophages under Hypoxia to Sensitize Immunotherapy.
Changes in energy metabolism and respiration in different tracheal narrowing in rats.
Macrophage-mediated multi-mode drug release system for photothermal combined with anti-inflammatory therapy against postoperative recurrence of triple negative breast cancer.
A novel pyrrole-imidazole polyamide targets Aurora kinase A and suppresses tumor growth in vivo.
Metabolic nuclear receptors coordinate energy metabolism to regulate Sox9(+) hepatocyte fate.
Costunolide Loaded in pH-Responsive Mesoporous Silica Nanoparticles for Increased Stability and an Enhanced Anti-Fibrotic Effect.
Nuclear speckle specific hnRNP D-like prevents age- and AD-related cognitive decline by modulating RNA splicing.
Xenon Nanobubbles for the Image-Guided Preemptive Treatment of Acute Ischemic Stroke via Neuroprotection and Microcirculatory Restoration.
CD36 and DGAT2 facilitate the lipid-lowering effect of chitooligosaccharides via fatty acid intake and triglyceride synthesis signaling.
Isonicotinylation is a histone mark induced by the anti-tuberculosis first-line drug isoniazid.
Deletion of phosphatidylserine flippase β-subunit Tmem30a in satellite cells leads to delayed skeletal muscle regeneration.
RIOK2 Inhibitor NSC139021 Exerts Anti-Tumor Effects on Glioblastoma via Inducing Skp2-Mediated Cell Cycle Arrest and Apoptosis.
Lactobacillus johnsonii L531 Alleviates the Damage Caused by Salmonella Typhimurium via Inhibiting TLR4, NF-κB, and NLRP3 Inflammasome Signaling Pathways.
MYO10 drives genomic instability and inflammation in cancer.
Isopsoralen ameliorates rheumatoid arthritis by targeting MIF.
MicroRNA-550a-3-5p controls the brain metastasis of lung cancer by directly targeting YAP1.
EETs/sEHi alleviates nociception by blocking the crosslink between endoplasmic reticulum stress and neuroinflammation in a central poststroke pain model.
PRMT5 regulates cell pyroptosis by silencing CASP1 in multiple myeloma.
Latcripin-7A from Lentinula edodes C(91-3) induces apoptosis, autophagy, and cell cycle arrest at G1 phase in human gastric cancer cells via inhibiting PI3K/Akt/mTOR signaling.
Round Scad-Derived Octapeptide WCPFSRSF Confers Neuroprotection by Regulating Akt/Nrf2/NFκB Signaling.
The protection of selenium against cadmium-induced mitophagy via modulating nuclear xenobiotic receptors response and oxidative stress in the liver of rabbits.
Co-exposure to BPA and DEHP enhances susceptibility of mammary tumors via up-regulating Esr1/HDAC6 pathway in female rats.
PM2.5-induced lung injury is attenuated in macrophage-specific NLRP3 deficient mice.
Physiologically detectable bisphenol A impairs human sperm functions by reducing protein-tyrosine phosphorylation.
Sigma-1 receptor regulates mitophagy in dopaminergic neurons and contributes to dopaminergic protection.
Scoparone inhibits pancreatic cancer through PI3K/Akt signaling pathway.
Quercitrin Rapidly Alleviated Depression-like Behaviors in Lipopolysaccharide-Treated Mice: The Involvement of PI3K/AKT/NF-κB Signaling Suppression and CREB/BDNF Signaling Restoration in the Hippocampus.
Circular RNA ZNF609 enhances proliferation and glycolysis during glioma progression by miR-378b/SLC2A1 axis.
Protective Effects and Mechanisms of Procyanidins on Parkinson's Disease In Vivo and In Vitro.
Genome-wide mRNA profiling identifies the NRF2-regulated lymphocyte oxidative stress status in patients with silicosis.
TNFSF9 promotes metastasis of pancreatic cancer through Wnt/Snail signaling and M2 polarization of macrophages.
LPCAT1 reprogramming cholesterol metabolism promotes the progression of esophageal squamous cell carcinoma.
Hypoxia regulates overall mRNA homeostasis by inducing Met(1)-linked linear ubiquitination of AGO2 in cancer cells.
Ketamine ameliorates depressive-like behaviors in mice through increasing glucose uptake regulated by the ERK/GLUT3 signaling pathway.
2,5-dimethyl celecoxib induces apoptosis and autophagy via activation of ROS/JNK axis in nasopharyngeal carcinoma cells.
A dual-role of SARS-CoV-2 nucleocapsid protein in regulating innate immune response.
MIER3 induces epithelial-mesenchymal transition and promotes breast cancer cell aggressiveness via forming a co-repressor complex with HDAC1/HDAC2/Snail.
Differential expression of microRNAs in human endometrium after implantation of an intrauterine contraceptive device containing copper.
Formosanin C attenuates lipopolysaccharide-induced inflammation through nuclear factor-κB inhibition in macrophages.
A general role for TANGO1, encoded by MIA3, in secretory pathway organization and function.
CLEC5A knockdown protects against cardiac dysfunction after myocardial infarction by suppressing macrophage polarization, NLRP3 inflammasome activation, and pyroptosis.
Inhibition of YAP activation attenuates renal injury and fibrosis in angiotensin II hypertensive mice.
Iguratimod decreases bleomycin-induced pulmonary fibrosis in association with inhibition of TNF-α in mice.
A botanical dietary supplement from white peony and licorice attenuates nonalcoholic fatty liver disease by modulating gut microbiota and reducing inflammation.
USP41 promotes breast cancer via regulating RACK1.
MYO1B enhances colorectal cancer metastasis by promoting the F-actin rearrangement and focal adhesion assembly via RhoA/ROCK/FAK signaling.
MET overexpression contributes to STAT4-PD-L1 signaling activation associated with tumor-associated, macrophages-mediated immunosuppression in primary glioblastomas.
Concentrated growth factor regulates the macrophage-mediated immune response.
YAP drives fate conversion and chemoresistance of small cell lung cancer.
Immutol regulates CD4(+)Tregs, CD8(+)Tregs and pDCs via IDO signaling pathway to induce immune tolerance in rat heart allograft transplant.
Distinct pathogenic mechanisms of various RARS1 mutations in Pelizaeus-Merzbacher-like disease.
Establishment of a second generation homozygous CRISPRa human induced pluripotent stem cell (hiPSC) line for enhanced levels of endogenous gene activation.
Serine/threonine kinase 17b (STK17B) signalling regulates Purkinje cell dendritic development and is altered in multiple spinocerebellar ataxias.
ErbB4 mediates amyloid β-induced neurotoxicity through JNK/tau pathway activation: Implications for Alzheimer's disease.
Functional expression of TRPA1 channel, TRPV1 channel and TMEM100 in human odontoblasts.
GFI1 promotes the proliferation and migration of esophageal squamous cell carcinoma cells through the inhibition of SOCS1 expression.
Lactate and glutamine support NADPH generation in cancer cells under glucose deprived conditions.
Mono-macrophage-Derived MANF Alleviates Bacterial Myocarditis by Inhibiting NF-kappaB Activation and Myocardial Inflammation.
Cystatin F acts as a mediator of immune suppression in glioblastoma.
Gossypol, a novel modulator of VCP, induces autophagic degradation of mutant huntingtin by promoting the formation of VCP/p97-LC3-mHTT complex.
Nicotinamide phosphoribosyltransferase inhibitor ameliorates mouse aging-induced cognitive impairment.
High-content screening of diterpenoids from Isodon species as autophagy modulators and the functional study of their antiviral activities.
Role of Intracellular Distribution of Feline and Bovine SAMHD1 Proteins in Lentiviral Restriction.
SETD8 involved in the progression of inflammatory bowel disease via epigenetically regulating p62 expression.
Therapeutic potential of isobavachalcone, a natural flavonoid, in murine experimental colitis by inhibiting NF-κB p65.
Pericytes augment glioblastoma cell resistance to temozolomide through CCL5-CCR5 paracrine signaling.
Bakuchiol ameliorates cerebral ischemia-reperfusion injury by modulating NLRP3 inflammasome and Nrf2 signaling.
Vitamin D decreases Porphyromonas gingivalis internalized into macrophages by promoting autophagy.
High-Throughput Screening to Identify Small Molecules That Selectively Inhibit APOL1 Protein Level in Podocytes.
Oridonin prevents oxidative stress-induced endothelial injury via promoting Nrf-2 pathway in ischaemic stroke.
Hydrogen sulphide reduced the accumulation of lipid droplets in cardiac tissues of db/db mice via Hrd1 S-sulfhydration.
SPOP promotes CDCA5 degradation to regulate prostate cancer progression via the AKT pathway.
Knockdown of ALDH1A3 reduces breast cancer stem cell marker CD44 via the miR-7-TGFBR2-Smad3-CD44 regulatory axis.
Establishment of incontinence-associated dermatitis rat models and assessment of the therapeutic effects of zinc oxide, painless skin protective film and silicone dressing.
The adjuvanticity of manganese for microbial vaccines via activating the IRF5 signaling pathway.
PPARα agonist WY-14,643 induces adipose atrophy and fails to blunt chronic ethanol-induced hepatic fat accumulation in mice lacking adipose FGFR1.
Nestin Is Required for Spindle Assembly and Cell-Cycle Progression in Glioblastoma Cells.
Membrane-Associated RING-CH 8 Functions as a Novel PD-L1 E3 Ligase to Mediate PD-L1 Degradation Induced by EGFR Inhibitors.
4,4'-Dimethoxychalcone regulates redox homeostasis by targeting riboflavin metabolism in Parkinson's disease therapy.
TSPAN1 promotes autophagy flux and mediates cooperation between WNT-CTNNB1 signaling and autophagy via the MIR454-FAM83A-TSPAN1 axis in pancreatic cancer.
Intrinsic bioactivity of black phosphorus nanomaterials on mitotic centrosome destabilization through suppression of PLK1 kinase.
Inhibition of sEH via stabilizing the level of EETs alleviated Alzheimer's disease through GSK3β signaling pathway.
Salidroside alleviates taurolithocholic acid 3-sulfate-induced AR42J cell injury.
Inhibition of autophagy with Chloroquine enhanced apoptosis induced by 5-aminolevulinic acid-photodynamic therapy in secondary hyperparathyroidism primary cells and organoids.
Synergic radiosensitization of sinomenine hydrochloride and radioiodine on human papillary thyroid carcinoma cells.
ATG16L2 overexpression is associated with a good prognosis in colorectal cancer.
KIF2C: a novel link between Wnt/β-catenin and mTORC1 signaling in the pathogenesis of hepatocellular carcinoma.
Travelling ultrasound promotes vasculogenesis of three-dimensional-monocultured human umbilical vein endothelial cells.
Transcription factor POU4F2 promotes colorectal cancer cell migration and invasion through hedgehog-mediated epithelial-mesenchymal transition.
PD0325901, an ERK inhibitor, enhances the efficacy of PD-1 inhibitor in non-small cell lung carcinoma.
Cordycepin inhibits cell senescence by ameliorating lysosomal dysfunction and inducing autophagy through the AMPK and mTOR-p70S6K pathway.
NLRX1 can counteract innate immune response induced by an external stimulus favoring HBV infection by competitive inhibition of MAVS-RLRs signaling in HepG2-NTCP cells.
Curcumin attenuates Adriamycin-resistance of acute myeloid leukemia by inhibiting the lncRNA HOTAIR/miR-20a-5p/WT1 axis.
FNDC4 acts as an extracellular factor to promote the invasiveness of hepatocellular carcinoma partly via the PI3K/Akt signalling pathway.
Myosin 1f-mediated activation of microglia contributes to the photoreceptor degeneration in a mouse model of retinal detachment.
Serum Level of Tumor-Overexpressed AGR2 Is Significantly Associated with Unfavorable Prognosis of Canine Malignant Mammary Tumors.
Metformin accelerates zebrafish heart regeneration by inducing autophagy.
Extracellular AGR2 activates neighboring fibroblasts through endocytosis and direct binding to β-catenin that requires AGR2 dimerization and adhesion domains.
Adenylyl cyclase 3 regulates osteocyte mechanotransduction and primary cilium.
Targeting MUS81 promotes the anticancer effect of WEE1 inhibitor and immune checkpoint blocking combination therapy via activating cGAS/STING signaling in gastric cancer cells.
Inhibition of immunoproteasome subunit low molecular mass polypeptide 7 with ONX-0914 improves hypoxic-ischemic brain damage via PI3K/Akt signaling.
Thymosin beta 4 alleviates non-alcoholic fatty liver by inhibiting ferroptosis via up-regulation of GPX4.
CDC42EP3 is a key promoter involved in the development and progression of gastric cancer.
Infantile spasms-linked Nedd4-2 mediates hippocampal plasticity and learning via cofilin signaling.
Sesamol supplementation alleviates nonalcoholic steatohepatitis and atherosclerosis in high-fat, high carbohydrate and high-cholesterol diet-fed rats.
Cathepsin B Regulates Mice Granulosa Cells' Apoptosis and Proliferation In Vitro.
Lipophagy deficiency exacerbates ectopic lipid accumulation and tubular cells injury in diabetic nephropathy.
Jian-Pi-Yi-Shen formula enhances perindopril inhibition of chronic kidney disease progression by activation of SIRT3, modulation of mitochondrial dynamics, and antioxidant effects.
AnnexinA7 promotes epithelial-mesenchymal transition by interacting with Sorcin and contributes to aggressiveness in hepatocellular carcinoma.
Quantitatively mapping the interaction of HER2 and EGFR on cell membranes with peptide probes.
RCAN1.4 attenuates renal fibrosis through inhibiting calcineurin-mediated nuclear translocation of NFAT2.
Chitosan oligosaccharides packaged into rat adipose mesenchymal stem cells-derived extracellular vesicles facilitating cartilage injury repair and alleviating osteoarthritis.
Clonal hematopoiesis with JAK2V617F promotes pulmonary hypertension with ALK1 upregulation in lung neutrophils.
Identification of novel key genes associated with the metastasis of prostate cancer based on bioinformatics prediction and validation.
Lnc-DC promotes estrogen independent growth and tamoxifen resistance in breast cancer.
Crocetin suppresses angiogenesis and metastasis through inhibiting sonic hedgehog signaling pathway in gastric cancer.
Circular RNA circUBE2J2 acts as the sponge of microRNA-370-5P to suppress hepatocellular carcinoma progression.
CHD8 safeguards early neuroectoderm differentiation in human ESCs and protects from apoptosis during neurogenesis.
Kinesin family member 2C promotes hepatocellular carcinoma growth and metastasis via activating MEK/ERK pathway.
FGGY carbohydrate kinase domain containing is expressed and alternatively spliced in skeletal muscle and attenuates MAP kinase and Akt signaling.
TM7SF2 regulates cell proliferation and apoptosis by activation of C-Raf/ERK pathway in cervical cancer.
Overexpression of FGF2 delays the progression of osteonecrosis of the femoral head activating the PI3K/Akt signaling pathway.
Palmitoylation targets the calcineurin phosphatase to the phosphatidylinositol 4-kinase complex at the plasma membrane.
Noncanonical Wnt5a signaling regulates tendon stem/progenitor cells senescence.
Human mesenchymal stem cells derived exosomes inhibit the growth of acute myeloid leukemia cells via regulating miR-23b-5p/TRIM14 pathway.
Stem Cell Factor SOX2 Confers Ferroptosis Resistance in Lung Cancer via Upregulation of SLC7A11.
INTS6 promotes colorectal cancer progression by activating of AKT and ERK signaling.
T-lymphoma invasion and metastasis 1 promotes invadopodia formation and is regulated by the PI3K/Akt signaling pathway in hepatocellular carcinoma.
The expression of IFN-β is suppressed by the viral 3D polymerase via its impact on PGAM5 expression during enterovirus D68 infection.
Design, synthesis, and biological evaluation of 2,4-diamino pyrimidine derivatives as potent FAK inhibitors with anti-cancer and anti-angiogenesis activities.
HBeAg mediates inflammatory functions of macrophages by TLR2 contributing to hepatic fibrosis.
SMAD2 regulates testicular development and testosterone synthesis in Hu sheep.
The FOXM1/RNF26/p57 axis regulates the cell cycle to promote the aggressiveness of bladder cancer.
Human m(6)A-mRNA and lncRNA epitranscriptomic microarray reveal function of RNA methylation in hemoglobin H-constant spring disease.
DLEU1 promotes oral squamous cell carcinoma progression by activating interferon-stimulated genes.
17β-Estradiol Enhances Porcine Meiosis Resumption from Autophagy-Induced Gap Junction Intercellular Communications and Connexin 43 Phosphorylation via the MEK/ERK Signaling Pathway.
The interaction of S100A16 and GRP78 actives endoplasmic reticulum stress-mediated through the IRE1α/XBP1 pathway in renal tubulointerstitial fibrosis.
MINDY1 promotes breast cancer cell proliferation by stabilizing estrogen receptor α.
Phase separation of Nur77 mediates celastrol-induced mitophagy by promoting the liquidity of p62/SQSTM1 condensates.
BRCA2 associates with MCM10 to suppress PRIMPOL-mediated repriming and single-stranded gap formation after DNA damage.
Ordered assembly of the cytosolic RNA-sensing MDA5-MAVS signaling complex via binding to unanchored K63-linked poly-ubiquitin chains.
Blockade of T helper 17 cell function ameliorates recurrent Clostridioides difficile infection in mice.
Analyzing the whole-transcriptome profiles of ncRNAs and predicting the competing endogenous RNA networks in cervical cancer cell lines with cisplatin resistance.
FAM83A promotes proliferation and metastasis via Wnt/β-catenin signaling in head neck squamous cell carcinoma.
MiR-20a-5p overexpression prevented diabetic cardiomyopathy via inhibition of cardiomyocyte apoptosis, hypertrophy, fibrosis and JNK/NF-κB signalling pathway.
Vezatin regulates seizures by controlling AMPAR-mediated synaptic activity.
Inactivation of the CIC-DUX4 oncogene through P300/CBP inhibition, a therapeutic approach for CIC-DUX4 sarcoma.
ZFC3H1 prevents RNA trafficking into nuclear speckles through condensation.
PCYT2 synthesizes CDP-glycerol in mammals and reduced PCYT2 enhances the expression of functionally glycosylated α-dystroglycan.
Integrative epigenomic and high-throughput functional enhancer profiling reveals determinants of enhancer heterogeneity in gastric cancer.
Cigarette smoking induces aberrant N(6)-methyladenosine of DAPK2 to promote non-small cell lung cancer progression by activating NF-κB pathway.
Autophagy-dependent ferroptosis contributes to cisplatin-induced hearing loss.
Hsa_circ_0011385 knockdown represses cell proliferation in hepatocellular carcinoma.
Comparative Proteomics of Rat Olfactory Bulb Reveal Insights into Susceptibility and Resiliency to Chronic-stress-induced Depression or Anxiety.
AGTR1 blocker attenuates activation of Tenon's capsule fibroblasts after glaucoma filtration surgery via the NF-κB signaling pathway.
A-24, a steroidal saponin from Allium chinense, induced apoptosis, autophagy and migration inhibition in p53 wild-type and p53-deficient gastric cancer cells.
Diabetic ferroptosis plays an important role in triggering on inflammation in diabetic wound.
Relationships between di-(2-ethylhexyl) phthalate exposure and lipid metabolism in adolescents: Human data and experimental rat model analyses.
Circ-RNF13, as an oncogene, regulates malignant progression of HBV-associated hepatocellular carcinoma cells and HBV infection through ceRNA pathway of circ-RNF13/miR-424-5p/TGIF2.
Flow cytometry allows rapid detection of protein aggregates in cellular and zebrafish models of spinocerebellar ataxia 3.
Elevated β-secretase 1 expression mediates CD4(+) T cell dysfunction via PGE2 signalling in Alzheimer's disease.
Yiqi-Huoxue granule promotes angiogenesis of ischemic myocardium through miR-126/PI3K/Akt axis in endothelial cells.
Long noncoding TMPO antisense RNA 1 promotes hepatocellular carcinoma proliferation and epithelial-mesenchymal transition by targeting the microRNA-126-3p/LRP6/β-catenin axis.
Botrychium schaffneri Underw. extract acts via DIABLO to induce apoptosis and inhibit proliferation of non-small cell lung carcinoma in vitro and in vivo.
Trimethylamine-N-oxide-stimulated hepatocyte-derived exosomes promote inflammation and endothelial dysfunction through nuclear factor-kappa B signaling.
Human umbilical cord mesenchymal stem cells ameliorate acute liver failure by inhibiting apoptosis, inflammation and pyroptosis.
Switch receptor T3/28 improves long-term persistence and antitumor efficacy of CAR-T cells.
Circular RNA circZFPM2 promotes epithelial-mesenchymal transition in endometriosis by regulating miR-205-5p/ZEB1 signalling pathway.
Decreased phosphorylation facilitates the degradation of the endogenous protective molecule c-Ski in vascular smooth muscle cells.
Neuroprotective effect of Na(+) /H(+) exchangers isoform-1 inactivation against 6-hydroxydopamine-induced mitochondrial dysfunction and neuronal apoptosis in Parkinson's disease models.
Long non-coding RNA HOXA-AS3 facilitates the malignancy in colorectal cancer by miR-4319/SPNS2 axis.
Knockdown of ST6Gal-I expression in human hepatocellular carcinoma cells inhibits their exosome-mediated proliferation- and migration-promoting effects.
Activation of HIF1α Rescues the Hypoxic Response and Reverses Metabolic Dysfunction in the Diabetic Heart.
NCAPG, mediated by miR-378a-3p, regulates cell proliferation, cell cycle progression, and apoptosis of oral squamous cell carcinoma through the GSK-3β/β-catenin signaling.
SARS-CoV-2 B.1.617.2 Delta variant replication and immune evasion.
miR-221/222 suppression induced by activation of the cAMP/PKA/CREB1 pathway is required for cAMP-induced bidirectional differentiation of glioma cells.
Effect of mifepristone and lithospermum combination regimen on medical abortion in early pregnancy rats.
Dihydroartemisinin triggers ferroptosis in primary liver cancer cells by promoting and unfolded protein response‑induced upregulation of CHAC1 expression.
Protein kinase G signaling pathway is involved in sympathetically maintained pain by modulating ATP-sensitive potassium channels.
MiR-214-3p plays a protective role in diabetic neuropathic rats by regulating Nav1.3 and TLR4.
Silencing ACTG1 Expression Induces Prostate Cancer Epithelial Mesenchymal Transition Through MAPK/ERK Signaling Pathway.
Selenium-modified calcium phosphate cement can accelerate bone regeneration of osteoporotic bone defect.
Novel WEE2 compound heterozygous mutations identified in patients with fertilization failure or poor fertilization.
Rosamultin from Potentilla anserine L. exhibits nephroprotection and antioxidant activity by regulating the reactive oxygen species/C/EBP homologous protein signaling pathway.
Icariin attenuates renal fibrosis in chronic kidney disease by inhibiting interleukin-1β/transforming growth factor-β-mediated activation of renal fibroblasts.
Platycodon grandiflorum extract attenuates lipopolysaccharide-induced acute lung injury via TLR4/NF-κBp65 pathway in rats.
Vitamin D/VDR regulates peripheral energy homeostasis via central renin-angiotensin system.
Cellular hnRNPAB interacts with avian influenza viral protein PB2 and inhibits virus replication potentially by restricting PB2 mRNA nuclear export and PB2 protein level.
Environmental Pollutant Benzo[a]pyrene Upregulated Long Non-coding RNA HZ07 Inhibits Trophoblast Cell Migration by Inactivating PI3K/AKT/MMP2 Signaling Pathway in Recurrent Pregnancy Loss.
Mapping of pseudouridine residues on cellular and viral transcripts using a novel antibody-based technique.
Japanese encephalitis virus restricts HMGB1 expression to maintain MAPK pathway activation for viral replication.
Drebrin, an actin-binding protein, is required for lens morphogenesis and growth.
SC66 inhibits the proliferation and induces apoptosis of human bladder cancer cells by targeting the AKT/β-catenin pathway.
Casein Kinase II exacerbates rheumatoid arthritis via promoting Th1 and Th17 cell inflammatory responses.
miR‑486‑5p suppresses gastric cancer cell growth and migration through downregulation of fibroblast growth factor 9.
miR-106b-5p upregulation is associated with microglial activation and inflammation in the mouse hippocampus following status epilepticus.
In vivo assessment of molybdenum and cadmium co-induce nephrotoxicity via NLRP3/Caspase-1-mediated pyroptosis in ducks.
Inhibition of Dishevelled-2 suppresses the biological behavior of pancreatic cancer by downregulating Wnt/β-catenin signaling.
An integrated RNA-Seq and network study reveals that valproate inhibited progesterone production in human granulosa cells.
ML-SA1 and SN-2 inhibit endocytosed viruses through regulating TRPML channel expression and activity.
Involvement of REV-ERBα dysregulation and ferroptosis in aristolochic acid I-induced renal injury.
NEDD4 triggers FOXA1 ubiquitination and promotes colon cancer progression under microRNA-340-5p suppression and ATF1 upregulation.
Chitotriosidase attenuates brain inflammation via HDAC3/NF-κB pathway in D-galactose and aluminum-induced rat model with cognitive impairments.
B2M gene expression shapes the immune landscape of lung adenocarcinoma and determines the response to immunotherapy.
Multifunctional MnO(2)-based nanoplatform-induced ferroptosis and apoptosis for synergetic chemoradiotherapy.
Fragile X mental retardation protein-regulated proinflammatory cytokine expression in the spinal cord contributes to the pathogenesis of inflammatory pain induced by complete Freund's adjuvant.
Prenatal EGCG exposure-induced heart mass reduction in adult male mice and underlying mechanisms.
1,3-dichloro-2-propanol induced hepatic lipid accumulation by inhibiting autophagy via AKT/mTOR/FOXO1 pathway in mice.
Perfluorooctane sulfonate induces autophagy-dependent lysosomal membrane permeabilization by weakened interaction between tyrosinated alpha-tubulin and spinster 1.
Varied thyroid disrupting effects of perfluorooctanoic acid (PFOA) and its novel alternatives hexafluoropropylene-oxide-dimer-acid (GenX) and ammonium 4,8-dioxa-3H-perfluorononanoate (ADONA) in vitro.
αCaMKII in the lateral amygdala mediates PTSD-Like behaviors and NMDAR-Dependent LTD.
Liraglutide ameliorates diabetes-associated cognitive dysfunction via rescuing autophagic flux.
Osteopontin improves sensitivity to tyrosine kinase inhibitor in lung adenocarcinoma in vitro by promoting epidermal growth factor receptor phosphorylation.
Selenium-enriched Bifidobacterium longum DD98 attenuates irinotecan-induced intestinal and hepatic toxicity in vitro and in vivo.
Platycodon grandiflorus polysaccharides inhibit Pseudorabies virus replication via downregulating virus-induced autophagy.
Deficiency in WDFY4 reduces the number of CD8(+) T cells via reactive oxygen species-induced apoptosis.
RIP1-dependent linear and nonlinear recruitments of caspase-8 and RIP3 respectively to necrosome specify distinct cell death outcomes.
Synthesis and evaluation of 3-(phenylethynyl)-1,1'-biphenyl-2-carboxylate derivatives as new HIF-1 inhibitors.
DOC-2/DAB2 interactive protein destabilizes c-Myc to impair the growth and self-renewal of colon tumor-repopulating cells.
HIF2α promotes tumour growth in clear cell renal cell carcinoma by increasing the expression of NUDT1 to reduce oxidative stress.
Protocatechuic aldehyde protects cardiomycoytes against ischemic injury via regulation of nuclear pyruvate kinase M2.
Ceruloplasmin overexpression is associated with oncogenic pathways and poorer survival rates in clear-cell renal cell carcinoma.
LINC00370 modulates miR-222-3p-RGS4 axis to protect against osteoporosis progression.
CD38 deficiency up-regulated IL-1β and MCP-1 through TLR4/ERK/NF-κB pathway in sepsis pulmonary injury.
Direct Activation of Endothelial Cells by SARS-CoV-2 Nucleocapsid Protein Is Blocked by Simvastatin.
Discovery of Phenolic Glycoside from Hyssopus cuspidatus Attenuates LPS-Induced Inflammatory Responses by Inhibition of iNOS and COX-2 Expression through Suppression of NF-κB Activation.
HSD17B6 downregulation predicts poor prognosis and drives tumor progression via activating Akt signaling pathway in lung adenocarcinoma.
High throughput sequencing of whole transcriptome and construct of ceRNA regulatory network in RD cells infected with enterovirus D68.
LPS-induced macrophage HMGB1-loaded extracellular vesicles trigger hepatocyte pyroptosis by activating the NLRP3 inflammasome.
Total glycosides from Eucommia ulmoides seed promoted osteogenic differentiation of adipose-derived mesenchymal stem cells and bone formation in ovariectomized rats through regulating Notch signaling pathway.
Erythromycin reduces nasal inflammation by inhibiting immunoglobulin production, attenuating mucus secretion, and modulating cytokine expression.
Increased expression of TAZ and associated upregulation of PD-L1 in cervical cancer.
GSK-3β manipulates ferroptosis sensitivity by dominating iron homeostasis.
Long non-coding RNA SNHG1 promotes fibroblast-to-myofibroblast transition during the development of pulmonary fibrosis induced by silica particles exposure.
Taxifolin retards the D-galactose-induced aging process through inhibiting Nrf2-mediated oxidative stress and regulating the gut microbiota in mice.
Cardamonin inhibits osteogenic differentiation of human valve interstitial cells and ameliorates aortic valve calcification via interfering in the NF-κB/NLRP3 inflammasome pathway.
MICU3 regulates mitochondrial Ca(2+)-dependent antioxidant response in skeletal muscle aging.
LAGE3 promoted cell proliferation, migration, and invasion and inhibited cell apoptosis of hepatocellular carcinoma by facilitating the JNK and ERK signaling pathway.
NEDD4L-induced ubiquitination mediating UBE2T degradation inhibits progression of lung adenocarcinoma via PI3K-AKT signaling.
Downregulation of miR-29c promotes muscle wasting by modulating the activity of leukemia inhibitory factor in lung cancer cachexia.
Bone morphogenetic protein 9 enhances osteogenic and angiogenic responses of human amniotic mesenchymal stem cells cocultured with umbilical vein endothelial cells through the PI3K/AKT/m-TOR signaling pathway.
Sesquiterpene Lactones from Sigesbeckia glabrescens Possessing Potent Anti-inflammatory Activity by Directly Binding to IKKα/β.
Oxidative stress transforms 3CLpro into an insoluble and more active form to promote SARS-CoV-2 replication.
Reciprocal regulation of LOXL2 and HIF1α drives the Warburg effect to support pancreatic cancer aggressiveness.
Structure-Based Discovery of Potent CARM1 Inhibitors for Solid Tumor and Cancer Immunology Therapy.
The structural basis for the phospholipid remodeling by lysophosphatidylcholine acyltransferase 3.
Urinary peptidomics reveals proteases involved in idiopathic membranous nephropathy.
miR-30b-5p inhibits proliferation, invasion, and migration of papillary thyroid cancer by targeting GALNT7 via the EGFR/PI3K/AKT pathway.
Extracellular vesicles derived from hypoxia-preconditioned olfactory mucosa mesenchymal stem cells enhance angiogenesis via miR-612.
Cadmium attenuates testosterone synthesis by promoting ferroptosis and blocking autophagosome-lysosome fusion.
IRF3-binding lncRNA-ISIR strengthens interferon production in viral infection and autoinflammation.
Blood-Based Epigenetic Markers of FKBP5 Gene Methylation in Patients With Dilated Cardiomyopathy.
The Y14-p53 regulatory circuit in megakaryocyte differentiation and thrombocytopenia.
Capping protein regulates endosomal trafficking by controlling F-actin density around endocytic vesicles and recruiting RAB5 effectors.
TBHQ attenuates ferroptosis against 5-fluorouracil-induced intestinal epithelial cell injury and intestinal mucositis via activation of Nrf2.
Indole-3-Propionic Acid, a Functional Metabolite of Clostridium sporogenes, Promotes Muscle Tissue Development and Reduces Muscle Cell Inflammation.
Inhibition of DTYMK significantly restrains the growth of HCC and increases sensitivity to oxaliplatin.
Identification of proximal SUMO-dependent interactors using SUMO-ID.
Shikonin Induced Program Cell Death through Generation of Reactive Oxygen Species in Renal Cancer Cells.
Fluoride Stimulates Anxiety- and Depression-like Behaviors Associated with SIK2-CRTC1 Signaling Dysfunction.
Dendrobium officinale Polysaccharide Alleviates Intestinal Inflammation by Promoting Small Extracellular Vesicle Packaging of miR-433-3p.
Knockdown of circFOXO3 ameliorates cigarette smoke-induced lung injury in mice.
Knockout of mafba Causes Inner-Ear Developmental Defects in Zebrafish via the Impairment of Proliferation and Differentiation of Ionocyte Progenitor Cells.
Inhibition of DCLK1 with DCLK1-IN-1 Suppresses Renal Cell Carcinoma Invasion and Stemness and Promotes Cytotoxic T-Cell-Mediated Anti-Tumor Immunity.
Remodelling of gut microbiota by Berberine attenuates trimethylamine N-oxide-induced platelet hyperreaction and thrombus formation.
STOML2 interacts with PHB through activating MAPK signaling pathway to promote colorectal Cancer proliferation.
Babao Dan is a robust anti-tumor agent via inhibiting wnt/β-catenin activation and cancer cell stemness.
Single-Cell Analyses Reveal Mechanisms of Cancer Stem Cell Maintenance and Epithelial-Mesenchymal Transition in Recurrent Bladder Cancer.
(-)-Epigallocatechin-3-gallate mitigates cyclophosphamide-induced intestinal injury by modulating the tight junctions, inflammation and dysbiosis in mice.
SARS-CoV-2 inhibits induction of the MHC class I pathway by targeting the STAT1-IRF1-NLRC5 axis.
Inhibition of METTL3/m6A/miR126 promotes the migration and invasion of endometrial stromal cells in endometriosis†.
PRMT1-mediated EZH2 methylation promotes breast cancer cell proliferation and tumorigenesis.
TM9SF4 is a novel regulator in lineage commitment of bone marrow mesenchymal stem cells to either osteoblasts or adipocytes.
LRG1 destabilizes tumor vessels and restricts immunotherapeutic potency.
Discovery of a Dual Tubulin and Poly(ADP-Ribose) Polymerase-1 Inhibitor by Structure-Based Pharmacophore Modeling, Virtual Screening, Molecular Docking, and Biological Evaluation.
The Large GTPase, GBP-2, Regulates Rho Family GTPases to Inhibit Migration and Invadosome Formation in Breast Cancer Cells.
Deletion of miR-15a inhibited glioma development via targeting Smad7 and inhibiting EMT pathway.
Resveratrol induces proliferation in preosteoblast cell MC3T3-E1 via GATA-1 activating autophagy.
Mof acetyltransferase inhibition ameliorates glucose intolerance and islet dysfunction of type 2 diabetes via targeting pancreatic α-cells.
Isorhapontigenin (ISO) inhibits EMT through FOXO3A/METTL14/VIMENTIN pathway in bladder cancer cells.
Sodium cantharidate induces Apoptosis in breast cancer cells by regulating energy metabolism via the protein phosphatase 5-p53 axis.
Neurotoxicity of a pyrethroid pesticide deltamethrin is associated with the imbalance in proteolytic systems caused by mitophagy activation and proteasome inhibition.
Comparative analysis of the MyTH4-FERM myosins reveals insights into the determinants of actin track selection in polarized epithelia.
Muse Cells Have Higher Stress Tolerance than Adipose Stem Cells due to the Overexpression of the CCNA2 Gene.
A novel mutation in NF1 gene of patient with Neurofibromatosis type 1: A case report and functional study.
Trojan Horse Delivery of 4,4'-Dimethoxychalcone for Parkinsonian Neuroprotection.
Aldehyde Dehydrogenase 2 Mediates Alcohol-Induced Colorectal Cancer Immune Escape through Stabilizing PD-L1 Expression.
Overproduced CPSF4 Promotes Cell Proliferation and Invasion via PI3K-AKT Signaling Pathway in Oral Squamous Cell Carcinoma.
Elevated type I interferon responses potentiate metabolic dysfunction, inflammation, and accelerated aging in mtDNA mutator mice.
Centrosomal protein FOR20 knockout mice display embryonic lethality and left-right patterning defects.
The Long Noncoding RNA Hepatocyte Nuclear Factor 4α Antisense RNA 1 Negatively Regulates Cytochrome P450 Enzymes in Huh7 Cells via Histone Modifications.
MiR-195-5p inhibits proliferation and invasion of nerve cells in Hirschsprung disease by targeting GFRA4.
TGIF1 plays a carcinogenic role in esophageal squamous cell carcinoma through the Wnt/β‑catenin and Akt/mTOR signaling pathways.
LINC01816 promotes the migration, invasion and epithelial‑mesenchymal transition of thyroid carcinoma cells by sponging miR‑34c‑5p and regulating CRABP2 expression levels.
Methylation gene KCNC1 is associated with overall survival in patients with seminoma.
Novel gene-encoded intermolecular FRET sensor for tracking glycosylation of CD147 in living cells.
Relevance of CYP3A5 Expression on the Clinical Outcome of Patients With Renal Cell Carcinoma.
Acetaldehyde Dehydrogenase 2 regulates HMG-CoA reductase stability and cholesterol synthesis in the liver.
Long non-coding RNA SMASR inhibits the EMT by negatively regulating TGF-β/Smad signaling pathway in lung cancer.
Antiangiogenic effect of arsenic trioxide in HUVECs by FoxO3a-regulated autophagy.
Glucose-dependent insulinotropic polypeptide modifies adipose plasticity and promotes beige adipogenesis of human omental adipose-derived stem cells.
L-leucine promotes axonal outgrowth and regeneration via mTOR activation.
TUFM is involved in Alzheimer's disease-like pathologies that are associated with ROS.
BALB/c mice infected with Angiostrongylus cantonensis: A new model for demyelination in the brain.
Porcine TRIM21 RING-finger E3 ubiquitin ligase is essential for anti-PRRSV activity.
RAGE: A potential therapeutic target during FGF1 treatment of diabetes-mediated liver injury.
Zebrafish hhatla is involved in cardiac hypertrophy.
Podocyte apoptosis in diabetic nephropathy by BASP1 activation of the p53 pathway via WT1.
LIMIT is an immunogenic lncRNA in cancer immunity and immunotherapy.
Exosomal microRNA-301a-3p promotes the proliferation and invasion of nasopharyngeal carcinoma cells by targeting BTG1 mRNA.
Regulatory role of the TLR4/JNK signaling pathway in sepsis‑induced myocardial dysfunction.
Protective effects of curcumin against rat intestinal inflammation‑related motility disorders.
The DpdtbA induced EMT inhibition in gastric cancer cell lines was through ferritinophagy-mediated activation of p53 and PHD2/hif-1α pathway.
Role of vasodilator-stimulated phosphoprotein in RANKL-differentiated murine macrophage RAW264.7 cells: Modulation of NF-κB, c-Fos and NFATc1 transcription factors.
Synergistic effects of olaparib combined with ERCC1 on the sensitivity of cisplatin in non-small cell lung cancer.
Promoting roles of KLF5 in myocardial infarction in mice involving microRNA-27a suppression and the following GFPT2/TGF-β/Smad2/3 axis activation.
Gut-Lung Dysbiosis Accompanied by Diabetes Mellitus Leads to Pulmonary Fibrotic Change through the NF-κB Signaling Pathway.
Integrated transcriptomics and epigenomics reveal chamber-specific and species-specific characteristics of human and mouse hearts.
Knockdown of the mRNA encoding the ribosomal protein eL38 in mammalian cells causes a substantial reorganization of genomic transcription.
Mitochondrial TXN2 attenuates amyloidogenesis via selective inhibition of BACE1 expression.
α-synuclein abnormalities trigger focal tau pathology, spreading to various brain areas in Parkinson disease.
Toxicological and physiological effects of successive exposure to ochratoxin A at food regulatory limits.
Identification of differentially expressed proteins between fused and open sutures in sagittal nonsyndromic craniosynostosis during suture development by quantitative proteomic analysis.
Qingjie Fuzheng Granule suppresses lymphangiogenesis in colorectal cancer via the VEGF-C/VEGFR-3 dependent PI3K/AKT pathway.
The Kidney-Related Effects of Polystyrene Microplastics on Human Kidney Proximal Tubular Epithelial Cells HK-2 and Male C57BL/6 Mice.
The clinical significance, prognostic value and biological role of lncRNA LINC01793 in oral squamous cell carcinoma.
Tracing production instability in a clonally derived CHO cell line using single-cell transcriptomics.
The critical role of ZP genes in female infertility characterized by empty follicle syndrome and oocyte degeneration.
SMYD3-PARP16 axis accelerates unfolded protein response and mediates neointima formation.
PD-L1 combined with HDAC9 is a useful prognostic predictor in hepatocellular carcinoma.
miR-140-3p inhibits colorectal cancer progression and its liver metastasis by targeting BCL9 and BCL2.
The near-infrared dye IR-61 restores erectile function in a streptozotocin-induced diabetes model via mitochondrial protection.
G-Protein-coupled Estrogen Receptor 1 Agonist G-1 Perturbs Sunitinib Resistance-related Phosphoproteomic Signatures in Renal Cell Carcinoma.
Silencing TAK1 reduces MAPKs-MMP2/9 expression to reduce inflammation-driven neurohistological disruption post spinal cord injury.
BCL7C suppresses ovarian cancer growth by inactivating mutant p53.
Time-resolved proteomics profiling of the ciliary Hedgehog response.
FIT2 organizes lipid droplet biogenesis with ER tubule-forming proteins and septins.
miR-132 mediates cell permeability and migration by targeting occludin in high-glucose -induced ARPE-19 cells.
Neocortex- and hippocampus-specific deletion of Gabrg2 causes temperature-dependent seizures in mice.
Vertebrate cells differentially interpret ciliary and extraciliary cAMP.
Mitocytosis, a migrasome-mediated mitochondrial quality-control process.
SEC61G promotes breast cancer development and metastasis via modulating glycolysis and is transcriptionally regulated by E2F1.
Protective Effects of Fucoxanthin on Hydrogen Peroxide-Induced Calcification of Heart Valve Interstitial Cells.
The SUN1-SPDYA interaction plays an essential role in meiosis prophase I.
STIP1 knockdown suppresses colorectal cancer cell proliferation, migration and invasion by inhibiting STAT3 pathway.
circ-PTK2 (hsa_circ_0008305) regulates the pathogenic processes of ovarian cancer via miR-639 and FOXC1 regulatory cascade.
Activation of the STAT3 Signaling Pathway by the RNA-Dependent RNA Polymerase Protein of Arenavirus.
OTUD7B stabilizes estrogen receptor α and promotes breast cancer cell proliferation.
Splicing factor SRSF6 mediates pleural fibrosis.
The viral restriction factor tetherin/BST2 tethers cytokinetic midbody remnants to the cell surface.
Downregulation of CD151 restricts VCAM-1 mediated leukocyte infiltration to reduce neurobiological injuries after experimental stroke.
miR-338-3p inhibits autophagy in a rat model of allergic rhinitis after PM2.5 exposure through AKT/mTOR signaling by targeting UBE2Q1.
Long non-coding RNA SNHG14 aggravates LPS-induced acute kidney injury through regulating miR-495-3p/HIPK1.
SAA1/TLR2 axis directs chemotactic migration of hepatic stellate cells responding to injury.
Amphiphysin I cleavage by asparagine endopeptidase leads to tau hyperphosphorylation and synaptic dysfunction.
Ganoderma lucidum stimulates autophagy-dependent longevity pathways in Caenorhabditis elegans and human cells.
LncRNA CD27-AS1 promotes acute myeloid leukemia progression through the miR-224-5p/PBX3 signaling circuit.
Heme cytotoxicity is the consequence of endoplasmic reticulum stress in atherosclerotic plaque progression.
LncRNA ZNF674-AS1 regulates granulosa cell glycolysis and proliferation by interacting with ALDOA.
YTHDF1 Promotes Gastric Carcinogenesis by Controlling Translation of FZD7.
BMI1 regulates multiple myeloma-associated macrophage's pro-myeloma functions.
Asenapine maleate inhibits angiotensin II-induced proliferation and activation of cardiac fibroblasts via the ROS/TGFβ1/MAPK signaling pathway.
Ferritin disorder in the plasma and hippocampus associated with major depressive disorder.
Hyperactivation of HER2-SHCBP1-PLK1 axis promotes tumor cell mitosis and impairs trastuzumab sensitivity to gastric cancer.
Endothelial genetic deletion of CD147 induces changes in the dual function of the blood-brain barrier and is implicated in Alzheimer's disease.
Interactions between Autophagy, Proinflammatory Cytokines, and Apoptosis in Neuropathic Pain: Granulocyte Colony Stimulating Factor as a Multipotent Therapy in Rats with Chronic Constriction Injury.
Antifungal Activity of Quinofumelin against Fusarium graminearum and Its Inhibitory Effect on DON Biosynthesis.
Zuojin Pill ameliorates chronic atrophic gastritis induced by MNNG through TGF-β1/PI3K/Akt axis.
Formation of fibrin at sights of conceptus adhesion in the ewe.
Tryptanthrin Regulates Vascular Smooth Muscle Cell Phenotypic Switching in Atherosclerosis by AMP-Activated Protein Kinase/Acetyl-CoA Carboxylase Signaling Pathway.
LRRC4 functions as a neuron-protective role in experimental autoimmune encephalomyelitis.
Psoralidin, a major component of Psoraleae Fructus, induces inflammasome activation and idiosyncratic liver injury.
Hypoxia enhances the production and antitumor effect of exosomes derived from natural killer cells.
Arginine methyltransferase PRMT5 negatively regulates cGAS-mediated antiviral immune response.
The cryo-EM structure of an ERAD protein channel formed by tetrameric human Derlin-1.
Trim47 overexpression correlates with poor prognosis in gastric cancer.
Decreased miR-214-3p activates NF-κB pathway and aggravates osteoarthritis progression.
Total flavone extract from Ampelopsis megalophylla induces apoptosis in the MCF‑7 cell line.
Biological testing of chitosan-collagen-based porous scaffolds loaded with PLGA/Triamcinolone microspheres for ameliorating endoscopic dissection-related stenosis in oesophagus.
Sirtuin 1 ameliorates defenestration in hepatic sinusoidal endothelial cells during liver fibrosis via inhibiting stress-induced premature senescence.
RNA m6A Modification Alteration by Black Phosphorus Quantum Dots Regulates Cell Ferroptosis: Implications for Nanotoxicological Assessment.
miR‑106b‑5p targeting SIX1 inhibits TGF‑β1‑induced pulmonary fibrosis and epithelial‑mesenchymal transition in asthma through regulation of E2F1.
VSP‑17 suppresses the migration and invasion of triple‑negative breast cancer cells through inhibition of the EMT process via the PPARγ/AMPK signaling pathway.
Nucleolar and spindle‑associated protein 1 promotes non‑small cell lung cancer progression and serves as an effector of myocyte enhancer factor 2D.
20(S)-ginsenoside Rh2 induces caspase-dependent promyelocytic leukemia-retinoic acid receptor A degradation in NB4 cells via Akt/Bax/caspase9 and TNF-α/caspase8 signaling cascades.
Abnormal cGMP-dependent protein kinase I-mediated decidualization in preeclampsia.
KLF4 initiates sustained YAP activation to promote renal fibrosis in mice after ischemia-reperfusion kidney injury.
miR-30a-5p Inhibits Epithelial-to-Mesenchymal Transition by Targeting CDK6 in Nasal Polyps.
Oncogenic AURKA-enhanced N(6)-methyladenosine modification increases DROSHA mRNA stability to transactivate STC1 in breast cancer stem-like cells.
NFAT Overexpression Correlates with CA72-4 and Poor Prognosis of Ovarian Clear-Cell Carcinoma Subtype.
TRF2 recruits nucleolar protein TCOF1 to coordinate telomere transcription and replication.
Histone deacetylase 3 aberration inhibits Klotho transcription and promotes renal fibrosis.
Activation of NRF2/FPN1 pathway attenuates myocardial ischemia-reperfusion injury in diabetic rats by regulating iron homeostasis and ferroptosis.
Chondrocyte ferroptosis contribute to the progression of osteoarthritis.
Gambogic acid ameliorates high glucose- and palmitic acid-induced inflammatory response in ARPE-19 cells via activating Nrf2 signaling pathway: ex vivo.
AIMP3 inhibits cell growth and metastasis of lung adenocarcinoma through activating a miR-96-5p-AIMP3-p53 axis.
CRKL promotes hepatocarcinoma through enhancing glucose metabolism of cancer cells via activating PI3K/Akt.
P53 regulation of osteoblast differentiation is mediated through specific microRNAs.
SHARPIN stabilizes β-catenin through a linear ubiquitination-independent manner to support gastric tumorigenesis.
α5-nAChR and survivin: Two potential biological targets in lung adenocarcinoma.
Zenglv Fumai Granule protects cardiomyocytes against hypoxia/reoxygenation-induced apoptosis via inhibiting TRIM28 expression.
Genetic response to low‑intensity ultrasound on mouse ST2 bone marrow stromal cells.
Emodin enhances cisplatin sensitivity in non-small cell lung cancer through Pgp downregulation.
Decreased Expression of Heat Shock Protein 47 Is Associated with T-2 Toxin and Low Selenium-Induced Matrix Degradation in Cartilages of Kashin-Beck Disease.
Two loss-of-function ANKRD11 variants in Chinese patients with short stature and a possible molecular pathway.
Nuciferine protects against folic acid-induced acute kidney injury by inhibiting ferroptosis.
JMJD6 negatively regulates cytosolic RNA induced antiviral signaling by recruiting RNF5 to promote activated IRF3 K48 ubiquitination.
CITED4 mediates proliferation, apoptosis and steroidogenesis of Hu sheep granulosa cells in vitro.
Babao Dan improves neurocognitive function by inhibiting inflammation in clinical minimal hepatic encephalopathy.
DZNep attenuates allergic airway inflammation in an ovalbumin-induced murine model.
Radiotherapy programs neutrophils to an antitumor phenotype by inducing mesenchymal-epithelial transition.
Annexin A7 and JNK knockdown suppress the lymphatic metastasis potential of hepatocellular carcinoma cells: Possible contributions of ATF2 and sequence-related lncRNA NONMMUT114121.1.
Plumbagin, a Biomolecule with (Anti)Osteoclastic Properties.
Identification of Overexpressed Genes in Malignant Pleural Mesothelioma.
Epigenetically modulated miR-1224 suppresses the proliferation of HCC through CREB-mediated activation of YAP signaling pathway.
Circular RNA RBPMS inhibits bladder cancer progression via miR-330-3p/RAI2 regulation.
Long noncoding RNA SMUL suppresses SMURF2 production-mediated muscle atrophy via nonsense-mediated mRNA decay.
Design, synthesis and pharmacological evaluation of bicyclic and tetracyclic pyridopyrimidinone analogues as new KRAS(G12C) inhibitors.
miR-98-5p protects against cerebral ischemia/reperfusion injury through anti-apoptosis and anti-oxidative stress in mice.
Hepatic HuR protects against the pathogenesis of non-alcoholic fatty liver disease by targeting PTEN.
HIF-1/AKT Signaling-Activated PFKFB2 Alleviates Cardiac Dysfunction and Cardiomyocyte Apoptosis in Response to Hypoxia.
Involvement of HECTD1 in LPS-induced astrocyte activation via σ-1R-JNK/p38-FOXJ2 axis.
LMNB2 promotes the progression of colorectal cancer by silencing p21 expression.
Let-7i-5p enhances cell proliferation, migration and invasion of ccRCC by targeting HABP4.
Parkinson's Disease Causative Mutation in Vps35 Disturbs Tetherin Trafficking to Cell Surfaces and Facilitates Virus Spread.
Glutathione S-transferase Pi (Gstp) proteins regulate neuritogenesis in the developing cerebral cortex.
Metabolomics analysis delineates the therapeutic effects of Huangqi decoction and astragalosides on α-naphthylisothiocyanate (ANIT) -induced cholestasis in rats.
Crocetin ameliorates chronic restraint stress-induced depression-like behaviors in mice by regulating MEK/ERK pathways and gut microbiota.
NMR-Based Metabolomic Analysis for the Effects of α-Ketoglutarate Supplementation on C2C12 Myoblasts in Different Energy States.
Membrane-cytoplasm translocation of annexin A4 is involved in the metastasis of colorectal carcinoma.
Acoustic Droplet Vitrification Method for High-Efficiency Preservation of Rare Cells.
CircRNA RSF1 regulated ox-LDL induced vascular endothelial cells proliferation, apoptosis and inflammation through modulating miR-135b-5p/HDAC1 axis in atherosclerosis.
Tanshinone IIA combined with CsA inhibit myocardial cell apoptosis induced by renal ischemia-reperfusion injury in obese rats.
VPS34 regulates dynamin to determine the endocytosis of mitochondria-targeted zinc oxide nanoparticles in human osteosarcoma cells.
Identification of HOXA10 target genes in human endometrial stromal cells by RNA-seq analysis.
Clostridium Butyricum ZJU-F1 Benefits the Intestinal Barrier Function and Immune Response Associated with Its Modulation of Gut Microbiota in Weaned Piglets.
TagBiFC technique allows long-term single-molecule tracking of protein-protein interactions in living cells.
HDAC11 inhibition disrupts porcine oocyte meiosis via regulating α-tubulin acetylation and histone modifications.
CircSPI1 acts as an oncogene in acute myeloid leukemia through antagonizing SPI1 and interacting with microRNAs.
The MEK1/2 Pathway as a Therapeutic Target in High-Grade Serous Ovarian Carcinoma.
E3 Ubiquitin Ligase ASB17 Promotes Apoptosis by Ubiquitylating and Degrading BCLW and MCL1.
Kaempferol Reverses Aerobic Glycolysis via miR-339-5p-Mediated PKM Alternative Splicing in Colon Cancer Cells.
TMEM119 facilitates ovarian cancer cell proliferation, invasion, and migration via the PDGFRB/PI3K/AKT signaling pathway.
Rab26 suppresses migration and invasion of breast cancer cells through mediating autophagic degradation of phosphorylated Src.
Astrocytic ApoE reprograms neuronal cholesterol metabolism and histone-acetylation-mediated memory.
TBC1D16 predicts chemosensitivity and prognosis in adult acute myeloid leukemia (AML) patients.
GR/NF-κB signaling pathway regulates hippocampal inflammatory responses in diabetic rats with chronic unpredictable mild stress.
PDX models reflect the proteome landscape of pediatric acute lymphoblastic leukemia but divert in select pathways.
Thrombin inhibitor argatroban modulates bone marrow stromal cells behaviors and promotes osteogenesis through canonical Wnt signaling.
Identification and functional analysis of senescence-associated secretory phenotype of premature senescent hepatocytes induced by hexavalent chromium.
The role of Se content in improving anti-tumor activities and its potential mechanism for selenized Artemisia sphaerocephala polysaccharides.
MiR-1290 promotes myoblast differentiation and protects against myotube atrophy via Akt/p70/FoxO3 pathway regulation.
Perilipin 5 ameliorates high-glucose-induced podocyte injury via Akt/GSK-3β/Nrf2-mediated suppression of apoptosis, oxidative stress, and inflammation.
Citrus Alkaline Extracts Inhibit Senescence of A549 Cells to Alleviate Pulmonary Fibrosis via the β-Catenin/P53 Pathway.
Synergistic effects of AAGL and anti-PD-1 on hepatocellular carcinoma through lymphocyte recruitment to the liver.
Lnc13728 facilitates human mesenchymal stem cell adipogenic differentiation via positive regulation of ZBED3 and downregulation of the WNT/β-catenin pathway.
Novel IMB16-4 Compound Loaded into Silica Nanoparticles Exhibits Enhanced Oral Bioavailability and Increased Anti-Liver Fibrosis In Vitro.
SRP54 mutations induce congenital neutropenia via dominant-negative effects on XBP1 splicing.
Isoliquiritigenin Reverses Epithelial-Mesenchymal Transition Through Modulation of the TGF-β/Smad Signaling Pathway in Endometrial Cancer.
MAGI1 inhibits the AMOTL2/p38 stress pathway and prevents luminal breast tumorigenesis.
The role of irreversible electroporation in promoting M1 macrophage polarization via regulating the HMGB1-RAGE-MAPK axis in pancreatic cancer.
Positive regulation of Type III secretion effectors and virulence by RyhB paralogs in Salmonella enterica serovar Enteritidis.
Downregulation of lncRNA ZNF582-AS1 due to DNA hypermethylation promotes clear cell renal cell carcinoma growth and metastasis by regulating the N(6)-methyladenosine modification of MT-RNR1.
Endogenous conversion of n-6 to n-3 polyunsaturated fatty acids facilitates the repair of cardiotoxin-induced skeletal muscle injury in fat-1 mice.
A novel function of African Swine Fever Virus pE66L in inhibition of host translation by the PKR/eIF2α pathway.
Long Noncoding RNA DUXAP8 Promotes Pancreatic Carcinoma Cell Migration and Invasion Via Pathway by miR-448/WTAP/Fak Signaling Axis.
TMEM2 binds to CSNK2A3 to inhibit HBV infection via activation of the JAK/STAT pathway.
Cancer-associated fibroblasts promote the survival of irradiated nasopharyngeal carcinoma cells via the NF-κB pathway.
Prematurity blunts the insulin- and amino acid-induced stimulation of translation initiation and protein synthesis in skeletal muscle of neonatal pigs.
Endoplasmic Reticulum Stress-Mediated p62 Downregulation Inhibits Apoptosis via c-Jun Upregulation.
Contributions of HO-1-Dependent MAPK to Regulating Intestinal Barrier Disruption.
Cadmium and molybdenum co-induce pyroptosis via ROS/PTEN/PI3K/AKT axis in duck renal tubular epithelial cells.
Tubeimoside I promotes angiogenesis via activation of eNOS-VEGF signaling pathway.
Benzo[a]pyrene induces fibrotic changes and impairs differentiation in lung stem cells.
Circulating Exosomes From Patients With Graves' Disease Induce an Inflammatory Immune Response.
METTL3-mediated m(6)A modification regulates cell cycle progression of dental pulp stem cells.
CRISPR/Cas9-mediated knockin of human factor IX into swine factor IX locus effectively alleviates bleeding in hemophilia B pigs.
Iguratimod-encapsulating PLGA-NPs induce human multiple myeloma cell death via reactive oxygen species and Caspase-dependent signalling.
Tumor protein D52 promotes breast cancer proliferation and migration via the long non-coding RNA NEAT1/microRNA-218-5p axis.
Overexpression of lipoic acid synthase gene alleviates diabetic nephropathy of Lepr(db/db) mice.
Vitexin exerts protective effects against calcium oxalate crystal-induced kidney pyroptosis in vivo and in vitro.
PFKP facilitates ATG4B phosphorylation during amino acid deprivation-induced autophagy.
Suberoylanilide Hydroxamic Acid (SAHA) Reduces Fibrosis Markers and Deactivates Human Stellate Cells via the Epithelial-Mesenchymal Transition (EMT).
Human SND2 mediates ER targeting of GPI-anchored proteins with low hydrophobic GPI attachment signals.
A phase-separated nuclear GBPL circuit controls immunity in plants.
Carbon monoxide alleviates senescence in diabetic nephropathy by improving autophagy.
Attenuation of the upregulation of NF‑κB and AP‑1 DNA‑binding activities induced by tunicamycin or hypoxia/reoxygenation in neonatal rat cardiomyocytes by SERCA2a overexpression.
Long non‑coding RNA MIR4435‑2HG promotes the progression of head and neck squamous cell carcinoma by regulating the miR‑383‑5p/RBM3 axis.
[Retracted] Hypoxia‑induced mitochondrial translocation of DNM1L increases mitochondrial fission and triggers mPTP opening in HCC cells via activation of HK2.
Drug-repositioning screening identified fludarabine and risedronic acid as potential therapeutic compounds for malignant pleural mesothelioma.
Generation of A Stable GFP-reporter Zika Virus System for High-throughput Screening of Zika Virus Inhibitors.
Differentially expressed proteins identified by TMT proteomics analysis in children with verrucous epidermal naevi.
Mutual dependency between lncRNA LETN and protein NPM1 in controlling the nucleolar structure and functions sustaining cell proliferation.
Generation and identification of endothelial-specific Hrh2 knockout mice.
Comprehensive interactome analysis of the spike protein of swine acute diarrhea syndrome coronavirus.
Targeting IDH1/2 mutant cancers with combinations of ATR and PARP inhibitors.
Matrix stiffness-mediated effects on macrophages polarization and their LOXL2 expression.
Lipotoxicity suppresses the synthesis of growth hormone in pituitary somatotrophs via endoplasmic reticulum stress.
Rescue of maternal immune activation-induced behavioral abnormalities in adult mouse offspring by pathogen-activated maternal T(reg) cells.
Crosstalk between the COX2-PGE2-EP4 signaling pathway and primary cilia in osteoblasts after mechanical stimulation.
Acvr1 deletion in osteoblasts impaired mandibular bone mass through compromised osteoblast differentiation and enhanced sRANKL-induced osteoclastogenesis.
SOD3 deficiency induces liver fibrosis by promoting hepatic stellate cell activation and epithelial-mesenchymal transition.
Dioscin inhibits SCC15 cell proliferation via the RASSF1A/MST2/YAP axis.
SEC61G is upregulated and required for tumor progression in human kidney cancer.
Salidroside overcomes dexamethasone resistance in T-acute lymphoblastic leukemia cells.
Ginkgo biloba delays light-induced photoreceptor degeneration through antioxidant and antiapoptotic properties.
Oncogenic WIP1 phosphatase attenuates the DNA damage response and sensitizes p53 mutant Jurkat cells to apoptosis.
PHD Finger Protein 19 Promotes Cardiac Hypertrophy via Epigenetically Regulating SIRT2.
DEK is highly expressed in breast cancer and is associated with malignant phenotype and progression.
Long noncoding RNA PM maintains cerebellar synaptic integrity and Cbln1 activation via Pax6/Mll1-mediated H3K4me3.
Ketoplatin in triple-negative breast cancer cells MDA-MB-231: High efficacy and low toxicity, and positive impact on inflammatory microenvironment.
Virus-inducible IGFALS facilitates innate immune responses by mediating IRAK1 and TRAF6 activation.
T-17, a spirostanol saponin, inhibits p53-independent proliferation and p53-dependent migration of gastric cancer cells.
SNX-3 mediates retromer-independent tubular endosomal recycling by opposing EEA-1-facilitated trafficking.
NIR-II Absorbing Semiconducting Polymer-Triggered Gene-Directed Enzyme Prodrug Therapy for Cancer Treatment.
PPARα agonist WY-14,643 enhances ethanol metabolism in mice: Role of catalase.
Paricalcitol inhibits oxidative stress-induced cell senescence of the bile duct epithelium dependent on modulating Sirt1 pathway in cholestatic mice.
Unbiased proteomic screening identifies a novel role for the E3 ubiquitin ligase Nedd4-2 in translational suppression during ER stress.
ALS-causing SOD1 mutants regulate occludin phosphorylation/ubiquitination and endocytic trafficking via the ITCH/Eps15/Rab5 axis.
Prohibitin regulates mTOR pathway via interaction with FKBP8.
AMD3465 (hexahydrobromide) rescues the MG63 osteoblasts against the apoptosis induced by high glucose.
Gu-Ben-Fang-Xiao decoction modulates lipid metabolism by activating the AMPK pathway in asthma remission.
Nuclear m(6)A reader YTHDC1 regulates the scaffold function of LINE1 RNA in mouse ESCs and early embryos.
Design, synthesis and biological evaluation of anilide (dicarboxylic acid) shikonin esters as antitumor agents through targeting PI3K/Akt/mTOR signaling pathway.
C/EBPδ drives key endocrine signals in the human amnion at parturition.
HYD-PEP06 suppresses hepatocellular carcinoma metastasis, epithelial-mesenchymal transition and cancer stem cell-like properties by inhibiting PI3K/AKT and WNT/β-catenin signaling activation.
Metformin Carbon Dots for Promoting Periodontal Bone Regeneration via Activation of ERK/AMPK Pathway.
PARP inhibitors promote stromal fibroblast activation by enhancing CCL5 autocrine signaling in ovarian cancer.
CircC16orf62 promotes hepatocellular carcinoma progression through the miR-138-5p/PTK2/AKT axis.
SARS-CoV-2 exacerbates proinflammatory responses in myeloid cells through C-type lectin receptors and Tweety family member 2.
SNP rs10420324 in the AMPA receptor auxiliary subunit TARP γ-8 regulates the susceptibility to antisocial personality disorder.
Chronic exposure to PFO4DA and PFO5DoDA, two perfluoroalkyl ether carboxylic acids (PFECAs), suppresses hepatic stress signals and disturbs glucose and lipid metabolism in male mice.
The functional characterization of phosphorylation of tristetraprolin at C-terminal NOT1-binding domain.
Design, synthesis, and neuroprotective effects of novel hybrid compounds containing edaravone analogue and 3-n-butylphthalide ring-opened derivatives.
Protective effects of prucalopride in MPTP-induced Parkinson's disease mice: Neurochemistry, motor function and gut barrier.
Matrine suppresses cell growth of diffuse large B-cell lymphoma via inhibiting CaMKIIγ/c-Myc/CDK6 signaling pathway.
YTHDF1 promotes hepatocellular carcinoma progression via activating PI3K/AKT/mTOR signaling pathway and inducing epithelial-mesenchymal transition.
Formin-like protein 2 promotes cell proliferation by a p27-related mechanism in human breast cancer cells.
Self-stabilizing regulation of deubiquitinating enzymes in an enzymatic activity-dependent manner.
The lipid-lowering drug fenofibrate combined with si-HOTAIR can effectively inhibit the proliferation of gliomas.
IL-37b alleviates endothelial cell apoptosis and inflammation in Kawasaki disease through IL-1R8 pathway.
The CTNNBIP1-CLSTN1 fusion transcript regulates human neocortical development.
HCP5, as the sponge of miR-1291, facilitates AML cell proliferation and restrains apoptosis via increasing PIK3R5 expression.
Trim21-mediated HIF-1α degradation attenuates aerobic glycolysis to inhibit renal cancer tumorigenesis and metastasis.
A network-based analysis and experimental validation of traditional Chinese medicine Yuanhu Zhitong Formula in treating neuropathic pain.
Ginsenoside Rh2 alleviates ulcerative colitis by regulating the STAT3/miR-214 signaling pathway.
Smek1 deficiency exacerbates experimental autoimmune encephalomyelitis by activating proinflammatory microglia and suppressing the IDO1-AhR pathway.
The Anti-Tumor Effect and Underlying Apoptotic Mechanism of Ginsenoside Rk1 and Rg5 in Human Liver Cancer Cells.
An integrative transcriptome study reveals Ddit4/Redd1 as a key regulator of cancer cachexia in rodent models.
NOL4L, a novel nuclear protein, promotes cell proliferation and metastasis by enhancing the PI3K/AKT pathway in ovarian cancer.
Circ3823 contributes to growth, metastasis and angiogenesis of colorectal cancer: involvement of miR-30c-5p/TCF7 axis.
A knockout cell library of GPI biosynthetic genes for functional studies of GPI-anchored proteins.
Ferryl Hemoglobin and Heme Induce A(1)-Microglobulin in Hemorrhaged Atherosclerotic Lesions with Inhibitory Function against Hemoglobin and Lipid Oxidation.
Tissue- and stage-specific landscape of the mouse translatome.
m(6)A RNA hypermethylation-induced BACE2 boosts intracellular calcium release and accelerates tumorigenesis of ocular melanoma.
TROAP regulates cell cycle and promotes tumor progression through Wnt/β-Catenin signaling pathway in glioma cells.
Mesenchymal stem cells ameliorate silica-induced pulmonary fibrosis by inhibition of inflammation and epithelial-mesenchymal transition.
Effects of WNT1 c.110 T>C and c.505G>T mutations on osteoblast differentiation via the WNT1/β-catenin signaling pathway.
A protocol for in vivo analysis of liver tumorigenesis in mice using sleeping beauty transposon system.
Hypoxic postconditioning promotes mitophagy against transient global cerebral ischemia via PINK1/Parkin-induced mitochondrial ubiquitination in adult rats.
Long noncoding RNA AFAP1-AS1 promotes tumor progression and invasion by regulating the miR-2110/Sp1 axis in triple-negative breast cancer.
Arginine methylation of METTL14 promotes RNA N(6)-methyladenosine modification and endoderm differentiation of mouse embryonic stem cells.
ALS/FTD mutations in UBQLN2 are linked to mitochondrial dysfunction through loss-of-function in mitochondrial protein import.
Single-cell RNA-seq reveals fibroblast heterogeneity and increased mesenchymal fibroblasts in human fibrotic skin diseases.
Cold Atmospheric Plasma Promotes Killing of Staphylococcus aureus by Macrophages.
OGA is associated with deglycosylation of NONO and the KU complex during DNA damage repair.
Exosomal SNHG16 secreted by CSCs promotes glioma development via TLR7.
UBQLN2-HSP70 axis reduces poly-Gly-Ala aggregates and alleviates behavioral defects in the C9ORF72 animal model.
MicroRNA-139 inhibits pancreatic-cancer carcinogenesis by suppressing RalB via the Ral/RAC/PI3K pathway.
Nimodipine inhibits intestinal and aortic smooth muscle contraction by regulating Ca(2+)-activated Cl(-) channels.
Mechanosensitive expression of lamellipodin promotes intracellular stiffness, cyclin expression and cell proliferation.
Prrx1 promotes stemness and angiogenesis via activating TGF-β/smad pathway and upregulating proangiogenic factors in glioma.
G-protein-coupled receptor GPR17 inhibits glioma development by increasing polycomb repressive complex 1-mediated ROS production.
RNF220-mediated ubiquitination promotes aggresomal accumulation and autophagic degradation of cytoplasmic Gli via HDAC6.
Vincristine attenuates cardiac fibrosis through the inhibition of NLRP3 inflammasome activation.
Selenium Status in Diet Affects Acetaminophen-Induced Hepatotoxicity via Interruption of Redox Environment.
STAT1 epigenetically regulates LCP2 and TNFAIP2 by recruiting EP300 to contribute to the pathogenesis of inflammatory bowel disease.
Reducing lipofuscin accumulation and cardiomyocytic senescence of aging heart by enhancing autophagy.
Tumors exploit FTO-mediated regulation of glycolytic metabolism to evade immune surveillance.
A kinome screen reveals that Nemo-like kinase is a key suppressor of hepatic gluconeogenesis.
VEGF/Src signaling mediated pleural barrier damage and increased permeability contributes to subpleural pulmonary fibrosis.
High uric acid induces liver fat accumulation via ROS/JNK/AP-1 signaling.
THAP11 down-regulation may contribute to cardio-protective effects of sevoflurane anesthesia: Evidence from clinical and molecular evidence.
Nicotinamide mononucleotide attenuates isoproterenol-induced cardiac fibrosis by regulating oxidative stress and Smad3 acetylation.
MIR29A Impedes Metastatic Behaviors in Hepatocellular Carcinoma via Targeting LOX, LOXL2, and VEGFA.
Inducible ATP1B1 Upregulates Antiviral Innate Immune Responses by the Ubiquitination of TRAF3 and TRAF6.
Microglial IL-10 and β-endorphin expression mediates gabapentinoids antineuropathic pain.
Expression of Cntn1 is regulated by stress and associated with anxiety and depression phenotypes.
GCH1 induces immunosuppression through metabolic reprogramming and IDO1 upregulation in triple-negative breast cancer.
MiR-519d-5p modulates the sensitivity of breast cancer to chemotherapy by forming a negative feedback loop with RELA.
LXRβ is involved in the control of platelet production from megakaryocytes.
Wireless Localized Electrical Stimulation Generated by an Ultrasound-Driven Piezoelectric Discharge Regulates Proinflammatory Macrophage Polarization.
Multiregional profiling of the brain transmembrane proteome uncovers novel regulators of depression.
Sulforaphane Balances Ca(2+) Homeostasis Injured by Excessive Fat via Mitochondria-Associated Membrane (MAM).
Enhancing immunogenicity of HPV16 E(7) DNA vaccine by conjugating codon-optimized GM-CSF to HPV16 E(7) DNA.
The LncRNA RP11-279C4.1 Enhances the Malignant Behaviour of Glioma Cells and Glioma Stem-Like Cells by Regulating the miR-1273g-3p/CBX3 Axis.
Generation of a TLR2 homozygous knockout human embryonic stem cell line WAe001-A-64 using CRISPR/Cas9 editing.
Neutrophil extracellular traps promote gastric cancer metastasis by inducing epithelial‑mesenchymal transition.
Selenium triggers Nrf2-AMPK crosstalk to alleviate cadmium-induced autophagy in rabbit cerebrum.
EZH2 regulates expression of FOXC1 by mediating H3K27me3 in breast cancers.
Exosomes are involved in total body irradiation-induced intestinal injury in mice.
YB1 regulates miR-205/200b-ZEB1 axis by inhibiting microRNA maturation in hepatocellular carcinoma.
A multifaceted role of progranulin in regulating amyloid-beta dynamics and responses.
MiR-706 alleviates white matter injury via downregulating PKCα/MST1/NF-κB pathway after subarachnoid hemorrhage in mice.
Direct control of store-operated calcium channels by ultrafast laser.
Aflatoxin B1 inhibited autophagy flux by inducing lysosomal alkalinization in HepG2 cells.
MicroRNA-215-5p inhibits the proliferation of keratinocytes and alleviates psoriasis-like inflammation by negatively regulating DYRK1A and its downstream signalling pathways.
Mechanistic insights into mitochondrial tRNA(Ala) 3'-end metabolism deficiency.
MACF1 promotes osteoblast differentiation by sequestering repressors in cytoplasm.
Overexpression of SERPINA3 promotes tumor invasion and migration, epithelial-mesenchymal-transition in triple-negative breast cancer cells.
Human umbilical cord mesenchymal stem cell-derived exosomes inhibit migration and invasion of breast cancer cells via miR-21-5p/ZNF367 pathway.
Caspase-1 inhibits IFN-β production via cleavage of cGAS during M. bovis infection.
METTL16 promotes cell proliferation by up-regulating cyclin D1 expression in gastric cancer.
Gankyrin activates the hedgehog signalling to drive metastasis in osteosarcoma.
Different roles of BAG3 in cardiac physiological hypertrophy and pathological remodeling.
Cancer cell-intrinsic STING is associated with CD8 + T-cell infiltration and might serve as a potential immunotherapeutic target in hepatocellular carcinoma.
Effects of TRIM59 on RAW264.7 macrophage gene expression and function.
Mechanism of validamycin A inhibiting DON biosynthesis and synergizing with DMI fungicides against Fusarium graminearum.
Effect of the interference with DRP1 expression on the biological characteristics of glioma stem cells.
C1orf61 promotes hepatocellular carcinoma metastasis and increases the therapeutic response to sorafenib.
Metabolomic profiling of single enlarged lysosomes.
Activation of Ca(2+)/Calmodulin-Dependent Protein Kinase II (CaMKII) with Lidocaine Provokes Pyroptosis of Glioblastoma Cells.
SNX17 protects the heart from doxorubicin-induced cardiotoxicity by modulating LMOD2 degradation.
Dihydrotanshinone I inhibits aortic valve interstitial cell calcification via the SMAD1/5/8/NF-κB/ERK pathway.
Fucoxanthin rescues dexamethasone induced C2C12 myotubes atrophy.
Tacrolimus inhibits oral carcinogenesis through cell cycle control.
Choline attenuates heat stress-induced oxidative injury and apoptosis in bovine mammary epithelial cells by modulating PERK/Nrf-2 signaling pathway.
Brevilin A inhibits NLRP3 inflammasome activation in vivo and in vitro by acting on the upstream of NLRP3-induced ASC oligomerization.
Upregulation of estrogen receptor beta protein but not mRNA predicts poor prognosis and may be associated with enhanced translation in non-small cell lung cancer: a systematic review and meta-analysis.
ASAP1 regulates the uptake of Mycobacterium tuberculosis H37Ra in THP1-derived macrophages by remodeling actin cytoskeleton.
Calycosin attenuates pulmonary fibrosis by the epithelial-mesenchymal transition repression upon inhibiting the AKT/GSK3β/β-catenin signaling pathway.
KIN17 promotes tumor metastasis by activating EMT signaling in luminal-A breast cancer.
C188-9 reduces TGF-β1-induced fibroblast activation and alleviates ISO-induced cardiac fibrosis in mice.
Protective effects of VMY-2-95 on corticosterone-induced injuries in mice and cellular models.
miRNA-194 predicts favorable prognosis in gastric cancer and inhibits gastric cancer cell growth by targeting CCND1.
Murine Ifit3 restricts the replication of Rabies virus both in vitro and in vivo.
Tubeimoside I improves endothelial function in sepsis via activation of SIRT3.
The Sonic Hedgehog signaling pathway regulates autophagy and migration in ovarian cancer.
Discovery of β-Carboline Derivatives as a Highly Potent Cardioprotectant against Myocardial Ischemia-Reperfusion Injury.
YBX1 is required for maintaining myeloid leukemia cell survival by regulating BCL2 stability in an m6A-dependent manner.
Intestinal Klebsiella pneumoniae infection enhances susceptibility to epileptic seizure which can be reduced by microglia activation.
Inhibition of xCT suppresses the efficacy of anti-PD-1/L1 melanoma treatment through exosomal PD-L1-induced macrophage M2 polarization.
The cardiac translational landscape reveals that micropeptides are new players involved in cardiomyocyte hypertrophy.
Prognostic signature composed of transcription factors accurately predicts the prognosis of gastric cancer patients.
Participation of Mind Bomb-2 in Sevoflurane Anesthesia Induces Cognitive Impairment in Aged Mice via Modulating Ferroptosis.
USP19 promotes hypoxia-induced mitochondrial division via FUNDC1 at ER-mitochondria contact sites.
Identification and optimization of 3-bromo-N'-(4-hydroxybenzylidene)-4-methylbenzohydrazide derivatives as mTOR inhibitors that induce autophagic cell death and apoptosis in triple-negative breast cancer.
The intrinsic role and mechanism of tumor expressed-CD38 on lung adenocarcinoma progression.
A flavonoid-rich Smilax china L. extract prevents obesity by upregulating the adiponectin-receptor/AMPK signalling pathway and modulating the gut microbiota in mice.
Lnc-STYK1-2 regulates bladder cancer cell proliferation, migration, and invasion by targeting miR-146b-5p expression and AKT/STAT3/NF-kB signaling.
Integrated bioinformatics analysis revealed the regulation of angiogenesis by tumor cells in hepatocellular carcinoma.
Anti-anemia drug FG4592 retards the AKI-to-CKD transition by improving vascular regeneration and antioxidative capability.
Glycoursodeoxycholic acid ameliorates diet-induced metabolic disorders with inhibiting endoplasmic reticulum stress.
Propofol differentially induces unconsciousness and respiratory depression through distinct interactions between GABAA receptor and GABAergic neuron in corresponding nuclei.
TBN improves motor function and prolongs survival in a TDP-43M337V mouse model of ALS.
Pterostilbene alleviates pulmonary fibrosis by regulating ASIC2.
Analysis of the Internal Hypoxic Environment in Solid Tumor Tissue Using a Folding Paper System.
The anti-dysenteric drug fraxetin enhances anti-tumor efficacy of gemcitabine and suppresses pancreatic cancer development by antagonizing STAT3 activation.
MINDY1 promotes bladder cancer progression by stabilizing YAP.
Serum exosomes from young rats improve the reduced osteogenic differentiation of BMSCs in aged rats with osteoporosis after fatigue loading in vivo.
Tree Shrew Cells Transduced with Human CD4 and CCR5 Support Early Steps of HIV-1 Replication, but Viral Infectivity Is Restricted by APOBEC3.
Nuclear iASPP determines cell fate by selectively inhibiting either p53 or NF-κB.
GNAI2 Promotes Proliferation and Decreases Apoptosis in Rabbit Melanocytes.
Behavioral effects of early-life exposure to perfluorooctanoic acid might synthetically link to multiple aspects of dopaminergic neuron development and dopamine functions in zebrafish larvae.
Phenethylamine in chlorella alleviates high-fat diet-induced mouse liver damage by regulating generation of methylglyoxal.
A CREB1-miR-181a-5p loop regulates the pathophysiologic features of bone marrow stromal cells in fibrous dysplasia of bone.
Autophagy-related circRNA evaluation reveals hsa_circ_0001747 as a potential favorable prognostic factor for biochemical recurrence in patients with prostate cancer.
Role of MCP-1 and IL-8 in viral anterior uveitis, and contractility and fibrogenic activity of trabecular meshwork cells.
Epitranscriptomic editing of the RNA N6-methyladenosine modification by dCasRx conjugated methyltransferase and demethylase.
Lactate secreted by PKM2 upregulation promotes Galectin-9-mediated immunosuppression via inhibiting NF-κB pathway in HNSCC.
SARS-CoV-2 Restructures the Host Chromatin Architecture.
Comparable radiation sensitivity in p53 wild-type and p53 deficient tumor cells associated with different cell death modalities.
A mesenchymal-like subpopulation in non-neuroendocrine SCLC contributes to metastasis.
TGF-β1-mediated exosomal lnc-MMP2-2 increases blood-brain barrier permeability via the miRNA-1207-5p/EPB41L5 axis to promote non-small cell lung cancer brain metastasis.
Inactivation of the tumor suppressor p53 by long noncoding RNA RMRP.
Variations in Env at amino acids 328 and 330 affect HIV-1 replicative fitness and entry inhibitor sensitivity.
The molecular basis of coupling between poly(A)-tail length and translational efficiency.
MALDI-MS-based biomarker analysis of extracellular vesicles from human lung carcinoma cells.
MARCH6 promotes hepatocellular carcinoma development through up-regulation of ATF2.
Erlotinib protests against LPS-induced parthanatos through inhibiting macrophage surface TLR4 expression.
BMI1 activates P-glycoprotein via transcription repression of miR-3682-3p and enhances chemoresistance of bladder cancer cell.
Role of NLR family pyrin domain-containing 3 inflammasome in the activation of pancreatic stellate cells.
Asiatic acid attenuates diabetic retinopathy through TLR4/MyD88/NF-κB p65 mediated modulation of microglia polarization.
Chlamydia trachomatis Pgp3 protein regulates oxidative stress via activation of the Nrf2/NQO1 signal pathway.
The mechanisms of action of WeiChang'An Pill (WCAP) treat diarrhoea-predominant irritable bowel syndrome (IBS-D) using network pharmacology approach and in vivo studies.
Proteomics analysis in the kidney of mice following oral feeding Realgar.
Identification and validation of an immune-related prognostic signature and key gene in papillary thyroid carcinoma.
Nonstructural Protein NSs Hampers Cellular Antiviral Response through LSm14A during Severe Fever with Thrombocytopenia Syndrome Virus Infection.
Role of IL-6-IL-27 Complex in Host Antiviral Immune Response.
Protective effects and mechanisms of high-dose vitamin C on sepsis-associated cognitive impairment in rats.
Ubiquitin-specific protease 15 contributes to gastric cancer progression by regulating the Wnt/β-catenin signaling pathway.
LncRNA PCGEM1 induces proliferation and migration in non-small cell lung cancer cells through modulating the miR-590-3p/SOX11 axis.
Cyclophilin A Inhibits Human Respiratory Syncytial Virus (RSV) Replication by Binding to RSV-N through Its PPIase Activity.
S-Allylmercapto-N-acetylcysteine ameliorates elastase-induced chronic obstructive pulmonary disease in mice via regulating autophagy.
YTHDF2 facilitates UBXN1 mRNA decay by recognizing METTL3-mediated m(6)A modification to activate NF-κB and promote the malignant progression of glioma.
Repression of the AURKA-CXCL5 axis induces autophagic cell death and promotes radiosensitivity in non-small-cell lung cancer.
Epitranscriptomic addition of m(6)A regulates HIV-1 RNA stability and alternative splicing.
p55PIK deficiency and its NH(2)-terminal derivative inhibit inflammation and emphysema in COPD mouse model.
GALNT2 promotes cell proliferation, migration, and invasion by activating the Notch/Hes1-PTEN-PI3K/Akt signaling pathway in lung adenocarcinoma.
IL37 overexpression inhibits autophagy and apoptosis induced by hepatic ischemia reperfusion injury via modulating AMPK/mTOR/ULLK1 signalling pathways.
Seneca Valley Virus 3C Protease Induces Pyroptosis by Directly Cleaving Porcine Gasdermin D.
SUMO proteases SENP3 and SENP5 spatiotemporally regulate the kinase activity of Aurora A.
Long noncoding RNA BS-DRL1 modulates the DNA damage response and genome stability by interacting with HMGB1 in neurons.
Toll-like receptor-2 gene knockout results in neurobehavioral dysfunctions and multiple brain structural and functional abnormalities in mice.
Hepatocyte growth factor mediates a novel form of hepatic stem/progenitor cell-induced tolerance in a rat xenogeneic liver rejection model.
MicroRNA-124-3p affects myogenic differentiation of adipose-derived stem cells by targeting Caveolin-1 during pelvic floor dysfunction in Sprague Dawley rats.
Repressing PDCD4 activates JNK/ABCG2 pathway to induce chemoresistance to fluorouracil in colorectal cancer cells.
RNA-binding protein QKI suppresses breast cancer via RASA1/MAPK signaling pathway.
The Beneficial Role of Sunitinib in Tumor Immune Surveillance by Regulating Tumor PD-L1.
Preventive effect of dioscin against monosodium urate-mediated gouty arthritis through inhibiting inflammasome NLRP3 and TLR4/NF-κB signaling pathway activation: an in vivo and in vitro study.
ETV5 Regulates Hepatic Fatty Acid Metabolism Through PPAR Signaling Pathway.
TBC1D3 promotes neural progenitor proliferation by suppressing the histone methyltransferase G9a.
MicroRNA-489-3p Represses Hepatic Stellate Cells Activation by Negatively Regulating the JAG1/Notch3 Signaling Pathway.
FIGNL1 promotes non‑small cell lung cancer cell proliferation.
Parthenolide inhibits the tumor characteristics of renal cell carcinoma.
Dysfunction of Shh signaling activates autophagy to inhibit trophoblast motility in recurrent miscarriage.
DNA methylation of Hugl-2 is a prognostic biomarker in kidney renal clear cell carcinoma.
Prostaglandin E2 serves a dual role in regulating the migration of dendritic cells.
Avasimibe exerts anticancer effects on human glioblastoma cells via inducing cell apoptosis and cell cycle arrest.
UHRF1 Knockdown Attenuates Cell Growth, Migration, and Invasion in Cutaneous Squamous Cell Carcinoma.
Flavonoid compound breviscapine suppresses human osteosarcoma Saos-2 progression property and induces apoptosis by regulating mitochondria-dependent pathway.
Nucleolin regulates 14-3-3ζ mRNA and promotes cofilin phosphorylation to induce tunneling nanotube formation.
Mefunidone ameliorates diabetic kidney disease in STZ and db/db mice.
Rapid antidepressant-like effect of Fructus Aurantii depends on cAMP-response element binding protein/Brain-derived neurotrophic facto by mediating synaptic transmission.
Effects of Y Box Binding Protein-1 in Progression and Prognosis of Cholangiocarcinoma.
Long noncoding RNA LINC00460 promotes the progression of cervical cancer via regulation of the miR-361-3p/Gli1 axis.
Long noncoding RNA TSLNC8 enhances pancreatic cancer aggressiveness by regulating CTNNB1 expression via association with HuR.
Hemizygous deletion of Tbk1 worsens neuromuscular junction pathology in TDP-43(G298S) transgenic mice.
MiR-19b-3p accelerates bone loss after spinal cord injury by suppressing osteogenesis via regulating PTEN/Akt/mTOR signalling.
Maltol prevents the progression of osteoarthritis by targeting PI3K/Akt/NF-κB pathway: In vitro and in vivo studies.
Mixed-lineage leukaemia 1 contributes to endometrial stromal cells progesterone responsiveness during decidualization.
Blocking VRK2 suppresses pulmonary adenocarcinoma progression via ERK1/2/AKT signal pathway by targeting miR-145-5p.
Treatment of keloids through Runx2 siRNA‑induced inhibition of the PI3K/AKT signaling pathway.
Protection against Dextran Sulfate Sodium-Induced Ulcerative Colitis in Mice by Neferine, A Natural Product from Nelumbo nucifera Gaertn.
Effect of HMGB1 on monocyte immune function in respiratory syncytial virus bronchiolitis.
miR-155-5p regulates macrophage M1 polarization and apoptosis in the synovial fluid of patients with knee osteoarthritis.
Contribution of DNA methyltransferases to spared nerve injury induced depression partially through epigenetically repressing Bdnf in hippocampus: Reversal by ketamine.
Suppressed nuclear envelope proteins activate autophagy of vascular smooth muscle cells during cyclic stretch application.
Inhibition of proliferation-linked signaling cascades with atractylenolide I reduces myofibroblastic phenotype and renal fibrosis.
P-glycoprotein deficiency enhances metabolic activation of and platelet response to clopidogrel through marked up-regulation of Cyp3a11 in mice: Direct evidence for the interplay between P-glycoprotein and Cyp3a.
NCBP3/SNHG6 inhibits GBX2 transcription in a histone modification manner to facilitate the malignant biological behaviour of glioma cells.
Targeted inhibition of Rev-erb-α/β limits ferroptosis to ameliorate folic acid-induced acute kidney injury.
Inhibition of ferroptosis by up-regulating Nrf2 delayed the progression of diabetic nephropathy.
The inhibition of colorectal cancer growth by the natural product macrocarpal I.
HSF1 functions as a key defender against palmitic acid-induced ferroptosis in cardiomyocytes.
Exosome-mediated delivery of antisense oligonucleotides targeting α-synuclein ameliorates the pathology in a mouse model of Parkinson's disease.
Elevated ZBTB7A expression in the tumor invasive front correlates with more tumor budding formation in gastric adenocarcinoma.
A SMOC2 variant inhibits BMP signaling by competitively binding to BMPR1B and causes growth plate defects.
Melatonin increases the chemosensitivity of diffuse large B-cell lymphoma cells to epirubicin by inhibiting P-glycoprotein expression via the NF-κB pathway.
miRNA-146a-5p mitigates stress-induced premature senescence of D-galactose-induced primary thymic stromal cells.
CLDN10 associated with immune infiltration is a novel prognostic biomarker for clear cell renal cell carcinoma.
Hyperglycemia-reduced NAD(+) biosynthesis impairs corneal epithelial wound healing in diabetic mice.
NNT-induced tumor cell "slimming" reverses the pro-carcinogenesis effect of HIF2a in tumors.
Disrupted glucose homeostasis and skeletal-muscle-specific glucose uptake in an exocyst knockout mouse model.
Determining the quantitative relationship between glycolysis and GAPDH in cancer cells exhibiting the Warburg effect.
Salvianolic acid B blocks hepatic stellate cell activation via FGF19/FGFR4 signaling.
Melatonin ameliorates hepatic steatosis by inhibiting NLRP3 inflammasome in db/db mice.
Valproic acid Suppresses Breast Cancer Cell Growth Through Triggering Pyruvate Kinase M2 Isoform Mediated Warburg Effect.
Electroacupuncture Attenuates Morphine Tolerance in Rats with Bone Cancer Pain by Inhibiting PI3K/Akt/JNK1/2 Signaling Pathway in the Spinal Dorsal Horn.
Heparan sulfate 3-O-sulfotransferase 4 is genetically associated with herpes zoster and enhances varicella-zoster virus-mediated fusogenic activity.
Thermoresponsive GenisteinNLC-dexamethasone-moxifloxacin multi drug delivery system in lens capsule bag to prevent complications after cataract surgery.
Effects of ER-resident and secreted AGR2 on cell proliferation, migration, invasion, and survival in PANC-1 pancreatic cancer cells.
Intraperitoneal injection of Desferal® alleviated the age-related bone loss and senescence of bone marrow stromal cells in rats.
Indoleamine 2,3-dioxygenase 1 limits hepatic inflammatory cells recruitment and promotes bile duct ligation-induced liver fibrosis.
Rabies virus matrix protein targets host actin cytoskeleton: a protein-protein interaction analysis.
Lnc-GAN1 expression is associated with good survival and suppresses tumor progression by sponging mir-26a-5p to activate PTEN signaling in non-small cell lung cancer.
MCCC2 promotes HCC development by supporting leucine oncogenic function.
Environmental noise stress disturbs commensal microbiota homeostasis and induces oxi-inflammmation and AD-like neuropathology through epithelial barrier disruption in the EOAD mouse model.
miR-142 downregulation alleviates rat PTSD-like behaviors, reduces the level of inflammatory cytokine expression and apoptosis in hippocampus, and upregulates the expression of fragile X mental retardation protein.
Leptin Receptor (LEPR) promotes proliferation, migration, and invasion and inhibits apoptosis in hepatocellular carcinoma by regulating ANXA7.
Tumor genotype dictates radiosensitization after Atm deletion in primary brainstem glioma models.
Improvement of obesity-associated disorders by a small-molecule drug targeting mitochondria of adipose tissue macrophages.
Interplay of opposing fate choices stalls oncogenic growth in murine skin epithelium.
Neuroprotective effects of SOX5 against ischemic stroke by regulating VEGF/PI3K/AKT pathway.
Discovery and proteomics analysis of effective compounds in Valeriana jatamansi jones for the treatment of anxiety.
Angiogenesis is promoted by exosomal DPP4 derived from 5-fluorouracil-resistant colon cancer cells.
LncRNA H19-Derived miR-675-5p Accelerates the Invasion of Extravillous Trophoblast Cells by Inhibiting GATA2 and Subsequently Activating Matrix Metalloproteinases.
Connective tissue growth factor promotes chemotaxis of preosteoblasts through integrin α5 and Ras during tensile force-induced intramembranous osteogenesis.
Echinatin effectively protects against NLRP3 inflammasome-driven diseases by targeting HSP90.
Vitamin D alleviates liver fibrosis by inhibiting histidine-rich calcium binding protein (HRC).
Immunophenotype of Gastric Tumors Unveils a Pleiotropic Role of Regulatory T Cells in Tumor Development.
Long-read transcriptome sequencing reveals abundant promoter diversity in distinct molecular subtypes of gastric cancer.
Discovery of a Functional Covalent Ligand Targeting an Intrinsically Disordered Cysteine within MYC.
Human umbilical cord mesenchymal stem cell-derived exosomal miR-146a-5p reduces microglial-mediated neuroinflammation via suppression of the IRAK1/TRAF6 signaling pathway after ischemic stroke.
SERCA2a ameliorates cardiomyocyte T-tubule remodeling via the calpain/JPH2 pathway to improve cardiac function in myocardial ischemia/reperfusion mice.
Identification of Cleavage Sites Proteolytically Processed by NS2B-NS3 Protease in Polyprotein of Japanese Encephalitis Virus.
An Autism-Associated Mutation Impairs Neuroligin-4 Glycosylation and Enhances Excitatory Synaptic Transmission in Human Neurons.
Notoginsenoside R1 attenuates breast cancer progression by targeting CCND2 and YBX3.
Adipose-derived stromal cells improve functional recovery after spinal cord injury through TGF-β1/Smad3/PLOD2 pathway activation.
The mitochondrial protein ERAL1 suppresses RNA virus infection by facilitating RIG-I-like receptor signaling.
Development of DNA Vaccine Targeting E6 and E7 Proteins of Human Papillomavirus 16 (HPV16) and HPV18 for Immunotherapy in Combination with Recombinant Vaccinia Boost and PD-1 Antibody.
Hsa_circ_0007456 regulates the natural killer cell-mediated cytotoxicity toward hepatocellular carcinoma via the miR-6852-3p/ICAM-1 axis.
Human RECQL5 promotes metastasis and resistance to cisplatin in non-small cell lung cancer.
MicroRNA-150 affects endoplasmic reticulum stress via MALAT1-miR-150 axis-mediated NF-κB pathway in LPS-challenged HUVECs and septic mice.
Discovery of a novel small-molecule inhibitor of Fam20C that induces apoptosis and inhibits migration in triple negative breast cancer.
Atractylodis macrocephalae polysaccharides protect against DSS-induced intestinal injury through a novel lncRNA ITSN1-OT1.
Circ_0001438 participates in the pathogenesis of preeclampsia via the circ_0001438/miR-942/NLRP3 regulatory network.
Single cell transcriptomic analysis of human pluripotent stem cell chondrogenesis.
Functional constipation induces bladder overactivity associated with upregulations of Htr2 and Trpv2 pathways.
Genome-wide Screens Identify Lineage- and Tumor-Specific Genes Modulating MHC-I- and MHC-II-Restricted Immunosurveillance of Human Lymphomas.
miR-199b-5p enhances the proliferation of medullary thymic epithelial cells via regulating Wnt signaling by targeting Fzd6.
The DDX39B/FUT3/TGFβR-I axis promotes tumor metastasis and EMT in colorectal cancer.
Cellular and molecular landscape of mammalian sinoatrial node revealed by single-cell RNA sequencing.
Transcription elongation factor A-like 7, regulated by miR-758-3p inhibits the progression of melanoma through decreasing the expression levels of c-Myc and AKT1.
Mtu1 defects are correlated with reduced osteogenic differentiation.
Knockdown of CENPF inhibits the progression of lung adenocarcinoma mediated by ERβ2/5 pathway.
Tetrachlorobenzoquinone exhibits immunotoxicity by inducing neutrophil extracellular traps through a mechanism involving ROS-JNK-NOX2 positive feedback loop.
Canstatin represses glioma growth by inhibiting formation of VM-like structures.
SQSTM1/ p62 oligomerization contributes to Aβ-induced inhibition of Nrf2 signaling.
Kiaa0101 serves as a prognostic marker and promotes invasion by regulating p38/snail1 pathway in glioma.
Eldecalcitol induces apoptosis and autophagy in human osteosarcoma MG-63 cells by accumulating ROS to suppress the PI3K/Akt/mTOR signaling pathway.
Gastrin-17 induces gastric cancer cell epithelial-mesenchymal transition via the Wnt/β-catenin signaling pathway.
RNA-binding protein HuR suppresses senescence through Atg7 mediated autophagy activation in diabetic intervertebral disc degeneration.
Kcnh2 mediates FAK/AKT-FOXO3A pathway to attenuate sepsis-induced cardiac dysfunction.
lncRNA NEAT1 ameliorates LPS‑induced inflammation in MG63 cells by activating autophagy and suppressing the NLRP3 inflammasome.
lncRNA FOXP4‑AS1 predicts poor prognosis and accelerates the progression of mantle cell lymphoma through the miR‑423‑5p/NACC1 pathway.
Circular RNA circNFATC3 acts as a miR-9-5p sponge to promote cervical cancer development by upregulating SDC2.
OPA1 haploinsufficiency due to a novel splicing variant resulting in mitochondrial dysfunction without mitochondrial DNA depletion.
CRISPR/Cas9 screening identifies a kinetochore-microtubule dependent mechanism for Aurora-A inhibitor resistance in breast cancer.
PRMT1 enhances oncogenic arginine methylation of NONO in colorectal cancer.
miR-23a-3p regulated by LncRNA SNHG5 suppresses the chondrogenic differentiation of human adipose-derived stem cells via targeting SOX6/SOX5.
MicroRNA-936/ERBB4/Akt axis exhibits anticancer properties of gastric cancer through inhibition of cell proliferation, migration, and invasion.
The Kv1.3 ion channel acts as a host factor restricting viral entry.
Rosmarinic acid exerts an antagonistic effect on nonalcoholic fatty liver disease by regulating the YAP1/TAZ-PPARγ/PGC-1α signaling pathway.
COPII mitigates ER stress by promoting formation of ER whorls.
UBE2O targets Mxi1 for ubiquitination and degradation to promote lung cancer progression and radioresistance.
TDP-43 aggregation induced by oxidative stress causes global mitochondrial imbalance in ALS.
The interaction between lipocalin 2 and dipyridine ketone hydrazone dithiocarbamte may influence respective function in proliferation and metastasis-related gene expressions in HepG2 cell.
M2 macrophage-derived G-CSF promotes trophoblasts EMT, invasion and migration via activating PI3K/Akt/Erk1/2 pathway to mediate normal pregnancy.
LINC01116 promotes proliferation and migration of endometrial stromal cells by targeting FOXP1 via sponging miR-9-5p in endometriosis.
FoxM1 promotes Wnt/β-catenin pathway activation and renal fibrosis via transcriptionally regulating multi-Wnts expressions.
AGGF1 inhibits the expression of inflammatory mediators and promotes angiogenesis in dental pulp cells.
Ptk2b deletion improves mice folliculogenesis and fecundity via inhibiting follicle loss mediated by Erk pathway.
Molecular mechanism underlying miR‑130b‑Sp1 transcriptional regulation in LPS‑induced upregulation of MUC5AC in the bile duct epithelium.
Knockdown of long non‑coding RNA ANRIL inhibits the proliferation and promotes the apoptosis of Burkitt lymphoma cells through the TGF‑β1 signaling pathway.
Matrix metalloproteinase 3 regulates angiotensin II‑induced myocardial fibrosis cell viability, migration and apoptosis.
Benzidine promotes the stemness of bladder cancer stem cells via activation of the Sonic hedgehog pathway.
Crosstalk between phosphorylation and ubiquitination is involved in high salt-induced WNK4 expression.
Dysregulation of phosphoproteins in hepatocellular carcinoma revealed via quantitative analysis of the phosphoproteome.
Inhibition of autophagy aggravates molybdenum-induced mitochondrial dysfunction by aggravating oxidative stress in duck renal tubular epithelial cells.
Clinical and molecular characterization of thirty Chinese patients with congenital lipoid adrenal hyperplasia.
Viral RNA-binding ability conferred by SUMOylation at PB1 K612 of influenza A virus is essential for viral pathogenesis and transmission.
Predicting therapeutic drugs for hepatocellular carcinoma based on tissue-specific pathways.
Cryptotanshinone specifically suppresses NLRP3 inflammasome activation and protects against inflammasome-mediated diseases.
Genistein inhibits radiation-induced invasion and migration of glioblastoma cells by blocking the DNA-PKcs/Akt2/Rac1 signaling pathway.
20-HETE downregulates Na/K-ATPase α1 expression via the ubiquitination pathway.
Loss of STAT5A promotes glucose metabolism and tumor growth through miRNA-23a-AKT signaling in hepatocellular carcinoma.
Compound heterozygous mutation of the ASXL3 gene causes autosomal recessive congenital heart disease.
Whole-Transcriptome Profiling of Human Heart Tissues Reveals the Potential Novel Players and Regulatory Networks in Different Cardiomyopathy Subtypes of Heart Failure.
Knockdown of dual oxidase 1 suppresses activin A-induced fibrosis in cardiomyocytes via the reactive oxygen species-dependent pyroptotic pathway.
MicroRNA-520c-3p targeting of RelA/p65 suppresses atherosclerotic plaque formation.
MiR-146a mediates TLR-4 signaling pathway to affect myocardial fibrosis in rat constrictive pericarditis model.
RabGEF1 functions as an oncogene in U251 glioblastoma cells and is involved in regulating AKT and Erk pathways.
A loss-of-function mutation p.T256M in NDRG4 is implicated in the pathogenesis of pulmonary atresia with ventricular septal defect (PA/VSD) and tetralogy of Fallot (TOF).
Layer-by-layer self-assembly polyelectrolytes loaded with cyclic adenosine monophosphate enhances the osteo/odontogenic differentiation of stem cells from apical papilla.
HOXA10 mediates epithelial-mesenchymal transition to promote gastric cancer metastasis partly via modulation of TGFB2/Smad/METTL3 signaling axis.
FKBP10 promotes proliferation of glioma cells via activating AKT-CREB-PCNA axis.
DDB2 regulates DNA replication through PCNA-independent degradation of CDT2.
miR-374 improves cerebral ischemia reperfusion injury by targeting Wnt5a.
Adipocyte-specific deletion of zinc finger protein 407 results in lipodystrophy and insulin resistance in mice.
Humanin regulates oxidative stress in the ovaries of polycystic ovary syndrome patients via the Keap1/Nrf2 pathway.
RTN1-C mediates cerebral ischemia/reperfusion injury via modulating autophagy.
Long non-coding RNA CCDC183-AS1 acts AS a miR-589-5p sponge to promote the progression of hepatocellular carcinoma through regulating SKP1 expression.
miR-224-5p Contained in Urinary Extracellular Vesicles Regulates PD-L1 Expression by Inhibiting Cyclin D1 in Renal Cell Carcinoma Cells.
Angiopoietin 2 stimulates trophoblast invasion via a mechanism associated with JNK signaling.
Prpf31 is essential for the survival and differentiation of retinal progenitor cells by modulating alternative splicing.
Cancer-associated fibroblast-derived SDF-1 induces epithelial-mesenchymal transition of lung adenocarcinoma via CXCR4/β-catenin/PPARδ signalling.
UBE3C promotes proliferation and inhibits apoptosis by activating the β-catenin signaling via degradation of AXIN1 in gastric cancer.
Inhibition of the Otub1/c-Maf axis by the herbal acevaltrate induces myeloma cell apoptosis.
Radiotherapy and immunotherapy converge on elimination of tumor-promoting erythroid progenitor cells through adaptive immunity.
p53 induces ARTS to promote mitochondrial apoptosis.
Pterostilbene inhibits gallbladder cancer progression by suppressing the PI3K/Akt pathway.
Genome-wide analysis of pseudogenes reveals HBBP1's human-specific essentiality in erythropoiesis and implication in β-thalassemia.
Abnormal level of paxillin in cervical cancer cells is involved in tumor progression and invasion.
Nuclear factor Y participates in alcoholic liver disease by activating SREBP1 expression in mice.
SFPQ regulates the accumulation of RNA foci and dipeptide repeat proteins from the expanded repeat mutation in C9orf72.
GBP5 drives malignancy of glioblastoma via the Src/ERK1/2/MMP3 pathway.
LncRNA CDKN2B-AS1 stabilized by IGF2BP3 drives the malignancy of renal clear cell carcinoma through epigenetically activating NUF2 transcription.
E3 ligase Nedd4l promotes antiviral innate immunity by catalyzing K29-linked cysteine ubiquitination of TRAF3.
LncRNA HOXA-AS3 promotes gastric cancer progression by regulating miR-29a-3p/LTβR and activating NF-κB signaling.
Critical roles of sphingosine kinase 1 in the regulation of neuroinflammation and neuronal injury after spinal cord injury.
Direct activation of endothelial cells by SARS-CoV-2 nucleocapsid protein is blocked by Simvastatin.
Hepatic connective tissue growth factor expression and regulation differ between non-steatotic and non-alcoholic steatotic livers from brain-dead donor.
CREB1 protects against the renal injury in a rat model of kidney stone disease and calcium oxalate monohydrate crystals-induced injury in NRK-52E cells.
Down-regulation of A(3)AR signaling by IL-6-induced GRK2 activation contributes to Th17 cell differentiation.
Nobiletin downregulates the SKP2-p21/p27-CDK2 axis to inhibit tumor progression and shows synergistic effects with palbociclib on renal cell carcinoma.
RECQL4 regulates DNA damage response and redox homeostasis in esophageal cancer.
Gentisic acid prevents diet-induced obesity in mice by accelerating the thermogenesis of brown adipose tissue.
Uric acid inhibits HMGB1-TLR4-NF-κB signaling to alleviate oxygen-glucose deprivation/reoxygenation injury of microglia.
A novel regulatory loop miR-101/ANXA2/EGR1 mediates malignant characteristics of liver cancer stem cells.
DUOX2 promotes the progression of colorectal cancer cells by regulating the AKT pathway and interacting with RPL3.
Icariside I specifically facilitates ATP or nigericin-induced NLRP3 inflammasome activation and causes idiosyncratic hepatotoxicity.
The DNA methylation-regulated MCTP1 activates the drug-resistance of esophageal cancer cells.
Formononetin attenuates atopic dermatitis by upregulating A20 expression via activation of G protein-coupled estrogen receptor.
Gas6 or Mer deficiency ameliorates silica-induced autophagosomes accumulation in mice lung.
Berberine regulates macrophage polarization through IL-4-STAT6 signaling pathway in Helicobacter pylori-induced chronic atrophic gastritis.
The PDZ Domain Protein SYNJ2BP Regulates GRK-Dependent Sst2A Phosphorylation and Downstream MAPK Signaling.
ATM inhibition enhances cancer immunotherapy by promoting mtDNA leakage and cGAS/STING activation.
The S1PR1 agonist SEW2871 promotes the survival of skin flap.
Red ginseng has stronger anti-aging effects compared to ginseng possibly due to its regulation of oxidative stress and the gut microbiota.
LncRNA CAIF suppresses LPS-induced inflammation and apoptosis of cardiomyocytes through regulating miR-16 demethylation.
Long non-coding RNA AC122108.1 promotes lung adenocarcinoma brain metastasis and progression through the Wnt/β-catenin pathway by directly binding to aldolase A.
Mechanism of neutrophil extracellular traps generation and their role in trophoblasts apoptosis in gestational diabetes mellitus.
Ginsenoside Rb1 alleviates liver injury induced by 3-chloro-1,2-propanediol by stimulating autophagic flux.
Maternal Benzophenone Exposure Impairs Hippocampus Development and Cognitive Function in Mouse Offspring.
Targeting conserved N-glycosylation blocks SARS-CoV-2 variant infection in vitro.
MiR-192-5p suppresses M1 macrophage polarization via epiregulin (EREG) downregulation in gouty arthritis.
Molecular Mechanism of the ATF6α/S1P/S2P Signaling Pathway in Hippocampal Neuronal Apoptosis in SPS Rats.
Trametinib enhances ATRA-induced differentiation in AML cells.
Increased expression of PSME2 is associated with clear cell renal cell carcinoma invasion by regulating BNIP3‑mediated autophagy.
Wei Chang An pill regulates gastrointestinal motility in a bidirectional manner.
Nucleoporin 37 promotes the cell proliferation, migration, and invasion of gastric cancer through activating the PI3K/AKT/mTOR signaling pathway.
Hypoxia-inducible factor-1α promotes proliferation of airway smooth muscle cells through miRNA-103-mediated signaling pathway under hypoxia.
CoCrMo-Nanoparticles induced peri-implant osteolysis by promoting osteoblast ferroptosis via regulating Nrf2-ARE signalling pathway.
Bone marrow macrophage-derived exosomal miR-143-5p contributes to insulin resistance in hepatocytes by repressing MKP5.
Splicing factor proline and glutamine rich intron retention, reduced expression and aggregate formation are pathological features of amyotrophic lateral sclerosis.
Role of miR-145-5p/ CD40 in the inflammation and apoptosis of HUVECs induced by PM(2.5).
Endoplasmic reticulum stress pathway mediates T-2 toxin-induced chondrocyte apoptosis.
YTHDF1 promotes the proliferation, migration, and invasion of prostate cancer cells by regulating TRIM44.
Activation of SK3 channel plays a pivotal role in modulation of trigeminal neuralgia.
Endothelial METTL3 (Methyltransferase-Like 3) Inhibits Fibrinolysis by Promoting PAI-1 (Plasminogen Activator Inhibitor-1) Expression Through Enhancing Jun Proto-Oncogene N6-Methyladenosine Modification.
Exposure interval to ambient fine particulate matter (PM2.5) collected in Southwest China induced pulmonary damage through the Janus tyrosine protein kinase-2/signal transducer and activator of transcription-3 signaling pathway both in vivo and in vitro.
Lobetyolin inhibits the proliferation of breast cancer cells via ASCT2 down-regulation-induced apoptosis.
AK003290 Protects Myocardial Cells Against Apoptosis and Promotes Cardiac Function Recovery Via miR-539-3p/ErbB4 Axis in Ischemic-Reperfusion Injury.
Insulin-like growth factor reduced against decabromodiphenyl ether-209-induced neurodevelopmental toxicity in vivo and in vitro.
Non-canonical activation of the ER stress sensor ATF6 by Legionella pneumophila effectors.
Expression of CD47 in the pancreatic β-cells of people with recent-onset type 1 diabetes varies according to disease endotype.
Caspase-8 Regulates the Antimyeloma Activity of Bortezomib and Lenalidomide.
Two Inhibitors Against the 3C-Like Proteases of Swine Coronavirus and Feline Coronavirus.
Angiomotin-like 1 plays a tumor-promoting role in glioma by enhancing the activation of YAP1 signaling.
Amelioratory effect of neoandrographolide on myocardial ischemic-reperfusion injury by its anti-inflammatory and anti-apoptotic activities.
Dual inhibition of EGFR and IL-6-STAT3 signalling by miR-146b: a potential targeted therapy for epithelial ovarian cancer.
CircPrkcsh, a circular RNA, contributes to the polarization of microglia towards the M1 phenotype induced by spinal cord injury and acts via the JNK/p38 MAPK pathway.
BAIAP2L2 promotes the proliferation, migration and invasion of osteosarcoma associated with the Wnt/β-catenin pathway.
Mdivi-1 alleviates atopic dermatitis through the inhibition of NLRP3 inflammasome.
Mitophagy mediates metabolic reprogramming of induced pluripotent stem cells undergoing endothelial differentiation.
Blockade of JAK2 signaling produces immunomodulatory effect to preserve pancreatic homeostasis in severe acute pancreatitis.
Protective effect of Idelalisib on carbon tetrachloride-induced liver fibrosis via microRNA-124-3P/phosphatidylinositol-3-hydroxykinase signalling pathway.
MET inhibition enhances PARP inhibitor efficacy in castration-resistant prostate cancer by suppressing the ATM/ATR and PI3K/AKT pathways.
Huoxin pill prevents acute myocardial ischaemia injury via inhibition of Wnt/β-catenin signaling.
Depletion of m(6) A reader protein YTHDC1 induces dilated cardiomyopathy by abnormal splicing of Titin.
hsa‑miR‑429 targets CBX8 to promote cell apoptosis in diffuse large B‑cell lymphoma.
Peroxisome proliferator‑activated receptor β/δ regulates cerebral vasospasm after subarachnoid hemorrhage via modulating vascular smooth muscle cells phenotypic conversion.
Huoxue Qianyang Qutan recipe attenuates Ang II-induced cardiomyocyte hypertrophy by regulating reactive oxygen species production.
MicroRNA-602 prevents the development of inflammatory bowel diseases in a microbiota-dependent manner.
Hsa-miR-335 enhances cell migration and invasion in lung adenocarcinoma through targeting Copine-1.
Diterpenoid alkaloids from Delphinium forrestii var. viride and their anti-inflammation activity.
MicroRNA-455-5p/CPEB1 pathway mediates Aβ-related learning and memory deficits in a mouse model of Alzheimer's disease.
Resveratrol and its derivative pterostilbene attenuate oxidative stress-induced intestinal injury by improving mitochondrial redox homeostasis and function via SIRT1 signaling.
Isosteroidal alkaloids from Fritillaria hupehensis Hsiao et K.C.Hsia: Synthesis and biological evaluation of alkaloid derivatives as potential cytotoxic agents.
c-Jun N-terminal kinase (JNK) signaling contributes to cystic burden in polycystic kidney disease.
CUL3 (cullin 3)-mediated ubiquitination and degradation of BECN1 (beclin 1) inhibit autophagy and promote tumor progression.
Ferritinophagy is involved in the zinc oxide nanoparticles-induced ferroptosis of vascular endothelial cells.
Long noncoding RNA (lncRNA) EIF3J-DT induces chemoresistance of gastric cancer via autophagy activation.
Lanthanum chloride induces autophagy in primary cultured rat cortical neurons through Akt/mTOR and AMPK/mTOR signaling pathways.
Pentagalloylglucose reduces AGE-induced inflammation by activating Nrf2/HO-1 and inhibiting the JAK2/STAT3 pathway in mesangial cells.
Pyruvate kinase M2 (PKM2) interacts with activating transcription factor 2 (ATF2) to bridge glycolysis and pyroptosis in microglia.
LncRNA RP1-86C11.7 exacerbates the glioma progression and oncogenicity by hsa-miR-144-3p/TFRC signaling.
Ablation of USP21 in skeletal muscle promotes oxidative fibre phenotype, inhibiting obesity and type 2 diabetes.
Linc00467 promotion of gastric cancer development by directly regulating miR-7-5p expression and downstream epidermal growth factor receptor.
Hsa_circ_0030586 promotes epithelial-mesenchymal transition in prostate cancer via PI3K-AKT signaling.
MicroRNA-98-5p modulates cervical cancer progression via controlling PI3K/AKT pathway.
Ubiquitin-associated protein 2 like (UBAP2L) enhances growth and metastasis of gastric cancer cells.
Orosomucoid 1 promotes epirubicin resistance in breast cancer by upregulating the expression of matrix metalloproteinases 2 and 9.
Solid lipid nanoparticle delivery of rhynchophylline enhanced the efficiency of allergic asthma treatment via the upregulation of suppressor of cytokine signaling 1 by repressing the p38 signaling pathway.
MiR-1224-5p attenuates polycystic ovary syndrome through inhibiting NOD-like receptor protein 3 inflammasome activation via targeting Forkhead box O 1.
Long non-coding RNA LOC107985656 represses the proliferation of hepatocellular carcinoma cells through activation of the tumor-suppressive Hippo pathway.
Circular RNA circCRKL inhibits the proliferation of acute myeloid leukemia cells via the miR-196a-5p/miR-196b-5p/p27 axis.
Impact of hepatocyte-specific deletion of staphylococcal nuclease and tudor domain containing 1 (SND1) on liver insulin resistance and acute liver failure of mice.
Dynamic Dissection of Dynein and Kinesin-1 Cooperatively Mediated Intercellular Transport of Porcine Epidemic Diarrhea Coronavirus along Microtubule Using Single Virus Tracking.
α-Actinin1 promotes tumorigenesis and epithelial-mesenchymal transition of gastric cancer via the AKT/GSK3β/β-Catenin pathway.
T-box transcription factor TBX1, targeted by microRNA-6727-5p, inhibits cell growth and enhances cisplatin chemosensitivity of cervical cancer cells through AKT and MAPK pathways.
The tumor-suppressive effects of alpha-ketoglutarate-dependent dioxygenase FTO via N6-methyladenosine RNA methylation on bladder cancer patients.
Activation of NLR family, domain of pyrin containing 3 inflammasome by nitrous oxide through thioredoxin-interacting protein to induce nerve cell injury.
Danshensu alleviates bleomycin-induced pulmonary fibrosis by inhibiting lung fibroblast-to-myofibroblast transition via the MEK/ERK signaling pathway.
Site-specific SUMOylation of viral polymerase processivity factor: a way of localizingtoND10 subnuclear domains for restricted and self-controlled reproduction of herpesvirus.
MicroRNA-146b-3p regulates the dysfunction of vascular smooth muscle cells via repressing phosphoinositide-3 kinase catalytic subunit gamma.
Long non-coding RNA (lncRNA) PGM5P4-AS1 inhibits lung cancer progression by up-regulating leucine zipper tumor suppressor (LZTS3) through sponging microRNA miR-1275.
Catalpol ameliorates psoriasis-like phenotypes via SIRT1 mediated suppression of NF-κB and MAPKs signaling pathways.
A novel circular RNA (hsa_circ_0059930)-mediated miRNA-mRNA axis in the lipopolysaccharide-induced acute lung injury model of MRC-5 cells.
Integrin β3 overexpression contributes to podocyte injury through inhibiting RhoA/YAP signaling pathway.
Long intergenic noncoding RNA00265 promotes proliferation of gastric cancer via the microRNA-144-3p/Chromobox 4 axis.
Tyrosine kinase nonreceptor 1 (TNK1) knockdown ameliorates hemorrhage shock-induced kidney injury via inhibiting macrophage M1 polarization.
Spatiotemporal regulation of JAZ4 expression and splicing contribute to ethylene- and auxin-mediated responses in Arabidopsis roots.
Veratric acid alleviates liver ischemia/reperfusion injury by activating the Nrf2 signaling pathway.
The impact of tobacco exposure on tumor microenvironment and prognosis in lung adenocarcinoma by integrative analysis of multi-omics data.
Sulfiredoxin-1 protects retinal ganglion cells from high glucose-induced oxidative stress and inflammatory injury by potentiating Nrf2 signaling via the Akt/GSK-3β pathway.
Topoisomerase 2 inhibitor etoposide promotes interleukin-10 production in LPS-induced macrophages via upregulating transcription factor Maf and activating PI3K/Akt pathway.
Aggregation-Induced Emission (AIE) Nanoparticles-Assisted NIR-II Fluorescence Imaging-Guided Diagnosis and Surgery for Inflammatory Bowel Disease (IBD).
Pak2 reduction induces a failure of early embryonic development in mice.
Artesunate treatment ameliorates ultraviolet irradiation-driven skin photoaging via increasing β-catenin expression.
NuMA regulates mitotic spindle assembly, structural dynamics and function via phase separation.
HOPX Plays a Critical Role in Antiretroviral Drugs Induced Epigenetic Modification and Cardiac Hypertrophy.
Uncovering a conserved vulnerability site in SARS-CoV-2 by a human antibody.
miR-140-3p enhanced the osteo/odontogenic differentiation of DPSCs via inhibiting KMT5B under hypoxia condition.
RND3 attenuates oxidative stress and vascular remodeling in spontaneously hypertensive rat via inhibiting ROCK1 signaling.
(20S) Ginsenoside Rh2 Exerts Its Anti-Tumor Effect by Disrupting the HSP90A-Cdc37 System in Human Liver Cancer Cells.
Glucocorticoid receptor regulates PD-L1 and MHC-I in pancreatic cancer cells to promote immune evasion and immunotherapy resistance.
Berberrubine attenuates potassium oxonate- and hypoxanthine-induced hyperuricemia by regulating urate transporters and JAK2/STAT3 signaling pathway.
Ultrasound triggered topical delivery of Bmp7 mRNA for white fat browning induction via engineered smart exosomes.
Efficient induction of proximity-dependent labelling by biotin feeding in BMAL1-BioID knock-in mice.
Hepatoprotective effect of genistein against dimethylnitrosamine-induced liver fibrosis in rats by regulating macrophage functional properties and inhibiting the JAK2/STAT3/SOCS3 signaling pathway.
Initiation of oogenesis and meiosis in the fetal ovary depends on Dennd1a-mediated production of Wnt5a and retinoic acid from the somatic niches.
USP30-AS1 contributes to mitochondrial quality control in glioblastoma cells.
LRRC4 mediates the formation of circular RNA CD44 to inhibitGBM cell proliferation.
The RNA binding protein QKI5 suppresses ovarian cancer via downregulating transcriptional coactivator TAZ.
Integration of transcriptome and proteome profiles in placenta accreta reveals trophoblast over-migration as the underlying pathogenesis.
Loss-of-function missense variant of AKAP4 induced male infertility through reduced interaction with QRICH2 during sperm flagella development.
TdIF1-LSD1 Axis Regulates Epithelial-Mesenchymal Transition and Metastasis via Histone Demethylation of E-Cadherin Promoter in Lung Cancer.
MyD88 Mediates Colitis- and RANKL-Induced Microfold Cell Differentiation.
SARS-CoV-2 Variants of Concern Infect the Respiratory Tract and Induce Inflammatory Response in Wild-Type Laboratory Mice.
Rosmanol and Carnosol Synergistically Alleviate Rheumatoid Arthritis through Inhibiting TLR4/NF-κB/MAPK Pathway.
6-Thioguanine Inhibits Herpes Simplex Virus 1 Infection of Eyes.
Pan-cancer analysis of N4-acetylcytidine adaptor THUMPD1 as a predictor for prognosis and immunotherapy.
miR-378d suppresses malignant phenotype of ESCC cells through AKT signaling.
MIIP inhibits clear cell renal cell carcinoma proliferation and angiogenesis via negative modulation of the HIF-2α-CYR61 axis.
Heat stress affects fetal brain and intestinal function associated with the alterations of placental barrier in late pregnant mouse.
Responses of JNK signaling pathway to the toxic dinoflagellate Prorocentrum lima in the mussel Perna viridis.
WTIP upregulates FOXO3a and induces apoptosis through PUMA in acute myeloid leukemia.
USP3 promotes gastric cancer progression and metastasis by deubiquitination-dependent COL9A3/COL6A5 stabilisation.
Identification of key genes as predictive biomarkers for osteosarcoma metastasis using translational bioinformatics.
A machine learning pipeline revealing heterogeneous responses to drug perturbations on vascular smooth muscle cell spheroid morphology and formation.
Anti-tumor effect of polysaccharide from Pleurotus ostreatus on H22 mouse Hepatoma ascites in-vivo and hepatocellular carcinoma in-vitro model.
CLN7 is an organellar chloride channel regulating lysosomal function.
Generation and analysis of innovative genomically humanized knockin SOD1, TARDBP (TDP-43), and FUS mouse models.
TCF4 and HuR mediated-METTL14 suppresses dissemination of colorectal cancer via N6-methyladenosine-dependent silencing of ARRDC4.
Antiviral Activities of Carbazole Derivatives against Porcine Epidemic Diarrhea Virus In Vitro.
WITHDRAWN: Role of microRNA-19b-3p on osteoporosis after experimental spinal cord injury in rats.
Lactoferrin Alleviates Acute Alcoholic Liver Injury by Improving Redox-Stress Response Capacity in Female C57BL/6J Mice.
A novel protoapigenone analog RY10-4 induces apoptosis of breast cancer cells by exacerbating mitochondrial Ca(2+) influx through mitochondrial calcium uniporter.
miR-126 regulates angiogenesis in myocardial ischemia by targeting HIF-1α.
Deficiency of the Ribosomal Protein uL5 Leads to Significant Rearrangements of the Transcriptional and Translational Landscapes in Mammalian Cells.
Synergistic anti-inflammatory activity of apigenin and curcumin co-encapsulated in caseins assessed with lipopolysaccharide-stimulated RAW 264.7 macrophages.
A Study on How Methionine Restriction Decreases the Body's Hepatic and Lipid Deposition in Rice Field Eel (Monopterus albus).
Effect of High Static Magnetic Fields on Biological Activities and Iron Metabolism in MLO-Y4 Osteocyte-like Cells.
Intermittent bolus feeding does not enhance protein synthesis, myonuclear accretion, or lean growth more than continuous feeding in a premature piglet model.
Role of the hippo signaling pathway in the extracellular matrix degradation of chondrocytes induced by fluoride exposure.
Cypermethrin triggers YY1-mediated testosterone biosynthesis suppression.
Klotho ameliorated cognitive deficits in a temporal lobe epilepsy rat model by inhibiting ferroptosis.
Nicaraven inhibits TNFα-induced endothelial activation and inflammation through suppression of NF-κB signaling pathway.
Adipose-derived stem cells (ADSCs) inhibit the expression of anti-apoptosis proteins through up-regulation of ATF4 on breast cancer cells.
Glaucocalyxin A induces apoptosis and autophagy in tongue squamous cell carcinoma cells by regulating ROS.
IL-10 ameliorates PM2.5-induced lung injury by activating the AMPK/SIRT1/PGC-1α pathway.
Hsa-miR-34a-5p reverses multidrug resistance in gastric cancer cells by targeting the 3'-UTR of SIRT1 and inhibiting its expression.
CircZNF208 enhances the sensitivity to X-rays instead of carbon-ions through the miR-7-5p /SNCA signal axis in non-small-cell lung cancer cells.
Heat shock protein 90 inhibitor ameliorates pancreatic fibrosis by degradation of transforming growth factor-β receptor.
The Regulation of Neutrophil Extracellular Trap-induced Tissue Damage by Human CD177.
6-Shogaol from ginger shows anti-tumor effect in cervical carcinoma via PI3K/Akt/mTOR pathway.
microRNA-4429-5p suppresses the malignant development of colon cancer by targeting matrix metalloproteinase 16.
ROBO2 hampers malignant biological behavior and predicts a better prognosis in pancreatic adenocarcinoma.
Effect of electro-acupuncture at ST 36 on maternal food restriction-induced lung phenotype in rat offspring.
Comparison of the biological and functional characteristics of mesenchymal stem cells from intrahepatic and identical bone marrow.
Establishment of two homozygous CRISPR interference (CRISPRi) knock-in human induced pluripotent stem cell (hiPSC) lines for titratable endogenous gene repression.
Base editing-mediated perturbation of endogenous PKM1/2 splicing facilitates isoform-specific functional analysis in vitro and in vivo.
Loss of microRNA-147 function alleviates synovial inflammation through ZNF148 in rheumatoid and experimental arthritis.
DJ-1 activates the noncanonical NF-κB pathway via interaction with Cezanne to inhibit the apoptosis and promote the proliferation of Ishikawa cells.
Long noncoding RNA uc003pxg.1 regulates endothelial cell proliferation and migration via miR‑25‑5p in coronary artery disease.
Increased AT(1) receptor expression mediates vasoconstriction leading to hypertension in Snx1(-/-) mice.
Downregulation of glucose-6-phosphatase expression contributes to fluoxetine-induced hepatic steatosis.
Chromium (VI) promotes EMT by regulating FLNA in BLCA.
Rearrangement of Actin Cytoskeleton by Zika Virus Infection Facilitates Blood-Testis Barrier Hyperpermeability.
Endothelial neuropilin-2 influences angiogenesis by regulating actin pattern development and α5-integrin-p-FAK complex recruitment to assembling adhesion sites.
Salidroside protects cardiac function in mice with diabetic cardiomyopathy via activation of mitochondrial biogenesis and SIRT3.
RNA m(6)A modification orchestrates a LINE-1-host interaction that facilitates retrotransposition and contributes to long gene vulnerability.
Inhibition of hepatitis E virus replication by zinc-finger antiviral Protein synergizes with IFN-β.
GINS2 promotes EMT in pancreatic cancer via specifically stimulating ERK/MAPK signaling.
Lys694Arg polymorphism leads to blunted responses to LPS by interfering TLR4 with recruitment of MyD88.
Genotype-dependent epigenetic regulation of DLGAP2 in alcohol use and dependence.
Helicobacter pylori induces gastric cancer via down-regulating miR-375 to inhibit dendritic cell maturation.
Vimentin rearrangement by phosphorylation is beneficial for porcine reproductive and respiratory syndrome virus replication in vitro.
EGCG synergizes the therapeutic effect of irinotecan through enhanced DNA damage in human colorectal cancer cells.
Ring finger protein 19A is overexpressed in non-small cell lung cancer and mediates p53 ubiquitin-degradation to promote cancer growth.
Propofol attenuates renal ischemia/reperfusion injury by regulating the MALAT1/miR-126-5p axis.
ASTE1 promotes shieldin-complex-mediated DNA repair by attenuating end resection.
Decreased TMEM40 expression is associated with malignant behavior of cutaneous squamous cell carcinoma and inhibits tumor progression.
Indoleamine 2,3-Dioxygenase 1 (IDO1) Promotes Cardiac Hypertrophy via a PI3K-AKT-mTOR-Dependent Mechanism.
A γ-adducin cleavage fragment induces neurite deficits and synaptic dysfunction in Alzheimer's disease.
Investigating the nature of active forces in tissues reveals how contractile cells can form extensile monolayers.
MiR-532-3p suppresses cell viability, migration and invasion of clear cell renal cell carcinoma through targeting TROAP.
Nitazoxanide impairs mitophagy flux through ROS-mediated mitophagy initiation and lysosomal dysfunction in bladder cancer.
Depletion of CIP2A inhibits the proliferation, migration, invasion and epithelial-mesenchymal transition of glioma cells.
The role of circTmeff-1 in incubation of context-induced morphine craving.
High-throughput screening and genome-wide analyses of 44 anticancer drugs in the 1000 Genomes cell lines reveals an association of the NQO1 gene with the response of multiple anticancer drugs.
PtdIns4P restriction by hydrolase SAC1 decides specific fusion of autophagosomes with lysosomes.
Classical swine fever virus infection suppresses claudin-1 expression to facilitate its replication in PK-15 cells.
Stabilization of Nrf2 leading to HO-1 activation protects against zinc oxide nanoparticles-induced endothelial cell death.
Bavachin enhances NLRP3 inflammasome activation induced by ATP or nigericin and causes idiosyncratic hepatotoxicity.
Expression of ISL1 and its partners in prostate cancer progression and neuroendocrine differentiation.
MD2 blockage prevents the migration and invasion of hepatocellular carcinoma cells via inhibition of the EGFR signaling pathway.
miR-744-5p suppresses tumor proliferation and metastasis by targeting transforming growth factor-beta 1 (TGF-β1) in hepatocellular carcinoma (HCC).
XPA serves as an autophagy and apoptosis inducer by suppressing hepatocellular carcinoma in a PI3K/Akt/mTOR dependent manner.
Vitamin D alleviates hypoxia/reoxygenation-induced injury of human trophoblast HTR-8 cells by activating autophagy.
Follicle-stimulating hormone worsens osteoarthritis by causing inflammation and chondrocyte dedifferentiation.
Renoprotective effects of levosimendan on acute kidney injury following cardiac arrest via anti-inflammation, anti-apoptosis, and ERK activation.
TRIM27 contributes to glomerular endothelial cell injury in lupus nephritis by mediating the FoxO1 signaling pathway.
Paraquat but not diquat induces TGF-β expression and thus activates calcium-NFAT axis for epithelial-mesenchymal transition.
AHR mediates the aflatoxin B1 toxicity associated with hepatocellular carcinoma.
Bcl-2-associated transcription factor 1 Ser290 phosphorylation mediates DNA damage response and regulates radiosensitivity in gastric cancer.
Autophagy-associated circular RNA hsa_circ_0007813 modulates human bladder cancer progression via hsa-miR-361-3p/IGF2R regulation.
MiR-133a-3p inhibits scar formation in scalded mice and suppresses the proliferation and migration of scar derived-fibroblasts by targeting connective tissue growth factor.
miR-145-5p attenuates inflammatory response and apoptosis in myocardial ischemia-reperfusion injury by inhibiting (NADPH) oxidase homolog 1.
Cofilin-1 promotes fibrocyte differentiation and contributes to pulmonary fibrosis.
Human CD4+ T-Cell Clone Expansion Leads to the Expression of the Cysteine Peptidase Inhibitor Cystatin F.
RNA-binding protein RBM47 stabilizes IFNAR1 mRNA to potentiate host antiviral activity.
PKCε controls the fusion of secretory vesicles in mast cells in a phosphatidic acid-dependent mode.
Methyltransferase-like 3 Modulates Severe Acute Respiratory Syndrome Coronavirus-2 RNA N6-Methyladenosine Modification and Replication.
Pericentromeric noncoding RNA changes DNA binding of CTCF and inflammatory gene expression in senescence and cancer.
UBE2T promotes autophagy via the p53/AMPK/mTOR signaling pathway in lung adenocarcinoma.
Enriched environment remedies cognitive dysfunctions and synaptic plasticity through NMDAR-Ca(2+)-Activin A circuit in chronic cerebral hypoperfusion rats.
AEG-1 silencing attenuates M2-polarization of glioma-associated microglia/macrophages and sensitizes glioma cells to temozolomide.
BGP-15 Inhibits Hyperglycemia-Aggravated VSMC Calcification Induced by High Phosphate.
Efficient intracellular delivery of proteins by a multifunctional chimaeric peptide in vitro and in vivo.
Autophagy Inhibition Plays a Protective Role in Ferroptosis Induced by Alcohol via the p62-Keap1-Nrf2 Pathway.
SESN2 protects against denervated muscle atrophy through unfolded protein response and mitophagy.
Biallelic SYNE2 Missense Mutations Leading to Nesprin-2 Giant Hypo-Expression Are Associated with Intellectual Disability and Autism.
Ten-eleven translocation 1 mediated-DNA hydroxymethylation is required for myelination and remyelination in the mouse brain.
Autophagic elimination of ribosomes during spermiogenesis provides energy for flagellar motility.
Helicobacter urease suppresses cytotoxic CD8+ T-cell responses through activating Myh9-dependent induction of PD-L1.
A single genetic locus controls both expression of DPEP1/CHMP1A and kidney disease development via ferroptosis.
Engineered basic fibroblast growth factor-overexpressing human umbilical cord-derived mesenchymal stem cells improve the proliferation and neuronal differentiation of endogenous neural stem cells and functional recovery of spinal cord injury by activating the PI3K-Akt-GSK-3β signaling pathway.
Sodium valproate increases activity of the sirtuin pathway resulting in beneficial effects for spinocerebellar ataxia-3 in vivo.
UHPLC-MS-based metabolomics and chemoinformatics study reveals the neuroprotective effect and chemical characteristic in Parkinson's disease mice after oral administration of Wen-Shen-Yang-Gan decoction.
Kaempferol attenuates diquat-induced oxidative damage and apoptosis in intestinal porcine epithelial cells.
Enhancer RNA m6A methylation facilitates transcriptional condensate formation and gene activation.
Repurposing of glycine transport inhibitors for the treatment of erythropoietic protoporphyria.
Gastrin exerts a protective effect against myocardial infarction via promoting angiogenesis.
Infection with Human Papillomavirus 18 Promotes Alkylating Agent-Induced Malignant Transformation in a Human Esophageal Cell Line.
Proof of Gene Doping in a Mouse Model with a Human Erythropoietin Gene Transferred Using an Adenoviral Vector.
Tubeimoside I protects against sepsis-induced cardiac dysfunction via SIRT3.
Silencing of RSPO1 mitigates obesity-related renal fibrosis in mice by deactivating Wnt/β-catenin pathway.
Long-term exposure to environmental level of phenanthrene causes adaptive immune response and fibrosis in mouse kidneys.
Itpr1 regulates the formation of anterior eye segment tissues derived from neural crest cells.
HPV16 E6 enhances the radiosensitivity in HPV-positive human head and neck squamous cell carcinoma by regulating the miR-27a-3p/SMG1 axis.
Targeted Ablation of Primary Cilia in Differentiated Dopaminergic Neurons Reduces Striatal Dopamine and Responsiveness to Metabolic Stress.
Loss of Smad4 promotes aggressive lung cancer metastasis by de-repression of PAK3 via miRNA regulation.
Serum exosomal pregnancy zone protein as a promising biomarker in inflammatory bowel disease.
Rab1A promotes cell proliferation and migration by upregulating Gli1 in colorectal cancer.
The Cell-Permeable Derivative of the Immunoregulatory Metabolite Itaconate, 4-Octyl Itaconate, Is Anti-Fibrotic in Systemic Sclerosis.
Humanin Alleviates Insulin Resistance in Polycystic Ovary Syndrome: A Human and Rat Model-Based Study.
TSH Activates Macrophage Inflammation by G13- and G15-dependent Pathways.
LncRNA ABCC6P1 promotes proliferation and migration of papillary thyroid cancer cells via Wnt/β-catenin signaling pathway.
ESM1 promotes triple-negative breast cancer cell proliferation through activating AKT/NF-κB/Cyclin D1 pathway.
hucMSCs transplantation promotes locomotor function recovery, reduces apoptosis and inhibits demyelination after SCI in rats.
Ginsenoside-Rg1 acts as an IDO1 inhibitor, protects against liver fibrosis via alleviating IDO1-mediated the inhibition of DCs maturation.
Bergenin inhibits bladder cancer progression via activating the PPARγ/PTEN/Akt signal pathway.
Arsenic-induced autophagy regulates apoptosis in AML-12 cells.
LncRNA XIST Promotes Migration and Invasion of Papillary Thyroid Cancer Cell by Modulating MiR-101-3p/CLDN1 Axis.
Mutant IDH1 Enhances Temozolomide Sensitivity via Regulation of the ATM/CHK2 Pathway in Glioma.
Morusin inhibits the growth of human colorectal cancer HCT116‑derived sphere‑forming cells via the inactivation of Akt pathway.
Mono-macrophage-Derived MANF Protects Against Lipopolysaccharide-Induced Acute Kidney Injury via Inhibiting Inflammation and Renal M1 Macrophages.
Aspergillus fumigatus-Stimulated Human Corneal Epithelial Cells Induce Pyroptosis of THP-1 Macrophages by Secreting TSLP.
Reduced intracellular chloride concentration impairs angiogenesis by inhibiting oxidative stress-mediated VEGFR2 activation.
MiR-32-5p knockdown inhibits epithelial to mesenchymal transition and renal fibrosis by targeting SMAD7 in diabetic nephropathy.
Cartilage endplate stem cells inhibit intervertebral disc degeneration by releasing exosomes to nucleus pulposus cells to activate Akt/autophagy.
LRP6 downregulation promotes cardiomyocyte proliferation and heart regeneration.
A chemical genetics approach to examine the functions of AAA proteins.
Programmed cell death 4 modulates lysosomal function by inhibiting TFEB translation.
Small molecule screening identified cepharanthine as an inhibitor of porcine reproductive and respiratory syndrome virus infection in vitro by suppressing integrins/ILK/RACK1/PKCα/NF-κB signalling axis.
Characterization of an endoplasmic reticulum stress-related signature to evaluate immune features and predict prognosis in glioma.
ARID1B/SUB1-activated lncRNA HOXA-AS2 drives the malignant behaviour of hepatoblastoma through regulation of HOXA3.
Helicobacter pylori inhibits autophagic flux and promotes its intracellular survival and colonization by down-regulating SIRT1.
Glucagon-like peptide 2 attenuates intestinal mucosal barrier injury through the MLCK/pMLC signaling pathway in a piglet model.
Ten-m/Odz3 regulates migration and differentiation of chondrogenic ATDC5 cells via RhoA-mediated actin reorganization.
Involvement of oxidative stress-induced annulus fibrosus cell and nucleus pulposus cell ferroptosis in intervertebral disc degeneration pathogenesis.
Novel role of CXCL14 in modulating STAR expression in luteinized granulosa cells: implication for progesterone synthesis in PCOS patients.
Melatonin exerts protective effects on diabetic retinopathy via inhibition of Wnt/β-catenin pathway as revealed by quantitative proteomics.
Depression-like behavior is associated with lower Per2 mRNA expression in the lateral habenula of rats.
MNK as a potential pharmacological target for suppressing LPS-induced acute lung injury in mice.
Harmine alleviates atherogenesis by inhibiting disturbed flow-mediated endothelial activation via protein tyrosine phosphatase PTPN14 and YAP.
A novel amphibian-derived peptide alleviated ultraviolet B-induced photodamage in mice.
Effects of miR-132-3p on progress and epithelial mesenchymal transition of non-small cell lung cancer via regulating KLF7.
POST1/C12ORF49 regulates the SREBP pathway by promoting site-1 protease maturation.
Transcription factor EB promotes rheumatoid arthritis of Sprague-Dawley rats via regulating autophagy.
DBA/1 mice display equivalent cardiac function to C57BL/6J mice.
A partial loss-of-function variant in GNRNR gene in a Chinese cohort with idiopathic hypogonadotropic hypogonadism.
PolyQ-expanded proteins impair cellular proteostasis of ataxin-3 through sequestering the co-chaperone HSJ1 into aggregates.
ATP6V0A1 encoding the a1-subunit of the V0 domain of vacuolar H(+)-ATPases is essential for brain development in humans and mice.
Therapeutic Effect of Endothelin-Converting Enzyme Inhibitor on Chronic Kidney Disease through the Inhibition of Endoplasmic Reticulum Stress and the NLRP3 Inflammasome.
Fangchinoline suppresses conjunctival melanoma by directly binding FUBP2 and inhibiting the homologous recombination pathway.
DOCK7 protects against replication stress by promoting RPA stability on chromatin.
MCPIP1-mediated NFIC alternative splicing inhibits proliferation of triple-negative breast cancer via cyclin D1-Rb-E2F1 axis.
Regulation of MRP4 Expression by circHIPK3 via Sponging miR-124-3p/miR-4524-5p in Hepatocellular Carcinoma.
ARID3A promotes the development of colorectal cancer by upregulating AURKA.
Anti-tumor activity of a novel proteasome inhibitor D395 against multiple myeloma and its lower cardiotoxicity compared with carfilzomib.
The role of E26 transformation-specific variant transcription factor 5 in colorectal cancer cell proliferation and cell cycle progression.
Tumor-derived exosomal circPSMA1 facilitates the tumorigenesis, metastasis, and migration in triple-negative breast cancer (TNBC) through miR-637/Akt1/β-catenin (cyclin D1) axis.
Multi-omics analysis to identify susceptibility genes for colorectal cancer.
Interaction of NEP with G Protein Pathway Suppressor 2 Facilitates Influenza A Virus Replication by Weakening the Inhibition of GPS2 to RNA Synthesis and Ribonucleoprotein Assembly.
Knockdown of the Ribosomal Protein eL38 in HEK293 Cells Changes the Translational Efficiency of Specific Genes.
ZIP8 mediates the extracellular matrix degradation of nucleus pulposus cells via NF-κB signaling pathway.
Abelson interactor 1 splice isoform-L plays an anti-oncogenic role in colorectal carcinoma through interactions with WAVE2 and full-length Abelson interactor 1.
Impaired 26S Proteasome Assembly Precedes Neuronal Loss in Mutant UBQLN2 Rats.
Generation of a Polyclonal Antibody against the Mouse Metal Transporter ZIP8.
Inhibition of Notch1 signaling reduces hepatocyte injury in nonalcoholic fatty liver disease via autophagy.
Role of Small Envelope Protein in Sustaining the Intracellular and Extracellular Levels of Hepatitis B Virus Large and Middle Envelope Proteins.
CircLIFR synergizes with MSH2 to attenuate chemoresistance via MutSα/ATM-p73 axis in bladder cancer.
RUNX1 promotes MAPK signaling to increase tumor progression and metastasis via OPN in head and neck cancer.
miR-324-3p reverses cisplatin resistance by inducing GPX4-mediated ferroptosis in lung adenocarcinoma cell line A549.
Crystal structures reveal a novel dimer of the RWD domain of human general control nonderepressible 2.
Promyelocytic leukemia protein promotes the phenotypic switch of smooth muscle cells in atherosclerotic plaques of human coronary arteries.
Effects of CMYA1 overexpression on cardiac structure and function in mice.
Dual effects of fibrinogen decoration on the tuning of silica nanoparticles-induced autophagic response: The implication of sedimentation and internalization.
Chemoproteomics-enabled discovery of covalent RNF114-based degraders that mimic natural product function.
Glaucocalyxin A induces cell cycle arrest and apoptosis via inhibiting NF-κB/p65 signaling pathway in melanoma cells.
Synthesis, characterization, and targeted chemotherapy of SCT200-linker-monomethyl auristatin E conjugates.
The biological function and clinical significance of STIL in osteosarcoma.
Loss of Mitochondrial Protease CLPP Activates Type I IFN Responses through the Mitochondrial DNA-cGAS-STING Signaling Axis.
AKR1B10 negatively regulates autophagy through reducing GAPDH upon glucose starvation in colon cancer.
KLF7/VPS35 axis contributes to hepatocellular carcinoma progression through CCDC85C-activated β-catenin pathway.
Cytoplasmic DNA sensing by KU complex in aged CD4(+) T cell potentiates T cell activation and aging-related autoimmune inflammation.
TDP-43 prevents endogenous RNAs from triggering a lethal RIG-I-dependent interferon response.
Changes in hepatic triglyceride content with the activation of ER stress and increased FGF21 secretion during pregnancy.
EpCAM promotes endosomal modulation of the cortical RhoA zone for epithelial organization.
TRIM39 deficiency inhibits tumor progression and autophagic flux in colorectal cancer via suppressing the activity of Rab7.
Reciprocal regulation of RIG-I and XRCC4 connects DNA repair with RIG-I immune signaling.
ADAMTS19 Suppresses Cell Migration and Invasion by Targeting S100A16 via the NF-κB Pathway in Human Gastric Cancer.
NET1 promotes HCC growth and metastasis in vitro and in vivo via activating the Akt signaling pathway.
p53-targeted lncRNA ST7-AS1 acts as a tumour suppressor by interacting with PTBP1 to suppress the Wnt/β-catenin signalling pathway in glioma.
Dcaf11 activates Zscan4-mediated alternative telomere lengthening in early embryos and embryonic stem cells.
Polychlorinated biphenyl quinone regulates MLKL phosphorylation that stimulates exosome biogenesis and secretion via a short negative feedback loop.
Design and screening of a novel neuropilin-1 targeted penetrating peptide for anti-angiogenic therapy in glioma.
RETRACTED: MicroRNA-376b-5p targets SOX7 to alleviate ischemic brain injury in a mouse model through activating Wnt/β-catenin signaling pathway.
RANK promotes colorectal cancer migration and invasion by activating the Ca(2+)-calcineurin/NFATC1-ACP5 axis.
Identification of Beilschmiedia tsangii Root Extract as a Liver Cancer Cell-Normal Keratinocyte Dual-Selective NRF2 Regulator.
Lycopene alleviates oxidative stress via the PI3K/Akt/Nrf2pathway in a cell model of Alzheimer's disease.
Conditioned medium from M2b macrophages modulates the proliferation, migration, and apoptosis of pulmonary artery smooth muscle cells by deregulating the PI3K/Akt/FoxO3a pathway.
Icariin protects against sodium azide-induced neurotoxicity by activating the PI3K/Akt/GSK-3β signaling pathway.
Glycyrrhizin suppresses epithelial-mesenchymal transition by inhibiting high-mobility group box1 via the TGF-β1/Smad2/3 pathway in lung epithelial cells.
miR-29a-3p directly targets Smad nuclear interacting protein 1 and inhibits the migration and proliferation of cervical cancer HeLa cells.
Examination of the Effect of a 50-Hz Electromagnetic Field at 500 μT on Parameters Related With the Cardiovascular System in Rats.
Mimicking the Organic and Inorganic Composition of Anabolic Bone Enhances Human Mesenchymal Stem Cell Osteoinduction and Scaffold Mechanical Properties.
Histone Deacetylases Inhibit the Snail2-Mediated EMT During Metastasis of Hepatocellular Carcinoma Cells.
RNA-Binding Protein HuR Suppresses Inflammation and Promotes Extracellular Matrix Homeostasis via NKRF in Intervertebral Disc Degeneration.
Knockdown of POSTN Inhibits Osteogenic Differentiation of Mesenchymal Stem Cells From Patients With Steroid-Induced Osteonecrosis.
Caspase-8 Inhibition Prevents the Cleavage and Degradation of E3 Ligase Substrate Receptor Cereblon and Potentiates Its Biological Function.
HDAC6 Regulates the Fusion of Autophagosome and Lysosome to Involve in Odontoblast Differentiation.
Transient Receptor Potential Channel 6 Knockout Ameliorates Kidney Fibrosis by Inhibition of Epithelial-Mesenchymal Transition.
Iron Overload Is Associated With Accelerated Progression of Osteoarthritis: The Role of DMT1 Mediated Iron Homeostasis.
miR-766-3p Targeting BCL9L Suppressed Tumorigenesis, Epithelial-Mesenchymal Transition, and Metastasis Through the β-Catenin Signaling Pathway in Osteosarcoma Cells.
Deficiency of LMP10 Attenuates Diet-Induced Atherosclerosis by Inhibiting Macrophage Polarization and Inflammation in Apolipoprotein E Deficient Mice.
p.His16Arg of STXBP1 (MUNC18-1) Associated With Syntaxin 3B Causes Autosomal Dominant Congenital Nystagmus.
EZH2-Inhibited MicroRNA-454-3p Promotes M2 Macrophage Polarization in Glioma.
Modulation of Increased mGluR1 Signaling by RGS8 Protects Purkinje Cells From Dendritic Reduction and Could Be a Common Mechanism in Diverse Forms of Spinocerebellar Ataxia.
MicroRNA-221/222 Mediates ADSC-Exosome-Induced Cardioprotection Against Ischemia/Reperfusion by Targeting PUMA and ETS-1.
Glycogen Phosphorylase B Is Regulated by miR101-3p and Promotes Hepatocellular Carcinoma Tumorigenesis.
Oct4 Regulates the Transition of Cancer Stem-Like Cells to Tumor Endothelial-Like Cells in Human Liver Cancer.
Overexpression of FAM46A, a Non-canonical Poly(A) Polymerase, Promotes Hemin-Induced Hemoglobinization in K562 Cells.
Siwei Jianbu decoction improves painful paclitaxel-induced peripheral neuropathy in mouse model by modulating the NF-κB and MAPK signaling pathways.
The Changes of Twist1 Pathway in Pulmonary Microvascular Permeability in a Newborn Rat Model of Hyperoxia-Induced Acute Lung Injury.
CDKN2a/p16 Antagonizes Hepatic Stellate Cell Activation and Liver Fibrosis by Modulating ROS Levels.
Crx Is Posttranscriptionally Regulated by Light Stimulation in Postnatal Rat Retina.
S-Adenosylmethionine Alleviates Amyloid-β-Induced Neural Injury by Enhancing Trans-Sulfuration Pathway Activity in Astrocytes.
Dendrobium nobile Lindl. Alkaloids Ameliorate Cognitive Dysfunction in Senescence Accelerated SAMP8 Mice by Decreasing Amyloid-β Aggregation and Enhancing Autophagy Activity.
Oxytocin Alleviates MPTP-Induced Neurotoxicity in Mice by Targeting MicroRNA-26a/Death-Associated Protein Kinase 1 Pathway.
miR-193a-3p Mediates Placenta Accreta Spectrum Development by Targeting EFNB2 via Epithelial-Mesenchymal Transition Pathway Under Decidua Defect Conditions.
DGCR8/miR-106 Axis Enhances Radiosensitivity of Head and Neck Squamous Cell Carcinomas by Downregulating RUNX3.
Identification of Transcriptional Variation in Aortic Remodeling Using a Murine Transverse Aortic Constriction (TAC) Model.
Dioscin Protects against Aβ1-42 Oligomers-Induced Neurotoxicity via the Function of SIRT3 and Autophagy.
Osthole: A Traditional Chinese Medicine for Ocular Anti-Angiogenic Therapy.
Electroacupuncture Improves Motor Symptoms of Parkinson's Disease and Promotes Neuronal Autophagy Activity in Mouse Brain.
Overexpression of MECP2 attenuates cigarette smoke extracts induced lung epithelial cell injury by promoting CYP1B1 methylation.
TRIB3 promotes hepatocellular carcinoma growth and predicts poor prognosis.
BMSC-derived leptin and IGFBP2 promote erlotinib resistance in lung adenocarcinoma cells through IGF-1R activation in hypoxic environment.
DLX6-AS1 promotes cell proliferation, migration and EMT of gastric cancer through FUS-regulated MAP4K1.
Effect of Wenshen-Yanggan Decoction on Movement Disorder and Substantia Nigra Dopaminergic Neurons in Mice with Chronic Parkinson's Disease.
Adrenal (Pro)renin Receptor Expression and Serum Soluble (Pro)renin Receptor Concentration in Primary Aldosteronism.
Autophagy Contributes to Host Immunity and Protection against Zika Virus Infection via Type I IFN Signaling.
Distinct Expression Patterns of Apoptosis and Autophagy-Associated Proteins and Genes during Postnatal Development of Spiral Ganglion Neurons in Rat.
Citron Rho-Interacting Serine/Threonine Kinase Promotes HIF1a-CypA Signaling and Growth of Human Pancreatic Adenocarcinoma.
Electroacupuncture Improved Chronic Cerebral Hypoperfusion-Induced Anxiety-Like Behavior and Memory Impairments in Spontaneously Hypertensive Rats by Downregulating the ACE/Ang II/AT1R Axis and Upregulating the ACE2/Ang-(1-7)/MasR Axis.
PBX3 Promotes Tumor Growth and Angiogenesis via Activation of AT1R/VEGFR2 Pathway in Papillary Thyroid Carcinoma.
AURKA Increase the Chemosensitivity of Colon Cancer Cells to Oxaliplatin by Inhibiting the TP53-Mediated DNA Damage Response Genes.
Jian-Pi-Yi-Shen Regulates EPO and Iron Recycling Protein Expressions in Anemic Rats with Chronic Kidney Disease: Accumulation of Hypoxia Inducible Factor-2α via ERK Signaling.
Exosomes from Bone Marrow Microenvironment-Derived Mesenchymal Stem Cells Affect CML Cells Growth and Promote Drug Resistance to Tyrosine Kinase Inhibitors.
Responsive Expression of MafF to β-Amyloid-Induced Oxidative Stress.
EA Ameliorated Depressive Behaviors in CUMS Rats and Was Related to Its Suppressing Autophagy in the Hippocampus.
Metformin Reduces the Senescence of Renal Tubular Epithelial Cells in Diabetic Nephropathy via the MBNL1/miR-130a-3p/STAT3 Pathway.
Fuzheng Huayu Recipe Prevented and Treated CCl4-Induced Mice Liver Fibrosis through Regulating Polarization and Chemotaxis of Intrahepatic Macrophages via CCL2 and CX3CL1.
Trained Innate Immunity by Repeated Low-Dose Lipopolysaccharide Injections Displays Long-Term Neuroprotective Effects.
Astaxanthin Protects Ochratoxin A-Induced Oxidative Stress and Apoptosis in the Heart via the Nrf2 Pathway.
Rhein Suppresses Neuroinflammation via Multiple Signaling Pathways in LPS-Stimulated BV2 Microglia Cells.
Adaptive Autophagy Offers Cardiorenal Protection in Rats with Acute Myocardial Infarction.
Anticancer Activity of Tetrandrine by Inducing Apoptosis in Human Breast Cancer Cell Line MDA-MB-231 In Vivo.
Tumor Necrosis Factor Receptor-Associated Protein 1 Protects against Mitochondrial Injury by Preventing High Glucose-Induced mPTP Opening in Diabetes.
Curcumin Inhibits Proliferation and Epithelial-Mesenchymal Transition in Lens Epithelial Cells through Multiple Pathways.
Mild Hypothermia Attenuates Hepatic Ischemia-Reperfusion Injury through Regulating the JAK2/STAT3-CPT1a-Dependent Fatty Acid β-Oxidation.
Plumbagin Enhances the Anticancer Efficacy of Cisplatin by Increasing Intracellular ROS in Human Tongue Squamous Cell Carcinoma.
NLRC3 Delays the Progression of AD in APP/PS1 Mice via Inhibiting PI3K Activation.
Protective Effect of Simplicillium sp. Ethyl Acetate Extract against High Glucose-Induced Oxidative Stress in HUVECs.
The Class III PI3K/Beclin-1 Autophagic Pathway Participates in the mmLDL-Induced Upregulation of ET(A) Receptor in Mouse Mesenteric Arteries.
Nei Endonuclease VIII-Like1 (NEIL1) Inhibits Apoptosis of Human Colorectal Cancer Cells.
Baicalin Ameliorates Cognitive Impairment and Protects Microglia from LPS-Induced Neuroinflammation via the SIRT1/HMGB1 Pathway.
Saponin from Periploca forrestii Schltr Mitigates Oxazolone-Induced Atopic Dermatitis via Modulating Macrophage Activation.
Roux-en-Y Gastric Bypass in Obese Diabetic Rats Promotes Autophagy to Improve Lipid Metabolism through mTOR/p70S6K Signaling Pathway.
Obesity-Induced Upregulation of ZBTB7A Promotes Lipid Accumulation through SREBP1.
Mining the Prognostic Value of HNRNPAB and Its Function in Breast Carcinoma.
Protective Role of Tangshen Formula on the Progression of Renal Damage in db/db Mice by TRPC6/Talin1 Pathway in Podocytes.
Tianma Gouteng Decoction Exerts Cardiovascular Protection by Upregulating OPG and TRAIL in Spontaneously Hypertensive Rats.
Quantitative Analysis of the Proteome and the Succinylome in the Thyroid Tissue of High-Fat Diet-Induced Hypothyroxinemia in Rats.
Prokineticin 2 (PK2) Rescues Cardiomyocytes from High Glucose/High Palmitic Acid-Induced Damage by Regulating the AKT/GSK3β Pathway In Vitro.
Anticancer Activity of Modified Tongyou Decoction on Eca109 Esophageal Cancer Cell Invasion and Metastasis through Regulation of the Epithelial-Mesenchymal Transition Mediated by the HIF-1α-Snail Axis.
GDF15 Repression Contributes to 5-Fluorouracil Resistance in Human Colon Cancer by Regulating Epithelial-Mesenchymal Transition and Apoptosis.
Ginsenoside Rg1 Alleviates Podocyte Injury Induced by Hyperlipidemia via Targeting the mTOR/NF-κB/NLRP3 Axis.
RRS1 Promotes Retinoblastoma Cell Proliferation and Invasion via Activating the AKT/mTOR Signaling Pathway.
Posttranslational Modification Defects in Fibroblast Growth Factor Receptor 1 as a Reason for Normosmic Isolated Hypogonadotropic Hypogonadism.
OSCC Exosomes Regulate miR-210-3p Targeting EFNA3 to Promote Oral Cancer Angiogenesis through the PI3K/AKT Pathway.
Lipin1 Is Involved in the Pathogenesis of Diabetic Encephalopathy through the PKD/Limk/Cofilin Signaling Pathway.
Emodin Alleviates Hydrogen Peroxide-Induced Inflammation and Oxidative Stress via Mitochondrial Dysfunction by Inhibiting the PI3K/mTOR/GSK3β Pathway in Neuroblastoma SH-SY5Y Cells.
Silencing of PRDX2 Inhibits the Proliferation and Invasion of Non-Small Cell Lung Cancer Cells.
Vagus Nerve Stimulation Alleviates Hepatic Ischemia and Reperfusion Injury by Regulating Glutathione Production and Transformation.
ADAM10 promotes cell growth, migration, and invasion in osteosarcoma via regulating E-cadherin/β-catenin signaling pathway and is regulated by miR-122-5p.
MYC-regulated lncRNA NEAT1 promotes B cell proliferation and lymphomagenesis via the miR-34b-5p-GLI1 pathway in diffuse large B-cell lymphoma.
Alantolactone inhibits cell autophagy and promotes apoptosis via AP2M1 in acute lymphoblastic leukemia.
A novel chalcone derivative has antitumor activity in melanoma by inducing DNA damage through the upregulation of ROS products.
Downexpression of HSD17B6 correlates with clinical prognosis and tumor immune infiltrates in hepatocellular carcinoma.
EphA5 knockdown enhances the invasion and migration ability of esophageal squamous cell carcinoma via epithelial-mesenchymal transition through activating Wnt/β-catenin pathway.
MicroRNA-196b-5p promotes malignant progression of colorectal cancer by targeting ING5.
IL-21 promotes osteoblastic differentiation of human valvular interstitial cells through the JAK3/STAT3 pathway.
Interactome analysis of gene expression profiles identifies CDC6 as a potential therapeutic target modified by miR-215-5p in hepatocellular carcinoma.
Fine Particulate Matter (PM(2.5)) upregulates expression of Inflammasome NLRP1 via ROS/NF-κB signaling in HaCaT Cells.
Retinal dehydrogenase 5 (RHD5) attenuates metastasis via regulating HIPPO/YAP signaling pathway in Hepatocellular Carcinoma.
Polysaccharide extracted from WuGuChong reduces high-fat diet-induced obesity in mice by regulating the composition of intestinal microbiota.
Human follicular fluid proteome reveals association between overweight status and oocyte maturation abnormality.
Wnt5a/CaMKII/ERK/CCL2 axis is required for tumor-associated macrophages to promote colorectal cancer progression.
Cdh1 functions as an oncogene by inducing self-renewal of lung cancer stem-like cells via oncogenic pathways.
Poly(U) binding splicing factor 60 promotes renal cell carcinoma growth by transcriptionally upregulating telomerase reverse transcriptase.
Glucocorticoids improve severe or critical COVID-19 by activating ACE2 and reducing IL-6 levels.
MFP-FePt-GO Nanocomposites Promote Radiosensitivity of Non-Small Cell Lung Cancer Via Activating Mitochondrial-Mediated Apoptosis and Impairing DNA Damage Repair.
Polysaccharides isolated from Cordyceps Sinensis contribute to the progression of NASH by modifying the gut microbiota in mice fed a high-fat diet.
Effects of miR-103 by negatively regulating SATB2 on proliferation and osteogenic differentiation of human bone marrow mesenchymal stem cells.
Decorin knockdown affects the gene expression profile of adhesion, growth and extracellular matrix metabolism in C-28/I2 chondrocytes.
S100A6 promotes proliferation and migration of HepG2 cells via increased ubiquitin-dependent degradation of p53.
TiO(2) Nanoparticles Caused DNA Damage in Lung and Extra-Pulmonary Organs Through ROS-Activated FOXO3a Signaling Pathway After Intratracheal Administration in Rats.
Anticancer Effects of Zinc Oxide Nanoparticles Through Altering the Methylation Status of Histone on Bladder Cancer Cells.
Cardiac-Specific Caveolin-3 Overexpression Prevents Post-Myocardial Infarction Ventricular Arrhythmias by Inhibiting Ryanodine Receptor-2 Hyperphosphorylation.
Upregulation of C Terminus of Hsc70-Interacting Protein Attenuates Apoptosis and Procoagulant Activity and Facilitates Brain Repair After Traumatic Brain Injury.
Oxymatrine Liposomes for Intervertebral Disc Treatment: Formulation, in vitro and vivo Assessments.
Plasmacytoid Dendritic Cells Protect Against Middle Cerebral Artery Occlusion Induced Brain Injury by Priming Regulatory T Cells.
Neuroprotection Against Parkinson's Disease Through the Activation of Akt/GSK3β Signaling Pathway by Tovophyllin A.
Neuroprotective Effect of Ketone Metabolism on Inhibiting Inflammatory Response by Regulating Macrophage Polarization After Acute Cervical Spinal Cord Injury in Rats.
Effects of Saikosaponin D on CYP1A2 and CYP2D6 in HepaRG Cells.
Combined Transplantation of Olfactory Ensheathing Cells With Rat Neural Stem Cells Enhanced the Therapeutic Effect in the Retina of RCS Rats.
Effect of Platelet-Activating Factor on Barrier Function of ARPE-19 Cells.
Metformin Inhibits Propofol-Induced Apoptosis of Mouse Hippocampal Neurons HT-22 Through Downregulating Cav-1.
Bergenin Exerts Hepatoprotective Effects by Inhibiting the Release of Inflammatory Factors, Apoptosis and Autophagy via the PPAR-γ Pathway.
RGFP966 Suppresses Tumor Growth and Migration Through Inhibition of EGFR Expression in Hepatocellular Carcinoma Cells in vitro.
Cigarette smoke supports stemness and epithelial-mesenchymal transition in bladder cancer stem cells through SHH signaling.
Combination of astragaloside IV and ACEi ameliorates renal injuries in db/db mice.
FOXO1 and hsa-microRNA-204-5p affect the biologic behavior of MDA-MB-231 breast cancer cells.
Kin17 knockdown suppresses the migration and invasion of cervical cancer cells through NF-κB-Snail pathway.
Kelch-like protein 14 promotes proliferation and migration of ovarian cancer cells.
Overexpression of EPDR1 has an antitumorigenic effect on breast cancer in vitro.
Clinical significance of focal adhesion kinase (FAK) in cervical cancer progression and metastasis.
MicroRNA-451a targets caveolin-1 in stomach cancer cells.
Effect of the SIRT3-AMPK/PPAR pathway on invasion and migration of cervical cancer cells.
Acupuncture Targeting SIRT1 in the Hypothalamic Arcuate Nucleus Can Improve Obesity in High-Fat-Diet-Induced Rats with Insulin Resistance via an Anorectic Effect.
Circular RNA circNELL2 Acts as the Sponge of miR-127-5p to Promote Esophageal Squamous Cell Carcinoma Progression.
TDO Promotes Hepatocellular Carcinoma Progression.
TMED3 Promotes Proliferation and Migration in Breast Cancer Cells by Activating Wnt/β-Catenin Signaling.
Characterization of Triple-Negative Breast Cancer MDA-MB-231 Cell Spheroid Model.
β-Elemene Enhances the Chemotherapeutic Effect of 5-Fluorouracil in Triple-Negative Breast Cancer via PI3K/AKT, RAF-MEK-ErK, and NF-κB Signaling Pathways.
Diosgenin and GSK126 Produce Synergistic Effects on Epithelial-Mesenchymal Transition in Gastric Cancer Cells by Mediating EZH2 via the Rho/ROCK Signaling Pathway.
Comprehensive Transcriptomic Analysis and Experimental Validation Identify lncRNA HOXA-AS2/miR-184/COL6A2 as the Critical ceRNA Regulation Involved in Low-Grade Glioma Recurrence.
miR-877-5p Suppresses Gastric Cancer Cell Proliferation Through Targeting FOXM1.
FANCI Cooperates with IMPDH2 to Promote Lung Adenocarcinoma Tumor Growth via a MEK/ERK/MMPs Pathway.
DNMT1 Enhances the Radiosensitivity of HPV-Positive Head and Neck Squamous Cell Carcinomas via Downregulating SMG1.
Microsatellite Instability-Related ACVR2A Mutations Partially Account for Decreased Lymph Node Metastasis in MSI-H Gastric Cancers.
GPR30 Promotes the Phenotypic Switching of Vascular Smooth Muscle Cells via Activating the AKT and ERK Pathways.
Low-Dose Radiation Promotes Invasion and Migration of A549 Cells by Activating the CXCL1/NF-κB Signaling Pathway.
Cbl Proto-Oncogene B (CBLB) c.197A>T Mutation Induces Mild Metabolic Dysfunction in Partial Type I Multiple Symmetric Lipomatosis (MSL).
RCC2 Interacts with Small GTPase RalA and Regulates Cell Proliferation and Motility in Gastric Cancer.
RSF-1 siRNA Enhances Tumor Radiosensitivity in Cervical Cancer via Enhanced DNA Damage, Cell Cycle Redistribution, and Promotion of Apoptosis.
Long Non-Coding RNA SPRY4-IT1 Reverses Cisplatin Resistance by Downregulating MPZL-1 via Suppressing EMT in NSCLC.
Tumor Suppressor microRNA-138 Suppresses Low-Grade Glioma Development and Metastasis via Regulating IGF2BP2.
Circular RNA 0001313 Knockdown Suppresses Non-Small Cell Lung Cancer Cell Proliferation and Invasion via the microRNA-452/HMGB3/ERK/MAPK Axis.
Knockdown of Circular RNA Hsa_circ_0000714 Can Regulate RAB17 by Sponging miR-370-3p to Reduce Paclitaxel Resistance of Ovarian Cancer Through CDK6/RB Pathway.
DUSP9 Suppresses Proliferation and Migration of Clear Cell Renal Cell Carcinoma via the mTOR Pathway.
Hsa_circRNA_100146 Acts as a Sponge of miR-149-5p in Promoting Bladder Cancer Progression via Regulating RNF2.
Overexpression of RNF126 Promotes the Development of Colorectal Cancer via Enhancing p53 Ubiquitination and Degradation.
17-Allylamino-Demethoxygeldanamycin Ameliorate Microthrombosis Via HSP90/RIP3/NLRP3 Pathway After Subarachnoid Hemorrhage in Rats.
lncRNA USP2-AS1 promotes colon cancer progression by modulating Hippo/YAP1 signaling.
β-catenin regulates myocardial ischemia/reperfusion injury following heterotopic heart transplantation in mice by modulating PTEN pathways.
Homocysteine-induced electrical remodeling via the mediation of IP(3)R1/Nav1.5 signaling pathway.
Astragaloside IV alleviates puromycin aminonucleoside-induced podocyte cytoskeleton injury through the Wnt/PCP pathway.
CircAPLP2 regulates the proliferation and metastasis of colorectal cancer by targeting miR-101-3p to activate the Notch signalling pathway.
Huangqi-Danshen decoction alleviates diabetic nephropathy in db/db mice by inhibiting PINK1/Parkin-mediated mitophagy.
Kaempferol attenuated cisplatin-induced cardiac injury via inhibiting STING/NF-κB-mediated inflammation.
Enzastaurin enhances ATRA-induced differentiation of acute myeloid leukemia cells.
Polydopamine coating with static magnetic field promotes the osteogenic differentiation of human bone-derived mesenchymal stem cells on three-dimensional printed porous titanium scaffolds by upregulation of the BMP-Smads signaling pathway.
EphA5 Silencing Increases the Radiosensitivity of ESCC Cells Through ATM-Dependent Pathway.
miR-758-3p Inhibits Proliferation, Migration, and Invasion of Clear Cell Renal Cell Carcinoma and Predicts Favorable Prognosis.
Exosome-Reversed Chemoresistance to Cisplatin in Non-Small Lung Cancer Through Transferring miR-613.
miR-31-5p Regulates 14-3-3 ɛ to Inhibit Prostate Cancer 22RV1 Cell Survival and Proliferation via PI3K/AKT/Bcl-2 Signaling Pathway.
MiTF is Associated with Chemoresistance to Cisplatin in A549 Lung Cancer Cells via Modulating Lysosomal Biogenesis and Autophagy.
Class I HDAC Inhibitor Improves Synaptic Proteins and Repairs Cytoskeleton Through Regulating Synapse-Related Genes In vitro and In vivo.
FTY720 Prevents Spatial Memory Impairment in a Rat Model of Chronic Cerebral Hypoperfusion via a SIRT3-Independent Pathway.
The Requirement of the C-Terminal Domain of GluA1 in Different Forms of Long-Term Potentiation in the Hippocampus Is Age-Dependent.
Glucosamine-6-Phosphate Isomerase 1 Promotes Tumor Progression and Indicates Poor Prognosis in Hepatocellular Carcinoma.
Down-regulation of USP8 Inhibits Cholangiocarcinoma Cell Proliferation and Invasion.
AOC1 Contributes to Tumor Progression by Promoting the AKT and EMT Pathways in Gastric Cancer.
MicroRNA-1276 Promotes Colon Cancer Cell Proliferation by Negatively Regulating LACTB.
Hyperin Controls the Development and Therapy of Gastric Cancer via Regulating Wnt/β-Catenin Signaling.
MicroRNA-802 Suppresses Tumorigenesis of Colorectal Cancer via Regulating UBN2.
miR-302e Suppresses Glioma Progression by Targeting VEGFA.
Exosomes derived from 5-fluorouracil-resistant colon cancer cells are enriched in GDF15 and can promote angiogenesis.
NFE2L3 promotes malignant behavior and EMT of human hepatocellular carcinoma (HepG2) cells via Wnt/β‑catenin pathway.
Ligand-independent EphB1 signaling mediates TGF-β-activated CDH2 and promotes lung cancer cell invasion and migration.
Analysis of Differentially Expressed Genes in a Chinese Cohort of Esophageal Squamous Cell Carcinoma.
Caffeic Acid Phenethyl Ester Ameliorates Calcification by Inhibiting Activation of the AKT/NF-κB/NLRP3 Inflammasome Pathway in Human Aortic Valve Interstitial Cells.
UVA Induced Oxidative Stress Was Inhibited by Paeoniflorin/Nrf2 Signaling or PLIN2.
Gelatinases Cleave Dentin Sialoprotein Intracellularly.
Salvianolic Acid A Has Anti-Osteoarthritis Effect In Vitro and In Vivo.
Notch3 Modulates Cardiac Fibroblast Proliferation, Apoptosis, and Fibroblast to Myofibroblast Transition via Negative Regulation of the RhoA/ROCK/Hif1α Axis.
Obg-Like ATPase 1 Enhances Chemoresistance of Breast Cancer via Activation of TGF-β/Smad Axis Cascades.
Ursolic Acid Regulates Cell Cycle and Proliferation in Colon Adenocarcinoma by Suppressing Cyclin B1.
Pristimerin Suppresses RANKL-Induced Osteoclastogenesis and Ameliorates Ovariectomy-Induced Bone Loss.
Integrating Network Pharmacology and Experimental Validation to Investigate the Effects and Mechanism of Astragalus Flavonoids Against Hepatic Fibrosis.
Butylphthalide Inhibits Autophagy and Promotes Multiterritory Perforator Flap Survival.
Role of GABRD Gene Methylation in the Nucleus Accumbens in Heroin-Seeking Behavior in Rats.
Elucidation of the Mechanism of Action of Ginseng Against Acute Lung Injury/Acute Respiratory Distress Syndrome by a Network Pharmacology-Based Strategy.
Isorhamnetin Enhances the Radiosensitivity of A549 Cells Through Interleukin-13 and the NF-κB Signaling Pathway.
A Rare KIF1A Missense Mutation Enhances Synaptic Function and Increases Seizure Activity.
Oleoylethanolamide Protects Against Acute Liver Injury by Regulating Nrf-2/HO-1 and NLRP3 Pathways in Mice.
Stimulation of Vibratory Urticaria-Associated Adhesion-GPCR, EMR2/ADGRE2, Triggers the NLRP3 Inflammasome Activation Signal in Human Monocytes.
Isoquercitrin Ameliorates Cisplatin-Induced Nephrotoxicity Via the Inhibition of Apoptosis, Inflammation, and Oxidative Stress.
Poly(dA:dT) Suppresses HSV-2 Infection of Human Cervical Epithelial Cells Through RIG-I Activation.
A Longitudinal Study of T2 Mapping Combined With Diffusion Tensor Imaging to Quantitatively Evaluate Tissue Repair of Rat Skeletal Muscle After Frostbite.
Human Umbilical Cord Mesenchymal Stem Cell Differentiation Into Odontoblast-Like Cells and Endothelial Cells: A Potential Cell Source for Dental Pulp Tissue Engineering.
Tanshinone IIA Inhibits Epithelial-to-Mesenchymal Transition Through Hindering β-Arrestin1 Mediated β-Catenin Signaling Pathway in Colorectal Cancer.
MiR-497-5p Regulates Osteo/Odontogenic Differentiation of Stem Cells From Apical Papilla via the Smad Signaling Pathway by Targeting Smurf2.
A Novel Transcript Isoform of TBK1 Negatively Regulates Type I IFN Production by Promoting Proteasomal Degradation of TBK1 and Lysosomal Degradation of IRF3.
Seneca Valley Virus 3C Protease Inhibits Stress Granule Formation by Disrupting eIF4GI-G3BP1 Interaction.
Evodiamine Attenuates Experimental Colitis Injury Via Activating Autophagy and Inhibiting NLRP3 Inflammasome Assembly.
Chidamide Inhibits Acute Myeloid Leukemia Cell Proliferation by lncRNA VPS9D1-AS1 Downregulation via MEK/ERK Signaling Pathway.
Transcriptomic Analysis of Glycolysis-Related Genes Reveals an Independent Signature of Bladder Carcinoma.
Sleep Deprivation Induces Cognitive Impairment by Increasing Blood-Brain Barrier Permeability via CD44.
Protective effects of taurine against muscle damage induced by diquat in 35 days weaned piglets.
The Endogenous Alterations of the Gut Microbiota and Feces Metabolites Alleviate Oxidative Damage in the Brain of LanCL1 Knockout Mice.
Protective Effects and Possible Mechanisms of Actions of Bushen Cuyun Recipe on Diminished Ovarian Reserve Induced by Cyclophosphamide in Rats.
Mechanical Stretch Induces Smooth Muscle Cell Dysfunction by Regulating ACE2 via P38/ATF3 and Post-transcriptional Regulation by miR-421.
Hepatitis B Core Antigen Impairs the Polarization While Promoting the Production of Inflammatory Cytokines of M2 Macrophages via the TLR2 Pathway.
Investigation of the Lipid-Lowering Mechanisms and Active Ingredients of Danhe Granule on Hyperlipidemia Based on Systems Pharmacology.
Lian Hua Qing Wen Capsules, a Potent Epithelial Protector in Acute Lung Injury Model, Block Proapoptotic Communication Between Macrophages, and Alveolar Epithelial Cells.
Differential Expression and Alternative Splicing of Transcripts Associated With Cisplatin-Induced Chemoresistance in Nasopharyngeal Carcinoma.
Fibroblast Growth Factor 1 Ameliorates Diabetes-Induced Liver Injury by Reducing Cellular Stress and Restoring Autophagy.
C-X-C Motif Chemokine 10 Contributes to the Development of Neuropathic Pain by Increasing the Permeability of the Blood-Spinal Cord Barrier.
Antimicrobial Role of RNASET2 Protein During Innate Immune Response in the Medicinal Leech Hirudo verbana.
Single-Anastomosis Duodenal Jejunal Bypass Improve Glucose Metabolism by Regulating Gut Microbiota and Short-Chain Fatty Acids in Goto-Kakisaki Rats.
Reduced Let-7f in Bone Marrow-Derived Mesenchymal Stem Cells Triggers Treg/Th17 Imbalance in Patients With Systemic Lupus Erythematosus.
Tilianin Extracted From Dracocephalum moldavica L. Induces Intrinsic Apoptosis and Drives Inflammatory Microenvironment Response on Pharyngeal Squamous Carcinoma Cells via Regulating TLR4 Signaling Pathways.
HPV16 E6/E7 promote the translocation and glucose uptake of GLUT1 by PI3K/AKT pathway via relieving miR-451 inhibitory effect on CAB39 in lung cancer cells.
Scutellarein inhibits BLM-mediated pulmonary fibrosis by affecting fibroblast differentiation, proliferation, and apoptosis.
Critical Role of AdipoR1 in Regulating Th17 Cell Differentiation Through Modulation of HIF-1α-Dependent Glycolysis.
Treatment and Prevention of Lung Cancer Using a Virus-Infected Reprogrammed Somatic Cell-Derived Tumor Cell Vaccination (VIReST) Regime.
MiR-362-5p, Which Is Regulated by Long Non-Coding RNA MBNL1-AS1, Promotes the Cell Proliferation and Tumor Growth of Bladder Cancer by Targeting QKI.
Csf2 Attenuated Sepsis-Induced Acute Kidney Injury by Promoting Alternative Macrophage Transition.
Combined Proteome and Transcriptome Analysis of Heat-Primed Azalea Reveals New Insights Into Plant Heat Acclimation Memory.
Maimendong Decoction Improves Pulmonary Function in Rats With Idiopathic Pulmonary Fibrosis by Inhibiting Endoplasmic Reticulum Stress in AECIIs.
The Protective Effect of Luteolin in Glucocorticoid-Induced Osteonecrosis of the Femoral Head.
Gallic Acid Attenuates Angiotensin II-Induced Hypertension and Vascular Dysfunction by Inhibiting the Degradation of Endothelial Nitric Oxide Synthase.
Metformin Mitigates Cartilage Degradation by Activating AMPK/SIRT1-Mediated Autophagy in a Mouse Osteoarthritis Model.
AKT Inhibitor SC66 Inhibits Proliferation and Induces Apoptosis in Human Glioblastoma Through Down-Regulating AKT/β-Catenin Pathway.
De novo Synthesis of SAA1 in the Placenta Participates in Parturition.
MiR-185-5p Protects Against Angiogenesis in Polycystic Ovary Syndrome by Targeting VEGFA.
Inhibition of JNK-Mediated Autophagy Promotes Proscillaridin A- Induced Apoptosis via ROS Generation, Intracellular Ca(+2) Oscillation and Inhibiting STAT3 Signaling in Breast Cancer Cells.
PAQR4 promotes chemoresistance in non-small cell lung cancer through inhibiting Nrf2 protein degradation.
CNTNAP4 deficiency in dopaminergic neurons initiates parkinsonian phenotypes.
SMYD2 suppresses APC2 expression to activate the Wnt/β-catenin pathway and promotes epithelial-mesenchymal transition in colorectal cancer.
Fasudil Promotes α-Synuclein Clearance in an AAV-Mediated α-Synuclein Rat Model of Parkinson's Disease by Autophagy Activation.
Denervation drives skeletal muscle atrophy and induces mitochondrial dysfunction, mitophagy and apoptosis via miR-142a-5p/MFN1 axis.
Promotion of mitochondrial fusion protects against developmental PBDE-47 neurotoxicity by restoring mitochondrial homeostasis and suppressing excessive apoptosis.
Virus-induced p38 MAPK activation facilitates viral infection.
Restoring the epigenetically silenced PCK2 suppresses renal cell carcinoma progression and increases sensitivity to sunitinib by promoting endoplasmic reticulum stress.
TSTA3 facilitates esophageal squamous cell carcinoma progression through regulating fucosylation of LAMP2 and ERBB2.
Truncated HDAC9 identified by integrated genome-wide screen as the key modulator for paclitaxel resistance in triple-negative breast cancer.
Hypergastrinemia Expands Gastric ECL Cells Through CCK2R(+) Progenitor Cells via ERK Activation.
LncRNA CSMD1-1 promotes the progression of Hepatocellular Carcinoma by activating MYC signaling.
Protein acetylation derepresses Serotonin Synthesis to potentiate Pancreatic Beta-Cell Function through HDAC1-PKA-Tph1 signaling.
Diethyldithiocarbamate-copper nanocomplex reinforces disulfiram chemotherapeutic efficacy through light-triggered nuclear targeting.
Selective targeting of the oncogenic KRAS G12S mutant allele by CRISPR/Cas9 induces efficient tumor regression.
Circ-EEF2 facilitated autophagy via interaction with mir-6881-3p and ANXA2 in EOC.
LncRNA NEAT1 facilitates pancreatic cancer growth and metastasis through stabilizing ELF3 mRNA.
Ovary Proteome Analysis Reveals RH36 Regulates Reproduction via Vitellin Uptake Mediated by HSP70 Protein in Hard Ticks.
KLF13 suppresses the proliferation and growth of colorectal cancer cells through transcriptionally inhibiting HMGCS1-mediated cholesterol biosynthesis.
RAC1 Involves in the Radioresistance by Mediating Epithelial-Mesenchymal Transition in Lung Cancer.
Long Noncoding RNA UCA1 Is Related to Autophagy and Apoptosis in Endometrial Stromal Cells.
circ_NOTCH3 Functions as a Protooncogene Competing With miR-205-5p, Modulating KLF12 Expression and Promoting the Development and Progression of Basal-Like Breast Carcinoma.
MLK3 Is Associated With Poor Prognosis in Patients With Glioblastomas and Actin Cytoskeleton Remodeling in Glioblastoma Cells.
Antioxidant Effect of Propofol in Gliomas and Its Association With Divalent Metal Transporter 1.
Characterization of ROS Metabolic Equilibrium Reclassifies Pan-Cancer Samples and Guides Pathway Targeting Therapy.
Long Non-Coding RNA LINC02747 Promotes the Proliferation of Clear Cell Renal Cell Carcinoma by Inhibiting miR-608 and Activating TFE3.
PUF60/AURKA Axis Contributes to Tumor Progression and Malignant Phenotypes in Bladder Cancer.
Vitamin D3 Inhibits Helicobacter pylori Infection by Activating the VitD3/VDR-CAMP Pathway in Mice.
Single-Cell Sequencing of Glioblastoma Reveals Central Nervous System Susceptibility to SARS-CoV-2.
BYSL Promotes Glioblastoma Cell Migration, Invasion, and Mesenchymal Transition Through the GSK-3β/β-Catenin Signaling Pathway.
TDO2 Promotes the EMT of Hepatocellular Carcinoma Through Kyn-AhR Pathway.
Carbohydrate Sulfotransferase 4 Inhibits the Progression of Hepatitis B Virus-Related Hepatocellular Carcinoma and Is a Potential Prognostic Marker in Several Tumors.
FOXK1 Promotes Proliferation and Metastasis of Gallbladder Cancer by Activating AKT/mTOR Signaling Pathway.
Thioguanine Induces Apoptosis in Triple-Negative Breast Cancer by Regulating PI3K-AKT Pathway.
Long Non-coding RNA CCAT1 Acts as an Oncogene and Promotes Sunitinib Resistance in Renal Cell Carcinoma.
CDC27 Promotes Tumor Progression and Affects PD-L1 Expression in T-Cell Lymphoblastic Lymphoma.
Nicotine Reduces Human Brain Microvascular Endothelial Cell Response to Escherichia coli K1 Infection by Inhibiting Autophagy.
Nevirapine Increases Sodium/Iodide Symporter-Mediated Radioiodide Uptake by Activation of TSHR/cAMP/CREB/PAX8 Signaling Pathway in Dedifferentiated Thyroid Cancer.
EGFR/FOXO3A/LXR-α Axis Promotes Prostate Cancer Proliferation and Metastasis and Dual-Targeting LXR-α/EGFR Shows Synthetic Lethality.
miR-15b-5p Promotes Growth and Metastasis in Breast Cancer by Targeting HPSE2.
Conditional ablation of MAPK7 expression in chondrocytes impairs endochondral bone formation in limbs and adaptation of chondrocytes to hypoxia.
The neuro-immune interaction in airway inflammation through TRPA1 expression in CD4+ T cells of asthmatic mice.
Curcumin ameliorates CKD-induced mitochondrial dysfunction and oxidative stress through inhibiting GSK-3β activity.
Resveratrol inhibits the tumor migration and invasion by upregulating TET1 and reducing TIMP2/3 methylation in prostate carcinoma cells.
METTL7B (methyltransferase-like 7B) identification as a novel biomarker for lung adenocarcinoma.
Magnolol inhibits myotube atrophy induced by cancer cachexia through myostatin signaling pathway in vitro.
Bisphenol-A exposure induced neurotoxicity and associated with synapse and cytoskeleton in Neuro-2a cells.
Islet-cell autoantigen 69 accelerates liver regeneration by downregulating Tgfbr1 and attenuating Tgfβ signaling in mice.
GBP1 promotes erlotinib resistance via PGK1‑activated EMT signaling in non‑small cell lung cancer.
ID1 overexpression promotes HCC progression by amplifying the AURKA/Myc signaling pathway.
Protein phosphorylation profiling of peripheral nerve regeneration after autologous nerve grafting.
High glucose condition inhibits trophoblast proliferation, migration and invasion by downregulating placental growth factor expression.
Sodium Butyrate Exacerbates Parkinson's Disease by Aggravating Neuroinflammation and Colonic Inflammation in MPTP-Induced Mice Model.
A Novel Compound YS-5-23 Exhibits Neuroprotective Effect by Reducing β-Site Amyloid Precursor Protein Cleaving Enzyme 1's Expression and H(2)O(2)-Induced Cytotoxicity in SH-SY5Y Cells.
ErbB4 knockdown in serotonergic neurons in the dorsal raphe induces anxiety-like behaviors.
Differential regulation of Actn2 and Actn3 expression during unfolded protein response in C2C12 myotubes.
Mitochondrial superoxide contributes to oxidative stress exacerbated by DNA damage response in RAD51-depleted ovarian cancer cells.
Obesity promotes gastric cancer metastasis via diacylglycerol acyltransferase 2-dependent lipid droplets accumulation and redox homeostasis.
Quercetin alleviated H(2) O(2) -induced apoptosis and steroidogenic impairment in goat luteinized granulosa cells.
Vagus Nerve Stimulation Attenuates Early Traumatic Brain Injury by Regulating the NF-κB/NLRP3 Signaling Pathway.
APC2(CDH1) negatively regulates agrin signaling by promoting the ubiquitination and proteolytic degradation of DOK7.
Selenoprotein T protects against cisplatin-induced acute kidney injury through suppression of oxidative stress and apoptosis.
The MAF1 Phosphoregulatory Region Controls MAF1 Interaction with the RNA Polymerase III C34 Subunit and Transcriptional Repression in Plants.
A paralog-specific role of COPI vesicles in the neuronal differentiation of mouse pluripotent cells.
The deubiquitylase USP2 maintains ErbB2 abundance via counteracting endocytic degradation and represents a therapeutic target in ErbB2-positive breast cancer.
Cardioprotection by isosteviol derivate JC105: A unique drug property to activate ERK1/2 only when cells are exposed to hypoxia-reoxygenation.
Decreased ANGPTL4 impairs endometrial angiogenesis during peri-implantation period in patients with recurrent implantation failure.
Follicle-stimulating hormone impairs dental pulp stem cells odontogenic differentiation.
Musashi2 promotes the progression of pancreatic cancer through a novel ISYNA1-p21/ZEB-1 pathway.
AKR1C2 acts as a targetable oncogene in esophageal squamous cell carcinoma via activating PI3K/AKT signaling pathway.
Aberrant ASPM expression mediated by transcriptional regulation of FoxM1 promotes the progression of gliomas.
UVA influenced the SIRT1-miR-27a-5p-SMAD2-MMP1/COL1/BCL2 axis in human skin primary fibroblasts.
Deubiquitinase USP13 promotes extracellular matrix expression by stabilizing Smad4 in lung fibroblast cells.
TRIM11 promotes breast cancer cell proliferation by stabilizing estrogen receptor α.
Circular RNA hsa_circ_0005556 Accelerates Gastric Cancer Progression by Sponging miR-4270 to Increase MMP19 Expression.
Antiviral immune mechanism of Toll-like receptor 4-mediated human alveolar epithelial cells type Ⅱ.
Oxidation of multiple MiT/TFE transcription factors links oxidative stress to transcriptional control of autophagy and lysosome biogenesis.
Myeloid Cell Expression of LACC1 Is Required for Bacterial Clearance and Control of Intestinal Inflammation.
BAIAP2L2 promotes the progression of gastric cancer via AKT/mTOR and Wnt3a/β-catenin signaling pathways.
PM2.5 compromises antiviral immunity in influenza infection by inhibiting activation of NLRP3 inflammasome and expression of interferon-β.
Novel long non-coding RNA LINC02323 promotes epithelial-mesenchymal transition and metastasis via sponging miR-1343-3p in lung adenocarcinoma.
Icariside Ⅱ, a main compound in Epimedii Folium, induces idiosyncratic hepatotoxicity by enhancing NLRP3 inflammasome activation.
Impaired NHEJ repair in amyotrophic lateral sclerosis is associated with TDP-43 mutations.
Functional regulation of an ancestral RAG transposon ProtoRAG by a trans-acting factor YY1 in lancelet.
Legionella Manipulates Non-canonical SNARE Pairing Using a Bacterial Deubiquitinase.
MiR-126 Regulates Properties of SOX9(+) Liver Progenitor Cells during Liver Repair by Targeting Hoxb6.
Knockdown of TXNDC9 induces apoptosis and autophagy in glioma and mediates cell differentiation by p53 activation.
Autocrine INSL5 promotes tumor progression and glycolysis via activation of STAT5 signaling.
hUMSCs regulate the differentiation of ovarian stromal cells via TGF-β(1)/Smad3 signaling pathway to inhibit ovarian fibrosis to repair ovarian function in POI rats.
Palmatine ameliorates Helicobacter pylori-induced chronic atrophic gastritis by inhibiting MMP-10 through ADAM17/EGFR.
Long non-coding RNA FAM133B-2 represses the radio-resistance of nasopharyngeal cancer cells by targeting miR-34a-5p/CDK6 axis.
Neuroprotective Effect of Piracetam against Cocaine-Induced Neuro Epigenetic Modification of DNA Methylation in Astrocytes.
YAP1 Inhibition in HUVECs Is Associated with Released Exosomes and Increased Hepatocarcinoma Invasion and Metastasis.
Circular RNA circREPS2 Acts as a Sponge of miR-558 to Suppress Gastric Cancer Progression by Regulating RUNX3/β-catenin Signaling.
Fc-Elabela fusion protein attenuates lipopolysaccharide-induced kidney injury in mice.
Porphyromonas gingivalis disrupts vascular endothelial homeostasis in a TLR-NF-κB axis dependent manner.
Anti-bacterial and anti-viral nanchangmycin displays anti-myeloma activity by targeting Otub1 and c-Maf.
Quality Control of ER Membrane Proteins by the RNF185/Membralin Ubiquitin Ligase Complex.
Aldehyde dehydrogenase 2 inhibited oxidized LDL-induced NLRP3 inflammasome priming and activation via attenuating oxidative stress.
KLF16 overexpression deleteriously affects the proliferation and migration of retinoblastoma by transcriptionally repressing BCL2L15.
BAP1 regulates AMPK-mTOR signalling pathway through deubiquitinating and stabilizing tumour-suppressor LKB1.
The microRNA/TET3/REST axis is required for olfactory globose basal cell proliferation and male behavior.
TRIM29 inhibits miR-873-5P biogenesis via CYTOR to upregulate fibronectin 1 and promotes invasion of papillary thyroid cancer cells.
Maternal sevoflurane exposure affects differentiation of hippocampal neural stem cells by regulating miR-410-3p and ATN1.
Antimicrobial Effect of Zophobas morio Hemolymph against Bovine Mastitis Pathogens.
Establishment and characterization of a PCOS and a normal human granulosa cell line.
Small-molecule MMP2/MMP9 inhibitor SB-3CT modulates tumor immune surveillance by regulating PD-L1.
Multi-Compartment, Early Disruption of cGMP and cAMP Signalling in Cardiac Myocytes from the mdx Model of Duchenne Muscular Dystrophy.
Imaging-Based Reporter Systems to Define CVB-Induced Membrane Remodeling in Living Cells.
RNA-binding protein CUGBP1 controls the differential INSR splicing in molecular subtypes of breast cancer cells and affects cell aggressiveness.
MSC-derived exosomes promote recovery from traumatic brain injury via microglia/macrophages in rat.
Peptidome analysis of umbilical cord mesenchymal stem cell (hUC-MSC) conditioned medium from preterm and term infants.
Bardoxolone conjugation enables targeted protein degradation of BRD4.
NIR-II window tracking of hyperglycemia induced intracerebral hemorrhage in cerebral cavernous malformation deficient mice.
CD36 facilitates fatty acid uptake by dynamic palmitoylation-regulated endocytosis.
miR-29a Modulates GSK3β/SIRT1-Linked Mitochondrial Proteostatic Stress to Ameliorate Mouse Non-Alcoholic Steatohepatitis.
NRF2 preserves genomic integrity by facilitating ATR activation and G2 cell cycle arrest.
Complex I mutations synergize to worsen the phenotypic expression of Leber's hereditary optic neuropathy.
Zinc oxide nanoparticles effectively regulate autophagic cell death by activating autophagosome formation and interfering with their maturation.
Cepharanthine and Curcumin inhibited mitochondrial apoptosis induced by PCV2.
Resveratrol alleviates the interleukin-1β-induced chondrocytes injury through the NF-κB signaling pathway.
AKT2 regulates development and metabolic homeostasis via AMPK-depedent pathway in skeletal muscle.
Cyclin G2 Is Involved in the Proliferation of Placental Trophoblast Cells and Their Interactions with Endothelial Cells.
Stachydrine hydrochloride suppresses phenylephrine-induced pathological cardiac hypertrophy by inhibiting the calcineurin/nuclear factor of activated T-cell signalling pathway.
α-Cyperone inhibits the proliferation of human cervical cancer HeLa cells via ROS-mediated PI3K/Akt/mTOR signaling pathway.
Co-inhibition of the TGF-β pathway and the PD-L1 checkpoint by pH-responsive clustered nanoparticles for pancreatic cancer microenvironment regulation and anti-tumor immunotherapy.
MicroRNA-183 exerts a protective role in lupus nephritis through blunting the activation of TGF-β/Smad/TLR3 pathway via reducing Tgfbr1.
The Natural Compound Notopterol Binds and Targets JAK2/3 to Ameliorate Inflammation and Arthritis.
A tRNA-derived fragment (tRF-3001b) aggravates the development of nonalcoholic fatty liver disease by inhibiting autophagy.
Inhibition of PP2A enhances the osteogenic differentiation of human aortic valvular interstitial cells via ERK and p38 MAPK pathways.
Paired box 9 regulates VSMC phenotypic transformation, proliferation, and migration via sonic hedgehog.
Melatonin rescues glucocorticoid-induced inhibition of osteoblast differentiation in MC3T3-E1 cells via the PI3K/AKT and BMP/Smad signalling pathways.
BMSC-derived exosomes alleviate smoke inhalation lung injury through blockade of the HMGB1/NF-κB pathway.
High fat diet impairs spermatogenesis by regulating glucose and lipid metabolism in Sertoli cells.
Sphingomyelin Synthase 2 Participate in the Regulation of Sperm Motility and Apoptosis.
Overactivated sonic hedgehog signaling aggravates intrauterine adhesion via inhibiting autophagy in endometrial stromal cells.
Troxerutin protects against DHT-induced polycystic ovary syndrome in rats.
Tectorigenin enhances PDX1 expression and protects pancreatic β-cells by activating ERK and reducing ER stress.
The protoapigenone analog WYC0209 targets CD133+ cells: A potential adjuvant agent against cancer stem cells in urothelial cancer therapy.
The vicious cycle between ferritinophagy and ROS production triggered EMT inhibition of gastric cancer cells was through p53/AKT/mTor pathway.
Tp53 Suppression Promotes Cardiomyocyte Proliferation during Zebrafish Heart Regeneration.
Downregulation of PIF1, a potential new target of MYCN, induces apoptosis and inhibits cell migration in neuroblastoma cells.
Four active monomers from Moutan Cortex exert inhibitory effects against oxidative stress by activating Nrf2/Keap1 signaling pathway.
FERMT1 promotes gastric cancer progression by activating the NF-κB pathway and predicts poor prognosis.
A novel antiviral lncRNA, EDAL, shields a T309 O-GlcNAcylation site to promote EZH2 lysosomal degradation.
Expression Level of Small Envelope Protein in Addition to Sequence Divergence inside Its Major Hydrophilic Region Contributes to More Efficient Surface Antigen Secretion by Hepatitis B Virus Subgenotype D2 than Subgenotype A2.
Dual targeting of NUAK1 and ULK1 using the multitargeted inhibitor MRT68921 exerts potent antitumor activities.
miR-142-5p and miR-130a-3p regulate pulmonary macrophage polarization and asthma airway remodeling.
MiR-375-3p alleviates the severity of inflammation through targeting YAP1/LEKTI pathway in HaCaT cells.
Genome-wide pathogenesis interpretation using a heat diffusion-based systems genetics method and implications for gene function annotation.
Amyotrophic lateral sclerosis-linked UBQLN2 mutants inhibit endoplasmic reticulum to Golgi transport, leading to Golgi fragmentation and ER stress.
Uncovering the mechanism of Astragali Radix against nephrotic syndrome by intergrating lipidomics and network pharmacology.
Senolytic Agent Navitoclax Inhibits Angiotensin II-Induced Heart Failure in Mice.
miR-29b-3p protects cardiomyocytes against endotoxin-induced apoptosis and inflammatory response through targeting FOXO3A.
MYCT1 inhibits the EMT and migration of laryngeal cancer cells via the SP1/miR-629-3p/ESRP2 pathway.
Blocking NFATc3 ameliorates azoxymethane/dextran sulfate sodium induced colitis-associated colorectal cancer in mice via the inhibition of inflammatory responses and epithelial-mesenchymal transition.
Identification of mecciRNAs and their roles in the mitochondrial entry of proteins.
The support of genetic evidence for cardiovascular risk induced by antineoplastic drugs.
Upregulation of secreted phosphoprotein 1 affects malignant progression, prognosis, and resistance to cetuximab via the KRAS/MEK pathway in head and neck cancer.
MiR-34a suppresses the proliferation and invasion of gastric cancer by modulating PDL1 in the immune microenvironment.
Bovine Milk Exosomes Affect Proliferation and Protect Macrophages against Cisplatin-Induced Cytotoxicity.
Generation of homozygous CRISPRa human induced pluripotent stem cell (hiPSC) lines for sustained endogenous gene activation.
sATP‑binding cassette subfamily G member 2 enhances the multidrug resistance properties of human nasal natural killer/T cell lymphoma side population cells.
NLRC3 silencing accelerates the invasion of hepatocellular carcinoma cell via IL-6/JAK2/STAT3 pathway activation.
Internalization of the TAT-PBX1 fusion protein significantly enhances the proliferation of human hair follicle-derived mesenchymal stem cells and delays their senescence.
Pellino1 Contributes to Morphine Tolerance by Microglia Activation via MAPK Signaling in the Spinal Cord of Mice.
Tissue Inhibitor of Metalloprotease-1 (TIMP-1) Regulates Adipogenesis of Adipose-derived Stem Cells (ASCs) via the Wnt Signaling Pathway in an MMP-independent Manner.
3-Methyladenine Alleviates Experimental Subretinal Fibrosis by Inhibiting Macrophages and M2 Polarization Through the PI3K/Akt Pathway.
The role of Caspase-1/GSDMD-mediated pyroptosis in Taxol-induced cell death and a Taxol-resistant phenotype in nasopharyngeal carcinoma regulated by autophagy.
Zbtb20 deficiency causes cardiac contractile dysfunction in mice.
Endothelial microparticles induced by cyclic stretch activate Src and modulate cell apoptosis.
Xanthatin alleviates airway inflammation in asthmatic mice by regulating the STAT3/NF-κB signaling pathway.
Curcumin suppresses the proliferation and tumorigenicity of Cal27 by modulating cancer-associated fibroblasts of TSCC.
Aloe extract inhibits porcine epidemic diarrhea virus in vitro and in vivo.
Emodin inhibiting neutrophil elastase-induced epithelial-mesenchymal transition through Notch1 signalling in alveolar epithelial cells.
Ulinastatin reduces myocardial injury induced by doxorubicin in SD rats.
Selective blocking of CXCR2 prevents and reverses atrial fibrillation in spontaneously hypertensive rats.
Circular RNA circTET3 mediates migration of rat vascular smooth muscle cells by targeting miR-351-5p.
Resveratrol inhibits hypertrophic scars formation by activating autophagy via the miR-4654/Rheb axis.
PRDX2 plays an oncogenic role in esophageal squamous cell carcinoma via Wnt/β-catenin and AKT pathways.
Autophagy-Sirt3 axis decelerates hematopoietic aging.
Over-activation of NMDA receptors promotes ABCA1 degradation and foam cell formation.
ML-SA1, a selective TRPML agonist, inhibits DENV2 and ZIKV by promoting lysosomal acidification and protease activity.
Perillaldehyde: A promising antifungal agent to treat oropharyngeal candidiasis.
TGF-β1-induced miR-424 promotes pulmonary myofibroblast differentiation by targeting Slit2 protein expression.
Inhibition of RUNX1 promotes cisplatin-induced apoptosis in ovarian cancer cells.
Peli1 impairs microglial Aβ phagocytosis through promoting C/EBPβ degradation.
The Long Noncoding RNA NEAT1 Promotes Sarcoma Metastasis by Regulating RNA Splicing Pathways.
Antidiabetic activity in vitro and in vivo of BDB, a selective inhibitor of protein tyrosine phosphatase 1B, from Rhodomela confervoides.
The human ribosomal protein eL29 binds in vivo to the cognate mRNA by interacting with its coding sequence, as revealed from in-cell cross-linking data.
RAGE Signaling pathway in hippocampus dentate gyrus involved in GLT-1 decrease induced by chronic unpredictable stress in rats.
Melatonin improves hypoxic-ischemic brain damage through the Akt/Nrf2/Gpx4 signaling pathway.
RNA demethylase Alkbh5 is widely expressed in neurons and decreased during brain development.
Inhibition of cell migration and induction of apoptosis by a novel class II histone deacetylase inhibitor, MCC2344.
Enhancing PPARγ by HDAC inhibition reduces foam cell formation and atherosclerosis in ApoE deficient mice.
p53 promotes ZDHHC1-mediated IFITM3 palmitoylation to inhibit Japanese encephalitis virus replication.
STYK1 promotes autophagy through enhancing the assembly of autophagy-specific class III phosphatidylinositol 3-kinase complex I.
Identification of osalmid metabolic profile and active metabolites with anti-tumor activity in human hepatocellular carcinoma cells.
Therapeutic effect of phycocyanin on acute liver oxidative damage caused by X-ray.
miR-483-3p promotes cell proliferation and suppresses apoptosis in rheumatoid arthritis fibroblast-like synoviocytes by targeting IGF-1.
Paired like homeodomain 1 and SAM and SH3 domain-containing 1 in the progression and prognosis of head and neck squamous cell carcinoma.
Lnc-MUC20-9 binds to ROCK1 and functions as a tumor suppressor in bladder cancer.
Matrix metalloprotease-mediated cleavage of neural glial-related cell adhesion molecules activates quiescent olfactory stem cells via EGFR.
Renal asymmetric dimethylarginine inhibits fibrosis.
Enhancing site-specific DNA integration by a Cas9 nuclease fused with a DNA donor-binding domain.
Mir-20a-5p induced WTX deficiency promotes gastric cancer progressions through regulating PI3K/AKT signaling pathway.
Calreticulin promotes EMT in pancreatic cancer via mediating Ca(2+) dependent acute and chronic endoplasmic reticulum stress.
miR-431-5p regulates cell proliferation and apoptosis in fibroblast-like synoviocytes in rheumatoid arthritis by targeting XIAP.
Effect of Zhenxin Xingshui Yizhi Fang on Aβ(25-35) induced expression of related transporters in HBMEC cell model.
Loss of TMEM106B and PGRN leads to severe lysosomal abnormalities and neurodegeneration in mice.
Temporal activation of LRH-1 and RAR-γ in human pluripotent stem cells induces a functional naïve-like state.
Blockade of Glial Connexin 43 Hemichannels Reduces Food Intake.
Defect of SLC38A3 promotes epithelial-mesenchymal transition and predicts poor prognosis in esophageal squamous cell carcinoma.
IGF2BP1 silencing inhibits proliferation and induces apoptosis of high glucose-induced non-small cell lung cancer cells by regulating Netrin-1.
Cancer-associated fibroblasts-derived exosomal miR-17-5p promotes colorectal cancer aggressive phenotype by initiating a RUNX3/MYC/TGF-β1 positive feedback loop.
HIF-1α-Mediated Mitophagy Determines ZnO Nanoparticle-Induced Human Osteosarcoma Cell Death both In Vitro and In Vivo.
Circular RNA circ_PVT1 induces epithelial-mesenchymal transition to promote metastasis of cervical cancer.
Nicotine Causes Nephrotoxicity through the Induction of NLRP6 Inflammasome and Alpha7 Nicotinic Acetylcholine Receptor.
A Dedicated Evolutionarily Conserved Molecular Network Licenses Differentiated Cells to Return to the Cell Cycle.
Myostatin regulates fatty acid desaturation and fat deposition through MEF2C/miR222/SCD5 cascade in pigs.
Inhibition of ROS/NLRP3/Caspase-1 mediated pyroptosis attenuates cadmium-induced apoptosis in duck renal tubular epithelial cells.
PD-1 Regulates GABAergic Neurotransmission and GABA-Mediated Analgesia and Anesthesia.
USP52 regulates DNA end resection and chemosensitivity through removing inhibitory ubiquitination from CtIP.
Functional validation of a human GLUD2 variant in a murine model of Parkinson's disease.
Phosphodiesterase 2A2 regulates mitochondria clearance through Parkin-dependent mitophagy.
Loss of PRCD alters number and packaging density of rhodopsin in rod photoreceptor disc membranes.
Emergence of Carbapenem-Resistant Providencia rettgeri and Providencia stuartii Producing IMP-Type Metallo-β-Lactamase in Japan.
A Regulation Loop between YAP and NR4A1 Balances Cell Proliferation and Apoptosis.
Novel Therapeutic Insights in Dedifferentiated Liposarcoma: A Role for FGFR and MDM2 Dual Targeting.
Targeting interleukin-17 receptor B enhances gemcitabine sensitivity through downregulation of mucins in pancreatic cancer.
Expression of STAT1 is positively correlated with PD-L1 in human ovarian cancer.
Multiple-Purpose Connectivity Map Analysis Reveals the Benefits of Esculetin to Hyperuricemia and Renal Fibrosis.
Quality Control of ER Membrane Proteins by the RNF185/Membralin Ubiquitin Ligase Complex.
Antioxidant Apigenin Relieves Age-Related Muscle Atrophy by Inhibiting Oxidative Stress and Hyperactive Mitophagy and Apoptosis in Skeletal Muscle of Mice.
Autophagy regulates exosome secretion in rat nucleus pulposus cells via the RhoC/ROCK2 pathway.
SARS-CoV-2 targets neurons of 3D human brain organoids.
XK is a partner for VPS13A: a molecular link between Chorea-Acanthocytosis and McLeod Syndrome.
Ambient fine particulate matter induced the elevation of blood pressure through ACE2/Ang(1-7) pathway: The evidence from urine metabolites.
A novel pectin from Polygala tenuifolia blocks Aβ(42) aggregation and production by enhancing insulin-degradation enzyme and neprilysin.
Structures and anti-atherosclerotic effects of 1,6-α-glucans from Fructus Corni.
Melatonin suppresses ER stress-dependent proapoptotic effects via AMPK in bone mesenchymal stem cells during mitochondrial oxidative damage.
BKCa channels regulate the immunomodulatory properties of WJ-MSCs by affecting the exosome protein profiles during the inflammatory response.
Identification of Fibroblast Activation Protein as an Osteogenic Suppressor and Anti-osteoporosis Drug Target.
PERK controls bone homeostasis through the regulation of osteoclast differentiation and function.
The combined usage of Matrine and Osthole inhibited endoplasmic reticulum apoptosis induced by PCV2.
TAp63α targeting of Lgr5 mediates colorectal cancer stem cell properties and sulforaphane inhibition.
USP7 mediates pathological hepatic de novo lipogenesis through promoting stabilization and transcription of ZNF638.
Landscape characterization of chimeric RNAs in colorectal cancer.
The RNA exosome complex degrades expanded hexanucleotide repeat RNA in C9orf72 FTLD/ALS.
3-Mercaptopyruvate sulfurtransferase/hydrogen sulfide protects cerebral endothelial cells against oxygen-glucose deprivation/reoxygenation-induced injury via mitoprotection and inhibition of the RhoA/ROCK pathway.
Type 2 diabetes-induced overactivation of P300 contributes to skeletal muscle atrophy by inhibiting autophagic flux.
Role and mechanism of PI3K/AKT/FoxO1/PDX-1 signaling pathway in functional changes of pancreatic islets in rats after severe burns.
Platycodon grandifloras polysaccharides inhibit mitophagy injury induced by Cr (VI) in DF-1 cells.
Targeting Mitochondria-Located circRNA SCAR Alleviates NASH via Reducing mROS Output.
Amifostine ameliorates induction of experimental autoimmune encephalomyelitis: Effect on reactive oxygen species/NLRP3 pathway.
microRNA-421-3p prevents inflammatory response in cerebral ischemia/reperfusion injury through targeting m6A Reader YTHDF1 to inhibit p65 mRNA translation.
Wilms' tumor 1-associating protein contributes to psoriasis by promoting keratinocytes proliferation via regulating cyclinA2 and CDK2.
PDLIM2 protects articular chondrocytes from lipopolysaccharide-induced apoptosis, degeneration and inflammatory injury through down-regulation of nuclear factor (NF)-κB signaling.
Emodin ameliorates ovalbumin-induced airway remodeling in mice by suppressing airway smooth muscle cells proliferation.
The role of WNT1 mutant variant (WNT1(c.677C>T) ) in osteogenesis imperfecta.
Ginsenoside Rg3 attenuates ovariectomy-induced osteoporosis via AMPK/mTOR signaling pathway.
RSPO3 is a marker candidate for predicting tumor aggressiveness in ovarian cancer.
SOX2 promotes resistance of melanoma with PD-L1 high expression to T-cell-mediated cytotoxicity that can be reversed by SAHA.
The metabolic response to inflammation in astrocytes is regulated by nuclear factor-kappa B signaling.
miR-877-5p antagonizes the promoting effect of SP on the gastric cancer progression.
The molecular basis of tight nuclear tethering and inactivation of cGAS.
Loss of core fucosylation enhances the anticancer activity of cytotoxic T lymphocytes by increasing PD-1 degradation.
N‑linoleyltyrosine protects PC12 cells against oxidative damage via autophagy: Possible involvement of CB1 receptor regulation.
Association of tricellulin expression with poor colorectal cancer prognosis and metastasis.
Caveolin-1 upregulates Fut8 expression by activating the Wnt/β-catenin pathway to enhance HCC cell proliferative and invasive ability.
MG53 protects against contrast-induced acute kidney injury by reducing cell membrane damage and apoptosis.
The role of protein kinase C alpha in tri-ortho-cresyl phosphate-induced autophagy in human neuroblastoma SK-N-SH cells.
Nanog mediates tobacco smoke-induced enhancement of renal cancer stem cell properties.
In vivo immunotoxicity of Gd(2) O(3) :Eu(3+) nanoparticles and the associated molecular mechanism.
SNORA71B promotes breast cancer cells across blood-brain barrier by inducing epithelial-mesenchymal transition.
RBMX is required for activation of ATR on repetitive DNAs to maintain genome stability.
MyoD1 suppresses cell migration and invasion by inhibiting FUT4 transcription in human gastric cancer cells.
TRPV4 promotes acoustic wave-mediated BBB opening via Ca(2+)/PKC-δ pathway.
Hydroquinone inhibits PRV infection in neurons in vitro and in vivo.
ndufa7 plays a critical role in cardiac hypertrophy.
Down-regulated HDAC3 elevates microRNA-495-3p to restrain epithelial-mesenchymal transition and oncogenicity of melanoma cells via reducing TRAF5.
Long noncoding RNA TCONS-00106987 promotes atrial electrical remodelling during atrial fibrillation by sponging miR-26 to regulate KCNJ2.
Cathepsin L promotes angiogenesis by regulating the CDP/Cux/VEGF-D pathway in human gastric cancer.
Overexpression of G3BP1 facilitates the progression of colon cancer by activating β‑catenin signaling.
miR‑155 modulates high glucose‑induced cardiac fibrosis via the Nrf2/HO‑1 signaling pathway.
The AKT inhibitor MK2206 suppresses airway inflammation and the pro‑remodeling pathway in a TDI‑induced asthma mouse model.
LncRNA GAS5 inhibits NLRP3 inflammasome activation-mediated pyroptosis in diabetic cardiomyopathy by targeting miR-34b-3p/AHR.
Crosstalk between pleural mesothelial cell and lung fibroblast contributes to pulmonary fibrosis.
Paired associated magnetic stimulation promotes neural repair in the rat middle cerebral artery occlusion model of stroke.
TRAF6 Activates Fibroblasts to Cancer-Associated Fibroblasts through FGF19 in Tumor Microenvironment to Benefit the Malignant Phenotype of Melanoma Cells.
Pomegranate flower extract bidirectionally regulates the proliferation, differentiation and apoptosis of 3T3-L1 cells through regulation of PPARγ expression mediated by PI3K-AKT signaling pathway.
Type 2 diabetes mellitus facilitates endometrial hyperplasia progression by activating the proliferative function of mucin O-glycosylating enzyme GALNT2.
Indirubin alleviates bleomycin-induced pulmonary fibrosis in mice by suppressing fibroblast to myofibroblast differentiation.
Exosome secreted by human gingival fibroblasts in radiation therapy inhibits osteogenic differentiation of bone mesenchymal stem cells by transferring miR-23a.
The long noncoding RNA FTX promotes a malignant phenotype in bone marrow mesenchymal stem cells via the miR-186/c-Met axis.
Enhancement of anti-acne effect of Scutellaria baicalensis extract by fermentation with symbiotic fungus Penicillium decumbens.
Nucleoredoxin interaction with flightless-I/actin complex is differentially altered in alcoholic liver disease.
NLRC3-like 1 inhibits NOD1-RIPK2 pathway via targeting RIPK2.
TGF-β2 interfering oligonucleotides used as adjuvants for microbial vaccines.
Overexpression of Dnmt3a ameliorates diabetic muscle atrophy by modulating the Pten/Akt pathway.
Two resveratrol analogs, pinosylvin and 4,4'-dihydroxystilbene, improve oligoasthenospermia in a mouse model by attenuating oxidative stress via the Nrf2-ARE pathway.
MiR-124-3p promotes trophoblast cell HTR-8/SVneo pyroptosis by targeting placental growth factor.
MiR-185-5p ameliorates endoplasmic reticulum stress and renal fibrosis by downregulation of ATF6.
Cholestasis impairs hepatic lipid storage via AMPK and CREB signaling in hepatitis B virus surface protein transgenic mice.
Inositol-Requiring Enzyme 1α Promotes Zika Virus Infection through Regulation of Stearoyl Coenzyme A Desaturase 1-Mediated Lipid Metabolism.
Oroxylin A alleviates immunoparalysis of CLP mice by degrading CHOP through interacting with FBXO15.
Long-wave Ultraviolet Ray Promotes Inflammation in Keloid-derived Fibroblasts by Activating P38-NFκB1 Signaling Pathway.
Macrophage-derived small extracellular vesicles promote biomimetic mineralized collagen-mediated endogenous bone regeneration.
miR-206 as a prognostic and sensitivity biomarker for platinum chemotherapy in epithelial ovarian cancer.
Smyd3-PARP16 axis accelerates unfolded protein response and vascular aging.
Grape Seed Proanthocyanidins Induce Apoptosis and Cell Cycle Arrest of HepG2 Cells Accompanied by Induction of the MAPK Pathway and NAG-1.
IQGAP3 interacts with Rad17 to recruit the Mre11-Rad50-Nbs1 complex and contributes to radioresistance in lung cancer.
Calnexin mediates the maturation of GPI-anchors through ER retention.
Catalysis of proline isomerization and molecular chaperone activity in a tug-of-war.
SAHA Overcomes 5-FU Resistance in IFIT2-Depleted Oral Squamous Cell Carcinoma Cells.
Effect of conditioned medium from neural stem cells on glioma progression and its protein expression profile analysis.
Legumain is a predictor of all-cause mortality and potential therapeutic target in acute myocardial infarction.
Protective Effects of Fucoxanthin on High Glucose- and 4-Hydroxynonenal (4-HNE)-Induced Injury in Human Retinal Pigment Epithelial Cells.
The effect of whey protein on viral infection and replication of SARS-CoV-2 and pangolin coronavirus in vitro.
Two novel likely pathogenic variants of HARS2 identified in a Chinese family with sensorineural hearing loss.
Loss of Atg7 causes chaotic nucleosome assembly of mouse bone marrow CD11b(+)Ly6G(-) myeloid cells.
RNAi-mediated silencing of Trichinella spiralis serpin-type serine protease inhibitors results in a reduction in larval infectivity.
Calcium and TRPV4 promote metastasis by regulating cytoskeleton through the RhoA/ROCK1 pathway in endometrial cancer.
TDP-43 interacts with amyloid-β, inhibits fibrillization, and worsens pathology in a model of Alzheimer's disease.
MiR-103a-3p promotes tumour glycolysis in colorectal cancer via hippo/YAP1/HIF1A axis.
Inhibition of ferroptosis alleviates atherosclerosis through attenuating lipid peroxidation and endothelial dysfunction in mouse aortic endothelial cell.
Velvet antler polypeptide prevents the disruption of hepatic tight junctions via inhibiting oxidative stress in cholestatic mice and liver cell lines.
Loss of TDP-43 in astrocytes leads to motor deficits by triggering A1-like reactive phenotype and triglial dysfunction.
The TLR3/IRF1/Type III IFN Axis Facilitates Antiviral Responses against Enterovirus Infections in the Intestine.
Urocortin participates in LPS-induced apoptosis of THP-1 macrophages via S1P-cPLA2 signaling pathway.
Identification and functional analysis of fourteen NR5A1 variants in patients with the 46 XY disorders of sex development.
Inhibiting Rab27a in renal tubular epithelial cells attenuates the inflammation of diabetic kidney disease through the miR-26a-5p/CHAC1/NF-kB pathway.
USP33 regulates c-Met expression by deubiquitinating SP1 to facilitate metastasis in hepatocellular carcinoma.
Macrophage-Derived IL-1β Regulates Emergency Myelopoiesis via the NF-κB and C/ebpβ in Zebrafish.
Targeting HMGB3/hTERT axis for radioresistance in cervical cancer.
Autophagic blockage by bismuth sulfide nanoparticles inhibits migration and invasion of HepG2 cells.
The role of macrophage migration inhibitory factor in promoting benign prostatic hyperplasia epithelial cell growth by modulating COX-2 and P53 signaling.
Electroacupuncture alleviates Parkinson disease and regulates the expression of brain-gut peptides.
Tomatidine inhibits porcine epidemic diarrhea virus replication by targeting 3CL protease.
A CRISPR-Cas9 screen identifies mitochondrial translation as an essential process in latent KSHV infection of human endothelial cells.
Inhibition of notch enhances the anti-atherosclerotic effects of LXR agonists while reducing fatty liver development in ApoE-deficient mice.
Discovery of novel anti-angiogenesis agents. Part 11: Development of PROTACs based on active molecules with potency of promoting vascular normalization.
L-lactate preconditioning promotes plasticity-related proteins expression and reduces neurological deficits by potentiating GPR81 signaling in rat traumatic brain injury model.
Circ-PGAM1 promotes malignant progression of epithelial ovarian cancer through regulation of the miR-542-3p/CDC5L/PEAK1 pathway.
Inhibition of miR-103a-3p suppresses the proliferation in oral squamous cell carcinoma cells via targeting RCAN1.
Grape Extract Activates Brown Adipose Tissue Through Pathway Involving the Regulation of Gut Microbiota and Bile Acid.
Lysyl-tRNA synthetase produces diadenosine tetraphosphate to curb STING-dependent inflammation.
CtBP1 transactivates RAD51 and confers cisplatin resistance to breast cancer cells.
TRIM22 inhibits endometrial cancer progression through the NOD2/NF‑κB signaling pathway and confers a favorable prognosis.
Mechanism of aberrant long non-coding RNA expression in an adriamycin-resistant liver cancer cell strain.
MicroRNA‑145‑5p inhibits osteosarcoma cell proliferation by targeting E2F transcription factor 3.
DNA methylation‑regulated miR‑155‑5p depresses sensitivity of esophageal carcinoma cells to radiation and multiple chemotherapeutic drugs via suppression of MAP3K10.
Ganoderic acid hinders renal fibrosis via suppressing the TGF-β/Smad and MAPK signaling pathways.
PBX1 promotes development of natural killer cells by binding directly to the Nfil3 promoter.
Cognitive improvement and synaptic deficit attenuation by a multifunctional carbazole-based cyanine in AD mice model through regulation of Ca(2+)/CaMKII/CREB signaling pathway.
Yeast β-D-glucan exerts antitumour activity in liver cancer through impairing autophagy and lysosomal function, promoting reactive oxygen species production and apoptosis.
BMX activates Wnt/β-catenin signaling pathway to promote cell proliferation and migration in breast cancer.
Autophagy related 4B, upregulated by HIF-1α, attenuates the sensitivity to cisplatin in nasopharyngeal carcinoma cells.
LncRNA ZEB2-AS1 promotes the proliferation, migration and invasion of esophageal squamous cell carcinoma cell through miR-574-3p/HMGA2 axis.
miR-181a/b-5p ameliorates inflammatory response in monocrotaline-induced pulmonary arterial hypertension by targeting endocan.
Altered circadian clock as a novel therapeutic target for constant darkness-induced insulin resistance and hyperandrogenism of polycystic ovary syndrome.
Mitophagy is involved in chromium (VI)-induced mitochondria damage in DF-1 cells.
Chlorogenic acid rescues zearalenone induced injury to mouse ovarian granulosa cells.
SOX9 represses hepatitis B virus replication through binding to HBV EnhII/Cp and inhibiting the promoter activity.
Modulation of NR1 receptor by CaMKIIα plays an important role in chronic itch development in mice.
RIP3/MLKL-mediated neuronal necroptosis induced by methamphetamine at 39°C.
Activation of sirtuin1 protects against ischemia/reperfusion-induced acute kidney injury.
The natural compound andrographolide inhibits human aortic valve interstitial cell calcification via the NF-kappa B/Akt/ERK pathway.
Melanoma suppression by quercein is correlated with RIG-I and type I interferon signaling.
Silencing METTL3 inhibits the proliferation and invasion of osteosarcoma by regulating ATAD2.
ALDH1A1 maintains the cancer stem-like cells properties of esophageal squamous cell carcinoma by activating the AKT signal pathway and interacting with β-catenin.
Upregulation of nuclear factor (erythroid-derived 2)-like 2 protein level in the human colorectal adenocarcinoma cell line DLD-1 by a heterocyclic organobismuth(III) compound: Effect of organobismuth(III) compound on NRF2 signaling.
KIF2A promotes the progression via AKT signaling pathway and is upregulated by transcription factor ETV4 in human gastric cancer.
β-elemene suppresses the malignant behavior of esophageal cancer cells by regulating the phosphorylation of AKT.
DACT2 regulates structural and electrical atrial remodeling in atrial fibrillation.
Protein kinase CK2 participates in estrogen-mediated endothelial progenitor cell homing to endometriotic lesions through stromal cells in a stromal cell-derived factor-1- CXCR4-dependent manner.
BMP8A promotes survival and drug resistance via Nrf2/TRIM24 signaling pathway in clear cell renal cell carcinoma.
Epithelial V-like antigen 1 promotes hepatocellular carcinoma growth and metastasis via the ERBB-PI3K-AKT pathway.
Hydrogen inhibits the osteoclastogenesis of mouse bone marrow mononuclear cells.
Whole transcriptome sequencing reveals dexmedetomidine-improves postoperative cognitive dysfunction in rats via modulating lncRNA.
Morphometric, Hemodynamic, and Multi-Omics Analyses in Heart Failure Rats with Preserved Ejection Fraction.
Rapid Neutralization Testing System for Zika Virus Based on an Enzyme-Linked Immunospot Assay.
Perturbation of phosphoglycerate kinase 1 (PGK1) only marginally affects glycolysis in cancer cells.
PHLDA2 regulates EMT and autophagy in colorectal cancer via the PI3K/AKT signaling pathway.
Analysis of the role of the interleukins in colon cancer.
Neuropeptide Y1 receptor antagonist promotes osteoporosis and microdamage repair and enhances osteogenic differentiation of bone marrow stem cells via cAMP/PKA/CREB pathway.
Self-responsive co-delivery system for remodeling tumor intracellular microenvironment to promote PTEN-mediated anti-tumor therapy.
Small-molecule inhibition of aging-associated chromosomal instability delays cellular senescence.
Naringin inhibits autophagy mediated by PI3K-Akt-mTOR pathway to ameliorate endothelial cell dysfunction induced by high glucose/high fat stress.
Downregulation of GLYR1 contributes to microsatellite instability colorectal cancer by targeting p21 via the p38MAPK and PI3K/AKT pathways.
Kalirin Interacts with TRAPP and Regulates Rab11 and Endosomal Recycling.
The heterocyclic compound Tempol inhibits the growth of cancer cells by interfering with glutamine metabolism.
Prenatal bisphenol A exposure contributes to Tau pathology: Potential roles of CDK5/GSK3β/PP2A axis in BPA-induced neurotoxicity.
Pharmacogenomic Analysis Reveals CCNA2 as a Predictive Biomarker of Sensitivity to Polo-Like Kinase I Inhibitor in Gastric Cancer.
Design, Synthesis, and Biological Evaluation of HSP90 Inhibitor-SN38 Conjugates for Targeted Drug Accumulation.
PAX6 contributes to the activation and proliferation of hepatic stellate cells via activating Hedgehog/GLI1 pathway.
Synergistic antifibrotic effects of miR-451 with miR-185 partly by co-targeting EphB2 on hepatic stellate cells.
Glycolytic and lipid oxidative metabolic programs are essential for freshly-isolated regulatory T cells in mice with sepsis.
circStrn3 is involved in bone cancer pain regulation in a rat model.
Circular RNA circNRIP1 promotes migration and invasion in cervical cancer by sponging miR-629-3p and regulating the PTP4A1/ERK1/2 pathway.
Evodiamine via targeting nNOS and AMPA receptor GluA1 inhibits nitroglycerin-induced migraine-like response.
Delivery of oligonucleotides to bone marrow to modulate ferrochelatase splicing in a mouse model of erythropoietic protoporphyria.
Exogenous Therapeutics of Microrna-29a Attenuates Development of Hepatic Fibrosis in Cholestatic Animal Model through Regulation of Phosphoinositide 3-Kinase p85 Alpha.
KMT2A regulates cervical cancer cell growth through targeting VDAC1.
Inhibition of protein phosphatase methylesterase 1 dysregulates MAP kinase signaling and attenuates muscle cell differentiation.
Anti-inflammatory activity of berberine in non-alcoholic fatty liver disease via the Angptl2 pathway.
Fatty Acid Synthase Inhibitor G28 Shows Anticancer Activity in EGFR Tyrosine Kinase Inhibitor Resistant Lung Adenocarcinoma Models.
Bone-targeted lncRNA OGRU alleviates unloading-induced bone loss via miR-320-3p/Hoxa10 axis.
High-mobility group box 1 promotes epithelial-to-mesenchymal transition in crystalline silica induced pulmonary inflammation and fibrosis.
Knockdown of the Ribosomal Protein eL29 in Mammalian Cells Leads to Significant Changes in Gene Expression at the Transcription Level.
TACC3 promotes prostate cancer cell proliferation and restrains primary cilium formation.
Time serial transcriptome reveals Cyp2c29 as a key gene in hepatocellular carcinoma development.
MEL endomorphins act as potent inflammatory analgesics with the inhibition of activated non-neuronal cells and modulation of pro-inflammatory cytokines.
Heterogeneous nuclear ribonucleoprotein A3 controls mitotic progression of neural progenitors via interaction with cohesin.
UBQLN2 Promotes the Production of Type I Interferon via the TBK1-IRF3 Pathway.
Membrane-Associated α-Tubulin Is Less Acetylated in Postmortem Prefrontal Cortex from Depressed Subjects Relative to Controls: Cytoskeletal Dynamics, HDAC6, and Depression.
Discovery of a novel third-generation EGFR inhibitor and identification of a potential combination strategy to overcome resistance.
Evidence for Cytoprotective Effect of Carbon Monoxide Donor in the Development of Acute Esophagitis Leading to Acute Esophageal Epithelium Lesions.
EFEMP2 indicates assembly of M0 macrophage and more malignant phenotypes of glioma.
SETDB1 promotes the progression of colorectal cancer via epigenetically silencing p21 expression.
POTEE promotes colorectal carcinoma progression via activating the Rac1/Cdc42 pathway.
RNA-Seq Reveals Underlying Transcriptomic Mechanisms of Bone Marrow-Derived Mesenchymal Stem Cells in the Regulation of Microglia-Mediated Neuroinflammation After Subarachnoid Hemorrhage.
Type 3 adenylyl cyclase in the main olfactory epithelium participates in depression-like and anxiety-like behaviours.
A modular biomimetic strategy for the synthesis of macrolide P-glycoprotein inhibitors via Rh-catalyzed C-H activation.
Demethyleneberberine attenuates concanavalin A-induced autoimmune hepatitis in mice through inhibition of NF-κB and MAPK signaling.
Downregulation of ubiquitin-specific protease 2 possesses prognostic and diagnostic value and promotes the clear cell renal cell carcinoma progression.
Genome sequencing analysis of a family with a child displaying severe abdominal distention and recurrent hypoglycemia.
Characterization of seminal plasma proteomic alterations associated with the IVF and rescue-ICSI pregnancy in assisted reproduction.
Mouse model of metformin-induced diarrhea.
Rosmarinic acid exerts an anticancer effect on osteosarcoma cells by inhibiting DJ-1 via regulation of the PTEN-PI3K-Akt signaling pathway.
Elevated myocardial SORBS2 and the underlying implications in left ventricular noncompaction cardiomyopathy.
Thymosinβ4 alleviates cholestatic liver fibrosis in mice through downregulating PDGF/PDGFR and TGFβ/Smad pathways.
MicroRNA‑137 suppresses the proliferation, migration and invasion of cholangiocarcinoma cells by targeting WNT2B.
Linc00261 inhibits metastasis and the WNT signaling pathway of pancreatic cancer by regulating a miR‑552‑5p/FOXO3 axis.
Aurora B induces epithelial-mesenchymal transition by stabilizing Snail1 to promote basal-like breast cancer metastasis.
The Wnt/β-catenin/VASP positive feedback loop drives cell proliferation and migration in breast cancer.
Dehydrocostus lactone inhibits NLRP3 inflammasome activation by blocking ASC oligomerization and prevents LPS-mediated inflammation in vivo.
Identification of apoptosis-associated protein factors distinctly expressed in cigarette smoke condensate-exposed airway bronchial epithelial cells.
HUWE1 promotes EGFR ubiquitination and degradation to protect against renal tubulointerstitial fibrosis.
Upregulation of KSRP by miR-27b attenuates schistosomiasis-induced hepatic fibrosis by targeting TGF-β1.
Jmjd3 regulates inflammasome activation and aggravates DSS-induced colitis in mice.
Inflammatory-sensitive CHI3L1 protects nucleus pulposus via AKT3 signaling during intervertebral disc degeneration.
Do You Know the Details of Your PAX8 Antibody? Monoclonal PAX8 (MRQ-50) Is Not Expressed in a Series of 45 Medullary Thyroid Carcinomas.
A serpin from the tick Rhipicephalus haemaphysaloides: Involvement in vitellogenesis.
Atlastin-1 modulates seizure activity and neuronal excitability.
Immunoproteasome subunit β5i regulates diet-induced atherosclerosis through altering MERTK-mediated efferocytosis in Apoe knockout mice.
Rutin promotes osteogenic differentiation of periodontal ligament stem cells through the GPR30-mediated PI3K/AKT/mTOR signaling pathway.
Oxymatrine suppresses IL-1β-induced degradation of the nucleus pulposus cell and extracellular matrix through the TLR4/NF-κB signaling pathway.
Anti-ageing effects of red ginseng on female Drosophila melanogaster.
MiR-133a alleviates renal injury caused by sepsis by targeting BNIP3L.
Dioscin inhibits the growth of human osteosarcoma by inducing G2/M-phase arrest, apoptosis, and GSDME-dependent cell death in vitro and in vivo.
Autophagy inhibition via Becn1 downregulation improves the mesenchymal stem cells antifibrotic potential in experimental liver fibrosis.
Decreasing New York esophageal squamous cell carcinoma 1 expression inhibits multiple myeloma growth and osteolytic lesions.
Silencing of tumor-suppressive NR_023387 in renal cell carcinoma via promoter hypermethylation and HNF4A deficiency.
Polystyrene nanoplastic induces ROS production and affects the MAPK-HIF-1/NFkB-mediated antioxidant system in Daphnia pulex.
The tacrolimus-induced glucose homeostasis imbalance in terms of the liver: From bench to bedside.
miR-181a negatively modulates synaptic plasticity in hippocampal cultures and its inhibition rescues memory deficits in a mouse model of Alzheimer's disease.
Ubiquitination of P53 by E3 ligase MKRN2 promotes melanoma cell proliferation.
MicroRNA-103a-3p potentiates chemoresistance to cisplatin in non-small cell lung carcinoma by targeting neurofibromatosis 1.
The functional role of the C-terminal tail of the human ribosomal protein uS19.
A long noncoding RNA sensitizes genotoxic treatment by attenuating ATM activation and homologous recombination repair in cancers.
Hypericin attenuates nonalcoholic fatty liver disease and abnormal lipid metabolism via the PKA-mediated AMPK signaling pathway in vitro and in vivo.
Synthesis of dual functional procaine-derived carbon dots for bioimaging and anticancer therapy.
Matrix mechanics and water permeation regulate extracellular vesicle transport.
A new abietane diterpenoid from Ajuga ovalifolia var. calantha induces human lung epithelial A549 cell apoptosis by inhibiting SHP2.
LongShengZhi capsule inhibits doxorubicin-induced heart failure by anti-oxidative stress.
DKC1 enhances angiogenesis by promoting HIF-1α transcription and facilitates metastasis in colorectal cancer.
IL1β inhibits differentiation of cementoblasts via microRNA-325-3p.
G protein-coupled receptor kinase-2: A potential biomarker for early diabetic cardiomyopathy.
Cannabinoid receptor 1 knockout alleviates hepatic steatosis by downregulating perilipin 2.
ETS2 promotes epithelial-to-mesenchymal transition in renal fibrosis by targeting JUNB transcription.
MicroRNA-217-5p ameliorates endothelial cell apoptosis induced by ox-LDL by targeting CLIC4.
Melatonin Promotes the Proliferation of Chicken Sertoli Cells by Activating the ERK/Inhibin Alpha Subunit Signaling Pathway.
Molecular hydrogen attenuates methamphetamine-induced behavioral sensitization and activation of ERK-ΔFosB signaling in the mouse nucleus accumbens.
Topology, Antiviral Functional Residues and Mechanism of IFITM1.
Novel HSP90-PI3K Dual Inhibitor Suppresses Melanoma Cell Proliferation by Interfering with HSP90-EGFR Interaction and Downstream Signaling Pathways.
Transcription co-activator P300 activates Elk1-aPKC-ι signaling mediated epithelial-to-mesenchymal transition and malignancy in hepatocellular carcinoma.
Anti-toll-like receptor 2 antibody ameliorates hepatic injury, inflammation, fibrosis and steatosis in obesity-related metabolic disorder rats via regulating MAPK and NF-κB pathways.
Pathway-specific enzymes from bamboo and crop leaves biosynthesize anti-nociceptive C-glycosylated flavones.
Human polymorphisms in GSDMD alter the inflammatory response.
lncRNA RMST Suppressed GBM Cell Mitophagy through Enhancing FUS SUMOylation.
The 25(OH)D/VDR signaling may play a role in major depression.
TRPC6-dependent Ca(2+) signaling mediates airway inflammation in response to oxidative stress via ERK pathway.
PTEN inhibitor VO-OHpic attenuates GC-associated endothelial progenitor cell dysfunction and osteonecrosis of the femoral head via activating Nrf2 signaling and inhibiting mitochondrial apoptosis pathway.
Genetic inactivation of mTORC1 or mTORC2 in neurons reveals distinct functions in glutamatergic synaptic transmission.
5-HT(1A)R alleviates Aβ-induced cognitive decline and neuroinflammation through crosstalk with NF-κB pathway in mice.
Nanofiber Alignment Mediates the Pattern of Single Cell Migration.
Qingyi decoction protects against myocardial injuries induced by severe acute pancreatitis.
The Agpat4/LPA axis in colorectal cancer cells regulates antitumor responses via p38/p65 signaling in macrophages.
Long non-coding RNA HAL suppresses the migration and invasion of serous ovarian cancer by inhibiting EMT signaling pathway.
Posttranslational lysine 2-hydroxyisobutyrylation of human sperm tail proteins affects motility.
The C-terminal domain of feline and bovine SAMHD1 proteins has a crucial role in lentiviral restriction.
Design, Synthesis, and Biological Evaluation of Imidazo[1,2-a]pyridine Derivatives as Novel PI3K/mTOR Dual Inhibitors.
Changed PGA and POSTN levels in choroid plexus are associated with depressive-like behaviors in mice.
KLF5 Is Crucial for Androgen-AR Signaling to Transactivate Genes and Promote Cell Proliferation in Prostate Cancer Cells.
Dual regulation of p53 by the ribosome maturation factor SBDS.
Cervical carcinoma risk associate with genetic polymorphisms of NEIL2 gene in Chinese population and its significance as predictive biomarker.
Inhibiting both proline biosynthesis and lipogenesis synergistically suppresses tumor growth.
Complement Signals Determine Opposite Effects of B Cells in Chemotherapy-Induced Immunity.
AQP1 modulates tendon stem/progenitor cells senescence during tendon aging.
ADORA1 Inhibition Promotes Tumor Immune Evasion by Regulating the ATF3-PD-L1 Axis.
PHLDA1 is a new therapeutic target of oxidative stress and ischemia reperfusion-induced myocardial injury.
Design, synthesis, biological evaluation of 6-(2-amino-1H-benzo[d]imidazole-6-yl)quinazolin-4(3H)-one derivatives as novel anticancer agents with Aurora kinase inhibition.
Mesencephalic astrocyte-derived neurotrophic factor ameliorates steatosis in HepG2 cells by regulating hepatic lipid metabolism.
Pellino1 regulates neuropathic pain as well as microglial activation through the regulation of MAPK/NF-κB signaling in the spinal cord.
Western diet induces severe nonalcoholic steatohepatitis, ductular reaction, and hepatic fibrosis in liver CGI-58 knockout mice.
Dietary Compound Isoliquiritigenin, an Antioxidant from Licorice, Suppresses Triple-Negative Breast Tumor Growth via Apoptotic Death Program Activation in Cell and Xenograft Animal Models.
Controlled release of adenosine from core-shell nanofibers to promote bone regeneration through STAT3 signaling pathway.
LncRNA HCP5 promotes cell proliferation and inhibits apoptosis via miR-27a-3p/IGF-1 axis in human granulosa-like tumor cell line KGN.
AEBP1 Promotes the Occurrence and Development of Abdominal Aortic Aneurysm by Modulating Inflammation via the NF-κB Pathway.
Microcystins-LR induced apoptosis via S-nitrosylation of GAPDH in colorectal cancer cells.
miR-144 Mediates High Fat-Induced Changes of Cholesterol Metabolism via Direct Regulation of C/EBPα in the Liver and Isolated Hepatocytes of Yellow Catfish.
Suppression of high-mobility group box 1 ameliorates xerostomia in a Sjögren syndrome-triggered mouse model.
Nbr1-regulated autophagy in Lactoferrin-induced osteoblastic differentiation.
Antibody microarray analysis of serum inflammatory cytokines in patients with calcific aortic valve disease.
Fam83d modulates MAP kinase and AKT signaling and is induced during neurogenic skeletal muscle atrophy.
Expression, location and biological effects of four and a half LIM domain protein 2 (FHL2) on granulosa cells in ovine.
TNF-α/HMGB1 inflammation signalling pathway regulates pyroptosis during liver failure and acute kidney injury.
TGM3 promotes epithelial-mesenchymal transition and hepatocellular carcinogenesis and predicts poor prognosis for patients after curative resection.
Enhanced tenogenic differentiation and tendon-like tissue formation by Scleraxis overexpression in human amniotic mesenchymal stem cells.
Effects of hyperoxia exposure on the expression of Nrf2 and heme oxygenase-1 in lung tissues of premature rats.
EMT related circular RNA expression profiles identify circSCYL2 as a novel molecule in breast tumor metastasis.
Alda-1, an Aldehyde Dehydrogenase 2 Agonist, Improves Cutaneous Wound Healing by Activating Epidermal Keratinocytes via Akt/GSK-3β/β-Catenin Pathway.
Leucine-rich repeat containing 4 act as an autophagy inhibitor that restores sensitivity of glioblastoma to temozolomide.
Altered expression of AKT1 and P38A in the colons of patients with Hirschsprung's disease.
Ghrelin promotes neural differentiation of adipose tissue-derived mesenchymal stem cell via AKT/mTOR and β-catenin signaling pathways.
Berardinelli-Seip congenital lipodystrophy 2/SEIPIN determines brown adipose tissue maintenance and thermogenic programing.
Neuroprotective effects of miR-532-5p against ischemic stroke.
Upregulation of miR-219a-5p Decreases Cerebral Ischemia/Reperfusion Injury In Vitro by Targeting Pde4d.
Integrin β3, a RACK1 interacting protein, is critical for porcine reproductive and respiratory syndrome virus infection and NF-κB activation in Marc-145 cells.
The E3 ubiquitin ligase TRIM7 suppressed hepatocellular carcinoma progression by directly targeting Src protein.
Inflammatory injury and mitophagy induced by Cr(VI) in chicken liver.
Knockdown of p66ShcA activates Nrf2 pathway to protect cardiomyocytes from oxidative stress and inflammation induced by H2O2.
MiR-126 regulated myocardial autophagy on myocardial infarction.
Seizure-induced impairment in neuronal ketogenesis: Role of zinc-α2-glycoprotein in mitochondria.
Endogenous thrombopoietin promotes non-small-cell lung carcinoma cell proliferation and migration by regulating EGFR signalling.
A study of the effects of SGLT-2 inhibitors on diabetic cardiomyopathy through miR-30d/KLF9/VEGFA pathway.
Analysis of deep sequencing exosome-microRNA expression profile derived from CP-II reveals potential role of gga-miRNA-451 in inflammation.
An upstream open reading frame regulates vasculogenic mimicry of glioma via ZNRD1-AS1/miR-499a-5p/ELF1/EMI1 pathway.
Rice Protein Exerts Endogenous Antioxidant Capacity via Methionine Sulfoxide Reductase and the Nrf2 Antioxidant System Independent of Age.
BMP4 resets mouse epiblast stem cells to naive pluripotency through ZBTB7A/B-mediated chromatin remodelling.
MicroRNA‑28 promotes the proliferation of non‑small‑cell lung cancer cells by targeting PTEN.
Bisphenol a affects endometrial stromal cells decidualization, involvement of epigenetic regulation.
Biointerface anisotropy modulates migration of breast cancer cell.
PTPN3 Inhibits the Growth and Metastasis of Clear Cell Renal Cell Carcinoma via Inhibition of PI3K/AKT Signaling.
Meprin-α (Mep1A) enhances TNF-α secretion by mast cells and aggravates abdominal aortic aneurysms.
DHA attenuates Aβ-induced necroptosis through the RIPK1/RIPK3 signaling pathway in THP-1 monocytes.
Modified citrus pectin ameliorates myocardial fibrosis and inflammation via suppressing galectin-3 and TLR4/MyD88/NF-κB signaling pathway.
Interference with SMO increases chemotherapy drug sensitivity of A2780/DDP cells by inhibiting the Hh/Gli signaling pathway.
Long noncoding RNA linc00467 plays an oncogenic role in hepatocellular carcinoma by regulating the miR-18a-5p/NEDD9 axis.
Activator of thyroid and retinoid receptor increases sorafenib resistance in hepatocellular carcinoma by facilitating the Warburg effect.
Oxidative stress induces monocyte-to-myofibroblast transdifferentiation through p38 in pancreatic ductal adenocarcinoma.
T-cell activation and immune memory enhancement induced by irreversible electroporation in pancreatic cancer.
The effect of swimming exercise and diet on the hypothalamic inflammation of ApoE-/- mice based on SIRT1-NF-κB-GnRH expression.
Highly expressed STAT1 contributes to the suppression of stemness properties in human paclitaxel-resistant ovarian cancer cells.
Gan Shen Fu Fang ameliorates liver fibrosis in vitro and in vivo by inhibiting the inflammatory response and extracellular signal-regulated kinase phosphorylation.
Progranulin inhibits LPS-induced macrophage M1 polarization via NF-кB and MAPK pathways.
Role of ANKHD1/LINC00346/ZNF655 Feedback Loop in Regulating the Glioma Angiogenesis via Staufen1-Mediated mRNA Decay.
lncRNA LINC00665 Stabilized by TAF15 Impeded the Malignant Biological Behaviors of Glioma Cells via STAU1-Mediated mRNA Degradation.
Minocycline alleviates NLRP3 inflammasome-dependent pyroptosis in monosodium glutamate-induced depressive rats.
Loss of CHCHD2 and CHCHD10 activates OMA1 peptidase to disrupt mitochondrial cristae phenocopying patient mutations.
Integrative Analysis of NSCLC Identifies LINC01234 as an Oncogenic lncRNA that Interacts with HNRNPA2B1 and Regulates miR-106b Biogenesis.
SRSF10 inhibits biogenesis of circ-ATXN1 to regulate glioma angiogenesis via miR-526b-3p/MMP2 pathway.
Deletion of the Impg2 gene causes the degeneration of rod and cone cells in mice.
Pyrroloquinoline Quinone Inhibits Oxidative Stress in Rats with Diabetic Nephropathy.
Cimifugin ameliorates imiquimod-induced psoriasis by inhibiting oxidative stress and inflammation via NF-κB/MAPK pathway.
STEAP1 facilitates metastasis and epithelial-mesenchymal transition of lung adenocarcinoma via the JAK2/STAT3 signaling pathway.
Chi-miR-30b-5p inhibits dermal papilla cells proliferation by targeting CaMKIIδ gene in cashmere goat.
The PABPC5/HCG15/ZNF331 Feedback Loop Regulates Vasculogenic Mimicry of Glioma via STAU1-Mediated mRNA Decay.
Overexpression of YBX1 Promotes Pancreatic Ductal Adenocarcinoma Growth via the GSK3B/Cyclin D1/Cyclin E1 Pathway.
RBFOX1 Regulates the Permeability of the Blood-Tumor Barrier via the LINC00673/MAFF Pathway.
MicroRNA-675-3p regulates IL-1β-stimulated human chondrocyte apoptosis and cartilage degradation by targeting GNG5.
Circular RNA circ_0111277 attenuates human trophoblast cell invasion and migration by regulating miR-494/HTRA1/Notch-1 signal pathway in pre-eclampsia.
Targeted Delivery of Notch Inhibitor Attenuates Obesity-Induced Glucose Intolerance and Liver Fibrosis.
α7nAchR mediates transcutaneous auricular vagus nerve stimulation-induced neuroprotection in a rat model of ischemic stroke by enhancing axonal plasticity.
Analysis of RAS protein interactions in living cells reveals a mechanism for pan-RAS depletion by membrane-targeted RAS binders.
Immune activation of murine RAW264.7 macrophages by sonicated and alkalized paramylon from Euglena gracilis.
LUZP1, a novel regulator of primary cilia and the actin cytoskeleton, is a contributing factor in Townes-Brocks Syndrome.
Long noncoding RNA LINC00314 facilitates osteogenic differentiation of adipose-derived stem cells through the hsa-miR-129-5p/GRM5 axis via the Wnt signaling pathway.
Pannexin1 Channel Inhibitor ((10)panx) Protects Against Transient Focal Cerebral Ischemic Injury by Inhibiting RIP3 Expression and Inflammatory Response in Rats.
IL-4 Switches Microglia/macrophage M1/M2 Polarization and Alleviates Neurological Damage by Modulating the JAK1/STAT6 Pathway Following ICH.
Perinatal low-dose PBDE-47 exposure hampered thyroglobulin turnover and induced thyroid cell apoptosis by triggering ER stress and lysosomal destabilization contributing to thyroid toxicity in adult female rats.
β-catenin-mediated Wnt signal transduction proceeds through an endocytosis-independent mechanism.
Major depression accompanied with inflammation and multiple cytokines alterations: Evidences from clinical patients to macaca fascicularis and LPS-induced depressive mice model.
PLK1 Inhibition alleviates transplant-associated obliterative bronchiolitis by suppressing myofibroblast differentiation.
Non-Esterified Fatty Acid-Induced Reactive Oxygen Species Mediated Granulosa Cells Apoptosis Is Regulated by Nrf2/p53 Signaling Pathway.
Qian Yang Yu Yin Granule protects against hypertension-induced renal injury by epigenetic mechanism linked to Nicotinamide N-Methyltransferase (NNMT) expression.
Ginsenoside Rg3 promotes regression from hepatic fibrosis through reducing inflammation-mediated autophagy signaling pathway.
Circular RNA circZNF566 promotes hepatocellular carcinoma progression by sponging miR-4738-3p and regulating TDO2 expression.
TSPO ligand Ro5-4864 modulates microglia/macrophages polarization after subarachnoid hemorrhage in mice.
Knockdown of fibronectin extra domain B suppresses TGF-β1-mediated cell proliferation and collagen deposition in keloid fibroblasts via AKT/ERK signaling pathway.
Circular RNA (circRNA) CDYL Induces Myocardial Regeneration by ceRNA After Myocardial Infarction.
M6A-related bioinformatics analysis reveals that HNRNPC facilitates progression of OSCC via EMT.
Extrasynaptic CaMKIIα is involved in the antidepressant effects of ketamine by downregulating GluN2B receptors in an LPS-induced depression model.
SHQ1 is an ER stress response gene that facilitates chemotherapeutics-induced apoptosis via sensitizing ER-stress response.
Downregulation of BACH1 Protects AGAINST Cerebral Ischemia/Reperfusion Injury through the Functions of HO-1 and NQO1.
Phenylephrine alleviates (131)I damage in submandibular gland through promoting endogenous stem cell regeneration via lissencephaly-1 upregulation.
DNMT1-mediated Foxp3 gene promoter hypermethylation involved in immune dysfunction caused by arsenic in human lymphocytes.
ARHGEF10L expression regulates cell proliferation and migration in gastric tumorigenesis.
Costunolide improved dextran sulfate sodium-induced acute ulcerative colitis in mice through NF-κB, STAT1/3, and Akt signaling pathways.
Acarbose, as a potential drug, effectively blocked the dynamic metastasis of EV71 from the intestine to the whole body.
A mitophagic response to iron overload-induced oxidative damage associated with the PINK1/Parkin pathway in pancreatic beta cells.
Generation of B6-Ddx4(em1(CreERT2)Utr) , a novel CreERT2 knock-in line, for germ cell lineage by CRISPR/Cas9.
Crocin Reverses Depression-Like Behavior in Parkinson Disease Mice via VTA-mPFC Pathway.
HSulf‑1 and palbociclib exert synergistic antitumor effects on RB‑positive triple‑negative breast cancer.
Circulating Exosomes From Lipopolysaccharide-Induced Ards Mice Trigger Endoplasmic Reticulum Stress in Lung Tissue.
Matrix Metalloproteinase 11 as a Novel Tumor Promoter and Diagnostic and Prognostic Biomarker for Pancreatic Ductal Adenocarcinoma.
Methionine Enkephalin Suppresses Osteocyte Apoptosis Induced by Compressive Force through Regulation of Nuclear Translocation of NFATc1.
S100A14 suppresses metastasis of nasopharyngeal carcinoma by inhibition of NF-kB signaling through degradation of IRAK1.
Transcription factorIRX5 promotes hepatocellular carcinoma proliferation and inhibits apoptosis by regulating the p53 signalling pathway.
Thyrotropin receptor signaling deficiency impairs spatial learning and memory in mice.
Porcine RACK1 negatively regulates the infection of classical swine fever virus and the NF-κB activation in PK-15 cells.
UHRF1 predicts poor prognosis by triggering cell cycle in lung adenocarcinoma.
p75NTR optimizes the osteogenic potential of human periodontal ligament stem cells by up-regulating α1 integrin expression.
Progress in the research of p53 tumour suppressor activity controlled by Numb in triple-negative breast cancer.
Autophagy assuages myocardial infarction through Nrf2 signaling activation-mediated reactive oxygen species clear.
Reversal of prolonged obesity-associated cerebrovascular dysfunction by inhibiting microglial Tak1.
Wnt10b-overexpressing umbilical cord mesenchymal stem cells promote critical size rat calvarial defect healing by enhanced osteogenesis and VEGF-mediated angiogenesis.
Antioxidant-related catalase CTA1 regulates development, aflatoxin biosynthesis, and virulence in pathogenic fungus Aspergillus flavus.
High expression of CDCA7 predicts tumor progression and poor prognosis in human colorectal cancer.
MicroRNA‑93 promotes angiogenesis and attenuates remodeling via inactivation of the Hippo/Yap pathway by targeting Lats2 after myocardial infarctionω.
LncRNA MALAT1 affects the migration and invasion of trophoblast cells by regulating FOS expression in early-onset preeclampsia.
Metastasis-associated gene MAPK15 promotes the migration and invasion of osteosarcoma cells via the c-Jun/MMPs pathway.
PRR11 and SKA2 promote the proliferation, migration and invasion of esophageal carcinoma cells.
miR-96-5p regulated TGF-β/SMAD signaling pathway and suppressed endometrial cell viability and migration via targeting TGFBR1.
GL-V9 reverses adriamycin resistance in hepatocellular carcinoma cells by affecting JNK2-related autophagy.
Artemisinin inhibits the replication of flaviviruses by promoting the type I interferon production.
Label-Free Quantitative Proteomic Profiling of LAD2 Mast Cell Releasates Reveals the Mechanism of Tween-80-Induced Anaphylactoid Reaction.
miR-429-CRKL axis regulates clear cell renal cell carcinoma malignant progression through SOS1/MEK/ERK/MMP2/MMP9 pathway.
Isocitrate dehydrogenase 2 contributes to radiation resistance of oesophageal squamous cell carcinoma via regulating mitochondrial function and ROS/pAKT signalling.
Integration of in vitro data from three dimensionally cultured HepaRG cells and physiologically based pharmacokinetic modeling for assessment of acetaminophen hepatotoxicity.
High expression of KITLG is a new hallmark activating the MAPK pathway in type A and AB thymoma.
Changes in Nup62 content affect contact-induced differentiation of cultured myoblasts.
RDP3, A Novel Antigout Peptide Derived from Water Extract of Rice.
Matrine inhibits the growth of natural killer/T-cell lymphoma cells by modulating CaMKIIγ-c-Myc signaling pathway.
Opposing biological functions of the cytoplasm and nucleus DAXX modified by SUMO-2/3 in gastric cancer.
κB-Ras and Ral GTPases regulate acinar to ductal metaplasia during pancreatic adenocarcinoma development and pancreatitis.
Cerebral Blood Flow-Guided Manipulation of Arterial Blood Pressure Attenuates Hippocampal Apoptosis After Asphyxia-Induced Cardiac Arrest in Rats.
CXCL5 promotes gastric cancer metastasis by inducing epithelial-mesenchymal transition and activating neutrophils.
TRIM24 facilitates antiviral immunity through mediating K63-linked TRAF3 ubiquitination.
Synthesis of a Hexavalent Betulinic Acid Derivative as a Hemagglutinin-Targeted Influenza Virus Entry Inhibitor.
Spermidine activates RIP1 deubiquitination to inhibit TNF-α-induced NF-κB/p65 signaling pathway in osteoarthritis.
Loss of HMGCS2 Enhances Lipogenesis and Attenuates the Protective Effect of the Ketogenic Diet in Liver Cancer.
Apoptotic neurodegeneration in whitefly promotes the spread of TYLCV.
Assessment of insulin resistance in the skeletal muscle of mice using positron emission tomography/computed tomography imaging.
Application of Antibodies to Neuronally Expressed Nogo-A Increases Neuronal Survival and Neurite Outgrowth.
EN2 as an oncogene promotes tumor progression via regulating CCL20 in colorectal cancer.
MCF7 Spheroid Development: New Insight about Spatio/Temporal Arrangements of TNTs, Amyloid Fibrils, Cell Connections, and Cellular Bridges.
LncRNA PVT1 promotes gemcitabine resistance of pancreatic cancer via activating Wnt/β-catenin and autophagy pathway through modulating the miR-619-5p/Pygo2 and miR-619-5p/ATG14 axes.
Sensitive Signal Amplifying a Diagnostic Biochip Based on a Biomimetic Periodic Nanostructure for Detecting Cancer Exosomes.
CircATRNL1 promotes epithelial-mesenchymal transition in endometriosis by upregulating Yes-associated protein 1 in vitro.
The Impact of ALS-Associated Genes hnRNPA1, MATR3, VCP and UBQLN2 on the Severity of TDP-43 Aggregation.
mTORC1-dependent TFEB nucleus translocation and pro-survival autophagy induced by zeolitic imidazolate framework-8.
Suppression of PTTG1 inhibits cell angiogenesis, migration and invasion in glioma cells.
Correlation between the HIF-1α/Notch signaling pathway and Modic changes in nucleus pulposus cells isolated from patients with low back pain.
Gold Nanoparticles Induce Tumor Vessel Normalization and Impair Metastasis by Inhibiting Endothelial Smad2/3 Signaling.
Structural and Biological Basis of Alphacoronavirus nsp1 Associated with Host Proliferation and Immune Evasion.
The cross-talk between DDR1 and STAT3 promotes the development of hepatocellular carcinoma.
Histone deacetylase 4 inhibits NF-κB activation by facilitating IκBα sumoylation.
FLIM-FRET-Based Structural Characterization of a Class-A GPCR Dimer in the Cell Membrane.
Glucosylation by the Legionella Effector SetA Promotes the Nuclear Localization of the Transcription Factor TFEB.
LINC00266-1/miR-548c-3p/SMAD2 feedback loop stimulates the development of osteosarcoma.
Ddx56 maintains proliferation of mouse embryonic stem cells via ribosome assembly and interaction with the Oct4/Sox2 complex.
Dopaminergic neurodegeneration induced by Parkinson's disease-linked G2019S LRRK2 is dependent on kinase and GTPase activity.
The food contaminant deoxynivalenol provokes metabolic impairments resulting in non-alcoholic fatty liver (NAFL) in mice.
CTCF promotes colorectal cancer cell proliferation and chemotherapy resistance to 5-FU via the P53-Hedgehog axis.
Leukemogenic Chromatin Alterations Promote AML Leukemia Stem Cells via a KDM4C-ALKBH5-AXL Signaling Axis.
SIRT1 alleviates high-magnitude compression-induced senescence in nucleus pulposus cells via PINK1-dependent mitophagy.
The urea transporter UT-A1 plays a predominant role in a urea-dependent urine-concentrating mechanism.
A Nimbolide-Based Kinase Degrader Preferentially Degrades Oncogenic BCR-ABL.
RNF126-Mediated Reubiquitination Is Required for Proteasomal Degradation of p97-Extracted Membrane Proteins.
Intracellular expression of arginine deiminase activates the mitochondrial apoptosis pathway by inhibiting cytosolic ferritin and inducing chromatin autophagy.
BMMSC-sEV-derived miR-328a-3p promotes ECM remodeling of damaged urethral sphincters via the Sirt7/TGFβ signaling pathway.
Nedd8-activating enzyme inhibitor MLN4924 (Pevonedistat), inhibits miR-1303 to suppress human breast cancer cell proliferation via targeting p27(Kip1).
Effective-component compatibility of Bufei Yishen formula II inhibits mucus hypersecretion of chronic obstructive pulmonary disease rats by regulating EGFR/PI3K/mTOR signaling.
ZIC2 is downregulated and represses tumor growth via the regulation of STAT3 in breast cancer.
Excessive Polyamine Generation in Keratinocytes Promotes Self-RNA Sensing by Dendritic Cells in Psoriasis.
Circular RNA CDR1as Exerts Oncogenic Properties Partially through Regulating MicroRNA 641 in Cholangiocarcinoma.
CPEB3 inhibits epithelial-mesenchymal transition by disrupting the crosstalk between colorectal cancer cells and tumor-associated macrophages via IL-6R/STAT3 signaling.
Synaptopodin-2 promotes hepatocellular carcinoma metastasis via calcineurin-induced nuclear-cytoplasmic translocation.
ETV4 is a theranostic target in clear cell renal cell carcinoma that promotes metastasis by activating the pro-metastatic gene FOSL1 in a PI3K-AKT dependent manner.
MiR-920 promotes osteogenic differentiation of human bone mesenchymal stem cells by targeting HOXA7.
TCF7L2 rs290487 C allele aberrantly enhances hepatic gluconeogenesis through allele-specific changes in transcription and chromatin binding.
GABRG2 Deletion Linked to Genetic Epilepsy with Febrile Seizures Plus Affects the Expression of GABA(A) Receptor Subunits and Other Genes at Different Temperatures.
miR-744-5p mediates lncRNA HOTTIP to regulate the proliferation and apoptosis of papillary thyroid carcinoma cells.
Erythropoietin-producing hepatocellular receptor A7 restrains estrogen negative feedback of luteinizing hormone via ephrin A5 in the hypothalamus of female rats.
Circulating extracellular vesicles from patients with valvular heart disease induce neutrophil chemotaxis via FOXO3a and the inhibiting role of dexmedetomidine.
A role of the frontotemporal lobar degeneration risk factor TMEM106B in myelination.
LncRNA MBNL1-AS1 represses cell proliferation and enhances cell apoptosis via targeting miR-135a-5p/PHLPP2/FOXO1 axis in bladder cancer.
Microglial activation contributes to depressive-like behavior in dopamine D3 receptor knockout mice.
CHK2-FOXK axis promotes transcriptional control of autophagy programs.
MiR-let-7d-3p regulates IL-17 expression through targeting AKT1/mTOR signaling in CD4(+) T cells.
PRRX1-induced epithelial-to-mesenchymal transition in salivary adenoid cystic carcinoma activates the metabolic reprogramming of free fatty acids to promote invasion and metastasis.
SIRT3 promotes the invasion and metastasis of cervical cancer cells by regulating fatty acid synthase.
The aqueous extract of Gentianella acuta improves isoproterenol‑induced myocardial fibrosis via inhibition of the TGF‑β1/Smads signaling pathway.
Metformin facilitates the proliferation, migration, and osteogenic differentiation of periodontal ligament stem cells in vitro.
RNA-binding motif protein 10 induces apoptosis and suppresses proliferation by activating p53.
Dichloroacetate restores colorectal cancer chemosensitivity through the p53/miR-149-3p/PDK2-mediated glucose metabolic pathway.
Autophagy and Ubiquitin-Proteasome System Coordinate to Regulate the Protein Quality Control of Neurodegenerative Disease-Associated DCTN1.
Fabrication of porous bovine pericardium scaffolds incorporated with bFGF for tissue engineering applications.
MiR-146a down-regulates inflammatory response by targeting TLR3 and TRAF6 in Coxsackievirus B infection.
In utero hypoxia altered Ang II-induced contraction via PKCβ in fetal cerebral arteries.
Hic-5 deficiency protects cerulein-induced chronic pancreatitis via down-regulation of the NF-κB (p65)/IL-6 signalling pathway.
MicroRNA-29b-3p suppresses oral squamous cell carcinoma cell migration and invasion via IL32/AKT signalling pathway.
Protective mechanism of SIRT1 on Hcy-induced atrial fibrosis mediated by TRPC3.
Long noncoding RNA MAGI1-IT1 regulates cardiac hypertrophy by modulating miR-302e/DKK1/Wnt/beta-catenin signaling pathway.
Targeting the WEE1 kinase strengthens the antitumor activity of imatinib via promoting KIT autophagic degradation in gastrointestinal stromal tumors.
Exome sequencing revealed Notch ligand JAG1 as a novel candidate gene for familial exudative vitreoretinopathy.
Activity and mechanism of flavokawain A in inhibiting P-glycoprotein expression in paclitaxel resistance of lung cancer.
Receptor tyrosine kinase inhibitors block proliferation of TGEV mainly through p38 mitogen-activated protein kinase pathways.
Functional heritage: the evolution of chimeric RNA into a gene.
Activation of PPARA-mediated autophagy reduces Alzheimer disease-like pathology and cognitive decline in a murine model.
FGF9 knockout in GABAergic neurons induces apoptosis and inflammation via the Fas/caspase-3 pathway in the cerebellum of mice.
Alpha-hemolysin of uropathogenic Escherichia coli induces GM-CSF-mediated acute kidney injury.
Osthole inhibits cell proliferation by regulating the TGF-β1/Smad/p38 signaling pathways in pulmonary arterial smooth muscle cells.
Long noncoding RNA CASC21 exerts an oncogenic role in colorectal cancer through regulating miR-7-5p/YAP1 axis.
Convallatoxin induces HaCaT cell necroptosis and ameliorates skin lesions in psoriasis-like mouse models.
Involvement of the p38 MAPK-pHsp27 pathway in vascular hyporeactivity induced by obstructive jaundice in rats.
Resveratrol induces depletion of TRAF6 and suppresses prostate cancer cell proliferation and migration.
Anti-inflammation effects of injectable platelet-rich fibrin via macrophages and dendritic cells.
Overexpression of human wtTDP-43 causes impairment in hippocampal plasticity and behavioral deficits in CAMKII-tTa transgenic mouse model.
Tamoxifen induces fatty liver disease in breast cancer through the MAPK8/FoxO pathway.
Decreased DHRS2 expression is associated with HDACi resistance and poor prognosis in ovarian cancer.
SLC6A8 Knockdown Suppresses the Invasion and Migration of Human Hepatocellular Carcinoma Huh-7 and Hep3B Cells.
Desloratadine, a Novel Antigrowth Reagent for Bladder Cancer.
c-Abl-p38α signaling pathway mediates dopamine neuron loss in trigeminal neuralgia.
Satellite glial cells in sensory ganglia express functional transient receptor potential ankyrin 1 that is sensitized in neuropathic and inflammatory pain.
Chemokine receptor CXCR4 activates the RhoA/ROCK2 pathway in spinal neurons that induces bone cancer pain.
Scorpion alleviates bone cancer pain through inhibition of bone destruction and glia activation.
STAT3 Activation-Induced Fatty Acid Oxidation in CD8(+) T Effector Cells Is Critical for Obesity-Promoted Breast Tumor Growth.
CD2AP links actin to PI3 kinase activity to extend epithelial cell height and constrain cell area.
A novel IFNα-induced long noncoding RNA negatively regulates immunosuppression by interrupting H3K27 acetylation in head and neck squamous cell carcinoma.
An Alu Element Insertion in Intron 1 Results in Aberrant Alternative Splicing of APOBEC3G Pre-mRNA in Northern Pig-Tailed Macaques (Macaca leonina) That May Reduce APOBEC3G-Mediated Hypermutation Pressure on HIV-1.
Isoliquiritigenin inhibits the proliferation, migration and metastasis of Hep3B cells via suppressing cyclin D1 and PI3K/AKT pathway.
17β-estradiol binding to ERα promotes the progression of prolactinoma through estrogen-response element-induced CaBP-9k up-regulation.
ADAM12 is A Potential Therapeutic Target Regulated by Hypomethylation in Triple-Negative Breast Cancer.
The synthetic cannabinoid dehydroxylcannabidiol restores the function of a major GABA(A) receptor isoform in a cell model of hyperekplexia.
Inhibition of long non-coding RNA metastasis-associated lung adenocarcinoma transcript 1 attenuates high glucose-induced cardiomyocyte apoptosis via regulation of miR-181a-5p.
Synthesis, characterization, and antitumor properties of Au(i)-thiourea complexes.
Hedgehog signaling promotes sorafenib resistance in hepatocellular carcinoma patient-derived organoids.
Mechanical force regulation of YAP by F-actin and GPCR revealed by super-resolution imaging.
Scutellarin inhibition of the rosuvastatin uptake in rat hepatocytes and the competition for organic anion transporting polypeptide 1B1 in HEK293T cells.
Proteomic and lipidomic analysis of exosomes derived from ovarian cancer cells and ovarian surface epithelial cells.
Inhibitory Activity of a Scorpion Defensin BmKDfsin3 against Hepatitis C Virus.
Photocrosslinking Activity-Based Probes for Ubiquitin RING E3 Ligases.
Dysregulation of BDNF/TrkB signaling mediated by NMDAR/Ca(2+)/calpain might contribute to postoperative cognitive dysfunction in aging mice.
High RhCG expression predicts poor survival and promotes migration and proliferation of gastric cancer via keeping intracellular alkaline.
linc01088 promotes cell proliferation by scaffolding EZH2 and repressing p21 in human non-small cell lung cancer.
Intermittent hypoxia mediated by TSP1 dependent on STAT3 induces cardiac fibroblast activation and cardiac fibrosis.
Targeting 7-Dehydrocholesterol Reductase Integrates Cholesterol Metabolism and IRF3 Activation to Eliminate Infection.
Impact of GFRA1 gene reactivation by DNA demethylation on prognosis of patients with metastatic colon cancer.
Synaptic density marker SV2A is reduced in schizophrenia patients and unaffected by antipsychotics in rats.
FHL3 promotes pancreatic cancer invasion and metastasis through preventing the ubiquitination degradation of EMT associated transcription factors.
RETRACTED: Endogenous production of C-C motif chemokine ligand 2 by nasopharyngeal carcinoma cells drives radioresistance-associated metastasis.
Yap/Taz are required for establishing the cerebellar radial glia scaffold and proper foliation.
Endothelial microvesicles induced by physiological cyclic stretch inhibit ICAM1-Dependent leukocyte adhesion.
miR-181b-5p inhibits endothelial-mesenchymal transition in monocrotaline-induced pulmonary arterial hypertension by targeting endocan and TGFBR1.
Hepatitis B virus-triggered PTEN/β-catenin/c-Myc signaling enhances PD-L1 expression to promote immune evasion.
Role of the autotaxin-lysophosphatidic acid axis in glaucoma, aqueous humor drainage and fibrogenic activity.
Attenuation of secondary damage and Aβ deposits in the ipsilateral thalamus of dMCAO rats through reduction of cathepsin B by bis(propyl)-cognitin, a multifunctional dimer.
Identification of chemoresistance-related mRNAs based on gemcitabine-resistant pancreatic cancer cell lines.
Interferon gamma inhibits CXCL8-CXCR2 axis mediated tumor-associated macrophages tumor trafficking and enhances anti-PD1 efficacy in pancreatic cancer.
The key role of macrophage depolarization in the treatment of COPD with ergosterol both in vitro and in vivo.
LL-37 restored glucocorticoid sensitivity impaired by virus dsRNA in lung.
Icariside II improves myocardial fibrosis in spontaneously hypertensive rats by inhibiting collagen synthesis.
Activation of CRHR1 contributes to cerebral endothelial barrier impairment via cPLA(2) phosphorylation in experimental ischemic stroke.
Alveolar Stretch Activation of Endothelial Piezo1 Protects Adherens Junctions and Lung Vascular Barrier.
Long non‑coding RNA CASC2 suppresses pancreatic cancer cell growth and progression by regulating the miR‑24/MUC6 axis.
Epiregulin promotes trophoblast epithelial-mesenchymal transition through poFUT1 and O-fucosylation by poFUT1 on uPA.
Long noncoding RNA NEAT1 is involved in the protective effect of Klotho on renal tubular epithelial cells in diabetic kidney disease through the ERK1/2 signaling pathway.
miR-1294 alleviates epithelial-mesenchymal transition by repressing FOXK1 in gastric cancer.
EPHA2 feedback activation limits the response to PDEδ inhibition in KRAS-dependent cancer cells.
A lncRNA coordinates with Ezh2 to inhibit HIF-1α transcription and suppress cancer cell adaption to hypoxia.
RBBP8/CtIP suppresses P21 expression by interacting with CtBP and BRCA1 in gastric cancer.
Comparative Transcriptome Analysis Reveals Different Host Cell Responses to Acute and Persistent Foot-and-Mouth Disease Virus Infection.
Histone deacetylase 6 inhibition restores autophagic flux to promote functional recovery after spinal cord injury.
Bisphenol A Exposure Enhances Endometrial Stromal Cell Invasion and Has a Positive Association with Peritoneal Endometriosis.
HSF1 promotes the viability of islet β-cells via upregulating SIRPα expression.
N-glycosylation of uterine endometrium determines its receptivity.
Protocatechuic Aldehyde Represses Proliferation and Migration of Breast Cancer Cells through Targeting C-terminal Binding Protein 1.
Chidamide induces necroptosis via regulation of c‑FLIPL expression in Jurkat and HUT‑78 cells.
miR‑337‑3p inhibits gastric tumor metastasis by targeting ARHGAP10.
HDAC11 promotes meiotic apparatus assembly during mouse oocyte maturation via decreasing H4K16 and α-tubulin acetylation.
α-synuclein promotes progression of Parkinson's disease by upregulating autophagy signaling pathway to activate NLRP3 inflammasome.
BMP4 induces asymmetric cell division in human glioma stem-like cells.
Maternal exposure to fine particle matters cause autophagy via UPR-mediated PI3K-mTOR pathway in testicular tissue of adult male mice in offspring.
Capping Protein Regulator and Myosin 1 Linker 3 Is Required for Tumor Metastasis.
3-Mercaptopyruvate sulfurtransferase supports endothelial cell angiogenesis and bioenergetics.
Retinoic acid receptor gamma is targeted by microRNA-124 and inhibits neurite outgrowth.
Proteomics profiling of epithelium-derived exosomes from nasal polyps revealed signaling functions affecting cellular proliferation.
Arfgef1 haploinsufficiency in mice alters neuronal endosome composition and decreases membrane surface postsynaptic GABA(A) receptors.
The role of invariant natural killer T cells in experimental xenobiotic-induced cholestatic hepatotoxicity.
lncRNA SNHG3 facilitates acute myeloid leukemia cell growth via the regulation of miR-758-3p/SRGN axis.
A risk prediction model of DNA methylation improves prognosis evaluation and indicates gene targets in prostate cancer.
Ubiquitination of NOTCH2 by DTX3 suppresses the proliferation and migration of human esophageal carcinoma.
3-O-Acetyl-11-keto- β -boswellic acid ameliorated aberrant metabolic landscape and inhibited autophagy in glioblastoma.
FAM172A inhibits EMT in pancreatic cancer via ERK-MAPK signaling.
Systematic Comparison of Label-Free, SILAC, and TMT Techniques to Study Early Adaption toward Inhibition of EGFR Signaling in the Colorectal Cancer Cell Line DiFi.
Extracellular nanofiber-orchestrated cytoskeletal reorganization and mediated directional migration of cancer cells.
DGCR8/ZFAT-AS1 Promotes CDX2 Transcription in a PRC2 Complex-Dependent Manner to Facilitate the Malignant Biological Behavior of Glioma Cells.
The Fluoro-Thiazolylhydrazone Compound TSC-3C Inhibits Triple Negative Breast Cancer (TNBC) Cell Line Activity by Promoting Apoptosis, Regulating the MAPK Pathway and Inducing Mitochondrial Dysfunction.
Protective properties of heme oxygenase-1 expressed in umbilical cord mesenchymal stem cells help restore the ovarian function of premature ovarian failure mice through activating the JNK/Bcl-2 signal pathway-regulated autophagy and upregulating the circulating of CD8(+)CD28(-) T cells.
A DNAH17 missense variant causes flagella destabilization and asthenozoospermia.
Mevalonate metabolism-dependent protein geranylgeranylation regulates thymocyte egress.
Differential effects of Chinese high-fat dietary habits on lipid metabolism: mechanisms and health implications.
Downregulation of lung miR-203a-3p expression by high-altitude hypoxia enhances VEGF/Notch signaling.
SOX2 Represses Hepatitis B Virus Replication by Binding to the Viral EnhII/Cp and Inhibiting the Promoter Activation.
FKBP9 promotes the malignant behavior of glioblastoma cells and confers resistance to endoplasmic reticulum stress inducers.
Assessment of Prolonged Dengue Virus Infection in Dermal Fibroblasts and Hair-Follicle Dermal Papilla Cells.
Anti-inflammatory effects of Lactobacillus johnsonii L531 in a pig model of Salmonella Infantis infection involves modulation of CCR6(+) T cell responses and ER stress.
The behavioural and neuropathologic sexual dimorphism and absence of MIP-3α in tau P301S mouse model of Alzheimer's disease.
Rumen-Protected Glucose Stimulates the Insulin-Like Growth Factor System and mTOR/AKT Pathway in the Endometrium of Early Postpartum Dairy Cows.
Structural Basis for Inhibiting Porcine Epidemic Diarrhea Virus Replication with the 3C-Like Protease Inhibitor GC376.
Modulation of in vitro Brain Endothelium by Mechanical Trauma: Structural and Functional Restoration by Poloxamer 188.
A Novel Role for PX, a Structural Protein of Fowl Adenovirus Serotype 4 (FAdV4), as an Apoptosis-Inducer in Leghorn Male Hepatocellular Cell.
Targeted overexpression of the long noncoding RNA ODSM can regulate osteoblast function in vitro and in vivo.
Generation of a self-cleaved inducible Cre recombinase for efficient temporal genetic manipulation.
Overcoming cisplatin resistance by targeting the MTDH-PTEN interaction in ovarian cancer with sera derived from rats exposed to Guizhi Fuling wan extract.
Dynasore potentiates c-Met inhibitors against hepatocellular carcinoma through destabilizing c-Met.
GRWD1 promotes cell proliferation and migration in non-small cell lung cancer by activating the Notch pathway.
Extracellular vesicles transmitted miR-31-5p promotes sorafenib resistance by targeting MLH1 in renal cell carcinoma.
Down-regulation of CCR7 via AKT pathway and GATA2 inactivation suppressed trophoblast migration and invasion in recurrent spontaneous abortion†.
Entorhinal cortex-based metabolic profiling of chronic restraint stress mice model of depression.
Level of N6-Methyladenosine in Peripheral Blood RNA: A Novel Predictive Biomarker for Gastric Cancer.
Sodium butyrate causes α-synuclein degradation by an Atg5-dependent and PI3K/Akt/mTOR-related autophagy pathway.
Nucleostemin promotes hepatocellular carcinoma by regulating the function of STAT3.
Silencing of DsbA-L gene impairs the PPARγ agonist function of improving insulin resistance in a high-glucose cell model.
Autotaxin stimulates LPA2 receptor in macrophages and exacerbates dextran sulfate sodium-induced acute colitis.
Neuron-derived factors negatively modulate ryanodine receptor-mediated calcium release in cultured mouse astrocytes.
Inhibition of PI3K/Akt/NF-κB signaling by Aloin for ameliorating the progression of osteoarthritis: In vitro and in vivo studies.
Protective effect of taraxasterol on ischemia/reperfusion-induced acute kidney injury via inhibition of oxidative stress, inflammation, and apoptosis.
Inhibition of PCSK9 potentiates immune checkpoint therapy for cancer.
Structure of LRRK2 in Parkinson's disease and model for microtubule interaction.
Hepatoprotective effects of Camellia nitidissima aqueous ethanol extract against CCl(4)-induced acute liver injury in SD rats related to Nrf2 and NF-κB signalling.
Hepatoprotective effect of Xiayuxue decoction ethyl acetate fraction against carbon tetrachloride-induced liver fibrosis in mice via inducing apoptosis and suppressing activation of hepatic stellate cells.
Hypermethylation-mediated silencing of NDRG4 promotes pancreatic ductal adenocarcinoma by regulating mitochondrial function.
Hypermethylation-mediated silencing of NDRG4 promotes pancreatic ductal adenocarcinoma by regulating mitochondrial function.
Anti-tumour activity of zinc ionophore pyrithione in human ovarian cancer cells through inhibition of proliferation and migration and promotion of lysosome-mitochondrial apoptosis.
Circ_0079593 facilitates proliferation, metastasis, glucose metabolism and inhibits apoptosis in melanoma by regulating the miR-516b/GRM3 axis.
Modulation of miRNAs by vitamin C in H2O2‑exposed human umbilical vein endothelial cells.
The protective effects of umbilical cord-derived endothelial colony forming cells on hepatic veno-occlusive disease.
Tumor cell-expressed IL-15Rα drives antagonistic effects on the progression and immune control of gastric cancer and is epigenetically regulated in EBV-positive gastric cancer.
Aberrant expression of miRNA-192-5p contributes to N,N-dimethylformamide-induced hepatic apoptosis.
Upregulated miR-101 inhibits acute kidney injury-chronic kidney disease transition by regulating epithelial-mesenchymal transition.
The kinesin motor protein KIF4A as a potential therapeutic target in renal cell carcinoma.
Promotion of esophageal adenocarcinoma metastasis via Wnt/ß-catenin signal pathway by sorting nexins 3.
Chondroitin synthase-3 regulates nucleus pulposus degeneration through actin-induced YAP signaling.
Polyphyllin I attenuates cognitive impairments and reduces AD-like pathology through CIP2A-PP2A signaling pathway in 3XTg-AD mice.
Cold-induced RNA-binding protein (CIRBP) regulates the expression of Src-associated during mitosis of 68 kDa (Sam68) and extracellular signal-regulated kinases (ERK) during heat stress-induced testicular injury.
JMY expression by Sertoli cells contributes to mediating spermatogenesis in mice.
Platelet-derived microvesicles promote endothelial progenitor cell proliferation in intimal injury by delivering TGF-β1.
Maresin1 Promotes M2 Macrophage Polarization Through Peroxisome Proliferator-Activated Receptor-γ Activation to Expedite Resolution of Acute Lung Injury.
Inhibition of porcine reproductive and respiratory syndrome virus by PKC inhibitor dequalinium chloride in vitro.
Long noncoding RNA XIST regulates cardiomyocyte apoptosis by targeting miR-873-5p/MCL1 axis.
IGFBP6 regulates vascular smooth muscle cell proliferation and morphology via cyclin E-CDK2.
The proinflammatory cytokines IL-1β and TNF-α modulate corneal epithelial wound healing through p16(Ink4a) suppressing STAT3 activity.
Sulforaphane suppresses polyinosinic‑polycytidylic acid‑stimulated release of cytokines, chemokines and MMPs by human corneal fibroblasts.
miR‑124‑3p regulates angiogenesis in peripheral arterial disease by targeting STAT3.
Demethylation of HACE1 gene promoter by propofol promotes autophagy of human A549 cells.
Long noncoding RNA HAND2-AS1 reduced the viability of hepatocellular carcinoma via targeting microRNA-300/SOCS5 axis.
UBR5 over-expression contributes to poor prognosis and tamoxifen resistance of ERa+ breast cancer by stabilizing β-catenin.
Loss of hepatic aldolase B activates Akt and promotes hepatocellular carcinogenesis by destabilizing the Aldob/Akt/PP2A protein complex.
A spirostanol saponin isolated from Tupistra chinensis Baker simultaneously induces apoptosis and autophagy by regulating the JNK pathway in human gastric cancer cells.
LGR4 maintains HGSOC cell epithelial phenotype and stem-like traits.
Pentraxin 3 contributes to neurogenesis after traumatic brain injury in mice.
Glycogen synthase kinase-3β inhibition alleviates activation of the NLRP3 inflammasome in myocardial infarction.
The role of invariant natural killer T cells and associated immunoregulatory factors in triptolide-induced cholestatic liver injury.
LINC00673 exerts oncogenic function in cervical cancer by negatively regulating miR-126-5p expression and activates PTEN/PI3K/AKT signaling pathway.
The effects of cytarabine combined with ginsenoside compound K synergistically induce DNA damage in acute myeloid leukemia cells.
Gu-Ben-Fang-Xiao attenuates allergic airway inflammation by inhibiting BAFF-mediated B cell activation.
Down-regulation of long noncoding RNA LINC00472 alleviates sepsis-induced acute hepatic injury by regulating miR-373-3p/TRIM8 axis.
Enterovirus 71 induces neural cell apoptosis and autophagy through promoting ACOX1 downregulation and ROS generation.
Down-regulation of lncRNA DNAJC3-AS1 inhibits colon cancer via regulating miR-214-3p/LIVIN axis.
Upregulation of the microRNA rno-miR-146b-5p may be involved in the development of intestinal injury through inhibition of Kruppel-like factor 4 in intestinal sepsis.
Cannabinoid receptor subtype influence on neuritogenesis in human SH-SY5Y cells.
Targeted degradation of CD147 proteins in melanoma.
Design, synthesis and biological evaluation of novel 1,3,4-thiadiazole derivatives as anti-glioblastoma agents targeting the AKT pathway.
Latcripin-7A, derivative of Lentinula edodes C(91-3), reduces migration and induces apoptosis, autophagy, and cell cycle arrest at G(1) phase in breast cancer cells.
Structural and Functional Characterization of Host FHL1 Protein Interaction with Hypervariable Domain of Chikungunya Virus nsP3 Protein.
β-Elemene enhances radiosensitivity in non-small-cell lung cancer by inhibiting epithelial-mesenchymal transition and cancer stem cell traits via Prx-1/NF-kB/iNOS signaling pathway.
FN-EDA mediates angiogenesis of hepatic fibrosis via integrin-VEGFR2 in a CD63 synergetic manner.
Dually regulating the proliferation and the immune microenvironment of melanoma via nanoparticle-delivered siRNA targeting onco-immunologic CD155.
Extracellular Cystatin F Is Internalised by Cytotoxic T Lymphocytes and Decreases Their Cytotoxicity.
The protective effect of 1,25(OH)(2)D(3) against cardiac hypertrophy is mediated by the cyclin-dependent kinase inhibitor p21.
miR-214 Attenuates Aortic Valve Calcification by Regulating Osteogenic Differentiation of Valvular Interstitial Cells.
YTHDF1 Facilitates the Progression of Hepatocellular Carcinoma by Promoting FZD5 mRNA Translation in an m6A-Dependent Manner.
circFN1 Mediates Sorafenib Resistance of Hepatocellular Carcinoma Cells by Sponging miR-1205 and Regulating E2F1 Expression.
Translatome and Transcriptome Profiling of Hypoxic-Induced Rat Cardiomyocytes.
SPOCK1/SIX1axis promotes breast cancer progression by activating AKT/mTOR signaling.
Exogenous hydrogen sulfide inhibits apoptosis by regulating endoplasmic reticulum stress-autophagy axis and improves myocardial reconstruction after acute myocardial infarction.
Overexpression of Mucin 1 Suppresses the Therapeutical Efficacy of Disulfiram against Canine Mammary Tumor.
Discovery and Biological Evaluation of CD147 N-Glycan Inhibitors: A New Direction in the Treatment of Tumor Metastasis.
Radiosensitization Effect of AGuIX, a Gadolinium-Based Nanoparticle, in Nonsmall Cell Lung Cancer.
Lanthanum chloride causes blood-brain barrier disruption through intracellular calcium-mediated RhoA/Rho kinase signaling and myosin light chain kinase.
Schistosoma mansoni eggs induce Wnt/β-catenin signaling and activate the protooncogene c-Jun in human and hamster colon.
CircPlekha7 plays an anti-fibrotic role in intrauterine adhesions by modulating endometrial stromal cell proliferation and apoptosis.
Rapalink-1 Targets Glioblastoma Stem Cells and Acts Synergistically with Tumor Treating Fields to Reduce Resistance against Temozolomide.
MELK is an oncogenic kinase essential for metastasis, mitotic progression, and programmed death in lung carcinoma.
LncRNA LINC00998 inhibits the malignant glioma phenotype via the CBX3-mediated c-Met/Akt/mTOR axis.
Variants in RABL2A causing male infertility and ciliopathy.
Aldehyde dehydrogenase 2 protects against sympathetic excitation-induced cardiac fibrosis.
Pharmacological activation of the p53 pathway by a new compound CYZ2017 exerts anti-tumor effects.
The deubiquitinase USP36 Regulates DNA replication stress and confers therapeutic resistance through PrimPol stabilization.
S119N Mutation of the E3 Ubiquitin Ligase SPOP Suppresses SLC7A1 Degradation to Regulate Hepatoblastoma Progression.
Exosome-mediated Hic-5 regulates proliferation and apoptosis of osteosarcoma via Wnt/β-catenin signal pathway.
Hugan Qingzhi medication ameliorates free fatty acid-induced L02 hepatocyte endoplasmic reticulum stress by regulating the activation of PKC-δ.
Epigenetic Inactivation of α-Internexin Accelerates Microtubule Polymerization in Colorectal Cancer.
Microtubule poleward flux in human cells is driven by the coordinated action of four kinesins.
FGF signaling regulates development by processes beyond canonical pathways.
Silencing of the lncRNA TUG1 attenuates the epithelial-mesenchymal transition of renal tubular epithelial cells by sponging miR-141-3p via regulating β-catenin.
iTRAQ-based proteomics implies inflammasome pathway activation in the prefrontal cortex of CSDS mice may influence resilience and susceptibility.
LncRNA Gm16410 regulates PM(2.5)-induced lung Endothelial-Mesenchymal Transition via the TGF-β1/Smad3/p-Smad3 pathway.
Inhibition of autophagy enhances cadmium-induced apoptosis in duck renal tubular epithelial cells.
Cadmium inhibits apoptosis of human esophageal epithelial cells by upregulating CDK6.
E3 ligase FBXW7 restricts M2-like tumor-associated macrophage polarization by targeting c-Myc.
Cigarette smoke extract induces airway epithelial cell death via repressing PRMT6/AKT signaling.
Stachydrine ameliorates the progression of intervertebral disc degeneration via the PI3K/Akt/NF-κB signaling pathway: in vitro and in vivo studies.
The induction and characterization of monoclonal antibodies specific to GP of Ebola virus.
The vulnerability of motor and frontal cortex-dependent behaviors in mice expressing ALS-linked mutation in TDP-43.
Differential Effects of Components in Artemisia annua Extract on the Induction of Drug-Metabolizing Enzyme Expression Mediated by Nuclear Receptors.
Rhein attenuates renal inflammatory injury of uric acid nephropathy via lincRNA-Cox2/miR-150-5p/STAT1 axis.
Melatonin alleviates intestinal injury, neuroinflammation and cognitive dysfunction caused by intestinal ischemia/reperfusion.
IL-38 alleviates the inflammatory response and the degeneration of nucleus pulposus cells via inhibition of the NF-κB signaling pathway in vitro.
Knockdown of interferon-induced transmembrane protein 1 inhibited proliferation, induced cell cycle arrest and apoptosis, and suppressed MAPK signaling pathway in pancreatic cancer cells.
To what extent should the intestinal be resected proximally after radiotherapy: hint from a pathological view.
Rationalized inhibition of mixed lineage kinase 3 and CD70 enhances life span and antitumor efficacy of CD8(+) T cells.
The role of miR-34c-5p/Notch in epithelial-mesenchymal transition (EMT) in endometriosis.
miR-296-5p suppresses stem cell potency of hepatocellular carcinoma cells via regulating Brg1/Sall4 axis.
m(6)A mRNA Methylation Controls Functional Maturation in Neonatal Murine β-Cells.
Metabolomic profiling reveals similar cytotoxic effects and protective functions of quercetin during deoxynivalenol- and 15-acetyl deoxynivalenol-induced cell apoptosis.
miR-410-5p promotes the development of diabetic cardiomyopathy by suppressing PIM1-induced anti-apoptosis.
Exosomes derived from human exfoliated deciduous teeth ameliorate adult bone loss in mice through promoting osteogenesis.
The AKR1B1 inhibitor epalrestat suppresses the progression of cervical cancer.
Neferine Inhibits Expression of Inflammatory Mediators and Matrix Degrading Enzymes in IL-1β-Treated Rat Chondrocytes via Suppressing MAPK and NF-κB Signaling Pathways.
Schisandrin B improves cerebral ischemia and reduces reperfusion injury in rats through TLR4/NF-κB signaling pathway inhibition.
Rare mutations in the autophagy-regulating gene AMBRA1 contribute to human neural tube defects.
Red nucleus IL-6 mediates the maintenance of neuropathic pain by inducing the productions of TNF-α and IL-1β through the JAK2/STAT3 and ERK signaling pathways.
Astragaloside IV attenuates chronic intermittent hypoxia-induced myocardial injury by modulating Ca(2+) homeostasis.
MiR-129-5p alleviates myocardial injury by targeting suppressor of cytokine signaling 2 after ischemia/reperfusion.
Effect of AmyTrap, an amyloid-β binding drug, on Aβ induced mitochondrial dysfunction and tau phosphorylation in cultured neuroblastoma cells.
Curcumin inhibits calcification of human aortic valve interstitial cells by interfering NF-κB, AKT, and ERK pathways.
Src-mediated phosphorylation of GAPDH regulates its nuclear localization and cellular response to DNA damage.
Hydrogen sulphide ameliorating skeletal muscle atrophy in db/db mice via Muscle RING finger 1 S-sulfhydration.
Effects of PYRIN-containing Apaf1-like protein 1 on isoflurane-induced postoperative cognitive dysfunction in aged rats.
Overexpression of negative regulator of ubiquitin-like proteins 1 (NUB1) inhibits proliferation and invasion of gastric cancer cells through upregulation of p27Kip1 and inhibition of epithelial-mesenchymal transition.
Cloning of the XPD gene and its function in malignant melanoma cells.
miR-140-3p enhances cisplatin sensitivity and attenuates stem cell-like properties through repressing Wnt/β-catenin signaling in lung adenocarcinoma cells.
ZMIZ1 promotes the proliferation and migration of melanocytes in vitiligo.
BX795 demonstrates potent antiviral benefits against herpes simplex Virus-1 infection of human cell lines.
miR-106a Regulates Cell Proliferation and Autophagy by Targeting LKB1 in HPV-16-Associated Cervical Cancer.
Targeting G6PD reverses paclitaxel resistance in ovarian cancer by suppressing GSTP1.
Celastrol ameliorates autoimmune disorders in Trex1-deficient mice.
Hippocampal glutamatergic synapses impairment mediated novel-object recognition dysfunction in rats with neuropathic pain.
Correcting abnormalities in miR-124/PTPN1 signaling rescues tau pathology in Alzheimer's disease.
Overexpression of PTEN regulated by miR-19b and miR-494 in the villous of recurrent spontaneous abortion patients.
Apocynum venetum leaf extract protects against H(2)O(2)-induced oxidative stress by increasing autophagy in PC12 cells.
Prunella vulgaris L. attenuates experimental autoimmune thyroiditis by inducing indoleamine 2,3-dioxygenase 1 expression and regulatory T cell expansion.
LINC00467 promotes cell proliferation and stemness in lung adenocarcinoma by sponging miR-4779 and miR-7978.
Glibenclamide restores dopaminergic reward circuitry in obese mice through interscauplar brown adipose tissue.
MiR-195 suppression alleviates apoptosis and oxidative stress in CCl4-induced ALI in mice by targeting Pim-1.
Sarcopenia is attenuated by TRB3 knockout in aging mice via the alleviation of atrophy and fibrosis of skeletal muscles.
The mechanism of Chinese herbal formula HQT in the treatment of rheumatoid arthritis is related to its regulation of lncRNA uc.477 and miR-19b.
MiR-221/222 promote migration and invasion, and inhibit autophagy and apoptosis by modulating ATG10 in aggressive papillary thyroid carcinoma.
METTL3 and N6-Methyladenosine Promote Homologous Recombination-Mediated Repair of DSBs by Modulating DNA-RNA Hybrid Accumulation.
Partial MHC/neuroantigen peptide constructs attenuate methamphetamine-seeking and brain chemokine (C-C motif) ligand 2 levels in rats.
Schisandrin ameliorates cognitive deficits, endoplasmic reticulum stress and neuroinflammation in streptozotocin (STZ)-induced Alzheimer's disease rats.
Butyrate-mediated autophagy inhibition limits cytosolic Salmonella Infantis replication in the colon of pigs treated with a mixture of Lactobacillus and Bacillus.
Neutrophil extracellular traps amplify neutrophil recruitment and inflammation in neutrophilic asthma by stimulating the airway epithelial cells to activate the TLR4/ NF-κB pathway and secrete chemokines.
Icotinib Attenuates Monocrotaline-Induced Pulmonary Hypertension by Preventing Pulmonary Arterial Smooth Muscle Cell Dysfunction.
Macrophage K63-Linked Ubiquitination of YAP Promotes Its Nuclear Localization and Exacerbates Atherosclerosis.
Nicotinamide Mononucleotide Supplementation Reverses the Declining Quality of Maternally Aged Oocytes.
miR-4634 augments the anti-tumor effects of RAD001 and associates well with clinical prognosis of non-small cell lung cancer.
An Optimized Reverse Genetics System Suitable for Efficient Recovery of Simian, Human, and Murine-Like Rotaviruses.
[Down-regulation of pannexin 2 channel enhances cisplatin-induced apoptosis in testicular cancer I-10 cells].
16-Hydroxycleroda-3,13-dien-15,16-olide Induces Apoptosis in Human Bladder Cancer Cells through Cell Cycle Arrest, Mitochondria ROS Overproduction, and Inactivation of EGFR-Related Signalling Pathways.
Promising xenograft animal model recapitulating the features of human pancreatic cancer.
Glutamyl-Prolyl-tRNA Synthetase Regulates Proline-Rich Pro-Fibrotic Protein Synthesis During Cardiac Fibrosis.
The HMGB1-2 Ovarian Cancer Interactome. The Role of HMGB Proteins and Their Interacting Partners MIEN1 and NOP53 in Ovary Cancer and Drug-Response.
Chidamide, a histone deacetylase inhibitor, inhibits autophagy and exhibits therapeutic implication in chronic lymphocytic leukemia.
The Circadian Hormone Melatonin Inhibits Morphine-Induced Tolerance and Inflammation via the Activation of Antioxidative Enzymes.
Small molecules targeting RORγt inhibit autoimmune disease by suppressing Th17 cell differentiation.
The gut microbiota regulates autism-like behavior by mediating vitamin B(6) homeostasis in EphB6-deficient mice.
In Vitro and In Vivo Activity, Tolerability, and Mechanism of Action of BX795 as an Antiviral against Herpes Simplex Virus 2 Genital Infection.
A kinase-independent function for AURORA-A in replisome assembly during DNA replication initiation.
A CRISPR knockout negative screen reveals synergy between CDKs inhibitor and metformin in the treatment of human cancer in vitro and in vivo.
Exosomal Delivery of AntagomiRs Targeting Viral and Cellular MicroRNAs Synergistically Inhibits Cancer Angiogenesis.
Antidepressant-like Effect of Merazin Hydrate Depends on NO/ERK by Suppressing Its Downstream NF-κB or Nonactivating CREB/BDNF in Mouse Hippocampus.
Ubiquitin-Conjugating Enzyme 2S Enhances Viral Replication by Inhibiting Type I IFN Production through Recruiting USP15 to Deubiquitinate TBK1.
Novel dot-blot assay for detection of vascular Notch3 aggregates in patients with CADASIL.
Lamin B2 promotes the malignant phenotype of non-small cell lung cancer cells by upregulating dimethylation of histone 3 lysine 9.
Lactobacillus johnsonii L531 Ameliorates Escherichia coli-Induced Cell Damage via Inhibiting NLRP3 Inflammasome Activity and Promoting ATG5/ATG16L1-Mediated Autophagy in Porcine Mammary Epithelial Cells.
Magnetic targeting enhances the cutaneous wound healing effects of human mesenchymal stem cell-derived iron oxide exosomes.
TRIM59 attenuates IL-1β-driven cartilage matrix degradation in osteoarthritis via direct suppression of NF-κB and JAK2/STAT3 signaling pathway.
A cell-based high-throughput screen identifies drugs that cause bleeding disorders by off-targeting the vitamin K cycle.
Flavagline synthetic derivative induces senescence in glioblastoma cancer cells without being toxic to healthy astrocytes.
Acetylation of Cytidine Residues Boosts HIV-1 Gene Expression by Increasing Viral RNA Stability.
Amyloid precursor protein glycosylation is altered in the brain of patients with Alzheimer's disease.
Expressional Localization and Functionally Identifying an RNA Editing Enzyme BmADARa of the Silkworm Bombyx mori.
Qingda granule inhibits angiotensin Ⅱ induced VSMCs proliferation through MAPK and PI3K/AKT pathways.
Frequent and mild scrotal heat stress in mice epigenetically alters glucose metabolism in the male offspring.
Dual-specificity phosphatase 29 is induced during neurogenic skeletal muscle atrophy and attenuates glucocorticoid receptor activity in muscle cell culture.
Chlorogenic acid attenuates cyclophosphamide-induced rat interstitial cystitis.
Syndecan-1 regulates extracellular matrix expression in keloid fibroblasts via TGF-β1/Smad and MAPK signaling pathways.
Dandelion Extract Alleviated Lipopolysaccharide-Induced Oxidative Stress through the Nrf2 Pathway in Bovine Mammary Epithelial Cells.
MicroRNA-378-3p/5p suppresses the migration and invasiveness of oral squamous carcinoma cells by inhibiting KLK4 expression.
Anethole compromises human sperm function by affecting the sperm intracellular calcium concentration and tyrosine phosphorylation.
miR-455-3p enhances chondrocytes apoptosis and inflammation by targeting COL2A1 in the in vitro osteoarthritis model.
Glaucocalyxin A alleviates LPS-mediated septic shock and inflammation via inhibiting NLRP3 inflammasome activation.
Baicalin attenuates hepatic injury in non-alcoholic steatohepatitis cell model by suppressing inflammasome-dependent GSDMD-mediated cell pyroptosis.
Cellular secretion and cytotoxicity of transthyretin mutant proteins underlie late-onset amyloidosis and neurodegeneration.
Synergistic effects of tanshinone IIA and andrographolide on the apoptosis of cancer cells via crosstalk between p53 and reactive oxygen species pathways.
Streptococcus pneumoniae aminopeptidase N contributes to bacterial virulence and elicits a strong innate immune response through MAPK and PI3K/AKT signaling.
E6‑regulated overproduction of prostaglandin E2 may inhibit migration of dendritic cells in human papillomavirus 16‑positive cervical lesions.
Effects of rutin on the oxidative stress, proliferation and osteogenic differentiation of periodontal ligament stem cells in LPS-induced inflammatory environment and the underlying mechanism.
Long noncoding RNA MACC1-AS1 promotes the stemness of hepatocellular carcinoma cells by antagonizing miR-145.
LncRNA MIAT/miR-133a-3p axis regulates atrial fibrillation and atrial fibrillation-induced myocardial fibrosis.
Low-intensity pulsed ultrasound promotes the expression of immediate-early genes in mouse ST2 bone marrow stromal cells.
Down-regulation of lncRNA BLACAT1 inhibits ovarian cancer progression by suppressing the Wnt/β-catenin signaling pathway via regulating miR-519d-3p.
Rab22a is a novel prognostic marker for cell progression in breast cancer.
Sirtuin 2 Inhibition Attenuates Sevoflurane-Induced Learning and Memory Deficits in Developing Rats via Modulating Microglial Activation.
CFIm25-regulated lncRNA acv3UTR promotes gastric tumorigenesis via miR-590-5p/YAP1 axis.
MiR-194-5p inhibited metastasis and EMT of nephroblastoma cells through targeting Crk.
MTH1 Inhibitor TH287 Suppresses Gastric Cancer Development Through the Regulation of PI3K/AKT Signaling.
Regulation of hepatic glutamine metabolism by miR-122.
Different Serotypes of Adeno-Associated Virus Vector- and Lentivirus-Mediated Tropism in Choroid Plexus by Intracerebroventricular Delivery.
Nicotinamide riboside rescues angiotensin II-induced cerebral small vessel disease in mice.
Estrogen accelerates heart regeneration by promoting the inflammatory response in zebrafish.
Potent USP10/13 antagonist spautin-1 suppresses melanoma growth via ROS-mediated DNA damage and exhibits synergy with cisplatin.
METTL3/YTHDF2 m(6) A axis promotes tumorigenesis by degrading SETD7 and KLF4 mRNAs in bladder cancer.
MiR-210-3p-EphrinA3-PI3K/AKT axis regulates the progression of oral cancer.
Long noncoding RNA FBXL19-AS1 induces tumor growth and metastasis by sponging miR-203a-3p in lung adenocarcinoma.
Estradiol-17β regulates proliferation and apoptosis of sheep endometrial epithelial cells by regulating the relative abundance of YAP1.
Long non‑coding RNA MALAT1 regulates cholesterol accumulation in ox‑LDL‑induced macrophages via the microRNA‑17‑5p/ABCA1 axis.
C9orf72 associates with inactive Rag GTPases and regulates mTORC1-mediated autophagosomal and lysosomal biogenesis.
Effects of propofol on LC3II and mTOR/p-mTOR expression during ischemia-reperfusion myocardium injury in rats with type 2 diabetes mellitus.
Galantamine Inhibits Aβ(1-42)-Induced Neurotoxicity by Enhancing α7nAChR Expression as a Cargo Carrier for LC3 Binding and Aβ(1-42) Engulfment During Autophagic Degradation.
Ehrlichia chaffeensis TRP120-mediated ubiquitination and proteasomal degradation of tumor suppressor FBW7 increases oncoprotein stability and promotes infection.
Potential role of full-length and nonfull-length progranulin in affecting aortic valve calcification.
Overcoming acquired resistance of EGFR-mutant NSCLC cells to the third generation EGFR inhibitor, osimertinib, with the natural product honokiol.
3,4,5-Tri-O-caffeoylquinic acid methyl ester isolated from Lonicera japonica Thunb. Flower buds facilitates hepatitis B virus replication in HepG2.2.15 cells.
Photobiomodulation by diffusing optical fiber on spinal cord: A feasibility study in piglet model.
Tissue Transglutaminase contributes to myelin phagocytosis in interleukin-4-treated human monocyte-derived macrophages.
Prazosin inhibits the proliferation and survival of acute myeloid leukaemia cells through down-regulating TNS1.
Circ-IGF1R inhibits cell invasion and migration in non-small cell lung cancer.
Low-dose lithium feeding increases the SERCA2a-to-phospholamban ratio, improving SERCA function in murine left ventricles.
Dexmedetomidine alleviates postoperative cognitive dysfunction through circular RNA in aged rats.
Small Nucleolar RNA, C/D Box 16 (SNORD16) Acts as a Potential Prognostic Biomarker in Colon Cancer.
PGN and LTA from Staphylococcus aureus Induced Inflammation and Decreased Lactation through Regulating DNA Methylation and Histone H3 Acetylation in Bovine Mammary Epithelial Cells.
Caspase-8 Induces Lysosome-Associated Cell Death in Cancer Cells.
Type 3 adenylyl cyclase in the MOE is involved in learning and memory in mice.
α-Tubulin detyrosination impairs mitotic error correction by suppressing MCAK centromeric activity.
Impaired autophagic flux contributes to muscle atrophy in obesity by affecting muscle degradation and regeneration.
The cellular expression and proteolytic processing of the amyloid precursor protein is independent of TDP-43.
METTL3 is essential for postnatal development of brown adipose tissue and energy expenditure in mice.
Breast cancer-derived exosomes transmit lncRNA SNHG16 to induce CD73+γδ1 Treg cells.
Dimethyl itaconate, an itaconate derivative, exhibits immunomodulatory effects on neuroinflammation in experimental autoimmune encephalomyelitis.
ACE2 correlated with immune infiltration serves as a prognostic biomarker in endometrial carcinoma and renal papillary cell carcinoma: implication for COVID-19.
PENK inhibits osteosarcoma cell migration by activating the PI3K/Akt signaling pathway.
Inhibition of cGAS-Mediated Interferon Response Facilitates Transgene Expression.
4,5-di-O-caffeoylquinic acid methyl ester isolated from Lonicera japonica Thunb. targets the Keap1/Nrf2 pathway to attenuate H(2)O(2)-induced liver oxidative damage in HepG2 cells.
Pathogenic Variants in CEP85L Cause Sporadic and Familial Posterior Predominant Lissencephaly.
The potential role of Krüppel-like factor 13 (Aj-klf13) in the intestine regeneration of sea cucumber Apostichopus japonicus.
Carnosol inhibits inflammasome activation by directly targeting HSP90 to treat inflammasome-mediated diseases.
Sitagliptin Inhibits Extracellular Matrix Accumulation and Proliferation in Lung Fibroblasts.
Alamandine attenuates hepatic fibrosis by regulating autophagy induced by NOX4-dependent ROS.
Reverse Genetics Reveals a Role of Rotavirus VP3 Phosphodiesterase Activity in Inhibiting RNase L Signaling and Contributing to Intestinal Viral Replication In Vivo.
Induced CD10 expression during monocyte-to-macrophage differentiation identifies a unique subset of macrophages in pancreatic ductal adenocarcinoma.
Zhx2 Accelerates Sepsis by Promoting Macrophage Glycolysis via Pfkfb3.
NOD1 Promotes Antiviral Signaling by Binding Viral RNA and Regulating the Interaction of MDA5 and MAVS.
The circular RNA CDR1as regulate cell proliferation via TMED2 and TMED10.
Betulinic Acid-Mediated Tuning of PERK/CHOP Signaling by Sp1 Inhibition as a Novel Therapeutic Strategy for Glioblastoma.
Interleukin 26 Skews Macrophage Polarization Towards M1 Phenotype by Activating cJUN and the NF-κB Pathway.
Doxorubicin-polyglycerol-nanodiamond conjugates disrupt STAT3/IL-6-mediated reciprocal activation loop between glioblastoma cells and astrocytes.
A Novel Rhynchophylline Analog, Y396, Inhibits Endothelial Dysfunction Induced by Oxidative Stress in Diabetes Through Epidermal Growth Factor Receptor.
The HIV-1 capsid-binding host factor CPSF6 is post-transcriptionally regulated by the cellular microRNA miR-125b.
Paraoxonase 3 functions as a chaperone to decrease functional expression of the epithelial sodium channel.
FTO promotes cell proliferation and migration in esophageal squamous cell carcinoma through up-regulation of MMP13.
Adipose-derived exosomes protect the pulmonary endothelial barrier in ventilator-induced lung injury by inhibiting the TRPV4/Ca(2+) signaling pathway.
miR-524-5p inhibits angiogenesis through targeting WNK1 in colon cancer cells.
OTUD1 Negatively Regulates Type I IFN Induction by Disrupting Noncanonical Ubiquitination of IRF3.
Lanthanum chloride impairs spatial learning and memory by inducing [Ca(2+)](m) overload, mitochondrial fission-fusion disorder and excessive mitophagy in hippocampal nerve cells of rats.
The protective effects of β-sitosterol and vermicularin from Thamnolia vermicularis (Sw.) Ach. against skin aging in vitro.
Tumor-associated macrophages (TAMs) depend on Shp2 for their anti-tumor roles in colorectal cancer.
Progerin accumulation in nucleus pulposus cells impairs mitochondrial function and induces intervertebral disc degeneration and therapeutic effects of sulforaphane.
Overexpression of MEF2D contributes to oncogenic malignancy and chemotherapeutic resistance in ovarian carcinoma.
Changes in the intestinal microecology induced by bacillus subtilis inhibit the occurrence of ulcerative colitis and associated cancers: a study on the mechanisms.
Collaborative ISL1/GATA3 interaction in controlling neuroblastoma oncogenic pathways overlapping with but distinct from MYCN.
CACYBP Enhances Cytoplasmic Retention of P27(Kip1) to Promote Hepatocellular Carcinoma Progression in the Absence of RNF41 Mediated Degradation.
Inhibition of SMYD2 suppresses tumor progression by down-regulating microRNA-125b and attenuates multi-drug resistance in renal cell carcinoma.
A Compound AC1Q3QWB Selectively Disrupts HOTAIR-Mediated Recruitment of PRC2 and Enhances Cancer Therapy of DZNep.
Autophagy impairment contributes to PBDE-47-induced developmental neurotoxicity and its relationship with apoptosis.
Long noncoding RNA GAS5 inhibits metastasis by targeting miR-182/ANGPTL1 in hepatocellular carcinoma.
CRISPRa-mediated FOXP3 gene upregulation in mammalian cells.
Aurora-A Induces Chemoresistance Through Activation of the AKT/mTOR Pathway in Endometrial Cancer.
Antitumor Effects of Berberine on Gliomas via Inactivation of Caspase-1-Mediated IL-1β and IL-18 Release.
A Novel Citrullinated Modification of Histone 3 and Its Regulatory Mechanisms Related to IPO-38 Antibody-Labeled Protein.
Nociceptin Receptor Is Overexpressed in Non-small Cell Lung Cancer and Predicts Poor Prognosis.
Identification of a Two-Gene (PML-EPB41) Signature With Independent Prognostic Value in Osteosarcoma.
PA28α/β Promote Breast Cancer Cell Invasion and Metastasis via Down-Regulation of CDK15.
Long Non-coding RNA SNHG12 Functions as a Competing Endogenous RNA to Regulate MDM4 Expression by Sponging miR-129-5p in Clear Cell Renal Cell Carcinoma.
The Tumor Suppressor Role of Zinc Finger Protein 671 (ZNF671) in Multiple Tumors Based on Cancer Single-Cell Sequencing.
MRPS30-DT Knockdown Inhibits Breast Cancer Progression by Targeting Jab1/Cops5.
FA2H Exhibits Tumor Suppressive Roles on Breast Cancers via Cancer Stemness Control.
SEMA3C Promotes Cervical Cancer Growth and Is Associated With Poor Prognosis.
Heatstroke-induced hepatocyte exosomes promote liver injury by activating the NOD-like receptor signaling pathway in mice.
Structural basis for the recognition of K48-linked Ub chain by proteasomal receptor Rpn13.
Loss of the Golgi Matrix Protein 130 Cause Aberrant IgA1 Glycosylation in IgA Nephropathy.
Hsa_circ_001569 is an unfavorable prognostic factor and promotes cell proliferation and metastasis by modulating PI3K-AKT pathway in breast cancer.
Long noncoding RNA glutathione peroxidase 3-antisense inhibits lens epithelial cell apoptosis by upregulating glutathione peroxidase 3 expression in age-related cataract.
The long noncoding RNA LINC00483 promotes lung adenocarcinoma progression by sponging miR-204-3p.
Effect of MicroRNA-20a on Osteogenic Differentiation of Human Adipose Tissue-Derived Stem Cells.
Xiaokeping Mixture Attenuates Diabetic Kidney Disease by Modulating TGF-β/Smad Pathway in db/db Mice.
Mangiferin Prevents TBHP-Induced Apoptosis and ECM Degradation in Mouse Osteoarthritic Chondrocytes via Restoring Autophagy and Ameliorates Murine Osteoarthritis.
A Peptide Analogue of Selectin Ligands Attenuated Atherosclerosis by Inhibiting Monocyte Activation.
Modulations of Histone Deacetylase 2 Offer a Protective Effect through the Mitochondrial Apoptosis Pathway in Acute Liver Failure.
Therapeutic Effects of Human Urine-Derived Stem Cells in a Rat Model of Cisplatin-Induced Acute Kidney Injury In Vivo and In Vitro.
Targeting INHBA in Ovarian Cancer Cells Suppresses Cancer Xenograft Growth by Attenuating Stromal Fibroblast Activation.
Abnormal Ribosome Biogenesis Partly Induced p53-Dependent Aortic Medial Smooth Muscle Cell Apoptosis and Oxidative Stress.
Pretreatment with AM1241 Enhances the Analgesic Effect of Intrathecally Administrated Mesenchymal Stem Cells.
Effect of YAP on an Immortalized Periodontal Ligament Stem Cell Line.
Bufei Qingyu Granules Inhibit the Development of Systemic Sclerosis via Notch-1/Jagged-2 Signaling Pathway.
Melatonin Rescued Reactive Oxygen Species-Impaired Osteogenesis of Human Bone Marrow Mesenchymal Stem Cells in the Presence of Tumor Necrosis Factor-Alpha.
Hepatitis B Virus X Protein-Induced RORγ Expression to Promote the Migration and Proliferation of Hepatocellular Carcinoma.
Identification of Upregulated HNRNPs Associated with Poor Prognosis in Pancreatic Cancer.
N-Acetylcysteine Attenuates Cisplatin-Induced Acute Kidney Injury by Inhibiting the C5a Receptor.
NANOG Attenuates Hair Follicle-Derived Mesenchymal Stem Cell Senescence by Upregulating PBX1 and Activating AKT Signaling.
Cul4a as a New Interaction Protein of PARP1 Inhibits Oxidative Stress-Induced H9c2 Cell Apoptosis.
Bu Shen Zhu Yun Decoction Improves Endometrial Receptivity via VEGFR-2-Mediated Angiogenesis.
Loss of SDC1 Expression Is Associated with Poor Prognosis of Colorectal Cancer Patients in Northern China.
Genetically Modified Porcine Mesenchymal Stem Cells by Lentiviral Tbx18 Create a Biological Pacemaker.
Protocatechuic Acid-Mediated miR-219a-5p Activation Inhibits the p66shc Oxidant Pathway to Alleviate Alcoholic Liver Injury.
Upregulation of UCP2 Expression Protects against LPS-Induced Oxidative Stress and Apoptosis in Cardiomyocytes.
Identification of CTRP1 as a Prognostic Biomarker and Oncogene in Human Glioblastoma.
A regulatory circuit of circ-MTO1/miR-17/QKI-5 inhibits the proliferation of lung adenocarcinoma.
Long non-coding RNA ARAP1-AS1 promotes the progression of bladder cancer by regulating miR-4735-3p/NOTCH2 axis.
The m(6)A eraser FTO facilitates proliferation and migration of human cervical cancer cells.
The long noncoding RNA PCGEM1 promotes cell proliferation, migration and invasion via targeting the miR-182/FBXW11 axis in cervical cancer.
LncRNA DANCR promotes the proliferation, migration, and invasion of tongue squamous cell carcinoma cells through miR-135a-5p/KLF8 axis.
Strand-specific miR-28-3p and miR-28-5p have differential effects on nasopharyngeal cancer cells proliferation, apoptosis, migration and invasion.
Methods for Monitoring Autophagy in Silkworm Organs.
MicroRNA-29a is a key regulon that regulates BRD4 and mitigates liver fibrosis in mice by inhibiting hepatic stellate cell activation.
LncRNA SNHG6 promotes proliferation, invasion and migration in colorectal cancer cells by activating TGF-β/Smad signaling pathway via targeting UPF1 and inducing EMT via regulation of ZEB1.
Ccr7 null mice are protected against diet-induced obesity via Ucp1 upregulation and enhanced energy expenditure.
Hypericin maintians PDX1 expression via the Erk pathway and protects islet β-cells against glucotoxicity and lipotoxicity.
KLF4-Mediated CDH3 Upregulation Suppresses Human Hepatoma Cell Growth and Migration via GSK-3β Signaling.
Taurine Transporter Regulates Adipogenic Differentiation of Human Adipose-Derived Stem Cells through Affecting Wnt/β-catenin Signaling Pathway.
Upregulated MMP28 in Hepatocellular Carcinoma Promotes Metastasis via Notch3 Signaling and Predicts Unfavorable Prognosis.
Inhibition of Heme Oxygenase-1 enhances hyperthermia-induced autophagy and antiviral effect.
MiR-93 regulates vascular smooth muscle cell proliferation, and neointimal formation through targeting Mfn2.
Muscle Injury Associated Elevated Oxidative Stress and Abnormal Myogenesis in Patients with Idiopathic Scoliosis.
Resveratrol induced premature senescence and inhibited epithelial-mesenchymal transition of cancer cells via induction of tumor suppressor Rad9.
Progranulin deficiency leads to reduced glucocerebrosidase activity.
Radiotherapy resistance acquisition in Glioblastoma. Role of SOCS1 and SOCS3.
P16 methylation increases the sensitivity of cancer cells to the CDK4/6 inhibitor palbociclib.
Porous Se@SiO(2) nanospheres attenuate ischemia/reperfusion (I/R)-induced acute kidney injury (AKI) and inflammation by antioxidative stress.
Long-Term Effects of Zinc Deficiency and Zinc Supplementation on Developmental Seizure-Induced Brain Damage and the Underlying GPR39/ZnT-3 and MBP Expression in the Hippocampus.
Effects of Acupuncture on Behavioral Stereotypies and Brain Dopamine System in Mice as a Model of Tourette Syndrome.
Calsyntenin-1 Negatively Regulates ICAM5 Accumulation in Postsynaptic Membrane and Influences Dendritic Spine Maturation in a Mouse Model of Fragile X Syndrome.
Osteoprotegerin promotes islet β cell proliferation in intrauterine growth retardation rats through the PI3K/AKT/FoxO1 pathway.
CD147 promotes cervical cancer migration and invasion by up-regulating fatty acid synthase expression.
CLK3 Is A Direct Target Of miR-144 And Contributes To Aggressive Progression In Hepatocellular Carcinoma.
Downregulation of CENPK suppresses hepatocellular carcinoma malignant progression through regulating YAP1.
INPP4B As A Prognostic And Diagnostic Marker Regulates Cell Growth Of Pancreatic Cancer Via Activating AKT.
GADD45a Mediated Cell Cycle Inhibition Is Regulated By P53 In Bladder Cancer.
MicroRNA-217 acts as a tumor suppressor and correlates with the chemoresistance of cervical carcinoma to cisplatin.
GJB4 promotes gastric cancer cell proliferation and migration via Wnt/CTNNB1 pathway.
GPX2 suppression of H(2)O(2) stress regulates cervical cancer metastasis and apoptosis via activation of the β-catenin-WNT pathway.
tRNA-derived fragment tRF-03357 promotes cell proliferation, migration and invasion in high-grade serous ovarian cancer.
14-Deoxycoleon U-induced endoplasmic reticulum stress-mediated apoptosis, autophagy, and cell cycle arrest in lung adenocarcinoma.
Diallyl disulfide inhibits colon cancer metastasis by suppressing Rac1-mediated epithelial-mesenchymal transition.
LncRNA FENDRR attenuates colon cancer progression by repression of SOX4 protein.
Exosomal Tenascin-c induces proliferation and invasion of pancreatic cancer cells by WNT signaling.
Silencing UBE4B induces nasopharyngeal carcinoma apoptosis through the activation of caspase3 and p53.
AdipoRon Alleviates Free Fatty Acid-Induced Myocardial Cell Injury Via Suppressing Nlrp3 Inflammasome Activation.
RRAD suppresses the Warburg effect by downregulating ACTG1 in hepatocellular carcinoma.
Upregulation of STC2 in colorectal cancer and its clinicopathological significance.
Oncogenic Role and Prognostic Value of MicroRNA-937-3p in Patients with Breast Cancer.
Osteoglycin (OGN) Inhibits Cell Proliferation and Invasiveness in Breast Cancer via PI3K/Akt/mTOR Signaling Pathway.
Overexpressing CCT6A Contributes To Cancer Cell Growth By Affecting The G1-To-S Phase Transition And Predicts A Negative Prognosis In Hepatocellular Carcinoma.
miR-140-3p Suppresses Cell Growth And Induces Apoptosis In Colorectal Cancer By Targeting PD-L1.
Osteopontin Mediates Cetuximab Resistance via the MAPK Pathway in NSCLC Cells.
Long noncoding RNA CASC15 predicts unfavorable prognosis and exerts oncogenic functions in non-small cell lung cancer.
MiR-27a-regulated FOXO1 promotes pancreatic ductal adenocarcinoma cell progression by enhancing Wnt/β-catenin signaling activity.
Low-molecular-weight fucoidan attenuates bleomycin-induced pulmonary fibrosis: possible role in inhibiting TGF-β1-induced epithelial-mesenchymal transition through ERK pathway.
Vitamin D retards intervertebral disc degeneration through inactivation of the NF-κB pathway in mice.
Herbacetin treatment remitted LPS induced inhibition of osteoblast differentiation through blocking AKT/NF-κB signaling pathway.
BPTF cooperates with p50 NF-κB to promote COX-2 expression and tumor cell growth in lung cancer.
Protective effects of Ulinastatin on oxidative stress and inflammation of rat-derived cardiomyocytes H9c2.
A pilot study comparing the genetic molecular biology of gestational and non-gestational choriocarcinoma.
HnRNP-F promotes cell proliferation by regulating TPX2 in bladder cancer.
UBE2T promotes proliferation via G2/M checkpoint in hepatocellular carcinoma.
Overexpression of HOXC6 promotes cell proliferation and migration via MAPK signaling and predicts a poor prognosis in glioblastoma.
Upregulation of family with sequence similarity 83 member D expression enhances cell proliferation and motility via activation of Wnt/β-catenin signaling and predicts poor prognosis in gastric cancer.
The β-galactoside α2,6-sialyltranferase 1 (ST6GAL1) inhibits the colorectal cancer metastasis by stabilizing intercellular adhesion molecule-1 via sialylation.
siPRDX2-elevated DNM3 inhibits the proliferation and metastasis of colon cancer cells via AKT signaling pathway.
Candidate tumor suppressor gene IRF6 is involved in human breast cancer pathogenesis via modulating PI3K-regulatory subunit PIK3R2 expression.
Dl-3-n-Butylphthalide Exerts Dopaminergic Neuroprotection Through Inhibition of Neuroinflammation.
UNBS5162 and amonafide inhibits tumor progression in human melanoma by the AKT/mTOR pathway.
The oncogenic role of GNL3 in the progression and metastasis of osteosarcoma.
Peptide V3 Inhibits the Growth of Human Hepatocellular Carcinoma by Inhibiting the Ras/Raf/MEK/ERK Signaling Pathway.
Lyn Kinase Promotes the Proliferation of Malignant Melanoma Cells through Inhibition of Apoptosis and Autophagy via the PI3K/Akt Signaling Pathway.
High expression of calreticulin indicates poor prognosis and modulates cell migration and invasion via activating Stat3 in nasopharyngeal carcinoma.
The Role of the Tumor Microenvironment in Neuropilin 1-Induced Radiation Resistance in Lung Cancer Cells.
KIAA0101 is a novel transcriptional target of FoxM1 and is involved in the regulation of hepatocellular carcinoma microvascular invasion by regulating epithelial-mesenchymal transition.
Association of SMUG1 SNPs in Intron Region and Linkage Disequilibrium with Occurrence of Cervical Carcinoma and HPV Infection in Chinese Population.
PINK1/Parkin-Mediated Mitophagy Regulation by Reactive Oxygen Species Alleviates Rocaglamide A-Induced Apoptosis in Pancreatic Cancer Cells.
MicroRNA-532-3p Suppresses Malignant Behaviors of Tongue Squamous Cell Carcinoma via Regulating CCR7.
ANLN and KDR Are Jointly Prognostic of Breast Cancer Survival and Can Be Modulated for Triple Negative Breast Cancer Control.
FKN Facilitates HK-2 Cell EMT and Tubulointerstitial Lesions via the Wnt/β-Catenin Pathway in a Murine Model of Lupus Nephritis.
Emodin Induced SREBP1-Dependent and SREBP1-Independent Apoptosis in Hepatocellular Carcinoma Cells.
Myricetin Attenuated Diabetes-Associated Kidney Injuries and Dysfunction via Regulating Nuclear Factor (Erythroid Derived 2)-Like 2 and Nuclear Factor-κB Signaling.
A Novel α-Galactosidase A Splicing Mutation Predisposes to Fabry Disease.
Sex Dependent Dysregulation of Hepatic Glucose Production in Lean Type 2 Diabetic Rats.
DNA Sensor IFI204 Contributes to Host Defense Against Staphylococcus aureus Infection in Mice.
Mechanosensitive Ion Channel Piezo1 Regulates Diet-Induced Adipose Inflammation and Systemic Insulin Resistance.
Phosphorylation of Microtubule- Associated Protein 4 Promotes Hypoxic Endothelial Cell Migration and Proliferation.
Transient Inhibition of mTORC1 Signaling Ameliorates Irradiation-Induced Liver Damage.
DDX23, an Evolutionary Conserved dsRNA Sensor, Participates in Innate Antiviral Responses by Pairing With TRIF or MAVS.
Structural and Functional Characterization of Hermetia illucens Larval Midgut.
Antiproliferative and Immunoregulatory Effects of Azelaic Acid Against Acute Myeloid Leukemia via the Activation of Notch Signaling Pathway.
Huang-Lian-Jie-Du Decoction Ameliorates Acute Ulcerative Colitis in Mice via Regulating NF-κB and Nrf2 Signaling Pathways and Enhancing Intestinal Barrier Function.
Muscle-Specific Sensitivity to Voluntary Physical Activity and Detraining.
USP37 Promotes Lung Cancer Cell Migration by Stabilizing Snail Protein via Deubiquitination.
Seneca Valley Virus 2C and 3C(pro) Induce Apoptosis via Mitochondrion-Mediated Intrinsic Pathway.
Parental Renovascular Hypertension-Induced Autonomic Dysfunction in Male Offspring Is Improved by Prenatal or Postnatal Treatment With Hydrogen Sulfide.
Severe Fever With Thrombocytopenia Syndrome Virus-Induced Macrophage Differentiation Is Regulated by miR-146.
The Therapeutic Effects of Treadmill Exercise on Osteoarthritis in Rats by Inhibiting the HDAC3/NF-KappaB Pathway in vivo and in vitro.
Protective Effects of Dioscin Against Doxorubicin-Induced Hepatotoxicity Via Regulation of Sirt1/FOXO1/NF-κb Signal.
Apigenin Inhibits IL-6 Transcription and Suppresses Esophageal Carcinogenesis.
Decreased NDRG1 expression is associated with pregnancy loss in mice and attenuates the in vitro decidualization of endometrial stromal cells.
Knockdown of SP1/Syncytin1 axis inhibits the proliferation and metastasis through the AKT and ERK1/2 signaling pathways in non-small cell lung cancer.
HOXA10 induces BCL2 expression, inhibits apoptosis, and promotes cell proliferation in gastric cancer.
Telbivudine antagonizes TLR4 to inhibit the epithelial-to-mesenchymal transition in human proximal tubular epithelial cells in vitro.
Functional evaluation of a novel GLA causative mutation in Fabry disease.
Cholesterol transport through the peroxisome-ER membrane contacts tethered by PI(4,5)P(2) and extended synaptotagmins.
The interaction between PLEKHG2 and ABL1 suppresses cell growth via the NF-κB signaling pathway in HEK293 cells.
Seneca Valley virus 2C and 3C inhibit type I interferon production by inducing the degradation of RIG-I.
Overexpression of matrix metalloproteinase-9 in breast cancer cell lines remarkably increases the cell malignancy largely via activation of transforming growth factor beta/SMAD signalling.
Essential role of IκB(NS) for in vivo CD4(+) T-cell activation, proliferation, and Th1-cell differentiation during Listeria monocytogenes infection in mice.
Transforming growth factor β1 promotes fibroblast-like synoviocytes migration and invasion via TGF-β1/Smad signaling in rheumatoid arthritis.
MiR-212-3p inhibits cell proliferation and promotes apoptosis by targeting nuclear factor IA in bladder cancer.
Hypoxia‑induced mitochondrial translocation of DNM1L increases mitochondrial fission and triggers mPTP opening in HCC cells via activation of HK2.
Ubiquitin ligase TRIM65 promotes colorectal cancer metastasis by targeting ARHGAP35 for protein degradation.
Downregulation of WW domain-containing oxidoreductase leads to tamoxifen-resistance by the inactivation of Hippo signaling.
NLRC3 inhibits MCT-induced pulmonary hypertension in rats via attenuating PI3K activation.
Regional Ischemic Preconditioning Has Clinical Value in Cirrhotic HCC Through MAPK Pathways.
Bavachinin exhibits antitumor activity against non‑small cell lung cancer by targeting PPARγ.
Upregulation of EPS8L3 is associated with tumorigenesis and poor prognosis in patients with liver cancer.
Cancer associated fibroblasts are distinguishable from peri-tumor fibroblasts by biological characteristics in TSCC.
Probiotic effect on Helicobacter pylori attachment and inhibition of inflammation in human gastric epithelial cells.
Inhibition of polycomb repressor complex 2 ameliorates neointimal hyperplasia by suppressing trimethylation of H3K27 in vascular smooth muscle cells.
Functional daidzein enhances the anticancer effect of topotecan and reverses BCRP-mediated drug resistance in breast cancer.
TRAF4 Promotes Fibroblast Proliferation in Keloids by Destabilizing p53 via Interacting with the Deubiquitinase USP10.
SARI attenuates colon inflammation by promoting STAT1 degradation in intestinal epithelial cells.
In vitro effect of Pannexin 1 channel on the invasion and migration of I-10 testicular cancer cells via ERK1/2 signaling pathway.
Treatment with andrographolide sulfonate provides additional benefits to imipenem in a mouse model of Klebsiella pneumoniae pneumonia.
circMTO1 promotes tumorigenesis and chemoresistance of cervical cancer via regulating miR-6893.
Kinesin family member C1 accelerates bladder cancer cell proliferation and induces epithelial-mesenchymal transition via Akt/GSK3β signaling.
Inhibiting effect of microRNA-187-3p on osteogenic differentiation of osteoblast precursor cells by suppressing cannabinoid receptor type 2.
Angiopoietin-Like Protein 4 (ANGPTL4) Induces Retinal Pigment Epithelial Barrier Breakdown by Activating Signal Transducer and Activator of Transcription 3 (STAT3): Evidence from ARPE-19 Cells Under Hypoxic Condition and Diabetic Rats.
De novo synthesis of serine and glycine fuels purine nucleotide biosynthesis in human lung cancer tissues.
lncRNA NR_038323 Suppresses Renal Fibrosis in Diabetic Nephropathy by Targeting the miR-324-3p/DUSP1 Axis.
Myosin II isoforms play distinct roles in adherens junction biogenesis.
CD36 inhibits β-catenin/c-myc-mediated glycolysis through ubiquitination of GPC4 to repress colorectal tumorigenesis.
MiR-532-3p suppresses colorectal cancer progression by disrupting the ETS1/TGM2 axis-mediated Wnt/β-catenin signaling.
Ubiquitin ligase TRIM71 suppresses ovarian tumorigenesis by degrading mutant p53.
Inhibition of MCF-7 breast cancer cell proliferation by a synthetic peptide derived from the C-terminal sequence of Orai channel.
Ribavirin Induces Polyamine Depletion via Nucleotide Depletion to Limit Virus Replication.
microRNA arm-imbalance in part from complementary targets mediated decay promotes gastric cancer progression.
NRF2-dependent gene expression promotes ciliogenesis and Hedgehog signaling.
Targeting the IL-1β/IL-1Ra pathways for the aggregation of human islet amyloid polypeptide in an ex vivo organ culture system of the intervertebral disc.
Modulation of M2 macrophage polarization by the crosstalk between Stat6 and Trim24.
OPA1 overexpression ameliorates mitochondrial cristae remodeling, mitochondrial dysfunction, and neuronal apoptosis in prion diseases.
Retromer and TBC1D5 maintain late endosomal RAB7 domains to enable amino acid-induced mTORC1 signaling.
Recurrent GNAQ mutation encoding T96S in natural killer/T cell lymphoma.
Up-regulated cathepsin C induces macrophage M1 polarization through FAK-triggered p38 MAPK/NF-κB pathway.
Altered bile acid composition and disposition in a mouse model of non-alcoholic steatohepatitis.
Extensive disruption of protein interactions by genetic variants across the allele frequency spectrum in human populations.
Near-Infrared Light-Sensitive Nano Neuro-Immune Blocker Capsule Relieves Pain and Enhances the Innate Immune Response for Necrotizing Infection.
Transforming growth factor (TGF)-β1-induced miR-133a inhibits myofibroblast differentiation and pulmonary fibrosis.
miR-146a attenuates apoptosis and modulates autophagy by targeting TAF9b/P53 pathway in doxorubicin-induced cardiotoxicity.
Exosomal transfer of miR-501 confers doxorubicin resistance and tumorigenesis via targeting of BLID in gastric cancer.
Inhibitory effect of taspine derivative TAD1822-7 on tumor cell growth and angiogenesis via suppression of EphrinB2 and related signaling pathways.
Tributyltin exposure disturbs hepatic glucose metabolism in male mice.
Chronic administration of diethylnitrosamine to induce hepatocarcinogenesis and to evaluate its synergistic effect with other hepatotoxins in mice.
Characterization of a novel separase-interacting protein and candidate new securin, Eip1p, in the fungal pathogen Candida albicans.
The estrogen-regulated lncRNA H19/miR-216a-5p axis alters stromal cell invasion and migration via ACTA2 in endometriosis.
Increased miR-214 expression suppresses cell migration and proliferation in Hirschsprung disease by interacting with PLAGL2.
Cinobufagin inhibits tumor growth by inducing apoptosis through Notch signaling pathways in human cholangiocarcinoma.
Knockdown of METTL14 inhibits the growth and invasion of cervical cancer.
Effect of NOP2 knockdown on colon cancer cell proliferation, migration, and invasion.
Baicalein and baicalin promote antitumor immunity by suppressing PD-L1 expression in hepatocellular carcinoma cells.
Potential role of M2 macrophage polarization in ventilator-induced lung fibrosis.
MiR-92a regulates endothelial progenitor cells (EPCs) by targeting GDF11 via activate SMAD2/3/FAK/Akt/eNOS pathway.
Direct Amplification of Tissue Factor:Factor VIIa Procoagulant Activity by Bile Acids Drives Intrahepatic Coagulation.
LINC00346 promotes pancreatic cancer progression through the CTCF-mediated Myc transcription.
HBx regulates transcription factor PAX8 stabilization to promote the progression of hepatocellular carcinoma.
Antioxidant activity of Coridius chinensis extracts on manganese-induced testicular damage in rats.
Genistein inhibits nasopharyngeal cancer stem cells through sonic hedgehog signaling.
MiR-100 suppresses inflammatory activation of microglia and neuronal apoptosis following spinal cord injury via TLR4/NF-κB pathway.
miR-29a promotes pathological cardiac hypertrophy by targeting the PTEN/AKT/mTOR signalling pathway and suppressing autophagy.
Silencing lncRNA SNHG6 suppresses proliferation and invasion of breast cancer cells through miR-26a/VASP axis.
NKAP functions as an oncogene in Ewing sarcoma cells partly through the AKT signaling pathway.
GSK343 induces autophagy and downregulates the AKT/mTOR signaling pathway in pancreatic cancer cells.
Ginsenoside Rg5 induces G2/M phase arrest, apoptosis and autophagy via regulating ROS-mediated MAPK pathways against human gastric cancer.
Hyperoside protects against heart failure-induced liver fibrosis in rats.
LXRα-mediated downregulation of EGFR suppress colorectal cancer cell proliferation.
LMX1B involved in the radioresistance, proliferation and migration of esophageal cancer cells.
Magnesium lithospermate B attenuates renal injury in 5/6 renal ablation/infarction rats by mitochondrial pathway of apoptosis.
ACT001, a novel PAI-1 inhibitor, exerts synergistic effects in combination with cisplatin by inhibiting PI3K/AKT pathway in glioma.
Strong anion exchange-mediated phosphoproteomics reveals extensive human non-canonical phosphorylation.
Cichorium intybus L. Extract Suppresses Experimental Gout by Inhibiting the NF-κB and NLRP3 Signaling Pathways.
Improvement of Mitochondrial Activity and Fibrosis by Resveratrol Treatment in Mice with Schistosoma japonicum Infection.
Activated spinal astrocytes contribute to the later phase of carrageenan-induced prostatitis pain.
YTHDF1 links hypoxia adaptation and non-small cell lung cancer progression.
Discovery of Novel Aryl Carboxamide Derivatives as Hypoxia-Inducible Factor 1α Signaling Inhibitors with Potent Activities of Anticancer Metastasis.
MicroRNA-29a Suppresses CD36 to Ameliorate High Fat Diet-Induced Steatohepatitis and Liver Fibrosis in Mice.
The protective effect of Phellinus linteus decoction on podocyte injury in the kidney of FSGS rats.
Systematically characterize the clinical and biological significances of 1p19q genes in 1p/19q non-codeletion glioma.
N(6)-methyladenosine modification of circNSUN2 facilitates cytoplasmic export and stabilizes HMGA2 to promote colorectal liver metastasis.
Exosomal and extracellular HMGB1 have opposite effects on SASH1 expression in rat astrocytes and glioma C6 cells.
Bromodomain-containing protein 4 contributes to renal fibrosis through the induction of epithelial-mesenchymal transition.
Human Umbilical Cord-Derived Mesenchymal Stem Cells Relieve Hind Limb Ischemia by Promoting Angiogenesis in Mice.
Dystroglycan is involved in the activation of ERK pathway inducing the change of AQP4 expression in scratch-injured astrocytes.
Endothelial cell pyroptosis plays an important role in Kawasaki disease via HMGB1/RAGE/cathespin B signaling pathway and NLRP3 inflammasome activation.
A circular RNA from APC inhibits the proliferation of diffuse large B-cell lymphoma by inactivating Wnt/β-catenin signaling via interacting with TET1 and miR-888.
Polyphenol-Rich Extracts from Toona sinensis Bark and Fruit Ameliorate Free Fatty Acid-Induced Lipogenesis through AMPK and LC3 Pathways.
TMEM18 inhibits osteogenic differentiation of rat bone marrow-derived mesenchymal stem cells by inactivating β-catenin.
Genetic loss of Gas6/Mer pathway attenuates silica-induced lung inflammation and fibrosis in mice.
Serum miR-221-3p as a new potential biomarker for depressed mood in perioperative patients.
Prolonged neutrophil retention in the wound impairs zebrafish heart regeneration after cryoinjury.
lncRNA ABHD11-AS1, regulated by the EGFR pathway, contributes to the ovarian cancer tumorigenesis by epigenetically suppressing TIMP2.
Combined MEK inhibition and tumor-associated macrophages depletion suppresses tumor growth in a triple-negative breast cancer mouse model.
Role of miR-214 in regulation of β-catenin and the malignant phenotype of melanoma.
Allele-selective lowering of mutant HTT protein by HTT-LC3 linker compounds.
Structural characterization and biological function of bivalent binding of CD2AP to intrinsically disordered domain of chikungunya virus nsP3 protein.
Upregulated PDK4 expression is a sensitive marker of increased fatty acid oxidation.
Dehydrogenase/reductase SDR family member 2 silencing sensitizes an oxaliplatin‑resistant cell line to oxaliplatin by inhibiting excision repair cross‑complementing group 1 protein expression.
KDELR2 Promotes Glioblastoma Tumorigenesis Targeted by HIF1a via mTOR Signaling Pathway.
The digestive system of the adult Hermetia illucens (Diptera: Stratiomyidae): morphological features and functional properties.
The protective effect of lithocholic acid on the intestinal epithelial barrier is mediated by the vitamin D receptor via a SIRT1/Nrf2 and NF-κB dependent mechanism in Caco-2 cells.
Transcription factor 7-like 2-associated signaling mechanism in regulating cementum generation by the NF-κB pathway.
EphA8 acts as an oncogene and contributes to poor prognosis in gastric cancer via regulation of ADAM10.
The miR-27a-3p/USP25 axis participates in the pathogenesis of recurrent miscarriage by inhibiting trophoblast migration and invasion.
GSK-3β inhibition protects the rat heart from the lipopolysaccharide-induced inflammation injury via suppressing FOXO3A activity.
Long non-coding RNA cardiac hypertrophy-associated regulator governs cardiac hypertrophy via regulating miR-20b and the downstream PTEN/AKT pathway.
TMPO-AS1 promotes cervical cancer progression by upregulating RAB14 via sponging miR-577.
Knockdown of long noncoding RNA DLEU1 suppresses the progression of renal cell carcinoma by downregulating the Akt pathway.
Deficiency of PTEN leads to aberrant chromosome segregation through downregulation of MAD2.
Downregulation of transgelin 2 promotes breast cancer metastasis by activating the reactive oxygen species/nuclear factor‑κB signaling pathway.
Identification of two novel RHO mutations in Chinese retinitis pigmentosa patients.
SNX3 suppresses the migration and invasion of colorectal cancer cells by reversing epithelial-to-mesenchymal transition via the β-catenin pathway.
Exogenous hydrogen sulfide protects against high glucose-induced apoptosis and oxidative stress by inhibiting the STAT3/HIF-1α pathway in H9c2 cardiomyocytes.
C2-lacking isoform of Nedd4-2 regulates excitatory synaptic strength through GluA1 ubiquitination-independent mechanisms.
Atsttrin reduces lipopolysaccharide-induced neuroinflammation by inhibiting the nuclear factor kappa B signaling pathway.
C9orf72 intermediate repeats are associated with corticobasal degeneration, increased C9orf72 expression and disruption of autophagy.
Delta-aminolevulinic acid synthase 2 expression in combination with iron as modifiers of disease severity in erythropoietic protoporphyria.
Transmural pressure drives proliferation of human arterial smooth muscle cells via mechanism associated with NADPH oxidase and Survivin.
IL-22 suppresses HSV-2 replication in human cervical epithelial cells.
miR-9-5p attenuates ischemic stroke through targeting ERMP1-mediated endoplasmic reticulum stress.
Serum proteomics analysis based on label-free revealed the protective effect of Chinese herbal formula Gu-Ben-Fang-Xiao.
G9a and histone deacetylases are crucial for Snail2-mediated E-cadherin repression and metastasis in hepatocellular carcinoma.
The metabolic regulator small heterodimer partner contributes to the glucose and lipid homeostasis abnormalities induced by hepatitis C virus infection.
Double-stranded RNA deaminase ADAR1 promotes the Zika virus replication by inhibiting the activation of protein kinase PKR.
Microtubule destabilization caused by silicate via HDAC6 activation contributes to autophagic dysfunction in bone mesenchymal stem cells.
Astaxanthin protects against osteoarthritis via Nrf2: a guardian of cartilage homeostasis.
Long noncoding RNA LINC01111 suppresses pancreatic cancer aggressiveness by regulating DUSP1 expression via microRNA-3924.
ZFP161 regulates replication fork stability and maintenance of genomic stability by recruiting the ATR/ATRIP complex.
CD105 Is Expressed in Ovarian Cancer Precursor Lesions and Is Required for Metastasis to the Ovary.
Tissue plasminogen activator disrupts the blood-brain barrier through increasing the inflammatory response mediated by pericytes after cerebral ischemia.
Efficient Delivery of Therapeutic siRNA by Fe(3)O(4) Magnetic Nanoparticles into Oral Cancer Cells.
Chemerin-induced macrophages pyroptosis in fetal brain tissue leads to cognitive disorder in offspring of diabetic dams.
Viral Nonstructural Protein 1 Induces Mitochondrion-Mediated Apoptosis in Mink Enteritis Virus Infection.
Nitidine chloride induces S phase cell cycle arrest and mitochondria-dependent apoptosis in HaCaT cells and ameliorates skin lesions in psoriasis-like mouse models.
Aberrant activation of RPB1 is critical for cell overgrowth in acute myeloid leukemia.
A thiazole-derived oridonin analogue exhibits antitumor activity by directly and allosterically inhibiting STAT3.
FUS-mediated dysregulation of Sema5a, an autism-related gene, in FUS mice with hippocampus-dependent cognitive deficits.
β-Caryophyllene protects against ischemic stroke by promoting polarization of microglia toward M2 phenotype via the TLR4 pathway.
Covalent Ligand Screening Uncovers a RNF4 E3 Ligase Recruiter for Targeted Protein Degradation Applications.
A dual functional ruthenium arene complex induces differentiation and apoptosis of acute promyelocytic leukemia cells.
SPOP inhibits mice pancreatic stellate cell activation by promoting FADD degradation in cerulein-induced chronic pancreatitis.
Prematurity blunts the feeding-induced stimulation of translation initiation signaling and protein synthesis in muscle of neonatal piglets.
Aurone derivatives as Vps34 inhibitors that modulate autophagy.
Regulation of insulin resistance by targeting the insulin-like growth factor 1 receptor with microRNA-122-5p in hepatic cells.
RPS7 promotes cell migration through targeting epithelial-mesenchymal transition in prostate cancer.
Identification of genes with universally upregulated or downregulated expressions in colorectal cancer.
Taurine alleviates repression of betaine-homocysteine S-methyltransferase and significantly improves the efficacy of long-term betaine treatment in a mouse model of cystathionine β-synthase-deficient homocystinuria.
Adipose-Specific Lipin-1 Overexpression Renders Hepatic Ferroptosis and Exacerbates Alcoholic Steatohepatitis in Mice.
Serine/arginine protein-specific kinase 2 promotes the development and progression of pancreatic cancer by downregulating Numb and p53.
MicroRNA-92a promotes vascular smooth muscle cell proliferation and migration through the ROCK/MLCK signalling pathway.
Ectopic expression of miR-944 impairs colorectal cancer cell proliferation and invasion by targeting GATA binding protein 6.
The pattern-recognition molecule mindin binds integrin Mac-1 to promote macrophage phagocytosis via Syk activation and NF-κB p65 translocation.
The RNA N(6)-methyladenosine modification landscape of human fetal tissues.
ERα and Wnt/β‑catenin signaling pathways are involved in angelicin‑dependent promotion of osteogenesis.
β-Catenin and Yes-Associated Protein 1 Cooperate in Hepatoblastoma Pathogenesis.
A novel function of anaphase promoting complex subunit 10 in tumor progression in non-small cell lung cancer.
Demethylation of the HACE1 gene promoter inhibits the proliferation of human liver cancer cells.
Upregulated forkhead-box A3 elevates the expression of forkhead-box A1 and forkhead-box A2 to promote metastasis in esophageal cancer.
Nano hydroxyapatite induces glioma cell apoptosis by suppressing NF-κB signaling pathway.
Attenuation of interferon regulatory factor 7 activity in local infectious sites of trachea and lung for preventing the development of acute lung injury caused by influenza A virus.
SMCR8 negatively regulates AKT and MTORC1 signaling to modulate lysosome biogenesis and tissue homeostasis.
The ALS-FTD-linked gene product, C9orf72, regulates neuronal morphogenesis via autophagy.
FAM175B promotes apoptosis by inhibiting ATF4 ubiquitination in esophageal squamous cell carcinoma.
Expression of DEC2 enhances chemosensitivity by inhibiting STAT5A in gastric cancer.
Nrf2 controls iron homeostasis in haemochromatosis and thalassaemia via Bmp6 and hepcidin.
Sox17 is required for endothelial regeneration following inflammation-induced vascular injury.
Inhibiting Glutamine-Dependent mTORC1 Activation Ameliorates Liver Cancers Driven by β-Catenin Mutations.
Thyrotropin aggravates atherosclerosis by promoting macrophage inflammation in plaques.
Adipose HuR protects against diet-induced obesity and insulin resistance.
USP36 protects proximal tubule cells from ischemic injury by stabilizing c-Myc and SOD2.
p53 suppression is essential for oncogenic SPAG5 upregulation in lung adenocarcinoma.
HMGB1 contributes to SASH1 methylation to attenuate astrocyte adhesion.
Inhibition of the IGF-1-PI3K-Akt-mTORC2 pathway in lipid rafts increases neuronal vulnerability in a genetic lysosomal glycosphingolipidosis.
PLA Electrospun Scaffolds for Three-Dimensional Triple-Negative Breast Cancer Cell Culture.
Shen Shuai IIRecipe attenuates renal injury and fibrosis in chronic kidney disease by regulating NLRP3 inflammasome and Sirt1/Smad3 deacetylation pathway.
Isodunnianol alleviates doxorubicin-induced myocardial injury by activating protective autophagy.
Estrogen negatively regulates the renal epithelial sodium channel (ENaC) by promoting Derlin-1 expression and AMPK activation.
Tumor Cell "Slimming" Regulates Tumor Progression through PLCL1/UCP1-Mediated Lipid Browning.
M2 macrophages promote NSCLC metastasis by upregulating CRYAB.
Triptolide prevents proliferation and migration of Esophageal Squamous Cell Cancer via MAPK/ERK signaling pathway.
Oral Administration of a Select Mixture of Lactobacillus and Bacillus Alleviates Inflammation and Maintains Mucosal Barrier Integrity in the Ileum of Pigs Challenged with Salmonella Infantis.
Hic-5 regulates Src-induced invadopodia rosette formation and organization.
FGFR2 Promotes Expression of PD-L1 in Colorectal Cancer via the JAK/STAT3 Signaling Pathway.
Sodium ferulate protects against influenza virus infection by activation of the TLR7/9-MyD88-IRF7 signaling pathway and inhibition of the NF-κB signaling pathway.
The Glycoprotein and Nucleocapsid Protein of Hantaviruses Manipulate Autophagy Flux to Restrain Host Innate Immune Responses.
ELF4 facilitates innate host defenses against Plasmodium by activating transcription of Pf4 and Ppbp.
Cynomorium songaricum Rupr demonstrates phytoestrogenic or phytoandrogenic like activities that attenuates benign prostatic hyperplasia via regulating steroid 5-α-reductase.
Anterior Gradient-2 monoclonal antibody inhibits lung cancer growth and metastasis by upregulating p53 pathway and without exerting any toxicological effects: A preclinical study.
USP39 regulates DNA damage response and chemo-radiation resistance by deubiquitinating and stabilizing CHK2.
Astragaloside IV Regulates the PI3K/Akt/HO-1 Signaling Pathway and Inhibits H9c2 Cardiomyocyte Injury Induced by Hypoxia-Reoxygenation.
Inactivation of Cyclic AMP Response Element Transcription Caused by Constitutive p38 Activation Is Mediated by Hyperphosphorylation-Dependent CRTC2 Nucleocytoplasmic Transport.
Fatty acid-binding protein 3 contributes to ischemic heart injury by regulating cardiac myocyte apoptosis and MAPK pathways.
Inhibition of mitochondrial complex I activity attenuates neointimal hyperplasia by inhibiting smooth muscle cell proliferation and migration.
Reactivation of nonsense-mediated mRNA decay protects against C9orf72 dipeptide-repeat neurotoxicity.
Sirt3 mediates the protective effect of hydrogen in inhibiting ROS-induced retinal senescence.
Oxytocin facilitates the proliferation, migration and osteogenic differentiation of human periodontal stem cells in vitro.
Nr5a2 promotes cancer stem cell properties and tumorigenesis in nonsmall cell lung cancer by regulating Nanog.
MicroRNA-186 is associated with hypoxia-inducible factor-1α expression in chronic obstructive pulmonary disease.
Gallic Acid Suppresses Cardiac Hypertrophic Remodeling and Heart Failure.
Herbal decoctosome is a novel form of medicine.
Pb disrupts autophagic flux through inhibiting the formation and activity of lysosomes in neural cells.
Role of heparan sulfate in the Zika virus entry, replication, and cell death.
NS38 is required for aquareovirus replication via interaction with viral core proteins and host eIF3A.
Continuous translation of circularized mRNA improves recombinant protein titer.
Regulation of Neurotransmitter Release by Amyloid Precursor Protein Through Synapsin Phosphorylation.
Bromodomain‑containing protein 7 sensitizes breast cancer cells to paclitaxel by activating Bcl2‑antagonist/killer protein.
miR-4739 mediates pleural fibrosis by targeting bone morphogenetic protein 7.
The HNF1α-Regulated LncRNA HNF1α-AS1 Is Involved in the Regulation of Cytochrome P450 Expression in Human Liver Tissues and Huh7 Cells.
3D human bone marrow stromal and endothelial cell spheres promote bone healing in an osteogenic niche.
Oncostatin M-induced upregulation of SDF-1 improves Bone marrow stromal cell migration in a rat middle cerebral artery occlusion stroke model.
PARylation regulates stress granule dynamics, phase separation, and neurotoxicity of disease-related RNA-binding proteins.
β‑elemene inhibits oxygen‑induced retinal neovascularization via promoting miR‑27a and reducing VEGF expression.
Modulation of α-adrenoceptor signalling protects photoreceptors after retinal detachment by inhibiting oxidative stress and inflammation.
NF-κB and Poly (ADP-ribose) Polymerase 1 Form a Positive Feedback Loop that Regulates DNA Repair in Acute Myeloid Leukemia Cells.
miRNA profiling in the hippocampus of attention-deficit/hyperactivity disorder rats.
MET mutation causes muscular dysplasia and arthrogryposis.
MLKL deficiency inhibits DSS-induced colitis independent of intestinal microbiota.
Combinatory FK506 and Minocycline Treatment Alleviates Prion-Induced Neurodegenerative Events via Caspase-Mediated MAPK-NRF2 Pathway.
Circadian control of stress granules by oscillating EIF2α.
Neuroprotective Effect of Dioscin on the Aging Brain.
Silencing of XRCC4 increases radiosensitivity of triple-negative breast cancer cells.
Cysteine Dioxygenase Regulates the Epithelial Morphogenesis of Mammary Gland via Cysteine Sulfinic Acid.
Viral-Mediated AURKB Cleavage Promotes Cell Segregation and Tumorigenesis.
MicroRNA-29a Disrupts DNMT3b to Ameliorate Diet-Induced Non-Alcoholic Steatohepatitis in Mice.
H(2)S restores the cardioprotective effects of ischemic post-conditioning by upregulating HB-EGF/EGFR signaling.
Ribosomal Proteins Regulate MHC Class I Peptide Generation for Immunosurveillance.
Genetically Encoded FapR-NLuc as a Biosensor to Determine Malonyl-CoA in Situ at Subcellular Scales.
Discovery of human TyrRS inhibitors by structure-based virtual screening, structural optimization, and bioassays.
Detecting Secretory Proteins by Acoustic Droplet Ejection in Multiplexed High-Throughput Applications.
A GPR17-cAMP-Lactate Signaling Axis in Oligodendrocytes Regulates Whole-Body Metabolism.
p53-targeted lincRNA-p21 acts as a tumor suppressor by inhibiting JAK2/STAT3 signaling pathways in head and neck squamous cell carcinoma.
Porcine Hemagglutinating Encephalomyelitis Virus Activation of the Integrin α5β1-FAK-Cofilin Pathway Causes Cytoskeletal Rearrangement To Promote Its Invasion of N2a Cells.
PRL-3 Promotes Ubiquitination and Degradation of AURKA and Colorectal Cancer Progression via Dephosphorylation of FZR1.
HOXD-AS1 promotes the epithelial to mesenchymal transition of ovarian cancer cells by regulating miR-186-5p and PIK3R3.
Candidate-based screening via gene modulation in human neurons and astrocytes implicates FERMT2 in Aβ and TAU proteostasis.
In Vitro and In Vivo Anti-Inflammatory Effects of Polyphyllin VII through Downregulating MAPK and NF-κB Pathways.
Gα(i2) Signaling Regulates Inflammasome Priming and Cytokine Production by Biasing Macrophage Phenotype Determination.
Molecular characterization of caspase-8-like and its expression induced by microcystin-LR in grass carp (Ctenopharygodon idella).
Defective Central Immune Tolerance Induced by High-Dose D-Galactose Resembles Aging.
Exosomal cyclophilin A as a novel noninvasive biomarker for Epstein-Barr virus associated nasopharyngeal carcinoma.
Activation of cGMP/PKG/p65 signaling associated with PDE5-Is downregulates CCL5 secretion by CD8 (+) T cells in benign prostatic hyperplasia.
Minimally modified low-density lipoprotein upregulates the ET(B) and α(1) receptors in mouse mesenteric arteries in vivo by activating the PI3K/Akt pathway.
Deficiency of ZnT8 Promotes Adiposity and Metabolic Dysfunction by Increasing Peripheral Serotonin Production.
Activated CRH receptors inhibit autophagy by repressing conversion of LC3BI to LC3BII.
A comprehensive study on donor-matched comparisons of three types of mesenchymal stem cells-containing cells from human dental tissue.
Effects of 3-dimensional Bioprinting Alginate/Gelatin Hydrogel Scaffold Extract on Proliferation and Differentiation of Human Dental Pulp Stem Cells.
The circRNA circPTPRA suppresses epithelial-mesenchymal transitioning and metastasis of NSCLC cells by sponging miR-96-5p.
FasL on decidual macrophages mediates trophoblast apoptosis: A potential cause of recurrent miscarriage.
Obesity-associated family with sequence similarity 13, member A (FAM13A) is dispensable for adipose development and insulin sensitivity.
Probenecid Relieves Cerebral Dysfunction of Sepsis by Inhibiting Pannexin 1-Dependent ATP Release.
Early Pattern of Epstein-Barr Virus Infection in Gastric Epithelial Cells by "Cell-in-cell".
Reduced asymmetric dimethylarginine accumulation through inhibition of the type I protein arginine methyltransferases promotes renal fibrosis in obstructed kidneys.
Suppression of puerarin on polymethylmethacrylate-induced lesion of peri-implant by inhibiting NF-κB activation in vitro and in vivo.
An SOD1 deficiency aggravates proteasome inhibitor bortezomib-induced testicular damage in mice.
The p53/miRNAs/Ccna2 pathway serves as a novel regulator of cellular senescence: Complement of the canonical p53/p21 pathway.
Enhanced responsiveness of platelets to vicagrel in IL-10-deficient mice through STAT3-dependent up-regulation of the hydrolase arylacetamide deacetylase in the intestine.
Inhibition of Wee1 sensitizes AML cells to ATR inhibitor VE-822-induced DNA damage and apoptosis.
AC002454.1 and CDK6 synergistically promote endometrial cell migration and invasion in endometriosis.
Hydrogen sulfide protects against DSS-induced colitis by inhibiting NLRP3 inflammasome.
Amplification of USP13 drives non-small cell lung cancer progression mediated by AKT/MAPK signaling.
Antithrombotic Effect of shRNA Target F12 Mediated by Adeno-Associated Virus.
Insulin-like growth factor-1 attenuates oxidative stress-induced hepatocyte premature senescence in liver fibrogenesis via regulating nuclear p53-progerin interaction.
Death-associated protein kinase 3 deficiency alleviates vascular calcification via AMPK-mediated inhibition of endoplasmic reticulum stress.
Alternative transcription start site selection in ACSS2 controls its nuclear localization and promotes ribosome biosynthesis in hepatocellular carcinoma.
NLRC5 inhibits neointima formation following vascular injury and directly interacts with PPARγ.
Pervasive Chromatin-RNA Binding Protein Interactions Enable RNA-Based Regulation of Transcription.
Transcriptional Regulation of gga-miR-451 by AhR:Arnt in Mycoplasma gallisepticum (HS Strain) Infection.
miR-211 facilitates platinum chemosensitivity by blocking the DNA damage response (DDR) in ovarian cancer.
Identification of metabolic vulnerabilities of receptor tyrosine kinases-driven cancer.
Quercetin inhibits kidney fibrosis and the epithelial to mesenchymal transition of the renal tubular system involving suppression of the Sonic Hedgehog signaling pathway.
Low Polymerase Activity Attributed to PA Drives the Acquisition of the PB2 E627K Mutation of H7N9 Avian Influenza Virus in Mammals.
Induction of Fibrosis and Autophagy in Kidney Cells by Vinyl Chloride.
Cellular Interleukin Enhancer-Binding Factor 2, ILF2, Inhibits Japanese Encephalitis Virus Replication In Vitro.
Insulin transcriptionally down-regulates carboxylesterases through pregnane X receptor in an Akt-dependent manner.
NOL12 Repression Induces Nucleolar Stress-Driven Cellular Senescence and Is Associated with Normative Aging.
Dihydromyricetin alleviates acetaminophen-induced liver injury via the regulation of transformation, lipid homeostasis, cell death and regeneration.
Fine particulate matter-induced cardiovascular injury is associated with NLRP3 inflammasome activation in Apo E(-/-) mice.
Heartland virus antagonizes type I and III interferon antiviral signaling by inhibiting phosphorylation and nuclear translocation of STAT2 and STAT1.
Small molecule inhibitor of TGF-β signaling enables robust osteogenesis of autologous GMSCs to successfully repair minipig severe maxillofacial bone defects.
CDK9 modulates circadian clock by attenuating REV-ERBα activity.
Arsenic trioxide inhibits EMT in hepatocellular carcinoma by promoting lncRNA MEG3 via PKM2.
Targeting ATGL to rescue BSCL2 lipodystrophy and its associated cardiomyopathy.
microRNA-378a Regulates the Reactive Oxygen Species (ROS)/Phosphatidylinositol 3-Kinases (PI3K)/AKT Signaling Pathway in Human Lens Epithelial Cells and Cataract.
Role of TMPRSS4 Modulation in Breast Cancer Cell Proliferation.
Nrf2 deficiency aggravates Angiotensin II-induced cardiac injury by increasing hypertrophy and enhancing IL-6/STAT3-dependent inflammation.
Aerobic exercise regulates synaptic transmission and reactive oxygen species production in the paraventricular nucleus of spontaneously hypertensive rats.
Esrrb plays important roles in maintaining self-renewal of trophoblast stem cells (TSCs) and reprogramming somatic cells to induced TSCs.
Cardamonin from a medicinal herb protects against LPS-induced septic shock by suppressing NLRP3 inflammasome.
IL-25 promotes cisplatin resistance of lung cancer cells by activating NF-κB signaling pathway to increase of major vault protein.
Anti-inflammatory and antitumour activity of various extracts and compounds from the fruits of Piper longum L.
Knockdown of circulating C1 inhibitor induces neurovascular impairment, glial cell activation, neuroinflammation, and behavioral deficits.
MicroRNA-135b alleviates MPP(+)-mediated Parkinson's disease in in vitro model through suppressing FoxO1-induced NLRP3 inflammasome and pyroptosis.
APS could potentially activate hepatic insulin signaling in HFD-induced IR mice.
MicroRNA-221 sensitizes chronic myeloid leukemia cells to imatinib by targeting STAT5.
Comparison of intracellular responses between HBV genotype A and C infection in human hepatocyte chimeric mice.
Clearance of apoptotic cells by mesenchymal stem cells contributes to immunosuppression via PGE2.
The potential role of pregnancy-associated plasma protein-A2 in angiogenesis and development of preeclampsia.
Luteolin suppresses colorectal cancer cell metastasis via regulation of the miR‑384/pleiotrophin axis.
Dynasore Suppresses mTORC1 Activity and Induces Autophagy to Regulate the Clearance of Protein Aggregates in Neurodegenerative Diseases.
Reduction of PGRN increased fibrosis during skin wound healing in mice.
Activation of prostaglandin EP4 receptor attenuates the induction of cyclooxygenase-2 expression by EP2 receptor activation in human amnion fibroblasts: implications for parturition.
Resveratrol targets TyrRS acetylation to protect against radiation-induced damage.
Notch signaling activation induces cell death in MAPKi-resistant melanoma cells.
Molecular basis of vasohibins-mediated detyrosination and its impact on spindle function and mitosis.
Alcohol dehydrogenase of Candida albicans triggers differentiation of THP-1 cells into macrophages.
Neuroprotection of Fasting Mimicking Diet on MPTP-Induced Parkinson's Disease Mice via Gut Microbiota and Metabolites.
Harnessing the anti-cancer natural product nimbolide for targeted protein degradation.
RTN1-C is involved in high glucose-aggravated neuronal cell subjected to oxygen-glucose deprivation and reoxygenation injury via endoplasmic reticulum stress.
Long-term pulmonary exposure to multi-walled carbon nanotubes promotes breast cancer metastatic cascades.
Aqueous extract of Salvia miltiorrhiza Bunge-Radix Puerariae herb pair ameliorates diabetic vascular injury by inhibiting oxidative stress in streptozotocin-induced diabetic rats.
Effect of Hypoxia on the Muscle Fiber Switching Signal Pathways CnA/NFATc1 and Myostatin in Mouse Myocytes.
Hsa_circ_0023404 enhances cervical cancer metastasis and chemoresistance through VEGFA and autophagy signaling by sponging miR-5047.
Taurine protects against arsenic trioxide-induced insulin resistance via ROS-Autophagy pathway in skeletal muscle.
Long noncoding RNA actin filament-associated protein 1 antisense RNA 1 promotes malignant phenotype through binding with lysine-specific demethylase 1 and repressing HMG box-containing protein 1 in non-small-cell lung cancer.
Lysine glutarylation in human sperm is associated with progressive motility.
microRNA-16-5p promotes 3T3-L1 adipocyte differentiation through regulating EPT1.
Comparative interactome analysis reveals distinct and overlapping properties of Raf family kinases.
Long noncoding RNA PCAT1, a novel serum-based biomarker, enhances cell growth by sponging miR-326 in oesophageal squamous cell carcinoma.
TSPAN12 Precedes Tumor Proliferation by Cell Cycle Control in Ovarian Cancer.
LncRNA-H19 promotes hepatic lipogenesis by directly regulating miR-130a/PPARγ axis in non-alcoholic fatty liver disease.
A novel RP2 missense mutation Q158P identified in an X-linked retinitis pigmentosa family impaired RP2 protein stability.
Melatonin attenuates cadmium-induced ovulatory dysfunction by suppressing endoplasmic reticulum stress and cell apoptosis.
MiR-205 mediated APC regulation contributes to pancreatic cancer cell proliferation.
Osteoprotegerin (OPG) Promotes Recruitment of Endothelial Progenitor Cells (EPCs) via CXCR4 Signaling Pathway to Improve Bone Defect Repair.
Simultaneous knockdown of YAP and TAZ increases apoptosis of hepatocellular carcinoma cells under hypoxic condition.
Diallyl Disulfide Induces Apoptosis and Autophagy in Human Osteosarcoma MG-63 Cells through the PI3K/Akt/mTOR Pathway.
Blood autophagy defect causes accelerated non-hematopoietic organ aging.
Inhibitory Effects of Oxymatrine on Transdifferentiation of Neonatal Rat Cardiac Fibroblasts to Myofibroblasts Induced by Aldosterone via Keap1/Nrf2 Signaling Pathways In Vitro.
SFRS11 Loss Leads to Aging-Associated Cognitive Decline by Modulating LRP8 and ApoE.
Structural and functional analyses of hepatitis B virus X protein BH3-like domain and Bcl-xL interaction.
CD4 Expression and Env Conformation Are Critical for HIV-1 Restriction by SERINC5.
A novel, highly-water-soluble apigenin derivative provides neuroprotection following ischemia in male rats by regulating the ERK/Nrf2/HO-1 pathway.
LncRNA FOXD2-AS1 plays an oncogenic role in hepatocellular carcinoma through epigenetically silencing CDKN1B(p27) via EZH2.
Matrine inhibits IL-1β secretion in primary porcine alveolar macrophages through the MyD88/NF-κB pathway and NLRP3 inflammasome.
KHDRBS3 regulates the permeability of blood-tumor barrier via cDENND4C/miR-577 axis.
Insulin-like growth factor 2 mRNA binding protein 2 promotes aerobic glycolysis and cell proliferation in pancreatic ductal adenocarcinoma via stabilizing GLUT1 mRNA.
Knockdown ATG4C inhibits gliomas progression and promotes temozolomide chemosensitivity by suppressing autophagic flux.
Activation of 20-HETE/PPARs involved in reno-therapeutic effect of naringenin on diabetic nephropathy.
Toxicological exploration of peptide-based cationic liposomes in siRNA delivery.
Exosomal miR-1229 derived from colorectal cancer cells promotes angiogenesis by targeting HIPK2.
Phenylephrine Alleviates (131)I Radiation Damage in Submandibular Gland Through Maintaining Mitochondrial Homeostasis.
Extracellular matrix remodeling effects of serum amyloid A1 in the human amnion: Implications for fetal membrane rupture.
Overexpression of P2X4 receptor in Schwann cells promotes motor and sensory functional recovery and remyelination via BDNF secretion after nerve injury.
Neuroprotective effects of Astilbin on MPTP-induced Parkinson's disease mice: Glial reaction, α-synuclein expression and oxidative stress.
BMAL1 knockout macaque monkeys display reduced sleep and psychiatric disorders.
HUS1 checkpoint clamp component (HUS1) is a potential tumor suppressor in primary hepatocellular carcinoma.
ERp57‑small interfering RNA silencing can enhance the sensitivity of drug‑resistant human ovarian cancer cells to paclitaxel.
MiR-20a Plays a Key Regulatory Role in the Repair of Spinal Cord Dorsal Column Lesion via PDZ-RhoGEF/RhoA/GAP43 Axis in Rat.
Heme oxygenase-1 prevents heart against myocardial infarction by attenuating ischemic injury-induced cardiomyocytes senescence.
DPSCs seeded in acellular nerve grafts processed by Myroilysin improve nerve regeneration.
Dual regulatory role of CCNA2 in modulating CDK6 and MET-mediated cell-cycle pathway and EMT progression is blocked by miR-381-3p in bladder cancer.
Chromium(VI) promotes cell migration through targeting epithelial-mesenchymal transition in prostate cancer.
MiR-10b suppresses the growth and metastasis of colorectal cancer cell by targeting FGF13.
Characterization and proteomic profiling of pancreatic cancer-derived serum exosomes.
Combined detection of estrogen and tumor markers is an important reference factor in the diagnosis and prognosis of lung cancer.
EETs/PPARs activation together mediates the preventive effect of naringenin in high glucose-induced cardiomyocyte hypertrophy.
Ginsenoside Rd contributes the attenuation of cardiac hypertrophy in vivo and in vitro.
Role of bone morphogenetic protein-2/4 in astrocyte activation in neuropathic pain.
Zingerone Nanotetramer Strengthened the Polypharmacological Efficacy of Zingerone on Human Hepatoma Cell Lines.
A scorpion venom peptide Ev37 restricts viral late entry by alkalizing acidic organelles.
The deregulation of STIM1 and store operative calcium entry impaired aortic smooth muscle cells contractility in aortic medial degeneration.
DDX19 Inhibits Type I Interferon Production by Disrupting TBK1-IKKε-IRF3 Interactions and Promoting TBK1 and IKKε Degradation.
Atoh1 Controls Primary Cilia Formation to Allow for SHH-Triggered Granule Neuron Progenitor Proliferation.
The Plk1 kinase negatively regulates the Hedgehog signaling pathway by phosphorylating Gli1.
Acetaldehyde dehydrogenase 2 interactions with LDLR and AMPK regulate foam cell formation.
LncRNA SNHG12 inhibits miR-199a to upregulate SIRT1 to attenuate cerebral ischemia/reperfusion injury through activating AMPK signaling pathway.
Sphingosine 1 phosphate receptor-1 (S1P1) promotes tumor-associated regulatory T cell expansion: leading to poor survival in bladder cancer.
Genome-wide CRISPR Analysis Identifies Substrate-Specific Conjugation Modules in ER-Associated Degradation.
Transfer of Extracellular Vesicle-Associated-RNAs Induces Drug Resistance in ALK-Translocated Lung Adenocarcinoma.
Cathepsin C promotes microglia M1 polarization and aggravates neuroinflammation via activation of Ca(2+)-dependent PKC/p38MAPK/NF-κB pathway.
Hepatitis B e Antigen Inhibits NF-κB Activity by Interrupting K63-Linked Ubiquitination of NEMO.
Binding of cellular nucleolin with the viral core RNA G-quadruplex structure suppresses HCV replication.
N6-methyladenosine modification and METTL3 modulate enterovirus 71 replication.
Histone Demethylase KDM4B Promotes DNA Damage by Activating Long Interspersed Nuclear Element-1.
FAPP2 promotes tumor cell growth in human colon cancer through activation of Wnt signaling.
Piezo1 mediates angiogenesis through activation of MT1-MMP signaling.
Different Isoforms of the Neuronal Guidance Molecule Slit2 Directly Cause Chemoattraction or Chemorepulsion of Human Neutrophils.
MiR-26a-5p Inhibits Cell Proliferation and Enhances Doxorubicin Sensitivity in HCC Cells via Targeting AURKA.
Colon Cancer Cell Secretes EGF to Promote M2 Polarization of TAM Through EGFR/PI3K/AKT/mTOR Pathway.
MMP13 inhibition rescues cognitive decline in Alzheimer transgenic mice via BACE1 regulation.
Genotoxic stress causes the accumulation of DNA-dependent protein kinase catalytic subunit phosphorylated at serine 2056 at nuclear speckles and alters pre-mRNA alternative splicing.
High expression of SLC17A9 correlates with poor prognosis in colorectal cancer.
MicroRNA-5195-3p plays a suppressive role in cell proliferation, migration and invasion by targeting MYO6 in human non-small cell lung cancer.
Early onset developmental delay and epilepsy in pediatric patients with WDR45 variants.
Tunicamycin enhances the suppressive effects of cisplatin on lung cancer growth through PTX3 glycosylation via AKT/NF-κB signaling pathway.
Increased levels of serum pigment epithelium-derived factor aggravate proteinuria via induction of podocyte actin rearrangement.
Rapid depletion of ESCRT protein Vps4 underlies injury-induced autophagic impediment and Wallerian degeneration.
CXCR4 enhances cisplatin resistance of human tongue squamous cell carcinoma.
Chlamydia trachomatis plasmid-encoded protein Pgp3 inhibits apoptosis via the PI3K-AKT-mediated MDM2-p53 axis.
The Effects of Mitogen-activated Protein Kinase Signaling Pathways on Lipopolysaccharide-mediated Osteo/Odontogenic Differentiation of Stem Cells from the Apical Papilla.
Down-regulation of lncRNA OGFRP1 induces autophagy and growth inhibition by AKT/mTOR signaling pathway in HCAECs.
Investigating a chimeric anti-mouse PDGFRα antibody as a radiosensitizer in primary mouse sarcomas.
Antiviral activity of bone morphogenetic proteins and activins.
Decrease of GSK3β Ser-9 Phosphorylation Induced Osteoblast Apoptosis in Rat Osteoarthritis Model.
Acetylation of AGO2 promotes cancer progression by increasing oncogenic miR-19b biogenesis.
Lipopolysaccharide from Escherichia coli stimulates osteogenic differentiation of human periodontal ligament stem cells through Wnt/β-catenin-induced TAZ elevation.
Drastic induction of MMP-7 by cortisol in the human amnion: implications for membrane rupture at parturition.
Bisphenol A exposure alters placentation and causes preeclampsia-like features in pregnant mice involved in reprogramming of DNA methylation of WNT2.
PPPDE1 promotes hepatocellular carcinoma development by negatively regulate p53 and apoptosis.
Otx2 enhances transdifferentiation of Müller cells-derived retinal stem cells into photoreceptor-like cells.
Phorbol esters induce PLVAP expression via VEGF and additional secreted molecules in MEK1-dependent and p38, JNK and PI3K/Akt-independent manner.
Nucleoporin 107 facilitates the nuclear export of Scn5a mRNA to regulate cardiac bioelectricity.
Glucose Signaling Is Connected to Chromosome Segregation Through Protein Kinase A Phosphorylation of the Dam1 Kinetochore Subunit in Saccharomycescerevisiae.
Endogenous cholesterol ester hydroperoxides modulate cholesterol levels and inhibit cholesterol uptake in hepatocytes and macrophages.
Proteomic Profiling of LPS-Induced Macrophage-Derived Exosomes Indicates Their Involvement in Acute Liver Injury.
miR-140-5p inhibits cell proliferation and invasion in colorectal carcinoma by targeting SOX4.
miR-7-5p inhibits cell migration and invasion in glioblastoma through targeting SATB1.
Ebselen protects rat hearts against myocardial ischemia-reperfusion injury.
Motor Neuron Abnormalities Correlate with Impaired Movement in Zebrafish that Express Mutant Superoxide Dismutase 1.
Doxorubicin conjugated with nanodiamonds and in free form commit glioblastoma cells to heterodromous fates.
Interaction of estrogen receptor β5 and interleukin 6 receptor in the progression of non-small cell lung cancer.
Coupling function of cyclin-dependent kinase 2 and Septin2 in the promotion of hepatocellular carcinoma.
MiR-23a-3p acts as an oncogene and potential prognostic biomarker by targeting PNRC2 in RCC.
Long non-coding RNA SNHG6 enhances cell proliferation, migration and invasion by regulating miR-26a-5p/MAPK6 in breast cancer.
Noradrenergic depletion causes sex specific alterations in the endocannabinoid system in the Murine prefrontal cortex.
Combined Single-Cell Profiling of lncRNAs and Functional Screening Reveals that H19 Is Pivotal for Embryonic Hematopoietic Stem Cell Development.
SNHG1 promotes malignant biological behaviors of glioma cells via microRNA-154-5p/miR-376b-3p- FOXP2- KDM5B participating positive feedback loop.
Increased expression of thymic stromal lymphopoietin receptor in a rat model of middle cerebral artery occlusion.
Heterozygous Tbk1 loss has opposing effects in early and late stages of ALS in mice.
LPCAT1 promotes brain metastasis of lung adenocarcinoma by up-regulating PI3K/AKT/MYC pathway.
Lanthanum chloride induces autophagy in rat hippocampus through ROS-mediated JNK and AKT/mTOR signaling pathways.
High-fat and high-glucose microenvironment decreases Runx2 and TAZ expression and inhibits bone regeneration in the mouse.
Novel metabolic disorders in skeletal muscle of Lipodystrophic Bscl2/Seipin deficient mice.
Curcumae Radix Extract Decreases Mammary Tumor-Derived Lung Metastasis via Suppression of C-C Chemokine Receptor Type 7 Expression.
Involvement of serum amyloid A1 in the rupture of fetal membranes through induction of collagen I degradation.
Long non-coding RNA FAM84B-AS promotes resistance of gastric cancer to platinum drugs through inhibition of FAM84B expression.
Ankyrin-G regulated epithelial phenotype is required for mouse lens morphogenesis and growth.
Fragment-based drug discovery of triazole inhibitors to block PDEδ-RAS protein-protein interaction.
Host HDAC4 regulates the antiviral response by inhibiting the phosphorylation of IRF3.
MiR-26b suppresses hepatocellular carcinoma development by negatively regulating ZNRD1 and Wnt/β-catenin signaling.
Upregulation of CYP2E1 expression causes oxidative damage induced by 2-chloroethanol in primary cultured rat astrocytes.
Bioactive molecule Icariin inhibited proliferation while enhanced apoptosis and autophagy of rat airway smooth muscle cells in vitro.
Upregulated Expression of CUX1 Correlates with Poor Prognosis in Glioma Patients: a Bioinformatic Analysis.
Molecular mechanism of Bisphenol A on androgen receptor antagonism.
miR-124 ameliorates depressive-like behavior by targeting STAT3 to regulate microglial activation.
Ribociclib (LEE011) suppresses cell proliferation and induces apoptosis of MDA-MB-231 by inhibiting CDK4/6-cyclin D-Rb-E2F pathway.
Cancer cell membrane cloaking nanoparticles for targeted co-delivery of doxorubicin and PD-L1 siRNA.
Palmitoylome profiling indicates that androgens regulate the palmitoylation of α‑tubulin in prostate cancer‑derived LNCaP cells and supernatants.
Intrathecal injection of dexmedetomidine ameliorates chronic neuropathic pain via the modulation of MPK3/ERK1/2 in a mouse model of chronic neuropathic pain.
Mebendazole elicits potent antimyeloma activity by inhibiting the USP5/c-Maf axis.
Epigenetic regulation of TIMP1 expression by 8-oxoguanine DNA glycosylase-1 binding to DNA:RNA hybrid.
Silencing ubiquitin-conjugating enzyme 2C inhibits proliferation and epithelial-mesenchymal transition in pancreatic ductal adenocarcinoma.
Rotenone protects against β-cell apoptosis and attenuates type 1 diabetes mellitus.
STRIP2 silencing inhibits vascular smooth muscle cell proliferation and migration via P38-AKT-MMP-2 signaling pathway.
HOXC13-AS promotes breast cancer cell growth through regulating miR-497-5p/PTEN axis.
Integrated analysis of transcriptome data revealed MMP3 and MMP13 as critical genes in anaplastic thyroid cancer progression.
Critical roles of PI3K/Akt/NF‑κB survival axis in angiotensin II‑induced podocyte injury.
PTEN-knockdown disrupts the morphology, growth pattern and function of Nthy-Ori 3-1 cells by downregulating PAX8 expression.
Receptor tyrosine kinase expression in high-grade gliomas before and after chemoradiotherapy.
Caffeic acid reduces A53T α-synuclein by activating JNK/Bcl-2-mediated autophagy in vitro and improves behaviour and protects dopaminergic neurons in a mouse model of Parkinson's disease.
Identification of viral SIM-SUMO2-interaction inhibitors for treating primary effusion lymphoma.
Genetic ablation and pharmacological inhibition of immunosubunit β5i attenuates cardiac remodeling in deoxycorticosterone-acetate (DOCA)-salt hypertensive mice.
16 T high static magnetic field inhibits receptor activator of nuclear factor kappa-Β ligand-induced osteoclast differentiation by regulating iron metabolism in Raw264.7 cells.
Snail2 induced E-cadherin suppression and metastasis in lung carcinoma facilitated by G9a and HDACs.
Platelet endothelial aggregation receptor-1 regulates bovine muscle satellite cell migration and differentiation via integrin beta-1 and focal adhesion kinase.
Down-regulated long non-coding RNA PVT1 contributes to gestational diabetes mellitus and preeclampsia via regulation of human trophoblast cells.
Epigallocatechin-3-gallate inhibits tumor angiogenesis: involvement of endoglin/Smad1 signaling in human umbilical vein endothelium cells.
Ferulic acid increases intestinal Lactobacillus and improves cardiac function in TAC mice.
Endocytic degradation of ErbB2 mediates the effectiveness of neratinib in the suppression of ErbB2-positive ovarian cancer.
Forkhead box C1 promotes metastasis and invasion of non-small cell lung cancer by binding directly to the lysyl oxidase promoter.
Dietary Antioxidant Trans-Cinnamaldehyde Reduced Visfatin-Induced Breast Cancer Progression: In Vivo and In Vitro Study.
Rice Protein Exerts Anti-Inflammatory Effect in Growing and Adult Rats via Suppressing NF-κB Pathway.
Role of linc00174/miR-138-5p (miR-150-5p)/FOSL2 Feedback Loop on Regulating the Blood-Tumor Barrier Permeability.
Grape Seed Proanthocyanidins Induce Autophagy and Modulate Survivin in HepG2 Cells and Inhibit Xenograft Tumor Growth in Vivo.
NOS1 inhibits the interferon response of cancer cells by S-nitrosylation of HDAC2.
Astragaloside IV protects against diabetic nephropathy via activating eNOS in streptozotocin diabetes-induced rats.
Celastrol Inhibits Dopaminergic Neuronal Death of Parkinson's Disease through Activating Mitophagy.
Liver Soluble Epoxide Hydrolase Regulates Behavioral and Cellular Effects of Chronic Stress.
BMP10 preserves cardiac function through its dual activation of SMAD-mediated and STAT3-mediated pathways.
The regulatory effect of microRNA-21a-3p on the promotion of telocyte angiogenesis mediated by PI3K (p110α)/AKT/mTOR in LPS induced mice ARDS.
Antiviral activity of interleukin-11 as a response to porcine epidemic diarrhea virus infection.
Integrated Metabolomics and Network Pharmacology Strategy-Driven Active Traditional Chinese Medicine Ingredients Discovery for the Alleviation of Cisplatin Nephrotoxicity.
Hypothalamic paraventricular nucleus neurons activated by estrogen GPER1 receptors promote anti-inflammation effects in the early stage of colitis.
The Human Cytomegalovirus Nonstructural Glycoprotein UL148 Reorganizes the Endoplasmic Reticulum.
The Combination of Adipose-derived Schwann-like Cells and Acellular Nerve Allografts Promotes Sciatic Nerve Regeneration and Repair through the JAK2/STAT3 Signaling Pathway in Rats.
Silencing TTK expression inhibits the proliferation and progression of prostate cancer.
The exocyst complex regulates insulin-stimulated glucose uptake of skeletal muscle cells.
The focal adhesion scaffold protein Hic-5 regulates vimentin organization in fibroblasts.
Histone deacetylase 6 inhibitor ACY1215 offers a protective effect through the autophagy pathway in acute liver failure.
Paper/polymer composited microfluidic platform for screening cell viability and protein expression under a chemical gradient environment.
Uhrf1-Mediated Tnf-α Gene Methylation Controls Proinflammatory Macrophages in Experimental Colitis Resembling Inflammatory Bowel Disease.
Downregulation of TMPRSS4 Enhances Triple-Negative Breast Cancer Cell Radiosensitivity Through Cell Cycle and Cell Apoptosis Process Impairment.
Reduced m6A modification predicts malignant phenotypes and augmented Wnt/PI3K-Akt signaling in gastric cancer.
RECQL5 plays an essential role in maintaining genome stability and viability of triple-negative breast cancer cells.
Dexmedetomidine alleviates LPS-induced apoptosis and inflammation in macrophages by eliminating damaged mitochondria via PINK1 mediated mitophagy.
Sulforaphane inhibits gastric cancer stem cells via suppressing sonic hedgehog pathway.
Angiogenic Factor AGGF1-Primed Endothelial Progenitor Cells Repair Vascular Defect in Diabetic Mice.
Steroid-Enriched Fraction of Achyranthes bidentata Protects Amyloid β Peptide 1-40-Induced Cognitive Dysfunction and Neuroinflammation in Rats.
Pyrroline-5-Carboxylate Reductase 1 Accelerates the Migration and Invasion of Nonsmall Cell Lung Cancer In Vitro.
Total flavonoids from sea buckthorn ameliorates lipopolysaccharide/cigarette smoke-induced airway inflammation.
FAT1, a direct transcriptional target of E2F1, suppresses cell proliferation, migration and invasion in esophageal squamous cell carcinoma.
Discovery of a Pathogenic Variant rs139379666 (p. P2974L) in ATM for Breast Cancer Risk in Chinese Populations.
Role of SNHG7-miR-653-5p-STAT2 feedback loop in regulating neuroblastoma progression.
Exosomes from tendon stem cells promote injury tendon healing through balancing synthesis and degradation of the tendon extracellular matrix.
MANF regulates splenic macrophage differentiation in mice.
Migrasome formation is mediated by assembly of micron-scale tetraspanin macrodomains.
Migrasomes provide regional cues for organ morphogenesis during zebrafish gastrulation.
Identification of COMMD1 as a novel lamin A binding partner.
E3 ligase Fbw7 participates in oxidative stress‑induced myocardial cell injury via interacting with Mcl‑1.
Roseburia intestinalis supernatant ameliorates colitis induced in mice by regulating the immune response.
Progranulin Promotes Bleomycin-Induced Skin Sclerosis by Enhancing Transforming Growth Factor-β/Smad3 Signaling through Up-Regulation of Transforming Growth Factor-β Type I Receptor.
Fibronectin regulates the self-renewal of rabbit limbal epithelial stem cells by stimulating the Wnt11/Fzd7/ROCK non-canonical Wnt pathway.
MicroRNA-2053 overexpression inhibits the development and progression of hepatocellular carcinoma.
Ursolic acid isolated from Isodon excisoides induces apoptosis and inhibits invasion of GBC-SD gallbladder carcinoma cells.
Inducible LGALS3BP/90K activates antiviral innate immune responses by targeting TRAF6 and TRAF3 complex.
Sesterterpene MHO7 suppresses breast cancer cells as a novel estrogen receptor degrader.
MicroRNA-128-3p aggravates doxorubicin-induced liver injury by promoting oxidative stress via targeting Sirtuin-1.
Inhibitor of growth 4 (ING4) inhibits hypoxia-induced EMT by decreasing HIF-1α and snail in HK2 cells.
STAT3-induced long noncoding RNA LINC00668 promotes migration and invasion of non-small cell lung cancer via the miR-193a/KLF7 axis.
Ablation of core fucosylation attenuates the signal transduction via T cell receptor to suppress the T cell development.
Vasorin stimulates malignant progression and angiogenesis in glioma.
CircAGFG1 sponges miR-203 to promote EMT and metastasis of non-small-cell lung cancer by upregulating ZNF281 expression.
Extracellular Vesicles from Albumin-Induced Tubular Epithelial Cells Promote the M1 Macrophage Phenotype by Targeting Klotho.
LncRNA MEG3 acts a biomarker and regulates cell functions by targeting ADAR1 in colorectal cancer.
Berberine prevents stress-induced gut inflammation and visceral hypersensitivity and reduces intestinal motility in rats.
Isoliquiritigenin Suppresses E2-Induced Uterine Leiomyoma Growth through the Modulation of Cell Death Program and the Repression of ECM Accumulation.
A novel role for NFIA in restoring radiosensitivity in radioresistant NSCLC cells by downregulating the AKT and ERK pathways.
Mitochondrial NOS1 suppresses apoptosis in colon cancer cells through increasing SIRT3 activity.
TFEB-driven autophagy potentiates TGF-β induced migration in pancreatic cancer cells.
Generation of Human Fatty Livers Using Custom-Engineered Induced Pluripotent Stem Cells with Modifiable SIRT1 Metabolism.
Simvastatin inhibits the proliferation of HL-60 clone 15- derived eosinophils by inducing the arrest of the cell cycle in the G1/S phase.
Endoplasmic reticulum stress and proteasome pathway involvement in human podocyte injury with a truncated COL4A3 mutation.
CBX8 promotes tumorigenesis and confers radioresistance in esophageal squamous cell carcinoma cells through targeting APAF1.
Ibuprofen inhibited migration of skeletal muscle cells in association with downregulation of p130cas and CrkII expressions.
EXT1, Regulated by MiR-665, Promotes Cell Apoptosis via ERK1/2 Signaling Pathway in Acute Lymphoblastic Leukemia.
Identification of Glyceraldehyde-3-Phosphate Dehydrogenase Gene as an Alternative Safe Harbor Locus in Pig Genome.
SIV-Mediated Synaptic Dysfunction Is Associated with an Increase in Synapsin Site 1 Phosphorylation and Impaired PP2A Activity.
Nelfinavir and lenalidomide/dexamethasone in patients with lenalidomide-refractory multiple myeloma. A phase I/II Trial (SAKK 39/10).
Anti-high mobility group box-1 antibody attenuated vascular smooth muscle cell phenotypic switching and vascular remodelling after subarachnoid haemorrhage in rats.
Topoisomerase inhibitors promote cancer cell motility via ROS-mediated activation of JAK2-STAT1-CXCL1 pathway.
CircRNA CBL.11 suppresses cell proliferation by sponging miR-6778-5p in colorectal cancer.
Depletion of phosphatidylinositol 4-phosphate at the Golgi translocates K-Ras to mitochondria.
MiR-1197-3p regulates testosterone secretion in goat Leydig cells via targeting PPARGC1A.
CBX3/HP1γ promotes tumor proliferation and predicts poor survival in hepatocellular carcinoma.
Internalization Characterization of Si Nanorod with Camouflaged Cell Membrane Proteins Reveals ATXN2 as a Negative Regulator.
Combined Assembly and Targeted Integration of Multigene for Nitrogenase Biosynthetic Pathway in Saccharomyces cerevisiae.
CRABP2 regulates invasion and metastasis of breast cancer through hippo pathway dependent on ER status.
miR-504 suppresses mesenchymal phenotype of glioblastoma by directly targeting the FZD7-mediated Wnt-β-catenin pathway.
IMM-H007 improves heart function via reducing cardiac fibrosis.
The combination of lonafarnib and sorafenib induces cyclin D1 degradation via ATG3-mediated autophagic flux in hepatocellular carcinoma cells.
Induction of Fibroblast Senescence During Mouse Corneal Wound Healing.
Corneal Denervation Causes Epithelial Apoptosis Through Inhibiting NAD+ Biosynthesis.
p21-Activated kinase 3 promotes cancer stem cell phenotypes through activating the Akt-GSK3β-β-catenin signaling pathway in pancreatic cancer cells.
Retinol binding protein 4 mediates MEHP-induced glucometabolic abnormalities in HepG2 cells.
RUNX1 promotes tumour metastasis by activating the Wnt/β-catenin signalling pathway and EMT in colorectal cancer.
Amyotrophic lateral sclerosis-associated TDP-43 mutation Q331K prevents nuclear translocation of XRCC4-DNA ligase 4 complex and is linked to genome damage-mediated neuronal apoptosis.
Roseburia intestinalis inhibits oncostatin M and maintains tight junction integrity in a murine model of acute experimental colitis.
Adaptive EGF expression sensitizes pancreatic cancer cells to ionizing radiation through activation of the cyclin D1/P53/PARP pathway.
Expression patterns of C1ql4 and its cell-adhesion GPCR Bai3 in the murine testis and functional roles in steroidogenesis.
Treatment with metformin prevents myocardial ischemia-reperfusion injury via STEAP4 signaling pathway.
Comparative localization of cystathionine beta synthases and cystathionine gamma lyase in canine, non-human primate and human retina.
Type III interferon-induced CBFβ inhibits HBV replication by hijacking HBx.
5-(3,4-Difluorophenyl)-3-(6-methylpyridin-3-yl)-1,2,4-oxadiazole (DDO-7263), a novel Nrf2 activator targeting brain tissue, protects against MPTP-induced subacute Parkinson's disease in mice by inhibiting the NLRP3 inflammasome and protects PC12 cells against oxidative stress.
Role of p53 mediated miR-23a/CXCL12 pathway in osteogenic differentiation of bone mesenchymal stem cells on nanostructured titanium surfaces.
Ribociclib, a selective cyclin D kinase 4/6 inhibitor, inhibits proliferation and induces apoptosis of human cervical cancer in vitro and in vivo.
Adjudin synergizes with paclitaxel and inhibits cell growth and metastasis by regulating the sirtuin 3-Forkhead box O3a axis in human small-cell lung cancer.
Oxytocin Receptor Antagonists, Atosiban and Nolasiban, Inhibit Prostaglandin F(2α)-induced Contractions and Inflammatory Responses in Human Myometrium.
GTSE1 is involved in breast cancer progression in p53 mutation-dependent manner.
HAMP Downregulation Contributes to Aggressive Hepatocellular Carcinoma via Mechanism Mediated by Cyclin4-Dependent Kinase-1/STAT3 Pathway.
TMEM30A deficiency in endothelial cells impairs cell proliferation and angiogenesis.
FOXO1-regulated lncRNA LINC01197 inhibits pancreatic adenocarcinoma cell proliferation by restraining Wnt/β-catenin signaling.
Numb inhibits epithelial-mesenchymal transition via RBP-Jκ-dependent Notch1/PTEN/FAK signaling pathway in tongue cancer.
YAP Aggravates Inflammatory Bowel Disease by Regulating M1/M2 Macrophage Polarization and Gut Microbial Homeostasis.
Crosstalk Between Connexin32 and Mitochondrial Apoptotic Signaling Pathway Plays a Pivotal Role in Renal Ischemia Reperfusion-Induced Acute Kidney Injury.
Stabilized Peptide HDAC Inhibitors Derived from HDAC1 Substrate H3K56 for the Treatment of Cancer Stem-Like Cells In Vivo.
Benzoxazine monomer derived carbon dots as a broad-spectrum agent to block viral infectivity.
Proteomic analysis of mouse ovaries during the prepubertal stages.
Activation of GPR40 produces mechanical antiallodynia via the spinal glial interleukin-10/β-endorphin pathway.
CDK4/6 inhibitor palbociclib enhances the effect of pyrotinib in HER2-positive breast cancer.
Mild thermotherapy and hyperbaric oxygen enhance sensitivity of TMZ/PSi nanoparticles via decreasing the stemness in glioma.
The HMGA2-IMP2 Pathway Promotes Granulosa Cell Proliferation in Polycystic Ovary Syndrome.
Exosomal ephrinA2 derived from serum as a potential biomarker for prostate cancer.
P21-activated kinase 7 (PAK7) interacts with and activates Wnt/β-catenin signaling pathway in breast cancer.
TANK-Binding Kinase 1 (TBK1) Isoforms Negatively Regulate Type I Interferon Induction by Inhibiting TBK1-IRF3 Interaction and IRF3 Phosphorylation.
Core Fucosylation of the T Cell Receptor Is Required for T Cell Activation.
Fertility Enhancement but Premature Ovarian Failure in esr1-Deficient Female Zebrafish.
Bioinformatics Analysis Identifies p53 as a Candidate Prognostic Biomarker for Neuropathic Pain.
The Host Restriction Factor Interferon-Inducible Transmembrane Protein 3 Inhibits Vaccinia Virus Infection.
Tc17/IL-17A Up-Regulated the Expression of MMP-9 via NF-κB Pathway in Nasal Epithelial Cells of Patients With Chronic Rhinosinusitis.
Sesamin Protects the Femoral Head From Osteonecrosis by Inhibiting ROS-Induced Osteoblast Apoptosis in Rat Model.
Lactobacillus rhamnosus GR-1 Ameliorates Escherichia coli-Induced Activation of NLRP3 and NLRC4 Inflammasomes With Differential Requirement for ASC.
Effective Amelioration of Liver Fibrosis Through Lentiviral Vector Carrying Toxoplasma gondii gra15(II) in Murine Model.
MicroRNA-181a Functions as an Oncogene in Gastric Cancer by Targeting Caprin-1.
DEAD-Box Helicase 5 Interacts With Transcription Factor 12 and Promotes the Progression of Osteosarcoma by Stimulating Cell Cycle Progression.
Coagulation Factor X Regulated by CASC2c Recruited Macrophages and Induced M2 Polarization in Glioblastoma Multiforme.
Latent Membrane Protein 1 of Epstein-Barr Virus Promotes RIG-I Degradation Mediated by Proteasome Pathway.
Invalidation of Microsomal Prostaglandin E Synthase-1 (mPGES-1) Reduces Diet-Induced Low-Grade Inflammation and Adiposity.
Non-Hematopoietic MLKL Protects Against Salmonella Mucosal Infection by Enhancing Inflammasome Activation.
Evaluation of Oral Antiretroviral Drugs in Mice With Metabolic and Neurologic Complications.
Efficient delivery of nucleic acid molecules into skin by combined use of microneedle roller and flexible interdigitated electroporation array.
OVOL2 links stemness and metastasis via fine-tuning epithelial-mesenchymal transition in nasopharyngeal carcinoma.
S6K1 phosphorylation-dependent degradation of Mxi1 by β-Trcp ubiquitin ligase promotes Myc activation and radioresistance in lung cancer.
Long noncoding RNA CCAT2 is activated by E2F1 and exerts oncogenic properties by interacting with PTTG1 in pituitary adenomas.
Dengue Virus Infects Primary Human Hair Follicle Dermal Papilla Cells.
Neurodegeneration-associated FUS is a novel regulator of circadian gene expression.
Does the Genetic Feature of the Chinese Tree Shrew (Tupaia belangeri chinensis) Support Its Potential as a Viable Model for Alzheimer's Disease Research?
Huperzine A attenuates nonalcoholic fatty liver disease by regulating hepatocyte senescence and apoptosis: an in vitro study.
miRNA-1290 Promotes Aggressiveness in Pancreatic Ductal Adenocarcinoma by Targeting IKK1.
FGFR2 Promotes Gastric Cancer Progression by Inhibiting the Expression of Thrombospondin4 via PI3K-Akt-Mtor Pathway.
Activator Protein-2β Promotes Tumor Growth and Predicts Poor Prognosis in Breast Cancer.
HSP70/HSP90-Organizing Protein Contributes to Gastric Cancer Progression in an Autocrine Fashion and Predicts Poor Survival in Gastric Cancer.
Asiatic Acid (AA) Sensitizes Multidrug-Resistant Human Lung Adenocarcinoma A549/DDP Cells to Cisplatin (DDP) via Downregulation of P-Glycoprotein (MDR1) and Its Targets.
17β-Estradiol inhibits intervertebral disc degeneration by down-regulating MMP-3 and MMP-13 and up-regulating type II collagen in a rat model.
Neuroprotective Effects of Magnesium Lithospermate B against Subarachnoid Hemorrhage in Rats.
NR4A1 is Involved in Fibrogenesis in Ovarian Endometriosis.
Ethyl Pyruvate Attenuates CaCl2-Induced Tubular Epithelial Cell Injury by Inhibiting Autophagy and Inflammatory Responses.
Inhibition of Autophagy Attenuated Ethylene Glycol Induced Crystals Deposition and Renal Injury in a Rat Model of Nephrolithiasis.
Renal sympathetic denervation lowers arterial pressure in canines with obesity-induced hypertension by regulating GAD65 and AT(1)R expression in rostral ventrolateral medulla.
MST1 Suppression Reduces Early Brain Injury by Inhibiting the NF-κB/MMP-9 Pathway after Subarachnoid Hemorrhage in Mice.
Hypoxia Enhances Fusion of Oral Squamous Carcinoma Cells and Epithelial Cells Partly via the Epithelial-Mesenchymal Transition of Epithelial Cells.
Increased Autophagy Enhances the Resistance to Tumor Necrosis Factor-Alpha Treatment in Rheumatoid Arthritis Human Fibroblast-Like Synovial Cell.
Hydrogen Sulfide Alleviates Acute Myocardial Ischemia Injury by Modulating Autophagy and Inflammation Response under Oxidative Stress.
3-(1H-Benzo[d]imidazol-6-yl)-5-(4-fluorophenyl)-1,2,4-oxadiazole (DDO7232), a Novel Potent Nrf2/ARE Inducer, Ameliorates DSS-Induced Murine Colitis and Protects NCM460 Cells against Oxidative Stress via ERK1/2 Phosphorylation.
High Expression of ITGA3 Promotes Proliferation and Cell Cycle Progression and Indicates Poor Prognosis in Intrahepatic Cholangiocarcinoma.
Selenoprotein S Attenuates Tumor Necrosis Factor-α-Induced Dysfunction in Endothelial Cells.
RNF138 confers cisplatin resistance in gastric cancer cells via activating Chk1 signaling pathway.
MicroRNA-133b/EGFR axis regulates esophageal squamous cell carcinoma metastases by suppressing anoikis resistance and anchorage-independent growth.
Paraoxonase 3 is involved in the multi-drug resistance of esophageal cancer.
The lncRNA CCAT1 upregulates TGFβR1 via sponging miR-490-3p to promote TGFβ1-induced EMT of ovarian cancer cells.
Downregulation of MiR-203a Disinhibits Bmi1 and Promotes Growth and Proliferation of Keratinocytes in Cholesteatoma.
Amelioration of hepatic steatosis is associated with modulation of gut microbiota and suppression of hepatic miR-34a in Gynostemma pentaphylla (Thunb.) Makino treated mice.
Overexpression of Toll-like Receptor 4-linked Mitogen-activated Protein Kinase Signaling Contributes to Internalization of Escherichia coli in Sheep.
PARI functions as a new transcriptional target of FOXM1 involved in gastric cancer development.
Engagement of circular RNA HECW2 in the nonautophagic role of ATG5 implicated in the endothelial-mesenchymal transition.
Autosomal dominant retinitis pigmentosa-associated gene PRPF8 is essential for hypoxia-induced mitophagy through regulating ULK1 mRNA splicing.
Combined inhibition of autophagy and Nrf2 signaling augments bortezomib-induced apoptosis by increasing ROS production and ER stress in pancreatic cancer cells.
Dexmedetomidine attenuates the propofol-induced long-term neurotoxicity in the developing brain of rats by enhancing the PI3K/Akt signaling pathway.
Wenyang Huazhuo Tongluo formula inhibits fibrosis via suppressing Wnt/β-catenin signaling pathway in a Bleomycin-induced systemic sclerosis mouse model.
Notch inhibitor can attenuate apparent diffusion coefficient and improve neurological function through downregulating NOX2-ROS in severe traumatic brain injury.
Realgar, a traditional Chinese medicine, induces apoptosis of HPV16-positive cervical cells through a HPV16 E7-related pathway.
Zoledronate inhibits fibroblasts' proliferation and activation via targeting TGF-β signaling pathway.
Gestational Exposure to Particulate Matter 2.5 (PM(2.5)) Leads to Spatial Memory Dysfunction and Neurodevelopmental Impairment in Hippocampus of Mice Offspring.
EDIL3 depletion suppress epithelial-mesenchymal transition of lens epithelial cells via transforming growth factor β pathway.
Endothelial Monocyte-Activating Polypeptide-II Induces BNIP3-Mediated Mitophagy to Enhance Temozolomide Cytotoxicity of Glioma Stem Cells via Down-Regulating MiR-24-3p.
Brevilin A promotes oxidative stress and induces mitochondrial apoptosis in U87 glioblastoma cells.
MiR-429 Regulated by Endothelial Monocyte Activating Polypeptide-II (EMAP-II) Influences Blood-Tumor Barrier Permeability by Inhibiting the Expressions of ZO-1, Occludin and Claudin-5.
STAT3 induces colorectal carcinoma progression through a novel miR-572-MOAP-1 pathway.
Hypoxic Preconditioning Maintains GLT-1 Against Transient Global Cerebral Ischemia Through Upregulating Cx43 and Inhibiting c-Src.
Cosmosiin Increases ADAM10 Expression via Mechanisms Involving 5'UTR and PI3K Signaling.
Transcriptional Repression of p53 by PAX3 Contributes to Gliomagenesis and Differentiation of Glioma Stem Cells.
Characteristics of Sinus Fungus Ball: A Unique Form of Rhinosinusitis.
GPX3 suppresses tumor migration and invasion via the FAK/AKT pathway in esophageal squamous cell carcinoma.
NADH protect against radiation enteritis by enhancing autophagy and inhibiting inflammation through PI3K/AKT pathway.
Reduced selenium-binding protein 1 correlates with a poor prognosis in intrahepatic cholangiocarcinoma and promotes the cell epithelial-mesenchymal transition.
miR-125a-5p suppresses colorectal cancer progression by targeting VEGFA.
Non-coding RNA NEAT1/miR-214-3p contribute to doxorubicin resistance of urothelial bladder cancer preliminary through the Wnt/β-catenin pathway.
Inhibition of Cathepsins B Induces Neuroprotection Against Secondary Degeneration in Ipsilateral Substantia Nigra After Focal Cortical Infarction in Adult Male Rats.
The transcription factor C/EBP α controls the role of cystatin F during the differentiation of monocytes to macrophages.
Comparative proteomics reveals the neurotoxicity mechanism of ER stressors tunicamycin and dithiothreitol.
Gemcitabine induces apoptosis and autophagy via the AMPK/mTOR signaling pathway in pancreatic cancer cells.
Sex differences in the effect of cannabinoid type 1 receptor deletion on locus coeruleus-norepinephrine neurons and corticotropin releasing factor-mediated responses.
The suppressive effect of soluble Klotho on fibroblastic growth factor 23 synthesis in UMR-106 osteoblast-like cells.
Downregulation of TRIM58 expression is associated with a poor patient outcome and enhances colorectal cancer cell invasion.
Interferon Gamma Inhibits CXCL8-Induced Proliferation and Migration of Pancreatic Cancer BxPC-3 Cell Line via a RhoGDI2/Rac1/NF-κB Signaling Pathway.
Selective Actionable and Druggable Protein Kinases Drive the Progression of Neuroendocrine Prostate Cancer.
Activation of STAT3 and Bcl-2 and reduction of reactive oxygen species (ROS) promote radioresistance in breast cancer and overcome of radioresistance with niclosamide.
IL-6 increases podocyte motility via MLC-mediated focal adhesion impairment and cytoskeleton disassembly.
Epigenetic regulation of megakaryocytic and erythroid differentiation by PHF2 histone demethylase.
The oncogenic potentials and diagnostic significance of long non-coding RNA LINC00310 in breast cancer.
Stromal expression of JNK1 and VDR is associated with the prognosis of esophageal squamous cell carcinoma.
Protein arginine methyltransferase 5-mediated epigenetic silencing of IRX1 contributes to tumorigenicity and metastasis of gastric cancer.
UNBS5162 inhibits proliferation of human melanoma cells by inducing apoptosis via the PI3K/Akt pathway.
Adenoviral vector-induced silencing of RGMa attenuates blood-brain barrier dysfunction in a rat model of MCAO/reperfusion.
Role of hepatoma-derived growth factor in promoting de novo lipogenesis and tumorigenesis in hepatocellular carcinoma.
Long noncoding RNA LINC00460 targets miR-539/MMP-9 to promote meningioma progression and metastasis.
USP4 positively regulates RLR-induced NF-κB activation by targeting TRAF6 for K48-linked deubiquitination and inhibits enterovirus 71 replication.
FOXC1 induces cancer stem cell-like properties through upregulation of beta-catenin in NSCLC.
De Novo Mutations of CCNK Cause a Syndromic Neurodevelopmental Disorder with Distinctive Facial Dysmorphism.
LINC00470 Coordinates the Epigenetic Regulation of ELFN2 to Distract GBM Cell Autophagy.
Cationic Polymeric Nanoparticle Delivering CCR2 siRNA to Inflammatory Monocytes for Tumor Microenvironment Modification and Cancer Therapy.
A new meroterpenoid functions as an anti-tumor agent in hepatoma cells by downregulating mTOR activation and inhibiting EMT.
Long noncoding RNA MIR31HG inhibits hepatocellular carcinoma proliferation and metastasis by sponging microRNA-575 to modulate ST7L expression.
Covalent inhibitors of EGFR family protein kinases induce degradation of human Tribbles 2 (TRIB2) pseudokinase in cancer cells.
Distinct multilevel misregulations of Parkin and PINK1 revealed in cell and animal models of TDP-43 proteinopathy.
Targeting Epigenetic Crosstalk as a Therapeutic Strategy for EZH2-Aberrant Solid Tumors.
Anti-breast-Cancer Activity Exerted by β-Sitosterol-d-glucoside from Sweet Potato via Upregulation of MicroRNA-10a and via the PI3K-Akt Signaling Pathway.
Postinfarction Hearts Are Protected by Premature Senescent Cardiomyocytes Via GATA 4-Dependent CCN 1 Secretion.
IL-13 and IL-13Rα1 are overexpressed in extranodal natural killer/T cell lymphoma and mediate tumor cell proliferation.
Non-canonical NF-κB Antagonizes STING Sensor-Mediated DNA Sensing in Radiotherapy.
Mesenchymal stem cells alleviate experimental autoimmune cholangitis through immunosuppression and cytoprotective function mediated by galectin-9.
TPC2 mediates autophagy progression and extracellular vesicle secretion in cancer cells.
Rab7 empowers renal tubular epithelial cells with autophagy-mediated protection against albumin-induced injury.
miR-203 Suppresses Bladder Cancer Cell Growth and Targets Twist1.
Human Cytomegalovirus Immediate Early 1 Protein Causes Loss of SOX2 from Neural Progenitor Cells by Trapping Unphosphorylated STAT3 in the Nucleus.
The developmental transcription factor IRF6 attenuates ABCG2 gene expression and distinctively reverses stemness phenotype in nasopharyngeal carcinoma.
Spinal interleukin-10 produces antinociception in neuropathy through microglial β-endorphin expression, separated from antineuroinflammation.
MALAT1 promotes the colorectal cancer malignancy by increasing DCP1A expression and miR203 downregulation.
MiR-616-3p modulates cell proliferation and migration through targeting tissue factor pathway inhibitor 2 in preeclampsia.
The effects of HAP and macrophage cells to the expression of inflammatory factors and apoptosis in HK-2 cells of vitro co-cultured system.
Effects of NMDAR Antagonist on the Regulation of P-MARCKS Protein to Aβ(1-42) Oligomers Induced Neurotoxicity.
GPR40 modulates epileptic seizure and NMDA receptor function.
Erythropoietin-producing hepatocellular A7 triggering ovulation indicates a potential beneficial role for polycystic ovary syndrome.
SIRT5 deacylates metabolism-related proteins and attenuates hepatic steatosis in ob/ob mice.
miR-25 Promotes Melanoma Progression by regulating RNA binding motif protein 47.
Histone Deacetylase 3 Inhibitor Suppresses Hepatitis C Virus Replication by Regulating Apo-A1 and LEAP-1 Expression.
Histone deacetylase inhibitor suberoylanilide hydroxamic acid alleviates liver fibrosis by suppressing the transforming growth factor-β1 signal pathway.
Study on the expression of p53 and MMP-2 in patients with lung cancer after interventional therapy.
Subarachnoid hemorrhage enhances the expression of TDP-43 in the brain of experimental rats and human subjects.
Genistein sensitizes glioblastoma cells to carbon ions via inhibiting DNA-PKcs phosphorylation and subsequently repressing NHEJ and delaying HR repair pathways.
MicroRNA-23a-5p promotes atherosclerotic plaque progression and vulnerability by repressing ATP-binding cassette transporter A1/G1 in macrophages.
Long non-coding RNA LINC00222 regulates GSK3β activity and promotes cell apoptosis in lung adenocarcinoma.
MicroRNA-139-3p regulates osteoblast differentiation and apoptosis by targeting ELK1 and interacting with long noncoding RNA ODSM.
The effects of lncRNA MALAT1 on proliferation, invasion and migration in colorectal cancer through regulating SOX9.
Apigenin suppresses PD-L1 expression in melanoma and host dendritic cells to elicit synergistic therapeutic effects.
Salvianolic Acid B-Alleviated Angiotensin II Induces Cardiac Fibrosis by Suppressing NF-κB Pathway In Vitro.
MicroRNA-9 modified bone marrow-derived mesenchymal stem cells (BMSCs) repair severe acute pancreatitis (SAP) via inducing angiogenesis in rats.
Up-regulated miR-133a orchestrates epithelial-mesenchymal transition of airway epithelial cells.
Neuroinflammation is induced by tongue-instilled ZnO nanoparticles via the Ca(2+)-dependent NF-κB and MAPK pathways.
Enhanced anti-obesity effects of bacterial cellulose combined with konjac glucomannan in high-fat diet-fed C57BL/6J mice.
Immune Activation of RAW264.7 Macrophages by Low Molecular Weight Fucoidan Extracted from New Zealand Undaria pinnatifida.
miR-365 Suppresses Cholangiocarcinoma Cell Proliferation and Induces Apoptosis by Targeting E2F2.
Cd induces G2/M cell cycle arrest by up-regulating miR-133b via directly targeting PPP2R2D in L02 hepatocytes.
Biased antagonism of CXCR4 avoids antagonist tolerance.
GAPDH rs1136666 SNP indicates a high risk of Parkinson's disease.
PARP1 interacts with STAT3 and retains active phosphorylated-STAT3 in nucleus during pathological myocardial hypertrophy.
The Age-dependent Elevation of miR-335-3p Leads to Reduced Cholesterol and Impaired Memory in Brain.
Identification of the UBA2-WTIP fusion gene in acute myeloid leukemia.
Role of p62/SQSTM1 in lipopolysaccharide (LPS)-induced mucus hypersecretion in bronchial epithelial cells.
Bowman‒Birk Inhibitor Suppresses Herpes Simplex Virus Type 2 Infection of Human Cervical Epithelial Cells.
Mechanism of piR-DQ590027/MIR17HG regulating the permeability of glioma conditioned normal BBB.
Isopsoralen Enhanced Osteogenesis by Targeting AhR/ERα.
Deleting MyD88 signaling in myeloid cells promotes development of adenocarcinomas of the colon.
Alantolactone induces apoptosis and improves chemosensitivity of pancreatic cancer cells by impairment of autophagy-lysosome pathway via targeting TFEB.
Regulation of osteogenesis by micro/nano hierarchical titanium surfaces through a Rock-Wnt5a feedback loop.
The protective effect of melatonin on brain ischemia and reperfusion in rats and humans: In vivo assessment and a randomized controlled trial.
The sialyltransferase ST3Gal3 facilitates the receptivity of the uterine endometrium in vitro and in vivo.
RNA interference of long noncoding RNA HOTAIR suppresses autophagy and promotes apoptosis and sensitivity to cisplatin in oral squamous cell carcinoma.
HMGB1 knock-down promoting tumor cells viability and arrest pro-apoptotic proteins via Stat3/NFκB in HepG2 cells.
KLF5 promotes the tumorigenesis and metastatic potential of thyroid cancer cells through the NF-κB signaling pathway.
Microtubule associated protein 4 phosphorylation leads to pathological cardiac remodeling in mice.
METTL3-mediated N(6)-methyladenosine mRNA modification enhances long-term memory consolidation.
miR-153 inhibits the migration and the tube formation of endothelial cells by blocking the paracrine of angiopoietin 1 in breast cancer cells.
Silencing of rhomboid domain containing 1 to inhibit the metastasis of human breast cancer cells in vitro.
Deficiency in augmenter of liver regeneration accelerates liver fibrosis by promoting migration of hepatic stellate cell.
Boron Affects the Development of the Kidney Through Modulation of Apoptosis, Antioxidant Capacity, and Nrf2 Pathway in the African Ostrich Chicks.
Cantharidin inhibits melanoma cell proliferation via the miR‑21‑mediated PTEN pathway.
Protective effects of α‑2‑macroglobulin on human bone marrow mesenchymal stem cells in radiation injury.
Hepatitis B virus X protein promotes epithelial-mesenchymal transition and metastasis in hepatocellular carcinoma cell line HCCLM3 by targeting HMGA2.
METTL3 promotes ovarian carcinoma growth and invasion through the regulation of AXL translation and epithelial to mesenchymal transition.
Blocking LINC00152 suppresses glioblastoma malignancy by impairing mesenchymal phenotype through the miR-612/AKT2/NF-κB pathway.
Activation of α7 nicotinic acetylcholine receptor alleviates Aβ(1-42)-induced neurotoxicity via downregulation of p38 and JNK MAPK signaling pathways.
Pathological cyclic strain promotes proliferation of vascular smooth muscle cells via the ACTH/ERK/STAT3 pathway.
Toll-like receptor 4 shRNA attenuates lipopolysaccharide-induced epithelial-mesenchymal transition of intrahepatic biliary epithelial cells in rats.
miR-146b promotes cell proliferation and increases chemosensitivity, but attenuates cell migration and invasion via FBXL10 in ovarian cancer.
Evaluation of a Potential Clinical Significant Drug-Drug Interaction between Digoxin and Bupropion in Cynomolgus Monkeys.
Breed Differences in Pig Liver Esterase (PLE) between Tongcheng (Chinese Local Breed) and Large White Pigs.
Synergetic and Antagonistic Molecular Effects Mediated by the Feedback Loop of p53 and JNK between Saikosaponin D and SP600125 on Lung Cancer A549 Cells.
Vasculogenic mimicry formation in EBV-associated epithelial malignancies.
Abnormally elevated USP37 expression in breast cancer stem cells regulates stemness, epithelial-mesenchymal transition and cisplatin sensitivity.
The Mitochondrial Apoptotic Effectors BAX/BAK Activate Caspase-3 and -7 to Trigger NLRP3 Inflammasome and Caspase-8 Driven IL-1β Activation.
Aspergillus fumigatus phospholipase D may enhance reactive oxygen species production by accumulation of histone deacetylase 6.
Tetrachlorobenzoquinone-Induced Nrf2 Confers Neuron-like PC12 Cells Resistance to Endoplasmic Reticulum Stress via Regulating Glutathione Synthesis and Protein Thiol Homeostasis.
PJA1 Coordinates with the SMC5/6 Complex To Restrict DNA Viruses and Episomal Genes in an Interferon-Independent Manner.
Up-regulation of LncRNA MEG3 inhibits cell migration and invasion and enhances cisplatin chemosensitivity in bladder cancer cells.
CHCHD2 accumulates in distressed mitochondria and facilitates oligomerization of CHCHD10.
Hemopexin reduces blood-brain barrier injury and protects synaptic plasticity in cerebral ischemic rats by promoting EPCs through the HO-1 pathway.
Tannic acid directly targets pyruvate kinase isoenzyme M2 to attenuate colon cancer cell proliferation.
Upregulation of circ-UBAP2 predicts poor prognosis and promotes triple-negative breast cancer progression through the miR-661/MTA1 pathway.
Astragaloside exerts anti-photoaging effects in UVB-induced premature senescence of rat dermal fibroblasts through enhanced autophagy.
Expression of programmed cell death protein 1 (PD-1) and indoleamine 2,3-dioxygenase (IDO) in the tumor microenvironment and in tumor-draining lymph nodes of breast cancer.
Progranulin promotes lymphangiogenesis through VEGF-C and is an independent risk factor in human esophageal cancers.
MicroRNA-181c promotes Th17 cell differentiation and mediates experimental autoimmune encephalomyelitis.
Resveratrol Improves Muscle Atrophy by Modulating Mitochondrial Quality Control in STZ-Induced Diabetic Mice.
Follicle-stimulating hormone enhances hepatic gluconeogenesis by GRK2-mediated AMPK hyperphosphorylation at Ser485 in mice.
CEACAM1 resists hypoxia-induced inhibition of tube formation of human dermal lymphatic endothelial cells.
Ultrasound Irradiation Combined with Hepatocyte Growth Factor Accelerate the Hepatic Differentiation of Human Bone Marrow Mesenchymal Stem Cells.
Effect of placental sex hormone-binding globulin single nucleotide polymorphism rs6259 on protein and function in gestational diabetes mellitus.
Identification of Functional Thyroid Stimulating Hormone Receptor and TSHR Gene Mutations in Hepatocellular Carcinoma.
The E3 ubiquitin ligase Triad1 influences development of Mll-Ell-induced acute myeloid leukemia.
LncRNA-PVT1 promotes pancreatic cancer cells proliferation and migration through acting as a molecular sponge to regulate miR-448.
Antagonism of cortistatin against cyclosporine-induced apoptosis in rat myocardial cells and its effect on myocardial apoptosis gene expression.
PVT1 regulates the malignant behaviors of human glioma cells by targeting miR-190a-5p and miR-488-3p.
FTO promotes SREBP1c maturation and enhances CIDEC transcription during lipid accumulation in HepG2 cells.
Targeting Polo-like Kinase 1 by a Novel Pyrrole-Imidazole Polyamide-Hoechst Conjugate Suppresses Tumor Growth In Vivo.
Liraglutide improves hepatic insulin resistance via the canonical Wnt signaling pathway.
Local intra‑articular injection of vascular endothelial growth factor accelerates articular cartilage degeneration in rat osteoarthritis model.
Cantharidin suppresses cell growth and migration, and activates autophagy in human non-small cell lung cancer cells.
M2-specific reduction of CD1d switches NKT cell-mediated immune responses and triggers metaflammation in adipose tissue.
Cardioprotection of CAPE-oNO(2) against myocardial ischemia/reperfusion induced ROS generation via regulating the SIRT1/eNOS/NF-κB pathway in vivo and in vitro.
The glucagon-like peptide-1 (GLP-1) analog liraglutide attenuates renal fibrosis.
Diallyl Trisulfide inhibits breast cancer stem cells via suppression of Wnt/β-catenin pathway.
Activation of AMPK by simvastatin inhibited breast tumor angiogenesis via impeding HIF-1α-induced pro-angiogenic factor.
Perfluorooctane sulfonate mediates secretion of IL-1β through PI3K/AKT NF-кB pathway in astrocytes.
Chromosome Segregation Is Biased by Kinetochore Size.
CysLTR1 Blockage Ameliorates Liver Injury Caused by Aluminum-Overload via PI3K/AKT/mTOR-Mediated Autophagy Activation in Vivo and in Vitro.
Interleukin-23 promotes the migration and invasion of gastric cancer cells by inducing epithelial-to-mesenchymal transition via the STAT3 pathway.
Dysregulation of tristetraprolin and human antigen R promotes gastric cancer progressions partly by upregulation of the high-mobility group box 1.
The Novel miRNA N-72 Regulates EGF-Induced Migration of Human Amnion Mesenchymal Stem Cells by Targeting MMP2.
Resting T cells are hypersensitive to DNA damage due to defective DNA repair pathway.
Dietary supplementation with ketoacids protects against CKD-induced oxidative damage and mitochondrial dysfunction in skeletal muscle of 5/6 nephrectomised rats.
Identification of Selective, Cell Active Inhibitors of Protein Arginine Methyltransferase 5 through Structure-Based Virtual Screening and Biological Assays.
MiR-29c reduces the cisplatin resistance of non-small cell lung cancer cells by negatively regulating the PI3K/Akt pathway.
[Role of allograft inflammatory factor-1 in regulating the proliferation, migration and apoptosis of colorectal cancer cells].
Dexmedetomidine reduces ventilator-induced lung injury (VILI) by inhibiting Toll-like receptor 4 (TLR4)/nuclear factor (NF)-κB signaling pathway.
Apolipoprotein C1 promotes prostate cancer cell proliferation in vitro.
Long-term exposure to low-dose Haemophilus influenzae during allergic airway disease drives a steroid-resistant neutrophilic inflammation and promotes airway remodeling.
Rotenone ameliorates chronic renal injury caused by acute ischemia/reperfusion.
Single-Cell Analysis of the Impact of Host Cell Heterogeneity on Infection with Foot-and-Mouth Disease Virus.
Autophagic degradation of caveolin-1 promotes liver sinusoidal endothelial cells defenestration.
KIF4A facilitates cell proliferation via induction of p21-mediated cell cycle progression and promotes metastasis in colorectal cancer.
Dkk3 dependent transcriptional regulation controls age related skeletal muscle atrophy.
Inhibition of transient receptor potential melastatin 8 alleviates airway inflammation and remodeling in a murine model of asthma with cold air stimulus.
Rewiring of Glutamine Metabolism Is a Bioenergetic Adaptation of Human Cells with Mitochondrial DNA Mutations.
The Dopamine Receptor D3 Regulates Lipopolysaccharide-Induced Depressive-Like Behavior in Mice.
Glial fibrillary acidic protein promoter determines transgene expression in satellite glial cells following intraganglionic adeno-associated virus delivery in adult rats.
Periostin promotes migration, proliferation, and differentiation of human periodontal ligament mesenchymal stem cells.
Combination Treatment with Methylene Blue and Hypothermia in Global Cerebral Ischemia.
Role of the hippocampal 5-HT1A receptor-mediated cAMP/PKA signalling pathway in sevoflurane-induced cognitivedysfunction in aged rats.
Baicalin protects H9c2 cardiomyocytes against hypoxia/reoxygenation-induced apoptosis and oxidative stress through activation of mitochondrial aldehyde dehydrogenase 2.
Analysis of the oncogene BRAF mutation and the correlation of the expression of wild-type BRAF and CREB1 in endometriosis.
Tumor-suppressive miRNA-135a inhibits breast cancer cell proliferation by targeting ELK1 and ELK3 oncogenes.
miR-141 inhibits prostatic cancer cell proliferation and migration, and induces cell apoptosis via targeting of RUNX1.
TAp63 is correlated with chronic inflammation in patients with newly diagnosed type 2 diabetes mellitus.
Identification of a novel compound targeting the nuclear export of influenza A virus nucleoprotein.
Analysis of the association of the expression of KiSS-1 in colorectal cancer tissues with the pathology and prognosis.
miR-98 inhibits cell proliferation and induces cell apoptosis by targeting MAPK6 in HUVECs.
Type I IFN augments IL-27-dependent TRIM25 expression to inhibit HBV replication.
MAD2L2 inhibits colorectal cancer growth by promoting NCOA3 ubiquitination and degradation.
Protein kinase C epsilon mediates the inhibition of angiotensin II on the slowly activating delayed-rectifier potassium current through channel phosphorylation.
Lanthanum chloride impairs memory in rats by disturbing the glutamate-glutamine cycle and over-activating NMDA receptors.
The expression of the new epididymal luminal protein of PDZ domain containing 1 is decreased in asthenozoospermia.
MiR-134, epigenetically silenced in gliomas, could mitigate the malignant phenotype by targeting KRAS.
SFTS phlebovirus promotes LC3-II accumulation and nonstructural protein of SFTS phlebovirus co-localizes with autophagy proteins.
Inhibition of HIV early replication by the p53 and its downstream gene p21.
Overexpression of zinc-α2-glycoprotein suppressed seizures and seizure-related neuroflammation in pentylenetetrazol-kindled rats.
The transcriptional profiles and functional implications of long non-coding RNAs in the unfolded protein response.
Regulation by FSH of the dynamic expression of retinol-binding protein 4 in the mouse ovary.
Transmembrane E3 ligase RNF183 mediates ER stress-induced apoptosis by degrading Bcl-xL.
Pin1 mediates Aβ(42)-induced dendritic spine loss.
PIWIL1/piRNA-DQ593109 Regulates the Permeability of the Blood-Tumor Barrier via the MEG3/miR-330-5p/RUNX3 Axis.
circ-SHKBP1 Regulates the Angiogenesis of U87 Glioma-Exposed Endothelial Cells through miR-544a/FOXP1 and miR-379/FOXP2 Pathways.
Zc3h13 Regulates Nuclear RNA m(6)A Methylation and Mouse Embryonic Stem Cell Self-Renewal.
In vitro study of FUZ as a novel potential therapeutic target in non-small-cell lung cancer.
Cigarette smoke stimulates the stemness of renal cancer stem cells via Sonic Hedgehog pathway.
Structural Basis for the Inhibition of Host Gene Expression by Porcine Epidemic Diarrhea Virus nsp1.
LncRNA UCA1 attenuates autophagy-dependent cell death through blocking autophagic flux under arsenic stress.
Cell division cycle 7 is a potential therapeutic target in oral squamous cell carcinoma and is regulated by E2F1.
Propranolol prevents liver cirrhosis by inhibiting hepatic stellate cell activation mediated by the PDGFR/Akt pathway.
Setd7 and its contribution to Boron-induced bone regeneration in Boron-mesoporous bioactive glass scaffolds.
Clinical significance of combined detection of interleukin-6 and tumour markers in lung cancer.
Oestrogen receptor β5 and epidermal growth factor receptor synergistically promote lung cancer progression.
Mutant KRAS promotes liver metastasis of colorectal cancer, in part, by upregulating the MEK-Sp1-DNMT1-miR-137-YB-1-IGF-IR signaling pathway.
Sequestosome 1 protects esophageal squamous carcinoma cells from apoptosis via stabilizing SKP2 under serum starvation condition.
Abberent expression of NOR1 protein in tumor associated macrophages contributes to the development of DEN-induced hepatocellular carcinoma.
S1PR3 is essential for phosphorylated fingolimod to protect astrocytes against oxygen-glucose deprivation-induced neuroinflammation via inhibiting TLR2/4-NFκB signalling.
Correlation between autophagy levels in peripheral blood mononuclear cells and clinical parameters in patients with chronic obstructive pulmonary disease.
Osteogenesis potential of different titania nanotubes in oxidative stress microenvironment.
Protective effect of dioscin against doxorubicin-induced cardiotoxicity via adjusting microRNA-140-5p-mediated myocardial oxidative stress.
Downregulation of FOXP2 promotes breast cancer migration and invasion through TGFβ/SMAD signaling pathway.
Excessive endoplasmic reticulum stress and decreased neuroplasticity-associated proteins in prefrontal cortex of obese rats and the regulatory effects of aerobic exercise.
Cognitive-enhancing effect of polysaccharides from Flammulina velutipes on Alzheimer's disease by compatibilizing with ginsenosides.
Krüppel-like factor 4 promotes c-Met amplification-mediated gefitinib resistance in non-small-cell lung cancer.
Effects of cholecalciferol cholesterol emulsion on renal fibrosis and aquaporin 2 and 4 in mice with unilateral ureteral obstruction.
Acetylation of oxidized base repair-initiating NEIL1 DNA glycosylase required for chromatin-bound repair complex formation in the human genome increases cellular resistance to oxidative stress.
The natural compound GL22, isolated from Ganoderma mushrooms, suppresses tumor growth by altering lipid metabolism and triggering cell death.
Metformin ameliorates TGF-β1-induced osteoblastic differentiation of human aortic valve interstitial cells by inhibiting β-catenin signaling.
HEV ORF3 downregulates TLR7 to inhibit the generation of type I interferon via impairment of multiple signaling pathways.
Integrin αvβ3-associated DAAM1 is essential for collagen-induced invadopodia extension and cell haptotaxis in breast cancer cells.
Traditional Chinese medication Tongxinluo attenuates apoptosis in ox-LDL-stimulated macrophages by enhancing Beclin-1-induced autophagy.
Carbon monoxide-releasing molecule-3 protects against ischemic stroke by suppressing neuroinflammation and alleviating blood-brain barrier disruption.
4EHP-independent repression of endogenous mRNAs by the RNA-binding protein GIGYF2.
Deer thymosin beta 10 functions as a novel factor for angiogenesis and chondrogenesis during antler growth and regeneration.
Oxidative stress-mediated autophagic cell death participates in the neurotoxic effect on SH-SY5Y cells induced by excessive iodide.
SPG6 supports development of acute myeloid leukemia by regulating BMPR2-Smad-Bcl-2/Bcl-xl signaling.
PHF5A Epigenetically Inhibits Apoptosis to Promote Breast Cancer Progression.
RBM4 Modulates Radial Migration via Alternative Splicing of Dab1 during Cortex Development.
Reversal of reserpine-induced depression and cognitive disorder in zebrafish by sertraline and Traditional Chinese Medicine (TCM).
Exosomes released by hepatocarcinoma cells endow adipocytes with tumor-promoting properties.
Downregulation of HS6ST2 by miR-23b-3p enhances matrix degradation through p38 MAPK pathway in osteoarthritis.
BAI1 Suppresses Medulloblastoma Formation by Protecting p53 from Mdm2-Mediated Degradation.
miR-675 promotes odontogenic differentiation of human dental pulp cells by epigenetic regulation of DLX3.
HBeAg induces the expression of macrophage miR-155 to accelerate liver injury via promoting production of inflammatory cytokines.
Furin promotes dendritic morphogenesis and learning and memory in transgenic mice.
LGR5 promotes epithelial ovarian cancer proliferation, metastasis, and epithelial-mesenchymal transition through the Notch1 signaling pathway.
Farnesoid X receptor signaling activates the hepatic X-box binding protein 1 pathway in vitro and in mice.
Anti-fibrogenic Potential of Mesenchymal Stromal Cells in Treating Fibrosis in Crohn's Disease.
Glycyrrhizin ameliorates atopic dermatitis-like symptoms through inhibition of HMGB1.
LncRNA MT1DP Aggravates Cadmium-Induced Oxidative Stress by Repressing the Function of Nrf2 and is Dependent on Interaction with miR-365.
BCL11A Down-Regulation Induces γ-Globin in Human β-Thalassemia Major Erythroid Cells.
A proteomic approach reveals the differential protein expression in Drosophila melanogaster treated with red ginseng extract (Panax ginseng).
Fenretinide inhibits the proliferation and migration of human liver cancer HepG2 cells by downregulating the activation of myosin light chain kinase through the p38‑MAPK signaling pathway.
Programmed death ligand 1 promotes lymph node metastasis and glucose metabolism in cervical cancer by activating integrin β4/SNAI1/SIRT3 signaling pathway.
Estrogen-related receptor alpha is involved in Alzheimer's disease-like pathology.
The endosomal recycling of FgSnc1 by FgSnx41-FgSnx4 heterodimer is essential for polarized growth and pathogenicity in Fusarium graminearum.
Inhibition of Mitochondrial Fission Preserves Photoreceptors after Retinal Detachment.
Increased oxidative stress mediates the antitumor effect of PARP inhibition in ovarian cancer.
Sulforaphane attenuates microglia-mediated neuronal necroptosis through down-regulation of MAPK/NF-κB signaling pathways in LPS-activated BV-2 microglia.
Temporary inhibition of the plasminogen activator inhibits periosteal chondrogenesis and promotes periosteal osteogenesis during appendicular bone fracture healing.
BET bromodomain inhibitor JQ1 preferentially suppresses EBV-positive nasopharyngeal carcinoma cells partially through repressing c-Myc.
SET1A-Mediated Mono-Methylation at K342 Regulates YAP Activation by Blocking Its Nuclear Export and Promotes Tumorigenesis.
Naringenin exhibits the protective effect on cardiac hypertrophy via EETs-PPARs activation in streptozocin-induced diabetic mice.
The exon 19-deleted EGFR undergoes ubiquitylation-mediated endocytic degradation via dynamin activity-dependent and -independent mechanisms.
Ketamine differentially restores diverse alterations of neuroligins in brain regions in a rat model of neuropathic pain-induced depression.
Tristetraprolin Overexpression in Gastric Cancer Cells Suppresses PD-L1 Expression and Inhibits Tumor Progression by Enhancing Antitumor Immunity.
Circular RNA IARS (circ-IARS) secreted by pancreatic cancer cells and located within exosomes regulates endothelial monolayer permeability to promote tumor metastasis.
PEI-Coated Fe₃O₄ Nanoparticles Enable Efficient Delivery of Therapeutic siRNA Targeting REST into Glioblastoma Cells.
Imbalanced LIMK1 and LIMK2 expression leads to human colorectal cancer progression and metastasis via promoting β-catenin nuclear translocation.
17β-estradiol upregulates IL6 expression through the ERβ pathway to promote lung adenocarcinoma progression.
3-O-acetyl-11-keto-β-boswellic acid exerts anti-tumor effects in glioblastoma by arresting cell cycle at G2/M phase.
ZDHHC8 critically regulates seizure susceptibility in epilepsy.
FoxM1 repression during human aging leads to mitotic decline and aneuploidy-driven full senescence.
Long non-coding RNA PVT1 promotes malignancy in human endometrial carcinoma cells through negative regulation of miR-195-5p.
Comparison of the effects of selenomethionine and selenium-enriched yeast in the triple-transgenic mouse model of Alzheimer's disease.
Unique BIR domain sets determine inhibitor of apoptosis protein-driven cell death and NOD2 complex signal specificity.
Aspirin is Involved in the Cell Cycle Arrest, Apoptosis, Cell Migration, and Invasion of Oral Squamous Cell Carcinoma.
TNFRSF19 Inhibits TGFβ Signaling through Interaction with TGFβ Receptor Type I to Promote Tumorigenesis.
Protective effect of dioscin against thioacetamide-induced acute liver injury via FXR/AMPK signaling pathway in vivo.
Stachydrine ameliorates carbon tetrachloride-induced hepatic fibrosis by inhibiting inflammation, oxidative stress and regulating MMPs/TIMPs system in rats.
β-Arrestin-1 deficiency ameliorates renal interstitial fibrosis by blocking Wnt1/β-catenin signaling in mice.
Limb remote ischemia per-conditioning protects the heart against ischemia-reperfusion injury through the opioid system in rats.
Propofol attenuates myocardial ischemia reperfusion injury partly through inhibition of resident cardiac mast cell activation.
Vimentin is a crucial target for anti-metastasis therapy of nasopharyngeal carcinoma.
Knockdown of eukaryotic translation initiation factor 3 subunit D (eIF3D) inhibits proliferation of acute myeloid leukemia cells.
Proteasome inhibitor bortezomib is a novel therapeutic agent for focal radiation-induced osteoporosis.
Localization of endogenous amyloid-β to the coeruleo-cortical pathway: consequences of noradrenergic depletion.
Down-regulation of miR-10a-5p in synoviocytes contributes to TBX5-controlled joint inflammation.
Identification of two antiviral inhibitors targeting 3C-like serine/3C-like protease of porcine reproductive and respiratory syndrome virus and porcine epidemic diarrhea virus.
IgE induces hypotension in asthma mice by down-regulating vascular NCX1 expression through activating MiR-212-5p.
Cell Cycle-Dependent Tumor Engraftment and Migration Are Enabled by Aurora-A.
Sphingomyelin synthase 2 overexpression promotes cisplatin-induced apoptosis of HepG2 cells.
PTEN-L promotes type I interferon responses and antiviral immunity.
20-HETE regulated PSMB5 expression via TGF-β/Smad signaling pathway.
Icariin, a flavonoid with anti-cancer effects, alleviated paclitaxel-induced neuropathic pain in a SIRT1-dependent manner.
Downregulation of N(6)-methyladenosine binding YTHDF2 protein mediated by miR-493-3p suppresses prostate cancer by elevating N(6)-methyladenosine levels.
Inhibition of insulin resistance by PGE1 via autophagy-dependent FGF21 pathway in diabetic nephropathy.
Genomic and Epigenomic Profiling of High-Risk Intestinal Metaplasia Reveals Molecular Determinants of Progression to Gastric Cancer.
Neutrophil extracellular traps contribute to the pathogenesis of acid-aspiration-induced ALI/ARDS.
Protective Effects of Leukemia Inhibitory Factor on Retinal Vasculature and Cells in Streptozotocin-induced Diabetic Mice.
Antidiabetic activities of entagenic acid in type 2 diabetic db/db mice and L6 myotubes via AMPK/GLUT4 pathway.
LncRNA LOC730101 promotes osteosarcoma cell survival under energy stress.
Hydrogen-water ameliorates radiation-induced gastrointestinal toxicity via MyD88's effects on the gut microbiota.
Gentiopicroside ameliorates bleomycin-induced pulmonary fibrosis in mice via inhibiting inflammatory and fibrotic process.
C-MYC and BCL-2 mediate YAP-regulated tumorigenesis in OSCC.
Comprehensive Genomic Characterization of RNA-Binding Proteins across Human Cancers.
The Potential Roles of the Apoptosis-Related Protein PDRG1 in Diapause Embryo Restarting of Artemia sinica.
SOCE induced calcium overload regulates autophagy in acute pancreatitis via calcineurin activation.
IcarisideII improves left ventricular remodeling in spontaneously hypertensive rats by inhibiting the ASK1-JNK/p38 signaling pathway.
FBXO2, a novel marker for metastasis in human gastric cancer.
SIRT3 prevents angiotensin II-induced renal tubular epithelial-mesenchymal transition by ameliorating oxidative stress and mitochondrial dysfunction.
Exosomes derived from imatinib-resistant chronic myeloid leukemia cells mediate a horizontal transfer of drug-resistant trait by delivering miR-365.
Co-expression analysis revealed PTCH1-3'UTR promoted cell migration and invasion by activating miR-101-3p/SLC39A6 axis in non-small cell lung cancer: implicating the novel function of PTCH1.
Inhibition of autophagy-attenuated calcium oxalate crystal-induced renal tubular epithelial cell injury in vivo and in vitro.
MicroRNA-200a confers chemoresistance by antagonizing TP53INP1 and YAP1 in human breast cancer.
Pharmacological Investigation of the Anti-Inflammation and Anti-Oxidation Activities of Diallyl Disulfide in a Rat Emphysema Model Induced by Cigarette Smoke Extract.
GBP3 promotes glioma cell proliferation via SQSTM1/p62-ERK1/2 axis.
Protein Kinase A/CREB Signaling Prevents Adriamycin-Induced Podocyte Apoptosis via Upregulation of Mitochondrial Respiratory Chain Complexes.
MiR-208a-3p aggravates autophagy through the PDCD4-ATG5 pathway in Ang II-induced H9c2 cardiomyoblasts.
The E3 ubiquitin ligase MuRF2 attenuates LPS-induced macrophage activation by inhibiting production of inflammatory cytokines and migration.
Exosomes From Adipose-Derived Stem Cells Attenuate Adipose Inflammation and Obesity Through Polarizing M2 Macrophages and Beiging in White Adipose Tissue.
Speckle-Type POZ Protein Down-Regulates Matrix Metalloproteinase 2 Expression via Sp1/PI3K/Akt Signaling Pathway in Colorectal Cancer.
Proteasome-mediated degradation of collagen III by cortisol in amnion fibroblasts.
Telbivudine attenuates UUO-induced renal fibrosis via TGF-β/Smad and NF-κB signaling.
Clinical significance of C/D box small nucleolar RNA U76 as an oncogene and a prognostic biomarker in hepatocellular carcinoma.
Fungal β-Glucan Activates the NLRP3 Inflammasome in Human Bronchial Epithelial Cells Through ROS Production.
NLRC5 deficiency ameliorates diabetic nephropathy through alleviating inflammation.
Coordinated transcription of ANRIL and P16 genes is silenced by P16 DNA methylation.
Ephrin receptor A2 is an epithelial cell receptor for Epstein-Barr virus entry.
Intrinsic antimicrobial properties of silk spun by genetically modified silkworm strains.
Recurrent ECSIT mutation encoding V140A triggers hyperinflammation and promotes hemophagocytic syndrome in extranodal NK/T cell lymphoma.
The long non-coding RNA PVT1 represses ANGPTL4 transcription through binding with EZH2 in trophoblast cell.
Quantitative proteomics study of host response to virulent and attenuated pseudorabies virus infection in mouse brain.
SATB2 suppresses non-small cell lung cancer invasiveness by G9a.
Propofol protects against endotoxin-induced myocardial injury by inhibiting NF-κB-mediated inflammation.
Annexin A10 contributes to chronic constrictive injury-induced pain through activating ERK1/2 signalling in rats.
Decreased expression of hepatic cytochrome P450 1A2 (CYP1A2) in a chronic intermittent hypoxia mouse model.
Fasudil increases temozolomide sensitivity and suppresses temozolomide-resistant glioma growth via inhibiting ROCK2/ABCG2.
Photosensitization of A2E triggers telomere dysfunction and accelerates retinal pigment epithelium senescence.
Nicotine promotes atherosclerosis via ROS-NLRP3-mediated endothelial cell pyroptosis.
Flavagline analog FL3 induces cell cycle arrest in urothelial carcinoma cell of the bladder by inhibiting the Akt/PHB interaction to activate the GADD45α pathway.
Silencing Ras-Related C3 Botulinum Toxin Substrate 1 Inhibits Growth and Migration of Hypopharyngeal Squamous Cell Carcinoma via the P38 Mitogen-Activated Protein Kinase Signaling Pathway.
N-oleoylethanolamide suppresses intimal hyperplasia after balloon injury in rats through AMPK/PPARα pathway.
Estrogen directly stimulates LHb expression at the pituitary level during puberty in female zebrafish.
l-Menthol alleviates cigarette smoke extract induced lung injury in rats by inhibiting oxidative stress and inflammation via nuclear factor kappa B, p38 MAPK and Nrf2 signalling pathways.
Ginsenoside Rg3 sensitizes hypoxic lung cancer cells to cisplatin via blocking of NF-κB mediated epithelial-mesenchymal transition and stemness.
Comprehensive integrative analyses identify GLT8D1 and CSNK2B as schizophrenia risk genes.
Liver-specific deletion of TSHR inhibits hepatic lipid accumulation in mice.
PIM1 mediates epithelial-mesenchymal transition by targeting Smads and c-Myc in the nucleus and potentiates clear-cell renal-cell carcinoma oncogenesis.
High-fat Diet Mediates Anxiolytic-like Behaviors in a Time-dependent Manner Through the Regulation of SIRT1 in the Brain.
GRK5 functions as an oncogenic factor in non-small-cell lung cancer.
TRAF6 regulates EGF-induced cell transformation and cSCC malignant phenotype through CD147/EGFR.
Interferon-alpha enhances the antitumour activity of EGFR-targeted therapies by upregulating RIG-I in head and neck squamous cell carcinoma.
Upregulation of kinesin family member 4A enhanced cell proliferation via activation of Akt signaling and predicted a poor prognosis in hepatocellular carcinoma.
NIT1 suppresses tumour proliferation by activating the TGFβ1-Smad2/3 signalling pathway in colorectal cancer.
Molecular adaptations of adipose tissue to 6 weeks of morning fasting vs. daily breakfast consumption in lean and obese adults.
Hypoxia Activates Src and Promotes Endocytosis Which Decreases MMP-2 Activity and Aggravates Renal Interstitial Fibrosis.
hPMSC transplantation restoring ovarian function in premature ovarian failure mice is associated with change of Th17/Tc17 and Th17/Treg cell ratios through the PI3K/Akt signal pathway.
Polycystin-2 is an essential ion channel subunit in the primary cilium of the renal collecting duct epithelium.
MYL6B, a myosin light chain, promotes MDM2-mediated p53 degradation and drives HCC development.
MicroRNA-29a mitigation of toll-like receptor 2 and 4 signaling and alleviation of obstructive jaundice-induced fibrosis in mice.
Ursolic Acid Attenuates High Glucose-Mediated Mesangial Cell Injury by Inhibiting the Phosphatidylinositol 3-Kinase/Akt/Mammalian Target of Rapamycin (PI3K/Akt/mTOR) Signaling Pathway.
Fertility impairment with defective spermatogenesis and steroidogenesis in male zebrafish lacking androgen receptor.
Overcoming STC2 mediated drug resistance through drug and gene co-delivery by PHB-PDMAEMA cationic polyester in liver cancer cells.
AF119895 regulates NXF3 expression to promote migration and invasion of hepatocellular carcinoma through an interaction with miR-6508-3p.
Bone marrow mesenchymal stromal cells alleviate brain white matter injury via the enhanced proliferation of oligodendrocyte progenitor cells in focal cerebral ischemic rats.
Truncated SALL1 Impedes Primary Cilia Function in Townes-Brocks Syndrome.
Novel synthetic 4-chlorobenzoyl berbamine inhibits c-Myc expression and induces apoptosis of diffuse large B cell lymphoma cells.
Quercetin ameliorates pulmonary fibrosis by inhibiting SphK1/S1P signaling.
Red nucleus interleukin-1β evokes tactile allodynia through activation of JAK/STAT3 and JNK signaling pathways.
Apolipoprotein E Exerts a Whole-Brain Protective Property by Promoting M1? Microglia Quiescence After Experimental Subarachnoid Hemorrhage in Mice.
IL-23-induced macrophage polarization and its pathological roles in mice with imiquimod-induced psoriasis.
Autophagy participates in innate immune defense in lamprey.
Establishing a dual knock-out cell line by lentivirus based combined CRISPR/Cas9 and Loxp/Cre system.
Buffalo oocyte-secreted factors promote cumulus cells apoptosis and the rate of cGMP production but not steroidogenesis.
Prolyl hydroxylases positively regulated LPS-induced inflammation in human gingival fibroblasts via TLR4/MyD88-mediated AKT/NF-κB and MAPK pathways.
Overexpression of CXCL2 inhibits cell proliferation and promotes apoptosis in hepatocellular carcinoma.
PI3K/Akt signaling pathway and Hsp70 activate in hippocampus of rats with chronic manganese sulfate exposure.
Klotho gene-modified BMSCs showed elevated antifibrotic effects by inhibiting the Wnt/β-catenin pathway in kidneys after acute injury.
miR‑29a suppresses the growth and metastasis of hepatocellular carcinoma through IFITM3.
The Scorpion Venom Peptide Smp76 Inhibits Viral Infection by Regulating Type-I Interferon Response.
Elevating ATP-binding cassette transporter G1 improves re-endothelialization function of endothelial progenitor cells via Lyn/Akt/eNOS in diabetic mice.
Phenethyl isothiocyanate inhibits colorectal cancer stem cells by suppressing Wnt/β-catenin pathway.
MicroRNA-146b-3p Promotes Cell Metastasis by Directly Targeting NF2 in Human Papillary Thyroid Cancer.
Expression Analysis of ACSL5 and Wnt2B in Human Congenital Pulmonary Airway Malformations.
Effects of mdig on proliferation and apoptosis of lung cancer cells.
Influencing mechanism of magnolol on expression of BDNF and Bax in rats with cerebral ischemic stroke.
Regulation of hippocampal long term depression by Neuroligin 1.
Cathelicidin-WA attenuates LPS-induced inflammation and redox imbalance through activation of AMPK signaling.
Mechanism and prognostic value of indoleamine 2,3-dioxygenase 1 expressed in hepatocellular carcinoma.
Transcription factor 7-like 2 controls matrix degradation through nuclear factor κB signaling and is repressed by microRNA-155 in nucleus pulposus cells.
PNMA1, regulated by miR-33a-5p, promotes proliferation and EMT in hepatocellular carcinoma by activating the Wnt/β-catenin pathway.
Dynasore-induced potent ubiquitylation of the exon 19 deletion mutant of epidermal growth factor receptor suppresses cell growth and migration in non-small cell lung cancer.
A novel pathway of LPS uptake through syndecan-1 leading to pyroptotic cell death.
A Simplified System to Express Circularized Inhibitors of miRNA for Stable and Potent Suppression of miRNA Functions.
NR2C2-uORF targeting UCA1-miR-627-5p-NR2C2 feedback loop to regulate the malignant behaviors of glioma cells.
MAN1B1 is associated with poor prognosis and modulates proliferation and apoptosis in bladder cancer.
LINC00052/miR-101-3p axis inhibits cell proliferation and metastasis by targeting SOX9 in hepatocellular carcinoma.
Systematic analysis of synergistic proteome modulations in a drug combination of cisplatin and MLN4924.
4'-hydroxywogonin inhibits colorectal cancer angiogenesis by disrupting PI3K/AKT signaling.
Anti-tumoral potential of MDA19 in human osteosarcoma via suppressing PI3K/Akt/mTOR signaling pathway.
Jian-Pi-Yi-Shen Formula ameliorates chronic kidney disease: involvement of mitochondrial quality control network.
Gli2 modulates cell cycle re-entry through autophagy-mediated regulation of the length of primary cilia.
CVB3 Nonstructural 2A Protein Modulates SREBP1a Signaling via the MEK/ERK Pathway.
Perigestational exposure to low doses of PBDE-47 induces excessive ER stress, defective autophagy and the resultant apoptosis contributing to maternal thyroid toxicity.
Dexmedetomidine alleviates cerebral ischemia-reperfusion injury by inhibiting endoplasmic reticulum stress dependent apoptosis through the PERK-CHOP-Caspase-11 pathway.
Metformin regulates atrial SK2 and SK3 expression through inhibiting the PKC/ERK signaling pathway in type 2 diabetic rats.
Epigenetic suppression of E-cadherin expression by Snail2 during the metastasis of colorectal cancer.
Co-targeting PLK1 and mTOR induces synergistic inhibitory effects against esophageal squamous cell carcinoma.
miR-128-3p regulates 3T3-L1 adipogenesis and lipolysis by targeting Pparg and Sertad2.
Radiosensitizing effects of miR-18a-5p on lung cancer stem-like cells via downregulating both ATM and HIF-1α.
NRG1 regulates redox homeostasis via NRF2 in papillary thyroid cancer.
Overexpression of PRDM13 inhibits glioma cells via Rho and GTP enzyme activation protein.
Overexpression of FOXQ1 enhances anti-senescence and migration effects of human umbilical cord mesenchymal stem cells in vitro and in vivo.
Scribble influences cyst formation in autosomal-dominant polycystic kidney disease by regulating Hippo signaling pathway.
Increased Expression of NDRG3 in Mouse Uterus During Embryo Implantation and in Mouse Endometrial Stromal Cells During In Vitro Decidualization.
LncRNA BDNF-AS inhibits proliferation, migration, invasion and EMT in oesophageal cancer cells by targeting miR-214.
Revealing A-Raf functions through its interactome.
miR-205-5p inhibits cell migration and invasion in prostatic carcinoma by targeting ZEB1.
Peri-ovarian adipose tissue contributes to intraovarian control during folliculogenesis in mice.
MicroRNA-135a inhibits cardiac fibrosis induced by isoproterenol via TRPM7 channel.
ITGBL1 promotes migration, invasion and predicts a poor prognosis in colorectal cancer.
Warfarin and vitamin K epoxide reductase: a molecular accounting for observed inhibition.
Anillin is required for tumor growth and regulated by miR-15a/miR-16-1 in HBV-related hepatocellular carcinoma.
HMGB1 knockdown increases MM cell vulnerability by regulating autophagy and DNA damage repair.
Ubiquitin-conjugating enzyme UBE2J1 negatively modulates interferon pathway and promotes RNA virus infection.
MALAT1-miR663a negative feedback loop in colon cancer cell functions through direct miRNA-lncRNA binding.
Hepatocyte Wnts Are Dispensable During Diethylnitrosamine and Carbon Tetrachloride-Induced Injury and Hepatocellular Cancer.
Cold atmospheric plasma conveys selectivity on triple negative breast cancer cells both in vitro and in vivo.
Increased Expression of CD81 in Breast Cancer Tissue is Associated with Reduced Patient Prognosis and Increased Cell Migration and Proliferation in MDA-MB-231 and MDA-MB-435S Human Breast Cancer Cell Lines In Vitro.
Motoneuron Wnts regulate neuromuscular junction development.
Inhibition of mTORC1 signaling protects kidney from irradiation-induced toxicity via accelerating recovery of renal stem-like cells.
Transactive Response DNA-Binding Protein 43 Abnormalities after Traumatic Brain Injury.
Antifertility effectiveness of a novel copper-containing intrauterine device material and its influence on the endometrial environment in rats.
Lanthanum chloride reduces lactate production in primary culture rat cortical astrocytes and suppresses primary co-culture rat cortical astrocyte-neuron lactate transport.
Interleukin-17A participates in podocyte injury by inducing IL-1β secretion through ROS-NLRP3 inflammasome-caspase-1 pathway.
PARP inhibitor olaparib sensitizes cholangiocarcinoma cells to radiation.
Gemin5 plays a role in unassembled-U1 snRNA disposal in SMN-deficient cells.
MDM2 Degrades Deacetylated Nucleolin Through Ubiquitination to Promote Glioma Stem-Like Cell Enrichment for Chemotherapeutic Resistance.
Rolipram Attenuates Early Brain Injury Following Experimental Subarachnoid Hemorrhage in Rats: Possibly via Regulating the SIRT1/NF-κB Pathway.
miR‑21‑5p confers doxorubicin resistance in gastric cancer cells by targeting PTEN and TIMP3.
MiR-151a is involved in the pathogenesis of atopic dermatitis by regulating interleukin-12 receptor β2.
Targeting P-glycoprotein and SORCIN: Dihydromyricetin strengthens anti-proliferative efficiency of adriamycin via MAPK/ERK and Ca(2+) -mediated apoptosis pathways in MCF-7/ADR and K562/ADR.
TXNDC5 contributes to rheumatoid arthritis by down-regulating IGFBP1 expression.
Phenformin inhibits cell proliferation and induces cell apoptosis and autophagy in cholangiocarcinoma.
Zoledronic acid sensitizes breast cancer cells to fulvestrant via ERK/HIF-1 pathway inhibition in vivo.
Effect of TLR4/MyD88 signaling pathway on sepsis-associated acute respiratory distress syndrome in rats, via regulation of macrophage activation and inflammatory response.
Screening the expression characteristics of several miRNAs in G93A-SOD1 transgenic mouse: altered expression of miRNA-124 is associated with astrocyte differentiation by targeting Sox2 and Sox9.
TSR2 Induces laryngeal cancer cell apoptosis through inhibiting NF-κB signaling pathway.
Icariside II attenuates myocardial fibrosis by inhibiting nuclear factor-κB and the TGF-β1/Smad2 signalling pathway in spontaneously hypertensive rats.
Apocynum venetum leaf extract reverses depressive-like behaviors in chronically stressed rats by inhibiting oxidative stress and apoptosis.
Ezrin/NF-κB Pathway Regulates EGF-induced Epithelial-Mesenchymal Transition (EMT), Metastasis, and Progression of Osteosarcoma.
Protective effect of methylallyl sulfone in the development of cigarette smoke extract-induced apoptosis in rats and HFL-1 cells.
R-spondin3-LGR4 signaling protects hepatocytes against DMOG-induced hypoxia/reoxygenation injury through activating β-catenin.
Down-regulation of miR-10a-5p promotes proliferation and restricts apoptosis via targeting T-box transcription factor 5 in inflamed synoviocytes.
Characterization of RUNX1T1, an Adipogenesis Regulator in Ovine Preadipocyte Differentiation.
Ehrlichia chaffeensis TRP75 Interacts with Host Cell Targets Involved in Homeostasis, Cytoskeleton Organization, and Apoptosis Regulation To Promote Infection.
The LINC01138 drives malignancies via activating arginine methyltransferase 5 in hepatocellular carcinoma.
RUVBL1, a novel C-RAF-binding protein, activates the RAF/MEK/ERK pathway to promote lung cancer tumorigenesis.
RGC32 Promotes Bleomycin-Induced Systemic Sclerosis in a Murine Disease Model by Modulating Classically Activated Macrophage Function.
Vitamin A pretreatment protects NO-induced bovine mammary epithelial cells from oxidative stress by modulating Nrf2 and NF-κB signaling pathways.
gga-miR-451 Negatively Regulates Mycoplasma gallisepticum (HS Strain)-Induced Inflammatory Cytokine Production via Targeting YWHAZ.
Lysophosphatidic Acid Induces ECM Production via Activation of the Mechanosensitive YAP/TAZ Transcriptional Pathway in Trabecular Meshwork Cells.
Caspase Inhibition Reduces Hepatic Tissue Factor-Driven Coagulation In Vitro and In Vivo.
IncRNA H19 promotes tongue squamous cell carcinoma progression through β-catenin/GSK3β/EMT signaling via association with EZH2.
RIZ1 negatively regulates ubiquitin-conjugating enzyme E2C/UbcH10 via targeting c-Myc in meningioma.
Down-regulation of miR-125a-5p is associated with salivary adenoid cystic carcinoma progression via targeting p38/JNK/ERK signal pathway.
Upregulation of TSPAN12 is associated with the colorectal cancer growth and metastasis.
DDX3 binding with CK1ε was closely related to motor neuron degeneration of ALS by affecting neurite outgrowth.
Levodopa/Benserazide Loaded Microspheres Alleviate L-dopa Induced Dyskinesia through Preventing the Over-Expression of D1R/Shp-2/ERK1/2 Signaling Pathway in a Rat Model of Parkinson's Disease.
The role of the chemokine receptor XCR1 in breast cancer cells.
The Frequency-Dependent Aerobic Exercise Effects of Hypothalamic GABAergic Expression and Cardiovascular Functions in Aged Rats.
Methylation of ZNF331 is an independent prognostic marker of colorectal cancer and promotes colorectal cancer growth.
Downregulation of Mitochondrial Single Stranded DNA Binding Protein (SSBP1) Induces Mitochondrial Dysfunction and Increases the Radiosensitivity in Non-Small Cell Lung Cancer Cells.
HES1 Promotes Colorectal Cancer Cell Resistance To 5-Fu by Inducing Of EMT and ABC Transporter Proteins.
CDC27 Induces Metastasis and Invasion in Colorectal Cancer via the Promotion of Epithelial-To-Mesenchymal Transition.
Interferon-α Promotes the Expression of Cancer Stem Cell Markers in Oral Squamous Cell Carcinoma.
In vitro Cytotoxic Activities of the Oral Platinum(IV) Prodrug Oxoplatin and HSP90 Inhibitor Ganetespib against a Panel of Gastric Cancer Cell Lines.
Carnosic Acid Alleviates BDL-Induced Liver Fibrosis through miR-29b-3p-Mediated Inhibition of the High-Mobility Group Box 1/Toll-Like Receptor 4 Signaling Pathway in Rats.
Antidiabetic Effect of Tibetan Medicine Tang-Kang-Fu-San in db/db Mice via Activation of PI3K/Akt and AMPK Pathways.
Fentanyl Promotes Breast Cancer Cell Stemness and Epithelial-Mesenchymal Transition by Upregulating α1, 6-Fucosylation via Wnt/β-Catenin Signaling Pathway.
Lactobacillus rhamnosus GG Affects Microbiota and Suppresses Autophagy in the Intestines of Pigs Challenged with Salmonella Infantis.
Screening and Identification of the Host Proteins Interacting with Toxoplasma gondii Rhoptry Protein ROP16.
Lab-Attenuated Rabies Virus Causes Abortive Infection and Induces Cytokine Expression in Astrocytes by Activating Mitochondrial Antiviral-Signaling Protein Signaling Pathway.
Protective Effects of Dioscin against Lipopolysaccharide-Induced Acute Lung Injury through Inhibition of Oxidative Stress and Inflammation.
LncRNA ZFAS1 promotes growth and metastasis by regulating BMI1 and ZEB2 in osteosarcoma.
Obatoclax and LY3009120 Efficiently Overcome Vemurafenib Resistance in Differentiated Thyroid Cancer.
miR-381-3p suppresses the proliferation of oral squamous cell carcinoma cells by directly targeting FGFR2.
NRSN2 promotes osteosarcoma cell proliferation and growth through PI3K/Akt/MTOR and Wnt/β-catenin signaling.
Angiopoietin-like protein 2 facilitates non-small cell lung cancer progression by promoting the polarization of M2 tumor-associated macrophages.
Targeting NF-κB/AP-2β signaling to enhance antitumor activity of cisplatin by melatonin in hepatocellular carcinoma cells.
Exogenous H(2)S restores ischemic post-conditioning-induced cardioprotection through inhibiting endoplasmic reticulum stress in the aged cardiomyocytes.
Oral Administration of Lactobacillus rhamnosus GG Ameliorates Salmonella Infantis-Induced Inflammation in a Pig Model via Activation of the IL-22BP/IL-22/STAT3 Pathway.
In-Cell Western Assays to Evaluate Hantaan Virus Replication as a Novel Approach to Screen Antiviral Molecules and Detect Neutralizing Antibody Titers.
Selenomethionine Attenuates the Amyloid-β Level by Both Inhibiting Amyloid-β Production and Modulating Autophagy in Neuron-2a/AβPPswe Cells.
MiR-142-5p Suppresses Tumorigenesis by Targeting PIK3CA in Non-Small Cell Lung Cancer.
Iridoids with Genipin Stem Nucleus Inhibit Lipopolysaccharide-Induced Inflammation and Oxidative Stress by Blocking the NF-κB Pathway in Polycystic Ovary Syndrome.
The USP7 Inhibitor P5091 Induces Cell Death in Ovarian Cancers with Different P53 Status.
Involvement of S100A8/A9-TLR4-NLRP3 Inflammasome Pathway in Contrast-Induced Acute Kidney Injury.
The Lncrna-TUG1/EZH2 Axis Promotes Pancreatic Cancer Cell Proliferation, Migration and EMT Phenotype Formation Through Sponging Mir-382.
Deoxyelephantopin Induces Reactive Oxygen Species-Mediated Apoptosis and Autophagy in Human Osteosarcoma Cells.
CDC5L Promotes hTERT Expression and Colorectal Tumor Growth.
SOX6 Downregulation Induces γ-Globin in Human β-Thalassemia Major Erythroid Cells.
Neutrophil Extracellular Traps Are Pathogenic in Ventilator-Induced Lung Injury and Partially Dependent on TLR4.
Resveratrol Prevents ROS-Induced Apoptosis in High Glucose-Treated Retinal Capillary Endothelial Cells via the Activation of AMPK/Sirt1/PGC-1α Pathway.
Differentiation of Human Amniotic Mesenchymal Stem Cells into Human Anterior Cruciate Ligament Fibroblast Cells by In Vitro Coculture.
Antidiabetic Effect of Tibetan Medicine Tang-Kang-Fu-San on High-Fat Diet and Streptozotocin-Induced Type 2 Diabetic Rats.
Salusin-β Is Involved in Diabetes Mellitus-Induced Endothelial Dysfunction via Degradation of Peroxisome Proliferator-Activated Receptor Gamma.
Electroacupuncture Alleviates Postoperative Cognitive Dysfunction in Aged Rats by Inhibiting Hippocampal Neuroinflammation Activated via Microglia/TLRs Pathway.
HIV-1 Transactivator Protein Induces ZO-1 and Neprilysin Dysfunction in Brain Endothelial Cells via the Ras Signaling Pathway.
Long-Term Effects of TCM Yangqing Kangxian Formula on Bleomycin-Induced Pulmonary Fibrosis in Rats via Regulating Nuclear Factor-κB Signaling.
Synthetic Isoliquiritigenin Inhibits Human Tongue Squamous Carcinoma Cells through Its Antioxidant Mechanism.
ROR2 receptor promotes the migration of osteosarcoma cells in response to Wnt5a.
HSPB8 Promotes the Fusion of Autophagosome and Lysosome during Autophagy in Diabetic Neurons.
LncRNA AFAP1-AS Functions as a Competing Endogenous RNA to Regulate RAP1B Expression by sponging miR-181a in the HSCR.
Exosomes Derived from Human Pulmonary Artery Endothelial Cells Shift the Balance between Proliferation and Apoptosis of Smooth Muscle Cells.
Resveratrol ameliorates diet-induced dysregulation of lipid metabolism in zebrafish (Danio rerio).
Caveolin1 protects against diet induced hepatic lipid accumulation in mice.
Imatinib attenuates cardiac fibrosis by inhibiting platelet-derived growth factor receptors activation in isoproterenol induced model.
A mutation in the CACNA1C gene leads to early repolarization syndrome with incomplete penetrance: A Chinese family study.
Role of keratin 24 in human epidermal keratinocytes.
Far-infrared suppresses skin photoaging in ultraviolet B-exposed fibroblasts and hairless mice.
Increased expression of protein kinase CK2α correlates with poor patient prognosis in epithelial ovarian cancer.
Aerobic exercise regulates Rho/cofilin pathways to rescue synaptic loss in aged rats.
Rottlerin as a therapeutic approach in psoriasis: Evidence from in vitro and in vivo studies.
Down-regulation of the klf5-c-Myc interaction due to klf5 phosphorylation mediates resveratrol repressing the caveolin-1 transcription through the PI3K/PKD1/Akt pathway.
XRCC5 cooperates with p300 to promote cyclooxygenase-2 expression and tumor growth in colon cancers.
MITA/STING and Its Alternative Splicing Isoform MRP Restrict Hepatitis B Virus Replication.
Gold nanoparticles attenuate metastasis by tumor vasculature normalization and epithelial-mesenchymal transition inhibition.
Knockdown of Long Non-Coding RNA KCNQ1OT1 Restrained Glioma Cells' Malignancy by Activating miR-370/CCNE2 Axis.
Involvement of endoplasmic reticulum stress in formalin-induced pain is attenuated by 4-phenylbutyric acid.
UNBS5162 inhibits proliferation of human retinoblastoma cells by promoting cell apoptosis.
The Effect of MCM3AP-AS1/miR-211/KLF5/AGGF1 Axis Regulating Glioblastoma Angiogenesis.
Circ-104916 is downregulated in gastric cancer and suppresses migration and invasion of gastric cancer cells.
PIK3CA expression in diffuse large B cell lymphoma tissue and the effect of its knockdown in vitro.
The Role of HOTAIR/miR-148b-3p/USF1 on Regulating the Permeability of BTB.
Downregulation of the Repressor Element 1-Silencing Transcription Factor (REST) Is Associated with Akt-mTOR and Wnt-β-Catenin Signaling in Prion Diseases Models.
Tail vein injection of mmLDL upregulates mouse mesenteric artery ET(B) receptors via activation of the ERK1/2 pathway.
Calreticulin regulates TGF-β1-induced epithelial mesenchymal transition through modulating Smad signaling and calcium signaling.
Ehrlichia chaffeensis TRP120 Moonlights as a HECT E3 Ligase Involved in Self- and Host Ubiquitination To Influence Protein Interactions and Stability for Intracellular Survival.
Ligustrazine modulates renal cysteine biosynthesis in rats exposed to cadmium.
The transcription factor cyclic adenosine 3',5'-monophosphate response element-binding protein enhances the odonto/osteogenic differentiation of stem cells from the apical papilla.
lncRNA-PVT1 Facilitates Invasion Through Upregulation of MMP9 in Nonsmall Cell Lung Cancer Cell.
Stool DNA Test of Methylated Syndecan-2 for the Early Detection of Colorectal Neoplasia.
Vertebrate Lonesome Kinase Regulated Extracellular Matrix Protein Phosphorylation, Cell Shape, and Adhesion in Trabecular Meshwork Cells.
An oligodeoxynucleotide with AAAG repeats significantly attenuates burn-induced systemic inflammatory responses via inhibiting interferon regulatory factor 5 pathway.
TNF-α promotes survival and migration of MSCs under oxidative stress via NF-κB pathway to attenuate intimal hyperplasia in vein grafts.
Assessment of tris (1, 3-dichloro-2-propyl) phosphate toxicology in PC12 cells by using digital gene expression profiling.
Attenuation of doxorubicin-induced cardiotoxicity by esculetin through modulation of Bmi-1 expression.
Dioscin, a potent ITGA5 inhibitor, reduces the synthesis of collagen against liver fibrosis: Insights from SILAC-based proteomics analysis.
Predictive single nucleotide polymorphism markers for acute oral mucositis in patients with nasopharyngeal carcinoma treated with radiotherapy.
Hsp90 activator Aha1 drives production of pathological tau aggregates.
Sirt6 deficiency exacerbates podocyte injury and proteinuria through targeting Notch signaling.
FAM83D, a microtubule-associated protein, promotes tumor growth and progression of human gastric cancer.
Numb positively regulates autophagic flux via regulating lysosomal function.
Overexpression of miR-135b-5p promotes unfavorable clinical characteristics and poor prognosis via the repression of SFRP4 in pancreatic cancer.
Regulation of the epithelial Na(+) channel by paraoxonase-2.
Long non-coding RNA NEAT1 regulates epithelial membrane protein 2 expression to repress nasopharyngeal carcinoma migration and irradiation-resistance through miR-101-3p as a competing endogenous RNA mechanism.
Heat-killed salmonella typhimurium (HKST) protects mice against radiation in TLR4-dependent manner.
Testosterone regulates 3T3-L1 pre-adipocyte differentiation and epididymal fat accumulation in mice through modulating macrophage polarization.
Cloning, expression pattern, and potential role of apoptosis inhibitor 5 in the termination of embryonic diapause and early embryo development of Artemia sinica.
Ezrin as a possible diagnostic and/or prognostic biomarker in mice lymphatic metastatic hepatocellular carcinoma in vivo.
Phorbol esters dPPA/dPA promote furin expression involving transcription factor CEBPβ in neuronal cells.
Live-cell visualization of gasdermin D-driven pyroptotic cell death.
ORMDL3 Facilitates the Survival of Splenic B Cells via an ATF6α-Endoplasmic Reticulum Stress-Beclin1 Autophagy Regulatory Pathway.
New Insights Into the Role of Estrogens in Male Fertility Based on Findings in Aromatase-Deficient Zebrafish.
Lithium alleviates neurotoxic prion peptide-induced synaptic damage and neuronal death partially by the upregulation of nuclear target REST and the restoration of Wnt signaling.
Role of Pannexin1 channels in the resistance of I-10 testicular cancer cells to cisplatin mediated by ATP/IP(3) pathway.
Cadmium chloride-induced testicular toxicity in male wistar rats; prophylactic effect of quercetin, and assessment of testicular recovery following cadmium chloride withdrawal.
In vitro anticancer activities of osthole against renal cell carcinoma cells.
Metformin Inhibits Porphyromonas gingivalis Lipopolysaccharide-Influenced Inflammatory Response in Human Gingival Fibroblasts via Regulating Activating Transcription Factor-3 Expression.
A potential contribution of dipeptidyl peptidase-4 by the mediation of monocyte differentiation in the development and progression of abdominal aortic aneurysms.
CISD2 enhances the chemosensitivity of gastric cancer through the enhancement of 5-FU-induced apoptosis and the inhibition of autophagy by AKT/mTOR pathway.
Propofol inhibits invasion and proliferation of C6 glioma cells by regulating the Ca(2+) permeable AMPA receptor-system x(c)(-) pathway.
Trichostatin A attenuates oxidative stress-mediated myocardial injury through the FoxO3a signaling pathway.
Zinc finger protein 307 functions as a tumor‑suppressor and inhibits cell proliferation by inducing apoptosis in hepatocellular carcinoma.
Varicella-zoster virus ORF7 interacts with ORF53 and plays a role in its trans-Golgi network localization.
The effects of fluoride on neuronal function occurs via cytoskeleton damage and decreased signal transmission.
Proteasomal degradation of T. gondii ROP18 requires Derlin2.
Dietary Selenium Deficiency or Excess Reduces Sperm Quality and Testicular mRNA Abundance of Nuclear Glutathione Peroxidase 4 in Rats.
ERβ compensates for the absence of ERα function to promote osteoblast viability by inhibition of SOST signaling.
Caveolin 1-related autophagy initiated by aldosterone-induced oxidation promotes liver sinusoidal endothelial cells defenestration.
Neuroprotective Effects of Loganin on MPTP-Induced Parkinson's Disease Mice: Neurochemistry, Glial Reaction and Autophagy Studies.
Ligustilide Relieves Complete Freund's Adjuvant-induced Mechanical Hyperalgesia through Inhibiting the Activation of Spinal c-Jun N-terminal Kinase/c-Jun Pathway in Rats.
RTN1-C mediates cerebral ischemia/reperfusion injury via ER stress and mitochondria-associated apoptosis pathways.
High expression of IL-4R enhances proliferation and invasion of hepatocellular carcinoma cells.
Circular RNA HIPK2 regulates astrocyte activation via cooperation of autophagy and ER stress by targeting MIR124-2HG.
Calreticulin promotes EGF-induced EMT in pancreatic cancer cells via Integrin/EGFR-ERK/MAPK signaling pathway.
ANP promotes proliferation and inhibits apoptosis of ovarian granulosa cells by NPRA/PGRMC1/EGFR complex and improves ovary functions of PCOS rats.
Protective Effect of Flavonoids from Ziziphus jujuba cv. Jinsixiaozao against Acetaminophen-Induced Liver Injury by Inhibiting Oxidative Stress and Inflammation in Mice.
Centriolin, a centriole-appendage protein, regulates peripheral spindle migration and asymmetric division in mouse meiotic oocytes.
MicroRNA-20a-mediated loss of autophagy contributes to breast tumorigenesis by promoting genomic damage and instability.
Linc-RoR promotes MAPK/ERK signaling and confers estrogen-independent growth of breast cancer.
MicroRNA-21 suppresses ox-LDL-induced human aortic endothelial cells injuries in atherosclerosis through enhancement of autophagic flux: Involvement in promotion of lysosomal function.
Rab11a is required for porcine reproductive and respiratory syndrome virus induced autophagy to promote viral replication.
Aneuploid Cell Survival Relies upon Sphingolipid Homeostasis.
Far infrared promotes wound healing through activation of Notch1 signaling.
Role of NF-κB/GATA3 in the inhibition of lysyl oxidase by IL-1β in human amnion fibroblasts.
Long non-coding RNA HOTTIP promotes hypoxia-induced epithelial-mesenchymal transition of malignant glioma by regulating the miR-101/ZEB1 axis.
Berberine activates caspase-9/cytochrome c-mediated apoptosis to suppress triple-negative breast cancer cells in vitro and in vivo.
Spiroplasma eriocheiris induces mouse 3T6-Swiss albino cell apoptosis that associated with the infection mechanism.
Effects of melatonin on the proliferation and differentiation of human dental pulp cells.
MYC protein dysregulation is driven by BCR-PI3K signalling in diffuse large B-cell lymphoma.
Effectively enhancing cytotoxic and apoptotic effects of alpha-momorcharin by integrating a heparin-binding peptide.
Artesunate induces apoptosis via inhibition of STAT3 in THP-1 cells.
MAPK/p38 regulation of cytoskeleton rearrangement accelerates induction of macrophage activation by TLR4, but not TLR3.
Platelet rich plasma promotes skeletal muscle cell migration in association with up-regulation of FAK, paxillin, and F-Actin formation.
Endothelial cell SHP-2 negatively regulates neutrophil adhesion and promotes transmigration by enhancing ICAM-1-VE-cadherin interaction.
Sodium selenate activated Wnt/β-catenin signaling and repressed amyloid-β formation in a triple transgenic mouse model of Alzheimer's disease.
Neuroprotection of hypoxic postconditioning against global cerebral ischemia through influencing posttranslational regulations of heat shock protein 27 in adult rats.
Rho-kinase inhibitor Y-27632 facilitates the proliferation, migration and pluripotency of human periodontal ligament stem cells.
Focal adhesion kinase family is involved in matrix contraction by transdifferentiated Müller cells.
IFNA2 p.Ala120Thr impairs the inhibitory activity of Interferon-α2 against the hepatitis B virus through altering its binding to the receptor.
Reactive oxygen species-responsive polymeric nanoparticles for alleviating sepsis-induced acute liver injury in mice.
Downregulated long non-coding RNA TCONS_00068220 upregulates apoptosis in gastric cancer cells.
p63 inhibits CD44(+)/CD24(-) cell proliferation and chemoresistance in papillary thyroid carcinoma cells.
Generation of apoptosis-resistant HEK293 cells with CRISPR/Cas mediated quadruple gene knockout for improved protein and virus production.
β-d-glucan from Antrodia Camphorata ameliorates LPS-induced inflammation and ROS production in human hepatocytes.
Cell contact and pressure control of YAP localization and clustering revealed by super-resolution imaging.
Insulin-like growth factor 2 mRNA binding protein 3 (IGF2BP3) promotes lung tumorigenesis via attenuating p53 stability.
Targeted Metabolomics Reveals Abnormal Hepatic Energy Metabolism by Depletion of β-Carotene Oxygenase 2 in Mice.
DC2 and KCP2 mediate the interaction between the oligosaccharyltransferase and the ER translocon.
Curcumin inhibits bladder cancer stem cells by suppressing Sonic Hedgehog pathway.
Upregulation of SOX2 activated LncRNA PVT1 expression promotes breast cancer cell growth and invasion.
Cholecalciterol cholesterol emulsion attenuates experimental autoimmune myocarditis in mice via inhibition of the pyroptosis signaling pathway.
Autocrine Interleukin-10 Mediates Glucagon-Like Peptide-1 Receptor-Induced Spinal Microglial β-Endorphin Expression.
Metformin reverses bFGF-induced epithelial-mesenchymal transition in HCC cells.
MiR-16-5p mediates a positive feedback loop in EV71-induced apoptosis and suppresses virus replication.
Proteomics and metabolomics analysis of hepatic mitochondrial metabolism in alcohol-preferring and non-preferring rats.
Pim-3 as a potential predictor of chemoradiotherapy resistance in locally advanced rectal cancer patients.
AKAP95-mediated nuclear anchoring of PKA mediates cortisol-induced PTGS2 expression in human amnion fibroblasts.
Levels of Leydig cell autophagy regulate the fertility of male naked mole-rats.
High expression of PDLIM5 facilitates cell tumorigenesis and migration by maintaining AMPK activation in prostate cancer.
Different miR-21-3p isoforms and their different features in colorectal cancer.
DLX3 promotes bone marrow mesenchymal stem cell proliferation through H19/miR-675 axis.
Quercetin exerts synergetic anti-cancer activity with 10-hydroxy camptothecin.
Bcl-3 is a novel biomarker of renal fibrosis in chronic kidney disease.
FBXW8-dependent degradation of MRFAP1 in anaphase controls mitotic cell death.
Comparative study of macrophages in naked mole rats and ICR mice.
iASPP Is an Antioxidative Factor and Drives Cancer Growth and Drug Resistance by Competing with Nrf2 for Keap1 Binding.
CHST6 mutation screening and endoplasmatic reticulum stress in macular corneal dystrophy.
KSRP specifies monocytic and granulocytic differentiation through regulating miR-129 biogenesis and RUNX1 expression.
A Single-Amino-Acid Substitution at Position 225 in Hemagglutinin Alters the Transmissibility of Eurasian Avian-Like H1N1 Swine Influenza Virus in Guinea Pigs.
Expression and Subcellular Localization of the Kaposi's Sarcoma-Associated Herpesvirus K15P Protein during Latency and Lytic Reactivation in Primary Effusion Lymphoma Cells.
HERP Binds TBK1 To Activate Innate Immunity and Repress Virus Replication in Response to Endoplasmic Reticulum Stress.
Designed inhibitor for nuclear localization signal of polo-like kinase 1 induces mitotic arrest.
The tumor suppressor p53 regulates autophagosomal and lysosomal biogenesis in lung cancer cells by targeting transcription factor EB.
DLX3 mutation negatively regulates odontogenic differentiation of human dental pulp cells.
Cynandione A attenuates neuropathic pain through p38β MAPK-mediated spinal microglial expression of β-endorphin.
Involvement of FMRP in Primary MicroRNA Processing via Enhancing Drosha Translation.
The mechanism of epithelial-mesenchymal transition induced by TGF-β1 in neuroblastoma cells.
E-Prostanoid 3 Receptor Mediates Sprouting Angiogenesis Through Suppression of the Protein Kinase A/β-Catenin/Notch Pathway.
Human recombinant RNASET2-induced inflammatory response and connective tissue remodeling in the medicinal leech.
Fn14 hepatic progenitor cells are associated with liver fibrosis in biliary atresia.
Shen-Yuan-Dan Capsule Inhibiting Inflammatory Reaction by Regulating Insulin Receptor Substrate 1/PI3K/Akt/NF-κB Signaling Pathway in Apoliprotein E Knockout Mice Fed with a High-Fat Diet.
Clinical Significance and Tumor-Suppressive Function of miR-516b in Nonsmall Cell Lung Cancer.
Lethal concentration of perfluoroisobutylene induces acute lung injury in mice mediated via cytokine storm, oxidative stress and apoptosis.
BNIP3 promotes the motility and migration of keratinocyte under hypoxia.
TSA protects H9c2 cells against thapsigargin-induced apoptosis related to endoplasmic reticulum stress-mediated mitochondrial injury.
lncRNA-HIT promotes cell proliferation of non-small cell lung cancer by association with E2F1.
EphrinB-EphB Signaling Induces Hyperalgesia through ERK5/CREB Pathway in Rats.
siRNA-mediated knockdown of ID1 disrupts Nanog- and Oct-4-mediated cancer stem cell-likeness and resistance to chemotherapy in gastric cancer cells.
PCSK9 regulates apoptosis in human lung adenocarcinoma A549 cells via endoplasmic reticulum stress and mitochondrial signaling pathways.
Dihydroartemisin inhibits glioma invasiveness via a ROS to P53 to β-catenin signaling.
Galectin-3 mediates the pulmonary arterial hypertension-induced right ventricular remodeling through interacting with NADPH oxidase 4.
A novel inducible lentiviral system for multi-gene expression with human HSP70 promoter and tetracycline-induced promoter.
Upregulation of the lncRNA Meg3 induces autophagy to inhibit tumorigenesis and progression of epithelial ovarian carcinoma by regulating activity of ATG3.
Atgl gene deletion predisposes to proximal tubule damage by impairing the fatty acid metabolism.
miR-29a regulated ER-positive breast cancer cell growth and invasion and is involved in the insulin signaling pathway.
Fatty acid synthesis is critical for stem cell pluripotency via promoting mitochondrial fission.
MiR-23a-5p modulates mycobacterial survival and autophagy during mycobacterium tuberculosis infection through TLR2/MyD88/NF-κB pathway by targeting TLR2.
A critical role of Hrd1 in the regulation of optineurin degradation and aggresome formation.
Identification and activation of TLR4-mediated signalling pathways by alginate-derived guluronate oligosaccharide in RAW264.7 macrophages.
CRISPR/Cas9 Screens Reveal Epstein-Barr Virus-Transformed B Cell Host Dependency Factors.
Chromium contributes to human bronchial epithelial cell carcinogenesis by activating Gli2 and inhibiting autophagy.
7-O-Geranylquercetin induces apoptosis in gastric cancer cells via ROS-MAPK mediated mitochondrial signaling pathway activation.
Vascular endothelial cells senescence is associated with NOD-like receptor family pyrin domain-containing 3 (NLRP3) inflammasome activation via reactive oxygen species (ROS)/thioredoxin-interacting protein (TXNIP) pathway.
Melatonin synergizes the chemotherapeutic effect of 5-fluorouracil in colon cancer by suppressing PI3K/AKT and NF-κB/iNOS signaling pathways.
Hepatic deletion of X-box binding protein 1 impairs bile acid metabolism in mice.
PBDE-209 exposure damages learning and memory ability in rats potentially through increased autophagy and apoptosis in the hippocampus neuron.
miR-194 functions as a novel modulator of cellular senescence in mouse embryonic fibroblasts.
High mobility group box 1/toll-like receptor 4/myeloid differentiation factor 88 signaling promotes progression of gastric cancer.
MicroRNA-133b is regulated by TAp63 while no gene mutation is present in colorectal cancer.
Knockdown of NUPR1 inhibits the proliferation of glioblastoma cells via ERK1/2, p38 MAPK and caspase-3.
Conditional knockout of Fgf13 in murine hearts increases arrhythmia susceptibility and reveals novel ion channel modulatory roles.
Epidermal CD147 expression plays a key role in IL-22-induced psoriatic dermatitis.
A 3 base pair deletion in TBX1 leads to reduced protein expression and transcriptional activity.
Neuroprotective effects of lycopene in spinal cord injury in rats via antioxidative and anti-apoptotic pathway.
Dectin-2 Deficiency Modulates Th1 Differentiation and Improves Wound Healing After Myocardial Infarction.
Transducin (β)-like 1 X-linked receptor 1 promotes gastric cancer progression via the ERK1/2 pathway.
IL-6 secreted by cancer-associated fibroblasts promotes epithelial-mesenchymal transition and metastasis of gastric cancer via JAK2/STAT3 signaling pathway.
Nuclear localization of Beclin 1 promotes radiation-induced DNA damage repair independent of autophagy.
Anti-tumor effect of evodiamine by inducing Akt-mediated apoptosis in hepatocellular carcinoma.
PPARβ/δ, a Novel Regulator for Vascular Smooth Muscle Cells Phenotypic Modulation and Vascular Remodeling after Subarachnoid Hemorrhage in Rats.
Molecular signaling underlying bulleyaconitine A (BAA)-induced microglial expression of prodynorphin.
Whole-exome sequencing identified a homozygous BRDT mutation in a patient with acephalic spermatozoa.
The promotion of the transformation of quiescent gastric cancer stem cells by IL-17 and the underlying mechanisms.
Combined transplantation of human mesenchymal stem cells and human retinal progenitor cells into the subretinal space of RCS rats.
Cytoskeleton-associated protein 5 and clathrin heavy chain binding regulates spindle assembly in mouse oocytes.
Nonstructural Protein 4 of Porcine Reproductive and Respiratory Syndrome Virus Modulates Cell Surface Swine Leukocyte Antigen Class I Expression by Downregulating β2-Microglobulin Transcription.
Selenomethionine Mitigates Cognitive Decline by Targeting Both Tau Hyperphosphorylation and Autophagic Clearance in an Alzheimer's Disease Mouse Model.
The MLKL Channel in Necroptosis Is an Octamer Formed by Tetramers in a Dyadic Process.
miR-137 downregulates c-kit expression in acute myeloid leukemia.
miR-19 targeting of GSK3β mediates sulforaphane suppression of lung cancer stem cells.
Cr(VI) induces cytotoxicity in vitro through activation of ROS-mediated endoplasmic reticulum stress and mitochondrial dysfunction via the PI3K/Akt signaling pathway.
Simvastatin Inhibits IL-1β-Induced Apoptosis and Extracellular Matrix Degradation by Suppressing the NF-kB and MAPK Pathways in Nucleus Pulposus Cells.
Apobec-1 complementation factor regulates cell migration and apoptosis through Dickkopf1 by acting on its 3' untranslated region in MCF7 cells.
RON and c-Met facilitate metastasis through the ERK signaling pathway in prostate cancer cells.
Cooperation of Musashi-2, Numb, MDM2, and P53 in drug resistance and malignant biology of pancreatic cancer.
Role of the Wnt/β-catenin signaling pathway in inducing apoptosis and renal fibrosis in 5/6-nephrectomized rats.
Overexpressed miR-9 promotes tumor metastasis via targeting E-cadherin in serous ovarian cancer.
Nucleotide-binding oligomerization domain (NOD) signaling defects and cell death susceptibility cannot be uncoupled in X-linked inhibitor of apoptosis (XIAP)-driven inflammatory disease.
Loss of the novel mitochondrial protein FAM210B promotes metastasis via PDK4-dependent metabolic reprogramming.
Upconversion nanoparticle-mediated photodynamic therapy induces autophagy and cholesterol efflux of macrophage-derived foam cells via ROS generation.
Erythropoietin activates SIRT1 to protect human cardiomyocytes against doxorubicin-induced mitochondrial dysfunction and toxicity.
(-)-Epigallocatechin-3-Gallate Inhibits Colorectal Cancer Stem Cells by Suppressing Wnt/β-Catenin Pathway.
miR-181d/MALT1 regulatory axis attenuates mesenchymal phenotype through NF-κB pathways in glioblastoma.
AQP9-induced cell cycle arrest is associated with RAS activation and improves chemotherapy treatment efficacy in colorectal cancer.
Total Flavonoids of Drynariae Rhizoma Prevent Bone Loss Induced by Hindlimb Unloading in Rats.
Chemokine receptor CXCR4 regulates CaMKII/CREB pathway in spinal neurons that underlies cancer-induced bone pain.
Long-Term Dietary Supplementation with Selenium-Enriched Yeast Improves Cognitive Impairment, Reverses Synaptic Deficits, and Mitigates Tau Pathology in a Triple Transgenic Mouse Model of Alzheimer's Disease.
Expression of estrogen receptors and androgen receptor and their clinical significance in gastric cancer.
Clonorchis sinensis lysophospholipase A upregulates IL-25 expression in macrophages as a potential pathway to liver fibrosis.
RUFY3 interaction with FOXK1 promotes invasion and metastasis in colorectal cancer.
CDK4 protein is degraded by anaphase-promoting complex/cyclosome in mitosis and reaccumulates in early G(1) phase to initiate a new cell cycle in HeLa cells.
Quantitative Proteomic Analysis of Mosquito C6/36 Cells Reveals Host Proteins Involved in Zika Virus Infection.
BST2 confers cisplatin resistance via NF-κB signaling in nasopharyngeal cancer.
The phosphatase Pgam5 antagonizes Wnt/β-Catenin signaling in embryonic anterior-posterior axis patterning.
Promoting tumorigenesis in nasopharyngeal carcinoma, NEDD8 serves as a potential theranostic target.
cMyBP-C was decreased via KLHL3-mediated proteasomal degradation in congenital heart diseases.
Autocrine Prolactin Stimulates Endometrial Carcinoma Growth and Metastasis and Reduces Sensitivity to Chemotherapy.
Wogonin mitigates nonalcoholic fatty liver disease via enhancing PPARα/AdipoR2, in vivo and in vitro.
Garlic-derived organosulfur compound exerts antitumor efficacy via activation of MAPK pathway and modulation of cytokines in SGC-7901 tumor-bearing mice.
Timing of autophagy and apoptosis during posterior silk gland degeneration in Bombyx mori.
RUVBL1-ITFG1 interaction is required for collective invasion in breast cancer.
Correlation study of DNA methylation of WNT6 gene with osteosarcoma in children.
Bacterial effector NleL promotes enterohemorrhagic E. coli-induced attaching and effacing lesions by ubiquitylating and inactivating JNK.
USP19 suppresses cellular type I interferon signaling by targeting TRAF3 for deubiquitination.
Cigarette smoke extract induces EGFR-TKI resistance via promoting EGFR signaling pathway and ROS generation in NSCLC cell lines.
5T4-specific chimeric antigen receptor modification promotes the immune efficacy of cytokine-induced killer cells against nasopharyngeal carcinoma stem cell-like cells.
SNORD47, a box C/D snoRNA, suppresses tumorigenesis in glioblastoma.
Down-regulation of UBC9 increases the sensitivity of hepatocellular carcinoma to doxorubicin.
Fork Head Box Class O1 (FOXO1) Activates Bim Expression to Mediate Cardiac Apoptosis in Chronic Intermittent Hypoxia-Induced Cardiac Hypertrophy.
Correction: Phosphoglycerate mutase 1 regulates dNTP pool and promotes homologous recombination repair in cancer cells.
Autophagosome maturation mediated by Rab7 contributes to neuroprotection of hypoxic preconditioning against global cerebral ischemia in rats.
FOXQ1 regulates senescence-associated inflammation via activation of SIRT1 expression.
KMT2A promotes melanoma cell growth by targeting hTERT signaling pathway.
A hydrophobic residue in the TALE homeodomain of PBX1 promotes epithelial-to-mesenchymal transition of gastric carcinoma.
Novel function of pregnancy-associated plasma protein A: promotes endometrium receptivity by up-regulating N-fucosylation.
Hydrogen sulfide attenuates cardiac injury in takotsubo cardiomyopathy by alleviating oxidative stress.
Feeding influences adipose tissue responses to exercise in overweight men.
Resveratrol Pretreatment Decreases Ischemic Injury and Improves Neurological Function Via Sonic Hedgehog Signaling After Stroke in Rats.
H/ACA Box Small Nucleolar RNA 7A Promotes the Self-Renewal of Human Umbilical Cord Mesenchymal Stem Cells.
Runx2, a novel regulator for goblet cell differentiation and asthma development.
Cigarette smoke extract-induced proliferation of normal human urothelial cells via the MAPK/AP-1 pathway.
Anti-inflammatory and neuroprotective effects of sanguinarine following cerebral ischemia in rats.
Forkhead box P3 regulates ARHGAP15 expression and affects migration of glioma cells through the Rac1 signaling pathway.
Long-term exposure to a 'safe' dose of bisphenol A reduced protein acetylation in adult rat testes.
Mitomycin C-treated human-induced pluripotent stem cells as a safe delivery system of gold nanorods for targeted photothermal therapy of gastric cancer.
Identification of a novel missense mutation of MIP in a Chinese family with congenital cataracts by target region capture sequencing.
The RhoA/ROCK Pathway Ameliorates Adhesion and Inflammatory Infiltration Induced by AGEs in Glomerular Endothelial Cells.
Endothelial microparticles are increased in congenital heart diseases and contribute to endothelial dysfunction.
Genetic and epigenetic silencing of mircoRNA-506-3p enhances COTL1 oncogene expression to foster non-small lung cancer progression.
Metformin Induces Growth Inhibition and Cell Cycle Arrest by Upregulating MicroRNA34a in Renal Cancer Cells.
DAZ-interacting Protein 1 (Dzip1) Phosphorylation by Polo-like Kinase 1 (Plk1) Regulates the Centriolar Satellite Localization of the BBSome Protein during the Cell Cycle.
Resveratrol reverses Doxorubicin resistance by inhibiting epithelial-mesenchymal transition (EMT) through modulating PTEN/Akt signaling pathway in gastric cancer.
Hormetic effect of panaxatriol saponins confers neuroprotection in PC12 cells and zebrafish through PI3K/AKT/mTOR and AMPK/SIRT1/FOXO3 pathways.
Up-regulation of syncytin-1 contributes to TNF-α-enhanced fusion between OSCC and HUVECs partly via Wnt/β-catenin-dependent pathway.
B7-H3 regulates lipid metabolism of lung cancer through SREBP1-mediated expression of FASN.
Highly expressed lncRNA CCND2-AS1 promotes glioma cell proliferation through Wnt/β-catenin signaling.
Secreted miR-27a Induced by Cyclic Stretch Modulates the Proliferation of Endothelial Cells in Hypertension via GRK6.
Identification of TDP-43 as an oncogene in melanoma and its function during melanoma pathogenesis.
A comprehensive platform for the analysis of ubiquitin-like protein modifications using in vivo biotinylation.
Melatonin ameliorates amygdala-dependent emotional memory deficits in Tg2576 mice by up-regulating the CREB/c-Fos pathway.
[Changes of endogenous Spastin expression after sciatic nerve injury in rats].
Retromer- and WASH-dependent sorting of nutrient transporters requires a multivalent interaction network with ANKRD50.
Contractile forces at tricellular contacts modulate epithelial organization and monolayer integrity.
CRB3 regulates contact inhibition by activating the Hippo pathway in mammary epithelial cells.
TRIM52: A nuclear TRIM protein that positively regulates the nuclear factor-kappa B signaling pathway.
MicroRNA-22 regulates inflammation and angiogenesis via targeting VE-cadherin.
Upregulation of miR-146a by YY1 depletion correlates with delayed progression of prostate cancer.
MicroRNA-503-5p inhibits stretch-induced osteogenic differentiation and bone formation.
Expression of glia maturation factor γ is associated with colorectal cancer metastasis and its downregulation suppresses colorectal cancer cell migration and invasion in vitro.
Long Noncoding RNA DANCR Is a Positive Regulator of Proliferation and Chondrogenic Differentiation in Human Synovium-Derived Stem Cells.
Diethylstilbestrol activates CatSper and disturbs progesterone actions in human spermatozoa.
Kukoamine A Prevents Radiation-Induced Neuroinflammation and Preserves Hippocampal Neurogenesis in Rats by Inhibiting Activation of NF-κB and AP-1.
Phosphoglycerate mutase 1 regulates dNTP pool and promotes homologous recombination repair in cancer cells.
The effect of nuclear factor erythroid 2-related factor/antioxidant response element signalling pathway in the lanthanum chloride-induced impairment of learning and memory in rats.
GAPDH-mediated posttranscriptional regulations of sodium channel Scn1a and Scn3a genes under seizure and ketogenic diet conditions.
Triggering of apoptosis in osteosarcoma cells by graphene/single-walled carbon nanotube hybrids via the ROS-mediated mitochondrial pathway.
Quercetin induces autophagy via FOXO1-dependent pathways and autophagy suppression enhances quercetin-induced apoptosis in PASMCs in hypoxia.
Up-Regulation of RFC3 Promotes Triple Negative Breast Cancer Metastasis and is Associated With Poor Prognosis Via EMT.
LncRNA AK023948 is a positive regulator of AKT.
Decreased expression of STING predicts poor prognosis in patients with gastric cancer.
A novel peptide, 9R-P201, strongly inhibits the viability, proliferation and migration of liver cancer HepG2 cells and induces apoptosis by down-regulation of FoxM1 expression.
Luteolin suppresses gastric cancer progression by reversing epithelial-mesenchymal transition via suppression of the Notch signaling pathway.
HnRNP-L mediates bladder cancer progression by inhibiting apoptotic signaling and enhancing MAPK signaling pathways.
Simvastatin suppresses the DNA replication licensing factor MCM7 and inhibits the growth of tamoxifen-resistant breast cancer cells.
Method for Dual Viral Vector Mediated CRISPR-Cas9 Gene Disruption in Primary Human Endothelial Cells.
RELM-β promotes human pulmonary artery smooth muscle cell proliferation via FAK-stimulated surviving.
Sinomenine hydrochloride attenuates the proliferation, migration, invasiveness, angiogenesis and epithelial-mesenchymal transition of clear-cell renal cell carcinoma cells via targeting Smad in vitro.
Quantitative determination, principal component analysis and discriminant analysis of eight marker compounds in crude and sweated Dipsaci Radix by HPLC-DAD.
Long non-coding RNA CASC15 is upregulated in hepatocellular carcinoma and facilitates hepatocarcinogenesis.
MTA-induced Notch activation enhances the proliferation of human dental pulp cells by inhibiting autophagic flux.
Productive HBV infection of well-differentiated, hNTCP-expressing human hepatoma-derived (Huh7) cells.
Glucose potentiates β-cell function by inducing Tph1 expression in rat islets.
MicroRNA-200c impairs uterine receptivity formation by targeting FUT4 and α1,3-fucosylation.
MiR-616 promotes proliferation and inhibits apoptosis in glioma cells by suppressing expression of SOX7 via the Wnt signaling pathway.
Expression of PTEN-long mediated by CRISPR/Cas9 can repress U87 cell proliferation.
POSH participates in epileptogenesis by increasing the surface expression of the NMDA receptor: a promising therapeutic target for epilepsy.
The reproductive toxicology of male SD rats after PM(2.5) exposure mediated by the stimulation of endoplasmic reticulum stress.
Autophagy is essential for flavopiridol‑induced cytotoxicity against MCF‑7 breast cancer cells.
20-Hydroxyeicosatetraenoic acid regulates the expression of Nedd4‑2 in kidney and liver through a neddylation modification pathway.
Baicalin alleviates H2O2‑induced injury of H9c2 cardiomyocytes through suppression of the Wnt/β‑catenin signaling pathway.
Propofol regulates the expression of TLR4 through miR‑21 in human umbilical vein endothelial cells.
EPAC-RAP1 Axis-Mediated Switch in the Response of Primary and Metastatic Melanoma to Cyclic AMP.
Molecular mechanisms in vascular injury induced by hypertension: Expression and role of microRNA-34a.
Alginate enhances Toll-like receptor 4-mediated phagocytosis by murine RAW264.7 macrophages.
Biologico-clinical significance of DNMT3A variants expression in acute myeloid leukemia.
Upregulation of miR-126-3p promotes human saphenous vein endothelial cell proliferation in vitro and prevents vein graft neointimal formation ex vivo and in vivo.
A novel KCND3 mutation associated with early-onset lone atrial fibrillation.
EGFR expression in patients with stage III colorectal cancer after adjuvant chemotherapy and on cancer cell function.
Respiratory Syncytial Virus Nonstructural Protein 1 Blocks Glucocorticoid Receptor Nuclear Translocation by Targeting IPO13 and May Account for Glucocorticoid Insensitivity.
Interactions between GHRH and GABAARs in the brains of patients with epilepsy and in animal models of epilepsy.
Morin enhances hepatic Nrf2 expression in a liver fibrosis rat model.
ICAM-1 regulates macrophage polarization by suppressing MCP-1 expression via miR-124 upregulation.
Disruption of the c-Myc/miR-200b-3p/PRDX2 regulatory loop enhances tumor metastasis and chemotherapeutic resistance in colorectal cancer.
Bifunctional enzyme ATIC promotes propagation of hepatocellular carcinoma by regulating AMPK-mTOR-S6 K1 signaling.
Mammalian Numb protein antagonizes Notch by controlling postendocytic trafficking of the Notch ligand Delta-like 4.
Interleukin-22 participates in the inflammatory process of vitiligo.
HRD1 prevents apoptosis in renal tubular epithelial cells by mediating eIF2α ubiquitylation and degradation.
Human Cytomegalovirus Encoded miR-US25-1-5p Attenuates CD147/EMMPRIN-Mediated Early Antiviral Response.
Bisphenol a induces autophagy and apoptosis concurrently involving the Akt/mTOR pathway in testes of pubertal SD rats.
Looping-out mechanism for resolution of replicative stress at telomeres.
MicroRNA-149 contributes to scarless wound healing by attenuating inflammatory response.
Protective effect of lutein on ARPE-19 cells upon H2O2-induced G2/M arrest.
Intermedin improves cardiac function and sympathetic neural remodeling in a rat model of post myocardial infarction heart failure.
The effects of hyperoside on apoptosis and the expression of Fas/FasL and survivin in SW579 human thyroid squamous cell carcinoma cell line.
Treatment mechanism of matrine in combination with irinotecan for colon cancer.
HRS plays an important role for TLR7 signaling to orchestrate inflammation and innate immunity upon EV71 infection.
Calpain Inhibition Is Protective in Machado-Joseph Disease Zebrafish Due to Induction of Autophagy.
The impact of p53 on the early stage replication of retrovirus.
Platelet Derived Growth Factor Alpha (PDGFRα) Induces the Activation of Cardiac Fibroblasts by Activating c-Kit.
TIMELESS confers cisplatin resistance in nasopharyngeal carcinoma by activating the Wnt/β-catenin signaling pathway and promoting the epithelial mesenchymal transition.
CO-releasing molecules-2 attenuates ox-LDL-induced injury in HUVECs by ameliorating mitochondrial function and inhibiting Wnt/β-catenin pathway.
A Chinese herbal formula, Jian-Pi-Yi-Shen decoction, improves muscle atrophy via regulating mitochondrial quality control process in 5/6 nephrectomised rats.
Mediator MED23 Links Pigmentation and DNA Repair through the Transcription Factor MITF.
Activation of Nrf2/ARE signaling pathway attenuates lanthanum chloride induced injuries in primary rat astrocytes.
Seneca Valley Virus Suppresses Host Type I Interferon Production by Targeting Adaptor Proteins MAVS, TRIF, and TANK for Cleavage.
microRNA-451-modulated hnRNP A1 takes a part in granulocytic differentiation regulation and acute myeloid leukemia.
Neuronal zinc-α2-glycoprotein is decreased in temporal lobe epilepsy in patients and rats.
Flavonoid glycosides isolated from Epimedium brevicornum and their estrogen biosynthesis-promoting effects.
AMPK Serves as a Therapeutic Target Against Anemia of Inflammation.
Role of RAS/Wnt/β-catenin axis activation in the pathogenesis of podocyte injury and tubulo-interstitial nephropathy.
Transcription factor GATA3 expression is induced by GLS2 overexpression in a glioblastoma cell line but is GLS2-independent in patient-derived glioblastoma.
The role of metastasis-associated in colon cancer 1 (MACC1) in endometrial carcinoma tumorigenesis and progression.
Isoquercetin Ameliorates Cerebral Impairment in Focal Ischemia Through Anti-Oxidative, Anti-Inflammatory, and Anti-Apoptotic Effects in Primary Culture of Rat Hippocampal Neurons and Hippocampal CA1 Region of Rats.
The protective effect of dopamine on ventilator-induced lung injury via the inhibition of NLRP3 inflammasome.
Down-regulation of Pin1 in Temporal Lobe Epilepsy Patients and Mouse Model.
Protective effect of naringin against the LPS-induced apoptosis of PC12 cells: Implications for the treatment of neurodegenerative disorders.
miR-92a promotes tumor growth of osteosarcoma by targeting PTEN/AKT signaling pathway.
miR-30a radiosensitizes non-small cell lung cancer by targeting ATF1 that is involved in the phosphorylation of ATM.
Low expression of TMEM67 is a critical predictor of poor prognosis in human urothelial carcinoma of the bladder.
The Selective Serotonin Reuptake Inhibitor Fluoxetine Directly Inhibits Osteoblast Differentiation and Mineralization During Fracture Healing in Mice.
Interleukin 6 induces cell proliferation of clear cell renal cell carcinoma by suppressing hepaCAM via the STAT3-dependent up-regulation of DNMT1 or DNMT3b.
Histone deacetylase inhibitor apicidin increases expression of the α-secretase ADAM10 through transcription factor USF1-mediated mechanisms.
Blocking the recruitment of naive CD4(+) T cells reverses immunosuppression in breast cancer.
Non-hemolytic enterotoxin of Bacillus cereus induces apoptosis in Vero cells.
Activation of ATP-sensitive potassium channel by iptakalim normalizes stress-induced HPA axis disorder and depressive behaviour by alleviating inflammation and oxidative stress in mouse hypothalamus.
GP73 represses host innate immune response to promote virus replication by facilitating MAVS and TRAF6 degradation.
Quercetin exerts preventive, ameliorative and prophylactic effects on cadmium chloride - induced oxidative stress in the uterus and ovaries of female Wistar rats.
Induction of pro-inflammatory genes by serum amyloid A1 in human amnion fibroblasts.
Bone marrow-derived mesenchymal stem cells (BMSCs) repair acute necrotized pancreatitis by secreting microRNA-9 to target the NF-κB1/p50 gene in rats.
HMGCS2 promotes autophagic degradation of the amyloid-β precursor protein through ketone body-mediated mechanisms.
Atorvastatin prevents Angiotensin II induced myocardial hypertrophy in vitro via CCAAT/enhancer-binding protein β.
DNA replication licensing factor Cdc6 and Plk4 kinase antagonistically regulate centrosome duplication via Sas-6.
CtBP2 overexpression promotes tumor cell proliferation and invasion in gastric cancer and is associated with poor prognosis.
Amelioration of amyloid-β-induced deficits by DcR3 in an Alzheimer's disease model.
Exenatide improves liver mitochondrial dysfunction and insulin resistance by reducing oxidative stress in high fat diet-induced obese mice.
Tumor necrosis factor receptor 2/AKT and ERK signaling pathways contribute to the switch from fibroblasts to CAFs by progranulin in microenvironment of colorectal cancer.
Satb2 Ablation Impairs Hippocampus-Based Long-Term Spatial Memory and Short-Term Working Memory and Immediate Early Genes (IEGs)-Mediated Hippocampal Synaptic Plasticity.
Identification, expression pattern and functional characterization of As-kip2 in diapause embryo restarting process of Artemia sinica.
In vitro biomimetic platforms featuring a perfusion system and 3D spheroid culture promote the construction of tissue-engineered corneal endothelial layers.
MeCP2 regulated glycogenes contribute to proliferation and apoptosis of gastric cancer cells.
Autophagic Degradation of Collagen 1A1 by Cortisol in Human Amnion Fibroblasts.
Knockdown of Sall4 inhibits intrahepatic cholangiocarcinoma cell migration and invasion in ICC-9810 cells.
Downregulating hypoxia-inducible factor-1α expression with perfluorooctyl-bromide nanoparticles reduces early brain injury following experimental subarachnoid hemorrhage in rats.
Down-regulation of long non-coding RNA FOXD3 antisense RNA 1 (FOXD3-AS1) inhibits cell proliferation, migration, and invasion in malignant glioma cells.
Upregulation of long non-coding RNA LINC00152 by SP1 contributes to gallbladder cancer cell growth and tumor metastasis via PI3K/AKT pathway.
Autophagy postpones apoptotic cell death in PRRSV infection through Bad-Beclin1 interaction.
Yin-Chen-Hao Tang Attenuates Severe Acute Pancreatitis in Rat: An Experimental Verification of In silico Network Target Prediction.
Exogenous Hydrogen Sulfide Attenuates High Glucose-Induced Cardiotoxicity by Inhibiting NLRP3 Inflammasome Activation by Suppressing TLR4/NF-κB Pathway in H9c2 Cells.
Parthenolide Induces Reactive Oxygen Species-Mediated Autophagic Cell Death in Human Osteosarcoma Cells.
FBXO6-Mediated Ubiquitination and Degradation of Ero1L Inhibits Endoplasmic Reticulum Stress-Induced Apoptosis.
Effect of Type I Diabetes on the Proteome of Mouse Oocytes.
Similar efficacy from specific and non-specific mineralocorticoid receptor antagonist treatment of muscular dystrophy mice.
N-Stearoyl-L-Tyrosine Inhibits the Senescence of Neural Stem/Progenitor Cells Induced by Aβ 1-42 via the CB2 Receptor.
Neurotrophic Effect of Adipose Tissue-Derived Stem Cells on Erectile Function Recovery by Pigment Epithelium-Derived Factor Secretion in a Rat Model of Cavernous Nerve Injury.
HIV-1 Tat Regulates Occludin and Aβ Transfer Receptor Expression in Brain Endothelial Cells via Rho/ROCK Signaling Pathway.
MiR-20a-5p represses multi-drug resistance in osteosarcoma by targeting the KIF26B gene.
Forsythoside A Inhibits BVDV Replication via TRAF2-Dependent CD28-4-1BB Signaling in Bovine PBMCs.
Finasteride Enhances the Generation of Human Myeloid-Derived Suppressor Cells by Up-Regulating the COX2/PGE2 Pathway.
Hepatitis B Virus Stimulated Fibronectin Facilitates Viral Maintenance and Replication through Two Distinct Mechanisms.
Electroacupuncture Promotes Remyelination after Cuprizone Treatment by Enhancing Myelin Debris Clearance.
Low-Dose Endothelial-Monocyte-Activating Polypeptide-II Induced Autophagy by Down-Regulating miR-20a in U-87 and U-251 Glioma Cells.
Fluoride induced endoplasmic reticulum stress and calcium overload in ameloblasts.
Effects of ZnO nanoparticles on perfluorooctane sulfonate induced thyroid-disrupting on zebrafish larvae.
Curcumin Attenuated Bupivacaine-Induced Neurotoxicity in SH-SY5Y Cells Via Activation of the Akt Signaling Pathway.
Evodiamine exerts anti-tumor effects against hepatocellular carcinoma through inhibiting β-catenin-mediated angiogenesis.
Angiopoietin-like protein 2 expression is suppressed by angiotensin II via the angiotensin II type 1 receptor in rat cardiomyocytes.
Simultaneous inhibition of the ubiquitin-proteasome system and autophagy enhances apoptosis induced by ER stress aggravators in human pancreatic cancer cells.
Alternative splicing of spleen tyrosine kinase differentially regulates colorectal cancer progression.
Structure-based discovery of two antiviral inhibitors targeting the NS3 helicase of Japanese encephalitis virus.
Regulation of PCGEM1 by p54/nrb in prostate cancer.
Epigenomic profiling of primary gastric adenocarcinoma reveals super-enhancer heterogeneity.
Control of cortex development by ULK4, a rare risk gene for mental disorders including schizophrenia.
Selenomethionine Ameliorates Neuropathology in the Olfactory Bulb of a Triple Transgenic Mouse Model of Alzheimer's Disease.
TDP-43 aggregation mirrors TDP-43 knockdown, affecting the expression levels of a common set of proteins.
TRIM52 inhibits Japanese Encephalitis Virus replication by degrading the viral NS2A.
Polyphenols from hawthorn peels and fleshes differently mitigate dyslipidemia, inflammation and oxidative stress in association with modulation of liver injury in high fructose diet-fed mice.
Reversal of cisplatin resistance in non-small cell lung cancer stem cells by Taxus chinensis var.
Triplex structures induce DNA double strand breaks via replication fork collapse in NER deficient cells.
miR-106a promotes cardiac hypertrophy by targeting mitofusin 2.
SIRT1 activator ameliorates the renal tubular injury induced by hyperglycemia in vivo and in vitro via inhibiting apoptosis.
Prognostic value of mixed lineage kinase domain-like protein expression in the survival of patients with gastric caner.
Neuroprotective Effects of Dexmedetomidine Against Hypoxia-Induced Nervous System Injury are Related to Inhibition of NF-κB/COX-2 Pathways.
Inhibition of Lysyl Oxidase by Cortisol Regeneration in Human Amnion: Implications for Rupture of Fetal Membranes.
Nanoparticle-facilitated autophagy inhibition promotes the efficacy of chemotherapeutics against breast cancer stem cells.
Long non-coding RNA H19 regulates FOXM1 expression by competitively binding endogenous miR-342-3p in gallbladder cancer.
Golgi protein 73 facilitates the interaction of hepatitis C virus NS5A with apolipoprotein E to promote viral particle secretion.
Dioscin attenuates gastric ischemia/reperfusion injury through the down-regulation of PKC/ERK1/2 signaling via PKCα and PKCβ2 inhibition.
Depletion of thymopoietin inhibits proliferation and induces cell cycle arrest/apoptosis in glioblastoma cells.
Afamin promotes glucose metabolism in papillary thyroid carcinoma.
Olig2-Targeted G-Protein-Coupled Receptor Gpr17 Regulates Oligodendrocyte Survival in Response to Lysolecithin-Induced Demyelination.
Cleavage and polyadenylation specific factor 4 targets NF-κB/cyclooxygenase-2 signaling to promote lung cancer growth and progression.
25-Hydroxycholesterol impairs endothelial function and vasodilation by uncoupling and inhibiting endothelial nitric oxide synthase.
Tim-4 protects mice against lipopolysaccharide-induced endotoxic shock by suppressing the NF-κB signaling pathway.
MicroRNA124 Regulated Neurite Elongation by Targeting OSBP.
Transplantation of Human Urine-Derived Stem Cells Transfected with Pigment Epithelium-Derived Factor to Protect Erectile Function in a Rat Model of Cavernous Nerve Injury.
Cyclooxygenase-2 is associated with malignant phenotypes in human lung cancer.
Sargassum fusiforme polysaccharides activate antioxidant defense by promoting Nrf2-dependent cytoprotection and ameliorate stress insult during aging.
Promotive effects of bone morphogenetic protein 2 on angiogenesis in hepatocarcinoma via multiple signal pathways.
NR4A1 Knockdown Suppresses Seizure Activity by Regulating Surface Expression of NR2B.
Quantitative proteomics reveals molecular mechanism of gamabufotalin and its potential inhibition on Hsp90 in lung cancer.
Keap1 hypomorphism protects against ischemic and obstructive kidney disease.
Lithium promotes DNA stability and survival of ischemic retinal neurocytes by upregulating DNA ligase IV.
microRNA-23a, -27a and -24 synergistically regulate JAK1/Stat3 cascade and serve as novel therapeutic targets in human acute erythroid leukemia.
Neutrophil extracellular traps are indirectly triggered by lipopolysaccharide and contribute to acute lung injury.
Activation of the RLR/MAVS Signaling Pathway by the L Protein of Mopeia Virus.
MicroRNA deep sequencing in two adult stem cell populations identifies miR-501 as a novel regulator of myosin heavy chain during muscle regeneration.
Phosphorylation of STAT2 on serine-734 negatively regulates the IFN-α-induced antiviral response.
17β-Estradiol Inhibites Tumor Necrosis Factor-α Induced Apoptosis of Human Nucleus Pulposus Cells via the PI3K/Akt Pathway.
Deletion of Pr130 Interrupts Cardiac Development in Zebrafish.
Downregulation of myosin VI reduced cell growth and increased apoptosis in human colorectal cancer.
Pristimerin overcomes adriamycin resistance in breast cancer cells through suppressing Akt signaling.
Downregulation of ATOH8 induced by EBV-encoded LMP1 contributes to the malignant phenotype of nasopharyngeal carcinoma.
MicroRNA-24 promotes 3T3-L1 adipocyte differentiation by directly targeting the MAPK7 signaling.
RBM4 promotes neuronal differentiation and neurite outgrowth by modulating Numb isoform expression.
CGP57380 enhances efficacy of RAD001 in non-small cell lung cancer through abrogating mTOR inhibition-induced phosphorylation of eIF4E and activating mitochondrial apoptotic pathway.
MiR-146a affects the alteration in myeloid differentiation induced by hydroquinone in human CD34(+) hematopoietic progenitor cells and HL-60 cells.
Transcription factor Fli-1 positively regulates lipopolysaccharide-induced interleukin-27 production in macrophages.
Glutathione S-transferase SlGSTE1 in Spodoptera litura may be associated with feeding adaptation of host plants.
The protective effect of melatonin on smoke-induced vascular injury in rats and humans: a randomized controlled trial.
Akt inhibitor MK-2206 enhances the effect of cisplatin in gastric cancer cells.
Swine TRIM21 restricts FMDV infection via an intracellular neutralization mechanism.
Significance of the NOR1-FOXA1/HDAC2-Slug regulatory network in epithelial-mesenchymal transition of tumor cells.
Bromodomain-containing protein 7 (BRD7) as a potential tumor suppressor in hepatocellular carcinoma.
TGF-β1 activates the canonical NF-κB signaling to promote cell survival and proliferation in dystrophic muscle fibroblasts in vitro.
REST alleviates neurotoxic prion peptide-induced synaptic abnormalities, neurofibrillary degeneration and neuronal death partially via LRP6-mediated Wnt-β-catenin signaling.
Suppression of prostate cancer progression by cancer cell stemness inhibitor napabucasin.
A novel conditional gene silencing method using a tumor-specific and heat-inducible siRNA system.
Mitigation of tight junction protein dysfunction in lung microvascular endothelial cells with pitavastatin.
Oleanolic acid inhibits cell survival and proliferation of prostate cancer cells in vitro and in vivo through the PI3K/Akt pathway.
Recombinant adeno-associated virus-delivered anginex inhibits angiogenesis and growth of HUVECs by regulating the Akt, JNK and NF-κB signaling pathways.
Coordinate regulatory osteogenesis effects of icariin, timosaponin B II and ferulic acid from traditional Chinese medicine formulas on UMR-106 osteoblastic cells and osteoblasts in neonatal rat calvaria cultures.
Downregulation of stathmin 1 in human gallbladder carcinoma inhibits tumor growth in vitro and in vivo.
HuR-regulated lncRNA NEAT1 stability in tumorigenesis and progression of ovarian cancer.
Midgut epithelium in molting silkworm: A fine balance among cell growth, differentiation, and survival.
High TXNDC5 expression predicts poor prognosis in renal cell carcinoma.
MicroRNA-124 negatively regulates LPS-induced TNF-α production in mouse macrophages by decreasing protein stability.
Berberine in combination with cisplatin suppresses breast cancer cell growth through induction of DNA breaks and caspase-3-dependent apoptosis.
Malignant gliomas induce and exploit astrocytic mesenchymal-like transition by activating canonical Wnt/β-catenin signaling.
Comparative Effects of Bile Diversion and Duodenal-Jejunal Bypass on Glucose and Lipid Metabolism in Male Diabetic Rats.
Influence of orally fed a select mixture of Bacillus probiotics on intestinal T-cell migration in weaned MUC4 resistant pigs following Escherichia coli challenge.
Persisting and Increasing Neutrophil Infiltration Associates with Gastric Carcinogenesis and E-cadherin Downregulation.
Polyhydroxycurcuminoids but not curcumin upregulate neprilysin and can be applied to the prevention of Alzheimer's disease.
Homologous recombination-dependent repair of telomeric DSBs in proliferating human cells.
Total saponins isolated from Radix et Rhizoma Leonticis suppresses tumor cells growth by regulation of PI3K/Akt/mTOR and p38 MAPK pathways.
Loss of TIM50 suppresses proliferation and induces apoptosis in breast cancer.
Knockdown of protein phosphatase 5 inhibits ovarian cancer growth in vitro.
DNA Methylation mediated down-regulating of MicroRNA-33b and its role in gastric cancer.
Regulation of SCN3B/scn3b by Interleukin 2 (IL-2): IL-2 modulates SCN3B/scn3b transcript expression and increases sodium current in myocardial cells.
miR-183 regulates autophagy and apoptosis in colorectal cancer through targeting of UVRAG.
A simple multi-well stretching device to induce inflammatory responses of vascular endothelial cells.
Differential requirement of bone morphogenetic protein receptors Ia (ALK3) and Ib (ALK6) in early embryonic patterning and neural crest development.
Increased expression of copine VI in patients with refractory epilepsy and a rat model.
Ginsenoside Rg3 inhibits epithelial-mesenchymal transition (EMT) and invasion of lung cancer by down-regulating FUT4.
A novel combination of oridonin and valproic acid in enhancement of apoptosis induction of HL-60 leukemia cells.
Effect of LYRM1 knockdown on proliferation, apoptosis, differentiation and mitochondrial function in the P19 cell model of cardiac differentiation in vitro.
NudC regulates actin dynamics and ciliogenesis by stabilizing cofilin 1.
Role of KIF2A in the progression and metastasis of human glioma.
Nanocomplexes from RGD-modified generation 1.0 polyamidoamine based copolymers used for intravascular gene release to prevent restenosis.
PGRN promotes migration and invasion of epithelial ovarian cancer cells through an epithelial mesenchymal transition program and the activation of cancer associated fibroblasts.
CREB-binding protein regulates lung cancer growth by targeting MAPK and CPSF4 signaling pathway.
MicroRNA-372 inhibits endometrial carcinoma development by targeting the expression of the Ras homolog gene family member C (RhoC).
RNF135, RING finger protein, promotes the proliferation of human glioblastoma cells in vivo and in vitro via the ERK pathway.
Decreased TPD52 expression is associated with poor prognosis in primary hepatocellular carcinoma.
Thrombospondin-1 might be a therapeutic target to suppress RB cells by regulating the DNA double-strand breaks repair.
Lactobacillus rhamnosus GR-1 Ameliorates Escherichia coli-Induced Inflammation and Cell Damage via Attenuation of ASC-Independent NLRP3 Inflammasome Activation.
DLX3 negatively regulates osteoclastic differentiation through microRNA-124.
Mammalian cells lacking either the cotranslational or posttranslocational oligosaccharyltransferase complex display substrate-dependent defects in asparagine linked glycosylation.
Effects of total flavonoids from Drynariae Rhizoma prevent bone loss in vivo and in vitro.
Life-cycle exposure to BDE-47 results in thyroid endocrine disruption to adults and offsprings of zebrafish (Danio rerio).
Angelicin inhibits human lung carcinoma A549 cell growth and migration through regulating JNK and ERK pathways.
Developmental regulation of CYP3A4 and CYP3A7 in Chinese Han population.
The lncRNA MALAT1 functions as a competing endogenous RNA to regulate MCL-1 expression by sponging miR-363-3p in gallbladder cancer.
Oligosaccharyltransferase inhibition induces senescence in RTK-driven tumor cells.
Interaction between endogenous carbon monoxide and hydrogen sulfide in the mechanism of gastroprotection against acute aspirin-induced gastric damage.
Vam3 ameliorates total body irradiation-induced hematopoietic system injury partly by regulating the expression of Nrf2-targeted genes.
Repression of CDKN2C caused by PML/RARα binding promotes the proliferation and differentiation block in acute promyelocytic leukemia.
Senescence: novel insight into DLX3 mutations leading to enhanced bone formation in Tricho-Dento-Osseous syndrome.
Rab8a/Rab11a regulate intercellular communications between neural cells via tunneling nanotubes.
Elevated expression of ZNF217 promotes prostate cancer growth by restraining ferroportin-conducted iron egress.
Unc-5 homolog B (UNC5B) is one of the key downstream targets of N-α-Acetyltransferase 10 (Naa10).
Up-regulation of granzyme B and perforin by staphylococcal enterotoxin C2 mutant induces enhanced cytotoxicity in Hepa1-6 cells.
Attribution of NKG2DL to the inhibition of early stage allogeneic tumors in mice.
ERK-mediated NF-κB activation through ASIC1 in response to acidosis.
Growth Differentiation Factor-15-Induced Contractile Activity and Extracellular Matrix Production in Human Trabecular Meshwork Cells.
Myeloid cells are capable of synthesizing aldosterone to exacerbate damage in muscular dystrophy.
Exercise preconditioning reduces neonatal incision surgery-induced enhanced hyperalgesia via inhibition of P38 mitogen-activated protein kinase and IL-1β, TNF-α release.
Low level of FOXL1 indicates a worse prognosis for gastric cancer patients.
Dynamic distributions of tumor necrosis factor-alpha and its receptors in the red nucleus of rats with spared nerve injury.
LINE-1 gene hypomethylation and p16 gene hypermethylation in HepG2 cells induced by low-dose and long-term triclosan exposure: The role of hydroxyl group.
Improvements of Glucose and Lipid Metabolism After Jejuno-ileal Circuit Procedure in a Non-obese Diabetic Rat Model.
NRAGE is involved in homologous recombination repair to resist the DNA-damaging chemotherapy and composes a ternary complex with RNF8-BARD1 to promote cell survival in squamous esophageal tumorigenesis.
Inhibition of the glucocorticoid receptor results in an enhanced miR-99a/100-mediated radiation response in stem-like cells from human prostate cancers.
Paper-based microreactor array for rapid screening of cell signaling cascades.
The long noncoding RNA ASNR regulates degradation of Bcl-2 mRNA through its interaction with AUF1.
Porcine reproductive and respiratory syndrome virus triggers mitochondrial fission and mitophagy to attenuate apoptosis.
Long non-coding RNA AFAP1-AS1 facilitates tumor growth and promotes metastasis in colorectal cancer.
EWSR1 regulates mitosis by dynamically influencing microtubule acetylation.
USP14 regulates autophagy by suppressing K63 ubiquitination of Beclin 1.
Constitutive translation of human α-synuclein is mediated by the 5'-untranslated region.
Upregulation of GSK3β Contributes to Brain Disorders in Elderly REGγ-knockout Mice.
Interplay of autophagy and apoptosis during PRRSV infection of Marc145 cell.
Down-regulation of ribosomal protein S15A inhibits proliferation of human glioblastoma cells in vivo and in vitro via AKT pathway.
Lead Inhibits Human Sperm Functions by Reducing the Levels of Intracellular Calcium, cAMP, and Tyrosine Phosphorylation.
Altered expression of miR-125a-5p in thymoma-associated myasthenia gravis and its down-regulation of foxp3 expression in Jurkat cells.
Lentivirus-mediated knockdown of CTDP1 inhibits lung cancer cell growth in vitro.
Downregulation of VEGF and upregulation of TL1A expression induce HUVEC apoptosis in response to high glucose stimuli.
β-Arrestins promote podocyte injury by inhibition of autophagy in diabetic nephropathy.
Linc-RoR promotes c-Myc expression through hnRNP I and AUF1.
Inhibition on Apoptosis Induced by Elevated Hydrostatic Pressure in Retinal Ganglion Cell-5 via Laminin Upregulating β1-integrin/Focal Adhesion Kinase/Protein Kinase B Signaling Pathway.
Autocrine Sonic hedgehog signaling promotes gastric cancer proliferation through induction of phospholipase Cγ1 and the ERK1/2 pathway.
A Point Mutation in the Exon Junction Complex Factor Y14 Disrupts Its Function in mRNA Cap Binding and Translation Enhancement.
Comparative proteomic study of the response to hypoxia in the muscle of oriental river prawn (Macrobrachium nipponense).
Forced cell cycle exit and modulation of GABAA, CREB, and GSK3β signaling promote functional maturation of induced pluripotent stem cell-derived neurons.
PACE4 regulates apoptosis in human prostate cancer cells via endoplasmic reticulum stress and mitochondrial signaling pathways.
Trefoil factor 1 elevates the malignant phenotype of mucinous ovarian cancer cell through Wnt/β-catenin signaling.
Complement factors C1q, C3 and C5b-9 in the posterior sclera of guinea pigs with negative lens-defocused myopia.
Regulative Effect of Nampt on Tumor Progression and Cell Viability in Human Colorectal Cancer.
Highly expressed UNC119 promotes hepatocellular carcinoma cell proliferation through Wnt/β-catenin signaling and predicts a poor prognosis.
Huaier Aqueous Extract Induces Hepatocellular Carcinoma Cells Arrest in S Phase via JNK Signaling Pathway.
A Selected Lactobacillus rhamnosus Strain Promotes EGFR-Independent Akt Activation in an Enterotoxigenic Escherichia coli K88-Infected IPEC-J2 Cell Model.
Down-Regulation of NDUFB9 Promotes Breast Cancer Cell Proliferation, Metastasis by Mediating Mitochondrial Metabolism.
Effects of Carbon Nanotube Environmental Dispersion on an Aquatic Invertebrate, Hirudo medicinalis.
CRISPR/Cas9 Promotes Functional Study of Testis Specific X-Linked Gene In Vivo.
Endothelial cell-targeted pVEGF165 polyplex plays a pivotal role in inhibiting intimal thickening after vascular injury.
Circulating microparticles from patients with valvular heart disease and cardiac surgery inhibit endothelium-dependent vasodilation.
Effect of Huaier on the proliferation and apoptosis of human gastric cancer cells through modulation of the PI3K/AKT signaling pathway.
Phase transition of spindle-associated protein regulate spindle apparatus assembly.
SUMOylation at K707 of DGCR8 controls direct function of primary microRNA.
Prosaposin facilitates sortilin-independent lysosomal trafficking of progranulin.
Identification of cellular microRNA-136 as a dual regulator of RIG-I-mediated innate immunity that antagonizes H5N1 IAV replication in A549 cells.
Protein kinase CK2α catalytic subunit is overexpressed and serves as an unfavorable prognostic marker in primary hepatocellular carcinoma.
FGF1-FGFR1 axis promotes tongue squamous cell carcinoma (TSCC) metastasis through epithelial-mesenchymal transition (EMT).
BPTF promotes tumor growth and predicts poor prognosis in lung adenocarcinomas.
Neuroleukin/Autocrine Motility Factor Receptor Pathway Promotes Proliferation of Articular Chondrocytes through Activation of AKT and Smad2/3.
RanGTP aids anaphase entry through Ubr5-mediated protein turnover.
FOXL2 down-regulates vitellogenin expression at mature stage in Eriocheir sinensis.
G-protein-coupled receptor 137 accelerates proliferation of urinary bladder cancer cells in vitro.
MiR542-3p Regulates the Epithelial-Mesenchymal Transition by Directly Targeting BMP7 in NRK52e.
Phosphorylation and activation of ubiquitin-specific protease-14 by Akt regulates the ubiquitin-proteasome system.
Encephalomyocarditis Virus 3C Protease Relieves TRAF Family Member-associated NF-κB Activator (TANK) Inhibitory Effect on TRAF6-mediated NF-κB Signaling through Cleavage of TANK.
Co-expression of mitosis-regulating genes contributes to malignant progression and prognosis in oligodendrogliomas.
Dental Abnormalities Caused by Novel Compound Heterozygous CTSK Mutations.
Vav3 oncogene is upregulated and a poor prognostic factor in breast cancer patients.
Microgravity activates p38 MAPK-C/EBPβ pathway to regulate the expression of arginase and inflammatory cytokines in macrophages.
Mitosis. Microtubule detyrosination guides chromosomes during mitosis.
Oxysophocarpine Ameliorates Carrageenan-induced Inflammatory Pain via Inhibiting Expressions of Prostaglandin E2 and Cytokines in Mice.
HAP1 helps to regulate actin-based transport of insulin-containing granules in pancreatic β cells.
Pigment epithelium-derived factor regulates microvascular permeability through adipose triglyceride lipase in sepsis.
MNRR1 (formerly CHCHD2) is a bi-organellar regulator of mitochondrial metabolism.
Proteomic profile in Perna viridis after exposed to Prorocentrum lima, a dinoflagellate producing DSP toxins.
DNA methylation downregulated mir-10b acts as a tumor suppressor in gastric cancer.
Toward operative in vivo fluorescence imaging of the c-Met proto-oncogene for personalization of therapy in ovarian cancer.
Lentivirus-mediated silencing of SCIN inhibits proliferation of human lung carcinoma cells.
Novel function of PITH domain-containing 1 as an activator of internal ribosomal entry site to enhance RUNX1 expression and promote megakaryocyte differentiation.
Annexin A3 as a potential target for immunotherapy of liver cancer stem-like cells.
Human mammary microenvironment better regulates the biology of human breast cancer in humanized mouse model.
Potent effects of the total saponins from Dioscorea nipponica Makino against streptozotocin-induced type 2 diabetes mellitus in rats.
Moesin and myosin phosphatase confine neutrophil orientation in a chemotactic gradient.
Targeting non-coding RNAs with the CRISPR/Cas9 system in human cell lines.
The Energy Metabolism in Caenorhabditis elegans under The Extremely Low-Frequency Electromagnetic Field Exposure.
Flavivirus Infection Impairs Peroxisome Biogenesis and Early Antiviral Signaling.
Erythropoietin Protects Retinal Cells in Diabetic Rats Through Upregulating ZnT8 via Activating ERK Pathway and Inhibiting HIF-1α Expression.
Tumor necrosis factor α induces myofibroblast differentiation in human tongue cancer and promotes invasiveness and angiogenesis via secretion of stromal cell-derived factor-1.
Protection of seven dibenzocyclooctadiene lignans from Schisandra chinensis against serum and glucose deprivation injury in SH-SY5Y cells.
Cancer-testis antigen MAGE-C2 binds Rbx1 and inhibits ubiquitin ligase-mediated turnover of cyclin E.
MicroRNA-186 induces sensitivity of ovarian cancer cells to paclitaxel and cisplatin by targeting ABCB1.
The Mediator subunit MED23 couples H2B mono-ubiquitination to transcriptional control and cell fate determination.
Involvement of AMPK/SIRT1 pathway in anti-allodynic effect of troxerutin in CCI-induced neuropathic pain.
miRNA-204 drives cardiomyocyte proliferation via targeting Jarid2.
Genipin inhibits NLRP3 and NLRC4 inflammasome activation via autophagy suppression.
Activation of AMPK restricts coxsackievirus B3 replication by inhibiting lipid accumulation.
CXCR1/2 antagonism with CXCL8/Interleukin-8 analogue CXCL8(3-72)K11R/G31P restricts lung cancer growth by inhibiting tumor cell proliferation and suppressing angiogenesis.
The Antiviral Effect of Baicalin on Enterovirus 71 In Vitro.
Cdc42-Interacting Protein 4 Represses E-Cadherin Expression by Promoting β-Catenin Translocation to the Nucleus in Murine Renal Tubular Epithelial Cells.
si-RNA-mediated knockdown of PDLIM5 suppresses gastric cancer cell proliferation in vitro.
DNA methylation regulates bromodomain-containing protein 2 expression during adipocyte differentiation.
Ppm1b negatively regulates necroptosis through dephosphorylating Rip3.
GSK3β-Dzip1-Rab8 cascade regulates ciliogenesis after mitosis.
MicroRNA‑133b inhibits connective tissue growth factor in colorectal cancer and correlates with the clinical stage of the disease.
Modification of BECN1 by ISG15 plays a crucial role in autophagy regulation by type I IFN/interferon.
The tumor suppressor role of miR-124 in osteosarcoma.
Megakaryocytic differentiation of K562 cells induced by PMA reduced the activity of respiratory chain complex IV.
MicroRNA-424 is down-regulated in hepatocellular carcinoma and suppresses cell migration and invasion through c-Myb.
The self-interaction of a nodavirus replicase is enhanced by mitochondrial membrane lipids.
Leptin downregulates aggrecan through the p38-ADAMST pathway in human nucleus pulposus cells.
MicroRNA-217 regulates WASF3 expression and suppresses tumor growth and metastasis in osteosarcoma.
MicroRNA-10a is down-regulated by DNA methylation and functions as a tumor suppressor in gastric cancer cells.
Sox9 regulates hyperexpression of Wnt1 and Fzd1 in human osteosarcoma tissues and cells.
Expression of leucine aminopeptidase 3 (LAP3) correlates with prognosis and malignant development of human hepatocellular carcinoma (HCC).
Cytohesin-3 is upregulated in hepatocellular carcinoma and contributes to tumor growth and vascular invasion.
SERPINA3 promotes endometrial cancer cells growth by regulating G2/M cell cycle checkpoint and apoptosis.
Gemcitabine resistance in breast cancer cells regulated by PI3K/AKT-mediated cellular proliferation exerts negative feedback via the MEK/MAPK and mTOR pathways.
Distinct Orai-coupling domains in STIM1 and STIM2 define the Orai-activating site.
Production of transgenic pigs over-expressing the antiviral gene Mx1.
Type 2 diabetes mellitus control and atherosclerosis prevention in a non-obese rat model using duodenal-jejunal bypass.
High density lipoprotein from patients with valvular heart disease uncouples endothelial nitric oxide synthase.
Neuroprotective effect of schizandrin A on oxygen and glucose deprivation/reperfusion-induced cell injury in primary culture of rat cortical neurons.
Altered expression of hypoxia-Inducible factor-1α participates in the epileptogenesis in animal models.
Regulation of silicosis formation by lysophosphatidic acid and its receptors.
MicroRNA-217 functions as a tumour suppressor gene and correlates with cell resistance to cisplatin in lung cancer.
Regulation of COX-2 expression by miR-146a in lung cancer cells.
SILAC-based quantitative proteomic analysis of secretome between activated and reverted hepatic stellate cells.
Dioscin attenuates hepatic ischemia-reperfusion injury in rats through inhibition of oxidative-nitrative stress, inflammation and apoptosis.
Hypoxia-inducible factor 1α mediates neuroprotection of hypoxic postconditioning against global cerebral ischemia.
Nardilysin-dependent proteolysis of cell-associated VTCN1 (B7-H4) marks type 1 diabetes development.
CKIP-1 suppresses the adipogenesis of mesenchymal stem cells by enhancing HDAC1-associated repression of C/EBPα.
Suppression of toll-like receptor 2 expression inhibits the bioactivity of human hepatocellular carcinoma.
PP242 synergizes with suberoylanilide hydroxamic acid to inhibit growth of ovarian cancer cells.
The involvement of CXCR7 in modulating the progression of papillary thyroid carcinoma.
Up-regulation of hexokinase1 in the right ventricle of monocrotaline induced pulmonary hypertension.
MicroRNA-188 suppresses G1/S transition by targeting multiple cyclin/CDK complexes.
Elevated autocrine EDIL3 protects hepatocellular carcinoma from anoikis through RGD-mediated integrin activation.
Down-regulation of asparagine synthetase induces cell cycle arrest and inhibits cell proliferation of breast cancer.
Rho/Rock cross-talks with transforming growth factor-β/Smad pathway participates in lung fibroblast-myofibroblast differentiation.
TBC1D9B functions as a GTPase-activating protein for Rab11a in polarized MDCK cells.
Effects of the total saponins from Rosa laevigata Michx fruit against acetaminophen-induced liver damage in mice via induction of autophagy and suppression of inflammation and apoptosis.
Nasopharyngeal cancer-specific therapy based on fusion peptide-functionalized lipid nanoparticles.
Effect of nigranoic acid on Ca²⁺ influx and its downstream signal mechanism in NGF-differentiated PC12 cells.
Molecular characterization and expression analysis of the autophagic gene beclin 1 from the purse red common carp (Cyprinus carpio) exposed to cadmium.
miR-21 promotes human nucleus pulposus cell proliferation through PTEN/AKT signaling.
Novel function of the chromosome 7 open reading frame 41 gene to promote leukemic megakaryocyte differentiation by modulating TPA-induced signaling.
Molecular analysis of curcumin-induced polarization of murine RAW264.7 macrophages.
The roles of p38 MAPK/MSK1 signaling pathway in the neuroprotection of hypoxic postconditioning against transient global cerebral ischemia in adult rats.
MGARP regulates mouse neocortical development via mitochondrial positioning.
HepaCAM inhibits clear cell renal carcinoma 786-0 cell proliferation via blocking PKCε translocation from cytoplasm to plasma membrane.
p16 Methylation is associated with chemosensitivity to fluorouracil in patients with advanced gastric cancer.
Negative association of R-Ras activation and breast cancer development.
Toxoplasma gondii inhibits apoptosis via a novel STAT3-miR-17-92-Bim pathway in macrophages.
Activation of JNK1/2 and p38 MAPK signaling pathways promotes enterovirus 71 infection in immature dendritic cells.
Oxidored-nitro domain containing protein 1 (NOR1) expression suppresses slug/vimentin but not snail in nasopharyngeal carcinoma: Inhibition of EMT in vitro and in vivo in mice.
KIF2A silencing inhibits the proliferation and migration of breast cancer cells and correlates with unfavorable prognosis in breast cancer.
Mulberroside A protects against ischemic impairment in primary culture of rat cortical neurons after oxygen-glucose deprivation followed by reperfusion.
LPS induced miR-181a promotes pancreatic cancer cell migration via targeting PTEN and MAP2K4.
Regulated intramembrane proteolysis of the frontotemporal lobar degeneration risk factor, TMEM106B, by signal peptide peptidase-like 2a (SPPL2a).
The inhibitory effect of IFN-γ on protease HTRA1 expression in rheumatoid arthritis.
Neuroprotection by (-)-epigallocatechin-3-gallate in a rat model of stroke is mediated through inhibition of endoplasmic reticulum stress.
Microgravity inhibition of lipopolysaccharide-induced tumor necrosis factor-α expression in macrophage cells.
iTRAQ-based proteomic analysis of dioscin on human HCT-116 colon cancer cells.
Dengue virus subgenomic RNA induces apoptosis through the Bcl-2-mediated PI3k/Akt signaling pathway.
Long non-coding RNA UCA1 promotes breast tumor growth by suppression of p27 (Kip1).
High glucose induces activation of the local renin‑angiotensin system in glomerular endothelial cells.
Pretreatment of mice with oligonucleotide prop5 protects them from influenza virus infections.
Akt/Ezrin Tyr353/NF-κB pathway regulates EGF-induced EMT and metastasis in tongue squamous cell carcinoma.
A microtubule-associated zinc finger protein, BuGZ, regulates mitotic chromosome alignment by ensuring Bub3 stability and kinetochore targeting.
An alternative splicing isoform of MITA antagonizes MITA-mediated induction of type I IFNs.
Protein profiling the differences between diabetic and normal mouse cumulus cells.
Levofloxacin increases the effect of serum deprivation on anoikis of rat nucleus pulposus cells via Bax/Bcl-2/caspase-3 pathway.
Differential effects of agonistic 4-1BB (CD137) monoclonal antibody on the maturation and functions of hypoxic dendritic cells.
Effects of sodium fluoride treatment in vitro on cell proliferation, BMP-2 and BMP-3 expression in human osteosarcoma MG-63 cells.
A recessive variant of XRCC4 predisposes to non- BRCA1/2 breast cancer in chinese women and impairs the DNA damage response via dysregulated nuclear localization.
Calreticulin promotes migration and invasion of esophageal cancer cells by upregulating neuropilin-1 expression via STAT5A.
Decreased expression of TRIM3 is associated with poor prognosis in patients with primary hepatocellular carcinoma.
Potent effects of flavonoid-rich extract from Rosa laevigata Michx fruit against hydrogen peroxide-induced damage in PC12 cells via attenuation of oxidative stress, inflammation and apoptosis.
microRNA 490-3P enhances the drug-resistance of human ovarian cancer cells.
DNA methylation-mediated silencing of matricellular protein dermatopontin promotes hepatocellular carcinoma metastasis by α3β1 integrin-Rho GTPase signaling.
Oxidoreductase activity is necessary for N-glycosylation of cysteine-proximal acceptor sites in glycoproteins.
Puerarin protected the brain from cerebral ischemia injury via astrocyte apoptosis inhibition.
The role of SIRT6 in the differentiation of vascular smooth muscle cells in response to cyclic strain.
A synergic role of caspase-6 and caspase-3 in Tau truncation at D421 induced by H2O 2.
Protective effects of the total saponins from Dioscorea nipponica Makino against carbon tetrachloride-induced liver injury in mice through suppression of apoptosis and inflammation.
Sine oculis homeobox homolog 1 promotes α5β1-mediated invasive migration and metastasis of cervical cancer cells.
Umbilical cord blood cells regulate the differentiation of endogenous neural stem cells in hypoxic ischemic neonatal rats via the hedgehog signaling pathway.
IKKα restoration via EZH2 suppression induces nasopharyngeal carcinoma differentiation.
Cadmium induces liver cell apoptosis through caspase-3A activation in purse red common carp (Cyprinus carpio).
MicroRNA-10b promotes nucleus pulposus cell proliferation through RhoC-Akt pathway by targeting HOXD10 in intervetebral disc degeneration.
Simvastatin alleviates hyperpermeability of glomerular endothelial cells in early-stage diabetic nephropathy by inhibition of RhoA/ROCK1.
Identification of three antiviral inhibitors against Japanese encephalitis virus from library of pharmacologically active compounds 1280.
Resolvin D1 reverts lipopolysaccharide-induced TJ proteins disruption and the increase of cellular permeability by regulating IκBα signaling in human vascular endothelial cells.
Anti-miRNA-23a oligonucleotide suppresses glioma cells growth by targeting apoptotic protease activating factor-1.
Proteomic studies of multiple myeloma in RPMI8226 cell line treated with bendamustine.
Differential roles of C-terminal Eps15 homology domain proteins as vesiculators and tubulators of recycling endosomes.
Molecular cloning, immunohistochemical localization, characterization and expression analysis of caspase-9 from the purse red common carp (Cyprinus carpio) exposed to cadmium.
Lipopolysaccharide increases the incidence of collagen-induced arthritis in mice through induction of protease HTRA-1 expression.
Effects of perchlorate on BDE-47-induced alteration thyroid hormone and gene expression of in the hypothalamus-pituitary-thyroid axis in zebrafish larvae.
MicroRNA-124 mediates the cholinergic anti-inflammatory action through inhibiting the production of pro-inflammatory cytokines.
Synergistic anti-glioma effect of Hydroxygenkwanin and Apigenin in vitro.
Amyloid-β(1-42) oligomer accelerates senescence in adult hippocampal neural stem/progenitor cells via formylpeptide receptor 2.
Fructose-1,6-bisphosphatase, Malate Dehydrogenase, Isocitrate Lyase, Phosphoenolpyruvate Carboxykinase, Glyceraldehyde-3-phosphate Dehydrogenase, and Cyclophilin A are secreted in Saccharomyces cerevisiae grown in low glucose.
Protection of the flavonoid fraction from Rosa laevigata Michx fruit against carbon tetrachloride-induced acute liver injury in mice.
PPE38 of Mycobacterium marinum triggers the cross-talk of multiple pathways involved in the host response, as revealed by subcellular quantitative proteomics.
Inositol-requiring protein 1α signaling pathway is activated in the temporal cortex of patients with mesial temporal lobe epilepsy.
Salidroside protects against hydrogen peroxide-induced injury in HUVECs via the regulation of REDD1 and mTOR activation.
c-Src regulates cell cycle proteins expression through protein kinase B/glycogen synthase kinase 3 beta and extracellular signal-regulated kinases 1/2 pathways in MCF-7 cells.
Identification of STAT2 serine 287 as a novel regulatory phosphorylation site in type I interferon-induced cellular responses.
INMAP, a novel truncated version of POLR3B, represses AP-1 and p53 transcriptional activity.
Hyperforin attenuates brain damage induced by transient middle cerebral artery occlusion (MCAO) in rats via inhibition of TRPC6 channels degradation.
PES1 regulates sensitivity of colorectal cancer cells to anticancer drugs.
Neuroprotective effect of calcitriol on ischemic/reperfusion injury through the NR3A/CREB pathways in the rat hippocampus.
Isoquercetin protects cortical neurons from oxygen-glucose deprivation-reperfusion induced injury via suppression of TLR4-NF-кB signal pathway.
Cadmium triggers kidney cell apoptosis of purse red common carp (Cyprinus carpio) without caspase-8 activation.
STAT3-dependent transactivation of miRNA genes following Toxoplasma gondii infection in macrophage.
miR-133b, a muscle-specific microRNA, is a novel prognostic marker that participates in the progression of human colorectal cancer via regulation of CXCR4 expression.
Effects of flavonoids from Rosa laevigata Michx fruit against high-fat diet-induced non-alcoholic fatty liver disease in rats.
Neuroprotectin D1 attenuates brain damage induced by transient middle cerebral artery occlusion in rats through TRPC6/CREB pathways.
Induction of apoptosis in infantile hemangioma endothelial cells by propranolol.
Lumbrokinase attenuates diabetic nephropathy through regulating extracellular matrix degradation in Streptozotocin-induced diabetic rats.
Vps34p is required for the decline of extracellular fructose-1,6-bisphosphatase in the vacuole import and degradation pathway.
The p16-specific reactivation and inhibition of cell migration through demethylation of CpG islands by engineered transcription factors.
Phosphatase of regenerating liver-3 directly interacts with integrin β1 and regulates its phosphorylation at tyrosine 783.
miR-129-3p controls cilia assembly by regulating CP110 and actin dynamics.
Embryonic liver fodrin involved in hepatic stellate cell activation and formation of regenerative nodule in liver cirrhosis.
A novel mouse model of gastric cancer with human gastric microenvironment.
β-2 spectrin is involved in hepatocyte proliferation through the interaction of TGFβ/Smad and PI3K/AKT signalling.
Genetic and epigenetic control of UNC5C expression in human renal cell carcinoma.
SCFFBXL¹⁵ regulates BMP signalling by directing the degradation of HECT-type ubiquitin ligase Smurf1.
Transplanted olfactory ensheathing cells reduce the gliotic injury response of Müller cells in a rat model of retinitis pigmentosa.
Differentiation of human bone marrow mesenchymal stem cells into neuron-like cells in vitro.
Fabp3 inhibits proliferation and promotes apoptosis of embryonic myocardial cells.
Differential expression of microRNAs in cardiac myocytes compared to undifferentiated P19 cells.
Involvement of IRE1α signaling in the hippocampus in patients with mesial temporal lobe epilepsy.
Differential proteome analysis of bone marrow mesenchymal stem cells from adolescent idiopathic scoliosis patients.
Functional characterization of inward rectifier potassium ion channel in murine fetal ventricular cardiomyocytes.
Alpha1,3 fucosyltransferase VII plays a role in colorectal carcinoma metastases by promoting the carbohydration of glycoprotein CD24.
Inhibition of epithelial to mesenchymal transition in metastatic breast carcinoma cells by c-Src suppression.
The role of enoyl-CoA hydratase short chain 1 and peroxiredoxin 3 in PP2-induced apoptosis in human breast cancer MCF-7 cells.
SZ-685C, a marine anthraquinone, is a potent inducer of apoptosis with anticancer activity by suppression of the Akt/FOXO pathway.
Epidermal growth factor stimulates human trophoblast cell migration through Rho A and Rho C activation.
Electrophysiological study on differentiation of rat bone marrow stromal stem cells into neuron-like cells in vitro by edaravone.
Palladin is overexpressed in the non-neoplastic stroma of infiltrating ductal adenocarcinomas of the pancreas, but is only rarely overexpressed in neoplastic cells.
Wang S, Li H, Liu Q, Ma H, Huang L, Yu L, Wu Z
International heart journal 2024;65(2):318-328
International heart journal 2024;65(2):318-328
In vitro and in vivo studies on the effect of a mitochondrial fusion promoter on Leydig cell integrity and function.
Garza S, Sottas C, Gukasyan HJ, Papadopoulos V
Frontiers in toxicology 2024;6:1357857
Frontiers in toxicology 2024;6:1357857
Deactivation of the Unfolded Protein Response Aggravated Renal AA Amyloidosis in HSF1 Deficiency Mice.
Liu W, Xia S, Yao F, Huo J, Qian J, Liu X, Bai L, Song Y, Qian J
Molecular and cellular biology 2024;44(5):165-177
Molecular and cellular biology 2024;44(5):165-177
GPX4 inhibits apoptosis of thyroid cancer cells through regulating the FKBP8/Bcl-2 axis.
Dang T, Yu J, Yu Y, Jiang J, Shi Y, Yu S, Peng C, Min X, Xiong Y, Long P, Zhou W, Dai D
Cancer biomarkers : section A of Disease markers 2024;39(4):349-360
Cancer biomarkers : section A of Disease markers 2024;39(4):349-360
Proximity Mapping of Ciliary Proteins by BioID.
Iazzi M, St-Germain J, Acharya S, Raught B, Gupta GD
Methods in molecular biology (Clifton, N.J.) 2024;2725:181-198
Methods in molecular biology (Clifton, N.J.) 2024;2725:181-198
Therapeutic potential of HUC-MSC-exos primed with IFN-γ against LPS-induced acute lung injury.
Wang C, Jiang C, Yang Y, Xi C, Yin Y, Wu H, Qian C
Iranian journal of basic medical sciences 2024;27(3):375-382
Iranian journal of basic medical sciences 2024;27(3):375-382
Ovarian ferroptosis induced by androgen is involved in pathogenesis of PCOS.
Li X, Lin Y, Cheng X, Yao G, Yao J, Hu S, Zhu Q, Wang Y, Ding Y, Lu Y, Qi J, Zhao H, Bian X, Du Y, Sun K, Vankelecom H, Sun Y
Human reproduction open 2024;2024(2):hoae013
Human reproduction open 2024;2024(2):hoae013
Huaju Xiaoji Formula Regulates ERS-lncMGC/miRNA to Enhance the Renal Function of Hypertensive Diabetic Mice with Nephropathy.
Zhang Z, Fu X, Zhou F, Zhang D, Xu Y, Fan Z, Wen S, Shao Y, Yao Z, He Y
Journal of diabetes research 2024;2024:6942156
Journal of diabetes research 2024;2024:6942156
WTAP Mediated N6-methyladenosine RNA Modification of ELF3 Drives Cellular Senescence by Upregulating IRF8.
Zhou L, Zhong Y, Wang F, Guo Y, Mao R, Xie H, Zhang Y, Li J
International journal of biological sciences 2024;20(5):1763-1777
International journal of biological sciences 2024;20(5):1763-1777
PARP1 Promotes Heart Regeneration and Cardiomyocyte Proliferation.
Shu J, Yan S, Ju C, Chen L, Liang M, Wang C, Huang K
International journal of biological sciences 2024;20(5):1602-1616
International journal of biological sciences 2024;20(5):1602-1616
Lysozyme promotes renal fibrosis through the JAK/STAT3 signal pathway in diabetic nephropathy.
Ren Y, Yu M, Zheng D, He W, Jin J
Archives of medical science : AMS 2024;20(1):233-247
Archives of medical science : AMS 2024;20(1):233-247
Pan-cancer analysis of PSCA that is associated with immune infiltration and affects patient prognosis.
Wang C, Zhu X, Zheng M, Chen Y, Jiang R, He X, Liu Z, Lu Z, Wang Z, Yang Y
PloS one 2024;19(6):e0298469
PloS one 2024;19(6):e0298469
Echinatin attenuates acute lung injury and inflammatory responses via TAK1-MAPK/NF-κB and Keap1-Nrf2-HO-1 signaling pathways in macrophages.
Luo L, Wang H, Xiong J, Chen X, Shen X, Zhang H
PloS one 2024;19(5):e0303556
PloS one 2024;19(5):e0303556
Rauwolfia polysaccharide can inhibit the progress of ulcerative colitis through NOS2-mediated JAK2/STAT3 pathway.
Wu H, Jiang F, Yuan W, Zhao Y, Liu N, Miao X
PloS one 2024;19(4):e0301660
PloS one 2024;19(4):e0301660
circTADA2A inhibited SLC38A1 expression and suppresses melanoma progression through the prevention of CNBP trans-activation.
Zhang L, Zhang L, Zhang C, Shi S, Cao Z, Shao C, Li J, Yang Y, Zhang X, Wang J, Li X
PloS one 2024;19(4):e0301356
PloS one 2024;19(4):e0301356
Functional analysis of ESM1 by shRNA-mediated knockdown of its expression in papillary thyroid cancer cells.
Xie L, He L, Zhang W, Wang H
PloS one 2024;19(4):e0298631
PloS one 2024;19(4):e0298631
FBLN5 was Regulated by PRDM9, and Promoted Senescence and Osteogenic Differentiation of Human Periodontal Ligament Stem Cells.
Zhao M, Rong R, Zhang C, Yang H, Han X, Fan Z, Zheng Y, Zhang J
Current stem cell research & therapy 2024;19(3):417-425
Current stem cell research & therapy 2024;19(3):417-425
Downregulation of the CD151 protects the cardiac function by the crosstalk between the endothelial cells and cardiomyocytes via exosomes.
Jiang L, Liu J, Yang Z, Wang J, Ke W, Zhang K, Zhang C, Zuo H
PloS one 2024;19(2):e0297121
PloS one 2024;19(2):e0297121
METTL3-mediated methylation of CYP2C19 mRNA may aggravate clopidogrel resistance in ischemic stroke patients.
Tan Q, Yang L, Yuan S, Zheng D, Lin Y, Chen K, He Y, Chen S, Hao J, Dai J, He S, Mao F, Leng X, Jiang H, Yang J
Open medicine (Warsaw, Poland) 2024;19(1):20240899
Open medicine (Warsaw, Poland) 2024;19(1):20240899
KAT2A changes the function of endometrial stromal cells via regulating the succinylation of ENO1.
Zeng K, Yin H
Open life sciences 2024;19(1):20220785
Open life sciences 2024;19(1):20220785
Silencing KLF6 Alleviates Cigarette Smoke Extract-Induced Mitochondrial Dysfunction in Bronchial Epithelial Cells by SIRT4 Upregulation.
Wan M, Wang C, Cui J, Xia Q, Zhang L
International journal of chronic obstructive pulmonary disease 2024;19:815-828
International journal of chronic obstructive pulmonary disease 2024;19:815-828
Lipid-Based Self-Microemulsion of Niclosamide Achieved Enhanced Oral Delivery and Anti-Tumor Efficacy in Orthotopic Patient-Derived Xenograft of Hepatocellular Carcinoma in Mice.
Liu Y, Guerrero DQ, Lechuga-Ballesteros D, Tan M, Ahmad F, Aleiwi B, Ellsworth EL, Chen B, Chua MS, So S
International journal of nanomedicine 2024;19:2639-2653
International journal of nanomedicine 2024;19:2639-2653
A convenient model of serum-induced reactivity of human astrocytes to investigate astrocyte-derived extracellular vesicles.
White KE, Bailey HL, Shaw BS, Geiszler PC, Mesquita-Ribeiro R, Scott D, Layfield R, Serres S
Frontiers in cellular neuroscience 2024;18:1414142
Frontiers in cellular neuroscience 2024;18:1414142
Huang Gan Formula Alleviates Systemic Inflammation and Uremia in Adenine-Induced Chronic Kidney Disease Rats May Associate with Modification of Gut Microbiota and Colonic Microenvironment.
Zhao J, Zhao C, Xun T, Wang X, Wei S, Ye C, Zhang M, Guo D, Yang X
Drug design, development and therapy 2024;18:13-28
Drug design, development and therapy 2024;18:13-28
Identification of Transcriptomic Signatures of Pancreatic Ductal Adenocarcinoma-Derived Exosomes That Promote Macrophage M2 Polarization and Predict Prognosis: S100A9 Reveals Tumor Progression.
Tan S, Tang H, Zhang Z, Wang Y, Li H, Shi W, Ye H, Xie P, Zhou J
Clinical Medicine Insights. Oncology 2024;18:11795549241239042
Clinical Medicine Insights. Oncology 2024;18:11795549241239042
Trimethylamine N-oxide aggravates vascular permeability and endothelial cell dysfunction under diabetic condition: in vitro and in vivo study.
Jiang JY, Liu WM, Zhang QP, Ren H, Yao QY, Liu GQ, Lu PR
International journal of ophthalmology 2024;17(1):25-33
International journal of ophthalmology 2024;17(1):25-33
Comprehensive Analysis of Fatty Acid Metabolism in Diabetic Nephropathy from the Perspective of Immune Landscapes, Diagnosis and Precise Therapy.
Zhu E, Zhong M, Liang T, Liu Y, Wu K, Zhang Z, Zhao S, Guan H, Chen J, Zhang LZ, Zhang Y
Journal of inflammation research 2024;17:693-710
Journal of inflammation research 2024;17:693-710
Progerin Inhibits the Proliferation and Migration of Melanoma Cells by Regulating the Expression of Paxillin.
Liu W, Huang X, Luo W, Liu X, Chen W
OncoTargets and therapy 2024;17:227-242
OncoTargets and therapy 2024;17:227-242
NAD-Dependent Protein Deacetylase Sirtuin-1 Mediated Mitophagy Regulates Early Brain Injury After Subarachnoid Hemorrhage.
Wang G, Lin N
Journal of inflammation research 2024;17:1971-1981
Journal of inflammation research 2024;17:1971-1981
Consequences of GMPPB deficiency for neuromuscular development and maintenance.
Schurig MK, Umeh O, Henze H, Jung MJ, Gresing L, Blanchard V, von Maltzahn J, Hübner CA, Franzka P
Frontiers in molecular neuroscience 2024;17:1356326
Frontiers in molecular neuroscience 2024;17:1356326
Prognostic value of RNF113A shows a correlation with immune infiltrates in colorectal cancer.
Chen M, Song X, Lin H, Cheng W
American journal of translational research 2024;16(4):1281-1294
American journal of translational research 2024;16(4):1281-1294
ASB6 as an Independent Prognostic Biomarker for Colorectal Cancer Progression Involves Lymphatic Invasion and Immune Infiltration.
Hu Q, Chen Y, Zhou Q, Deng S, Mu B, Tang J
Journal of Cancer 2024;15(9):2712-2730
Journal of Cancer 2024;15(9):2712-2730
KRT80 Promotes Lung Adenocarcinoma Progression and Serves as a Substrate for VCP.
Huang S, Tong W, Yang B, Ma L, Zhang J, Wang C, Xu L, Mei J
Journal of Cancer 2024;15(8):2229-2244
Journal of Cancer 2024;15(8):2229-2244
FEN1 Promotes Hepatocellular Carcinoma Progression by Activating Cell Cycle Transition from G2 To M Phase.
Wang R, Zhang H, Huang D, Xu J, Zhang Y, Wang T
Journal of Cancer 2024;15(4):981-989
Journal of Cancer 2024;15(4):981-989
Berberine-mediated Ferroptosis through System Xc(-)/GSH/GPX4 Axis Inhibits Metastasis of Nasopharyngeal Carcinoma.
Wu Y, Jia Q, Tang Q, Deng H, He Y, Tang F
Journal of Cancer 2024;15(3):685-698
Journal of Cancer 2024;15(3):685-698
HSPB8 Facilitates the Oncogenesis and Advancement of Bladder Cancer via Activation of HSP27.
Du W, Guo K, Wang P, Zhong J, Jiang N
Journal of Cancer 2024;15(3):645-658
Journal of Cancer 2024;15(3):645-658
IGFBP5, as a Prognostic Indicator Promotes Tumor Progression and Correlates with Immune Microenvironment in Glioma.
Lin J, Huang G, Zeng Q, Zhang R, Lin Y, Li Y, Huang B, Pan H
Journal of Cancer 2024;15(1):232-250
Journal of Cancer 2024;15(1):232-250
Polygonatum cyrtonema polysaccharides reshape the gut microbiota to ameliorate dextran sodium sulfate-induced ulcerative colitis in mice.
Lin C, Song D, Wang S, Chu Y, Chi C, Jia S, Lin M, He C, Jiang C, Gong F, Chen Q
Frontiers in pharmacology 2024;15:1424328
Frontiers in pharmacology 2024;15:1424328
Inhibition of NNMT enhances drug sensitivity in lung cancer cells through mediation of autophagy.
Wang J, Zhang M, You X, Xu Y, Zhang C, Li Y, Yang C, Wang Q
Frontiers in pharmacology 2024;15:1415310
Frontiers in pharmacology 2024;15:1415310
Identification of host proteins interacting with the E protein of porcine epidemic diarrhea virus.
Qiu Y, Sun Y, Zheng X, Gong L, Yang L, Xiang B
Frontiers in microbiology 2024;15:1380578
Frontiers in microbiology 2024;15:1380578
Research on the metabolic regulation mechanism of Yangyin Qingfei decoction plus in severe pneumonia caused by Mycoplasma pneumoniae in mice.
Zhang T, Zhao X, Zhang X, Liang X, Guan Z, Wang G, Liu G, Wu Z
Frontiers in pharmacology 2024;15:1376812
Frontiers in pharmacology 2024;15:1376812
PCBP1 interacts with the HTLV-1 Tax oncoprotein to potentiate NF-κB activation.
Su R, Kang X, Niu Y, Zhao T, Wang H
Frontiers in immunology 2024;15:1375168
Frontiers in immunology 2024;15:1375168
Inhibition of ACOX1 enhances the therapeutic efficacy of obeticholic acid in treating non-alcoholic fatty liver disease and mitigates its lipotoxicity.
Yang Y, Yuan W, He K, Lin C, Du S, Kou Y, Nie B
Frontiers in pharmacology 2024;15:1366479
Frontiers in pharmacology 2024;15:1366479
Identification of potential anti-inflammatory components in Moutan Cortex by bio-affinity ultrafiltration coupled with ultra-performance liquid chromatography mass spectrometry.
Zou C, Chen Q, Li J, Lin X, Xue X, Cai X, Chen Y, Sun Y, Wang S, Zhang Y, Meng J
Frontiers in pharmacology 2024;15:1358640
Frontiers in pharmacology 2024;15:1358640
Identification of potential novel N6-methyladenosine effector-related lncRNA biomarkers for serous ovarian carcinoma: a machine learning-based exploration in the framework of 3P medicine.
Ye L, Tong X, Pan K, Shi X, Xu B, Yao X, Zhuo L, Fang S, Tang S, Jiang Z, Xue X, Lu W, Guo G
Frontiers in pharmacology 2024;15:1351929
Frontiers in pharmacology 2024;15:1351929
Differences in F pocket impact on HLA I genetic associations with autoimmune diabetes.
Ren X, Amarajeewa AWP, Jayasinghe MDT, Garstka MA
Frontiers in immunology 2024;15:1342335
Frontiers in immunology 2024;15:1342335
Delineation of renal protein profiles in aristolochic acid I-induced nephrotoxicity in mice by label-free quantitative proteomics.
Liu X, Wu S, Peng Y, Gao L, Huang X, Deng R, Lu J
Frontiers in pharmacology 2024;15:1341854
Frontiers in pharmacology 2024;15:1341854
Genistein is effective in inhibiting Orf virus infection in vitro by targeting viral RNA polymerase subunit RPO30 protein.
Lv P, Fang Z, Guan J, Lv L, Xu M, Liu X, Li Z, Lan Y, Li Z, Lu H, Song D, He W, Gao F, Wang D, Zhao K
Frontiers in microbiology 2024;15:1336490
Frontiers in microbiology 2024;15:1336490
Transcriptome-wide 1-methyladenosine functional profiling of messenger RNA and long non-coding RNA in bladder cancer.
Yin JJ, Song YL, Guo YF, Dai YH, Chang Q, Wang T, Sun GQ, Lu P, Song DK, Zhang LR
Frontiers in genetics 2024;15:1333931
Frontiers in genetics 2024;15:1333931
Exosomal miR-223-3p from bone marrow mesenchymal stem cells targets HDAC2 to downregulate STAT3 phosphorylation to alleviate HBx-induced ferroptosis in podocytes.
Chen Y, Yang X, Feng M, Yu Y, Hu Y, Jiang W
Frontiers in pharmacology 2024;15:1327149
Frontiers in pharmacology 2024;15:1327149
USP50 regulates NLRP3 inflammasome activation in duodenogastric reflux-induced gastric tumorigenesis.
Zhao C, Mu M, Li X, Dong Z, Wang J, Yao C, Zheng J, Sun X, Yu J
Frontiers in immunology 2024;15:1326137
Frontiers in immunology 2024;15:1326137
Identification and validation of UBE2B as a prognostic biomarker promoting the development of esophageal carcinomas.
Ding H, Xu JC, Ding ZG, Wu LF, Liu YB, Zhang YF, Chen TY, Zhang YQ, Zhou PH
Frontiers in immunology 2024;15:1295305
Frontiers in immunology 2024;15:1295305
FSH induces EMT in ovarian cancer via ALKBH5-regulated Snail m6A demethylation.
Xu X, Zhuang X, Yu H, Li P, Li X, Lin H, Teoh JP, Chen Y, Yang Y, Cheng Y, Chen W, Fu X
Theranostics 2024;14(5):2151-2166
Theranostics 2024;14(5):2151-2166
Cancer-associated fibroblasts reprogram cysteine metabolism to increase tumor resistance to ferroptosis in pancreatic cancer.
Zhu Y, Fang S, Fan B, Xu K, Xu L, Wang L, Zhu L, Chen C, Wu R, Ni J, Wang J
Theranostics 2024;14(4):1683-1700
Theranostics 2024;14(4):1683-1700
SGK3 promotes vascular calcification via Pit-1 in chronic kidney disease.
Dong QQ, Tu YC, Gao P, Liao QQ, Zhou P, Zhang H, Shu HP, Sun LL, Feng L, Yao LJ
Theranostics 2024;14(2):861-878
Theranostics 2024;14(2):861-878
YY1-induced lncRNA00511 promotes melanoma progression via the miR-150-5p/ADAM19 axis.
Chen YN, Fu XR, Guo H, Fu XY, Shi KS, Gao T, Yu HQ
American journal of cancer research 2024;14(2):809-831
American journal of cancer research 2024;14(2):809-831
NRF2 promotes radiation resistance by cooperating with TOPBP1 to activate the ATR-CHK1 signaling pathway.
Sun X, Dong M, Li J, Sun Y, Gao Y, Wang Y, Du L, Liu Y, Ji K, He N, Wang J, Zhang M, Song H, Xu C, Liu Q
Theranostics 2024;14(2):681-698
Theranostics 2024;14(2):681-698
Arsenic trioxide suppresses lung adenocarcinoma stem cell stemness by inhibiting m6A modification to promote ferroptosis.
Jin W, Sun Y, Wang J, Wang Y, Chen D, Fang M, He J, Zhong L, Ren H, Zhang Y, Yin H, Wu S, Chen R, Yan W
American journal of cancer research 2024;14(2):507-525
American journal of cancer research 2024;14(2):507-525
Comprehensive analysis of peroxisome proliferator-activated receptors to predict the drug resistance, immune microenvironment, and prognosis in stomach adenocarcinomas.
Jia Q, Li B, Wang X, Ma Y, Li G
PeerJ 2024;12:e17082
PeerJ 2024;12:e17082
Low-intensity pulsed ultrasound promotes the osteogenesis of mechanical force-treated periodontal ligament cells via Piezo1.
Zheng F, Wu T, Wang F, Li H, Tang H, Cui X, Li C, Wang Y, Jiang J
Frontiers in bioengineering and biotechnology 2024;12:1347406
Frontiers in bioengineering and biotechnology 2024;12:1347406
Exercise attenuates high-fat diet-induced PVAT dysfunction through improved inflammatory response and BMP4-regulated adipose tissue browning.
Liu X, Jiang X, Hu J, Ding M, Lee SK, Korivi M, Qian Y, Li T, Wang L, Li W
Frontiers in nutrition 2024;11:1393343
Frontiers in nutrition 2024;11:1393343
Bioinformatics analysis and experimental verification of TIGD1 in non-small cell lung cancer.
Xia L, Yang Z, Xv M, Wang G, Mao Y, Yang Y, Tang J
Frontiers in medicine 2024;11:1374260
Frontiers in medicine 2024;11:1374260
Small extracellular vesicles from irradiated lung epithelial cells promote the activation of fibroblasts in pulmonary fibrosis.
Li N, Li K, Zhao W, Wang Y, Xu C, Wang Q, Pan L, Li Q, Ji K, He N, Liu Y, Wang J, Zhang M, Yang M, Du L, Liu Q
International journal of radiation biology 2024;100(2):268-280
International journal of radiation biology 2024;100(2):268-280
PIEZO1 mechanically regulates the antitumour cytotoxicity of T lymphocytes.
Pang R, Sun W, Yang Y, Wen D, Lin F, Wang D, Li K, Zhang N, Liang J, Xiong C, Liu Y
Nature biomedical engineering 2024 Sep;8(9):1162-1176
Nature biomedical engineering 2024 Sep;8(9):1162-1176
Identification of TUBB2A as a Cancer-Immunity Cycle-Related Therapeutic Target in Triple-Negative Breast Cancer.
Li J, Yao J, Qi L
Molecular biotechnology 2024 Sep;66(9):2467-2480
Molecular biotechnology 2024 Sep;66(9):2467-2480
CircPRRC2C Promotes the Oncogenic Phenotypes of Laryngeal Squamous Cell Carcinoma Cells via MiR-136-5p/HOXD11 Axis.
Peng X, Chen X, Peng S, Chen Y, Li Y, Tian Y
Molecular biotechnology 2024 Sep;66(9):2381-2395
Molecular biotechnology 2024 Sep;66(9):2381-2395
Quercetin Ameliorates Cognitive Impairment in Depression by Targeting HSP90 to Inhibit NLRP3 Inflammasome Activation.
Du L, Fan X, Yang Y, Wu S, Liu Y
Molecular neurobiology 2024 Sep;61(9):6628-6641
Molecular neurobiology 2024 Sep;61(9):6628-6641
Enhancing Fat Transplantation Efficiency in a Mouse Model through Pretreatment of Adipose-Derived Stem Cells with RIP3 Inhibitors.
Yang Z, Lu H, Gao Q, Yuan X, Hu Y, Qi Z
Aesthetic plastic surgery 2024 Sep;48(17):3488-3499
Aesthetic plastic surgery 2024 Sep;48(17):3488-3499
Locationally activated PRP via an injectable dual-network hydrogel for endometrial regeneration.
Qi J, Li X, Cao Y, Long Y, Lai J, Yao Y, Meng Y, Wang Y, Chen XD, Vankelecom H, Bian X, Cui W, Sun Y
Biomaterials 2024 Sep;309:122615
Biomaterials 2024 Sep;309:122615
Counteracting TGM2 by a Fibroin peptide ameliorated Adriamycin-induced nephropathy via regulation of lipid metabolism through PANX1-PPAR α/PANK1 pathway.
Li SS, Liu QJ, Bao JX, Lu MT, Deng BQ, Li WW, Cao CC
Translational research : the journal of laboratory and clinical medicine 2024 Sep;271:26-39
Translational research : the journal of laboratory and clinical medicine 2024 Sep;271:26-39
CTSD upregulation as a key driver of spinal ligament abnormalities in spinal stenosis.
Li L, Zheng ZZ, Jiang JJ, Chen JL, Jiang B, Li YW, Dai YL, Wang B
Bone 2024 Sep;186:117174
Bone 2024 Sep;186:117174
Naringenin relieves paclitaxel-induced pain by suppressing calcitonin gene-related peptide signalling and enhances the anti-tumour action of paclitaxel.
Pan C, Xu Y, Jiang Z, Fan C, Chi Z, Zhang Y, Miao M, Ren Y, Wu Z, Xu L, Mei C, Chen Q, Xi Y, Chen X
British journal of pharmacology 2024 Sep;181(17):3136-3159
British journal of pharmacology 2024 Sep;181(17):3136-3159
The CK1ε/SIAH1 axis regulates AXIN1 stability in colorectal cancer cells.
Yan M, Su Z, Pang X, Wang H, Dai H, Ning J, Liu S, Sun Q, Song J, Zhao X, Lu D
Molecular oncology 2024 Sep;18(9):2277-2297
Molecular oncology 2024 Sep;18(9):2277-2297
Sestrin2 remedies neuroinflammatory response by inhibiting A1 astrocyte conversion via autophagy.
Pan Z, Yu X, Wang W, Shen K, Chen J, Zhang Y, Huang R
Journal of neurochemistry 2024 Sep;168(9):2640-2653
Journal of neurochemistry 2024 Sep;168(9):2640-2653
Identification of prognostic biomarkers for cholangiocarcinoma by combined analysis of molecular characteristics of clinical MVI subtypes and molecular subtypes.
Li MY, Liu YH, Wei F, Zhang P, Sun XD, Wang M, Du XH, Ye JF, Qiu W, Shi XJ, Ji B, Wang YC, Jiang C, Chai WG, Huang B, Liu XK, Chen QM, Fu Y, Hu XT, Chen LG, He JX, Chai KY, Gou ZM, Yang T, Wang GY, Jiang YF, Fan ZQ, Lv GY
Genomics 2024 Sep;116(5):110889
Genomics 2024 Sep;116(5):110889
Uremic Toxin Receptor AhR Facilitates Renal Senescence and Fibrosis via Suppressing Mitochondrial Biogenesis.
Xie H, Yang N, Lu L, Sun X, Li J, Wang X, Guo H, Zhou L, Liu J, Wu H, Yu C, Zhang W, Lu L
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Sep;11(33):e2402066
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Sep;11(33):e2402066
TolDC Restores the Balance of Th17/Treg via Aryl Hydrocarbon Receptor to Attenuate Colitis.
Wang S, Xu Y, Wang L, Lin J, Xu C, Zhao X, Zhang H
Inflammatory bowel diseases 2024 Sep 3;30(9):1546-1555
Inflammatory bowel diseases 2024 Sep 3;30(9):1546-1555
Investigation of crucial genes and mitochondrial function impairment in diabetic cardiomyopathy.
Tuersuntuoheti M, Zhou L, Li J, Yang S, Zhou S, Gong H
Gene 2024 Sep 25;923:148563
Gene 2024 Sep 25;923:148563
Role of endothelial Raptor in abnormal arteriogenesis after lower limb ischaemia in type 2 diabetes.
Liu T, Zhang J, Chang F, Sun M, He J, Ai D
Cardiovascular research 2024 Sep 2;120(10):1218-1234
Cardiovascular research 2024 Sep 2;120(10):1218-1234
PDGFRα signaling regulates Srsf3 transcript binding to affect PI3K signaling and endosomal trafficking.
Forman TE, Sajek MP, Larson ED, Mukherjee N, Fantauzzo KA
bioRxiv : the preprint server for biology 2024 Sep 16;
bioRxiv : the preprint server for biology 2024 Sep 16;
PPP1r18 promotes tumor progression in esophageal squamous cell carcinoma by regulating the calcineurin-mediated ERK pathway.
Ren C, Wu L, Zhang S, Qi K, Zhang Y, Xu J, Ruan Y, Feng M
Carcinogenesis 2024 Sep 11;45(9):673-684
Carcinogenesis 2024 Sep 11;45(9):673-684
Identification of novel biomarker hsa_circ_0003914 for rheumatoid arthritis from plasma exosomes.
He Q, Sha X, Ji J, Liu W, Sun C, Gu Z
International immunopharmacology 2024 Sep 10;138:112562
International immunopharmacology 2024 Sep 10;138:112562
Nicotine induces senescence in spermatogonia stem cells by disrupting homeostasis between circadian oscillation and rhythmic mitochondrial dynamics via the SIRT6/Bmal1 pathway.
Zhang Z, Jiang Z, Cheng J, Price CA, Yang L, Li Q
Life sciences 2024 Sep 1;352:122860
Life sciences 2024 Sep 1;352:122860
LPAR6 Participates in Neuropathic Pain by Mediating Astrocyte Cells via ROCK2/NF-κB Signal Pathway.
Fan X, Chu R, Jiang X, Ma P, Chu Y, Hua T, Yang M, Ding R, Li J, Xiang Z, Yuan H
Molecular neurobiology 2024 Oct;61(10):8402-8413
Molecular neurobiology 2024 Oct;61(10):8402-8413
The Long Non-Coding RNA NR3C2-8:1 Promotes p53-Mediated Apoptosis through the miR-129-5p/USP10 Axis in Amyotrophic Lateral Sclerosis.
Pang D, Yu Y, Zhao B, Huang J, Cui Y, Li T, Li C, Shang H
Molecular neurobiology 2024 Oct;61(10):7466-7480
Molecular neurobiology 2024 Oct;61(10):7466-7480
Deletion of Tgm2 suppresses BMP-mediated hepatocyte-to-cholangiocyte metaplasia in ductular reaction.
Chen Y, Yan Y, Li Y, Zhang L, Luo T, Zhu X, Qin D, Chen N, Huang W, Chen X, Wang L, Zhu X, Zhang L
Cell proliferation 2024 Oct;57(10):e13646
Cell proliferation 2024 Oct;57(10):e13646
Quercetin Regulates Microglia M1/M2 Polarization and Alleviates Retinal Inflammation via ERK/STAT3 Pathway.
Zou Y, Jiang J, Li Y, Ding X, Fang F, Chen L
Inflammation 2024 Oct;47(5):1616-1633
Inflammation 2024 Oct;47(5):1616-1633
High Expression of miR-6785-5p in the Serum Exosomes of Psoriasis Patients Alleviates Psoriasis-Like Skin Damage by Interfering with the MNK2/p-eIF4E Axis in Keratinocytes.
Wang R, Huang Y, Shao K, Yan J, Sun Q
Inflammation 2024 Oct;47(5):1585-1599
Inflammation 2024 Oct;47(5):1585-1599
Identification of key pathways in zirconia/dental pulp stem cell composite scaffold-mediated macrophage polarization through transcriptome sequencing.
Liu B, He M, Chen B, Shuai Y, He X, Liu K, Li J, Jin L
Biotechnology & genetic engineering reviews 2024 Oct;40(2):833-857
Biotechnology & genetic engineering reviews 2024 Oct;40(2):833-857
LncRNA SLC9A3-AS1 knockdown increases the sensitivity of liver cancer cell to triptolide by regulating miR-449b-5p-mediated glycolysis.
Zhao L, Zhang H, Ren P, Sun X
Biotechnology & genetic engineering reviews 2024 Oct;40(2):1389-1405
Biotechnology & genetic engineering reviews 2024 Oct;40(2):1389-1405
Circadian gene CLOCK accelerates atherosclerosis by promoting endothelial autophagy.
Wang C, Yang X, Guo Z, Zhu G, Fan L
Biotechnology & genetic engineering reviews 2024 Oct;40(2):1230-1245
Biotechnology & genetic engineering reviews 2024 Oct;40(2):1230-1245
Dexmedetomidine attenuates ferroptosis by Keap1-Nrf2/HO-1 pathway in LPS-induced acute kidney injury.
Luo RR, Yang J, Sun YL, Zhou BY, Zhou SX, Zhang GX, Yang AX
Naunyn-Schmiedeberg's archives of pharmacology 2024 Oct;397(10):7785-7796
Naunyn-Schmiedeberg's archives of pharmacology 2024 Oct;397(10):7785-7796
Thy1-ApoE4/C/EBPβ double transgenic mice act as a sporadic model with Alzheimer's disease.
Qian Z, Wang Z, Li B, Meng X, Kuang Z, Li Y, Yang Y, Ye K
Molecular psychiatry 2024 Oct;29(10):3040-3055
Molecular psychiatry 2024 Oct;29(10):3040-3055
LncRNA MFRL regulates the phenotypic switch of vascular smooth muscle cells to attenuate arterial remodeling by encoding a novel micropeptide MFRLP.
Liu X, Chen S, Luo W, Yu C, Yan S, Lei L, Qiu S, Lin X, Feng T, Shi J, Zhang Q, Liang H, Liu X, Lee AP, Zheng L, Zhang X, Xiu J
Translational research : the journal of laboratory and clinical medicine 2024 Oct;272:54-67
Translational research : the journal of laboratory and clinical medicine 2024 Oct;272:54-67
A model of alcoholic liver disease based on different hepatotoxics leading to liver cancer.
Alarcón-Sánchez BR, Idelfonso-García OG, Guerrero-Escalera D, Piña-Vázquez C, de Anda-Jáuregui G, Pérez-Hernández JL, de la Garza M, García-Sierra F, Sánchez-Pérez Y, Baltiérrez-Hoyos R, Vásquez-Garzón VR, Muriel P, Pérez-Carreón JI, Villa-Treviño S, Arellanes-Robledo J
Biochemical pharmacology 2024 Oct;228:116209
Biochemical pharmacology 2024 Oct;228:116209
LINC00963 Promotes Cisplatin Resistance in Esophageal Squamous Cell Carcinoma by Interacting with miR-10a to Upregulate SKA1 Expression.
Hu D, Ma A, Lu H, Gao Z, Yu Y, Fan J, Liu S, Wang Y, Zhang M
Applied biochemistry and biotechnology 2024 Oct;196(10):7219-7232
Applied biochemistry and biotechnology 2024 Oct;196(10):7219-7232
Eml1 promotes axonal growth by enhancing αTAT1-mediated microtubule acetylation.
Zhang Y, Guan T, Li Z, Guo B, Luo X, Guo L, Li M, Xu M, Liu M, Liu Y
Biochimica et biophysica acta. Molecular cell research 2024 Oct;1871(7):119770
Biochimica et biophysica acta. Molecular cell research 2024 Oct;1871(7):119770
LncRNA H19/miR-107 regulates endothelial progenitor cell pyroptosis and promotes flow recovery of lower extremity ischemia through targeting FADD.
Huang L, Ye Y, Sun Y, Zhou Z, Deng T, Liu Y, Wu R, Wang K, Yao C
Biochimica et biophysica acta. Molecular basis of disease 2024 Oct;1870(7):167323
Biochimica et biophysica acta. Molecular basis of disease 2024 Oct;1870(7):167323
FTO alleviated ferroptosis in septic cardiomyopathy via mediating the m6A modification of BACH1.
Zeng H, Xu J, Wu R, Wang X, Jiang Y, Wang Q, Guo J, Xiao F
Biochimica et biophysica acta. Molecular basis of disease 2024 Oct;1870(7):167307
Biochimica et biophysica acta. Molecular basis of disease 2024 Oct;1870(7):167307
UBE2C orchestrates bone formation through stabilization of SMAD1/5.
Zhang H, Du Y, Lu D, Wang X, Li Y, Qing J, Zhang Y, Liu H, Lv L, Zhang X, Liu Y, Zhou Y, Zhang P
Bone 2024 Oct;187:117175
Bone 2024 Oct;187:117175
Identification of TACSTD2 as novel therapeutic targets for cisplatin-induced acute kidney injury by multi-omics data integration.
Deng Z, Dong Z, Wang Y, Dai Y, Liu J, Deng F
Human genetics 2024 Oct;143(9-10):1061-1080
Human genetics 2024 Oct;143(9-10):1061-1080
Plasma-derived exosomal miRNA profiles reveal potential epigenetic pathogenesis of premature ovarian failure.
Lin J, Wu Z, Zheng Y, Shen Z, Gan Z, Ma S, Liu Y, Xiong F
Human genetics 2024 Oct;143(9-10):1021-1034
Human genetics 2024 Oct;143(9-10):1021-1034
The regulation of GSH/GPX4-mediated lipid accumulation confirms that schisandra polysaccharides should be valued equally as lignans.
Xue L, Wang L, Xu Y, Shen Y, Shi Z, Li X, Feng H, Xie X, Xie L, Wang G, Liang Y
Journal of ethnopharmacology 2024 Oct 28;333:118483
Journal of ethnopharmacology 2024 Oct 28;333:118483
Elevated DNA Damage without signs of aging in the short-sleeping Mexican Cavefish.
Lloyd E, Xia F, Moore K, Zertuche C, Rastogi A, Kozol R, Kenzior O, Warren W, Appelbaum L, Moran RL, Zhao C, Duboue E, Rohner N, Keene AC
bioRxiv : the preprint server for biology 2024 Oct 21;
bioRxiv : the preprint server for biology 2024 Oct 21;
3'-Deoxyadenosin alleviates methamphetamine-induced aberrant synaptic plasticity and seeking behavior by inhibiting the NLRP3 inflammasome.
Qi Y, Zhou Y, Li J, Zhu F, Guo G, Wang C, Yu M, Wang Y, Ma T, Feng S, Zhou L
Neural regeneration research 2024 Oct 1;19(10):2270-2280
Neural regeneration research 2024 Oct 1;19(10):2270-2280
miR-1180 Targets FXYD5 to Regulate Pancreatic Cancer Cells Migration and Invasion.
Xie H, Li J, Lu M, Zhang R, Mao H
Molecular biotechnology 2024 Nov;66(11):3182-3194
Molecular biotechnology 2024 Nov;66(11):3182-3194
Gene Profiling of Circular RNAs in Keloid-prone Individuals and ceRNA Network Construction During Wound Healing.
Yang J, Zhu Z, Xu Y, Xu S, Zhang Y, Liu Z, Liu X, Shi J, Han B
Aesthetic plastic surgery 2024 Nov;48(21):4534-4545
Aesthetic plastic surgery 2024 Nov;48(21):4534-4545
Metformin attenuates PM(2.5)-induced oxidative stress by inhibiting the AhR/CYP1A1 pathway in proximal renal tubular epithelial cells.
Cui J, Chen W, Zhang D, Lu M, Huang Z, Yi B
Toxicology mechanisms and methods 2024 Nov;34(9):1022-1034
Toxicology mechanisms and methods 2024 Nov;34(9):1022-1034
Pathologic TDP-43 downregulates myelin gene expression in the monkey brain.
Zhu L, Bai D, Wang X, Ou K, Li B, Jia Q, Tan Z, Liang J, He D, Yan S, Wang L, Li S, Li XJ, Yin P
Brain pathology (Zurich, Switzerland) 2024 Nov;34(6):e13277
Brain pathology (Zurich, Switzerland) 2024 Nov;34(6):e13277
Pharmacological inhibition of astrocytic transglutaminase 2 facilitates the expression of a neurosupportive astrocyte reactive phenotype in association with increased histone acetylation.
Delgado T, Emerson J, Hong M, Keillor JW, Johnson GV
bioRxiv : the preprint server for biology 2024 Nov 11;
bioRxiv : the preprint server for biology 2024 Nov 11;
OSMR is a potential driver of inflammation in amyotrophic lateral sclerosis.
Chen W, Jiang S, Li S, Li C, Xu R
Neural regeneration research 2024 Nov 1;19(11):2513-2521
Neural regeneration research 2024 Nov 1;19(11):2513-2521
Itaconate inhibits corticosterone-induced necroptosis and neuroinflammation via up-regulating menin in HT22 cells.
Liang JY, Gao S, Jiang JM, Zhang P, Zou W, Tang XQ, Tang YY
Journal of physiology and biochemistry 2024 May;80(2):393-405
Journal of physiology and biochemistry 2024 May;80(2):393-405
Syk-dependent homologous recombination activation promotes cancer resistance to DNA targeted therapy.
Zhou Q, Tu X, Hou X, Yu J, Zhao F, Huang J, Kloeber J, Olson A, Gao M, Luo K, Zhu S, Wu Z, Zhang Y, Sun C, Zeng X, Schoolmeester KJ, Weroha JS, Hu X, Jiang Y, Wang L, Mutter RW, Lou Z
Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy 2024 May;74:101085
Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy 2024 May;74:101085
Human papillomavirus-16 E6 activates the pentose phosphate pathway to promote cervical cancer cell proliferation by inhibiting G6PD lactylation.
Meng Q, Zhang Y, Sun H, Yang X, Hao S, Liu B, Zhou H, Wang Y, Xu ZX
Redox biology 2024 May;71:103108
Redox biology 2024 May;71:103108
Highly Expressed Z-DNA Binding Protein 1 in Esophageal Cancer Promotes Tumor Growth.
Wusiman S, Liu Y, Li H, Deng Y, Qu X, Tuerxun H, Liu L
Digestive diseases and sciences 2024 May;69(5):1674-1690
Digestive diseases and sciences 2024 May;69(5):1674-1690
The Effect of Coenzyme Q10 Supplementation on Bile Acid Metabolism: Insights from Network Pharmacology, Molecular Docking, and Experimental Validation.
Jin M, Zou T, Huang H, Chen M, Zou H, Chen B, Lai C, Li H, Zhang P
Molecular nutrition & food research 2024 May;68(9):e2400147
Molecular nutrition & food research 2024 May;68(9):e2400147
Effects of the ferroptosis inducer erastin on osteogenic differentiation and biological pathways of primary osteoblasts.
Bao J, Yu X, Yang Y, Sun W, Wang Z, Chen L
Connective tissue research 2024 May;65(3):202-213
Connective tissue research 2024 May;65(3):202-213
YTHDF1 promotes the viability and self‑renewal of glioma stem cells by enhancing LINC00900 stability.
Zhang Y, Zhu Y, Zhang Y, Liu Z, Zhao X
International journal of oncology 2024 May;64(5)
International journal of oncology 2024 May;64(5)
Prokineticin-2 Participates in Chronic Constriction Injury-Triggered Neuropathic Pain and Anxiety via Regulated by NF-κB in Nucleus Accumbens Shell in Rats.
Wang W, Yuan M, Xu Y, Yang J, Wang X, Zhou Y, Yu Z, Lu Z, Wang Y, Hu C, Bai Q, Li Z
Molecular neurobiology 2024 May;61(5):2764-2783
Molecular neurobiology 2024 May;61(5):2764-2783
p53 suppresses the inflammatory response following respiratory syncytial virus infection by inhibiting TLR2.
Liu J, Gao L, Zhou N, Jiang Z, Che S, Deng Y, Zang N, Ren L, Xie X, Xie J, Liu E
Virology 2024 May;593:110018
Virology 2024 May;593:110018
Homocysteine-potentiated Kelch-like ECH-associated protein 1 promotes senescence of neuroblastoma 2a cells via inhibiting ubiquitination of β-catenin.
Zhang Y, Xie JZ, Jiang YL, Yang SJ, Wei H, Yang Y, Wang JZ
The European journal of neuroscience 2024 May;59(10):2732-2747
The European journal of neuroscience 2024 May;59(10):2732-2747
Butyrate increases methylglyoxal production through regulation of the JAK2/Stat3/Nrf2/Glo1 pathway in castration‑resistant prostate cancer cells.
Hsia YJ, Lin ZM, Zhang T, Chou TC
Oncology reports 2024 May;51(5)
Oncology reports 2024 May;51(5)
Lnc-Clic5 as a sponge for miR-212-5p to inhibit cow barn PM(2.5)-induced apoptosis in rat alveolar macrophages.
Sun K, Sun Y, Du X, Zhang X, Ma Z, Gao Y, Liang X
Toxicology 2024 May;504:153797
Toxicology 2024 May;504:153797
PFOS Elicits Cytotoxicity in Neuron Through Astrocyte-Derived CaMKII-DLG1 Signaling In Vitro Rat Hippocampal Model.
Yang J, Wang Y, Xia Y, Ren Y, Wang Z, Meng X, Li S, Liu X, Shao J
Neurochemical research 2024 May;49(5):1226-1238
Neurochemical research 2024 May;49(5):1226-1238
LRP8 promotes tumorigenesis in ovarian cancer through inhibiting p53 signaling.
Xu Y, Zhou Y, Yi X, Nie X
Cell biology international 2024 May;48(5):626-637
Cell biology international 2024 May;48(5):626-637
Mangiferin alleviates diabetic pulmonary fibrosis in mice via inhibiting endothelial-mesenchymal transition through AMPK/FoxO3/SIRT3 axis.
Fu TL, Li GR, Li DH, He RY, Liu BH, Xiong R, Xu CZ, Lu ZL, Song CK, Qiu HL, Wang WJ, Zou SS, Yi K, Li N, Geng Q
Acta pharmacologica Sinica 2024 May;45(5):1002-1018
Acta pharmacologica Sinica 2024 May;45(5):1002-1018
Characteristics of spatial protein expression in the mouse cochlear sensory epithelia: Implications for age-related hearing loss.
Lao H, Zhu Y, Yang M, Wang L, Tang J, Xiong H
Hearing research 2024 May;446:109006
Hearing research 2024 May;446:109006
A Mettl16/m(6)A/mybl2b/Igf2bp1 axis ensures cell cycle progression of embryonic hematopoietic stem and progenitor cells.
Han Y, Sun K, Yu S, Qin Y, Zhang Z, Luo J, Hu H, Dai L, Cui M, Jiang C, Liu F, Huang Y, Gao P, Chen X, Xin T, Ren X, Wu X, Song J, Wang Q, Tang Z, Chen J, Zhang H, Zhang X, Liu M, Luo D
The EMBO journal 2024 May;43(10):1990-2014
The EMBO journal 2024 May;43(10):1990-2014
Dynamic relationship among extracellular matrix and body wall cells in Hirudo verbana morphogenesis.
Pulze L, Baranzini N, Acquati F, Marcolli G, Grimaldi A
Cell and tissue research 2024 May;396(2):213-229
Cell and tissue research 2024 May;396(2):213-229
Favorable osteogenic activity of vericiguat doped in β-tricalcium phosphate: In vitro and in vivo studies.
Tao ZS, Shen CL
Journal of biomaterials applications 2024 May;38(10):1073-1086
Journal of biomaterials applications 2024 May;38(10):1073-1086
Tetramerization of pyruvate kinase M2 attenuates graft-versus-host disease by inhibition of Th1 and Th17 differentiation.
Wang M, Li QJ, Zhao HY, Zhang JL
Human cell 2024 May;37(3):633-647
Human cell 2024 May;37(3):633-647
Selective Organ-Targeting Hafnium Oxide Nanoparticles with Multienzyme-Mimetic Activities Attenuate Radiation-Induced Tissue Damage.
Liu D, Cao F, Xu Z, Zhao C, Liu Z, Pang J, Liu ZX, Moghiseh M, Butler A, Liang S, Fan W, Yang J
Advanced materials (Deerfield Beach, Fla.) 2024 May;36(19):e2308098
Advanced materials (Deerfield Beach, Fla.) 2024 May;36(19):e2308098
Construction of functional neural network tissue combining CBD-NT3-modified linear-ordered collagen scaffold and TrkC-modified iPSC-derived neural stem cells for spinal cord injury repair.
Wu Z, Zhou Y, Hou X, Liu W, Yin W, Wang L, Cao Y, Jiang Z, Guo Y, Chen Q, Xie W, Wang Z, Shi N, Liu Y, Gao X, Luo L, Dai J, Ren C, Jiang X
Bioactive materials 2024 May;35:242-258
Bioactive materials 2024 May;35:242-258
Combining large-spot low-fluence 1064-nm and fractional 1064-nm picosecond lasers for promoting protective melanosome autophagy via the PI3K/Akt/mTOR signalling pathway for the treatment of melasma.
Shen J, Jin J, Huang J, Guo Y, Qian Q
Experimental dermatology 2024 May;33(5):e15094
Experimental dermatology 2024 May;33(5):e15094
Dual-inhibition of NAMPT and PAK4 induces anti-tumor effects in 3D-spheroids model of platinum-resistant ovarian cancer.
Kudo K, Greer YE, Yoshida T, Harrington BS, Korrapati S, Shibuya Y, Henegar L, Kopp JB, Fujii T, Lipkowitz S, Annunziata CM
Cancer gene therapy 2024 May;31(5):721-735
Cancer gene therapy 2024 May;31(5):721-735
SLC25A3 negatively regulates NLRP3 inflammasome activation by restricting the function of NLRP3.
Xiao F, Jia Y, Zhang S, Liu N, Zhang X, Wang T, Qiao J, Yang G, Che X, Chen K, Pan P, Zhou L, Sun B, Chen J, Wan P
The Journal of biological chemistry 2024 May;300(5):107233
The Journal of biological chemistry 2024 May;300(5):107233
Epstein-Barr virus suppresses N(6)-methyladenosine modification of TLR9 to promote immune evasion.
Zhang X, Li Z, Peng Q, Liu C, Wu Y, Wen Y, Zheng R, Xu C, Tian J, Zheng X, Yan Q, Wang J, Ma J
The Journal of biological chemistry 2024 May;300(5):107226
The Journal of biological chemistry 2024 May;300(5):107226
The tumor suppressor NF2 modulates TEAD4 stability and activity in Hippo signaling via direct interaction.
Wu M, Hu L, He L, Yuan L, Yang L, Zhao B, Zhang L, He X
The Journal of biological chemistry 2024 May;300(5):107212
The Journal of biological chemistry 2024 May;300(5):107212
Electroacupuncture regulates Rab5a-mediating NGF transduction to improve learning and memory ability in the early stage of AD mice.
Li J, Yang M, Dai Y, Guo X, Ding Y, Li X, Zhang S, Xu W, Chen L, Tao J, Liu W
CNS neuroscience & therapeutics 2024 May;30(5):e14743
CNS neuroscience & therapeutics 2024 May;30(5):e14743
Inhibition of ADORA3 promotes microglial phagocytosis and alleviates chronic ischemic white matter injury.
Xu Y, Tang L, Zhou C, Sun L, Hu Y, Zhang Z, Xia S, Bao X, Yang H, Xu Y
CNS neuroscience & therapeutics 2024 May;30(5):e14742
CNS neuroscience & therapeutics 2024 May;30(5):e14742
Regulation of osteoclast differentiation and inflammatory signaling by TCF8 in periodontitis.
Sun S, Yan T, Yang N, Wu J, Liu Z
Oral diseases 2024 May;30(4):2580-2591
Oral diseases 2024 May;30(4):2580-2591
LINC00525 promotes tumour growth and epithelial-mesenchymal transition as an oncogene in oral squamous cell carcinoma.
Du J, Su W, Li X, Zu T, Bai J, Zhang W, Zhou W
Oral diseases 2024 May;30(4):2051-2062
Oral diseases 2024 May;30(4):2051-2062
CDK5-mediated rearrangement of vimentin during Duck Tembusu virus infection inhibits viral replication.
Bao G, Fan S, Hu C, Li C, Ma F, Wang G, Fan H, Wang Q
Veterinary microbiology 2024 May;292:110071
Veterinary microbiology 2024 May;292:110071
NMDA receptor within nucleus accumbens shell regulates propofol self-administration through D1R/ERK/CREB signalling pathway.
Li J, Pan C, Huang B, Qiu J, Jiang C, Dong Z, Li J, Lian Q, Wu B
Addiction biology 2024 May;29(5):e13401
Addiction biology 2024 May;29(5):e13401
Glutathione peroxidase 4 restrains temporomandibular joint osteoarthritis progression by inhibiting ferroptosis.
Pang C, Zhang H, Liu Y, Tang N, Tian K, Mu Y, Li X, Xiao L
Journal of cellular and molecular medicine 2024 May;28(9):e18377
Journal of cellular and molecular medicine 2024 May;28(9):e18377
Decreased intranuclear cardiac troponin I impairs cardiac autophagy through FOS/ATG5 in ageing hearts.
Liu RM, Huang S, Hu D, Liu L, Sun HC, Tian J, Pan B
Journal of cellular and molecular medicine 2024 May;28(9):e18357
Journal of cellular and molecular medicine 2024 May;28(9):e18357
Epigenetic regulation by KDM5A mediates the effects of prenatal PM(2.5) exposure on hippocampal development and synaptic integrity through the Shh signaling pathway.
Huang J, Song C, Liu Y, Zhang T, Wang T, Liu X, Yu L
Ecotoxicology and environmental safety 2024 May;276:116311
Ecotoxicology and environmental safety 2024 May;276:116311
Biomass fuels related-PM(2.5) promotes lung fibroblast-myofibroblast transition through PI3K/AKT/TRPC1 pathway.
Li S, Qu L, Zhou L, Zhan N, Liu L, Ling Y, Chen Q, Lai W, Lin N, Li J
Ecotoxicology and environmental safety 2024 May;276:116309
Ecotoxicology and environmental safety 2024 May;276:116309
Nicotinamide ribose ameliorates myocardial ischemia/reperfusion injury by regulating autophagy and regulating oxidative stress.
Yuan C, Yang H, Lan W, Yang J, Tang Y
Experimental and therapeutic medicine 2024 May;27(5):187
Experimental and therapeutic medicine 2024 May;27(5):187
LncRNA lncMGR regulates skeletal muscle development and regeneration by recruiting CDK9 and sponging miRNAs.
Guo Y, Geng W, Chen Z, Zhi Y, Zhang K, Li Z, Li G, Kang X, Tian W, Li H, Liu X
International journal of biological macromolecules 2024 May;266(Pt 2):131049
International journal of biological macromolecules 2024 May;266(Pt 2):131049
LPCAT1-mediated membrane phospholipid remodelling promotes ferroptosis evasion and tumour growth.
Li Z, Hu Y, Zheng H, Li M, Liu Y, Feng R, Li X, Zhang S, Tang M, Yang M, Yu R, Xu Y, Liao X, Chen S, Qian W, Zhang Q, Tang D, Li B, Song L, Li J
Nature cell biology 2024 May;26(5):811-824
Nature cell biology 2024 May;26(5):811-824
Endurance training increases mitochondrial myoglobin and enhances its interaction with complex IV in rat plantaris muscle.
Koma R, Shibaguchi T, Yamada T, Nonaka Y, Jue T, Yamazaki A, Masuda K
Acta physiologica (Oxford, England) 2024 May;240(5):e14139
Acta physiologica (Oxford, England) 2024 May;240(5):e14139
KLF13 promotes VSMCs phenotypic dedifferentiation by directly binding to the SM22α promoter.
Yuan X, Jiang C, Xue Y, Guo F, Luo M, Guo L, Gao Y, Yuan T, Xu H, Chen H
Journal of cellular physiology 2024 May;239(5):e31251
Journal of cellular physiology 2024 May;239(5):e31251
circUSP13 facilitates the fast-to-slow myofiber shift via the MAPK/ERK signaling pathway in goat skeletal muscles.
Zhang Z, Kang Z, Deng K, Li J, Liu Z, Huang X, Wang F, Fan Y
Journal of cellular physiology 2024 May;239(5):e31226
Journal of cellular physiology 2024 May;239(5):e31226
m(6)A-induced TRIB3 regulates Hippo pathway through interacting with LATS1 to promote the progression of lung adenocarcinoma.
Wu J, Yi T, Zhuo C, Wang D, Zhang M, Hu R, Wu D, Hou G, Xing Y
Journal of cellular physiology 2024 May;239(5):e31220
Journal of cellular physiology 2024 May;239(5):e31220
N-homocysteinylation of DJ-1 promotes neurodegeneration in Parkinson's disease.
Guo T, Zhou L, Xiong M, Xiong J, Huang J, Li Y, Zhang G, Chen G, Wang ZH, Xiao T, Hu D, Bao A, Zhang Z
Aging cell 2024 May;23(5):e14124
Aging cell 2024 May;23(5):e14124
PLCE1 enhances mitochondrial dysfunction to promote GSDME-mediated pyroptosis in doxorubicin-induced cardiotoxicity.
Tuersuntuoheti M, Peng F, Li J, Zhou L, Gao H, Gong H
Biochemical pharmacology 2024 May;223:116142
Biochemical pharmacology 2024 May;223:116142
Human disease-causing mutations result in loss of leiomodin 2 through nonsense-mediated mRNA decay.
Pappas CT, Mayfield RM, Dickerson AE, Mi-Mi L, Gregorio CC
PLoS genetics 2024 May;20(5):e1011279
PLoS genetics 2024 May;20(5):e1011279
Conditioned medium from human dental pulp stem cells treats spinal cord injury by inhibiting microglial pyroptosis.
Liu T, Ma Z, Liu L, Pei Y, Wu Q, Xu S, Liu Y, Ding N, Guan Y, Zhang Y, Chen X
Neural regeneration research 2024 May;19(5):1105-1111
Neural regeneration research 2024 May;19(5):1105-1111
Untargeted metabolomic reveals the changes in muscle metabolites of mice during exercise recovery and the mechanisms of whey protein and whey protein hydrolysate in promoting muscle repair.
Zhao C, Gong Y, Zheng L, Zhao M
Food research international (Ottawa, Ont.) 2024 May;184:114261
Food research international (Ottawa, Ont.) 2024 May;184:114261
Interferon-α induces differentiation of cancer stem cells and immunosuppression in hepatocellular carcinoma by upregulating CXCL8 secretion.
Ma YT, Zheng L, Zhao CW, Zhang Y, Xu XW, Wang XY, Niu GP, Man ZS, Gu F, Chen YQ
Cytokine 2024 May;177:156555
Cytokine 2024 May;177:156555
Sacubitril/Valsartan inhibits M1 type macrophages polarization in acute myocarditis by targeting C-type natriuretic peptide.
Liu C, Long Q, Yang H, Yang H, Tang Y, Liu B, Zhou Z, Yuan J
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 May;174:116535
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 May;174:116535
Resveratrol protects against myocardial ischemic injury in obese mice via activating SIRT3/FOXO3a signaling pathway and restoring redox homeostasis.
Zhu X, Ma E, Ge Y, Yuan M, Guo X, Peng J, Zhu W, Ren DN, Wo D
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 May;174:116476
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 May;174:116476
DMC-siERCC2 hybrid nanoparticle enhances TRAIL sensitivity by inducing cell cycle arrest for glioblastoma treatment.
Song M, Wang T, Liu T, Lei T, Teng X, Peng Q, Zhu Q, Chen F, Zhao G, Li K, Qi L
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 May;174:116470
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 May;174:116470
Cornus officinalis with high pressure wine steaming enhanced anti-hepatic fibrosis: Possible through SIRT3-AMPK axis.
Han X, Ning Y, Dou X, Wang Y, Shan Q, Shi K, Wang Z, Ding C, Hao M, Wang K, Peng M, Kuang H, Yang Q, Sang X, Cao G
Journal of pharmaceutical analysis 2024 May;14(5):100927
Journal of pharmaceutical analysis 2024 May;14(5):100927
Pirfenidone alleviates fibrosis by acting on tumour-stroma interplay in pancreatic cancer.
Lei Y, Xu J, Xiao M, Wu D, Xu H, Yang J, Mao X, Pan H, Yu X, Shi S
British journal of cancer 2024 May;130(9):1505-1516
British journal of cancer 2024 May;130(9):1505-1516
Proton pump inhibitors stabilize the expression of PD-L1 on cell membrane depending on the phosphorylation of GSK3β.
Gao L, Liu Y, Liu J, Li J, Li H, Liu Y, Meng F, Du X, Gao Y, Li J, Qin FX
Cancer medicine 2024 May;13(10):e7083
Cancer medicine 2024 May;13(10):e7083
A comprehensive comparison of molecular and phenotypic profiles between hepatitis B virus (HBV)-infected and non-HBV-infected hepatocellular carcinoma by multi-omics analysis.
Wu Z, Dong Z, Luo J, Hu W, Tong Y, Gao X, Yao W, Tian H, Wang X
Genomics 2024 May;116(3):110831
Genomics 2024 May;116(3):110831
Urolithin A Hijacks ERK1/2-ULK1 Cascade to Improve CD8(+) T Cell Fitness for Antitumor Immunity.
Ma S, Wu Q, Wu W, Tian Y, Zhang J, Chen C, Sheng X, Zhao F, Ding L, Wang T, Zhao L, Xie Y, Wang Y, Yue X, Wu Z, Wei J, Zhang K, Liang X, Gao L, Wang H, Wang G, Li C, Ma C
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 May;11(18):e2310065
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 May;11(18):e2310065
Molybdenum and cadmium co-induce apoptosis and ferroptosis through inhibiting Nrf2 signaling pathway in duck (Anas platyrhyncha) testes.
Zhu J, Dai X, Wang Y, Cui T, Huang B, Wang D, Pu W, Zhang C
Poultry science 2024 May;103(5):103653
Poultry science 2024 May;103(5):103653
Knocking-down long non-coding RNA LINC01094 prohibits chondrocyte apoptosis via regulating microRNA-577/metal-regulatory transcription factor 1 axis.
Huang F, Su Z, Yang J, Zhao X, Xu Y
Journal of orthopaedic surgery (Hong Kong) 2024 May-Aug;32(2):10225536241254588
Journal of orthopaedic surgery (Hong Kong) 2024 May-Aug;32(2):10225536241254588
Design, Synthesis, and Biological Evaluation of Novel EGFR PROTACs Targeting C797S Mutation.
Zhu Y, Ye X, Wu Y, Shen H, Cai Z, Xia F, Min W, Hou Y, Wang L, Wang X, Xiao Y, Yang P
Journal of medicinal chemistry 2024 May 9;67(9):7283-7300
Journal of medicinal chemistry 2024 May 9;67(9):7283-7300
Discovery of a Potent Dual Son of Sevenless 1 (SOS1) and Epidermal Growth Factor Receptor (EGFR) Inhibitor for the Treatment of Prostate Cancer.
Zheng L, Zhang Y, Mei S, Xie T, Zou Y, Wang Y, Jing H, Xu S, Dramou P, Xu Z, Li J, Zhou Y, Niu MM
Journal of medicinal chemistry 2024 May 9;67(9):7130-7145
Journal of medicinal chemistry 2024 May 9;67(9):7130-7145
Gemfibrozil-Platinum(IV) Precursors for New Enhanced-Starvation and Chemotherapy In Vitro and In Vivo.
Song XQ, Guo X, Ding YX, Han YX, You ZH, Song Y, Yuan Y, Li L
Journal of medicinal chemistry 2024 May 9;67(9):7033-7047
Journal of medicinal chemistry 2024 May 9;67(9):7033-7047
Autologous patient-derived exhausted nano T-cells exploit tumor immune evasion to engage an effective cancer therapy.
Blaya-Cánovas JL, Griñán-Lisón C, Blancas I, Marchal JA, Ramírez-Tortosa C, López-Tejada A, Benabdellah K, Cortijo-Gutiérrez M, Cano-Cortés MV, Graván P, Navarro-Marchal SA, Gómez-Morales J, Delgado-Almenta V, Calahorra J, Agudo-Lera M, Sagarzazu A, Rodríguez-González CJ, Gallart-Aragón T, Eich C, Sánchez-Martín RM, Granados-Principal S
Molecular cancer 2024 May 9;23(1):83
Molecular cancer 2024 May 9;23(1):83
Mesencephalic astrocyte-derived neurotrophic factor ameliorates inflammatory response in polycystic ovary syndrome via inhibiting TLR4-NF-κB-NLRP3 pathway.
Yu S, Hou C, Zhang X, Wei Z
Biochemical and biophysical research communications 2024 May 7;707:149782
Biochemical and biophysical research communications 2024 May 7;707:149782
Gut bacteria-driven homovanillic acid alleviates depression by modulating synaptic integrity.
Zhao M, Ren Z, Zhao A, Tang Y, Kuang J, Li M, Chen T, Wang S, Wang J, Zhang H, Wang J, Zhang T, Zeng J, Liu X, Xie G, Liu P, Sun N, Bao T, Nie T, Lin J, Liu P, Zheng Y, Zheng X, Liu T, Jia W
Cell metabolism 2024 May 7;36(5):1000-1012.e6
Cell metabolism 2024 May 7;36(5):1000-1012.e6
Disruption of maternal vascular remodeling by a fetal endoretrovirus-derived gene in preeclampsia.
Gong X, He W, Jin W, Ma H, Wang G, Li J, Xiao Y, Zhao Y, Chen Q, Guo H, Yang J, Qi Y, Dong W, Fu M, Li X, Liu J, Liu X, Yin A, Zhang Y, Wei Y
Genome biology 2024 May 7;25(1):117
Genome biology 2024 May 7;25(1):117
Polymorphism rs2327430 in TCF21 predicts the risk and prognosis of gastric cancer by affecting the binding between TFAP2A and TCF21.
Zhou X, Shen K, Cao S, Li P, Xiao J, Dong J, Cheng Q, Hu L, Xu Z, Yang L
Cancer cell international 2024 May 7;24(1):159
Cancer cell international 2024 May 7;24(1):159
Identification of immunogenic cell death-related damage-related molecular patterns (DAMPs) to predict outcomes in patients with head and neck squamous cell carcinoma.
Zhang J, Shi X, Wang M, Zhai R, Wang M, Gong Z, Ni Z, Xu T, Zhu W, Liu L
Journal of cancer research and clinical oncology 2024 May 7;150(5):240
Journal of cancer research and clinical oncology 2024 May 7;150(5):240
Esaxerenone Inhibits Interferon-γ Induced Pyroptosis of Macrophages in the Lungs of Aldosterone-treated Mice.
Chang J, Gao X, Yang F, Qiang P, Fan L, Liu Z, Shimosawa T, Xu Q, Chang Y
Inflammation 2024 May 7;
Inflammation 2024 May 7;
Dendritic-cell-targeting virus-like particles as potent mRNA vaccine carriers.
Yin D, Zhong Y, Ling S, Lu S, Wang X, Jiang Z, Wang J, Dai Y, Tian X, Huang Q, Wang X, Chen J, Li Z, Li Y, Xu Z, Jiang H, Wu Y, Shi Y, Wang Q, Xu J, Hong W, Xue H, Yang H, Zhang Y, Da L, Han ZG, Tao SC, Dong R, Ying T, Hong J, Cai Y
Nature biomedical engineering 2024 May 7;
Nature biomedical engineering 2024 May 7;
Varespladib mitigates acute liver injury via suppression of excessive mitophagy on Naja atra envenomed mice by inhibiting PLA(2).
Zhao W, Liu J, Wang S, Tao Q, Lei Q, Huang C
Toxicon : official journal of the International Society on Toxinology 2024 May 6;242:107694
Toxicon : official journal of the International Society on Toxinology 2024 May 6;242:107694
A TBK1 variant causes autophagolysosomal and motoneuron pathology without neuroinflammation in mice.
Brenner D, Sieverding K, Srinidhi J, Zellner S, Secker C, Yilmaz R, Dyckow J, Amr S, Ponomarenko A, Tunaboylu E, Douahem Y, Schlag JS, Rodríguez Martínez L, Kislinger G, Niemann C, Nalbach K, Ruf WP, Uhl J, Hollenbeck J, Schirmer L, Catanese A, Lobsiger CS, Danzer KM, Yilmazer-Hanke D, Münch C, Koch P, Freischmidt A, Fetting M, Behrends C, Parlato R, Weishaupt JH
The Journal of experimental medicine 2024 May 6;221(5)
The Journal of experimental medicine 2024 May 6;221(5)
Modified Lichong decoction intervenes in colorectal cancer by modulating the intestinal flora and the Wnt/β-catenin signaling pathway.
Liu L, Zhao M, Lang X, Jia S, Kang X, Liu Y, Liu J
Journal of cancer research and clinical oncology 2024 May 6;150(5):234
Journal of cancer research and clinical oncology 2024 May 6;150(5):234
Activation of CaMKII/HDAC4 by SDF1 contributes to pulmonary arterial hypertension via stabilization Runx2.
Chen Y, Liu J, Zhang Q, Chai L, Chen H, Li D, Wang Y, Qiu Y, Shen N, Zhang J, Wang Q, Wang J, Xie X, Li S, Li M
European journal of pharmacology 2024 May 5;970:176483
European journal of pharmacology 2024 May 5;970:176483
Maternal prednisone exposure during pregnancy elevates susceptibility to osteoporosis in female offspring: The role of mitophagy/FNDC5 alteration in skeletal muscle.
Du ZY, Zhu HL, Chang W, Zhang YF, Ling Q, Wang KW, Zhang J, Zhang QB, Kan XL, Wang QN, Wang H, Zhou Y
Journal of hazardous materials 2024 May 5;469:133997
Journal of hazardous materials 2024 May 5;469:133997
Design, synthesis, and evaluation of novel quindoline derivatives with fork-shaped side chains as RNA G-quadruplex stabilizers for repressing oncogene NRAS translation.
Sun JW, Zou J, Zheng Y, Yuan H, Xie YZ, Wang XN, Ou TM
European journal of medicinal chemistry 2024 May 5;271:116406
European journal of medicinal chemistry 2024 May 5;271:116406
Design, synthesis and evaluation of a pyrazolo[3,4-d]pyrimidine derivative as a novel and potent TGFβ1R1 inhibitor.
Wang Y, Liu Y, Zhang Y, Zhang Z, Xu L, Wang J, Yang Y, Hu B, Yao Y, Wei M, Wang J, Tang B, Zhang K, Liu S, Yang G
European journal of medicinal chemistry 2024 May 5;271:116395
European journal of medicinal chemistry 2024 May 5;271:116395
IRF7 from the black flying fox induces a STAT1-independent ISG response in unstimulated cell lines that protects against diverse RNA viruses.
Cruz-Rivera PC, Eitson JL, Schoggins JW
bioRxiv : the preprint server for biology 2024 May 5;
bioRxiv : the preprint server for biology 2024 May 5;
Vasorin promotes endothelial differentiation of glioma stem cells via stimulating the transcription of VEGFR2.
Qin Z, Zhong Y, Li P, Ma Z, Kang H, Huang Y, Zhong Y, Wang L
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 May 31;38(10):e23682
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 May 31;38(10):e23682
Melatonin suppresses atherosclerosis by ferroptosis inhibition via activating NRF2 pathway.
Tao Y, Zhao Q, Lu C, Yong W, Xu M, Wang Z, Leng X
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 May 31;38(10):e23678
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 May 31;38(10):e23678
Methyl-CpG-binding protein 2 regulates CYP27A1-induced myometrial contraction during preterm labor.
Peng T, Cui J, Ni Z, Tang Y, Cao X, Li S, Cheng X, Huang J
Molecular human reproduction 2024 May 30;30(6)
Molecular human reproduction 2024 May 30;30(6)
Genkwanin alleviates intervertebral disc degeneration via regulating ITGA2/PI3K/AKT pathway and inhibiting apoptosis and senescence.
Li M, Yu X, Chen X, Jiang Y, Zeng Y, Ren R, Nie M, Zhang Z, Bao Y, Kang H
International immunopharmacology 2024 May 30;133:112101
International immunopharmacology 2024 May 30;133:112101
Ivermectin ameliorates acute myocarditis via the inhibition of importin-mediated nuclear translocation of NF-κB/p65.
Gao X, Xuan Y, Zhou Z, Chen C, Wen Wang D, Wen Z
International immunopharmacology 2024 May 30;133:112073
International immunopharmacology 2024 May 30;133:112073
FOXF1 reverses lung fibroblasts transdifferentiation via inhibiting TGF-β/SMAD2/3 pathway in silica-induced pulmonary fibrosis.
Hu B, Zhang X, Fan H, Jin X, Qi Y, Liu R, Li X, Duan M, Zhang C, Li S, Yao W, Hao C
International immunopharmacology 2024 May 30;133:112067
International immunopharmacology 2024 May 30;133:112067
Elevated microRNA-214-3p level ameliorates neuroinflammation after spinal cord ischemia-reperfusion injury by inhibiting Nmb/Cav3.2 pathway.
Xia GQ, Xu M, Sun C, Zhang ZL, Li XQ
International immunopharmacology 2024 May 30;133:112031
International immunopharmacology 2024 May 30;133:112031
The therapeutic effect and targets of herba Sarcandrae on breast cancer and the construction of a prognostic signature consisting of inflammation-related genes.
Yuan J, Lin M, Yang S, Yin H, Ouyang S, Xie H, Tang H, Ou X, Zeng Z
Heliyon 2024 May 30;10(10):e31137
Heliyon 2024 May 30;10(10):e31137
LC-MS-based rheumatoid arthritis serum metabolomics reveals the role of deoxyinosine in attenuating collagen-induced arthritis in mice.
Xu D, Tang L, Wang Y, Pan J, Su C
Heliyon 2024 May 30;10(10):e30903
Heliyon 2024 May 30;10(10):e30903
Armcx1 Reduces Neurological Damage Via a Mitochondrial Transport Pathway Involving Miro1 After Traumatic Brain Injury.
Li Q, Ni H, Rui Q, Ding J, Kong X, Kan X, Gao R, Shen H
Neuroscience 2024 May 3;545:111-124
Neuroscience 2024 May 3;545:111-124
Targeting the molecular chaperone CCT2 inhibits GBM progression by influencing KRAS stability.
Zhao F, Yao Z, Li Y, Zhao W, Sun Y, Yang X, Zhao Z, Huang B, Wang J, Li X, Chen A
Cancer letters 2024 May 28;590:216844
Cancer letters 2024 May 28;590:216844
SOD1-high fibroblasts derived exosomal miR-3960 promotes cisplatin resistance in triple-negative breast cancer by suppressing BRSK2-mediated phosphorylation of PIMREG.
Li K, Lin H, Liu A, Qiu C, Rao Z, Wang Z, Chen S, She X, Zhu S, Li P, Liu L, Wu Q, Wang G, Xu F, Li S
Cancer letters 2024 May 28;590:216842
Cancer letters 2024 May 28;590:216842
The Mediator Med23 controls a transcriptional switch for muscle stem cell proliferation and differentiation in muscle regeneration.
Fang Y, Yuan C, Li C, Lu C, Yu W, Wang G
Cell reports 2024 May 28;43(5):114177
Cell reports 2024 May 28;43(5):114177
Paclitaxel-induced Immune Dysfunction and Activation of Transcription Factor AP-1 Facilitate Hepatitis B Virus Replication.
Chen S, Li B, Luo W, Rehman AU, He M, Yang Q, Wang S, Guo J, Chen L, Li X
Journal of clinical and translational hepatology 2024 May 28;12(5):457-468
Journal of clinical and translational hepatology 2024 May 28;12(5):457-468
Nur77 inhibition of β-catenin expression mediates Hepatoblastoma progression and enhances cisplatin's therapeutic effect.
Zhou J, Liu X, Yin H, Zhou Y, Xu Z, Zhou K, Li T, Fang Y, Shen Q
Gene 2024 May 25;908:148292
Gene 2024 May 25;908:148292
Accumulated LPS induced by colitis altered the activities of vitamin D-metabolizing hydroxylases and decreased the generation of 25-hydroxyvitamin D.
Lu Y, Chen H, Chen Y, Zhao L, Hou S
Chemico-biological interactions 2024 May 25;395:110997
Chemico-biological interactions 2024 May 25;395:110997
Usp14 deficiency removes α-synuclein by regulating S100A8/A9 in Parkinson's disease.
Ding L, Lu L, Zheng S, Zhang Z, Huang X, Ma R, Zhang M, Xu Z, Chen M, Guo Z, Zhu S, Gong J, Mao H, Zhang W, Xu P
Cellular and molecular life sciences : CMLS 2024 May 23;81(1):232
Cellular and molecular life sciences : CMLS 2024 May 23;81(1):232
Activation of Nrf2/HO-1 signaling pathway exacerbates cholestatic liver injury.
Wang Y, Fu X, Zeng L, Hu Y, Gao R, Xian S, Liao S, Huang J, Yang Y, Liu J, Jin H, Klaunig J, Lu Y, Zhou S
Communications biology 2024 May 23;7(1):621
Communications biology 2024 May 23;7(1):621
Design of FK866-Based Degraders for Blocking the Nonenzymatic Functions of Nicotinamide Phosphoribosyltransferase.
Lu T, Chen F, Yao J, Bu Z, Kyani A, Liang B, Chen S, Zheng Y, Liang H, Neamati N, Liu Y
Journal of medicinal chemistry 2024 May 23;67(10):8099-8121
Journal of medicinal chemistry 2024 May 23;67(10):8099-8121
NEK2 contributes to radioresistance in esophageal squamous cell carcinoma by inducing protective autophagy via regulating TRIM21.
Guo D, Zhou S, Liu R, Yao W, Li S, Zhang X, Shen W, Zhu S
Cancer cell international 2024 May 23;24(1):179
Cancer cell international 2024 May 23;24(1):179
APC/C-regulated CPT1C promotes tumor progression by upregulating the energy supply and accelerating the G1/S transition.
Zhao H, Cheng X, Yan L, Mi F, Wang W, Hu Y, Liu X, Fan Y, Min Q, Wang Y, Zhang W, Wu Q, Zhan Q
Cell communication and signaling : CCS 2024 May 23;22(1):283
Cell communication and signaling : CCS 2024 May 23;22(1):283
Pacidusin B isolated from Phyllanthus acidus triggers ferroptotic cell death in HT1080 cells.
Zhu G, Luo D, Zhao Y, Xiang Z, Chen C, Li N, Hao X, Ding X, Zhang Y, Zhao Y
Natural products and bioprospecting 2024 May 23;14(1):34
Natural products and bioprospecting 2024 May 23;14(1):34
RNA-binding properties orchestrate TDP-43 homeostasis through condensate formation in vivo.
Scherer NM, Maurel C, Graus MS, McAlary L, Richter G, Radford RAW, Hogan A, Don EK, Lee A, Yerbury J, Francois M, Chung RS, Morsch M
Nucleic acids research 2024 May 22;52(9):5301-5319
Nucleic acids research 2024 May 22;52(9):5301-5319
Activity reconstitution of Kre33 and Tan1 reveals a molecular ruler mechanism in eukaryotic tRNA acetylation.
Ma CR, Liu N, Li H, Xu H, Zhou XL
Nucleic acids research 2024 May 22;52(9):5226-5240
Nucleic acids research 2024 May 22;52(9):5226-5240
WSB1/2 target chromatin-bound lysine-methylated RelA for proteasomal degradation and NF-κB termination.
Zhang J, Yu Y, Zou X, Du Y, Liang Q, Gong M, He Y, Luo J, Wu D, Jiang X, Sinclair M, Tajkhorshid E, Chen HZ, Hou Z, Zheng Y, Chen LF, Yang XD
Nucleic acids research 2024 May 22;52(9):4969-4984
Nucleic acids research 2024 May 22;52(9):4969-4984
Methylation-regulated tumor suppressor gene PDE7B promotes HCC invasion and metastasis through the PI3K/AKT signaling pathway.
Du Y, Xu Y, Guo X, Tan C, Zhu X, Liu G, Lyu X, Bei C
BMC cancer 2024 May 22;24(1):624
BMC cancer 2024 May 22;24(1):624
TRIM65 promotes renal cell carcinoma through ubiquitination and degradation of BTG3.
Zhang Q, Li Y, Zhu Q, Xie T, Xiao Y, Zhang F, Li N, Deng K, Xin H, Huang X
Cell death & disease 2024 May 22;15(5):355
Cell death & disease 2024 May 22;15(5):355
Exposure to Selenomethionine and Selenocystine Induces Redox-Mediated ER Stress in Normal Breast Epithelial MCF-10A Cells.
Dauplais M, Romero S, Lazard M
Biological trace element research 2024 May 22;
Biological trace element research 2024 May 22;
Dexamethasone-Integrated Mesenchymal Stem Cells for Systemic Lupus Erythematosus Treatment via Multiple Immunomodulatory Mechanisms.
Ma W, Che J, Chen W, Wang D, Zhang H, Zhao Y
ACS nano 2024 May 21;18(20):13249-13265
ACS nano 2024 May 21;18(20):13249-13265
Implications of LAG3 and CTLA4 immune checkpoints beyond PD-1/PD-L1 as a potential target in determining the prognosis of uveal melanoma patients.
Kashyap S, Singh MK, Kumar N, Jha J, Lomi N, Meel R, Bakhshi S, Sen S, Singh L
The British journal of ophthalmology 2024 May 21;108(6):903-912
The British journal of ophthalmology 2024 May 21;108(6):903-912
Antiviral Activities of Heparan Sulfate Mimetic RAFT Polymers Against Mosquito-borne Viruses.
Nahain AA, Li J, Modhiran N, Watterson D, Li JP, Ignjatovic V, Monagle P, Tsanaktsidis J, Vamvounis G, Ferro V
ACS applied bio materials 2024 May 20;7(5):2862-2871
ACS applied bio materials 2024 May 20;7(5):2862-2871
Ginsenoside Rk1 improves endothelial function in diabetes through activating peroxisome proliferator-activated receptors.
Miao L, Zhou Y, Tan D, Zhou C, Ruan CC, Wang S, Wang Y, Vong CT, Cheang WS
Food & function 2024 May 20;15(10):5485-5495
Food & function 2024 May 20;15(10):5485-5495
MILIP Binding to tRNAs Promotes Protein Synthesis to Drive Triple-Negative Breast Cancer.
Zheng SM, Feng YC, Zhu Q, Li RQ, Yan QQ, Teng L, Yue YM, Han MM, Ye K, Zhang SN, Qi TF, Tang CX, Zhao XH, Zhang YY, Xu L, Xu R, Xing J, Baker M, Liu T, Thorne RF, Jin L, Preiss T, Zhang XD, Cang S, Gao JN
Cancer research 2024 May 2;84(9):1460-1474
Cancer research 2024 May 2;84(9):1460-1474
TRIM14 suppressed the progression of NSCLC via hexosamine biosynthesis pathway.
Wei S, Ai M, Zhan Y, Yu J, Xie T, Hu Q, Fang Y, Huang X, Li Y
Carcinogenesis 2024 May 19;45(5):324-336
Carcinogenesis 2024 May 19;45(5):324-336
Fluoride Induces Neurocytotoxicity by Disrupting Lysosomal Iron Metabolism and Membrane Permeability.
Xu P, Xing H, Ma Y, Ding X, Li T, Zhang Y, Liu L, Ma J, Niu Q
Biological trace element research 2024 May 18;
Biological trace element research 2024 May 18;
Aurora-A condensation mediated by BuGZ aids its mitotic centrosome functions.
Zheng H, Zhang Q, Liu X, Shi F, Yang F, Xiang S, Jiang H
iScience 2024 May 17;27(5):109785
iScience 2024 May 17;27(5):109785
The acetylation of MDH1 and IDH1 is associated with energy metabolism in acute liver failure.
Shi C, Zhang Y, Chen Q, Wang Y, Zhang D, Guo J, Zhang Q, Zhang W, Gong Z
iScience 2024 May 17;27(5):109678
iScience 2024 May 17;27(5):109678
Positive Effect of 6-Gingerol on Functional Plasticity of Microglia in a rat Model of LPS-induced Depression.
Liu C, Zhao Y, Zhao WJ
Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology 2024 May 17;19(1):20
Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology 2024 May 17;19(1):20
TRIM37 is a primate-specific E3 ligase for Huntingtin and accounts for the striatal degeneration in Huntington's disease.
Qin Y, Chen L, Zhu W, Song J, Lin J, Li Y, Zhang J, Song X, Xing T, Guo T, Duan X, Zhang Y, Ruan E, Wang Q, Li B, Yang W, Yin P, Yan XX, Li S, Li XJ, Yang S
Science advances 2024 May 17;10(20):eadl2036
Science advances 2024 May 17;10(20):eadl2036
An ATP13A1-assisted topogenesis pathway for folding multi-spanning membrane proteins.
Ji J, Cui MK, Zou R, Wu MZ, Ge MX, Li J, Zhang ZR
Molecular cell 2024 May 16;84(10):1917-1931.e15
Molecular cell 2024 May 16;84(10):1917-1931.e15
CRTAC1 identified as a promising diagnosis and prognostic biomarker in lung adenocarcinoma.
Tan L, Zhang H, Ding Y, Huang Y, Sun D
Scientific reports 2024 May 16;14(1):11223
Scientific reports 2024 May 16;14(1):11223
Alnustone promotes megakaryocyte differentiation and platelet production via the interleukin-17A/interleukin-17A receptor/Src/RAC1/MEK/ERK signaling pathway.
Li Y, Lai J, Ran M, Yi T, Zhou L, Luo J, Liu X, Tang X, Huang M, Xie X, Li H, Yang Y, Zou W, Wu J
European journal of pharmacology 2024 May 15;971:176548
European journal of pharmacology 2024 May 15;971:176548
Alleviative effects of the parthenolide derivative ACT001 on insulin resistance induced by sodium propionate combined with a high-fat diet and its potential mechanisms.
Yu Q, Zuo X, Bai H, Zhang S, Luan J, Zhao Q, Zhao X, Feng X
European journal of pharmacology 2024 May 15;971:176529
European journal of pharmacology 2024 May 15;971:176529
PABPC1L Induces IDO1 to Promote Tryptophan Metabolism and Immune Suppression in Renal Cell Carcinoma.
Shu G, Chen M, Liao W, Fu L, Lin M, Gui C, Cen J, Lu J, Chen Z, Wei J, Chen W, Wang Y, Zhu J, Zhao T, Liu X, Jing J, Liu GC, Pan Y, Luo J, Zhang J
Cancer research 2024 May 15;84(10):1659-1679
Cancer research 2024 May 15;84(10):1659-1679
Deficiency of nucleosome-destabilizing factor GLYR1 dampens spermatogenesis in mice.
Cheng GP, Wang YF, Li YY, Guo SM, Li HG, Ji DM, Yi NH, Zhou LQ
Molecular and cellular endocrinology 2024 May 15;586:112194
Molecular and cellular endocrinology 2024 May 15;586:112194
Roles of AhR/CYP1s signaling pathway mediated ROS production in uremic cardiomyopathy.
Lu W, Cheng S, Xu J, Xiao Z, Yu Y, Xie Q, Fang Y, Chen R, Shen B, Xie Y, Ding X
Toxicology letters 2024 May 15;396:81-93
Toxicology letters 2024 May 15;396:81-93
Metformin induction of heat shock factor 1 activation and the mitochondrial unfolded protein response alleviate cardiac remodeling in spontaneously hypertensive rats.
Xu M, Li LP, He X, Lu XZ, Bi XY, Li Q, Xue XR
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 May 15;38(9):e23654
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 May 15;38(9):e23654
Early life stage exposure to fenbuconazole causes multigenerational cardiac developmental defects in zebrafish and potential reasons.
Zhang Y, Guo J, Tang C, Xu K, Li Z, Wang C
Environmental pollution (Barking, Essex : 1987) 2024 May 15;349:123938
Environmental pollution (Barking, Essex : 1987) 2024 May 15;349:123938
Stenotrophomonas maltophilia contributes to smoking-related emphysema through IRF1-triggered PANoptosis of alveolar epithelial cells.
Xia H, Lin J, Wang Y, Yu J, Wang H, Cheng C, Yang Y, Bian T, Wu Y, Liu Q
Environmental pollution (Barking, Essex : 1987) 2024 May 15;349:123913
Environmental pollution (Barking, Essex : 1987) 2024 May 15;349:123913
Upregulated dual oxidase 1-induced oxidative stress and caspase-1-dependent pyroptosis reflect the etiologies of heart failure.
Li YS, Xia J, Chen CY, Ren SH, He MR
BMC molecular and cell biology 2024 May 15;25(1):16
BMC molecular and cell biology 2024 May 15;25(1):16
Network pharmacology combined with lipidomics to reveal the regulatory effects and mechanisms of Kangzao granules in the hypothalamus of rats with central precocious puberty.
Jiang Y, Yang L, Chen H, Chen J, Yang L, Wang Z, Yuan X, Shan J, Lin L, Li H, Ye J
Journal of pharmaceutical and biomedical analysis 2024 May 15;242:116059
Journal of pharmaceutical and biomedical analysis 2024 May 15;242:116059
Knockdown of trem2 promotes proinflammatory microglia and inhibits glioma progression via the JAK2/STAT3 and NF-κB pathways.
Yan Y, Bai S, Han H, Dai J, Niu L, Wang H, Dong Q, Yin H, Yuan G, Pan Y
Cell communication and signaling : CCS 2024 May 15;22(1):272
Cell communication and signaling : CCS 2024 May 15;22(1):272
MiR-21-5p modulates LPS-induced acute injury in alveolar epithelial cells by targeting SLC16A10.
Zeng H, Zhou Y, Liu Z, Liu W
Scientific reports 2024 May 15;14(1):11160
Scientific reports 2024 May 15;14(1):11160
Network pharmacology-based analysis on the key mechanisms of Yiguanjian acting on chronic hepatitis.
Jiang X, Cui X, Nie R, You H, Tang Z, Liu W
Heliyon 2024 May 15;10(9):e29977
Heliyon 2024 May 15;10(9):e29977
Pseudorabies virus usurps non-muscle myosin heavy chain IIA to dampen viral DNA recognition by cGAS for antagonism of host antiviral innate immunity.
Liu Y, Qin Y, Yang B, Zheng H, Qiao S, Luo Z, Li R
Journal of virology 2024 May 14;98(5):e0048324
Journal of virology 2024 May 14;98(5):e0048324
25-Hydroxycholesterol regulates lysosome AMP kinase activation and metabolic reprogramming to educate immunosuppressive macrophages.
Xiao J, Wang S, Chen L, Ding X, Dang Y, Han M, Zheng Y, Shen H, Wu S, Wang M, Yang D, Li N, Dong C, Hu M, Su C, Li W, Hui L, Ye Y, Tang H, Wei B, Wang H
Immunity 2024 May 14;57(5):1087-1104.e7
Immunity 2024 May 14;57(5):1087-1104.e7
PLAG1 interacts with GPX4 to conquer vulnerability to sorafenib induced ferroptosis through a PVT1/miR-195-5p axis-dependent manner in hepatocellular carcinoma.
Li J, Li Y, Wang D, Liao R, Wu Z
Journal of experimental & clinical cancer research : CR 2024 May 14;43(1):143
Journal of experimental & clinical cancer research : CR 2024 May 14;43(1):143
KAP1 stabilizes MYCN mRNA and promotes neuroblastoma tumorigenicity by protecting the RNA m(6)A reader YTHDC1 protein degradation.
Yang Y, Zhang Y, Chen G, Sun B, Luo F, Gao Y, Feng H, Li Y
Journal of experimental & clinical cancer research : CR 2024 May 14;43(1):141
Journal of experimental & clinical cancer research : CR 2024 May 14;43(1):141
The Hippo pathway terminal effector TAZ/WWTR1 mediates oxaliplatin sensitivity in p53 proficient colon cancer cells.
Slaninová V, Heron-Milhavet L, Robin M, Jeanson L, Aissanou A, Kantar D, Tosi D, Bréhélin L, Gongora C, Djiane A
BMC cancer 2024 May 14;24(1):587
BMC cancer 2024 May 14;24(1):587
The crosstalk between macrophages and cancer cells potentiates pancreatic cancer cachexia.
Liu M, Ren Y, Zhou Z, Yang J, Shi X, Cai Y, Arreola AX, Luo W, Fung KM, Xu C, Nipp RD, Bronze MS, Zheng L, Li YP, Houchen CW, Zhang Y, Li M
Cancer cell 2024 May 13;42(5):885-903.e4
Cancer cell 2024 May 13;42(5):885-903.e4
Identification and verification of a novel signature that combines cuproptosis-related genes with ferroptosis-related genes in osteoarthritis using bioinformatics analysis and experimental validation.
He B, Liao Y, Tian M, Tang C, Tang Q, Ma F, Zhou W, Leng Y, Zhong D
Arthritis research & therapy 2024 May 13;26(1):100
Arthritis research & therapy 2024 May 13;26(1):100
Synergistic effect of mesenchymal stem cell-derived extracellular vesicle and miR-137 alleviates autism-like behaviors by modulating the NF-κB pathway.
Qin Q, Shan Z, Xing L, Jiang Y, Li M, Fan L, Zeng X, Ma X, Zheng D, Wang H, Wang H, Liu H, Liang S, Wu L, Liang S
Journal of translational medicine 2024 May 13;22(1):446
Journal of translational medicine 2024 May 13;22(1):446
Tumors cells with mismatch repair deficiency induce hyperactivation of pyroptosis resistant to cell membrane damage but are more sensitive to co-treatment of IFN-γ and TNF-α to PANoptosis.
Li H, Ni H, Li Y, Zhou A, Qin X, Li Y, Che L, Mo H, Qin C, Li J
Cell death discovery 2024 May 13;10(1):227
Cell death discovery 2024 May 13;10(1):227
Mesencephalic astrocyte-derived neurotrophic factor inhibits cervical cancer progression via regulating macrophage phenotype.
Huang M, Hu J, Chen Y, Xun Y, Zhang X, Cao Y
Molecular biology reports 2024 May 12;51(1):654
Molecular biology reports 2024 May 12;51(1):654
Multi-omics integration highlights the role of ubiquitination in endometriosis fibrosis.
Yang M, Jiang H, Ding X, Zhang L, Zhang H, Chen J, Li L, He X, Huang Z, Chen Q
Journal of translational medicine 2024 May 12;22(1):445
Journal of translational medicine 2024 May 12;22(1):445
Glutamine Metabolism Heterogeneity in Glioblastoma Unveils an Innovative Combination Therapy Strategy.
Fu H, Wu S, Shen H, Luo K, Huang Z, Lu N, Li Y, Lan Q, Xian Y
Journal of molecular neuroscience : MN 2024 May 10;74(2):52
Journal of molecular neuroscience : MN 2024 May 10;74(2):52
ω3-PUFA alleviates neuroinflammation by upregulating miR-107 targeting PIEZO1/NFκB p65.
Liu H, Zhou L, Yi P, Zhan F, Zhou L, Dong Y, Xiong Y, Hua F, Xu G
International immunopharmacology 2024 May 10;132:111996
International immunopharmacology 2024 May 10;132:111996
Ischemia-inhibited ferric chelate reductase 1 improves ferroptosis-mediated intestinal ischemia injury via Hippo signaling.
Liang P, Xie W, Wang X, Du Z, Zheng C, Zhao H, Wang Z, Ji Z
International immunopharmacology 2024 May 10;132:111900
International immunopharmacology 2024 May 10;132:111900
A unique circ_0067716/EIF4A3 double-negative feedback loop impacts malignant transformation of human bronchial epithelial cells induced by benzo(a)pyrene.
Zhao S, Xiao M, Li L, Zhang H, Shan M, Cui S, Zhang L, Zhang G, Wu S, Jin C, Yang J, Lu X
The Science of the total environment 2024 May 1;923:171349
The Science of the total environment 2024 May 1;923:171349
Pharmacological suppression of HHLA2 glycosylation restores anti-tumor immunity in colorectal cancer.
Zhang D, Xie J, Sun F, Xu R, Liu W, Xu J, Huang X, Zhang G
Cancer letters 2024 May 1;589:216819
Cancer letters 2024 May 1;589:216819
Cytotoxic withanolides from the stems and leaves of Physalis ixocarpa.
Xiang K, Liu Y, Zhu R, Xu Y, Sun D, Yang Y, Yan Y, Yang B, Li H, Chen L
Food chemistry 2024 May 1;439:138136
Food chemistry 2024 May 1;439:138136
Nuclear AGO2 promotes myocardial remodeling by activating ANKRD1 transcription in failing hearts.
Xie R, Yuan S, Hu G, Zhan J, Jin K, Tang Y, Fan J, Zhao Y, Wang F, Chen C, Wang DW, Li H
Molecular therapy : the journal of the American Society of Gene Therapy 2024 May 1;32(5):1578-1594
Molecular therapy : the journal of the American Society of Gene Therapy 2024 May 1;32(5):1578-1594
Hnrnpk protects against osteoarthritis through targeting WWC1 mRNA and inhibiting Hippo signaling pathway.
Zhang S, Zhang B, Liao Z, Chen Y, Guo W, Wu J, Liu H, Weng R, Su D, Chen G, Zhang Z, Li C, Long J, Xiao Y, Ma Y, Zhou T, Xu C, Su P
Molecular therapy : the journal of the American Society of Gene Therapy 2024 May 1;32(5):1461-1478
Molecular therapy : the journal of the American Society of Gene Therapy 2024 May 1;32(5):1461-1478
DDX18 Facilitates the Tumorigenesis of Lung Adenocarcinoma by Promoting Cell Cycle Progression through the Upregulation of CDK4.
Feng B, Wang X, Qiu D, Sun H, Deng J, Tan Y, Ji K, Xu S, Zhang S, Tang C
International journal of molecular sciences 2024 May 1;25(9)
International journal of molecular sciences 2024 May 1;25(9)
Eplerenone reduces lymphangiogenesis in the contralateral kidneys of UUO rats.
Hao J, Qiang P, Fan L, Xiong Y, Chang Y, Yang F, Wang X, Shimosawa T, Mu S, Xu Q
Scientific reports 2024 May 1;14(1):9976
Scientific reports 2024 May 1;14(1):9976
Kaempferol alleviates adipose tissue inflammation and insulin resistance in db/db mice by inhibiting the STING/NLRP3 signaling pathway.
Zhai H, Wang D, Wang Y, Gu H, Jv J, Yuan L, Wang C, Chen L
Endocrine connections 2024 May 1;13(5)
Endocrine connections 2024 May 1;13(5)
UMP-CMP kinase 2 inhibits ZIKV replication through activation of type I IFN signaling pathway.
Zhu Y, Tan Q, Shi Y, Li Q, Li S, Wen W, Xie H, Li B, Duan X, Chen L
Journal of medical virology 2024 Mar;96(3):e29533
Journal of medical virology 2024 Mar;96(3):e29533
microRNA profilings identify plasma biomarkers and targets associated with pediatric epilepsy patients.
Wang Q, Shi X, Li PP, Gao L, Zhou Y, Li L, Ye H, Fu X, Li P
Pediatric research 2024 Mar;95(4):996-1008
Pediatric research 2024 Mar;95(4):996-1008
Platelet rich plasma alleviates endometritis induced by lipopolysaccharide in mice via inhibiting TLR4/NF-κB signaling pathway.
Liu X, Wang Y, Wen X, Hao C, Ma J, Yan L
American journal of reproductive immunology (New York, N.Y. : 1989) 2024 Mar;91(3):e13833
American journal of reproductive immunology (New York, N.Y. : 1989) 2024 Mar;91(3):e13833
Primate Model Carrying LMNA Mutation Develops Dilated Cardiomyopathy.
Luo X, Jia H, Wang F, Mo H, Kang Y, Zhang N, Zhao L, Xu L, Yang Z, Yang Q, Chang Y, Li S, Bian N, Hua X, Cui H, Cao Y, Chu C, Zeng Y, Chen X, Chen Z, Ji W, Long C, Song J, Niu Y
JACC. Basic to translational science 2024 Mar;9(3):380-395
JACC. Basic to translational science 2024 Mar;9(3):380-395
Spinster homolog 2 reduces malignancies of glioblastoma via PTEN/PI3K/AKT pathway.
Liang W, Liu M, Su Y, Wen Y, Wang L, Shan J, Zhao J, Xie K, Wang J
IUBMB life 2024 Mar;76(3):140-160
IUBMB life 2024 Mar;76(3):140-160
Lrg1 silencing attenuates ischemia-reperfusion renal injury by regulating autophagy and apoptosis through the TGFβ1- Smad1/5 signaling pathway.
Chen J, Zhang Z, Feng L, Liu W, Wang X, Chen H, Zou H
Archives of biochemistry and biophysics 2024 Mar;753:109892
Archives of biochemistry and biophysics 2024 Mar;753:109892
Tumor-acquired somatic mutation affects conformation to abolish ABCG2-mediated drug resistance.
Gose T, Rasouli A, Dehghani-Ghahnaviyeh S, Wen PC, Wang Y, Lynch J, Fukuda Y, Shafi T, Ford RC, Tajkhorshid E, Schuetz JD
Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy 2024 Mar;73:101066
Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy 2024 Mar;73:101066
Methylation of GPRC5A promotes liver metastasis and docetaxel resistance through activating mTOR signaling pathway in triple negative breast cancer.
Ou X, Tan Y, Xie J, Yuan J, Deng X, Shao R, Song C, Cao X, Xie X, He R, Li Y, Tang H
Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy 2024 Mar;73:101063
Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy 2024 Mar;73:101063
NDRG1 overcomes resistance to immunotherapy of pancreatic ductal adenocarcinoma through inhibiting ATG9A-dependent degradation of MHC-1.
Zhang Z, Song B, Wei H, Liu Y, Zhang W, Yang Y, Sun B
Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy 2024 Mar;73:101040
Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy 2024 Mar;73:101040
Dynamics of N6-methyladenosine modification during aging and their potential roles in the degeneration of intervertebral disc.
Liu L, Sun H, Zhang Y, Liu C, Zhuang Y, Liu M, Ai X, Long D, Huang B, Li C, Zhou Y, Dong S, Feng C
JOR spine 2024 Mar;7(1):e1316
JOR spine 2024 Mar;7(1):e1316
M6PR interacts with the HA2 subunit of influenza A virus to facilitate the fusion of viral and endosomal membranes.
Hu Y, Jiang L, Wang G, Song Y, Shan Z, Wang X, Deng G, Shi J, Tian G, Zeng X, Liu L, Chen H, Li C
Science China. Life sciences 2024 Mar;67(3):579-595
Science China. Life sciences 2024 Mar;67(3):579-595
HDAC inhibitors target IRS4 to enhance anti‑AR therapy in AR‑positive triple‑negative breast cancer.
He Y, Ma Y, Zhu Y, Zhang J, Zhao S, Zhang D, Xu D, Li Y, Tong Z, Zhao W
International journal of oncology 2024 Mar;64(3)
International journal of oncology 2024 Mar;64(3)
CCL2 Knockdown Attenuates Inflammatory Response After Spinal Cord Injury Through the PI3K/Akt Signaling Pathway: Bioinformatics Analysis and Experimental Validation.
Fang S, Tang H, Li HL, Han TC, Li ZJ, Yin ZS, Chu JJ
Molecular neurobiology 2024 Mar;61(3):1433-1447
Molecular neurobiology 2024 Mar;61(3):1433-1447
Knockdown of ANGPTL4 inhibits adipogenesis of preadipocyte via autophagy.
Ling M, Qian H, Guo H
In vitro cellular & developmental biology. Animal 2024 Mar;60(3):258-265
In vitro cellular & developmental biology. Animal 2024 Mar;60(3):258-265
Bilirubin impairs neuritogenesis and synaptogenesis in NSPCs by downregulating NMDAR-CREB-BDNF signaling.
Zhang Y, Li S, Li L, Huang H, Fu Z, Hua Z
In vitro cellular & developmental biology. Animal 2024 Mar;60(2):161-171
In vitro cellular & developmental biology. Animal 2024 Mar;60(2):161-171
RNA m(5)C modification upregulates E2F1 expression in a manner dependent on YBX1 phase separation and promotes tumor progression in ovarian cancer.
Liu X, Wei Q, Yang C, Zhao H, Xu J, Mobet Y, Luo Q, Yang D, Zuo X, Chen N, Yang Y, Li L, Wang W, Yu J, Xu J, Liu T, Yi P
Experimental & molecular medicine 2024 Mar;56(3):600-615
Experimental & molecular medicine 2024 Mar;56(3):600-615
MitoQ Alleviated PM(2.5) Induced Pulmonary Epithelial Cells Injury by Inhibiting Mitochondrial-Mediated Apoptosis.
Weng AB, Deng MM, Liu XD, Wang HB, Lin Q
Iranian journal of public health 2024 Mar;53(3):614-624
Iranian journal of public health 2024 Mar;53(3):614-624
Regulator of G protein signalling 18 promotes osteocyte proliferation by activating the extracellular signal‑regulated kinase signalling pathway.
Meng Y, Qiu SQ, Wang Q, Zuo JL
International journal of molecular medicine 2024 Mar;53(3)
International journal of molecular medicine 2024 Mar;53(3)
Ferrostatin‑1 alleviates liver injury via decreasing ferroptosis following ricin toxin poisoning in rat.
Lin R, Jia Z, Chen H, Xiong H, Bian C, He X, Wei B, Fu J, Zhao M, Li J
Toxicology 2024 Mar;503:153767
Toxicology 2024 Mar;503:153767
Quercetin alleviates the toxicity of difenoconazole to the respiratory system of carp by reducing ROS accumulation and maintaining mitochondrial dynamic balance.
Ji X, Guo J, Ma Y, Zhang S, Yang Z, Li Y, Ping K, Xin Y, Dong Z
Toxicology and applied pharmacology 2024 Mar;484:116860
Toxicology and applied pharmacology 2024 Mar;484:116860
POLE2 knockdown suppresses lymphoma progression via downregulating Wnt/β-catenin signaling pathway.
Lv Z, Wu X, Lu P, Xu X, Wang J, Zhang C, Liu W, Gao Y, Lu C, Zhang Y, Kou H
Molecular and cellular biochemistry 2024 Mar;479(3):487-497
Molecular and cellular biochemistry 2024 Mar;479(3):487-497
Targeting autophagy overcomes cancer-intrinsic resistance to CAR-T immunotherapy in B-cell malignancies.
Tang L, Zhang H, Zhou F, Wei Q, Du M, Wu J, Li C, Luo W, Zhou J, Wang X, Chen Z, Zhang Y, Huang Z, Wu Z, Wen Y, Jiang H, Liao D, Kou H, Xiong W, Mei H, Hu Y
Cancer communications (London, England) 2024 Mar;44(3):408-432
Cancer communications (London, England) 2024 Mar;44(3):408-432
Pan-cancer analysis of ABCC1 as a potential prognostic and immunological biomarker.
Wang T, Rao D, Fu C, Luo Y, Lu J, Liang H, Xia L, Huang W
Translational oncology 2024 Mar;41:101882
Translational oncology 2024 Mar;41:101882
High expression of B7-H3 on monocyte/macrophages in tumor microenvironment promotes lung cancer progression by inhibiting apoptosis.
Zhang D, Huang H, Gao X, Yu G, Zhang X, Jin H, Xu R, Wang Z, Zhang G
Translational oncology 2024 Mar;41:101874
Translational oncology 2024 Mar;41:101874
Age-, sex- and proximal-distal-resolved multi-omics identifies regulators of intestinal aging in non-human primates.
Wang X, Luo Y, He S, Lu Y, Gong Y, Gao L, Mao S, Liu X, Jiang N, Pu Q, Du D, Shu Y, Hai S, Li S, Chen HN, Zhao Y, Xie D, Qi S, Lei P, Hu H, Xu H, Zhou ZG, Dong B, Zhang H, Zhang Y, Dai L
Nature aging 2024 Mar;4(3):414-433
Nature aging 2024 Mar;4(3):414-433
Phenylacetyl glutamine (PAGln) enhances cardiomyocyte death after myocardial infarction through β1 adrenergic receptor.
Xu H, Yang N, Wang BY, Zhou L, Xu LL, Chen Y, Wang DJ, Ge WH
Environmental toxicology 2024 Mar;39(3):1682-1699
Environmental toxicology 2024 Mar;39(3):1682-1699
1-Benzylimidazole attenuates the stemness of breast cancer cells through partially targeting CYP4Z1.
Qin H, Zhou Y, Liu H, Yuan Y, Guo Q, Yuan M, Xi T, Zhang Y
Environmental toxicology 2024 Mar;39(3):1505-1520
Environmental toxicology 2024 Mar;39(3):1505-1520
Ferrostatin-1 improves neurological impairment induced by ischemia/reperfusion injury in the spinal cord through ERK1/2/SP1/GPX4.
Liu S, Chen F, Han J, Wang L, Dong Y
Experimental neurology 2024 Mar;373:114659
Experimental neurology 2024 Mar;373:114659
Transcutaneous electrical acupoint stimulation attenuated neuroinflammation and oxidative stress by activating SIRT1-induced signaling pathway in MCAO/R rat models.
Tan Z, Dong F, Wu L, Xu G, Zhang F
Experimental neurology 2024 Mar;373:114658
Experimental neurology 2024 Mar;373:114658
Peroxiredoxin-1 as a molecular chaperone that regulates glutathione S-transferase P1 activity and drives mutidrug resistance in ovarian cancer cells.
Fan C, Yuan S, Zhang Y, Nie Y, Xiang L, Luo T, Xi Q, Zhang Y, Gu Z, Wang P, Zhou H
Biochemistry and biophysics reports 2024 Mar;37:101639
Biochemistry and biophysics reports 2024 Mar;37:101639
A novel antigenic epitope identified on the accessory protein NS6 of porcine deltacoronavirus.
Liu Q, Wu J, Gao N, Zhang X, Gao M, Zhang X, Guo L, Wu Y, Shi D, Shi H, Chen J, Feng L
Virus research 2024 Mar;341:199329
Virus research 2024 Mar;341:199329
Transcription factor MYB8 regulates iron deficiency stress response in Arabidopsis.
Gong Q, Zhou M, Li X, Guo Y
Plant science : an international journal of experimental plant biology 2024 Mar;340:111973
Plant science : an international journal of experimental plant biology 2024 Mar;340:111973
Structural basis for specific DNA sequence recognition by the transcription factor NFIL3.
Chen S, Lei M, Liu K, Min J
The Journal of biological chemistry 2024 Mar;300(3):105776
The Journal of biological chemistry 2024 Mar;300(3):105776
The splicing factor Prpf31 is required for hematopoietic stem and progenitor cell expansion during zebrafish embryogenesis.
Lv Y, Li J, Yu S, Zhang Y, Hu H, Sun K, Jia D, Han Y, Tu J, Huang Y, Liu X, Zhang X, Gao P, Chen X, Shaw Williams MT, Tang Z, Shu X, Liu M, Ren X
The Journal of biological chemistry 2024 Mar;300(3):105772
The Journal of biological chemistry 2024 Mar;300(3):105772
Human umbilical cord mesenchymal stem cell-derived exosomes attenuate neuroinflammation and oxidative stress through the NRF2/NF-κB/NLRP3 pathway.
Che J, Wang H, Dong J, Wu Y, Zhang H, Fu L, Zhang J
CNS neuroscience & therapeutics 2024 Mar;30(3):e14454
CNS neuroscience & therapeutics 2024 Mar;30(3):e14454
Inhibition of HDAC6 promotes microvascular endothelial cells to phagocytize myelin debris and reduces inflammatory response to accelerate the repair of spinal cord injury.
Wu C, Pan Y, Wang L, Liu M, Tu P, Chen S, Shi L, Yan D, Ma Y, Guo Y
CNS neuroscience & therapeutics 2024 Mar;30(3):e14439
CNS neuroscience & therapeutics 2024 Mar;30(3):e14439
RNA 5-Methylcytosine Regulator NSUN3 promotes tumor progression through regulating immune infiltration in head and neck squamous cell carcinoma.
Jin S, Li J, Shen Y, Wu Y, Zhang Z, Ma H
Oral diseases 2024 Mar;30(2):313-328
Oral diseases 2024 Mar;30(2):313-328
SOD2 confers anlotinib resistance via regulation of mitochondrial damage in OSCC.
Li S, Cao C, Huang Z, Tang D, Chen J, Wang A, He Q
Oral diseases 2024 Mar;30(2):281-291
Oral diseases 2024 Mar;30(2):281-291
CD24 blockade promotes anti-tumor immunity in oral squamous cell carcinoma.
Zou KL, Lan Z, Cui H, Zhao YY, Wang WM, Yu GT
Oral diseases 2024 Mar;30(2):163-171
Oral diseases 2024 Mar;30(2):163-171
Electroacupuncture Attenuates Ventilator-Induced Lung Injury by Modulating the Nrf2/HO-1 Pathway.
Luo J, Yan R, Ding L, Ning J, Chen M, Guo Y, Liu J, Chen Z, Zhou R
The Journal of surgical research 2024 Mar;295:811-819
The Journal of surgical research 2024 Mar;295:811-819
MicroRNA-194-5p/Heparin-binding EGF-like growth factor signaling mediates dexamethasone-induced activation of pseudorabies virus in rat pheochromocytoma cells.
Zhang C, Liu Y, Yang F, Liu Y, Wang N, Li Y, Liu Y, Qiu Z, Zhang L, You X, Gan L
Veterinary microbiology 2024 Mar;290:109974
Veterinary microbiology 2024 Mar;290:109974
SGLT2i improves kidney senescence by down-regulating the expression of LTBP2 in SAMP8 mice.
Zeng L, Li J, Gao F, Song Y, Wei L, Qu N, Chen S, Zhao X, Lei Z, Cao W, Chen L, Jiang H
Journal of cellular and molecular medicine 2024 Mar;28(6):e18176
Journal of cellular and molecular medicine 2024 Mar;28(6):e18176
Rhizoma Paridis saponins attenuate Gram-negative bacteria-induced inflammatory acne by binding to KEAP1 and modulating Nrf2 and MAPK pathways.
Yang Y, Wang C, Wang J, Yang L, Lv Z, An Q, Wang Y, Shao X, Wang F, Huo T, Liu J, Luo H, Quan Q
Journal of cellular and molecular medicine 2024 Mar;28(6):e18146
Journal of cellular and molecular medicine 2024 Mar;28(6):e18146
RNF125‑mediated ubiquitination of MCM6 regulates the proliferation of human liver hepatocellular carcinoma cells.
Feng X, Song D, Liu X, Liang Y, Jiang P, Wu S, Liu F
Oncology letters 2024 Mar;27(3):105
Oncology letters 2024 Mar;27(3):105
Novel MSH2 and TSC2 variants in a Chinese family with Lynch syndrome and their synergistic impact in urothelial carcinoma.
Li M, Yan X, Liu H, Miao W, Wu W, Zhao Y, Wang C, Liu H
Translational research : the journal of laboratory and clinical medicine 2024 Mar;265:26-35
Translational research : the journal of laboratory and clinical medicine 2024 Mar;265:26-35
Precision targeting of CuET overload to disrupt mitochondrial unfolded protein response by integrated liposome.
Yin X, Wu B, Yang Y, Shi J, Fu Y, Zhang H, Ye J, Sun Y, Chen C, Zhu Y, Zhang W
International journal of biological macromolecules 2024 Mar;262(Pt 1):129974
International journal of biological macromolecules 2024 Mar;262(Pt 1):129974
Prenatal EGCG consumption impacts hepatic glycogen synthesis and lipid metabolism in adult mice.
Ou K, Zhang Q, Xi F, Ni H, Lu J, Lyu X, Wang C, Li Q, Wang Q
International journal of biological macromolecules 2024 Mar;260(Pt 1):129491
International journal of biological macromolecules 2024 Mar;260(Pt 1):129491
LncRNA XXYLT1-AS2 promotes tumor progression via autophagy inhibition through ubiquitinated degradation of TFEB in hepatocellular carcinoma.
Li X, Wu Y, Wang P, Li Y, Gu J, Zhang Y, Yan S, Hu P
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 2024 Mar;26(3):698-708
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 2024 Mar;26(3):698-708
Drosophila TMEM63 and mouse TMEM63A are lysosomal mechanosensory ion channels.
Li K, Guo Y, Wang Y, Zhu R, Chen W, Cheng T, Zhang X, Jia Y, Liu T, Zhang W, Jan LY, Jan YN
Nature cell biology 2024 Mar;26(3):393-403
Nature cell biology 2024 Mar;26(3):393-403
Hyperfunction of post-synaptic density protein 95 promotes seizure response in early-stage aβ pathology.
Yook Y, Lee KY, Kim E, Lizarazo S, Yu X, Tsai NP
EMBO reports 2024 Mar;25(3):1233-1255
EMBO reports 2024 Mar;25(3):1233-1255
A lncRNA Dleu2-encoded peptide relieves autoimmunity by facilitating Smad3-mediated Treg induction.
Tang S, Zhang J, Lou F, Zhou H, Cai X, Wang Z, Sun L, Sun Y, Li X, Fan L, Li Y, Jin X, Deng S, Yin Q, Bai J, Wang H, Wang H
EMBO reports 2024 Mar;25(3):1208-1232
EMBO reports 2024 Mar;25(3):1208-1232
M1 Macrophage-Derived Exosome LncRNA PVT1 Promotes Inflammation and Pyroptosis of Vascular Smooth Muscle Cells in Abdominal Aortic Aneurysm by Inhibiting miR-186-5p and Regulating HMGB1.
Zhang J, Zhang X, Liu X, Chen H, Wang J, Ji M
Cardiovascular toxicology 2024 Mar;24(3):302-320
Cardiovascular toxicology 2024 Mar;24(3):302-320
Pharmacological induction of autophagy reduces inflammation in macrophages by degrading immunoproteasome subunits.
Zhou J, Li C, Lu M, Jiang G, Chen S, Li H, Lu K
PLoS biology 2024 Mar;22(3):e3002537
PLoS biology 2024 Mar;22(3):e3002537
SMAD7 expression in CAR-T cells improves persistence and safety for solid tumors.
Liang S, Zheng R, Zuo B, Li J, Wang Y, Han Y, Dong H, Zhao X, Zhang Y, Wang P, Meng R, Jia L, Yang A, Yan B
Cellular & molecular immunology 2024 Mar;21(3):213-226
Cellular & molecular immunology 2024 Mar;21(3):213-226
CDK12 inhibition upregulates ATG7 triggering autophagy via AKT/FOXO3 pathway and enhances anti-PD-1 efficacy in colorectal cancer.
Wu Z, Zhang W, Chen L, Wang T, Wang X, Shi H, Zhang L, Zhong M, Shi X, Mao X, Chen H, Li Q
Pharmacological research 2024 Mar;201:107097
Pharmacological research 2024 Mar;201:107097
Alpha-Emitter Radium-223 Induces STING-Dependent Pyroptosis to Trigger Robust Antitumor Immunity.
Yang M, Liu H, Lou J, Zhang J, Zuo C, Zhu M, Zhang X, Yin Y, Zhang Y, Qin S, Zhang H, Fan X, Dang Y, Cheng C, Cheng Z, Yu F
Small (Weinheim an der Bergstrasse, Germany) 2024 Mar;20(9):e2307448
Small (Weinheim an der Bergstrasse, Germany) 2024 Mar;20(9):e2307448
ALIX and TSG101 are essential for cellular entry and replication of two porcine alphacoronaviruses.
Chen X, Liang Y, Weng Z, Hu C, Peng Y, Sun Y, Gao Q, Huang Z, Tang S, Gong L, Zhang G
PLoS pathogens 2024 Mar;20(3):e1012103
PLoS pathogens 2024 Mar;20(3):e1012103
UBE3C tunes autophagy via ATG4B ubiquitination.
Sun C, Chen Y, Gu Q, Fu Y, Wang Y, Liu C, Xie H, Liao Y, Zheng Z, Liu P, Li M
Autophagy 2024 Mar;20(3):645-658
Autophagy 2024 Mar;20(3):645-658
CKLF induces microglial activation via triggering defective mitophagy and mitochondrial dysfunction.
Wang H, Ye J, Peng Y, Ma W, Chen H, Sun H, Feng Z, He W, Li G, Chu S, Zhang Z, Chen N
Autophagy 2024 Mar;20(3):590-613
Autophagy 2024 Mar;20(3):590-613
Vitamin D Receptor Activation Reduces Hepatic Inflammation via Enhancing Macrophage Autophagy in Cholestatic Mice.
Wen T, Xie J, Ma L, Hao Z, Zhang W, Wu T, Li L
The American journal of pathology 2024 Mar;194(3):369-383
The American journal of pathology 2024 Mar;194(3):369-383
A high concentrate diet inhibits forkhead box protein A2 expression, and induces oxidative stress, mitochondrial dysfunction and mitochondrial unfolded protein response in the liver of dairy cows.
Zuo RK, Wang C, Yu ZY, Shi HM, Song XK, Zhou SD, Ma NN, Chang GJ, Shen XZ
Microbial pathogenesis 2024 Mar;188:106570
Microbial pathogenesis 2024 Mar;188:106570
Chrysin alleviates DNA damage to improve disturbed immune homeostasis and pro-angiogenic environment in laser-induced choroidal neovascularization.
Wang J, Wang Z, Liu J, Zhou M, Wang H, Zhu H, Jiang M, Bo Q, Sun X
Biochimica et biophysica acta. Molecular cell research 2024 Mar;1871(3):119657
Biochimica et biophysica acta. Molecular cell research 2024 Mar;1871(3):119657
HNRNPA2B1 and HNRNPR stabilize ASCL1 in an m6A-dependent manner to promote neuroblastoma progression.
Hu T, Zeng C, Song Z, Liu Q, Chen S, Huang W, Ma Q, Li H
Biochimica et biophysica acta. Molecular basis of disease 2024 Mar;1870(3):167050
Biochimica et biophysica acta. Molecular basis of disease 2024 Mar;1870(3):167050
C/EBPα aggravates renal fibrosis in CKD through the NOX4-ROS-apoptosis pathway in tubular epithelial cells.
Xia Z, Wei Z, Li X, Liu Y, Gu X, Huang S, Zhang X, Wang W
Biochimica et biophysica acta. Molecular basis of disease 2024 Mar;1870(3):167039
Biochimica et biophysica acta. Molecular basis of disease 2024 Mar;1870(3):167039
Dual action of macrophage miR-204 confines cyclosporine A-induced atherosclerosis.
Su JH, Hong Y, Han CC, Yu J, Guan X, Zhu YM, Wang C, Ma MM, Pang RP, Ou JS, Zhou JG, Zhang ZY, Ban T, Liang SJ
British journal of pharmacology 2024 Mar;181(5):640-658
British journal of pharmacology 2024 Mar;181(5):640-658
Subtle structural alteration in indisulam switches the molecular mechanisms for the inhibitory effect on the migration of gastric cancer cells.
Hou C, Wu X, Shi R, Xing X, Tian S, Eléouët M, Qiao C, Ma J, Xu G
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Mar;172:116259
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Mar;172:116259
Identification of SLC2A1 as a predictive biomarker for survival and response to immunotherapy in lung squamous cell carcinoma.
Hao B, Dong H, Xiong R, Song C, Xu C, Li N, Geng Q
Computers in biology and medicine 2024 Mar;171:108183
Computers in biology and medicine 2024 Mar;171:108183
Rare coding variants in NOX4 link high ROS levels to psoriatic arthritis mutilans.
Wang S, Nikamo P, Laasonen L, Gudbjornsson B, Ejstrup L, Iversen L, Lindqvist U, Alm JJ, Eisfeldt J, Zheng X, Catrina SB, Taylan F, Vaz R, Ståhle M, Tapia-Paez I
EMBO molecular medicine 2024 Mar;16(3):596-615
EMBO molecular medicine 2024 Mar;16(3):596-615
mGluR7 allosteric modulator AMN082 corrects protein synthesis and pathological phenotypes in FXS.
Kumar V, Lee KY, Acharya A, Babik MS, Christian-Hinman CA, Rhodes JS, Tsai NP
EMBO molecular medicine 2024 Mar;16(3):506-522
EMBO molecular medicine 2024 Mar;16(3):506-522
Selenomethionine alleviates chronic heat stress-induced breast muscle injury and poor meat quality in broilers via relieving mitochondrial dysfunction and endoplasmic reticulum stress.
Jing J, Wang J, Xiang X, Yin S, Tang J, Wang L, Jia G, Liu G, Chen X, Tian G, Cai J, Kang B, Che L, Zhao H
Animal nutrition (Zhongguo xu mu shou yi xue hui) 2024 Mar;16:363-375
Animal nutrition (Zhongguo xu mu shou yi xue hui) 2024 Mar;16:363-375
Benvitimod Inhibits IL-4- and IL-13-Induced Tight Junction Impairment by Activating AHR/ARNT Pathway and Inhibiting STAT6 Phosphorylation in Human Keratinocytes.
Wang X, Mao D, Jia J, Zhang J
The Journal of investigative dermatology 2024 Mar;144(3):509-519.e7
The Journal of investigative dermatology 2024 Mar;144(3):509-519.e7
Proapoptotic effect of WS-299 induced by NOXA accumulation and NRF2-counterbalanced oxidative stress damage through targeting RBX1-UBE2M interaction in gastric cancers.
Ma T, Song Q, Cheng B, Guo E, Wang X, Li M, Dai M, Li S, Feng S, Yu B
Bioorganic chemistry 2024 Mar;144:107142
Bioorganic chemistry 2024 Mar;144:107142
Proteomic analysis of adult T-cell leukemia/lymphoma: A biomarker identification strategy based on preparation and in-solution digestion methods of total proteins.
Sudo H, Tonoyama Y, Ikebe E, Hasegawa H, Iha H, Ishida YI
Leukemia research 2024 Mar;138:107454
Leukemia research 2024 Mar;138:107454
LuQi formula attenuates Cardiomyocyte ferroptosis via activating Nrf2/GPX4 signaling axis in heart failure.
Cheng P, Wang X, Liu Q, Yang T, Dai E, Sha W, Qu H, Zhou H
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Mar;125:155357
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Mar;125:155357
Therapeutic potential of SHCBP1 inhibitor AZD5582 in pancreatic cancer treatment.
Ma Z, Gu Q, Dai Y, Wang Q, Shi W, Jiao Z
Cancer science 2024 Mar;115(3):820-835
Cancer science 2024 Mar;115(3):820-835
MBIP promotes ESCC metastasis by activating MAPK pathway.
Ma Y, Hua Y, Yin X, Jiao Y, Xu E, Yan T, Yang J, Zhang L
Cellular signalling 2024 Mar;115:111040
Cellular signalling 2024 Mar;115:111040
Decreased TET2/5-hmC reduces the integrity of the epidermal barrier via epigenetic dysregulation of filaggrin in psoriatic lesions.
Zhang H, Jia T, Che D, Peng B, Chu Z, Song X, Zeng W, Geng S
Journal of dermatological science 2024 Mar;113(3):103-112
Journal of dermatological science 2024 Mar;113(3):103-112
Identification of PRDX5 as A Target for The Treatment of Castration-Resistant Prostate Cancer.
Wang R, Mi Y, Ni J, Wang Y, Ding L, Ran X, Sun Q, Tan SY, Koeffler HP, Feng N, Chen YQ
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Mar;11(9):e2304939
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Mar;11(9):e2304939
Opsin-Free Activation of Bmp Receptors by a Femtosecond Laser.
Xu M, Wang H, Tian X, Li B, Wang S, Zhao X, He H
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Mar;11(10):e2308072
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Mar;11(10):e2308072
Pirin Inhibits FAS-Mediated Apoptosis to Support Colorectal Cancer Survival.
Ma H, Suleman M, Zhang F, Cao T, Wen S, Sun D, Chen L, Jiang B, Wang Y, Lin F, Wang J, Li B, Li Q
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Mar;11(10):e2301476
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Mar;11(10):e2301476
Effects of Ban Lian Zi Jin San on intestinal inflammation and barrier function of heat-stressed broilers.
Yang B, Gao Y, Xi K, Wang H, Yan M, Sun H, Lin Y, Zheng X, Li Y, Guo S, Liu C
Poultry science 2024 Mar;103(3):103425
Poultry science 2024 Mar;103(3):103425
RRM2 promotes the proliferation of chicken myoblasts, inhibits their differentiation and muscle regeneration.
Chen B, Zhang Y, Niu Y, Wang Y, Liu Y, Ji H, Han R, Tian Y, Liu X, Kang X, Li Z
Poultry science 2024 Mar;103(3):103407
Poultry science 2024 Mar;103(3):103407
Antagonizing roles of SHP1 in the pathogenesis of Helicobacter pylori infection.
Chen S, Zhao H, Tian Y, Wu Q, Zhang J, Liu S, Zhang Y, Wu Y, Li B, Chen S, Wang Z, Xiao R, Ji X
Helicobacter 2024 Mar-Apr;29(2):e13066
Helicobacter 2024 Mar-Apr;29(2):e13066
Flavokawain C inhibits proliferation and migration of liver cancer cells through FAK/PI3K/AKT signaling pathway.
Wang R, Li R, Yang H, Chen X, Wu L, Zheng X, Jin Y
Journal of cancer research and clinical oncology 2024 Mar 9;150(3):117
Journal of cancer research and clinical oncology 2024 Mar 9;150(3):117
Unveiling the Impact of ApoF Deficiency on Liver and Lipid Metabolism: Insights from Transcriptome-Wide m6A Methylome Analysis in Mice.
Shen X, Chen M, Zhang J, Lin Y, Gao X, Tu J, Chen K, Zhu A, Xu S
Genes 2024 Mar 9;15(3)
Genes 2024 Mar 9;15(3)
CD146(+)CAFs promote progression of endometrial cancer by inducing angiogenesis and vasculogenic mimicry via IL-10/JAK1/STAT3 pathway.
Yu Z, Zhang Q, Wei S, Zhang Y, Zhou T, Zhang Q, Shi R, Zinovkin D, Pranjol ZI, Zhang J, Wang H
Cell communication and signaling : CCS 2024 Mar 8;22(1):170
Cell communication and signaling : CCS 2024 Mar 8;22(1):170
TMEM160 promotes tumor immune evasion and radiotherapy resistance via PD-L1 binding in colorectal cancer.
Dai X, Wu Z, Ruan R, Chen J, Huang C, Lei W, Yao Y, Li L, Tang X, Xiong J, Feng M, Deng J
Cell communication and signaling : CCS 2024 Mar 7;22(1):168
Cell communication and signaling : CCS 2024 Mar 7;22(1):168
Macrophage-derived exosomal HMGB3 regulates silica-induced pulmonary inflammation by promoting M1 macrophage polarization and recruitment.
Qin X, Niu Z, Chen H, Hu Y
Particle and fibre toxicology 2024 Mar 7;21(1):12
Particle and fibre toxicology 2024 Mar 7;21(1):12
Inhibition of SAT1 alleviates chondrocyte inflammation and ferroptosis by repressing ALOX15 expression and activating the Nrf2 pathway.
Xu J, Ruan Z, Guo Z, Hou L, Wang G, Zheng Z, Zhang X, Liu H, Sun K, Guo F
Bone & joint research 2024 Mar 7;13(3):110-123
Bone & joint research 2024 Mar 7;13(3):110-123
An oncolytic vaccinia virus encoding hyaluronidase reshapes the extracellular matrix to enhance cancer chemotherapy and immunotherapy.
Wang S, Li Y, Xu C, Dong J, Wei J
Journal for immunotherapy of cancer 2024 Mar 7;12(3)
Journal for immunotherapy of cancer 2024 Mar 7;12(3)
ST3 beta-galactoside alpha-2,3-sialyltransferase 1 (ST3Gal1) synthesis of Siglec ligands mediates anti-tumour immunity in prostate cancer.
Garnham R, Geh D, Nelson R, Ramon-Gil E, Wilson L, Schmidt EN, Walker L, Adamson B, Buskin A, Hepburn AC, Hodgson K, Kendall H, Frame FM, Maitland N, Coffey K, Strand DW, Robson CN, Elliott DJ, Heer R, Macauley M, Munkley J, Gaughan L, Leslie J, Scott E
Communications biology 2024 Mar 6;7(1):276
Communications biology 2024 Mar 6;7(1):276
Tetramethylpyrazine alleviates hypoxia-induced proliferation, migration, and inflammatory response of fibroblast-like synoviocytes via inhibiting the HIF-1α- circCDC42BPB pathway.
Zhang YJ, Chen LF, Li X, Chen JH, Tan ZK
Advances in rheumatology (London, England) 2024 Mar 6;64(1):19
Advances in rheumatology (London, England) 2024 Mar 6;64(1):19
The RNA m(6)A reader IGF2BP3 regulates NFAT1/IRF1 axis-mediated anti-tumor activity in gastric cancer.
Ge L, Rui Y, Wang C, Wu Y, Wang H, Wang J
Cell death & disease 2024 Mar 6;15(3):192
Cell death & disease 2024 Mar 6;15(3):192
Cell-state dependent regulation of PPAR (γ) signaling by ZBTB9 in adipocytes.
Xu X, Charrier A, Congrove S, Buchner DA
bioRxiv : the preprint server for biology 2024 Mar 6;
bioRxiv : the preprint server for biology 2024 Mar 6;
Potential Impact of Hypoxic Astrocytes on the Aggravation of Depressive Symptoms in Parkinson's Disease.
Peng Y, He J, Xiang H, Xie L, She J, Cheng D, Liu B, Hu J, Qian H
Journal of molecular neuroscience : MN 2024 Mar 5;74(1):28
Journal of molecular neuroscience : MN 2024 Mar 5;74(1):28
T-2 toxin induces mitochondrial dysfunction in chondrocytes via the p53-cyclophilin D pathway.
Yu FF, Yu SY, Sun L, Zuo J, Luo KT, Wang M, Fu XL, Zhang F, Huang H, Zhou GY, Wang YJ, Ba Y
Journal of hazardous materials 2024 Mar 5;465:133090
Journal of hazardous materials 2024 Mar 5;465:133090
Parallel control of cold-triggered adipocyte thermogenesis by UCP1 and CKB.
Rahbani JF, Bunk J, Lagarde D, Samborska B, Roesler A, Xiao H, Shaw A, Kaiser Z, Braun JL, Geromella MS, Fajardo VA, Koza RA, Kazak L
Cell metabolism 2024 Mar 5;36(3):526-540.e7
Cell metabolism 2024 Mar 5;36(3):526-540.e7
Spermidine treatment: induction of autophagy but also apoptosis?
Watchon M, Wright AL, Ahel HI, Robinson KJ, Plenderleith SK, Kuriakose A, Yuan KC, Laird AS
Molecular brain 2024 Mar 5;17(1):15
Molecular brain 2024 Mar 5;17(1):15
Secretome from Magnetically Stimulated Muscle Exhibits Anticancer Potency: Novel Preconditioning Methodology Highlighting HTRA1 Action.
Tai YK, Iversen JN, Chan KKW, Fong CHH, Abdul Razar RB, Ramanan S, Yap LYJ, Yin JN, Toh SJ, Wong CJK, Koh PFA, Huang RYJ, Franco-Obregón A
Cells 2024 Mar 5;13(5)
Cells 2024 Mar 5;13(5)
Pooled CRISPR Screening Identifies P-Bodies as Repressors of Cancer Epithelial-Mesenchymal Transition.
Fang L, Zhang L, Wang M, He Y, Yang J, Huang Z, Tan Y, Fang K, Li J, Sun Z, Li Y, Tang Y, Liang W, Cui H, Zhu Q, Wu Z, Li Y, Hu Y, Chen W
Cancer research 2024 Mar 4;84(5):659-674
Cancer research 2024 Mar 4;84(5):659-674
Caspase-11/GSDMD contributes to the progression of hyperuricemic nephropathy by promoting NETs formation.
Wu F, Chen C, Lin G, Wu C, Xie J, Lin K, Dai X, Chen Z, Ye K, Yuan Y, Chen Z, Ma H, Lin Z, Xu Y
Cellular and molecular life sciences : CMLS 2024 Mar 4;81(1):114
Cellular and molecular life sciences : CMLS 2024 Mar 4;81(1):114
SARS-CoV-2 NSP2 as a Potential Delivery Vehicle for Proteins.
Zheng N, Liu S, Chen J, Xu Y, Cao W, Lin J, Lu G, Zhang G
Molecular pharmaceutics 2024 Mar 4;21(3):1149-1159
Molecular pharmaceutics 2024 Mar 4;21(3):1149-1159
Function and Mechanism of Antiviral Wasp Venom Peptide Protopolybia-MP III and Its Derivatives against HSV-1.
Sun F, Ye X, Han T, Xia J, Wu L, Zhu W, Ding L, Luo X, Qin C, Chen Z
Toxins 2024 Mar 4;16(3)
Toxins 2024 Mar 4;16(3)
NRF2 activation ameliorates blood-brain barrier injury after cerebral ischemic stroke by regulating ferroptosis and inflammation.
Fan W, Chen H, Li M, Fan X, Jiang F, Xu C, Wang Y, Wei W, Song J, Zhong D, Li G
Scientific reports 2024 Mar 4;14(1):5300
Scientific reports 2024 Mar 4;14(1):5300
NR4A1 depletion inhibits colorectal cancer progression by promoting necroptosis via the RIG-I-like receptor pathway.
Zhu J, Li J, Yang K, Chen Y, Wang J, He Y, Shen K, Wang K, Shi T, Chen W
Cancer letters 2024 Mar 31;585:216693
Cancer letters 2024 Mar 31;585:216693
Hinokitiol Inhibits Breast Cancer Cells In Vitro Stemness-Progression and Self-Renewal with Apoptosis and Autophagy Modulation via the CD44/Nanog/SOX2/Oct4 Pathway.
Chiang YF, Huang KC, Chen HY, Hamdy NM, Huang TC, Chang HY, Shieh TM, Huang YJ, Hsia SM
International journal of molecular sciences 2024 Mar 31;25(7)
International journal of molecular sciences 2024 Mar 31;25(7)
FXR Agonism with Bile Acid Mimetic Reduces Pre-Clinical Triple-Negative Breast Cancer Burden.
Joseph SC, Eugin Simon S, Bohm MS, Kim M, Pye ME, Simmons BW, Graves DG, Thomas-Gooch SM, Tanveer UA, Holt JR, Ponnusamy S, Sipe LM, Hayes DN, Cook KL, Narayanan R, Pierre JF, Makowski L
Cancers 2024 Mar 30;16(7)
Cancers 2024 Mar 30;16(7)
SIRT3 alleviates high glucose-induced chondrocyte injury through the promotion of autophagy and suppression of apoptosis in osteoarthritis progression.
Wang X, Liu Z, Deng S, Zhou J, Li X, Huang J, Chen J, Ji C, Deng Y, Hu Y
International immunopharmacology 2024 Mar 30;130:111755
International immunopharmacology 2024 Mar 30;130:111755
Zhuang-Gu-Fang intervenes vasculogenic and osteogenic coupling in GK rats through Notch1/Noggin/VEGF pathway.
Jin X, Sun Y, Bai R, Shi J, Zhai L, Jiang Y, Jiang M, He J, Li J, Wang T, Li S, Chen W
Heliyon 2024 Mar 30;10(6):e28014
Heliyon 2024 Mar 30;10(6):e28014
Novel biomarkers related to oxidative stress and immunity in chronic kidney disease.
Bai F, Wang C, Fan X, Fang L, Li L, Zhang X, Yu K, Liu L, Guo L, Yang X
Heliyon 2024 Mar 30;10(6):e27754
Heliyon 2024 Mar 30;10(6):e27754
Comprehensive analyses of m1A regulator-mediated modification patterns determining prognosis in lower-grade glioma (running title: m1A in LGG).
Lei K, Sheng Y, Luo M, Liu J, Gong C, Lv S, Tu W, Ye M, Wu M, Xiao B, Fang H, Luo H, Liu X, Long X, Zhu X, Huang K, Li J
Heliyon 2024 Mar 30;10(6):e27510
Heliyon 2024 Mar 30;10(6):e27510
Long non-coding RNA LINC01554 overexpression suppresses viability, migration, and invasion of liver cancer cells through regulating miR-148b-3p/EIF4E3.
Ren X, Wang X, Song H, Zhang C, Yuan J, He J, Li J, Wang Z
Heliyon 2024 Mar 30;10(6):e27319
Heliyon 2024 Mar 30;10(6):e27319
Dynamics of N6-methyladenosine modification during Alzheimer's disease development.
Gao S, Wang Y, Li X, Liang Y, Jin Z, Yang B, Yuan TF, Tian H, Peng B, Rao Y
Heliyon 2024 Mar 30;10(6):e26911
Heliyon 2024 Mar 30;10(6):e26911
Extracellular vesicles derived from human foreskin cells (hFS-Exo) accelerate cell migration and angiogenesis through MAPK pathway: an in vitro study.
Sağraç D, Aydın S, Kırbaş OK, Öztürkoğlu D, Şahin F
Molecular biology reports 2024 Mar 29;51(1):471
Molecular biology reports 2024 Mar 29;51(1):471
Integrative analysis of metabolism subtypes and identification of prognostic metabolism-related genes for glioblastoma.
Li J, Wei Y, Liu J, Cheng S, Zhang X, Qiu H, Li J, He C
Bioscience reports 2024 Mar 29;44(3)
Bioscience reports 2024 Mar 29;44(3)
RBP7 functions as a tumor suppressor in HR + breast cancer by inhibiting the AKT/SREBP1 pathway and reducing fatty acid.
Yu Y, Xu Z, Zhou H, Xu R, Xu J, Liu W, Wu Y, Qiu Y, Zhang G, Huang X, Chen Y
Cancer cell international 2024 Mar 29;24(1):118
Cancer cell international 2024 Mar 29;24(1):118
Adiponectin Inhibits the Progression of Obesity-Associated Papillary Thyroid Carcinoma Through Autophagy.
Li C, Zhang J, Dionigi G, Liang N, Guan H, Sun H
Endocrinology 2024 Mar 29;165(5)
Endocrinology 2024 Mar 29;165(5)
Hypermethylation of Bmp2 and Fgfr2 Promoter Regions in Bone Marrow Mesenchymal Stem Cells Leads to Bone Loss in Prematurely Aged Mice.
Wang Y, Sun L, Kan T, Xue W, Wang H, Xu P, Zhang L, Yan M, Li H, Yu Z
Aging and disease 2024 Mar 29;
Aging and disease 2024 Mar 29;
The nuclear import receptor Kapβ2 modifies neurotoxicity mediated by poly(GR) in C9orf72-linked ALS/FTD.
Cicardi ME, Kankate V, Sriramoji S, Krishnamurthy K, Markandaiah SS, Verdone BM, Girdhar A, Nelson A, Rivas LB, Boehringer A, Haeusler AR, Pasinelli P, Guo L, Trotti D
Communications biology 2024 Mar 28;7(1):376
Communications biology 2024 Mar 28;7(1):376
Propofol improves survival in a murine model of sepsis via inhibiting Rab5a-mediated intracellular trafficking of TLR4.
Zhou BW, Zhang WJ, Zhang FL, Yang X, Ding YQ, Yao ZW, Yan ZZ, Zhao BC, Chen XD, Li C, Liu KX
Journal of translational medicine 2024 Mar 28;22(1):316
Journal of translational medicine 2024 Mar 28;22(1):316
Urocortin-1 promotes colorectal cancer cell migration and proliferation and inhibits apoptosis via inhibition of the p53 signaling pathway.
Guo X, Li Y, Chen X, Sun B, Guo X
Journal of cancer research and clinical oncology 2024 Mar 28;150(3):163
Journal of cancer research and clinical oncology 2024 Mar 28;150(3):163
Fisetin Alleviates Inflammation and Oxidative Stress in Deep Vein Thrombosis via MAPK and NRF2 Signaling Pathway.
Liu H, Lu Q
International journal of molecular sciences 2024 Mar 27;25(7)
International journal of molecular sciences 2024 Mar 27;25(7)
Interleukin-2 enhancer binding factor 2 negatively regulates the replication of duck hepatitis A virus type 1 by disrupting the RNA-dependent RNA polymerase activity of 3D polymerase.
An H, Yu X, Li J, Shi F, Liu Y, Shu M, Li Z, Li X, Li W, Chen J
Veterinary research 2024 Mar 26;55(1):40
Veterinary research 2024 Mar 26;55(1):40
DDX3 regulates cancer immune surveillance via 3' UTR-mediated cell-surface expression of PD-L1.
Chen HH, Yu HI, Chang JJ, Li CW, Yang MH, Hung MC, Tarn WY
Cell reports 2024 Mar 26;43(3):113937
Cell reports 2024 Mar 26;43(3):113937
Enhancer-promoter activation by the Kaposi sarcoma-associated herpesvirus episome maintenance protein LANA.
Ye X, Guerin LN, Chen Z, Rajendren S, Dunker W, Zhao Y, Zhang R, Hodges E, Karijolich J
Cell reports 2024 Mar 26;43(3):113888
Cell reports 2024 Mar 26;43(3):113888
The Effect of Salvianolic Acid A on Tumor-Associated Macrophage Polarization and Its Mechanisms in the Tumor Microenvironment of Triple-Negative Breast Cancer.
Tang C, Jiang ST, Li CX, Jia XF, Yang WL
Molecules (Basel, Switzerland) 2024 Mar 26;29(7)
Molecules (Basel, Switzerland) 2024 Mar 26;29(7)
A decrease in integrin α5β1/FAK is associated with increased apoptosis of aortic smooth muscle cells in acute type a aortic dissection.
Xue M, Xing L, Yang Y, Shao M, Liao F, Xu F, Chen Y, Wang S, Chen B, Yao C, Gu G, Tong C
BMC cardiovascular disorders 2024 Mar 26;24(1):180
BMC cardiovascular disorders 2024 Mar 26;24(1):180
miR-101-3p-mediated role of PDZK1 in hepatocellular carcinoma progression and the underlying PI3K/Akt signaling mechanism.
Gao H, Gao Z, Liu X, Sun X, Hu Z, Song Z, Zhang C, Fei J, Wang X
Cell division 2024 Mar 26;19(1):9
Cell division 2024 Mar 26;19(1):9
Low-intensity pulsed ultrasound reduces alveolar bone resorption during orthodontic treatment via Lamin A/C-Yes-associated protein axis in stem cells.
Wu T, Zheng F, Tang HY, Li HZ, Cui XY, Ding S, Liu D, Li CY, Jiang JH, Yang RL
World journal of stem cells 2024 Mar 26;16(3):267-286
World journal of stem cells 2024 Mar 26;16(3):267-286
Piperine promotes PI3K/AKT/mTOR-mediated gut-brain autophagy to degrade α-Synuclein in Parkinson's disease rats.
Yu L, Hu X, Xu R, Zhao Y, Xiong L, Ai J, Wang X, Chen X, Ba Y, Xing Z, Guo C, Mi S, Wu X
Journal of ethnopharmacology 2024 Mar 25;322:117628
Journal of ethnopharmacology 2024 Mar 25;322:117628
Dendrobium nobile Lindl. alkaloid decreases Tau hyperphosphorylation via regulating PI3K/Akt/GSK-3β pathway in vitro and in vivo.
Huang J, Huang N, Qiu Y, Shi J
Journal of ethnopharmacology 2024 Mar 25;322:117592
Journal of ethnopharmacology 2024 Mar 25;322:117592
Diagnostic value of serum COMP and ADAMTS7 for intervertebral disc degeneration.
Ding JY, Yan X, Zhang RJ, Zhang HQ, Kang L, Jia CY, Thorne RF, Liu XY, Shen CL
European journal of medical research 2024 Mar 25;29(1):196
European journal of medical research 2024 Mar 25;29(1):196
RNA splicing regulator EIF3D regulates the tumor microenvironment through immunogene-related alternative splicing in head and neck squamous cell carcinoma.
Lu D, Mihoayi M, Ablikim Y, Arikin A
Aging 2024 Mar 25;16(7):5929-5948
Aging 2024 Mar 25;16(7):5929-5948
Loss of TMEM106B exacerbates Tau pathology and neurodegeneration in PS19 mice.
Feng T, Du H, Yang C, Wang Y, Hu F
Acta neuropathologica 2024 Mar 25;147(1):62
Acta neuropathologica 2024 Mar 25;147(1):62
Clostridium butyricum inhibits the inflammation in children with primary nephrotic syndrome by regulating Th17/Tregs balance via gut-kidney axis.
Li T, Ma X, Wang T, Tian W, Liu J, Shen W, Liu Y, Li Y, Zhang X, Ma J, Zhang X, Ma J, Wang H
BMC microbiology 2024 Mar 23;24(1):97
BMC microbiology 2024 Mar 23;24(1):97
AURKA emerges as a vulnerable target for KEAP1-deficient non-small cell lung cancer by activation of asparagine synthesis.
Deng B, Liu F, Chen N, Li X, Lei J, Chen N, Wu J, Wang X, Lu J, Fang M, Chen A, Zhang Z, He B, Yan M, Zhang Y, Wang Z, Liu Q
Cell death & disease 2024 Mar 23;15(3):233
Cell death & disease 2024 Mar 23;15(3):233
Lentiviral mediated delivery of CRISPR/Cas9 reduces intraocular pressure in a mouse model of myocilin glaucoma.
Patil SV, Kaipa BR, Ranshing S, Sundaresan Y, Millar JC, Nagarajan B, Kiehlbauch C, Zhang Q, Jain A, Searby CC, Scheetz TE, Clark AF, Sheffield VC, Zode GS
Scientific reports 2024 Mar 23;14(1):6958
Scientific reports 2024 Mar 23;14(1):6958
FBXO22 promotes glioblastoma malignant progression by mediating VHL ubiquitination and degradation.
Shen Z, Dong T, Yong H, Deng C, Chen C, Chen X, Chen M, Chu S, Zheng J, Li Z, Bai J
Cell death discovery 2024 Mar 23;10(1):151
Cell death discovery 2024 Mar 23;10(1):151
CDKL1 potentiates the antitumor efficacy of radioimmunotherapy by binding to transcription factor YBX1 and blocking PD-L1 expression in lung cancer.
Li Z, Xue H, Li J, Zheng Z, Liu Z, Dong X, Wang H, Chen J, Xu S
Journal of experimental & clinical cancer research : CR 2024 Mar 22;43(1):89
Journal of experimental & clinical cancer research : CR 2024 Mar 22;43(1):89
Human CCDC51 and yeast Mdm33 are functionally conserved mitochondrial inner membrane proteins that demarcate a subset of organelle fission events.
Edington AR, Connor OM, Marlar-Pavey M, Friedman JR
bioRxiv : the preprint server for biology 2024 Mar 22;
bioRxiv : the preprint server for biology 2024 Mar 22;
EIF2Ss, a Novel c-Myc-Correlated Gene Family, is Associated with Poor Prognosis and Immune Infiltration in Pancreatic Adenocarcinoma.
Cao Z, Jing Y, Cheng C, Wang F, Guan M, Zhang K, Jiao J, Ruan L, Chen Z
Frontiers in bioscience (Landmark edition) 2024 Mar 21;29(3):119
Frontiers in bioscience (Landmark edition) 2024 Mar 21;29(3):119
APOC1 is a prognostic biomarker associated with M2 macrophages in ovarian cancer.
Yang S, Du J, Wang W, Zhou D, Xi X
BMC cancer 2024 Mar 21;24(1):364
BMC cancer 2024 Mar 21;24(1):364
The EIF3H-HAX1 axis increases RAF-MEK-ERK signaling activity to promote colorectal cancer progression.
Jin H, Huang X, Pan Q, Ma N, Xie X, Wei Y, Yu F, Wen W, Zhang B, Zhang P, Chen X, Wang J, Liu RY, Lin J, Meng X, Lee MH
Nature communications 2024 Mar 21;15(1):2551
Nature communications 2024 Mar 21;15(1):2551
YTHDF1 Promotes Proliferation and Inhibits Apoptosis of Gastric Cancer Cells via Upregulating TCF7 mRNA Translation.
Li Y, Guo X, Liang X, Wang Z
Frontiers in bioscience (Landmark edition) 2024 Mar 20;29(3):117
Frontiers in bioscience (Landmark edition) 2024 Mar 20;29(3):117
Comprehensive analysis of scRNA-seq and bulk RNA-seq reveal the characteristics of disulfidptosis and a prognostic signature in BLCA.
Deng H, Cheng F, Cheng S
Aging 2024 Mar 20;16(6):5751-5771
Aging 2024 Mar 20;16(6):5751-5771
The E3 ligase TRIM7 suppresses the tumorigenesis of gastric cancer by targeting SLC7A11.
Chen Q, Zhang T, Zeng R, Zhang K, Li B, Zhu Z, Ma X, Zhang Y, Li L, Zhu J, Zhang G
Scientific reports 2024 Mar 20;14(1):6655
Scientific reports 2024 Mar 20;14(1):6655
Loss of FoxO1 activates an alternate mechanism of mitochondrial quality control for healthy adipose browning.
Shi L, Yang J, Tao Z, Zheng L, Bui TF, Alonso RL, Yue F, Cheng Z
Clinical science (London, England : 1979) 2024 Mar 20;138(6):371-385
Clinical science (London, England : 1979) 2024 Mar 20;138(6):371-385
Electroacupuncture improves cognitive function in a rat model of mild traumatic brain injury by regulating the SIRT-1/PGC-1α/mitochondrial pathway.
Jin B, Gao Y, Fu Y, Zhang S, Zhang K, Su Y
Chinese medical journal 2024 Mar 20;137(6):711-719
Chinese medical journal 2024 Mar 20;137(6):711-719
African swine fever virus pH240R enhances viral replication via inhibition of the type I IFN signaling pathway.
Ye G, Zhang Z, Liu X, Liu H, Chen W, Feng C, Li J, Zhou Q, Zhao D, Zhang S, Chen H, Bu Z, Huang L, Weng C
Journal of virology 2024 Mar 19;98(3):e0183423
Journal of virology 2024 Mar 19;98(3):e0183423
NS1-mediated enhancement of MVC transcription and replication promoted by KAT5/H4K12ac.
Zhang X, Guo J, Xu H, Ding S, Liu L, Chen Z, Yang J, Liu Y, Hao H, Huang F, Qiu J, Guan W, Sun Y, Liu H
Journal of virology 2024 Mar 19;98(3):e0169523
Journal of virology 2024 Mar 19;98(3):e0169523
An alpha-herpesvirus employs host HEXIM1 to promote viral transcription.
Wu Y, Sun A, Yang Q, Wang M, Tian B, Yang Q, Jia R, Chen S, Ou X, Huang J, Sun D, Zhu D, Liu M, Zhang S, Zhao X-X, He Y, Wu Z, Cheng A
Journal of virology 2024 Mar 19;98(3):e0139223
Journal of virology 2024 Mar 19;98(3):e0139223
Activation of hepatic adenosine A1 receptor ameliorates MASH via inhibiting SREBPs maturation.
Zhu W, Hong Y, Tong Z, He X, Li Y, Wang H, Gao X, Song P, Zhang X, Wu X, Tan Z, Huang W, Liu Z, Bao Y, Ma J, Zheng N, Xie C, Ke X, Zhou W, Jia W, Li M, Zhong J, Sheng L, Li H
Cell reports. Medicine 2024 Mar 19;5(3):101477
Cell reports. Medicine 2024 Mar 19;5(3):101477
Identification of host protein ENO1 (alpha-enolase) interacting with Cryptosporidium parvum sporozoite surface protein, Cpgp40.
Wang Y, Li N, Liang G, Wang L, Zhang X, Cui Z, Li X, Zhang S, Zhang L
Parasites & vectors 2024 Mar 19;17(1):146
Parasites & vectors 2024 Mar 19;17(1):146
RBBP6 maintains glioblastoma stem cells through CPSF3-dependent alternative polyadenylation.
Lin P, Chen W, Long Z, Yu J, Yang J, Xia Z, Wu Q, Min X, Tang J, Cui Y, Liu F, Wang C, Zheng J, Li W, Rich JN, Li L, Xie Q
Cell discovery 2024 Mar 19;10(1):32
Cell discovery 2024 Mar 19;10(1):32
Multiplexed DNA-PAINT Imaging of the Heterogeneity of Late Endosome/Lysosome Protein Composition.
Bond C, Hugelier S, Xing J, Sorokina EM, Lakadamyali M
bioRxiv : the preprint server for biology 2024 Mar 19;
bioRxiv : the preprint server for biology 2024 Mar 19;
PDCL3 is a prognostic biomarker associated with immune infiltration in hepatocellular carcinoma.
Jin W, Wang G, Dong M, Wang X
European journal of medical research 2024 Mar 17;29(1):177
European journal of medical research 2024 Mar 17;29(1):177
Deubiquitinase PSMD7 facilitates pancreatic cancer progression through activating Nocth1 pathway via modifying SOX2 degradation.
Luo C, Yu Y, Zhu J, Chen L, Li D, Peng X, Liu Z, Li Q, Cao Q, Huang K, Yuan R
Cell & bioscience 2024 Mar 17;14(1):35
Cell & bioscience 2024 Mar 17;14(1):35
Palmatine alleviates cardiac fibrosis by inhibiting fibroblast activation through the STAT3 pathway.
Lin S, Zhang S, Zhan A, Feng J, Yang Q, Li T, Liu Z, Mo Q, Fan H, Wang K, Wang L
European journal of pharmacology 2024 Mar 15;967:176395
European journal of pharmacology 2024 Mar 15;967:176395
Cardiac injury activates STING signaling via upregulating SIRT6 in macrophages after myocardial infarction.
Kong W, Chen J, Ruan X, Xu X, Li X, Bao M, Shao Y, Bian X, Li R, Jiang Q, Zhang Y, Li Z, Yan F, Ye J
Life sciences 2024 Mar 15;341:122474
Life sciences 2024 Mar 15;341:122474
Mapping the substrate landscape of protein phosphatase 2A catalytic subunit PPP2CA.
Brewer A, Sathe G, Pflug BE, Clarke RG, Macartney TJ, Sapkota GP
iScience 2024 Mar 15;27(3):109302
iScience 2024 Mar 15;27(3):109302
TET2 regulation of alcoholic fatty liver via Srebp1 mRNA in paraspeckles.
Li Q, Pan Y, Zhang J, Hu B, Qin D, Liu S, Chen N, Zhang L
iScience 2024 Mar 15;27(3):109278
iScience 2024 Mar 15;27(3):109278
Glioblastoma stem cell-derived exosomal miR-374b-3p promotes tumor angiogenesis and progression through inducing M2 macrophages polarization.
Huang S, Zhang P, Yin N, Xu Z, Liu X, Wu A, Zhang X, Li Z, Zhang Z, Zhong T, Liu L, Shi Y, Dong J
iScience 2024 Mar 15;27(3):109270
iScience 2024 Mar 15;27(3):109270
DUB3 is a MAGEA3 deubiquitinase and a potential therapeutic target in hepatocellular carcinoma.
Chen Y, Gao F, He Y, Liu M, Quan Y, Zhang P
iScience 2024 Mar 15;27(3):109181
iScience 2024 Mar 15;27(3):109181
Microglia-endothelial cross-talk regulates diabetes-induced retinal vascular dysfunction through remodeling inflammatory microenvironment.
Ben S, Ma Y, Bai Y, Zhang Q, Zhao Y, Xia J, Yao M
iScience 2024 Mar 15;27(3):109145
iScience 2024 Mar 15;27(3):109145
YAP-mediated GPER signaling impedes proliferation and survival of prostate epithelium in benign prostatic hyperplasia.
Liu Z, Li S, Chen S, Sheng J, Li Z, Lv T, Yu W, Fan Y, Wang J, Liu W, Hu S, Jin J
iScience 2024 Mar 15;27(3):109125
iScience 2024 Mar 15;27(3):109125
Basic-helix-loop-helix family member e41 suppresses osteoclastogenesis and abnormal bone resorption disease via NFATc1.
Zhang Y, Li X, Lang J, Li W, Huang D, Sun W, Yang L, Li W, Wang Y, Zhang L
iScience 2024 Mar 15;27(3):109059
iScience 2024 Mar 15;27(3):109059
Discovery of novel osthole derivatives exerting anti-inflammatory effect on DSS-induced ulcerative colitis and LPS-induced acute lung injury in mice.
Zhou Y, Du Z, Wu Q, Guo M, Chen Z, Sun C, Li X, Zou Y, Zheng Z, Chen P, Cho WJ, Cho YC, Chattipakorn N, Wang Y, Liang G, Tang Q
European journal of medicinal chemistry 2024 Mar 15;268:116252
European journal of medicinal chemistry 2024 Mar 15;268:116252
Identification of a ferritinophagy inducer via sinomenine modification for the treatment of colorectal cancer.
Zhu L, Chen C, Cai Y, Li Y, Gong L, Zhu T, Kong L, Luo J
European journal of medicinal chemistry 2024 Mar 15;268:116250
European journal of medicinal chemistry 2024 Mar 15;268:116250
Pitavastatin induces autophagy-dependent ferroptosis in MDA-MB-231 cells via the mevalonate pathway.
Tang WJ, Xu D, Liang MX, Wo GQ, Chen WQ, Tang JH, Zhang W
Heliyon 2024 Mar 15;10(5):e27084
Heliyon 2024 Mar 15;10(5):e27084
Cyclin-dependent kinase inhibitor 1A inhibits pyroptosis to enhance human lung adenocarcinoma cell radioresistance by promoting DNA repair.
Li J, Liu T, Tang N, Lin S, Zhang F, Yuan W, Zhang T, Deng SH, Wu DM, Xu Y
Heliyon 2024 Mar 15;10(5):e26975
Heliyon 2024 Mar 15;10(5):e26975
Modulation of GPER1 alleviates early brain injury via inhibition of A1 reactive astrocytes activation after intracerebral hemorrhage in mice.
Mao J, Guo Y, Li H, Ge H, Zhang C, Feng H, Zhong J, Hu R, Wang X
Heliyon 2024 Mar 15;10(5):e26909
Heliyon 2024 Mar 15;10(5):e26909
PEBP4 deficiency aggravates LPS-induced acute lung injury and alveolar fluid clearance impairment via modulating PI3K/AKT signaling pathway.
Shi QQ, Huang YH, Li YF, Zhen SY, Li YH, Huang JY, Wang JY, Zhou XY
Cellular and molecular life sciences : CMLS 2024 Mar 13;81(1):133
Cellular and molecular life sciences : CMLS 2024 Mar 13;81(1):133
Characterization of a novel heterozygous frameshift variant in NDP gene that causes familial exudative vitreoretinopathy in female patients.
Yang M, Peng L, Lv L, Dai E, He Y, Zhao R, Li S
Molecular genetics and genomics : MGG 2024 Mar 13;299(1):32
Molecular genetics and genomics : MGG 2024 Mar 13;299(1):32
NSP6 inhibits the production of ACE2-containing exosomes to promote SARS-CoV-2 infectivity.
Lv X, Chen R, Liang T, Peng H, Fang Q, Xiao S, Liu S, Hu M, Yu F, Cao L, Zhang Y, Pan T, Xi Z, Ding Y, Feng L, Zeng T, Huang W, Zhang H, Ma X
mBio 2024 Mar 13;15(3):e0335823
mBio 2024 Mar 13;15(3):e0335823
GALNT2 targeted by miR-139-5p promotes proliferation of clear cell renal cell carcinoma via inhibition of LATS2 activation.
Yi H, Liu L, Zhang J, Guo K, Cao Y, Sun P, Wang H
Discover oncology 2024 Mar 13;15(1):73
Discover oncology 2024 Mar 13;15(1):73
Interferon-γ in the tumor microenvironment promotes the expression of B7H4 in colorectal cancer cells, thereby inhibiting cytotoxic T cells.
Jing ZL, Liu GL, Zhou N, Xu DY, Feng N, Lei Y, Ma LL, Tang MS, Tong GH, Tang N, Deng YJ
Scientific reports 2024 Mar 13;14(1):6053
Scientific reports 2024 Mar 13;14(1):6053
Investigating the therapeutic effects and mechanisms of Carthamus tinctorius L.-derived nanovesicles in atherosclerosis treatment.
Yang R, Lin F, Wang W, Dai G, Ke X, Wu G
Cell communication and signaling : CCS 2024 Mar 12;22(1):178
Cell communication and signaling : CCS 2024 Mar 12;22(1):178
Neutrophil Nanodecoys Inhibit Tumor Metastasis by Blocking the Interaction between Tumor Cells and Neutrophils.
Zeng W, Wang Y, Zhang Q, Hu C, Li J, Feng J, Hu C, Su Y, Lou J, Long L, Zhou X
ACS nano 2024 Mar 12;18(10):7363-7378
ACS nano 2024 Mar 12;18(10):7363-7378
Single-cell RNA-seq reveals keratinocyte and fibroblast heterogeneity and their crosstalk via epithelial-mesenchymal transition in psoriasis.
Guo D, Li X, Wang J, Liu X, Wang Y, Huang S, Dang N
Cell death & disease 2024 Mar 12;15(3):207
Cell death & disease 2024 Mar 12;15(3):207
Linker Histone H1.4 Inhibits the Growth, Migration and EMT Process of Non-Small Cell Lung Cancer by Regulating ERK1/2 Expression.
Chen Q, Yang M, Duan X, Zhang J, Shi F, Chen R, Li Y
Biochemical genetics 2024 Mar 12;
Biochemical genetics 2024 Mar 12;
PUF partner interactions at a conserved interface shape the RNA-binding landscape and cell fate in Caenorhabditis elegans.
Carrick BH, Crittenden SL, Chen F, Linsley M, Woodworth J, Kroll-Conner P, Ferdous AS, Keleş S, Wickens M, Kimble J
Developmental cell 2024 Mar 11;59(5):661-675.e7
Developmental cell 2024 Mar 11;59(5):661-675.e7
FA2H controls cool temperature sensing through modifying membrane sphingolipids in Drosophila.
Li Q, Chen L, Yang L, Zhang P
Current biology : CB 2024 Mar 11;34(5):997-1009.e6
Current biology : CB 2024 Mar 11;34(5):997-1009.e6
Parathyroid hormone-related protein as a potential prostate cancer biomarker: Promoting prostate cancer progression through upregulation of c-Met expression.
Zhao Y, Fu ZY, Feng HY, Peng YH, Yin ZX, Cao JY, Pei CS
Biomolecules & biomedicine 2024 Mar 11;24(2):374-386
Biomolecules & biomedicine 2024 Mar 11;24(2):374-386
Mefloquine enhances the efficacy of anti-PD-1 immunotherapy via IFN-γ-STAT1-IRF1-LPCAT3-induced ferroptosis in tumors.
Tao Q, Liu N, Wu J, Chen J, Chen X, Peng C
Journal for immunotherapy of cancer 2024 Mar 11;12(3)
Journal for immunotherapy of cancer 2024 Mar 11;12(3)
Cluster of Differentiation-44-Targeting Prussian Blue Nanoparticles Onloaded with Colchicine for Atherosclerotic Plaque Regression in a Mice Model.
Zhu Y, Fang Y, Wang Y, Han D, Liu J, Tian L, Xu M, Wang Y, Cao F
ACS biomaterials science & engineering 2024 Mar 11;10(3):1530-1543
ACS biomaterials science & engineering 2024 Mar 11;10(3):1530-1543
Endothelium-targeted Ddx24 conditional knockout exacerbates ConA-induced hepatitis in mice due to vascular hyper-permeability.
Gan H, Cai J, Li L, Zheng X, Yan L, Hu X, Zhao N, Li B, He J, Wang D, Pang P
International immunopharmacology 2024 Mar 10;129:111618
International immunopharmacology 2024 Mar 10;129:111618
Scleroglucan protects the intestine from irradiation-induced injury by targeting the IL-17 signaling pathway.
Huang D, Wang Y, Zhai X, Shen Q, Zhang L, Fang D, Fang L, Zhang J, Ma Y, Chu C, Liu G, Cheng Y, Liu C, Du J, Cai J
International immunopharmacology 2024 Mar 10;129:111614
International immunopharmacology 2024 Mar 10;129:111614
Effect of lipopolysaccharide on TAK1-mediated hepatocyte PANoptosis through Toll-like receptor 4 during acute liver failure.
Li W, Zhang W, Zhang D, Shi C, Wang Y
International immunopharmacology 2024 Mar 10;129:111612
International immunopharmacology 2024 Mar 10;129:111612
IL-35 ameliorates lipopolysaccharide-induced endothelial dysfunction by inhibiting endothelial-to-mesenchymal transition.
Feng J, Li K, Xie F, Han L, Wu Y
International immunopharmacology 2024 Mar 10;129:111567
International immunopharmacology 2024 Mar 10;129:111567
Clinical and functional characterization of rare compound heterozygous mutations in the SERPINC1 gene causing severe thrombophilia.
Zhang K, Zhang H, Yu D, Pan J, Wang M, Xie H
Gene 2024 Mar 1;897:148085
Gene 2024 Mar 1;897:148085
KIAA1429 facilitates metastasis via m6A-YTHDC1-dependent RND3 down-regulation in hepatocellular carcinoma cells.
Shan M, Liu D, Sun L, Yang M, He M, Zhang Y, Xiang L, Lu L, He H, Niu D, Chen L, Li S, Chen A, He F, Wang Y, Lian J
Cancer letters 2024 Mar 1;584:216598
Cancer letters 2024 Mar 1;584:216598
Echinacoside alleviates glucocorticoid induce osteonecrosis of femoral head in rats through PI3K/AKT/FOXO1 pathway.
Huang LK, Zeng XS, Jiang ZW, Peng H, Sun F
Chemico-biological interactions 2024 Mar 1;391:110893
Chemico-biological interactions 2024 Mar 1;391:110893
Structural characterization of an inulin neoseries-type fructan from Ophiopogonis Radix and the therapeutic effect on liver fibrosis in vivo.
Liu W, Zhang L, Wei X, Xu Y, Fang Q, Qi S, Chen J, Wang C, Wang S, Qin L, Liu P, Wu J
Carbohydrate polymers 2024 Mar 1;327:121659
Carbohydrate polymers 2024 Mar 1;327:121659
The role of DRP1 mediated mitophagy in HT22 cells apoptosis induced by silica nanoparticles.
Tian T, Pang H, Li X, Ma K, Liu T, Li J, Luo Z, Li M, Hou Q, Hao H, Dong J, Du H, Liu X, Sun Z, Zhao C, Song X, Jin M
Ecotoxicology and environmental safety 2024 Mar 1;272:116050
Ecotoxicology and environmental safety 2024 Mar 1;272:116050
Expression levels of key immune indicators and immune checkpoints in manganese-exposed rats.
Qi Y, Si H, Jin X, Guo Y, Xia J, He J, Deng X, Deng M, Yao W, Hao C
Ecotoxicology and environmental safety 2024 Mar 1;272:116029
Ecotoxicology and environmental safety 2024 Mar 1;272:116029
Comprehensive Atlas of Alternative Splicing Reveals NSRP1 Promoting Adipogenesis through CCDC18.
Liu L, Wang W, Liu W, Li X, Yi G, Adetula AA, Huang H, Tang Z
International journal of molecular sciences 2024 Mar 1;25(5)
International journal of molecular sciences 2024 Mar 1;25(5)
Promoting collateral formation in type 2 diabetes mellitus using ultra-small nanodots with autophagy activation and ROS scavenging.
Wang Y, Li F, Mao L, Liu Y, Chen S, Liu J, Huang K, Chen Q, Wu J, Lu L, Zheng Y, Shen W, Ying T, Dai Y, Shen Y
Journal of nanobiotechnology 2024 Mar 1;22(1):85
Journal of nanobiotechnology 2024 Mar 1;22(1):85
FTO demethylates regulates cell-cycle progression by controlling CCND1 expression in luteinizing goat granulosa cells.
Li D, Zhou L, Liu Z, Zhang Z, Mao W, Shi W, Zhu M, Wang F, Wan Y
Theriogenology 2024 Mar 1;216:20-29
Theriogenology 2024 Mar 1;216:20-29
Down-regulating nuclear factor of activated T cells 1 alleviates cognitive deficits in a mouse model of sepsis-associated encephalopathy, possibly by stimulating hippocampal neurogenesis.
Guo Y, Feng Y, Jiang F, Hu L, Shan T, Li H, Liao H, Bao H, Shi H, Si Y
Brain research 2024 Mar 1;1826:148731
Brain research 2024 Mar 1;1826:148731
GLA Mutations Suppress Autophagy and Stimulate Lysosome Generation in Fabry Disease.
Li P, Xi Y, Zhang Y, Samad A, Lan W, Wu Y, Zhao J, Chen G, Wu C, Xiong Q
Cells 2024 Mar 1;13(5)
Cells 2024 Mar 1;13(5)
TRIM28-Mediated Excessive Oxidative Stress Induces Cellular Senescence in Granulosa Cells and Contributes to Premature Ovarian Insufficiency In Vitro and In Vivo.
Zhou C, Li D, He J, Luo T, Liu Y, Xue Y, Huang J, Zheng L, Li J
Antioxidants (Basel, Switzerland) 2024 Mar 1;13(3)
Antioxidants (Basel, Switzerland) 2024 Mar 1;13(3)
Molecular characterization of the ER stress-inducible factor CRELD2.
Hinaga S, Kandeel M, Oh-Hashi K
Cell biochemistry and biophysics 2024 Jun;82(2):1463-1475
Cell biochemistry and biophysics 2024 Jun;82(2):1463-1475
The α-1 Adrenergic Receptor Antagonist Doxazosin Attenuates Liver Fibrosis by Alleviating Sinusoidal Capillarization and Liver Angiogenesis.
Xiu AY, Ding Q, Zhu CP, Zhang CQ
Advanced biology 2024 Jun;8(6):e2300513
Advanced biology 2024 Jun;8(6):e2300513
Inhibition of HDAC6 with CAY10603 alleviates acute and chronic kidney injury by suppressing the ATF6 branch of UPR.
Kan S, Hou Q, Yang R, Yang F, Zhang M, Liu Z, Jiang S
Archives of biochemistry and biophysics 2024 Jun;756:110009
Archives of biochemistry and biophysics 2024 Jun;756:110009
Linc00673-V3 positively regulates autophagy by promoting Smad3-mediated LC3B transcription in NSCLC.
Ni H, Tang S, Lu G, Niu Y, Xu J, Zhang H, Hu J, Shen HM, Wu Y, Xia D
Life science alliance 2024 Jun;7(6)
Life science alliance 2024 Jun;7(6)
Apigetrin alleviates intervertebral disk degeneration by regulating nucleus pulposus cell autophagy.
Xu T, Zhao H, Li J, Fang X, Wu H, Hu W
JOR spine 2024 Jun;7(2):e1325
JOR spine 2024 Jun;7(2):e1325
Dietary Flavonoid Quercetin Supplement Promotes Antiviral Innate Responses Against Vesicular Stomatitis Virus Infection by Reshaping the Bacteriome and Host Metabolome in Mice.
Li T, Zhu J, Yu Q, Zhu Y, Wu C, Zheng X, Chen N, Pei P, Yang K, Wang K, Hu L
Molecular nutrition & food research 2024 Jun;68(11):e2300898
Molecular nutrition & food research 2024 Jun;68(11):e2300898
CircUTRN24/miR-483-3p/IGF-1 Regulates Autophagy Mediated Liver Fibrosis in Biliary Atresia.
Liu D, Wu Z, Gao J, Mei Q, Zhang X, Wang B
Molecular biotechnology 2024 Jun;66(6):1424-1433
Molecular biotechnology 2024 Jun;66(6):1424-1433
Long non‑coding RNA lung cancer‑associated transcript 1 regulates ferroptosis via microRNA‑34a‑5p‑mediated GTP cyclohydrolase 1 downregulation in lung cancer cells.
Tai F, Zhai R, Ding K, Zhang Y, Yang H, Li H, Wang Q, Cao Z, Ge C, Fu H, Xiao F, Zheng X
International journal of oncology 2024 Jun;64(6)
International journal of oncology 2024 Jun;64(6)
ROS-dependent S-palmitoylation activates cleaved and intact gasdermin D.
Du G, Healy LB, David L, Walker C, El-Baba TJ, Lutomski CA, Goh B, Gu B, Pi X, Devant P, Fontana P, Dong Y, Ma X, Miao R, Balasubramanian A, Puthenveetil R, Banerjee A, Luo HR, Kagan JC, Oh SF, Robinson CV, Lieberman J, Wu H
Nature 2024 Jun;630(8016):437-446
Nature 2024 Jun;630(8016):437-446
The RNA-binding protein sorbin and SH3 domain-containing 2 are transcriptionally regulated by specificity protein 1 and function as tumor suppressors in bladder cancer by stabilizing tissue factor pathway inhibitor.
Wang B, Fan X, Wang L, Wei X
Molecular carcinogenesis 2024 Jun;63(6):1174-1187
Molecular carcinogenesis 2024 Jun;63(6):1174-1187
BATF promotes extramedullary infiltration through TGF-β1/Smad/MMPs axis in acute myeloid leukemia.
Zhang R, Miao J, Zhai M, Liu R, Li F, Xu X, Huang L, Wang T, Yang R, Yang R, Wang Y, He A, Wang J
Molecular carcinogenesis 2024 Jun;63(6):1146-1159
Molecular carcinogenesis 2024 Jun;63(6):1146-1159
Effect of CHRDL1 on angiogenesis and metastasis of colorectal cancer cells via TGF-β/VEGF pathway.
Li J, Jiang Z, He J, Yang K, Chen J, Deng Q, Li X, Wu F, Xu S, Jiang Z
Molecular carcinogenesis 2024 Jun;63(6):1092-1105
Molecular carcinogenesis 2024 Jun;63(6):1092-1105
Linc00239 Promotes Colorectal Cancer Development via MicroRNA-182-5p/Metadherin Axis.
Guo J, Xie T, Zhang S
Biochemical genetics 2024 Jun;62(3):1727-1741
Biochemical genetics 2024 Jun;62(3):1727-1741
Colorectal cancer cells with stably expressed SIRT3 demonstrate proliferating retardation by Wnt/β-catenin cascade inactivation.
Li T, Fan L, Jia Y, Xu C, Guo W, Wang Y, Li Y
Clinical and experimental pharmacology & physiology 2024 Jun;51(6):e13856
Clinical and experimental pharmacology & physiology 2024 Jun;51(6):e13856
Cysteine and glycine-rich protein 2 is crucial for maintaining the malignant phenotypes of gliomas through its action on Notch signalling cascade.
Liu L, Li F, Zhang L, Cheng Y, Wu L, Tie R, Jiang X, Gao W, Liu B, Wei Y, Chang P, Xu J, Zhao H, Zhang L
Toxicology and applied pharmacology 2024 Jun;487:116969
Toxicology and applied pharmacology 2024 Jun;487:116969
IL-22 promotes occludin expression by activating autophagy and treats ulcerative colitis.
Nong H, Yuan H, Lin Y, Chen S, Li Y, Luo Z, Yang W, Zhang T, Chen Y
Molecular and cellular biochemistry 2024 Jun;479(6):1443-1450
Molecular and cellular biochemistry 2024 Jun;479(6):1443-1450
ITGB2-ICAM1 axis promotes liver metastasis in BAP1-mutated uveal melanoma with retained hypoxia and ECM signatures.
Li J, Cao D, Jiang L, Zheng Y, Shao S, Zhuang A, Xiang D
Cellular oncology (Dordrecht, Netherlands) 2024 Jun;47(3):951-965
Cellular oncology (Dordrecht, Netherlands) 2024 Jun;47(3):951-965
CSGALNACT2 restricts ovarian cancer migration and invasion by modulating MAPK/ERK pathway through DUSP1.
Ma M, Wang C, Wu M, Gu S, Yang J, Zhang Y, Cheng S, Xu S, Zhang M, Wu Y, Zhao Y, Tian X, Voon DC, Takahashi C, Sheng J, Wang Y
Cellular oncology (Dordrecht, Netherlands) 2024 Jun;47(3):897-915
Cellular oncology (Dordrecht, Netherlands) 2024 Jun;47(3):897-915
Stiffened tumor microenvironment enhances perineural invasion in breast cancer via integrin signaling.
Han B, Guan X, Ma M, Liang B, Ren L, Liu Y, Du Y, Jiang SH, Song D
Cellular oncology (Dordrecht, Netherlands) 2024 Jun;47(3):867-882
Cellular oncology (Dordrecht, Netherlands) 2024 Jun;47(3):867-882
TRPV1 inhibition suppresses non-small cell lung cancer progression by inhibiting tumour growth and enhancing the immune response.
Wang Y, Zhang Y, Ouyang J, Yi H, Wang S, Liu D, Dai Y, Song K, Pei W, Hong Z, Chen L, Zhang W, Liu Z, Mcleod HL, He Y
Cellular oncology (Dordrecht, Netherlands) 2024 Jun;47(3):779-791
Cellular oncology (Dordrecht, Netherlands) 2024 Jun;47(3):779-791
PHPB ameliorates memory deficits and reduces oxidative injury in Alzheimer's disease mouse model by activating Nrf2 signaling pathway.
Shang NY, Huang LJ, Lan JQ, Kang YY, Tang JS, Wang HY, Li XN, Sun Z, Chen QY, Liu MY, Wen ZP, Feng XH, Wu L, Peng Y
Acta pharmacologica Sinica 2024 Jun;45(6):1142-1159
Acta pharmacologica Sinica 2024 Jun;45(6):1142-1159
Ubiquitin-specific protease 54 regulates GLUT1-mediated aerobic glycolysis to inhibit lung adenocarcinoma progression by modifying p53 degradation.
Chen L, Zhang L, He H, Shao F, Yu Z, Gao Y, He J
Oncogene 2024 Jun;43(26):2025-2037
Oncogene 2024 Jun;43(26):2025-2037
Electroacupuncture attenuates cerebral ischemia/reperfusion injury by regulating oxidative stress, neuronal death and neuroinflammation via stimulation of PPAR-γ.
Cheng N, Cheng X, Tan F, Liang Y, Xu L, Wang J, Tan J
Acupuncture in medicine : journal of the British Medical Acupuncture Society 2024 Jun;42(3):133-145
Acupuncture in medicine : journal of the British Medical Acupuncture Society 2024 Jun;42(3):133-145
Cold atmospheric plasma can effectively disinfect SARS-CoV-2 in the wastewater.
Qin H, Qiu H, Liu K, Hong B, Liu Y, Li C, Li M, An X, Song L, Robert E, Tong Y, Fan H, Wang R
Exploration (Beijing, China) 2024 Jun;4(3):20230012
Exploration (Beijing, China) 2024 Jun;4(3):20230012
Licochalcone A alleviates ferroptosis in doxorubicin-induced cardiotoxicity via the PI3K/AKT/MDM2/p53 pathway.
Chen G, Luo S, Guo H, Lin J, Xu S
Naunyn-Schmiedeberg's archives of pharmacology 2024 Jun;397(6):4247-4262
Naunyn-Schmiedeberg's archives of pharmacology 2024 Jun;397(6):4247-4262
Preventive effects of Ramelteon on bleomycin-induced pulmonary fibrosis in mice.
Zhang L, Cheng T, Chen W, Zhong C, Li M, Xie Y, Deng Q, Wang H, Yang Z, Ju J, Liang H
Naunyn-Schmiedeberg's archives of pharmacology 2024 Jun;397(6):4153-4163
Naunyn-Schmiedeberg's archives of pharmacology 2024 Jun;397(6):4153-4163
Down-regulation of O-GlcNAcylation alleviates insulin signaling pathway impairment following arsenic exposure via suppressing the AMPK/mTOR-autophagy pathway.
Zhang W, Zeng S, Huang J, Tian X, Wu J, Guo L, Liang Y
Toxicology letters 2024 Jun;397:67-78
Toxicology letters 2024 Jun;397:67-78
Arsenic exposure induced renal fibrosis via regulation of mitochondrial dynamics and the NLRP3-TGF-β1/SMAD signaling pathway.
Ren M, Li J, Xu Z, Nan B, Gao H, Wang H, Lin Y, Shen H
Environmental toxicology 2024 Jun;39(6):3679-3693
Environmental toxicology 2024 Jun;39(6):3679-3693
Vaccine Targeting Alpha 1D-Adrenergic Receptor Improved Metabolic Syndrome in Mice.
Li X, Ma W, Zhou Y, Li C, Shi D, Kuang W, Wu J, Liao Y, Qiu Z, Zhou Z
Cardiovascular drugs and therapy 2024 Jun;38(3):539-554
Cardiovascular drugs and therapy 2024 Jun;38(3):539-554
LAMC1 attenuates neuronal apoptosis via FAK/PI3K/AKT signaling pathway after subarachnoid hemorrhage.
Wu Q, Yuan K, Yao Y, Yao J, Shao J, Meng Y, Wu P, Shi H
Experimental neurology 2024 Jun;376:114776
Experimental neurology 2024 Jun;376:114776
BMSC-Exosomes attenuate ALP dysfunction by restoring lysosomal function via the mTOR/TFEB Axis to reduce cerebral ischemia-reperfusion injury.
Liu H, Li C, Zhang X, Chen H, Zhang Q, Zeng Y, Zheng S, Zou J, Zhao Y, Zheng X, Huang G, Zeng Q
Experimental neurology 2024 Jun;376:114726
Experimental neurology 2024 Jun;376:114726
Bioinspired engineering ADSC nanovesicles thermosensitive hydrogel enhance autophagy of dermal papilla cells for androgenetic alopecia treatment.
Xiong J, Liu Z, Jia L, Sun Y, Guo R, Xi T, Li Z, Wu M, Jiang H, Li Y
Bioactive materials 2024 Jun;36:112-125
Bioactive materials 2024 Jun;36:112-125
Myricanol attenuates sepsis-induced inflammatory responses by nuclear factor erythroid 2-related factor 2 signaling and nuclear factor kappa B/mitogen-activated protein kinase pathway via upregulating Sirtuin 1.
Liu K, Yang L, Wang P, Zhu J, Li F, Peng J, Huang K, Liang M
Inflammopharmacology 2024 Jun;32(3):1887-1901
Inflammopharmacology 2024 Jun;32(3):1887-1901
Heparanase interacting BCLAF1 to promote the development and drug resistance of ICC through the PERK/eIF2α pathway.
Yuan F, Zhou H, Liu C, Wang Y, Quan J, Liu J, Li H, von Itzstein M, Yu X
Cancer gene therapy 2024 Jun;31(6):904-916
Cancer gene therapy 2024 Jun;31(6):904-916
cGAS suppresses hepatocellular carcinoma independent of its cGAMP synthase activity.
Ma D, Yang M, Sun C, Cui X, Xiong G, Wang Q, Jing W, Chen H, Lv X, Liu S, Li T, Zhao Y, Han L
Cell death and differentiation 2024 Jun;31(6):722-737
Cell death and differentiation 2024 Jun;31(6):722-737
An ATPase-Mimicking MXene nanozyme pharmacologically breaks the ironclad defense system for ferroptosis cancer therapy.
Wang H, Liu X, Yan X, Du Y, Pu F, Ren J, Qu X
Biomaterials 2024 Jun;307:122523
Biomaterials 2024 Jun;307:122523
Transient receptor potential mucolipin 1 circumvents oxidative stress in primary human melanocytes.
Chen Y, Xie B, Hu Y, Sun J, Xu J, Shen Y, Zhu Y, Song X
Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI) 2024 Jun;30(6):e13772
Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI) 2024 Jun;30(6):e13772
LUC7L3 is a downstream factor of SRSF1 and prevents genomic instability.
Zhang X, Guo J, Shi X, Zhou X, Chen Q
Cell insight 2024 Jun;3(3):100170
Cell insight 2024 Jun;3(3):100170
Identification critical host factors for Japanese encephalitis virus replication via CRISPR screening of human sgRNA library.
Liu LL, Yin YQ, Ma KX, Xing JC, Ren XX, Huang JY, Liao M, Qi WB, Huang LH
Veterinary microbiology 2024 Jun;293:110099
Veterinary microbiology 2024 Jun;293:110099
Staphylococcus aureus promotes its intracellular survival by inhibiting Rab11-Rab11FIP4-mediated vesicle trafficking.
Xu H, Wang X, Zhang Z, Hu J, Yu Y, Wang J, Liu Y, Liu J
Veterinary microbiology 2024 Jun;293:110091
Veterinary microbiology 2024 Jun;293:110091
A novel mitochondrial unfolded protein response-related risk signature to predict prognosis, immunotherapy and sorafenib sensitivity in hepatocellular carcinoma.
Zhang S, Guo H, Wang H, Liu X, Wang M, Liu X, Fan Y, Tan K
Apoptosis : an international journal on programmed cell death 2024 Jun;29(5-6):768-784
Apoptosis : an international journal on programmed cell death 2024 Jun;29(5-6):768-784
Circ_0098823 binding with IGF2BP3 regulates DNM1L stability to promote metastasis of hepatocellular carcinoma via mitochondrial fission.
Yan J, Wang X, Fan Z, Xu Y, Zhang Y, Liu Y, Guo L, Liu D
Apoptosis : an international journal on programmed cell death 2024 Jun;29(5-6):709-725
Apoptosis : an international journal on programmed cell death 2024 Jun;29(5-6):709-725
The total xanthones extracted from Gentianella acuta alleviates HFpEF by activating the IRE1α/Xbp1s pathway.
Zhao L, Qin Y, Liu Y, An L, Liu W, Zhang C, Song Q, Dai C, Zhang J, Li A
Journal of cellular and molecular medicine 2024 Jun;28(11):e18466
Journal of cellular and molecular medicine 2024 Jun;28(11):e18466
Mechanistic of AMPK/ACC2 regulating myoblast differentiation by fatty acid oxidation of goat.
Kang Z, Zhang Z, Li J, Deng K, Wang F, Fan Y
International journal of biological macromolecules 2024 Jun;270(Pt 2):132243
International journal of biological macromolecules 2024 Jun;270(Pt 2):132243
YTHDF1 regulates immune cell infiltration in gastric cancer via interaction with p53.
Liao Q, Xiong J
Experimental and therapeutic medicine 2024 Jun;27(6):255
Experimental and therapeutic medicine 2024 Jun;27(6):255
Mammalian IRE1α dynamically and functionally coalesces with stress granules.
Liu S, Zhang X, Yao X, Wang G, Huang S, Chen P, Tang M, Cai J, Wu Z, Zhang Y, Xu R, Liu K, He K, Wang Y, Jiang L, Wang QA, Rui L, Liu J, Liu Y
Nature cell biology 2024 Jun;26(6):917-931
Nature cell biology 2024 Jun;26(6):917-931
Calmodulin 2 expression is associated with poor prognosis in breast cancer.
Yang J, Li S, Wang J, Liu G, Zhang C, Li X, Liu X
Pathology, research and practice 2024 Jun;258:155326
Pathology, research and practice 2024 Jun;258:155326
The SGLT2 inhibitor empagliflozin inhibits skeletal muscle fibrosis in naturally aging male mice through the AMPKα/MMP9/TGF-β1/Smad pathway.
Huang Q, Chen J, Liao S, Long J, Fang R, He Y, Chen P, Liu D
Biogerontology 2024 Jun;25(3):567-581
Biogerontology 2024 Jun;25(3):567-581
Exosomal lncRNA-MIAT promotes neovascularization via the miR-133a-3p/MMP-X1 axis in diabetic retinopathy.
Li X, Cao Q, Xu C, Wang J, Pan T, Liu Q, Xie P, Hu Z
Experimental eye research 2024 Jun;243:109912
Experimental eye research 2024 Jun;243:109912
Amyloid precursor protein induces reactive astrogliosis.
Velezmoro Jauregui G, Vukić D, Onyango IG, Arias C, Novotný JS, Texlová K, Wang S, Kovačovicova KL, Polakova N, Zelinkova J, Čarna M, Lacovich V, Head BP, Havas D, Mistrik M, Zorec R, Verkhratsky A, Keegan L, O'Connell MA, Rissman R, Stokin GB
Acta physiologica (Oxford, England) 2024 Jun;240(6):e14142
Acta physiologica (Oxford, England) 2024 Jun;240(6):e14142
LncRNA HOTAIR promotes the migration and invasion of cervical cancer through DNMT3B/LATS1/ YAP1 pS127 axis.
Zhang Z, Zhou X, Li J, Meng Q, Zheng P
Reproductive biology 2024 Jun;24(2):100893
Reproductive biology 2024 Jun;24(2):100893
ZNF263 cooperates with ZNF31 to promote the drug resistance and EMT of pancreatic cancer through transactivating RNF126.
Zhang J, Chen C, Geng Q, Li H, Wu M, Chan B, Wang S, Sheng W
Journal of cellular physiology 2024 Jun;239(6):e31259
Journal of cellular physiology 2024 Jun;239(6):e31259
Vasorin as an actor of bone turnover?
Andrique C, Bonnet AL, Dang J, Lesieur J, Krautzberger AM, Baroukh B, Torrens C, Sadoine J, Schmitt A, Rochefort GY, Bardet C, Six I, Houillier P, Tharaux PL, Schrewe H, Gaucher C, Chaussain C
Journal of cellular physiology 2024 Jun;239(6):e31257
Journal of cellular physiology 2024 Jun;239(6):e31257
Overexpression of KAT8 induces a failure in early embryonic development in mice.
Wu X, Wang S, Guo Y, Zeng S
Theriogenology 2024 Jun;221:31-37
Theriogenology 2024 Jun;221:31-37
Hydrogen alleviates impaired lung epithelial barrier in acute respiratory distress syndrome via inhibiting Drp1-mediated mitochondrial fission through the Trx1 pathway.
Long Y, Ang Y, Chen W, Wang Y, Shi M, Hu F, Zhou Q, Shi Y, Ge B, Peng Y, Yu W, Bao H, Li Q, Duan M, Gao J
Free radical biology & medicine 2024 Jun;218:132-148
Free radical biology & medicine 2024 Jun;218:132-148
Bispecific Nanobody-Aptamer Conjugates for Enhanced Cancer Therapy in Solid Tumors.
Wang Y, Chen J, Zhang S, Jiang H, Zhu J, Jiang G, Liu Y, Zhu Y, Li J
Small (Weinheim an der Bergstrasse, Germany) 2024 Jun;20(25):e2308265
Small (Weinheim an der Bergstrasse, Germany) 2024 Jun;20(25):e2308265
RBM3 enhances the stability of MEF2C mRNA and modulates blood-brain barrier permeability in AD microenvironment.
Ding Y, Lin M, Wang J, Shang X
Biochimica et biophysica acta. Molecular cell research 2024 Jun;1871(5):119738
Biochimica et biophysica acta. Molecular cell research 2024 Jun;1871(5):119738
CILP2 promotes hypertrophic scar through Snail acetylation by interaction with ACLY.
Wang J, Du J, Wang Y, Song Y, Wu J, Wang T, Yu Z, Song B
Biochimica et biophysica acta. Molecular basis of disease 2024 Jun;1870(5):167202
Biochimica et biophysica acta. Molecular basis of disease 2024 Jun;1870(5):167202
Urotensin II receptor deficiency ameliorates ligation-induced carotid intimal hyperplasia partially through the RhoA-YAP1 pathway.
Wei P, Tian K, Liu H, Li K, Alam N, Cheng D, Li M, He X, Guo J, Wang R, Wang W, Bai L, Liu E, Xu B, Li Y, Zhao S
Biochimica et biophysica acta. Molecular basis of disease 2024 Jun;1870(5):167170
Biochimica et biophysica acta. Molecular basis of disease 2024 Jun;1870(5):167170
Armed with IL-2 based fusion protein improves CAR-T cell fitness and efficacy against solid tumors.
Li S, Xia Y, Hou R, Wang X, Zhao X, Guan Z, Ma W, Xu Y, Zhang W, Liu D, Zheng J, Shi M
Biochimica et biophysica acta. Molecular basis of disease 2024 Jun;1870(5):167159
Biochimica et biophysica acta. Molecular basis of disease 2024 Jun;1870(5):167159
OTUD1 enhances gastric cancer aggressiveness by deubiquitinating EBV-encoded protein BALF1 to stabilize the apoptosis inhibitor Bcl-2.
Lin H, Han Y, Sang Y, Wu Y, Tian M, Chen X, Lin X, Lin X
Biochimica et biophysica acta. Molecular basis of disease 2024 Jun;1870(5):167132
Biochimica et biophysica acta. Molecular basis of disease 2024 Jun;1870(5):167132
The antidepressant effects of protein arginine methyltransferase 2 involve neuroinflammation.
Liu S, Zhang B, Guo H, Ding Z, Hou W, Hu X, Wang Y, Tan W, Zhou S
Neurochemistry international 2024 Jun;176:105728
Neurochemistry international 2024 Jun;176:105728
Alpha-tocopherol inhibits ferroptosis and promotes neural function recovery in rats with spinal cord injury via downregulating Alox15.
Zhu R, Kang Y, Li Q, Peng K, Shi X, Yin Z, Xuan Y
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Jun;175:116734
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Jun;175:116734
Therapeutic antibody engineering for efficient targeted degradation of membrane proteins in lysosomes.
Gauthier C, Daurat M, Ali LMA, El Cheikh K, El Bahlagui I, Taliercio C, Morère E, Gary-Bobo M, Morère A, Garcia M, Maynadier M, Basile I
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Jun;175:116707
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Jun;175:116707
Kokusaginine attenuates renal fibrosis by inhibiting the PI3K/AKT signaling pathway.
Wang Y, Han Y, Shang K, Xiao J, Tao L, Peng Z, Liu S, Jiang Y
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Jun;175:116695
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Jun;175:116695
Prednisone combined with Dihydroartemisinin attenuates systemic lupus erythematosus by regulating M1/M2 balance through the MAPK signaling pathway.
Chen Y, Tao T, Liang Z, Chen X, Xu Y, Zhang T, Zhou D
Molecular immunology 2024 Jun;170:144-155
Molecular immunology 2024 Jun;170:144-155
High glucose promotes atherosclerosis by regulating miRNA let7d-5p level.
Wang H, Liu F, Zhao W, Guo Y, Mai P, Zhao S, Wen Z, Su J, Li X, Wang Y, Zhang Y
Journal of diabetes investigation 2024 Jun;15(6):711-724
Journal of diabetes investigation 2024 Jun;15(6):711-724
SLC34A2 promotes cell proliferation by activating STX17-mediated autophagy in esophageal squamous cell carcinoma.
Xu Y, Duan S, Ye W, Zheng Z, Zhang J, Gao Y, Ye S
Thoracic cancer 2024 Jun;15(17):1369-1384
Thoracic cancer 2024 Jun;15(17):1369-1384
Rapid identifying of COX-2 inhibitors from turmeric (Curcuma longa) by bioaffinity ultrafiltration coupled with UPLC-Q Exactive-Orbitrap-MS and zebrafish-based in vivo validation.
Lan Z, Yang R, Wang H, Xue X, Sun Y, Wang S, Zhang Y, Meng J
Bioorganic chemistry 2024 Jun;147:107357
Bioorganic chemistry 2024 Jun;147:107357
Dual inhibition of oxidative phosphorylation and glycolysis to enhance cancer therapy.
Sheng X, Wang MM, Zhang GD, Su Y, Fang HB, Yu ZH, Su Z
Bioorganic chemistry 2024 Jun;147:107325
Bioorganic chemistry 2024 Jun;147:107325
Gastrodin regulates the TLR4/TRAF6/NF-κB pathway to reduce neuroinflammation and microglial activation in an AD model.
Wang W, Wang Y, Wang F, Xie G, Liu S, Li Z, Wang P, Liu J, Lin L
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jun;128:155518
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jun;128:155518
Combining cisplatin with Pinellia pedatisecta Schott lipid-soluble extract induces tumor immunogenic cell death in cervical cancer.
Wang C, Zhang M, Peng J, Zhang M, Lu C, Qi X, Luo Q, Wang Y, Li G
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jun;128:155504
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jun;128:155504
Silibinin is a suppressor of the metastasis-promoting transcription factor ID3.
Verdura S, Encinar JA, Gratchev A, Llop-Hernández À, López J, Serrano-Hervás E, Teixidor E, López-Bonet E, Martin-Castillo B, Micol V, Bosch-Barrera J, Cuyàs E, Menendez JA
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jun;128:155493
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jun;128:155493
Astragalus polysaccharides attenuate chemotherapy-induced immune injury by modulating gut microbiota and polyunsaturated fatty acid metabolism.
Wang H, Zhu W, Hong Y, Wei W, Zheng N, He X, Bao Y, Gao X, Huang W, Sheng L, Li M, Li H
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jun;128:155492
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jun;128:155492
Baicalein improves the symptoms of polycystic ovary syndrome by mitigating oxidative stress and ferroptosis in the ovary and gravid placenta.
Li YY, Peng YQ, Yang YX, Shi TJ, Liu RX, Luan YY, Yin CH
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jun;128:155423
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jun;128:155423
Exploring Ca(2+) Dynamics in Myelinating Oligodendrocytes through rAAV-Mediated jGCaMP8s Expression in Developing Spinal Cord Organ Cultures.
Pachetti M, Palandri A, de Castro Reis F, Recupero L, Ballerini L
eNeuro 2024 Jun;11(6)
eNeuro 2024 Jun;11(6)
N(6)-Methyladenosine-Modified KREMEN2 Promotes Tumorigenesis and Malignant Progression of High-Grade Serous Ovarian Cancer.
Hou R, Wang Y, Cao S, Sun X, Jiang L
Laboratory investigation; a journal of technical methods and pathology 2024 Jun;104(6):102059
Laboratory investigation; a journal of technical methods and pathology 2024 Jun;104(6):102059
Computer-aided discovery of novel aryl hydrocarbon receptor ligands to regulate CYP1A1 expression in inflammatory macrophages.
Chen K, Luo L, Tu G, Yang J, Pu W, Zhu J, Xue W, Zhang R
Chemical biology & drug design 2024 Jun;103(6):e14572
Chemical biology & drug design 2024 Jun;103(6):e14572
Effects of lighted incubation and foraging enrichment during rearing on individual fear behavior, corticosterone, and neuroplasticity in laying hen pullets.
Kliphuis S, Manet MWE, Goerlich VC, Nordquist RE, Vernooij H, Tuyttens FAM, Rodenburg TB
Poultry science 2024 Jun;103(6):103665
Poultry science 2024 Jun;103(6):103665
Pan-Cancer Proteomics Analysis Reveals Wiskott-Aldrich Syndrome Protein as a Potential Regulator of Programmed Death-Ligand 1.
Hu L, Liu D, Zheng D, Lu J, Yuan X, Li Y, Shi F, Shi X, He QY, Li Q, Zhang CZ
Journal of proteome research 2024 Jun 7;23(6):2195-2205
Journal of proteome research 2024 Jun 7;23(6):2195-2205
Mechanistic insights into super-enhancer-related genes as prognostic signatures in colon cancer.
Tang Y, Sang S, Gao S, Xu W, Zhou H, Xia X
Aging 2024 Jun 7;16(11):9918-9932
Aging 2024 Jun 7;16(11):9918-9932
linc01152 Regulates Cell Viability, Cell Migration and Cell Invasion of Breast Cancer via Regulating miR-320a and MTDH.
Zhu Z, Lin S, Pang L
Biochemical genetics 2024 Jun 7;
Biochemical genetics 2024 Jun 7;
Depletion of cap-binding protein eIF4E dysregulates amino acid metabolic gene expression.
Diamond PD, McGlincy NJ, Ingolia NT
Molecular cell 2024 Jun 6;84(11):2119-2134.e5
Molecular cell 2024 Jun 6;84(11):2119-2134.e5
Involvement of necroptotic cell death in macrophages in progression of bleomycin and LPS-induced acute exacerbation of idiopathic pulmonary fibrosis.
Koike A, Hayashi K, Fujimori K
European journal of pharmacology 2024 Jun 5;972:176572
European journal of pharmacology 2024 Jun 5;972:176572
N6022 attenuates cerebral ischemia/reperfusion injury-induced microglia ferroptosis by promoting Nrf2 nuclear translocation and inhibiting the GSNOR/GSTP1 axis.
Duan WL, Ma YP, Wang XJ, Ma CS, Han B, Sheng ZM, Dong H, Zhang LY, Li PA, Zhang BG, He MT
European journal of pharmacology 2024 Jun 5;972:176553
European journal of pharmacology 2024 Jun 5;972:176553
Resveratrol attenuates cyclosporin A-induced upregulation of the thromboxane A(2) receptor and hypertension via the AMPK/SIRT1 and MAPK/NF-κB pathways in the rat mesenteric artery.
Li Q, Cao H, Xu X, Chen Y, Zhang Y, Mi Y, Zhu X, Shi Y, Liu J, Wang B, Xu CB, Wang C
European journal of pharmacology 2024 Jun 5;972:176543
European journal of pharmacology 2024 Jun 5;972:176543
Identification of hub genes and potential therapeutic mechanisms related to HPV positive head and neck squamous carcinoma based on full transcriptomic detection and ceRNA network construction.
Wang K, Zhang T, Li X, Zhang X, Li R, Pan B, Deng J
Gene 2024 Jun 5;910:148321
Gene 2024 Jun 5;910:148321
A Recql5 mutant facilitates complex CRISPR/Cas9-mediated chromosomal engineering in mouse zygotes.
Iwata S, Nagahara M, Ido R, Iwamoto T
Genetics 2024 Jun 5;227(2)
Genetics 2024 Jun 5;227(2)
Microglial lipid droplet accumulation in tauopathy brain is regulated by neuronal AMPK.
Li Y, Munoz-Mayorga D, Nie Y, Kang N, Tao Y, Lagerwall J, Pernaci C, Curtin G, Coufal NG, Mertens J, Shi L, Chen X
Cell metabolism 2024 Jun 4;36(6):1351-1370.e8
Cell metabolism 2024 Jun 4;36(6):1351-1370.e8
lncRNA JPX Promotes Tumor Progression by Interacting with and Destabilizing YTHDF2 in Cutaneous Melanoma.
Luo D, Tang H, Tan L, Zhang L, Wang L, Cheng Q, Lei X, Wu J
Molecular cancer research : MCR 2024 Jun 4;22(6):524-537
Molecular cancer research : MCR 2024 Jun 4;22(6):524-537
2'-Hydroxycinnamaldehyde Alleviates Intestinal Inflammation by Attenuating Intestinal Mucosal Barrier Damage Via Directly Inhibiting STAT3.
Chen M, Wei S, Wu X, Xiang Z, Li X, He H, Liao F, Wang X, Zhang J, Yu B, Dong W
Inflammatory bowel diseases 2024 Jun 3;30(6):992-1008
Inflammatory bowel diseases 2024 Jun 3;30(6):992-1008
Neuroinflammation and Lysosomal Abnormalities Characterise the Essential Role for Oxidation Resistance 1 in the Developing and Adult Cerebellum.
Bucknor EMV, Johnson E, Efthymiou S, Alvi JR, Sultan T, Houlden H, Maroofian R, Karimiani EG, Finelli MJ, Oliver PL
Antioxidants (Basel, Switzerland) 2024 Jun 3;13(6)
Antioxidants (Basel, Switzerland) 2024 Jun 3;13(6)
FTO elicits tumor neovascularization in cancer-associated fibroblasts through eliminating m(6)A modifications of multiple pro-angiogenic factors.
Liao Q, Shi H, Yang J, Ge S, Jia R, Song X, Chai P, Jia R
Cancer letters 2024 Jun 28;592:216911
Cancer letters 2024 Jun 28;592:216911
NFIC mediates m6A mRNA methylation to orchestrate transcriptional and post-transcriptional regulation to represses malignant phenotype of non-small cell lung cancer cells.
Shi K, Chen Y, Liu R, Fu X, Guo H, Gao T, Wang S, Dou L, Wang J, Wu Y, Yu J, Yu H
Cancer cell international 2024 Jun 28;24(1):223
Cancer cell international 2024 Jun 28;24(1):223
Circular RNA HSDL2 promotes breast cancer progression via miR-7978 ZNF704 axis and regulating hippo signaling pathway.
Wang D, Yang S, Lyu M, Xu L, Zhong S, Yu D
Breast cancer research : BCR 2024 Jun 27;26(1):105
Breast cancer research : BCR 2024 Jun 27;26(1):105
TRIM26 deficiency enhancing liver regeneration through macrophage polarization and β-catenin pathway activation.
Li T, Zhong W, Li M, Shao Z, Zhang G, Wang W, Gao Z, Tan X, Xu Z, Luo F, Song G
Cell death & disease 2024 Jun 26;15(6):453
Cell death & disease 2024 Jun 26;15(6):453
Mammalian orthoreovirus capsid protein σ3 antagonizes RLR-mediated antiviral responses by degrading MAVS.
Li D, Mo R, Li X, Cheng R, Xie J, Li H, Yang Y, Li S, Li H, Yan Z, Wei S, Idris A, Li X, Feng R
mSphere 2024 Jun 25;9(6):e0023624
mSphere 2024 Jun 25;9(6):e0023624
Blockage of L2HGDH-mediated S-2HG catabolism orchestrates macrophage polarization to elicit antitumor immunity.
Feng S, Wang D, Jin Y, Huang S, Liang T, Sun W, Du X, Zhuo L, Shan C, Zhang W, Jing T, Zhao S, Hong R, You L, Liu G, Chen L, Ye D, Li X, Yang Y
Cell reports 2024 Jun 25;43(6):114300
Cell reports 2024 Jun 25;43(6):114300
Circular RNA circLIFR suppresses papillary thyroid cancer progression by modulating the miR-429/TIMP2 axis.
Zhang F, Li J, Xu J, Jiang X, Chen S, Nasser QA
Journal of cancer research and clinical oncology 2024 Jun 25;150(6):323
Journal of cancer research and clinical oncology 2024 Jun 25;150(6):323
Small Molecule-Inducible and Photoactivatable Cellular RNA N1-Methyladenosine Editing.
Xie G, Lu Y, He J, Yang X, Zhou J, Yi C, Li J, Li Z, Asadikaram G, Niu H, Xiong X, Li J, Wang H
Angewandte Chemie (International ed. in English) 2024 Jun 21;63(26):e202320029
Angewandte Chemie (International ed. in English) 2024 Jun 21;63(26):e202320029
Acetyl-NPKY of integrin-β1 binds KINDLIN2 to control endothelial cell proliferation and junctional integrity.
Sidibé A, Mykuliak VV, Zhang P, Hytönen VP, Wu J, Wehrle-Haller B
iScience 2024 Jun 21;27(6):110129
iScience 2024 Jun 21;27(6):110129
NIR-responsive CN-Pt-GEM hydrogel induces necroptosis and immunotherapeutic responses prevent postoperative recurrence and wound infection in lung carcinoma.
Wang M, Cai R, Zhang Z, Feng L, Lei Z, Wang F, Yu Z, Liu L, Yang X, Guo H, Shan B, Xu S, Guo R, Cui S, Zheng Y
Journal of nanobiotechnology 2024 Jun 21;22(1):355
Journal of nanobiotechnology 2024 Jun 21;22(1):355
Ophiobolin A Covalently Targets Mitochondrial Complex IV Leading to Metabolic Collapse in Cancer Cells.
Gowans FA, Thach DQ, Zhu Z, Wang Y, Altamirano Poblano BE, Dovala D, Tallarico JA, McKenna JM, Schirle M, Maimone TJ, Nomura DK
ACS chemical biology 2024 Jun 21;19(6):1260-1270
ACS chemical biology 2024 Jun 21;19(6):1260-1270
The Role of TPM3 in Protecting Cardiomyocyte from Hypoxia-Induced Injury via Cytoskeleton Stabilization.
Huang K, Yang W, Shi M, Wang S, Li Y, Xu Z
International journal of molecular sciences 2024 Jun 20;25(12)
International journal of molecular sciences 2024 Jun 20;25(12)
Circ_0004851 regulates the molecular mechanism of miR-296-3p/FGF11 in the influence of high iodine on PTC.
Li JJ, Ru ZX, Yang X, Sun JX, Wu YM, Yang XY, Hou BY, Xue B, Ding C, Qiao H
Journal of translational medicine 2024 Jun 20;22(1):586
Journal of translational medicine 2024 Jun 20;22(1):586
Neutrophil extracellular traps induce pyroptosis of pulmonary microvascular endothelial cells by activating the NLRP3 inflammasome.
Zhao P, Zhu J, Bai L, Ma W, Li F, Zhang C, Zhao L, Wang L, Zhang S
Clinical and experimental immunology 2024 Jun 20;217(1):89-98
Clinical and experimental immunology 2024 Jun 20;217(1):89-98
RANKL/RANK signaling recruits Tregs via the CCL20-CCR6 pathway and promotes stemness and metastasis in colorectal cancer.
Ouyang J, Hu S, Zhu Q, Li C, Kang T, Xie W, Wang Y, Li Y, Lu Y, Qi J, Xia M, Chen J, Yang Y, Sun Y, Gao T, Ye L, Liang Q, Pan Y, Zhu C
Cell death & disease 2024 Jun 20;15(6):437
Cell death & disease 2024 Jun 20;15(6):437
Network pharmacology and biochemical experiments reveal the antiapoptotic mechanism of huperzine A for treating diabetic retinopathy.
Zhang Y, Huang W, Tian Q, Bai G, Wu W, Yin H, Hu L, Chen X
The British journal of ophthalmology 2024 Jun 20;108(7):989-998
The British journal of ophthalmology 2024 Jun 20;108(7):989-998
CSTF3 contributes to platinum resistance in ovarian cancer through alternative polyadenylation of lncRNA NEAT1 and generating the short isoform NEAT1_1.
Luo X, Wei Q, Jiang X, Chen N, Zuo X, Zhao H, Liu Y, Liu X, Xie L, Yang Y, Liu T, Yi P, Xu J
Cell death & disease 2024 Jun 19;15(6):432
Cell death & disease 2024 Jun 19;15(6):432
Glutamatergic neuronal activity regulates angiogenesis and blood-retinal barrier maturation via Norrin/β-catenin signaling.
Biswas S, Shahriar S, Bachay G, Arvanitis P, Jamoul D, Brunken WJ, Agalliu D
Neuron 2024 Jun 19;112(12):1978-1996.e6
Neuron 2024 Jun 19;112(12):1978-1996.e6
Loss of FAM172A gene prompts cell proliferation in liver regeneration.
Wei H, Zhang Y, Gao M, Yang J, Wang S, Zhou X, Wei H, Xiao F
Molecular and cellular biochemistry 2024 Jun 19;
Molecular and cellular biochemistry 2024 Jun 19;
Stachydrine hydrochloride protects the ischemic heart by ameliorating endoplasmic reticulum stress through a SERCA2a dependent way and maintaining intracellular Ca(2+) homeostasis.
Feng M, Chen Y, Chen J, Guo W, Zhao P, Zhang C, Shan X, Chen H, Xu M, Lu R
European journal of pharmacology 2024 Jun 15;973:176585
European journal of pharmacology 2024 Jun 15;973:176585
Study on the mechanism of S100A4-mediated cancer oncogenesis in uveal melanoma cells through the integration of bioinformatics and in vitro experiments.
Chen H, Zhang W, Shi J, Tang Y, Chen X, Li J, Yao X
Gene 2024 Jun 15;911:148333
Gene 2024 Jun 15;911:148333
Sodium arsenite induces hepatic stellate cells activation by m(6)A modification of TGF-β1 during liver fibrosis.
Qiu T, Hou K, Zhang J, Wang N, Yao X, Yang G, Jiang L, Dong J, Miao M, Bai J, Sun X
Ecotoxicology and environmental safety 2024 Jun 15;278:116435
Ecotoxicology and environmental safety 2024 Jun 15;278:116435
Tat-NR2B9c attenuates oxidative stress via inhibition of PSD95-NR2B-nNOS complex after subarachnoid hemorrhage in rats.
Zhang H, Xu L, He Y, Zhang Z, Zhang J, Yu Q, Liu Y, Wang X, Zhang A, Wang K, Fang Y, Chen S
Neuropharmacology 2024 Jun 15;251:109905
Neuropharmacology 2024 Jun 15;251:109905
CK1δ/ε kinases regulate TDP-43 phosphorylation and are therapeutic targets for ALS-related TDP-43 hyperphosphorylation.
Ko VI, Ong K, Cleveland DW, Yu H, Ravits JM
Neurobiology of disease 2024 Jun 15;196:106516
Neurobiology of disease 2024 Jun 15;196:106516
Trim27 aggravates airway inflammation and oxidative stress in asthmatic mice via potentiating the NLRP3 inflammasome.
Liu K, Gu Y, Gu S, Song L, Hua S, Li D, Tang M
International immunopharmacology 2024 Jun 15;134:112199
International immunopharmacology 2024 Jun 15;134:112199
A novel Senescence-Based prognostic model unveils tumor interactions and drug resistance in colorectal cancer.
Yue Y, She X, Ding W, Chen S, Xiao Q, Pan B, Zhou L, Yin Y, Li Y, Wang S, Xu M
International immunopharmacology 2024 Jun 15;134:112197
International immunopharmacology 2024 Jun 15;134:112197
Recombinant fibroblast growth factor 4 ameliorates axonal regeneration and functional recovery in acute spinal cord injury through altering microglia/macrophage phenotype.
Li R, Feng J, Li L, Luo G, Shi Y, Shen S, Yuan X, Wu J, Yan B, Yang L
International immunopharmacology 2024 Jun 15;134:112188
International immunopharmacology 2024 Jun 15;134:112188
Cardiac Fibroblasts Enhance MMP2 Activity to Suppress Gap Junction Function in Cardiomyocytes.
Bai X, Huang X, Yi J, Yan X, Hu T, Wang L, Wang Z, Gao H
Applied biochemistry and biotechnology 2024 Jun 15;
Applied biochemistry and biotechnology 2024 Jun 15;
Absent in Melanoma 2 Mediates Inflammasome Signaling Activation against Clostridium perfringens Infection.
Ma Z, Lou Y, Wang N, Zhao Y, Zhang S, Zhang M, Li J, Xu Q, He A, Yu S
International journal of molecular sciences 2024 Jun 14;25(12)
International journal of molecular sciences 2024 Jun 14;25(12)
Prostate Cancer-Specific Lysine 53 Acetylation of Cytochrome c Drives Metabolic Reprogramming and Protects from Apoptosis in Intact Cells.
Morse PT, Wan J, Arroum T, Herroon MK, Kalpage HA, Bazylianska V, Lee I, Heath EI, Podgorski I, Hüttemann M
Biomolecules 2024 Jun 14;14(6)
Biomolecules 2024 Jun 14;14(6)
Inhibition and reversal of a TGF-β1 induced myofibroblast phenotype by adipose tissue-derived paracrine factors.
Higginbotham S, Workman VL, Giblin AV, Green NH, Lambert DW, Hearnden V
Stem cell research & therapy 2024 Jun 13;15(1):166
Stem cell research & therapy 2024 Jun 13;15(1):166
Therapeutic potential of CB(1)R activation by Qingyangshen glycoside M1 for seizure relief.
Mu X, Ma ZB, Chen H, Liang R, Li Z, Guo XX, Xu TR, Xiang C
Journal of ethnopharmacology 2024 Jun 12;327:117982
Journal of ethnopharmacology 2024 Jun 12;327:117982
Xanthoceras sorbifolium leaves alleviate hyperuricemic nephropathy by inhibiting the PI3K/AKT signaling pathway to regulate uric acid transport.
Liu Y, Han Y, Liu Y, Huang C, Feng W, Cui H, Li M
Journal of ethnopharmacology 2024 Jun 12;327:117946
Journal of ethnopharmacology 2024 Jun 12;327:117946
Human gastric cancer progression and stabilization of ATG2B through RNF5 binding facilitated by autophagy-associated CircDHX8.
Wei G, Chen X, Ruan T, Ma X, Zhu X, Wen W, He D, Tao K, Wu C
Cell death & disease 2024 Jun 12;15(6):410
Cell death & disease 2024 Jun 12;15(6):410
Terpinen-4-ol Improves Lipopolysaccharide-Induced Macrophage Inflammation by Regulating Glutamine Metabolism.
Liu Y, Tang X, Zhang H, Zheng L, Lai P, Guo C, Ma J, Chen H, Qiu L
Foods (Basel, Switzerland) 2024 Jun 12;13(12)
Foods (Basel, Switzerland) 2024 Jun 12;13(12)
Attenuating bone loss in osteoporosis: the potential of corylin (CL) as a therapeutic agent.
Zhou S, Huang J, Chen K, Wang Q, Liu Z, Sun Y, Yin F, Wang S, Pang Z, Ma M
Aging 2024 Jun 11;16(11):9569-9583
Aging 2024 Jun 11;16(11):9569-9583
d-mannose targets PD-1 to lysosomal degradation and enhances T cell-mediated anti-tumor immunity.
Dong W, Lin M, Zhang R, Sun X, Li H, Liu T, Xu Y, Lv L
Cancer letters 2024 Jun 1;591:216883
Cancer letters 2024 Jun 1;591:216883
FBXO43 promotes cell cycle progression in cancer cells through stabilizing SKP2.
Zheng L, Shen J, Chen Y, Lin J, Li P, Zhao X, Ren H, Sun Y, Wang Z
Cancer letters 2024 Jun 1;591:216848
Cancer letters 2024 Jun 1;591:216848
Forsythiaside A attenuates lipopolysaccharide-induced mouse mastitis by activating autophagy and regulating gut microbiota and metabolism.
Gao Y, Hao Z, Zhang H, Liu J, Zhou G, Wen H, Su Q, Tong C, Huang S, Wang X
Chemico-biological interactions 2024 Jun 1;396:111044
Chemico-biological interactions 2024 Jun 1;396:111044
Tobacco toxins trigger bone marrow mesenchymal stem cells aging by inhibiting mitophagy.
Xiang K, Ren M, Liu F, Li Y, He P, Gong X, Chen T, Wu T, Huang Z, She H, Liu K, Jing Z, Yang S
Ecotoxicology and environmental safety 2024 Jun 1;277:116392
Ecotoxicology and environmental safety 2024 Jun 1;277:116392
Overexpression of FHL1 suppresses papillary thyroid cancer proliferation and progression via inhibiting Wnt/β-catenin pathway.
Chen J, Zeng C, Jin J, Zhang P, Zhang Y, Zhang H, Li Y, Guan H
Endocrine 2024 Jul;85(1):238-249
Endocrine 2024 Jul;85(1):238-249
CK2 activity is crucial for proper glucagon expression.
Ampofo E, Pack M, Wrublewsky S, Boewe AS, Spigelman AF, Koch H, MacDonald PE, Laschke MW, Montenarh M, Götz C
Diabetologia 2024 Jul;67(7):1368-1385
Diabetologia 2024 Jul;67(7):1368-1385
HHLA2 promotes hepatoma cell proliferation, migration, and invasion via SPP1/PI3K/AKT signaling pathway.
Wang J, Yang K, Yang X, Jin T, Tian Y, Dai C, Xu F
Molecular carcinogenesis 2024 Jul;63(7):1275-1287
Molecular carcinogenesis 2024 Jul;63(7):1275-1287
Hypomethylation-associated LINC00987 downregulation induced lung adenocarcinoma progression by inhibiting the phosphorylation-mediated degradation of SND1.
Lai Q, Wan Y, Zhang Y, Huang Y, Tang Q, Chen M, Li Q, Ma K, Xiao P, Luo C, Zhuang X
Molecular carcinogenesis 2024 Jul;63(7):1260-1274
Molecular carcinogenesis 2024 Jul;63(7):1260-1274
Loss of PTPRS elicits potent metastatic capability and resistance to temozolomide in glioblastoma.
Zhang Y, Chang L, Huang P, Cao M, Hong R, Zhao X, He X, Xu L
Molecular carcinogenesis 2024 Jul;63(7):1235-1247
Molecular carcinogenesis 2024 Jul;63(7):1235-1247
Selenium nanoparticles decorated with polysaccharides from Sargassum fusiforme protects against 6-OHDA-induced neurotoxicity in PC12 cells and rat model of Parkinson's disease.
Zhao H, Song J, Wang T, Fan X
Nanomedicine : nanotechnology, biology, and medicine 2024 Jul;59:102755
Nanomedicine : nanotechnology, biology, and medicine 2024 Jul;59:102755
MSRB2 Ameliorates H(2)O(2)-induced Chondrocyte Oxidative Stress and Suppresses Apoptosis in Osteoarthritis.
Huang K, Fu W, Wang A, Du G, Tang H, Yin L, Yin Z, Gao W
Immunological investigations 2024 Jul;53(5):813-829
Immunological investigations 2024 Jul;53(5):813-829
Parkin deficiency promotes liver cancer metastasis by TMEFF1 transcription activation via TGF-β/Smad2/3 pathway.
Su Q, Wang JJ, Ren JY, Wu Q, Chen K, Tu KH, Zhang Y, Leong SW, Sarwar A, Han X, Zhang M, Dai WF, Zhang YM
Acta pharmacologica Sinica 2024 Jul;45(7):1520-1529
Acta pharmacologica Sinica 2024 Jul;45(7):1520-1529
Vagus nerve stimulation as a promising neuroprotection for ischemic stroke via α7nAchR-dependent inactivation of microglial NLRP3 inflammasome.
Xia XM, Duan Y, Wang YP, Han RX, Dong YF, Jiang SY, Zheng Y, Qiao C, Cao L, Lu X, Lu M
Acta pharmacologica Sinica 2024 Jul;45(7):1349-1365
Acta pharmacologica Sinica 2024 Jul;45(7):1349-1365
HMGB2 is a biomarker associated with poor prognosis promoting radioresistance in glioma by targeting base excision repair pathway.
Han W, Zhou H, Zhang X, Li H, Han X, Su L, Tian L, Xue X
Translational oncology 2024 Jul;45:101977
Translational oncology 2024 Jul;45:101977
Physiologically based pharmacokinetic modeling for confirming the role of CYP3A1/2 and P-glycoprotein in detoxification mechanism between glycyrrhizic acid and aconitine in rats.
Jin J, Xu X, Li F, Weng F, Zou B, Li Y, Zhao J, Zhang S, Yan D, Qiu F
Journal of applied toxicology : JAT 2024 Jul;44(7):978-989
Journal of applied toxicology : JAT 2024 Jul;44(7):978-989
PM(2.5) exposure inhibits osteoblast differentiation by increasing the ubiquitination and degradation of Smad4.
Yang J, Han C, Ye J, Hu X, Wang R, Shen J, Li L, Hu G, Shi X, Jia Z, Qu X, Liu H, Zhang X, Wu Y
Toxicology letters 2024 Jul;398:127-139
Toxicology letters 2024 Jul;398:127-139
Asiatic acid inhibits osteosarcoma cell migration and invasion via the AKT/Sp1/MMP1 axis.
Law YY, Lee HL, Lin CL, Chen PN, Wang PH, Hsieh YH, Chen CM
Environmental toxicology 2024 Jul;39(7):3920-3929
Environmental toxicology 2024 Jul;39(7):3920-3929
STAU1 exhibits a dual function by promoting amyloidogenesis and tau phosphorylation in cultured cells.
Li CL, Zhou GF, Xie XY, Wang L, Chen X, Pan QL, Pu YL, Yang J, Song L, Chen GJ
Experimental neurology 2024 Jul;377:114805
Experimental neurology 2024 Jul;377:114805
Influence of METTL3 knockdown on PDLSC osteogenesis in E. coli LPS-induced inflammation.
Chen H, Peng L, Wang Z, He Y, Zhang X
Oral diseases 2024 Jul;30(5):3225-3238
Oral diseases 2024 Jul;30(5):3225-3238
Estrogen inhibits TGF‑β1‑stimulated cardiac fibroblast differentiation and collagen synthesis by promoting Cdc42.
Xu J, Wang F, Li Y, Li P, Zhang Y, Xu G, Sun K, Huang Y
Molecular medicine reports 2024 Jul;30(1)
Molecular medicine reports 2024 Jul;30(1)
GPX7 reduces chondrocyte inflammation and extracellular matrix degradation triggered by IL‑1β, via a mechanism mediated by ferroptosis.
Chen B, Fu W, Jie C, Zhang G, Li Z, Liu Y, Zhou S
Molecular medicine reports 2024 Jul;30(1)
Molecular medicine reports 2024 Jul;30(1)
Mefunidone ameliorates acute liver failure in mice by inhibiting MKK4-JNK pathway.
Zhang Y, He X, Gu L, Li S, Tang J, Ma R, Yang H, Peng Z
Biochemical pharmacology 2024 Jul;225:116267
Biochemical pharmacology 2024 Jul;225:116267
Chronic Fluoride Exposure Induces Ovarian Dysfunction and Potential Association with Premature Ovarian Failure in Female Rats.
Tang X, Li H, Wang Y, Zeng L, Long L, Qu Y, Yang H, Zhang X, Li Y, Yu Y, Zhou Q, Luo M
Biological trace element research 2024 Jul;202(7):3225-3236
Biological trace element research 2024 Jul;202(7):3225-3236
Knockdown of LncRNA Lcn2-204 alleviates sepsis-induced myocardial injury by regulation of iron overload and ferroptosis.
Huang Y, Li L, Li Y, Lu N, Qin H, Wang R, Li W, Cheng Z, Li Z, Kang P, Ye H, Gao Q
Journal of molecular and cellular cardiology 2024 Jul;192:79-93
Journal of molecular and cellular cardiology 2024 Jul;192:79-93
Multiomics Analysis Reveals Leucine Deprivation Promotes Bile Acid Synthesis by Upregulating Hepatic CYP7A1 and Intestinal Turicibacter sanguinis in Mice.
Niu YR, Yu HN, Yan ZH, Yan XH
The Journal of nutrition 2024 Jul;154(7):1970-1984
The Journal of nutrition 2024 Jul;154(7):1970-1984
A novel selenium nanocomposite modified by AANL inhibits tumor growth by upregulating CLK2 in lung cancer.
Zhang Y, Chen Y, Wang B, Cai Y, Zhang M, Guo X, Wu A, Wang W, Liu N, Wang X, Gong Y, Pan J, Jin Y
Bioorganic chemistry 2024 Jul;148:107459
Bioorganic chemistry 2024 Jul;148:107459
Protective effects of Wenqingyin on sepsis-induced acute lung injury through regulation of the receptor for advanced glycation end products pathway.
Xie L, Zhang G, Wu Y, Hua Y, Ding W, Han X, Liu B, Zhou C, Li A
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jul;129:155654
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jul;129:155654
Antidiabetic action of the Chinese formula Shouhuitongbian and the underlying mechanism associated with alteration of gut microbiota.
Wang T, Liao H, Lin J, Zhang M, Chen B, Yin R, Sun J, Dai H, Liu H
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jul;129:155575
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jul;129:155575
Effects of xylo-oligosaccharide on gut microbiota, brain protein expression, and lipid profile induced by high-fat diet.
Teng CY, Kao NJ, Nguyen NTK, Lin CI, Cross TL, Lin SH
The Journal of nutritional biochemistry 2024 Jul;129:109640
The Journal of nutritional biochemistry 2024 Jul;129:109640
Effects of spinal cord injury associated exosomes delivered tRF-41 on the progression of spinal cord injury progression.
Cai H, Zhang Y, Meng F, Li Y
Genomics 2024 Jul;116(4):110885
Genomics 2024 Jul;116(4):110885
CYP3A5 unexpectedly regulates glucose metabolism through the AKT-TXNIP-GLUT1 axis in pancreatic cancer.
Shao M, Pan Q, Tan H, Wu J, Lee HW, Huber AD, Wright WC, Cho JH, Yu J, Peng J, Chen T
Genes & diseases 2024 Jul;11(4):101079
Genes & diseases 2024 Jul;11(4):101079
Estrogen promotes gonadotropin-releasing hormone expression by regulating tachykinin 3 and prodynorphin systems in chicken.
Wu X, Zhang Z, Li Y, Zhao Y, Ren Y, Tian Y, Hou M, Guo Y, Li Q, Tian W, Jiang R, Zhang Y, Gong Y, Li H, Li G, Liu X, Kang X, Li D, Tian Y
Poultry science 2024 Jul;103(7):103820
Poultry science 2024 Jul;103(7):103820
Long non-coding RNA KB-1460A1.5 promotes ferroptosis by inhibiting mTOR/SREBP-1/SCD1-mediated polyunsaturated fatty acid desaturation in glioma.
Xu L, Wen B, Wu Q, Lu S, Liao J, Mo L, Li Q, Tong X, Yan H
Carcinogenesis 2024 Jul 8;45(7):487-499
Carcinogenesis 2024 Jul 8;45(7):487-499
A novel framework for functional annotation of variants of uncertain significance in ID/ASD risk gene CC2D1A.
Bhattacharya A, Parlanti P, Cavallo L, Farrow E, Spivey T, Renieri A, Mari F, Manzini MC
Human molecular genetics 2024 Jul 6;33(14):1229-1240
Human molecular genetics 2024 Jul 6;33(14):1229-1240
Oridonin promotes RSL3-induced ferroptosis in breast cancer cells by regulating the oxidative stress signaling pathway JNK/Nrf2/HO-1.
Ye S, Hu X, Sun S, Su B, Cai J, Jiang J
European journal of pharmacology 2024 Jul 5;974:176620
European journal of pharmacology 2024 Jul 5;974:176620
MiR-29a efficiently suppresses the generation of reactive oxygen species and α-synuclein in a cellular model of Parkinson's disease by potentially targeting GSK-3β.
Yang YL, Lin TK, Huang YH
European journal of pharmacology 2024 Jul 5;974:176615
European journal of pharmacology 2024 Jul 5;974:176615
SUMOylation modification of FTO facilitates oxidative damage response of arsenic by IGF2BP3 in an m6A-dependent manner.
Zhang H, Chen Q, Han H, Guo C, Jiang X, Xia Y, Zhang Y, Zhou L, Zhang J, Tian X, Mao L, Qiu J, Zou Z, Chen C
Journal of hazardous materials 2024 Jul 5;472:134440
Journal of hazardous materials 2024 Jul 5;472:134440
Podophyllotoxin via SIRT1/PPAR /NF-κB axis induced cardiac injury in rats based on the toxicological evidence chain (TEC) concept.
Jiang T, Sun L, Wang Y, Zhang F, Guo J, Sun L, Jiang Y, Xue J, Duan J, Liu C
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jul 25;130:155655
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jul 25;130:155655
Single-Cell and Spatial Transcriptome Profiling Identifies the Transcription Factor BHLHE40 as a Driver of EMT in Metastatic Colorectal Cancer.
Yang S, Zhang D, Sun Q, Nie H, Zhang Y, Wang X, Huang Y, Sun Y
Cancer research 2024 Jul 2;84(13):2202-2217
Cancer research 2024 Jul 2;84(13):2202-2217
Vasorin Exocytosed from Glioma Cells Facilitates Angiogenesis via VEGFR2/AKT Signaling Pathway.
Zhong Y, Kang H, Ma Z, Li J, Qin Z, Zhang Z, Li P, Zhong Y, Wang L
Molecular cancer research : MCR 2024 Jul 2;22(7):668-681
Molecular cancer research : MCR 2024 Jul 2;22(7):668-681
Fangji Huangqi Decoction alleviates rheumatoid arthritis through regulating HIF-1α mediated the angiogenesis and the balance between autophagy and apoptosis.
Xu Y, Li S, Wang Y, Pu W, Liu Q, Zhang Y, Liu Y, Hao H
Journal of ethnopharmacology 2024 Jul 15;329:118061
Journal of ethnopharmacology 2024 Jul 15;329:118061
Exposure memory and susceptibility to ambient PM(2.5): A perspective from hepatic cholesterol and bile acid metabolism.
Zhang X, Li Z, Hu R, Liu X, Yang W, Wu Y, Zhang L, Zeng X, Chen R, Liu C, Sun Q
Ecotoxicology and environmental safety 2024 Jul 15;280:116589
Ecotoxicology and environmental safety 2024 Jul 15;280:116589
4D label-free quantitative proteomic analysis identifies CRABP1 as a novel candidate gene for litter size in rabbits†.
Bao Z, Chen Y, Li J, Cai J, Yang J, Zhai P, Zhao B, Wu X
Biology of reproduction 2024 Jul 12;111(1):110-122
Biology of reproduction 2024 Jul 12;111(1):110-122
Structural and functional insights into yeast Tbf1 as an atypical telomeric repeat-binding factor.
Wu Z, Gu X, Zha L, Yang Q, Zhou Y, Zeng Z
Structure (London, England : 1993) 2024 Jul 11;32(7):889-898.e3
Structure (London, England : 1993) 2024 Jul 11;32(7):889-898.e3
Bacillus cereus CwpFM induces colonic tissue damage and inflammatory responses through oxidative stress and the NLRP3/NF-κB pathway.
Shan Q, Wang X, Yang H, Zhu Y, Wang J, Yang G
The Science of the total environment 2024 Jul 10;933:173079
The Science of the total environment 2024 Jul 10;933:173079
AGPAT3 deficiency impairs adipocyte differentiation and leads to a lean phenotype in mice.
Zhou H, Fick K, Patel V, Hilton LR, Kim HW, Bagi Z, Weintraub NL, Chen W
American journal of physiology. Endocrinology and metabolism 2024 Jul 1;327(1):E69-E80
American journal of physiology. Endocrinology and metabolism 2024 Jul 1;327(1):E69-E80
Maternal high fat diet programs spatial learning and central leptin signaling in mouse offspring in a sex-specific manner.
Li Y, Yang Y, Ye B, Lin Y
Physiology & behavior 2024 Jul 1;281:114580
Physiology & behavior 2024 Jul 1;281:114580
Regulating effect of miR-132-3p on the changes of MAPK pathway in rat brains and SH-SY5Y cells exposed to excessive fluoride by targeting expression of MAPK1.
He WW, Zeng XX, Qi XL, Gui CZ, Liao W, Tu X, Deng J, Dong YT, Hong W, He Y, Xiao Y, Guan ZZ
Ecotoxicology and environmental safety 2024 Jul 1;279:116467
Ecotoxicology and environmental safety 2024 Jul 1;279:116467
Fibroblast growth factor 21 inhibits ferroptosis following spinal cord injury by regulating heme oxygenase-1.
Gu Q, Sha W, Huang Q, Wang J, Zhu Y, Xu T, Xu Z, Zhu Q, Ge J, Tian S, Lin X
Neural regeneration research 2024 Jul 1;19(7):1568-1574
Neural regeneration research 2024 Jul 1;19(7):1568-1574
SLC7A11 promotes EMT and metastasis in invasive pituitary neuroendocrine tumors by activating the PI3K/AKT signaling pathway.
Gui S, Yu W, Xie J, Peng L, Xiong Y, Song Z, Luo H, Xiao J, Yuan S, Cheng Z
Endocrine connections 2024 Jul 1;13(7)
Endocrine connections 2024 Jul 1;13(7)
Analysis of multiple programmed cell death-related prognostic genes and functional validations of necroptosis-associated genes in oesophageal squamous cell carcinoma.
Cao K, Zhu J, Lu M, Zhang J, Yang Y, Ling X, Zhang L, Qi C, Wei S, Zhang Y, Ma J
EBioMedicine 2024 Jan;99:104920
EBioMedicine 2024 Jan;99:104920
Multi-omics analyses reveal bacteria and catalase associated with keloid disease.
Shan M, Xiao M, Xu J, Sun W, Wang Z, Du W, Liu X, Nie M, Wang X, Liang Z, Liu H, Hao Y, Xia Y, Zhu L, Song K, Feng C, Meng T, Wang Z, Cao W, Wang L, Zheng Z, Wang Y, Huang Y
EBioMedicine 2024 Jan;99:104904
EBioMedicine 2024 Jan;99:104904
Loss of STARD13 contributes to aggressive phenotype transformation and poor prognosis in papillary thyroid carcinoma.
Zeng C, Li H, Liang W, Chen J, Zhang Y, Zhang H, Xiao H, Li Y, Guan H
Endocrine 2024 Jan;83(1):127-141
Endocrine 2024 Jan;83(1):127-141
Arsenic induced neurotoxicity in the brain of ducks: The potential involvement of the gut-brain axis.
Wu S, Zhong G, Su Q, Hu T, Rao G, Li T, Wu Y, Ruan Z, Zhang H, Tang Z, Hu L
Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS) 2024 Jan;81:127336
Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS) 2024 Jan;81:127336
Downregulation of Rab23 inhibits hepatocellular carcinoma by repressing SHH signaling pathway.
Liu SJ, Zang YW, Huang CJ, Liu YJ
Cancer reports (Hoboken, N.J.) 2024 Jan;7(1):e1921
Cancer reports (Hoboken, N.J.) 2024 Jan;7(1):e1921
pH Sensitive Quercetin Nanoparticles Ameliorate DSS-Induced Colitis in Mice by Colon-Specific Delivery.
Wang L, Fu R, Meng Y, Liang J, Xue W, Hu H, Meng J, Zhang M
Molecular nutrition & food research 2024 Jan;68(2):e2300051
Molecular nutrition & food research 2024 Jan;68(2):e2300051
circPPP2R4 promotes colorectal cancer progression and reduces ROS production through the miR-646/FOXK1 axis.
Hong Y, Chen B, Wang C, Gui R, Zhai X, Qian Q, Ren X, Xie X, Jiang C
Molecular carcinogenesis 2024 Jan;63(1):106-119
Molecular carcinogenesis 2024 Jan;63(1):106-119
Na(v)1.7 as a chondrocyte regulator and therapeutic target for osteoarthritis.
Fu W, Vasylyev D, Bi Y, Zhang M, Sun G, Khleborodova A, Huang G, Zhao L, Zhou R, Li Y, Liu S, Cai X, He W, Cui M, Zhao X, Hettinghouse A, Good J, Kim E, Strauss E, Leucht P, Schwarzkopf R, Guo EX, Samuels J, Hu W, Attur M, Waxman SG, Liu CJ
Nature 2024 Jan;625(7995):557-565
Nature 2024 Jan;625(7995):557-565
L116 Deletion in CSPα Promotes α-Synuclein Aggregation and Neurodegeneration.
Guo T, Xiong J, Feng H, Bu L, Xiao T, Zhou L, He J, Deng M, Liu Y, Zhang Z, Zhang Z
Molecular neurobiology 2024 Jan;61(1):15-27
Molecular neurobiology 2024 Jan;61(1):15-27
Tumor suppressor CLCA1 inhibits angiogenesis via TGFB1/SMAD/VEGF cascade and sensitizes hepatocellular carcinoma cells to Sorafenib.
He J, Wu F, Li J, Deng Q, Chen J, Li P, Jiang X, Yang K, Xu S, Jiang Z, Li X, Jiang Z
Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 2024 Jan;56(1):176-186
Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 2024 Jan;56(1):176-186
Comparative analyses of the Smith-Magenis syndrome protein RAI1 in mice and common marmoset monkeys.
Chang YT, Lee YJ, Haque M, Chang HC, Javed S, Lin YC, Cho Y, Abramovitz J, Chin G, Khamis A, Raja R, Murai KK, Huang WH
The Journal of comparative neurology 2024 Jan;532(1):e25589
The Journal of comparative neurology 2024 Jan;532(1):e25589
Gab2 promotes the growth of colorectal cancer by regulating the M2 polarization of tumor‑associated macrophages.
Gao X, Long R, Qin M, Zhu W, Wei L, Dong P, Chen J, Luo J, Feng J
International journal of molecular medicine 2024 Jan;53(1)
International journal of molecular medicine 2024 Jan;53(1)
IL-4/STAT6 axis observed to reverse proliferative defect in SCA3 patient-derived neural progenitor cells.
Chen FM, Li H, Chung DL, Mak ATL, Leung FP, Chan HYE, Wong WT
Clinical and experimental pharmacology & physiology 2024 Jan;51(1):30-39
Clinical and experimental pharmacology & physiology 2024 Jan;51(1):30-39
SYNPO2 promotes the development of BLCA by upregulating the infiltration of resting mast cells and increasing the resistance to immunotherapy.
Ye G, Tu L, Li Z, Li X, Zheng X, Song Y
Oncology reports 2024 Jan;51(1)
Oncology reports 2024 Jan;51(1)
ATR induces hepatic lipid metabolism disorder in rats by activating IRE1α/XBP1 signaling pathway.
Qian H, Zhao Y, Wang Y, Zhao H, Cui J, Wang Z, Ye H, Fang X, Ge Z, Zhang Y, Ye L
Toxicology 2024 Jan;501:153696
Toxicology 2024 Jan;501:153696
Lymphatic endothelial-like cells promote glioblastoma stem cell growth through cytokine-driven cholesterol metabolism.
Zhao L, Qiu Z, Yang Z, Xu L, Pearce TM, Wu Q, Yang K, Li F, Saulnier O, Fei F, Yu H, Gimple RC, Varadharajan V, Liu J, Hendrikse LD, Fong V, Wang W, Zhang J, Lv D, Lee D, Lehrich BM, Jin C, Ouyang L, Dixit D, Wu H, Wang X, Sloan AE, Wang X, Huan T, Mark Brown J, Goldman SA, Taylor MD, Zhou S, Rich JN
Nature cancer 2024 Jan;5(1):147-166
Nature cancer 2024 Jan;5(1):147-166
Hsa_circ_0001583 fuels bladder cancer metastasis by promoting staphylococcal nuclease and tudor domain containing 1-mediated MicroRNA decay.
Liu C, Cong Y, Chen L, Lv F, Cheng L, Song Y, Xing Y
Neoplasia (New York, N.Y.) 2024 Jan;47:100963
Neoplasia (New York, N.Y.) 2024 Jan;47:100963
SRSF7 is a promising prognostic biomarker in hepatocellular carcinoma and is associated with immune infiltration.
Shen W, Yuan L, Cheng F, Wu Z, Li X
Genes & genomics 2024 Jan;46(1):49-64
Genes & genomics 2024 Jan;46(1):49-64
Sirtuin 6 protects against podocyte injury by blocking the renin-angiotensin system by inhibiting the Wnt1/β-catenin pathway.
Miao H, Wang YN, Su W, Zou L, Zhuang SG, Yu XY, Liu F, Zhao YY
Acta pharmacologica Sinica 2024 Jan;45(1):137-149
Acta pharmacologica Sinica 2024 Jan;45(1):137-149
Nerolidol attenuates airway inflammation and airway remodeling and alters gut microbes in ovalbumin-induced asthmatic mice.
Wang T, Song G, Sun M, Zhang Y, Zhang B, Peng M, Li M
Cell biochemistry and function 2024 Jan;42(1):e3899
Cell biochemistry and function 2024 Jan;42(1):e3899
Leukocyte-poor platelet-rich plasma and leukocyte-rich platelet-rich plasma promote myoblast proliferation through the upregulation of cyclin A, cdk1, and cdk2.
Chen LS, Chen CK, Pang JS, Lin LP, Yu TY, Tsai WC
Journal of orthopaedic research : official publication of the Orthopaedic Research Society 2024 Jan;42(1):32-42
Journal of orthopaedic research : official publication of the Orthopaedic Research Society 2024 Jan;42(1):32-42
Mitofusin2 Ameliorated Endoplasmic Reticulum Stress and Mitochondrial Reactive Oxygen Species Through Maintaining Mitochondria-Associated Endoplasmic Reticulum Membrane Integrity in Cisplatin-Induced Acute Kidney Injury.
Liu YT, Zhang H, Duan SB, Wang JW, Chen H, Zhan M, Zhang W, Li AM, Liu Y, Yang Y, Yang S
Antioxidants & redox signaling 2024 Jan;40(1-3):16-39
Antioxidants & redox signaling 2024 Jan;40(1-3):16-39
Anti-inflammatory activities of several diterpenoids isolated from Hemionitis albofusca.
Pei X, Lou Y, Ren Q, Liu Y, Dai X, Ye M, Huang G, Cao J
Naunyn-Schmiedeberg's archives of pharmacology 2024 Jan;397(1):437-449
Naunyn-Schmiedeberg's archives of pharmacology 2024 Jan;397(1):437-449
Non-small cell lung cancer cells with uncommon EGFR exon 19delins variants respond poorly to third-generation EGFR inhibitors.
Lu Z, Yi Y, Wang L, Luo Y, Luo D, Xiong L, Shu Y, Luo H, Li J, Zhu W, Zeng Z, Liu A
Translational oncology 2024 Jan;39:101834
Translational oncology 2024 Jan;39:101834
Hsa_circ_0020134 promotes liver metastasis of colorectal cancer through the miR-183-5p-PFN2-TGF-β/Smad axis.
Yu JH, Tan JN, Zhong GY, Zhong L, Hou D, Ma S, Wang PL, Zhang ZH, Lu XQ, Yang B, Zhou SN, Han FH
Translational oncology 2024 Jan;39:101823
Translational oncology 2024 Jan;39:101823
CYB5R1 is a potential biomarker that correlates with stemness and drug resistance in gastric cancer.
Zhang Q, Ma Y, Yan Y, Zhang L, Zhang Y
Translational oncology 2024 Jan;39:101766
Translational oncology 2024 Jan;39:101766
Pro-osteogenic role of interleukin-22 in calcific aortic valve disease.
Deng H, Li H, Liu Z, Shen N, Dong N, Deng C, Liu F
Atherosclerosis 2024 Jan;388:117424
Atherosclerosis 2024 Jan;388:117424
Uric acid promotes interleukin-17 expression to cause kidney injury.
Yang L, He T, Yu Y
Journal of biochemical and molecular toxicology 2024 Jan;38(1):e23550
Journal of biochemical and molecular toxicology 2024 Jan;38(1):e23550
Advanced glycation end products induce nucleus pulposus cell apoptosis by upregulating TXNIP via inhibiting glycolysis pathway in intervertebral disc degeneration.
Chen F, Sheng X, Sun H, Guo Q, Wang H, Wu L, Ni B, Yang J
Journal of biochemical and molecular toxicology 2024 Jan;38(1):e23515
Journal of biochemical and molecular toxicology 2024 Jan;38(1):e23515
MiR-9 promotes G-MDSC recruitment and tumor proliferation by targeting SOCS3 in breast cancer.
Gu X, Wei F, Tong J, Liu Y, Chen S, Zheng L, Xing Y
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Jan;38(1):e23388
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Jan;38(1):e23388
MicroRNA-10a-5p-mediated downregulation of GATA6 inhibits tumor progression in ovarian cancer.
Gao F, Wu Q, Lu D
Human cell 2024 Jan;37(1):271-284
Human cell 2024 Jan;37(1):271-284
Injectable dexamethasone-loaded peptide hydrogel for therapy of radiation-induced ototoxicity by regulating the mTOR signaling pathway.
Liu J, Zhu L, Bao Y, Du Z, Shi L, Hong X, Zou Z, Peng G
Journal of controlled release : official journal of the Controlled Release Society 2024 Jan;365:729-743
Journal of controlled release : official journal of the Controlled Release Society 2024 Jan;365:729-743
Exposure of embryos to fenbuconazole causes persistent neurotoxicity in adult zebrafish.
Zhang Y, Tang C, Li Z, Aihaiti A, Wang C
Chemosphere 2024 Jan;347:140728
Chemosphere 2024 Jan;347:140728
PCB126 impairs human sperm functions by affecting post-translational modifications and mitochondrial functions.
Yang Y, Mei G, Yang L, Luo T, Wu R, Peng S, Peng Z, Cui J, Cheng Y
Chemosphere 2024 Jan;346:140532
Chemosphere 2024 Jan;346:140532
RNA sequencing reveals the transcriptomic landscape and alternative splicing events induced by LGALS1 silencing in non-small cell lung cancer.
Shi H, Zhang Y, Liu J, Wang Y, Fang P
Advances in clinical and experimental medicine : official organ Wroclaw Medical University 2024 Jan;33(1):79-90
Advances in clinical and experimental medicine : official organ Wroclaw Medical University 2024 Jan;33(1):79-90
IDO-1 impairs antitumor immunity of natural killer cells in triple-negative breast cancer via up-regulation of HLA-G.
Jing R, Bai S, Zhang P, Ren H, Jia L, Li W, Zheng G
Breast cancer (Tokyo, Japan) 2024 Jan;31(1):135-147
Breast cancer (Tokyo, Japan) 2024 Jan;31(1):135-147
EAAT3 impedes oligodendrocyte remyelination in chronic cerebral hypoperfusion-induced white matter injury.
Zhang Y, Ya D, Yang J, Jiang Y, Li X, Wang J, Tian N, Deng J, Yang B, Li Q, Liao R
CNS neuroscience & therapeutics 2024 Jan;30(1):e14487
CNS neuroscience & therapeutics 2024 Jan;30(1):e14487
Transcriptomics reveal a molecular signature in the progression of nonalcoholic steatohepatitis and identifies PAI‑1 and MMP‑9 as biomarkers in in vivo and in vitro studies.
Zhao Y, Yakufu M, Ma C, Wang B, Yang J, Hu J
Molecular medicine reports 2024 Jan;29(1)
Molecular medicine reports 2024 Jan;29(1)
Duck Tembusu virus infection activates the MKK3/6-p38 MAPK signaling pathway to promote virus replication.
Cheng Y, Jiao L, Chen J, Chen P, Zhou F, Zhang J, Wang M, Wu Q, Cao S, Lu H, Wu Z, Wang A, Qian Y, Zhu S
Veterinary microbiology 2024 Jan;288:109951
Veterinary microbiology 2024 Jan;288:109951
Ailanthone synergizes with PARP1 inhibitor in tumour growth inhibition through crosstalk of DNA repair pathways in gastric cancer.
Wang C, Yi T, Li X, Cui J, Li B, Qin Y, Tang S, Zhang J
Journal of cellular and molecular medicine 2024 Jan;28(2):e18033
Journal of cellular and molecular medicine 2024 Jan;28(2):e18033
Oncostatin M enhances osteoprotegerin synthesis but reduces macrophage colony‑stimulating factor synthesis in bFGF‑stimulated osteoblast‑like cells.
Hioki T, Tachi J, Ueda K, Matsushima-Nishiwaki R, Iida H, Kozawa O, Tokuda H
Experimental and therapeutic medicine 2024 Jan;27(1):34
Experimental and therapeutic medicine 2024 Jan;27(1):34
Hematoporphyrin derivative photodynamic therapy induces apoptosis and suppresses the migration of human esophageal squamous cell carcinoma cells by regulating the PI3K/AKT/mTOR signaling pathway.
Wei X, Ni J, Yuan L, Li X
Oncology letters 2024 Jan;27(1):17
Oncology letters 2024 Jan;27(1):17
Ovarian carcinoma immune-related microRNA affects the heterogeneity of the endocrine microenvironment and anti-tumor immune pattern.
Gao K, Wang Q, Xiang P, Xiong J, Xu X, Qin L, Sun X, Fan Y, Yue C
The journal of gene medicine 2024 Jan;26(1):e3602
The journal of gene medicine 2024 Jan;26(1):e3602
CircDYM attenuates microglial apoptosis via CEBPB/ZC3H4 axis in LPS-induced mouse model of depression.
Zhou Z, Ye Q, Ren H, Zhang Y, Han B, Yao H, Bai Y
International journal of biological macromolecules 2024 Jan;254(Pt 3):127922
International journal of biological macromolecules 2024 Jan;254(Pt 3):127922
Vasculogenic mimicry-associated novel gene signature predicted prognosis and response to immunotherapy in lung adenocarcinoma.
Zhang L, Wu J, Yin WW, Hu J, Liao L, Ma J, Xu Z, Wu S
Pathology, research and practice 2024 Jan;253:155048
Pathology, research and practice 2024 Jan;253:155048
Bridging integrator 1 fragment accelerates tau aggregation and propagation by enhancing clathrin-mediated endocytosis in mice.
Zhang X, Zou L, Tang L, Xiong M, Yan XX, Meng L, Chen G, Xiong J, Nie S, Zhang Z, Chen Q, Zhang Z
PLoS biology 2024 Jan;22(1):e3002470
PLoS biology 2024 Jan;22(1):e3002470
STING modulates iron metabolism to promote liver injury and inflammation in acute immune hepatitis.
Zhao J, Yi Z, Deng G, Li Y, Li J, Qin M, Wu C, Luo P, Ma S, Gao L
Free radical biology & medicine 2024 Jan;210:367-377
Free radical biology & medicine 2024 Jan;210:367-377
Melatonin attenuates sepsis-induced acute kidney injury by promoting mitophagy through SIRT3-mediated TFAM deacetylation.
Deng Z, He M, Hu H, Zhang W, Zhang Y, Ge Y, Ma T, Wu J, Li L, Sun M, An S, Li J, Huang Q, Gong S, Zhang J, Chen Z, Zeng Z
Autophagy 2024 Jan;20(1):151-165
Autophagy 2024 Jan;20(1):151-165
A proteome-wide screen identifies the calcium binding proteins, S100A8/S100A9, as clinically relevant therapeutic targets in aortic dissection.
Jiang H, Zhao Y, Su M, Sun L, Chen M, Zhang Z, Ilyas I, Wang Z, Little PJ, Wang L, Weng J, Ge J, Xu S
Pharmacological research 2024 Jan;199:107029
Pharmacological research 2024 Jan;199:107029
Overexpression of Corin Ameliorates Kidney Fibrosis through Inhibition of Wnt/β-Catenin Signaling in Mice.
Su X, Li S, Zhang Y, Tie X, Feng R, Guo X, Qiao X, Wang L
The American journal of pathology 2024 Jan;194(1):101-120
The American journal of pathology 2024 Jan;194(1):101-120
Pathologic changes in neuronal intranuclear inclusion disease are linked to aberrant FUS interaction under hyperosmotic stress.
Wang H, Zheng Y, Yu J, Meng L, Zhang W, Hong D, Wang Z, Yuan Y, Deng J
Neurobiology of disease 2024 Jan;190:106391
Neurobiology of disease 2024 Jan;190:106391
Highly efficient identification of nucleocytoplasmic O-glycosylation by the TurboID-based proximity labeling method in living cells.
Long Y, Li Z, Wang L, Ao X, Zhang Z, Chen Q, Zhu D, Liu X, Liu R, Chen B, Zhu H, Su Y
Biotechnology journal 2024 Jan;19(1):e2300090
Biotechnology journal 2024 Jan;19(1):e2300090
Photobiomodulation inhibits the expression of chondroitin sulfate proteoglycans after spinal cord injury via the Sox9 pathway.
Zhang Z, Song Z, Luo L, Zhu Z, Zuo X, Ju C, Wang X, Ma Y, Wu T, Yao Z, Zhou J, Chen B, Ding T, Wang Z, Hu X
Neural regeneration research 2024 Jan;19(1):180-189
Neural regeneration research 2024 Jan;19(1):180-189
Ambra1 in exosomes secreted by HK-2 cells damaged by supersaturated oxalate induce mitophagy and autophagy-ferroptosis in normal HK-2 cells to participate in the occurrence of kidney stones.
Su X, Song C, He Z, Song Q, Meng L, Dong C, Zhou J, Ke H, Xiong Y, Liu J, Liao W, Yang S
Biochimica et biophysica acta. Molecular cell research 2024 Jan;1871(1):119604
Biochimica et biophysica acta. Molecular cell research 2024 Jan;1871(1):119604
Dectin1 contributes to hypertensive vascular injury by promoting macrophage infiltration through activating the Syk/NF-κB pathway.
Zhang J, Tu Y, Wei J, Zheng R, Shao J, Chen Q, Liang G, Ying H, Han X, Shi Q
Biochimica et biophysica acta. Molecular basis of disease 2024 Jan;1870(1):166911
Biochimica et biophysica acta. Molecular basis of disease 2024 Jan;1870(1):166911
Melatonin inhibits fibroblast cell functions and hypertrophic scar formation by enhancing autophagy through the MT2 receptor-inhibited PI3K/Akt /mTOR signaling.
Dong Y, Cao X, Huang J, Hu Z, Chen C, Chen M, Long Q, Xu Z, Lv D, Rong Y, Luo S, Wang H, Deng W, Tang B
Biochimica et biophysica acta. Molecular basis of disease 2024 Jan;1870(1):166887
Biochimica et biophysica acta. Molecular basis of disease 2024 Jan;1870(1):166887
Lactobacillus species ameliorate membranous nephropathy through inhibiting the aryl hydrocarbon receptor pathway via tryptophan-produced indole metabolites.
Miao H, Wang YN, Yu XY, Zou L, Guo Y, Su W, Liu F, Cao G, Zhao YY
British journal of pharmacology 2024 Jan;181(1):162-179
British journal of pharmacology 2024 Jan;181(1):162-179
AhR-STAT3-HO-1/COX-2 signalling pathway may restrict ferroptosis and improve hMSC accumulation and efficacy in mouse liver.
Han L, Ma C, Wu Z, Xu H, Li H, Pan G
British journal of pharmacology 2024 Jan;181(1):125-141
British journal of pharmacology 2024 Jan;181(1):125-141
USP7 reduces the level of nuclear DICER, impairing DNA damage response and promoting cancer progression.
Liu X, Lu R, Yang Q, He J, Huang C, Cao Y, Zhou Z, Huang J, Li L, Chen R, Wang Y, Huang J, Xie R, Zhao X, Yu J
Molecular oncology 2024 Jan;18(1):170-189
Molecular oncology 2024 Jan;18(1):170-189
Osteoblast-derived exosomes promote osteogenic differentiation of osteosarcoma cells via URG4/Wnt signaling pathway.
Leng Y, Li J, Long Z, Li C, Zhang L, Huang Z, Xi J, Liu Y
Bone 2024 Jan;178:116933
Bone 2024 Jan;178:116933
Integrated transcriptomic and proteomic analysis reveals Guizhi-Fuling Wan inhibiting STAT3-EMT in ovarian cancer progression.
Ma Q, Chen F, Liu Y, Wu K, Bu Z, Qiu C, Neamati N, Lu T
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Jan;170:116016
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Jan;170:116016
Formononetin ameliorates isoproterenol induced cardiac fibrosis through improving mitochondrial dysfunction.
Qian L, Xu H, Yuan R, Yun W, Ma Y
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Jan;170:116000
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Jan;170:116000
dCas9/CRISPR-based methylation of O-6-methylguanine-DNA methyltransferase enhances chemosensitivity to temozolomide in malignant glioma.
Zapanta Rinonos S, Li T, Pianka ST, Prins TJ, Eldred BSC, Kevan BM, Liau LM, Nghiemphu PL, Cloughesy TF, Lai A
Journal of neuro-oncology 2024 Jan;166(1):129-142
Journal of neuro-oncology 2024 Jan;166(1):129-142
FAM21 interacts with Ku to promote the localization of WASH to DNA double strand break sites.
Wang T, Zheng AX, Li P, Tang T, Zhang LP, Hong Y, Hong X, Deng ZH
DNA repair 2024 Jan;133:103603
DNA repair 2024 Jan;133:103603
Helenine blocks NLRP3 activation by disrupting the NEK7-NLRP3 interaction and ameliorates inflammatory diseases.
Fang ZE, Wang Y, Bian S, Qin S, Zhao H, Wen J, Liu T, Ren L, Li Q, Shi W, Zhao J, Yang H, Peng R, Wang Q, Bai Z, Xu G
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jan;122:155159
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jan;122:155159
Reduced estrogen signaling contributes to bone loss and cardiac dysfunction in interleukin-10 knockout mice.
Alake SE, Ice J, Robinson K, Price P, Hatter B, Wozniak K, Lin D, Chowanadisai W, Smith BJ, Lucas EA
Physiological reports 2024 Jan;12(1):e15914
Physiological reports 2024 Jan;12(1):e15914
PKD knockdown mitigates Ang II-induced cardiac hypertrophy and ferroptosis via the JNK/P53 signaling pathway.
Lv C, Zhou L, Meng Y, Yuan H, Geng J
Cellular signalling 2024 Jan;113:110974
Cellular signalling 2024 Jan;113:110974
Identification and functional coordination analysis of gene co-expression networks in different tissues of XBP1 cartilage-specific deficient mice.
Li X, Pan Y, Liu K, Yang Y, Ye Y, Xu Q, Fan M, Guo F
Cellular signalling 2024 Jan;113:110929
Cellular signalling 2024 Jan;113:110929
Manganese Enhances the Osteogenic Effect of Silicon-Hydroxyapatite Nanowires by Targeting T Lymphocyte Polarization.
Li R, Zhu Z, Zhang B, Jiang T, Zhu C, Mei P, Jin Y, Wang R, Li Y, Guo W, Liu C, Xia L, Fang B
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Jan;11(4):e2305890
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Jan;11(4):e2305890
Cytoplasmic Escape of Mitochondrial DNA Mediated by Mfn2 Downregulation Promotes Microglial Activation via cGas-Sting Axis in Spinal Cord Injury.
Wei FL, Wang TF, Wang CL, Zhang ZP, Zhao JW, Heng W, Tang Z, Du MR, Yan XD, Li XX, Guo Z, Qian JX, Zhou CP
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Jan;11(4):e2305442
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Jan;11(4):e2305442
Arf1 GTPase Regulates Golgi-Dependent G2/M Transition and Spindle Organization in Oocyte Meiosis.
Zhang KH, Zou YJ, Shan MM, Pan ZN, Ju JQ, Liu JC, Ji YM, Sun SC
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Jan;11(4):e2303009
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Jan;11(4):e2303009
Ganoderic acid A slows osteoarthritis progression by attenuating endoplasmic reticulum stress and blocking NF-Κb pathway.
Liu Y, Zhou C, Tan J, Wu T, Pan C, Liu J, Cheng X
Chemical biology & drug design 2024 Jan;103(1):e14382
Chemical biology & drug design 2024 Jan;103(1):e14382
A novel lncRNA LOC105613571 binding with BDNF in pituitary promotes gonadotropin secretion by AKT/ERK-mTOR pathway in sheep associated with prolificacy.
Cai Y, Yang H, Wan Z, Chen PY, Wang ZB, Guo JJ, Wang D, Wang F, Zhang Y
BioFactors (Oxford, England) 2024 Jan-Feb;50(1):58-73
BioFactors (Oxford, England) 2024 Jan-Feb;50(1):58-73
Corydalis saxicolaBunting total alkaloid eliminates Porphyromonas gingivalis strain 33277 internalized into macrophages by inhibition of TLR2.
Yang L, Mei GC, Wu JX, Jiang QZ, Su ZH, Liao HQ, Liu ZM, Tao RC, Yong XZ
Microbes and infection 2024 Jan-Feb;26(1-2):105244
Microbes and infection 2024 Jan-Feb;26(1-2):105244
Irradiated Cell-derived Exosomes Enhance Cell Proliferation and Radioresistance via the MAPK/Erk Pathway.
Dong Y, Tamari K, Kishigami M, Katsuki S, Minami K, Tatekawa S, Shimizu S, Koizumi M, Ogawa K
Cancer genomics & proteomics 2024 Jan-Feb;21(1):12-17
Cancer genomics & proteomics 2024 Jan-Feb;21(1):12-17
Macrophage-derived exosomal miRNA-141 triggers endothelial cell pyroptosis by targeting NLRP3 to accelerate sepsis progression.
Zhan F, Zhang J, He P, Chen W, Ouyang Y
International journal of immunopathology and pharmacology 2024 Jan-Dec;38:3946320241234736
International journal of immunopathology and pharmacology 2024 Jan-Dec;38:3946320241234736
Regulation of the immune microenvironment by pioglitazone-loaded polylactic glycolic acid nanosphere composite scaffolds to promote vascularization and bone regeneration.
Fan S, Tan Y, Yuan X, Liu C, Wu X, Dai T, Ni S, Wang J, Weng Y, Zhao H
Journal of tissue engineering 2024 Jan-Dec;15:20417314241231452
Journal of tissue engineering 2024 Jan-Dec;15:20417314241231452
Enhanced Gasdermin-E-mediated Pyroptosis in Alzheimer's Disease.
Wang Q, Guo S, Hu D, Dong X, Meng Z, Jiang Y, Feng Z, Zhou W, Song W
Neuroscience 2024 Jan 9;536:1-11
Neuroscience 2024 Jan 9;536:1-11
Upregulation of TTK expression is associated with poor prognosis and immune infiltration in endometrial cancer patients.
Du H, Zhang L, Chen J, Chen X, Qiang R, Ding X, Wang Y, Yang X
Cancer cell international 2024 Jan 9;24(1):20
Cancer cell international 2024 Jan 9;24(1):20
Hepcidin deficiency impairs hippocampal neurogenesis and mediates brain atrophy and memory decline in mice.
Bai X, Wang B, Cui Y, Tian S, Zhang Y, You L, Chang YZ, Gao G
Journal of neuroinflammation 2024 Jan 9;21(1):15
Journal of neuroinflammation 2024 Jan 9;21(1):15
The role of angiotensin II activation of yes-associated protein/PDZ-binding motif signaling in hypertensive cardiac and vascular remodeling.
Xu Q, Zhuo K, Zhang X, Zhen Y, Liu L, Zhang L, Gu Y, Jia H, Chen Q, Liu M, Dong J, Zhou MS
European journal of pharmacology 2024 Jan 5;962:176252
European journal of pharmacology 2024 Jan 5;962:176252
Ovatodiolide induces autophagy-mediated cell death through the p62-Keap1-Nrf2 signaling pathway in chronic myeloid leukemia cells.
Xia Q, Xie J, Zhang J, Zhang L, Zhou Y, Zhu B, Wu Y, Yang Z, Li J
Chemico-biological interactions 2024 Jan 5;387:110819
Chemico-biological interactions 2024 Jan 5;387:110819
Excessive Mitochondrial Fission Suppresses Mucosal Repair by Impairing Butyrate Metabolism in Colonocytes.
Fu SC, Qu JY, Li LX, Yang XX, Li YQ, Zuo XL
Inflammatory bowel diseases 2024 Jan 5;30(1):114-124
Inflammatory bowel diseases 2024 Jan 5;30(1):114-124
Proteomic Analysis of the Supernatant from Bone Marrow Mesenchymal Stem Cells under High Glucose Conditions.
Li G, Wang J, Wu W, Wang M, Han X, Zhang Z, Tang C
Journal of proteome research 2024 Jan 5;23(1):344-355
Journal of proteome research 2024 Jan 5;23(1):344-355
Proteomic and Phosphoproteomic Analysis of Right Ventricular Hypertrophy in the Pulmonary Hypertension Rat Model.
Luo A, Jia Y, Hao R, Zhou X, Bao C, Yang L, Gu C, Tang H, Chu AA
Journal of proteome research 2024 Jan 5;23(1):264-276
Journal of proteome research 2024 Jan 5;23(1):264-276
ARTC1-mediated VAPB ADP-ribosylation regulates calcium homeostasis.
Ma X, Li M, Liu Y, Zhang X, Yang X, Wang Y, Li Y, Wang J, Liu X, Yan Z, Yu X, Wu C
Journal of molecular cell biology 2024 Jan 5;15(7)
Journal of molecular cell biology 2024 Jan 5;15(7)
Caveolin 1 Regulates the Tight Junctions between Sertoli Cells and Promotes the Integrity of Blood-Testis Barrier in Yak via the FAK/ERK Signaling Pathway.
Yan Q, Li T, Zhang Y, Zhao X, Wang Q, Yuan L
Animals : an open access journal from MDPI 2024 Jan 5;14(2)
Animals : an open access journal from MDPI 2024 Jan 5;14(2)
The combination of tetracyclines effectively ameliorates liver fibrosis via inhibition of EphB1/2.
Han Y, Song H, Li Y, Li R, Chen L, Gao B, Chen Y, Wang S
International immunopharmacology 2024 Jan 5;126:111261
International immunopharmacology 2024 Jan 5;126:111261
Liriodendrin exerts protective effects against chronic endometritis in rats by modulating gut microbiota composition and the arginine/nitric oxide metabolic pathway.
Cheng F, Li D, Ma X, Wang Y, Lu L, Hu B, Cui S
International immunopharmacology 2024 Jan 5;126:111235
International immunopharmacology 2024 Jan 5;126:111235
High-expressed ACAT2 predicted the poor prognosis of platinum-resistant epithelial ovarian cancer.
Wang J, Yang Z, Bai H, Zhao L, Ji J, Bin Y, Liu Y, Zhang S, Hou H, Li Q
Diagnostic pathology 2024 Jan 4;19(1):7
Diagnostic pathology 2024 Jan 4;19(1):7
TET2-mediated tumor cGAS triggers endothelial STING activation to regulate vasculature remodeling and anti-tumor immunity in liver cancer.
Lv H, Zong Q, Chen C, Lv G, Xiang W, Xing F, Jiang G, Yan B, Sun X, Ma Y, Wang L, Wu Z, Cui X, Wang H, Yang W
Nature communications 2024 Jan 4;15(1):6
Nature communications 2024 Jan 4;15(1):6
KAT8 functions in redox homeostasis and mitochondrial dynamics during mouse oocyte meiosis progression.
Wu X, Wang S, Guo Y, Song S, Zeng S
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Jan 31;38(2):e23435
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Jan 31;38(2):e23435
Folate supports IL-25-induced tuft cell expansion following enteroviral infections.
Lyu R, Wu J, He Y, You Q, Qian Y, Jiang N, Cai Y, Chen D, Wu Z
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Jan 31;38(2):e23430
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Jan 31;38(2):e23430
Treatment with sodium butyrate induces autophagy resulting in therapeutic benefits for spinocerebellar ataxia type 3.
Watchon M, Robinson KJ, Luu L, An Y, Yuan KC, Plenderleith SK, Cheng F, Don EK, Nicholson GA, Lee A, Laird AS
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Jan 31;38(2):e23429
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Jan 31;38(2):e23429
Targeting FBXO22 enhances radiosensitivity in non-small cell lung cancer by inhibiting the FOXM1/Rad51 axis.
Chen Y, Zhou Y, Feng X, Wu Z, Yang Y, Rao X, Zhou R, Meng R, Dong X, Xu S, Zhang S, Wu G, Jie X
Cell death & disease 2024 Jan 31;15(1):104
Cell death & disease 2024 Jan 31;15(1):104
Explore Key Genes and Mechanisms Involved in Colon Cancer Progression Based on Bioinformatics Analysis.
Lan Y, Yang X, Wei Y, Tian Z, Zhang L, Zhou J
Applied biochemistry and biotechnology 2024 Jan 31;
Applied biochemistry and biotechnology 2024 Jan 31;
TMT-based proteomics analysis identifies the interventional mechanisms of Qijia Rougan decoction in improving hepatic fibrosis.
Chen X, Sun X, Ji S, Yu H, Wu P
Journal of ethnopharmacology 2024 Jan 30;319(Pt 3):117334
Journal of ethnopharmacology 2024 Jan 30;319(Pt 3):117334
Kuijie decoction ameliorates ulcerative colitis by affecting intestinal barrier functions, gut microbiota, metabolic pathways and Treg/Th17 balance in mice.
Peng K, Xia S, Xiao S, Zhang M, Liao J, Yu Q
Journal of ethnopharmacology 2024 Jan 30;319(Pt 3):117316
Journal of ethnopharmacology 2024 Jan 30;319(Pt 3):117316
Mechanism of Sophorae Flavescentis Radix (Kushen) in treating NSCLC: Insights from miRNA-mRNA network analysis.
Li J, Huang Y, Xu J, Zuo H, Tang Y, Huang HY, Chen J, Lin YC, Huang HD
Journal of ethnopharmacology 2024 Jan 30;319(Pt 3):117232
Journal of ethnopharmacology 2024 Jan 30;319(Pt 3):117232
Diterpenoid WT-29 isolated from Wedelia exerted anti-inflammatory and anti-allergic activities.
Wang R, Zeng J, Chen L, Sun L, Wang Y, Xu J, He X
Journal of ethnopharmacology 2024 Jan 30;319(Pt 2):117265
Journal of ethnopharmacology 2024 Jan 30;319(Pt 2):117265
Protective effect of Huangqi-Guizhi-Wuwutang against cyclophosphamide-induced spermatogenesis dysfunction in mice by promoting steroid hormone biosynthesis.
Zhao Y, Wu J, Li X, Chen Q, Hong Z, Zheng L, Huang S, Mo P, Li C, Wang R, Guo Q, Zhang S, Chen J
Journal of ethnopharmacology 2024 Jan 30;319(Pt 2):117260
Journal of ethnopharmacology 2024 Jan 30;319(Pt 2):117260
Quercetin inhibits mesothelial-mesenchymal transition and alleviates postoperative peritoneal adhesions by blocking the TGF-β1/PI3K/AKT pathway.
Li G, Ren Y, Li E, Deng K, Qu C, Zhang J, Zhang L, Wang X, Lian J, Zhou H, Wang Z, Shen T, Li X, Jiang Z
Journal of ethnopharmacology 2024 Jan 30;319(Pt 2):117242
Journal of ethnopharmacology 2024 Jan 30;319(Pt 2):117242
Cholinergic signaling of muscarinic receptors directly involves in the neuroprotection of muscone by inducing Ca(2+) antagonism and maintaining mitochondrial function.
Shen G, Zhou Z, Guo Y, Li L, Zeng J, Wang J, Zhao J
Journal of ethnopharmacology 2024 Jan 30;319(Pt 2):117192
Journal of ethnopharmacology 2024 Jan 30;319(Pt 2):117192
Shenqu xiaoshi oral solution enhances digestive function and stabilizes the gastrointestinal microbiota of juvenile rats with infantile anorexia.
Zhao M, Xiang T, Dong Z, Liu G, Wang P, Qi X, Hao Q, Han N, Liu Z, Li S, Yin J, Zhai J
Journal of ethnopharmacology 2024 Jan 30;319(Pt 1):117112
Journal of ethnopharmacology 2024 Jan 30;319(Pt 1):117112
Chicken Interferon-Alpha and -Lambda Exhibit Antiviral Effects against Fowl Adenovirus Serotype 4 in Leghorn Male Hepatocellular Cells.
Lai J, He X, Zhang R, Zhang L, Chen L, He F, Li L, Yang L, Ren T, Xiang B
International journal of molecular sciences 2024 Jan 30;25(3)
International journal of molecular sciences 2024 Jan 30;25(3)
Tumorous IRE1α facilitates CD8(+)T cells-dependent anti-tumor immunity and improves immunotherapy efficacy in melanoma.
Yang Y, Wang S, Wang XX, Guo S, Wang H, Shi Q, Tian Y, Wang H, Zhao T, Zhang H, Zhang B, Gao T, Li C, Yi X, Guo W
Cell communication and signaling : CCS 2024 Jan 30;22(1):83
Cell communication and signaling : CCS 2024 Jan 30;22(1):83
The pathogenic role of succinate-SUCNR1: a critical function that induces renal fibrosis via M2 macrophage.
Pu M, Zhang J, Hong F, Wang Y, Zhang C, Zeng Y, Fang Z, Qi W, Yang X, Gao G, Zhou T
Cell communication and signaling : CCS 2024 Jan 30;22(1):78
Cell communication and signaling : CCS 2024 Jan 30;22(1):78
Enhanced meningeal lymphatic drainage ameliorates lipopolysaccharide-induced brain injury in aged mice.
Dong H, Dai X, Zhou Y, Shi C, Bhuiyan P, Sun Z, Li N, Jin W
Journal of neuroinflammation 2024 Jan 30;21(1):36
Journal of neuroinflammation 2024 Jan 30;21(1):36
Vitamin D-mediated tsRNA-07804 triggers mitochondrial dysfunction and suppresses non-small cell lung cancer progression by targeting CRKL.
Liang Y, Zhang X, Peng J, Liu J, Chen H, Guo S
Journal of cancer research and clinical oncology 2024 Jan 30;150(2):51
Journal of cancer research and clinical oncology 2024 Jan 30;150(2):51
A peptide from the Japanese encephalitis virus failed to induce the production of anti-N-methyl-d-aspartate receptor antibodies via molecular mimicry in mice.
Luo H, Yang J, Yang X, Han Z, Fang Z, Huang D, Gui J, Ding R, Chen H, Cheng L, Ma J, Jiang L
Heliyon 2024 Jan 30;10(2):e24700
Heliyon 2024 Jan 30;10(2):e24700
Multifunctional Fe-based coordination polymer nano-bomb modified with β-lapachone and CaO(2) for targeted tumor dual chemodynamic therapy with enhanced ferroptosis and H(2)O(2) self-supply.
Zhao P, Gong L, Chang L, Du H, Geng M, Meng S, Dai L
Journal of nanobiotechnology 2024 Jan 3;22(1):3
Journal of nanobiotechnology 2024 Jan 3;22(1):3
Sophocarpine alleviates doxorubicin-induced heart injury by suppressing oxidative stress and apoptosis.
Zhang HJ, Fu Y, Zhang H, Lai ZQ, Dong YF
Scientific reports 2024 Jan 3;14(1):428
Scientific reports 2024 Jan 3;14(1):428
Inhibition of heme oxygenase 1 alleviates thoracic aortic aneurysm via restoration of extracellular matrix.
Song W, Shen K, Fu G, Qin L, Bagaber G, Chen J, Wei L
Biochemical and biophysical research communications 2024 Jan 29;694:149405
Biochemical and biophysical research communications 2024 Jan 29;694:149405
Schizandrin A attenuates early brain injury following subarachnoid hemorrhage through suppressing neuroinflammation.
Jin J, Chen M, Wang H, Li S, Ma L, Wang B
Molecular biology reports 2024 Jan 29;51(1):236
Molecular biology reports 2024 Jan 29;51(1):236
FBW7/GSK3β mediated degradation of IGF2BP2 inhibits IGF2BP2-SLC7A5 positive feedback loop and radioresistance in lung cancer.
Zhou Z, Zhang B, Deng Y, Deng S, Li J, Wei W, Wang Y, Wang J, Feng Z, Che M, Yang X, Meng J, Li Y, Hu Y, Sun Y, Wen L, Huang F, Sheng Y, Wan C, Yang K
Journal of experimental & clinical cancer research : CR 2024 Jan 29;43(1):34
Journal of experimental & clinical cancer research : CR 2024 Jan 29;43(1):34
Circ-phkb promotes cell apoptosis and inflammation in LPS-induced alveolar macrophages via the TLR4/MyD88/NF-kB/CCL2 axis.
Wei X, Yi X, Liu J, Sui X, Li L, Li M, Lv H, Yi H
Respiratory research 2024 Jan 29;25(1):62
Respiratory research 2024 Jan 29;25(1):62
Dopamine modification of glycolytic enzymes impairs glycolysis: possible implications for Parkinson's disease.
Chen B, Zhang Q, Zhong X, Zhang X, Liu X, Wang H, Yang F, Zhang J, Huang J, Wong YK, Luo P, Wang J, Sun J
Cell communication and signaling : CCS 2024 Jan 29;22(1):75
Cell communication and signaling : CCS 2024 Jan 29;22(1):75
Sesamin-mediated high expression of BECN2 ameliorates cartilage endplate degeneration by reducing autophagy and inflammation.
Zhang B, He Z, Guo J, Li F, Huang Z, Zheng W, Xing W, Li M, Zhu Y, Yang X
Aging 2024 Jan 26;16(2):1145-1160
Aging 2024 Jan 26;16(2):1145-1160
UBR5 promotes antiviral immunity by disengaging the transcriptional brake on RIG-I like receptors.
Yang D, Geng T, Harrison AG, Cahoon JG, Xing J, Jiao B, Wang M, Cheng C, Hill RE, Wang H, Vella AT, Cheng G, Wang Y, Wang P
Nature communications 2024 Jan 26;15(1):780
Nature communications 2024 Jan 26;15(1):780
Endoplasmic reticulum stress caused by traumatic injury promotes cardiomyocyte apoptosis through acetylation modification of GRP78.
Yan Z, Liu Y, Yang B, Zhao W, Wang Y, Wang D, Li J, Jiao X, Cao J
Acta biochimica et biophysica Sinica 2024 Jan 25;56(1):96-105
Acta biochimica et biophysica Sinica 2024 Jan 25;56(1):96-105
Melatonin alleviates valproic acid-induced neural tube defects by modulating Src/PI3K/ERK signaling and oxidative stress.
Liang Y, Wang Y, Zhang X, Jin S, Guo Y, Yu Z, Xu X, Shuai Q, Feng Z, Chen B, Liang T, Ao R, Li J, Zhang J, Cao R, Zhao H, Chen Z, Liu Z, Xie J
Acta biochimica et biophysica Sinica 2024 Jan 25;56(1):23-33
Acta biochimica et biophysica Sinica 2024 Jan 25;56(1):23-33
Molecular mechanism of specific DNA sequence recognition by NRF1.
Liu K, Li W, Xiao Y, Lei M, Zhang M, Min J
Nucleic acids research 2024 Jan 25;52(2):953-966
Nucleic acids research 2024 Jan 25;52(2):953-966
Prognosis and immunotherapy response prediction based on M2 macrophage-related genes in colon cancer.
Xu X, Zhang X, Kou R, Liu Y, Chen S, Li Z, Jian Z, Wang Z
Journal of cancer research and clinical oncology 2024 Jan 25;150(2):31
Journal of cancer research and clinical oncology 2024 Jan 25;150(2):31
Irisin mitigates rheumatoid arthritis by suppressing mitochondrial fission via inhibiting YAP-Drp1 signaling pathway.
Yu Y, Ma M, Li C, Dang Q, Lei H, Wang G, Su J, Li Y
International immunopharmacology 2024 Jan 25;127:111443
International immunopharmacology 2024 Jan 25;127:111443
The improvement of homocysteine-induced myocardial inflammation by vitamin D depends on activation of NFE2L2 mediated MTHFR.
Liu N, Su H, Lou Y, Kong J
International immunopharmacology 2024 Jan 25;127:111437
International immunopharmacology 2024 Jan 25;127:111437
Monotropein induces autophagy through activation of the NRF2/PINK axis, thereby alleviating sepsis-induced colonic injury.
Qiang J, Yang R, Li X, Xu X, Zhou M, Ji X, Lu Y, Dong Z
International immunopharmacology 2024 Jan 25;127:111432
International immunopharmacology 2024 Jan 25;127:111432
Liensinine alleviates mouse intestinal injury induced by sepsis through inhibition of oxidative stress, inflammation, and cell apoptosis.
Wang G, Ma F, Xie K, Li X, Tan X, Xia Y, Wang Y, Dong J
International immunopharmacology 2024 Jan 25;127:111335
International immunopharmacology 2024 Jan 25;127:111335
Simultaneous inhibition of FAK and ROS1 synergistically repressed triple-negative breast cancer by upregulating p53 signalling.
Tan X, Kong D, Tao Z, Cheng F, Zhang B, Wang Z, Mei Q, Chen C, Wu K
Biomarker research 2024 Jan 25;12(1):13
Biomarker research 2024 Jan 25;12(1):13
TonEBP: A Key Transcription Factor in Microglia Following Intracerebral Hemorrhage Induced-Neuroinflammation.
Palahati A, Luo Y, Qin L, Duan Y, Zhang M, Gan H, Zhai X
International journal of molecular sciences 2024 Jan 24;25(3)
International journal of molecular sciences 2024 Jan 24;25(3)
Ganoderma lucidum polysaccharide ameliorates cholesterol gallstone formation by modulating cholesterol and bile acid metabolism in an FXR-dependent manner.
Huang D, Shen S, Zhuang Q, Ye X, Qian Y, Dong Z, Wan X
Chinese medicine 2024 Jan 24;19(1):16
Chinese medicine 2024 Jan 24;19(1):16
Investigation of Tongxie-Yaofang formula in treating ulcerative colitis based on network pharmacology via regulating MAPK/AKT signaling pathway.
Liu X, Ye M, He Y, Lai Q, Liu B, Zhang L
Aging 2024 Jan 24;16(2):1911-1924
Aging 2024 Jan 24;16(2):1911-1924
Scinderin promotes glioma cell migration and invasion via remodeling actin cytoskeleton.
Lin X, Zhao Z, Sun SP, Liu W
World journal of clinical oncology 2024 Jan 24;15(1):32-44
World journal of clinical oncology 2024 Jan 24;15(1):32-44
LncRNA HOTAIR regulates autophagy and proliferation mechanisms in premature ovarian insufficiency through the miR-148b-3p/ATG14 axis.
Luo C, Wei L, Qian F, Bo L, Gao S, Yang G, Mao C
Cell death discovery 2024 Jan 24;10(1):44
Cell death discovery 2024 Jan 24;10(1):44
Integrin β1-rich extracellular vesicles of kidney recruit Fn1+ macrophages to aggravate ischemia-reperfusion-induced inflammation.
Wang W, Ren X, Chen X, Hong Q, Cai G
JCI insight 2024 Jan 23;9(2)
JCI insight 2024 Jan 23;9(2)
HIF-2α/LINC02609/APOL1-mediated lipid storage promotes endoplasmic reticulum homeostasis and regulates tumor progression in clear-cell renal cell carcinoma.
Xiao H, Qu Y, Li H, Zhang Y, Fei M, Liang C, Yang H, Zhang X
Journal of experimental & clinical cancer research : CR 2024 Jan 23;43(1):29
Journal of experimental & clinical cancer research : CR 2024 Jan 23;43(1):29
Stabilization of KPNB1 by deubiquitinase USP7 promotes glioblastoma progression through the YBX1-NLGN3 axis.
Li J, Zhang B, Feng Z, An D, Zhou Z, Wan C, Hu Y, Sun Y, Wang Y, Liu X, Wei W, Yang X, Meng J, Che M, Sheng Y, Wu B, Wen L, Huang F, Li Y, Yang K
Journal of experimental & clinical cancer research : CR 2024 Jan 23;43(1):28
Journal of experimental & clinical cancer research : CR 2024 Jan 23;43(1):28
NEIL1 drives the initiation of colorectal cancer through transcriptional regulation of COL17A1.
Cao JH, Cao CH, Lin JL, Li SY, He LJ, Han K, Chen JW, Li S, Wang X, Xie D, Wang FW
Cell reports 2024 Jan 23;43(1):113654
Cell reports 2024 Jan 23;43(1):113654
Cyclic increase in the ADAMTS1-L1CAM-EGFR axis promotes the EMT and cervical lymph node metastasis of oral squamous cell carcinoma.
Chien MH, Yang YC, Ho KH, Ding YF, Chen LH, Chiu WK, Chen JQ, Tung MC, Hsiao M, Lee WJ
Cell death & disease 2024 Jan 23;15(1):82
Cell death & disease 2024 Jan 23;15(1):82
AKT1 phosphorylation of cytoplasmic ME2 induces a metabolic switch to glycolysis for tumorigenesis.
Chen T, Xie S, Cheng J, Zhao Q, Wu H, Jiang P, Du W
Nature communications 2024 Jan 23;15(1):686
Nature communications 2024 Jan 23;15(1):686
Exogenous carbon monoxide promotes GPX4-dependent ferroptosis through ROS/GSK3β axis in non-small cell lung cancer.
Cao W, Sun M, Yu KN, Zhao L, Feng Y, Tan C, Yang M, Wang Y, Zhu F, Chen L, Nie L, Zhao Y, Chen G, Han W
Cell death discovery 2024 Jan 23;10(1):42
Cell death discovery 2024 Jan 23;10(1):42
Investigating the therapeutic effects and mechanisms of Roxadustat on peritoneal fibrosis Based on the TGF-β/Smad pathway.
Wang L, Fan J, Yang T, Shen J, Wang L, Ge W
Biochemical and biophysical research communications 2024 Jan 22;693:149387
Biochemical and biophysical research communications 2024 Jan 22;693:149387
Self-assembled coating with a metal-polyphenolic network for intraocular lens modification to prevent posterior capsule opacification.
Wang Y, Wen C, Jing R, Yang Y, Qin Y, Qi T, Hu C, Bai X, Wu C, Pei C
Biomedical materials (Bristol, England) 2024 Jan 22;19(2)
Biomedical materials (Bristol, England) 2024 Jan 22;19(2)
YAP represses intestinal inflammation through epigenetic silencing of JMJD3.
Zhu H, Lu J, Fu M, Chen P, Yu Y, Chen M, Zhao Q, Wu M, Ye M
Clinical epigenetics 2024 Jan 20;16(1):14
Clinical epigenetics 2024 Jan 20;16(1):14
DNA polymerase beta connects tumorigenicity with the circadian clock in liver cancer through the epigenetic demethylation of Per1.
Chen S, Zhang W, Li X, Cao Z, Liu C
Cell death & disease 2024 Jan 20;15(1):78
Cell death & disease 2024 Jan 20;15(1):78
LDLR is used as a cell entry receptor by multiple alphaviruses.
Zhai X, Li X, Veit M, Wang N, Wang Y, Merits A, Jiang Z, Qin Y, Zhang X, Qi K, Jiao H, He WT, Chen Y, Mao Y, Su S
Nature communications 2024 Jan 20;15(1):622
Nature communications 2024 Jan 20;15(1):622
Single-Cell Transcriptomic Sequencing Reveals Tissue Architecture and Deciphers Pathological Reprogramming During Retinal Ischemia in Macaca fascicularis.
Li L, Zuo S, Liu Y, Yang L, Ge S, Ye F, Chai P, Lu L
Investigative ophthalmology & visual science 2024 Jan 2;65(1):27
Investigative ophthalmology & visual science 2024 Jan 2;65(1):27
microRNA-622 upregulates cell cycle process by targeting FOLR2 to promote CRC proliferation.
Chen Y, Liu F, Chen X, Li W, Li K, Cai H, Wang S, Wang H, Xu K, Zhang C, Ye S, Shen Y, Mou T, Cai S, Zhou J, Yu J
BMC cancer 2024 Jan 2;24(1):26
BMC cancer 2024 Jan 2;24(1):26
Development and validation of a disulfidptosis and disulfide metabolism-related risk index for predicting prognosis in lung adenocarcinoma.
Zhong L, Chang W, Luo B, Gao W, He H, Fang M, Li H, Wen Z, Chen Y
Cancer cell international 2024 Jan 2;24(1):2
Cancer cell international 2024 Jan 2;24(1):2
SP4 Facilitates Esophageal Squamous Cell Carcinoma Progression by Activating PHF14 Transcription and Wnt/Β-Catenin Signaling.
Wei L, Deng C, Zhang B, Wang G, Meng Y, Qin H
Molecular cancer research : MCR 2024 Jan 2;22(1):55-69
Molecular cancer research : MCR 2024 Jan 2;22(1):55-69
NET1 is a critical regulator of spindle assembly and actin dynamics in mouse oocytes.
Wang S, Wu X, Zhang M, Chang S, Guo Y, Song S, Dai S, Wu K, Zeng S
Reproductive biology and endocrinology : RB&E 2024 Jan 2;22(1):5
Reproductive biology and endocrinology : RB&E 2024 Jan 2;22(1):5
Function and mechanism of GBP1 in the development and progression of cervical cancer.
Wang S, Zhang Y, Ma X, Feng Y
Journal of translational medicine 2024 Jan 2;22(1):11
Journal of translational medicine 2024 Jan 2;22(1):11
D-mannose promotes the degradation of IDH2 through upregulation of RNF185 and suppresses breast cancer.
Zhang R, Tian Z, Xu Y, Lv L
Nutrition & metabolism 2024 Jan 2;21(1):5
Nutrition & metabolism 2024 Jan 2;21(1):5
The oncogenic role and regulatory mechanism of PGK1 in human non-small cell lung cancer.
Tian T, Leng Y, Tang B, Dong X, Ren Q, Liang J, Liu T, Liu Y, Feng W, Liu S, Zhou Y, Zhao H, Shen L
Biology direct 2024 Jan 2;19(1):1
Biology direct 2024 Jan 2;19(1):1
Pharmaceutical targeting of OTUB2 sensitizes tumors to cytotoxic T cells via degradation of PD-L1.
Ren W, Xu Z, Chang Y, Ju F, Wu H, Liang Z, Zhao M, Wang N, Lin Y, Xu C, Chen S, Rao Y, Lin C, Yang J, Liu P, Zhang J, Huang C, Xia N
Nature communications 2024 Jan 2;15(1):9
Nature communications 2024 Jan 2;15(1):9
FOXP3(+) regulatory T cell perturbation mediated by the IFNγ-STAT1-IFITM3 feedback loop is essential for anti-tumor immunity.
Liu X, Zhang W, Han Y, Cheng H, Liu Q, Ke S, Zhu F, Lu Y, Dai X, Wang C, Huang G, Su B, Zou Q, Li H, Zhao W, Xiao L, Lu L, Tong X, Pan F, Li H, Li B
Nature communications 2024 Jan 2;15(1):122
Nature communications 2024 Jan 2;15(1):122
IL-21-armored B7H3 CAR-iNKT cells exert potent antitumor effects.
Liu Y, Dang Y, Zhang C, Liu L, Cai W, Li L, Fang L, Wang M, Xu S, Wang G, Zheng J, Li H
iScience 2024 Jan 19;27(1):108597
iScience 2024 Jan 19;27(1):108597
Targeted Protein Degradation through Recruitment of the CUL4 Complex Adaptor Protein DDB1.
Meyers M, Cismoski S, Panidapu A, Chie-Leon B, Nomura DK
ACS chemical biology 2024 Jan 19;19(1):58-68
ACS chemical biology 2024 Jan 19;19(1):58-68
Two mitochondrial DNA polymorphisms modulate cardiolipin binding and lead to synthetic lethality.
Chiang ACY, Ježek J, Mu P, Di Y, Klucnika A, Jabůrek M, Ježek P, Ma H
Nature communications 2024 Jan 19;15(1):611
Nature communications 2024 Jan 19;15(1):611
The CUL5 E3 ligase complex negatively regulates central signaling pathways in CD8(+) T cells.
Liao X, Li W, Zhou H, Rajendran BK, Li A, Ren J, Luan Y, Calderwood DA, Turk B, Tang W, Liu Y, Wu D
Nature communications 2024 Jan 19;15(1):603
Nature communications 2024 Jan 19;15(1):603
Macrophage-expressed SRA ameliorates alcohol-induced liver injury by suppressing S-glutathionylation of Notch1 via recruiting thioredoxin.
Li L, Luo J, Zhu Z, Wang P, Xu Q, Chang B, Wang D, Yu L, Lu X, Zhou J, Chen Q, Zuo D
Journal of leukocyte biology 2024 Jan 19;115(2):322-333
Journal of leukocyte biology 2024 Jan 19;115(2):322-333
LINC00571 drives tricarboxylic acid cycle metabolism in triple-negative breast cancer through HNRNPK/ILF2/IDH2 axis.
Xi Z, Huang H, Hu J, Yu Y, Ma X, Xu M, Ming J, Li L, Zhang H, Chen H, Huang T
Journal of experimental & clinical cancer research : CR 2024 Jan 18;43(1):22
Journal of experimental & clinical cancer research : CR 2024 Jan 18;43(1):22
Revealing the mechanism of 755-nm long-pulsed alexandrite laser in inhibiting infantile hemangioma endothelial cells through transcriptome sequencing.
Ke C, Chen C, Yang M, Chen H, Li L, Ke Y
Lasers in medical science 2024 Jan 18;39(1):37
Lasers in medical science 2024 Jan 18;39(1):37
APOE3ch alters microglial response and suppresses Aβ-induced tau seeding and spread.
Chen Y, Song S, Parhizkar S, Lord J, Zhu Y, Strickland MR, Wang C, Park J, Tabor GT, Jiang H, Li K, Davis AA, Yuede CM, Colonna M, Ulrich JD, Holtzman DM
Cell 2024 Jan 18;187(2):428-445.e20
Cell 2024 Jan 18;187(2):428-445.e20
Metabolic regulation of homologous recombination repair by MRE11 lactylation.
Chen Y, Wu J, Zhai L, Zhang T, Yin H, Gao H, Zhao F, Wang Z, Yang X, Jin M, Huang B, Ding X, Li R, Yang J, He Y, Wang Q, Wang W, Kloeber JA, Li Y, Hao B, Zhang Y, Wang J, Tan M, Li K, Wang P, Lou Z, Yuan J
Cell 2024 Jan 18;187(2):294-311.e21
Cell 2024 Jan 18;187(2):294-311.e21
METTL3 drives NSCLC metastasis by enhancing CYP19A1 translation and oestrogen synthesis.
Meng W, Xiao H, Zhao R, Chen J, Wang Y, Mei P, Li H, Liao Y
Cell & bioscience 2024 Jan 18;14(1):10
Cell & bioscience 2024 Jan 18;14(1):10
Identification of a basement membrane gene signature for predicting prognosis and estimating the tumor immune microenvironment in prostate cancer.
Xie T, Fu DJ, Li KJ, Guo JD, Xiao ZM, Li Z, Zhao SC
Aging 2024 Jan 17;16(2):1581-1604
Aging 2024 Jan 17;16(2):1581-1604
Long non-coding RNA MEG3 acts as a suppressor in breast cancer by regulating miR-330/CNN1.
Yi D, Wang Z, Yang H, Wang R, Shi X, Liu Z, Xu F, Lu Q, Chu X, Sang J
Aging 2024 Jan 17;16(2):1318-1335
Aging 2024 Jan 17;16(2):1318-1335
Heliox Protects SH-SY5Y Cells from Oxygen-Glucose Deprivation/Reperfusion-Induced Ferroptosis.
Yu S, Xiong W, Xu W, Chen Y
Journal of integrative neuroscience 2024 Jan 16;23(1):14
Journal of integrative neuroscience 2024 Jan 16;23(1):14
MicroRNA-218-5p-Ddx41 axis restrains microglia-mediated neuroinflammation through downregulating type I interferon response in a mouse model of Parkinson's disease.
Wang D, Gao H, Qin Q, Li J, Zhao J, Qu Y, Li J, Xiong Y, Min Z, Mao Z, Xue Z
Journal of translational medicine 2024 Jan 16;22(1):63
Journal of translational medicine 2024 Jan 16;22(1):63
Lifespan Effects of Muscle-Specific Androgen Receptor Overexpression on Body Composition of Male and Female Rats.
Barsky ST, Monks DA
Endocrinology 2024 Jan 16;165(3)
Endocrinology 2024 Jan 16;165(3)
HOOK3 suppresses proliferation and metastasis in gastric cancer via the SP1/VEGFA axis.
Yang K, Li J, Zhu J, Chen Y, He Y, Wang J, Shen K, Wang K, Shi T, Chen W
Cell death discovery 2024 Jan 16;10(1):33
Cell death discovery 2024 Jan 16;10(1):33
Cyanidin-3-O-glucoside and its derivative vitisin A alleviate androgenetic alopecia by exerting anti-androgen effect and inhibiting dermal papilla cell apoptosis.
Hu X, Li X, Wu S, Jiang X, Chen G, Hu Y, Sun J, Bai W
European journal of pharmacology 2024 Jan 15;963:176237
European journal of pharmacology 2024 Jan 15;963:176237
Amiloride alleviates morphine tolerance by suppressing ASIC3-dependent neuroinflammation in the spinal cord.
Gei L, Yan Y, Xing W, Li Q, Chen X, Yan F, Wang Y, Cao Y, Jiang W, E R, Luo D, Zhang Y, Zeng W, Chen D
European journal of pharmacology 2024 Jan 15;963:176173
European journal of pharmacology 2024 Jan 15;963:176173
Detrimental Role of CXCR3 in α-Naphthylisothiocyanate- and Triptolide-Induced Cholestatic Liver Injury.
Mei Y, Li X, He C, Zhang Y, Kong W, Xue R, Huang X, Shi Y, Tao G, Xing M, Wang X
Chemical research in toxicology 2024 Jan 15;37(1):42-56
Chemical research in toxicology 2024 Jan 15;37(1):42-56
Detection of glucose transporter 1 in living cells for assessment of tumor development and therapy using an electrochemical biosensor.
Wang K, Zhang C, Zhou H, Wei H, Yin L, Zhang T, Zhi Y, Zhou J, Han B, Zhang Z, Du X
Biosensors & bioelectronics 2024 Jan 15;244:115820
Biosensors & bioelectronics 2024 Jan 15;244:115820
Electroacupuncture ameliorates cognitive impairment in APP/PS1 mouse by modulating TFEB levels to relieve ALP dysfunction.
Chen H, Yang X, Gao Y, Jiang H, Guo M, Zhou Y, Li C, Tan Y, Zhang Y, Xue W
Brain research 2024 Jan 15;1823:148683
Brain research 2024 Jan 15;1823:148683
Remote modulation of WWOX by an intronic variant associated with survival of Chinese gastric cancer patients.
Cheng L, Chang Y, Xia Z, Liu Y, Liu X, Xiong L, Liu C, Zhu X, Wang M, Qiu L
International journal of cancer 2024 Jan 15;154(2):307-319
International journal of cancer 2024 Jan 15;154(2):307-319
Construction of a Novel Damage-Associated Molecular-Pattern-Related Signature to Assess Lung Adenocarcinoma's Prognosis and Immune Landscape.
Liu X, Yao S, Feng Y, Li P, Li Y, Xia S
Biomolecules 2024 Jan 15;14(1)
Biomolecules 2024 Jan 15;14(1)
MicroRNA-146a-loaded magnesium silicate nanospheres promote bone regeneration in an inflammatory microenvironment.
Yang J, Shuai J, Siow L, Lu J, Sun M, An W, Yu M, Wang B, Chen Q
Bone research 2024 Jan 15;12(1):2
Bone research 2024 Jan 15;12(1):2
Nitidine chloride inhibits G2/M phase by regulating the p53/14-3-3 Sigma/CDK1 axis for hepatocellular carcinoma treatment.
Zhang B, Zhou B, Huang G, Huang J, Lin X, Li Z, Lian Y, Huang Q, Ye Y
Heliyon 2024 Jan 15;10(1):e24012
Heliyon 2024 Jan 15;10(1):e24012
ANP32B promotes colorectal cancer cell progression and reduces cell sensitivity to PRAP1 inhibitor through up-regulating HPF1.
Yang LL, Li M, Huang W, Ren PT, Yan QH, Hao YH
Heliyon 2024 Jan 15;10(1):e23829
Heliyon 2024 Jan 15;10(1):e23829
ERRα regulates synaptic transmission through reactive oxygen species in hippocampal neurons.
Xu DM, Zhang ZJ, Guo HK, Chen GJ, Ma YL
Heliyon 2024 Jan 15;10(1):e23739
Heliyon 2024 Jan 15;10(1):e23739
Jianpi Yangxue Qufeng compound alleviates atopic dermatitis via TLR4/MyD88/NF-κB signaling pathway.
Yang X, Wang Z, Huang H, Luo G, Cong L, Yang J, Ye J
Heliyon 2024 Jan 15;10(1):e23278
Heliyon 2024 Jan 15;10(1):e23278
Glutamatergic neuronal activity regulates angiogenesis and blood-retinal barrier maturation via Norrin/β-catenin signaling.
Biswas S, Shahriar S, Bachay G, Arvanitis P, Jamoul D, Brunken WJ, Agalliu D
bioRxiv : the preprint server for biology 2024 Jan 15;
bioRxiv : the preprint server for biology 2024 Jan 15;
Bruceine B Displays Potent Antimyeloma Activity by Inducing the Degradation of the Transcription Factor c-Maf.
Li H, Zhu X, Sun Z, Wang Q, Song S, Xu Y, He G, Mao X
ACS pharmacology & translational science 2024 Jan 12;7(1):176-185
ACS pharmacology & translational science 2024 Jan 12;7(1):176-185
Downregulation of PTPRT elevates the expression of survivin and promotes the proliferation, migration, and invasion of lung adenocarcinoma.
Chen C, Liu H, Li Y, Xu Q, Liu J
BMC cancer 2024 Jan 12;24(1):63
BMC cancer 2024 Jan 12;24(1):63
Epigenetic addition of m(5)C to HBV transcripts promotes viral replication and evasion of innate antiviral responses.
Ding S, Liu H, Liu L, Ma L, Chen Z, Zhu M, Liu L, Zhang X, Hao H, Zuo L, Yang J, Wu X, Zhou P, Huang F, Zhu F, Guan W
Cell death & disease 2024 Jan 12;15(1):39
Cell death & disease 2024 Jan 12;15(1):39
Identification of important genes related to HVSMC proliferation and migration in graft restenosis based on WGCNA.
Liu X, Qin M, Chen Q, Jiang N, Wang L, Bai Y, Guo Z
Scientific reports 2024 Jan 12;14(1):1237
Scientific reports 2024 Jan 12;14(1):1237
Targeting pyroptosis with nanoparticles to alleviate neuroinflammatory for preventing secondary damage following traumatic brain injury.
Zhang X, Huang X, Hang D, Jin J, Li S, Zhu Y, Liu H
Science advances 2024 Jan 12;10(2):eadj4260
Science advances 2024 Jan 12;10(2):eadj4260
Surface characteristics and in vitro biocompatibility of titanium preserved in a vitamin C-containing saline storage solution.
Zhang WS, Liu Y, Shao SY, Shu CQ, Zhou YH, Zhang SM, Qiu J
Journal of materials science. Materials in medicine 2024 Jan 11;35(1):3
Journal of materials science. Materials in medicine 2024 Jan 11;35(1):3
Loss of Function of the Retinoblastoma Gene Affects Gap Junctional Intercellular Communication and Cell Fate in Osteoblasts.
Pendleton E, Ketner A, Ransick P, Ardekani D, Bodenstine T, Chandar N
Biology 2024 Jan 11;13(1)
Biology 2024 Jan 11;13(1)
miR-26a exerts broad-spectrum antiviral effects via the enhancement of RIG-I-mediated type I interferon response by targeting USP15.
Zhang J, Li C, Hou Y, Liu D, Li Q, Wang Z, Tang R, Zheng K, Guo H, Wang W
Microbiology spectrum 2024 Jan 11;12(1):e0312423
Microbiology spectrum 2024 Jan 11;12(1):e0312423
A conformational selection mechanism of flavivirus NS5 for species-specific STAT2 inhibition.
Biswal M, Yao W, Lu J, Chen J, Morrison J, Hai R, Song J
Communications biology 2024 Jan 10;7(1):76
Communications biology 2024 Jan 10;7(1):76
Network pharmacology and experimental validation on yangjing zhongyu decoction against diminished ovarian reserve.
Liu J, Wei B, Ma Q, Shi D, Pan X, Liu Z, Li J, Zhao P
Journal of ethnopharmacology 2024 Jan 10;318(Pt B):117023
Journal of ethnopharmacology 2024 Jan 10;318(Pt B):117023
Tumor-associated macrophage-derived exosomal miR-513b-5p is a target of jianpi yangzheng decoction for inhibiting gastric cancer.
Zhang R, Chen X, Miao C, Chen Y, Li Y, Shen J, Yuan M, Chen M, Cheng J, Liu S, Sun Q, Wu J
Journal of ethnopharmacology 2024 Jan 10;318(Pt B):117013
Journal of ethnopharmacology 2024 Jan 10;318(Pt B):117013
Fuzheng Huayu recipe alleviates liver fibrosis via inhibiting NLRP3 inflammasome activation in macrophages.
Ping D, Qi J, Li M, Sun X, Peng Y, Liu C
Journal of ethnopharmacology 2024 Jan 10;318(Pt B):117001
Journal of ethnopharmacology 2024 Jan 10;318(Pt B):117001
Inhibitory effect of Lonicera japonica-derived exosomal miR2911 on human papilloma virus.
Chi Y, Shi L, Lu S, Cui H, Zha W, Shan L, Shen Y
Journal of ethnopharmacology 2024 Jan 10;318(Pt B):116969
Journal of ethnopharmacology 2024 Jan 10;318(Pt B):116969
Lobelia chinensis Lour inhibits the progression of hepatocellular carcinoma via the regulation of the PTEN/AKT signaling pathway in vivo and in vitro.
Luo J, Chen QX, Li P, Yu H, Yu L, Lu JL, Yin HZ, Huang BJ, Zhang SJ
Journal of ethnopharmacology 2024 Jan 10;318(Pt A):116886
Journal of ethnopharmacology 2024 Jan 10;318(Pt A):116886
Hepatoprotective efficacy and interventional mechanism of JianPi LiShi YangGan formula in acute-on-chronic liver failure.
Li J, Huang Q, Ma W, Yi J, Zhong X, Hu R, Sun J, Ma M, Lv M, Han Z, Zhang W, Feng W, Sun X, Zhou X
Journal of ethnopharmacology 2024 Jan 10;318(Pt A):116880
Journal of ethnopharmacology 2024 Jan 10;318(Pt A):116880
Yang-Xin-Shu-Mai granule alleviates atherosclerosis by regulating macrophage polarization via the TLR9/MyD88/NF-κB signaling pathway.
Huang H, Sun Z, Xu J, Wang L, Zhao J, Li J, Zhang S, Yuan F, Liu M, Fang Z
Journal of ethnopharmacology 2024 Jan 10;318(Pt A):116868
Journal of ethnopharmacology 2024 Jan 10;318(Pt A):116868
Astragalus saponins protect against extrahepatic and intrahepatic cholestatic liver fibrosis models by activation of farnesoid X receptor.
Zhang L, Shi J, Shen Q, Fu Y, Qi S, Wu J, Chen J, Zhang H, Mu Y, Chen G, Liu P, Liu W
Journal of ethnopharmacology 2024 Jan 10;318(Pt A):116833
Journal of ethnopharmacology 2024 Jan 10;318(Pt A):116833
PRMT3 methylates HIF-1α to enhance the vascular calcification induced by chronic kidney disease.
Zhou G, Zhang C, Peng H, Su X, Huang Q, Zhao Z, Zhao G
Molecular medicine (Cambridge, Mass.) 2024 Jan 10;30(1):8
Molecular medicine (Cambridge, Mass.) 2024 Jan 10;30(1):8
Alamandine attenuates ovariectomy-induced osteoporosis by promoting osteogenic differentiation via AMPK/eNOS axis.
Luo W, Yao C, Sun J, Zhang B, Chen H, Miao J, Zhang Y
BMC musculoskeletal disorders 2024 Jan 10;25(1):45
BMC musculoskeletal disorders 2024 Jan 10;25(1):45
ErZhiTianGui Decoction alleviates age-related ovarian aging by regulating mitochondrial homeostasis and inhibiting ferroptosis.
Zhicheng J, Yongqian L, Peixuan W, Kai Y, Mengyu S, Wen C, Qihui L, Ying G
Journal of ovarian research 2024 Jan 10;17(1):12
Journal of ovarian research 2024 Jan 10;17(1):12
Melatonin regulates autophagy in granulosa cells from patients with premature ovarian insufficiency via activating Foxo3a.
Li P, Dou Q, Zhang D, Xiang Y, Tan L
Aging 2024 Jan 10;16(1):844-856
Aging 2024 Jan 10;16(1):844-856
Tripartite motif-containing protein 26 promotes colorectal cancer growth by inactivating p53.
Lu H, Tan Z, Ko H, Naji P, Zhu R, Wang J, Huang S, Zhang YW, Zeng S
Research square 2024 Jan 10;
Research square 2024 Jan 10;
Epigenetic inhibition of CTCF by HN1 promotes dedifferentiation and stemness of anaplastic thyroid cancer.
Pan Z, Lu X, Xu T, Chen J, Bao L, Li Y, Gong Y, Che Y, Zou X, Tan Z, Huang P, Ge M
Cancer letters 2024 Jan 1;580:216496
Cancer letters 2024 Jan 1;580:216496
RNA-binding protein hnRNPU regulates multiple myeloma resistance to selinexor.
Wang X, Xu J, Li Q, Zhang Y, Lin Z, Zhai X, Wang F, Huang J, Gao Q, Wen J, Li L, Feng Y, Luo H, Li Q, Liu X, Li J, Zhao F, Zhang L, Niu T, Sun C, Zheng Y
Cancer letters 2024 Jan 1;580:216486
Cancer letters 2024 Jan 1;580:216486
Upregulated Tβ4 expression in inflammatory bowel disease impairs the intestinal mucus barrier by inhibiting autophagy in mice.
Hao M, Zhong K, Bai X, Wu S, Li L, He Y, Wang Z, Sun X, Wang Q, Guo Y, Sun Y, Wu L
Experimental cell research 2024 Jan 1;434(1):113871
Experimental cell research 2024 Jan 1;434(1):113871
Manipulating HGF signaling reshapes the cirrhotic liver niche and fills a therapeutic gap in regeneration mediated by transplanted stem cells.
Zhang H, Chen Q, Hu D, Lai J, Yan M, Wu Z, Yang Z, Zheng S, Liu W, Zhang L, Bai L
Experimental cell research 2024 Jan 1;434(1):113867
Experimental cell research 2024 Jan 1;434(1):113867
Identification of FOXP3(+) epithelial cells contributing to pancreatic proliferation and angiogenesis.
Gong R, Chen X, Sun X, Zhang Y, Wang J, Yu Q, Lei K, Ren H
American journal of physiology. Cell physiology 2024 Jan 1;326(1):C294-C303
American journal of physiology. Cell physiology 2024 Jan 1;326(1):C294-C303
Triclosan induces earlier puberty onset in female mice via interfering with L-type calcium channels and activating Pik3cd.
Gan H, Lan H, Hu Z, Zhu B, Sun L, Jiang Y, Wu L, Liu J, Ding Z, Ye X
Ecotoxicology and environmental safety 2024 Jan 1;269:115772
Ecotoxicology and environmental safety 2024 Jan 1;269:115772
The role of estrogen receptors (ERs)-Notch pathway in thyroid toxicity induced by Di-2-ethylhexyl phthalate (DEHP) exposure: Population data and in vitro studies.
Zhang X, Zhang Y, Feng X, Zhao H, Ye H, Fang X, Cui J, Qi W, Ye L
Ecotoxicology and environmental safety 2024 Jan 1;269:115727
Ecotoxicology and environmental safety 2024 Jan 1;269:115727
Intranasal oxytocin alleviates comorbid depressive symptoms in neuropathic pain via elevating hippocampal BDNF production in both female and male mice.
Liu R, Sun D, Xing X, Chen Q, Lu B, Meng B, Yuan H, Mo L, Sheng L, Zheng J, Wang Q, Chen J, Chen X
Neuropharmacology 2024 Jan 1;242:109769
Neuropharmacology 2024 Jan 1;242:109769
Synergistic anticancer effect by targeting CDK2 and EGFR-ERK signaling.
Wu J, Chen Y, Li R, Guan Y, Chen M, Yin H, Yang X, Jin M, Huang B, Ding X, Yang J, Wang Z, He Y, Wang Q, Luo J, Wang P, Mao Z, Huen MSY, Lou Z, Yuan J, Gong F
The Journal of cell biology 2024 Jan 1;223(1)
The Journal of cell biology 2024 Jan 1;223(1)
Oncostatin M/Oncostatin M Receptor Signal Induces Radiation-Induced Heart Fibrosis by Regulating SMAD4 in Fibroblast.
Xu P, Yi Y, Xiong L, Luo Y, Xie C, Luo D, Zeng Z, Liu A
International journal of radiation oncology, biology, physics 2024 Jan 1;118(1):203-217
International journal of radiation oncology, biology, physics 2024 Jan 1;118(1):203-217
Individualized treatment with voriconazole in the Chinese population: Inflammation level as a novel marker for dose optimization.
Hao X, Li Y, Zhang Y, Bian J, Zhao J, Zhao Y, Hu L, Luo X, Yang C, Feng Y, Huang L
British journal of clinical pharmacology 2024 Feb;90(2):440-451
British journal of clinical pharmacology 2024 Feb;90(2):440-451
Genome-wide meta-analysis, functional genomics and integrative analyses implicate new risk genes and therapeutic targets for anxiety disorders.
Li W, Chen R, Feng L, Dang X, Liu J, Chen T, Yang J, Su X, Lv L, Li T, Zhang Z, Luo XJ
Nature human behaviour 2024 Feb;8(2):361-379
Nature human behaviour 2024 Feb;8(2):361-379
Excessive SOX8 reprograms energy and iron metabolism to prime hepatocellular carcinoma for ferroptosis.
Yang X, Gu C, Cai J, Li F, He X, Luo L, Xiao W, Hu B, Hu J, Qian H, Ren S, Zhang L, Zhu X, Yang L, Yang J, Yang Z, Zheng Y, Huang X, Wang Z
Redox biology 2024 Feb;69:103002
Redox biology 2024 Feb;69:103002
Inhibition of the RBMS1/PRNP axis improves ferroptosis resistance-mediated oxaliplatin chemoresistance in colorectal cancer.
Xu Y, Hao J, Chen Q, Qin Y, Qin H, Ren S, Sun C, Zhu Y, Shao B, Zhang J, Wang H
Molecular carcinogenesis 2024 Feb;63(2):224-237
Molecular carcinogenesis 2024 Feb;63(2):224-237
Electroacupuncture Promotes Nerve Regeneration and Functional Recovery Through Regulating lncRNA GAS5 Targeting miR-21 After Sciatic Nerve Injury.
Tian MY, Yang YD, Qin WT, Liu BN, Mou FF, Zhu J, Guo HD, Shao SJ
Molecular neurobiology 2024 Feb;61(2):935-949
Molecular neurobiology 2024 Feb;61(2):935-949
Alisol A Exerts Neuroprotective Effects Against HFD-Induced Pathological Brain Aging via the SIRT3-NF-κB/MAPK Pathway.
Lu T, Ding L, Zheng X, Li Y, Wei W, Liu W, Tao J, Xue X
Molecular neurobiology 2024 Feb;61(2):753-771
Molecular neurobiology 2024 Feb;61(2):753-771
Asiaticoside Attenuates Blood-Spinal Cord Barrier Disruption by Inhibiting Endoplasmic Reticulum Stress in Pericytes After Spinal Cord Injury.
Hu Z, Wu T, Zhou Z, Zhang Y, Chen Q, Yao H, Ji M, Shen G, Dong C, Shi C, Huang Z, Jiang N, Han N, Tian X
Molecular neurobiology 2024 Feb;61(2):678-692
Molecular neurobiology 2024 Feb;61(2):678-692
Pyruvate kinase M2 regulates kidney fibrosis through pericyte glycolysis during the progression from acute kidney injury to chronic kidney disease.
Chen Y, Bai X, Chen J, Huang M, Hong Q, Ouyang Q, Sun X, Zhang Y, Liu J, Wang X, Wu L, Chen X
Cell proliferation 2024 Feb;57(2):e13548
Cell proliferation 2024 Feb;57(2):e13548
Oncogenic lncRNA FAM215A promotes the malignant cell phenotypes of acute myeloid leukemia (AML) cell lines.
Li L, Xin L, Yang X, Zou Z
Journal of molecular histology 2024 Feb;55(1):97-108
Journal of molecular histology 2024 Feb;55(1):97-108
Interleukin-17 alleviates erastin-induced alveolar bone loss by suppressing ferroptosis via interaction between NRF2 and p-STAT3.
Bao J, Wang Z, Yang Y, Yu X, Yuan W, Sun W, Chen L
Journal of clinical periodontology 2024 Feb;51(2):233-250
Journal of clinical periodontology 2024 Feb;51(2):233-250
Involvement of PI3K/AKT Pathway in the Rapid Antidepressant Effects of Crocetin in Mice with Depression-Like Phenotypes.
Lin S, Chen Z, Wu Z, Fei F, Xu Z, Tong Y, Sun W, Wang P
Neurochemical research 2024 Feb;49(2):477-491
Neurochemical research 2024 Feb;49(2):477-491
Spindle and kinetochore-related complex subunit 3 has a protumour function in osteosarcoma by activating the Notch pathway.
Liang G, Duan C, He J, Shi L
Toxicology and applied pharmacology 2024 Feb;483:116826
Toxicology and applied pharmacology 2024 Feb;483:116826
Overexpression of PPM1B inhibited chemoresistance to temozolomide and proliferation in glioma cells.
Yu Y, Liu Q, Ran Q, Cao F
Cell biology international 2024 Feb;48(2):143-153
Cell biology international 2024 Feb;48(2):143-153
Deep learning enables the discovery of a novel cuproptosis-inducing molecule for the inhibition of hepatocellular carcinoma.
Yang F, Jia L, Zhou HC, Huang JN, Hou MY, Liu FT, Prabhu N, Li ZJ, Yang CB, Zou C, Nordlund P, Wang JG, Dai LY
Acta pharmacologica Sinica 2024 Feb;45(2):391-404
Acta pharmacologica Sinica 2024 Feb;45(2):391-404
Caffeic acid alleviates cerebral ischemic injury in rats by resisting ferroptosis via Nrf2 signaling pathway.
Li XN, Shang NY, Kang YY, Sheng N, Lan JQ, Tang JS, Wu L, Zhang JL, Peng Y
Acta pharmacologica Sinica 2024 Feb;45(2):248-267
Acta pharmacologica Sinica 2024 Feb;45(2):248-267
Efficacy of Ganshuang granules on non-alcoholic fatty liver and underlying mechanism: a network pharmacology and experimental verification.
Guoguo Z, Bingjie S, Tianyan Z, Shaoxiu JI, Jingwei LI, Yanni D, Feng L, Dong W
Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan 2024 Feb;44(1):122-130
Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan 2024 Feb;44(1):122-130
A comprehensive analysis of the expression, immune infiltration, prognosis and partial experimental validation of CHST family genes in gastric cancer.
Zhan J, Zhou L, Zhang H, Zhou J, He Y, Hu T, Le Y, Lin Y, Wang J, Yu H, Liu Y, Xiang X
Translational oncology 2024 Feb;40:101843
Translational oncology 2024 Feb;40:101843
METTL3 promotes microglial inflammation via MEF2C in spinal cord injury.
Wang D, Qian W, Wu D, Wu Y, Lu K, Zou G
Cell and tissue research 2024 Feb;395(2):189-197
Cell and tissue research 2024 Feb;395(2):189-197
Mutual antagonism of mouse-adaptation mutations in HA and PA proteins on H9N2 virus replication.
Ma L, Zheng H, Ke X, Gui R, Yao Z, Xiong J, Chen Q
Virologica Sinica 2024 Feb;39(1):56-70
Virologica Sinica 2024 Feb;39(1):56-70
Drug repurposing screen identifies vidofludimus calcium and pyrazofurin as novel chemical entities for the development of hepatitis E interventions.
Guo H, Liu D, Liu K, Hou Y, Li C, Li Q, Ding X, Verstegen MMA, Zhang J, Wang L, Ding Y, Tang R, Pan X, Zheng K, van der Laan LJW, Pan Q, Wang W
Virologica Sinica 2024 Feb;39(1):123-133
Virologica Sinica 2024 Feb;39(1):123-133
Icariside II prevents kidney fibrosis development in chronic kidney disease by promoting fatty acid oxidation.
Wang M, Wang J, Wang L, Feng X, Qian Y, Ye C, Wang C
Phytotherapy research : PTR 2024 Feb;38(2):839-855
Phytotherapy research : PTR 2024 Feb;38(2):839-855
Epigallocatechin-3-gallate promotes wound healing response in diabetic mice by activating keratinocytes and promoting re-epithelialization.
Ning Y, Yuan Z, Wang Q, He J, Zhu W, Ren DN, Wo D
Phytotherapy research : PTR 2024 Feb;38(2):1013-1027
Phytotherapy research : PTR 2024 Feb;38(2):1013-1027
Spinal interleukin-24 contributes to neuropathic pain after peripheral nerve injury through interleukin-20 receptor2 in mice.
Cai Y, He C, Dai Y, Zhang D, Lv G, Lu H, Chen G
Experimental neurology 2024 Feb;372:114643
Experimental neurology 2024 Feb;372:114643
Ultrasound-mediated HGF Gene Microbubbles Mitigate Hyperkinetic Pulmonary Arterial Hypertension in Rabbits.
Liu C, Lv X, Kong X, Meng L, Wei K, Wei R, Tang M, Li J, Cao G
Heart, lung & circulation 2024 Feb;33(2):251-259
Heart, lung & circulation 2024 Feb;33(2):251-259
Sesquiterpene from Artemisia argyi seed extracts: A new anti-acute peritonitis agent that suppresses the MAPK pathway and promotes autophagy.
Li Y, Wang Y, Li T, Li Z, Guo T, Xue G, Duan Y, Yao Y
Inflammopharmacology 2024 Feb;32(1):447-460
Inflammopharmacology 2024 Feb;32(1):447-460
Aurora kinase A-mediated phosphorylation triggers structural alteration of Rab1A to enhance ER complexity during mitosis.
Zhang W, Zhang Z, Xiang Y, Gu DD, Chen J, Chen Y, Zhai S, Liu Y, Jiang T, Liu C, He B, Yan M, Wang Z, Xu J, Cao YL, Deng B, Zeng D, Lei J, Zhuo J, Lei X, Long Z, Jin B, Chen T, Li D, Shen Y, Hu J, Gao S, Liu Q
Nature structural & molecular biology 2024 Feb;31(2):219-231
Nature structural & molecular biology 2024 Feb;31(2):219-231
ABLIM1, a novel ubiquitin E3 ligase, promotes growth and metastasis of colorectal cancer through targeting IĸBα ubiquitination and activating NF-ĸB signaling.
He Y, Shi Q, Ling Y, Guo H, Fei Y, Wu R, Tang C, Zhang X, Yao L
Cell death and differentiation 2024 Feb;31(2):203-216
Cell death and differentiation 2024 Feb;31(2):203-216
LncNFYB promotes the proliferation of rheumatoid arthritis fibroblast-like synoviocytes via LncNFYB/ANXA2/ERK1/2 axis.
Xiao S, Ouyang Q, Feng Y, Lu X, Han Y, Ren H, Huang Q, Zhao J, Xiao C, Yang M
The Journal of biological chemistry 2024 Feb;300(2):105591
The Journal of biological chemistry 2024 Feb;300(2):105591
Targeting blood brain barrier-Remote ischemic conditioning alleviates cognitive impairment in female APP/PS1 rats.
Ma Y, Sun W, Bai J, Gao F, Ma H, Liu H, Hu J, Xu C, Zhang X, Liu Z, Yuan T, Sun C, Huang Y, Wang R
CNS neuroscience & therapeutics 2024 Feb;30(2):e14613
CNS neuroscience & therapeutics 2024 Feb;30(2):e14613
Polygalacic acid attenuates cognitive impairment by regulating inflammation through PPARγ/NF-κB signaling pathway.
Zhao T, Jia J
CNS neuroscience & therapeutics 2024 Feb;30(2):e14581
CNS neuroscience & therapeutics 2024 Feb;30(2):e14581
PGAM5 knockout causes depressive-like behaviors in mice via ATP deficiency in the prefrontal cortex.
Cui W, Chen C, Gong L, Wen J, Yang S, Zheng M, Gao B, You J, Lin X, Hao Y, Chen Z, Wu Z, Gao L, Tang J, Yuan Z, Sun X, Jing L, Wen G
CNS neuroscience & therapeutics 2024 Feb;30(2):e14377
CNS neuroscience & therapeutics 2024 Feb;30(2):e14377
The G protein-coupled estrogen receptor of the trigeminal ganglion regulates acute and chronic itch in mice.
Li J, Gao P, Zhang S, Lin X, Chen J, Zhang S, Jiao Y, Yu W, Xia X, Yang L
CNS neuroscience & therapeutics 2024 Feb;30(2):e14367
CNS neuroscience & therapeutics 2024 Feb;30(2):e14367
Enriched environment ameliorates fear memory impairments induced by sleep deprivation via inhibiting PIEZO1/calpain/autophagy signaling pathway in the basal forebrain.
Zhang ZQ, Lu Y, Zhang H, Dong SH, Wu YT, Wang SN, Huang AH, Jiang QS, Yin SM
CNS neuroscience & therapeutics 2024 Feb;30(2):e14365
CNS neuroscience & therapeutics 2024 Feb;30(2):e14365
Huangqin Decoction Delays Progress of Colitis-Associated Carcinogenesis by Regulating Nrf2/HO-1 Antioxidant Signal Pathway in Mice.
Gu LM, Li HZ, Gao L, Li H, Wei LF, Pan CY, Wu KX, Tian YZ
Chinese journal of integrative medicine 2024 Feb;30(2):135-142
Chinese journal of integrative medicine 2024 Feb;30(2):135-142
Promoting effect and immunologic role of secretogranin II on bladder cancer progression via regulating MAPK and NF-κB pathways.
Zhou J, Dong C, Tan J, Wang G, Li Z, Li S, He Z
Apoptosis : an international journal on programmed cell death 2024 Feb;29(1-2):121-141
Apoptosis : an international journal on programmed cell death 2024 Feb;29(1-2):121-141
Cholesterol depletion inhibits rabies virus infection by restricting viral adsorption and fusion.
Hou Q, Wang C, Xiong J, Wang H, Wang Z, Zhao J, Wu Q, Fu ZF, Zhao L, Zhou M
Veterinary microbiology 2024 Feb;289:109952
Veterinary microbiology 2024 Feb;289:109952
Porcine delta coronavirus inhibits NHE3 activity of porcine intestinal epithelial cells through miR-361-3p/NHE3 regulatory axis.
Huang Z, Cao M, Fan H, Sun Y, Lan T, Ma J, Li Q
Veterinary microbiology 2024 Feb;289:109916
Veterinary microbiology 2024 Feb;289:109916
Lead exposure induced transgenerational developmental neurotoxicity by altering genome methylation in Drosophila melanogaster.
Wu C, Wang J, Luo X, Wang B, Zhang X, Song Y, Zhang K, Zhang X, Sun M
Ecotoxicology and environmental safety 2024 Feb;271:115991
Ecotoxicology and environmental safety 2024 Feb;271:115991
Proteomic analysis reveals that cigarette smoke exposure diminishes ovarian reserve in mice by disrupting the CREB1-mediated ovarian granulosa cell proliferation-apoptosis balance.
Xu M, Li F, Xu X, Hu N, Miao J, Zhao Y, Ji S, Wang Y, Wang L
Ecotoxicology and environmental safety 2024 Feb;271:115989
Ecotoxicology and environmental safety 2024 Feb;271:115989
Safranal acts as a neurorestorative agent in rats with cerebral ischemic stroke via upregulating SIRT1.
He F, Chen C, Wang Y, Wang S, Lyu S, Jiao J, Huang G, Yang J
Experimental and therapeutic medicine 2024 Feb;27(2):71
Experimental and therapeutic medicine 2024 Feb;27(2):71
Downregulation of NEBL promotes migration and invasion of clear cell renal cell carcinoma by inducing epithelial-mesenchymal transition.
Zhao R, Liang Z, Chu J, Zheng Q, Zhao J, Tang S, Chen Q, Huang Y, Zhou X, Pan X
Pathology, research and practice 2024 Feb;254:155068
Pathology, research and practice 2024 Feb;254:155068
Aurora kinase B disruption suppresses pathological retinal angiogenesis by affecting cell cycle progression.
Zhu W, Gui X, Zhou Y, Gao X, Zhang R, Li Q, Zhang H, Zhao J, Cui X, Gao G, Tang H, Huan C, Pan D, Song H, Zhou Z, Shen W
Experimental eye research 2024 Feb;239:109753
Experimental eye research 2024 Feb;239:109753
Natural isoflavone glabridin targets PI3Kγ as an adjuvant to increase the sensitivity of MDA-MB-231 to tamoxifen and DU145 to paclitaxel.
Lin H, Ai D, Liu Q, Wang X, Chen Q, Hong Z, Tao Y, Gao J, Wang L
The Journal of steroid biochemistry and molecular biology 2024 Feb;236:106426
The Journal of steroid biochemistry and molecular biology 2024 Feb;236:106426
Transcription factor c-Maf drives macrophages to promote hypertrophic scar formation.
Yang L, Song Y, Wang T, Cui Z, Wu J, Shi Y, Yu Z, Song B
Journal of cosmetic dermatology 2024 Feb;23(2):639-647
Journal of cosmetic dermatology 2024 Feb;23(2):639-647
The long noncoding RNA HNF1A-AS1 with dual functions in the regulation of cytochrome P450 3A4.
Wang Y, Wang P, Wang Q, Chen S, Wang X, Zhong X, Hu W, Thorne RF, Han S, Wu M, Zhang L
Biochemical pharmacology 2024 Feb;220:116016
Biochemical pharmacology 2024 Feb;220:116016
Upregulation of TRIM16 mitigates doxorubicin-induced cardiotoxicity by modulating TAK1 and YAP/Nrf2 pathways in mice.
Guo X, Liu M, Han B, Zheng Y, Zhang K, Bao G, Gao C, Shi H, Sun Q, Zhao Z
Biochemical pharmacology 2024 Feb;220:116009
Biochemical pharmacology 2024 Feb;220:116009
4-octyl itaconate protects against oxidative stress-induced liver injury by activating the Nrf2/Sirt3 pathway through AKT and ERK1/2 phosphorylation.
Hu Z, Xu D, Meng H, Liu W, Zheng Q, Wang J
Biochemical pharmacology 2024 Feb;220:115992
Biochemical pharmacology 2024 Feb;220:115992
Deferoxamine reduces endothelial ferroptosis and protects cerebrovascular function after experimental traumatic brain injury.
Liang Y, Wang Y, Sun C, Xiang Y, Deng Y
Brain research bulletin 2024 Feb;207:110878
Brain research bulletin 2024 Feb;207:110878
Improvement of astrocytic gap junction involves the anti-depressive effect of celecoxib through inhibition of NF-κB.
Zheng XX, Zhang CF, Li LQ, Ye JR, Ren SY, Zhang Z, He X, Chu SF, Chen NH
Brain research bulletin 2024 Feb;207:110871
Brain research bulletin 2024 Feb;207:110871
Targeting CD38/ ADP-ribosyl cyclase as a novel therapeutic strategy for identification of three potent agonists for leukopenia treatment.
Liu Y, Zhang L, Wang L, Tang X, Wan S, Huang Q, Ran M, Shen H, Yang Y, Chiampanichayakul S, Tima S, Anuchapreeda S, Wu J
Pharmacological research 2024 Feb;200:107068
Pharmacological research 2024 Feb;200:107068
NSD2 modulates Drp1-mediated mitochondrial fission in chronic renal allograft interstitial fibrosis by methylating STAT1.
Zhang J, Xie W, Ni B, Li Z, Feng D, Zhang Y, Han Q, Zhou H, Gu M, Tan R
Pharmacological research 2024 Feb;200:107051
Pharmacological research 2024 Feb;200:107051
G-Quadruplex/Hemin DNAzyme-Functionalized Silver Nanoclusters with Synergistic Antibacterial and Wound Healing Capabilities for Infected Wound Management.
Zhu J, Wen T, Qu S, Li Q, Liu B, Zhou W
Small (Weinheim an der Bergstrasse, Germany) 2024 Feb;20(8):e2307220
Small (Weinheim an der Bergstrasse, Germany) 2024 Feb;20(8):e2307220
Downregulation of CPSF6 leads to global mRNA 3' UTR shortening and enhanced antiviral immune responses.
Ge Y, Huang J, Chen R, Fu Y, Ling T, Ou X, Rong X, Cheng Y, Lin Y, Zhou F, Lu C, Yuan S, Xu A
PLoS pathogens 2024 Feb;20(2):e1012061
PLoS pathogens 2024 Feb;20(2):e1012061
TRIM72 restricts lyssavirus infection by inducing K48-linked ubiquitination and proteasome degradation of the matrix protein.
Sui B, Zheng J, Fu Z, Zhao L, Zhou M
PLoS pathogens 2024 Feb;20(2):e1011718
PLoS pathogens 2024 Feb;20(2):e1011718
ER stress elicits non-canonical CASP8 (caspase 8) activation on autophagosomal membranes to induce apoptosis.
Hattori T, Fundora KA, Hamamoto K, Opozda DM, Liang X, Liu X, Zhang J, Uzun Y, Takahashi Y, Wang HG
Autophagy 2024 Feb;20(2):349-364
Autophagy 2024 Feb;20(2):349-364
Molecular mechanism of honeysuckle + forsythia in treatment of acute lung injury based on network pharmacology.
Wen X, Cheng M, Song Z, Hu J, Liang X, Lang W, Yang M, Zhou R, Hao Y
Biomedical reports 2024 Feb;20(2):32
Biomedical reports 2024 Feb;20(2):32
NLRP3 activation in macrophages promotes acute intestinal injury in neonatal necrotizing enterocolitis.
Shi B, Lyu CJ, Le ZK, Ji HS, Xiao Y, Zhang YY, Huang SJ, Yu LJ, Shu Q, Tou JF, Lai DM
World journal of pediatrics : WJP 2024 Feb;20(2):153-164
World journal of pediatrics : WJP 2024 Feb;20(2):153-164
ARHGAP18 is Upregulated by Transcription Factor GATA1 Promotes the Proliferation and Invasion in Hepatocellular Carcinoma.
Chen P, Liu X, Liu Y, Bao X, Wu Q
Applied biochemistry and biotechnology 2024 Feb;196(2):679-689
Applied biochemistry and biotechnology 2024 Feb;196(2):679-689
The novel antibody fusion protein rhNRG1-HER3i promotes heart regeneration by enhancing NRG1-ERBB4 signaling pathway.
Wang X, Wu H, Tang L, Fu W, He Y, Zeng C, Wang WE
Journal of molecular and cellular cardiology 2024 Feb;187:26-37
Journal of molecular and cellular cardiology 2024 Feb;187:26-37
mTORC1 regulates the metabolic switch of postnatal cardiomyocytes during regeneration.
Paltzer WG, Aballo TJ, Bae J, Flynn CGK, Wanless KN, Hubert KA, Nuttall DJ, Perry C, Nahlawi R, Ge Y, Mahmoud AI
Journal of molecular and cellular cardiology 2024 Feb;187:15-25
Journal of molecular and cellular cardiology 2024 Feb;187:15-25
Isoflavones isolated from chickpea sprouts alleviate ovariectomy-induced osteoporosis in rats by dual regulation of bone remodeling.
Huang J, Zheng J, Dadihanc T, Gao Y, Zhang Y, Li Z, Wang X, Yu L, Mijiti W, Xie Z, Ma H
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Feb;171:116214
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Feb;171:116214
Targeting ROCK1 in diabetic kidney disease: Unraveling mesangial fibrosis mechanisms and introducing myricetin as a novel antagonist.
Yuan N, Diao J, Dong J, Yan Y, Chen Y, Yan S, Liu C, He Z, He J, Zhang C, Wang H, Wang M, He F, Xiao W
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Feb;171:116208
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Feb;171:116208
GIMAP7 inhibits epithelial-mesenchymal transition and glycolysis in lung adenocarcinoma cells via regulating the Smo/AMPK signaling pathway.
Cui L, Shen Y, Duan S, Ding Q, Wang Y, Yang W, Chen Y
Thoracic cancer 2024 Feb;15(4):286-298
Thoracic cancer 2024 Feb;15(4):286-298
A novel biomarker of fibrofatty replacement in dystrophinopathies identified by integrating transcriptome, magnetic resonance imaging, and pathology data.
Xie Z, Liu C, Sun C, Lu Y, Wu S, Liu Y, Wang Q, Wan Y, Wang Y, Yu M, Meng L, Deng J, Zhang W, Wang Z, Yang C, Yuan Y, Xie Z
Journal of cachexia, sarcopenia and muscle 2024 Feb;15(1):98-111
Journal of cachexia, sarcopenia and muscle 2024 Feb;15(1):98-111
Near-infrared light controlled protein degradation by photo-caged lenalidomide and pomalidomide.
Zhu Y, Yan X, Shi Y, Liu B, Huang W, Chu L
Bioorganic chemistry 2024 Feb;143:107050
Bioorganic chemistry 2024 Feb;143:107050
Sulfotransferase SULT2B1 facilitates colon cancer metastasis by promoting SCD1-mediated lipid metabolism.
Che G, Wang W, Wang J, He C, Yin J, Chen Z, He C, Wang X, Yang Y, Liu J
Clinical and translational medicine 2024 Feb;14(2):e1587
Clinical and translational medicine 2024 Feb;14(2):e1587
The involvement of RNA N6-methyladenosine and histone methylation modification in decidualization and endometriosis-associated infertility.
Lin X, Dai Y, Gu W, Zhang Y, Zhuo F, Zhao F, Jin X, Li C, Huang D, Tong X, Zhang S
Clinical and translational medicine 2024 Feb;14(2):e1564
Clinical and translational medicine 2024 Feb;14(2):e1564
Hyaluronic Acid-Based Reactive Oxygen Species-Responsive Multifunctional Injectable Hydrogel Platform Accelerating Diabetic Wound Healing.
Shi C, Zhang Y, Wu G, Zhu Z, Zheng H, Sun X, Heng Y, Pan S, Xiu H, Zhang J, Yin Z, Yu Z, Liang B
Advanced healthcare materials 2024 Feb;13(4):e2302626
Advanced healthcare materials 2024 Feb;13(4):e2302626
Tumor suppressive function of IGF2BP1 in gastric cancer through decreasing MYC.
Ding N, Cao G, Wang Z, Xu S, Chen W
Cancer science 2024 Feb;115(2):427-438
Cancer science 2024 Feb;115(2):427-438
Deubiquitinating enzyme PSMD7 promotes bladder cancer development: Involvement of RAB1A stabilization.
Wang J, Wang T, Feng YK, Liu Y, Fu B, Liu XT, Wu QZ
Cellular signalling 2024 Feb;114:110996
Cellular signalling 2024 Feb;114:110996
MPDZ is associated with immune infiltration and regulates migration and invasion by switching YAP1 phosphorylation in colorectal cancer.
Chen Z, Ba Y, Zhao N, Dang Q, Xu H, Weng S, Zhang Y, Liu S, Zuo A, Han X, Liu Z
Cellular signalling 2024 Feb;114:110967
Cellular signalling 2024 Feb;114:110967
BHLHE40 Inhibits Ferroptosis in Pancreatic Cancer Cells via Upregulating SREBF1.
Cao Y, Wang X, Liu Y, Liu P, Qin J, Zhu Y, Zhai S, Jiang Y, Liu Y, Han L, Luo J, Zhang R, Shi M, Wang L, Tang X, Xue M, Liu J, Wang W, Wen C, Deng X, Peng C, Chen H, Cheng D, Jiang L, Shen B
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Feb;11(7):e2306298
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Feb;11(7):e2306298
Phosphorylation of RGS16 at Tyr168 promote HBeAg-mediated macrophage activation by ERK pathway to accelerate liver injury.
Tian M, Wu N, Xie X, Liu T, You Y, Ma S, Bian H, Cao H, Wang L, Liu C, Qi J
Journal of molecular medicine (Berlin, Germany) 2024 Feb;102(2):257-272
Journal of molecular medicine (Berlin, Germany) 2024 Feb;102(2):257-272
DSPE-PEG(2000)-methotrexate nanoparticles encapsulating phenobarbital sodium kill cancer cells by inducing pyroptosis.
Yin F, Xu X, Qi J, Guo M, Wang Y, Wang Y, Ye R, Lin Q, Yang D, Zhu X, Wang J
Journal of molecular medicine (Berlin, Germany) 2024 Feb;102(2):213-229
Journal of molecular medicine (Berlin, Germany) 2024 Feb;102(2):213-229
Functional analysis of Cdc20 reveals a critical role of CRY box in mitotic checkpoint signaling.
Zhang Y, Young R, Garvanska DH, Song C, Zhai Y, Wang Y, Jiang H, Fang J, Nilsson J, Alfieri C, Zhang G
Communications biology 2024 Feb 9;7(1):164
Communications biology 2024 Feb 9;7(1):164
MTHFD1 regulates the NADPH redox homeostasis in MYCN-amplified neuroblastoma.
Guan J, Li M, Wang Y, Zhang Y, Que Y, Lu S, Wang J, Zhu J, Huang J, Zhen Z, Sun F, Song M, Zhang Y
Cell death & disease 2024 Feb 9;15(2):124
Cell death & disease 2024 Feb 9;15(2):124
NOTCH1 as a Negative Regulator of Avian Adipocyte Differentiation: Implications for Fat Deposition.
Wang Z, Su Y, Zhao M, Ma Z, Li J, Hou Z, Li H
Animals : an open access journal from MDPI 2024 Feb 9;14(4)
Animals : an open access journal from MDPI 2024 Feb 9;14(4)
An oncolytic virus-T cell chimera for cancer immunotherapy.
Chen Y, Chen X, Bao W, Liu G, Wei W, Ping Y
Nature biotechnology 2024 Feb 9;
Nature biotechnology 2024 Feb 9;
Saracatinib inhibits necroptosis and ameliorates psoriatic inflammation by targeting MLKL.
Li J, Liu X, Liu Y, Huang F, Liang J, Lin Y, Hu F, Feng J, Han Z, Chen Y, Chen X, Lin Q, Wu L, Li L
Cell death & disease 2024 Feb 8;15(2):122
Cell death & disease 2024 Feb 8;15(2):122
The Schwann cell-specific G-protein Gαo (Gnao1) is a cell-intrinsic controller contributing to the regulation of myelination in peripheral nerve system.
Xu J, Peng Q, Cai J, Shangguan J, Su W, Chen G, Sun H, Zhu C, Gu Y
Acta neuropathologica communications 2024 Feb 8;12(1):24
Acta neuropathologica communications 2024 Feb 8;12(1):24
METTL14-mediated m6A epitranscriptomic modification contributes to chemotherapy-induced neuropathic pain by stabilizing GluN2A expression via IGF2BP2.
Lu W, Yang X, Zhong W, Chen G, Guo X, Ye Q, Xu Y, Qi Z, Ye Y, Zhang J, Wang Y, Wang X, Wang S, Zhao Q, Zeng W, Huang J, Ma H, Xie J
The Journal of clinical investigation 2024 Feb 6;134(6)
The Journal of clinical investigation 2024 Feb 6;134(6)
Inhibition of Cpeb3 ribozyme elevates CPEB3 protein expression and polyadenylation of its target mRNAs and enhances object location memory.
Chen CC, Han J, Chinn CA, Rounds JS, Li X, Nikan M, Myszka M, Tong L, Passalacqua LFM, Bredy T, Wood MA, Luptak A
eLife 2024 Feb 6;13
eLife 2024 Feb 6;13
Sulbactam protects neurons against double neurotoxicity of amyloid beta and glutamate load by upregulating glial glutamate transporter 1.
Li L, Li W, Jiang W, Xu R
Cell death discovery 2024 Feb 6;10(1):64
Cell death discovery 2024 Feb 6;10(1):64
Luteolin blocks the ROS/PI3K/AKT pathway to inhibit mesothelial-mesenchymal transition and reduce abdominal adhesions.
Ren Y, Li G, Li E, Deng K, Lian J, Gao Q, Wang H, Wang X, Wang Z, Shen T, Jiang Z, Li X, Qiu G
European journal of pharmacology 2024 Feb 5;964:176272
European journal of pharmacology 2024 Feb 5;964:176272
Tetrandrine downregulates TRPV2 expression to ameliorate myocardial ischemia/reperfusion injury in rats via regulation of cardiomyocyte apoptosis, calcium homeostasis and mitochondrial function.
Jiang L, Zhou X, Zhao X, Wang Z, Huang A, Huang Y, Sun H, Guan F, Jiang W
European journal of pharmacology 2024 Feb 5;964:176246
European journal of pharmacology 2024 Feb 5;964:176246
Inhibiting LCN2 can suppress the development of NSCLC by promoting ferroptosis.
Pan Z, Li B, Lu P, Rong G, Wang X
Gene 2024 Feb 5;894:148026
Gene 2024 Feb 5;894:148026
Dynamic palmitoylation of STX11 controls injury-induced fatty acid uptake to promote muscle regeneration.
Wang J, Li DL, Zheng LF, Ren S, Huang ZQ, Tao Y, Liu Z, Shang Y, Pang D, Guo H, Zeng T, Wang HR, Huang H, Du X, Ye H, Zhou HM, Li P, Zhao TJ
Developmental cell 2024 Feb 5;59(3):384-399.e5
Developmental cell 2024 Feb 5;59(3):384-399.e5
Macrophages Promote Subtype Conversion and Endocrine Resistance in Breast Cancer.
Zhang X, Yang F, Huang Z, Liu X, Xia G, Huang J, Yang Y, Li J, Huang J, Liu Y, Zhou T, Qi W, Gao G, Yang X
Cancers 2024 Feb 5;16(3)
Cancers 2024 Feb 5;16(3)
HAND factors regulate cardiac lineage commitment and differentiation from human pluripotent stem cells.
Guo H, Hang C, Lin B, Lin Z, Xiong H, Zhang M, Lu R, Liu J, Shi D, Xie D, Liu Y, Liang D, Yang J, Chen YH
Stem cell research & therapy 2024 Feb 5;15(1):31
Stem cell research & therapy 2024 Feb 5;15(1):31
Defining the mechanisms and properties of post-transcriptional regulatory disordered regions by high-throughput functional profiling.
Lobel JH, Ingolia NT
bioRxiv : the preprint server for biology 2024 Feb 5;
bioRxiv : the preprint server for biology 2024 Feb 5;
Cabergoline as a Novel Strategy for Post-Pregnancy Breast Cancer Prevention in Mice and Human.
García-Sancha N, Corchado-Cobos R, Blanco-Gómez A, Cunillera Puértolas O, Marzo-Castillejo M, Castillo-Lluva S, Alonso-López D, De Las Rivas J, Pozo J, Orfao A, Valero-Juan L, Patino-Alonso C, Perera D, Venkitaraman AR, Mao JH, Chang H, Mendiburu-Eliçabe M, González-García P, Caleiras E, Peset I, Cenador MBG, García-Criado FJ, Pérez-Losada J
Research square 2024 Feb 5;
Research square 2024 Feb 5;
Altered nuclear envelope homeostasis is a key pathogenic event in C9ORF72-linked ALS/FTD.
Sirtori R, Gregoire M, Collins A, Santangelo S, Chatragadda B, Cullen R, Ratti A, Fallini C
bioRxiv : the preprint server for biology 2024 Feb 4;
bioRxiv : the preprint server for biology 2024 Feb 4;
Hippocampal estrogens rescued the decline of synaptic plasticity after surgery and anesthesia by inhibiting microglia overactivation.
Tan XX, Dai HY, Yao J, Wang JJ, Dai YC, Zhang TH, Qiu LL, Sun J
Behavioural brain research 2024 Feb 29;459:114794
Behavioural brain research 2024 Feb 29;459:114794
CircMTA2 Drives Gastric Cancer Progression through Suppressing MTA2 Degradation via Interacting with UCHL3.
Xie G, Lei B, Yin Z, Xu F, Liu X
International journal of molecular sciences 2024 Feb 29;25(5)
International journal of molecular sciences 2024 Feb 29;25(5)
Improvement of idiopathic pulmonary fibrosis through a combination of Astragalus radix and Angelica sinensis radix via mammalian target of rapamycin signaling pathway-induced autophagy in rat.
Sun C, Liu H, Chi B, Han J, Koga Y, Afshar K, Liu X
Journal of thoracic disease 2024 Feb 29;16(2):1397-1411
Journal of thoracic disease 2024 Feb 29;16(2):1397-1411
ENO2 promotes anoikis resistance in anaplastic thyroid cancer by maintaining redox homeostasis.
Zhang Y, Ji X, Wang Y
Gland surgery 2024 Feb 29;13(2):209-224
Gland surgery 2024 Feb 29;13(2):209-224
SMG9 is a novel prognostic-related biomarker in glioma correlating with ferroptosis and immune infiltrates.
Dai Y, Zhang H, Feng S, Guo C, Tian W, Sun Y, Zhang Y
Heliyon 2024 Feb 29;10(4):e25716
Heliyon 2024 Feb 29;10(4):e25716
Ginseng-Sanqi-Chuanxiong (GSC) extracts attenuate d-galactose-induced vascular aging in mice via inhibition of endothelial progenitor cells senescence.
Liu Y, Liu Y, Wang X, Xiu C, Hu Y, Wang J, Lei Y, Yang J
Heliyon 2024 Feb 29;10(4):e25253
Heliyon 2024 Feb 29;10(4):e25253
Astragalus polysaccharide improves diabetic ulcers by promoting M2-polarization of macrophages to reduce excessive inflammation via the β-catenin/ NF-κB axis at the late phase of wound-healing.
Zhen Z, Wei S, Yunfei W, Jie X, Jienan X, Yiting S, Wen X, Shuyu G, Yue L, Xuanyu W, Yumei Z, Huafa Q
Heliyon 2024 Feb 29;10(4):e24644
Heliyon 2024 Feb 29;10(4):e24644
Driving effect of P16 methylation on telomerase reverse transcriptase-mediated immortalization and transformation of normal human fibroblasts.
Zhang X, Li P, Gan Y, Xiang S, Gu L, Zhou J, Zhou X, Wu P, Zhang B, Deng D
Chinese medical journal 2024 Feb 29;
Chinese medical journal 2024 Feb 29;
Mitochondria-Associated Protein FgNdk1 Regulates the Development, Pathogenicity, and SDHI Fungicide Sensitivity of Fusarium graminearum by Interacting with Succinate Dehydrogenase.
Wang C, Zhao F, Wu Z, Cai X, Zhou M, Hou Y
Journal of agricultural and food chemistry 2024 Feb 28;72(8):3913-3925
Journal of agricultural and food chemistry 2024 Feb 28;72(8):3913-3925
Molecular mechanism of human ISG20L2 for the ITS1 cleavage in the processing of 18S precursor ribosomal RNA.
Ma Y, Wang J, He X, Liu Y, Zhen S, An L, Yang Q, Niu F, Wang H, An B, Tai X, Yan Z, Wu C, Yang X, Liu X
Nucleic acids research 2024 Feb 28;52(4):1878-1895
Nucleic acids research 2024 Feb 28;52(4):1878-1895
Multi-omics analysis for ferroptosis-related genes as prognostic factors in cutaneous melanoma.
Wu M, Li K, Liao Y, Li L, Xiao X, Chen Y, Guo J, Hu F, Qu J, Wang Z, Feng H
Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences 2024 Feb 28;49(2):159-174
Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences 2024 Feb 28;49(2):159-174
Integrin α(4) Positive Subpopulation in Adipose Derived Stem Cells Effectively Reduces Infarct Size through Enhanced Engraftment into Myocardial Infarction.
Yuan Z, Tan J, Wang J
International journal of stem cells 2024 Feb 28;17(1):70-79
International journal of stem cells 2024 Feb 28;17(1):70-79
hnRNPA2B1 represses the disassembly of arsenite-induced stress granules and is essential for male fertility.
Wang X, Fan X, Zhang J, Wang F, Chen J, Wen Y, Wang L, Li T, Li H, Gu H, Zhang Y, Yuan S
Cell reports 2024 Feb 27;43(2):113769
Cell reports 2024 Feb 27;43(2):113769
Schwann cell promotes macrophage recruitment through IL-17B/IL-17RB pathway in injured peripheral nerves.
Huang Y, Wu L, Zhao Y, Guo J, Li R, Ma S, Ying Z
Cell reports 2024 Feb 27;43(2):113753
Cell reports 2024 Feb 27;43(2):113753
Pharmacological inhibition of neddylation impairs long interspersed element 1 retrotransposition.
Li Y, Shen S, Guo H, Li H, Zhang L, Zhang B, Yu XF, Wei W
Cell reports 2024 Feb 27;43(2):113749
Cell reports 2024 Feb 27;43(2):113749
KEAP1 promotes anti-tumor immunity by inhibiting PD-L1 expression in NSCLC.
Li J, Shi D, Li S, Shi X, Liu Y, Zhang Y, Wang G, Zhang C, Xia T, Piao HL, Liu HX
Cell death & disease 2024 Feb 27;15(2):175
Cell death & disease 2024 Feb 27;15(2):175
Machine learning reveals diverse cell death patterns in lung adenocarcinoma prognosis and therapy.
Wang S, Wang R, Hu D, Zhang C, Cao P, Huang J
NPJ precision oncology 2024 Feb 26;8(1):49
NPJ precision oncology 2024 Feb 26;8(1):49
Cross-Oxygen Gradients Transcriptomic Comparison Revealed the Central Role of MAPK and Hippo in Hypoxia-Mediated Mammary Proliferation Inhibition.
Hu Z, Lu Y, Cai J, Liu J, Wang D
Antioxidants (Basel, Switzerland) 2024 Feb 26;13(3)
Antioxidants (Basel, Switzerland) 2024 Feb 26;13(3)
SKP alleviates the ferroptosis in diabetic kidney disease through suppression of HIF-1α/HO-1 pathway based on network pharmacology analysis and experimental validation.
Yan Y, Yuan N, Chen Y, Ma Y, Chen A, Wang F, Yan S, He Z, He J, Zhang C, Wang H, Wang M, Diao J, Xiao W
Chinese medicine 2024 Feb 25;19(1):31
Chinese medicine 2024 Feb 25;19(1):31
ACADL-YAP axis activity in non-small cell lung cancer carcinogenicity.
Chen K, Hong C, Kong W, Li G, Liu Z, Zhu K, Lu C, Si P, Gao P, Ning G, Zhang R
Cancer cell international 2024 Feb 24;24(1):86
Cancer cell international 2024 Feb 24;24(1):86
JianPiYiShen formula prevents cisplatin-induced acute kidney injury in mice by improving necroptosis through MAPK pathway.
Li Z, He R, Liu J, Jin X, Jiang B, Lao Y, Yang S
BMC complementary medicine and therapies 2024 Feb 24;24(1):101
BMC complementary medicine and therapies 2024 Feb 24;24(1):101
Inhibition of ferroptosis reverses heart failure with preserved ejection fraction in mice.
Xiong Y, Liu X, Jiang L, Hao T, Wang Y, Li T
Journal of translational medicine 2024 Feb 24;22(1):199
Journal of translational medicine 2024 Feb 24;22(1):199
PRMT1-mediated PGK1 arginine methylation promotes colorectal cancer glycolysis and tumorigenesis.
Liu H, Chen X, Wang P, Chen M, Deng C, Qian X, Bai J, Li Z, Yu X
Cell death & disease 2024 Feb 24;15(2):170
Cell death & disease 2024 Feb 24;15(2):170
WSB1, as an E3 ligase, restrains myocardial ischemia-reperfusion injury by activating β-catenin signaling via promoting GSK3β ubiquitination.
Fang L, Tao Y, Che G, Yun Y, Ren M, Liu Y
Molecular medicine (Cambridge, Mass.) 2024 Feb 23;30(1):31
Molecular medicine (Cambridge, Mass.) 2024 Feb 23;30(1):31
A Marine Natural Product, Harzianopyridone, as an Anti-ZIKV Agent by Targeting RNA-Dependent RNA Polymerase.
Zhang K, Liang J, Zhang B, Huang L, Yu J, Xiao X, He Z, Tao H, Yuan J
Molecules (Basel, Switzerland) 2024 Feb 23;29(5)
Molecules (Basel, Switzerland) 2024 Feb 23;29(5)
Heme Oxygenase-1 Regulates Zearalenone-Induced Oxidative Stress and Apoptosis in Sheep Follicular Granulosa Cells.
Li Y, Gao Y, Yao D, Li Z, Wang J, Zhang X, Zhao X, Zhang Y
International journal of molecular sciences 2024 Feb 23;25(5)
International journal of molecular sciences 2024 Feb 23;25(5)
Tumoral C2 Regulates the Tumor Microenvironment by Increasing the Ratio of M1/M2 Macrophages and Tertiary Lymphoid Structures to Improve Prognosis in Melanoma.
Zhang G, Li S, Xiao W, Zhang C, Li T, Liao Z, Liu H, Xing R, Yao W, Yang J
Cancers 2024 Feb 23;16(5)
Cancers 2024 Feb 23;16(5)
A co-assembly platform engaging macrophage scavenger receptor A for lysosome-targeting protein degradation.
Wang Q, Yang X, Yuan R, Shen A, Wang P, Li H, Zhang J, Tian C, Jiang Z, Li W, Dong S
Nature communications 2024 Feb 23;15(1):1663
Nature communications 2024 Feb 23;15(1):1663
Interleukin-6 trans-signaling regulates monocyte chemoattractant protein-1 production in immune-mediated necrotizing myopathy.
Ma X, Gao HJ, Ge HZ, Zhang Q, Bu BT
Rheumatology (Oxford, England) 2024 Feb 23;
Rheumatology (Oxford, England) 2024 Feb 23;
MYC-dependent MiR-7-5p regulated apoptosis and autophagy in diffuse large B cell lymphoma by targeting AMBRA1.
Zhang C, Wang K, Tao J, Zheng C, Zhai L
Molecular and cellular biochemistry 2024 Feb 23;
Molecular and cellular biochemistry 2024 Feb 23;
Discovery of D25, a Potent and Selective MNK Inhibitor for Sepsis-Associated Acute Spleen Injury.
Li Q, Ke L, Yu D, Xu H, Zhang Z, Yu R, Jiang T, Guo YW, Su M, Jin X
Journal of medicinal chemistry 2024 Feb 22;67(4):3167-3189
Journal of medicinal chemistry 2024 Feb 22;67(4):3167-3189
Design, Synthesis, and Biological Evaluation of Dual Inhibitors of EGFR(L858R/T790M)/ACK1 to Overcome Osimertinib Resistance in Nonsmall Cell Lung Cancers.
Wang A, Shuai W, Wu C, Pei J, Yang P, Wang X, Li S, Liu J, Wang Y, Wang G, Ouyang L
Journal of medicinal chemistry 2024 Feb 22;67(4):2777-2801
Journal of medicinal chemistry 2024 Feb 22;67(4):2777-2801
Protective Effect of Vitamin K2 (MK-7) on Acute Lung Injury Induced by Lipopolysaccharide in Mice.
Yang W, Wang Y, Liu L, Liu L, Li S, Li Y
Current issues in molecular biology 2024 Feb 22;46(3):1700-1712
Current issues in molecular biology 2024 Feb 22;46(3):1700-1712
SPOCK2 modulates neuropathic pain by interacting with MT1-MMP to regulate astrocytic MMP-2 activation in rats with chronic constriction injury.
Wang C, Xu Y, Xu M, Sun C, Zhang X, Tao X, Song T
Journal of neuroinflammation 2024 Feb 22;21(1):57
Journal of neuroinflammation 2024 Feb 22;21(1):57
Advanced oxidation protein products attenuate the autophagy-lysosome pathway in ovarian granulosa cells by modulating the ROS-dependent mTOR-TFEB pathway.
Zhou XY, Lai YH, Zhang J, Li Y, Wu XM, Yang YZ, Zhang XF, Ma LZ, Zheng KM, Liu YD, Wang Z, Chen SL
Cell death & disease 2024 Feb 21;15(2):161
Cell death & disease 2024 Feb 21;15(2):161
Phospho-eIF4E stimulation regulates coronavirus entry by selective expression of cell membrane-residential factors.
Zhang X-Z, Wang J, Tian W-J, You J-L, Chi X-J, Wang X-J
Journal of virology 2024 Feb 20;98(2):e0194823
Journal of virology 2024 Feb 20;98(2):e0194823
Porcine reproductive and respiratory syndrome virus triggers Golgi apparatus fragmentation-mediated autophagy to facilitate viral self-replication.
Zhao S-s, Qian Q, Chen X-x, Lu Q, Xing G, Qiao S, Li R, Zhang G
Journal of virology 2024 Feb 20;98(2):e0184223
Journal of virology 2024 Feb 20;98(2):e0184223
N-terminal acetyltransferase 6 facilitates enterovirus 71 replication by regulating PI4KB expression and replication organelle biogenesis.
Yang H, Fan T, Xun M, Wu B, Guo S, Li X, Zhao X, Yao H, Wang H
Journal of virology 2024 Feb 20;98(2):e0174923
Journal of virology 2024 Feb 20;98(2):e0174923
Porcine deltacoronavirus nsp5 antagonizes type I interferon signaling by cleaving IFIT3.
Huang H, Lei X, Zhao C, Qin Y, Li Y, Zhang X, Li C, Lan T, Zhao B, Sun W, Lu H, Jin N
Journal of virology 2024 Feb 20;98(2):e0168223
Journal of virology 2024 Feb 20;98(2):e0168223
Polyethylenimine Triggers Dll4 Degradation to Regulate Angiogenesis In Vitro.
Cheng B, Li Y, Ji YB, Shi W, Li M, Zheng J, Ding L, Liu K, Fang L, Xu Y, Li H, Shao X
ACS omega 2024 Feb 20;9(7):7502-7510
ACS omega 2024 Feb 20;9(7):7502-7510
ALDH2 deficiency exacerbates MCD-diet induced MASLD by modulating bile acid metabolism.
Luo J, Lu Z, Zhong Z, Pi M, Xiong Y, Li L, Chen T, Chen Y, Wang CY, Liu Z, Ye Q
Free radical biology & medicine 2024 Feb 20;212:34-48
Free radical biology & medicine 2024 Feb 20;212:34-48
P21 resists ferroptosis in osteoarthritic chondrocytes by regulating GPX4 protein stability.
Zheng Z, Shang X, Sun K, Hou Y, Zhang X, Xu J, Liu H, Ruan Z, Hou L, Guo Z, Wang G, Xu F, Guo F
Free radical biology & medicine 2024 Feb 20;212:336-348
Free radical biology & medicine 2024 Feb 20;212:336-348
Kupffer cells abrogate homing and repopulation of allogeneic hepatic progenitors in injured liver site.
Abbas N, You K, Getachew A, Wu F, Hussain M, Huang X, Chen Y, Pan T, Li Y
Stem cell research & therapy 2024 Feb 20;15(1):48
Stem cell research & therapy 2024 Feb 20;15(1):48
Cepharanthine analogs mining and genomes of Stephania accelerate anti-coronavirus drug discovery.
Leng L, Xu Z, Hong B, Zhao B, Tian Y, Wang C, Yang L, Zou Z, Li L, Liu K, Peng W, Liu J, An Z, Wang Y, Duan B, Hu Z, Zheng C, Zhang S, Li X, Li M, Liu Z, Bi Z, He T, Liu B, Fan H, Song C, Tong Y, Chen S
Nature communications 2024 Feb 20;15(1):1537
Nature communications 2024 Feb 20;15(1):1537
Nucleoredoxin Redox Interactions Are Sensitized by Aging and Potentiated by Chronic Alcohol Consumption in the Mouse Liver.
Idelfonso-García OG, Alarcón-Sánchez BR, Guerrero-Escalera D, López-Hernández NA, Pérez-Hernández JL, Pacheco-Rivera R, Serrano-Luna J, Resendis-Antonio O, Muciño-Olmos EA, Aparicio-Bautista DI, Basurto-Islas G, Baltiérrez-Hoyos R, Vásquez-Garzón VR, Villa-Treviño S, Muriel P, Serrano H, Pérez-Carreón JI, Arellanes-Robledo J
Antioxidants (Basel, Switzerland) 2024 Feb 20;13(3)
Antioxidants (Basel, Switzerland) 2024 Feb 20;13(3)
IP3R2-mediated Ca(2+) release promotes LPS-induced cardiomyocyte pyroptosis via the activation of NLRP3/Caspase-1/GSDMD pathway.
Wu QR, Yang H, Zhang HD, Cai YJ, Zheng YX, Fang H, Wang ZF, Kuang SJ, Rao F, Huang HL, Deng CY, Chen CB
Cell death discovery 2024 Feb 20;10(1):91
Cell death discovery 2024 Feb 20;10(1):91
Single-Cell Transcriptomics Reveals the Heterogeneity of the Immune Landscape of IDH-Wild-Type High-Grade Gliomas.
Ran X, Zheng J, Chen L, Xia Z, Wang Y, Sun C, Guo C, Lin P, Liu F, Wang C, Zhou J, Sun C, Liu Q, Ma J, Qin Z, Zhu X, Xie Q
Cancer immunology research 2024 Feb 2;12(2):232-246
Cancer immunology research 2024 Feb 2;12(2):232-246
Mitochondrial-related genes PDK2, CHDH, and ALDH5A1 served as a diagnostic signature and correlated with immune cell infiltration in ulcerative colitis.
Yang Q, Zhang P, Han L, Shi P, Zhao Z, Cui D, Hong K
Aging 2024 Feb 19;16(4):3803-3822
Aging 2024 Feb 19;16(4):3803-3822
Tumorigenesis of basal muscle invasive bladder cancer was mediated by PTEN protein degradation resulting from SNHG1 upregulation.
Li T, Huang M, Sun N, Hua X, Chen R, Xie Q, Huang S, Du M, Zhao Y, Lin Q, Xu J, Han X, Zhao Y, Tian Z, Zhang Y, Chen W, Shen X, Huang C
Journal of experimental & clinical cancer research : CR 2024 Feb 17;43(1):50
Journal of experimental & clinical cancer research : CR 2024 Feb 17;43(1):50
N6-methyladenosine modification of B7-H3 mRNA promotes the development and progression of colorectal cancer.
Chen R, Su F, Zhang T, Wu D, Yang J, Guan Q, Chai C
iScience 2024 Feb 16;27(2):108956
iScience 2024 Feb 16;27(2):108956
TBX15 facilitates malignant progression of glioma by transcriptional activation of TXDNC5.
Ge Y, Jia B, Zhang P, Chen B, Liu L, Shi Y, Huang S, Liu X, Wang R, Xie Y, Li Z, Dong J
iScience 2024 Feb 16;27(2):108950
iScience 2024 Feb 16;27(2):108950
CREB3L4 promotes hepatocellular carcinoma progression and decreases sorafenib chemosensitivity by promoting RHEB-mTORC1 signaling pathway.
Jiang Z, Shi B, Zhang Y, Yu T, Cheng Y, Zhu J, Zhang G, Zhong M, Hu S, Ma X
iScience 2024 Feb 16;27(2):108843
iScience 2024 Feb 16;27(2):108843
NatD epigenetically activates FOXA2 expression to promote breast cancer progression by facilitating MMP14 expression.
Xing M, Yao B, Xu J, Lu P, Li Q, Wu D, Chen B, Wei J, Su L, Zhao Q
iScience 2024 Feb 16;27(2):108840
iScience 2024 Feb 16;27(2):108840
YTHDF2-mediated circYAP1 drives immune escape and cancer progression through activating YAP1/TCF4-PD-L1 axis.
Chen Z, Wang W, Hu S, Sun H, Chen C, Zhang Z, Sun X, Jia B, Hu J, Wang C, Liu Y, Sun Z
iScience 2024 Feb 16;27(2):108779
iScience 2024 Feb 16;27(2):108779
Inhibition of RIPK1 alleviating vascular smooth muscle cells osteogenic transdifferentiation via Runx2.
Li Y, Jie W, Qi Y, Mo M, Lian Y, Yin L, Huang H
iScience 2024 Feb 16;27(2):108766
iScience 2024 Feb 16;27(2):108766
Exploiting the Cullin E3 Ligase Adaptor Protein SKP1 for Targeted Protein Degradation.
Hong SH, Divakaran A, Osa A, Huang OW, Wertz IE, Nomura DK
ACS chemical biology 2024 Feb 16;19(2):442-450
ACS chemical biology 2024 Feb 16;19(2):442-450
Protein phosphatase 1 regulatory subunit 15 A promotes translation initiation and induces G2M phase arrest during cuproptosis in cancers.
Liu C, Chen L, Cong Y, Cheng L, Shuai Y, Lv F, Chen K, Song Y, Xing Y
Cell death & disease 2024 Feb 16;15(2):149
Cell death & disease 2024 Feb 16;15(2):149
Pro-ferroptotic signaling promotes arterial aging via vascular smooth muscle cell senescence.
Sun DY, Wu WB, Wu JJ, Shi Y, Xu JJ, Ouyang SX, Chi C, Shi Y, Ji QX, Miao JH, Fu JT, Tong J, Zhang PP, Zhang JB, Li ZY, Qu LF, Shen FM, Li DJ, Wang P
Nature communications 2024 Feb 16;15(1):1429
Nature communications 2024 Feb 16;15(1):1429
High-fat diet promotes prostate cancer metastasis via RPS27.
Li D, Zhou X, Xu W, Cai Y, Mu C, Zhao X, Tang T, Liang C, Yang T, Zheng J, Wei L, Ma B
Cancer & metabolism 2024 Feb 16;12(1):6
Cancer & metabolism 2024 Feb 16;12(1):6
Deciphering m6A signatures in hepatocellular carcinoma: Single-cell insights, immune landscape, and the protective role of IGFBP3.
Chen S, Liu J, Zhang S, Zhao L, Zhang J, Han P, Zhang Q, Liu Y, Wang F, Li J
Environmental toxicology 2024 Feb 16;
Environmental toxicology 2024 Feb 16;
DOPAMINE D4 RECEPTOR DOWN-REGULATES RENAL SODIUM CHLORIDE COTRANSPORTER VIA UBIQUITINATION-ASSOCIATED LYSOSOME DEGRADATION.
Zhang M, Liu M, Ren Z, Wang W, Upadhyay K, Asico LA, Armando I, Jia Y, Wang P, Xue Y, Wang X
bioRxiv : the preprint server for biology 2024 Feb 16;
bioRxiv : the preprint server for biology 2024 Feb 16;
Pharmacological inhibition of ICOS attenuates the protective effect of exercise on cardiac fibrosis induced by isoproterenol.
Peng Y, Qin D, Wang Y, Gao W, Xu X
European journal of pharmacology 2024 Feb 15;965:176327
European journal of pharmacology 2024 Feb 15;965:176327
Exploring the importance of m5c in the diagnosis and subtype classification of COPD using the GEO database.
Wu J, Li X, Kong D, Zheng X, Du W, Zhang Y, Jiao Y, Li X
Gene 2024 Feb 15;895:147987
Gene 2024 Feb 15;895:147987
Hic-5 regulates extracellular matrix-associated gene expression and cytokine secretion in cancer associated fibroblasts.
Xu W, Goreczny GJ, Forsythe I, Brennan G, Stowell T, Brock K, Capella B, Turner CE
Experimental cell research 2024 Feb 15;435(2):113930
Experimental cell research 2024 Feb 15;435(2):113930
A novel tsRNA-5008a promotes ferroptosis in cardiomyocytes that causes atrial structural remodeling predisposed to atrial fibrillation.
Xie L, Zhao Z, Xia H, Su S, He L, Huang Z, Li Y, Gao M, Chen J, Peng J, Ruan Y
Experimental cell research 2024 Feb 15;435(2):113923
Experimental cell research 2024 Feb 15;435(2):113923
YTHDF2 alleviates microglia activation via promoting circHIPK2 degradation.
Huang R, Sun M, Wang W, Yu X, Liu F
Journal of neuroimmunology 2024 Feb 15;387:578265
Journal of neuroimmunology 2024 Feb 15;387:578265
Disrupting the gut microbiota/metabolites axis by Di-(2-ethylhexyl) phthalate drives intestinal inflammation via AhR/NF-κB pathway in mice.
Cheng X, Chen J, Guo X, Cao H, Zhang C, Hu G, Zhuang Y
Environmental pollution (Barking, Essex : 1987) 2024 Feb 15;343:123232
Environmental pollution (Barking, Essex : 1987) 2024 Feb 15;343:123232
Methotrexate-based PROTACs as DHFR-specific chemical probes.
Rana S, Dranchak P, Dahlin JL, Lamy L, Li W, Oliphant E, Shrimp JH, Rajacharya GH, Tharakan R, Holland DO, Whitten AS, Wilson KM, Singh PK, Durum SK, Tao D, Rai G, Inglese J
Cell chemical biology 2024 Feb 15;31(2):221-233.e14
Cell chemical biology 2024 Feb 15;31(2):221-233.e14
Integrated network pharmacology and metabolomics reveal the action mechanisms of vincristine combined with celastrol against colon cancer.
Ning JY, Ma B, Huang JY, Han L, Shao YH, Wang FY
Journal of pharmaceutical and biomedical analysis 2024 Feb 15;239:115883
Journal of pharmaceutical and biomedical analysis 2024 Feb 15;239:115883
Synergistic and attenuated effects and molecular biological mechanisms of Shouhui Tongbian capsule in the treatment of slow transit constipation based on UPLC-MS/MS, network pharmacology and animal experimental validation.
Zhang N, Lv F, Xiao H, Yi B, Shao M, Liang H, Wang Y, Guo N, Yao J, Guan Y, Zhang G
Journal of pharmaceutical and biomedical analysis 2024 Feb 15;239:115846
Journal of pharmaceutical and biomedical analysis 2024 Feb 15;239:115846
Comprehensive analysis of the protein phosphatase 2A regulatory subunit B56ε in pan-cancer and its role and mechanism in hepatocellular carcinoma.
Wu HM, Huang YY, Xu YQ, Xiang WL, Yang C, Liu RY, Li D, Guo XF, Zhang ZB, Bei CH, Tan SK, Zhu XN
World journal of gastrointestinal oncology 2024 Feb 15;16(2):475-492
World journal of gastrointestinal oncology 2024 Feb 15;16(2):475-492
ACE2 improves endothelial cell function and reduces acute lung injury by downregulating FAK expression.
He Y, Gang B, Zhang M, Bai Y, Wan Z, Pan J, Liu J, Liu G, Gu W
International immunopharmacology 2024 Feb 15;128:111535
International immunopharmacology 2024 Feb 15;128:111535
Blocking brown adipocyte β(3)-adrenoceptor attenuates blood-spinal cord barrier impairment and chronic postsurgical pain in a rat model of preoperative stress.
Zhu J, Hou B, Rong H, Xu K, Jiang L, Yang S, Zhu H, Yang H, Jiao Y, Liu Y, Ni K, Ma Z
International immunopharmacology 2024 Feb 15;128:111530
International immunopharmacology 2024 Feb 15;128:111530
FTO attenuates LPS-induced acute kidney injury by inhibiting autophagy via regulating SNHG14/miR-373-3p/ATG7 axis.
Yang N, Yan N, Bai Z, Du S, Zhang J, Zhang L, Zhang Z
International immunopharmacology 2024 Feb 15;128:111483
International immunopharmacology 2024 Feb 15;128:111483
The TGFβ1/SMADs/Snail1 signaling axis mediates pericyte-derived fibrous scar formation after spinal cord injury.
Huang Y, Liu R, Meng T, Zhang B, Ma J, Liu X
International immunopharmacology 2024 Feb 15;128:111482
International immunopharmacology 2024 Feb 15;128:111482
Xingnaojing injection alleviates cerebral ischemia/reperfusion injury through regulating endoplasmic reticulum stress in Vivo and in Vitro.
Dong X, Li C, Yao Y, Liu F, Jiang P, Gao Y
Heliyon 2024 Feb 15;10(3):e25267
Heliyon 2024 Feb 15;10(3):e25267
Pterostilbene attenuates heart failure by inhibiting myocardial ferroptosis through SIRT1/GSK-3β/GPX4 signaling pathway.
Zhang F, Zeng Z, Zhang J, Li X, Yang W, Wei Y, Guo X
Heliyon 2024 Feb 15;10(3):e24562
Heliyon 2024 Feb 15;10(3):e24562
Eriocalyxin B alleviated ischemic cerebral injury by limiting microglia-mediated excessive neuroinflammation in mice.
Chen Y, Zhang C, Zhao L, Chen R, Zhang P, Li J, Zhang X, Zhang X
Experimental animals 2024 Feb 14;73(1):124-135
Experimental animals 2024 Feb 14;73(1):124-135
ZNF460-mediated circRPPH1 promotes TNBC progression through ITGA5-induced FAK/PI3K/AKT activation in a ceRNA manner.
Zhang C, Yu Z, Yang S, Liu Y, Song J, Mao J, Li M, Zhao Y
Molecular cancer 2024 Feb 14;23(1):33
Molecular cancer 2024 Feb 14;23(1):33
Comprehensive analysis of disulfidptosis-related genes: a prognosis model construction and tumor microenvironment characterization in clear cell renal cell carcinoma.
Yi B, Wei X, Liu D, Jing L, Xu S, Zhang M, Liang Z, Liu R, Zhang Z
Aging 2024 Feb 14;16(4):3647-3673
Aging 2024 Feb 14;16(4):3647-3673
3D Spheroids Facilitate Differentiation of Human Adipose-Derived Mesenchymal Stem Cells into Hepatocyte-Like Cells via p300-Mediated H3K56 Acetylation.
Yu Y, Huang H, Ye J, Li Y, Xie R, Zeng L, Huang Y, Zeng T, Luo D, Zhong J, Peng W
Stem cells translational medicine 2024 Feb 14;13(2):151-165
Stem cells translational medicine 2024 Feb 14;13(2):151-165
Microneme-located VP2 in Eimeria acervulina elicits effective protective immunity against infectious bursal disease virus.
Yu Y, Tang X, Duan C, Suo J, Crouch C, Zhang S, Liu X, Liu J, Bruton B, Tarpey I, Suo X
Infection and immunity 2024 Feb 13;92(2):e0045623
Infection and immunity 2024 Feb 13;92(2):e0045623
Aggresome formation promotes ASK1/JNK signaling activation and stemness maintenance in ovarian cancer.
Chen Y, Qiang Y, Fan J, Zheng Q, Yan L, Fan G, Song X, Zhang N, Lv Q, Xiong J, Wang J, Cao J, Liu Y, Xiong J, Zhang W, Li F
Nature communications 2024 Feb 13;15(1):1321
Nature communications 2024 Feb 13;15(1):1321
Human Parathyroid Hormone (1-34) accelerates skin wound healing through inducing cell migration via up-regulating the expression of Rac1.
Sun Q, Zhou L, Yu Z, Zhang J, Zhang C, Pi H
Cell division 2024 Feb 12;19(1):4
Cell division 2024 Feb 12;19(1):4
Orexin-A alleviates ferroptosis by activating the Nrf2/HO-1 signaling pathway in traumatic brain injury.
Kang J, Ren B, Huang L, Dong X, Xiong Q, Feng Z
Aging 2024 Feb 12;16(4):3404-3419
Aging 2024 Feb 12;16(4):3404-3419
A methylation-phosphorylation switch controls EZH2 stability and hematopoiesis.
Guo P, Lim RC, Rajawasam K, Trinh T, Sun H, Zhang H
eLife 2024 Feb 12;13
eLife 2024 Feb 12;13
Self-Healing Micro Arc Oxidation and Dicalcium Phosphate Dihydrate Double-Passivated Coating on Magnesium Membrane for Enhanced Bone Integration Repair.
Wu J, Shen Y, Wang P, Guo Z, Bai J, Wang X, Chen D, Lin X, Tang C
ACS biomaterials science & engineering 2024 Feb 12;10(2):1062-1076
ACS biomaterials science & engineering 2024 Feb 12;10(2):1062-1076
Jingfang Granule mitigates Coxsackievirus B3-induced myocardial damage by modulating mucolipin 1 expression.
Sun B, Lin L, Yao T, Yao J, Zhang G, Li Y, Li C
Journal of ethnopharmacology 2024 Feb 10;320:117396
Journal of ethnopharmacology 2024 Feb 10;320:117396
Jiawei Maxing Shigan Tang alleviates radiation-induced lung injury via TGF-β1/Smad signaling pathway mediated by regulatory T cells.
Wang M, Feng Y, Zhang P, Shen K, Su J, Zhong Y, Yang X, Lin S, Lu J
Journal of ethnopharmacology 2024 Feb 10;320:117389
Journal of ethnopharmacology 2024 Feb 10;320:117389
DNA hypomethylation-mediated upregulation of GADD45B facilitates airway inflammation and epithelial cell senescence in COPD.
Zhan Y, Huang Q, Deng Z, Chen S, Yang R, Zhang J, Zhang Y, Peng M, Wu J, Gu Y, Zeng Z, Xie J
Journal of advanced research 2024 Feb 10;
Journal of advanced research 2024 Feb 10;
Ferroptosis as a Potential Therapeutic Target for Reducing Inflammation and Corneal Scarring in Bacterial Keratitis.
Chen Q, Wang L, Wei Y, Xu X, Guo X, Liang Q
Investigative ophthalmology & visual science 2024 Feb 1;65(2):29
Investigative ophthalmology & visual science 2024 Feb 1;65(2):29
CP41, a novel curcumin analogue, induces apoptosis in endometrial cancer cells by activating the H3F3A/ proteasome-MAPK signaling pathway and enhancing oxidative stress.
Zhang MJ, Shi M, Yu Y, Wang H, Ou R, Ge RS
Life sciences 2024 Feb 1;338:122406
Life sciences 2024 Feb 1;338:122406
The role and mechanism of NLRP3 in wasp venom-induced acute kidney injury.
Li H, Gong J, Bian F, Yu F, Yuan H, Hu F
Toxicon : official journal of the International Society on Toxinology 2024 Feb 1;238:107570
Toxicon : official journal of the International Society on Toxinology 2024 Feb 1;238:107570
miR-6881-3p contributes to diminished ovarian reserve by regulating granulosa cell apoptosis by targeting SMAD4.
Ju W, Zhao S, Wu H, Yu Y, Li Y, Liu D, Lian F, Xiang S
Reproductive biology and endocrinology : RB&E 2024 Feb 1;22(1):17
Reproductive biology and endocrinology : RB&E 2024 Feb 1;22(1):17
Therapeutic application of human type 2 innate lymphoid cells via induction of granzyme B-mediated tumor cell death.
Li Z, Ma R, Tang H, Guo J, Shah Z, Zhang J, Liu N, Cao S, Marcucci G, Artis D, Caligiuri MA, Yu J
Cell 2024 Feb 1;187(3):624-641.e23
Cell 2024 Feb 1;187(3):624-641.e23
Down-expression of miR-494-3p in senescent osteocyte-derived exosomes inhibits osteogenesis and accelerates age-related bone loss via PTEN/PI3K/AKT pathway.
Yao C, Sun J, Luo W, Chen H, Chen T, Chen C, Zhang B, Zhang Y
Bone & joint research 2024 Feb 1;13(2):52-65
Bone & joint research 2024 Feb 1;13(2):52-65
Exploring the Osteogenic Potential of Zinc-Doped Magnesium Phosphate Cement (ZMPC): A Novel Material for Orthopedic Bone Defect Repair.
Liu Y, Yu L, Chen J, Li S, Wei Z, Guo W
Biomedicines 2024 Feb 1;12(2)
Biomedicines 2024 Feb 1;12(2)
LncRNA AFAP1-AS1 Promotes Oral Squamous Cell Carcinoma Development by Ubiquitin-Mediated Proteolysis.
Li BJ, Ren FH, Zhang C, Zhang XW, Jiao XH
International dental journal 2024 Dec;74(6):1277-1286
International dental journal 2024 Dec;74(6):1277-1286
Peptidylprolyl isomerase D circular RNA sensitizes breast cancer to trastuzumab through remodeling HER2 N4-acetylcytidine modification.
Wang S, Li Q, Wang Y, Li X, Feng X, Wei Y, Wang J, Zhou X
Journal of applied genetics 2024 Dec;65(4):797-807
Journal of applied genetics 2024 Dec;65(4):797-807
OGT-induced O-GlcNAcylation of NEK7 protein aggravates osteoarthritis progression by enhancing NEK7/NLRP3 axis.
He C, Wu Q, Zeng Z, Yang Y, He H, Hu M, Liu S
Autoimmunity 2024 Dec;57(1):2319202
Autoimmunity 2024 Dec;57(1):2319202
Identification of a novel nonsense mutation in α-galactosidase A that causes Fabry disease in a Chinese family.
Peng Y, Pan M, Wang Y, Shen Z, Xu J, Xiong F, Xiao H, Miao Y
Renal failure 2024 Dec;46(2):2362391
Renal failure 2024 Dec;46(2):2362391
Shen Shuai II recipe improves renal hypoxia to attenuate renal injury in 5/6 renal ablation/infarction rats and effect evaluation using blood oxygenation level-dependent functional magnetic resonance imaging.
Xu Y, Lu F, Wang M, Wang L, Ye C, Yang S, Wang C
Renal failure 2024 Dec;46(1):2338565
Renal failure 2024 Dec;46(1):2338565
Ginsenoside Rg1 mitigates cerebral ischaemia/reperfusion injury in mice by inhibiting autophagy through activation of mTOR signalling.
Xi ZC, Ren HG, Ai L, Wang Y, Liu MF, Qiu YF, Feng JL, Fu W, Bi QQ, Wang F, Xu HX
Acta pharmacologica Sinica 2024 Dec;45(12):2474-2486
Acta pharmacologica Sinica 2024 Dec;45(12):2474-2486
Engineered low-pathogenic Helicobacter pylori as orally tumor immunomodulators for the stimulation of systemic immune response.
Zeng Z, Sun Y, Jiang J, Xu X, Lin H, Li W, Zheng D, Huang Y, Zhao C
Biomaterials 2024 Dec;311:122672
Biomaterials 2024 Dec;311:122672
Comprehensive pan-cancer analysis unveils the significant prognostic value and potential role in immune microenvironment modulation of TRIB3.
Hu C, Li Q, Xiang L, Luo Y, Li S, An J, Yu X, Zhang G, Chen Y, Wang Y, Wang D
Computational and structural biotechnology journal 2024 Dec;23:234-250
Computational and structural biotechnology journal 2024 Dec;23:234-250
Downregulation of ABLIM3 confers to the metastasis of neuroblastoma via regulating the cell adhesion molecules pathway.
Gong B, Qu T, Zhang J, Jia Y, Song Z, Chen C, Yang J, Wang C, Liu Y, Jin Y, Cao W, Zhao Q
Computational and structural biotechnology journal 2024 Dec;23:1547-1561
Computational and structural biotechnology journal 2024 Dec;23:1547-1561
Coxiella burnetii effector CvpE maintains biogenesis of Coxiella-containing vacuoles by suppressing lysosome tubulation through binding PI(3)P and perturbing PIKfyve activity on lysosomes.
Zhao M, Zhang S, Wan W, Zhou C, Li N, Cheng R, Yu Y, Ouyang X, Zhou D, Jiao J, Xiong X
Virulence 2024 Dec;15(1):2350893
Virulence 2024 Dec;15(1):2350893
The mechanism of α2-macroglobulin against oxidative stress and promoting cell proliferation in intervertebral disc degeneration.
Liang H, Wang Y
Bioengineered 2024 Dec;15(1):2011638
Bioengineered 2024 Dec;15(1):2011638
The African swine fever virus MGF300-4L protein is associated with viral pathogenicity by promoting the autophagic degradation of IKKβ and increasing the stability of IκBα.
Wang T, Luo R, Zhang J, Lan J, Lu Z, Zhai H, Li LF, Sun Y, Qiu HJ
Emerging microbes & infections 2024 Dec;13(1):2333381
Emerging microbes & infections 2024 Dec;13(1):2333381
Effectiveness of a broad-spectrum bivalent mRNA vaccine against SARS-CoV-2 variants in preclinical studies.
Lu J, Tan S, Gu H, Liu K, Huang W, Yu Z, Lu G, Wu Z, Gao X, Zhao J, Yao Z, Yi F, Yang Y, Wang H, Hu X, Lu M, Li W, Zhou H, Yu H, Shan C, Lin J
Emerging microbes & infections 2024 Dec;13(1):2321994
Emerging microbes & infections 2024 Dec;13(1):2321994
Berberine chloride suppresses pancreatic adenocarcinoma proliferation and growth by targeting inflammation-related genes: an in silico analysis with in vitro and vivo validation.
Ruan LJ, Jiao JY, Cheng C, Zhang Y, Cao ZQ, He B, Chen Z
Cancer chemotherapy and pharmacology 2024 Aug;94(2):169-181
Cancer chemotherapy and pharmacology 2024 Aug;94(2):169-181
Inhibition of LSD1 via SP2509 attenuated the progression of rheumatoid arthritis.
Yu Z, Li P, Gao D, Hu Y, Xia F, Liu L, Liu J, Liu W, Zhang H
Immunologic research 2024 Aug;72(4):797-810
Immunologic research 2024 Aug;72(4):797-810
Characterization of circRNA expression profiles associated with non-Mendelian inheritance in feather growth of chickens.
Qiu M, Yu C, Zhu S, Hu C, Yang L, Song X, Xia B, Jiang X, Du H, Li Q, Zhang Z, Yang C
British poultry science 2024 Aug;65(4):371-377
British poultry science 2024 Aug;65(4):371-377
β-Elemene induced ferroptosis via TFEB-mediated GPX4 degradation in EGFR wide-type non-small cell lung cancer.
Zhao LP, Wang HJ, Hu D, Hu JH, Guan ZR, Yu LH, Jiang YP, Tang XQ, Zhou ZH, Xie T, Lou JS
Journal of advanced research 2024 Aug;62:257-272
Journal of advanced research 2024 Aug;62:257-272
Dapagliflozin attenuates LPS-induced myocardial injury by reducing ferroptosis.
Hu K, Jiang P, Hu J, Song B, Hou Y, Zhao J, Chen H, Xie J
Journal of bioenergetics and biomembranes 2024 Aug;56(4):361-371
Journal of bioenergetics and biomembranes 2024 Aug;56(4):361-371
Long noncoding RNA ANRIL alleviates hypoxia-induced pulmonary microvascular endothelial cell damage.
Qi Y, Chen M, Zhang T, Zhao B, Jin T, Yuan D
European journal of clinical investigation 2024 Aug;54(8):e14202
European journal of clinical investigation 2024 Aug;54(8):e14202
PD-L1 Expression Is Increased in LPS-Induced Acute Respiratory Distress Syndrome by PI3K-AKT-Egr-1/C/EBPδ Signaling Pathway.
Yan C, Chen J, Wang B, Wang J, Luo M, Tong J, Xu X, Zhang Q, Wang X
Inflammation 2024 Aug;47(4):1459-1478
Inflammation 2024 Aug;47(4):1459-1478
TRIM38 Induced in Respiratory Syncytial Virus-infected Cells Downregulates Type I Interferon Expression by Competing with TRIM25 to Bind RIG-I.
Sun Q, Han X, Meng L, Li H, Chen Y, Yin L, Wang C, Wang J, Li M, Gao X, Li W, Wei L, Ma C
Inflammation 2024 Aug;47(4):1328-1343
Inflammation 2024 Aug;47(4):1328-1343
MiR-425-5p suppression of Crebzf regulates oocyte aging via chromatin modification.
Jueraitetibaike K, Tang T, Ma R, Zhao S, Wu R, Yang Y, Huang X, Cheng X, Zhou C, Zhang H, Zheng L, Ge X, Chen L, Yao B
GeroScience 2024 Aug;46(4):3723-3742
GeroScience 2024 Aug;46(4):3723-3742
The classical D1 dopamine receptor antagonist SCH23390 is a functional sigma-1 receptor allosteric modulator.
Zhang GF, Zhu KL, Li Q, Zhang Y, Waddington JL, Du XD, Zhen XC
Acta pharmacologica Sinica 2024 Aug;45(8):1582-1590
Acta pharmacologica Sinica 2024 Aug;45(8):1582-1590
Isobavachalcone induces hepatotoxicity in zebrafish embryos and HepG2 cells via the System Xc(-)-GSH-GPX4 signaling pathway in ferroptosis response.
Ni X, Gao C, Zhu X, Zhang X, Fang Y, Hao Z
Journal of applied toxicology : JAT 2024 Aug;44(8):1139-1152
Journal of applied toxicology : JAT 2024 Aug;44(8):1139-1152
Environmentally relevant levels of Cd and Mo coexposure induces ferroptosis and excess ferritinophagy through AMPK/mTOR axis in duck myocardium.
Huang B, Nie G, Dai X, Cui T, Pu W, Zhang C
Environmental toxicology 2024 Aug;39(8):4196-4206
Environmental toxicology 2024 Aug;39(8):4196-4206
The combination of berberine and isoliquiritigenin synergistically improved adipose inflammation and obesity-induced insulin resistance.
Zhang XY, Yu L, Wang K, Wang M, Li P, Zheng ZG, Yang H
Phytotherapy research : PTR 2024 Aug;38(8):3839-3855
Phytotherapy research : PTR 2024 Aug;38(8):3839-3855
T-cell immunoglobulin and mucin 1 (TIM-1) mediates infection of Hantaan virus in Jurkat T cells.
Ma R, Zheng X, Gu T, Liu Z, Hou S, Sun D, Ding Y, Wang F, Ying Q, Ma X, Kang H, Liu R, Lian J, Wu X
Virus research 2024 Aug;346:199394
Virus research 2024 Aug;346:199394
Localized, highly efficient secretion of signaling proteins by migrasomes.
Jiao H, Li X, Li Y, Guo Y, Hu X, Sho T, Luo Y, Wang J, Cao H, Du W, Li D, Yu L
Cell research 2024 Aug;34(8):572-585
Cell research 2024 Aug;34(8):572-585
Obstructive Sleep Apnea Plasma-Derived Exosomes Mediate Cognitive Impairment Through Hippocampal Neuronal Cell Pyroptosis.
Chen Z, Shang Y, Ou Y, Shen C, Cao Y, Hu H, Yang R, Liu T, Liu Q, Song M, Zong D, Xiang X, Peng Y, Ouyang R
The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry 2024 Aug;32(8):922-939
The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry 2024 Aug;32(8):922-939
MUC16 can Predict the Pregnancy Outcomes in Human and Intraperitoneal Administration of MUC16 can Rescue Pregnancy Losses in Mouse Models.
Huang X, Lin H, Zhao Y, Wang P, Ying H, Zhang S, Liu L
Reproductive sciences (Thousand Oaks, Calif.) 2024 Aug;31(8):2354-2370
Reproductive sciences (Thousand Oaks, Calif.) 2024 Aug;31(8):2354-2370
Approaches to selective and potent inhibition of glioblastoma by vanadyl complexes: Inducing mitotic catastrophe and methuosis.
Xu S, Liu H, Li X, Zhao J, Wang J, Crans DC, Yang X
Journal of inorganic biochemistry 2024 Aug;257:112610
Journal of inorganic biochemistry 2024 Aug;257:112610
Characterization and noncovalent inhibition of the K63-deubiquitinase activity of SARS-cov-2 PLpro.
Liu X, Zheng M, Zhang H, Feng B, Li J, Zhang Y, Zhang J, Zhao N, Li C, Song N, Song B, Yang D, Chen J, Qi A, Zhao L, Luo C, Zang Y, Liu H, Li J, Zhang B, Zhou Y, Zheng J
Antiviral research 2024 Aug;228:105944
Antiviral research 2024 Aug;228:105944
Geniposide effectively safeguards HT22 cells against Aβ-induced damage by activating mitophagy via the PINK1/Parkin signaling pathway.
Ye J, Wu J, Ai L, Zhu M, Li Y, Yin D, Huang Q
Biochemical pharmacology 2024 Aug;226:116296
Biochemical pharmacology 2024 Aug;226:116296
Two Undescribed Coumarins from Notopterygium Incisum with Anti-Inflammatory Activity.
Hu YJ, Liu MD, Mu YT, Li CC, Zhao MH, Guo DL, Huang LJ, Gu YC, Xue QC, Deng Y
Chemistry & biodiversity 2024 Aug;21(8):e202401093
Chemistry & biodiversity 2024 Aug;21(8):e202401093
Bulk and single-cell transcriptome profiling identify potential cellular targets of the long noncoding RNA Gas5 in renal fibrosis.
Zhang X, Hu S, Xiang X, Li Z, Chen Z, Xia C, He Q, Jin J, Chen H
Biochimica et biophysica acta. Molecular basis of disease 2024 Aug;1870(6):167206
Biochimica et biophysica acta. Molecular basis of disease 2024 Aug;1870(6):167206
The dual effects of dexmedetomidine on intestinal barrier and intestinal motility during sepsis.
Cao YY, Wang ZH, Pan YJ, Qi YP, Chen Q, Qin XM, Wang T, Shen GG, Jiang XG, Lu WH
Surgery 2024 Aug;176(2):379-385
Surgery 2024 Aug;176(2):379-385
A novel surface marker CD49d promotes TNF expression in oyster agranulocytes by mediating the MAPK pathway.
Dong M, Wang W, Wu W, Cheng X, Cheng J, Wang L, Song L
Fish & shellfish immunology 2024 Aug;151:109702
Fish & shellfish immunology 2024 Aug;151:109702
CXCR4-mediated neutrophil dynamics in periodontitis.
Xu X, Li T, Tang J, Wang D, Zhou Y, Gou H, Li L, Xu Y
Cellular signalling 2024 Aug;120:111212
Cellular signalling 2024 Aug;120:111212
Lactate dehydrogenase B as a metabolism-related marker for immunotherapy in head and neck squamous cell carcinoma.
Xu X, Pan X, Fan Z, Xia J, Ren X
Cellular signalling 2024 Aug;120:111200
Cellular signalling 2024 Aug;120:111200
CKB Promotes Mitochondrial ATP Production by Suppressing Permeability Transition Pore.
He L, Lin J, Lu S, Li H, Chen J, Wu X, Yan Q, Liu H, Li H, Shi Y
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Aug;11(31):e2403093
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Aug;11(31):e2403093
Ginsenoside Rg1 Regulates Immune Microenvironment and Neurological Recovery After Spinal Cord Injury Through MYCBP2 Delivery via Neuronal Cell-Derived Extracellular Vesicles.
Rong Y, Wang J, Hu T, Shi Z, Lang C, Liu W, Cai W, Sun Y, Zhang F, Zhang W
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Aug;11(31):e2402114
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Aug;11(31):e2402114
Reversing MET-Mediated Resistance in Oncogene-Driven NSCLC by MET-Activated Wnt Condensative Prodrug.
Liu N, Zheng X, Yan J, Jiang A, Yao Y, He W
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Aug;11(30):e2400603
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Aug;11(30):e2400603
Inorganic Biomaterials Shape the Transcriptome Profile to Induce Endochondral Differentiation.
Murali A, Brokesh AM, Cross LM, Kersey AL, Jaiswal MK, Singh I, Gaharwar A
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Aug;11(29):e2402468
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Aug;11(29):e2402468
Preventive effects of lactoferrin on acute alcohol-induced liver injury via iron chelation and regulation of iron metabolism.
Guan S, Zhang S, Liu M, Guo J, Chen Y, Shen X, Deng X, Lu J
Journal of dairy science 2024 Aug;107(8):5316-5329
Journal of dairy science 2024 Aug;107(8):5316-5329
Nicotinamide metabolism face-off between macrophages and fibroblasts manipulates the microenvironment in gastric cancer.
Jiang Y, Wang Y, Chen G, Sun F, Wu Q, Huang Q, Zeng D, Qiu W, Wang J, Yao Z, Liang B, Li S, Wu J, Huang N, Wang Y, Chen J, Zhai X, Huang L, Xu B, Yamamoto M, Tsukamoto T, Nomura S, Liao W, Shi M
Cell metabolism 2024 Aug 6;36(8):1806-1822.e11
Cell metabolism 2024 Aug 6;36(8):1806-1822.e11
Hepatitis B virus core protein as a Rab-GAP suppressor driving liver disease progression.
Su Y, Bu F, Zhu Y, Yang L, Wu Q, Zheng Y, Zhao J, Yu L, Jiang N, Wang Y, Wu J, Xie Y, Zhang X, Gao Y, Lan K, Deng Q
Science bulletin 2024 Aug 30;69(16):2580-2595
Science bulletin 2024 Aug 30;69(16):2580-2595
A positive FOXP3/lncRNA SNHG1 feedback axis ameliorates cardiomyocytes hypertrophy by negatively regulating Parkin-mediated mitophagy.
Zhang J, Luo X, Yang X, Wang B, Zheng L, Yan S
International immunopharmacology 2024 Aug 20;137:112526
International immunopharmacology 2024 Aug 20;137:112526
Wedelolactone suppresses breast cancer growth and metastasis via regulating TGF-β1/Smad signaling pathway.
Li H, Hou M, Zhang P, Ren L, Guo Y, Zou L, Cao J, Bai Z
The Journal of pharmacy and pharmacology 2024 Aug 2;76(8):1038-1050
The Journal of pharmacy and pharmacology 2024 Aug 2;76(8):1038-1050
Cellular senescence-Related genes define the immune microenvironment and molecular characteristics in severe asthma patients.
Lin Q, Zheng Z, Ni H, Xu Y, Nie H
Gene 2024 Aug 15;919:148502
Gene 2024 Aug 15;919:148502
Exploration and validation of therapeutic molecules for rheumatoid arthritis based on ferroptosis-related genes.
Aihaiti Y, Zheng H, Cai Y, Tuerhong X, Kaerman M, Wang F, Xu P
Life sciences 2024 Aug 15;351:122780
Life sciences 2024 Aug 15;351:122780
Multi-omics and chemical profiling approaches to understand the material foundation and pharmacological mechanism of sophorae tonkinensis radix et rhizome-induced liver injury in mice.
Rao SW, Liu CJ, Liang D, Duan YY, Chen ZH, Li JJ, Pang HQ, Zhang FX, Shi W
Journal of ethnopharmacology 2024 Aug 10;330:118224
Journal of ethnopharmacology 2024 Aug 10;330:118224
Leonurus japonicus Houtt. modulates neuronal apoptosis in intracerebral hemorrhage: Insights from network pharmacology and molecular docking.
Wu JW, Gao W, Shen LP, Chen YL, Du SQ, Du ZY, Zhao XD, Lu XJ
Journal of ethnopharmacology 2024 Aug 10;330:118223
Journal of ethnopharmacology 2024 Aug 10;330:118223
Rosmarinic acid alleviates toosendanin-induced liver injury through restoration of autophagic flux and lysosomal function by activating JAK2/STAT3/CTSC pathway.
Luo L, Lin J, Chen S, Ni J, Peng H, Shen F, Huang Z
Journal of ethnopharmacology 2024 Aug 10;330:118196
Journal of ethnopharmacology 2024 Aug 10;330:118196
USP7 cardiomyocyte specific knockout causes disordered mitochondrial biogenesis and dynamics and early neonatal lethality in mice.
Yan M, Mei Y, Zhang T, Liu Z, Su L, Xiao Y, Zhong X, Lu Y
International journal of cardiology 2024 Aug 1;408:132149
International journal of cardiology 2024 Aug 1;408:132149
METTL3-mediated upregulation of FAM135B promotes EMT of esophageal squamous cell carcinoma via regulating the Wnt/β-catenin pathway.
Zhang TT, Yi W, Dong DZ, Ren ZY, Zhang Y, Du F
American journal of physiology. Cell physiology 2024 Aug 1;327(2):C329-C340
American journal of physiology. Cell physiology 2024 Aug 1;327(2):C329-C340
Fusobacterium nucleatum induces oxaliplatin resistance by inhibiting ferroptosis through E-cadherin/β-catenin/GPX4 axis in colorectal cancer.
Li B, Wei Z, Wang Z, Xu F, Yang J, Lin B, Chen Y, Wenren H, Wu L, Guo X, Liu Y, Wei Y
Free radical biology & medicine 2024 Aug 1;220:125-138
Free radical biology & medicine 2024 Aug 1;220:125-138
The use of human iPSC-derived alveolar organoids to explore SARS-CoV-2 variant infections and host responses.
Gandikota C, Vaddadi K, Sivasami P, Huang C, Liang Y, Pushparaj S, Deng X, Channappanava R, Metcalf JP, Liu L
Journal of medical virology 2024 Apr;96(4):e29579
Journal of medical virology 2024 Apr;96(4):e29579
Statins Prevent the Deleterious Consequences of Placental Chemerin Upregulation in Preeclampsia.
Tan L, Kluivers ACM, Cruz-López EO, Broekhuizen M, Chen Z, Neuman RI, Schoenmakers S, Ruijgrok L, van de Velde D, de Winter BCM, van den Bogaerdt AJ, Lu X, Danser AHJ, Verdonk K
Hypertension (Dallas, Tex. : 1979) 2024 Apr;81(4):861-875
Hypertension (Dallas, Tex. : 1979) 2024 Apr;81(4):861-875
YAP1-activated ZNF131 promotes hepatocellular carcinoma cell proliferation through transcriptional regulation of PAIP1.
Yin G, Jia S, Zhang Y, Xian Y, Guo Y, Liu Q
Archives of biochemistry and biophysics 2024 Apr;754:109921
Archives of biochemistry and biophysics 2024 Apr;754:109921
RAE1 promotes gastric carcinogenesis and epithelial-mesenchymal transition.
Dong W, Li X, Cheng L, Yang J, Zhao Z, Qiang X, Li P, Wu J, Guo L
Archives of biochemistry and biophysics 2024 Apr;754:109896
Archives of biochemistry and biophysics 2024 Apr;754:109896
Endothelial H(2)S-AMPK dysfunction upregulates the angiocrine factor PAI-1 and contributes to lung fibrosis.
Chen X, Wang H, Wu C, Li X, Huang X, Ren Y, Pu Q, Cao Z, Tang X, Ding BS
Redox biology 2024 Apr;70:103038
Redox biology 2024 Apr;70:103038
The LINC complex ensures accurate centrosome positioning during prophase.
Lima JT, Pereira AJ, Ferreira JG
Life science alliance 2024 Apr;7(4)
Life science alliance 2024 Apr;7(4)
Knockout of Shcbp1 sensitizes immunotherapy by regulating α-SMA positive cancer-associated fibroblasts.
Gu Q, Ma Z, Wang Q, Dai Y, Shi W, Jiao Z
Molecular carcinogenesis 2024 Apr;63(4):601-616
Molecular carcinogenesis 2024 Apr;63(4):601-616
Human milk exosome-derived circDNAJB6 improves bronchopulmonary dysplasia model by promoting DNAJB6 gene transcription.
Li Y, Yu B, Li H, Hou W, Yin J, Zhou Y, Yu Z
Journal of bioenergetics and biomembranes 2024 Apr;56(2):171-180
Journal of bioenergetics and biomembranes 2024 Apr;56(2):171-180
Cytoplasmic localization of SETDB1‑induced Warburg effect via c‑MYC‑LDHA axis enhances migration and invasion in breast carcinoma.
Yang W, Wei Y, Wang T, Xu Y, Jin X, Qian H, Yang S, He S
International journal of molecular medicine 2024 Apr;53(4)
International journal of molecular medicine 2024 Apr;53(4)
A mutation in TBXT causes congenital vertebral malformations in humans and mice.
Chen S, Lei Y, Yang Y, Liu C, Kuang L, Jin L, Finnell RH, Yang X, Wang H
Journal of genetics and genomics = Yi chuan xue bao 2024 Apr;51(4):433-442
Journal of genetics and genomics = Yi chuan xue bao 2024 Apr;51(4):433-442
PEDF protects retinal pigment epithelium from ferroptosis and ameliorates dry AMD-like pathology in a murine model.
Xiang W, Li L, Zhao Q, Zeng Y, Shi J, Chen Z, Gao G, Lai K
GeroScience 2024 Apr;46(2):2697-2714
GeroScience 2024 Apr;46(2):2697-2714
SIBP-03, a novel anti-HER3 antibody, exerts antitumor effects and synergizes with EGFR- and HER2-targeted drugs.
Li WJ, Xie CY, Zhu X, Tang J, Wang L, Lou LG
Acta pharmacologica Sinica 2024 Apr;45(4):857-866
Acta pharmacologica Sinica 2024 Apr;45(4):857-866
Chemokine CCL2 promotes cardiac regeneration and repair in myocardial infarction mice via activation of the JNK/STAT3 axis.
Wang W, Chen XK, Zhou L, Wang F, He YJ, Lu BJ, Hu ZG, Li ZX, Xia XW, Wang WE, Zeng CY, Li LP
Acta pharmacologica Sinica 2024 Apr;45(4):728-737
Acta pharmacologica Sinica 2024 Apr;45(4):728-737
Effects of down-regulated carbonic anhydrase 8 on cell survival and glucose metabolism in human colorectal cancer cell lines.
Wu CY, Yu JY, Chen YS, Chang HP, Hsieh BY, Lin YH, Ma CY, Tsai SF, Hsieh M
Cell biochemistry and function 2024 Apr;42(3):e4001
Cell biochemistry and function 2024 Apr;42(3):e4001
LncRNA HOTTIP regulates TLR4 promoter methylation by recruiting H3K4 methyltransferase MLL1 to affect apoptosis and inflammatory response of fibroblast-like synoviocyte in rheumatoid arthritis.
Wang G, Xu YL, Zhang XH, Tang L, Li Y
The Kaohsiung journal of medical sciences 2024 Apr;40(4):335-347
The Kaohsiung journal of medical sciences 2024 Apr;40(4):335-347
Gallic acid promotes ferroptosis in hepatocellular carcinoma via inactivating Wnt/β-catenin signaling pathway.
Xie J, Wang H, Xie W, Liu Y, Chen Y
Naunyn-Schmiedeberg's archives of pharmacology 2024 Apr;397(4):2437-2445
Naunyn-Schmiedeberg's archives of pharmacology 2024 Apr;397(4):2437-2445
Toosendanin induces hepatotoxicity by restraining autophagy and lysosomal function through inhibiting STAT3/CTSC axis.
Luo L, Ni J, Zhang J, Lin J, Chen S, Shen F, Huang Z
Toxicology letters 2024 Apr;394:102-113
Toxicology letters 2024 Apr;394:102-113
Ganoderic acids alleviate atherosclerosis by inhibiting macrophage M1 polarization via TLR4/MyD88/NF-κB signaling pathway.
Quan YZ, Ma A, Ren CQ, An YP, Qiao PS, Gao C, Zhang YK, Li XW, Lin SM, Li NN, Chen DL, Pan Y, Zhou H, Lin DM, Lin SQ, Li M, Yang BX
Atherosclerosis 2024 Apr;391:117478
Atherosclerosis 2024 Apr;391:117478
Blood RNA-sequencing analysis in acrylamide-induced neurotoxicity and depressive symptoms in rats.
Chen YT, Lin TJ, Hung CY
Environmental toxicology 2024 Apr;39(4):2316-2325
Environmental toxicology 2024 Apr;39(4):2316-2325
Excess iron accumulation mediated senescence in diabetic kidney injury.
Cheng X, Li Y, Chen L, Jiang C, Peng S, Yao P, Tang Y
Journal of biochemical and molecular toxicology 2024 Apr;38(4):e23683
Journal of biochemical and molecular toxicology 2024 Apr;38(4):e23683
Pimpinellin ameliorates macrophage inflammation by promoting RNF146-mediated PARP1 ubiquitination.
Yang L, Du M, Liu K, Wang P, Zhu J, Li F, Wang Z, Huang K, Liang M
Phytotherapy research : PTR 2024 Apr;38(4):1783-1798
Phytotherapy research : PTR 2024 Apr;38(4):1783-1798
Acteoside ameliorates learning and memory impairment in APP/PS1 transgenic mice by increasing Aβ degradation and inhibiting tau hyperphosphorylation.
Gao L, Wang D, Ren J, Tan X, Chen J, Kong Z, Nie Y, Yan M
Phytotherapy research : PTR 2024 Apr;38(4):1735-1744
Phytotherapy research : PTR 2024 Apr;38(4):1735-1744
Inhibiting RIPK1-driven neuroinflammation and neuronal apoptosis mitigates brain injury following experimental subarachnoid hemorrhage.
Wu Y, Xu Y, Sun J, Dai K, Wang Z, Zhang J
Experimental neurology 2024 Apr;374:114705
Experimental neurology 2024 Apr;374:114705
Enhanced osteogenic and antibacterial properties of titanium implant surface modified with Zn-incorporated nanowires: Preclinical in vitro and in vivo investigations.
Shen Z, Xu Y, Qian XN, Zhou YH, Zhou Y, Zhou JY, Liu Y, Zhang SM, Qiu J
Clinical oral implants research 2024 Apr;35(4):427-442
Clinical oral implants research 2024 Apr;35(4):427-442
Transcriptome analysis reveals therapeutic potential of NAMPT in protecting against abdominal aortic aneurysm in human and mouse.
Ouyang Y, Hong Y, Mai C, Yang H, Wu Z, Gao X, Zeng W, Deng X, Liu B, Zhang Y, Fu Q, Huang X, Liu J, Li X
Bioactive materials 2024 Apr;34:17-36
Bioactive materials 2024 Apr;34:17-36
METTL3-mediated RanGAP1 promotes colorectal cancer progression through the MAPK pathway by recruiting YTHDF1.
Yang R, Yang C, Su D, Song Y, Min J, Qian Z, Shen X, Li J, Su H
Cancer gene therapy 2024 Apr;31(4):562-573
Cancer gene therapy 2024 Apr;31(4):562-573
Neuroinvasive virus facilitates viral replication by employing lipid droplets to reduce arachidonic acid-induced ferroptosis.
Zhao J, Wang Q, Liu Z, Zhang M, Li J, Fu ZF, Zhao L, Zhou M
The Journal of biological chemistry 2024 Apr;300(4):107168
The Journal of biological chemistry 2024 Apr;300(4):107168
Deep-targeted gene sequencing reveals ARID1A mutation as an important driver of glioblastoma.
Xiao M, Cui X, Xu C, Xin L, Zhao J, Yang S, Hong B, Tan Y, Zhang J, Li X, Li J, Kang C, Fang C
CNS neuroscience & therapeutics 2024 Apr;30(4):e14698
CNS neuroscience & therapeutics 2024 Apr;30(4):e14698
Carpesii fructus extract exhibits neuroprotective effects in cellular and Caenorhabditis elegans models of Parkinson's disease.
Zhu FD, Wang BD, Qin DL, Su XH, Yu L, Wu JM, Law BY, Guo MS, Yu CL, Zhou XG, Wu AG
CNS neuroscience & therapeutics 2024 Apr;30(4):e14515
CNS neuroscience & therapeutics 2024 Apr;30(4):e14515
Circular RNA PTP4A2 regulates microglial polarization through STAT3 to promote neuroinflammation in ischemic stroke.
Wang X, Zhang S, Lv B, Chen H, Zhang W, Dong L, Bao L, Wang M, Wang Y, Mao W, Cui L, Pang Y, Wang F, Yan F, Zhang Z, Cui G
CNS neuroscience & therapeutics 2024 Apr;30(4):e14512
CNS neuroscience & therapeutics 2024 Apr;30(4):e14512
Anti-PD-1 treatment protects against seizure by suppressing sodium channel function.
Yang Y, Chen Z, Zhou J, Jiang S, Wang G, Wan L, Yu J, Jiang M, Wang Y, Hu J, Liu X, Wang Y
CNS neuroscience & therapeutics 2024 Apr;30(4):e14504
CNS neuroscience & therapeutics 2024 Apr;30(4):e14504
Pleiotrophin inhibited chondrogenic differentiation potential of dental pulp stem cells.
Liu C, Zhang L, Zheng X, Zhu J, Jin L, Gao R
Oral diseases 2024 Apr;30(3):1439-1450
Oral diseases 2024 Apr;30(3):1439-1450
RUNX2 mutation inhibits the cellular senescence of dental follicle cells via ERK signalling pathway.
Ji L, Li J, Liu D, Qiao Y, Zhao W, Liu Y, Zheng S
Oral diseases 2024 Apr;30(3):1337-1349
Oral diseases 2024 Apr;30(3):1337-1349
Trk-fused gene plays a critical role in diet-induced adipose tissue expansion and is also involved in thyroid hormone action.
Yamamotoya T, Ohata Y, Akasaka Y, Hasei S, Inoue MK, Nakatsu Y, Kanna M, Yamazaki H, Kushiyama A, Fujishiro M, Ono H, Sakoda H, Yamada T, Ishihara H, Asano T
PNAS nexus 2024 Apr;3(4):pgae150
PNAS nexus 2024 Apr;3(4):pgae150
UBE2J1 promotes ALV-A proviral DNA synthesis through the STAT3/IRF1 signaling pathway.
Wang X, Zheng S, Fang C, Liang X, Yang Y
Veterinary microbiology 2024 Apr;291:110012
Veterinary microbiology 2024 Apr;291:110012
Hepatocyte-derived exosomes deliver the lncRNA CYTOR to hepatic stellate cells and promote liver fibrosis.
Xu W, Mo W, Han D, Dai W, Xu X, Li J, Xu X
Journal of cellular and molecular medicine 2024 Apr;28(8):e18234
Journal of cellular and molecular medicine 2024 Apr;28(8):e18234
Bilirubin ameliorates osteoarthritis via activating Nrf2/HO-1 pathway and suppressing NF-κB signalling.
Zhao X, Duan B, Wu J, Huang L, Dai S, Ding J, Sun M, Lin X, Jiang Y, Sun T, Lu R, Huang H, Lin G, Chen R, Yao Q, Kou L
Journal of cellular and molecular medicine 2024 Apr;28(7):e18173
Journal of cellular and molecular medicine 2024 Apr;28(7):e18173
Rapamycin inhibits B16 melanoma cell viability invitro and invivo by inducing autophagy and inhibiting the mTOR/p70‑S6k pathway.
Wang P, Zhang H, Guo K, Liu C, Chen S, Pu B, Chen S, Feng T, Jiao H, Gao C
Oncology letters 2024 Apr;27(4):140
Oncology letters 2024 Apr;27(4):140
Lipin-1 deficiency deteriorates defect of fatty acid β-oxidation and lipid-related kidney damage in diabetic kidney disease.
Lin S, Wang L, Jia Y, Sun Y, Qiao P, Quan Y, Liu J, Hu H, Yang B, Zhou H
Translational research : the journal of laboratory and clinical medicine 2024 Apr;266:1-15
Translational research : the journal of laboratory and clinical medicine 2024 Apr;266:1-15
Characterization and function of PTEN-induced putative kinase 1 (PINK1) in process of Zinc alleviates hepatic lipid deposition of yellow catfish (Pelteobagrus fulvidraco).
Xiao L, Chen B, Chen C, Xiao F, Li M, Zhuang M, Dai Y, Wu K
International journal of biological macromolecules 2024 Apr;265(Pt 2):131156
International journal of biological macromolecules 2024 Apr;265(Pt 2):131156
FXR1 stabilizes SNORD63 to regulate blood-tumor barrier permeability through SNORD63 mediated 2'-O-methylation of POU6F1.
Liang C, Zhai B, Wei D, Niu B, Ma J, Yao Y, Lin Y, Liu Y, Liu X, Wang P
International journal of biological macromolecules 2024 Apr;265(Pt 1):130642
International journal of biological macromolecules 2024 Apr;265(Pt 1):130642
CircNOP14 increases the radiosensitivity of hepatocellular carcinoma via inhibition of Ku70-dependent DNA damage repair.
Lin L, Hu P, Luo M, Chen X, Xiao M, Zhong Z, Peng S, Chen G, Yang G, Zhang F, Zhang Y
International journal of biological macromolecules 2024 Apr;264(Pt 2):130541
International journal of biological macromolecules 2024 Apr;264(Pt 2):130541
VDRA downregulate β-catenin/Smad3 and DNA damage and repair associated with improved prognosis in ccRCC patients.
Wang P, Nie J, Li J, Ye C, Chen J, Zhang Z, Li B
International journal of biological macromolecules 2024 Apr;263(Pt 2):130405
International journal of biological macromolecules 2024 Apr;263(Pt 2):130405
Chloroxine inhibits pancreatic cancer progression through targeted antagonization of the PI3K/AKT/mTOR signaling pathway.
Lin M, Xiao Y, Dai Y, Mao Y, Xu L, Zhang Q, Chen Z
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 2024 Apr;26(4):951-965
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 2024 Apr;26(4):951-965
Theileria annulata subtelomere-encoded variable secreted protein-TA05560 interacts with bovine RNA binding motif protein 39 (RBM39).
Ma Q, Han Y, Fu Y, Teng G, Wang X, Liu J, Li Z
Acta tropica 2024 Apr;252:107133
Acta tropica 2024 Apr;252:107133
TGF-β2-induced alterations of m6A methylation in hTERT RPE-1 cells.
Li X, Zhao X, Yin R, Yuan M, Zhang Y, Li X
Experimental eye research 2024 Apr;241:109839
Experimental eye research 2024 Apr;241:109839
Excessive processing and acetylation of OPA1 aggravate age-related hearing loss via the dysregulation of mitochondrial dynamics.
Zhang A, Pan Y, Wang H, Ding R, Zou T, Guo D, Shen Y, Ji P, Huang W, Wen Q, Wang Q, Hu H, Wu J, Xiang M, Ye B
Aging cell 2024 Apr;23(4):e14091
Aging cell 2024 Apr;23(4):e14091
TuBG1 promotes hepatocellular carcinoma via ATR/P53-apoptosis and cycling pathways.
Zhang Y, Wang ZZ, Han AQ, Yang MY, Zhu LX, Pan FM, Wang Y
Hepatobiliary & pancreatic diseases international : HBPD INT 2024 Apr;23(2):195-209
Hepatobiliary & pancreatic diseases international : HBPD INT 2024 Apr;23(2):195-209
Cevanine-type alkaloids from the bulbs of Fritillaria unibracteata var. wabuensis and their antifibrotic activities in vitro.
Fu L, Tian W, Bao MY, Liu Z, Ren WJ, Liu J, Zhang W, Zhang Z, Gao J, Bai LP, Jiang ZH, Zhu GY
Phytochemistry 2024 Apr;220:114018
Phytochemistry 2024 Apr;220:114018
Optogenetic manipulation of lysosomal physiology and autophagy-dependent clearance of amyloid beta.
Zeng W, Li C, Wu R, Yang X, Wang Q, Lin B, Wei Y, Li H, Shan G, Qu L, Cang C
PLoS biology 2024 Apr;22(4):e3002591
PLoS biology 2024 Apr;22(4):e3002591
Pseudorabies virus gM and its homologous proteins in herpesviruses induce mitochondria-related apoptosis involved in viral pathogenicity.
Zhou Q, Shi D, Tang YD, Zhang L, Hu B, Zheng C, Huang L, Weng C
PLoS pathogens 2024 Apr;20(4):e1012146
PLoS pathogens 2024 Apr;20(4):e1012146
African swine fever virus pB318L, a trans-geranylgeranyl-diphosphate synthase, negatively regulates cGAS-STING and IFNAR-JAK-STAT signaling pathways.
Liu X, Chen H, Ye G, Liu H, Feng C, Chen W, Hu L, Zhou Q, Zhang Z, Li J, Zhang X, He X, Guan Y, Wu Z, Zhao D, Bu Z, Weng C, Huang L
PLoS pathogens 2024 Apr;20(4):e1012136
PLoS pathogens 2024 Apr;20(4):e1012136
Clinical and molecular characterization of 10 Chinese children with congenital adrenal hyperplasia due to 11beta-hydroxylase deficiency.
Lu WL, Ma XY, Zhang J, Wang JQ, Zhang TT, Ye L, Xiao Y, Dong ZY, Wang W, Sun SY, Li CY, Hu RG, Ning G, Zhang LD
World journal of pediatrics : WJP 2024 Apr;20(4):422-433
World journal of pediatrics : WJP 2024 Apr;20(4):422-433
Person-specific differences in ubiquitin-proteasome mediated proteostasis in human neurons.
Hsieh YC, Augur ZM, Arbery M, Ashour N, Barrett K, Pearse RV 2nd, Tio ES, Duong DM, Felsky D, De Jager PL, Bennett DA, Seyfried NT, Young-Pearse TL
Alzheimer's & dementia : the journal of the Alzheimer's Association 2024 Apr;20(4):2952-2967
Alzheimer's & dementia : the journal of the Alzheimer's Association 2024 Apr;20(4):2952-2967
DOCK2 Promotes Atherosclerosis by Mediating the Endothelial Cell Inflammatory Response.
Qian G, Adeyanju O, Cai D, Tucker TA, Idell S, Chen SY, Guo X
The American journal of pathology 2024 Apr;194(4):599-611
The American journal of pathology 2024 Apr;194(4):599-611
Nanoreceptors promote mutant p53 protein degradation by mimicking selective autophagy receptors.
Huang X, Cao Z, Qian J, Ding T, Wu Y, Zhang H, Zhong S, Wang X, Ren X, Zhang W, Xu Y, Yao G, Wang X, Yang X, Wen L, Zhang Y
Nature nanotechnology 2024 Apr;19(4):545-553
Nature nanotechnology 2024 Apr;19(4):545-553
Platycodon grandiflorus polysaccharide inhibits the inflammatory response of 3D4/21 cells infected with PCV2.
Guo X, Zhao X, Li L, Jiang M, Zhou A, Gao Y, Zheng P, Liu J, Zhao X
Microbial pathogenesis 2024 Apr;189:106592
Microbial pathogenesis 2024 Apr;189:106592
Identification and validation of an immunotherapeutic signature for colon cancer based on the regulatory patterns of ferroptosis and their association with the tumor microenvironment.
Liu Y, Zhao J, Huang B, Liang Y, Jiang G, Zhou X, Chen Y, He T, Zheng M, Huang Z
Biochimica et biophysica acta. Molecular cell research 2024 Apr;1871(4):119698
Biochimica et biophysica acta. Molecular cell research 2024 Apr;1871(4):119698
GDI2 deletion alleviates neurodegeneration and memory loss in the 5xFAD mice model of Alzheimer's disease.
Wang M, He X, Li J, Han D, You P, Yu H, Wang L, Su B
Biochimica et biophysica acta. Molecular basis of disease 2024 Apr;1870(4):167093
Biochimica et biophysica acta. Molecular basis of disease 2024 Apr;1870(4):167093
Spermidine ameliorates osteoarthritis via altering macrophage polarization.
Ou Q, Tang S, Zhu J, Xue S, Huang H, Zhao Y, Cai Y, Wu C, Chen J, Ruan G, Ding C
Biochimica et biophysica acta. Molecular basis of disease 2024 Apr;1870(4):167083
Biochimica et biophysica acta. Molecular basis of disease 2024 Apr;1870(4):167083
MT-TN mutations lead to progressive mitochondrial encephalopathy and promotes mitophagy.
Duan H, Pan C, Wu T, Peng J, Yang L
Biochimica et biophysica acta. Molecular basis of disease 2024 Apr;1870(4):167043
Biochimica et biophysica acta. Molecular basis of disease 2024 Apr;1870(4):167043
LCP1-mediated cytoskeleton alterations involve in arsenite-triggered malignant phenotype of human immortalized prostate stromal cells.
Yang Y, Zhou M, Huang Y, Ye X, Mo Y, Huang Y, Wang S
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2024 Apr;186:114548
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2024 Apr;186:114548
Ginsenoside Rb1 alleviates 3-MCPD-induced renal cell pyroptosis by activating mitophagy.
Zhang R, Guan S, Meng Z, Zhang D, Lu J
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2024 Apr;186:114522
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2024 Apr;186:114522
Bisphenol S impairs mitochondrial function by targeting Myo19/oxidative phosphorylation pathway contributing to axonal and dendritic injury.
Zhang X, Gong H, Zhao Y, Wu Y, Cheng J, Song Y, Wang B, Qin Y, Sun M
Environment international 2024 Apr;186:108643
Environment international 2024 Apr;186:108643
Methylmercury induces inflammatory response and autophagy in microglia through the activation of NLRP3 inflammasome.
Li X, Ma K, Tian T, Pang H, Liu T, Li M, Li J, Luo Z, Hu H, Hou S, Yu J, Hou Q, Song X, Zhao C, Du H, Li J, Du Z, Jin M
Environment international 2024 Apr;186:108631
Environment international 2024 Apr;186:108631
Trilobatin attenuates cerebral ischaemia/reperfusion-induced blood-brain barrier dysfunction by targeting matrix metalloproteinase 9: The legend of a food additive.
Feng L, Li Y, Lin M, Xie D, Luo Y, Zhang Y, He Z, Gong Q, Zhun ZY, Gao J
British journal of pharmacology 2024 Apr;181(7):1005-1027
British journal of pharmacology 2024 Apr;181(7):1005-1027
Melittin induces autophagy to alleviate chronic renal failure in 5/6-nephrectomized rats and angiotensin II-induced damage in podocytes.
Zhang Y, Xu H, Qiao H, Zhao Y, Jiang M
Nutrition research and practice 2024 Apr;18(2):210-222
Nutrition research and practice 2024 Apr;18(2):210-222
Iron overload increases the sensitivity of endometriosis stromal cells to ferroptosis via a PRC2-independent function of EZH2.
Luo Y, Li L, Hu Q, Zhang Z, Liu F, Peng Y, Zou Y, Chen L
The international journal of biochemistry & cell biology 2024 Apr;169:106553
The international journal of biochemistry & cell biology 2024 Apr;169:106553
AKT2 deficiency alleviates doxorubicin-induced cardiac injury via alleviating oxidative stress in cardiomyocytes.
Chen J, Xu X, Shao Y, Bian X, Li R, Zhang Y, Xiao Y, Lu M, Jiang Q, Zeng Y, Yan F, Ye J, Li Z
The international journal of biochemistry & cell biology 2024 Apr;169:106539
The international journal of biochemistry & cell biology 2024 Apr;169:106539
Identification of PKM2 as a pyroptosis-related key gene aggravates senile osteoporosis via the NLRP3/Caspase-1/GSDMD signaling pathway.
Li Z, Wang B, Wang R, Zhang Z, Xiong J, Wang X, Ma Y, Han L
The international journal of biochemistry & cell biology 2024 Apr;169:106537
The international journal of biochemistry & cell biology 2024 Apr;169:106537
SAMHD1 dysfunction induces IL-34 expression via NF-κB p65 in neuronal SH-SY5Y cells.
Zhang L, Wang W, Chen T, Cui J, Li X, Liu A, Liu R, Fang L, Jiang J, Yang L, Wu D, Ying S
Molecular immunology 2024 Apr;168:1-9
Molecular immunology 2024 Apr;168:1-9
NOTUM plays a bidirectionally modulatory role in the odontoblastic differentiation of human stem cells from the apical papilla through the WNT/β-catenin signaling pathway.
Zhao Q, Ren H, Wang N, Yuan X, Zhao Y, Wen Q
Archives of oral biology 2024 Apr;160:105896
Archives of oral biology 2024 Apr;160:105896
Engineered platelet-based immune engager for tumor post-surgery treatment.
Chen M, Zhang J, Li H, Deng Y, Huang Y, Shen W, Zeng Y, Ci T
Biomaterials advances 2024 Apr;158:213796
Biomaterials advances 2024 Apr;158:213796
Phenolics and terpenoids with good anti-inflammatory activity from the fruits of Amomum villosum and the anti-inflammatory mechanism of active diterpene.
Xu Y, Sun D, Xiong L, Zhang Z, Li Y, Liu K, Li H, Chen L
Bioorganic chemistry 2024 Apr;145:107190
Bioorganic chemistry 2024 Apr;145:107190
5Z-7-Oxozaenol attenuates cuprizone-induced demyelination in mice through microglia polarization regulation.
Chen S, Liu S, Huang Y, Huang S, Zhang W, Xie H, Lu L
Brain and behavior 2024 Apr;14(4):e3487
Brain and behavior 2024 Apr;14(4):e3487
Engagement of N(6)-methyladenisine methylation of Gng4 mRNA in astrocyte dysfunction regulated by CircHECW2.
Bai Y, Chang D, Ren H, Ju M, Wang Y, Chen B, Li H, Liu X, Li D, Huo X, Guo X, Tong M, Tan Y, Yao H, Han B
Acta pharmaceutica Sinica. B 2024 Apr;14(4):1644-1660
Acta pharmaceutica Sinica. B 2024 Apr;14(4):1644-1660
Glutathione Depletion-Induced Versatile Nanomedicine for Potentiating the Ferroptosis to Overcome Solid Tumor Radioresistance and Enhance Immunotherapy.
Song H, Sun H, He N, Xu C, Du L, Ji K, Wang J, Zhang M, Gu Y, Wang Y, Liu Q
Advanced healthcare materials 2024 Apr;13(9):e2303412
Advanced healthcare materials 2024 Apr;13(9):e2303412
The m6A methyltransferase METTL5 promotes neutrophil extracellular trap network release to regulate hepatocellular carcinoma progression.
Wang Q, Huang Y, Zhu Y, Zhang W, Wang B, Du X, Dai Q, Zhang F, Fang Z
Cancer medicine 2024 Apr;13(7):e7165
Cancer medicine 2024 Apr;13(7):e7165
The RNA-binding protein RBMS3 inhibits the progression of colon cancer by regulating the stability of LIMS1 mRNA.
Li Y, Wang S, Li G, Gao C, Cui Z, Cong M, Hu J, Zhang M, Jin X, Sun H, Kong D
Cancer medicine 2024 Apr;13(7):e7129
Cancer medicine 2024 Apr;13(7):e7129
Shen-Shuai-II-Recipe inhibits tubular inflammation by PPARα-mediated fatty acid oxidation to attenuate fibroblast activation in fibrotic kidneys.
Wang M, Wang L, Zhou L, Xu Y, Wang C
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Apr;126:155450
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Apr;126:155450
Artesunate improves glucose and lipid metabolism in db/db mice by regulating the metabolic profile and the MAPK/PI3K/Akt signalling pathway.
Chen L, Wang J, Ren Y, Ma Y, Liu J, Jiang H, Liu C
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Apr;126:155382
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Apr;126:155382
Calorie restriction mimetic, resveratrol, attenuates hepatic ischemia and reperfusion injury through enhancing efferocytosis of macrophages via AMPK/STAT3/S1PR1 pathway.
Yao X, Liu Y, Mao M, Yang L, Zhan Q, Xiao J
The Journal of nutritional biochemistry 2024 Apr;126:109587
The Journal of nutritional biochemistry 2024 Apr;126:109587
Moderate replacement of fish oil with palmitic acid-stimulated mitochondrial fusion promotes β-oxidation by Mfn2 interacting with Cpt1α via its GTPase-domain.
Song YF, Wang LJ, Luo Z, Hogstrand C, Lai XH, Zheng FF
The Journal of nutritional biochemistry 2024 Apr;126:109559
The Journal of nutritional biochemistry 2024 Apr;126:109559
Excessive fluoride induces ovarian function impairment by regulating levels of ferroptosis in fluorosis women and ovarian granulosa cells.
Geng N, Dong S, Xie P, Zhang Y, Shi R, Chen C, Xu Z, Chen Q
Reproductive toxicology (Elmsford, N.Y.) 2024 Apr;125:108556
Reproductive toxicology (Elmsford, N.Y.) 2024 Apr;125:108556
CXCL4/CXCR3 axis regulates cardiac fibrosis by activating TGF-β1/Smad2/3 signaling in mouse viral myocarditis.
Wei J, Wang DF, Cui CC, Tan JJ, Peng MY, Lu HX
Immunity, inflammation and disease 2024 Apr;12(4):e1237
Immunity, inflammation and disease 2024 Apr;12(4):e1237
Beta-Cell Tipe1 Orchestrates Insulin Secretion and Cell Proliferation by Promoting Gαs/cAMP Signaling via USP5.
Ding L, Sun Y, Liang Y, Zhang J, Fu Z, Ren C, Li P, Liu W, Xiao R, Wang H, Zhang Z, Yue X, Li C, Wu Z, Feng Y, Liang X, Ma C, Gao L
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Apr;11(16):e2304940
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Apr;11(16):e2304940
RBMS1 Coordinates with the m(6)A Reader YTHDF1 to Promote NSCLC Metastasis through Stimulating S100P Translation.
Sun Y, Chen D, Sun S, Ren M, Zhou L, Chen C, Zhao J, Wei H, Zhao Q, Qi Y, Zhang J, Zhang G, Liu H, Yang Q, Liu Q, Wang Y, Zhang W
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Apr;11(15):e2307122
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Apr;11(15):e2307122
A Nucleic Acid-Based LYTAC Plus Platform to Simultaneously Mediate Disease-Driven Protein Downregulation.
Huang Y, Zhou X, Zhang Y, Xie M, Wang F, Qin J, Ye H, Zhang H, Zhang C, Hong J
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Apr;11(13):e2306248
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Apr;11(13):e2306248
The surface morphology of Atractylodes macrocephala polysaccharide and its inhibitory effect on PCV2 replication.
Qi C, Lv C, Jiang M, Zhao X, Gao Y, Wang Y, Zhang P, Liu J, Zhao X
Journal of the science of food and agriculture 2024 Apr;104(6):3624-3636
Journal of the science of food and agriculture 2024 Apr;104(6):3624-3636
Influence of Growth Differentiation Factor 15 on Intraocular Pressure in Mice.
Maddala R, Eldawy C, Ho LTY, Challa P, Rao PV
Laboratory investigation; a journal of technical methods and pathology 2024 Apr;104(4):102025
Laboratory investigation; a journal of technical methods and pathology 2024 Apr;104(4):102025
TMAO promotes vascular endothelial cell pyroptosis via the LPEAT-mitophagy pathway.
Chen Y, Yuan C, Qin W, Yu B, Wei D, Wu P
Biochemical and biophysical research communications 2024 Apr 9;703:149667
Biochemical and biophysical research communications 2024 Apr 9;703:149667
Bile acids modified by the intestinal microbiota promote colorectal cancer growth by suppressing CD8(+) T cell effector functions.
Cong J, Liu P, Han Z, Ying W, Li C, Yang Y, Wang S, Yang J, Cao F, Shen J, Zeng Y, Bai Y, Zhou C, Ye L, Zhou R, Guo C, Cang C, Kasper DL, Song X, Dai L, Sun L, Pan W, Zhu S
Immunity 2024 Apr 9;57(4):876-889.e11
Immunity 2024 Apr 9;57(4):876-889.e11
GLUT3-mediated cigarette smoke-induced epithelial-mesenchymal transition in chronic obstructive pulmonary disease through the NF-kB/ZEB1 pathway.
Ding Y, Wang Z, Zhang Z, You R, Wu Y, Bian T
Respiratory research 2024 Apr 9;25(1):158
Respiratory research 2024 Apr 9;25(1):158
A study on the significance of serine hydroxymethyl transferase expression and its role in bladder cancer.
Su SW, Chen X, Wang G, Li P, Yang TX, Fang KW, Wu J, Li JM
Scientific reports 2024 Apr 9;14(1):8324
Scientific reports 2024 Apr 9;14(1):8324
G6PD maintains the VSMC synthetic phenotype and accelerates vascular neointimal hyperplasia by inhibiting the VDAC1-Bax-mediated mitochondrial apoptosis pathway.
Zhang T, Cao RJ, Niu JL, Chen ZH, Mu SQ, Cao T, Pang JX, Dong LH
Cellular & molecular biology letters 2024 Apr 8;29(1):47
Cellular & molecular biology letters 2024 Apr 8;29(1):47
STING inhibition suppresses microglia-mediated synapses engulfment and alleviates motor functional deficits after stroke.
Wu C, Zhang S, Sun H, Li A, Hou F, Qi L, Liao H
Journal of neuroinflammation 2024 Apr 8;21(1):86
Journal of neuroinflammation 2024 Apr 8;21(1):86
Curcumin regulates autophagy through SIRT3-SOD2-ROS signaling pathway to improve quadriceps femoris muscle atrophy in KOA rat model.
Ye H, Long Y, Yang JM, Wu YL, Dong LY, Zhong YB, Luo Y, Wang MY
Scientific reports 2024 Apr 8;14(1):8176
Scientific reports 2024 Apr 8;14(1):8176
Type III interferon inhibits bladder cancer progression by reprogramming macrophage-mediated phagocytosis and orchestrating effective immune responses.
Wang B, Zhou B, Chen J, Sun X, Yang W, Yang T, Yu H, Chen P, Chen K, Huang X, Fan X, He W, Huang J, Lin T
Journal for immunotherapy of cancer 2024 Apr 8;12(4)
Journal for immunotherapy of cancer 2024 Apr 8;12(4)
Klotho exerts protection in chronic kidney disease associated with regulating inflammatory response and lipid metabolism.
Liu J, Wang H, Liu Q, Long S, Wu Y, Wang N, Lin W, Chen G, Lin M, Wen J
Cell & bioscience 2024 Apr 7;14(1):46
Cell & bioscience 2024 Apr 7;14(1):46
Altered TFEB subcellular localization in nigral neurons of subjects with incidental, sporadic and GBA-related Lewy body diseases.
Moors TE, Morella ML, Bertran-Cobo C, Geut H, Udayar V, Timmermans-Huisman E, Ingrassia AMT, Brevé JJP, Bol JGJM, Bonifati V, Jagasia R, van de Berg WDJ
Acta neuropathologica 2024 Apr 6;147(1):67
Acta neuropathologica 2024 Apr 6;147(1):67
Irisin alters D-galactose-induced apoptosis by increasing caveolin-1 expression in C2C12 myoblasts and skeletal muscle fibroblasts.
Wu Y, Wu Y, Yu J, Zhang Y, Dai X, Chen J, Sun Y, Yang Y, Zhao K, Xiao Q
Molecular and cellular biochemistry 2024 Apr 6;
Molecular and cellular biochemistry 2024 Apr 6;
Licochalcone A induces mitochondria-dependent apoptosis and interacts with venetoclax in acute myeloid leukemia.
Li Y, Zhao M, Lin Y, Jiang X, Jin L, Ye P, Lu Y, Pei R, Jiang L
European journal of pharmacology 2024 Apr 5;968:176418
European journal of pharmacology 2024 Apr 5;968:176418
Zinc remodels mitochondrial network through SIRT3/Mfn2-dependent mitochondrial transfer in ameliorating spinal cord injury.
Guo H, Chen LQ, Zou ZR, Cheng S, Hu Y, Mao L, Tian H, Mei XF
European journal of pharmacology 2024 Apr 5;968:176368
European journal of pharmacology 2024 Apr 5;968:176368
Circulating tumor cells shielded with extracellular vesicle-derived CD45 evade T cell attack to enable metastasis.
Yang C, Wang X, To KKW, Cui C, Luo M, Wu S, Huang L, Fu K, Pan C, Liu Z, Fan T, Yang C, Wang F, Fu L
Signal transduction and targeted therapy 2024 Apr 5;9(1):84
Signal transduction and targeted therapy 2024 Apr 5;9(1):84
Mechanism of Smilax china L. in the treatment of intrauterine adhesions based on network pharmacology, molecular docking and experimental validation.
Shi T, Hou C, Duan Y, Li Y, Liu W, Huang P, Zhou Y, Yu S, Song L
BMC complementary medicine and therapies 2024 Apr 5;24(1):150
BMC complementary medicine and therapies 2024 Apr 5;24(1):150
Disrupted de novo pyrimidine biosynthesis impairs adult hippocampal neurogenesis and cognition in pyridoxine-dependent epilepsy.
Yan J, Wu J, Xu M, Wang M, Guo W
Science advances 2024 Apr 5;10(14):eadl2764
Science advances 2024 Apr 5;10(14):eadl2764
The mechanisms of MicroRNA 21 in premature ovarian insufficiency mice with mesenchymal stem cells transplantation : The involved molecular and immunological mechanisms.
Yin N, Luo C, Wei L, Yang G, Bo L, Mao C
Journal of ovarian research 2024 Apr 4;17(1):75
Journal of ovarian research 2024 Apr 4;17(1):75
Activating SRC/MAPK signaling via 5-HT1A receptor contributes to the effect of vilazodone on improving thrombocytopenia.
Zhou L, Ni C, Liao R, Tang X, Yi T, Ran M, Huang M, Liao R, Zhou X, Qin D, Wang L, Huang F, Xie X, Wan Y, Luo J, Wang Y, Wu J
eLife 2024 Apr 4;13
eLife 2024 Apr 4;13
Detailed phenotyping of Tbr1-2A-CreER knock-in mice demonstrates significant impacts on TBR1 protein levels and axon development.
Co M, O'Brien GK, Wright KM, O'Roak BJ
bioRxiv : the preprint server for biology 2024 Apr 4;
bioRxiv : the preprint server for biology 2024 Apr 4;
The c-Abl-RACK1-FAK signaling axis promotes renal fibrosis in mice through regulating fibroblast-myofibroblast transition.
Bao Q, Wang A, Hong W, Wang Y, Li B, He L, Yuan X, Ma G
Cell communication and signaling : CCS 2024 Apr 30;22(1):247
Cell communication and signaling : CCS 2024 Apr 30;22(1):247
Glutamine Promotes Porcine Intestinal Epithelial Cell Proliferation through the Wnt/β-Catenin Pathway.
Fang YX, Lu EQ, Cheng YJ, Xu E, Zhu M, Chen X
Journal of agricultural and food chemistry 2024 Apr 3;72(13):7155-7166
Journal of agricultural and food chemistry 2024 Apr 3;72(13):7155-7166
MATN2 overexpression suppresses tumor growth in ovarian cancer via PTEN/PI3K/AKT pathway.
Liu J, Zhang J, Zhang Y, Yang B, Liu H, Chen Y
Functional & integrative genomics 2024 Apr 3;24(2):71
Functional & integrative genomics 2024 Apr 3;24(2):71
Map-1a regulates Sertoli cell BTB dynamics through the cytoskeletal organization of microtubule and F-actin.
Wang L, Yan M, Bu T, Wu X, Li L, Silvestrini B, Sun F, Cheng CY, Chen H
Reproductive biology and endocrinology : RB&E 2024 Apr 3;22(1):36
Reproductive biology and endocrinology : RB&E 2024 Apr 3;22(1):36
Shank3 deficiency elicits autistic-like behaviors by activating p38α in hypothalamic AgRP neurons.
Wu S, Wang J, Zhang Z, Jin X, Xu Y, Si Y, Liang Y, Ge Y, Zhan H, Peng L, Bi W, Luo D, Li M, Meng B, Guan Q, Zhao J, Gao L, He Z
Molecular autism 2024 Apr 3;15(1):14
Molecular autism 2024 Apr 3;15(1):14
SorCS2 is involved in promoting periodontitis-induced depression-like behaviour in mice.
Li Y, Yang Y, Guan X, Liu Z, Pan L, Wang Y, Jia X, Yang J, Hou T
Oral diseases 2024 Apr 3;
Oral diseases 2024 Apr 3;
Contributions of the Dachsous intracellular domain to Dachsous-Fat signaling.
Tripathi BK, Irvine KD
bioRxiv : the preprint server for biology 2024 Apr 3;
bioRxiv : the preprint server for biology 2024 Apr 3;
Pretreatment with interleukin-15 attenuates inflammation and apoptosis by inhibiting NF-κB signaling in sepsis-induced myocardial dysfunction.
He C, Yu Y, Wang F, Li W, Ni H, Xiang M
European journal of histochemistry : EJH 2024 Apr 29;68(2)
European journal of histochemistry : EJH 2024 Apr 29;68(2)
Mitophagy Regulates the Circadian Rhythms by Degrading NR1D1 in Simulated Microgravity and Isolation Environments.
Zhou S, Li X, Liang F, Ji G, Lv K, Yuan Y, Zhao Y, Yan N, Zhang C, Cai S, Zhang S, Liu X, Song B, Qu L
International journal of molecular sciences 2024 Apr 29;25(9)
International journal of molecular sciences 2024 Apr 29;25(9)
Deubiquitination of CDC6 by OTUD6A promotes tumour progression and chemoresistance.
Cui J, Liu X, Shang Q, Sun S, Chen S, Dong J, Zhu Y, Liu L, Xia Y, Wang Y, Xiang L, Fan B, Zhan J, Zhou Y, Chen P, Zhao R, Liu X, Xing N, Wu D, Shi B, Zou Y
Molecular cancer 2024 Apr 29;23(1):86
Molecular cancer 2024 Apr 29;23(1):86
Therapeutic efficacy of a novel self-assembled immunostimulatory siRNA combining apoptosis promotion with RIG-I activation in gliomas.
Chen J, Liu Z, Fang H, Su Q, Fan Y, Song L, He S
Journal of translational medicine 2024 Apr 29;22(1):395
Journal of translational medicine 2024 Apr 29;22(1):395
The Planar Cell Polarity Protein Fat1 in Sertoli Cell Function.
Bu T, Wang L, Wu X, Gao S, Li X, Yun D, Yang X, Li L, Cheng CY, Sun F
Endocrinology 2024 Apr 29;165(6)
Endocrinology 2024 Apr 29;165(6)
Targeting PARP14 with lomitapide suppresses drug resistance through the activation of DRP1-induced mitophagy in multiple myeloma.
Zhang H, Wang H, Hu Y, Gao Y, Chen J, Meng Y, Qiu Y, Hu R, Liao P, Li M, He Y, Liang Z, Xie X, Li Y
Cancer letters 2024 Apr 28;588:216802
Cancer letters 2024 Apr 28;588:216802
Sokotrasterol Sulfate Suppresses IFN-γ-Induced PD-L1 Expression by Inhibiting JAK Activity.
Wang X, Xu W, Wang Z, Yu Q, Yuan L, Liu Y, Sang J, Li W, Zhu S, Jiang W, Li Z, Zhang W, Dang Y
Journal of natural products 2024 Apr 26;87(4):713-721
Journal of natural products 2024 Apr 26;87(4):713-721
DEC1 is involved in circadian rhythm disruption-exacerbated pulmonary fibrosis.
Chen SJ, Yu F, Feng X, Li Q, Jiang YH, Zhao LQ, Cheng PP, Wang M, Song LJ, Liang LM, He XL, Xiong L, Xiang F, Wang X, Ye H, Ma WL
Cell communication and signaling : CCS 2024 Apr 26;22(1):245
Cell communication and signaling : CCS 2024 Apr 26;22(1):245
Expression and functional significance of phosphoenolpyruvate carboxykinase 1 in uveal melanoma.
Bi HE, Zhang J, Yao Y, Wang S, Yao J, Shao Z, Jiang Q
Cell death discovery 2024 Apr 26;10(1):196
Cell death discovery 2024 Apr 26;10(1):196
Iridium(III)-Based PD-L1 Agonist Regulates p62 and ATF3 for Enhanced Cancer Immunotherapy.
Deng D, Wang M, Su Y, Fang H, Chen Y, Su Z
Journal of medicinal chemistry 2024 Apr 25;67(8):6810-6821
Journal of medicinal chemistry 2024 Apr 25;67(8):6810-6821
Unlocking the power of immunotherapy: Combinatorial delivery of plasmid IL-15 and gemcitabine to synergistically remodeling the tumor microenvironment.
Liu J, Han Y, Zhao M, Wang L, Hu H, Chen D
International journal of pharmaceutics 2024 Apr 25;655:124027
International journal of pharmaceutics 2024 Apr 25;655:124027
Rosamultin ameliorates radiation injury via promoting DNA injury repair and suppressing oxidative stress in vitro and in vivo.
Liu N, Niu M, Luo S, Lv L, Quan X, Wang C, Meng Z, Yuan J, Xu Q, Liu Y
Chemico-biological interactions 2024 Apr 25;393:110938
Chemico-biological interactions 2024 Apr 25;393:110938
Positive selection CRISPR screens reveal a druggable pocket in an oligosaccharyltransferase required for inflammatory signaling to NF-κB.
Lampson BL, Ramίrez AS, Baro M, He L, Hegde M, Koduri V, Pfaff JL, Hanna RE, Kowal J, Shirole NH, He Y, Doench JG, Contessa JN, Locher KP, Kaelin WG Jr
Cell 2024 Apr 25;187(9):2209-2223.e16
Cell 2024 Apr 25;187(9):2209-2223.e16
Promoter hypomethylated PDZK1 acts as a tumorigenic gene in glioma by interacting with AKT1.
Ren X, Deng D, Xiang S, Feng J
Aging 2024 Apr 25;16(8):7174-7187
Aging 2024 Apr 25;16(8):7174-7187
Distinct functions for the paralogous RBM41 and U11/U12-65K proteins in the minor spliceosome.
Norppa AJ, Chowdhury I, van Rooijen LE, Ravantti JJ, Snel B, Varjosalo M, Frilander MJ
Nucleic acids research 2024 Apr 24;52(7):4037-4052
Nucleic acids research 2024 Apr 24;52(7):4037-4052
Diterpenoid tanshinones inhibit gastric cancer angiogenesis through the PI3K/Akt/mTOR signaling pathway.
Yu JR, Liu YY, Gao YY, Qian LH, Qiu JL, Wang PP, Zhang GJ
Journal of ethnopharmacology 2024 Apr 24;324:117791
Journal of ethnopharmacology 2024 Apr 24;324:117791
Identification of different myofiber types in pigs muscles and construction of regulatory networks.
Li C, Wang Y, Sun X, Yang J, Ren Y, Jia J, Yang G, Liao M, Jin J, Shi X
BMC genomics 2024 Apr 24;25(1):400
BMC genomics 2024 Apr 24;25(1):400
OTUD5 promotes the growth of hepatocellular carcinoma by deubiquitinating and stabilizing SLC38A1.
Yang Y, Jia S, Zhu N, Xiao X, Ma Y, Tu K, Guo Y, Xu Q
Biology direct 2024 Apr 24;19(1):31
Biology direct 2024 Apr 24;19(1):31
Exploring the Potential Mechanisms of Guanxinshutong Capsules in Treating Pathological Cardiac Hypertrophy based on Network Pharmacology, Computer-Aided Drug Design, and Animal Experiments.
Liu Y, Li Q, Shao C, She Y, Zhou H, Guo Y, An H, Wang T, Yang J, Wan H
ACS omega 2024 Apr 23;9(16):18083-18098
ACS omega 2024 Apr 23;9(16):18083-18098
TMC7 functions as a suppressor of Piezo2 in primary sensory neurons blunting peripheral mechanotransduction.
Zhang X, Shao J, Wang C, Liu C, Hao H, Li X, An Y, He J, Zhao W, Zhao Y, Kong Y, Jia Z, Wan S, Yuan Y, Zhang H, Zhang H, Du X
Cell reports 2024 Apr 23;43(4):114014
Cell reports 2024 Apr 23;43(4):114014
Endocytic activation and exosomal secretion of matriptase stimulate the second wave of EGF signaling to promote skin and breast cancer invasion.
Ye F, Yuan Z, Tang Y, Li J, Liu X, Sun X, Chen S, Ye X, Zeng Z, Zhang XK, Zhou H
Cell reports 2024 Apr 23;43(4):114002
Cell reports 2024 Apr 23;43(4):114002
Pharmacodynamic and Toxicity Studies of 6-Isopropyldithio-2'-guanosine Analogs in Acute T-Lymphoblastic Leukemia.
Song T, Yu Z, Shen Q, Xu Y, Hu H, Liu J, Zeng K, Lei J, Yu L
Cancers 2024 Apr 23;16(9)
Cancers 2024 Apr 23;16(9)
CMYC-initiated HNF1A-AS1 overexpression maintains the stemness of gastric cancer cells.
Zhao R, Guo X, Zhang G, Liu S, Ma R, Wang M, Chen S, Zhu W, Liu Y, Gao P, Liu H
Cell death & disease 2024 Apr 23;15(4):288
Cell death & disease 2024 Apr 23;15(4):288
Differences between human male and female neutrophils in mRNA, translation efficiency, protein, and phosphoprotein profiles.
Pilling D, Consalvo KM, Kirolos SA, Gomer RH
Research square 2024 Apr 23;
Research square 2024 Apr 23;
A Proximity Complementation Assay to Identify Small Molecules That Enhance the Traffic of ABCA4 Misfolding Variants.
Piccolo D, Zarouchlioti C, Bellingham J, Guarascio R, Ziaka K, Molday RS, Cheetham ME
International journal of molecular sciences 2024 Apr 20;25(8)
International journal of molecular sciences 2024 Apr 20;25(8)
The role of FPR2-mediated ferroptosis in formyl peptide-induced acute lung injury against endothelial barrier damage and protective effect of the mitochondria-derived peptide MOTS-c.
Wen Z, Fan J, Zhan F, Li X, Li B, Lu P, Yao X, Shen Z, Liu Z, Wang C, Li X, Jin W, Zhang X, Qi Y, Wang X, Song M
International immunopharmacology 2024 Apr 20;131:111911
International immunopharmacology 2024 Apr 20;131:111911
Physalin H ameliorates LPS-induced acute lung injury via KEAP1/NRF2 axis.
Cai Y, Zhu J, Zhu L, Hong L, Zhang J, Kong L, Chen C, Luo J
International immunopharmacology 2024 Apr 20;131:111789
International immunopharmacology 2024 Apr 20;131:111789
SERPINB5 promotes colorectal cancer invasion and migration by promoting EMT and angiogenesis via the TNF-α/NF-κB pathway.
Liu BX, Xie Y, Zhang J, Zeng S, Li J, Tao Q, Yang J, Chen Y, Zeng C
International immunopharmacology 2024 Apr 20;131:111759
International immunopharmacology 2024 Apr 20;131:111759
Incorporating Network Pharmacology and Experimental Validation to Identify Bioactive Compounds and Potential Mechanisms of Digitalis in Treating Anaplastic Thyroid Cancer.
Zhu L, Liang R, Guo Y, Cai Y, Song F, Hu Y, Liu Y, Ge M, Zheng G
ACS omega 2024 Apr 2;9(13):15590-15602
ACS omega 2024 Apr 2;9(13):15590-15602
Unveiling the therapeutic potential of Dl-3-n-butylphthalide in NTG-induced migraine mouse: activating the Nrf2 pathway to alleviate oxidative stress and neuroinflammation.
Liu Y, Gong Z, Zhai D, Yang C, Lu G, Wang S, Xiao S, Li C, Chen L, Lin X, Zhang S, Yu S, Dong Z
The journal of headache and pain 2024 Apr 2;25(1):50
The journal of headache and pain 2024 Apr 2;25(1):50
Irisin attenuates type 1 diabetic cardiomyopathy by anti-ferroptosis via SIRT1-mediated deacetylation of p53.
Tang YJ, Zhang Z, Yan T, Chen K, Xu GF, Xiong SQ, Wu DQ, Chen J, Jose PA, Zeng CY, Fu JJ
Cardiovascular diabetology 2024 Apr 2;23(1):116
Cardiovascular diabetology 2024 Apr 2;23(1):116
EP300-ZNF384 transactivates IL3RA to promote the progression of B-cell acute lymphoblastic leukemia.
Hou Z, Ren Y, Zhang X, Huang D, Yan F, Sun W, Zhang W, Zhang Q, Fu X, Lang Z, Chu C, Zou B, Gao B, Jin B, Kang Z, Liu Q, Yan J
Cell communication and signaling : CCS 2024 Apr 2;22(1):211
Cell communication and signaling : CCS 2024 Apr 2;22(1):211
6-Gingerol attenuates hepatic ischemia/reperfusion injury through regulating MKP5-mediated P38/JNK pathway.
Yu Q, Li J, Cui M, Mei C, He Q, Du X
Scientific reports 2024 Apr 2;14(1):7747
Scientific reports 2024 Apr 2;14(1):7747
TRIM56-mediated production of type I interferon inhibits intracellular replication of Rickettsia rickettsii.
Cheng R, Zhou C, Zhao M, Zhang S, Wan W, Yu Y, Wen B, Jiao J, Xiong X, Xu Q, OuYang X
Microbiology spectrum 2024 Apr 2;12(4):e0369523
Microbiology spectrum 2024 Apr 2;12(4):e0369523
Inhibition of SARS-CoV-2 replication by a ssDNA aptamer targeting the nucleocapsid protein.
Huang Y, Huang C, Chen J, Chen S, Li B, Li J, Jin Z, Zhang Q, Pan P, Du W, Liu L, Liu Z
Microbiology spectrum 2024 Apr 2;12(4):e0341023
Microbiology spectrum 2024 Apr 2;12(4):e0341023
ACSL4 accelerates osteosarcoma progression via modulating TGF-β/Smad2 signaling pathway.
Li X, Chen Q, Zhao D, Tan J, Liao R, Gu Y, Zhu J, Zhang H, Xie J, Chen L
Molecular and cellular biochemistry 2024 Apr 2;
Molecular and cellular biochemistry 2024 Apr 2;
TDP-43 deficiency in suprachiasmatic nucleus perturbs rhythmicity of neuroactivity in prefrontal cortex.
Zhang H, Chen C, Zhang EE, Huang X
iScience 2024 Apr 19;27(4):109522
iScience 2024 Apr 19;27(4):109522
Non-random spatial organization of telomeres varies during the cell cycle and requires LAP2 and BAF.
Keller D, Stinus S, Umlauf D, Gourbeyre E, Biot E, Olivier N, Mahou P, Beaurepaire E, Andrey P, Crabbe L
iScience 2024 Apr 19;27(4):109343
iScience 2024 Apr 19;27(4):109343
AP39 through AMPK-ULK1-FUNDC1 pathway regulates mitophagy, inhibits pyroptosis, and improves doxorubicin-induced myocardial fibrosis.
Zhao J, Yang T, Yi J, Hu H, Lai Q, Nie L, Liu M, Chu C, Yang J
iScience 2024 Apr 19;27(4):109321
iScience 2024 Apr 19;27(4):109321
Missing WD40 Repeats in ATG16L1 Delays Canonical Autophagy and Inhibits Noncanonical Autophagy.
Tang J, Fang D, Zhong J, Li M
International journal of molecular sciences 2024 Apr 19;25(8)
International journal of molecular sciences 2024 Apr 19;25(8)
Acupuncture Extended the Thrombolysis Window by Suppressing Blood-Brain Barrier Disruption and Regulating Autophagy-Apoptosis Balance after Ischemic Stroke.
Zhang Z, Lu T, Li S, Zhao R, Li H, Zhang X, Li Y, Xia Y, Ni G
Brain sciences 2024 Apr 19;14(4)
Brain sciences 2024 Apr 19;14(4)
Lung cancer cell-intrinsic IL-15 promotes cell migration and sensitizes murine lung tumors to anti-PD-L1 therapy.
Hu S, Meng K, Wang T, Qu R, Wang B, Xi Y, Yu T, Yuan Z, Cai Z, Tian Y, Zeng C, Wang X, Zou W, Fu X, Li L
Biomarker research 2024 Apr 19;12(1):40
Biomarker research 2024 Apr 19;12(1):40
RIPK3 deficiency blocks R-2-hydroxyglutarate-induced necroptosis in IDH-mutated AML cells.
Zhu S, Luo Y, Li K, Mei C, Wang Y, Jiang L, Wang W, Zhang Q, Yang W, Lang W, Zhou X, Wang L, Ren Y, Ma L, Ye L, Huang X, Chen J, Sun J, Tong H
Science advances 2024 Apr 19;10(16):eadi1782
Science advances 2024 Apr 19;10(16):eadi1782
Neutrophil Extracellular Traps Regulate Surgical Brain Injury by Activating the cGAS-STING Pathway.
Li B, Xu L, Wang Z, Shi Q, Cui Y, Fan W, Wu Q, Tong X, Yan H
Cellular and molecular neurobiology 2024 Apr 18;44(1):36
Cellular and molecular neurobiology 2024 Apr 18;44(1):36
OPA1 mutation affects autophagy and triggers senescence in autosomal dominant optic atrophy plus fibroblasts.
Zanfardino P, Amati A, Doccini S, Cox SN, Tullo A, Longo G, D'Erchia A, Picardi E, Nesti C, Santorelli FM, Petruzzella V
Human molecular genetics 2024 Apr 18;33(9):768-786
Human molecular genetics 2024 Apr 18;33(9):768-786
Modulation of peroxisomal import by the PEX13 SH3 domain and a proximal FxxxF binding motif.
Gaussmann S, Peschel R, Ott J, Zak KM, Sastre J, Delhommel F, Popowicz GM, Boekhoven J, Schliebs W, Erdmann R, Sattler M
Nature communications 2024 Apr 18;15(1):3317
Nature communications 2024 Apr 18;15(1):3317
Bioactive 3D Electrohydrodynamic Printed Lattice Architectures Augment Tenogenesis of Tendon Stem/Progenitor Cells.
Wang L, Shi Y, Qiu Z, Dang J, Sun L, Qu X, He J, Fan H
ACS applied materials & interfaces 2024 Apr 17;16(15):18574-18590
ACS applied materials & interfaces 2024 Apr 17;16(15):18574-18590
Hepatitis E virus ORF3 protein hijacking thioredoxin domain-containing protein 5 (TXNDC5) for its stability to promote viral particle release.
Sheng Y, Deng Y, Li X, Ji P, Sun X, Liu B, Zhu J, Zhao J, Nan Y, Zhou E-M, Hiscox JA, Stewart JP, Sun Y, Zhao Q
Journal of virology 2024 Apr 16;98(4):e0164923
Journal of virology 2024 Apr 16;98(4):e0164923
Lipidomics reveals the significance and mechanism of the cellular ceramide metabolism for rotavirus replication.
Tao R, Cheng X, Gu L, Zhou J, Zhu X, Zhang X, Guo R, Wang W, Li B
Journal of virology 2024 Apr 16;98(4):e0006424
Journal of virology 2024 Apr 16;98(4):e0006424
TSHR signaling promotes hippocampal dependent memory formation through modulating Wnt5a/β-catenin mediated neurogenesis.
Li Y, Luan S, Ruan C, Li W, Zhang X, Ran Z, Bi W, Tong Y, Gao L, Zhao J, Li Y, He Z
Biochemical and biophysical research communications 2024 Apr 16;704:149723
Biochemical and biophysical research communications 2024 Apr 16;704:149723
Identification of a novel FOXO3 agonist that protects against alcohol induced liver injury.
Peng J, Liang G, Li Y, Mao S, Zhang C, Wang Y, Li Z
Biochemical and biophysical research communications 2024 Apr 16;704:149690
Biochemical and biophysical research communications 2024 Apr 16;704:149690
Inhibition of autophagy-related protein 7 enhances anti-tumor immune response and improves efficacy of immune checkpoint blockade in microsatellite instability colorectal cancer.
Zhang W, Chen L, Liu J, Chen B, Shi H, Chen H, Qi H, Wu Z, Mao X, Wang X, Huang Y, Li J, Yu Z, Zhong M, Wang T, Li Q
Journal of experimental & clinical cancer research : CR 2024 Apr 16;43(1):114
Journal of experimental & clinical cancer research : CR 2024 Apr 16;43(1):114
Identification and validation of a lactate metabolism-related six-gene prognostic signature in intrahepatic cholangiocarcinoma.
Sang C, Yan L, Lin J, Lin Y, Gao Q, Shen X
Journal of cancer research and clinical oncology 2024 Apr 16;150(4):199
Journal of cancer research and clinical oncology 2024 Apr 16;150(4):199
Construction and validation of a folate metabolism-related gene signature for predicting prognosis in HNSCC.
Wang L, He Y, Bai Y, Zhang S, Pang B, Chen A, Wu X
Journal of cancer research and clinical oncology 2024 Apr 16;150(4):198
Journal of cancer research and clinical oncology 2024 Apr 16;150(4):198
KDM5C-Mediated Recruitment of BRD4 to Chromatin Regulates Enhancer Activation and BET Inhibitor Sensitivity.
Qiang Y, Fan J, Xie C, Yan L, Song X, Zhang N, Lin Y, Xiong J, Zhang W, Liu Y, Wei L, Li Y, Chen S, Liang K, Li F
Cancer research 2024 Apr 15;84(8):1252-1269
Cancer research 2024 Apr 15;84(8):1252-1269
hsa_circ_0007919 promotes pancreatic cancer metastasis by modulating Sp1-mediated THBS1 transcription.
Ma X, Xu L, Gong S, Wu N, Guo J, Feng X, Zhao M, Qiu S, Sun M, Zhang C, Zhang X, Ren Z, Zhang P
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Apr 15;38(7):e23591
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Apr 15;38(7):e23591
PRMT4 interacts with NCOA4 to inhibit ferritinophagy in cisplatin-induced acute kidney injury.
Zhou L, Deng Z, Wang Y, Zhang H, Yan S, Kanwar YS, Wang Y, Dai Y, Deng F
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Apr 15;38(7):e23584
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Apr 15;38(7):e23584
TDCPP and TiO(2) NPs aggregates synergistically induce SH-SY5Y cell neurotoxicity by excessive mitochondrial fission and mitophagy inhibition.
Wang L, Wang B, Zhang X, Yang Z, Zhang X, Gong H, Song Y, Zhang K, Sun M
Environmental pollution (Barking, Essex : 1987) 2024 Apr 15;347:123740
Environmental pollution (Barking, Essex : 1987) 2024 Apr 15;347:123740
Mesenchymal Stem Cells-Derived Exosomes Alleviate Acute Lung Injury by Inhibiting Alveolar Macrophage Pyroptosis.
Liu P, Yang S, Shao X, Li C, Wang Z, Dai H, Wang C
Stem cells translational medicine 2024 Apr 15;13(4):371-386
Stem cells translational medicine 2024 Apr 15;13(4):371-386
AURKA knockdown inhibits esophageal squamous cell carcinoma progression through ferroptosis.
Mi Y, Chen L, Wang C, Miao Y, Song C, Su J, Wang L
Heliyon 2024 Apr 15;10(7):e28365
Heliyon 2024 Apr 15;10(7):e28365
Butyrate attenuates the stemness of lung cancer cells through lysosome Fe(2+)- and SLC7A11-mediated ferroptosis.
Bi R, Jiang L, Hu R, Wen B, Jiang Z, Liu H, Mei J
Heliyon 2024 Apr 15;10(7):e28093
Heliyon 2024 Apr 15;10(7):e28093
Incorporating machine learning and PPI networks to identify mitochondrial fission-related immune markers in abdominal aortic aneurysms.
Liu YJ, Li R, Xiao D, Yang C, Li YL, Chen JL, Wang Z, Zhao XG, Shan ZG
Heliyon 2024 Apr 15;10(7):e27989
Heliyon 2024 Apr 15;10(7):e27989
Endothelin-1-mediated Brainstem Glial Activation Produces Asthmatic Airway Vagal Hypertonia Via Enhanced ATP-P2X4 Receptor Signaling in Sprague-Dawley Rats.
Lin Y, Liu T, Chen H, Zeng M, Hu S, Yu X, Chen Y, Xia C, Wang J, Wang J
Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology 2024 Apr 13;19(1):13
Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology 2024 Apr 13;19(1):13
FBXL8 inhibits post-myocardial infarction cardiac fibrosis by targeting Snail1 for ubiquitin-proteasome degradation.
Li Y, Zuo C, Wu X, Ding Y, Wei Y, Chen S, Lu X, Xu J, Liu S, Zhou G, Cai L
Cell death & disease 2024 Apr 13;15(4):263
Cell death & disease 2024 Apr 13;15(4):263
KYNA Ameliorates Glutamate Toxicity of HAND by Enhancing Glutamate Uptake in A2 Astrocytes.
Chen J, Zou J, Huang P, Gao X, Lun J, Li Y, Gong Z, Cao H
International journal of molecular sciences 2024 Apr 12;25(8)
International journal of molecular sciences 2024 Apr 12;25(8)
The Suppression of the Epithelial to Mesenchymal Transition in Prostate Cancer through the Targeting of MYO6 Using MiR-145-5p.
Armstrong L, Willoughby CE, McKenna DJ
International journal of molecular sciences 2024 Apr 12;25(8)
International journal of molecular sciences 2024 Apr 12;25(8)
Garlic oil supplementation blocks inflammatory pyroptosis-related acute lung injury by suppressing the NF-κB/NLRP3 signaling pathway via H(2)S generation.
Dilxat T, Shi Q, Chen X, Liu X
Aging 2024 Apr 12;16(7):6521-6536
Aging 2024 Apr 12;16(7):6521-6536
Developing nucleoside tailoring strategies against SARS-CoV-2 via ribonuclease targeting chimera.
Min Y, Xiong W, Shen W, Liu X, Qi Q, Zhang Y, Fan R, Fu F, Xue H, Yang H, Sun X, Ning Y, Tian T, Zhou X
Science advances 2024 Apr 12;10(15):eadl4393
Science advances 2024 Apr 12;10(15):eadl4393
CARMA3 Drives NF-κB Activation and Promotes Intervertebral Disc Degeneration: Involvement of CARMA3-BCL10-MALT1 Signalosome.
Liu Y, Zhang G, Wu J, Meng Y, Hu J, Fu H, Yang D
Inflammation 2024 Apr 12;
Inflammation 2024 Apr 12;
The Long Noncoding RNA Gall Bladder Cancer-Associated Suppressor of Pyruvate Carboxylase Inhibits the Proliferation, Migration, and Invasion of Colorectal Cancer Cells and Induces Their Apoptosis.
Xie T, Guo J, Wang W
Biochemical genetics 2024 Apr 12;
Biochemical genetics 2024 Apr 12;
Structural basis for dimerization of a paramyxovirus polymerase complex.
Xie J, Ouizougun-Oubari M, Wang L, Zhai G, Wu D, Lin Z, Wang M, Ludeke B, Yan X, Nilsson T, Gao L, Huang X, Fearns R, Chen S
Nature communications 2024 Apr 11;15(1):3163
Nature communications 2024 Apr 11;15(1):3163
Palmitoylation alters LDHA activity and pancreatic cancer response to chemotherapy.
Chen L, Xing X, Zhu Y, Chen Y, Pei H, Song Q, Li J, Zhang P
Cancer letters 2024 Apr 10;587:216696
Cancer letters 2024 Apr 10;587:216696
Cascade-Catalyzed Nanogel for Amplifying Starvation Therapy by Nitric Oxide-Mediated Hypoxia Alleviation.
Wang W, Niu Y, Zhang N, Wan Y, Xiao Y, Zhao L, Zhao B, Chen W, Huang D
ACS applied materials & interfaces 2024 Apr 10;16(14):17313-17322
ACS applied materials & interfaces 2024 Apr 10;16(14):17313-17322
PRMT1 Sustains De Novo Fatty Acid Synthesis by Methylating PHGDH to Drive Chemoresistance in Triple-Negative Breast Cancer.
Yamamoto T, Hayashida T, Masugi Y, Oshikawa K, Hayakawa N, Itoh M, Nishime C, Suzuki M, Nagayama A, Kawai Y, Hishiki T, Matsuura T, Naito Y, Kubo A, Yamamoto A, Yoshioka Y, Kurahori T, Nagasaka M, Takizawa M, Takano N, Kawakami K, Sakamoto M, Wakui M, Yamamoto T, Kitagawa Y, Kabe Y, Horisawa K, Suzuki A, Matsumoto M, Suematsu M
Cancer research 2024 Apr 1;84(7):1065-1083
Cancer research 2024 Apr 1;84(7):1065-1083
Glutaminolysis regulates endometrial fibrosis in intrauterine adhesion via modulating mitochondrial function.
Chen P, Ye C, Huang Y, Xu B, Wu T, Dong Y, Jin Y, Zhao L, Hu C, Mao J, Wu R
Biological research 2024 Apr 1;57(1):13
Biological research 2024 Apr 1;57(1):13
KLF10/CBS increases the sensitivity of gastric carcinoma cells to methionine restriction by promoting sulfur transfer pathway.
Xin L, Liu ZY, Liu CX, Sheng J, Zhou Q, Yuan YW, Yue ZQ, Lu H, Gan JH
Experimental cell research 2024 Apr 1;437(1):114007
Experimental cell research 2024 Apr 1;437(1):114007
Spastin regulates anaphase chromosome separation distance and microtubule-containing nuclear tunnels.
Kelley ME, Carlini L, Kornakov N, Aher A, Khodjakov A, Kapoor TM
Molecular biology of the cell 2024 Apr 1;35(4):ar48
Molecular biology of the cell 2024 Apr 1;35(4):ar48
Human gestational diabetes mellitus-derived exosomes impair glucose homeostasis in pregnant mice and stimulate functional maturation of offspring-islets.
Zou L, Xu C, Wang L, Cao X, Jia X, Yang Z, Jiang G, Ji L
Life sciences 2024 Apr 1;342:122514
Life sciences 2024 Apr 1;342:122514
Sialylation on vesicular integrin β1 determined endocytic entry of small extracellular vesicles into recipient cells.
Lin M, Xu X, Zhou X, Feng H, Wang R, Yang Y, Li J, Fan N, Jiang Y, Li X, Guan F, Tan Z
Cellular & molecular biology letters 2024 Apr 1;29(1):46
Cellular & molecular biology letters 2024 Apr 1;29(1):46
Neonatal microglia transplantation at early stage but not late stage after traumatic brain injury shows protective effects in mice.
Chen M, Wang H, Chen P, Zhu G, Li S, Li Z, Liu X, Ye G, Chen W
Journal of neurophysiology 2024 Apr 1;131(4):598-606
Journal of neurophysiology 2024 Apr 1;131(4):598-606
Paracatalytic induction: Subverting specificity in hedgehog protein autoprocessing with small molecules.
Ciulla DA, Xu Z, Pezzullo JL, Dranchak P, Wang C, Giner JL, Inglese J, Callahan BP
Methods in enzymology 2023;685:1-41
Methods in enzymology 2023;685:1-41
Isolation and Cultivation of Vascular Smooth Muscle Cells from the Mouse Circle of Willis.
Chang W, Li Y, Liu F, Zang K, Zhang P, Qu S, Zhao J, Xue J
Journal of vascular research 2023;60(4):234-244
Journal of vascular research 2023;60(4):234-244
SERBP1 Promotes Stress Granule Clearance by Regulating 26S Proteasome Activity and G3BP1 Ubiquitination and Protects Male Germ Cells from Thermostimuli Damage.
Wang F, Wang L, Gan S, Feng S, Ouyang S, Wang X, Yuan S
Research (Washington, D.C.) 2023;6:0091
Research (Washington, D.C.) 2023;6:0091
Inhibition of LAMP3 mediates the protective effect of vitamin D against hypoxia/reoxygenation in trophoblast cells.
Tian X, Zheng L, Ma J, Xu Y, Zhang Y, Pi Y
Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 2023;56:e12816
Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 2023;56:e12816
Fucoidan alleviates the hepatorenal syndrome through inhibition organic solute transporter α/β to reduce bile acids reabsorption.
Zhao X, Yang T, Zhou J, Chen Y, Shen Q, Zhang J, Qiu Q
Current research in pharmacology and drug discovery 2023;5:100159
Current research in pharmacology and drug discovery 2023;5:100159
Rapamycin attenuates pyroptosis by suppressing mTOR phosphorylation and promoting autophagy in LPS-induced bronchopulmonary dysplasia.
Zhang F, Wang M, Li Z, Deng J, Fan Y, Gou Z, Zhou Y, Huang L, Lu L
Experimental lung research 2023;49(1):178-192
Experimental lung research 2023;49(1):178-192
Identification of PDK4 as Hub Gene for Diabetic Nephropathy Using Co-Expression Network Analysis.
Han Y, Jin L, Wang L, Wei L, Tu C
Kidney & blood pressure research 2023;48(1):522-534
Kidney & blood pressure research 2023;48(1):522-534
Functional enhancement of acute infracted heart by coinjection of autologous adipose-derived stem cells with matrigel.
Wang BZ, Wang MM, Li Y, Shao MH, Zhang D, Yan SQ, Ma X, Ma YT
Turkish journal of biology = Turk biyoloji dergisi 2023;47(3):170-185
Turkish journal of biology = Turk biyoloji dergisi 2023;47(3):170-185
ELK3 Targeting AEG1 Promotes Migration and Invasion of Ovarian Cancer Cells under Hypoxia.
Yu X, Du C, Cui Y, Jiang Y, Feng D
Biological & pharmaceutical bulletin 2023;46(7):883-892
Biological & pharmaceutical bulletin 2023;46(7):883-892
Tilianin Protects against Nonalcoholic Fatty Liver Disease in Early Obesity Mice.
Xu SM, Xu Y, Cheng XG, Yang LQ
Biological & pharmaceutical bulletin 2023;46(3):419-426
Biological & pharmaceutical bulletin 2023;46(3):419-426
LncRNA AK001796 promotes cell proliferation via acting as a ceRNA of miR-150 in hepatocellular carcinoma.
Xu R, He H, Wang Y, Peng Q, Mei K, Liu Y, Yang Q
Genetics and molecular biology 2023;46(2):e20220277
Genetics and molecular biology 2023;46(2):e20220277
GLIS Family Zinc Finger 3 Promotes Triple-Negative Breast Cancer Progression by Inducing Cell Proliferation, Migration and Invasion, and Activating the NF-κB Signaling Pathway.
Li C, Geng C
Biological & pharmaceutical bulletin 2023;46(2):209-218
Biological & pharmaceutical bulletin 2023;46(2):209-218
Tumor-Promoting Properties of TMEM9A in Breast Cancer Progression via Activating the Wnt/β-Catenin Signaling Pathway.
He J, Bu Y, Li X, Zhang X, Ma L
Biological & pharmaceutical bulletin 2023;46(1):74-85
Biological & pharmaceutical bulletin 2023;46(1):74-85
Penehyclidine Hydrochloride Protects Rat Cardiomyocytes from Ischemia- Reperfusion Injury by Platelet-derived Growth Factor-B.
Lu Y, Zi C, Zhang L, Cui B, Li L, Ma J
Combinatorial chemistry & high throughput screening 2023;26(6):1204-1213
Combinatorial chemistry & high throughput screening 2023;26(6):1204-1213
Featured interactome of homocysteine-inducible endoplasmic reticulum protein uncovers novel binding partners in response to ER stress.
Su R, Yin J, Ruan X, Chen Y, Wan P, Luo Z
Computational and structural biotechnology journal 2023;21:4478-4487
Computational and structural biotechnology journal 2023;21:4478-4487
GAPDH: A common housekeeping gene with an oncogenic role in pan-cancer.
Wang J, Yu X, Cao X, Tan L, Jia B, Chen R, Li J
Computational and structural biotechnology journal 2023;21:4056-4069
Computational and structural biotechnology journal 2023;21:4056-4069
Drug repurposing screens to identify potential drugs for chronic kidney disease by targeting prostaglandin E2 receptor.
Huang HJ, Lee YH, Sung LC, Chen YJ, Chiu YJ, Chiu HW, Zheng CM
Computational and structural biotechnology journal 2023;21:3490-3502
Computational and structural biotechnology journal 2023;21:3490-3502
Rational design, synthesis and structural characterization of peptides and peptidomimetics to target Hsp90/Cdc37 interaction for treating hepatocellular carcinoma.
Sukumaran S, Tan M, Ben-Uliel SF, Zhang H, De Zotti M, Chua MS, So SK, Qvit N
Computational and structural biotechnology journal 2023;21:3159-3172
Computational and structural biotechnology journal 2023;21:3159-3172
Identification of potential diagnostic and prognostic biomarkers for sepsis based on machine learning.
Ke L, Lu Y, Gao H, Hu C, Zhang J, Zhao Q, Sun Z, Peng Z
Computational and structural biotechnology journal 2023;21:2316-2331
Computational and structural biotechnology journal 2023;21:2316-2331
Identification of Potential Biomarkers of Septic Shock Based on Pathway and Transcriptome Analyses of Immune-Related Genes.
Wang J, Cai J, Yue L, Zhou X, Hu C, Zhu H
Genetics research 2023;2023:9991613
Genetics research 2023;2023:9991613
Penfluroidol Attenuates the Imbalance of the Inflammatory Response by Repressing the Activation of the NLRP3 Inflammasome and Reduces Oxidative Stress via the Nrf2/HO-1 Signaling Pathway in LPS-Induced Macrophages.
Li Q, Wu L, Cheng B, Tao S, Wang W, Luo Z, Fan J
Mediators of inflammation 2023;2023:9940858
Mediators of inflammation 2023;2023:9940858
High Expression of DLGAP5 Indicates Poor Prognosis and Immunotherapy in Lung Adenocarcinoma and Promotes Proliferation through Regulation of the Cell Cycle.
Tang X, Zhou H, Liu Y
Disease markers 2023;2023:9292536
Disease markers 2023;2023:9292536
Ginkgolide B Blocks Vascular Remodeling after Vascular Injury via Regulating Tgfβ1/Smad Signaling Pathway.
Wang Q, Ni S, Ling L, Wang S, Xie H, Ren Z
Cardiovascular therapeutics 2023;2023:8848808
Cardiovascular therapeutics 2023;2023:8848808
Transcription Factor E2F1 Regulates the Expression of ADRB2.
Du J, Rui F, Hao Z, Hang Y, Shu J
International journal of analytical chemistry 2023;2023:8210685
International journal of analytical chemistry 2023;2023:8210685
Fisetin Prevents Angiogenesis in Diabetic Retinopathy by Downregulating VEGF.
Lai M, Lan C, Zhong J, Wu L, Lin C
Journal of ophthalmology 2023;2023:7951928
Journal of ophthalmology 2023;2023:7951928
AdipoRon Engages Microglia to Antinociception through the AdipoR1/AMPK Pathway in SNI Mice.
Fang Q, Li J, Wang Y, Liu X, Shi Y, Chen J, Zhan H, Zeng Y, Wu W
Mediators of inflammation 2023;2023:7661791
Mediators of inflammation 2023;2023:7661791
NF-κB Inhibitor Myrislignan Induces Ferroptosis of Glioblastoma Cells via Regulating Epithelial-Mesenchymal Transformation in a Slug-Dependent Manner.
Zhou Y, Qian W, Li X, Wei W
Oxidative medicine and cellular longevity 2023;2023:7098313
Oxidative medicine and cellular longevity 2023;2023:7098313
Mechanism of Xiezhuo Huayu Yiqi Tongluo Formula in the Treatment of Uric Acid Nephropathy Based on Network Pharmacology, Molecular Docking, and In Vivo Experiments.
Fan L, Guo Y, Wu Q, Hu T, Chen X, Guo J, Liu Y, Lu Y, Lin M
Evidence-based complementary and alternative medicine : eCAM 2023;2023:6931644
Evidence-based complementary and alternative medicine : eCAM 2023;2023:6931644
JFD, a Novel Natural Inhibitor of Keap1 Alkylation, Suppresses Intracellular Mycobacterium Tuberculosis Growth through Keap1/Nrf2/SOD2-Mediated ROS Accumulation.
Wan H, Cai Y, Xiao L, Ling Y, Ge L, Mo S, Xie Q, Peng S, Zhou B, Zeng X, Chen X
Oxidative medicine and cellular longevity 2023;2023:6726654
Oxidative medicine and cellular longevity 2023;2023:6726654
Mini-αA Upregulates the miR-155-5p Target Gene CDK2 and Plays an Antiapoptotic Role in Retinal Pigment Epithelial Cells during Oxidative Stress.
Chen Q, Lin H, Li S, Deng X, Zhang J
Journal of ophthalmology 2023;2023:6713094
Journal of ophthalmology 2023;2023:6713094
Tumor Necrosis Factor-α Promotes the Tumorigenesis, Lymphangiogenesis, and Lymphatic Metastasis in Cervical Cancer via Activating VEGFC-Mediated AKT and ERK Pathways.
Chen X, Lin L, Wu Q, Li S, Wang H, Sun Y
Mediators of inflammation 2023;2023:5679966
Mediators of inflammation 2023;2023:5679966
Transcutaneous Electrical Nerve Stimulation (TENS) Alleviates Brain Ischemic Injury by Regulating Neuronal Oxidative Stress, Pyroptosis, and Mitophagy.
Tan Z, Dong F, Wu L, Feng Y, Zhang M, Zhang F
Mediators of inflammation 2023;2023:5677865
Mediators of inflammation 2023;2023:5677865
The Interaction of Apelin and FGFR1 Ameliorated the Kidney Fibrosis through Suppression of TGFβ-Induced Endothelial-to-Mesenchymal Transition.
Gao R, Wu Y, Yang Q, Chen L, Chen J, Wang B, Liu Z, Jin J, Li J, Wu G
Oxidative medicine and cellular longevity 2023;2023:5012474
Oxidative medicine and cellular longevity 2023;2023:5012474
The Upregulation of GSTO2 is Associated with Colon Cancer Progression and a Poor Prognosis.
Peng X, Zhu J, Liu S, Liu Z, Luo C, Wu X, Yu Z, Zhu Z
Journal of oncology 2023;2023:4931650
Journal of oncology 2023;2023:4931650
Downregulation of VRK1 Inhibits Progression of Lung Squamous Cell Carcinoma through DNA Damage.
Du N, Zhang B, Zhang Y
Canadian respiratory journal 2023;2023:4533504
Canadian respiratory journal 2023;2023:4533504
Hemoglobin Derived from Subarachnoid Hemorrhage-Induced Pyroptosis of Neural Stem Cells via ROS/NLRP3/GSDMD Pathway.
Yue T, Li X, Chen X, Zhu T, Li W, Wang B, Hang C
Oxidative medicine and cellular longevity 2023;2023:4383332
Oxidative medicine and cellular longevity 2023;2023:4383332
Silencing MYOT Expression May Inhibit Autophagy in Human Skeletal Muscle Cells.
Lin ZJ, Xu JM, Ji HY, Jiang YQ, Su J, Fan LL, Yu R
Disease markers 2023;2023:3350685
Disease markers 2023;2023:3350685
Bone Mesenchymal Stem Cell-Derived Small Extracellular Vesicles Ameliorated Lipopolysaccharide-Induced Lung Injury Via the miR-21-5p/PCSK6 Pathway.
Cai B, Song W, Chen S, Sun J, Zhou R, Han Z, Wan J
Journal of immunology research 2023;2023:3291137
Journal of immunology research 2023;2023:3291137
The Microbiota-Dependent Treatment of Wuzhuyu Decoction for Chronic Migraine Model Rat Associated with Anxiety-Depression Like Behavior.
Nan N, Wang Q, Li MJ, Xu YS, Guo XM, Xu R, Ma Z, Wang SH, Li J, Zhao H, Gong MX
Oxidative medicine and cellular longevity 2023;2023:2302653
Oxidative medicine and cellular longevity 2023;2023:2302653
miR-1 Inhibits the Ferroptosis of Chondrocyte by Targeting CX43 and Alleviates Osteoarthritis Progression.
Zhou M, Zhai C, Shen K, Liu G, Liu L, He J, Chen J, Xu Y
Journal of immunology research 2023;2023:2061071
Journal of immunology research 2023;2023:2061071
Long Noncoding RNA LINC00578 Inhibits Ferroptosis in Pancreatic Cancer via Regulating SLC7A11 Ubiquitination.
Li H, Wei Y, Wang J, Yao J, Zhang C, Yu C, Tang Y, Zhu D, Yang J, Zhou J
Oxidative medicine and cellular longevity 2023;2023:1744102
Oxidative medicine and cellular longevity 2023;2023:1744102
Aldolase A Promotes Colorectal Cancer Progression through Targeting COPS6 and Regulating MAPK Signaling Pathway.
Lu Y, Zhang Y, Wang X, Zhang H, Zhu Y, Zhang J, Sha H, Zou R, Gan Y, Sui Y, Wang J, Du T, Wu J, Feng J
Disease markers 2023;2023:1702125
Disease markers 2023;2023:1702125
Metformin Ameliorates D-Galactose-Induced Senescent Human Bone Marrow-Derived Mesenchymal Stem Cells by Enhancing Autophagy.
Ye P, Feng L, Zhang D, Li R, Wen Y, Tong X, Shi S, Dong C
Stem cells international 2023;2023:1429642
Stem cells international 2023;2023:1429642
Resveratrol Suppresses Bupivacaine-Induced Spinal Neurotoxicity in Rats by Inhibiting Endoplasmic Reticulum Stress via SIRT1 Modulation.
Luo Y, Zhao Y, Lai J, Wei L, Zhou G, Yu Y, Liu J
BioMed research international 2023;2023:1176232
BioMed research international 2023;2023:1176232
Melatonin Ameliorates Ovarian Hyperstimulation Syndrome (OHSS) through SESN2 Regulated Antiapoptosis.
Zheng M, Liu M, Zhang C
Obstetrics and gynecology international 2023;2023:1121227
Obstetrics and gynecology international 2023;2023:1121227
APEX2-Mediated Proximity Labeling of Wnt Receptor Interactors Upon Pathway Activation.
Rim EY, Nusse R
microPublication biology 2023;2023
microPublication biology 2023;2023
NAT10-mediated RNA acetylation enhances HNRNPUL1 mRNA stability to contribute cervical cancer progression.
Long Y, Ren Y, Wei Q, Mobet Y, Liu Y, Zhao H, Liu T, Cheng L, Yi P
International journal of medical sciences 2023;20(8):1079-1090
International journal of medical sciences 2023;20(8):1079-1090
Integrated analysis of FKBP1A/SLC3A2 axis in everolimus inducing ferroptosis of breast cancer and anti-proliferation of T lymphocyte.
Chen Z, Li R, Fang M, Wang Y, Bi A, Yang L, Song T, Li Y, Li Q, Lin B, Jia Y, Fu S, Fu S, Xiong H
International journal of medical sciences 2023;20(8):1060-1078
International journal of medical sciences 2023;20(8):1060-1078
ZNF460-regulated COMMD7 Promotes Acute Myeloid Leukemia Proliferation Via the NF-κB Signaling Pathway.
Shao X, Zhong L, Chu X, Wan P, Chen S, Zhou Z, Zhang H, Wang M, Liu B
International journal of medical sciences 2023;20(4):520-529
International journal of medical sciences 2023;20(4):520-529
Activating SIRT1 deacetylates NF-κB p65 to alleviate liver inflammation and fibrosis via inhibiting NLRP3 pathway in macrophages.
He S, Wang Y, Liu J, Li P, Luo X, Zhang B
International journal of medical sciences 2023;20(4):505-519
International journal of medical sciences 2023;20(4):505-519
Upregulated desmin/integrin β1/MAPK axis promotes elastic cartilage regeneration with increased ECM mechanical strength.
Zhang W, Lu W, Yu Q, Liu X, Jiang H
International journal of biological sciences 2023;19(9):2740-2755
International journal of biological sciences 2023;19(9):2740-2755
Inhibition of JNK/c-Jun-ATF2 Overcomes Cisplatin Resistance in Liver Cancer through down-Regulating Galectin-1.
Yang F, Li M, Xu D, Jiang Z, Jiang H, Xiao Y, Mei C, Yang M, Chen C, Zhou B, He B, Shan H, Pang P, Li D
International journal of biological sciences 2023;19(8):2366-2381
International journal of biological sciences 2023;19(8):2366-2381
NLRP3 Inflammasome Mediates Silica-induced Lung Epithelial Injury and Aberrant Regeneration in Lung Stem/Progenitor Cell-derived Organotypic Models.
Zhou H, Zhang Q, Huang W, Zhou S, Wang Y, Zeng X, Wang H, Xie W, Kong H
International journal of biological sciences 2023;19(6):1875-1893
International journal of biological sciences 2023;19(6):1875-1893
Parkin increases the risk of colitis by downregulation of VDR via autophagy-lysosome degradation.
Ma Z, Wu J, Wu Y, Sun X, Rao Z, Sun N, Fu Y, Zhang Z, Li J, Xiao M, Zeng Q, Wu Y, Han C, Ding D, Zhang H, Yuan H, Zhang J, Yang S, Chen Y
International journal of biological sciences 2023;19(5):1633-1644
International journal of biological sciences 2023;19(5):1633-1644
IGF2BP3 Regulates TMA7-mediated Autophagy and Cisplatin Resistance in Laryngeal Cancer via m6A RNA Methylation.
Yang L, Yan B, Qu L, Ren J, Li Q, Wang J, Kan X, Liu M, Wang Y, Sun Y, Wang C, Wang P
International journal of biological sciences 2023;19(5):1382-1400
International journal of biological sciences 2023;19(5):1382-1400
The FGFR1 Signaling Pathway Upregulates the Oncogenic Transcription Factor FOXQ1 to Promote Breast Cancer Cell Growth.
Lin Y, Lin F, Zhang Z, Peng L, Yang W, Yang M, Luo B, Wu T, Li D, Li X, Ran B, Anuchapreeda S, Chaiwongsa R, Khamphikham P, Duangmano S, Xu J, He T, Pornprasert S
International journal of biological sciences 2023;19(3):744-759
International journal of biological sciences 2023;19(3):744-759
Upregulation of LRRC8A by m(5)C modification-mediated mRNA stability suppresses apoptosis and facilitates tumorigenesis in cervical cancer.
Chen Y, Zuo X, Wei Q, Xu J, Liu X, Liu S, Wang H, Luo Q, Wang Y, Yang Y, Zhao H, Xu J, Liu T, Yi P
International journal of biological sciences 2023;19(2):691-704
International journal of biological sciences 2023;19(2):691-704
FGF2 Alleviates Microvascular Ischemia-Reperfusion Injury by KLF2-mediated Ferroptosis Inhibition and Antioxidant Responses.
Chen F, Zhan J, Liu M, Mamun AA, Huang S, Tao Y, Zhao J, Zhang Y, Xu Y, He Z, Du S, Lu W, Li X, Chen Z, Xiao J
International journal of biological sciences 2023;19(13):4340-4359
International journal of biological sciences 2023;19(13):4340-4359
FOXO3 regulates Smad3 and Smad7 through SPON1 circular RNA to inhibit idiopathic pulmonary fibrosis.
Li H, Li J, Hu Y, Zhang R, Gu X, Wei Y, Zhang S, Chen X, Wei L, Li X, Gu S, Jin J, Huang H, Zhou H, Yang C
International journal of biological sciences 2023;19(10):3042-3056
International journal of biological sciences 2023;19(10):3042-3056
BST2 induced macrophage M2 polarization to promote the progression of colorectal cancer.
He X, Chen H, Zhong X, Wang Y, Hu Z, Huang H, Zhao S, Wei P, Shi D, Li D
International journal of biological sciences 2023;19(1):331-345
International journal of biological sciences 2023;19(1):331-345
TGFβ Governs the Pleiotropic Activity of NDRG1 in Triple-Negative Breast Cancer Progression.
López-Tejada A, Griñán-Lisón C, González-González A, Cara FE, Luque RJ, Rosa-Garrido C, Blaya-Cánovas JL, Navarro-Ocón A, Valenzuela-Torres M, Parra-López M, Calahorra J, Blancas I, Marchal JA, Granados-Principal S
International journal of biological sciences 2023;19(1):204-224
International journal of biological sciences 2023;19(1):204-224
NOP2/Sun RNA methyltransferase 2 is a potential pan-cancer prognostic biomarker and is related to immunity.
Zheng L, Li M, Wei J, Chen S, Xue C, Duan Y, Tang F, Li G, Xiong W, She K, Deng H, Zhou M
PloS one 2023;18(9):e0292212
PloS one 2023;18(9):e0292212
Suppression of migration and invasion by taraxerol in the triple-negative breast cancer cell line MDA-MB-231 via the ERK/Slug axis.
Xia YT, Zhang YQ, Chen L, Min L, Huang D, Zhang Y, Li C, Li ZH
PloS one 2023;18(9):e0291693
PloS one 2023;18(9):e0291693
USP4 promotes the proliferation and glucose metabolism of gastric cancer cells by upregulating PKM2.
Chen Y, Guo Y, Yuan M, Guo S, Cui S, Chen D
PloS one 2023;18(8):e0290688
PloS one 2023;18(8):e0290688
Ketogenic diet ameliorates attention deficit hyperactivity disorder in rats via regulating gut microbiota.
Liu Y, Yang C, Meng Y, Dang Y, Yang L
PloS one 2023;18(8):e0289133
PloS one 2023;18(8):e0289133
Caffeic acid phenethyl ester suppresses metastasis of breast cancer cells by inactivating FGFR1 via MD2.
Fang Q, Xin W, Chen L, Fu Y, Qi Y, Ding H, Fang L
PloS one 2023;18(7):e0289031
PloS one 2023;18(7):e0289031
Deficient AMPK activity contributes to hyperexcitability in peripheral nociceptive sensory neurons and thermal hyperalgesia in lupus mice.
Viatchenko-Karpinski V, Kong L, Weng HR
PloS one 2023;18(7):e0288356
PloS one 2023;18(7):e0288356
Exosome-delivered circRPS5 inhibits the progression of melanoma via regulating the miR-151a/NPTX1 axis.
Zhu H, Zhang P, Shi J, Kou D, Bai X
PloS one 2023;18(6):e0287347
PloS one 2023;18(6):e0287347
Peptide encoded by lncRNA BVES-AS1 promotes cell viability, migration, and invasion in colorectal cancer cells via the SRC/mTOR signaling pathway.
Zheng W, Guo Y, Zhang G, Bai J, Song Y, Song X, Zhu Q, Bao X, Wu G, Zhang C
PloS one 2023;18(6):e0287133
PloS one 2023;18(6):e0287133
FAK downregulation suppresses stem-like properties and migration of human colorectal cancer cells.
Xu C, Zhang W, Liu C
PloS one 2023;18(4):e0284871
PloS one 2023;18(4):e0284871
Inhibition of mycobacteria proliferation in macrophages by low cisplatin concentration through phosphorylated p53-related apoptosis pathway.
Bao J, He Y, Yang C, Lu N, Li A, Gao S, Hosyanto FF, Tang J, Si J, Tang X, Fu H, Xu L
PloS one 2023;18(1):e0281170
PloS one 2023;18(1):e0281170
miR-192 inhibits the activation of hepatic stellate cells by targeting Rictor.
Kang H, Luo J, Wang C, Hong Y, Ye M, Ding Y, Zhao Q, Chang Y
Open medicine (Warsaw, Poland) 2023;18(1):20230879
Open medicine (Warsaw, Poland) 2023;18(1):20230879
WTAP affects intracranial aneurysm progression by regulating m6A methylation modification.
Yuan X, Bao Q, Lu B, Xiang C, Hou X, Wei W
Open medicine (Warsaw, Poland) 2023;18(1):20230818
Open medicine (Warsaw, Poland) 2023;18(1):20230818
miR-199a-5p inhibits aortic valve calcification by targeting ATF6 and GRP78 in valve interstitial cells.
Chu H, Fan X, Zhang Z, Han L
Open medicine (Warsaw, Poland) 2023;18(1):20230777
Open medicine (Warsaw, Poland) 2023;18(1):20230777
Alkbh5 plays indispensable roles in maintaining self-renewal of hematopoietic stem cells.
Yang B, Liu Y, Xiao F, Liu Z, Chen Z, Li Z, Zhou C, Kuang M, Shu Y, Liu S, Zou L
Open medicine (Warsaw, Poland) 2023;18(1):20230766
Open medicine (Warsaw, Poland) 2023;18(1):20230766
HDAC5-mediated PRAME regulates the proliferation, migration, invasion, and EMT of laryngeal squamous cell carcinoma via the PI3K/AKT/mTOR signaling pathway.
Yu L, Cao H, Yang JW, Meng WX, Yang C, Wang JT, Yu MM, Wang BS
Open medicine (Warsaw, Poland) 2023;18(1):20230665
Open medicine (Warsaw, Poland) 2023;18(1):20230665
Pharmacological inhibition of the ubiquitin-specific protease 8 effectively suppresses glioblastoma cell growth.
Long Y, Hu Z, Yang D, Wang F, Zhao C, Zhang Y, Zhang Y, Ma H, Lv H
Open life sciences 2023;18(1):20220562
Open life sciences 2023;18(1):20220562
Effect of the Lipoxin Receptor Agonist BML-111 on Cigarette Smoke Extract-Induced Macrophage Polarization and Inflammation in RAW264.7 Cells.
Cao E, Xu J, Gong Y, Yuan J, Chen A, Liu J, Fan Y, Fan X, Kuang X
International journal of chronic obstructive pulmonary disease 2023;18:919-932
International journal of chronic obstructive pulmonary disease 2023;18:919-932
Osteoblasts-Derived Exosomal lncRNA-MALAT1 Promotes Osteoclastogenesis by Targeting the miR-124/NFATc1 Signaling Axis in Bone Marrow-Derived Macrophages.
Zhang C, Pan L, Zhang H, Ke T, Yang Y, Zhang L, Chen L, Tan J
International journal of nanomedicine 2023;18:781-795
International journal of nanomedicine 2023;18:781-795
Nanocurcumin Reduces High Glucose and Particulate Matter-Induced Endothelial Inflammation: Mitochondrial Function and Involvement of miR-221/222.
Lai TC, Lee CW, Hsu MH, Chen YC, Lin SR, Lin SW, Lee TL, Lin SY, Hsu SH, Tsai JS, Chen YL
International journal of nanomedicine 2023;18:7379-7402
International journal of nanomedicine 2023;18:7379-7402
Multifunctional Lithium-Doped Mesoporous Nanoparticles for Effective Dentin Regeneration in vivo.
Liang Z, Chen D, Jiang Y, Su Z, Pi Y, Luo T, Jiang Q, Yang L, Guo L
International journal of nanomedicine 2023;18:5309-5325
International journal of nanomedicine 2023;18:5309-5325
Osteoclast-Derived Exosomal miR-5134-5p Interferes with Alveolar Bone Homeostasis by Targeting the JAK2/STAT3 Axis.
Pan L, Zhang C, Zhang H, Ke T, Bian M, Yang Y, Chen L, Tan J
International journal of nanomedicine 2023;18:3727-3744
International journal of nanomedicine 2023;18:3727-3744
Exosome-Delivered circSTAU2 Inhibits the Progression of Gastric Cancer by Targeting the miR-589/CAPZA1 Axis.
Zhang C, Wei G, Zhu X, Chen X, Ma X, Hu P, Liu W, Yang W, Ruan T, Zhang W, Wu C, Tao K
International journal of nanomedicine 2023;18:127-142
International journal of nanomedicine 2023;18:127-142
Dexmedetomidine Ameliorates Cardiac Ischemia/Reperfusion Injury by Enhancing Autophagy Through Activation of the AMPK/SIRT3 Pathway.
He H, Liu P, Li P
Drug design, development and therapy 2023;17:3205-3218
Drug design, development and therapy 2023;17:3205-3218
Luteolin Alleviates Liver Fibrosis in Rat Hepatic Stellate Cell HSC-T6: A Proteomic Analysis.
Batudeligen, Han Z, Chen H, Narisu, Xu Y, Anda, Han G
Drug design, development and therapy 2023;17:1819-1829
Drug design, development and therapy 2023;17:1819-1829
The Protective Effect of Selenium Nanoparticles in Osteoarthritis: In vitro and in vivo Studies.
Li Y, Zhu S, Luo J, Tong Y, Zheng Y, Ji L, He Z, Jing Q, Huang J, Zhang Y, Bi Q
Drug design, development and therapy 2023;17:1515-1529
Drug design, development and therapy 2023;17:1515-1529
Identification of immune-related biomarkers in peripheral blood of schizophrenia using bioinformatic methods and machine learning algorithms.
Zhu X, Wang CL, Yu JF, Weng J, Han B, Liu Y, Tang X, Pan B
Frontiers in cellular neuroscience 2023;17:1256184
Frontiers in cellular neuroscience 2023;17:1256184
Liuwei Dihuang formula ameliorates chronic stress-induced emotional and cognitive impairments in mice by elevating hippocampal O-GlcNAc modification.
Huang Y, Wang J, Liu F, Wang C, Xiao Z, Zhou W
Frontiers in neuroscience 2023;17:1134176
Frontiers in neuroscience 2023;17:1134176
The SIK1/CRTC2/CREB1 and TWIST1/PI3K/Akt/GSK3β signaling pathways mediated by microRNA-25-3p are altered in the schizophrenic rat brain.
Pan B, Zhu X, Han B, Weng J, Wang Y, Liu Y
Frontiers in cellular neuroscience 2023;17:1087335
Frontiers in cellular neuroscience 2023;17:1087335
Comparison of extruded cell nanovesicles and exosomes in their molecular cargos and regenerative potentials.
Wang X, Hu S, Zhu D, Li J, Cheng K, Liu G
Nano research 2023;16(5):7248-7259
Nano research 2023;16(5):7248-7259
Acupuncture Relieves Cervical Spondylosis Radiculopathy by Regulating Spinal Microglia Activation Through MAPK Signaling Pathway in Rats.
Shi T, Liu Y, Ji B, Wang J, Ge Y, Fang Y, Xie Y, Xiao H, Wu L, Wang Y
Journal of pain research 2023;16:3945-3960
Journal of pain research 2023;16:3945-3960
NEK6 Promotes the Progression of Osteosarcoma Through Activating STAT3 Signaling Pathway by Down-Regulation of miR-26a-5p.
Zhu M, Sun Y, Xue H, Wu G, Wang Z, Shi J, Ma J, Gu B, Yan X
International journal of general medicine 2023;16:2831-2848
International journal of general medicine 2023;16:2831-2848
Deep Sea Water Inhibited Pancreatic β-Cell Apoptosis and Regulated Glucose Homeostasis by Affecting Lipid Metabolism in Db/Db Mice.
Shi M, Hu B, Hong Y, Wang M, Yao Y
Diabetes, metabolic syndrome and obesity : targets and therapy 2023;16:245-258
Diabetes, metabolic syndrome and obesity : targets and therapy 2023;16:245-258
The Allelic Expression of RNA Editing Gene ADARB1 in Hepatocellular Carcinoma Treated with Transarterial Chemoembolization.
Zeng J, Han L, Wang T, Huang L, Zheng Y, Zhang N, Li Z, Yang M
Pharmacogenomics and personalized medicine 2023;16:229-238
Pharmacogenomics and personalized medicine 2023;16:229-238
Identification of Critical Biomarkers and Mechanisms of Fructus Ligustri Lucidi on Vitiligo Using Integrated Bioinformatics Analysis.
Liang TS, Tang N, Xian MH, Wen WL, Huang CJ, Cai LH, Li QL, Wu YH
Clinical, cosmetic and investigational dermatology 2023;16:2061-2071
Clinical, cosmetic and investigational dermatology 2023;16:2061-2071
Transmission of Exosomal TPX2 Promotes Metastasis and Resistance of NSCLC Cells to Docetaxel.
Hu J, He Q, Tian T, Chang N, Qian L
OncoTargets and therapy 2023;16:197-210
OncoTargets and therapy 2023;16:197-210
circHECTD1 Promotes the Proliferation and Migration of Human Brain Vascular Smooth Muscle Cells via Interacting with KHDRBS3 to Stabilize EZH2 mRNA Expression.
Feng M, Tu W, Zhou Q, Du Y, Xu K, Wang Y
Journal of inflammation research 2023;16:1311-1323
Journal of inflammation research 2023;16:1311-1323
Chemokine receptor CXCR2 in primary sensory neurons of trigeminal ganglion mediates orofacial itch.
Li DJ, Zhong ZJ, Wang XL, Wei N, Zhao SJ, Shan TT, Liu YP, Yu YQ
Frontiers in molecular neuroscience 2023;16:1279237
Frontiers in molecular neuroscience 2023;16:1279237
Cardiolipin externalization mediates prion protein (PrP) peptide 106-126-associated mitophagy and mitochondrial dysfunction.
Yang D, Li J, Li Z, Zhao M, Wang D, Sun Z, Wen P, Gou F, Dai Y, Ji Y, Li W, Zhao D, Yang L
Frontiers in molecular neuroscience 2023;16:1163981
Frontiers in molecular neuroscience 2023;16:1163981
Ectopic expression of Nav1.7 in spinal dorsal horn neurons induced by NGF contributes to neuropathic pain in a mouse spinal cord injury model.
Fu Y, Sun L, Zhu F, Xia W, Wen T, Xia R, Yu X, Xu D, Peng C
Frontiers in molecular neuroscience 2023;16:1091096
Frontiers in molecular neuroscience 2023;16:1091096
Spinal cannabinoid receptor 2 activation alleviates neuropathic pain by regulating microglia and suppressing P2X7 receptor.
Zhou Y, Xu Y, Yang J, Yu Z, Wang W, Yuan M, Wang Y, Bai Q, Li Z
Frontiers in molecular neuroscience 2023;16:1061220
Frontiers in molecular neuroscience 2023;16:1061220
Increasing autophagy ameliorates all-trans-retinal-activated NLRP3 inflammasomes in human THP-1 macrophages.
Xia Q, Li J, Zhang L, Zhou Y, Yang Z, Xie J
American journal of translational research 2023;15(6):4380-4389
American journal of translational research 2023;15(6):4380-4389
Mesenchymal stem cell-derived exosomes ameliorate TGF-β1-induced endometrial fibrosis by altering their miRNA profile.
Zhou L, Dong L, Li H, Liu H, Yang J, Huang Z
American journal of translational research 2023;15(5):3203-3216
American journal of translational research 2023;15(5):3203-3216
Vitamin D Receptor Activation Targets ROS-Mediated Crosstalk Between Autophagy and Apoptosis in Hepatocytes in Cholestasic Mice.
Zheng Z, Xie J, Ma L, Hao Z, Zhang W, Li L
Cellular and molecular gastroenterology and hepatology 2023;15(4):887-901
Cellular and molecular gastroenterology and hepatology 2023;15(4):887-901
The mechanism of chemokine receptor ACKR2 in cognitive impairment in young rats with traumatic brain injury.
Quan L, Zhao Y, Ouyang C, Ying D, Xiong Z, Li X, Liao Z, Luo J, Liu H
American journal of translational research 2023;15(3):1654-1666
American journal of translational research 2023;15(3):1654-1666
TREM2 as an independent predictor of poor prognosis promotes the migration via the PI3K/AKT axis in prostate cancer.
Gao HT, Yang Z, Sun H, Zhang Y, Wang Z, Liu WY, Wen HZ, Qu CB, Wang XL
American journal of translational research 2023;15(2):779-798
American journal of translational research 2023;15(2):779-798
Mannan-Binding Lectin Reduces Epithelial-Mesenchymal Transition in Pulmonary Fibrosis via Inactivating the Store-Operated Calcium Entry Machinery.
Liu Y, Xie X, Wang P, Luo J, Chen Y, Xu Q, Zhou J, Lu X, Zhao J, Chen Z, Zuo D
Journal of innate immunity 2023;15(1):37-49
Journal of innate immunity 2023;15(1):37-49
CD24 May Serve as an Immunotherapy Target in Triple-Negative Breast Cancer by Regulating the Expression of PD-L1.
Zhu X, Yu J, Ai F, Wang Y, Lv W, Yu G, Cao X, Lin J
Breast cancer (Dove Medical Press) 2023;15:967-984
Breast cancer (Dove Medical Press) 2023;15:967-984
CCL5 promotes LFA-1 expression in Th17 cells and induces LCK and ZAP70 activation in a mouse model of Parkinson's disease.
Zhao J, An K, Mao Z, Qu Y, Wang D, Li J, Min Z, Xue Z
Frontiers in aging neuroscience 2023;15:1250685
Frontiers in aging neuroscience 2023;15:1250685
The γ-Adducin 1-357 fragment promotes tau pathology.
Yu H, Xiong M, Liu C, Xia D, Meng L, Zhang Z
Frontiers in aging neuroscience 2023;15:1241750
Frontiers in aging neuroscience 2023;15:1241750
CC-115 Mediates GSDME-Dependent Pyroptosis in Lung Adenocarcinoma Through the Akt/Bax Pathway.
Zhang T, Liu MQ, Xie GS, Wu DM, Luo PW, Liu T, Deng SH, Wang YY, He S, Zhou Y, Zhou J, Xu Y
Journal of Cancer 2023;14(8):1350-1361
Journal of Cancer 2023;14(8):1350-1361
CRTC2 promotes paclitaxel resistance by inducing autophagy in ovarian cancer in part via the PI3K-AKT signaling axis.
Ou C, Peng C, Wang Y, Lu S, Yu X, He Q, He A, Zhang L
Journal of Cancer 2023;14(6):1011-1023
Journal of Cancer 2023;14(6):1011-1023
Role of DEP domain-containing protein 1B (DEPDC1B) in epithelial ovarian cancer.
Wu Y, Yin H, Zhang X, Shen R, Zhu X, Jia M
Journal of Cancer 2023;14(5):784-792
Journal of Cancer 2023;14(5):784-792
Construction of the metabolism-related models for predicting prognosis and infiltrating immune phenotype in lung squamous cell carcinoma.
Ma Z, Wang L, Huang X, Ji H, Wang H, Yang Y, Ma Y, Chen J
Journal of Cancer 2023;14(18):3539-3549
Journal of Cancer 2023;14(18):3539-3549
Ablation of the GDP-fucose transporter suppresses lung cancer cell proliferation and migration by reducing expression of PD-L1.
Zhang Y, Zhang N, Song W, Yousuf S, Li W
Journal of Cancer 2023;14(17):3295-3308
Journal of Cancer 2023;14(17):3295-3308
PRMT7 Inhibits the Proliferation and Migration of Gastric Cancer Cells by Suppressing the PI3K/AKT Pathway via PTEN.
Wang X, Xu W, Zhu C, Cheng Y, Qi J
Journal of Cancer 2023;14(15):2833-2844
Journal of Cancer 2023;14(15):2833-2844
Identification and characterization of a new variation in DPM2 gene in two Chinese siblings with mild intellectual impairment.
Zhao P, Hu Y, Hu J, Li C, Huang Y, Zhang L, Luo S, Zhu H, Jiang J, He X
Frontiers in genetics 2023;14:930692
Frontiers in genetics 2023;14:930692
Bacteroides acidifaciens and its derived extracellular vesicles improve DSS-induced colitis.
Zheng C, Zhong Y, Xie J, Wang Z, Zhang W, Pi Y, Zhang W, Liu L, Luo J, Xu W
Frontiers in microbiology 2023;14:1304232
Frontiers in microbiology 2023;14:1304232
Prognostic biomarker DARS2 correlated with immune infiltrates in bladder tumor.
Yang H, Ma L, Deng W, Fu B, Nie J, Liu X
Frontiers in immunology 2023;14:1301945
Frontiers in immunology 2023;14:1301945
FANCI serve as a prognostic biomarker correlated with immune infiltrates in skin cutaneous melanoma.
Cai Z, Duan Y, Li W, Liu Z, Gong Z, Hong S, He X, Xuanyuan X, Chen Y, Bi X, Wang W
Frontiers in immunology 2023;14:1295831
Frontiers in immunology 2023;14:1295831
Central and peripheral analgesic active components of triterpenoid saponins from Stauntonia chinensis and their action mechanism.
Gong JH, Zhang CM, Wu B, Zhang ZX, Zhou ZY, Zhu JH, Liu H, Rong Y, Yin Q, Chen YT, Zheng R, Yang GZ, Yang XF, Chen S
Frontiers in pharmacology 2023;14:1275041
Frontiers in pharmacology 2023;14:1275041
Exploring the immune microenvironment of osteosarcoma through T cell exhaustion-associated gene expression: a study on prognosis prediction.
Zhu J, Yuan J, Arya S, Du Z, Liu X, Jia J
Frontiers in immunology 2023;14:1265098
Frontiers in immunology 2023;14:1265098
Sigma-1 receptor knockout disturbs gut microbiota, remodels serum metabolome, and exacerbates isoprenaline-induced heart failure.
Yang JZ, Zhang KK, Shen HW, Liu Y, Li XW, Chen LJ, Liu JL, Li JH, Zhao D, Wang Q, Zhou CS
Frontiers in microbiology 2023;14:1255971
Frontiers in microbiology 2023;14:1255971
Exploring the mechanism of aloe-emodin in the treatment of liver cancer through network pharmacology and cell experiments.
Zhu M, He Q, Wang Y, Duan L, Rong K, Wu Y, Ding Y, Mi Y, Ge X, Yang X, Yu Y
Frontiers in pharmacology 2023;14:1238841
Frontiers in pharmacology 2023;14:1238841
The G285S mutation in nsP1 is sufficient to render Sindbis virus as a stable vector for gene delivery.
Shi X, Sun K, Hu Y, Wang Q, Liao G, Li L, Wen P, Wong LE, Jia F, Xu F
Frontiers in microbiology 2023;14:1229506
Frontiers in microbiology 2023;14:1229506
Induction of RIPK3/MLKL-mediated necroptosis by Erigeron breviscapus injection exhibits potent antitumor effect.
Guo X, Li R, Cui J, Hu C, Yu H, Ren L, Cheng Y, Jiang J, Ding X, Wang L
Frontiers in pharmacology 2023;14:1219362
Frontiers in pharmacology 2023;14:1219362
Identification of molecular subtypes based on PANoptosis-related genes and construction of a signature for predicting the prognosis and response to immunotherapy response in hepatocellular carcinoma.
Zhu J, Huang Q, Peng X, Luo C, Liu Z, Liu D, Yuan H, Yuan R, Cheng X
Frontiers in immunology 2023;14:1218661
Frontiers in immunology 2023;14:1218661
Swine acute diarrhoea syndrome coronavirus (SADS-CoV) Nsp5 antagonizes type I interferon signaling by cleaving DCP1A.
Huang HX, Zhao CC, Lei XX, Zhang XY, Li YY, Lan T, Zhao BP, Lu JY, Sun WC, Lu HJ, Jin NY
Frontiers in immunology 2023;14:1196031
Frontiers in immunology 2023;14:1196031
Cryptotanshinone affects HFL-1 cells proliferation by inhibiting cytokines secretion in RAW264.7 cells and ameliorates inflammation and fibrosis in newborn rats with hyperoxia induced lung injury.
Ma M, Bao T, Li J, Cao L, Yu B, Hu J, Cheng H, Tian Z
Frontiers in pharmacology 2023;14:1192370
Frontiers in pharmacology 2023;14:1192370
Electroacupuncture alleviates ulcerative colitis by targeting CXCL1: evidence from the transcriptome and validation.
Zhang RB, Dong LC, Shen Y, Li HY, Huang Q, Yu SG, Wu QF
Frontiers in immunology 2023;14:1187574
Frontiers in immunology 2023;14:1187574
A high-concentrate diet induces inflammatory injury via regulating Ca(2+)/CaMKKβ-mediated autophagy in mammary gland tissue of dairy cows.
Meng M, Li X, Wang Z, Huo R, Ma N, Chang G, Shen X
Frontiers in immunology 2023;14:1186170
Frontiers in immunology 2023;14:1186170
ANGPTL2+cancer-associated fibroblasts and SPP1+macrophages are metastasis accelerators of colorectal cancer.
Liu X, Qin J, Nie J, Gao R, Hu S, Sun H, Wang S, Pan Y
Frontiers in immunology 2023;14:1185208
Frontiers in immunology 2023;14:1185208
Cholesterol 25-hydroxylase suppresses avian reovirus replication by its enzymatic product 25-hydroxycholesterol.
Wang Y, Zuo W, Zhang Y, Bo Z, Zhang C, Zhang X, Wu Y
Frontiers in microbiology 2023;14:1178005
Frontiers in microbiology 2023;14:1178005
Ferroptosis and its potential role in gestational diabetes mellitus: updated evidence from pathogenesis to therapy.
Zhao Y, Gao Q, Li B, Wang Y, Wang Y
Frontiers in endocrinology 2023;14:1177547
Frontiers in endocrinology 2023;14:1177547
Identification of afatinib-associated ADH1B and potential small-molecule drugs targeting ADH1B for hepatocellular carcinoma.
Zhou Y, Yu L, Huang P, Zhao X, He R, Cui Y, Pan B, Liu C
Frontiers in pharmacology 2023;14:1166454
Frontiers in pharmacology 2023;14:1166454
Jianpi Yangzheng Xiaozheng decoction alleviates gastric cancer progression via suppressing exosomal PD-L1.
Chen Y, Liu J, Chen Y, Zhang R, Tao J, Chen X, Wang H, Sun Q, Wu J, Liu S
Frontiers in pharmacology 2023;14:1159829
Frontiers in pharmacology 2023;14:1159829
Bicyclol attenuates high fat diet-induced non-alcoholic fatty liver disease/non-alcoholic steatohepatitis through modulating multiple pathways in mice.
Wu J, Jia S, Xu B, Yao X, Shao J, Yao J, Cen D, Yao X
Frontiers in pharmacology 2023;14:1157200
Frontiers in pharmacology 2023;14:1157200
Exploration of epithelial-mesenchymal transition-related lncRNA signature and drug sensitivity in breast cancer.
Li C, Zheng L, Xu G, Yuan Q, Di Z, Yang Y, Dong X, Hou J, Wu G
Frontiers in endocrinology 2023;14:1154741
Frontiers in endocrinology 2023;14:1154741
Circulating sepsis-related metabolite sphinganine could protect against intestinal damage during sepsis.
Wang Z, Qi Y, Wang F, Zhang B, Jianguo T
Frontiers in immunology 2023;14:1151728
Frontiers in immunology 2023;14:1151728
A non-invasive strategy for suppressing asthmatic airway inflammation and remodeling: Inhalation of nebulized hypoxic hUCMSC-derived extracellular vesicles.
Xu X, Wang Y, Luo X, Gao X, Gu W, Ma Y, Xu L, Yu M, Liu X, Liu J, Wang X, Zheng T, Mao C, Dong L
Frontiers in immunology 2023;14:1150971
Frontiers in immunology 2023;14:1150971
Doxorubicin resistance in breast cancer is mediated via the activation of FABP5/PPARγ and CaMKII signaling pathway.
Chen NN, Ma XD, Miao Z, Zhang XM, Han BY, Almaamari AA, Huang JM, Chen XY, Liu YJ, Su SW
Frontiers in pharmacology 2023;14:1150861
Frontiers in pharmacology 2023;14:1150861
Xue-Jie-San restricts ferroptosis in Crohn's disease via inhibiting FGL1/NF-κB/STAT3 positive feedback loop.
Gao Y, Zhang Z, Du J, Yang X, Wang X, Wen K, Sun X
Frontiers in pharmacology 2023;14:1148770
Frontiers in pharmacology 2023;14:1148770
VPA improves ferroptosis in tubular epithelial cells after cisplatin-induced acute kidney injury.
Li Y, Li K, Zhao W, Wang H, Xue X, Chen X, Li W, Xu P, Wang K, Liu P, Tian X, Fu R
Frontiers in pharmacology 2023;14:1147772
Frontiers in pharmacology 2023;14:1147772
Chebulagic acid suppresses gastric cancer by inhibiting the AURKA/β-catenin/Wnt pathway.
Zhao J, Shi Y, Ma Y, Pan L, Wang Y, Yuan L, Dong J, Ying J
Frontiers in pharmacology 2023;14:1143427
Frontiers in pharmacology 2023;14:1143427
Targeting NK-1R attenuates renal fibrosis via modulating inflammatory responses and cell fate in chronic kidney disease.
Zhu E, Liu Y, Zhong M, Liu Y, Jiang X, Shu X, Li N, Guan H, Xia Y, Li J, Lan HY, Zheng Z
Frontiers in immunology 2023;14:1142240
Frontiers in immunology 2023;14:1142240
Arctiin-encapsulated DSPE-PEG bubble-like nanoparticles inhibit alveolar epithelial type 2 cell senescence to alleviate pulmonary fibrosis via the p38/p53/p21 pathway.
Xiong D, Gao F, Shao J, Pan Y, Wang S, Wei D, Ye S, Chen Y, Chen R, Yue B, Li J, Chen J
Frontiers in pharmacology 2023;14:1141800
Frontiers in pharmacology 2023;14:1141800
Effects of frog skin peptide temporin-1CEa and its analogs on ox-LDL induced macrophage-derived foam cells.
Yang XF, Liu X, Yan XY, Shang DJ
Frontiers in pharmacology 2023;14:1139532
Frontiers in pharmacology 2023;14:1139532
Integrating RNA-seq and scRNA-seq to explore the mechanism of macrophage ferroptosis associated with COPD.
Fan P, Zhang Y, Ding S, Du Z, Zhou C, Du X
Frontiers in pharmacology 2023;14:1139137
Frontiers in pharmacology 2023;14:1139137
Yue-bi-tang attenuates adriamycin-induced nephropathy edema through decreasing renal microvascular permeability via inhibition of the Cav-1/ eNOS pathway.
Li T, Cheng S, Xu L, Lin P, Shao M
Frontiers in pharmacology 2023;14:1138900
Frontiers in pharmacology 2023;14:1138900
Alleviation of DSS-induced colitis in mice by a new-isolated Lactobacillus acidophilus C4.
Liu Q, Jian W, Wang L, Yang S, Niu Y, Xie S, Hayer K, Chen K, Zhang Y, Guo Y, Tu Z
Frontiers in microbiology 2023;14:1137701
Frontiers in microbiology 2023;14:1137701
Eugenol modulates the NOD1-NF-κB signaling pathway via targeting NF-κB protein in triple-negative breast cancer cells.
Shi X, Zhang W, Bao X, Liu X, Yang M, Yin C
Frontiers in endocrinology 2023;14:1136067
Frontiers in endocrinology 2023;14:1136067
The prognostic and immune significance of C15orf48 in pan-cancer and its relationship with proliferation and apoptosis of thyroid carcinoma.
Li C, Tang Y, Li Q, Liu H, Ma X, He L, Shi H
Frontiers in immunology 2023;14:1131870
Frontiers in immunology 2023;14:1131870
Establishment of sheep nasal mucosa explant model and its application in antiviral research.
Zheng J, Lin J, Ma Y, Yang C, Zhong Q, Li Y, Yang Q
Frontiers in microbiology 2023;14:1124936
Frontiers in microbiology 2023;14:1124936
The reduced SCFA-producing gut microbes are involved in the inflammatory activation in Kawasaki disease.
Wang F, Qian F, Zhang Q, Zhao J, Cen J, Zhang J, Zhou J, Luo M, Jia C, Rong X, Chu M
Frontiers in immunology 2023;14:1124118
Frontiers in immunology 2023;14:1124118
Cinnamomi ramulus inhibits cancer cells growth by inducing G2/M arrest.
Li J, Huang HY, Lin YC, Zuo H, Tang Y, Huang HD
Frontiers in pharmacology 2023;14:1121799
Frontiers in pharmacology 2023;14:1121799
Acacetin exerts antitumor effects on gastric cancer by targeting EGFR.
Zhang G, Dong J, Lu L, Liu Y, Hu D, Wu Y, Zhao A, Xu H
Frontiers in pharmacology 2023;14:1121643
Frontiers in pharmacology 2023;14:1121643
Protective effects of Scutellariae Radix Carbonisata-derived carbon dots on blood-heat and hemorrhage rats.
Zhang M, Cheng J, Luo J, Li C, Hou T, Zhao Y, Wang Y, Qu H, Kong H
Frontiers in pharmacology 2023;14:1118550
Frontiers in pharmacology 2023;14:1118550
Increased expression of cell adhesion molecules in myofasciitis.
Ma X, Gao H, Xu L, Bi Z, Ji S, Bu B
Frontiers in neurology 2023;14:1113404
Frontiers in neurology 2023;14:1113404
Ethyl-acetate fraction from a cinnamon-cortex extract protects pancreatic β-cells from oxidative stress damage.
Li W, Qiao J, Lin K, Sun P, Wang Y, Peng Q, Ye X, Liu W, Sun B
Frontiers in pharmacology 2023;14:1111860
Frontiers in pharmacology 2023;14:1111860
C1QC is a prognostic biomarker with immune-related value in kidney renal clear cell carcinoma.
Yao W, Liu H, Xu F, Cai Z, Hang L, Lu M, Zhao Y, Yang C, Zong Y
Frontiers in genetics 2023;14:1109991
Frontiers in genetics 2023;14:1109991
Prognostic value of autophagy-related genes based on single-cell RNA-sequencing in colorectal cancer.
Luo Y, Deng X, Liao W, Huang Y, Lu C
Frontiers in genetics 2023;14:1109683
Frontiers in genetics 2023;14:1109683
GPR30-mediated non-classic estrogen pathway in mast cells participates in endometriosis pain via the production of FGF2.
Xu X, Wang J, Guo X, Chen Y, Ding S, Zou G, Zhu L, Li T, Zhang X
Frontiers in immunology 2023;14:1106771
Frontiers in immunology 2023;14:1106771
Aqueous extract of Amydrium sinense (Engl.) H. Li alleviates hepatic fibrosis by suppressing hepatic stellate cell activation through inhibiting Stat3 signaling.
Li J, Wu B, Zeng L, Lin Y, Chen Q, Wang H, An L, Zhang J, Chen S, Huang J, Zhan R, Zhang G
Frontiers in pharmacology 2023;14:1101703
Frontiers in pharmacology 2023;14:1101703
Lanatoside C decelerates proliferation and induces apoptosis through inhibition of STAT3 and ROS-mediated mitochondrial membrane potential transformation in cholangiocarcinoma.
Zhang C, Yang HY, Gao L, Bai MZ, Fu WK, Huang CF, Mi NN, Ma HD, Lu YW, Jiang NZ, Tian L, Cai T, Lin YY, Zheng XX, Gao K, Chen JJ, Meng WB
Frontiers in pharmacology 2023;14:1098915
Frontiers in pharmacology 2023;14:1098915
Identification of gene signatures associated with ulcerative colitis and the association with immune infiltrates in colon cancer.
Pan Z, Lin H, Fu Y, Zeng F, Gu F, Niu G, Fang J, Gu B
Frontiers in immunology 2023;14:1086898
Frontiers in immunology 2023;14:1086898
Chitosan oligosaccharide improves ovarian granulosa cells inflammation and oxidative stress in patients with polycystic ovary syndrome.
Xie Q, Hong W, Li Y, Ling S, Zhou Z, Dai Y, Wu W, Weng R, Zhong Z, Tan J, Zheng Y
Frontiers in immunology 2023;14:1086232
Frontiers in immunology 2023;14:1086232
Reward enhances resilience to chronic social defeat stress in mice: Neural ECs and mGluR5 mechanism via neuroprotection in VTA and DRN.
Shi P, Hu L, Ren H, Dai Q
Frontiers in psychiatry 2023;14:1084367
Frontiers in psychiatry 2023;14:1084367
Exploring the molecular mechanism of Gan Shuang granules for the treatment of non-alcoholic steatohepatitis using network pharmacology, molecular docking, and experimental verification.
Zhi G, Shao B, Zheng T, Mu J, Li J, Feng Y, Zhu S, Dang Y, Liu F, Wang D
Frontiers in pharmacology 2023;14:1082451
Frontiers in pharmacology 2023;14:1082451
Exercise training-attenuated insulin resistance and liver injury in elderly pre-diabetic patients correlates with NLRP3 inflammasome.
Zhang T, Tian J, Fan J, Liu X, Wang R
Frontiers in immunology 2023;14:1082050
Frontiers in immunology 2023;14:1082050
Cinobufacini injection suppresses the proliferation of human osteosarcoma cells by inhibiting PIN1-YAP/TAZ signaling pathway.
Chen Y, Wang Y, Zhai Y, Yuan Y, Wang J, Jin Y, Dang L, Song L, Chen C, Wang Y
Frontiers in pharmacology 2023;14:1081363
Frontiers in pharmacology 2023;14:1081363
Orf virus DNA prime-protein boost strategy is superior to adenovirus-based vaccination in mice and sheep.
Wang Y, Sun S, Zhao K, Du L, Wang X, He W, Gao F, Song D, Guan J
Frontiers in immunology 2023;14:1077938
Frontiers in immunology 2023;14:1077938
Chronic intermittent hypobaric hypoxia ameliorates osteoporosis after spinal cord injury through balancing osteoblast and osteoclast activities in rats.
Zhang L, Yin Y, Guo J, Jin L, Hou Z
Frontiers in endocrinology 2023;14:1035186
Frontiers in endocrinology 2023;14:1035186
The prognostic value of the GPAT/AGPAT gene family in hepatocellular carcinoma and its role in the tumor immune microenvironment.
Wen P, Wang R, Xing Y, Ouyang W, Yuan Y, Zhang S, Liu Y, Peng Z
Frontiers in immunology 2023;14:1026669
Frontiers in immunology 2023;14:1026669
Incorporation of a TGF-β2-inhibiting oligodeoxynucleotide molecular adjuvant into a tumor cell lysate vaccine to enhance antiglioma immunity in mice.
Tu L, Wang Z, Yang L, Sun X, Yao Y, Zhang P, Zhang X, Wang L, Yu Y, Yang M
Frontiers in immunology 2023;14:1013342
Frontiers in immunology 2023;14:1013342
PF-429242 exhibits anticancer activity in hepatocellular carcinoma cells via FOXO1-dependent autophagic cell death and IGFBP1-dependent anti-survival signaling.
Lin JC, Liu TP, Chen YB, Yang PM
American journal of cancer research 2023;13(9):4125-4144
American journal of cancer research 2023;13(9):4125-4144
Bioinformatics analysis and experimental validation identified HMGA2/microRNA-200c-3p/LSAMP/Wnt axis as an immunological factor of patients with colorectal cancer.
Xu X, Gong C, Wang Y, Yin Z, Wang X, Hu Y, Fang Z
American journal of cancer research 2023;13(9):3898-3920
American journal of cancer research 2023;13(9):3898-3920
Carcinogen-induced super-enhancer RNA promotes nasopharyngeal carcinoma metastasis through NPM1/c-Myc/NDRG1 axis.
Jia Q, Deng H, Wu Y, He Y, Tang F
American journal of cancer research 2023;13(8):3781-3798
American journal of cancer research 2023;13(8):3781-3798
Yin Yang 1 suppresses tumor invasion and metastasis in nasopharyngeal carcinoma by negatively regulating eIF4E transcriptional activity and expression.
Li M, Duan Y, Wei J, Chen S, Xue C, Zheng L, Deng H, Fan S, Xiong W, Li G, Tan M, Tang F, She K, Zhou M
American journal of cancer research 2023;13(8):3763-3780
American journal of cancer research 2023;13(8):3763-3780
hsa_circ_0000519 promotes the progression of lung adenocarcinoma through the hsa-miR-1296-5p/DARS axis.
Tu G, Peng W, Peng X, Zhao Z, Shi S, Cai Q, He B, Yin W, Peng S, Wang L, Yu F, Wang X
American journal of cancer research 2023;13(8):3342-3367
American journal of cancer research 2023;13(8):3342-3367
Mettl3 synergistically regulates TGF-β/SMAD2/3 to promote proliferation and metastasis of gastric cancer.
Yuan XN, Liu Q, Shao YC, Guan XQ, Yang ZL, Chu MF, Zhang JW, Tian YH, Wei L
American journal of cancer research 2023;13(7):3185-3202
American journal of cancer research 2023;13(7):3185-3202
HSP105 suppresses the progression of cutaneous squamous cell carcinoma by activating the P53 signaling pathway.
Jia M, Zhou KY, Deng LJ, Fang S
American journal of cancer research 2023;13(7):3013-3026
American journal of cancer research 2023;13(7):3013-3026
Lactate-mediated Fascin protrusions promote cell adhesion and migration in cervical cancer.
Han X, Du S, Chen X, Min X, Dong Z, Wang Y, Zhu C, Wei F, Gao S, Cai Q
Theranostics 2023;13(7):2368-2383
Theranostics 2023;13(7):2368-2383
Gαi1/3 mediate Netrin-1-CD146-activated signaling and angiogenesis.
Li Y, Chai JL, Shi X, Feng Y, Li JJ, Zhou LN, Cao C, Li KR
Theranostics 2023;13(7):2319-2336
Theranostics 2023;13(7):2319-2336
Tumor-derived Immunoglobulin-like transcript 4 facilitates angiogenesis of colorectal cancer.
Liu J, Zhang F, He J, Wang S, Wang L, Li J, Shi W, Han Y, Gao A, Sun Y
American journal of cancer research 2023;13(2):419-435
American journal of cancer research 2023;13(2):419-435
FN1 mRNA 3'-UTR supersedes traditional fibronectin 1 in facilitating the invasion and metastasis of gastric cancer through the FN1 3'-UTR-let-7i-5p-THBS1 axis.
Pan S, Zhu J, Liu P, Wei Q, Zhang S, An W, Tong Y, Cheng Z, Liu F
Theranostics 2023;13(14):5130-5150
Theranostics 2023;13(14):5130-5150
Targeted elimination of senescent cells by engineered extracellular vesicles attenuates atherosclerosis in ApoE(-/-) mice with minimal side effects.
Zhang L, Wang C, Hu W, Bu T, Sun W, Zhou T, Qiu S, Wei M, Xing H, Li Z, Yang G, Yuan L
Theranostics 2023;13(14):5114-5129
Theranostics 2023;13(14):5114-5129
Exosomal transfer leads to chemoresistance through oxidative phosphorylation-mediated stemness phenotype in colorectal cancer.
Deng J, Pan T, Lv C, Cao L, Li L, Zhou X, Li G, Li H, Vicencio JM, Xu Y, Wei F, Wang Y, Liu Z, Zhou G, Yin M
Theranostics 2023;13(14):5057-5074
Theranostics 2023;13(14):5057-5074
Application of Lung-Targeted Lipid Nanoparticle-delivered mRNA of soluble PD-L1 via SORT Technology in Acute Respiratory Distress Syndrome.
Sun H, Zhang Y, Wang J, Su J, Zhou D, Yu X, Xu Y, Yang W
Theranostics 2023;13(14):4974-4992
Theranostics 2023;13(14):4974-4992
E3 ubiquitin ligase TRIM21 targets TIF1γ to regulate β-catenin signaling in glioblastoma.
Li Y, Bao L, Zheng H, Geng M, Chen T, Dai X, Xiao H, Yang L, Mao C, Qiu Y, Xu Y, Wang D, Li MX, Chen Q
Theranostics 2023;13(14):4919-4935
Theranostics 2023;13(14):4919-4935
TRPM2 protects against cisplatin-induced acute kidney injury and mitochondrial dysfunction via modulating autophagy.
Yu B, Jin L, Yao X, Zhang Y, Zhang G, Wang F, Su X, Fang Q, Xiao L, Yang Y, Jiang LH, Chen J, Yang W, Lin W, Han F
Theranostics 2023;13(13):4356-4375
Theranostics 2023;13(13):4356-4375
GPX3 expression was down-regulated but positively correlated with poor outcome in human cancers.
Hu Q, Chen J, Yang W, Xu M, Zhou J, Tan J, Huang T
Frontiers in oncology 2023;13:990551
Frontiers in oncology 2023;13:990551
Red recombination enables a wide variety of markerless manipulation of porcine epidemic diarrhea virus genome to generate recombinant virus.
Pan S, Mou C, Chen Z
Frontiers in cellular and infection microbiology 2023;13:1338740
Frontiers in cellular and infection microbiology 2023;13:1338740
Tripterygium glycosides sensitizes cisplatin chemotherapeutic potency by modulating gut microbiota in epithelial ovarian cancer.
Zhan X, Zuo Q, Huang G, Qi Z, Wang Y, Zhu S, Zhong Y, Xiong Y, Chen T, Tan B
Frontiers in cellular and infection microbiology 2023;13:1236272
Frontiers in cellular and infection microbiology 2023;13:1236272
Mechanism of action of icaritin on uterine corpus endometrial carcinoma based on network pharmacology and experimental evaluation.
Jin YB, Liang XC, Cai JH, Wang K, Wang CY, Wang WH, Chen XL, Bao S
Frontiers in oncology 2023;13:1205604
Frontiers in oncology 2023;13:1205604
Tocilizumab (monoclonal anti-IL-6R antibody) reverses anlotinib resistance in osteosarcoma.
Xu J, Chen C, Sun K, Shi Q, Wang B, Huang Y, Ren T, Tang X
Frontiers in oncology 2023;13:1192472
Frontiers in oncology 2023;13:1192472
Determining the mechanism of pulsatilla decoction for treating gastric cancer: a network pharmacology-based study.
Huang S, Qu M, Chen X, Yu S, Kong F
Frontiers in oncology 2023;13:1174848
Frontiers in oncology 2023;13:1174848
The deubiquitinating enzyme MINDY2 promotes pancreatic cancer proliferation and metastasis by stabilizing ACTN4 expression and activating the PI3K/AKT/mTOR signaling pathway.
Liu P, Liu S, Zhu C, Li Y, Li Y, Fei X, Hou J, Wang X, Pan Y
Frontiers in oncology 2023;13:1169833
Frontiers in oncology 2023;13:1169833
PFDN2 promotes cell cycle progression via the hnRNPD-MYBL2 axis in gastric cancer.
He Q, Ding Z, Chen T, Wu H, Song J, Xiang Z, Yang C, Wang S, Xiong B
Frontiers in oncology 2023;13:1164070
Frontiers in oncology 2023;13:1164070
Identification of novel molecular subtypes and a signature to predict prognosis and therapeutic response based on cuproptosis-related genes in prostate cancer.
Zhang J, Jiang S, Gu D, Zhang W, Shen X, Qu M, Yang C, Wang Y, Gao X
Frontiers in oncology 2023;13:1162653
Frontiers in oncology 2023;13:1162653
The role of BHLHE40 in clinical features and prognosis value of PDAC by comprehensive analysis and in vitro validation.
Liu C, Du J, Zheng J, Zhang R, Zhu J, Xing B, Dong L, Zhou Q, Yao X, Gao S, Wang Y, Ren Y, Zhou X
Frontiers in oncology 2023;13:1151321
Frontiers in oncology 2023;13:1151321
Identification and validation of m6A-GPI signatures as a novel prognostic model for colorectal cancer.
Ma B, Bao S, Li Y
Frontiers in oncology 2023;13:1145753
Frontiers in oncology 2023;13:1145753
Schistosoma japonicum-derived peptide SJMHE1 ameliorates allergic symptoms and responses in mice with allergic rhinitis.
Gao X, Mao C, Zheng T, Xu X, Luo X, Zhang S, Liu J, Wang X, Chen X, Dong L
Frontiers in cellular and infection microbiology 2023;13:1143950
Frontiers in cellular and infection microbiology 2023;13:1143950
Identification and verification of the temozolomide resistance feature gene DACH1 in gliomas.
Gu Q, Li L, Yao J, Dong FY, Gan Y, Zhou S, Wang X, Wang XF
Frontiers in oncology 2023;13:1120103
Frontiers in oncology 2023;13:1120103
Notch4 participates in mesenchymal stem cell-induced differentiation in 3D-printed matrix and is implicated in eccrine sweat gland morphogenesis.
Wang Y, Zhang F, Yao B, Hou L, Li Z, Song W, Kong Y, Tan Y, Fu X, Huang S
Burns & trauma 2023;11:tkad032
Burns & trauma 2023;11:tkad032
Identification and validation of prognostic and tumor microenvironment characteristics of necroptosis index and BIRC3 in clear cell renal cell carcinoma.
Wei K, Zhang X, Yang D
PeerJ 2023;11:e16643
PeerJ 2023;11:e16643
Head and neck squamous cell carcinoma-specific prognostic signature and drug sensitive subtypes based on programmed cell death-related genes.
Xu C, Xu H, Liu B
PeerJ 2023;11:e16364
PeerJ 2023;11:e16364
RBM25 binds to and regulates alternative splicing levels of Slc38a9, Csf1, and Coro6 to affect immune and inflammatory processes in H9c2 cells.
Tian X, Zhou G, Li H, Zhang X, Zhao L, Zhang K, Wang L, Liu M, Liu C, Yang P
PeerJ 2023;11:e16312
PeerJ 2023;11:e16312
YAP1 affects the prognosis through the regulation of stemness in endometrial cancer.
Kong W, Huang Y, Jiang P, Tu Y, Li N, Wang J, Zhou Q, Zheng Y, Gou S, Tian C, Yuan R
PeerJ 2023;11:e15891
PeerJ 2023;11:e15891
EXOSC10 is a novel hepatocellular carcinoma prognostic biomarker: a comprehensive bioinformatics analysis and experiment verification.
Meng ZY, Fan YC, Zhang CS, Zhang LL, Wu T, Nong MY, Wang T, Chen C, Jiang LH
PeerJ 2023;11:e15860
PeerJ 2023;11:e15860
RNA N6-methyladenosine reader IGF2BP3 promotes acute myeloid leukemia progression by controlling stabilization of EPOR mRNA.
Fan J, Zhuang M, Fan W, Hou M
PeerJ 2023;11:e15706
PeerJ 2023;11:e15706
Adrenal SGLT1 or SGLT2 as predictors of atherosclerosis under chronic stress based on a computer algorithm.
Li J, Meng L, Wu D, Xu H, Hu X, Hu G, Chen Y, Xu J, Gong T, Liu D
PeerJ 2023;11:e15647
PeerJ 2023;11:e15647
Bone marrow mesenchymal stem cell-derived exosomes protect podocytes from HBx-induced ferroptosis.
Yang X, Yu Y, Li B, Chen Y, Feng M, Hu Y, Jiang W
PeerJ 2023;11:e15314
PeerJ 2023;11:e15314
Transcriptomics reveals the effects of NTRK1 on endoplasmic reticulum stress response-associated genes in human neuronal cell lines.
Jiao B, Zhang M, Zhang C, Cao X, Liu B, Li N, Sun J, Zhang X
PeerJ 2023;11:e15219
PeerJ 2023;11:e15219
Sterol regulatory element binding transcription factor 1 promotes proliferation and migration in head and neck squamous cell carcinoma.
Tan M, Lin X, Chen H, Ye W, Yi J, Li C, Liu J, Su J
PeerJ 2023;11:e15203
PeerJ 2023;11:e15203
METTL3-mediated m6A modification of has_circ_0007905 promotes age-related cataract progression through miR-6749-3p/EIF4EBP1.
Li R, Zhu H, Li Q, Tang J, Jin Y, Cui H
PeerJ 2023;11:e14863
PeerJ 2023;11:e14863
Antimicrobial peptide-modified AIE visual composite wound dressing for promoting rapid healing of infected wounds.
Chen Y, Qian H, Peng D, Jiang Y, Liu Q, Tan Y, Feng L, Cheng B, Li G
Frontiers in bioengineering and biotechnology 2023;11:1338172
Frontiers in bioengineering and biotechnology 2023;11:1338172
S-propargyl-cysteine promotes the stability of atherosclerotic plaque via maintaining vascular muscle contractile phenotype.
Ping L, Zhi-Ming L, Bi-Shan Z, Lei Z, Bo Y, Yi-Chun Z, Ming-Jie W
Frontiers in cell and developmental biology 2023;11:1291170
Frontiers in cell and developmental biology 2023;11:1291170
Chlorpromazine affects autophagy in association with altered Rag GTPase-mTORC1-TFEB signaling.
Li N, Rao L, Zhao X, Shen J, Su D, Ma G, Sun S, Ma Q, Zhang L, Dong C, Tam KY, Prehn JHM, Wang H, Ying Z
Frontiers in cell and developmental biology 2023;11:1266198
Frontiers in cell and developmental biology 2023;11:1266198
Tanshinone IIA inhibits cardiomyocyte pyroptosis through TLR4/NF-κB p65 pathway after acute myocardial infarction.
Chai R, Ye Z, Xue W, Shi S, Wei Y, Hu Y, Wu H
Frontiers in cell and developmental biology 2023;11:1252942
Frontiers in cell and developmental biology 2023;11:1252942
Novel mutations in PLCZ1 lead to early embryonic arrest as a male factor.
Lin Y, Huang Y, Li B, Zhang T, Niu Y, Hu S, Ding Y, Yao G, Wei Z, Yao N, Yao Y, Lu Y, He Y, Zhu Q, Zhang L, Sun Y
Frontiers in cell and developmental biology 2023;11:1193248
Frontiers in cell and developmental biology 2023;11:1193248
The interplay of common genetic variants NRG1 rs2439302 and RET rs2435357 increases the risk of developing Hirschsprung's disease.
Chi S, Li S, Cao G, Guo J, Han Y, Zhou Y, Zhang X, Li Y, Luo Z, Li X, Rong L, Zhang M, Li L, Tang S
Frontiers in cell and developmental biology 2023;11:1184799
Frontiers in cell and developmental biology 2023;11:1184799
Comprehensive analysis of prognostic value, immune implication and biological function of CPNE1 in clear cell renal cell carcinoma.
Zhou H, He Y, Huang Y, Li R, Zhang H, Xia X, Xiong H
Frontiers in cell and developmental biology 2023;11:1157269
Frontiers in cell and developmental biology 2023;11:1157269
Recombinant humanized collagen remodels endometrial immune microenvironment of chronic endometritis through macrophage immunomodulation.
You S, Zhu Y, Li H, He F, Liu S, Yang X, Wang L, Zeng H, Dai J, Hu L
Regenerative biomaterials 2023;10:rbad033
Regenerative biomaterials 2023;10:rbad033
Construction of shared gene signature between rheumatoid arthritis and lung adenocarcinoma helps to predict the prognosis and tumor microenvironment of the LUAD patients.
Shi L, Zou H, Yi J
Frontiers in molecular biosciences 2023;10:1314753
Frontiers in molecular biosciences 2023;10:1314753
Effect of Wu Zhi San supplementation in LPS-induced intestinal inflammation and barrier damage in broilers.
Sun H, Zheng X, Yang B, Yan M, Wang H, Yang S, Shi D, Guo S, Liu C
Frontiers in veterinary science 2023;10:1234769
Frontiers in veterinary science 2023;10:1234769
The identification of hub-methylated differentially expressed genes in osteoarthritis patients is based on epigenomic and transcriptomic data.
Chu ZC, Cong T, Zhao JY, Zhang J, Lou ZY, Gao Y, Tang X
Frontiers in medicine 2023;10:1219830
Frontiers in medicine 2023;10:1219830
The H protein of attenuated canine distemper virus is degraded via endoplasmic reticulum-associated protein degradation.
Wang W, Bi Z, Liu Y, Xia X, Qian J, Tan Y, Zhao J, Song S
Frontiers in veterinary science 2023;10:1214318
Frontiers in veterinary science 2023;10:1214318
Regulation of cellular contractile force, shape and migration of fibroblasts by oncogenes and Histone deacetylase 6.
López-Guajardo A, Zafar A, Al Hennawi K, Rossi V, Alrwaili A, Medcalf JD, Dunning M, Nordgren N, Pettersson T, Estabrook ID, Hawkins RJ, Gad AKB
Frontiers in molecular biosciences 2023;10:1197814
Frontiers in molecular biosciences 2023;10:1197814
ALKBH5 inhibitors as a potential treatment strategy in heart failure-inferences from gene expression profiling.
Komal S, Gohar A, Althobaiti S, Ahmad Khan I, Cui LG, Zhang LR, Han SN, Shakeel M
Frontiers in cardiovascular medicine 2023;10:1194311
Frontiers in cardiovascular medicine 2023;10:1194311
Optimal treatment for post-MI heart failure in rats: dapagliflozin first, adding sacubitril-valsartan 2 weeks later.
Tao W, Yang X, Zhang Q, Bi S, Yao Z
Frontiers in cardiovascular medicine 2023;10:1181473
Frontiers in cardiovascular medicine 2023;10:1181473
Comprehensive analysis to construct a novel immune-related prognostic panel in aging-related gastric cancer based on the lncRNA‒miRNA-mRNA ceRNA network.
Deng C, Peng J, Yuan C, Li H, Li W, Chu H, Wei H, He Y, Zeng L, Huo M, Zhang C
Frontiers in molecular biosciences 2023;10:1163977
Frontiers in molecular biosciences 2023;10:1163977
Effect of blood flow-restricted resistance training on myocardial fibrosis in early spontaneously hypertensive rats.
Tan Z, Chen P, Zheng Y, Pan Y, Wang B, Zhao Y
Frontiers in cardiovascular medicine 2023;10:1101748
Frontiers in cardiovascular medicine 2023;10:1101748
Angong niuhuang wan attenuates LPS-induced acute lung injury by inhibiting PIK3CG/p65/MMP9 signaling in mice based on proteomics.
Li S, Hou J, Wang Q, Liu M, Xu X, Yang H, Li X
Heliyon 2023 Sep;9(9):e20149
Heliyon 2023 Sep;9(9):e20149
Mir-142-5p inhibits the osteogenic differentiation of bone marrow mesenchymal stem cells by targeting Lhx8.
Du Y, Zhong H, Yu C, Lv Y, Yao Y, Peng Z, Lu S
Heliyon 2023 Sep;9(9):e19878
Heliyon 2023 Sep;9(9):e19878
The m6A reader YTHDC1-mediated lncRNA CTBP1-AS2 m6A modification accelerates cholangiocarcinoma progression.
Jin Z, Liu Y
Heliyon 2023 Sep;9(9):e19816
Heliyon 2023 Sep;9(9):e19816
TESC promotes differentiated thyroid cancer development by activating ERK and weakening NIS and radioiodine uptake.
Guo Y, Cai Y, Song F, Zhu L, Hu Y, Liu Y, Ma W, Ge J, Zeng Q, Ding L, Li L, Zheng G, Ge M
Endocrine 2023 Sep;81(3):503-512
Endocrine 2023 Sep;81(3):503-512
Protective effect of Platycodon grandiflorus polysaccharide on apoptosis and mitochondrial damage induced by pseudorabies virus in PK-15 cells.
Xing Y, Cui Y, Xu G, Qi C, Zhang M, Cheng G, Liu Y, Liu J
Cell biochemistry and biophysics 2023 Sep;81(3):493-502
Cell biochemistry and biophysics 2023 Sep;81(3):493-502
Punicalagin alleviates the hyperproliferation of keratinocytes in psoriasis through inhibiting SKP2 expression.
Tang L, Zhang B, Li G, Zhu Y, Feng B, Su Z, Han W, Huang H, Li Q, Wang M, Chen Y, Liu H, Dai Z, Wu D, Li H, Yang L, Lu Y, Ye Z, Zheng G
Journal of natural medicines 2023 Sep;77(4):712-720
Journal of natural medicines 2023 Sep;77(4):712-720
The RIG-I agonist M8 triggers cell death and natural killer cell activation in human papillomavirus-associated cancer and potentiates cisplatin cytotoxicity.
Girone C, Calati F, Lo Cigno I, Salvi V, Tassinari V, Schioppa T, Borgogna C, Lospinoso Severini L, Hiscott J, Cerboni C, Soriani A, Bosisio D, Gariglio M
Cancer immunology, immunotherapy : CII 2023 Sep;72(9):3097-3110
Cancer immunology, immunotherapy : CII 2023 Sep;72(9):3097-3110
Generation of a homozygous RANGRF knockout hiPSC line by CRISPR/Cas9 system.
Jiang M, Tang C, Luo X, Zhou X, Chen M, Chi Y, Lai L, Zou Q
Stem cell research 2023 Sep;71:103136
Stem cell research 2023 Sep;71:103136
The Clinical Characteristics and Potential Molecular Mechanism of LMNA Mutation-Related Lipodystrophy.
Xiao C, Liu J, Yang C, Zhai X, Liu P, Xiao X, Yu M
Advanced biology 2023 Sep;7(9):e2200301
Advanced biology 2023 Sep;7(9):e2200301
Dietary Apigenin Relieves Body Weight and Glycolipid Metabolic Disturbance via Pro-Browning of White Adipose Mediated by Autophagy Inhibition.
Xiong S, Yu S, Wang K, Xiong X, Xia M, Zeng G, Huang Q
Molecular nutrition & food research 2023 Sep;67(18):e2200763
Molecular nutrition & food research 2023 Sep;67(18):e2200763
Lactate Improves Long-term Cognitive Impairment Induced By Repeated Neonatal Sevoflurane Exposures Through SIRT1-mediated Regulation of Adult Hippocampal Neurogenesis and Synaptic Plasticity in Male Mice.
Qiu LL, Tan XX, Yang JJ, Ji MH, Zhang H, Zhao C, Xia JY, Sun J
Molecular neurobiology 2023 Sep;60(9):5273-5291
Molecular neurobiology 2023 Sep;60(9):5273-5291
IRAK-M Ablation Promotes Status Epilepticus-Induced Neuroinflammation via Activating M1 Microglia and Impairing Excitatory Synaptic Function.
Liang XS, Qian TL, Xiong YF, Liang XT, Ding YW, Zhu XY, Li YL, Zhou JL, Tan LY, Li WP, Xie W
Molecular neurobiology 2023 Sep;60(9):5199-5213
Molecular neurobiology 2023 Sep;60(9):5199-5213
Orally Induced High Serum Level of Trimethylamine N-oxide Worsened Glial Reaction and Neuroinflammation on MPTP-Induced Acute Parkinson's Disease Model Mice.
Qiao CM, Quan W, Zhou Y, Niu GY, Hong H, Wu J, Zhao LP, Li T, Cui C, Zhao WJ, Shen YQ
Molecular neurobiology 2023 Sep;60(9):5137-5154
Molecular neurobiology 2023 Sep;60(9):5137-5154
ACE2-EGFR-MAPK signaling contributes to SARS-CoV-2 infection.
Engler M, Albers D, Von Maltitz P, Groß R, Münch J, Cirstea IC
Life science alliance 2023 Sep;6(9)
Life science alliance 2023 Sep;6(9)
Platelet factor 4 (PF4) induces cluster of differentiation 40 (CD40) expression in human aortic endothelial cells (HAECs) through the SIRT1/NF-κB/p65 signaling pathway.
Zhong M, Wang XH, Zhao Y
In vitro cellular & developmental biology. Animal 2023 Sep;59(8):624-635
In vitro cellular & developmental biology. Animal 2023 Sep;59(8):624-635
Inhibition of USP10 induces myeloma cell apoptosis by promoting cyclin D3 degradation.
Xu YJ, Zeng K, Ren Y, Mao CY, Ye YH, Zhu XT, Sun ZY, Cao BY, Zhang ZB, Xu GQ, Huang ZQ, Mao XL
Acta pharmacologica Sinica 2023 Sep;44(9):1920-1931
Acta pharmacologica Sinica 2023 Sep;44(9):1920-1931
FBXO28 suppresses liver cancer invasion and metastasis by promoting PKA-dependent SNAI2 degradation.
Qiao X, Lin J, Shen J, Chen Y, Zheng L, Ren H, Zhao X, Yang H, Li P, Wang Z
Oncogene 2023 Sep;42(39):2878-2891
Oncogene 2023 Sep;42(39):2878-2891
Klotho-beta attenuates Rab8a-mediated exosome regulation and promotes prostate cancer progression.
Wu T, Zhang Y, Han Q, Lu X, Cheng Y, Chen J, Sha J, Xia W
Oncogene 2023 Sep;42(38):2801-2815
Oncogene 2023 Sep;42(38):2801-2815
Cytological and functional effect of complement 3a on Human Scleral Fibroblasts.
Xiao K, Jie Y, Luo M, Long Q
Cutaneous and ocular toxicology 2023 Sep;42(3):137-143
Cutaneous and ocular toxicology 2023 Sep;42(3):137-143
MIR663AHG as a competitive endogenous RNA regulating TGF-β-induced epithelial proliferation and epithelial-mesenchymal transition in benign prostate hyperplasia.
Tong S, Mo M, Hu X, Wu L, Chen M, Zhao C
Journal of biochemical and molecular toxicology 2023 Sep;37(9):e23391
Journal of biochemical and molecular toxicology 2023 Sep;37(9):e23391
Cuproptosis enhances docetaxel chemosensitivity by inhibiting autophagy via the DLAT/mTOR pathway in prostate cancer.
Wen H, Qu C, Wang Z, Gao H, Liu W, Wang H, Sun H, Gu J, Yang Z, Wang X
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Sep;37(9):e23145
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Sep;37(9):e23145
ASXL3 gene mutations inhibit cell proliferation and promote cell apoptosis in mouse cardiomyocytes by upregulating lncRNA NONMMUT063967.2.
Liu Z, Jiang Y, Fang F, Li R, Han J, Yang X, Deng Q, Li LS, Lei TY, Li DZ, Liao C
Biochemistry and biophysics reports 2023 Sep;35:101505
Biochemistry and biophysics reports 2023 Sep;35:101505
Lysine methylation of PPP1CA by the methyltransferase SUV39H2 disrupts TFEB-dependent autophagy and promotes intervertebral disc degeneration.
Liang H, Luo R, Li G, Zhang W, Zhu D, Wu D, Zhou X, Tong B, Wang B, Feng X, Wang K, Song Y, Yang C
Cell death and differentiation 2023 Sep;30(9):2135-2150
Cell death and differentiation 2023 Sep;30(9):2135-2150
ANRIL promotes the regulation of colorectal cancer on lymphatic endothelial cells via VEGF-C and is the key target for Pien Tze Huang to inhibit cancer metastasis.
Huang B, Lu Y, Ni Z, Liu J, He Y, An H, Ye F, Shen J, Lin M, Chen Y, Lin J
Cancer gene therapy 2023 Sep;30(9):1260-1273
Cancer gene therapy 2023 Sep;30(9):1260-1273
Saikosaponin A protects against uremic toxin indole‑3 acetic acid‑induced damage to the myocardium.
Chen C, Hu X, Chen X
Molecular medicine reports 2023 Sep;28(3)
Molecular medicine reports 2023 Sep;28(3)
Hirudin inhibits glioma growth through mTOR-regulated autophagy.
Ma Y, Wu S, Zhao F, Li H, Li Q, Zhang J, Li H, Yuan Z
Journal of cellular and molecular medicine 2023 Sep;27(18):2701-2713
Journal of cellular and molecular medicine 2023 Sep;27(18):2701-2713
Loss of NSUN6 inhibits osteosarcoma progression by downregulating EEF1A2 expression and activation of Akt/mTOR signaling pathway via m(5)C methylation.
Hu S, Yang M, Xiao K, Yang Z, Cai L, Xie Y, Wang L, Wei R
Experimental and therapeutic medicine 2023 Sep;26(3):457
Experimental and therapeutic medicine 2023 Sep;26(3):457
Trans-ε-viniferin as an inhibitor of TMEM16A preventing intestinal smooth muscle contraction.
Liu XY, Zhao Y, Jin LL, Pang Y, Yu B
Journal of Asian natural products research 2023 Sep;25(9):867-879
Journal of Asian natural products research 2023 Sep;25(9):867-879
HDAC6 decreases H4K16 and α-tubulin acetylation during porcine oocyte maturation.
Zhang S, Sui L, Kong X, Huang R, Li Z
Cell cycle (Georgetown, Tex.) 2023 Sep;22(18):2057-2069
Cell cycle (Georgetown, Tex.) 2023 Sep;22(18):2057-2069
Structure and anti-inflammatory activity of neo-clerodane diterpenoids from Scutellaria barbata.
Li S, Xu D, Jia J, Zou W, Liu J, Wang Y, Zhang K, Zheng X, Ma YY, Zhang X, Zhao DG
Phytochemistry 2023 Sep;213:113771
Phytochemistry 2023 Sep;213:113771
Elucidation of the mechanism of nuclear localization of Mexican tetra Neu4 via bipartite nuclear localization signal and less conserved regions.
Hyodo T, Honda A, Yamate S, Kubo Y, Komatsu M, Shiozaki K
Biochimie 2023 Sep;212:123-134
Biochimie 2023 Sep;212:123-134
Sulforaphane, an NRF2 agonist, alleviates ferroptosis in acute liver failure by regulating HDAC6 activity.
Zhang YQ, Shi CX, Zhang DM, Zhang LY, Wang LW, Gong ZJ
Journal of integrative medicine 2023 Sep;21(5):464-473
Journal of integrative medicine 2023 Sep;21(5):464-473
Excessive Lysosomal Stress Response and Consequently Impaired Autophagy Contribute to Fluoride-Induced Developmental Neurotoxicity.
Xu W, Hu Z, Tang Y, Zhang J, Xu S, Niu Q
Biological trace element research 2023 Sep;201(9):4472-4483
Biological trace element research 2023 Sep;201(9):4472-4483
Alleviative Effect of Threonine on Cadmium-Induced Liver Injury in Mice.
Fang Z, Li Y, Wang J, Wang X, Huang L, Sun L, Deng Q
Biological trace element research 2023 Sep;201(9):4437-4446
Biological trace element research 2023 Sep;201(9):4437-4446
Fecal Microbiota Transplantation from Aged Mice Render Recipient Mice Resistant to MPTP-Induced Nigrostriatal Degeneration Via a Neurogenesis-Dependent but Inflammation-Independent Manner.
Qiao CM, Zhou Y, Quan W, Ma XY, Zhao LP, Shi Y, Hong H, Wu J, Niu GY, Chen YN, Zhu S, Cui C, Zhao WJ, Shen YQ
Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics 2023 Sep;20(5):1405-1426
Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics 2023 Sep;20(5):1405-1426
Electroacupuncture-Modulated MiR-106b-5p Expression Enhances Autophagy by Targeting Beclin-1 to Promote Motor Function Recovery After Spinal Cord Injury in Rats.
Guo S, Chen J, Yang Y, Li X, Tang Y, Gui Y, Chen J, Xu J
Neurospine 2023 Sep;20(3):1011-1027
Neurospine 2023 Sep;20(3):1011-1027
RBMX involves in telomere stability maintenance by regulating TERRA expression.
Liu J, Zheng T, Chen D, Huang J, Zhao Y, Ma W, Liu H
PLoS genetics 2023 Sep;19(9):e1010937
PLoS genetics 2023 Sep;19(9):e1010937
Phosphorylation of KRT8 (keratin 8) by excessive mechanical load-activated PKN (protein kinase N) impairs autophagosome initiation and contributes to disc degeneration.
Wang D, Shang Q, Mao J, Gao C, Wang J, Wang D, Wang H, Jia H, Peng P, Du M, Luo Z, Yang L
Autophagy 2023 Sep;19(9):2485-2503
Autophagy 2023 Sep;19(9):2485-2503
TRAF1 improves cisplatin-induced acute kidney injury via inhibition of inflammation and metabolic disorders.
Zhang X, Xu Y, Zhang W, Yang B, Zhang Y, Jia Z, Huang S, Zhang A, Li S
Biochimica et biophysica acta. General subjects 2023 Sep;1867(9):130423
Biochimica et biophysica acta. General subjects 2023 Sep;1867(9):130423
TRIM25-mediated ubiquitination of G3BP1 regulates the proliferation and migration of human neuroblastoma cells.
Yang Y, Luo Y, Yang C, Hu R, Qin X, Li C
Biochimica et biophysica acta. Gene regulatory mechanisms 2023 Sep;1866(3):194954
Biochimica et biophysica acta. Gene regulatory mechanisms 2023 Sep;1866(3):194954
The adiponectin receptor agonist AdipoAI attenuates periodontitis in diabetic rats by inhibiting gingival fibroblast-induced macrophage migration.
Qiu W, Wang Z, Chen Z, Sun Q, Wu H, Chen Z, Luan K, Liu Z, Ding D, Tu Q, Chen J, Wu B, Fang F
British journal of pharmacology 2023 Sep;180(18):2436-2451
British journal of pharmacology 2023 Sep;180(18):2436-2451
Aerobic exercise enhances mitochondrial homeostasis to counteract D-galactose-induced sarcopenia in zebrafish.
Chen ZL, Guo C, Zou YY, Feng C, Yang DX, Sun CC, Wen W, Jian ZJ, Zhao Z, Xiao Q, Zheng L, Peng XY, Zhou ZQ, Tang CF
Experimental gerontology 2023 Sep;180:112265
Experimental gerontology 2023 Sep;180:112265
Genetic modification of miR-34a enhances efficacy of transplanted human dental pulp stem cells after ischemic stroke.
Wang J, He P, Tian Q, Luo Y, He Y, Liu C, Gong P, Guo Y, Ye Q, Li M
Neural regeneration research 2023 Sep;18(9):2029-2036
Neural regeneration research 2023 Sep;18(9):2029-2036
miR-181b promotes angiogenesis and neurological function recovery after ischemic stroke.
Xue LX, Shu LY, Wang HM, Lu KL, Huang LG, Xiang JY, Geng Z, Zhao YW, Chen H
Neural regeneration research 2023 Sep;18(9):1983-1989
Neural regeneration research 2023 Sep;18(9):1983-1989
Serum response factor promotes axon regeneration following spinal cord transection injury.
Feng GY, Zhang NL, Liu XW, Tong LX, Zhang CL, Zhou S, Zhang LP, Huang F
Neural regeneration research 2023 Sep;18(9):1956-1960
Neural regeneration research 2023 Sep;18(9):1956-1960
Hexachlorocyclohexane impairs human sperm motility by affecting lysine glutarylation and mitochondrial functions.
Yang L, Mei G, Yang Y, Cui J, Peng S, Peng Z, Cheng Y
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2023 Sep;179:113991
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2023 Sep;179:113991
Mitophagy contributes to zinc-induced ferroptosis in porcine testis cells.
Li Q, Yang Q, Guo P, Feng Y, Wang S, Guo J, Tang Z, Yu W, Liao J
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2023 Sep;179:113950
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2023 Sep;179:113950
The therapeutic effect of Shenhua tablet against mesangial cell proliferation and renal inflammation in mesangial proliferative glomerulonephritis.
He J, Peng F, Chang J, Zhao Y, Qu Y, Liu J, Liu R, Li P, Cai G, Hong Q, Chen X
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Sep;165:115233
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Sep;165:115233
DWL-4-140: A allene small molecule targeting STING that alleviates lupus-like phenotype in Trex1(-/-) mice.
Du H, Kou M, Deng W, Zhou X, Zhang X, Huang Z, Ren B, Cai X, Xu S, Chen Y, Chen L, Chen C, Bao H, Chen Q, Li D
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Sep;165:115188
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Sep;165:115188
Inhibition of autophagy and RIP1/RIP3/MLKL-mediated necroptosis by edaravone attenuates blood spinal cord barrier disruption following spinal cord injury.
Xu B, Fang J, Wang J, Jin X, Liu S, Song K, Wang P, Liu J, Liu S
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Sep;165:115165
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Sep;165:115165
Cardioprotective efficacy of Xin-shu-bao tablet in heart failure with reduced ejection fraction by modulating THBD/ARRB1/FGF1/STIM1 signaling.
Zhang F, Xu X, Hou J, Xiao H, Guo F, Li X, Yang H
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Sep;165:115119
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Sep;165:115119
A novel onco-cardiological mouse model of lung cancer-induced cardiac dysfunction and its application in identifying potential roles of tRNA-derived small RNAs.
Wu Q, Zou S, Liu W, Liang M, Chen Y, Chang J, Liu Y, Yu X
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Sep;165:115117
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Sep;165:115117
Rgl-exomiR-7972, a novel plant exosomal microRNA derived from fresh Rehmanniae Radix, ameliorated lipopolysaccharide-induced acute lung injury and gut dysbiosis.
Qiu FS, Wang JF, Guo MY, Li XJ, Shi CY, Wu F, Zhang HH, Ying HZ, Yu CH
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Sep;165:115007
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Sep;165:115007
Sialic Acid Enhanced the Antistress Capability under Challenging Situations by Increasing Synaptic Transmission.
Huang C, Wang R, Wang Y, Liu H, Chen XT, Gu X, Wang HL
The Journal of nutrition 2023 Sep;153(9):2561-2570
The Journal of nutrition 2023 Sep;153(9):2561-2570
AHR, a novel inhibitory immune checkpoint receptor, is a potential therapeutic target for chemoresistant glioblastoma.
Tan N, Zhao W, Wang Y, Li P, Liu J, Sun Z, Pan J, Song S, Li S, Liu Z, Bian Y
Journal of cancer research and clinical oncology 2023 Sep;149(12):9705-9720
Journal of cancer research and clinical oncology 2023 Sep;149(12):9705-9720
miR-32-5p induces hepatic steatosis and hyperlipidemia by triggering de novo lipogenesis.
Wang YD, Wu LL, Mai YN, Wang K, Tang Y, Wang QY, Li JY, Jiang LY, Liao ZZ, Hu C, Wang YY, Liu JJ, Liu JH, Xiao XH
Metabolism: clinical and experimental 2023 Sep;146:155660
Metabolism: clinical and experimental 2023 Sep;146:155660
Blocking IL-6 signaling improves glucose tolerance via SLC39A5-mediated suppression of glucagon secretion.
Chen W, Cui W, Wu J, Zheng W, Sun X, Zhang J, Shang H, Yuan Y, Li X, Wang J, Hu X, Chen L, Zeng F, Xiao RP, Zhang X
Metabolism: clinical and experimental 2023 Sep;146:155641
Metabolism: clinical and experimental 2023 Sep;146:155641
Targeting the Hedgehog pathway with novel Gli1 hydrophobic tagging degraders.
Li X, Sun R, Wu H, Zheng C, Long YQ
Bioorganic chemistry 2023 Sep;138:106649
Bioorganic chemistry 2023 Sep;138:106649
Predicting and overcoming resistance to CDK9 inhibitors for cancer therapy.
Hu C, Shen L, Zou F, Wu Y, Wang B, Wang A, Wu C, Wang L, Liu J, Wang W, Liu Q
Acta pharmaceutica Sinica. B 2023 Sep;13(9):3694-3707
Acta pharmaceutica Sinica. B 2023 Sep;13(9):3694-3707
UBE3A and MCM6 synergistically regulate the proliferation and migration of lung adenocarcinoma cells.
Luo Y, Yang Y, Yang C, Li C, Hu R, Geng W, Kang X, Lin H
FEBS open bio 2023 Sep;13(9):1756-1771
FEBS open bio 2023 Sep;13(9):1756-1771
Brain-derived estrogen: a critical player in maintaining cognitive health of aged female rats, possibly involving GPR30.
Hu J, Huang Y, Gao F, Sun W, Liu H, Ma H, Yuan T, Liu Z, Tang L, Ma Y, Zhang X, Bai J, Wang R
Neurobiology of aging 2023 Sep;129:15-27
Neurobiology of aging 2023 Sep;129:15-27
Celastrol attenuates diabetic nephropathy by upregulating SIRT1-mediated inhibition of EZH2related wnt/β-catenin signaling.
Tang Y, Wan F, Tang X, Lin Y, Zhang H, Cao J, Yang R
International immunopharmacology 2023 Sep;122:110584
International immunopharmacology 2023 Sep;122:110584
Liensinine pretreatment reduces inflammation, oxidative stress, apoptosis, and autophagy to alleviate sepsis acute kidney injury.
Zhang W, Chen H, Xu Z, Zhang X, Tan X, He N, Shen J, Dong J
International immunopharmacology 2023 Sep;122:110563
International immunopharmacology 2023 Sep;122:110563
The p65-LOC727924-miR-26a/KPNA3-p65 regulatory loop mediates vasoactive intestinal peptide effects on osteoarthritis chondrocytes.
Li Y, Li H, Wang L, Xie W, Yuan D, Wen Z, Zhang T, Lai J, Xiong Z, Shan Y, Jiang W
International immunopharmacology 2023 Sep;122:110518
International immunopharmacology 2023 Sep;122:110518
Ameliorative effects of the Coptis inflorescence extract against lung injury in diabetic mice by regulating AMPK/NEU1 signaling.
Wang L, Wang J, Ren G, Sun S, Nishikawa K, Yu J, Zhang C
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Sep;118:154963
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Sep;118:154963
Berberine ameliorates iron levels and ferroptosis in the brain of 3 × Tg-AD mice.
Li X, Chen J, Feng W, Wang C, Chen M, Li Y, Chen J, Liu X, Liu Q, Tian J
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Sep;118:154962
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Sep;118:154962
Total alkaloids of Fritillaria unibracteata var. wabuensis bulbus ameliorate chronic asthma via the TRPV1/Ca(2+)/NFAT pathway.
Peng M, Li J, Zhou J, Zhang B, Liao J, Yang D, Wang Y, Yang Y, Li R, Tang X, Lu Q, Zhao Q
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Sep;118:154946
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Sep;118:154946
Gentianella acuta-derived Gen-miR-1 suppresses myocardial fibrosis by targeting HAX1/HMG20A/Smads axis to attenuate inflammation in cardiac fibroblasts.
Zhang T, Zhang Y, Li S, Ge H, Song Q, Zhang Y, Yang G, Li A
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Sep;118:154923
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Sep;118:154923
Comprehensive analysis of transcriptome-wide N6-methyladenosine methylomes in the Barrett's esophagus in rats.
Zou K, Dong H, Li M, Zhang Y, Zhang K, Song D, Chu C
Genomics 2023 Sep;115(5):110687
Genomics 2023 Sep;115(5):110687
Zoledronate Promotes Peri-Implant Osteogenesis in Diabetic Osteoporosis by the AMPK Pathway.
Zhang Y, Jia S, Wen G, Xie S, Song Z, Qi M, Liang Y, Bi W, Dong W
Calcified tissue international 2023 Sep;113(3):329-343
Calcified tissue international 2023 Sep;113(3):329-343
KDM2B regulates inflammation and oxidative stress of sepsis via targeting NF-κB and AP-1 pathways.
Li X, Tian X, Zhang D
Immunity, inflammation and disease 2023 Sep;11(9):e985
Immunity, inflammation and disease 2023 Sep;11(9):e985
FOSL2 participates in renal fibrosis via SGK1-mediated epithelial-mesenchymal transition of proximal tubular epithelial cells.
Liu N, Li D, Liu D, Liu Y, Lei J
Journal of translational internal medicine 2023 Sep;11(3):294-308
Journal of translational internal medicine 2023 Sep;11(3):294-308
CircNCOR1 regulates breast cancer radiotherapy efficacy by regulating CDK2 via hsa-miR-638 binding.
He ZY, Zhuo RG, Yang SP, Zhou P, Xu JY, Zhou J, Wu SG
Cellular signalling 2023 Sep;109:110787
Cellular signalling 2023 Sep;109:110787
Disulfiram suppresses epithelial-mesenchymal transition (EMT), migration and invasion in cervical cancer through the HSP90A/NDRG1 pathway.
Zheng P, Wu Y, Wang Y, Hu F
Cellular signalling 2023 Sep;109:110771
Cellular signalling 2023 Sep;109:110771
ADAR1 polymorphisms contribute to increased susceptibility in pediatric acute lymphoblastic leukemia.
Cai M, Liu X, Luo A, Yang X, Yan Y, Liu S, Wang X, Luo Z, Wu X, Huang K, Yang L, Jiang H, Xu L, Liu X
Annals of hematology 2023 Sep;102(9):2483-2492
Annals of hematology 2023 Sep;102(9):2483-2492
miR-146b-5p promotes duck Tembusu virus replication by targeting RPS14.
Huang J, Lei L, Cui M, Cheng A, Wang M, Liu M, Zhu D, Chen S, Zhao X, Yang Q, Wu Y, Zhang S, Ou X, Mao S, Gao Q, Sun D, Tian B, Yin Z, Jia R
Poultry science 2023 Sep;102(9):102890
Poultry science 2023 Sep;102(9):102890
TP53RK Drives the Progression of Chronic Kidney Disease by Phosphorylating Birc5.
Wu M, Jin Q, Xu X, Fan J, Chen W, Miao M, Gu R, Zhang S, Guo Y, Huang S, Zhang Y, Zhang A, Jia Z
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Sep;10(25):e2301753
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Sep;10(25):e2301753
CSNK2A2 promotes hepatocellular carcinoma progression through activation of NF-κB pathway.
Yang S, Peng LR, Yu AQ, Li J
Annals of hepatology 2023 Sep-Oct;28(5):101118
Annals of hepatology 2023 Sep-Oct;28(5):101118
Infection by exosome-carried Coxsackievirus B3 induces immune escape resulting in an aggravated pathogenesis.
Fu Y, Zi R, Xiong S
Microbes and infection 2023 Sep-Oct;25(7):105148
Microbes and infection 2023 Sep-Oct;25(7):105148
Novel Long Non-Coding RNA (lncRNA) Transcript AL137782.1 Promotes the Migration of Normal Lung Epithelial Cells through Positively Regulating LMO7.
Zhang Y, Wang W, Duan C, Li M, Gao L
International journal of molecular sciences 2023 Sep 9;24(18)
International journal of molecular sciences 2023 Sep 9;24(18)
Vitamin D3 regulates NSUN2 expression and inhibits melanoma cell proliferation and migration.
Wang L, Zhang Q, Wang J, Lu H, Zeng W, Zhang T
Molecular diversity 2023 Sep 9;
Molecular diversity 2023 Sep 9;
SENP5 promotes homologous recombination-mediated DNA damage repair in colorectal cancer cells through H2AZ deSUMOylation.
Liu T, Wang H, Chen Y, Wan Z, Du Z, Shen H, Yu Y, Ma S, Xu Y, Li Z, Yu N, Zhang F, Cao K, Cai J, Zhang W, Gao F, Yang Y
Journal of experimental & clinical cancer research : CR 2023 Sep 8;42(1):234
Journal of experimental & clinical cancer research : CR 2023 Sep 8;42(1):234
Enhanced therapeutic effect of PEDF-loaded mesenchymal stem cell-derived small extracellular vesicles against oxygen-induced retinopathy through increased stability and penetrability of PEDF.
Fan R, Su L, Zhang H, Jiang Y, Yu Z, Zhang X, Li X
Journal of nanobiotechnology 2023 Sep 8;21(1):327
Journal of nanobiotechnology 2023 Sep 8;21(1):327
The DACH1 Gene Transcriptional Activation and Protein Degradation Mediated by Transactivator Tas of Prototype Foamy Virus.
Ma Y, Wei J, Song J, Hu Z, Zhang R, Li Z, Sun Y
Viruses 2023 Sep 8;15(9)
Viruses 2023 Sep 8;15(9)
Gut microbes exacerbate systemic inflammation and behavior disorders in neurologic disease CADASIL.
Liu S, Men X, Guo Y, Cai W, Wu R, Gao R, Zhong W, Guo H, Ruan H, Chou S, Mai J, Ping S, Jiang C, Zhou H, Mou X, Zhao W, Lu Z
Microbiome 2023 Sep 8;11(1):202
Microbiome 2023 Sep 8;11(1):202
Bone marrow mesenchymal stem cellsderived exosomes stabilize atherosclerosis through inhibiting pyroptosis.
Bai Z, Hu H, Hu F, Ji J, Ji Z
BMC cardiovascular disorders 2023 Sep 7;23(1):441
BMC cardiovascular disorders 2023 Sep 7;23(1):441
Mature human induced pluripotent stem cell-derived cardiomyocytes promote angiogenesis through alpha-B crystallin.
Tanaka Y, Kadota S, Zhao J, Kobayashi H, Okano S, Izumi M, Honda Y, Ichimura H, Shiba N, Uemura T, Wada Y, Chuma S, Nakada T, Tohyama S, Fukuda K, Yamada M, Seto T, Kuwahara K, Shiba Y
Stem cell research & therapy 2023 Sep 7;14(1):240
Stem cell research & therapy 2023 Sep 7;14(1):240
PI3K/Akt signalling pathway-associated long noncoding RNA signature predicts the prognosis of laryngeal cancer patients.
Nie Q, Cao H, Yang J, Liu T, Wang B
Scientific reports 2023 Sep 7;13(1):14764
Scientific reports 2023 Sep 7;13(1):14764
Interferon inhibits a model RNA virus via a limited set of inducible effector genes.
McDougal MB, De Maria AM, Ohlson MB, Kumar A, Xing C, Schoggins JW
EMBO reports 2023 Sep 6;24(9):e56901
EMBO reports 2023 Sep 6;24(9):e56901
FBL promotes cancer cell resistance to DNA damage and BRCA1 transcription via YBX1.
Sun X, Gao C, Xu X, Li M, Zhao X, Wang Y, Wang Y, Zhang S, Yan Z, Liu X, Wu C
EMBO reports 2023 Sep 6;24(9):e56230
EMBO reports 2023 Sep 6;24(9):e56230
UBQLN2 and HSP70 participate in Parkin-mediated mitophagy by facilitating outer mitochondrial membrane rupture.
Ma Q, Xin J, Peng Q, Li N, Sun S, Hou H, Ma G, Wang N, Zhang L, Tam KY, Dussmann H, Prehn JH, Wang H, Ying Z
EMBO reports 2023 Sep 6;24(9):e55859
EMBO reports 2023 Sep 6;24(9):e55859
Phosphorylation of PPDPF via IL6-JAK2 activates the Wnt/β-catenin pathway in colorectal cancer.
Zi Y, Liu L, Gao J, Xu X, Guan Y, Rong Z, Cao Z, Li M, Zeng Z, Fan Q, Tang F, He J, Feng D, Chen J, Dai Y, Huang Y, Nie Y, Pei H, Cai Q, Li Z, Sun L, Deng Y
EMBO reports 2023 Sep 6;24(9):e55060
EMBO reports 2023 Sep 6;24(9):e55060
Hyodeoxycholic acid ameliorates nonalcoholic fatty liver disease by inhibiting RAN-mediated PPARα nucleus-cytoplasm shuttling.
Zhong J, He X, Gao X, Liu Q, Zhao Y, Hong Y, Zhu W, Yan J, Li Y, Li Y, Zheng N, Bao Y, Wang H, Ma J, Huang W, Liu Z, Lyu Y, Ke X, Jia W, Xie C, Hu Y, Sheng L, Li H
Nature communications 2023 Sep 6;14(1):5451
Nature communications 2023 Sep 6;14(1):5451
Activation of G-protein-coupled receptor 183 initiates inflammatory pain via macrophage CCL22 secretion.
Qi Z, Zhong W, Jiao B, Chen K, Yang X, Wang L, Zeng W, Huang J, Xie J
European journal of pharmacology 2023 Sep 5;954:175872
European journal of pharmacology 2023 Sep 5;954:175872
Riboflavin ameliorates pathological cardiac hypertrophy and fibrosis through the activation of short-chain acyl-CoA dehydrogenase.
Peng H, Xie M, Zhong X, Su Y, Qin X, Xu Q, Zhou S
European journal of pharmacology 2023 Sep 5;954:175849
European journal of pharmacology 2023 Sep 5;954:175849
A natural chalcone cardamonin inhibits necroptosis and ameliorates dextran sulfate sodium (DSS)-induced colitis by targeting RIPK1/3 kinases.
Shen X, Chen H, Wen T, Liu L, Yang Y, Xie F, Wang L
European journal of pharmacology 2023 Sep 5;954:175840
European journal of pharmacology 2023 Sep 5;954:175840
Activation of TrkB signaling mitigates cerebellar anomalies caused by Rbm4-Bdnf deficiency.
Tsai YY, Shen CL, D D, Tsai CY, Tarn WY
Communications biology 2023 Sep 5;6(1):910
Communications biology 2023 Sep 5;6(1):910
Lactate modulates iron metabolism by binding soluble adenylyl cyclase.
Liu W, Zhang S, Li Q, Wu Y, Jia X, Feng W, Li Z, Shi Y, Hou Q, Ma J, Liu Y, Gao P, Ganz T, Liu S
Cell metabolism 2023 Sep 5;35(9):1597-1612.e6
Cell metabolism 2023 Sep 5;35(9):1597-1612.e6
N6-methyladenosine modification of PLOD2 causes spermatocyte damage in rats with varicocele.
Li H, Zhao J, Deng H, Zhong Y, Chen M, Chi L, Luo G, Cao C, Yu C, Liu H, Zhang X
Cellular & molecular biology letters 2023 Sep 5;28(1):72
Cellular & molecular biology letters 2023 Sep 5;28(1):72
MiR-3653 blocks autophagy to inhibit epithelial-mesenchymal transition in breast cancer cells by targeting the autophagy-regulatory genes ATG12 and AMBRA1.
Song H, Zhao Z, Ma L, Zhang B, Song Y
Chinese medical journal 2023 Sep 5;136(17):2086-2100
Chinese medical journal 2023 Sep 5;136(17):2086-2100
Targeting of AKT1 by miR-143-3p Suppresses Epithelial-to-Mesenchymal Transition in Prostate Cancer.
Armstrong L, Willoughby CE, McKenna DJ
Cells 2023 Sep 5;12(18)
Cells 2023 Sep 5;12(18)
Cystathionine β-Synthase Suppresses NLRP3 Inflammasome Activation via Redox Regulation in Microglia.
Mou YJ, Ma YT, Yuan X, Wang M, Liu Y, Pei CS, Liu CF, Hou XO, Hu LF
Antioxidants & redox signaling 2023 Sep 5;
Antioxidants & redox signaling 2023 Sep 5;
Characterization of a Human Gastrointestinal Stromal Tumor Cell Line Established by SV40LT-Mediated Immortalization.
Hu X, Su P, Liu B, Guo J, Wang Z, He C, Wang Z, Kou Y
International journal of molecular sciences 2023 Sep 4;24(17)
International journal of molecular sciences 2023 Sep 4;24(17)
Curcumin-Loaded Macrophage-Derived Exosomes Effectively Improve Wound Healing.
Li D, Zhang C, Gao Z, Xia N, Wu C, Liu C, Tian H, Mei X
Molecular pharmaceutics 2023 Sep 4;20(9):4453-4467
Molecular pharmaceutics 2023 Sep 4;20(9):4453-4467
Increased DNMT1 Involvement in the Activation of LO2 Cell Death Induced by Silver Nanoparticles via Promoting TFEB-Dependent Autophagy.
Chen J, Zheng D, Cai Z, Zhong B, Zhang H, Pan Z, Ling X, Han Y, Meng J, Li H, Chen X, Zhang H, Liu L
Toxics 2023 Sep 4;11(9)
Toxics 2023 Sep 4;11(9)
Ursolic Acid Alleviates Neuroinflammation after Intracerebral Hemorrhage by Mediating Microglial Pyroptosis via the NF-κB/NLRP3/GSDMD Pathway.
Lei P, Li Z, Hua Q, Song P, Gao L, Zhou L, Cai Q
International journal of molecular sciences 2023 Sep 30;24(19)
International journal of molecular sciences 2023 Sep 30;24(19)
Dihydroorotate dehydrogenase promotes cell proliferation and suppresses cell death in esophageal squamous cell carcinoma and colorectal carcinoma.
Shi ZZ, Jin X, Li WT, Tao H, Song SJ, Fan ZW, Jiang W, Liang JW, Bai J
Translational cancer research 2023 Sep 30;12(9):2294-2307
Translational cancer research 2023 Sep 30;12(9):2294-2307
The histone deacetylase inhibitor SAHA exerts a protective effect against myocardial ischemia/reperfusion injury by inhibiting sodium-calcium exchanger.
Shi X, Yin Y, Guo X, Liu M, Ma F, Tian L, Zheng M, Liu G
Biochemical and biophysical research communications 2023 Sep 3;671:105-115
Biochemical and biophysical research communications 2023 Sep 3;671:105-115
African Swine Fever Virus H240R Protein Inhibits the Production of Type I Interferon through Disrupting the Oligomerization of STING.
Ye G, Liu H, Liu X, Chen W, Li J, Zhao D, Wang G, Feng C, Zhang Z, Zhou Q, Zheng J, Bu Z, Weng C, Huang L
Journal of virology 2023 Sep 28;97(9):e0057723
Journal of virology 2023 Sep 28;97(9):e0057723
Pleckstrin-2 promotes tumour immune escape from NK cells by activating the MT1-MMP-MICA signalling axis in gastric cancer.
Mao D, Zhou Z, Chen H, Liu X, Li D, Chen X, He Y, Liu M, Zhang C
Cancer letters 2023 Sep 28;572:216351
Cancer letters 2023 Sep 28;572:216351
HSP90B1-mediated plasma membrane localization of GLUT1 promotes radioresistance of glioblastomas.
Li Y, Ge Y, Zhao M, Ding F, Wang X, Shi Z, Ge X, Wang X, Qian X
Journal of biomedical research 2023 Sep 28;37(5):326-339
Journal of biomedical research 2023 Sep 28;37(5):326-339
Benzophenanthridine Alkaloid Chelerythrine Elicits Necroptosis of Gastric Cancer Cells via Selective Conjugation at the Redox Hyperreactive C-Terminal Sec(498) Residue of Cytosolic Selenoprotein Thioredoxin Reductase.
Liu M, Sun S, Meng Y, Wang L, Liu H, Shi W, Zhang Q, Xu W, Sun B, Xu J
Molecules (Basel, Switzerland) 2023 Sep 28;28(19)
Molecules (Basel, Switzerland) 2023 Sep 28;28(19)
SQLE Knockdown inhibits bladder cancer progression by regulating the PTEN/AKT/GSK3β signaling pathway through P53.
Zou F, Chen W, Song T, Xing J, Zhang Y, Chen K, Hu W, Li L, Ning J, Li C, Yu W, Cheng F
Cancer cell international 2023 Sep 28;23(1):221
Cancer cell international 2023 Sep 28;23(1):221
Fucogalactan Sulfate (FS) from Laminaria japonica Regulates Lipid Metabolism in Diet-Induced Humanized Dyslipidemia Mice via an Intestinal FXR-FGF19-CYP7A1/CYP8B1 Pathway.
Song J, Lu X, Liu D, Zhang Y, Zhai X, Zhou L, Gao J
Journal of agricultural and food chemistry 2023 Sep 27;71(38):14027-14037
Journal of agricultural and food chemistry 2023 Sep 27;71(38):14027-14037
Intercellular adhesion molecule 2 as a novel prospective tumor suppressor induced by ERG promotes ubiquitination-mediated radixin degradation to inhibit gastric cancer tumorigenicity and metastasis.
Tang X, Huang J, Jiang Y, Qiu J, Li T, Li W, Chen Z, Huang Z, Yu X, Yang T, Ji X, Tan R, Lv L, Yang Z, Chen H
Journal of translational medicine 2023 Sep 27;21(1):670
Journal of translational medicine 2023 Sep 27;21(1):670
Red Rice Seed Coat Targeting SPHK2 Ameliorated Alcoholic Liver Disease via Restored Intestinal Barrier and Improved Gut Microbiota in Mice.
Chen Y, Zhao Z, Guo S, Li Y, Yin H, Tian L, Cheng G, Li Y
Nutrients 2023 Sep 27;15(19)
Nutrients 2023 Sep 27;15(19)
DKK1 Promotes Epithelial-Mesenchymal Transition and Cisplatin Resistance in Gastric Cancer via Activation of the PI3K/AKT Pathway.
Li J, Zhang Y, Ye F, Qian P, Qin Z, Li D, Ye L, Feng L
Cancers 2023 Sep 27;15(19)
Cancers 2023 Sep 27;15(19)
Discovery of Salidroside as a Novel Non-Coding RNA Modulator to Delay Cellular Senescence and Promote BK-Dependent Apoptosis in Cerebrovascular Smooth Muscle Cells of Simulated Microgravity Rats.
Ge Y, Zhang B, Song J, Cao Q, Bu Y, Li P, Bai Y, Yang C, Xie M
International journal of molecular sciences 2023 Sep 26;24(19)
International journal of molecular sciences 2023 Sep 26;24(19)
Long intergenic non-coding RNA DIO3OS promotes osteosarcoma metastasis via activation of the TGF-β signaling pathway: a potential diagnostic and immunotherapeutic target for osteosarcoma.
Yuan J, Jia J, Wu T, Du Z, Chen Q, Zhang J, Wu Z, Yuan Z, Zhao X, Liu J, Guo J, Cheng X
Cancer cell international 2023 Sep 26;23(1):215
Cancer cell international 2023 Sep 26;23(1):215
Ar-turmerone inhibits the proliferation and mobility of glioma by downregulating cathepsin B.
Cao W, Chen X, Xiao C, Lin D, Li Y, Luo S, Zeng Z, Sun B, Lei S
Aging 2023 Sep 26;15(18):9377-9390
Aging 2023 Sep 26;15(18):9377-9390
PARP14 inhibition restores PD-1 immune checkpoint inhibitor response following IFNγ-driven acquired resistance in preclinical cancer models.
Wong CW, Evangelou C, Sefton KN, Leshem R, Zhang W, Gopalan V, Chattrakarn S, Fernandez Carro ML, Uzuner E, Mole H, Wilcock DJ, Smith MP, Sergiou K, Telfer BA, Isaac DT, Liu C, Perl NR, Marie K, Lorigan P, Williams KJ, Rao PE, Nagaraju RT, Niepel M, Hurlstone AFL
Nature communications 2023 Sep 26;14(1):5983
Nature communications 2023 Sep 26;14(1):5983
Causal ALS genes impact the MHC class II antigen presentation pathway.
Chi B, Öztürk MM, Paraggio CL, Leonard CE, Sanita ME, Dastpak M, O'Connell JD, Coady JA, Zhang J, Gygi SP, Lopez-Gonzalez R, Yin S, Reed R
Proceedings of the National Academy of Sciences of the United States of America 2023 Sep 26;120(39):e2305756120
Proceedings of the National Academy of Sciences of the United States of America 2023 Sep 26;120(39):e2305756120
Metabolic characteristics of voriconazole - Induced liver injury in rats.
Du Q, Teng M, Yang L, Meng C, Qiu Y, Wang C, Chen J, Wang T, Chen S, Luo Y, Sun J, Dong Y
Chemico-biological interactions 2023 Sep 25;383:110693
Chemico-biological interactions 2023 Sep 25;383:110693
Oryza sativa L. Indica Seed Coat Ameliorated Concanavalin A-Induced Acute Hepatitis in Mice via MDM2/p53 and PKCα/MAPK1 Signaling Pathways.
Zhao Z, Li Y, Guo S, Chen Y, Yin H, Li Y, Cheng G, Tian L
International journal of molecular sciences 2023 Sep 25;24(19)
International journal of molecular sciences 2023 Sep 25;24(19)
Genome-wide enhancer-gene regulatory maps link causal variants to target genes underlying human cancer risk.
Ying P, Chen C, Lu Z, Chen S, Zhang M, Cai Y, Zhang F, Huang J, Fan L, Ning C, Li Y, Wang W, Geng H, Liu Y, Tian W, Yang Z, Liu J, Huang C, Yang X, Xu B, Li H, Zhu X, Li N, Li B, Wei Y, Zhu Y, Tian J, Miao X
Nature communications 2023 Sep 25;14(1):5958
Nature communications 2023 Sep 25;14(1):5958
Repurposing of Ibrutinib and Quizartinib as potent inhibitors of necroptosis.
Huang F, Liang J, Lin Y, Chen Y, Hu F, Feng J, Zeng Q, Han Z, Lin Q, Li Y, Li J, Wu L, Li L
Communications biology 2023 Sep 23;6(1):972
Communications biology 2023 Sep 23;6(1):972
LncRNA CCAT1 facilitates the progression of gastric cancer via PTBP1-mediated glycolysis enhancement.
Zhang C, Wang H, Liu Q, Dai S, Tian G, Wei X, Li X, Zhao L, Shan B
Journal of experimental & clinical cancer research : CR 2023 Sep 23;42(1):246
Journal of experimental & clinical cancer research : CR 2023 Sep 23;42(1):246
RAD51D Secondary Mutation-Mediated Resistance to PARP-Inhibitor-Based Therapy in HGSOC.
Xu J, Dai Y, Gao Y, Chai R, Lu C, Yu B, Kang Y, Xu C
International journal of molecular sciences 2023 Sep 23;24(19)
International journal of molecular sciences 2023 Sep 23;24(19)
Comprehensive Analysis of the Transcriptome-Wide m(6)A Methylome in Shaziling Pig Testicular Development.
Chen C, Tang X, Yan S, Yang A, Xiang J, Deng Y, Yin Y, Chen B, Gu J
International journal of molecular sciences 2023 Sep 23;24(19)
International journal of molecular sciences 2023 Sep 23;24(19)
Tauopathy promotes spinal cord-dependent production of toxic amyloid-beta in transgenic monkeys.
Tu Z, Yan S, Han B, Li C, Liang W, Lin Y, Ding Y, Wei H, Wang L, Xu H, Ye J, Li B, Li S, Li XJ
Signal transduction and targeted therapy 2023 Sep 22;8(1):358
Signal transduction and targeted therapy 2023 Sep 22;8(1):358
Activation of CTNNB1 by deubiquitinase UCHL3-mediated stabilization facilitates bladder cancer progression.
Liu T, Fan MQ, Xie XX, Shu QP, Du XH, Qi LZ, Zhang XD, Zhang MH, Shan G, Du RL, Li SZ
Journal of translational medicine 2023 Sep 22;21(1):656
Journal of translational medicine 2023 Sep 22;21(1):656
FTO-targeted siRNA delivery by MSC-derived exosomes synergistically alleviates dopaminergic neuronal death in Parkinson's disease via m6A-dependent regulation of ATM mRNA.
Geng Y, Long X, Zhang Y, Wang Y, You G, Guo W, Zhuang G, Zhang Y, Cheng X, Yuan Z, Zan J
Journal of translational medicine 2023 Sep 22;21(1):652
Journal of translational medicine 2023 Sep 22;21(1):652
Depletion of G9A attenuates imiquimod-induced psoriatic dermatitis via targeting EDAR-NF-κB signaling in keratinocyte.
Fang Z, Wang Y, Huang B, Chen X, Jiang R, Yin M
Cell death & disease 2023 Sep 22;14(9):627
Cell death & disease 2023 Sep 22;14(9):627
CREB1-driven CXCR4(hi) neutrophils promote skin inflammation in mouse models and human patients.
Chen J, Bai Y, Xue K, Li Z, Zhu Z, Li Q, Yu C, Li B, Shen S, Qiao P, Li C, Luo Y, Qiao H, Dang E, Yin W, Gudjonsson JE, Wang G, Shao S
Nature communications 2023 Sep 22;14(1):5894
Nature communications 2023 Sep 22;14(1):5894
Mometasone Furoate Inhibits the Progression of Head and Neck Squamous Cell Carcinoma via Regulating Protein Tyrosine Phosphatase Non-Receptor Type 11.
Qiu L, Gao Q, Tao A, Jiang J, Li C
Biomedicines 2023 Sep 22;11(10)
Biomedicines 2023 Sep 22;11(10)
Chronic cough relief by allosteric modulation of P2X3 without taste disturbance.
Guo CR, Zhang ZZ, Zhou X, Sun MY, Li TT, Lei YT, Gao YH, Li QQ, Yue CX, Gao Y, Lin YY, Hao CY, Li CZ, Cao P, Zhu MX, Rong MQ, Wang WH, Yu Y
Nature communications 2023 Sep 20;14(1):5844
Nature communications 2023 Sep 20;14(1):5844
The Crosstalk between the EGFR and IFN-γ Pathways and Synergistic Roles in Survival Prediction and Immune Escape in Gliomas.
Zhou X, Liang T, Ge Y, Wang Y, Ma W
Brain sciences 2023 Sep 20;13(9)
Brain sciences 2023 Sep 20;13(9)
SIRT2 inhibition protects against cardiac hypertrophy and ischemic injury.
Yang X, Chang HC, Tatekoshi Y, Mahmoodzadeh A, Balibegloo M, Najafi Z, Wu R, Chen C, Sato T, Shapiro J, Ardehali H
eLife 2023 Sep 20;12
eLife 2023 Sep 20;12
Hepatic soluble epoxide hydrolase activity regulates cerebral Aβ metabolism and the pathogenesis of Alzheimer's disease in mice.
Wu Y, Dong JH, Dai YF, Zhu MZ, Wang MY, Zhang Y, Pan YD, Yuan XR, Guo ZX, Wang CX, Li YQ, Zhu XH
Neuron 2023 Sep 20;111(18):2847-2862.e10
Neuron 2023 Sep 20;111(18):2847-2862.e10
Integration of AIEgens into covalent organic frameworks for pyroptosis and ferroptosis primed cancer immunotherapy.
Zhang L, Song A, Yang QC, Li SJ, Wang S, Wan SC, Sun J, Kwok RTK, Lam JWY, Deng H, Tang BZ, Sun ZJ
Nature communications 2023 Sep 2;14(1):5355
Nature communications 2023 Sep 2;14(1):5355
ALDOC promotes non-small cell lung cancer through affecting MYC-mediated UBE2N transcription and regulating Wnt/β-catenin pathway.
Shang B, Lu F, Jiang S, Xing M, Mao X, Yang G, Zhang H
Aging 2023 Sep 18;15(18):9614-9632
Aging 2023 Sep 18;15(18):9614-9632
Dual single guide RNAs-mediating deletion of mature myostatin peptide results in concomitant muscle fibre hyperplasia and adipocyte hypotrophy in pigs.
Hua Z, Xu K, Xiao W, Shu C, Li N, Li K, Gu H, Zhu Z, Zhang L, Ren H, Zeng Q, Yin Y, Bi Y
Biochemical and biophysical research communications 2023 Sep 17;673:145-152
Biochemical and biophysical research communications 2023 Sep 17;673:145-152
LAD1 promotes malignant progression by diminishing ubiquitin-dependent degradation of vimentin in gastric cancer.
Jiang Y, Feng Y, Huang J, Huang Z, Tan R, Li T, Chen Z, Tang X, Qiu J, Li C, Chen H, Yang Z
Journal of translational medicine 2023 Sep 17;21(1):632
Journal of translational medicine 2023 Sep 17;21(1):632
Multi-omic analysis of mandibuloacral dysplasia type A patient iPSC-derived MSC senescence reveals miR-311 as a novel biomarker for MSC senescence.
He L, Liao J, Liu Z, Wang T, Zhou Y, Wang T, Lei B, Zhou G
Human molecular genetics 2023 Sep 16;32(19):2872-2886
Human molecular genetics 2023 Sep 16;32(19):2872-2886
Phenylalanine-tRNA aminoacylation is compromised by ALS/FTD-associated C9orf72 C4G2 repeat RNA.
Malnar Črnigoj M, Čerček U, Yin X, Ho MT, Repic Lampret B, Neumann M, Hermann A, Rouleau G, Suter B, Mayr M, Rogelj B
Nature communications 2023 Sep 16;14(1):5764
Nature communications 2023 Sep 16;14(1):5764
Sodium hydrosulfide moderately alleviates the hallmark symptoms of Duchenne muscular dystrophy in mdx mice.
Myszka M, Mucha O, Podkalicka P, Waśniowska U, Dulak J, Łoboda A
European journal of pharmacology 2023 Sep 15;955:175928
European journal of pharmacology 2023 Sep 15;955:175928
Denervation aggravates renal ischemia reperfusion injury via BMAL1-mediated Nrf2/ARE pathway.
Dong C, Li J, Tang Q, Wang Y, Zeng C, Du L, Sun Q
Archives of biochemistry and biophysics 2023 Sep 15;746:109736
Archives of biochemistry and biophysics 2023 Sep 15;746:109736
Genetic deletion or pharmacological inhibition of soluble epoxide hydrolase attenuated particulate matter 2.5 exposure mediated lung injury.
Zhang J, Zhang WH, Morisseau C, Zhang M, Dong HJ, Zhu QM, Huo XK, Sun CP, Hammock BD, Ma XC
Journal of hazardous materials 2023 Sep 15;458:131890
Journal of hazardous materials 2023 Sep 15;458:131890
Piperlonguminine attenuates renal fibrosis by inhibiting TRPC6.
Zhou L, Wu K, Gao Y, Qiao R, Tang N, Dong D, Li XQ, Nong Q, Luo DQ, Xiao Q, Fan X, Duan Q, Cao W
Journal of ethnopharmacology 2023 Sep 15;313:116561
Journal of ethnopharmacology 2023 Sep 15;313:116561
The alcohol extracts of Sceptridium ternatum (Thunb.) Lyon exert anti-pulmonary fibrosis effect through targeting SETDB1/STAT3/p-STAT3 signaling.
Zou X, Huang Z, Zhan Z, Yuan M, Zhang Y, Liu T, Hu X, Fan W, Chen P, Qin H, Zhang S, Xia Y, Zheng S, Pan Z, Huang P
Journal of ethnopharmacology 2023 Sep 15;313:116520
Journal of ethnopharmacology 2023 Sep 15;313:116520
Lorazepam Stimulates IL6 Production and Is Associated with Poor Survival Outcomes in Pancreatic Cancer.
Cornwell AC, Tisdale AA, Venkat S, Maraszek KE, Alahmari AA, George A, Attwood K, George M, Rempinski D, Franco-Barraza J, Seshadri M, Parker MD, Cortes Gomez E, Fountzilas C, Cukierman E, Steele NG, Feigin ME
Clinical cancer research : an official journal of the American Association for Cancer Research 2023 Sep 15;29(18):3793-3812
Clinical cancer research : an official journal of the American Association for Cancer Research 2023 Sep 15;29(18):3793-3812
Zbtb14 Promotes Non-Alcoholic Fatty Liver Disease-Associated Fibrosis in Gerbils via the β-Catenin Pathway.
Chen G, Wang X, Zhu Y, Hu H, Chu X
Frontiers in bioscience (Landmark edition) 2023 Sep 15;28(9):205
Frontiers in bioscience (Landmark edition) 2023 Sep 15;28(9):205
Paternal cadmium exposure affects estradiol synthesis by impairing intracellular cholesterol homeostasis and mitochondrial function in offspring female mice.
Zhang Y, Zhou J, Zeng L, Xiong Y, Wang X, Xiang W, Su P
Ecotoxicology and environmental safety 2023 Sep 15;263:115280
Ecotoxicology and environmental safety 2023 Sep 15;263:115280
Seizure enhances SUMOylation and zinc-finger transcriptional repression in neuronal nuclei.
Soon HR, Gaunt JR, Bansal VA, Lenherr C, Sze SK, Ch'ng TH
iScience 2023 Sep 15;26(9):107707
iScience 2023 Sep 15;26(9):107707
Mitoquinone alleviates osteoarthritis progress by activating the NRF2-Parkin axis.
Hou L, Wang G, Zhang X, Lu F, Xu J, Guo Z, Lin J, Zheng Z, Liu H, Hou Y, Sun K, Guo F
iScience 2023 Sep 15;26(9):107647
iScience 2023 Sep 15;26(9):107647
Biglycan regulated colorectal cancer progress by modulating enteric neuron-derived IL-10 and abundance of Bacteroides thetaiotaomicron.
Xu Y, Wang F, Mi K, Wang X, Wang D, Zhao Q, Wang J, Liu Z, Zhang Q, Liu Y, Zhang X, Liu X
iScience 2023 Sep 15;26(9):107515
iScience 2023 Sep 15;26(9):107515
The RNA-Splicing Ligase RTCB Promotes Influenza A Virus Replication by Suppressing Innate Immunity via Interaction with RNA Helicase DDX1.
Cao L, Hui X, Xu T, Mao H, Lin X, Huang K, Zhao L, Jin M
Journal of immunology (Baltimore, Md. : 1950) 2023 Sep 15;211(6):1020-1031
Journal of immunology (Baltimore, Md. : 1950) 2023 Sep 15;211(6):1020-1031
Liver X Receptor LXRα Promotes Grass Carp Reovirus Infection by Attenuating IRF3-CBP Interaction and Inhibiting RLR Antiviral Signaling.
Song YJ, Zhang J, Xu Z, Nie P, Chang MX
Journal of immunology (Baltimore, Md. : 1950) 2023 Sep 15;211(6):1006-1019
Journal of immunology (Baltimore, Md. : 1950) 2023 Sep 15;211(6):1006-1019
Arginine methylation of HSPA8 by PRMT9 inhibits ferroptosis to accelerate hepatitis B virus-associated hepatocellular carcinoma progression.
Deng W, Ai J, Zhang W, Zhou Z, Li M, Yan L, Zhang L, Huang Z, Wu Z, Ai J, Jiang H
Journal of translational medicine 2023 Sep 15;21(1):625
Journal of translational medicine 2023 Sep 15;21(1):625
Systemic gene therapy using an AAV44.9 vector rescues a neonatal lethal mouse model of propionic acidemia.
Chandler RJ, Di Pasquale G, Choi EY, Chang D, Smith SN, Sloan JL, Hoffmann V, Li L, Chiorini JA, Venditti CP
Molecular therapy. Methods & clinical development 2023 Sep 14;30:181-190
Molecular therapy. Methods & clinical development 2023 Sep 14;30:181-190
Catalysis-Mediated Male Contraception through Black Phosphorus Nanosheets.
Yi L, Zhu S, Wu P, Zhang Y, Wang M, Xu P, Zeng J, Wang G, Luo L, Li W
ACS applied materials & interfaces 2023 Sep 13;15(36):42284-42292
ACS applied materials & interfaces 2023 Sep 13;15(36):42284-42292
mTORC1 Regulates the Metabolic Switch of Postnatal Cardiomyocytes During Regeneration.
Paltzer WG, Aballo TJ, Bae J, Hubert KA, Nuttall DJ, Perry C, Wanless KN, Nahlawi R, Ge Y, Mahmoud AI
bioRxiv : the preprint server for biology 2023 Sep 13;
bioRxiv : the preprint server for biology 2023 Sep 13;
YBX1 as an oncogenic factor in T-cell acute lymphoblastic leukemia.
Li H, Zhang D, Fu Q, Wang S, Wang Z, Zhang X, Chen X, Zhu X, An N, Chen Y, Zhou L, Lu D, Zhao N
Blood advances 2023 Sep 12;7(17):4874-4885
Blood advances 2023 Sep 12;7(17):4874-4885
Therapeutic inhibition of miR-155 attenuates liver fibrosis via STAT3 signaling.
Bala S, Zhuang Y, Nagesh PT, Catalano D, Zivny A, Wang Y, Xie J, Gao G, Szabo G
Molecular therapy. Nucleic acids 2023 Sep 12;33:413-427
Molecular therapy. Nucleic acids 2023 Sep 12;33:413-427
A Nucleus-Targeting WT1 Antagonistic Peptide Encapsulated in Polymeric Nanomicelles Combats Refractory Chronic Myeloid Leukemia.
Chen M, Fang X, Du R, Meng J, Liu J, Liu M, Yang Y, Wang C
Pharmaceutics 2023 Sep 12;15(9)
Pharmaceutics 2023 Sep 12;15(9)
A novel recombinant ORF7-siRNA delivered by flexible nano-liposomes inhibits varicella zoster virus infection.
Pei J, Tian Y, Ye W, Han J, Dang Y, Cheng T, Wang W, Zhao Y, Ye W, Huangfu S, Li Y, Zhang F, Lei Y, Qian A
Cell & bioscience 2023 Sep 12;13(1):167
Cell & bioscience 2023 Sep 12;13(1):167
Length limitation of astral microtubules orients cell divisions in murine intestinal crypts.
Saleh J, Fardin MA, Barai A, Soleilhac M, Frenoy O, Gaston C, Cui H, Dang T, Gaudin N, Vincent A, Minc N, Delacour D
Developmental cell 2023 Sep 11;58(17):1519-1533.e6
Developmental cell 2023 Sep 11;58(17):1519-1533.e6
H3K18 lactylation of senescent microglia potentiates brain aging and Alzheimer's disease through the NFκB signaling pathway.
Wei L, Yang X, Wang J, Wang Z, Wang Q, Ding Y, Yu A
Journal of neuroinflammation 2023 Sep 11;20(1):208
Journal of neuroinflammation 2023 Sep 11;20(1):208
The lysosome-mitochondrion crosstalk engaged in silver nanoparticles-disturbed mitochondrial homeostasis.
Liu J, Huang Z, Yin S, Zhou X, Jiang Y, Shao L
The Science of the total environment 2023 Sep 1;889:164078
The Science of the total environment 2023 Sep 1;889:164078
The Exosome-Transmitted lncRNA LOC100132249 Induces Endothelial Dysfunction in Diabetic Retinopathy.
Hu Z, Wang J, Pan T, Li X, Tao C, Wu Y, Wang X, Zhang Z, Liu Y, Zhang W, Xu C, Wu X, Gu Q, Fan Y, Qian H, Mugisha A, Yuan S, Liu Q, Xie P
Diabetes 2023 Sep 1;72(9):1307-1319
Diabetes 2023 Sep 1;72(9):1307-1319
Depleted uranium induces thyroid damage through activation of ER stress via the thrombospondin 1-PERK pathway.
Shu C, Li J, Liu S, Li Y, Ran Y, Zhao Y, Li J, Hao Y
Chemico-biological interactions 2023 Sep 1;382:110592
Chemico-biological interactions 2023 Sep 1;382:110592
Glibenclamide promotes FGF21 secretion in interscapular BAT and attenuates depression-like behaviors in male mice with HFD-induced obesity.
Kuo YY, Tsai HY, Kuo YM, Tzeng SF, Chen PS, Hsu PH, Lin YT, Chen PC
Life sciences 2023 Sep 1;328:121900
Life sciences 2023 Sep 1;328:121900
Gap26 inhibited angiogenesis through the β-catenin-VE-cadherin-VEGFR2-Erk signaling pathway.
Xu C, Zhong W, Zhang H, Jiang J, Zhou H
Life sciences 2023 Sep 1;328:121836
Life sciences 2023 Sep 1;328:121836
Effect of Tamoxifen on Proteome Expression during In Vitro Myogenesis in Murine Skeletal Muscle C(2)C(12) Cells.
Morris EA, Abreu A, Scordilis SP
Journal of proteome research 2023 Sep 1;22(9):3040-3053
Journal of proteome research 2023 Sep 1;22(9):3040-3053
Epithelial TIPE1 Protein Guards against Colitis by Inhibiting TNF-α-Mediated Inflammation.
Lou Y, Jiang S, Song M, Wang H, Han M, Tian X, Zhao Y, Gao J, Song Y, Ma S, Zhao P, Zheng Q, Niu Z, Zhang W, Chang T, Chen YH, Wang H
Journal of immunology (Baltimore, Md. : 1950) 2023 Sep 1;211(5):874-884
Journal of immunology (Baltimore, Md. : 1950) 2023 Sep 1;211(5):874-884
Protein arginine methyltransferase 5 mediates arginine symmetric dimethylation of influenza A virus PB2 and supports viral replication.
Sun H, Tu S, Luo D, Dai C, Jin M, Chen H, Zou J, Zhou H
Journal of medical virology 2023 Oct;95(10):e29171
Journal of medical virology 2023 Oct;95(10):e29171
Paraquat-induced ferroptosis suppression via NRF2 expression regulation.
Cai Q, Shen Q, Zhu W, Zhang S, Ke J, Lu Z
Toxicology in vitro : an international journal published in association with BIBRA 2023 Oct;92:105655
Toxicology in vitro : an international journal published in association with BIBRA 2023 Oct;92:105655
Graphene oxide had adverse effects on sperm motility and morphology through oxidative stress.
Chen Q, Li L, Zhao J, Zhang Y, Xue X
Toxicology in vitro : an international journal published in association with BIBRA 2023 Oct;92:105653
Toxicology in vitro : an international journal published in association with BIBRA 2023 Oct;92:105653
Knockdown of LINC00702 inhibits the growth and induces apoptosis of breast cancer through the Wnt/β-catenin pathway.
Chai D, Yang C, Liu Y, Li H, Lian B, Bai Z, Li J
Heliyon 2023 Oct;9(10):e20651
Heliyon 2023 Oct;9(10):e20651
Resveratrol inhibits ferroptosis via activating NRF2/GPX4 pathway in mice with spinal cord injury.
Ni C, Ye Q, Mi X, Jiao D, Zhang S, Cheng R, Fang Z, Fang M, Ye X
Microscopy research and technique 2023 Oct;86(10):1378-1390
Microscopy research and technique 2023 Oct;86(10):1378-1390
ANKRD22 knockdown suppresses papillary thyroid cell carcinoma growth and migration and modulates the Wnt/β-catenin signaling pathway.
Wu Y, Chen W, Zhang B, Liu H
Tissue & cell 2023 Oct;84:102193
Tissue & cell 2023 Oct;84:102193
Oxidative stress mediates the inhibitory effects of Manzamine A on uterine leiomyoma cell proliferation and extracellular matrix deposition via SOAT inhibition.
Lin LC, Chang HY, Kuo TT, Chen HY, Liu WS, Lo YJ, Hsia SM, Huang TC
Redox biology 2023 Oct;66:102861
Redox biology 2023 Oct;66:102861
Characterization of SHARPIN knockout Syrian hamsters developed using CRISPR/Cas9 system.
Miao J, Lan T, Guo H, Wang J, Zhang G, Wang Z, Yang P, Li H, Zhang C, Wang Y, Li XM, Miao M
Animal models and experimental medicine 2023 Oct;6(5):489-498
Animal models and experimental medicine 2023 Oct;6(5):489-498
Rutaecarpine ameliorates osteoarthritis by inhibiting PI3K/AKT/NF‑κB and MAPK signalling transduction through integrin αVβ3.
Wan J, Li M, Yuan X, Yu X, Chen A, Shao M, Kang H, Cheng P
International journal of molecular medicine 2023 Oct;52(4)
International journal of molecular medicine 2023 Oct;52(4)
MBNL1‑AS1 attenuates tumor cell proliferation by regulating the miR‑29c‑3p/BVES signal in colorectal cancer.
Chen WS, Zhang X, Zhao ZF, Che XM
Oncology reports 2023 Oct;50(4)
Oncology reports 2023 Oct;50(4)
Interleukin-22 Inhibits Apoptosis of Gingival Epithelial Cells Through TGF-β Signaling Pathway During Periodontitis.
Huang Y, Zhang L, Tan L, Zhang C, Li X, Wang P, Gao L, Zhao C
Inflammation 2023 Oct;46(5):1871-1886
Inflammation 2023 Oct;46(5):1871-1886
Dysregulation of iron homeostasis by TfR-1 renders EZH2 wild type diffuse large B-cell lymphoma resistance to EZH2 inhibition.
Yu L, Wang YF, Xiao J, Shen QQ, Chi SS, Gao YL, Lin DZ, Ding J, Fang YF, Chen Y
Acta pharmacologica Sinica 2023 Oct;44(10):2113-2124
Acta pharmacologica Sinica 2023 Oct;44(10):2113-2124
Chronic β-adrenergic stress contributes to cardiomyopathy in rodents with collagen-induced arthritis.
Zhu ZD, Zhang M, Wang Z, Jiang CR, Huang CJ, Cheng HJ, Guan QY, Su TT, Wang MM, Gao Y, Wu HF, Wei W, Han YS, Wang QT
Acta pharmacologica Sinica 2023 Oct;44(10):1989-2003
Acta pharmacologica Sinica 2023 Oct;44(10):1989-2003
A novel small-molecular CCR5 antagonist promotes neural repair after stroke.
Wu QL, Cui LY, Ma WY, Wang SS, Zhang Z, Feng ZP, Sun HS, Chu SF, He WB, Chen NH
Acta pharmacologica Sinica 2023 Oct;44(10):1935-1947
Acta pharmacologica Sinica 2023 Oct;44(10):1935-1947
Pingxiao capsule inhibits lung metastasis of triple-negative breast cancer and sensitizes breast cancer to radiotherapy.
Wenjuan T, Yu HU, Man Z, Mingzhi D, Tieming L, Ammar S, Yingzhuan Z, Yanmin Z
Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan 2023 Oct;43(5):897-905
Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan 2023 Oct;43(5):897-905
Circular RNA EIF3I promotes papillary thyroid cancer progression by interacting with AUF1 to increase Cyclin D1 production.
Yao X, Liu H, Wang Z, Lu F, Chen W, Feng Q, Miao Y, Zhang J, Wang Y, Chen Y, Xue L, Liu Y, Chen L, Zhang Q
Oncogene 2023 Oct;42(43):3206-3218
Oncogene 2023 Oct;42(43):3206-3218
Oncogenic BRAF noncanonically promotes tumor metastasis by mediating VASP phosphorylation and filopodia formation.
Pan W, Tian Y, Zheng Q, Yang Z, Qiang Y, Zhang Z, Zhang N, Xiong J, Zhu X, Wei L, Li F
Oncogene 2023 Oct;42(43):3194-3205
Oncogene 2023 Oct;42(43):3194-3205
Upregulation by duloxetine of the transforming growth factor-α-induced migration of hepatocellular carcinoma cells via enhancement of the c-Jun N-terminal kinase activity.
Matsushima-Nishiwaki R, Kamoi S, Kozawa O
Cell biochemistry and function 2023 Oct;41(7):814-822
Cell biochemistry and function 2023 Oct;41(7):814-822
Differential traits between microvesicles and exosomes in enterovirus infection.
Fu Y, Xiong S
MedComm 2023 Oct;4(5):e384
MedComm 2023 Oct;4(5):e384
SEMA3B-AS1 suppresses colorectal carcinoma progression by inhibiting Semaphorin 3B-dependent VEGF signaling pathway activation.
Wang YQ, Chen H, Xu S, Liao CR, Xu A, Han Y, Yang MH, Zhao L, Hu SS, Wang L, Li QY, Zhan LY, Ding YQ, Wang S
MedComm 2023 Oct;4(5):e365
MedComm 2023 Oct;4(5):e365
Kif15 deficiency contributes to depression-like behavior in mice.
Wang J, Tu Q, Zhang S, He X, Ma C, Qian X, Wu R, Shi X, Yang Z, Liu Y, Dong Z, Liu M
Metabolic brain disease 2023 Oct;38(7):2369-2381
Metabolic brain disease 2023 Oct;38(7):2369-2381
Autophagy induced by human adenovirus B7 structural protein VI inhibits viral replication.
Zhang L, Duan Y, Wang W, Li Q, Tian J, Zhu Y, Wang R, Xie Z
Virologica Sinica 2023 Oct;38(5):709-722
Virologica Sinica 2023 Oct;38(5):709-722
HBV precore G1896A mutation promotes growth of hepatocellular carcinoma cells by activating ERK/MAPK pathway.
Zhao B, Qiao H, Zhao Y, Gao Z, Wang W, Cui Y, Li J, Guo Z, Chuai X, Chiu S
Virologica Sinica 2023 Oct;38(5):680-689
Virologica Sinica 2023 Oct;38(5):680-689
METTL3-mediated m6A modification of pri-miR-148a-3p affects prostate cancer progression by regulating TXNIP.
Li G, Liu J, Wang Y, Liu H, Fu J, Zhao Y, Huang Y
Environmental toxicology 2023 Oct;38(10):2377-2390
Environmental toxicology 2023 Oct;38(10):2377-2390
Lens epithelial cell-derived exosome inhibits angiogenesis in ocular pathological neovascularization through its delivery of miR-146a-5p.
Pan T, Wu Y, Zhang X, Wang J, Wang X, Gu Q, Xu C, Fan Y, Li X, Xie P, Liu Q, Hu Z
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Oct;37(10):e23192
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Oct;37(10):e23192
Hypomethylation of CD3D promoter induces immune cell infiltration and supports malignant phenotypes in uveal melanoma.
Zhang C, Wu S
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Oct;37(10):e23128
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Oct;37(10):e23128
NPLC0393 from Gynostemma pentaphyllum ameliorates Alzheimer's disease-like pathology in mice by targeting protein phosphatase magnesium-dependent 1A phosphatase.
Lv J, Shen X, Shen X, Zhao S, Xu R, Yan Q, Lu J, Zhu D, Zhao Y, Dong J, Wang J, Shen X
Phytotherapy research : PTR 2023 Oct;37(10):4771-4790
Phytotherapy research : PTR 2023 Oct;37(10):4771-4790
Cryptotanshinone alleviates radiation-induced lung fibrosis via modulation of gut microbiota and bile acid metabolism.
Li Z, Shen Y, Xin J, Xu X, Ding Q, Chen W, Wang J, Lv Y, Wei X, Wei Y, Zhang W, Zu X, Wang S
Phytotherapy research : PTR 2023 Oct;37(10):4557-4571
Phytotherapy research : PTR 2023 Oct;37(10):4557-4571
Paternal cadmium exposure induces glucolipid metabolic reprogramming in offspring mice via PPAR signaling pathway.
Zeng L, Zhou J, Zhang Y, Wang X, Li Y, Song J, Shao J, Su P
Chemosphere 2023 Oct;339:139592
Chemosphere 2023 Oct;339:139592
BCKDHA contributes to melanoma progression by promoting the expressions of lipogenic enzymes FASN and ACLY.
Tian Y, Ma J, Wang M, Yi X, Guo S, Wang H, Zhang H, Wang H, Yang Y, Zhang B, Du J, Shi Q, Gao T, Li C, Guo W
Experimental dermatology 2023 Oct;32(10):1633-1643
Experimental dermatology 2023 Oct;32(10):1633-1643
Long-term and liver-selected ginsenoside C-K nanoparticles retard NAFLD progression by restoring lipid homeostasis.
Yue C, Li D, Fan S, Tao F, Yu Y, Lu W, Chen Q, Yuan A, Wu J, Zhao G, Dong H, Hu Y
Biomaterials 2023 Oct;301:122291
Biomaterials 2023 Oct;301:122291
TRAP1 inhibits MARCH5-mediated MIC60 degradation to alleviate mitochondrial dysfunction and apoptosis of cardiomyocytes under diabetic conditions.
Zhang L, Luo Y, Lv L, Chen S, Liu G, Zhao T
Cell death and differentiation 2023 Oct;30(10):2336-2350
Cell death and differentiation 2023 Oct;30(10):2336-2350
The E3 ubiquitin ligase TRIM17 promotes gastric cancer survival and progression via controlling BAX stability and antagonizing apoptosis.
Shen J, Yang H, Qiao X, Chen Y, Zheng L, Lin J, Lang J, Yu Q, Wang Z
Cell death and differentiation 2023 Oct;30(10):2322-2335
Cell death and differentiation 2023 Oct;30(10):2322-2335
Multiple sevoflurane exposures during mid-trimester induce neurotoxicity in the developing brain initiated by 15LO2-Mediated ferroptosis.
Jiang Q, Wang C, Gao Q, Wu Z, Zhao P
CNS neuroscience & therapeutics 2023 Oct;29(10):2972-2985
CNS neuroscience & therapeutics 2023 Oct;29(10):2972-2985
Treponema pallidum membrane protein Tp47 induced autophagy and inhibited cell migration in HMC3 cells via the PI3K/AKT/FOXO1 pathway.
Xie L, Li W, Zheng XQ, Liu LL, Lin LR, Niu JJ, Yang TC
Journal of cellular and molecular medicine 2023 Oct;27(20):3065-3074
Journal of cellular and molecular medicine 2023 Oct;27(20):3065-3074
Oxytocin Receptor in Cerebellar Purkinje Cells Does Not Engage in Autism-Related Behaviors.
Shen LP, Li W, Pei LZ, Yin J, Xie ST, Li HZ, Yan C, Wang JJ, Zhang Q, Zhang XY, Zhu JN
Cerebellum (London, England) 2023 Oct;22(5):888-904
Cerebellum (London, England) 2023 Oct;22(5):888-904
Depleting ANTXR1 suppresses glioma growth via deactivating PI3K/AKT pathway.
Zhou C, Liang A, Zhang J, Leng J, Xi B, Zhou B, Yang Y, Zhu R, Zhong L, Jiang X, Wan D
Cell cycle (Georgetown, Tex.) 2023 Oct;22(19):2097-2112
Cell cycle (Georgetown, Tex.) 2023 Oct;22(19):2097-2112
Cooperative effects of SIRT1 and SIRT2 on APP acetylation.
Li N, Bai N, Zhao X, Cheng R, Wu X, Jiang B, Li X, Xue M, Xu H, Guo Q, Guo W, Ma M, Cao S, Feng Y, Song X, Wang Z, Zhang X, Zou Y, Wang D, Liu H, Cao L
Aging cell 2023 Oct;22(10):e13967
Aging cell 2023 Oct;22(10):e13967
Oxidative stress and inflammation are mediated via aryl hydrocarbon receptor signalling in idiopathic membranous nephropathy.
Wang YN, Miao H, Yu XY, Guo Y, Su W, Liu F, Cao G, Zhao YY
Free radical biology & medicine 2023 Oct;207:89-106
Free radical biology & medicine 2023 Oct;207:89-106
Glycogen synthase kinase 3 controls T-cell exhaustion by regulating NFAT activation.
Fu Y, Wang J, Liu C, Liao K, Gao X, Tang R, Fan B, Hong Y, Xiao N, Xiao C, Liu WH
Cellular & molecular immunology 2023 Oct;20(10):1127-1139
Cellular & molecular immunology 2023 Oct;20(10):1127-1139
Aquaporin-7 Facilitates Proliferation and Adipogenic Differentiation of Mouse Bone Marrow Mesenchymal Stem Cells by Regulating Hydrogen Peroxide Transport.
Ma Y, Zhang J, Li Y, Hu H, Ye Q, Yang C, Yang L, Zhang B, Ma T
Stem cell reviews and reports 2023 Oct;19(7):2378-2390
Stem cell reviews and reports 2023 Oct;19(7):2378-2390
NMDA receptor activation induces damage of alveolar type II cells and lung fibrogenesis through ferroptosis.
Cheng HP, Feng DD, Li XH, Gao LH, Qiu YJ, Liang XY, Zhou Y, Huang P, Shao M, Zhang YN, Chang YF, Fu JF, Huang YH, Liu W, Tang SY, Li C, Luo ZQ
Biochimica et biophysica acta. Molecular cell research 2023 Oct;1870(7):119535
Biochimica et biophysica acta. Molecular cell research 2023 Oct;1870(7):119535
N-glycosylation by N-acetylglucosaminyltransferase IVa enhances the interaction of integrin β1 with vimentin and promotes hepatocellular carcinoma cell motility.
Yang D, Han F, Cai J, Sun H, Wang F, Jiang M, Zhang M, Yuan M, Zhou W, Li H, Yang L, Bai Y, Xiao L, Dong H, Cheng Q, Mao H, Zhou L, Wang R, Li Y, Nie H
Biochimica et biophysica acta. Molecular cell research 2023 Oct;1870(7):119513
Biochimica et biophysica acta. Molecular cell research 2023 Oct;1870(7):119513
Streptococcus uberis induced expressions of pro-inflammatory IL-6, TNF-α, and IFN-γ in bovine mammary epithelial cells associated with inhibited autophagy and autophagy flux formation.
Khan S, Yang J, Cobo ER, Wang Y, Xu M, Wang T, Shi Y, Liu G, Han B
Microbial pathogenesis 2023 Oct;183:106270
Microbial pathogenesis 2023 Oct;183:106270
Deoxynivalenol induces endoplasmic reticulum stress-associated apoptosis via the IRE1/JNK/CHOP pathway in porcine alveolar macrophage 3D4/21 cells.
Zhang J, Zhao Q, Xue Z, Zhang S, Ren Z, Chen S, Zhou A, Chen H, Liu Y
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2023 Oct;180:114033
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2023 Oct;180:114033
Eph receptor A4 regulates motor neuron ferroptosis in spinal cord ischemia/reperfusion injury in rats.
Dong Y, Ai C, Chen Y, Zhang Z, Zhang D, Liu S, Tong X, Ma H
Neural regeneration research 2023 Oct;18(10):2219-2228
Neural regeneration research 2023 Oct;18(10):2219-2228
M2 macrophages mediate fibrotic scar formation in the early stages after cerebral ischemia in rats.
Huang JG, Ren JX, Chen Y, Tian MF, Zhou L, Wen J, Song XS, Wu YL, Yang QH, Jiang PR, Wang JN, Yang Q
Neural regeneration research 2023 Oct;18(10):2208-2218
Neural regeneration research 2023 Oct;18(10):2208-2218
Body Weight Support Treadmill Training Combined With Sciatic Nerve Electrical Stimulation Ameliorating Motor Function by Enhancing PI3K/Akt Proteins Expression via BDNF/TrkB Signaling Pathway in Rats with Spinal Cord Injury.
Xu Q, Li Z, Su J, Hu M, Yin Q, Chen S, Song J, Chen H
World neurosurgery 2023 Oct;178:e239-e253
World neurosurgery 2023 Oct;178:e239-e253
Ootheca mantidis mitigates renal fibrosis in mice by the suppression of apoptosis via increasing the gut microbe Akkermansia muciniphila and modulating glutamine metabolism.
Wang J, Guo X, Zou Z, Yu M, Li X, Xu H, Chen Y, Jiao T, Wang K, Ma Y, Jiang J, Liang X, Wang J, Xie C, Zhong Y
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Oct;166:115434
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Oct;166:115434
Atorvastatin rescues vascular endothelial injury in hypertension by WWP2-mediated ubiquitination and degradation of ATP5A.
Yin Z, You S, Zhang S, Zhang L, Wu B, Huang X, Lu S, Cao L, Zhang Y, Li D, Zhang X, Liu J, Sun Y, Zhang N
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Oct;166:115228
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Oct;166:115228
CircABPD1 alleviates oxidative lung injury of bronchopulmonary dysplasia through regulating miR-330-3p/HIF1α axis.
Li H, Ma K, Dou H, Liu L, Qian Y, Li S, Chen J, Han S, Gu X, Yin J
The international journal of biochemistry & cell biology 2023 Oct;163:106464
The international journal of biochemistry & cell biology 2023 Oct;163:106464
Knockdown of Mmu-circ-0001380 Attenuates Myocardial Ischemia/Reperfusion Injury via Modulating miR-106b-5p/Phlpp2 Axis.
Wang L, Wang C, Sun Z, Du A, Shan F, Sun Z
Journal of cardiovascular translational research 2023 Oct;16(5):1064-1077
Journal of cardiovascular translational research 2023 Oct;16(5):1064-1077
Quercetin attenuates avermectin-induced cardiac injury in carp through inflammation, oxidative stress, apoptosis and autophagy.
Xu B, Yin J, Qiang J, Gan J, Xu X, Li X, Hu Z, Dong Z
Fish & shellfish immunology 2023 Oct;141:109054
Fish & shellfish immunology 2023 Oct;141:109054
Design, synthesis and biological evaluation of novel modified dual-target shikonin derivatives for colorectal cancer treatment.
Ma Y, Lai X, Wen Z, Zhou Z, Yang M, Chen Q, Wang X, Mei F, Yang L, Yin T, Sun S, Lu G, Qi J, Lin H, Han H, Yang Y
Bioorganic chemistry 2023 Oct;139:106703
Bioorganic chemistry 2023 Oct;139:106703
Parkin regulates IGF2BP3 through ubiquitination in the tumourigenesis of cervical cancer.
Sun X, Ye G, Li J, Shou H, Bai G, Zhang J
Clinical and translational medicine 2023 Oct;13(10):e1457
Clinical and translational medicine 2023 Oct;13(10):e1457
KCTD4 interacts with CLIC1 to disrupt calcium homeostasis and promote metastasis in esophageal cancer.
Zheng C, Yu X, Xu T, Liu Z, Jiang Z, Xu J, Yang J, Zhang G, He Y, Yang H, Shi X, Li Z, Liu J, Xu WW
Acta pharmaceutica Sinica. B 2023 Oct;13(10):4217-4233
Acta pharmaceutica Sinica. B 2023 Oct;13(10):4217-4233
Monoclonal antibody targeting mu-opioid receptor attenuates morphine tolerance via enhancing morphine-induced receptor endocytosis.
Zhang JJ, Song CG, Wang M, Zhang GQ, Wang B, Chen X, Lin P, Zhu YM, Sun ZC, Wang YZ, Jiang JL, Li L, Yang XM, Chen ZN
Journal of pharmaceutical analysis 2023 Oct;13(10):1135-1152
Journal of pharmaceutical analysis 2023 Oct;13(10):1135-1152
Equine β-defensin 1 regulates cytokine expression and phagocytosis in S. aureus-infected mouse monocyte macrophages via the Paxillin-FAK-PI3K pathway.
Pei L, Hou Y, Feng Y, Li F, Su H, Zhang Y, Song Y, Liu K, Cao G
International immunopharmacology 2023 Oct;123:110793
International immunopharmacology 2023 Oct;123:110793
Autophagy induced by PP121 alleviates MSU crystal-induced acute gouty arthritis via inhibition of the NLRP3 inflammasome.
Yuan W, Liu T, Wang YY, He S, Zhang F, Wang XB, Deng SH, Zhang T, Wu DM, Xu Y
International immunopharmacology 2023 Oct;123:110756
International immunopharmacology 2023 Oct;123:110756
Mitochonic acid 5 rescues cardiomyocytes from doxorubicin-induced toxicity via repressing the TNF-α/NF-κB/NLRP3-mediated pyroptosis.
Zha W, Zhao Q, Xiao Y, Gan Y, Wei J, Yu M, Xu Y, Xu Q, Wu S, Yu W
International immunopharmacology 2023 Oct;123:110736
International immunopharmacology 2023 Oct;123:110736
HMGB1 induces macrophage pyroptosis in chronic endometritis.
Yang G, Zhang Q, Tan J, Xiong Y, Liang Y, Yan J, Gu F, Xu Y
International immunopharmacology 2023 Oct;123:110706
International immunopharmacology 2023 Oct;123:110706
Baicalein enhances immune response in TNBC by inhibiting leptin expression of adipocytes.
Liu M, Li C, Qu J, Sun S, Zhao Z, Wang W, Lv W, Zhang Y, Cai Y, Zhao F, Wu F, Zhang S, Zhao X
Cancer science 2023 Oct;114(10):3834-3847
Cancer science 2023 Oct;114(10):3834-3847
The PRX-1/TLR4 axis promotes hypoxia-induced radiotherapy resistance in non-small cell lung cancer by targeting the NF-κB/p65 pathway.
Hao J, Song Z, Su J, Li L, Zou L, Zou K
Cellular signalling 2023 Oct;110:110806
Cellular signalling 2023 Oct;110:110806
The MAEL expression in mitochondria of human spermatozoa and the association with asthenozoospermia.
Cheng YS, Chen HY, Lin YC, Lin YS, Yeh YC, Yeh YH, Cheng YH, Lin YM, Weng HY, Lin TY, Lin SC
Andrology 2023 Oct;11(7):1286-1294
Andrology 2023 Oct;11(7):1286-1294
Liquiritigenin regulates insulin sensitivity and ameliorates inflammatory responses in the nonalcoholic fatty liver by activation PI3K/AKT pathway.
Bao L, Hao P, Jiang M, Chu W
Chemical biology & drug design 2023 Oct;102(4):793-804
Chemical biology & drug design 2023 Oct;102(4):793-804
Retinal Microenvironment-Protected Rhein-GFFYE Nanofibers Attenuate Retinal Ischemia-Reperfusion Injury via Inhibiting Oxidative Stress and Regulating Microglial/Macrophage M1/M2 Polarization.
Zhang Z, Peng S, Xu T, Liu J, Zhao L, Xu H, Zhang W, Zhu Y, Yang Z
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Oct;10(30):e2302909
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Oct;10(30):e2302909
Chlorogenic Acid Ameliorates Post-Infectious Irritable Bowel Syndrome by Regulating Extracellular Vesicles of Gut Microbes.
Zheng C, Zhong Y, Zhang W, Wang Z, Xiao H, Zhang W, Xie J, Peng X, Luo J, Xu W
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Oct;10(28):e2302798
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Oct;10(28):e2302798
Novel role for epalrestat: protecting against NLRP3 inflammasome-driven NASH by targeting aldose reductase.
Shi W, Xu G, Gao Y, Zhao J, Liu T, Zhao J, Yang H, Wei Z, Li H, Xu AL, Bai Z, Xiao X
Journal of translational medicine 2023 Oct 7;21(1):700
Journal of translational medicine 2023 Oct 7;21(1):700
Chronic stress hinders sensory axon regeneration via impairing mitochondrial cristae and OXPHOS.
Ruan Y, Cheng J, Dai J, Ma Z, Luo S, Yan R, Wang L, Zhou J, Yu B, Tong X, Shen H, Zhou L, Yuan TF, Han Q
Science advances 2023 Oct 6;9(40):eadh0183
Science advances 2023 Oct 6;9(40):eadh0183
PI3K/mTOR inhibitors promote G6PD autophagic degradation and exacerbate oxidative stress damage to radiosensitize small cell lung cancer.
Deng H, Chen Y, Wang L, Zhang Y, Hang Q, Li P, Zhang P, Ji J, Song H, Chen M, Jin Y
Cell death & disease 2023 Oct 6;14(10):652
Cell death & disease 2023 Oct 6;14(10):652
Platycodin D induces apoptotic cell death through PI3K/AKT and MAPK/ERK pathways and synergizes with venetoclax in acute myeloid leukemia.
Jiang X, Lin Y, Zhao M, Li Y, Ye P, Pei R, Lu Y, Jiang L
European journal of pharmacology 2023 Oct 5;956:175957
European journal of pharmacology 2023 Oct 5;956:175957
Silence of linc00023 inhibits pyroptosis and promotes cell proliferation via regulating p53.
Zhu A, Cheng C, Lin S, Hong Z, Shi Z, Deng H, Zhang G
Gene 2023 Oct 5;882:147628
Gene 2023 Oct 5;882:147628
Zigui-Yichong-Fang protects against cyclophosphamide-induced premature ovarian insufficiency via the SIRT1/Foxo3a pathway.
Xiu Z, Tang S, Kong P, Yan M, Tong X, Liu X, Liang X, Li R, Duan Y
Journal of ethnopharmacology 2023 Oct 5;314:116608
Journal of ethnopharmacology 2023 Oct 5;314:116608
ZeXieYin Formula alleviates TMAO-induced cognitive impairment by restoring synaptic plasticity damage.
Liu J, Zhou S, Wang Y, Liu J, Sun S, Sun Y, Xu P, Xu X, Zhu B, Wu H
Journal of ethnopharmacology 2023 Oct 5;314:116604
Journal of ethnopharmacology 2023 Oct 5;314:116604
Design, synthesis, and biological evaluation of a series of new anthraquinone derivatives as anti-ZIKV agents.
Zhu Y, Yu J, Chen T, Liu W, Huang Y, Li J, Zhang B, Zhu G, He Z, Long Y, Yuan J
European journal of medicinal chemistry 2023 Oct 5;258:115620
European journal of medicinal chemistry 2023 Oct 5;258:115620
Long non-coding RNA colon cancer-associated transcript 1-Vimentin axis promoting the migration and invasion of HeLa cells.
Li Z, Yuan J, Da Q, Yan Z, Qu J, Li D, Liu X, Zhan Q, Liu J
Chinese medical journal 2023 Oct 5;136(19):2351-2361
Chinese medical journal 2023 Oct 5;136(19):2351-2361
Hemizygous variants in protein phosphatase 1 regulatory subunit 3F (PPP1R3F) are associated with a neurodevelopmental disorder characterized by developmental delay, intellectual disability and autistic features.
Liu Z, Xin B, Smith IN, Sency V, Szekely J, Alkelai A, Shuldiner A, Efthymiou S, Rajabi F, Coury S, Brownstein CA, Rudnik-Schöneborn S, Bruel AL, Thevenon J, Zeidler S, Jayakar P, Schmidt A, Cremer K, Engels H, Peters SO, Zaki MS, Duan R, Zhu C, Xu Y, Gao C, Sepulveda-Morales T, Maroofian R, Alkhawaja IA, Khawaja M, Alhalasah H, Houlden H, Madden JA, Turchetti V, Marafi D, Agrawal PB, Schatz U, Rotenberg A, Rotenberg J, Mancini GMS, Bakhtiari S, Kruer M, Thiffault I, Hirsch S, Hempel M, Stühn LG, Haack TB, Posey JE, Lupski JR, Lee H, Sarn NB, Eng C, Gonzaga-Jauregui C, Zhang B, Wang H
Human molecular genetics 2023 Oct 4;32(20):2981-2995
Human molecular genetics 2023 Oct 4;32(20):2981-2995
LINC00922 decoys SIRT3 to facilitate the metastasis of colorectal cancer through up-regulation the H3K27 crotonylation of ETS1 promoter.
Liao M, Sun X, Zheng W, Wu M, Wang Y, Yao J, Ma Y, Gao S, Pei D
Molecular cancer 2023 Oct 4;22(1):163
Molecular cancer 2023 Oct 4;22(1):163
PACS-2 deficiency aggravates tubular injury in diabetic kidney disease by inhibiting ER-phagy.
Yang J, Li L, Li C, Chen W, Liu Y, Luo S, Zhao C, Han Y, Yang M, Zhao H, Jiang N, Xi Y, Tang C, Cai J, Xiao L, Liu H, Sun L
Cell death & disease 2023 Oct 4;14(10):649
Cell death & disease 2023 Oct 4;14(10):649
Distinct functions of EHMT1 and EHMT2 in cancer chemotherapy and immunotherapy.
Kang Z, Fu P, Ma H, Li T, Lu K, Liu J, Ginjala V, Romanienko P, Feng Z, Guan M, Ganesan S, Xia B
bioRxiv : the preprint server for biology 2023 Oct 4;
bioRxiv : the preprint server for biology 2023 Oct 4;
EGR1 functions as a new host restriction factor for SARS-CoV-2 to inhibit virus replication through the E3 ubiquitin ligase MARCH8.
Zhao Y, Sui L, Wu P, Li L, Liu L, Ma B, Wang W, Chi H, Wang Z-D, Wei Z, Hou Z, Zhang K, Niu J, Jin N, Li C, Zhao J, Wang G, Liu Q
Journal of virology 2023 Oct 31;97(10):e0102823
Journal of virology 2023 Oct 31;97(10):e0102823
Collagen 1-mediated CXCL1 secretion in tumor cells activates fibroblasts to promote radioresistance of esophageal cancer.
Yang X, Chen X, Zhang S, Fan W, Zhong C, Liu T, Cheng G, Zhu L, Liu Q, Xi Y, Tan W, Lin D, Wu C
Cell reports 2023 Oct 31;42(10):113270
Cell reports 2023 Oct 31;42(10):113270
Aspartyl-tRNA synthetase 2 orchestrates iron-sulfur metabolism in hematopoietic stem cells via fine-tuning alternative RNA splicing.
Gu X, Li K, Zhang M, Chen Y, Zhou J, Yao C, Zang Y, He J, Wan J, Guo B
Cell reports 2023 Oct 31;42(10):113264
Cell reports 2023 Oct 31;42(10):113264
Mechanotransduction in response to ECM stiffening impairs cGAS immune signaling in tumor cells.
Liu Y, Yao X, Zhao Y, Fang D, Shi L, Yang L, Song G, Cai K, Li L, Deng Q, Li M, Luo Z
Cell reports 2023 Oct 31;42(10):113213
Cell reports 2023 Oct 31;42(10):113213
CPSF6 regulates alternative polyadenylation and proliferation of cancer cells through phase separation.
Liu S, Wu R, Chen L, Deng K, Ou X, Lu X, Li M, Liu C, Chen S, Fu Y, Xu A
Cell reports 2023 Oct 31;42(10):113197
Cell reports 2023 Oct 31;42(10):113197
PP2C phosphatases Ptc1 and Ptc2 dephosphorylate PGK1 to regulate autophagy and aflatoxin synthesis in the pathogenic fungus Aspergillus flavus.
Zhu Z, Yang M, Yang G, Zhang B, Cao X, Yuan J, Ge F, Wang S
mBio 2023 Oct 31;14(5):e0097723
mBio 2023 Oct 31;14(5):e0097723
Self-promoted electroactive biomimetic mineralized scaffolds for bacteria-infected bone regeneration.
Li Z, He D, Guo B, Wang Z, Yu H, Wang Y, Jin S, Yu M, Zhu L, Chen L, Ding C, Wu X, Wu T, Gong S, Mao J, Zhou Y, Luo D, Liu Y
Nature communications 2023 Oct 31;14(1):6963
Nature communications 2023 Oct 31;14(1):6963
Cryo-EM structure of human O-GlcNAcylation enzyme pair OGT-OGA complex.
Lu P, Liu Y, He M, Cao T, Yang M, Qi S, Yu H, Gao H
Nature communications 2023 Oct 31;14(1):6952
Nature communications 2023 Oct 31;14(1):6952
RNA 5-Methylcytosine regulators are associated with cell adhesion and predict prognosis of endometrial cancer.
Yang S, Luo Y, Zhou D, Xiang J, Xi X
Translational cancer research 2023 Oct 31;12(10):2556-2571
Translational cancer research 2023 Oct 31;12(10):2556-2571
Moschus ameliorates glutamate-induced cellular damage by regulating autophagy and apoptosis pathway.
Xie D, Song C, Qin T, Zhai Z, Cai J, Dai J, Sun T, Xu Y
Scientific reports 2023 Oct 30;13(1):18586
Scientific reports 2023 Oct 30;13(1):18586
Hepatic conversion of acetyl-CoA to acetate plays crucial roles in energy stress.
Wang J, Wen Y, Zhao W, Zhang Y, Lin F, Ouyang C, Wang H, Yao L, Ma H, Zhuo Y, Huang H, Shi X, Feng L, Lin D, Jiang B, Li Q
eLife 2023 Oct 30;12
eLife 2023 Oct 30;12
Hyodeoxycholic acid alleviates non-alcoholic fatty liver disease through modulating the gut-liver axis.
Kuang J, Wang J, Li Y, Li M, Zhao M, Ge K, Zheng D, Cheung KCP, Liao B, Wang S, Chen T, Zhang Y, Wang C, Ji G, Chen P, Zhou H, Xie C, Zhao A, Jia W, Zheng X, Jia W
Cell metabolism 2023 Oct 3;35(10):1752-1766.e8
Cell metabolism 2023 Oct 3;35(10):1752-1766.e8
Icaritin ameliorates RANKL-mediated osteoclastogenesis and ovariectomy-induced osteoporosis.
Huang JM, Wang Z, Qi GB, Lai Q, Jiang AL, Zhang YQ, Chen K, Wang XH
Aging 2023 Oct 3;15(19):10213-10236
Aging 2023 Oct 3;15(19):10213-10236
Xue-Jie-San prevents the early development of colitis-associated intestinal fibrosis by blocking Notch1 and FGL1 signaling pathways.
Gao Y, Lu LJ, Zhang ZZ, Yang X, Du J, Wen K, Huang H, Wang XP, Sun XL
Journal of ethnopharmacology 2023 Oct 28;315:116678
Journal of ethnopharmacology 2023 Oct 28;315:116678
FTZ promotes islet β-cell regeneration in T1DM mice via the regulation of nuclear proliferation factors.
Zhong Q, Yin J, Wang K, Chen X, Wang H, Hu X, Wang W, Wang L, Bei W, Guo J
Journal of ethnopharmacology 2023 Oct 28;315:116564
Journal of ethnopharmacology 2023 Oct 28;315:116564
Therapeutic Effect of Prolyl Endopeptidase Inhibitor in High-fat Diet-induced Metabolic Dysfunction-associated Fatty Liver Disease.
Zhang JB, Li MT, Lin SZ, Cheng YQ, Fan JG, Chen YW
Journal of clinical and translational hepatology 2023 Oct 28;11(5):1035-1049
Journal of clinical and translational hepatology 2023 Oct 28;11(5):1035-1049
The arginine methyltransferase Prmt1 coordinates the germline arginine methylome essential for spermatogonial homeostasis and male fertility.
Azhar M, Xu C, Jiang X, Li W, Cao Y, Zhu X, Xing X, Wu L, Zou J, Meng L, Cheng Y, Han W, Bao J
Nucleic acids research 2023 Oct 27;51(19):10428-10450
Nucleic acids research 2023 Oct 27;51(19):10428-10450
Unraveling the role of ZNF506 as a human PBS-pro-targeting protein for ERVP repression.
Wu Q, Fang L, Wang Y, Yang P
Nucleic acids research 2023 Oct 27;51(19):10309-10325
Nucleic acids research 2023 Oct 27;51(19):10309-10325
The potential of swine pseudorabies virus attenuated vaccine for oncolytic therapy against malignant tumors.
Wang G, Cao J, Gui M, Huang P, Zhang L, Qi R, Chen R, Lin L, Han Q, Lin Y, Chen T, He P, Ma J, Fu R, Hong J, Wu Q, Yu H, Chen J, Huang C, Zhang T, Yuan Q, Zhang J, Chen Y, Xia N
Journal of experimental & clinical cancer research : CR 2023 Oct 27;42(1):284
Journal of experimental & clinical cancer research : CR 2023 Oct 27;42(1):284
LncRNA PART1 Regulates Ovarian Carcinoma Development via the miR-150-5p/MYB Axis.
Wang J, Han Y, Zhang T, Li J, Xu B
Frontiers in bioscience (Landmark edition) 2023 Oct 27;28(10):270
Frontiers in bioscience (Landmark edition) 2023 Oct 27;28(10):270
N6-methyladenosine-modified oncofetal lncRNA MIR4435-2HG contributed to stemness features of hepatocellular carcinoma cells by regulating rRNA 2'-O methylation.
Zhu Y, Xiao B, Liu M, Chen M, Xia N, Guo H, Huang J, Liu Z, Wang F
Cellular & molecular biology letters 2023 Oct 27;28(1):89
Cellular & molecular biology letters 2023 Oct 27;28(1):89
METTL3-regulated m6A modification impairs the decidualization of endometrial stromal cells by regulating YTHDF2-mediated degradation of FOXO1 mRNA in endometriosis-related infertility.
Li X, Jin J, Long X, Weng R, Xiong W, Liang J, Liu J, Sun J, Cai X, Zhang L, Liu Y
Reproductive biology and endocrinology : RB&E 2023 Oct 27;21(1):99
Reproductive biology and endocrinology : RB&E 2023 Oct 27;21(1):99
N6-methyladenosine demethylase FTO related to hyperandrogenism in PCOS via AKT pathway.
Jing YX, Li HX, Yue F, Li YM, Yu X, He JJ, Zhang XH
Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 2023 Oct 26;39(1):2276167
Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 2023 Oct 26;39(1):2276167
Neurovascular protection of alisol A on cerebral ischemia mice through activating the AKT/GSK3β pathway.
Li H, Zhang C, Zhou Y, Deng Y, Zheng X, Xue X
Aging 2023 Oct 26;15(20):11639-11653
Aging 2023 Oct 26;15(20):11639-11653
Arsenic Exposure-Induced Acute Kidney Injury by Regulating SIRT1/PINK1/Mitophagy Axis in Mice and in HK-2 Cells.
Liu S, Liu Y, Li J, Wang M, Chen X, Gan F, Wen L, Huang K, Liu D
Journal of agricultural and food chemistry 2023 Oct 25;71(42):15809-15820
Journal of agricultural and food chemistry 2023 Oct 25;71(42):15809-15820
FAM111B Acts as an Oncogene in Bladder Cancer.
Huang N, Peng L, Yang J, Li J, Zhang S, Sun M
Cancers 2023 Oct 24;15(21)
Cancers 2023 Oct 24;15(21)
ZDHHC9: a promising therapeutic target for triple-negative breast cancer through immune modulation and immune checkpoint blockade resistance.
Xu C, Xie Y, Xie P, Li J, Tong Z, Yang Y
Discover oncology 2023 Oct 24;14(1):191
Discover oncology 2023 Oct 24;14(1):191
Signaling protein abundance modulates the strength of the spindle assembly checkpoint.
Jema S, Chen C, Humphrey L, Karmarkar S, Ferrari F, Joglekar AP
Current biology : CB 2023 Oct 23;33(20):4505-4515.e4
Current biology : CB 2023 Oct 23;33(20):4505-4515.e4
Acteoside protects podocyte against apoptosis through regulating AKT/GSK-3β signaling pathway in db/db mice.
Li X, Liu Z, He Z, Wang X, Li R, Wang J, Ma G, Zhang P, Ma C
BMC endocrine disorders 2023 Oct 23;23(1):230
BMC endocrine disorders 2023 Oct 23;23(1):230
Soluble TREM2 ameliorates tau phosphorylation and cognitive deficits through activating transgelin-2 in Alzheimer's disease.
Zhang X, Tang L, Yang J, Meng L, Chen J, Zhou L, Wang J, Xiong M, Zhang Z
Nature communications 2023 Oct 21;14(1):6670
Nature communications 2023 Oct 21;14(1):6670
The ubiquitin E3 ligase MDM2 induces chemoresistance in colorectal cancer by degradation of ING3.
Zhang L, Zhu D, Jiang J, Min Z, Fa Z
Carcinogenesis 2023 Oct 20;44(7):562-575
Carcinogenesis 2023 Oct 20;44(7):562-575
GDF15 deficiency hinders human trophoblast invasion to mediate pregnancy loss through downregulating Smad1/5 phosphorylation.
Zeng YT, Liu WF, Zheng PS, Li S
iScience 2023 Oct 20;26(10):107902
iScience 2023 Oct 20;26(10):107902
Neuroepithelial cell-transforming 1 promotes cardiac fibrosis via the Wnt/β-catenin signaling pathway.
Li T, Xiong X, Wang Y, Li Y, Liu Y, Zhang M, Li C, Yu T, Cao W, Chen S, Zhang H, Wang X, Lv L, Zhou Y, Liang H, Li X, Shan H
iScience 2023 Oct 20;26(10):107888
iScience 2023 Oct 20;26(10):107888
Spinal TAOK2 contributes to neuropathic pain via cGAS-STING activation in rats.
Zhang H, Li A, Liu YF, Sun ZM, Jin BX, Lin JP, Yang Y, Yao YX
iScience 2023 Oct 20;26(10):107792
iScience 2023 Oct 20;26(10):107792
Immunoglobulin G inhibits glucocorticoid-induced osteoporosis through occupation of FcγRI.
Jiang L, Qiu W, Wang X, Duan X, Han X, Yu T, Wen S, Luo Z, Feng R, Teng Y, Yin H, Hedrich CM, Deng GM
iScience 2023 Oct 20;26(10):107749
iScience 2023 Oct 20;26(10):107749
LncRNA AGPG Confers Endocrine Resistance in Breast Cancer by Promoting E2F1 Activity.
Yu S, Wang Y, Gong X, Fan Z, Wang Z, Liang Z, Wu R, Cao B, Wang N, Bi C, Lv D, Sun H
Cancer research 2023 Oct 2;83(19):3220-3236
Cancer research 2023 Oct 2;83(19):3220-3236
Intranasal inoculation of female BALB/c mice with replication-deficient human adenovirus type 5 expressing SARS-CoV-2 nucleocapsid protein aggravates lung pathology upon re-encountering the antigen.
Cao J, Gu H, Zhang X, Yun H, Li J, Si CY, Zhang J, Wang H
Virus research 2023 Oct 2;335:199201
Virus research 2023 Oct 2;335:199201
Subconjunctival injection of human umbilical cord mesenchymal stem cells alleviates experimental allergic conjunctivitis via regulating T cell response.
Li D, Ou Q, Shen Q, Lu MM, Xu JY, Jin C, Gao F, Wang J, Zhang J, Zhang J, Li J, Lu L, Xu GT, Tian H
Stem cell research & therapy 2023 Oct 2;14(1):281
Stem cell research & therapy 2023 Oct 2;14(1):281
ER-associated degradation in cystinosis pathogenesis and the prospects of precision medicine.
Venkatarangan V, Zhang W, Yang X, Thoene J, Hahn SH, Li M
The Journal of clinical investigation 2023 Oct 2;133(19)
The Journal of clinical investigation 2023 Oct 2;133(19)
Polydatin improves vascular endothelial function by maintaining mitochondrial homeostasis under high glucose conditions.
Shah W, Zhao Q, Wang S, Zhang M, Ma H, Guan Y, Zhang Y, Liu Y, Zhu C, Wang S, Zhang X, Dong J, Ma H
Scientific reports 2023 Oct 2;13(1):16550
Scientific reports 2023 Oct 2;13(1):16550
Identification of KLHDC2 as an efficient proximity-induced degrader of K-RAS, STK33, β-catenin, and FoxP3.
Röth S, Kocaturk NM, Sathyamurthi PS, Carton B, Watt M, Macartney TJ, Chan KH, Isidro-Llobet A, Konopacka A, Queisser MA, Sapkota GP
Cell chemical biology 2023 Oct 19;30(10):1261-1276.e7
Cell chemical biology 2023 Oct 19;30(10):1261-1276.e7
Substrate-dependent interaction of SPOP and RACK1 aggravates cardiac fibrosis following myocardial infarction.
Yang W, Zhuang Y, Wu H, Su S, Li Y, Wang C, Tian Z, Peng L, Zhang X, Liu J, Pei X, Yuan W, Hu X, Meng B, Li D, Zhang Y, Shan H, Pan Z, Lu Y
Cell chemical biology 2023 Oct 19;30(10):1248-1260.e4
Cell chemical biology 2023 Oct 19;30(10):1248-1260.e4
Vitisin A, as a Type of Pyranoanthocyanin, Suppresses Inflammation by Restricting Hematopoietic Stem Cell Differentiation toward Monocytes in Bone Marrow.
Li X, Li Z, Cai D, Li Y, Zhu Y, Jiao R, Lai C, Sun J, Bai W
Journal of agricultural and food chemistry 2023 Oct 18;71(41):15048-15063
Journal of agricultural and food chemistry 2023 Oct 18;71(41):15048-15063
Screening and verifying the mutations in the LDLR and APOB genes in a Chinese family with familial hypercholesterolemia.
Lv X, Wang C, Liu L, Yin G, Zhang W, Abdu FA, Shi T, Zhang Q, Che W
Lipids in health and disease 2023 Oct 18;22(1):175
Lipids in health and disease 2023 Oct 18;22(1):175
C3aR Antagonist Alleviates C3a Induced Tubular Profibrotic Phenotype Transition via Restoring PPARα/CPT-1α Mediated Mitochondrial Fatty Acid Oxidation in Renin-Dependent Hypertension.
Wang C, Wang Z, Xu J, Ma H, Jin K, Xu T, Pan X, Feng X, Zhang W
Frontiers in bioscience (Landmark edition) 2023 Oct 17;28(10):238
Frontiers in bioscience (Landmark edition) 2023 Oct 17;28(10):238
Exosomal Linc00969 induces trastuzumab resistance in breast cancer by increasing HER-2 protein expression and mRNA stability by binding to HUR.
Liu C, Lu C, Yixi L, Hong J, Dong F, Ruan S, Hu T, Zhao X
Breast cancer research : BCR 2023 Oct 17;25(1):124
Breast cancer research : BCR 2023 Oct 17;25(1):124
Proximal Tubular Lats2 Ablation Exacerbates Ischemia/Reperfusion Injury (IRI)-Induced Renal Maladaptive Repair through the Upregulation of P53.
Zhang C, Zheng Z, Xu K, Cheng G, Wu H, Liu J
International journal of molecular sciences 2023 Oct 17;24(20)
International journal of molecular sciences 2023 Oct 17;24(20)
KHDRBS3 accelerates glycolysis and promotes malignancy of hepatocellular carcinoma via upregulating 14-3-3ζ.
Zhao M, Zhang Y, Li L, Liu X, Zhou W, Wang C, Tang Y
Cancer cell international 2023 Oct 17;23(1):244
Cancer cell international 2023 Oct 17;23(1):244
The HNF4A-CHPF pathway promotes proliferation and invasion through interactions with MAD1L1 in glioma.
Luo H, Huang K, Cheng M, Long X, Zhu X, Wu M
Aging 2023 Oct 17;15(20):11052-11066
Aging 2023 Oct 17;15(20):11052-11066
MafB regulates NLRP3 inflammasome activation by sustaining p62 expression in macrophages.
Cui H, Banerjee S, Xie N, Dey T, Liu RM, Sanders YY, Liu G
Communications biology 2023 Oct 16;6(1):1047
Communications biology 2023 Oct 16;6(1):1047
PI3K/mTOR inhibitor VS-5584 combined with PLK1 inhibitor exhibits synergistic anti-cancer effects on non-small cell lung cancer.
Zhao S, Li Y, Li G, Ye J, Wang R, Zhang X, Li F, Gao C, Li J, Jiang J, Mi Y
European journal of pharmacology 2023 Oct 15;957:176004
European journal of pharmacology 2023 Oct 15;957:176004
URB597 exerts neuroprotective effects against transient brain ischemia injury in mice by regulating autophagic flux and necroptosis.
Yuan X, Ye W, Chen L, Luo D, Zhou L, Qiu Y, Zhuo R, Zhao Y, Peng L, Yang L, Jin X, Zhou Y
European journal of pharmacology 2023 Oct 15;957:175982
European journal of pharmacology 2023 Oct 15;957:175982
The novel peptide athycaltide-1 attenuates Ang II-induced pathological myocardial hypertrophy by reducing ROS and inhibiting the activation of CaMKII and ERK1/2.
Zheng X, Su F, Lei M, Li J, Zhang C, Zhang Y, Wei M, Li W, Chen S, Liu Y, Gao Q, Hao L
European journal of pharmacology 2023 Oct 15;957:175969
European journal of pharmacology 2023 Oct 15;957:175969
FAM134B-induced endoplasmic reticulum (ER)-phagy exacerbates cisplatin-insulted hair cell apoptosis ：Possible relation to excessive ER stress.
Yang H, Yin H, Wang Y, Liu J, Guo L, Zhao H, Bai X, Li J, Yang Q
Archives of biochemistry and biophysics 2023 Oct 15;748:109766
Archives of biochemistry and biophysics 2023 Oct 15;748:109766
DnaJA2 interacts with Japanese encephalitis virus NS3 via its C-terminal to promote viral infection.
Qin L, Rao T, Li X, Chen H, Qian P
Virus research 2023 Oct 15;336:199210
Virus research 2023 Oct 15;336:199210
Mutation of the ETS1 3'UTR interacts with miR-216a-3p to regulate granulosa cell apoptosis in sheep.
Yang F, Liu Y, Wang P, Wang X, Chu M, Wang P
Theriogenology 2023 Oct 15;210:133-142
Theriogenology 2023 Oct 15;210:133-142
TSG-6 alleviates cerebral ischemia/reperfusion injury and blood-brain barrier disruption by suppressing ER stress-mediated inflammation.
Cui S, Ke L, Wang H, Li L
Brain research 2023 Oct 15;1817:148466
Brain research 2023 Oct 15;1817:148466
The cryo-EM structure of the human ERAD retrotranslocation complex.
Rao B, Wang Q, Yao D, Xia Y, Li W, Xie Y, Li S, Cao M, Shen Y, Qin A, Zhao J, Cao Y
Science advances 2023 Oct 13;9(41):eadi5656
Science advances 2023 Oct 13;9(41):eadi5656
Dysregulated expression of slingshot protein phosphatase 1 (SSH1) disrupts circadian rhythm and WNT signaling associated to hepatocellular carcinoma pathogenesis.
Lai SW, Cheng YC, Huang WC, Yadav VK, Fong IH, Yeh CT, Yang CK, Lee WH, Chen MY
Aging 2023 Oct 13;15(20):11033-11051
Aging 2023 Oct 13;15(20):11033-11051
Mechanism of BLIMP1/TRIM66/COX2 in human decidua participates in parturition†.
Zhou W, Geng H, Huang Y, Shi S, Wang Z, Wang D
Biology of reproduction 2023 Oct 13;109(4):507-519
Biology of reproduction 2023 Oct 13;109(4):507-519
Network pharmacology-based strategy for predicting therapy targets of Ecliptae Herba on breast cancer.
Li H, Shi W, Shen T, Hui S, Hou M, Wei Z, Qin S, Bai Z, Cao J
Medicine 2023 Oct 13;102(41):e35384
Medicine 2023 Oct 13;102(41):e35384
Jin-Gui-Shen-Qi Wan ameliorates diabetic retinopathy by inhibiting apoptosis of retinal ganglion cells through the Akt/HIF-1α pathway.
Liang D, Qi Y, Liu L, Chen Z, Tang S, Tang J, Chen N
Chinese medicine 2023 Oct 12;18(1):130
Chinese medicine 2023 Oct 12;18(1):130
Micheliolide prevents estrogen deficiency-induced bone loss via inhibiting osteoclast bone resorption.
Gan Z, Huang J, Xu M, Yuan X, Shang X, Chen X, Chen K
Aging 2023 Oct 11;15(19):10732-10745
Aging 2023 Oct 11;15(19):10732-10745
Two polysaccharides from Rehmannia glutinosa: isolation, structural characterization, and hypoglycemic activities.
Chen H, Liu X, Xie M, Zhong X, Yan C, Xian M, Wang S
RSC advances 2023 Oct 11;13(43):30190-30201
RSC advances 2023 Oct 11;13(43):30190-30201
Disabled-2: a protein up-regulated by high molecular weight hyaluronan has both tumor promoting and tumor suppressor roles in ovarian cancer.
Price ZK, Lokman NA, Sugiyama M, Koya Y, Yoshihara M, Oehler MK, Kajiyama H, Ricciardelli C
Cellular and molecular life sciences : CMLS 2023 Oct 10;80(11):320
Cellular and molecular life sciences : CMLS 2023 Oct 10;80(11):320
The ATF2/miR-3913-5p/CREB5 axis is involved in the cell proliferation and metastasis of colorectal cancer.
Dai W, Hong L, Xiao W, Zhang L, Sha W, Yu Z, Liu X, Liu S, Xiao Y, Yang P, Peng Y, Zhang J, Lin J, Wu X, Tang W, Lin Z, Xiang L, Li J, Pei M, Wang J
Communications biology 2023 Oct 10;6(1):1026
Communications biology 2023 Oct 10;6(1):1026
Astragalus polysaccharide restores insulin secretion impaired by lipopolysaccharides through the protein kinase B /mammalian target of rapamycin/glucose transporter 2 pathway.
Ren X, Dai Y, Shan M, Zheng J, Zhang Z, Shen T
BMC complementary medicine and therapies 2023 Oct 10;23(1):358
BMC complementary medicine and therapies 2023 Oct 10;23(1):358
CSTF2 mediated mRNA N(6)-methyladenosine modification drives pancreatic ductal adenocarcinoma m(6)A subtypes.
Zheng Y, Li X, Deng S, Zhao H, Ye Y, Zhang S, Huang X, Bai R, Zhuang L, Zhou Q, Li M, Su J, Li R, Bao X, Zeng L, Chen R, Zheng J, Lin D, He C, Zhang J, Zuo Z
Nature communications 2023 Oct 10;14(1):6334
Nature communications 2023 Oct 10;14(1):6334
Molecular mechanism by which RRM2-inhibitor (cholagogue osalmid) plus bafilomycin A1 cause autophagic cell death in multiple myeloma.
Guo S, Xu Z, Feng Q, Zhang H, Yu D, Li B, Hu K, Gao X, Zhang Q, Yi H, Wu X, Song D, Zhu H, Cai H, Peng Y, Zhu W, Shi J
Archives of biochemistry and biophysics 2023 Oct 1;747:109771
Archives of biochemistry and biophysics 2023 Oct 1;747:109771
MICALL2 participates in the regulation of epithelial-mesenchymal transition in alveolar epithelial cells - Potential roles in pulmonary fibrosis.
Chen Y, Song W, Zhang H, Ji X
Archives of biochemistry and biophysics 2023 Oct 1;747:109730
Archives of biochemistry and biophysics 2023 Oct 1;747:109730
Sorafenib induces ferroptosis by promoting TRIM54-mediated FSP1 ubiquitination and degradation in hepatocellular carcinoma.
Liu MR, Shi C, Song QY, Kang MJ, Jiang X, Liu H, Pei DS
Hepatology communications 2023 Oct 1;7(10)
Hepatology communications 2023 Oct 1;7(10)
miR-552 promotes the proliferation and metastasis of intrahepatic cholangiocarcinoma by targeting FOXO1.
Cheng Z, Cheng N, Tang X, Yang F, Ma W, Yu Q, Tang H, Xiao Q, Lei Z
Experimental cell research 2023 Oct 1;431(1):113741
Experimental cell research 2023 Oct 1;431(1):113741
DEPDC1B-mediated USP5 deubiquitination of β-catenin promotes breast cancer metastasis by activating the wnt/β-catenin pathway.
Wang Q, Chen F, Yang N, Xu L, Yu X, Wu M, Zhou Y
American journal of physiology. Cell physiology 2023 Oct 1;325(4):C833-C848
American journal of physiology. Cell physiology 2023 Oct 1;325(4):C833-C848
Complement C1q drives microglia-dependent synaptic loss and cognitive impairments in a mouse model of lipopolysaccharide-induced neuroinflammation.
Wu X, Gao Y, Shi C, Tong J, Ma D, Shen J, Yang J, Ji M
Neuropharmacology 2023 Oct 1;237:109646
Neuropharmacology 2023 Oct 1;237:109646
Comparative multi-omic analyses of cardiac mitochondrial stress in three mouse models of frataxin deficiency.
Sayles NM, Napierala JS, Anrather J, Diedhiou N, Li J, Napierala M, Puccio H, Manfredi G
Disease models & mechanisms 2023 Oct 1;16(10)
Disease models & mechanisms 2023 Oct 1;16(10)
CNTN1 Aggravates Neuroinflammation and Triggers Cognitive Deficits in Male Mice by Boosting Crosstalk between Microglia and Astrocytes.
Li SJ, Ma MH, Li JM, Lu XY, Lu CB, Zhou SF, Zhang LX, Li MQ, Shao TZ, Bai SP, Yan XX, Li F, Li CQ
Aging and disease 2023 Oct 1;14(5):1853-1869
Aging and disease 2023 Oct 1;14(5):1853-1869
Pharmacokinetic and pharmacodynamic drug-drug interaction of Nomilin with atorvastatin in hyperlipidemic mice.
Ding Y, Guan H, Yan Y, Chen Y, Huang C
Heliyon 2023 Nov;9(11):e22016
Heliyon 2023 Nov;9(11):e22016
Dendrobium mixture ameliorates hepatic injury induced by insulin resistance in vitro and in vivo through the downregulation of AGE/RAGE/Akt signaling pathway.
Zhuang S, Zhou X, Yang X, Chang D, Chen T, Sun Y, Wang C, Zhang C, Jiang J, Chen Y, Lin X, Wang X, Yu W, Lin X, He C, Zheng Y, Zhang J, Shi H
Heliyon 2023 Nov;9(11):e22007
Heliyon 2023 Nov;9(11):e22007
Icariin promotes osteogenic differentiation through the mmu_circ_0000349/mmu-miR-138-5p/Jumonji domain-containing protein-3 axis.
Ai L, Chen L, Tao Y, Wang H, Yi W
Heliyon 2023 Nov;9(11):e21885
Heliyon 2023 Nov;9(11):e21885
Exploring the anticancer potential of Actinidia chinensis Planch root extracts (acRoots) on hepatocellular carcinoma: A molecular mechanism study.
Qiu K, Xia Q, Chen H, Ye Q, Mao H, Tian M, Gan Y, Huang Q, Wang H, Duan S
Heliyon 2023 Nov;9(11):e21851
Heliyon 2023 Nov;9(11):e21851
Korean red ginseng formula attenuates non-alcoholic fatty liver disease in oleic acid-induced HepG2 cells and high-fat diet-induced rats.
Zheng M, Li Y, Dong Z, Zhang Y, Xi Z, Yuan M, Xu H
Heliyon 2023 Nov;9(11):e21846
Heliyon 2023 Nov;9(11):e21846
LncBIRC3-OT promotes the malignant progression of glioma by interacting with RELA to upregulate stanniocalcin-1 expression.
Wang R, Li Q, Chu X, Li N, Liang H, He F
Heliyon 2023 Nov;9(11):e21777
Heliyon 2023 Nov;9(11):e21777
Network pharmacology and in vitro experimental verification to reveal the mechanism of Astragaloside IV against kidney ischemia-reperfusion injury.
Guo Y, Wang J, Hua Y, Jiang M, Xu W, Shi Y, Yang J, Wan H, Yang R
Heliyon 2023 Nov;9(11):e21711
Heliyon 2023 Nov;9(11):e21711
Multi-omics reveals aging-related pathway in natural aging mouse liver.
Tang CM, Zhang Z, Sun Y, Ding WJ, Yang XC, Song YP, Ling MY, Li XH, Yan R, Zheng YJ, Yu N, Zhang WH, Wang Y, Wang SP, Gao HQ, Zhao CL, Xing YQ
Heliyon 2023 Nov;9(11):e21011
Heliyon 2023 Nov;9(11):e21011
Rab11-FIP4 interacts with ARF5 to promote cancer stemness in hepatocellular carcinoma.
Song F, Zhang Q, Lu X, Xu T, Hu Q, Hu X, Fan W, Zhang Y, Huang P
Journal of physiology and biochemistry 2023 Nov;79(4):757-770
Journal of physiology and biochemistry 2023 Nov;79(4):757-770
Agaricus blazei Murrill Polysaccharide Attenuates Periodontitis via H(2) S/NRF2 Axis-Boosted Appropriate Level of Autophagy in PDLCs.
Yuan W, Huang M, Wu Y, Liu J, Zhou X, Wang J, Liu J
Molecular nutrition & food research 2023 Nov;67(22):e2300112
Molecular nutrition & food research 2023 Nov;67(22):e2300112
ADAR1 exacerbates ischemic brain injury via astrocyte-mediated neuron apoptosis.
Cai D, Fraunfelder M, Fujise K, Chen SY
Redox biology 2023 Nov;67:102903
Redox biology 2023 Nov;67:102903
Antimicrobial agent chloroxylenol targets β‑catenin‑mediated Wnt signaling and exerts anticancer activity in colorectal cancer.
Sun Q, Liu B, Lan Q, Su Z, Fu Q, Wang L, Deng Y, Li C, Xue VW, Liu S, Chen X, Yang G, Lu D
International journal of oncology 2023 Nov;63(5)
International journal of oncology 2023 Nov;63(5)
LKB1 loss promotes colorectal cancer cell metastasis through regulating TNIK expression and actin cytoskeleton remodeling.
Hu G, Huang N, Zhang J, Zhang D, Wang S, Zhang Y, Wang L, Du Y, Kuang S, Ma K, Zhu H, Xu N, Liu M
Molecular carcinogenesis 2023 Nov;62(11):1659-1672
Molecular carcinogenesis 2023 Nov;62(11):1659-1672
Macrophage microvesicle-derived circ_YTHDF2 in methamphetamine-induced chronic lung injury.
Chen L, Gu YJ, Zhang XG, Cheng L, Zhou MY, Yang Y, Wang Y
The Journal of physiology 2023 Nov;601(22):5107-5128
The Journal of physiology 2023 Nov;601(22):5107-5128
BMP4 Regulates EMT to be Involved in non-Syndromic Cleft lip With or Without Palate.
Hong JW, Yu Y, Wang LS, Li Z, Zhang R, Wang Q, Ding Z, Zhang JP, Zhang MR, Xu LC
The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association 2023 Nov;60(11):1462-1473
The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association 2023 Nov;60(11):1462-1473
Inhibition of the SREBP pathway prevents SARS-CoV-2 replication and inflammasome activation.
Soares VC, Dias SSG, Santos JC, Azevedo-Quintanilha IG, Moreira IBG, Sacramento CQ, Fintelman-Rodrigues N, Temerozo JR, da Silva MAN, Barreto-Vieira DF, Souza TM, Bozza PT
Life science alliance 2023 Nov;6(11)
Life science alliance 2023 Nov;6(11)
RACK1 promotes porcine reproductive and respiratory syndrome virus infection in Marc-145 cells through ERK1/2 activation.
Wang X, Bi J, Yang Y, Li L, Zhang R, Li Y, Cheng M, Li W, Yang G, Lin Y, Liu J, Yin G
Virology 2023 Nov;588:109886
Virology 2023 Nov;588:109886
Suppression of the gut microbiota-bile acid-FGF19 axis in patients with atrial fibrillation.
Zuo K, Fang C, Gao Y, Fu Y, Wang H, Li J, Zhong J, Yang X, Xu L
Cell proliferation 2023 Nov;56(11):e13488
Cell proliferation 2023 Nov;56(11):e13488
Characterization of circRNAs in established osimertinib‑resistant non‑small cell lung cancer cell lines.
Chen X, Gu J, Huang J, Wen K, Zhang G, Chen Z, Wang Z
International journal of molecular medicine 2023 Nov;52(5)
International journal of molecular medicine 2023 Nov;52(5)
ATG7-mediated autophagy protects human gingival myofibroblasts from irradiation-induced apoptosis.
Zhuang X, Lin X, Xu R, Zhang Z, Zhou B, Deng F
Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology 2023 Nov;52(10):996-1003
Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology 2023 Nov;52(10):996-1003
Electroacupuncture Ameliorates Hypothalamic‒Pituitary‒Adrenal Axis Dysfunction Induced by Surgical Trauma in Mice Through the Hypothalamic Oxytocin System.
Wu F, Zhu J, Wan Y, Subinuer Kurexi, Zhou J, Wang K, Chen T
Neurochemical research 2023 Nov;48(11):3391-3401
Neurochemical research 2023 Nov;48(11):3391-3401
Inhibition of TMEM16A improves cisplatin-induced acute kidney injury via preventing DRP1-mediated mitochondrial fission.
Li XL, Liu XW, Liu WL, Lin YQ, Liu J, Peng YS, Cheng LM, Du YH
Acta pharmacologica Sinica 2023 Nov;44(11):2230-2242
Acta pharmacologica Sinica 2023 Nov;44(11):2230-2242
Targeting histone deacetylase suppresses tumor growth through eliciting METTL14-modified m(6) A RNA methylation in ocular melanoma.
Zhuang A, Gu X, Ge T, Wang S, Ge S, Chai P, Jia R, Fan X
Cancer communications (London, England) 2023 Nov;43(11):1185-1206
Cancer communications (London, England) 2023 Nov;43(11):1185-1206
Blockade of de novo pyrimidine biosynthesis triggers autophagic degradation of oncoprotein FLT3-ITD in acute myeloid leukemia.
Ma H, Cui J, Liu Z, Fang W, Lu S, Cao S, Zhang Y, Chen JA, Lu L, Xie Q, Wang Y, Huang Y, Li K, Tong H, Huang J, Lu W
Oncogene 2023 Nov;42(45):3331-3343
Oncogene 2023 Nov;42(45):3331-3343
Orientin inhibits inflammation in chondrocytes and attenuates osteoarthritis through Nrf2/NF-κB and SIRT6/NF-κB pathway.
Xia W, Xiao J, Tong C, Lu J, Tu Y, Li S, Ni L, Shi Y, Luo P, Zhang X, Wang X
Journal of orthopaedic research : official publication of the Orthopaedic Research Society 2023 Nov;41(11):2405-2417
Journal of orthopaedic research : official publication of the Orthopaedic Research Society 2023 Nov;41(11):2405-2417
Protective effect of liriodendrin on IgG immune complex-induced acute lung injury via inhibiting SRC/STAT3/MAPK signaling pathway: a network pharmacology research.
Zhang S, Hu D, Zhuo Y, Cui L, Li D, Zhang L, Yang L, Wang X
Naunyn-Schmiedeberg's archives of pharmacology 2023 Nov;396(11):3269-3283
Naunyn-Schmiedeberg's archives of pharmacology 2023 Nov;396(11):3269-3283
Epinodosin suppresses the proliferation, invasion, and migration of esophageal squamous cell carcinoma by mediating miRNA-143-3p/Bcl-2 axis.
Chen H, Li Y, Liu Y, Zhao Y, Xu F, Yang S, Yu M, Zou M, Zhang J
Phytotherapy research : PTR 2023 Nov;37(11):5378-5393
Phytotherapy research : PTR 2023 Nov;37(11):5378-5393
IGF2BP3 drives gallbladder cancer progression by m6A-modified CLDN4 and inducing macrophage immunosuppressive polarization.
Qin J, Cui Z, Zhou J, Zhang B, Lu R, Ding Y, Hu H, Cai J
Translational oncology 2023 Nov;37:101764
Translational oncology 2023 Nov;37:101764
Rac GTPase activating protein 1 promotes the glioma growth by regulating the expression of MCM3.
Jia B, Jiang Y, Huan Y, Han Y, Liu W, Liu X, Wang Y, He L, Cao Z, He X, Zhang K, Gu J, Guo Q, Fei Z
Translational oncology 2023 Nov;37:101756
Translational oncology 2023 Nov;37:101756
C-IGF1R encoded by cIGF1R acts as a molecular switch to restrict mitophagy of drug-tolerant persister tumour cells in non-small cell lung cancer.
Wang H, Liang Y, Zhang T, Yu X, Song X, Chen Y, Mao Q, Xia W, Chen B, Xu L, Dong G, Jiang F
Cell death and differentiation 2023 Nov;30(11):2365-2381
Cell death and differentiation 2023 Nov;30(11):2365-2381
SATB1 promotes osteogenic differentiation of diabetic rat BMSCs through MAPK signalling activation.
Guo J, Chen Z, Xiao Y, Yu G, Li Y
Oral diseases 2023 Nov;29(8):3610-3619
Oral diseases 2023 Nov;29(8):3610-3619
Curcumin nanoemulsions inhibit oral squamous cell carcinoma cell proliferation by PI3K/Akt/mTOR suppression and miR-199a upregulation: A preliminary study.
Liu W, Wang J, Zhang C, Bao Z, Wu L
Oral diseases 2023 Nov;29(8):3183-3192
Oral diseases 2023 Nov;29(8):3183-3192
Pregnane X receptor (PXR) deficiency protects against spinal cord injury by activating NRF2/HO-1 pathway.
Xuan LN, Hu ZX, Jiang ZF, Zhang C, Sun XW, Ming WH, Liu HT, Qiao RF, Shen LJ, Liu SB, Wang GY, Wen L, Luan ZL, Yin J
CNS neuroscience & therapeutics 2023 Nov;29(11):3460-3478
CNS neuroscience & therapeutics 2023 Nov;29(11):3460-3478
RBM25 regulates hypoxic cardiomyocyte apoptosis through CHOP-associated endoplasmic reticulum stress.
Zhu Z, Pu J, Li Y, Chen J, Ding H, Zhou A, Zhang X
Cell stress & chaperones 2023 Nov;28(6):861-876
Cell stress & chaperones 2023 Nov;28(6):861-876
HIF‑1α and RACGAP1 promote the progression of hepatocellular carcinoma in a mutually regulatory way.
Wu X, Xu Z, Li W, Lu Y, Pu J
Molecular medicine reports 2023 Nov;28(5)
Molecular medicine reports 2023 Nov;28(5)
Enrofloxacin hydrochloride toxicological effects on crucian carp reflected by serological changes and neurotoxicity.
Wan G, Huang J, Wang R, Liu H, Wei L, Liang X, Li F, Wang Z, Gu X, Ruan J
Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 2023 Nov;273:109737
Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 2023 Nov;273:109737
Mulberrin alleviates triclocarban induced hepatic apoptosis and inflammation by regulating the ROS/NF-κB pathway in grass carp.
Li S, Xie J, Li K, Bai Y, Jiang Z, Xiong X
Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 2023 Nov;273:109734
Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 2023 Nov;273:109734
Knockdown of Bach1 protects periodontal bone regeneration from inflammatory damage.
Yuan Z, Li J, Zou X, Liu C, Lu J, Ni C, Tang L, Wu X, Yan F
Journal of cellular and molecular medicine 2023 Nov;27(22):3465-3477
Journal of cellular and molecular medicine 2023 Nov;27(22):3465-3477
Autophagy and LC3-associated phagocytosis contribute negatively to the killing capability of THP-1-derived macrophages against Candida albicans at the mid-stage.
Li D, Wang L, Zhao Z, Bai C, Li X
Immunology letters 2023 Nov;263:25-32
Immunology letters 2023 Nov;263:25-32
The ligation between ERMAP, galectin-9 and dectin-2 promotes Kupffer cell phagocytosis and antitumor immunity.
Li J, Liu XG, Ge RL, Yin YP, Liu YD, Lu WP, Huang M, He XY, Wang J, Cai G, Sun SH, Yuan JH
Nature immunology 2023 Nov;24(11):1813-1824
Nature immunology 2023 Nov;24(11):1813-1824
circAP1M2 activates ATG9A-associated autophagy by inhibiting miR-1249-3p to promote cisplatin resistance in oral squamous cell carcinoma.
Wenhao R, Yali C, Shaoming L, Jingjing Z, Ling G, Keqian Z
Journal of cellular physiology 2023 Nov;238(11):2612-2624
Journal of cellular physiology 2023 Nov;238(11):2612-2624
PSMC2 knockdown exerts an anti-tumor role in nasopharyngeal carcinoma through regulating AKT signaling pathway.
Su J, Hu S, Ding S, Feng K
Cell cycle (Georgetown, Tex.) 2023 Nov;22(21-22):2381-2391
Cell cycle (Georgetown, Tex.) 2023 Nov;22(21-22):2381-2391
Dauricine regulates prostate cancer progression by inhibiting PI3K/AKT-dependent M2 polarization of macrophages.
Li M, Che N, Liu X, Xuan Y, Jin Y
Biochemical pharmacology 2023 Nov;217:115838
Biochemical pharmacology 2023 Nov;217:115838
TIPE2 ameliorates neuroinflammation and cognitive impairment in sepsis-associated encephalopathy through regulating RhoA/ROCK2-NF-κB signaling pathway.
Yuan M, Jing G, Kong Q, Ming T, Zuo J, Wang Q, Feng Y, Liu W, Wu X, Xia Z
Biochemical pharmacology 2023 Nov;217:115816
Biochemical pharmacology 2023 Nov;217:115816
The role of miR-199a-3p in inhibiting the proliferation of spermatogonial stem cells under heat stress.
Zhuo L, Zhou Y, Tian J, Li Y, Xie Z, Pei C, Yan B, Ma L
Theriogenology 2023 Nov;211:56-64
Theriogenology 2023 Nov;211:56-64
Ethanol extract of Herpetospermum caudigerum Wall ameliorates psoriasis-like skin inflammation and promotes degradation of keratinocyte-derived ICAM-1 and CXCL9.
Zhong Y, Zhang BW, Li JT, Zeng X, Pei JX, Zhang YM, Yang YX, Li FL, Deng Y, Zhao Q
Journal of integrative medicine 2023 Nov;21(6):584-592
Journal of integrative medicine 2023 Nov;21(6):584-592
Resurrection of 2'-5'-oligoadenylate synthetase 1 (OAS1) from the ancestor of modern horseshoe bats blocks SARS-CoV-2 replication.
Lytras S, Wickenhagen A, Sugrue E, Stewart DG, Swingler S, Sims A, Jackson Ireland H, Davies EL, Ludlam EM, Li Z, Hughes J, Wilson SJ
PLoS biology 2023 Nov;21(11):e3002398
PLoS biology 2023 Nov;21(11):e3002398
Melatonin attenuates sevoflurane-induced hippocampal damage and cognitive deficits in neonatal mice by suppressing CypD in parvalbumin neurons.
Zou X, Zhang X, Qiang T, Hu X, Zhang L
Brain research bulletin 2023 Nov;204:110809
Brain research bulletin 2023 Nov;204:110809
Multi-parametric MRI assessment of melatonin regulating the polarization of microglia in rats after cerebral ischemia/reperfusion injury.
Li Z, Gong P, Zhang M, Li C, Xiao P, Yu M, Wang X, An L, Bi F, Song X, Wang X
Brain research bulletin 2023 Nov;204:110807
Brain research bulletin 2023 Nov;204:110807
Inhibition of ferroptosis alleviates chronic unpredictable mild stress-induced depression in mice via tsRNA-3029b.
Li E, Yin H, Su M, Li Q, Zhao Y, Zhang L, Guo J, Lai X, Xue X, Tang C
Brain research bulletin 2023 Nov;204:110773
Brain research bulletin 2023 Nov;204:110773
Fucoidan promotes angiogenesis and accelerates wound healing through AKT/Nrf2/HIF-1α signalling pathway.
Wen W, Yang L, Wang X, Zhang H, Wu F, Xu K, Chen S, Liao Z
International wound journal 2023 Nov;20(9):3606-3618
International wound journal 2023 Nov;20(9):3606-3618
Sphingosine kinase 1/S1P receptor signaling axis is essential for cellular uptake of Neisseria meningitidis in brain endothelial cells.
Fohmann I, Weinmann A, Schumacher F, Peters S, Prell A, Weigel C, Spiegel S, Kleuser B, Schubert-Unkmeir A
PLoS pathogens 2023 Nov;19(11):e1011842
PLoS pathogens 2023 Nov;19(11):e1011842
Autophagy regulation and protein kinase activity of PIK3C3 controls sertoli cell polarity through its negative regulation on SCIN (scinderin).
Wang K, Kong F, Qiu Y, Chen T, Fu J, Jin X, Su Y, Gu Y, Hu Z, Li J
Autophagy 2023 Nov;19(11):2934-2957
Autophagy 2023 Nov;19(11):2934-2957
Gelation of cytoplasmic expanded CAG RNA repeats suppresses global protein synthesis.
Pan Y, Lu J, Feng X, Lu S, Yang Y, Yang G, Tan S, Wang L, Li P, Luo S, Lu B
Nature chemical biology 2023 Nov;19(11):1372-1383
Nature chemical biology 2023 Nov;19(11):1372-1383
Elaidic acid induced hepatocyte pyroptosis via autophagy-CTSB-NLRP3 pathway.
Lu J, Chen Z, Bu X, Chen S, Guan S
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2023 Nov;181:114060
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2023 Nov;181:114060
The protective effects of EGCG was associated with HO-1 active and microglia pyroptosis inhibition in experimental intracerebral hemorrhage.
Bao B, Yin XP, Wen XQ, Suo YJ, Chen ZY, Li DL, Lai Q, Cao XM, Qu QM
Neurochemistry international 2023 Nov;170:105603
Neurochemistry international 2023 Nov;170:105603
Identifying the personalized driver gene sets maximally contributing to abnormality of transcriptome phenotype in glioblastoma multiforme individuals.
Xu J, Pang B, Lan Y, Dou R, Wang S, Kang S, Zhang W, Liu Y, Zhang Y, Ping Y
Molecular oncology 2023 Nov;17(11):2472-2490
Molecular oncology 2023 Nov;17(11):2472-2490
Cyclovirobuxine D alleviates aldosterone-induced myocardial hypertrophy by protecting mitochondrial function depending on the mutual regulation of Nrf2-SIRT3.
Wang X, Wu H, An J, Zhang G, Chen Y, Fu L, Tao L, Liang G, Shen X
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Nov;167:115618
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Nov;167:115618
Colorectal cancer tissue-originated spheroids reveal tumor intrinsic signaling pathways and mimic patient clinical chemotherapeutic response as a rapid and valid model.
Zhang Y, Huo J, Yu S, Feng W, Tuersun A, Chen F, Lv Z, Liu W, Zhao J, Xu Z, Lu A, Zong Y
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Nov;167:115585
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Nov;167:115585
An oral triple pill-based cocktail effectively controls acute myeloid leukemia with high translation.
Li M, Zheng S, Gong Q, Zhuang H, Wu Z, Wang P, Zhang X, Xu R
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Nov;167:115584
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Nov;167:115584
The novel lncRNA-9802/miR-1646 axis affects cell proliferation of DF-1 by regulating Bax/Bcl-2 signaling pathway.
Han S, Zhao S, Zhao Y, Liu M, Han L, Han L
Research in veterinary science 2023 Nov;164:105047
Research in veterinary science 2023 Nov;164:105047
The role of the Gas6/TAM signal pathway in the LPS-induced pulmonary epithelial cells injury.
Cheng Y, Yang X, Wang Y, Ding Q, Huang Y, Zhang C
Molecular immunology 2023 Nov;163:181-187
Molecular immunology 2023 Nov;163:181-187
A Novel EYA1 Mutation Causing Alternative RNA Splicing in a Chinese Family With Branchio-Oto Syndrome: Implications for Molecular Diagnosis and Clinical Application.
Chen A, Ling J, Peng X, Liu X, Mao S, Chen Y, Qin M, Zhang S, Bai Y, Song J, Feng Z, Ma L, He D, Mei L, He C, Feng Y
Clinical and experimental otorhinolaryngology 2023 Nov;16(4):342-358
Clinical and experimental otorhinolaryngology 2023 Nov;16(4):342-358
The expression and distribution of TACAN in human and rat bladders.
Lu Q, Liu Q, Chen S, Wang J, Chen Y, Sun B, Yang Z, Feng H, Yi S, Chen W, Zhu J
Lower urinary tract symptoms 2023 Nov;15(6):256-264
Lower urinary tract symptoms 2023 Nov;15(6):256-264
Design, synthesis, and biological evaluation of carbonyl-hydrazine-1-carboxamide derivatives as anti-hepatic fibrosis agents targeting Nur77.
Hu H, Lin G, He F, Liu J, Jia R, Li K, Hong W, Fang M, Zeng JZ
Bioorganic chemistry 2023 Nov;140:106795
Bioorganic chemistry 2023 Nov;140:106795
SIRT1 is an actionable target to restore p53 function in HPV-associated cancer therapy.
Lo Cigno I, Calati F, Girone C, Borgogna C, Venuti A, Boldorini R, Gariglio M
British journal of cancer 2023 Nov;129(11):1863-1874
British journal of cancer 2023 Nov;129(11):1863-1874
The heterogeneity of tumour immune microenvironment revealing the CRABP2/CD69 signature discriminates distinct clinical outcomes in breast cancer.
Mei J, Cai Y, Chen L, Wu Y, Liu J, Qian Z, Jiang Y, Zhang P, Xia T, Pan X, Zhang Y
British journal of cancer 2023 Nov;129(10):1645-1657
British journal of cancer 2023 Nov;129(10):1645-1657
GBP2 upregulated in LPS-stimulated macrophages-derived exosomes accelerates septic lung injury by activating epithelial cell NLRP3 signaling.
Huang W, Zhang Y, Zheng B, Ling X, Wang G, Li L, Wang W, Pan M, Li X, Meng Y
International immunopharmacology 2023 Nov;124(Pt B):111017
International immunopharmacology 2023 Nov;124(Pt B):111017
Butyrate alleviates renal fibrosis in CKD by regulating NLRP3-mediated pyroptosis via the STING/NF-κB/p65 pathway.
Tian X, Zeng Y, Tu Q, Jiao Y, Yao S, Chen Y, Sun L, Xia Q, Luo Y, Yuan L, Jiang Q
International immunopharmacology 2023 Nov;124(Pt B):111010
International immunopharmacology 2023 Nov;124(Pt B):111010
Linderalactone mitigates diabetic cardiomyopathy in mice via suppressing the MAPK/ATF6 pathway.
Han X, Zhou W, Zhang J, Tu Y, Wei J, Zheng R, Zhu J, Xu D, Ying H, Wu G, Shi Q, Liang G
International immunopharmacology 2023 Nov;124(Pt B):110984
International immunopharmacology 2023 Nov;124(Pt B):110984
4-Octyl itaconate inhibits inflammation to attenuate psoriasis as an agonist of oxeiptosis.
You M, Jiang Q, Huang H, Ma F, Zhou X
International immunopharmacology 2023 Nov;124(Pt B):110915
International immunopharmacology 2023 Nov;124(Pt B):110915
Nuciferine protects against lipopolysaccharide-induced endometritis via inhibiting ferroptosis and modulating AMPKα/mTOR/HIF-1α signaling axis.
Jiang P, Zhao L, Hu R, Zhai Z, Guo J, Zhang K
International immunopharmacology 2023 Nov;124(Pt B):110914
International immunopharmacology 2023 Nov;124(Pt B):110914
Attenuated Salmonella-delivered PD-1 siRNA enhances the antitumor effects of EZH2 inhibitors in colorectal cancer.
Lv M, Guo S, Zhang X, Zou Y, Chen Q, Zang C, Huang S, Hu Y, Wang Y, Wang Q, Zhong J
International immunopharmacology 2023 Nov;124(Pt A):110918
International immunopharmacology 2023 Nov;124(Pt A):110918
Ferritin was involved in interleukin-17A enhanced osteogenesis through autophagy activation.
Yuan W, Yang Y, Wei Y, Yu X, Bao J, Zhong J, Wang Z, Chen L
International immunopharmacology 2023 Nov;124(Pt A):110916
International immunopharmacology 2023 Nov;124(Pt A):110916
The role of blood podoplanin in patients with viral myocarditis.
Liu C, Zhu M, Yang H, Tang Y, Nisa K, Lu Y, Yang H, Yuan J
International immunopharmacology 2023 Nov;124(Pt A):110889
International immunopharmacology 2023 Nov;124(Pt A):110889
3, 4-Benzopyrene (Bap) aggravated abdominal aortic aneurysm formation by targeting pyroptosis in smooth muscle cells through ET-1 mediated NLRP3-inflammasome activation.
Liu S, Xue YJ, Yin RP, Wu BS, Yu YW, Zhou YY, Wang J, Ji KT
International immunopharmacology 2023 Nov;124(Pt A):110851
International immunopharmacology 2023 Nov;124(Pt A):110851
Icaritin inhibits endometrial carcinoma cells by suppressing O-GlcNAcylation of FOXC1.
Wang Y, Wang G, Liu Y, Yang F, Zhang H, Kong Y
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Nov;120:155062
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Nov;120:155062
Sanguisorba officinalis ethyl acetate extract attenuates ulcerative colitis through inhibiting PI3K-AKT/NF-κB/ STAT3 pathway uncovered by single-cell RNA sequencing.
Li C, Gong L, Jiang Y, Huo X, Huang L, Lei H, Gu Y, Wang D, Guo D, Deng Y
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Nov;120:155052
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Nov;120:155052
A large-scale transcriptional analysis reveals herb-derived ginsenoside F2 suppressing hepatocellular carcinoma via inhibiting STAT3.
Tan X, Ma X, Dai Y, An J, Yu X, Li S, Liao Y, Pei T, Tang Y, Gui Y, Zhou S, Guo D, Deng Y, Hu K, Wang D
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Nov;120:155031
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Nov;120:155031
Comprehensive analysis of cuproptosis genes and cuproptosis-related genes as prognosis factors in esophageal squamous cell carcinoma.
Wu Z, Huang Z, Zhou X, Gao C, Peng Z, Zheng X, Zhang Y, Du Z, Wu B
Genomics 2023 Nov;115(6):110732
Genomics 2023 Nov;115(6):110732
Combination of PARP inhibitor and CDK4/6 inhibitor modulates cGAS/STING-dependent therapy-induced senescence and provides "one-two punch" opportunity with anti-PD-L1 therapy in colorectal cancer.
Wang T, Liu W, Shen Q, Tao R, Li C, Shen Q, Lin Y, Huang Y, Yang L, Xie G, Bai J, Li R, Wang L, Tao K, Yin Y
Cancer science 2023 Nov;114(11):4184-4201
Cancer science 2023 Nov;114(11):4184-4201
Oxytocin alleviates cognitive and memory impairments by decreasing hippocampal microglial activation and synaptic defects via OXTR/ERK/STAT3 pathway in a mouse model of sepsis-associated encephalopathy.
Jiang J, Zou Y, Xie C, Yang M, Tong Q, Yuan M, Pei X, Deng S, Tian M, Xiao L, Gong Y
Brain, behavior, and immunity 2023 Nov;114:195-213
Brain, behavior, and immunity 2023 Nov;114:195-213
Elastic modulus of hydrogel regulates osteogenic differentiation via liquid-liquid phase separation of YAP.
Tan K, Yang Q, Han Y, Zhuang Z, Zhao Y, Guo K, Tan A, Zheng Y, Li W
Journal of biomedical materials research. Part A 2023 Nov;111(11):1781-1797
Journal of biomedical materials research. Part A 2023 Nov;111(11):1781-1797
Musashi-2 binds with Fbxo6 to induce Rnaset2 ubiquitination and chemokine signaling pathway during vascular smooth muscle cell phenotypic switch in atherosclerosis.
Zhang T, Wu S, Xu R, Zhang S, Wang M, Li J
Cellular signalling 2023 Nov;111:110869
Cellular signalling 2023 Nov;111:110869
ADAMTS12 promotes oxaliplatin chemoresistance and angiogenesis in gastric cancer through VEGF upregulation.
Jiang Y, Huang J, Huang Z, Li W, Tan R, Li T, Chen Z, Tang X, Zhao Y, Qiu J, Li C, Chen H, Yang Z
Cellular signalling 2023 Nov;111:110866
Cellular signalling 2023 Nov;111:110866
CircTNPO1 promotes the tumorigenesis of osteosarcoma by sequestering miR-578 to upregulate WNT5A expression.
Shi Y, Tian Y, Wu Y, Zhao Y
Cellular signalling 2023 Nov;111:110858
Cellular signalling 2023 Nov;111:110858
β-hydroxybutyrate impairs the directionality of migrating neutrophils through inhibiting the autophagy-dependent degradation of Cdc42 and Rac1 in ketotic cows.
Yang Y, Jiang S, Yang J, Feng X, Wang C, Wang K, Gao W, Du X, Lei L, Wang Z, Liu G, Song Y, Li X
Journal of dairy science 2023 Nov;106(11):8005-8016
Journal of dairy science 2023 Nov;106(11):8005-8016
Elucidation of the mechanisms and molecular targets of KeChuanLiuWei-Mixture for treatment of severe asthma based on network pharmacology.
Cheng Y, Sun D, Zou L, Li S, Tang L, Yu X, Tang B, Wu Y, Fang H
Chemical biology & drug design 2023 Nov;102(5):1034-1049
Chemical biology & drug design 2023 Nov;102(5):1034-1049
The mixture of Radix isatidis, Forsythiae, and Gypsum alleviates lipopolysaccharide-induced fever in broilers by inhibition of TLR4/NF-κB signaling pathway.
Wang H, Zheng X, Lin Y, Zheng X, Yan M, Li Y, Shi D, Guo S, Liu C
Poultry science 2023 Nov;102(11):103032
Poultry science 2023 Nov;102(11):103032
DNA damage-mediated cellular senescence promotes hand-foot syndrome that can be relieved by thymidine prodrug.
Yang B, Xie X, Wu Z, Lv D, Hu J, Chen Y, Li J, Luo S, Li J, Luo J, Zhang S
Genes & diseases 2023 Nov;10(6):2557-2571
Genes & diseases 2023 Nov;10(6):2557-2571
Targeting USP8 Inhibits O-GlcNAcylation of SLC7A11 to Promote Ferroptosis of Hepatocellular Carcinoma via Stabilization of OGT.
Tang J, Long G, Hu K, Xiao D, Liu S, Xiao L, Zhou L, Tao Y
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Nov;10(33):e2302953
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Nov;10(33):e2302953
A HER2-targeted Antibody-Drug Conjugate, RC48-ADC, Exerted Promising Antitumor Efficacy and Safety with Intravesical Instillation in Preclinical Models of Bladder Cancer.
Hong X, Chen X, Wang H, Xu Q, Xiao K, Zhang Y, Chi Z, Liu Y, Liu G, Li H, Fang J, Lin T, Zhang Y
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Nov;10(32):e2302377
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Nov;10(32):e2302377
KLF5 Promotes Tumor Progression and Parp Inhibitor Resistance in Ovarian Cancer.
Wu Y, Chen S, Shao Y, Su Y, Li Q, Wu J, Zhu J, Wen H, Huang Y, Zheng Z, Chen X, Ju X, Huang S, Wu X, Hu Z
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Nov;10(31):e2304638
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Nov;10(31):e2304638
Withdrawal.
Photochemistry and photobiology 2023 Nov-Dec;99(6):1501
Blue Light Inhibits Proliferation of Metastatic Cancer Cells by Regulating Translational Initiation: A Synergistic Property with Anticancer Drugs.
Oh PS, Kim EM, Boud F, Lim S, Jeong HJ
Photochemistry and photobiology 2023 Nov-Dec;99(6):1438-1447
Photochemistry and photobiology 2023 Nov-Dec;99(6):1438-1447
Flavinated SDHA underlies the change in intrinsic optical properties of oral cancers.
Marumo T, Maduka CV, Ural E, Apu EH, Chung SJ, Tanabe K, van den Berg NS, Zhou Q, Martin BA, Miura T, Rosenthal EL, Shibahara T, Contag CH
Communications biology 2023 Nov 9;6(1):1134
Communications biology 2023 Nov 9;6(1):1134
Cryo-electron tomography of NLRP3-activated ASC complexes reveals organelle co-localization.
Liu Y, Zhai H, Alemayehu H, Boulanger J, Hopkins LJ, Borgeaud AC, Heroven C, Howe JD, Leigh KE, Bryant CE, Modis Y
Nature communications 2023 Nov 9;14(1):7246
Nature communications 2023 Nov 9;14(1):7246
Microglial voltage-dependent anion channel 1 signaling modulates sleep deprivation-induced transition to chronic postsurgical pain.
Wei SN, Zhang H, Lu Y, Yu HJ, Ma T, Wang SN, Yang K, Tian ML, Huang AH, Wang W, Li FS, Li YW
Sleep 2023 Nov 8;46(11)
Sleep 2023 Nov 8;46(11)
A conserved mechanism for JNK-mediated loss of Notch function in advanced prostate cancer.
Wang CW, Clémot M, Hashimoto T, Diaz JA, Goins LM, Goldstein AS, Nagaraj R, Banerjee U
Science signaling 2023 Nov 7;16(810):eabo5213
Science signaling 2023 Nov 7;16(810):eabo5213
Uncoupling Protein 3 Promotes the Myogenic Differentiation of Type IIb Myotubes in C2C12 Cells.
You Z, Wang J, Li F, Hei W, Li M, Guo X, Gao P, Cao G, Cai C, Li B
Genes 2023 Nov 7;14(11)
Genes 2023 Nov 7;14(11)
Covalent 14-3-3 Molecular Glues and Heterobifunctional Molecules Against Nuclear Transcription Factors and Regulators.
Shao Q, Duong TN, Park I, Nomura DK
bioRxiv : the preprint server for biology 2023 Nov 6;
bioRxiv : the preprint server for biology 2023 Nov 6;
Novel acridine-based LSD1 inhibitors enhance immune response in gastric cancer.
Dai XJ, Liu Y, Wang N, Chen HX, Wu JW, Xiong XP, Ji SK, Zhou Y, Shen L, Wang SP, Liu HM, Liu HM, Zheng YC
European journal of medicinal chemistry 2023 Nov 5;259:115684
European journal of medicinal chemistry 2023 Nov 5;259:115684
PGAM5 degrades PDCoV N protein and activates type I interferon to antagonize viral replication.
Yang X, Kong N, Qin W, Zhai X, Song Y, Tong W, Li L, Liu C, Zheng H, Yu H, Zhang W, Tong G, Shan T
Journal of virology 2023 Nov 30;97(11):e0147023
Journal of virology 2023 Nov 30;97(11):e0147023
Adhesion G Protein-Coupled Receptor G2 Promotes Hepatocellular Carcinoma Progression and Serves as a Neutrophil-Related Prognostic Biomarker.
Wu Q, Wang P, Peng Q, Kang Z, Deng Y, Li J, Chen Y, Li J, Ge F
International journal of molecular sciences 2023 Nov 30;24(23)
International journal of molecular sciences 2023 Nov 30;24(23)
PBRM1 mutation and WDR72 expression as potential combinatorial biomarker for predicting the response to Nivolumab in patients with ccRCC: a tumor marker prognostic study.
Chang Q, Sun J, Zhao S, Li L, Zhang N, Yan L, Fan Y, Liu J
Aging 2023 Nov 30;15(23):13753-13775
Aging 2023 Nov 30;15(23):13753-13775
PFKP confers chemoresistance by upregulating ABCC2 transporter in non-small cell lung cancer.
Wang Z, Wu S, Chen X, Liang J, Xue F, Cho WC, Bao J, Chen B, Ye M, Ma D, Zhu C, Zhu J, Shen J
Translational lung cancer research 2023 Nov 30;12(11):2294-2309
Translational lung cancer research 2023 Nov 30;12(11):2294-2309
The yeast prion protein Sup35 initiates α-synuclein pathology in mouse models of Parkinson's disease.
Meng L, Liu C, Li Y, Chen G, Xiong M, Yu T, Pan L, Zhang X, Zhou L, Guo T, Yuan X, Liu C, Zhang Z, Zhang Z
Science advances 2023 Nov 3;9(44):eadj1092
Science advances 2023 Nov 3;9(44):eadj1092
Selective activator of human ClpP triggers cell cycle arrest to inhibit lung squamous cell carcinoma.
Zhou LL, Zhang T, Xue Y, Yue C, Pan Y, Wang P, Yang T, Li M, Zhou H, Ding K, Gan J, Ji H, Yang CG
Nature communications 2023 Nov 3;14(1):7069
Nature communications 2023 Nov 3;14(1):7069
Extracellular vesicle-derived silk fibroin nanoparticles loaded with MFGE8 accelerate skin ulcer healing by targeting the vascular endothelial cells.
Luo L, Zhang H, Zhang S, Luo C, Kan X, Lv J, Zhao P, Tian Z, Li C
Journal of nanobiotechnology 2023 Nov 29;21(1):455
Journal of nanobiotechnology 2023 Nov 29;21(1):455
INPP5D regulates inflammasome activation in human microglia.
Chou V, Pearse RV 2nd, Aylward AJ, Ashour N, Taga M, Terzioglu G, Fujita M, Fancher SB, Sigalov A, Benoit CR, Lee H, Lam M, Seyfried NT, Bennett DA, De Jager PL, Menon V, Young-Pearse TL
Nature communications 2023 Nov 29;14(1):7552
Nature communications 2023 Nov 29;14(1):7552
Photothermal-Ionic-Pharmacotherapy of Myocardial Infarction with Enhanced Angiogenesis and Antiapoptosis.
Feng K, Ruan Y, Zhang X, Wu X, Liu Z, Sun X
ACS applied materials & interfaces 2023 Nov 29;
ACS applied materials & interfaces 2023 Nov 29;
METTL9-SLC7A11 axis promotes hepatocellular carcinoma progression through ferroptosis inhibition.
Bi F, Qiu Y, Wu Z, Liu S, Zuo D, Huang Z, Li B, Yuan Y, Niu Y, Qiu J
Cell death discovery 2023 Nov 28;9(1):428
Cell death discovery 2023 Nov 28;9(1):428
SETD4 inhibits prostate cancer development by promoting H3K27me3-mediated NUPR1 transcriptional repression and cell cycle arrest.
Wang C, Wang T, Li KJ, Hu LH, Li Y, Yu YZ, Xie T, Zhu S, Fu DJ, Wang Y, Zeng XZ, Liu FP, Chen H, Chen ZS, Feng NH, Liu J, Jiang Y, Zhao SC
Cancer letters 2023 Nov 28;579:216464
Cancer letters 2023 Nov 28;579:216464
The deubiquitinating enzyme USP19 facilitates hepatocellular carcinoma progression through stabilizing YAP.
Tian Z, Xu C, He W, Lin Z, Zhang W, Tao K, Ding R, Zhang X, Dou K
Cancer letters 2023 Nov 28;577:216439
Cancer letters 2023 Nov 28;577:216439
A bacteria-derived tetramerized protein ameliorates nonalcoholic steatohepatitis in mice via binding and relocating acetyl-coA carboxylase.
Lin Y, Yang M, Huang L, Yang F, Fan J, Qiang Y, Chang Y, Zhou W, Yan L, Xiong J, Ping J, Chen S, Men D, Li F
Cell reports 2023 Nov 28;42(11):113453
Cell reports 2023 Nov 28;42(11):113453
p53-responsive CMBL reprograms glucose metabolism and suppresses cancer development by destabilizing phosphofructokinase PFKP.
Huang Y, Xiong C, Wang C, Deng J, Zuo Z, Wu H, Xiong J, Wu X, Lu H, Hao Q, Zhou X
Cell reports 2023 Nov 28;42(11):113426
Cell reports 2023 Nov 28;42(11):113426
Inhibiting G6PD by quercetin promotes degradation of EGFR T790M mutation.
Ge Z, Xu M, Ge Y, Huang G, Chen D, Ye X, Xiao Y, Zhu H, Yin R, Shen H, Ma G, Qi L, Wei G, Li D, Wei S, Zhu M, Ma H, Shi Z, Wang X, Ge X, Qian X
Cell reports 2023 Nov 28;42(11):113417
Cell reports 2023 Nov 28;42(11):113417
Single-cell transcriptomics identifies a WNT7A-FZD5 signaling axis that maintains fallopian tube stem cells in patient-derived organoids.
Alsaadi A, Artibani M, Hu Z, Wietek N, Morotti M, Gonzalez LS, Alazzam M, Jiang J, Abdul B, Soleymani Majd H, Blazer LL, Adams J, Silvestri F, Sidhu SS, Brugge JS, Ahmed AA
Cell reports 2023 Nov 28;42(11):113354
Cell reports 2023 Nov 28;42(11):113354
PD-L1-mediated immune evasion in triple-negative breast cancer is linked to the loss of ZNF652.
Liu Y, Peng Y, Du W, Yu C, Peng Z, Qin L, Ma Y, Wu X, Peng Y, Cheng X, Xia L, Fa H, Wu Y, Sun L, Liu J, Liu Z, Shang Y, Wang S, Liang J
Cell reports 2023 Nov 28;42(11):113343
Cell reports 2023 Nov 28;42(11):113343
The yeast protein Ure2p triggers Tau pathology in a mouse model of tauopathy.
Meng L, Liu C, Liu M, Chen J, Liu C, Zhang Z, Chen G, Zhang Z
Cell reports 2023 Nov 28;42(11):113342
Cell reports 2023 Nov 28;42(11):113342
Neuro-Inspired Biomimetic Microreactor for Sensory Recovery and Hair Follicle Neogenesis under Skin Burns.
Zhao Q, Wang J, Qu S, Gong Z, Duan Y, Han L, Wang J, Wang C, Tan J, Yuan Q, Zhang Y
ACS nano 2023 Nov 28;17(22):23115-23131
ACS nano 2023 Nov 28;17(22):23115-23131
The Role of ZNF275/AKT Pathway in Carcinogenesis and Cisplatin Chemosensitivity of Cervical Cancer Using Patient-Derived Xenograft Models.
Ye M, Liu T, Miao L, Zou S, Ji H, Zhang J, Zhu X
Cancers 2023 Nov 28;15(23)
Cancers 2023 Nov 28;15(23)
Fucoidan Ameliorates Ferroptosis in Ischemia-reperfusion-induced Liver Injury through Nrf2/HO-1/GPX4 Activation.
Li JJ, Dai WQ, Mo WH, Xu WQ, Li YY, Guo CY, Xu XF
Journal of clinical and translational hepatology 2023 Nov 28;11(6):1341-1354
Journal of clinical and translational hepatology 2023 Nov 28;11(6):1341-1354
LSM14B is essential for oocyte meiotic maturation by regulating maternal mRNA storage and clearance.
Wan Y, Yang S, Li T, Cai Y, Wu X, Zhang M, Muhammad T, Huang T, Lv Y, Chan WY, Lu G, Li J, Sha QQ, Chen ZJ, Liu H
Nucleic acids research 2023 Nov 27;51(21):11652-11667
Nucleic acids research 2023 Nov 27;51(21):11652-11667
Hsa_circ_0009092/miR-665/NLK signaling axis suppresses colorectal cancer progression via recruiting TAMs in the tumor microenvironment.
Song J, Liu Q, Han L, Song T, Huang S, Zhang X, He Q, Liang C, Zhu S, Xiong B
Journal of experimental & clinical cancer research : CR 2023 Nov 27;42(1):319
Journal of experimental & clinical cancer research : CR 2023 Nov 27;42(1):319
LINC02086 promotes cell viability and inhibits cell apoptosis in breast cancer by sponging miR-6757-5p and up-regulating EPHA2.
Han X, Shi F, Guo S, Li Y, Wang H, Song C, Wu S
World journal of surgical oncology 2023 Nov 27;21(1):371
World journal of surgical oncology 2023 Nov 27;21(1):371
OTUD1 ameliorates cerebral ischemic injury through inhibiting inflammation by disrupting K63-linked deubiquitination of RIP2.
Zheng S, Li Y, Song X, Wu M, Yu L, Huang G, Liu T, Zhang L, Shang M, Zhu Q, Gao C, Chen L, Liu H
Journal of neuroinflammation 2023 Nov 27;20(1):281
Journal of neuroinflammation 2023 Nov 27;20(1):281
Lnc-PTCHD4-AS inhibits gastric cancer through MSH2-MSH6 dimerization and ATM-p53-p21 activation.
Wang J, Mi Y, Sun X, Xue X, Zhao H, Zhang M, Hu B, Bukhari I, Zheng P
Aging 2023 Nov 27;15(22):13558-13578
Aging 2023 Nov 27;15(22):13558-13578
Mitoguardin 1 and 2 promote granulosa cell proliferation by activating AKT and regulating the Hippo-YAP1 signaling pathway.
Yan MQ, Zhu BH, Liu XH, Yang YM, Duan XY, Wang Y, Sun H, Feng M, Li T, Liu XM
Cell death & disease 2023 Nov 27;14(11):779
Cell death & disease 2023 Nov 27;14(11):779
Knockdown of TACC3 inhibits tumor cell proliferation and increases chemosensitivity in pancreatic cancer.
Shi S, Guo D, Ye L, Li T, Fei Q, Lin M, Yu X, Jin K, Wu W
Cell death & disease 2023 Nov 27;14(11):778
Cell death & disease 2023 Nov 27;14(11):778
Long noncoding RNA NONHSAT160169.1 promotes resistance via hsa-let-7c-3p/SOX2 axis in gastric cancer.
Zhao X, Xu Z, Meng B, Ren T, Wang X, Hou R, Li S, Ma W, Liu D, Zheng J, Shi M
Scientific reports 2023 Nov 27;13(1):20858
Scientific reports 2023 Nov 27;13(1):20858
RMI1 facilitates repair of ionizing radiation-induced DNA damage and maintenance of genomic stability.
Fang L, Sun Y, Dong M, Yang M, Hao J, Li J, Zhang H, He N, Du L, Xu C
Cell death discovery 2023 Nov 25;9(1):426
Cell death discovery 2023 Nov 25;9(1):426
IFN-γ in ovarian tumor microenvironment upregulates HLA-E expression and predicts a poor prognosis.
Zheng H, Guan X, Meng X, Tong Y, Wang Y, Xie S, Guo L, Lu R
Journal of ovarian research 2023 Nov 25;16(1):229
Journal of ovarian research 2023 Nov 25;16(1):229
The Interaction between SARS-CoV-2 Nucleocapsid Protein and UBC9 Inhibits MAVS Ubiquitination by Enhancing Its SUMOylation.
Huang C, Yin Y, Pan P, Huang Y, Chen S, Chen J, Wang J, Xu G, Tao X, Xiao X, Li J, Yang J, Jin Z, Li B, Tong Z, Du W, Liu L, Liu Z
Viruses 2023 Nov 24;15(12)
Viruses 2023 Nov 24;15(12)
SOX18 Promotes the Proliferation of Dermal Papilla Cells via the Wnt/β-Catenin Signaling Pathway.
He M, Lv X, Cao X, Yuan Z, Getachew T, Li Y, Wang S, Sun W
International journal of molecular sciences 2023 Nov 23;24(23)
International journal of molecular sciences 2023 Nov 23;24(23)
Remdesivir Derivative VV116 Is a Potential Broad-Spectrum Inhibitor of Both Human and Animal Coronaviruses.
Liu W, Zhang M, Hu C, Song H, Mei Y, Liu Y, Zhang Q
Viruses 2023 Nov 23;15(12)
Viruses 2023 Nov 23;15(12)
BioE3 identifies specific substrates of ubiquitin E3 ligases.
Barroso-Gomila O, Merino-Cacho L, Muratore V, Perez C, Taibi V, Maspero E, Azkargorta M, Iloro I, Trulsson F, Vertegaal ACO, Mayor U, Elortza F, Polo S, Barrio R, Sutherland JD
Nature communications 2023 Nov 23;14(1):7656
Nature communications 2023 Nov 23;14(1):7656
Mid-old cells are a potential target for anti-aging interventions in the elderly.
Kim YH, Lee YK, Park SS, Park SH, Eom SY, Lee YS, Lee WJ, Jang J, Seo D, Kang HY, Kim JC, Lim SB, Yoon G, Kim HS, Kim JH, Park TJ
Nature communications 2023 Nov 22;14(1):7619
Nature communications 2023 Nov 22;14(1):7619
ALS/FTD-associated mutation in cyclin F inhibits ER-Golgi trafficking, inducing ER stress, ERAD and Golgi fragmentation.
Ragagnin AMG, Sundaramoorthy V, Farzana F, Gautam S, Saravanabavan S, Takalloo Z, Mehta P, Do-Ha D, Parakh S, Shadfar S, Hunter J, Vidal M, Jagaraj CJ, Brocardo M, Konopka A, Yang S, Rayner SL, Williams KL, Blair IP, Chung RS, Lee A, Ooi L, Atkin JD
Scientific reports 2023 Nov 22;13(1):20467
Scientific reports 2023 Nov 22;13(1):20467
Heteromeric formation with βA3 protects the low thermal stability of βB1-L116P.
Xu J, Zhang Y, Liu J, Hu L, Luo C, Yao K, Chen X
The British journal of ophthalmology 2023 Nov 22;107(12):1936-1942
The British journal of ophthalmology 2023 Nov 22;107(12):1936-1942
Ascomylactam C Induces an Immunogenic Cell Death Signature via Mitochondria-Associated ER Stress in Lung Cancer and Melanoma.
Huang Y, Yan H, Zhang B, Zhu G, Yu J, Xiao X, He W, Chen Y, Gao X, She Z, Li M, Yuan J
Marine drugs 2023 Nov 21;21(12)
Marine drugs 2023 Nov 21;21(12)
Hepatocyte integrity depends on c-Jun-controlled proliferation in Schistosoma mansoni infected mice.
Härle L, von Bülow V, Knedla L, Stettler F, Müller H, Zahner D, Haeberlein S, Windhorst A, Tschuschner A, Burg-Roderfeld M, Köhler K, Grevelding CG, Roeb E, Roderfeld M
Scientific reports 2023 Nov 21;13(1):20390
Scientific reports 2023 Nov 21;13(1):20390
MiniBAR/GARRE1 is a dual Rac and Rab effector required for ciliogenesis.
Serres MP, Shaughnessy R, Escot S, Hammich H, Cuvelier F, Salles A, Rocancourt M, Verdon Q, Gaffuri AL, Sourigues Y, Malherbe G, Velikovsky L, Chardon F, Sassoon N, Tinevez JY, Callebaut I, Formstecher E, Houdusse A, David NB, Pylypenko O, Echard A
Developmental cell 2023 Nov 20;58(22):2477-2494.e8
Developmental cell 2023 Nov 20;58(22):2477-2494.e8
LMP2 and TAP2 impair tumor growth and metastasis by inhibiting Wnt/β-catenin signaling pathway and EMT in cervical cancer.
Cheng Z, Wang H, Yang Z, Li J, Chen X
BMC cancer 2023 Nov 20;23(1):1128
BMC cancer 2023 Nov 20;23(1):1128
Inhibiting Rev-erbα-mediated ferroptosis alleviates susceptibility to myocardial ischemia-reperfusion injury in type 2 diabetes.
Huang Q, Tian H, Tian L, Zhao X, Li L, Zhang Y, Qiu Z, Lei S, Xia Z
Free radical biology & medicine 2023 Nov 20;209(Pt 1):135-150
Free radical biology & medicine 2023 Nov 20;209(Pt 1):135-150
BCAS2 Participates in Insulin Synthesis and Secretion via mRNA Alternative Splicing in Mice.
Chen X, Xie X, Li J, Sun L, Lv Z, Yao X, Li L, Jin H, Cui S, Liu J
Endocrinology 2023 Nov 20;165(1)
Endocrinology 2023 Nov 20;165(1)
Vitamin D Attenuates Ulcerative Colitis by Inhibiting ACSL4-Mediated Ferroptosis.
Gao S, Sun C, Kong J
Nutrients 2023 Nov 20;15(22)
Nutrients 2023 Nov 20;15(22)
PHB2 Alleviates Neurotoxicity of Prion Peptide PrP(106-126) via PINK1/Parkin-Dependent Mitophagy.
Zheng X, Liu K, Xie Q, Xin H, Chen W, Lin S, Feng D, Zhu T
International journal of molecular sciences 2023 Nov 2;24(21)
International journal of molecular sciences 2023 Nov 2;24(21)
Covalent Degrader of the Oncogenic Transcription Factor β-Catenin.
Gowans FA, Forte N, Hatcher J, Huang OW, Wang Y, Poblano BEA, Wertz IE, Nomura DK
bioRxiv : the preprint server for biology 2023 Nov 2;
bioRxiv : the preprint server for biology 2023 Nov 2;
Exploiting the Cullin E3 Ligase Adaptor Protein SKP1 for Targeted Protein Degradation.
Hong SH, Osa A, Huang OW, Wertz IE, Nomura DK
bioRxiv : the preprint server for biology 2023 Nov 2;
bioRxiv : the preprint server for biology 2023 Nov 2;
Cinnamaldehyde Alleviates Bone Loss by Targeting Oxidative Stress and Mitochondrial Damage via the Nrf2/HO-1 Pathway in BMSCs and Ovariectomized Mice.
Lin BH, Ma RX, Wu JT, Du SQ, Lv YY, Yu HN, Zhang W, Mao SM, Liu GY, Bu YT, Chen ZH, Jin C, Wu ZY, Yang L
Journal of agricultural and food chemistry 2023 Nov 2;
Journal of agricultural and food chemistry 2023 Nov 2;
Resensitizing Paclitaxel-Resistant Ovarian Cancer via Targeting Lipid Metabolism Key Enzymes CPT1A, SCD and FASN.
Ma Q, Liu Z, Wang T, Zhao P, Liu M, Wang Y, Zhao W, Yuan Y, Li S
International journal of molecular sciences 2023 Nov 19;24(22)
International journal of molecular sciences 2023 Nov 19;24(22)
Agathis dammara Extract and its Monomer Araucarone Attenuate Abdominal Aortic Aneurysm in Mice.
Zhang Q, Cai Z, Yu Z, Di C, Qiu Y, Qi R
Cardiovascular drugs and therapy 2023 Nov 18;
Cardiovascular drugs and therapy 2023 Nov 18;
MiR-337-3p improves metabolic-associated fatty liver disease through regulation of glycolipid metabolism.
Xu X, Yu C, He H, Pan X, Hou A, Feng J, Tan R, Gong L, Chen J, Ren J
iScience 2023 Nov 17;26(11):108352
iScience 2023 Nov 17;26(11):108352
JUN mediates glucocorticoid resistance by stabilizing HIF1a in T cell acute lymphoblastic leukemia.
Zhang Z, Shi J, Wu Q, Zhang Z, Liu X, Ren A, Zhao G, Dong G, Wu H, Zhao J, Zhao Y, Hu J, Li H, Zhang T, Zhou F, Zhu H
iScience 2023 Nov 17;26(11):108242
iScience 2023 Nov 17;26(11):108242
Fibromodulin overexpression drives oral squamous cell carcinoma via activating downstream EGFR signaling.
Xia L, Zhang T, Yao J, Lu K, Hu Z, Gu X, Chen Y, Qin S, Leng W
iScience 2023 Nov 17;26(11):108201
iScience 2023 Nov 17;26(11):108201
FUS-dependent microRNA deregulations identify TRIB2 as a druggable target for ALS motor neurons.
Ho WY, Chak LL, Hor JH, Liu F, Diaz-Garcia S, Chang JC, Sanford E, Rodriguez MJ, Alagappan D, Lim SM, Cho YL, Shimizu Y, Sun AX, Tyan SH, Koo E, Kim SH, Ravits J, Ng SY, Okamura K, Ling SC
iScience 2023 Nov 17;26(11):108152
iScience 2023 Nov 17;26(11):108152
The splicing factor DHX38 enables retinal development through safeguarding genome integrity.
Sun K, Han Y, Li J, Yu S, Huang Y, Zhang Y, Reilly J, Tu J, Gao P, Jia D, Chen X, Hu H, Ren M, Li P, Luo J, Ren X, Zhang X, Shu X, Liu F, Liu M, Tang Z
iScience 2023 Nov 17;26(11):108103
iScience 2023 Nov 17;26(11):108103
CD9 exacerbates pathological cardiac hypertrophy through regulating GP130/STAT3 signaling pathway.
Li Y, Fan S, Kong L, Hao Z, Zhou Y, Shangguan J, Gao L, Wang M, Kang Y, Li X, Huang K, Zhang C, Liu Z
iScience 2023 Nov 17;26(11):108070
iScience 2023 Nov 17;26(11):108070
Photoperiod Induces the Epigenetic Change of the GNAQ Gene in OVX+E(2) Ewes.
Wang W, Du X, Chu M, He X
International journal of molecular sciences 2023 Nov 17;24(22)
International journal of molecular sciences 2023 Nov 17;24(22)
Blockage of CacyBP inhibits macrophage recruitment and improves anti-PD-1 therapy in hepatocellular carcinoma.
Wang J, Zhang X, Ma X, Chen D, Cai M, Xiao L, Li J, Huang Z, Huang Y, Lian Y
Journal of experimental & clinical cancer research : CR 2023 Nov 16;42(1):303
Journal of experimental & clinical cancer research : CR 2023 Nov 16;42(1):303
HDAC3 and HDAC8 PROTAC dual degrader reveals roles of histone acetylation in gene regulation.
Xiao Y, Hale S, Awasthee N, Meng C, Zhang X, Liu Y, Ding H, Huo Z, Lv D, Zhang W, He M, Zheng G, Liao D
Cell chemical biology 2023 Nov 16;30(11):1421-1435.e12
Cell chemical biology 2023 Nov 16;30(11):1421-1435.e12
The proteomics analysis of extracellular vesicles revealed the possible function of heat shock protein 60 in Helicobacter pylori infection.
Li Y, Cao H, Qiu D, Wang N, Wang Y, Wen T, Wang J, Zhu H
Cancer cell international 2023 Nov 16;23(1):272
Cancer cell international 2023 Nov 16;23(1):272
Tripartite motif 31 drives gastric cancer cell proliferation and invasion through activating the Wnt/β-catenin pathway by regulating Axin1 protein stability.
Feng Q, Nie F, Gan L, Wei X, Liu P, Liu H, Zhang K, Fang Z, Wang H, Fang N
Scientific reports 2023 Nov 16;13(1):20099
Scientific reports 2023 Nov 16;13(1):20099
Structural determinants specific for retromer protein sorting nexin 5 in regulating subcellular retrograde membrane trafficking.
Chen Q, Sun M, Han X, Xu H, Liu Y
Journal of biomedical research 2023 Nov 15;37(6):492-506
Journal of biomedical research 2023 Nov 15;37(6):492-506
Deciphering the anti-renal fibrosis mechanism of triptolide in diabetic nephropathy by the integrative approach of network pharmacology and experimental verification.
Fan D, Ying Z, Yang Y, Qian Q, Li Y, Wang P, An X, Yan M
Journal of ethnopharmacology 2023 Nov 15;316:116774
Journal of ethnopharmacology 2023 Nov 15;316:116774
Extracts of Oldenlandia diffusa protects chondrocytes via inhibiting apoptosis and associated inflammatory response in osteoarthritis.
Lou C, Lin C, Wang W, Jiang H, Cai T, Lin S, Xue X, Lin J, Pan X
Journal of ethnopharmacology 2023 Nov 15;316:116744
Journal of ethnopharmacology 2023 Nov 15;316:116744
The total alkaloids of Sophora alopecuroides L. improve depression-like behavior in mice via BDNF-mediated AKT/mTOR signaling pathway.
Li J, Zhang M, Pei Y, Yang Q, Zheng L, Wang G, Sun Y, Yang W, Liu L
Journal of ethnopharmacology 2023 Nov 15;316:116723
Journal of ethnopharmacology 2023 Nov 15;316:116723
Loss of TMEM106B exacerbates Tau pathology and neurodegeneration in PS19 mice.
Feng T, Du H, Hu F
bioRxiv : the preprint server for biology 2023 Nov 15;
bioRxiv : the preprint server for biology 2023 Nov 15;
Quantitatively Lighting up the Spatial Organization of CD47/SIRPα Immune Checkpoints on the Cellular Membrane with Single-Molecule Localization Microscopy.
Wei Y, Zhao M, He T, Chen N, Rao L, Chen L, Zhang Y, Yang Y, Yuan Q
ACS nano 2023 Nov 14;17(21):21626-21638
ACS nano 2023 Nov 14;17(21):21626-21638
Integrating Metabolomics and Network Pharmacology to Explore the Mechanism of Xiao-Yao-San in the Treatment of Inflammatory Response in CUMS Mice.
Zhang Y, Li XJ, Wang XR, Wang X, Li GH, Xue QY, Zhang MJ, Ao HQ
Pharmaceuticals (Basel, Switzerland) 2023 Nov 14;16(11)
Pharmaceuticals (Basel, Switzerland) 2023 Nov 14;16(11)
Progenitor-like exhausted SPRY1(+)CD8(+) T cells potentiate responsiveness to neoadjuvant PD-1 blockade in esophageal squamous cell carcinoma.
Liu Z, Zhang Y, Ma N, Yang Y, Ma Y, Wang F, Wang Y, Wei J, Chen H, Tartarone A, Velotta JB, Dayyani F, Gabriel E, Wakefield CJ, Kidane B, Carbonelli C, Long L, Liu Z, Su J, Li Z
Cancer cell 2023 Nov 13;41(11):1852-1870.e9
Cancer cell 2023 Nov 13;41(11):1852-1870.e9
Spatial proteo-transcriptomic profiling reveals the molecular landscape of borderline ovarian tumors and their invasive progression.
Schweizer L, Krishnan R, Shimizu A, Metousis A, Kenny H, Mendoza R, Nordmann TM, Rauch S, Kelliher L, Heide J, Rosenberger FA, Bilecz A, Borrego SN, Strauss MT, Thielert M, Rodriguez E, Müller-Reif JB, Chen M, Yamada SD, Mund A, Lastra RR, Mann M, Lengyel E
medRxiv : the preprint server for health sciences 2023 Nov 13;
medRxiv : the preprint server for health sciences 2023 Nov 13;
IDH1(R132H) mutation increases radiotherapy efficacy and a 4-gene radiotherapy-related signature of WHO grade 4 gliomas.
Han X, Zhou H, Sun W, Hou L, Wang Y, Wang H, Lv Z, Xue X
Scientific reports 2023 Nov 11;13(1):19659
Scientific reports 2023 Nov 11;13(1):19659
Mechanism underlying the effect of Pulsatilla decoction in hepatocellular carcinoma treatment: a network pharmacology and in vitro analysis.
Liu K, Cao Z, Huang S, Kong F
BMC complementary medicine and therapies 2023 Nov 10;23(1):405
BMC complementary medicine and therapies 2023 Nov 10;23(1):405
Accelerating Wound Closure With Metrnl in Normal and Diabetic Mouse Skin.
Song L, Chang X, Hu L, Liu L, Wang G, Huang Y, Xu L, Jin B, Song J, Hu L, Zhang T, Wang Y, Xiao Y, Zhang F, Shi M, Liu L, Chen Q, Guo B, Zhou Y
Diabetes 2023 Nov 1;72(11):1692-1706
Diabetes 2023 Nov 1;72(11):1692-1706
Cholesterol mediated ferroptosis suppression reveals essential roles of Coenzyme Q and squalene.
Sun Q, Liu D, Cui W, Cheng H, Huang L, Zhang R, Gu J, Liu S, Zhuang X, Lu Y, Chu B, Li J
Communications biology 2023 Nov 1;6(1):1108
Communications biology 2023 Nov 1;6(1):1108
Col3a1 delivered via extracellular vesicles of Sertoli cells is essential for mice Sertoli cell proliferation.
Zhu Y, Lin Y, Zheng X, Wang H, Li Z, Sun F
Molecular and cellular endocrinology 2023 Nov 1;577:112036
Molecular and cellular endocrinology 2023 Nov 1;577:112036
Salt-inducible kinases regulate androgen synthesis in theca cells by enhancing CREB signaling.
Rodriguez Esquivel M, Hayes E, Lakomy O, Hassan M, Foretz M, Stocco C
Molecular and cellular endocrinology 2023 Nov 1;577:112030
Molecular and cellular endocrinology 2023 Nov 1;577:112030
Resistance exercise alleviates dexamethasone-induced muscle atrophy via Sestrin2/MSTN pathway in C57BL/6J mice.
Yang Y, Yang X, Huang Y, Liu S, Niu Y, Fu L
Experimental cell research 2023 Nov 1;432(1):113779
Experimental cell research 2023 Nov 1;432(1):113779
MnO(2) nanoparticles and MnSO(4) differentially affected hepatic lipid metabolism through miR-92a/acsl3-dependent de novo lipogenesis in yellow catfish Pelteobagrusfulvidraco.
Zhao T, Zheng H, Xu JJ, Xu YC, Liu LL, Luo Z
Environmental pollution (Barking, Essex : 1987) 2023 Nov 1;336:122416
Environmental pollution (Barking, Essex : 1987) 2023 Nov 1;336:122416
Integrated proteomics and phosphoproteomics analyses of esophageal cancer cells with different invasive abilities.
Xu N, Lai C, He QM, Cai Y, Yu H, Zhong W, Chen S, Wu FC, Chen H
Life sciences 2023 Nov 1;332:122078
Life sciences 2023 Nov 1;332:122078
Skeletal muscle-derived FSTL1 starting up angiogenesis by regulating endothelial junction via activating Src pathway can be upregulated by hydrogen sulfide.
Li MY, Gao RP, Zhu Q, Chen Y, Tao BB, Zhu YC
American journal of physiology. Cell physiology 2023 Nov 1;325(5):C1252-C1266
American journal of physiology. Cell physiology 2023 Nov 1;325(5):C1252-C1266
MARCH8 downregulation modulates profibrotic responses including myofibroblast differentiation.
Guo X, Adeyanju O, Olajuyin AM, Mandlem V, Sunil C, Adewumi J, Huang S, Tucker TA, Idell S, Qian G
American journal of physiology. Cell physiology 2023 Nov 1;325(5):C1190-C1200
American journal of physiology. Cell physiology 2023 Nov 1;325(5):C1190-C1200
Intrathecal delivery of AAV-NDNF ameliorates disease progression of ALS mice.
Cheng W, Huang J, Fu XQ, Tian WY, Zeng PM, Li Y, Luo ZG
Molecular therapy : the journal of the American Society of Gene Therapy 2023 Nov 1;31(11):3277-3289
Molecular therapy : the journal of the American Society of Gene Therapy 2023 Nov 1;31(11):3277-3289
Restricted tRNA methylation by intermolecular disulfide bonds in DNMT2/TRDMT1.
Li H, Zhu D, Yang Y, Ma Y, Chen Y, Xue P, Chen J, Qin M, Xu D, Cai C, Cheng H
International journal of biological macromolecules 2023 Nov 1;251:126310
International journal of biological macromolecules 2023 Nov 1;251:126310
Nrf2 depletion in the context of loss-of-function Keap1 leads to mitolysosome accumulation.
Dayalan Naidu S, Angelova PR, Knatko EV, Leonardi C, Novak M, de la Vega L, Ganley IG, Abramov AY, Dinkova-Kostova AT
Free radical biology & medicine 2023 Nov 1;208:478-493
Free radical biology & medicine 2023 Nov 1;208:478-493
STING promotes ferroptosis through NCOA4-dependent ferritinophagy in acute kidney injury.
Jin L, Yu B, Wang H, Shi L, Yang J, Wu L, Gao C, Pan H, Han F, Lin W, Lai EY, Wang YF, Yang Y
Free radical biology & medicine 2023 Nov 1;208:348-360
Free radical biology & medicine 2023 Nov 1;208:348-360
Exosomes derived from schwann cells alleviate mitochondrial dysfunction and necroptosis after spinal cord injury via AMPK signaling pathway-mediated mitophagy.
Xu B, Zhou Z, Fang J, Wang J, Tao K, Liu J, Liu S
Free radical biology & medicine 2023 Nov 1;208:319-333
Free radical biology & medicine 2023 Nov 1;208:319-333
High-fat diet induces C-reactive protein secretion, promoting lung adenocarcinoma via immune microenvironment modulation.
Hsu WL, Hsieh YT, Chen WM, Chien MH, Luo WJ, Chang JH, Devlin K, Su KY
Disease models & mechanisms 2023 Nov 1;16(11)
Disease models & mechanisms 2023 Nov 1;16(11)
Follicle-stimulating hormone orchestrates glucose-stimulated insulin secretion of pancreatic islets.
Cheng Y, Zhu H, Ren J, Wu HY, Yu JE, Jin LY, Pang HY, Pan HT, Luo SS, Yan J, Dong KX, Ye LY, Zhou CL, Pan JX, Meng ZX, Yu T, Jin L, Lin XH, Wu YT, Yang HB, Liu XM, Sheng JZ, Ding GL, Huang HF
Nature communications 2023 Nov 1;14(1):6991
Nature communications 2023 Nov 1;14(1):6991
Butyrate prevents the migration and invasion, and aerobic glycolysis in gastric cancer via inhibiting Wnt/β-catenin/c-Myc signaling.
Liang Y, Rao Z, Du D, Wang Y, Fang T
Drug development research 2023 May;84(3):532-541
Drug development research 2023 May;84(3):532-541
Synergistic ferroptosis-starvation therapy for bladder cancer based on hyaluronic acid modified metal-organic frameworks.
Wang Y, Xie K, Chen W, Fang Y, Mo Q, Zhang H, Zhao X, Li D, Tan W, Zhao P, Li F
Bioengineering & translational medicine 2023 May;8(3):e10515
Bioengineering & translational medicine 2023 May;8(3):e10515
Reactive oxygen species-responsive mitochondria-targeted liposomal quercetin attenuates retinal ischemia-reperfusion injury via regulating SIRT1/FOXO3A and p38 MAPK signaling pathways.
Zhao L, Ling L, Lu J, Jiang F, Sun J, Zhang Z, Huang Y, Liu X, Zhu Y, Fu X, Peng S, Yuan W, Zhao R, Zhang Z
Bioengineering & translational medicine 2023 May;8(3):e10460
Bioengineering & translational medicine 2023 May;8(3):e10460
Klotho improves cardiac fibrosis, inflammatory cytokines, ferroptosis, and oxidative stress in mice with myocardial infarction.
Wang K, Li Z, Ding Y, Liu Z, Li Y, Liu X, Sun Y, Hong J, Zheng W, Qian L, Xu D
Journal of physiology and biochemistry 2023 May;79(2):341-353
Journal of physiology and biochemistry 2023 May;79(2):341-353
Proline-rich 11 (PRR11) promotes the progression of cutaneous squamous cell carcinoma by activating the EGFR signaling pathway.
Wang S, Zhang X, Lei H, Song L, Huang Y, Kang T, Zhang M, Wang N, Yang P, Feng S, Wang J, Bai R, Wang N, Wang W, Zheng Y
Molecular carcinogenesis 2023 May;62(5):613-627
Molecular carcinogenesis 2023 May;62(5):613-627
Mast cells disrupt the duodenal mucosal integrity: Implications for the mechanisms of barrier dysfunction in functional dyspepsia.
Wang Z, Hao M, Wu L, He Y, Sun X
Scandinavian journal of gastroenterology 2023 May;58(5):460-470
Scandinavian journal of gastroenterology 2023 May;58(5):460-470
Scalable preparation of osteogenic micro-tissues derived from hESC-derived immunity-and-matrix-regulatory cells within porous microcarriers in suspension culture.
Ma H, Gao T, Wang L, Mohsin A, Hao J, Guo M, Wu J
Cell proliferation 2023 May;56(5):e13466
Cell proliferation 2023 May;56(5):e13466
Andrographolide exerts anti-respiratory syncytial virus activity by up-regulating heme oxygenase-1 independent of interferon responses in human airway epithelial cells.
Che S, Zhou N, Liu Y, Xie J, Liu E
Molecular biology reports 2023 May;50(5):4261-4272
Molecular biology reports 2023 May;50(5):4261-4272
TRIP13 overexpression promotes gefitinib resistance in non‑small cell lung cancer via regulating autophagy and phosphorylation of the EGFR signaling pathway.
Xiao Z, Li M, Zhang X, Rong X, Xu H
Oncology reports 2023 May;49(5)
Oncology reports 2023 May;49(5)
Targeting PI3Kα overcomes resistance to KRas(G12C) inhibitors mediated by activation of EGFR and/or IGF1R.
Qi WL, Li HY, Wang Y, Xu L, Deng JT, Zhang X, Wang YX, Meng LH
Acta pharmacologica Sinica 2023 May;44(5):1083-1094
Acta pharmacologica Sinica 2023 May;44(5):1083-1094
ZD6474 attenuates TGF-β1-induced fibrosis in human Tenon fibroblasts and inhibits neovascularization via AKT-mTOR signaling pathway.
Liu W, Chen Y, Song X, Xue Y, Zhang Y
International ophthalmology 2023 May;43(5):1523-1536
International ophthalmology 2023 May;43(5):1523-1536
LZTFL1 inhibits kidney tumor cell growth by destabilizing AKT through ZNRF1-mediated ubiquitin proteosome pathway.
Lu J, Fu LM, Cao Y, Fang Y, Cao JZ, Pan YH, Cen JJ, Liang YP, Chen ZH, Wei JH, Huang Y, Mumin MA, Xu QH, Wang YH, Zhu JQ, Liang H, Wang Z, Deng Q, Chen W, Jin XH, Liu ZP, Luo JH
Oncogene 2023 May;42(19):1543-1557
Oncogene 2023 May;42(19):1543-1557
Gli1 depletion induces oxidative stress and apoptosis of nucleus pulposus cells via Fos in intervertebral disc degeneration.
Liu L, Zhang Y, Fu J, Ai X, Long D, Leng X, Zhang Y, Huang B, Li C, Zhou Y, Feng C
Journal of orthopaedic translation 2023 May;40:116-131
Journal of orthopaedic translation 2023 May;40:116-131
The pan-cancer analysis of the oncogenic role of FAM72A as a BRCA prognostic biomarker and immunotherapeutic target.
Xu Y, Hirachan S, Shen Y, Huang Q, Bhandari A, Xia E
Environmental toxicology 2023 May;38(5):1100-1117
Environmental toxicology 2023 May;38(5):1100-1117
Circular RNA SLTM as a miR-421-competing endogenous RNA to mediate HMGB2 expression stimulates apoptosis and inflammation in arthritic chondrocytes.
Zhang H, Xiang X, Zhou B, Chen J, Sun Y, Zhang S, Li A, Li J
Journal of biochemical and molecular toxicology 2023 May;37(5):e23306
Journal of biochemical and molecular toxicology 2023 May;37(5):e23306
Analysis of CRSsNP Proteome Using a Highly Multiplexed Approach in Nasal Mucus.
Pesold VV, Wendler O, Morgenthaler L, Gröhn F, Mueller SK
American journal of rhinology & allergy 2023 May;37(3):348-359
American journal of rhinology & allergy 2023 May;37(3):348-359
Silencing of adipocyte enhancer-binding protein 1 (AEBP1) alleviates renal fibrosis in vivo and in vitro via inhibition of the β-catenin signaling pathway.
Liu N, Liu D, Cao S, Lei J
Human cell 2023 May;36(3):972-986
Human cell 2023 May;36(3):972-986
CircRNA_0017076 acts as a sponge for miR-185-5p in the control of epithelial-to-mesenchymal transition of tubular epithelial cells during renal interstitial fibrosis.
Zhang F, Zou H, Li X, Liu J, Xie Y, Chen M, Yu J, Wu X, Guo B
Human cell 2023 May;36(3):1024-1040
Human cell 2023 May;36(3):1024-1040
Rational design of a polysaccharide-based viral mimicry nanocomplex for potent gene silencing in inflammatory tissues.
Gao H, Wang S, Long Q, Cheng R, Lian W, Koivuniemi A, Ma M, Zhang B, Hirvonen J, Deng X, Liu Z, Ye X, Santos HA
Journal of controlled release : official journal of the Controlled Release Society 2023 May;357:120-132
Journal of controlled release : official journal of the Controlled Release Society 2023 May;357:120-132
The deubiquitinating enzyme UCHL3 promotes anaplastic thyroid cancer progression and metastasis through Hippo signaling pathway.
Tang J, Yang Q, Mao C, Xiao D, Liu S, Xiao L, Zhou L, Wu G, Tao Y
Cell death and differentiation 2023 May;30(5):1247-1259
Cell death and differentiation 2023 May;30(5):1247-1259
TRIM28 negatively regulates the RLR signaling pathway by targeting MAVS for degradation via K48-linked polyubiquitination.
Chen YY, Ran XH, Ni RZ, Mu D
The Journal of biological chemistry 2023 May;299(5):104660
The Journal of biological chemistry 2023 May;299(5):104660
The Wnt pathway protein Dvl1 targets somatostatin receptor 2 for lysosome-dependent degradation.
Carr HS, Zuo Y, Frost JA
The Journal of biological chemistry 2023 May;299(5):104645
The Journal of biological chemistry 2023 May;299(5):104645
Apicidin attenuates memory deficits by reducing the Aβ load in APP/PS1 mice.
Luo B, Chen J, Zhou GF, Xie XY, Tang J, Wen QX, Song L, Xie SQ, Long Y, Chen GJ, Hu XT
CNS neuroscience & therapeutics 2023 May;29(5):1300-1311
CNS neuroscience & therapeutics 2023 May;29(5):1300-1311
Transcriptomic and antiviral analyses of PoIFN-Delta5 against porcine enteric viruses in porcine intestinal epithelial cells.
Zhu X, Fan B, Song S, Gao J, Zhou J, Zhao Y, Guo W, Zhang X, Qian J, Zhu M, Li J, Li Y, Guo R, Fan H, Dong H, Zhang X, Li B
Veterinary microbiology 2023 May;280:109718
Veterinary microbiology 2023 May;280:109718
Deleting UL49.5 in duck plague virus causes attachment, entry and spread defects.
Li C, Wang M, Cheng A, Tian B, Huang J, Wu Y, Yang Q, Gao Q, Sun D, Zhang S, Ou X, Mao S, Zhao X, Jia R, Liu M, Chen S, Zhu D
Veterinary microbiology 2023 May;280:109707
Veterinary microbiology 2023 May;280:109707
Ambient particulate matter exposure plus chronic ethanol ingestion exacerbates hepatic fibrosis by triggering the mitochondrial ROS-ferroptosis signaling pathway in mice.
Ding S, Jiang J, Zhang G, Yu M, Zheng Y
Ecotoxicology and environmental safety 2023 May;256:114897
Ecotoxicology and environmental safety 2023 May;256:114897
Microcystin leucine arginine induces human sperm damage: Involvement of the Ca(2+)/CaMKKβ/AMPK pathway.
Guo X, Meng R, Liu J, Zhang S, Liu H, Du X, Zhang H, Li Y
Ecotoxicology and environmental safety 2023 May;256:114845
Ecotoxicology and environmental safety 2023 May;256:114845
Genome-wide CRISPR screens identify ILF3 as a mediator of mTORC1-dependent amino acid sensing.
Yan G, Yang J, Li W, Guo A, Guan J, Liu Y
Nature cell biology 2023 May;25(5):754-764
Nature cell biology 2023 May;25(5):754-764
Deciphering the Clinical Significance and Kinase Functions of GSK3α in Colon Cancer by Proteomics and Phosphoproteomics.
Gao L, Lu Y, Chen HN, Li Z, Hu M, Zhang R, Wang X, Xu Z, Gong Y, Wang R, Du D, Hai S, Li S, Su D, Li Y, Xu H, Zhou ZG, Dai L
Molecular & cellular proteomics : MCP 2023 May;22(5):100545
Molecular & cellular proteomics : MCP 2023 May;22(5):100545
Phenotypic Heterogeneity Analysis of APC-Mutant Colon Cancer by Proteomics and Phosphoproteomics Identifies RAI14 as a Key Prognostic Determinant in East Asians and Westerners.
Zhang R, Hu M, Chen HN, Wang X, Xia Z, Liu Y, Wang R, Xia X, Shu Y, Du D, Meng W, Qi S, Li Y, Xu H, Zhou ZG, Dai L
Molecular & cellular proteomics : MCP 2023 May;22(5):100532
Molecular & cellular proteomics : MCP 2023 May;22(5):100532
Characterization of GSDME in amphioxus provides insights into the functional evolution of GSDM-mediated pyroptosis.
Wang X, Wei X, Lu Y, Wang Q, Fu R, Wang Y, Wang Q, Wang X, Chen S, Xu A, Yuan S
PLoS biology 2023 May;21(5):e3002062
PLoS biology 2023 May;21(5):e3002062
Protein Kinase CK2 Promotes Proliferation, Abnormal Differentiation, and Proinflammatory Cytokine Production of Keratinocytes via Regulation of STAT3 and Akt Pathways in Psoriasis.
Huang W, Zheng X, Huang Q, Weng D, Yao S, Zhou C, Li Q, Hu Y, Xu W, Huang K
The American journal of pathology 2023 May;193(5):567-578
The American journal of pathology 2023 May;193(5):567-578
A human dynein heavy chain mutation impacts cortical progenitor cells causing developmental defects, reduced brain size and altered brain architecture.
Romero DM, Zaidi D, Cifuentes-Diaz C, Maillard C, Grannec G, Selloum M, Birling MC, Bahi-Buisson N, Francis F
Neurobiology of disease 2023 May;180:106085
Neurobiology of disease 2023 May;180:106085
Ischemic accumulation of succinate induces Cdc42 succinylation and inhibits neural stem cell proliferation after cerebral ischemia/reperfusion.
Huang LY, Ma JY, Song JX, Xu JJ, Hong R, Fan HD, Cai H, Wang W, Wang YL, Hu ZL, Shen JG, Qi SH
Neural regeneration research 2023 May;18(5):1040-1045
Neural regeneration research 2023 May;18(5):1040-1045
Pgp3 protein of Chlamydia trachomatis inhibits apoptosis via HO-1 upregulation mediated by PI3K/Akt activation.
Shu M, Bu J, Lei W, Chen L, Zhou Z, Lu C, Chen C, Li Z
Microbial pathogenesis 2023 May;178:106056
Microbial pathogenesis 2023 May;178:106056
Klotho protects against aged myocardial cells by attenuating ferroptosis.
Xiong X, Wang G, Wang Y, Zhang T, Bao Y, Wang K, Ainiwaer D, Sun Z
Experimental gerontology 2023 May;175:112157
Experimental gerontology 2023 May;175:112157
N6-Methyladenosine-Mediated Up-Regulation of FZD10 Regulates Liver Cancer Stem Cells' Properties and Lenvatinib Resistance Through WNT/β-Catenin and Hippo Signaling Pathways.
Wang J, Yu H, Dong W, Zhang C, Hu M, Ma W, Jiang X, Li H, Yang P, Xiang D
Gastroenterology 2023 May;164(6):990-1005
Gastroenterology 2023 May;164(6):990-1005
In vivo anti-hyperuricemia and anti-gouty arthritis effects of the ethanol extract from Amomumvillosum Lour.
Dong L, Zhang S, Chen L, Lu J, Zhao F, Long T, Wen J, Huang J, Mao Y, Qi Z, Zhang J, Li L, Dong Y
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 May;161:114532
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 May;161:114532
A low-salt diet with candesartan administration is associated with acute kidney injury in nephritis by increasing nitric oxide.
Yu Y, Wang P, Ren Z, Xue Y, Jia Y, Wang W, Liu M, Pan K, Xiao L, Ji D, Wang X
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 May;161:114484
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 May;161:114484
Magnolol improves Alzheimer's disease-like pathologies and cognitive decline by promoting autophagy through activation of the AMPK/mTOR/ULK1 pathway.
Wang X, Jia J
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 May;161:114473
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 May;161:114473
Autophagy inhibition and ferroptosis activation during atherosclerosis: Hypoxia-inducible factor 1α inhibitor PX-478 alleviates atherosclerosis by inducing autophagy and suppressing ferroptosis in macrophages.
Hu G, Yuan Z, Wang J
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 May;161:114333
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 May;161:114333
Virulence assessment of four Glaesserella parasuis strains isolated in Liaoning province of China.
Yan P, Jia YC, Zhang XL, Zhou YY, Guo Y, Yin RL, Yuan J, Wang LX, Guo ZB, Wang JY, Wang X, Yin RH
Research in veterinary science 2023 May;158:226-234
Research in veterinary science 2023 May;158:226-234
Chemoproteomics reveals arctigenin as a phagophore-closure blocker via targeting ESCRT-I subunit VPS28.
Han J, Yu Y, Li S, Miao R, Cheng W, Wei H
Bioorganic chemistry 2023 May;134:106457
Bioorganic chemistry 2023 May;134:106457
An ultrasensitive GSH-specific fluorescent probe unveils celastrol-induced ccRCC ferroptosis.
Li H, Deng C, Zhu N, Zhang C, Zeng Q, Qin L
Bioorganic chemistry 2023 May;134:106454
Bioorganic chemistry 2023 May;134:106454
NSUN2-mediated m(5) C RNA methylation dictates retinoblastoma progression through promoting PFAS mRNA stability and expression.
Zuo S, Li L, Wen X, Gu X, Zhuang A, Li R, Ye F, Ge S, Fan X, Fan J, Chai P, Lu L
Clinical and translational medicine 2023 May;13(5):e1273
Clinical and translational medicine 2023 May;13(5):e1273
TREM2 Insufficiency Protects against Pulmonary Fibrosis by Inhibiting M2 Macrophage Polarization.
Luo Q, Deng D, Li Y, Shi H, Zhao J, Qian Q, Wang W, Cai J, Yu W, Liu J
International immunopharmacology 2023 May;118:110070
International immunopharmacology 2023 May;118:110070
Baicalein ameliorates Alzheimer's disease via orchestration of CX3CR1/NF-κB pathway in a triple transgenic mouse model.
Xie XM, Hao JJ, Shi JZ, Zhou YF, Liu PF, Wang F, Zheng XM, Yu XY, Wang CC, Yan Y, Du GH, Song JK, He YY, Pang XB
International immunopharmacology 2023 May;118:109994
International immunopharmacology 2023 May;118:109994
Syringaresinol attenuates osteoarthritis via regulating the NF-κB pathway.
Wang X, Wang D, Deng B, Yan L
International immunopharmacology 2023 May;118:109982
International immunopharmacology 2023 May;118:109982
Stabilization of estrogen receptor α by USP37 contributes to the progression of breast cancer.
Cao J, Wang X, Wang S, Chen Z, Tang J
Cancer science 2023 May;114(5):2041-2052
Cancer science 2023 May;114(5):2041-2052
Effect of High-Intensity Interval Training on Fatty Infiltration After Delayed Rotator Cuff Repair in a Mouse Model.
Zhou H, Wang Z, Chen C, Hu H, Jiang B, Yin Y, Zhang K, Shen M, Wu S
Orthopaedic journal of sports medicine 2023 May;11(5):23259671231170192
Orthopaedic journal of sports medicine 2023 May;11(5):23259671231170192
A Novel Role for RILP in Regulating Osteoclastogenesis and Bone Resorption.
Wu B, Shang J, Lin S, Jiang N, Xing B, Peng R, Xu X, Lu H
Laboratory investigation; a journal of technical methods and pathology 2023 May;103(5):100067
Laboratory investigation; a journal of technical methods and pathology 2023 May;103(5):100067
BX795, a kinase inhibitor, inhibit duck plague virus infection via targeting US3 kinase.
Tian Y, Tian B, Wang M, Cai D, Cheng A, Zhang W, Wu Y, Yang Q, Ou X, Sun D, Zhang S, Mao S, Zhao X, Huang J, Gao Q, Zhu D, Jia R, Chen S, Liu M
Poultry science 2023 May;102(5):102597
Poultry science 2023 May;102(5):102597
Orai1 is an Entotic Ca(2+) Channel for Non-Apoptotic Cell Death, Entosis in Cancer Development.
Lee AR, Park CY
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 May;10(14):e2205913
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 May;10(14):e2205913
Malic Enzyme 1 as a Novel Anti-Ferroptotic Regulator in Hepatic Ischemia/Reperfusion Injury.
Fang X, Zhang J, Li Y, Song Y, Yu Y, Cai Z, Lian F, Yang J, Min J, Wang F
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 May;10(13):e2205436
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 May;10(13):e2205436
[Effects of Peroxisome Proliferator-Activated Receptor γ on Modulating Angiopoietin-Like Protein 4 Synthesis in Caco-2 Cells Exposed to Clostridium butyricum].
Zhao X, Huang HS, Shi SR
Molekuliarnaia biologiia 2023 May-Jun;57(3):501-502
Molekuliarnaia biologiia 2023 May-Jun;57(3):501-502
Bisphenol A induces testicular oxidative stress in mice leading to ferroptosis.
Li L, Wang MY, Jiang HB, Guo CR, Zhu XD, Yao XQ, Zeng WW, Zhao Y, Chi LK
Asian journal of andrology 2023 May-Jun;25(3):375-381
Asian journal of andrology 2023 May-Jun;25(3):375-381
Characterization of the protein expression and localization of hnRNP family members during murine spermatogenesis.
Wang XL, Li JM, Yuan SQ
Asian journal of andrology 2023 May-Jun;25(3):314-321
Asian journal of andrology 2023 May-Jun;25(3):314-321
Resistance to anti-HER2 therapy associated with the TSC2 nonsynonymous variant c.4349 C > G (p.Pro1450Arg) is reversed by CDK4/6 inhibitor in HER2-positive breast cancer.
Yang Z, Feng J, Jing J, Huang Y, Ye WW, Lei L, Wang XJ, Cao WM
NPJ breast cancer 2023 May 9;9(1):36
NPJ breast cancer 2023 May 9;9(1):36
Involvement of canonical Wnt/β-catenin signaling in the extinction of auditory fear conditioning in male mice.
Xu N, Geng L, Yan X, Niu A, Yu H, Su B
Behavioural brain research 2023 May 8;445:114378
Behavioural brain research 2023 May 8;445:114378
miR-183-5p overexpression orchestrates collective invasion in salivary adenoid cystic carcinoma through the FAT1/YAP1 signaling pathway.
Chen BJ, Jiang J, Li T, Jiang HJ, Liang XH, Tang YL
Biochemical and biophysical research communications 2023 May 7;655:127-137
Biochemical and biophysical research communications 2023 May 7;655:127-137
KLF9 Promotes Osteogenic Differentiation of Dental Stem Cells by Negatively Regulating Notch1 Mediated Signaling Pathway.
Zhao X, Mai Z, Lu Y, Cui L, Yu J
Frontiers in bioscience (Landmark edition) 2023 May 6;28(5):85
Frontiers in bioscience (Landmark edition) 2023 May 6;28(5):85
MicroRNA-143 acts as a tumor suppressor through Musashi-2/DLL1/Notch1 and Musashi-2/Snail1/MMPs axes in acute myeloid leukemia.
Li F, Han Y, Chen R, Jiang Y, Chen C, Wang X, Zhou J, Xu Q, Jiang S, Zhang S, Yu K, Zhang S
Journal of translational medicine 2023 May 6;21(1):309
Journal of translational medicine 2023 May 6;21(1):309
Losartan attenuates acetic acid enema-induced visceral hypersensitivity by inhibiting the ACE1/Ang II/AT1 receptor axis in enteric glial cells.
Sun Y, Liu X, Wang L, Li L, Quan X, Shi H, Wang T, Mei L, Chen Y, Zhang Y, Li J, Meng R, Wang J, Dai F
European journal of pharmacology 2023 May 5;946:175650
European journal of pharmacology 2023 May 5;946:175650
TMEM106B regulates microglial proliferation and survival in response to demyelination.
Zhang T, Pang W, Feng T, Guo J, Wu K, Nunez Santos M, Arthanarisami A, Nana AL, Nguyen Q, Kim PJ, Jankowsky JL, Seeley WW, Hu F
Science advances 2023 May 5;9(18):eadd2676
Science advances 2023 May 5;9(18):eadd2676
Differential regulation of ATP hydrolysis of RIG-I-like receptors by transactivation response RNA-binding protein.
Chunhaphinyokul B, Hosokai E, Miyamoto M, Komuro A
Bioscience reports 2023 May 5;43(5)
Bioscience reports 2023 May 5;43(5)
Discovery of acridine-based LSD1 inhibitors as immune activators targeting LSD1 in gastric cancer.
Liu HM, Xiong XP, Wu JW, Chen HX, Zhou Y, Ji SK, Dai XJ, Zheng YC, Liu HM
European journal of medicinal chemistry 2023 May 5;251:115255
European journal of medicinal chemistry 2023 May 5;251:115255
The mechanism of STING autoinhibition and activation.
Liu S, Yang B, Hou Y, Cui K, Yang X, Li X, Chen L, Liu S, Zhang Z, Jia Y, Xie Y, Xue Y, Li X, Yan B, Wu C, Deng W, Qi J, Lu D, Gao GF, Wang P, Shang G
Molecular cell 2023 May 4;83(9):1502-1518.e10
Molecular cell 2023 May 4;83(9):1502-1518.e10
TMT-based quantitative proteomic analysis of spheroid cells of endometrial cancer possessing cancer stem cell properties.
Cao M, Liu Z, You D, Pan Y, Zhang Q
Stem cell research & therapy 2023 May 4;14(1):119
Stem cell research & therapy 2023 May 4;14(1):119
Intracellular Vimentin Regulates the Formation of Classical Swine Fever Virus Replication Complex through Interaction with NS5A Protein.
Cheng Y, Lou JX, Liu YY, Liu CC, Chen J, Yang MC, Ye YB, Go YY, Zhou B
Journal of virology 2023 May 31;97(5):e0177022
Journal of virology 2023 May 31;97(5):e0177022
Interplay between Furin and Sialoglycans in Modulating Adeno-Associated Viral Cell Entry.
Smith TJ, Fusco RM, Elmore ZC, Asokan A
Journal of virology 2023 May 31;97(5):e0009323
Journal of virology 2023 May 31;97(5):e0009323
MALAT1 participates in the role of platelet-rich plasma exosomes in promoting wound healing of diabetic foot ulcer.
Chen C, Wang Q, Li D, Qi Z, Chen Y, Wang S
International journal of biological macromolecules 2023 May 31;238:124170
International journal of biological macromolecules 2023 May 31;238:124170
SCARECROW maintains the stem cell niche in Arabidopsis roots by ensuring telomere integrity.
Wang B, Shi X, Gao J, Liao R, Fu J, Bai J, Cui H
Plant physiology 2023 May 31;192(2):1115-1131
Plant physiology 2023 May 31;192(2):1115-1131
Akt2 deficiency alleviates oxidative stress in the heart and liver via up-regulating SIRT6 during high-fat diet-induced obesity.
Kong W, Peng Y, Ji C, Liu Z, Gao S, Zhang Y, Chen J, Li X, Bao M, Zhang Y, Jiang Q, Wang F, Li Z, Bian X, Ye J
Clinical science (London, England : 1979) 2023 May 31;137(10):823-841
Clinical science (London, England : 1979) 2023 May 31;137(10):823-841
MYO10 regulates genome stability and cancer inflammation through mediating mitosis.
Mayca Pozo F, Geng X, Miyagi M, Amin AL, Huang AY, Zhang Y
Cell reports 2023 May 30;42(5):112531
Cell reports 2023 May 30;42(5):112531
16p11.2 haploinsufficiency reduces mitochondrial biogenesis in brain endothelial cells and alters brain metabolism in adult mice.
Béland-Millar A, Kirby A, Truong Y, Ouellette J, Yandiev S, Bouyakdan K, Pileggi C, Naz S, Yin M, Carrier M, Kotchetkov P, St-Pierre MK, Tremblay MÈ, Courchet J, Harper ME, Alquier T, Messier C, Shuhendler AJ, Lacoste B
Cell reports 2023 May 30;42(5):112485
Cell reports 2023 May 30;42(5):112485
CX3CR1(hi) macrophages sustain metabolic adaptation by relieving adipose-derived stem cell senescence in visceral adipose tissue.
Zhou Z, Zhang H, Tao Y, Jie H, Zhao J, Zang J, Li H, Wang Y, Wang T, Zhao H, Li Y, Guo C, Zhu F, Mao H, Zhang L, Liu F, Wang Q
Cell reports 2023 May 30;42(5):112424
Cell reports 2023 May 30;42(5):112424
β-Hydroxy-β-methyl Butyrate Regulates the Lipid Metabolism, Mitochondrial Function, and Fat Browning of Adipocytes.
Duan G, Zheng C, Yu J, Zhang P, Wan M, Zheng J, Duan Y
Nutrients 2023 May 30;15(11)
Nutrients 2023 May 30;15(11)
The mechanisms to dispose of misfolded proteins in the endoplasmic reticulum of adipocytes.
Wu SA, Shen C, Wei X, Zhang X, Wang S, Chen X, Torres M, Lu Y, Lin LL, Wang HH, Hunter AH, Fang D, Sun S, Ivanova MI, Lin Y, Qi L
Nature communications 2023 May 30;14(1):3132
Nature communications 2023 May 30;14(1):3132
ARL6IP1 mediates small-molecule-induced alleviation of Alzheimer pathology through FXR1-dependent BACE1 translation initiation.
Zhou GF, Tang J, Ma YL, Fu X, Liu JY, Yang RZ, Zhang HS, Cai XH, Wang JW, Xie XY, Song L, Luo B, Chen J, Chen L, Deng XJ, Chen GJ
Proceedings of the National Academy of Sciences of the United States of America 2023 May 30;120(22):e2220148120
Proceedings of the National Academy of Sciences of the United States of America 2023 May 30;120(22):e2220148120
Hypermetabolism in mice carrying a near-complete human chromosome 21.
Sarver DC, Xu C, Rodriguez S, Aja S, Jaffe AE, Gao FJ, Delannoy M, Periasamy M, Kazuki Y, Oshimura M, Reeves RH, Wong GW
eLife 2023 May 30;12
eLife 2023 May 30;12
Epsin1-mediated exosomal sorting of Dll4 modulates the tubular-macrophage crosstalk in diabetic nephropathy.
Liu JL, Zhang L, Huang Y, Li XH, Liu YF, Zhang SM, Zhao YE, Chen XJ, Liu Y, He LY, Dong Z, Liu FY, Sun L, Xiao L
Molecular therapy : the journal of the American Society of Gene Therapy 2023 May 3;31(5):1451-1467
Molecular therapy : the journal of the American Society of Gene Therapy 2023 May 3;31(5):1451-1467
Unraveling the potential of senescence-related genes in guiding clinical therapy of lung adenocarcinoma patients.
Liu C, Wei X
Functional & integrative genomics 2023 May 29;23(2):188
Functional & integrative genomics 2023 May 29;23(2):188
VSTM2L contributes to anoikis resistance and acts as a novel biomarker for metastasis and clinical outcome in ovarian cancer.
Li Y, Zhang J, Cai Y, Liu H, Yang W, Xu Y, Huang M
Biochemical and biophysical research communications 2023 May 28;658:107-115
Biochemical and biophysical research communications 2023 May 28;658:107-115
Dengue Virus 2 NS2B Targets MAVS and IKKε to Evade the Antiviral Innate Immune Response.
Nie Y, Deng D, Mou L, Long Q, Chen J, Wu J
Journal of microbiology and biotechnology 2023 May 28;33(5):600-606
Journal of microbiology and biotechnology 2023 May 28;33(5):600-606
Pulsatilla Decoction and its bioactive component β-peltatin induce G2/M cell cycle arrest and apoptosis in pancreatic cancer.
Wu R, Xi Z, Liu M, Ren H, Dai R, Jiang X, Nik Nabil WN, Wang Y, Feng J, Chai Q, Dong Q, Xu H
Chinese medicine 2023 May 28;18(1):61
Chinese medicine 2023 May 28;18(1):61
LncRNA CASC19 promotes gastric cancer progression through preventing CREB1 protein ubiquitin/proteasome-dependent degradation.
Wang S, Qiao C, Li J, Liu S, Li P
Carcinogenesis 2023 May 27;44(3):209-220
Carcinogenesis 2023 May 27;44(3):209-220
The Nrf2/HMGB1/NF-κB axis modulates chondrocyte apoptosis and extracellular matrix degradation in osteoarthritis.
Li W, Tao C, Mao M, Zhu K
Acta biochimica et biophysica Sinica 2023 May 26;55(5):818-830
Acta biochimica et biophysica Sinica 2023 May 26;55(5):818-830
RSL1D1 knockdown induces ferroptosis and mediates ferrous iron accumulation in senescent cells by inhibiting FTH1 mRNA stability.
Jin Y, Zhao L, Wang S, Zhang X, Quan J, Lin Z, Piao J
Carcinogenesis 2023 May 26;44(2):129-142
Carcinogenesis 2023 May 26;44(2):129-142
Genetic and protein interaction studies between the ciliary dyslexia candidate genes DYX1C1 and DCDC2.
Bieder A, Chandrasekar G, Wason A, Erkelenz S, Gopalakrishnan J, Kere J, Tapia-Páez I
BMC molecular and cell biology 2023 May 26;24(1):20
BMC molecular and cell biology 2023 May 26;24(1):20
NEK2 promotes esophageal squamous cell carcinoma cell proliferation, migration and invasion through the Wnt/β-catenin signaling pathway.
Guo D, Yao W, Du X, Dong J, Zhang X, Shen W, Zhu S
Discover oncology 2023 May 26;14(1):80
Discover oncology 2023 May 26;14(1):80
Metformin promotes female germline stem cell proliferation by upregulating Gata-binding protein 2 with histone β-hydroxybutyrylation.
Wang X, Tian GG, Cheng W, Yu X, Li X, Wu J
Stem cell research & therapy 2023 May 26;14(1):144
Stem cell research & therapy 2023 May 26;14(1):144
Discovery of Potent and Wild-Type-Sparing Fourth-Generation EGFR Inhibitors for Treatment of Osimertinib-Resistance NSCLC.
Dong H, Ye X, Zhu Y, Shen H, Shen H, Chen W, Ji M, Zheng M, Wang K, Cai Z, Sun H, Xiao Y, Yang P
Journal of medicinal chemistry 2023 May 25;66(10):6849-6868
Journal of medicinal chemistry 2023 May 25;66(10):6849-6868
Tricyclic antidepressants induce liver inflammation by targeting NLRP3 inflammasome activation.
Mu W, Xu G, Wang Z, Li Q, Sun S, Qin Q, Li Z, Shi W, Dai W, Zhan X, Wang J, Bai Z, Xiao X
Cell communication and signaling : CCS 2023 May 25;21(1):123
Cell communication and signaling : CCS 2023 May 25;21(1):123
Dietary Isoquercetin Reduces Hepatic Cholesterol and Triglyceride in NAFLD Mice by Modulating Bile Acid Metabolism via Intestinal FXR-FGF15 Signaling.
Zhang C, Shi Z, Lei H, Wu F, Chen C, Cao Z, Song Y, Zhang C, Zhou J, Lu Y, Zhang L
Journal of agricultural and food chemistry 2023 May 24;71(20):7723-7733
Journal of agricultural and food chemistry 2023 May 24;71(20):7723-7733
Poly (ADP-ribose) polymerases 16 triggers pathological cardiac hypertrophy via activating IRE1α-sXBP1-GATA4 pathway.
Su H, Xu J, Su Z, Xiao C, Wang J, Zhong W, Meng C, Yang D, Zhu Y
Cellular and molecular life sciences : CMLS 2023 May 23;80(6):161
Cellular and molecular life sciences : CMLS 2023 May 23;80(6):161
Discovering a Reversible Male Contraceptive Agent Derived from Lonidamine.
Gong S, Zhu S, Zhou P, Cheng CY, Li W, Yao W, Sun F
ACS omega 2023 May 23;8(20):18245-18254
ACS omega 2023 May 23;8(20):18245-18254
UQCRFS1 serves as a prognostic biomarker and promotes the progression of ovarian cancer.
Sun Q, Li J, Dong H, Zhan J, Xiong X, Ding J, Li Y, He L, Wang J
Scientific reports 2023 May 23;13(1):8335
Scientific reports 2023 May 23;13(1):8335
Brain-Derived Estrogen Regulates Neurogenesis, Learning and Memory with Aging in Female Rats.
Huang Y, Sun W, Gao F, Ma H, Yuan T, Liu Z, Liu H, Hu J, Bai J, Zhang X, Wang R
Biology 2023 May 23;12(6)
Biology 2023 May 23;12(6)
Base editing-mediated one-step inactivation of the Dnmt gene family reveals critical roles of DNA methylation during mouse gastrulation.
Li Q, Lu J, Yin X, Chang Y, Wang C, Yan M, Feng L, Cheng Y, Gao Y, Xu B, Zhang Y, Wang Y, Cui G, Xu L, Sun Y, Zeng R, Li Y, Jing N, Xu GL, Wu L, Tang F, Li J
Nature communications 2023 May 22;14(1):2922
Nature communications 2023 May 22;14(1):2922
FAM210A Regulates Mitochondrial Translation and Maintains Cardiac Mitochondrial Homeostasis.
Wu J, Subbaiah KCV, Hedaya O, Chen S, Munger J, Tang WHW, Yan C, Yao P
bioRxiv : the preprint server for biology 2023 May 22;
bioRxiv : the preprint server for biology 2023 May 22;
Azelaic Acid Regulates the Renin-Angiotensin System and Improves Colitis Based on Network Pharmacology and Experimentation.
Liao Y, Wu X, Luo W, Chen J, Huang Y, Ma K, Zhang C, Wang J, Yang Y, Deng M, Wang X
ACS omega 2023 May 2;8(17):15217-15228
ACS omega 2023 May 2;8(17):15217-15228
Dietary intake of α-ketoglutarate ameliorates α-synuclein pathology in mouse models of Parkinson's disease.
Zhang W, Ding L, Zhang M, Zheng S, Ma R, Gong J, Mao H, Xu H, Xu P, Zhang Y
Cellular and molecular life sciences : CMLS 2023 May 19;80(6):155
Cellular and molecular life sciences : CMLS 2023 May 19;80(6):155
FBXW7β loss-of-function enhances FASN-mediated lipogenesis and promotes colorectal cancer growth.
Wei W, Qin B, Wen W, Zhang B, Luo H, Wang Y, Xu H, Xie X, Liu S, Jiang X, Wang M, Tang Q, Zhang J, Yang R, Fan Z, Lyu H, Lin J, Li K, Lee MH
Signal transduction and targeted therapy 2023 May 19;8(1):187
Signal transduction and targeted therapy 2023 May 19;8(1):187
Epigenetically silenced lncRNA SNAI3-AS1 promotes ferroptosis in glioma via perturbing the m(6)A-dependent recognition of Nrf2 mRNA mediated by SND1.
Zheng J, Zhang Q, Zhao Z, Qiu Y, Zhou Y, Wu Z, Jiang C, Wang X, Jiang X
Journal of experimental & clinical cancer research : CR 2023 May 19;42(1):127
Journal of experimental & clinical cancer research : CR 2023 May 19;42(1):127
Establishment of highly metastatic ovarian cancer model with omental tropism via in vivo selection.
Ying F, Guo J, Gao X, Huang L, Gao L, Cai J, Wang Z
iScience 2023 May 19;26(5):106719
iScience 2023 May 19;26(5):106719
Piezo1 induces endothelial responses to shear stress via soluble adenylyl Cyclase-IP(3)R2 circuit.
Santana Nunez D, Malik AB, Lee Q, Ahn SJ, Coctecon-Murillo A, Lazarko D, Levitan I, Mehta D, Komarova YA
iScience 2023 May 19;26(5):106661
iScience 2023 May 19;26(5):106661
C9ORF72 suppresses JAK-STAT mediated inflammation.
Pang W, Hu F
iScience 2023 May 19;26(5):106579
iScience 2023 May 19;26(5):106579
Isoflavones Mediate Dendritogenesis Mainly through Estrogen Receptor α.
Ariyani W, Amano I, Koibuchi N
International journal of molecular sciences 2023 May 19;24(10)
International journal of molecular sciences 2023 May 19;24(10)
ERK and USP5 govern PD-1 homeostasis via deubiquitination to modulate tumor immunotherapy.
Xiao X, Shi J, He C, Bu X, Sun Y, Gao M, Xiang B, Xiong W, Dai P, Mao Q, Xing X, Yao Y, Yu H, Xu G, Li S, Ren Y, Chen B, Jiang C, Meng G, Lee YR, Wei W, Freeman GJ, Xie C, Zhang J
Nature communications 2023 May 19;14(1):2859
Nature communications 2023 May 19;14(1):2859
Insight into Pathogenic Mechanism Underlying the Hereditary Cataract Caused by βB2-G149V Mutation.
Wu J, Chen S, Xu J, Xu W, Zheng S, Tian Q, Luo C, Chen X, Shentu X
Biomolecules 2023 May 19;13(5)
Biomolecules 2023 May 19;13(5)
Characterization of an allosteric inhibitor of fungal-specific C-24 sterol methyltransferase to treat Candida albicans infections.
Jin X, Hou X, Wang X, Zhang M, Chen J, Song M, Zhang J, Zheng H, Chang W, Lou H
Cell chemical biology 2023 May 18;30(5):553-568.e7
Cell chemical biology 2023 May 18;30(5):553-568.e7
LncRNA-PVT1 was identified as a key regulator for TMZ resistance and STAT-related pathway in glioma.
Chen Y, Ma F, Zhang Z, Guo Y, Shen H, Chen H
BMC cancer 2023 May 18;23(1):455
BMC cancer 2023 May 18;23(1):455
Development and validation of a selenium metabolism regulators associated prognostic model for hepatocellular carcinoma.
Sun H, Long J, Zuo B, Li Y, Song Y, Yu M, Xun Z, Wang Y, Wang X, Sang X, Zhao H
BMC cancer 2023 May 18;23(1):451
BMC cancer 2023 May 18;23(1):451
Profiling the impact of the promoters on CRISPR-Cas12a system in human cells.
Li J, Liang Q, Zhou H, Zhou M, Huang H
Cellular & molecular biology letters 2023 May 17;28(1):41
Cellular & molecular biology letters 2023 May 17;28(1):41
Comprehensive analysis of ferroptosis-related genes for clinical and biological significance in hepatocellular carcinoma.
Wu Q, Tan Z, Xiong Y, Gu C, Zhou J, Yang H, Zhou J
Discover oncology 2023 May 17;14(1):69
Discover oncology 2023 May 17;14(1):69
Crosstalk between the JAK2 and TGF-β1 signaling pathways in scleroderma-related interstitial lung disease targeted by baricitinib.
Wang D, Wei Y, Xu L, Zhang J
Advances in rheumatology (London, England) 2023 May 16;63(1):22
Advances in rheumatology (London, England) 2023 May 16;63(1):22
SDMA attenuates renal tubulointerstitial fibrosis through inhibition of STAT4.
Wang Y, Wu M, Chen D, Tan B, Lin P, Huang D, Ye C
Journal of translational medicine 2023 May 16;21(1):326
Journal of translational medicine 2023 May 16;21(1):326
Gene expression of TRPMLs and its regulation by pathogen stimulation.
Xia Z, Xie L, Li D, Hong X, Qin C
Gene 2023 May 15;864:147291
Gene 2023 May 15;864:147291
Discovery of 4-oxo-4,5-dihydropyrazolo[1,5-a]quinoxaline-7-carboxamide derivatives as PI3Kα inhibitors via virtual screening and docking-based structure optimization.
Gu D, Zhang M, Cai L, Wang C, Zhou YB, Li J, Sheng R
Bioorganic & medicinal chemistry 2023 May 15;86:117288
Bioorganic & medicinal chemistry 2023 May 15;86:117288
Melatonin ameliorates acute lung injury caused by paraquat poisoning by promoting PINK1 and BNIP3 expression.
Yin Y, Shen H
Toxicology 2023 May 15;490:153506
Toxicology 2023 May 15;490:153506
Suppression of SIRT1/FXR signaling pathway contributes to oleanolic acid-induced liver injury.
Liao S, Fu X, Huang J, Wang Y, Lu Y, Zhou S
Toxicology and applied pharmacology 2023 May 15;467:116509
Toxicology and applied pharmacology 2023 May 15;467:116509
Guanine nucleotide exchange factor T exerts the cancer-promoting function in cholangiocarcinoma by enhancing the Wnt-GSK-3β-β-catenin cascade via regulation of Rac1/Cdc42.
Wang X, Zhang X, Sun J, Sun Y, Zhang Y, He L, Wang P, Li F, Sun C
Toxicology and applied pharmacology 2023 May 15;467:116492
Toxicology and applied pharmacology 2023 May 15;467:116492
LMNB1 deletion in ovarian cancer inhibits the proliferation and metastasis of tumor cells through PI3K/Akt pathway.
Dong J, Ru Y, Zhai L, Gao Y, Guo X, Chen B, Lv X
Experimental cell research 2023 May 15;426(2):113573
Experimental cell research 2023 May 15;426(2):113573
Quiescent Ovarian Cancer Cells Secrete Follistatin to Induce Chemotherapy Resistance in Surrounding Cells in Response to Chemotherapy.
Cole AJ, Panesso-Gómez S, Shah JS, Ebai T, Jiang Q, Gumusoglu-Acar E, Bello MG, Vlad A, Modugno F, Edwards RP, Buckanovich RJ
Clinical cancer research : an official journal of the American Association for Cancer Research 2023 May 15;29(10):1969-1983
Clinical cancer research : an official journal of the American Association for Cancer Research 2023 May 15;29(10):1969-1983
Role of selenoprotein M knockdown in the melatonin antagonism of nickel-induced apoptosis and endoplasmic reticulum stress in mouse heart.
Zhang X, Gai X, Xu L, Ma W, Liu Q, Shi B, Fang C, Cai J, Zhang Z
Journal of Zhejiang University. Science. B 2023 May 15;24(5):406-417
Journal of Zhejiang University. Science. B 2023 May 15;24(5):406-417
Interaction of Nmi and IFP35 Promotes Mutual Protein Stabilization and IRF3 and IRF7 Degradation to Suppress Type I IFN Production in Teleost Fish.
Li L, Chen SN, Wang KL, Li N, Pang AN, Liu LH, Li B, Hou J, Wang S, Nie P
Journal of immunology (Baltimore, Md. : 1950) 2023 May 15;210(10):1494-1507
Journal of immunology (Baltimore, Md. : 1950) 2023 May 15;210(10):1494-1507
FOXA2 plays a critical role in hepatocellular carcinoma progression and lenvatinib-associated drug resistance.
Wang Z, Shen J, Chen C, Wen T, Li C
Bioscience trends 2023 May 15;17(2):136-147
Bioscience trends 2023 May 15;17(2):136-147
The pathogenesis of common Gjb2 mutations associated with human hereditary deafness in mice.
Li Q, Cui C, Liao R, Yin X, Wang D, Cheng Y, Huang B, Wang L, Yan M, Zhou J, Zhao J, Tang W, Wang Y, Wang X, Lv J, Li J, Li H, Shu Y
Cellular and molecular life sciences : CMLS 2023 May 13;80(6):148
Cellular and molecular life sciences : CMLS 2023 May 13;80(6):148
The PI3K-Akt-mTOR pathway mediates renal pericyte-myofibroblast transition by enhancing glycolysis through HKII.
Chen L, Li X, Deng Y, Chen J, Huang M, Zhu F, Gao Z, Wu L, Hong Q, Feng Z, Cai G, Sun X, Bai X, Chen X
Journal of translational medicine 2023 May 13;21(1):323
Journal of translational medicine 2023 May 13;21(1):323
Effects of hunger on neuronal histone modifications slow aging in Drosophila.
Weaver KJ, Holt RA, Henry E, Lyu Y, Pletcher SD
Science (New York, N.Y.) 2023 May 12;380(6645):625-632
Science (New York, N.Y.) 2023 May 12;380(6645):625-632
Ethyl Gallate Inhibits Bovine Viral Diarrhea Virus by Promoting IFITM3 Expression, Lysosomal Acidification and Protease Activity.
Zhang L, Yang G, Wang J, Zhang J, Chen K, Xiong X, Zhu Y, Xu C, Wang J
International journal of molecular sciences 2023 May 12;24(10)
International journal of molecular sciences 2023 May 12;24(10)
Design, Synthesis and Antitumor Activity of 1H-indazole-3-amine Derivatives.
Wang C, Zhu M, Long X, Wang Q, Wang Z, Ouyang G
International journal of molecular sciences 2023 May 12;24(10)
International journal of molecular sciences 2023 May 12;24(10)
PRMT2 promotes RCC tumorigenesis and metastasis via enhancing WNT5A transcriptional expression.
Li Z, Chen C, Yong H, Jiang L, Wang P, Meng S, Chu S, Li Z, Guo Q, Zheng J, Bai J, Li H
Cell death & disease 2023 May 12;14(5):322
Cell death & disease 2023 May 12;14(5):322
Dysregulation of amino acid metabolism upon rapid depletion of cap-binding protein eIF4E.
Diamond PD, McGlincy NJ, Ingolia NT
bioRxiv : the preprint server for biology 2023 May 12;
bioRxiv : the preprint server for biology 2023 May 12;
Coaggregation of polyglutamine (polyQ) proteins is mediated by polyQ-tract interactions and impairs cellular proteostasis.
Hong JY, Wang JY, Yue HW, Zhang XL, Zhang SX, Jiang LL, Hu HY
Acta biochimica et biophysica Sinica 2023 May 11;55(5):736-748
Acta biochimica et biophysica Sinica 2023 May 11;55(5):736-748
Lactiplantibacillus plantarum attenuates Coxsackievirus B3-induced pancreatitis through the BAX/BCL2/CASP3 signaling pathway.
Yu X, Zhang Y, Pei K, Tan J, Tian H, Xu T, Liu F, Peng N, Huang Y, Huang X, Huang X, Wu J, Liu Q, Zeng L, Hua W, Huang X
Food & function 2023 May 11;14(9):4129-4142
Food & function 2023 May 11;14(9):4129-4142
Effect of Sublethal Concentrations of Metal Nanomaterials on Cell Energy Metabolism.
Liang C, Jiang Q, Liu Z, Yang J, Zhang J, Zhang S, Xin W
Toxics 2023 May 11;11(5)
Toxics 2023 May 11;11(5)
G Protein-Coupled Receptor 120 Mediates Host Defense against Clostridium perfringens Infection through Regulating NOD-like Receptor Family Pyrin Domain-Containing 3 Inflammasome Activation.
Liu Y, Lei YX, Li JW, Ma YZ, Wang XY, Meng FH, Wu YJ, Wang N, Liang J, Zhao CQ, Yang Y, Chen GX, Yu SX
Journal of agricultural and food chemistry 2023 May 10;71(18):7119-7130
Journal of agricultural and food chemistry 2023 May 10;71(18):7119-7130
Elsholtzia bodinieri Vaniot ameliorated acute lung injury in mice by regulating pyroptosis, inflammation, oxidative stress and macrophage polarization.
Jiang X, Sun J, Guo S, Zhao Z, Chen Y, Cao J, Liu Y, Cheng G, Tian L, Li Y
Journal of ethnopharmacology 2023 May 10;307:116232
Journal of ethnopharmacology 2023 May 10;307:116232
β-Hydroxybutyric acid upregulated by Suhuang antitussive capsule ameliorates cough variant asthma through GSK3β/AMPK-Nrf2 signal axis.
Jiang H, Bai Z, Ou Y, Liu H, Si Z, Liu Y, Liu X, Liu X, Zhang Z, Tan N
Journal of ethnopharmacology 2023 May 10;307:116013
Journal of ethnopharmacology 2023 May 10;307:116013
Descending serotonergic modulation from rostral ventromedial medulla to spinal trigeminal nucleus is involved in experimental occlusal interference-induced chronic orofacial hyperalgesia.
Mo SY, Xue Y, Li Y, Zhang YJ, Xu XX, Fu KY, Sessle BJ, Xie QF, Cao Y
The journal of headache and pain 2023 May 10;24(1):50
The journal of headache and pain 2023 May 10;24(1):50
Identification and validation of metabolism-related genes signature and immune infiltration landscape of rheumatoid arthritis based on machine learning.
Guo Z, Ma Y, Wang Y, Xiang H, Cui H, Fan Z, Zhu Y, Xing D, Chen B, Tao H, Guo Z, Wu X
Aging 2023 May 10;15(9):3807-3825
Aging 2023 May 10;15(9):3807-3825
Pharmaceutical SH2 domain-containing protein tyrosine phosphatase 2 inhibition suppresses primary and metastasized liver tumors by provoking hepatic innate immunity.
Liu JJ, Xin B, Du L, Chen L, Long Y, Feng GS
Hepatology (Baltimore, Md.) 2023 May 1;77(5):1512-1526
Hepatology (Baltimore, Md.) 2023 May 1;77(5):1512-1526
KIFC3 regulates progression of hepatocellular carcinoma via EMT and the AKT/mTOR pathway.
Lu S, Liu Y, Tian S, He Y, Dong W
Experimental cell research 2023 May 1;426(1):113564
Experimental cell research 2023 May 1;426(1):113564
Mitotic DNA damage promotes chromokinesin-mediated missegregation of polar chromosomes in cancer cells.
Novais-Cruz M, Pombinho A, Sousa M, Maia AF, Maiato H, Ferrás C
Molecular biology of the cell 2023 May 1;34(5):ar47
Molecular biology of the cell 2023 May 1;34(5):ar47
Accumulated precursors of specific GPI-anchored proteins upregulate GPI biosynthesis with ARV1.
Liu YS, Wang Y, Zhou X, Zhang L, Yang G, Gao XD, Murakami Y, Fujita M, Kinoshita T
The Journal of cell biology 2023 May 1;222(5)
The Journal of cell biology 2023 May 1;222(5)
A regulatory circuit comprising the CBP and SIRT7 regulates FAM134B-mediated ER-phagy.
Wang X, Jiang X, Li B, Zheng J, Guo J, Gao L, Du M, Weng X, Li L, Chen S, Zhang J, Fang L, Liu T, Wang L, Liu W, Neculai D, Sun Q
The Journal of cell biology 2023 May 1;222(5)
The Journal of cell biology 2023 May 1;222(5)
JNK-JUN-NCOA4 axis contributes to chondrocyte ferroptosis and aggravates osteoarthritis via ferritinophagy.
Sun K, Hou L, Guo Z, Wang G, Guo J, Xu J, Zhang X, Guo F
Free radical biology & medicine 2023 May 1;200:87-101
Free radical biology & medicine 2023 May 1;200:87-101
The role of ferroptosis mediated by Bmal1/Nrf2 in nicotine -induce injury of BTB integrity.
Zhang Z, Cheng J, Yang L, Li X, Hua R, Xu D, Jiang Z, Li Q
Free radical biology & medicine 2023 May 1;200:26-35
Free radical biology & medicine 2023 May 1;200:26-35
Role of nuclear factor of activated T Cells-1 in Sepsis-induced behavioral deficits in mice.
Jiang F, Guo Y, Hu L, Zhang M, Meng J, Si Y, Shi H
Brain research 2023 May 1;1806:148299
Brain research 2023 May 1;1806:148299
Cardiac-specific Trim44 knockout in rat attenuates isoproterenol-induced cardiac remodeling via inhibition of AKT/mTOR pathway.
Jiang XY, Guan FF, Ma JX, Dong W, Qi XL, Zhang X, Chen W, Gao S, Gao X, Pan S, Wang JZ, Ma YW, Zhang LF, Lu D
Disease models & mechanisms 2023 May 1;16(5)
Disease models & mechanisms 2023 May 1;16(5)
Targeting fibrinogen-like protein 1 enhances immunotherapy in hepatocellular carcinoma.
Lin M, He J, Zhang X, Sun X, Dong W, Zhang R, Xu Y, Lv L
The Journal of clinical investigation 2023 May 1;133(9)
The Journal of clinical investigation 2023 May 1;133(9)
FBXO11 amplifies type I interferon signaling to exert antiviral effects by facilitating the assemble of TRAF3-TBK1-IRF3 complex.
Gao L, Gao Y, Han K, Wang Z, Meng F, Liu J, Zhao X, Shao Y, Shen J, Sun W, Liu Y, Xu H, Du X, Li J, Qin FX
Journal of medical virology 2023 Mar;95(3):e28655
Journal of medical virology 2023 Mar;95(3):e28655
ZNFX1 antisense RNA1 promotes antiviral innate immune responses via modulating ZNFX1 function.
Jia X, Zhang M, Wang H, Cheng C, Li Q, Li Y, Kong L, Lan X, Wang Y, Liang X, Yuan S, Wang Y, Xu A
Journal of medical virology 2023 Mar;95(3):e28637
Journal of medical virology 2023 Mar;95(3):e28637
Exploring the mechanism of physcion-1-O-β-D-monoglucoside against acute lymphoblastic leukaemia based on network pharmacology and experimental validation.
Liu J, Yang Y, Zeng Y, Qin X, Guo L, Liu W
Heliyon 2023 Mar;9(3):e14009
Heliyon 2023 Mar;9(3):e14009
NETs promote ROS production to induce human amniotic epithelial cell apoptosis via ERK1/2 signaling in spontaneous preterm birth.
Hu M, Li H, Li G, Wang Y, Liu J, Zhang M, Shen D, Wang X
American journal of reproductive immunology (New York, N.Y. : 1989) 2023 Mar;89(3):e13656
American journal of reproductive immunology (New York, N.Y. : 1989) 2023 Mar;89(3):e13656
VPS35 promotes cell proliferation via EGFR recycling and enhances EGFR inhibitors response in gastric cancer.
Yu J, Feng H, Sang Q, Li F, Chen M, Yu B, Xu Z, Pan T, Wu X, Hou J, Zhu Z, Yan C, Su L, Li J, Liu B
EBioMedicine 2023 Mar;89:104451
EBioMedicine 2023 Mar;89:104451
Targeting CXCL5 in Pancreatic Cancer Cells Inhibits Cancer Xenograft Growth by Reducing Proliferation and Inhibiting EMT Progression.
Wang ZZ, Li XT, Li QJ, Zhou JX
Digestive diseases and sciences 2023 Mar;68(3):841-851
Digestive diseases and sciences 2023 Mar;68(3):841-851
Thiol oxidative stress-dependent degradation of transglutaminase2 via protein S-glutathionylation sensitizes 5-fluorouracil therapy in 5-fluorouracil-resistant colorectal cancer cells.
Li X, Ma Y, Wu J, Ni M, Chen A, Zhou Y, Dai W, Chen Z, Jiang R, Ling Y, Yao Q, Chen W
Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy 2023 Mar;67:100930
Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy 2023 Mar;67:100930
FOXK2 affects cancer cell response to chemotherapy by promoting nucleotide de novo synthesis.
Li Y, Chen J, Wang B, Xu Z, Wu C, Ma J, Song Q, Geng Q, Yu J, Pei H, Yao Y
Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy 2023 Mar;67:100926
Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy 2023 Mar;67:100926
Sclerostin antibody promotes bone formation through the Wnt/β-catenin signaling pathway in femoral trochlear after patellar instability.
Xu C, Ji G, Chen X, Yan L, Liang T, Liu J, Wang F
Connective tissue research 2023 Mar;64(2):148-160
Connective tissue research 2023 Mar;64(2):148-160
The Depletion of NAMPT Disturbs Mitochondrial Homeostasis and Causes Neuronal Degeneration in Mouse Hippocampus.
Shen C, Chen C, Wang T, Gao TY, Zeng M, Lu YB, Zhang WP
Molecular neurobiology 2023 Mar;60(3):1267-1280
Molecular neurobiology 2023 Mar;60(3):1267-1280
G3BP1 coordinates lysophagy activity to protect against compression-induced cell ferroptosis during intervertebral disc degeneration.
Li S, Liao Z, Yin H, Liu O, Hua W, Wu X, Zhang Y, Gao Y, Yang C
Cell proliferation 2023 Mar;56(3):e13368
Cell proliferation 2023 Mar;56(3):e13368
Knockdown of FGFR3 inhibits the proliferation, migration and invasion of intrahepatic cholangiocarcinoma.
Chen YH, Yang SH, Liu LX, Hu S, Wang XJ, Liao ZJ, Huan YF, He K, Zhang XW
Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 2023 Mar;55(3):400-406
Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 2023 Mar;55(3):400-406
Compound Kushen injection attenuates angiotensin II‑mediated heart failure by inhibiting the PI3K/Akt pathway.
Wang W, Liu D, Yang L, Chen L, Miao M, Liu Y, Yin Y, Wei M, Liu G, An Y, Zheng M
International journal of molecular medicine 2023 Mar;51(3)
International journal of molecular medicine 2023 Mar;51(3)
Angiotensin receptor blockade with olmesartan alleviates brain pathology in obese OLETF rats.
Rodriguez-Ortiz CJ, Thorwald MA, Rodriguez R, Mejias-Ortega M, Kieu Z, Maitra N, Hawkins C, Valenzuela J, Peng M, Nishiyama A, Ortiz RM, Kitazawa M
Clinical and experimental pharmacology & physiology 2023 Mar;50(3):228-237
Clinical and experimental pharmacology & physiology 2023 Mar;50(3):228-237
Circ_0056618 enhances PRRG4 expression by competitively binding to miR-411-5p to promote the malignant progression of colorectal cancer.
Zhang B, Cao W, Liu Y, Zhao Y, Liu C, Sun B
Molecular and cellular biochemistry 2023 Mar;478(3):503-516
Molecular and cellular biochemistry 2023 Mar;478(3):503-516
RASSF1A inhibits epithelial-mesenchymal transition of gastric cancer cells by downregulating P-JNK.
Bin Y, Deng W, Hu H, Zeng Q, Chen J, Xu Y, Dai Y, Liao A, Xiao W
Cell biology international 2023 Mar;47(3):573-583
Cell biology international 2023 Mar;47(3):573-583
Progranulin promotes proliferation, migration and invasion via the PI3K/Akt signalling pathway in a model of endometriosis.
Qin R, Zheng F, Qin W, Wang J, Ma N, Tian W, Li J, Liao M, Qin A
Reproductive biomedicine online 2023 Mar;46(3):425-435
Reproductive biomedicine online 2023 Mar;46(3):425-435
CD44 mediates hyaluronan to promote the differentiation of human amniotic mesenchymal stem cells into chondrocytes.
Xu Y, Wang AT, Xiao JH
Biotechnology letters 2023 Mar;45(3):411-422
Biotechnology letters 2023 Mar;45(3):411-422
Deubiquitinating enzyme USP11 promotes renal tubular cell senescence and fibrosis via inhibiting the ubiquitin degradation of TGF-β receptor II.
Ni JY, Wang X, Xie HY, Yang NH, Li JY, Sun XA, Guo HJ, Zhou L, Zhang W, Liu J, Lu LM
Acta pharmacologica Sinica 2023 Mar;44(3):584-595
Acta pharmacologica Sinica 2023 Mar;44(3):584-595
SZC-6, a small-molecule activator of SIRT3, attenuates cardiac hypertrophy in mice.
Li ZY, Lu GQ, Lu J, Wang PX, Zhang XL, Zou Y, Liu PQ
Acta pharmacologica Sinica 2023 Mar;44(3):546-560
Acta pharmacologica Sinica 2023 Mar;44(3):546-560
Glucose-mediated N-glycosylation of RPTPα affects its subcellular localization and Src activation.
Fang J, Zhang Y, Huang C, Lu R, Yu J, Chen R, Wang Y, Zhao X, Yu J, Huang J
Oncogene 2023 Mar;42(14):1058-1071
Oncogene 2023 Mar;42(14):1058-1071
BMAL1 collaborates with CLOCK to directly promote DNA double-strand break repair and tumor chemoresistance.
Zhang C, Chen L, Sun L, Jin H, Ren K, Liu S, Qian Y, Li S, Li F, Zhu C, Zhao Y, Liu H, Liu Y
Oncogene 2023 Mar;42(13):967-979
Oncogene 2023 Mar;42(13):967-979
ZD6474 Attenuates Fibrosis and Inhibits Neovascularization in Human Pterygium by Suppressing AKT-mTOR Signaling Pathway.
Liu W, Lin T, Gong L
Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 2023 Mar;39(2):128-138
Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 2023 Mar;39(2):128-138
Physalin A alleviates intervertebral disc degeneration via anti-inflammatory and anti-fibrotic effects.
Lu R, Xu H, Deng X, Wang Y, He Z, Xu S, Liang S, Huang X, You H, Guo F, Cheng P, Chen AM
Journal of orthopaedic translation 2023 Mar;39:74-87
Journal of orthopaedic translation 2023 Mar;39:74-87
The downregulation of HSP90-controlled CRALBP expression is associated with age-related vision attenuation.
Chen DD, Liu B, Wang Y, Jiang M, Shang G, Xue M, Jia X, Lang Y, Zhou G, Zhang F, Peng X, Hu Y
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Mar;37(3):e22832
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Mar;37(3):e22832
Stabilization of nuclear β-catenin by inhibiting KDM2A mediates cerebral ischemic tolerance.
Zuo Y, Zhan L, Wen H, Xue J, Tan Y, Sun W, Xu E
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Mar;37(3):e22796
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Mar;37(3):e22796
Treponema pallidum membrane protein Tp47 promotes angiogenesis through ROS-induced autophagy.
Li W, Xie L, Li QL, Xu QY, Lin LR, Liu LL, Yang TC
Journal of the European Academy of Dermatology and Venereology : JEADV 2023 Mar;37(3):558-572
Journal of the European Academy of Dermatology and Venereology : JEADV 2023 Mar;37(3):558-572
LAMP-2A ablation in hippocampal CA1 astrocytes confers cerebroprotection and ameliorates neuronal injury after global brain ischemia.
Fu HY, Cui Y, Li Q, Wang D, Li H, Yang L, Wang DJ, Zhou JW
Brain pathology (Zurich, Switzerland) 2023 Mar;33(2):e13114
Brain pathology (Zurich, Switzerland) 2023 Mar;33(2):e13114
HSP90β promotes osteoclastogenesis by dual-activation of cholesterol synthesis and NF-κB signaling.
Cheng HM, Xing M, Zhou YP, Zhang W, Liu Z, Li L, Zheng Z, Ma Y, Li P, Liu X, Li P, Xu X
Cell death and differentiation 2023 Mar;30(3):673-686
Cell death and differentiation 2023 Mar;30(3):673-686
STMN2 overexpression promotes cell proliferation and EMT in pancreatic cancer mediated by WNT/β-catenin signaling.
Shao M, Wang L, Zhang Q, Wang T, Wang S
Cancer gene therapy 2023 Mar;30(3):472-480
Cancer gene therapy 2023 Mar;30(3):472-480
Cancer-derived exosomal miR-375 targets DIP2C and promotes osteoblastic metastasis and prostate cancer progression by regulating the Wnt signaling pathway.
Liu Y, Yang C, Chen S, Liu W, Liang J, He S, Hui J
Cancer gene therapy 2023 Mar;30(3):437-449
Cancer gene therapy 2023 Mar;30(3):437-449
Abamectin causes cardiac dysfunction in carp via inhibiting redox equilibrium and resulting in immune inflammatory response and programmed cell death.
Zhao P, Wang Y, Yang Q, Yu G, Ma F, Dong J
Environmental science and pollution research international 2023 Mar;30(11):29494-29509
Environmental science and pollution research international 2023 Mar;30(11):29494-29509
Identifying Protein-Protein Interactions by Proximity Biotinylation with AirID and splitAirID.
Schaack GA, Sullivan OM, Mehle A
Current protocols 2023 Mar;3(3):e702
Current protocols 2023 Mar;3(3):e702
Histone acetyltransferase KAT2A modulates neural stem cell differentiation and proliferation by inducing degradation of the transcription factor PAX6.
Dong Z, He W, Lin G, Chen X, Cao S, Guan T, Sun Y, Zhang Y, Qi M, Guo B, Zhou Z, Zhuo R, Wu R, Liu M, Liu Y
The Journal of biological chemistry 2023 Mar;299(3):103020
The Journal of biological chemistry 2023 Mar;299(3):103020
The Rab GTPase-binding protein EHBP1L1 and its interactors CD2AP/CIN85 negatively regulate the length of primary cilia via actin remodeling.
Iwano T, Sobajima T, Takeda S, Harada A, Yoshimura SI
The Journal of biological chemistry 2023 Mar;299(3):102985
The Journal of biological chemistry 2023 Mar;299(3):102985
Acetylation stabilizes the signaling protein WISP2 by preventing its degradation to suppress the progression of acute myeloid leukemia.
Zhang H, Song W, Ma X, Yu M, Chen L, Tao Y
The Journal of biological chemistry 2023 Mar;299(3):102971
The Journal of biological chemistry 2023 Mar;299(3):102971
LOXL2 reduces 5-FU sensitivity through the Hedgehog/BCL2 signaling pathway in colorectal cancer.
Qiu Z, Qiu S, Mao W, Lin W, Peng Q, Chang H
Experimental biology and medicine (Maywood, N.J.) 2023 Mar;248(6):457-468
Experimental biology and medicine (Maywood, N.J.) 2023 Mar;248(6):457-468
N-homocysteinylation of α-synuclein promotes its aggregation and neurotoxicity.
Zhou L, Guo T, Meng L, Zhang X, Tian Y, Dai L, Niu X, Li Y, Liu C, Chen G, Liu C, Ke W, Zhang Z, Bao A, Zhang Z
Aging cell 2023 Mar;22(3):e13745
Aging cell 2023 Mar;22(3):e13745
Relationship Between Expression of microRNA and Chemotherapy Resistance in Cervical Carcinoma.
Chao-Hui H, Jing L, Xue C, Ting-Shi W, Chong L
Applied biochemistry and biotechnology 2023 Mar;195(3):1928-1946
Applied biochemistry and biotechnology 2023 Mar;195(3):1928-1946
P2X7 receptor involved in antitumor activity of atractylenolide I in human cervical cancer cells.
Han Y, Bai C, He XM, Ren QL
Purinergic signalling 2023 Mar;19(1):145-153
Purinergic signalling 2023 Mar;19(1):145-153
DTX3L induced NLRP3 ubiquitination inhibit R28 cell pyroptosis in OGD/R injury.
Zhou Z, Shang L, Zhang Q, Hu X, Huang JF, Xiong K
Biochimica et biophysica acta. Molecular cell research 2023 Mar;1870(3):119433
Biochimica et biophysica acta. Molecular cell research 2023 Mar;1870(3):119433
Ectopic endometriotic stromal cells-derived lactate induces M2 macrophage polarization via Mettl3/Trib1/ERK/STAT3 signalling pathway in endometriosis.
Gou Y, Wang H, Wang T, Wang H, Wang B, Jiao N, Yu Y, Cao Y, Wang H, Zhang Z
Immunology 2023 Mar;168(3):389-402
Immunology 2023 Mar;168(3):389-402
MicroRNA-183-5p regulates TAR DNA-binding protein 43 neurotoxicity via SQSTM1/p62 in amyotrophic lateral sclerosis.
Kim HC, Zhang Y, King PH, Lu L
Journal of neurochemistry 2023 Mar;164(5):643-657
Journal of neurochemistry 2023 Mar;164(5):643-657
Vasoactive intestinal peptide receptor 2 signaling promotes breast cancer cell proliferation by enhancing the ERK pathway.
Asano S, Ono A, Sakamoto K, Hayata-Takano A, Nakazawa T, Tanimoto K, Hashimoto H, Ago Y
Peptides 2023 Mar;161:170940
Peptides 2023 Mar;161:170940
Fructooligosaccharides attenuate non-alcoholic fatty liver disease by remodeling gut microbiota and association with lipid metabolism.
Huang X, Chen Q, Fan Y, Yang R, Gong G, Yan C, Song Y, Zhang B, Xi S, Huang Y, Xu H
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Mar;159:114300
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Mar;159:114300
Identification and characterization of a first-generation inhibitor of claudin-1 in colon cancer progression and metastasis.
Fatima I, Uppada JP, Chhonker YS, Gowrikumar S, Barman S, Roy S, Tolentino KT, Palermo N, Natarajan A, Beauchamp DR, Vecchio A, Murry DJ, Singh AB, Hopkins CR, Dhawan P
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Mar;159:114255
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Mar;159:114255
Antiangiogenic potential of Lepista nuda extract suppressing MAPK/p38 signaling-mediated developmental angiogenesis in zebrafish and HUVECs.
Deshmukh D, Hsu YF, Chiu CC, Jadhao M, Hsu SCN, Hu SY, Yang SH, Liu W
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Mar;159:114219
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Mar;159:114219
Ganoapplins A and B with an unprecedented 6/6/6/5/6-fused pentacyclic skeleton from Ganoderma inhibit Tau pathology through activating autophagy.
Peng X, Luo R, Ran X, Guo Y, Yao YG, Qiu M
Bioorganic chemistry 2023 Mar;132:106375
Bioorganic chemistry 2023 Mar;132:106375
Onychiol B attenuates lipopolysaccharide-induced inflammation via MAPK/NF-κB pathways and acute lung injury in vivo.
Pei X, Zhang Z, Wang N, Huang G, Min X, Yang Y, Cao J
Bioorganic chemistry 2023 Mar;132:106351
Bioorganic chemistry 2023 Mar;132:106351
LncRNA SPRY4-IT1 facilitates cell proliferation and angiogenesis of glioma via the miR-101-3p/EZH2/VEGFA signaling axis.
Wang J, Chen Y, Wang Q, Xu H, Jiang Q, Wang M, Li S, Chen Y, Wu C, Yu P, Xiao Z, Chen W, Lan Q
Cancer medicine 2023 Mar;12(6):7309-7326
Cancer medicine 2023 Mar;12(6):7309-7326
Cyclin-dependent kinase subunit2 (CKS2) promotes malignant phenotypes and epithelial-mesenchymal transition-like process in glioma by activating TGFβ/SMAD signaling.
Feng F, Zhao Z, Cai X, Heng X, Ma X
Cancer medicine 2023 Mar;12(5):5889-5907
Cancer medicine 2023 Mar;12(5):5889-5907
MARCO is a potential prognostic and immunotherapy biomarker.
Dong Q, Zhang S, Zhang H, Sun J, Lu J, Wang G, Wang X
International immunopharmacology 2023 Mar;116:109783
International immunopharmacology 2023 Mar;116:109783
ProBDNF signaling is involved in periodontitis-induced depression-like behavior in mouse hippocampus.
Li Y, Guan X, He Y, Jia X, Pan L, Wang Y, Han Y, Zhao R, Yang J, Hou T
International immunopharmacology 2023 Mar;116:109767
International immunopharmacology 2023 Mar;116:109767
UVA1 irradiation attenuates collagen production via Ficz/AhR/MAPK signaling activation in scleroderma.
Shi Y, Xiao Y, Yu J, Liu J, Liu L, Ding Y, Qiu X, Zhan Y, Tang R, Zeng Z, Xiao R
International immunopharmacology 2023 Mar;116:109764
International immunopharmacology 2023 Mar;116:109764
FGF4 improves hepatocytes ferroptosis in autoimmune hepatitis mice via activation of CISD3.
Jiang H, Fang Y, Wang Y, Li T, Lin H, Lin J, Pan T, Liu Q, Lv J, Chen D, Chen Y
International immunopharmacology 2023 Mar;116:109762
International immunopharmacology 2023 Mar;116:109762
Identification of fatty acid metabolism-based molecular subtypes and prognostic signature to predict immune landscape and guide clinical drug treatment in renal clear cell carcinoma.
Wang L, Shen J, Wang Y, Bi J
International immunopharmacology 2023 Mar;116:109735
International immunopharmacology 2023 Mar;116:109735
pNaktide mitigates inflammation-induced neuronal damage and behavioral deficits through the oxidative stress pathway.
Zong Q, Pan Y, Liu Y, Wu Z, Huang Z, Zhang Y, Ma K
International immunopharmacology 2023 Mar;116:109727
International immunopharmacology 2023 Mar;116:109727
Wumei Wan attenuates angiogenesis and inflammation by modulating RAGE signaling pathway in IBD: Network pharmacology analysis and experimental evidence.
Duan ZL, Wang YJ, Lu ZH, Tian L, Xia ZQ, Wang KL, Chen T, Wang R, Feng ZY, Shi GP, Xu XT, Bu F, Ding Y, Jiang F, Zhou JY, Wang Q, Chen YG
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Mar;111:154658
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Mar;111:154658
Cimifugin suppresses type 2 airway inflammation by binding to SPR and regulating its protein expression in a non-enzymatic manner.
Gu X, Chen Y, Qian P, He T, Wu Y, Lin W, Zheng J, Hong M
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Mar;111:154657
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Mar;111:154657
SIRT6 attenuates LPS-induced inflammation and apoptosis of lung epithelial cells in acute lung injury through ACE2/STAT3/PIM1 signaling.
Yang J, Chen X
Immunity, inflammation and disease 2023 Mar;11(3):e809
Immunity, inflammation and disease 2023 Mar;11(3):e809
Subacute ruminal acidosis downregulates FOXA2, changes oxidative status, and induces autophagy in the livers of dairy cows fed a high-concentrate diet.
Zhang H, Xue Y, Xie W, Wang Y, Ma N, Chang G, Shen X
Journal of dairy science 2023 Mar;106(3):2007-2018
Journal of dairy science 2023 Mar;106(3):2007-2018
ArfGAP3 regulates vesicle transport and glucose uptake in myoblasts.
Li S, Wang Z, Chen M, Xiao Y, Min J, Hu M, Tang J, Hong L
Cellular signalling 2023 Mar;103:110551
Cellular signalling 2023 Mar;103:110551
N6-methyladenosine modified LINC00901 promotes pancreatic cancer progression through IGF2BP2/MYC axis.
Peng WX, Liu F, Jiang JH, Yuan H, Zhang Z, Yang L, Mo YY
Genes & diseases 2023 Mar;10(2):554-567
Genes & diseases 2023 Mar;10(2):554-567
SKA1 is overexpressed in laryngocarcinoma and modulates cell growth via P53 signaling pathway.
Li Z, Liu J, Peng H, Li C, Liu Y, Xie W
Cell cycle (Georgetown, Tex.) 2023 Mar-Mar;22(6):693-704
Cell cycle (Georgetown, Tex.) 2023 Mar-Mar;22(6):693-704
Oncogenes and Methionine Addiction of Cancer: Role of c-MYC.
Aoki Y, Han Q, Kubota Y, Masaki N, Obara K, Tome Y, Bouvet M, Nishida K, Hoffman RM
Cancer genomics & proteomics 2023 Mar-Apr;20(2):165-170
Cancer genomics & proteomics 2023 Mar-Apr;20(2):165-170
A Comprehensive Analysis Revealing FBXW9 as a Potential Prognostic and Immunological Biomarker in Breast Cancer.
Yu S, Liang Z, Fan Z, Cao B, Wang N, Wu R, Sun H
International journal of molecular sciences 2023 Mar 9;24(6)
International journal of molecular sciences 2023 Mar 9;24(6)
Naringenin Attenuates Isoprenaline-Induced Cardiac Hypertrophy by Suppressing Oxidative Stress through the AMPK/NOX2/MAPK Signaling Pathway.
Li Y, He B, Zhang C, He Y, Xia T, Zeng C
Nutrients 2023 Mar 9;15(6)
Nutrients 2023 Mar 9;15(6)
PVT1 inhibition stimulates anti-tumor immunity, prevents metastasis, and depletes cancer stem cells in squamous cell carcinoma.
Qin Z, Zhang W, Liu S, Wang Y, Peng X, Jia L
Cell death & disease 2023 Mar 9;14(3):187
Cell death & disease 2023 Mar 9;14(3):187
Ophiobolin A Covalently Targets Complex IV Leading to Mitochondrial Metabolic Collapse in Cancer Cells.
Gowans FA, Thach DQ, Wang Y, Altamirano Poblano BE, Dovala D, Tallarico JA, McKenna JM, Schirle M, Maimone TJ, Nomura DK
bioRxiv : the preprint server for biology 2023 Mar 9;
bioRxiv : the preprint server for biology 2023 Mar 9;
Aspergillus fumigatus hijacks human p11 to redirect fungal-containing phagosomes to non-degradative pathway.
Jia LJ, Rafiq M, Radosa L, Hortschansky P, Cunha C, Cseresnyés Z, Krüger T, Schmidt F, Heinekamp T, Straßburger M, Löffler B, Doenst T, Lacerda JF, Campos A Jr, Figge MT, Carvalho A, Kniemeyer O, Brakhage AA
Cell host & microbe 2023 Mar 8;31(3):373-388.e10
Cell host & microbe 2023 Mar 8;31(3):373-388.e10
Maternal Immune Activation Induces Adolescent Cognitive Deficits Preceded by Developmental Perturbations in Cortical Reelin Signalling.
Woods RM, Lorusso JM, Harris I, Kowash HM, Murgatroyd C, Neill JC, Glazier JD, Harte M, Hager R
Biomolecules 2023 Mar 7;13(3)
Biomolecules 2023 Mar 7;13(3)
Macrophage-derived exosomes mediate glomerular endothelial cell dysfunction in sepsis-associated acute kidney injury.
Xiang H, Xu Z, Zhang C, Xiong J
Cell & bioscience 2023 Mar 7;13(1):46
Cell & bioscience 2023 Mar 7;13(1):46
ROS-dependent palmitoylation is an obligate licensing modification for GSDMD pore formation.
Du G, Healy LB, David L, Walker C, Fontana P, Dong Y, Devant P, Puthenveetil R, Ficarro SB, Banerjee A, Kagan JC, Lieberman J, Wu H
bioRxiv : the preprint server for biology 2023 Mar 7;
bioRxiv : the preprint server for biology 2023 Mar 7;
Mitoguardin2 Is Associated With Hyperandrogenism and Regulates Steroidogenesis in Human Ovarian Granulosa Cells.
Yan MQ, Wang Y, Wang Z, Liu XH, Yang YM, Duan XY, Sun H, Liu XM
Journal of the Endocrine Society 2023 Mar 6;7(5):bvad034
Journal of the Endocrine Society 2023 Mar 6;7(5):bvad034
A nucleotide binding-independent role for γ-tubulin in microtubule capping and cell division.
Berman AY, Wieczorek M, Aher A, Olinares PDB, Chait BT, Kapoor TM
The Journal of cell biology 2023 Mar 6;222(3)
The Journal of cell biology 2023 Mar 6;222(3)
Repurposing a tricyclic antidepressant in tumor and metabolism disease treatment through fatty acid uptake inhibition.
Chu Q, An J, Liu P, Song Y, Zhai X, Yang R, Niu J, Yang C, Li B
The Journal of experimental medicine 2023 Mar 6;220(3)
The Journal of experimental medicine 2023 Mar 6;220(3)
PABPN1 regulates mRNA alternative polyadenylation to inhibit bladder cancer progression.
Chen L, Dong W, Zhou M, Yang C, Xiong M, Kazobinka G, Chen Z, Xing Y, Hou T
Cell & bioscience 2023 Mar 6;13(1):45
Cell & bioscience 2023 Mar 6;13(1):45
BMAL1 Promotes Valvular Interstitial Cells' Osteogenic Differentiation through NF-κ B/AKT/MAPK Pathway.
Jiang Y, Wang S, Lin W, Gu J, Li G, Shao Y
Journal of cardiovascular development and disease 2023 Mar 6;10(3)
Journal of cardiovascular development and disease 2023 Mar 6;10(3)
Sertaconazole nitrate targets IDO1 and regulates the MAPK signaling pathway to induce autophagy and apoptosis in CRC cells.
Yang Y, Jin Y, Yin L, Liu P, Zhu L, Gao H
European journal of pharmacology 2023 Mar 5;942:175515
European journal of pharmacology 2023 Mar 5;942:175515
A peptide encoded by lncRNA MIR7-3 host gene (MIR7-3HG) alleviates dexamethasone-induced dysfunction in pancreatic β-cells through the PI3K/AKT signaling pathway.
Mao X, Zhou J, Kong L, Zhu L, Yang D, Zhang Z
Biochemical and biophysical research communications 2023 Mar 5;647:62-71
Biochemical and biophysical research communications 2023 Mar 5;647:62-71
Discovery of novel and bioavailable histone deacetylases and cyclin-dependent kinases dual inhibitor to impair the stemness of leukemia cells.
Liu Y, Wei Y, Wang X, Ma L, Li X, Sun Y, Wu Y, Zhang L, Wang J, Li M, Zhang K, Wei M, Yang G, Yang C
European journal of medicinal chemistry 2023 Mar 5;249:115140
European journal of medicinal chemistry 2023 Mar 5;249:115140
The Wnt/β-catenin pathway regulates inflammation and apoptosis in ventilator-induced lung injury.
Chen Z, He S, Lian S, Shen Y, Jiang W, Zhou L, Zhou L, Zhang X
Bioscience reports 2023 Mar 31;43(3)
Bioscience reports 2023 Mar 31;43(3)
Cadherin-11-Interleukin-6 Signaling between Cardiac Fibroblast and Cardiomyocyte Promotes Ventricular Remodeling in a Mouse Pressure Overload-Induced Heart Failure Model.
Fang G, Li Y, Yuan J, Cao W, Song S, Chen L, Wang Y, Wang Q
International journal of molecular sciences 2023 Mar 31;24(7)
International journal of molecular sciences 2023 Mar 31;24(7)
ARNTL2 upregulation of ACOT7 promotes NSCLC cell proliferation through inhibition of apoptosis and ferroptosis.
Wang T, Wang K, Zhu X, Chen N
BMC molecular and cell biology 2023 Mar 31;24(1):14
BMC molecular and cell biology 2023 Mar 31;24(1):14
DNAJB7 is dispensable for male fertility in mice.
Bai S, Hu M, Yu L, Chen L, Zhou J, Wu L, Xu B, Jiang X, Zhang X, Tong X, Yue Q
Reproductive biology and endocrinology : RB&E 2023 Mar 31;21(1):32
Reproductive biology and endocrinology : RB&E 2023 Mar 31;21(1):32
Endothelial deletion of PTBP1 disrupts ventricular chamber development.
Liu H, Duan R, He X, Qi J, Xing T, Wu Y, Zhou L, Wang L, Shao Y, Zhang F, Zhou H, Gu X, Lin B, Liu Y, Wang Y, Liu Y, Li L, Liang D, Chen YH
Nature communications 2023 Mar 31;14(1):1796
Nature communications 2023 Mar 31;14(1):1796
Integrated Proteomics Unveils Nuclear PDE3A2 as a Regulator of Cardiac Myocyte Hypertrophy.
Subramaniam G, Schleicher K, Kovanich D, Zerio A, Folkmanaite M, Chao YC, Surdo NC, Koschinski A, Hu J, Scholten A, Heck AJR, Ercu M, Sholokh A, Park KC, Klussmann E, Meraviglia V, Bellin M, Zanivan S, Hester S, Mohammed S, Zaccolo M
Circulation research 2023 Mar 31;132(7):828-848
Circulation research 2023 Mar 31;132(7):828-848
Pseudorabies Virus Infection Activates the TLR-NF-κB Axis and AIM2 Inflammasome To Enhance Inflammatory Responses in Mice.
Zhou Q, Zhang L, Lin Q, Liu H, Ye G, Liu X, Jiao S, Li J, Tang Y, Shi D, Huang L, Weng C
Journal of virology 2023 Mar 30;97(3):e0000323
Journal of virology 2023 Mar 30;97(3):e0000323
A thalamic-primary auditory cortex circuit mediates resilience to stress.
Li HY, Zhu MZ, Yuan XR, Guo ZX, Pan YD, Li YQ, Zhu XH
Cell 2023 Mar 30;186(7):1352-1368.e18
Cell 2023 Mar 30;186(7):1352-1368.e18
SODD Promotes Lung Cancer Tumorigenesis by Activating the PDK1/AKT and RAF/MEK/ERK Signaling.
Bao F, An S, Yang Y, Xu TR
Genes 2023 Mar 30;14(4)
Genes 2023 Mar 30;14(4)
CREB3L2-ATF4 heterodimerization defines a transcriptional hub of Alzheimer's disease gene expression linked to neuropathology.
Gouveia Roque C, Chung KM, McCurdy EP, Jagannathan R, Randolph LK, Herline-Killian K, Baleriola J, Hengst U
Science advances 2023 Mar 3;9(9):eadd2671
Science advances 2023 Mar 3;9(9):eadd2671
CPT1A modulates PI3K/Akt/mTOR pathway to promote preeclampsia.
Chen M, Chao B, Xu J, Liu Z, Tao Y, He J, Wang J, Yang H, Luo X, Qi H
Placenta 2023 Mar 3;133:23-31
Placenta 2023 Mar 3;133:23-31
FBXW7 loss of function promotes esophageal squamous cell carcinoma progression via elevating MAP4 and ERK phosphorylation.
Pan Y, Liu J, Gao Y, Guo Y, Wang C, Liang Z, Wu M, Qian Y, Li Y, Shen J, Lu C, Ma S
Journal of experimental & clinical cancer research : CR 2023 Mar 29;42(1):75
Journal of experimental & clinical cancer research : CR 2023 Mar 29;42(1):75
Tubeimoside-2 Triggers Methuosis in Hepatocarcinoma Cells through the MKK4-p38α Axis.
Gan Y, Wang C, Chen Y, Hua L, Fang H, Li S, Chai S, Xu Y, Zhang J, Gu Y
Pharmaceutics 2023 Mar 29;15(4)
Pharmaceutics 2023 Mar 29;15(4)
Comprehensive proteogenomic characterization of early duodenal cancer reveals the carcinogenesis tracks of different subtypes.
Li L, Jiang D, Liu H, Guo C, Zhao R, Zhang Q, Xu C, Qin Z, Feng J, Liu Y, Wang H, Chen W, Zhang X, Li B, Bai L, Tian S, Tan S, Yu Z, Chen L, Huang J, Zhao JY, Hou Y, Ding C
Nature communications 2023 Mar 29;14(1):1751
Nature communications 2023 Mar 29;14(1):1751
Disturbed rhythmicity of intestinal hydrogen peroxide alters gut microbial oscillations in BMAL1-deficient monkeys.
Yang Y, Yu P, Lu Y, Gao C, Sun Q
Cell reports 2023 Mar 28;42(3):112183
Cell reports 2023 Mar 28;42(3):112183
METTL16 promotes translation and lung tumorigenesis by sequestering cytoplasmic eIF4E2.
Wang F, Zhang J, Lin X, Yang L, Zhou Q, Mi X, Li Q, Wang S, Li D, Liu XM, Zhou J
Cell reports 2023 Mar 28;42(3):112150
Cell reports 2023 Mar 28;42(3):112150
Development of FRET and Stress Granule Dual-Based System to Screen for Viral 3C Protease Inhibitors.
Zhang J, Jiang Y, Wu C, Zhou D, Gong J, Zhao T, Jin Z
Molecules (Basel, Switzerland) 2023 Mar 28;28(7)
Molecules (Basel, Switzerland) 2023 Mar 28;28(7)
Voluntary Exercise to Reduce Anxiety Behaviour in Traumatic Brain Injury Shown to Alleviate Inflammatory Brain Response in Mice.
Hu X, Ou Y, Li J, Sun M, Ge Q, Pan Y, Cai Z, Tan R, Wang W, An J, Lu H
International journal of molecular sciences 2023 Mar 28;24(7)
International journal of molecular sciences 2023 Mar 28;24(7)
Muscle PARP1 inhibition extends lifespan through AMPKα PARylation and activation in Drosophila.
Guo S, Zhang S, Zhuang Y, Xie F, Wang R, Kong X, Zhang Q, Feng Y, Gao H, Kong X, Liu T
Proceedings of the National Academy of Sciences of the United States of America 2023 Mar 28;120(13):e2213857120
Proceedings of the National Academy of Sciences of the United States of America 2023 Mar 28;120(13):e2213857120
Integration of metabolomics and transcriptomics to reveal ferroptosis is involved in Tripterygium wilfordii polyglycoside tablet-induced testicular injury.
Qin Z, Zhang G, Jiang S, Ning F, Zhao Z, Huang M, Jin J
Journal of ethnopharmacology 2023 Mar 25;304:116055
Journal of ethnopharmacology 2023 Mar 25;304:116055
Erxian decoction alleviates cisplatin-induced premature ovarian failure in rats by reducing oxidation levels in ovarian granulosa cells.
Liu J, Yang Y, He Y, Feng C, Ou H, Yang J, Chen Y, You F, Shao B, Bao J, Guan X, Chen F, Zhao P
Journal of ethnopharmacology 2023 Mar 25;304:116046
Journal of ethnopharmacology 2023 Mar 25;304:116046
Mutation at the Site of Hydroxylation in the Ribosomal Protein uL15 (RPL27a) Causes Specific Changes in the Repertoire of mRNAs Translated in Mammalian Cells.
Zolotenkova EA, Gopanenko AV, Tupikin AE, Kabilov MR, Malygin AA
International journal of molecular sciences 2023 Mar 24;24(7)
International journal of molecular sciences 2023 Mar 24;24(7)
Inhibition of miR-4640-5p alleviates pulmonary hypertension in chronic obstructive pulmonary disease patients by regulating nitric oxide synthase 1.
Yang Z, Li P, Yuan Q, Wang X, Ma HH, Zhuan B
Respiratory research 2023 Mar 24;24(1):92
Respiratory research 2023 Mar 24;24(1):92
CCNE1 is a predictive and immunotherapeutic indicator in various cancers including UCEC: a pan-cancer analysis.
Zheng X, Chen L, Liu W, Zhao S, Yan Y, Zhao J, Tian W, Wang Y
Hereditas 2023 Mar 24;160(1):13
Hereditas 2023 Mar 24;160(1):13
The OTUD1-Notch2-ICD axis orchestrates allogeneic T cell-mediated graft-versus-host disease.
Cheng Q, Wang D, Lai X, Liu Y, Zuo Y, Zhang W, Lei L, Chen J, Liu H, Wang Y, Liu H, Zheng H, Wu D, Xu Y
Blood 2023 Mar 23;141(12):1474-1488
Blood 2023 Mar 23;141(12):1474-1488
Pan-cancer analysis of PCAT6 and its effect on oesophageal squamous cell carcinoma cell proliferation and migration.
Luo Q, Kuang Y, Tao X, Zhu X, Zhao X, Lu G, Zhang W, Sun E, Chen B
Medical oncology (Northwood, London, England) 2023 Mar 22;40(4):125
Medical oncology (Northwood, London, England) 2023 Mar 22;40(4):125
The short isoform of MS4A7 is a novel player in glioblastoma microenvironment, M2 macrophage polarization, and tumor progression.
Ni B, Huang G, Yang R, Wang Z, Song H, Li K, Zhang Y, Wu K, Shi G, Wang X, Shen J, Liu Y
Journal of neuroinflammation 2023 Mar 21;20(1):80
Journal of neuroinflammation 2023 Mar 21;20(1):80
The Slingshot phosphatase 2 is required for acrosome biogenesis during spermatogenesis in mice.
Xu K, Su X, Fang K, Lv Y, Huang T, Li M, Wang Z, Yin Y, Muhammad T, Liu S, Chen X, Jiang J, Li J, Chan WY, Ma J, Lu G, Chen ZJ, Liu H
eLife 2023 Mar 21;12
eLife 2023 Mar 21;12
LIFR recruits HGF-producing neutrophils to promote liver injury repair and regeneration.
Deng Y, Zhao Z, Sheldon M, Zhao Y, Teng H, Martinez C, Zhang J, Lin C, Sun Y, Yao F, Zhu H, Ma L
bioRxiv : the preprint server for biology 2023 Mar 21;
bioRxiv : the preprint server for biology 2023 Mar 21;
Protocol for the identification and expression analysis of a cytoplasmic membrane-localized protein STING.
Shi J, Liu C, Luo S, Zhang Y, Li M, Zhou M, Weng M, Li X, Zheng T
STAR protocols 2023 Mar 20;4(2):102172
STAR protocols 2023 Mar 20;4(2):102172
TUBA1C: a new potential target of LncRNA EGFR-AS1 promotes gastric cancer progression.
Wang H, Cui H, Yang X, Peng L
BMC cancer 2023 Mar 20;23(1):258
BMC cancer 2023 Mar 20;23(1):258
Overexpression of YEATS2 Remodels the Extracellular Matrix to Promote Hepatocellular Carcinoma Progression via the PI3K/AKT Pathway.
Liu X, Hu Y, Li C, Chen J, Liu X, Shen Y, Xu Y, Chen W, Xu X
Cancers 2023 Mar 20;15(6)
Cancers 2023 Mar 20;15(6)
Effects of Spatial Expression of Activating Transcription Factor 4 on the Pathogenicity of Two Phenotypes of Bovine Viral Diarrhea Virus by Regulating the Endoplasmic Reticulum-Mediated Autophagy Process.
Wang J, Chen KY, Wang SH, Liu Y, Zhao YQ, Yang L, Yang GH, Wang XJ, Zhu YH, Yin JH, Wang JF
Microbiology spectrum 2023 Mar 20;11(2):e0422522
Microbiology spectrum 2023 Mar 20;11(2):e0422522
Bone Marrow Mesenchymal Stem Cells-Derived miR-21-5p Protects Grafted Islets Against Apoptosis by Targeting PDCD4.
Wang J, Wang J, Wang Y, Ma R, Zhang S, Zheng J, Xue W, Ding X
Stem cells (Dayton, Ohio) 2023 Mar 2;41(2):169-183
Stem cells (Dayton, Ohio) 2023 Mar 2;41(2):169-183
Cuproptosis-Related Gene DLAT as a Novel Biomarker Correlated with Prognosis, Chemoresistance, and Immune Infiltration in Pancreatic Adenocarcinoma: A Preliminary Study Based on Bioinformatics Analysis.
Fang Z, Wang W, Liu Y, Hua J, Liang C, Liu J, Zhang B, Shi S, Yu X, Meng Q, Xu J
Current oncology (Toronto, Ont.) 2023 Mar 2;30(3):2997-3019
Current oncology (Toronto, Ont.) 2023 Mar 2;30(3):2997-3019
Valproic acid inhibits cell growth in both MCF-7 and MDA-MB231 cells by triggering different responses in a cell type-specific manner.
Giordano F, Paolì A, Forastiero M, Marsico S, De Amicis F, Marrelli M, Naimo GD, Mauro L, Panno ML
Journal of translational medicine 2023 Mar 2;21(1):165
Journal of translational medicine 2023 Mar 2;21(1):165
Vacuolar protein sorting 35 (VPS35) acts as a tumor promoter via facilitating cell cycle progression in pancreatic ductal adenocarcinoma.
Gai Y, Qian L, Jiang S, Li J, Zhang X, Yang X, Pan H, Liao Y, Wang H, Huang S, Zhang S, Nie H, Ma M, Li H
Functional & integrative genomics 2023 Mar 18;23(2):90
Functional & integrative genomics 2023 Mar 18;23(2):90
The structural flexibility of MAD1 facilitates the assembly of the Mitotic Checkpoint Complex.
Chen C, Piano V, Alex A, Han SJY, Huis In 't Veld PJ, Roy B, Fergle D, Musacchio A, Joglekar AP
Nature communications 2023 Mar 18;14(1):1529
Nature communications 2023 Mar 18;14(1):1529
Acute liver steatosis translationally controls the epigenetic regulator MIER1 to promote liver regeneration in a study with male mice.
Chen Y, Chen L, Wu X, Zhao Y, Wang Y, Jiang D, Liu X, Zhou T, Li S, Wei Y, Liu Y, Hu C, Zhou B, Qin J, Ying H, Ding Q
Nature communications 2023 Mar 18;14(1):1521
Nature communications 2023 Mar 18;14(1):1521
Inducing primary brainstem gliomas in genetically engineered mice using RCAS/TVA retroviruses and Cre/loxP recombination.
Weidenhammer LB, Liu HQ, Luo L, Williams NT, Deland K, Kirsch DG, Reitman ZJ
STAR protocols 2023 Mar 17;4(1):102094
STAR protocols 2023 Mar 17;4(1):102094
PPT1 regulation of HSP90α depalmitoylation participates in the pathogenesis of hyperandrogenism.
Xue T, Zhao S, Zhang H, Tang T, Zheng L, Jing J, Ge X, Ma R, Ma J, Ren X, Jueraitetibaike K, Guo Z, Chen L, Yao B
iScience 2023 Mar 17;26(3):106131
iScience 2023 Mar 17;26(3):106131
Elucidation of OSW-1-Induced Stress Responses in Neuro2a Cells.
Oh-Hashi K, Nakamura H, Ogawa H, Hirata Y, Sakurai K
International journal of molecular sciences 2023 Mar 17;24(6)
International journal of molecular sciences 2023 Mar 17;24(6)
Nutrient deprivation alters the rate of COPII coat assembly to tune secretory protein transport.
Kasberg W, Luong P, Swift KA, Audhya A
Research square 2023 Mar 17;
Research square 2023 Mar 17;
Reduced SUMOylation of Nrf2 signaling contributes to its inhibition induced by amyloid-β.
Wang P, Wang X, Qiao K, Zhang Y, Nie Q, Cui J, Sun J, Li L
Neuroscience letters 2023 Mar 16;799:137118
Neuroscience letters 2023 Mar 16;799:137118
High Expression of COA6 Is Related to Unfavorable Prognosis and Enhanced Oxidative Phosphorylation in Lung Adenocarcinoma.
Zhang M, Liao X, Ji G, Fan X, Wu Q
International journal of molecular sciences 2023 Mar 16;24(6)
International journal of molecular sciences 2023 Mar 16;24(6)
PRAME Promotes Cervical Cancer Proliferation and Migration via Wnt/β-Catenin Pathway Regulation.
Chen X, Jiang M, Zhou S, Chen H, Song G, Wu Y, Zhu X
Cancers 2023 Mar 16;15(6)
Cancers 2023 Mar 16;15(6)
Intraduodenal Delivery of Exosome-Loaded SARS-CoV-2 RBD mRNA Induces a Neutralizing Antibody Response in Mice.
Zhang Q, Wang M, Han C, Wen Z, Meng X, Qi D, Wang N, Du H, Wang J, Lu L, Ge X
Vaccines 2023 Mar 16;11(3)
Vaccines 2023 Mar 16;11(3)
Curcumol suppresses endothelial-to-mesenchymal transition via inhibiting the AKT/GSK3β signaling pathway and alleviates pulmonary arterial hypertension in rats.
Nie X, Wu Z, Shang J, Zhu L, Liu Y, Qi Y
European journal of pharmacology 2023 Mar 15;943:175546
European journal of pharmacology 2023 Mar 15;943:175546
Identification of a novel missense SCN5A mutation in a Chinese Han family with Brugada syndrome.
Zhu J, Shen Y, Xiong H, Zha H, Zhang L, Peng H, Tian L
Biochemical and biophysical research communications 2023 Mar 15;649:55-61
Biochemical and biophysical research communications 2023 Mar 15;649:55-61
Increased Cellular Expression of Interleukin-6 in Patients With Ossification of the Posterior Longitudinal Ligament.
Saito H, Yayama T, Mori K, Kumagai K, Fujikawa H, Chosei Y, Imai S
Spine 2023 Mar 15;48(6):E78-E86
Spine 2023 Mar 15;48(6):E78-E86
HMGB1 coordinates with Brahma-related gene 1 to promote epithelial-mesenchymal transition via the PI3K/Akt/mTOR pathway in BEAS-2B cells.
Deng X, Niu Z, Hao C, Lin J, Yao W
Experimental cell research 2023 Mar 15;424(2):113522
Experimental cell research 2023 Mar 15;424(2):113522
Environmentally relevant perinatal exposure to DBP accelerated spermatogenesis by promoting the glycolipid metabolism of Sertoli cells in male offspring mice.
Ma T, Xia Y, Wang B, Yang F, Ding J, Wu J, Han X, Wang J, Li D
Toxicology letters 2023 Mar 15;377:16-28
Toxicology letters 2023 Mar 15;377:16-28
TFE3-mediated impairment of lysosomal biogenesis and defective autophagy contribute to fluoride-induced hepatotoxicity.
Hu Z, Xu W, Zhang J, Tang Y, Xing H, Xu P, Ma Y, Niu Q
Ecotoxicology and environmental safety 2023 Mar 15;253:114674
Ecotoxicology and environmental safety 2023 Mar 15;253:114674
Discovery of unglycosylated indolocarbazoles as ROCK2 isoform-selective inhibitors for the treatment of breast cancer metastasis.
Wang J, Gao T, Ma Y, Zhang Y, Yi Y, Yan F, Cheng Z, Yu Y, Li J, Chen Z, Ding W, Ma Z
European journal of medicinal chemistry 2023 Mar 15;250:115181
European journal of medicinal chemistry 2023 Mar 15;250:115181
RIG-I Promotes Tumorigenesis and Confers Radioresistance of Esophageal Squamous Cell Carcinoma by Regulating DUSP6.
Li L, Lv L, Xu JC, He Q, Chang N, Cui YY, Tao ZC, Zhu T, Qian LT
International journal of molecular sciences 2023 Mar 15;24(6)
International journal of molecular sciences 2023 Mar 15;24(6)
Shared Genes of PPARG and NOS2 in Alzheimer's Disease and Ulcerative Colitis Drive Macrophages and Microglia Polarization: Evidence from Bioinformatics Analysis and Following Validation.
Dong L, Shen Y, Li H, Zhang R, Yu S, Wu Q
International journal of molecular sciences 2023 Mar 15;24(6)
International journal of molecular sciences 2023 Mar 15;24(6)
Characterization of RNA G-quadruplexes in porcine epidemic diarrhea virus genome and the antiviral activity of G-quadruplex ligands.
Li Y, Zhu Y, Wang Y, Feng Y, Li D, Li S, Qin P, Yang X, Chen L, Zhao J, Zhang C, Li Y
International journal of biological macromolecules 2023 Mar 15;231:123282
International journal of biological macromolecules 2023 Mar 15;231:123282
A novel gene therapy for methamphetamine- induced cognitive disorder with a hyper-acidified fusion variant of DnaJB1.
Zhang M, Chen C, Peng Q, Wu X, Zhou R, Ma Y, Zou Z
Molecular therapy. Nucleic acids 2023 Mar 14;31:703-716
Molecular therapy. Nucleic acids 2023 Mar 14;31:703-716
Apigenin reduces the suppressive effect of exosomes derived from irritable bowel syndrome patients on the autophagy of human colon epithelial cells by promoting ATG14.
Fu R, Liu S, Zhu M, Zhu J, Chen M
World journal of surgical oncology 2023 Mar 14;21(1):95
World journal of surgical oncology 2023 Mar 14;21(1):95
Autophagy Function and Benefits of Autophagy Induction in Models of Spinocerebellar Ataxia Type 3.
Watchon M, Luu L, Plenderleith SK, Yuan KC, Laird AS
Cells 2023 Mar 14;12(6)
Cells 2023 Mar 14;12(6)
IFIT2 Depletion Promotes Cancer Stem Cell-like Phenotypes in Oral Cancer.
Lai KC, Regmi P, Liu CJ, Lo JF, Lee TC
Biomedicines 2023 Mar 14;11(3)
Biomedicines 2023 Mar 14;11(3)
Vascular Endothelial Growth Factor A Contributes to Increased Mammalian Respiratory Epithelial Permeability Induced by Pasteurella multocida Infection.
Lin L, Yang J, Zhang D, Lv Q, Wang F, Liu P, Wang M, Shi C, Huang X, Liang W, Tan C, Wang X, Chen H, Wilson BA, Wu B, Peng Z
Microbiology spectrum 2023 Mar 14;11(2):e0455422
Microbiology spectrum 2023 Mar 14;11(2):e0455422
PCGEM1 promotes cell proliferation and migration in endometriosis by targeting miR-124-3p-mediated ANTXR2 expression.
Liu Y, Xie C, Li T, Lu C, Fan L, Zhang Z, Peng S, Lv N, Lu D
BMC women's health 2023 Mar 13;23(1):104
BMC women's health 2023 Mar 13;23(1):104
Homeobox D9 drives the malignant phenotypes and enhances the Programmed death ligand-1 expression in non-small cell lung cancer cells via binding to Angiopoietin-2 promoter.
He J, Jiang M, Liu J, Zhu R, Lv W, Lian R, Yang Y, Wang R
World journal of surgical oncology 2023 Mar 13;21(1):93
World journal of surgical oncology 2023 Mar 13;21(1):93
The cellular and KSHV A-to-I RNA editome in primary effusion lymphoma and its role in the viral lifecycle.
Rajendren S, Ye X, Dunker W, Richardson A, Karijolich J
Nature communications 2023 Mar 13;14(1):1367
Nature communications 2023 Mar 13;14(1):1367
Maslinic Acid Supplementation during the In Vitro Culture Period Ameliorates Early Embryonic Development of Porcine Embryos by Regulating Oxidative Stress.
Yang TT, Qi JJ, Sun BX, Qu HX, Wei HK, Sun H, Jiang H, Zhang JB, Liang S
Animals : an open access journal from MDPI 2023 Mar 13;13(6)
Animals : an open access journal from MDPI 2023 Mar 13;13(6)
P53 Deficiency Accelerate Esophageal Epithelium Intestinal Metaplasia Malignancy.
Qiu Q, Guo G, Guo X, Hu X, Yu T, Liu G, Zhang H, Chen Y, She J
Biomedicines 2023 Mar 13;11(3)
Biomedicines 2023 Mar 13;11(3)
Hypoxia-Induced Kidney Injury in Newborn Rats.
Chu YT, Chen BH, Chen HH, Lee JC, Kuo TJ, Chiu HC, Lu WH
Toxics 2023 Mar 11;11(3)
Toxics 2023 Mar 11;11(3)
Stratification and therapeutic potential of ELL in cytogenetic normal acute myeloid leukemia.
Zha J, Zhong M, Pan G, Chen Q, Jiang Y, Lai Q, Tan J, Zhou H, Wu H, Xu B
Gene 2023 Mar 10;856:147110
Gene 2023 Mar 10;856:147110
ROS generation and p-38 activation contribute to montmorillonite-induced corneal toxicity in vitro and in vivo.
Liu J, Yang S, Zhao L, Jiang F, Sun J, Peng S, Zhao R, Huang Y, Fu X, Luo R, Jiang Y, Li Z, Wang N, Fang T, Zhang Z
Particle and fibre toxicology 2023 Mar 10;20(1):8
Particle and fibre toxicology 2023 Mar 10;20(1):8
Structure optimization and discovery of novel compound for the treatment of insertion mutations within exon 20 of EGFR and HER2.
Cui Y, Wang R, Wei Y, Hou F, Li H, Jiang Y, Sun Y, Fu S, Zuo L, Wang X, Li M, Li J, Liu N, Zhang K, Wei M, Yang G
Bioorganic & medicinal chemistry 2023 Mar 1;81:117202
Bioorganic & medicinal chemistry 2023 Mar 1;81:117202
Time-Course Transcriptomic Analysis Reveals the Crucial Roles of PANoptosis in Fungal Keratitis.
Xu X, Wei Y, Pang J, Wei Z, Wang L, Chen Q, Wang Z, Zhang Y, Chen K, Peng Y, Zhang Z, Liu J, Zhang Y, Jin ZB, Liang Q
Investigative ophthalmology & visual science 2023 Mar 1;64(3):6
Investigative ophthalmology & visual science 2023 Mar 1;64(3):6
USP1/UAF1-Stabilized METTL3 Promotes Reactive Astrogliosis and Improves Functional Recovery after Spinal Cord Injury through m(6)A Modification of YAP1 mRNA.
Ge X, Ye W, Zhu Y, Cui M, Zhou J, Xiao C, Jiang D, Tang P, Wang J, Wang Z, Ji C, Zhou X, Cao X, Liu W, Cai W
The Journal of neuroscience : the official journal of the Society for Neuroscience 2023 Mar 1;43(9):1456-1474
The Journal of neuroscience : the official journal of the Society for Neuroscience 2023 Mar 1;43(9):1456-1474
Effects and mechanisms of Xiaochaihu Tang against liver fibrosis: An integration of network pharmacology, molecular docking and experimental validation.
Wang SJ, Ye W, Li WY, Tian W, Zhang M, Sun Y, Feng YD, Liu CX, Liu SY, Cao W, Meng JR, Li XQ
Journal of ethnopharmacology 2023 Mar 1;303:116053
Journal of ethnopharmacology 2023 Mar 1;303:116053
Experimental study of miR-503 regulating the activity as well as the function of degenerated human nucleus pulposus cells of the intervertebral disc through inhibiting Wnt pathway.
Shi X, Tian S, Tian Y
Journal of musculoskeletal & neuronal interactions 2023 Mar 1;23(1):131-144
Journal of musculoskeletal & neuronal interactions 2023 Mar 1;23(1):131-144
FtMt reduces oxidative stress-induced trophoblast cell dysfunction via the HIF-1α/VEGF signaling pathway.
Xu X, Ye X, Zhu M, Zhang Q, Li X, Yan J
BMC pregnancy and childbirth 2023 Mar 1;23(1):131
BMC pregnancy and childbirth 2023 Mar 1;23(1):131
USP39 Regulates NF-κB-Mediated Inflammatory Responses through Deubiquitinating K48-Linked IκBα.
Quan J, Zhao X, Xiao Y, Wu H, Di Q, Wu Z, Chen X, Tang H, Zhao J, Guan Y, Xu Y, Chen W
Journal of immunology (Baltimore, Md. : 1950) 2023 Mar 1;210(5):640-652
Journal of immunology (Baltimore, Md. : 1950) 2023 Mar 1;210(5):640-652
Polydatin Alleviates Chronic Stress-Induced Depressive and Anxiety-like Behaviors in a Mouse Model.
Wang J, Men Y, Wang Z
ACS chemical neuroscience 2023 Mar 1;14(5):977-987
ACS chemical neuroscience 2023 Mar 1;14(5):977-987
Disease-associated mutations in WDR34 lead to diverse impacts on the assembly and function of dynein-2.
Shak C, Vuolo L, Uddin B, Katoh Y, Brown T, Mukhopadhyay AG, Heesom K, Roberts AJ, Stevenson N, Nakayama K, Stephens DJ
Journal of cell science 2023 Mar 1;136(5)
Journal of cell science 2023 Mar 1;136(5)
The tick saliva peptide HIDfsin2 promotes the tick-borne virus SFTSV replication in vitro by enhancing p38 signal pathway.
Wang L, Sun F, Hu J, Zuo W, Zheng Y, Wu Y, Kwok HF, Cao Z
Archives of toxicology 2023 Jun;97(6):1783-1794
Archives of toxicology 2023 Jun;97(6):1783-1794
PACT inhibits the replication of SARS-CoV-2 through the blockage of GSK-3β-N-nsp3 cascade.
Lin YY, Yao R, Zhuang J, Wang B, Du L, Guo D, Pan JA, Peng X
Journal of medical virology 2023 Jun;95(6):e28832
Journal of medical virology 2023 Jun;95(6):e28832
Preterm birth alters the feeding-induced activation of Akt signaling in the muscle of neonatal piglets.
Suryawan A, Rudar M, Naberhuis JK, Fiorotto ML, Davis TA
Pediatric research 2023 Jun;93(7):1891-1898
Pediatric research 2023 Jun;93(7):1891-1898
M6A modification promotes blood-brain barrier breakdown during cerebral ischemia/reperfusion injury through increasing matrix metalloproteinase 3 expression.
Liang E, Xiao S, Zhao C, Zhang Y, Fu G
Heliyon 2023 Jun;9(6):e16905
Heliyon 2023 Jun;9(6):e16905
Benzylisoquinoline alkaloids inhibit lung fibroblast activation mainly via inhibiting TGF-β1/Smads and ERK1/2 pathway proteins.
Ren HL, Zhang JH, Xiao JH
Heliyon 2023 Jun;9(6):e16849
Heliyon 2023 Jun;9(6):e16849
Preoperative fibrinogen is associated with the clinical survival of primary liver cancer patients and promotes hepatoma metastasis via the PTEN/AKT/mTOR pathway.
Qian X, Cai J, Qi Q, Han J, Zhu X, Xia R, Zhang Q
Heliyon 2023 Jun;9(6):e16696
Heliyon 2023 Jun;9(6):e16696
Cinepazide maleate promotes recovery from spinal cord injury by inhibiting inflammation and prolonging neuronal survival.
Li D, Zhao S, Zhu B, Zhao W, Ding Y, Li X, Fu D, Yu H, Wang B, Pan T
Drug development research 2023 Jun;84(4):736-746
Drug development research 2023 Jun;84(4):736-746
Role of histone deacetylase 9 in human periodontal ligament stem cells autophagy in a tumour necrosis factor α-induced inflammatory environment.
Ge W, Luo S, Zhang K, Liu L, Zhou Z, Liu Y
Tissue & cell 2023 Jun;82:102113
Tissue & cell 2023 Jun;82:102113
Protective effects of electroacupuncture on polycystic ovary syndrome in rats: Down-regulating Alas2 to inhibit apoptosis, oxidative stress, and mitochondrial dysfunction in ovarian granulosa cells.
Cong J, Li M, Wang Y, Ma H, Yang X, Gao J, Wang L, Wu X
Tissue & cell 2023 Jun;82:102090
Tissue & cell 2023 Jun;82:102090
8-methoxypsoralen protects against acetaminophen-induced liver injury by antagonising Cyp2e1 in mice.
Liu S, Cheng R, He H, Ding K, Zhang R, Chai Y, Yu Q, Huang X, Zhang L, Jiang Z
Archives of biochemistry and biophysics 2023 Jun;741:109617
Archives of biochemistry and biophysics 2023 Jun;741:109617
Tumor-derived extracellular vesicles delivering TNF-α promotes colorectal cancer metastasis via the NF-kB/LAMB3/AKT axis by targeting SNAP23.
Xie BW, Guan B, Chen W, Zhou M, Gu Q, Liu Y, Yan D
Archives of biochemistry and biophysics 2023 Jun;741:109605
Archives of biochemistry and biophysics 2023 Jun;741:109605
Small peptide LINC00511-133aa encoded by LINC00511 regulates breast cancer cell invasion and stemness through the Wnt/β-catenin pathway.
Tan Z, Zhao L, Huang S, Jiang Q, Wei Y, Wu JL, Zhang Z, Li Y
Molecular and cellular probes 2023 Jun;69:101913
Molecular and cellular probes 2023 Jun;69:101913
UTP11 deficiency suppresses cancer development via nucleolar stress and ferroptosis.
Gan Y, Deng J, Hao Q, Huang Y, Han T, Xu JG, Zhao M, Yao L, Xu Y, Xiong J, Lu H, Wang C, Chen J, Zhou X
Redox biology 2023 Jun;62:102705
Redox biology 2023 Jun;62:102705
Accumulated cholesterol protects tumours from elevated lipid peroxidation in the microenvironment.
Zhao X, Lian X, Xie J, Liu G
Redox biology 2023 Jun;62:102678
Redox biology 2023 Jun;62:102678
ROS promote hyper-methylation of NDRG2 promoters in a DNMTS-dependent manner: Contributes to the progression of renal fibrosis.
Zhao Y, Fan X, Wang Q, Zhen J, Li X, Zhou P, Lang Y, Sheng Q, Zhang T, Huang T, Zhao Y, Lv Z, Wang R
Redox biology 2023 Jun;62:102674
Redox biology 2023 Jun;62:102674
Extracellular CIRP Induces Calpain Activation in Neurons via PLC-IP(3)-Dependent Calcium Pathway.
Sharma A, Sari E, Lee Y, Patel S, Brenner M, Marambaud P, Wang P
Molecular neurobiology 2023 Jun;60(6):3311-3328
Molecular neurobiology 2023 Jun;60(6):3311-3328
Ndufa4 Regulates the Proliferation and Apoptosis of Neurons via miR-145a-5p/Homer1/Ccnd2.
Fu F, Chen C, Du K, Li LS, Li R, Lei TY, Deng Q, Wang D, Yu QX, Yang X, Han J, Pan M, Zhen L, Zhang LN, Li J, Li FT, Zhang YL, Jing XY, Li FC, Li DZ, Liao C
Molecular neurobiology 2023 Jun;60(6):2986-3003
Molecular neurobiology 2023 Jun;60(6):2986-3003
The MIR34B/C genomic region contains multiple potential regulators of multiciliogenesis.
Cavard A, Redman E, Mercey O, Abelanet S, Plaisant M, Arguel MJ, Magnone V, Ruiz García S, Rios G, Deprez M, Lebrigand K, Ponzio G, Caballero I, Barbry P, Zaragosi LE, Marcet B
FEBS letters 2023 Jun;597(12):1623-1637
FEBS letters 2023 Jun;597(12):1623-1637
STAT2/Caspase3 in the diagnosis and treatment of psoriasis.
Fu Z, He Y, Gao L, Tong X, Zhou L, Zeng J
European journal of clinical investigation 2023 Jun;53(6):e13959
European journal of clinical investigation 2023 Jun;53(6):e13959
Blocking Two-Pore Domain Potassium Channel TREK-1 Inhibits the Activation of A1-Like Reactive Astrocyte Through the NF-κB Signaling Pathway in a Rat Model of Major Depressive Disorder.
Cong T, Sun Y, Zhou Y, Wu H, Li L, Chu Z, Chen X, Li J, Zhao D, Wang Y, Liu Y, Yin S, Xiao Z
Neurochemical research 2023 Jun;48(6):1737-1754
Neurochemical research 2023 Jun;48(6):1737-1754
Chlorogenic Acid Alleviates Hepatic Ischemia-Reperfusion Injury by Inhibiting Oxidative Stress, Inflammation, and Mitochondria-Mediated Apoptosis In Vivo and In Vitro.
Li K, Feng Z, Wang L, Ma X, Wang L, Liu K, Geng X, Peng C
Inflammation 2023 Jun;46(3):1061-1076
Inflammation 2023 Jun;46(3):1061-1076
Porcupine inhibitor CGX1321 alleviates heart failure with preserved ejection fraction in mice by blocking WNT signaling.
Wu H, Tang LX, Wang XM, Li LP, Chen XK, He YJ, Yang DZ, Shi Y, Shou JL, Zhang ZS, Wang L, Lu BJ, An SM, Zeng CY, Wang WE
Acta pharmacologica Sinica 2023 Jun;44(6):1149-1160
Acta pharmacologica Sinica 2023 Jun;44(6):1149-1160
DOCK2 Deficiency Attenuates Abdominal Aortic Aneurysm Formation-Brief Report.
Guo X, Cai D, Dong K, Li C, Xu Z, Chen SY
Arteriosclerosis, thrombosis, and vascular biology 2023 Jun;43(6):e210-e217
Arteriosclerosis, thrombosis, and vascular biology 2023 Jun;43(6):e210-e217
Age-related Changes in Humanin Expression in the Ovarian Tissue of Rat.
Xia Y, Zhang HY, Ma S, Zhou F
Current medical science 2023 Jun;43(3):579-584
Current medical science 2023 Jun;43(3):579-584
ARID1A Inactivation Increases Expression of circ0008399 and Promotes Cisplatin Resistance in Bladder Cancer.
Jiang YK, Shuai YJ, Ding HM, Zhang H, Huang C, Wang L, Sun JY, Wei WJ, Xiao XY, Jiang GS
Current medical science 2023 Jun;43(3):560-571
Current medical science 2023 Jun;43(3):560-571
ZNF133 is a potent suppressor in breast carcinogenesis through dampening L1CAM, a driver for tumor progression.
Li L, Wang X, Hu K, Liu X, Qiu L, Bai C, Cui Y, Wang B, Wang Z, Wang H, Cheng R, Hua J, Hai L, Wang M, Liu M, Song Z, Xiao C, Li B
Oncogene 2023 Jun;42(27):2166-2182
Oncogene 2023 Jun;42(27):2166-2182
Comprehensive landscape of TGFβ-related signature in osteosarcoma for predicting prognosis, immune characteristics, and therapeutic response.
Liu D, Peng Y, Li X, Zhu Z, Mi Z, Zhang Z, Fan H
Journal of bone oncology 2023 Jun;40:100484
Journal of bone oncology 2023 Jun;40:100484
CaMKII and Ca(V)3.2 T-type calcium channel mediate Connexin-43-dependent inflammation by activating astrocytes in vincristine-induced neuropathic pain.
Li GZ, Hu YH, Lu YN, Yang QY, Fu D, Chen F, Li YM
Cell biology and toxicology 2023 Jun;39(3):679-702
Cell biology and toxicology 2023 Jun;39(3):679-702
Employing single valency polyphenol to prepare metal-phenolic network antitumor reagents through FeOOH assistance.
Zhang M, Wang L, Jin H, Zhao N, Liu Y, Lan S, Liu S, Zhang H
Journal of controlled release : official journal of the Controlled Release Society 2023 Jun;358:612-625
Journal of controlled release : official journal of the Controlled Release Society 2023 Jun;358:612-625
Silencing of TMED5 inhibits proliferation, migration and invasion, and enhances apoptosis of hepatocellular carcinoma cells.
Cheng X, Deng X, Zeng H, Zhou T, Li D, Zheng WV
Advances in clinical and experimental medicine : official organ Wroclaw Medical University 2023 Jun;32(6):677-688
Advances in clinical and experimental medicine : official organ Wroclaw Medical University 2023 Jun;32(6):677-688
Molecular basis of the TRAP complex function in ER protein biogenesis.
Jaskolowski M, Jomaa A, Gamerdinger M, Shrestha S, Leibundgut M, Deuerling E, Ban N
Nature structural & molecular biology 2023 Jun;30(6):770-777
Nature structural & molecular biology 2023 Jun;30(6):770-777
Microglial targeted therapy relieves cognitive impairment caused by Cntnap4 deficiency.
Zhang W, Chen H, Ding L, Huang J, Zhang M, Liu Y, Ma R, Zheng S, Gong J, Piña-Crespo JC, Zhang Y
Exploration (Beijing, China) 2023 Jun;3(3):20220160
Exploration (Beijing, China) 2023 Jun;3(3):20220160
Protective Effect and Mechanism of Kuntai Capsule on Angiotensin II -Induced Hypertension in Ovariectomized Rats.
Ge XF, Li SS, Liu YH, Lu MQ, Su HN, Yang X, Sun XW
Chinese journal of integrative medicine 2023 Jun;29(6):526-533
Chinese journal of integrative medicine 2023 Jun;29(6):526-533
Acanthopanax senticosus extract alleviates radiation-induced learning and memory impairment based on neurotransmitter-gut microbiota communication.
Song C, Yin Y, Qin Y, Li T, Zeng D, Ju T, Duan F, Zhang Y, Lu W
CNS neuroscience & therapeutics 2023 Jun;29 Suppl 1(Suppl 1):129-145
CNS neuroscience & therapeutics 2023 Jun;29 Suppl 1(Suppl 1):129-145
Newcastle disease virus activates methylation-related enzymes to reprogram m(6)A methylation in infected cells.
Yuan W, Hou Y, Wang Q, Lv T, Ren J, Fan L, Cai J, Xiang B, Lin Q, Liao M, Ding C, Chen L, Ren T
Veterinary microbiology 2023 Jun;281:109747
Veterinary microbiology 2023 Jun;281:109747
Early activation of cellular stress and death pathways caused by cytoplasmic TDP-43 in the rNLS8 mouse model of ALS and FTD.
Luan W, Wright AL, Brown-Wright H, Le S, San Gil R, Madrid San Martin L, Ling K, Jafar-Nejad P, Rigo F, Walker AK
Molecular psychiatry 2023 Jun;28(6):2445-2461
Molecular psychiatry 2023 Jun;28(6):2445-2461
An mRNA processing pathway suppresses metastasis by governing translational control from the nucleus.
Navickas A, Asgharian H, Winkler J, Fish L, Garcia K, Markett D, Dodel M, Culbertson B, Miglani S, Joshi T, Yin K, Nguyen P, Zhang S, Stevers N, Hwang HW, Mardakheh F, Goga A, Goodarzi H
Nature cell biology 2023 Jun;25(6):892-903
Nature cell biology 2023 Jun;25(6):892-903
De novo pyrimidine biosynthetic complexes support cancer cell proliferation and ferroptosis defence.
Yang C, Zhao Y, Wang L, Guo Z, Ma L, Yang R, Wu Y, Li X, Niu J, Chu Q, Fu Y, Li B
Nature cell biology 2023 Jun;25(6):836-847
Nature cell biology 2023 Jun;25(6):836-847
Role of p53 in promoting BMP9‑induced osteogenic differentiation of mesenchymal stem cells through TGF‑β1.
Yao X, Li P, Deng Y, Yang Y, Luo H, He B
Experimental and therapeutic medicine 2023 Jun;25(6):248
Experimental and therapeutic medicine 2023 Jun;25(6):248
SHCBP1 contributes to the proliferation and self‑renewal of cervical cancer cells and activation of the NF‑κB signaling pathway through EIF5A.
Deng B, Li A, Zhu Y, Zhou Y, Fei J, Miao Y
Oncology letters 2023 Jun;25(6):246
Oncology letters 2023 Jun;25(6):246
HnRNPAB is an independent prognostic factor in non‑small cell lung cancer and is involved in cell proliferation and metastasis.
Wang Q, Gou X, Liu L, Zhang T, Yuan H, Zhao Y, Xie Y, Zhou J, Song K
Oncology letters 2023 Jun;25(6):215
Oncology letters 2023 Jun;25(6):215
MicroRNA26a Overexpression Hastens Osteoblast Differentiation Capacity in Dental Stem Cells.
Kaufman S, Chang P, Pendleton E, Chandar N
Cellular reprogramming 2023 Jun;25(3):109-120
Cellular reprogramming 2023 Jun;25(3):109-120
The Role of PGK1 in Promoting Ischemia/Reperfusion Injury-Induced Microglial M1 Polarization and Inflammation by Regulating Glycolysis.
Cao W, Feng Z, Zhu D, Li S, Du M, Ye S, Qi D, Li P, Chen Y, Fang Y
Neuromolecular medicine 2023 Jun;25(2):301-311
Neuromolecular medicine 2023 Jun;25(2):301-311
Luteolin ameliorates cornea stromal collagen degradation and inflammatory damage in rats with corneal alkali burn.
Wang H, Guo Z, Liu P, Yang X, Li Y, Lin Y, Zhao X, Liu Y
Experimental eye research 2023 Jun;231:109466
Experimental eye research 2023 Jun;231:109466
N-Acetyl-L-Cysteine Reduces Cervical Carcinogenesis by Promoting Apoptosis.
Guo W, Jing W
Drugs in R&D 2023 Jun;23(2):165-174
Drugs in R&D 2023 Jun;23(2):165-174
Ent-kauranes and ent-atisanes from Euphorbia wallichii and their anti-inflammatory activity.
Wang Y, Jiang Q, Sun D, Zhang N, Lin Y, Li H, Chen L
Phytochemistry 2023 Jun;210:113643
Phytochemistry 2023 Jun;210:113643
CBX7 Rejuvenates Late Passage Dental Pulp Stem Cells by Maintaining Stemness and Pro-angiogenic Ability.
Wu Y, Li B, Yu D, Zhou Z, Shen M, Jiang F
Tissue engineering and regenerative medicine 2023 Jun;20(3):473-488
Tissue engineering and regenerative medicine 2023 Jun;20(3):473-488
The COPS3-FOXO3 positive feedback loop regulates autophagy to promote cisplatin resistance in osteosarcoma.
Niu J, Yan T, Guo W, Wang W, Ren T, Huang Y, Zhao Z, Yu Y, Chen C, Huang Q, Lou J, Guo L
Autophagy 2023 Jun;19(6):1693-1710
Autophagy 2023 Jun;19(6):1693-1710
Co-targeting of ACK1 and KIT triggers additive anti-proliferative and -migration effects in imatinib-resistant gastrointestinal stromal tumors.
He W, Xu L, Ding J, Song L, Yang W, Klooster I, Pilco-Janeta DF, Serrano C, Fang H, Jiang G, Wang X, Yu J, Ou WB
Biochimica et biophysica acta. Molecular basis of disease 2023 Jun;1869(5):166690
Biochimica et biophysica acta. Molecular basis of disease 2023 Jun;1869(5):166690
Charged multivesicular body protein 2B ameliorates biliary injury in the liver from donation after cardiac death rats via autophagy with air-oxygenated normothermic machine perfusion.
Bai Y, Shi JH, Liu Q, Yang DJ, Yan ZP, Zhang JK, Tang HW, Guo WZ, Jin Y, Zhang SJ
Biochimica et biophysica acta. Molecular basis of disease 2023 Jun;1869(5):166686
Biochimica et biophysica acta. Molecular basis of disease 2023 Jun;1869(5):166686
5'-tiRNA-Gln inhibits hepatocellular carcinoma progression by repressing translation through the interaction with eukaryotic initiation factor 4A-I.
Wu C, Liu D, Zhang L, Wang J, Ding Y, Sun Z, Wang W
Frontiers of medicine 2023 Jun;17(3):476-492
Frontiers of medicine 2023 Jun;17(3):476-492
Protective effects of methylprednisolone-cyclophosphamide treatment on bleomycin-induced pulmonary fibrosis.
Xu Q, Zhu W, Tang M, Zhang M, Liu Y, Li Z, Rao Z, He X, Ma R, Xue X
Cytokine 2023 Jun;166:156188
Cytokine 2023 Jun;166:156188
COUP-TFII plays a role in cAMP-induced Schwann cell differentiation and in vitro myelination by up-regulating Krox20.
Han SH, Kim YH, Park SJ, Cho JG, Shin YK, Hong YB, Yun J, Han JY, Park HT, Park JI
Journal of neurochemistry 2023 Jun;165(5):660-681
Journal of neurochemistry 2023 Jun;165(5):660-681
Tetramethylpyrazine-Rhein Derivative inhibits the migration of canine inflammatory mammary carcinoma cells by mitochondrial damage-mediated apoptosis and cadherins downregulation.
Li X, Lin Z, Wang P, Zhou C, Xu J, Lin J, Lin D, Zhang D
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Jun;162:114731
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Jun;162:114731
Liensinine prevents ischemic injury following myocardial infarction via inhibition of Wnt/β‑catenin signaling activation.
Shen F, Wu C, Zhong X, Ma E, Peng J, Zhu W, Wo D, Ren DN
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Jun;162:114675
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Jun;162:114675
NHWD-1062 ameliorates inflammation and proliferation by the RIPK1/NF-κB/TLR1 axis in Psoriatic Keratinocytes.
Guo Y, Jin L, Dong L, Zhang M, Kuang Y, Chen X, Zhu W, Yin M
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Jun;162:114638
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Jun;162:114638
Senomorphic effect of diphenyleneiodonium through AMPK/MFF/DRP1 mediated mitochondrial fission.
Liao KM, Chen CJ, Luo WJ, Hsu CW, Yu SL, Yang PC, Su KY
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Jun;162:114616
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Jun;162:114616
Sitagliptin inhibits the survival, stemness and autophagy of glioma cells, and enhances temozolomide cytotoxicity.
You F, Li C, Zhang S, Zhang Q, Hu Z, Wang Y, Zhang T, Meng Q, Yu R, Gao S
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Jun;162:114555
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Jun;162:114555
A comprehensive analysis of single-cell RNA transcriptome reveals unique SPP1+ chondrocytes in human osteoarthritis.
Qu Y, Wang Y, Wang S, Yu X, He Y, Lu R, Chen S, Meng C, Xu H, Pei W, Ni B, Zhang R, Huang X, You H
Computers in biology and medicine 2023 Jun;160:106926
Computers in biology and medicine 2023 Jun;160:106926
Folate metabolism negatively regulates OAS-mediated antiviral innate immunity via ADAR3/endogenous dsRNA pathway.
Wu J, You Q, Lyu R, Qian Y, Tao H, Zhang F, Cai Y, Jiang N, Zheng N, Chen D, Wu Z
Metabolism: clinical and experimental 2023 Jun;143:155526
Metabolism: clinical and experimental 2023 Jun;143:155526
Hedgehog pathway orchestrates the interplay of histone modifications and tailors combination epigenetic therapies in breast cancer.
Wang X, Xu J, Sun Y, Cao S, Zeng H, Jin N, Shou M, Tang S, Chen Y, Huang M
Acta pharmaceutica Sinica. B 2023 Jun;13(6):2601-2612
Acta pharmaceutica Sinica. B 2023 Jun;13(6):2601-2612
PES1 is a biomarker of head and neck squamous cell carcinoma and is associated with the tumor microenvironment.
He Y, Xiang J, Li Y, Huang W, Gu F, Wang Y, Chen R
Cancer medicine 2023 Jun;12(11):12622-12638
Cancer medicine 2023 Jun;12(11):12622-12638
Stevioside protects primary articular chondrocytes against IL-1β-induced inflammation and catabolism by targeting integrin.
Wan J, Zhu Z, He Z, Wu H, Chen A, Zhu W, Cheng P
International immunopharmacology 2023 Jun;119:110261
International immunopharmacology 2023 Jun;119:110261
Nuciferine improves random skin flap survival via TFEB-mediated activation of autophagy-lysosomal pathway.
Xue K, Zhang G, Zhou Y, Wang K, Yao Z, Chen J, Zhang Y, Li Z, Li Z, Zheng Z, Feng Y, Mao C, Lin C, Xia W
International immunopharmacology 2023 Jun;119:110204
International immunopharmacology 2023 Jun;119:110204
Isobavachalcone ameliorates the progression of osteoarthritis by suppressing NF-κB signaling pathway.
Guo Q, Zhang M, Dong Y, Liu K, Wang D, Zheng J
International immunopharmacology 2023 Jun;119:110102
International immunopharmacology 2023 Jun;119:110102
Vitamin D receptor regulates transcription of mitochondrial DNA and directly interacts with mitochondrial DNA and TFAM.
Gezen-Ak D, Alaylıoğlu M, Yurttaş Z, Çamoğlu T, Şengül B, İşler C, Yaşar Kına Ü, Keskin E, Atasoy İL, Kafardar AM, Uzan M, Annweiler C, Dursun E
The Journal of nutritional biochemistry 2023 Jun;116:109322
The Journal of nutritional biochemistry 2023 Jun;116:109322
In vivo CRISPR screens identify RhoV as a pro-metastasis factor of triple-negative breast cancer.
Jin ML, Gong Y, Ji P, Hu X, Shao ZM
Cancer science 2023 Jun;114(6):2375-2385
Cancer science 2023 Jun;114(6):2375-2385
Differences in p38-STAT3-S100A11 signaling after the administration of aristolochic acid I and IVa may account for the disparity in their nephrotoxicity.
Xian Z, Tian J, Zhao Y, Yi Y, Li C, Han J, Zhang Y, Wang Y, Wang L, Liu S, Pan C, Liu C, Wang D, Meng J, Tang X, Wang F, Liang A
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Jun;114:154815
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Jun;114:154815
Moshen granule ameliorates membranous nephropathy by blocking intrarenal renin-angiotensin system signalling via the Wnt1/β-catenin pathway.
Wang YN, Miao H, Hua MR, Yang JZ, Pei M, Yu HX, Wei LJ, Zou L, Zhang YM, Cao G, Zhao YY
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Jun;114:154763
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Jun;114:154763
Gβγ signaling regulates microtubule-dependent control of Golgi integrity.
Rajanala K, Wedegaertner PB
Cellular signalling 2023 Jun;106:110630
Cellular signalling 2023 Jun;106:110630
Intrahippocampal injection of IL-1β upregulates Siah1-mediated degradation of synaptophysin by activation of the ERK signaling in male rat.
Zhou Q, Lin L, Li H, Li Y, Liu N, Wang H, Jiang S, Li Q, Chen Z, Lin Y, Jin H, Deng Y
Journal of neuroscience research 2023 Jun;101(6):930-951
Journal of neuroscience research 2023 Jun;101(6):930-951
Remodeling Collagen Microenvironment in Liver Using a Biomimetic Nano-Regulator for Reversal of Liver Fibrosis.
Liang Y, Wang J, Xu C, Han W, Wu S, Wu Y, Zhang J, Liu J, Zhang Z, Shi J, Zhang K
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Jun;10(18):e2300127
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Jun;10(18):e2300127
New Cases and Mutations in SEC23B Gene Causing Congenital Dyserythropoietic Anemia Type II.
Musri MM, Venturi V, Ferrer-Cortès X, Romero-Cortadellas L, Hernández G, Leoz P, Ricard Andrés MP, Morado M, Fernández Valle MDC, Beneitez Pastor D, Ortuño Cabrero A, Moreno Gamiz M, Senent Peris L, Perez-Valencia AI, Pérez-Montero S, Tornador C, Sánchez M
International journal of molecular sciences 2023 Jun 9;24(12)
International journal of molecular sciences 2023 Jun 9;24(12)
SLC35E1 promotes keratinocyte proliferation in psoriasis by regulating zinc homeostasis.
Huang T, Chen S, Ding K, Zheng B, Lv W, Wang X, Zhong Y, Huang H, Zhang X, Ma S, Yang B, Wang X, Rong Z
Cell death & disease 2023 Jun 9;14(6):354
Cell death & disease 2023 Jun 9;14(6):354
Syk-dependent alternative homologous recombination activation promotes cancer resistance to DNA targeted therapy.
Zhou Q, Tu X, Hou X, Yu J, Zhao F, Huang J, Kloeber J, Olson A, Gao M, Luo K, Zhu S, Wu Z, Zhang Y, Sun C, Zeng X, Schoolmeester K, Weroha J, Wang L, Mutter R, Lou Z
Research square 2023 Jun 9;
Research square 2023 Jun 9;
SIRT1 Activator E1231 Alleviates Nonalcoholic Fatty Liver Disease by Regulating Lipid Metabolism.
Han J, Li S, Wang W, Jiang X, Liu C, Lei L, Li Y, Sheng R, Zhang Y, Wu Y, Zhang J, Zhang Y, Xu Y, Si S
Current issues in molecular biology 2023 Jun 8;45(6):5052-5070
Current issues in molecular biology 2023 Jun 8;45(6):5052-5070
Low-intensity focused ultrasound ameliorates depression-like behaviors associated with improving the synaptic plasticity in the vCA1-mPFC pathway.
Wang F, Cai Q, Ju R, Wang S, Liu L, Pan M, Sun N, Wang X, Wang L, Yang J, Zheng C, Ming D
Cerebral cortex (New York, N.Y. : 1991) 2023 Jun 8;33(12):8024-8034
Cerebral cortex (New York, N.Y. : 1991) 2023 Jun 8;33(12):8024-8034
tsRNA-04002 alleviates intervertebral disk degeneration by targeting PRKCA to inhibit apoptosis of nucleus pulposus cells.
Pan J, Liu Z, Shen B, Xu J, Dai G, Xu W, Wang J, Li L, Cheng L
Journal of orthopaedic surgery and research 2023 Jun 7;18(1):413
Journal of orthopaedic surgery and research 2023 Jun 7;18(1):413
Pien-Tze-Huang prevents hepatocellular carcinoma by inducing ferroptosis via inhibiting SLC7A11-GSH-GPX4 axis.
Yan X, Liu Y, Li C, Mao X, Xu T, Hu Z, Zhang C, Lin N, Lin Y, Zhang Y
Cancer cell international 2023 Jun 6;23(1):109
Cancer cell international 2023 Jun 6;23(1):109
Gastroprotective effects of ginsenoside Rh4 against ethanol-induced gastric mucosal injury by inhibiting the MAPK/NF-κB signaling pathway.
Wu Y, Duan Z, Qu L, Zhang Y, Zhu C, Fan D
Food & function 2023 Jun 6;14(11):5167-5181
Food & function 2023 Jun 6;14(11):5167-5181
ZIM1 Combined with Hydrogel Inhibits Senescence of Primary PαS Cells during In Vitro Expansion.
Tian Y, Hu M, Liu X, Wang X, Lu D, Li Z, Liu Y, Zhang P, Zhou Y
International journal of molecular sciences 2023 Jun 5;24(11)
International journal of molecular sciences 2023 Jun 5;24(11)
Identification of the E2F1-RAD51AP1 axis as a key factor in MGMT-methylated GBM TMZ resistance.
Zhou J, Tong F, Zhao J, Cui X, Wang Y, Wang G, Kang C, Liu X, Wang Q
Cancer biology & medicine 2023 Jun 5;20(5):385-400
Cancer biology & medicine 2023 Jun 5;20(5):385-400
Allele-specific gene-editing approach for vision loss restoration in RHO-associated retinitis pigmentosa.
Liu X, Qiao J, Jia R, Zhang F, Meng X, Li Y, Yang L
eLife 2023 Jun 5;12
eLife 2023 Jun 5;12
Selenoproteins synergistically protect porcine skeletal muscle from oxidative damage via relieving mitochondrial dysfunction and endoplasmic reticulum stress.
Jing J, He Y, Liu Y, Tang J, Wang L, Jia G, Liu G, Chen X, Tian G, Cai J, Che L, Kang B, Zhao H
Journal of animal science and biotechnology 2023 Jun 4;14(1):79
Journal of animal science and biotechnology 2023 Jun 4;14(1):79
Isoproterenol pre-treatment improve the therapeutic efficacy of cardiosphere-derived cells transplantation for myocardial infarction.
Duan X, Yang J, Zhang W, Yang X, Xia Y, Gan S, Kuang S, Cheng X, Xie S, Liu Y
Journal of thoracic disease 2023 Jun 30;15(6):3089-3105
Journal of thoracic disease 2023 Jun 30;15(6):3089-3105
AAV9-Tspyl2 gene therapy retards bleomycin-induced pulmonary fibrosis by modulating downstream TGF-β signaling in mice.
Zhang S, Tong X, Liu S, Huang J, Zhang L, Zhang T, Wang D, Fan H
Cell death & disease 2023 Jun 30;14(6):389
Cell death & disease 2023 Jun 30;14(6):389
Role of Enzymic Antioxidants in Mediating Oxidative Stress and Contrasting Wound Healing Capabilities in Oral Mucosal/Skin Fibroblasts and Tissues.
Lohana P, Suryaprawira A, Woods EL, Dally J, Gait-Carr E, Alaidaroos NYA, Heard CM, Lee KY, Ruge F, Farrier JN, Enoch S, Caley MP, Peake MA, Davies LC, Giles PJ, Thomas DW, Stephens P, Moseley R
Antioxidants (Basel, Switzerland) 2023 Jun 30;12(7)
Antioxidants (Basel, Switzerland) 2023 Jun 30;12(7)
DnaJC7 specifically regulates tau seeding.
Perez VA, Sanders DW, Mendoza-Oliva A, Stopschinski BE, Mullapudi V, White CL, Joachimiak LA, Diamond MI
eLife 2023 Jun 30;12
eLife 2023 Jun 30;12
Kremen2 drives the progression of non-small cell lung cancer by preventing SOCS3-mediated degradation of EGFR.
Sun Y, Gao Y, Dong M, Li J, Li X, He N, Song H, Zhang M, Ji K, Wang J, Gu Y, Wang Y, Du L, Liu Y, Wang Q, Zhai H, Sun D, Liu Q, Xu C
Journal of experimental & clinical cancer research : CR 2023 Jun 3;42(1):140
Journal of experimental & clinical cancer research : CR 2023 Jun 3;42(1):140
Amelioration of olfactory dysfunction in a mouse model of Parkinson's disease via enhancing GABAergic signaling.
Liu XY, Wang K, Deng XH, Wei YH, Guo R, Liu SF, Zhu YF, Zhong JJ, Zheng JY, Wang MD, Ye QH, He JQ, Guo KH, Zhu JR, Huang SQ, Chen ZX, Lv CS, Wen L
Cell & bioscience 2023 Jun 3;13(1):101
Cell & bioscience 2023 Jun 3;13(1):101
FAK inhibitor PF-562271 inhibits the migration and proliferation of high-grade serous ovarian cancer cells through FAK and FAK mediated cell cycle arrest.
Pan Q, Wang Q, Zhao T, Zhao X, Liang Y, Shi M, Chen C, Lin F
Medical oncology (Northwood, London, England) 2023 Jun 29;40(8):215
Medical oncology (Northwood, London, England) 2023 Jun 29;40(8):215
Calcium/calmodulin dependent protein kinase IV in trophoblast cells under insulin resistance: functional and metabolomic analyses.
Li L, Li L, Shao Y, Du R, Li L, Shi X, Bai Y
Molecular medicine (Cambridge, Mass.) 2023 Jun 29;29(1):82
Molecular medicine (Cambridge, Mass.) 2023 Jun 29;29(1):82
Paradoxical Induction of ALOX15/15B by Cortisol in Human Amnion Fibroblasts: Implications for Inflammatory Responses of the Fetal Membranes at Parturition.
Zhang F, Lu JW, Lei WJ, Li MD, Pan F, Lin YK, Wang WS, Sun K
International journal of molecular sciences 2023 Jun 29;24(13)
International journal of molecular sciences 2023 Jun 29;24(13)
Du Huo Ji Sheng Tang inhibits Notch1 signaling and subsequent NLRP3 activation to alleviate cartilage degradation in KOA mice.
Chen WJ, Zhuang Y, Peng W, Cui W, Zhang SJ, Wang JW
Chinese medicine 2023 Jun 29;18(1):80
Chinese medicine 2023 Jun 29;18(1):80
DUSP10 is a novel immune-related biomarker connected with survival and cellular proliferation in lower-grade glioma.
Xiao F, Zhu H, Guo Y, Zhang Z, Sun G, Huang K, Guo H, Hu G
Aging 2023 Jun 29;15(12):5673-5697
Aging 2023 Jun 29;15(12):5673-5697
METTL14 regulates chromatin bivalent domains in mouse embryonic stem cells.
Mu M, Li X, Dong L, Wang J, Cai Q, Hu Y, Wang D, Zhao P, Zhang L, Zhang D, Cheng S, Tan L, Wu F, Shi YG, Xu W, Shi Y, Shen H
Cell reports 2023 Jun 27;42(6):112650
Cell reports 2023 Jun 27;42(6):112650
Salvianolic Acid C Inhibits the Epithelial-Mesenchymal Transition and Ameliorates Renal Tubulointerstitial Fibrosis.
Wu M, Lin J, Huang D, Ye C, Chen D
Frontiers in bioscience (Landmark edition) 2023 Jun 27;28(6):121
Frontiers in bioscience (Landmark edition) 2023 Jun 27;28(6):121
High glucose promotes the progression of colorectal cancer by activating the BMP4 signaling and inhibited by glucagon-like peptide-1 receptor agonist.
Ma B, Wang X, Ren H, Li Y, Zhang H, Yang M, Li J
BMC cancer 2023 Jun 27;23(1):594
BMC cancer 2023 Jun 27;23(1):594
Tumor-Associated Fibroblast-Derived Exosomal circDennd1b Promotes Pituitary Adenoma Progression by Modulating the miR-145-5p/ONECUT2 Axis and Activating the MAPK Pathway.
Jiang Q, Lei Z, Wang Z, Wang Q, Zhang Z, Liu X, Xing B, Li S, Guo X, Liu Y, Li X, Qi Y, Shu K, Zhang H, Huang Y, Lei T
Cancers 2023 Jun 27;15(13)
Cancers 2023 Jun 27;15(13)
TRIM29 hypermethylation drives esophageal cancer progression via suppression of ZNF750.
Yi Q, Zhao Y, Xia R, Wei Q, Chao F, Zhang R, Bian P, Lv L
Cell death discovery 2023 Jun 26;9(1):191
Cell death discovery 2023 Jun 26;9(1):191
The transcription factor Stat-1 is essential for Schwann cell differentiation, myelination and myelin sheath regeneration.
Xu J, Zhang B, Cai J, Peng Q, Hu J, Askar P, Shangguan J, Su W, Zhu C, Sun H, Zhou S, Chen G, Yang X, Gu Y
Molecular medicine (Cambridge, Mass.) 2023 Jun 26;29(1):79
Molecular medicine (Cambridge, Mass.) 2023 Jun 26;29(1):79
EZH2 Gene Knockdown Inhibits Sheep Pituitary Cell Proliferation via Downregulating the AKT/ERK Signaling Pathway.
Cai Y, Chen P, Xu H, Li S, Zhao B, Fan Y, Wang F, Zhang Y
International journal of molecular sciences 2023 Jun 26;24(13)
International journal of molecular sciences 2023 Jun 26;24(13)
Sp1 Upregulation Bolsters the Radioresistance of Glioblastoma Cells by Promoting Double Strand Breaks Repair.
Liu X, Sun C, Wang Q, Li P, Zhao T, Li Q
International journal of molecular sciences 2023 Jun 26;24(13)
International journal of molecular sciences 2023 Jun 26;24(13)
Pharmacologic inhibition of IL11/STAT3 signaling increases MHC-I expression and T cell infiltration.
Xiong W, Chen Y, Zhang C, Li J, Huang H, Zhu Y, Deng G, Cheng J, Lin Y, Shi Z, Mou T
Journal of translational medicine 2023 Jun 26;21(1):416
Journal of translational medicine 2023 Jun 26;21(1):416
ATB(0,+)-targeted nanoparticles initiate autophagy suppression to overcome chemoresistance for enhanced colorectal cancer therapy.
Chen Z, Chen H, Huang L, Duan B, Dai S, Cai W, Sun M, Jiang Z, Lu R, Jiang Y, Jiang X, Zheng H, Yao Q, Kim K, Lin G, Xie C, Chu M, Chen R, Kou L
International journal of pharmaceutics 2023 Jun 25;641:123082
International journal of pharmaceutics 2023 Jun 25;641:123082
Homocysteine induces ferroptosis in endothelial cells through the systemXc(-)/GPX4 signaling pathway.
Shi J, Chen D, Wang Z, Li S, Zhang S
BMC cardiovascular disorders 2023 Jun 24;23(1):316
BMC cardiovascular disorders 2023 Jun 24;23(1):316
Role of liensinine in sensitivity of activated macrophages to ferroptosis and in acute liver injury.
Li J, Huang Q, Lv M, Ma W, Sun J, Zhong X, Hu R, Ma M, Han Z, Zhang W, Feng W, Sun X, Zhou X
Cell death discovery 2023 Jun 23;9(1):189
Cell death discovery 2023 Jun 23;9(1):189
Engineered circular guide RNAs boost CRISPR/Cas12a- and CRISPR/Cas13d-based DNA and RNA editing.
Zhang X, Wang X, Lv J, Huang H, Wang J, Zhuo M, Tan Z, Huang G, Liu J, Liu Y, Li M, Lin Q, Li L, Ma S, Huang T, Lin Y, Zhao X, Rong Z
Genome biology 2023 Jun 23;24(1):145
Genome biology 2023 Jun 23;24(1):145
"Biqi" Bayberry Extract Promotes Skeletal Muscle Fiber Type Remodeling by Increasing Fast Myofiber Formation via the Akt/FoxO1 Pathway in Mice.
Li J, Li Y, Suo X, Li J, Huang D, Kou G
Foods (Basel, Switzerland) 2023 Jun 23;12(13)
Foods (Basel, Switzerland) 2023 Jun 23;12(13)
ATXN3 promotes prostate cancer progression by stabilizing YAP.
Wu L, Ou Z, Liu P, Zhao C, Tong S, Wang R, Li Y, Yuan J, Chen M, Fan B, Zu X, Wang Y, Tang J
Cell communication and signaling : CCS 2023 Jun 22;21(1):152
Cell communication and signaling : CCS 2023 Jun 22;21(1):152
Maternal NAT10 orchestrates oocyte meiotic cell-cycle progression and maturation in mice.
Jiang X, Cheng Y, Zhu Y, Xu C, Li Q, Xing X, Li W, Zou J, Meng L, Azhar M, Cao Y, Tong X, Qin W, Zhu X, Bao J
Nature communications 2023 Jun 22;14(1):3729
Nature communications 2023 Jun 22;14(1):3729
Differential and substrate-specific inhibition of γ-secretase by the C-terminal region of ApoE2, ApoE3, and ApoE4.
Hou X, Zhang X, Zou H, Guan M, Fu C, Wang W, Zhang ZR, Geng Y, Chen Y
Neuron 2023 Jun 21;111(12):1898-1913.e5
Neuron 2023 Jun 21;111(12):1898-1913.e5
Macrophage Dectin-1 mediates Ang II renal injury through neutrophil migration and TGF-β1 secretion.
Ye S, Huang H, Xiao Y, Han X, Shi F, Luo W, Chen J, Ye Y, Zhao X, Huang W, Wang Y, Lai D, Liang G, Fu G
Cellular and molecular life sciences : CMLS 2023 Jun 20;80(7):184
Cellular and molecular life sciences : CMLS 2023 Jun 20;80(7):184
[Lipopolysaccharide stimulates macrophages to secrete exosomes containing miR-155-5p to promote activation and migration of hepatic stellate cells].
Lin J, Lou A, Li X
Nan fang yi ke da xue xue bao = Journal of Southern Medical University 2023 Jun 20;43(6):994-1001
Nan fang yi ke da xue xue bao = Journal of Southern Medical University 2023 Jun 20;43(6):994-1001
METTL16 promotes glycolytic metabolism reprogramming and colorectal cancer progression.
Wei W, Zhang ZY, Shi B, Cai Y, Zhang HS, Sun CL, Fei YF, Zhong W, Zhang S, Wang C, He B, Jiang GM, Wang H
Journal of experimental & clinical cancer research : CR 2023 Jun 20;42(1):151
Journal of experimental & clinical cancer research : CR 2023 Jun 20;42(1):151
Panax notoginseng alleviates oxidative stress through miRNA regulations based on systems biology approach.
Tang Y, Chen YG, Huang HY, Li SF, Zuo HL, Chen JH, Li LP, Mao RB, Lin YC, Huang HD
Chinese medicine 2023 Jun 20;18(1):74
Chinese medicine 2023 Jun 20;18(1):74
ULK1-mediated metabolic reprogramming regulates Vps34 lipid kinase activity by its lactylation.
Jia M, Yue X, Sun W, Zhou Q, Chang C, Gong W, Feng J, Li X, Zhan R, Mo K, Zhang L, Qian Y, Sun Y, Wang A, Zou Y, Chen W, Li Y, Huang L, Yang Y, Zhao Y, Cheng X
Science advances 2023 Jun 2;9(22):eadg4993
Science advances 2023 Jun 2;9(22):eadg4993
The m6A Reader YTHDF2 Promotes Bladder Cancer Progression by Suppressing RIG-I-Mediated Immune Response.
Zhang L, Li Y, Zhou L, Zhou H, Ye L, Ou T, Hong H, Zheng S, Zhou Z, Wu K, Yan Z, Thiery JP, Cui J, Wu S
Cancer research 2023 Jun 2;83(11):1834-1850
Cancer research 2023 Jun 2;83(11):1834-1850
Efficient and Specific Generation of MSTN-Edited Hu Sheep Using C-CRISPR.
Guo R, Wang H, Meng C, Gui H, Li Y, Chen F, Zhang C, Zhang H, Ding Q, Zhang J, Zhang J, Qian Y, Zhong J, Cao S
Genes 2023 Jun 2;14(6)
Genes 2023 Jun 2;14(6)
Decapping factor Dcp2 controls mRNA abundance and translation to adjust metabolism and filamentation to nutrient availability.
Vijjamarri AK, Niu X, Vandermeulen MD, Onu C, Zhang F, Qiu H, Gupta N, Gaikwad S, Greenberg ML, Cullen PJ, Lin Z, Hinnebusch AG
eLife 2023 Jun 2;12
eLife 2023 Jun 2;12
EBV-Upregulated B7-H3 Inhibits NK cell-Mediated Antitumor Function and Contributes to Nasopharyngeal Carcinoma Progression.
Chen H, Duan X, Deng X, Huang Y, Zhou X, Zhang S, Zhang X, Liu P, Yang C, Liu G, Ren Q, Xiong Y, Zhu B, Zhang J, Xiang T
Cancer immunology research 2023 Jun 2;11(6):830-846
Cancer immunology research 2023 Jun 2;11(6):830-846
Regulon analysis identifies protective FXR and CREB5 in proximal tubules in early diabetic kidney disease.
Shi W, Le W, Tang Q, Shi S, Shi J
BMC nephrology 2023 Jun 19;24(1):180
BMC nephrology 2023 Jun 19;24(1):180
SETD7 promotes lateral plate mesoderm formation by modulating the Wnt/β-catenin signaling pathway.
Wang D, Li Y, Xu C, Wang H, Huang X, Jin X, Ren S, Gao J, Tong J, Liu J, Zhou J, Shi L
iScience 2023 Jun 16;26(6):106917
iScience 2023 Jun 16;26(6):106917
Inflammation conditional genome editing mediated by the CRISPR-Cas9 system.
Yuan T, Tang H, Xu X, Shao J, Wu G, Cho YC, Ping Y, Liang G
iScience 2023 Jun 16;26(6):106872
iScience 2023 Jun 16;26(6):106872
Zhx2 maintains islet β-cell mass and function by transcriptionally regulating Pax6.
Ding L, Zhang Y, Wang Y, Wang Y, Tong Z, Li P, Chen C, Wang B, Yue X, Li C, Wu Z, Liang X, Ma C, Gao L
iScience 2023 Jun 16;26(6):106871
iScience 2023 Jun 16;26(6):106871
m(6)A Regulates the Stability of Cellular Transcripts Required for Efficient KSHV Lytic Replication.
Manners O, Baquero-Perez B, Mottram TJ, Yonchev ID, Trevelyan CJ, Harper KL, Menezes S, Patterson MR, Macdonald A, Wilson SA, Aspden JL, Whitehouse A
Viruses 2023 Jun 16;15(6)
Viruses 2023 Jun 16;15(6)
TOPK promotes the growth of esophageal cancer in vitro and in vivo by enhancing YB1/eEF1A1 signal pathway.
Wu W, Xu J, Gao D, Xie Z, Chen W, Li W, Yuan Q, Duan L, Zhang Y, Yang X, Chen Y, Dong Z, Liu K, Jiang Y
Cell death & disease 2023 Jun 16;14(6):364
Cell death & disease 2023 Jun 16;14(6):364
Aminosalicylates target GPR35, partly contributing to the prevention of DSS-induced colitis.
Otkur W, Wang J, Hou T, Liu F, Yang R, Li Y, Xiang K, Pei S, Qi H, Lin H, Zhou H, Zhang X, Piao HL, Liang X
European journal of pharmacology 2023 Jun 15;949:175719
European journal of pharmacology 2023 Jun 15;949:175719
Thorium(IV) triggers ferroptosis through disrupting iron homeostasis and heme metabolism in the liver following oral ingestion.
Ma M, Wang R, Xu M
Journal of hazardous materials 2023 Jun 15;452:131217
Journal of hazardous materials 2023 Jun 15;452:131217
Berberine attenuates liver fibrosis by autophagy inhibition triggering apoptosis via the miR-30a-5p/ATG5 axis.
Tan Y, Li C, Zhou J, Deng F, Liu Y
Experimental cell research 2023 Jun 15;427(2):113600
Experimental cell research 2023 Jun 15;427(2):113600
Effects of Follicular Fluid on Physiological Characteristics and Differentiation of Fallopian Tube Epithelial Cells Implicating for Ovarian Cancer Pathogenesis.
Zhu M, Wang N, Wang S, Wang Y, Yang X, Fan J, Chen Y
International journal of molecular sciences 2023 Jun 15;24(12)
International journal of molecular sciences 2023 Jun 15;24(12)
Antidepressant effect of 4-Butyl-alpha-agarofuran via HPA axis and serotonin system.
Wang H, Hu J, Hu J, Chen Q, Shang N, Liu M, Li X, Xiang L, Yin D, Lan J, Xiao Q, Peng Y
Brain research bulletin 2023 Jun 15;198:3-14
Brain research bulletin 2023 Jun 15;198:3-14
USP1-Associated Factor 1 Modulates Japanese Encephalitis Virus Replication by Governing Autophagy and Interferon-Stimulated Genes.
Xing J, Hu C, Che S, Lan Y, Huang L, Liu L, Yin Y, Li H, Liao M, Qi W
Microbiology spectrum 2023 Jun 15;11(3):e0318622
Microbiology spectrum 2023 Jun 15;11(3):e0318622
Epstein-Barr Virus Envelope Glycoprotein gp110 Inhibits IKKi-Mediated Activation of NF-κB and Promotes the Degradation of β-Catenin.
Guo Y, Pan L, Wang L, Wang S, Fu J, Luo W, Wang K, Li X, Huang C, Liu Y, Kang H, Zeng Q, Fu X, Huang Z, Li W, He Y, Li L, Peng T, Yang H, Li M, Xiao B, Cai M
Microbiology spectrum 2023 Jun 15;11(3):e0032623
Microbiology spectrum 2023 Jun 15;11(3):e0032623
Establishment of Continuous In Vitro Culture of Babesia gibsoni by Using VP-SFM Medium with Low-Concentration Serum.
Li D, Wang L, Guan X, Wang S, Liu Q, Chen F, Zheng Y, He L, Zhao J
Microbiology spectrum 2023 Jun 15;11(3):e0025823
Microbiology spectrum 2023 Jun 15;11(3):e0025823
LncRNA ZNF593-AS alleviates diabetic cardiomyopathy via suppressing IRF3 signaling pathway.
Xie R, Fan J, Wen J, Jin K, Zhan J, Yuan S, Tang Y, Nie X, Wen Z, Li H, Chen C, Wang DW
Molecular therapy. Nucleic acids 2023 Jun 13;32:689-703
Molecular therapy. Nucleic acids 2023 Jun 13;32:689-703
TNF-α activates RELA expression via TNFRSF1B to upregulate OPA1 expression and inhibit chondrogenic differentiation of human adipose stem cells.
Guo J, Ye W, Wu X, Huang H, Li B, Sun Z, Ren Z, Yang Z
Journal of orthopaedic surgery and research 2023 Jun 13;18(1):430
Journal of orthopaedic surgery and research 2023 Jun 13;18(1):430
LSM2 is associated with a poor prognosis and promotes cell proliferation, migration, and invasion in skin cutaneous melanoma.
Sun X, Zhang J, Hu J, Han Q, Ge Z
BMC medical genomics 2023 Jun 13;16(1):129
BMC medical genomics 2023 Jun 13;16(1):129
USP8 positively regulates hepatocellular carcinoma tumorigenesis and confers ferroptosis resistance through β-catenin stabilization.
Tang J, Long G, Xiao L, Zhou L
Cell death & disease 2023 Jun 13;14(6):360
Cell death & disease 2023 Jun 13;14(6):360
Methionine restriction promotes cGAS activation and chromatin untethering through demethylation to enhance antitumor immunity.
Fang L, Hao Y, Yu H, Gu X, Peng Q, Zhuo H, Li Y, Liu Z, Wang J, Chen Y, Zhang J, Tian H, Gao Y, Gao R, Teng H, Shan Z, Zhu J, Li Z, Liu Y, Zhang Y, Yu F, Lin Z, Hao Y, Ge X, Yuan J, Hu HG, Ma Y, Qin HL, Wang P
Cancer cell 2023 Jun 12;41(6):1118-1133.e12
Cancer cell 2023 Jun 12;41(6):1118-1133.e12
Traditional Chinese Medicine Danzhi qing'e decoction inhibits inflammation-associated prostatic hyperplasia via inactivation of ERK1/2 signal pathway.
Liu Y, Shao R, Suo T, Zhu J, Liu E, Wang Y, Miao L, Gao X
Journal of ethnopharmacology 2023 Jun 12;309:116354
Journal of ethnopharmacology 2023 Jun 12;309:116354
Melatonin enhances anti-tumor immunity by targeting macrophages PD-L1 via exosomes derived from gastric cancer cells.
Wang K, Cai R, Fei S, Chen X, Feng S, Zhang L, Liu H, Zhang Z, Song J, Zhou R
Molecular and cellular endocrinology 2023 Jun 1;568-569:111917
Molecular and cellular endocrinology 2023 Jun 1;568-569:111917
LncRNA JPX targets SERCA2a to mitigate myocardial ischemia/reperfusion injury by binding to EZH2.
Bao J, Zhang C, Chen J, Xuan H, Wang C, Wang S, Yin J, Liu Y, Li D, Xu T
Experimental cell research 2023 Jun 1;427(1):113572
Experimental cell research 2023 Jun 1;427(1):113572
A Noncoding A-to-U Kozak Site Change Related to the High Transmissibility of Alpha, Delta, and Omicron VOCs.
Yang J, Cui Y, Yu D, Zhang G, Cao R, Gu Z, Dai G, Wu X, Ling Y, Yi C, Sun X, Sun B, Lin X, Zhang Y, Zhao GP, Li Y, Pan YH, Li H
Molecular biology and evolution 2023 Jun 1;40(6)
Molecular biology and evolution 2023 Jun 1;40(6)
An alternative mechanism for skeletal muscle dysfunction in long-term post-viral lung disease.
Martin RA, Keeler SP, Wu K, Shearon WJ, Patel D, Li J, Hoang M, Hoffmann CM, Hughes ME, Holtzman MJ
American journal of physiology. Lung cellular and molecular physiology 2023 Jun 1;324(6):L870-L878
American journal of physiology. Lung cellular and molecular physiology 2023 Jun 1;324(6):L870-L878
Dapagliflozin delays renal fibrosis in diabetic kidney disease by inhibiting YAP/TAZ activation.
Feng L, Chen Y, Li N, Yang X, Zhou L, Li H, Wang T, Xie M, Liu H
Life sciences 2023 Jun 1;322:121671
Life sciences 2023 Jun 1;322:121671
A Tumor-suppressive Molecular Axis EP300/circRERE/miR-6837-3p/MAVS Activates Type I IFN Pathway and Antitumor Immunity to Suppress Colorectal Cancer.
Ding N, You AB, Yang H, Hu GS, Lai CP, Liu W, Ye F
Clinical cancer research : an official journal of the American Association for Cancer Research 2023 Jun 1;29(11):2095-2109
Clinical cancer research : an official journal of the American Association for Cancer Research 2023 Jun 1;29(11):2095-2109
The ovarian-related effects of polystyrene nanoplastics on human ovarian granulosa cells and female mice.
Zeng L, Zhou C, Xu W, Huang Y, Wang W, Ma Z, Huang J, Li J, Hu L, Xue Y, Luo T, Zheng L
Ecotoxicology and environmental safety 2023 Jun 1;257:114941
Ecotoxicology and environmental safety 2023 Jun 1;257:114941
CM3-SII polysaccharide obtained from Cordyceps militaris ameliorates hyperlipidemia in heterozygous LDLR-deficient hamsters by modulating gut microbiota and NPC1L1 and PPARα levels.
Yu WQ, Wang XL, Ji HH, Miao M, Zhang BH, Li H, Zhang ZY, Ji CF, Guo SD
International journal of biological macromolecules 2023 Jun 1;239:124293
International journal of biological macromolecules 2023 Jun 1;239:124293
Tissue-resident CXCR4(+) macrophage as a poor prognosis signature promotes pancreatic ductal adenocarcinoma progression.
Liao Z, Ye L, Li T, Jin X, Lin X, Fei Q, Zhang H, Shi S, Yu X, Jin K, Wu W
International journal of cancer 2023 Jun 1;152(11):2396-2409
International journal of cancer 2023 Jun 1;152(11):2396-2409
Exercise Improves Metabolism and Alleviates Atherosclerosis via Muscle-Derived Extracellular Vesicles.
Wang Y, Liu Y, Zhang S, Li N, Xing C, Wang C, Wang J, Wei M, Yang G, Yuan L
Aging and disease 2023 Jun 1;14(3):952-965
Aging and disease 2023 Jun 1;14(3):952-965
Long noncoding RNA HITT coordinates with RGS2 to inhibit PD-L1 translation in T cell immunity.
Lin Q, Liu T, Wang X, Hou G, Xiang Z, Zhang W, Zheng S, Zhao D, Leng Q, Zhang X, Lu M, Guan T, Liu H, Hu Y
The Journal of clinical investigation 2023 Jun 1;133(11)
The Journal of clinical investigation 2023 Jun 1;133(11)
Prematurity blunts protein synthesis in skeletal muscle independently of body weight in neonatal pigs.
Rudar M, Naberhuis JK, Suryawan A, Nguyen HV, Fiorotto ML, Davis TA
Pediatric research 2023 Jul;94(1):143-152
Pediatric research 2023 Jul;94(1):143-152
Cortactin contributes to the tumorigenesis of gastric cancer by activating ERK/MMP pathway.
Zhao Y, Hu F, Wang Q
Heliyon 2023 Jul;9(7):e18289
Heliyon 2023 Jul;9(7):e18289
Identification of ALG3 as a potential prognostic biomarker in lung adenocarcinoma.
Yuan Y, Xie B, Guo D, Liu C, Jiang G, Lai G, Zhang Y, Hu X, Wu Z, Zheng R, Huang L
Heliyon 2023 Jul;9(7):e18065
Heliyon 2023 Jul;9(7):e18065
Identification of pathogenic deep intronic variant and exonic LINE-1 insertion in a patient with Meckel syndrome.
Miyamoto S, Nakamura K, Kato M, Nakashima M, Saitsu H
Annals of human genetics 2023 Jul;87(4):196-202
Annals of human genetics 2023 Jul;87(4):196-202
An iRGD-conjugated photothermal therapy-responsive gold nanoparticle system carrying siCDK7 induces necroptosis and immunotherapeutic responses in lung adenocarcinoma.
Cai R, Wang M, Liu M, Zhu X, Feng L, Yu Z, Yang X, Zhang Z, Guo H, Guo R, Zheng Y
Bioengineering & translational medicine 2023 Jul;8(4):e10430
Bioengineering & translational medicine 2023 Jul;8(4):e10430
STING deficiency protects against wasp venom-induced acute kidney injury.
Lv Y, Lu L, Yu F, Gao Z, Yuan H, Hu F
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2023 Jul;72(7):1427-1440
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2023 Jul;72(7):1427-1440
Natural Oncolysis of Enterovirus 71 in Antitumor Therapy of Colorectal Cancer.
Ruan Z, Chi J, Kong Y, Li C, Ruan X, Zhou X, Chen Y, Li Y, Luo Z
Advanced biology 2023 Jul;7(7):e2200336
Advanced biology 2023 Jul;7(7):e2200336
Zinc finger E-box binding homebox 2 alleviated experimental osteoarthritis in rats.
Zhao GF, Huang LB
Connective tissue research 2023 Jul;64(4):323-336
Connective tissue research 2023 Jul;64(4):323-336
Activated KRAS reprograms neural progenitor cells to glioma stem cell‑like phenotype.
Qin Z, Liang W, Zhang Z, Li P, Wang T, Chen Q, Guo B, Zhong Y, Kang H, Wang L
International journal of oncology 2023 Jul;63(1)
International journal of oncology 2023 Jul;63(1)
Histone lysine demethylase 3B regulates autophagy via transcriptional regulation of GABARAPL1 in acute myeloid leukemia cells.
Song Y, Zhang J, Wang H, Wang H, Liu Y, Hu Z
International journal of oncology 2023 Jul;63(1)
International journal of oncology 2023 Jul;63(1)
Deficiency of S100 calcium binding protein A9 attenuates vascular dysfunction in aged mice.
Zhao B, Yu J, Luo Y, Xie M, Qu C, Shi Q, Wang X, Zhao X, Kong L, Zhao Y, Guo Y
Redox biology 2023 Jul;63:102721
Redox biology 2023 Jul;63:102721
A framework for individualized splice-switching oligonucleotide therapy.
Kim J, Woo S, de Gusmao CM, Zhao B, Chin DH, DiDonato RL, Nguyen MA, Nakayama T, Hu CA, Soucy A, Kuniholm A, Thornton JK, Riccardi O, Friedman DA, El Achkar CM, Dash Z, Cornelissen L, Donado C, Faour KNW, Bush LW, Suslovitch V, Lentucci C, Park PJ, Lee EA, Patterson A, Philippakis AA, Margus B, Berde CB, Yu TW
Nature 2023 Jul;619(7971):828-836
Nature 2023 Jul;619(7971):828-836
PLSCR1 is a cell-autonomous defence factor against SARS-CoV-2 infection.
Xu D, Jiang W, Wu L, Gaudet RG, Park ES, Su M, Cheppali SK, Cheemarla NR, Kumar P, Uchil PD, Grover JR, Foxman EF, Brown CM, Stansfeld PJ, Bewersdorf J, Mothes W, Karatekin E, Wilen CB, MacMicking JD
Nature 2023 Jul;619(7971):819-827
Nature 2023 Jul;619(7971):819-827
GDF11, a target of miR-32-5p, suppresses high-glucose-induced mitochondrial dysfunction and apoptosis in HK-2 cells through PI3K/AKT signaling activation.
Wang H, Zhang Y, Liu H, Li S
International urology and nephrology 2023 Jul;55(7):1767-1778
International urology and nephrology 2023 Jul;55(7):1767-1778
RNA-binding Protein QKI Inhibits Osteogenic Differentiation Via Suppressing Wnt Pathway.
Yan Z, Ruan B, Wang S, Du T, Shao X, Chen G, Wang L, Zhai D, Zhu S, Lu Z, Cao X
Archives of medical research 2023 Jul;54(5):102853
Archives of medical research 2023 Jul;54(5):102853
Protoporphyrin IX-loaded albumin nanoparticles reverse cancer chemoresistance by enhancing intracellular reactive oxygen species.
Xu X, Wang C, Guan W, Wang F, Li X, Yuan J, Xu G
Nanomedicine : nanotechnology, biology, and medicine 2023 Jul;51:102688
Nanomedicine : nanotechnology, biology, and medicine 2023 Jul;51:102688
Synergistic effect of elevated glucose levels with SARS-CoV-2 spike protein induced NOX-dependent ROS production in endothelial cells.
Zhang J, He L, Huang R, Alvarez JF, Yang DH, Sun Q, Wang F, Peng Z, Jiang N, Su L
Molecular biology reports 2023 Jul;50(7):6039-6047
Molecular biology reports 2023 Jul;50(7):6039-6047
STAT4, a potential predictor of prognosis, promotes CD8 T‑cell infiltration in ovarian serous carcinoma by inducing CCL5 secretion.
Wang W, Liu S, Lu F, Yang B, Zhuang X, Yin J, Chen G, Sun C
Oncology reports 2023 Jul;50(1)
Oncology reports 2023 Jul;50(1)
Metformin synergistically enhances the antitumour activity of Lenvatinib in hepatocellular carcinoma by altering AKT-FOXO3 signalling pathway.
Cheng Y, Zhan P, Lu J, Lu Y, Luo C, Cen X, Wang F, Xie C, Yin Z
Liver international : official journal of the International Association for the Study of the Liver 2023 Jul;43(7):1577-1592
Liver international : official journal of the International Association for the Study of the Liver 2023 Jul;43(7):1577-1592
Autophagy-related gene PXN as a prognostic marker: Promotion of ovarian cancer progression by suppressing the p110β/Vps34/Beclin1 pathway.
Wu Q, Cui Z, Jiang S, Xia H, Liu L, You Y, Sun Y
Cell biochemistry and function 2023 Jul;41(5):599-608
Cell biochemistry and function 2023 Jul;41(5):599-608
Circular forms of dedicator of cytokinesis 1 promotes breast cancer progression by derepressing never in mitosis related kinase 2 via sponging miR-128-3p.
Ni Z, Liu W, Pan G, Mao A, Liu J, Zhang Q, Li J, Liu L, Li H
Environmental toxicology 2023 Jul;38(7):1712-1722
Environmental toxicology 2023 Jul;38(7):1712-1722
Nucleolar protein treacle ribosome biogenesis factor 1 maintains gastric cancer cell proliferation by regulating R-loop associated DNA replication stress.
Nie X, Zhao C, Zhang Y, Huang W, Zhou Y, Liu H, Nie Y, Xie K, Jia L
Journal of gastroenterology and hepatology 2023 Jul;38(7):1170-1180
Journal of gastroenterology and hepatology 2023 Jul;38(7):1170-1180
The day-night differences in cognitive and anxiety-like behaviors of mice after chronic sleep restriction.
Zhai S, Yin MM, Sun HQ, Jiang XQ, Liu Y, Marshall C, Wu T, Xiao M
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Jul;37(7):e23034
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Jul;37(7):e23034
A mitochondria-targeting ROS-activated nanoprodrug for self-augmented antitumor oxidation therapy.
Zeng Z, Luo Y, Xu X, Shan T, Chen M, Huang Z, Huang Y, Zhao C
Journal of controlled release : official journal of the Controlled Release Society 2023 Jul;359:415-427
Journal of controlled release : official journal of the Controlled Release Society 2023 Jul;359:415-427
The deubiquitinase USP28 maintains the expression of the transcription factor MYCN and is essential in neuroblastoma cells.
Li J, Peng J, Wu L, Shen X, Zhen X, Zhang Y, Ma H, Xu Y, Xiong Q, Zhu Q, Zhang P
The Journal of biological chemistry 2023 Jul;299(7):104856
The Journal of biological chemistry 2023 Jul;299(7):104856
Porcine reproductive and respiratory syndrome virus infection inhibits NF-κB signaling pathway through cleavage of IKKβ by Nsp4.
Jiao S, Li C, Liu H, Xue M, Zhou Q, Zhang L, Liu X, Feng C, Ye G, Liu J, Li J, Huang L, Xiong T, Zhang Z, Weng C
Veterinary microbiology 2023 Jul;282:109767
Veterinary microbiology 2023 Jul;282:109767
Combination therapy with BMSCs‑exosomes and porous tantalum for the repair of femur supracondylar defects.
Yang F, Wu M, Chen H, Ma S, Liu J, Li C, Li Y, Yang J, Liu B, Zhao D
Molecular medicine reports 2023 Jul;28(1)
Molecular medicine reports 2023 Jul;28(1)
Transmembrane nuclease NUMEN/ENDOD1 regulates DNA repair pathway choice at the nuclear periphery.
Chen B, Ge T, Jian M, Chen L, Fang Z, He Z, Huang C, An Y, Yin S, Xiong Y, Zhang J, Li R, Ye M, Li Y, Liu F, Ma W, Songyang Z
Nature cell biology 2023 Jul;25(7):1004-1016
Nature cell biology 2023 Jul;25(7):1004-1016
Matrix metalloproteinases are key targets of acupuncture in the treatment of ulcerative colitis.
Zhang RB, Dong LC, Huang Q, Shen Y, Li HY, Yu SG, Wu QF
Experimental biology and medicine (Maywood, N.J.) 2023 Jul;248(14):1229-1241
Experimental biology and medicine (Maywood, N.J.) 2023 Jul;248(14):1229-1241
The inhibitory effect of vitamin D on myocardial homocysteine levels involves activation of Nrf2-mediated methionine synthase.
Sun X, Liu N, Sun C, Xu Y, Ding D, Kong J
The Journal of steroid biochemistry and molecular biology 2023 Jul;231:106303
The Journal of steroid biochemistry and molecular biology 2023 Jul;231:106303
m6A Modification Mediates Exosomal LINC00657 to Trigger Breast Cancer Progression Via Inducing Macrophage M2 Polarization.
Chen J, Zhou Y, Wu M, Yuan Y, Wu W
Clinical breast cancer 2023 Jul;23(5):546-560
Clinical breast cancer 2023 Jul;23(5):546-560
Islet amyloid polypeptide triggers α-synuclein pathology in Parkinson's disease.
Meng L, Li Y, Liu C, Zhang G, Chen J, Xiong M, Pan L, Zhang X, Chen G, Xiong J, Liu C, Xu X, Bu L, Zhang Z, Zhang Z
Progress in neurobiology 2023 Jul;226:102462
Progress in neurobiology 2023 Jul;226:102462
Anisomycin inhibits Coxsackievirus B replication by promoting the lysosomal degradation of eEF1A1.
Shao E, Zhao S, Dong Y, Wang Y, Fei Y, Li S, Wang L, Bashir T, Luan T, Lin L, Wang Y, Zhao W, Zhong Z
Antiviral research 2023 Jul;215:105621
Antiviral research 2023 Jul;215:105621
Harringtonine: A more effective antagonist for Omicron variant.
Hu S, Wang N, Chen S, Zhang H, Wang C, Ma W, Zhang X, Wu Y, Lv Y, Xue Z, Bai H, Ge S, He H, Lu W, Zhang T, Ding Y, Liu R, Han S, Zhan Y, Zhan G, Guo Z, Zhang Y, Lu J, Gao J, Jia Q, Wang Y, Wang H, Lu S, Jin T, Chiu S, He L
Biochemical pharmacology 2023 Jul;213:115617
Biochemical pharmacology 2023 Jul;213:115617
SIRT3-mediated autophagy contributes to ferroptosis-induced anticancer by inducing the formation of BECN1-SLC7A11 complex.
Huang P, Zhao H, Pan X, Li J, Pan W, Dai H, Wang J, Xia C, Liu F
Biochemical pharmacology 2023 Jul;213:115592
Biochemical pharmacology 2023 Jul;213:115592
Neotuberostemonine and tuberostemonine ameliorate pulmonary fibrosis through suppressing TGF-β and SDF-1 secreted by macrophages and fibroblasts via the PI3K-dependent AKT and ERK pathways.
Fu S, Song X, Hu Y, Zhu Q, Lv X, Tang X, Zhang M
Chinese journal of natural medicines 2023 Jul;21(7):527-539
Chinese journal of natural medicines 2023 Jul;21(7):527-539
Dexmedetomidine Suppresses Glutamate-Stimulated Neuronal Injury Via MicroRNA-433/Janus Kinase 2/Signal Transducer and Activator of Transcription 3 Pathway.
Zhao L, Huang J, Wu Z, Fu G
Iranian journal of biotechnology 2023 Jul;21(3):e3214
Iranian journal of biotechnology 2023 Jul;21(3):e3214
Targeting ABCB6 with nitidine chloride inhibits PI3K/AKT signaling pathway to promote ferroptosis in multiple myeloma.
Yin Z, Lv Y, Deng L, Li G, Ou R, Chen L, Zhu Y, Zhong Q, Liu Z, Huang J, Wu H, Zhang Q, Fei J, Liu S
Free radical biology & medicine 2023 Jul;203:86-101
Free radical biology & medicine 2023 Jul;203:86-101
UBQLN1 deficiency mediates telomere shortening and IPF through interacting with RPA1.
Zhou H, Xie C, Xie Y, He Y, Chen Y, Zhang C, Zhang Y, Zhao Y, Liu H
PLoS genetics 2023 Jul;19(7):e1010856
PLoS genetics 2023 Jul;19(7):e1010856
hUMSCs Transplantation Regulates AMPK/NR4A1 Signaling Axis to Inhibit Ovarian Fibrosis in POI Rats.
Cui L, Bao H, Zhu W, Tang Y, Luo Q, Si Y, Fu Q, Jiang Z
Stem cell reviews and reports 2023 Jul;19(5):1449-1465
Stem cell reviews and reports 2023 Jul;19(5):1449-1465
Upregulation of CDGSH iron sulfur domain 2 attenuates cerebral ischemia/reperfusion injury.
Hu M, Huang J, Chen L, Sun XR, Yao ZM, Tong XH, Jin WJ, Zhang YX, Dong SY
Neural regeneration research 2023 Jul;18(7):1512-1520
Neural regeneration research 2023 Jul;18(7):1512-1520
Combined exposure to lead and high-fat diet induced neuronal deficits in rats: Anti-neuroinflammatory role of SIRT1.
Liu M, Liu R, Yang M, Ba Y, Deng Q, Zhang Y, Han L, Gao L, Huang H
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2023 Jul;177:113857
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2023 Jul;177:113857
The bound polyphenols of foxtail millet (Setaria italica) inner shell inhibit breast cancer by promoting lipid accumulation-induced autophagic death.
Zhang LC, Liu YN, La XQ, Li ST, Wen LN, Liu T, Li HQ, Li AP, Wu H, Wu CX, Li ZY
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2023 Jul;177:113855
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2023 Jul;177:113855
Integration of proteomics and network toxicology reveals the mechanism of mercury chloride induced hepatotoxicity, in mice and HepG2 cells.
Cao X, Mao K, Zhang Y, Yang M, Liu H, Wang X, Hao L
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2023 Jul;177:113820
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2023 Jul;177:113820
Liensinine, a alkaloid from lotus plumule, mitigates lipopolysaccharide-induced sepsis-associated encephalopathy through modulation of nuclear factor erythroid 2-related factor-mediated inflammatory biomarkers and mitochondria apoptosis.
Wang G, Sun Y, Yang Q, Dai D, Zhang L, Fan H, Zhang W, Dong J, Zhao P
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2023 Jul;177:113813
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2023 Jul;177:113813
Single-cell sequencing analysis reveals development and differentiation trajectory of Schwann cells manipulated by M. leprae.
Ma S, Mi Z, Wang Z, Sun L, Liu T, Shi P, Wang C, Xue X, Chen W, Wang Z, Yu Y, Zhang Y, Bao F, Wang N, Wang H, Xia Q, Liu H, Sun Y, Zhang F
PLoS neglected tropical diseases 2023 Jul;17(7):e0011477
PLoS neglected tropical diseases 2023 Jul;17(7):e0011477
Astragalus polysaccharide ameliorated complex factor-induced chronic fatigue syndrome by modulating the gut microbiota and metabolites in mice.
Wei X, Xin J, Chen W, Wang J, Lv Y, Wei Y, Li Z, Ding Q, Shen Y, Xu X, Zhang X, Zhang W, Zu X
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Jul;163:114862
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Jul;163:114862
Xanthotoxin, a novel inducer of platelet formation, promotes thrombocytopoiesis via IL-1R1 and MEK/ERK signaling.
Lai J, Li Y, Ran M, Huang Q, Huang F, Zhu L, Wu Y, Zou W, Xie X, Tang Y, Yang F, Wu A, Ge G, Wu J
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Jul;163:114811
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Jul;163:114811
Nobiletin alleviates myocardial ischemia-reperfusion injury via ferroptosis in rats with type-2 diabetes mellitus.
Huang Q, Tian L, Zhang Y, Qiu Z, Lei S, Xia ZY
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Jul;163:114795
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Jul;163:114795
Vitamin B12 alleviates myocardial ischemia/reperfusion injury via the SIRT3/AMPK signaling pathway.
Qin Y, Shi Y, Yu Q, Yang S, Wang Y, Dai X, Li G, Cheng Z
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Jul;163:114761
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Jul;163:114761
Analysis and Validation of TMED3 correlates with poor prognosis and tumor immune infiltration of glioma.
Liao G, Zhang M, Wang C
Journal of cancer research and clinical oncology 2023 Jul;149(7):3485-3494
Journal of cancer research and clinical oncology 2023 Jul;149(7):3485-3494
Extracellular vesicles derived from hypoxic HTR-8/SVneo trophoblast inhibit endothelial cell functions through the miR-150-3p /CHPF pathway.
Sha M, Zhang S, Beejadhursing R, Sun Y, Qin Y, Chen S, Li W
Placenta 2023 Jul;138:21-32
Placenta 2023 Jul;138:21-32
CRIP1 supports the growth and migration of AML-M5 subtype cells by activating Wnt/β-catenin pathway.
Deng X, Zeng Y, Qiu X, Zhong M, Xiong X, Luo M, Zhang J, Chen X
Leukemia research 2023 Jul;130:107312
Leukemia research 2023 Jul;130:107312
RIPK3-MLKL necroptotic signalling amplifies STING pathway and exacerbates lethal sepsis.
Zhang X, Wu J, Liu Q, Li X, Yang Y, Wu L, Wu X, Zhao Y, Ren J
Clinical and translational medicine 2023 Jul;13(7):e1334
Clinical and translational medicine 2023 Jul;13(7):e1334
Dissecting the effect of ileal faecal diversion on the intestine using single-cell sequencing.
Ma H, Li X, Pan Y, Wang L, Han B, Xie H, Zheng H, Jiang E, Chen J, Li Y, Ji G, Qiu Y, Xiao W
Clinical and translational medicine 2023 Jul;13(7):e1321
Clinical and translational medicine 2023 Jul;13(7):e1321
Single-cell landscape analysis reveals systematic senescence in mammalian Down syndrome.
Chen Y, Xiao Y, Zhang Y, Wang R, Wang F, Gao H, Liu Y, Zhang R, Sun H, Zhou Z, Wang S, Chen K, Sun Y, Tu M, Li J, Luo Q, Wu Y, Zhu L, Huang Y, Sun X, Guo G, Zhang D
Clinical and translational medicine 2023 Jul;13(7):e1310
Clinical and translational medicine 2023 Jul;13(7):e1310
Dipeptidyl peptidase 3 is essential for maintaining osteoblastic differentiation under a high-glucose environment by inhibiting apoptosis, oxidative stress and inflammation through the modulation of the Keap1-Nrf2 pathway.
Li X, Yu X, He S, Li J
International immunopharmacology 2023 Jul;120:110404
International immunopharmacology 2023 Jul;120:110404
Aloperine alleviates lipopolysaccharide-induced acute lung injury by inhibiting NLRP3 inflammasome activation.
Zeng J, Liu J, Huang JH, Fu SP, Wang XY, Xi C, Cui YR, Qu F
International immunopharmacology 2023 Jul;120:110142
International immunopharmacology 2023 Jul;120:110142
l-Arginine-Modified CoWO(4) /FeWO(4) S-Scheme Heterojunction Enhances Ferroptosis against Solid Tumor.
Yang Z, Yang C, Yang D, Zhang Y, Yang Q, Qu F, Guo W
Advanced healthcare materials 2023 Jul;12(18):e2203092
Advanced healthcare materials 2023 Jul;12(18):e2203092
Inhibition of FGFR3 upregulates MHC-I and PD-L1 via TLR3/NF-kB pathway in muscle-invasive bladder cancer.
Wu W, Chen L, Jia G, Tang Q, Han B, Xia S, Jiang Q, Liu H
Cancer medicine 2023 Jul;12(14):15676-15690
Cancer medicine 2023 Jul;12(14):15676-15690
COLEC10 Induces Endoplasmic Reticulum Stress by Occupying GRP78 and Inhibits Hepatocellular Carcinoma.
Cai MN, Chen DM, Xiao LX, Li SS, Liao CH, Li J, Huang ZX, Wang JL, Gu YR, Gu L, Huang YH, Lian YF
Laboratory investigation; a journal of technical methods and pathology 2023 Jul;103(7):100130
Laboratory investigation; a journal of technical methods and pathology 2023 Jul;103(7):100130
RNA-seq analysis reveals candidate genes associated with proliferation, invasion, and migration in BCL11A knockdown B-NHL cell lines.
Yin J, Xie X, Quan Y, Wang Z, Liu S, Su Q, Che F, Wang L
Annals of hematology 2023 Jul;102(7):1845-1856
Annals of hematology 2023 Jul;102(7):1845-1856
Ultrasound Responsive Nanovaccine Armed with Engineered Cancer Cell Membrane and RNA to Prevent Foreseeable Metastasis.
Sun W, Ji P, Zhou T, Li Z, Xing C, Zhang L, Wei M, Yang G, Yuan L
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Jul;10(19):e2301107
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Jul;10(19):e2301107
Alleviation of Limosilactobacillus reuteri in polycystic ovary syndrome protects against circadian dysrhythmia-induced dyslipidemia via capric acid and GALR1 signaling.
Li S, Zhai J, Chu W, Geng X, Wang D, Jiao L, Lu G, Chan WY, Sun K, Sun Y, Chen ZJ, Du Y
NPJ biofilms and microbiomes 2023 Jul 8;9(1):47
NPJ biofilms and microbiomes 2023 Jul 8;9(1):47
Targeting macrophagic PIM-1 alleviates osteoarthritis by inhibiting NLRP3 inflammasome activation via suppressing mitochondrial ROS/Cl(-) efflux signaling pathway.
Zhang Z, Xie S, Qian J, Gao F, Jin W, Wang L, Yan L, Chen H, Yao W, Li M, Wang X, Zhu L
Journal of translational medicine 2023 Jul 8;21(1):452
Journal of translational medicine 2023 Jul 8;21(1):452
The Extract of Scutellaria baicalensis Attenuates the Pattern Recognition Receptor Pathway Activation Induced by Influenza A Virus in Macrophages.
Yang M, Ma L, Su R, Guo R, Zhou N, Liu M, Wu J, Wang Y, Hao Y
Viruses 2023 Jul 8;15(7)
Viruses 2023 Jul 8;15(7)
VDR alleviates endothelial cell injury in arteriovenous fistula through inhibition of P66Shc-mediated mitochondrial ROS.
Han YC, Liu YT, Zhang H, Xu Y, Liu J, Chen H, Song N, Qin DL, Yang S
Scientific reports 2023 Jul 8;13(1):11088
Scientific reports 2023 Jul 8;13(1):11088
Ferrostatin-1 alleviates the damage of C2C12 myoblast and mouse pelvic floor muscle induced by mechanical trauma.
He Y, Huang G, Hong S, Zuo X, Zhao Z, Hong L
Cell death discovery 2023 Jul 7;9(1):232
Cell death discovery 2023 Jul 7;9(1):232
Aberrant mechanical loading induces annulus fibrosus cells apoptosis in intervertebral disc degeneration via mechanosensitive ion channel Piezo1.
Liu C, Gao X, Lou J, Li H, Chen Y, Chen M, Zhang Y, Hu Z, Chang X, Luo M, Zhai Y, Li C
Arthritis research & therapy 2023 Jul 7;25(1):117
Arthritis research & therapy 2023 Jul 7;25(1):117
Proximity Proteomics and Biochemical Analysis Reveal a Noncanonical Function for UFM1-Specific Protease 1 in the p62 Body Formation.
Wang X, Cao L, Jiang H, Zhou L, Hu Z, Xu G
Journal of proteome research 2023 Jul 7;22(7):2352-2363
Journal of proteome research 2023 Jul 7;22(7):2352-2363
Higher expression of pseudouridine synthase 7 promotes non-small cell lung cancer progression and suggests a poor prognosis.
Zhang G, Zhu Y, Tan Y, Chen B, Shan S, Zhang G, Lu J
Journal of cardiothoracic surgery 2023 Jul 7;18(1):222
Journal of cardiothoracic surgery 2023 Jul 7;18(1):222
PARP1 negatively regulates transcription of BLM through its interaction with HSP90AB1 in prostate cancer.
Huang M, Chen L, Guo Y, Ruan Y, Xu H
Journal of translational medicine 2023 Jul 6;21(1):445
Journal of translational medicine 2023 Jul 6;21(1):445
Cooperative sensing of mitochondrial DNA by ZBP1 and cGAS promotes cardiotoxicity.
Lei Y, VanPortfliet JJ, Chen YF, Bryant JD, Li Y, Fails D, Torres-Odio S, Ragan KB, Deng J, Mohan A, Wang B, Brahms ON, Yates SD, Spencer M, Tong CW, Bosenberg MW, West LC, Shadel GS, Shutt TE, Upton JW, Li P, West AP
Cell 2023 Jul 6;186(14):3013-3032.e22
Cell 2023 Jul 6;186(14):3013-3032.e22
The translational landscape of human vascular smooth muscle cells identifies novel short open reading frame-encoded peptide regulators for phenotype alteration.
Li K, Li B, Zhang D, Du T, Zhou H, Dai G, Yan Y, Gao N, Zhuang X, Liao X, Liu C, Dong Y, Chen D, Qu LH, Ou J, Yang JH, Huang ZP
Cardiovascular research 2023 Jul 6;119(8):1763-1779
Cardiovascular research 2023 Jul 6;119(8):1763-1779
The protective effects of sophocarpine on sepsis-induced cardiomyopathy.
Fu Y, Zhang HJ, Zhou W, Lai ZQ, Dong YF
European journal of pharmacology 2023 Jul 5;950:175745
European journal of pharmacology 2023 Jul 5;950:175745
5-Azacytidine promotes HCC cell metastasis by up-regulating RDH16 expression.
Le L, Qipeng W, Chunmeng M, Hasnat M, Luyong Z, Zhenzhou J, Qinwei Y
European journal of pharmacology 2023 Jul 5;950:175736
European journal of pharmacology 2023 Jul 5;950:175736
SGLT2 inhibitor dapagliflozin alleviates intramyocardial hemorrhage and adverse ventricular remodeling via suppressing hepcidin in myocardial ischemia-reperfusion injury.
Chen R, Zhang Y, Zhang H, Zhou H, Tong W, Wu Y, Ma M, Chen Y
European journal of pharmacology 2023 Jul 5;950:175729
European journal of pharmacology 2023 Jul 5;950:175729
Jujuboside A ameliorates cognitive deficiency in delirium through promoting hippocampal E4BP4 in mice.
Du J, Zhang F, Chen M, Xiao Y, Zhang L, Dong L, Dong D, Wu B
The Journal of pharmacy and pharmacology 2023 Jul 5;75(7):886-897
The Journal of pharmacy and pharmacology 2023 Jul 5;75(7):886-897
BMP2 induces osteogenic differentiation through ACKR3 in mesenchymal stem cells.
Liu J, Yao XT, Feng XL, Bai XZ
Biochemical and biophysical research communications 2023 Jul 5;664:59-68
Biochemical and biophysical research communications 2023 Jul 5;664:59-68
P2X7 receptor-mediated depression-like reactions arising in the mouse medial prefrontal cortex.
Ren WJ, Zhao YF, Li J, Rubini P, Yuan ZQ, Tang Y, Illes P
Cerebral cortex (New York, N.Y. : 1991) 2023 Jul 5;33(14):8858-8875
Cerebral cortex (New York, N.Y. : 1991) 2023 Jul 5;33(14):8858-8875
GBAP1 functions as a tumor promotor in hepatocellular carcinoma via the PI3K/AKT pathway.
Chen R, Zhao M, An Y, Liu D, Tang Q
BMC cancer 2023 Jul 5;23(1):628
BMC cancer 2023 Jul 5;23(1):628
A novel polypeptide CAPG-171aa encoded by circCAPG plays a critical role in triple-negative breast cancer.
Song R, Guo P, Ren X, Zhou L, Li P, Rahman NA, Wołczyński S, Li X, Zhang Y, Liu M, Liu J, Li X
Molecular cancer 2023 Jul 5;22(1):104
Molecular cancer 2023 Jul 5;22(1):104
Downregulation of BASP1 Promotes Temozolomide Resistance in Gliomas via Epigenetic Activation of the FBXO32/NF-κB/MGMT Axis.
Liao X, Li Z, Zheng H, Qian W, Zhang S, Chen S, Li X, Tang M, Xu Y, Yu R, Li M, Song L, Li J
Molecular cancer research : MCR 2023 Jul 5;21(7):648-663
Molecular cancer research : MCR 2023 Jul 5;21(7):648-663
The role of TOP2A in immunotherapy and vasculogenic mimicry in non-small cell lung cancer and its potential mechanism.
Wu J, Zhang L, Li W, Wang L, Jia Q, Shi F, Li K, Liao L, Shi Y, Wu S
Scientific reports 2023 Jul 5;13(1):10906
Scientific reports 2023 Jul 5;13(1):10906
IL-33/ST2 axis of human amnion fibroblasts participates in inflammatory reactions at parturition.
Lei WJ, Zhang F, Lin YK, Li MD, Pan F, Sun K, Wang WS
Molecular medicine (Cambridge, Mass.) 2023 Jul 4;29(1):88
Molecular medicine (Cambridge, Mass.) 2023 Jul 4;29(1):88
LncRNA LZTS1-AS1 induces proliferation, metastasis and inhibits autophagy of pancreatic cancer cells through the miR-532 /TWIST1 signaling pathway.
Wu H, Li A, Zheng Q, Gu J, Zhou W
Cancer cell international 2023 Jul 4;23(1):130
Cancer cell international 2023 Jul 4;23(1):130
Macrophage lineage cells-derived migrasomes activate complement-dependent blood-brain barrier damage in cerebral amyloid angiopathy mouse model.
Hu M, Li T, Ma X, Liu S, Li C, Huang Z, Lin Y, Wu R, Wang S, Lu D, Lu T, Men X, Shen S, Huang H, Liu Y, Song K, Jian B, Jiang Y, Qiu W, Liu Q, Lu Z, Cai W
Nature communications 2023 Jul 4;14(1):3945
Nature communications 2023 Jul 4;14(1):3945
MAT as a promising therapeutic strategy against triple-negative breast cancer via inhibiting PI3K/AKT pathway.
Wei S, Zhang Y, Ma X, Yao Y, Zhou Q, Zhang W, Zhou C, Zhuang J
Scientific reports 2023 Jul 31;13(1):12351
Scientific reports 2023 Jul 31;13(1):12351
Tanshinone I specifically suppresses NLRP3 inflammasome activation by disrupting the association of NLRP3 and ASC.
Zhao J, Liu H, Hong Z, Luo W, Mu W, Hou X, Xu G, Fang Z, Ren L, Liu T, Wen J, Shi W, Wei Z, Yang Y, Zou W, Zhao J, Xiao X, Bai Z, Zhan X
Molecular medicine (Cambridge, Mass.) 2023 Jul 3;29(1):84
Molecular medicine (Cambridge, Mass.) 2023 Jul 3;29(1):84
Disruption of RCAN1.4 expression mediated by YY1/HDAC2 modulates chronic renal allograft interstitial fibrosis.
Zhang J, Zhang Y, Feng D, Zhou H, Gui Z, Zheng M, Hang Z, Gu M, Tan R
Cell death discovery 2023 Jul 28;9(1):271
Cell death discovery 2023 Jul 28;9(1):271
Modified Podophyllotoxin Phenoxyacetamide Phenylacetate Derivatives: Tubulin/AKT1 Dual-Targeting and Potential Anticancer Agents for Human NSCLC.
Lin H, Ai D, Liu Q, Wang X, Gao J, Chen Q, Ruan L, Tao Y, Gao J, Wang L
Journal of natural products 2023 Jul 28;86(7):1844-1854
Journal of natural products 2023 Jul 28;86(7):1844-1854
Intestinal Cckbr-specific knockout mouse as a novel model of salt-sensitive hypertension via sodium over-absorption.
Zhang QY, Guo Y, Jiang XL, Liu X, Zhao SG, Zhou XL, Yang ZW
Journal of geriatric cardiology : JGC 2023 Jul 28;20(7):538-547
Journal of geriatric cardiology : JGC 2023 Jul 28;20(7):538-547
Reduced NR2F2 Expression in the Host Response to Infectious Bursal Disease Virus Infection Suppressed Viral Replication by Enhancing Type I Interferon Expression by Targeting SOCS5.
You G, Li W, Wang Y, Cao H, Li X, Gao L, Zheng SJ
Journal of virology 2023 Jul 27;97(7):e0066423
Journal of virology 2023 Jul 27;97(7):e0066423
Coreceptor AXL Facilitates African Swine Fever Virus Entry via Apoptotic Mimicry.
Chen X, Zheng J, Li T, Liu C, Bao M, Wang X, Li X, Li J, Huang L, Zhang Z, Weng C
Journal of virology 2023 Jul 27;97(7):e0061623
Journal of virology 2023 Jul 27;97(7):e0061623
USP18 overexpression protects against spinal cord ischemia/reperfusion injury via regulating autophagy.
Yuan L, Xu J, Qin F, Yi X, Zhong Z, Gu X, Gong G
Neuroscience letters 2023 Jul 27;810:137359
Neuroscience letters 2023 Jul 27;810:137359
Interaction between neutrophil extracellular traps and cardiomyocytes contributes to atrial fibrillation progression.
He L, Liu R, Yue H, Zhang X, Pan X, Sun Y, Shi J, Zhu G, Qin C, Guo Y
Signal transduction and targeted therapy 2023 Jul 26;8(1):279
Signal transduction and targeted therapy 2023 Jul 26;8(1):279
Injectable hydrogel made from antler mesenchyme matrix for regenerative wound healing via creating a fetal-like niche.
Zhang GK, Ren J, Li JP, Wang DX, Wang SN, Shi LY, Li CY
World journal of stem cells 2023 Jul 26;15(7):768-780
World journal of stem cells 2023 Jul 26;15(7):768-780
Identification of TGF-β-related genes in cardiac hypertrophy and heart failure based on single cell RNA sequencing.
Huang K, Wu H, Xu X, Wu L, Li Q, Han L
Aging 2023 Jul 26;15(14):7187-7218
Aging 2023 Jul 26;15(14):7187-7218
ALKBH5 causes retinal pigment epithelium anomalies and choroidal neovascularization in age-related macular degeneration via the AKT/mTOR pathway.
Sun RX, Zhu HJ, Zhang YR, Wang JN, Wang Y, Cao QC, Ji JD, Jiang C, Yuan ST, Chen X, Liu QH
Cell reports 2023 Jul 25;42(7):112779
Cell reports 2023 Jul 25;42(7):112779
A MOF-Based Potent Ferroptosis Inducer for Enhanced Radiotherapy of Triple Negative Breast Cancer.
Zeng L, Ding S, Cao Y, Li C, Zhao B, Ma Z, Zhou J, Hu Y, Zhang X, Yang Y, Duan G, Bian XW, Tian G
ACS nano 2023 Jul 25;17(14):13195-13210
ACS nano 2023 Jul 25;17(14):13195-13210
Metastasis-related gene signature associates with immunity and predicts prognosis accurately in patients with osteosarcoma.
Qin S, Li L, Liu D
Aging 2023 Jul 25;15(14):7219-7236
Aging 2023 Jul 25;15(14):7219-7236
Membrane stretch as the mechanism of activation of PIEZO1 ion channels in chondrocytes.
Savadipour A, Nims RJ, Rashidi N, Garcia-Castorena JM, Tang R, Marushack GK, Oswald SJ, Liedtke WB, Guilak F
Proceedings of the National Academy of Sciences of the United States of America 2023 Jul 25;120(30):e2221958120
Proceedings of the National Academy of Sciences of the United States of America 2023 Jul 25;120(30):e2221958120
Kaempferol inhibits non-homologous end joining repair via regulating Ku80 stability in glioma cancer.
Chen M, Zhao E, Li M, Xu M, Hao S, Gao Y, Wu X, Li X, Yu Y, Yu Z, Yin Y
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Jul 25;116:154876
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Jul 25;116:154876
CD44 Is Associated with Poor Prognosis of ccRCC and Facilitates ccRCC Cell Migration and Invasion through HAS1/MMP9.
Du T, Wu Z, Wu Y, Liu Y, Song Y, Ma L
Biomedicines 2023 Jul 24;11(7)
Biomedicines 2023 Jul 24;11(7)
SIRT3 ameliorates diabetes-associated cognitive dysfunction via regulating mitochondria-associated ER membranes.
Chang Y, Wang C, Zhu J, Zheng S, Sun S, Wu Y, Jiang X, Li L, Ma R, Li G
Journal of translational medicine 2023 Jul 22;21(1):494
Journal of translational medicine 2023 Jul 22;21(1):494
AAV-GRN partially corrects motor deficits and ALS/FTLD-related pathology in Tmem106b(-/-)Grn(-/-) mice.
Feng T, Minevich G, Liu P, Qin HX, Wozniak G, Pham J, Pham K, Korgaonkar A, Kurnellas M, Defranoux NA, Long H, Mitra A, Hu F
iScience 2023 Jul 21;26(7):107247
iScience 2023 Jul 21;26(7):107247
A proximity labeling strategy enables proteomic analysis of inter-organelle membrane contacts.
Zhou M, Kong B, Zhang X, Xiao K, Lu J, Li W, Li M, Li Z, Ji W, Hou J, Xu T
iScience 2023 Jul 21;26(7):107159
iScience 2023 Jul 21;26(7):107159
Suppression of TREX1 deficiency-induced cellular senescence and interferonopathies by inhibition of DNA damage response.
Du H, Xiao N, Zhang S, Zhou X, Zhang Y, Lu Z, Fu Y, Huang M, Xu S, Chen Q
iScience 2023 Jul 21;26(7):107090
iScience 2023 Jul 21;26(7):107090
Establishing SARS-CoV-2 membrane protein-specific antibodies as a valuable serological target via high-content microscopy.
Williams DM, Hornsby HR, Shehata OM, Brown R, Gallis M, Meardon N, Newman TAH, Plowright M, Zafred D, Shun-Shion ASM, Hodder AJ, Bliss D, Metcalfe A, Edgar JR, Gordon DE, Sayers JR, Nicklin MJ, Carroll M, PITCH Consortium, Collini PJ, Brown S, de Silva TI, Peden AA
iScience 2023 Jul 21;26(7):107056
iScience 2023 Jul 21;26(7):107056
Uterine-specific Ezh2 deletion enhances stromal cell senescence and impairs placentation, resulting in pregnancy loss.
Sirohi VK, Medrano TI, Kannan A, Bagchi IC, Cooke PS
iScience 2023 Jul 21;26(7):107028
iScience 2023 Jul 21;26(7):107028
Acetylation halts missense mutant p53 aggregation and rescues tumor suppression in non-small cell lung cancers.
Xu D, Qian W, Yang Z, Zhang Z, Sun P, Wan Q, Yin Y, Hu Y, Gong L, Zhang B, Yang X, Pu Z, Lu P, Zou J
iScience 2023 Jul 21;26(7):107003
iScience 2023 Jul 21;26(7):107003
Esaxerenone Inhibits Renal Angiogenesis and Endothelial-Mesenchymal Transition via the VEGFA and TGF-β1 Pathways in Aldosterone-Infused Mice.
Gao X, Chang J, Chang Y, Fan L, Liu Z, Zhang C, Shimosawa T, Yang F, Xu Q
International journal of molecular sciences 2023 Jul 21;24(14)
International journal of molecular sciences 2023 Jul 21;24(14)
JUN-induced super-enhancer RNA forms R-loop to promote nasopharyngeal carcinoma metastasis.
Jia Q, Tan Y, Li Y, Wu Y, Wang J, Tang F
Cell death & disease 2023 Jul 21;14(7):459
Cell death & disease 2023 Jul 21;14(7):459
ZIC2 induces pro-tumor macrophage polarization in nasopharyngeal carcinoma by activating the JUNB/MCSF axis.
Liu Q, Yang T, Zhang Y, Hu ZD, Liu YM, Luo YL, Liu SX, Zhang H, Zhong Q
Cell death & disease 2023 Jul 21;14(7):455
Cell death & disease 2023 Jul 21;14(7):455
Integrative CRISPR Activation and Small Molecule Inhibitor Screening for lncRNA Mediating BRAF Inhibitor Resistance in Melanoma.
Shamloo S, Kloetgen A, Petroulia S, Hockemeyer K, Sievers S, Tsirigos A, Aifantis I, Imig J
Biomedicines 2023 Jul 21;11(7)
Biomedicines 2023 Jul 21;11(7)
[MiR-30e-5p overexpression promotes proliferation and migration of colorectal cancer cells by activating the CXCL12 axis via downregulating PTEN].
Wei K, Shi J, Xiao Y, Wang W, Yang Q, Chen C
Nan fang yi ke da xue xue bao = Journal of Southern Medical University 2023 Jul 20;43(7):1081-1092
Nan fang yi ke da xue xue bao = Journal of Southern Medical University 2023 Jul 20;43(7):1081-1092
QKI shuttles internal m(7)G-modified transcripts into stress granules and modulates mRNA metabolism.
Zhao Z, Qing Y, Dong L, Han L, Wu D, Li Y, Li W, Xue J, Zhou K, Sun M, Tan B, Chen Z, Shen C, Gao L, Small A, Wang K, Leung K, Zhang Z, Qin X, Deng X, Xia Q, Su R, Chen J
Cell 2023 Jul 20;186(15):3208-3226.e27
Cell 2023 Jul 20;186(15):3208-3226.e27
Atractylenolide III Ameliorates Bile Duct Ligation-Induced Liver Fibrosis by Inhibiting the PI3K/AKT Pathway and Regulating Glutamine Metabolism.
Wang Y, Shi K, Tu J, Ke C, Chen N, Wang B, Liu Y, Zhou Z
Molecules (Basel, Switzerland) 2023 Jul 19;28(14)
Molecules (Basel, Switzerland) 2023 Jul 19;28(14)
Lnc-LRRTM4 promotes proliferation, metastasis and EMT of colorectal cancer through activating LRRTM4 transcription.
Zhang J, Meng X, Zhou Y, Jiang Z, Chen H, Meng Z, Zhang Q, Chen W
Cancer cell international 2023 Jul 19;23(1):142
Cancer cell international 2023 Jul 19;23(1):142
Integrative analysis of the ST6GALNAC family identifies GATA2-upregulated ST6GALNAC5 as an adverse prognostic biomarker promoting prostate cancer cell invasion.
Li M, Ma Z, Zhang Y, Feng H, Li Y, Sang W, Zhu R, Huang R, Yan J
Cancer cell international 2023 Jul 19;23(1):141
Cancer cell international 2023 Jul 19;23(1):141
Comparative transcriptome profiling of Eimeria tenella in various developmental stages and functional analysis of an ApiAP2 transcription factor exclusively expressed during sporogony.
Chen L, Tang X, Sun P, Hu D, Zhang Y, Wang C, Chen J, Liu J, Gao Y, Hao Z, Zhang N, Chen W, Xie F, Suo X, Liu X
Parasites & vectors 2023 Jul 19;16(1):241
Parasites & vectors 2023 Jul 19;16(1):241
Two-in-One Polymeric NO-Donor Prodrugs Mediate Precision and Synergistic Prostate Cancer Treatment.
Zhao B, Wan Y, Zhou X, Zhang J, Chen J, Yang J, Liu Y, Chen W, Zhong Y, Qian H
ACS applied materials & interfaces 2023 Jul 19;15(28):33309-33321
ACS applied materials & interfaces 2023 Jul 19;15(28):33309-33321
NUMA1 modulates apoptosis of esophageal squamous cell carcinoma cells through regulating ASK1-JNK signaling pathway.
Yin S, Zhao S, Li J, Liu K, Ma X, Zhang Z, Wang R, Tian J, Liu F, Song Y, Song M, Zhao R, Yang R, Lee MH, Dong Z
Cellular and molecular life sciences : CMLS 2023 Jul 18;80(8):211
Cellular and molecular life sciences : CMLS 2023 Jul 18;80(8):211
Bifidobacterium adolescentis induces Decorin(+) macrophages via TLR2 to suppress colorectal carcinogenesis.
Lin Y, Fan L, Qi Y, Xu C, Jia D, Jiang Y, Chen S, Wang L
Journal of experimental & clinical cancer research : CR 2023 Jul 18;42(1):172
Journal of experimental & clinical cancer research : CR 2023 Jul 18;42(1):172
Neuroprotective effect of a medium-chain triglyceride ketogenic diet on MPTP-induced Parkinson's disease mice: a combination of transcriptomics and metabolomics in the substantia nigra and fecal microbiome.
Zhang W, Chen S, Huang X, Tong H, Niu H, Lu L
Cell death discovery 2023 Jul 17;9(1):251
Cell death discovery 2023 Jul 17;9(1):251
Ablation of the gut microbiota alleviates high-methionine diet-induced hyperhomocysteinemia and glucose intolerance in mice.
Li W, Jia Y, Gong Z, Dong Z, Yu F, Fu Y, Jiang C, Kong W
NPJ science of food 2023 Jul 17;7(1):36
NPJ science of food 2023 Jul 17;7(1):36
Maternal TDP-43 interacts with RNA Pol II and regulates zygotic genome activation.
Nie X, Xu Q, Xu C, Chen F, Wang Q, Qin D, Wang R, Gao Z, Lu X, Yang X, Wu Y, Gu C, Xie W, Li L
Nature communications 2023 Jul 17;14(1):4275
Nature communications 2023 Jul 17;14(1):4275
SNRPD1 inhibition suppresses the proliferation of hepatocellular carcinoma and promotes autophagy through the PI3K/AKT/mTOR/4EBP1 pathway.
Wang H, Chen M, Yang C, Hu H, Jiang Y, Yang F, Lv L
Archives of biochemistry and biophysics 2023 Jul 15;743:109661
Archives of biochemistry and biophysics 2023 Jul 15;743:109661
NAT10-mediated AXL mRNA N4-acetylcytidine modification promotes pancreatic carcinoma progression.
Zong G, Wang X, Guo X, Zhao Q, Wang C, Shen S, Xiao W, Yang Q, Jiang W, Shen J, Wan R
Experimental cell research 2023 Jul 15;428(2):113620
Experimental cell research 2023 Jul 15;428(2):113620
Schisandrin C enhances cGAS-STING pathway activation and inhibits HBV replication.
Zhao J, Xu G, Hou X, Mu W, Yang H, Shi W, Wen J, Liu T, Wu Z, Bai J, Zhang P, Wang Z, Xiao X, Zou W, Bai Z, Zhan X
Journal of ethnopharmacology 2023 Jul 15;311:116427
Journal of ethnopharmacology 2023 Jul 15;311:116427
A herbal product inhibits carbon tetrachloride-induced liver fibrosis by suppressing the epidermal growth factor receptor signaling pathway.
Qi J, Ping D, Sun X, Huang K, Peng Y, Liu C
Journal of ethnopharmacology 2023 Jul 15;311:116419
Journal of ethnopharmacology 2023 Jul 15;311:116419
MiR-29c-5p regulates the function of buffalo granulosa cells to induce follicular atresia by targeting INHBA.
Cheng J, Wei Y, Zhao Z, Xing Q, Gao Z, Cheng J, Yu C, Pan Y, Yang Y, Shi D, Deng Y
Theriogenology 2023 Jul 15;205:50-62
Theriogenology 2023 Jul 15;205:50-62
The ototoxic drug cisplatin localises to stress granules altering their dynamics and composition.
Martin JL, Terry SJ, Gale JE, Dawson SJ
Journal of cell science 2023 Jul 15;136(14)
Journal of cell science 2023 Jul 15;136(14)
Overexpression of POLA2 in hepatocellular carcinoma is involved in immune infiltration and predicts a poor prognosis.
Liu L, Wang Q, Wu L, Zhang L, Huang Y, Yang H, Guo L, Fang Z, Wang X
Cancer cell international 2023 Jul 14;23(1):138
Cancer cell international 2023 Jul 14;23(1):138
Reduced Vrk2 expression is associated with higher risk of depression in humans and mediates depressive-like behaviors in mice.
Yin MY, Guo L, Zhao LJ, Zhang C, Liu WP, Zhang CY, Huo JH, Wang L, Li SW, Zheng CB, Xiao X, Li M, Wang C, Chang H
BMC medicine 2023 Jul 14;21(1):256
BMC medicine 2023 Jul 14;21(1):256
Identification of a psychiatric risk gene NISCH at 3p21.1 GWAS locus mediating dendritic spine morphogenesis and cognitive function.
Yang ZH, Cai X, Ding ZL, Li W, Zhang CY, Huo JH, Zhang Y, Wang L, Zhang LM, Li SW, Li M, Zhang C, Chang H, Xiao X
BMC medicine 2023 Jul 13;21(1):254
BMC medicine 2023 Jul 13;21(1):254
CDC20 Is Regulated by the Histone Methyltransferase, KMT5A, in Castration-Resistant Prostate Cancer.
Alebady ZAH, Azizyan M, Nakjang S, Lishman-Walker E, Al-Kharaif D, Walker S, Choo HX, Garnham R, Scott E, Johnson KL, Robson CN, Coffey K
Cancers 2023 Jul 13;15(14)
Cancers 2023 Jul 13;15(14)
Exploring Cancer Dependency Map genes and immune subtypes in colon cancer, in which TIGD1 contributes to colon cancer progression.
Zhang G, Feng Z, Zeng Q, Huang P
Aging 2023 Jul 13;15(13):6400-6428
Aging 2023 Jul 13;15(13):6400-6428
Cytochrome c lysine acetylation regulates cellular respiration and cell death in ischemic skeletal muscle.
Morse PT, Pérez-Mejías G, Wan J, Turner AA, Márquez I, Kalpage HA, Vaishnav A, Zurek MP, Huettemann PP, Kim K, Arroum T, De la Rosa MA, Chowdhury DD, Lee I, Brunzelle JS, Sanderson TH, Malek MH, Meierhofer D, Edwards BFP, Díaz-Moreno I, Hüttemann M
Nature communications 2023 Jul 13;14(1):4166
Nature communications 2023 Jul 13;14(1):4166
N-carbamoyl aspartate reduced body weight by stimulating the thermogenesis of iBAT.
Wang Z, Zhang Y, Zhou T, Wu X
Biochemical and biophysical research communications 2023 Jul 12;665:152-158
Biochemical and biophysical research communications 2023 Jul 12;665:152-158
Lipopolysaccharide-induced sepsis impairs M2R-GIRK signaling in the mouse sinoatrial node.
Shrestha N, Zorn-Pauly K, Mesirca P, Koyani CN, Wölkart G, Di Biase V, Torre E, Lang P, Gorischek A, Schreibmayer W, Arnold R, Maechler H, Mayer B, von Lewinski D, Torrente AG, Mangoni ME, Pelzmann B, Scheruebel S
Proceedings of the National Academy of Sciences of the United States of America 2023 Jul 11;120(28):e2210152120
Proceedings of the National Academy of Sciences of the United States of America 2023 Jul 11;120(28):e2210152120
A coordinated multiorgan metabolic response contributes to human mitochondrial myopathy.
Southwell N, Primiano G, Nadkarni V, Attarwala N, Beattie E, Miller D, Alam S, Liparulo I, Shurubor YI, Valentino ML, Carelli V, Servidei S, Gross SS, Manfredi G, Chen Q, D'Aurelio M
EMBO molecular medicine 2023 Jul 10;15(7):e16951
EMBO molecular medicine 2023 Jul 10;15(7):e16951
Regulation of Sertoli cell function by planar cell polarity (PCP) protein Fjx1.
Bu T, Li X, Wang L, Wu X, Gao S, Yun D, Li L, Sun F, Cheng CY
Molecular and cellular endocrinology 2023 Jul 1;571:111936
Molecular and cellular endocrinology 2023 Jul 1;571:111936
Gut microbiota contribute to Methamphetamine-induced cardiotoxicity in mouse model.
Liu Y, Chen LJ, Li XW, Yang JZ, Liu JL, Zhang KK, Li JH, Wang Q, Xu JT, Zhi X
Chemico-biological interactions 2023 Jul 1;379:110512
Chemico-biological interactions 2023 Jul 1;379:110512
A multiparametric fluorescent visualization approach for detecting drug resistance in living cancer cells.
Zhou Z, Wang Y, Shao Z, Zhang G, Jiang H, Tang Y, Huang Z, Zhu Y, Li J
Talanta 2023 Jul 1;259:124564
Talanta 2023 Jul 1;259:124564
Lysine crotonylation of SERCA2a correlates to cardiac dysfunction and arrhythmia in Sirt1 cardiac-specific knockout mice.
Chen HX, Wang XC, Hou HT, Wang J, Yang Q, Chen YL, Chen HZ, He GW
International journal of biological macromolecules 2023 Jul 1;242(Pt 4):125151
International journal of biological macromolecules 2023 Jul 1;242(Pt 4):125151
Aligned lovastatin-loaded electrospun nanofibers regulate collagen organization and reduce scar formation.
Chen Z, Xiao L, Hu C, Shen Z, Zhou E, Zhang S, Wang Y
Acta biomaterialia 2023 Jul 1;164:240-252
Acta biomaterialia 2023 Jul 1;164:240-252
Hydrogen sulfide alleviates heart failure with preserved ejection fraction in mice by targeting mitochondrial abnormalities via PGC-1α.
Huang S, Chen X, Pan J, Zhang H, Ke J, Gao L, Yu Chang AC, Zhang J, Zhang H
Nitric oxide : biology and chemistry 2023 Jul 1;136-137:12-23
Nitric oxide : biology and chemistry 2023 Jul 1;136-137:12-23
DNA virus oncoprotein HPV18 E7 selectively antagonizes cGAS-STING-triggered innate immune activation.
Lou M, Huang D, Zhou Z, Shi X, Wu M, Rui Y, Su J, Zheng W, Yu XF
Journal of medical virology 2023 Jan;95(1):e28310
Journal of medical virology 2023 Jan;95(1):e28310
Hydrogen sulfide inhibits human T-cell leukemia virus type-1 (HTLV-1) protein expression via regulation of ATG4B.
Liu H, Sun J, Cheng X, Duan L, Guo S, Zhang Z, Wan J, Wang C, Zhi X, Yuan L, Wang H
Journal of medical virology 2023 Jan;95(1):e28176
Journal of medical virology 2023 Jan;95(1):e28176
SARS-CoV-2 ORF3a inhibits cGAS-STING-mediated autophagy flux and antiviral function.
Su J, Shen S, Hu Y, Chen S, Cheng L, Cai Y, Wei W, Wang Y, Rui Y, Yu XF
Journal of medical virology 2023 Jan;95(1):e28175
Journal of medical virology 2023 Jan;95(1):e28175
GSK3326595 is a promising drug to prevent SARS-CoV-2 Omicron and other variants infection by inhibiting ACE2-R671 di-methylation.
Li Z, Yong H, Wang W, Gao Y, Wang P, Chen X, Lu J, Zheng J, Bai J
Journal of medical virology 2023 Jan;95(1):e28158
Journal of medical virology 2023 Jan;95(1):e28158
Immune checkpoint PTPN2 predicts prognosis and immunotherapy response in human cancers.
Tang X, Sui X, Liu Y
Heliyon 2023 Jan;9(1):e12873
Heliyon 2023 Jan;9(1):e12873
Loss of Pten in Renal Tubular Cells Leads to Water Retention by Upregulating AQP2.
Sun Z, Shao X, Wu H, Zhao Y, Cao Y, Li D, Sun Y, Wang Q
Kidney diseases (Basel, Switzerland) 2023 Jan;9(1):58-71
Kidney diseases (Basel, Switzerland) 2023 Jan;9(1):58-71
Immunological profiles of human oligodendrogliomas define two distinct molecular subtypes.
Wu F, Yin YY, Fan WH, Zhai Y, Yu MC, Wang D, Pan CQ, Zhao Z, Li GZ, Zhang W
EBioMedicine 2023 Jan;87:104410
EBioMedicine 2023 Jan;87:104410
SIRT2 promotes cell proliferation and migration through mediating ERK1/2 activation and lactosylceramide accumulation in prostate cancer.
Lin R, Yang Y, Wu E, Zhou M, Wang S, Zhang Q
The Prostate 2023 Jan;83(1):71-81
The Prostate 2023 Jan;83(1):71-81
Overexpressed Cyclin D1 and CDK4 proteins are responsible for the resistance to CDK4/6 inhibitor in breast cancer that can be reversed by PI3K/mTOR inhibitors.
Cai Z, Wang J, Li Y, Shi Q, Jin L, Li S, Zhu M, Wang Q, Wong LL, Yang W, Lai H, Gong C, Yao Y, Liu Y, Zhang J, Yao H, Liu Q
Science China. Life sciences 2023 Jan;66(1):94-109
Science China. Life sciences 2023 Jan;66(1):94-109
SATB1/SLC7A11/HO-1 Axis Ameliorates Ferroptosis in Neuron Cells After Ischemic Stroke by Danhong Injection.
Zhan S, Liang J, Lin H, Cai J, Yang X, Wu H, Wei J, Wang S, Xian M
Molecular neurobiology 2023 Jan;60(1):413-427
Molecular neurobiology 2023 Jan;60(1):413-427
MicroRNA profiling reveals the role of miR-133b-3p in promoting apoptosis and inhibiting cell proliferation and testosterone synthesis in mouse TM3 cells.
Pan C, Fei Q, Jin J, Zheng J, Wu D, Li H, Huang X, Kong X
In vitro cellular & developmental biology. Animal 2023 Jan;59(1):63-75
In vitro cellular & developmental biology. Animal 2023 Jan;59(1):63-75
Actin related protein 2/3 complex subunit 1 up-regulation in the hypothalamus prevents high-fat diet induced obesity.
Ni W, Zhang J, Wang B, Liang F, Bao L, Li P, Fang Y
The European journal of neuroscience 2023 Jan;57(1):64-77
The European journal of neuroscience 2023 Jan;57(1):64-77
Site-specific ubiquitination of VDAC1 restricts its oligomerization and mitochondrial DNA release in liver fibrosis.
Wu NN, Wang L, Wang L, Xu X, Lopaschuk GD, Zhang Y, Ren J
Experimental & molecular medicine 2023 Jan;55(1):269-280
Experimental & molecular medicine 2023 Jan;55(1):269-280
The Correlation between Increased Expressions of NLRP3 Inflammasome Components in Peripheral Blood Mono-Nuclear Cells and Plaque Vulnerability in Human Carotid Atherosclerosis.
Xie W, Shi X, Lee H, Wang L, Niu N, Qu P
Iranian journal of public health 2023 Jan;52(1):147-158
Iranian journal of public health 2023 Jan;52(1):147-158
Ginsenoside Rg3 liposomes regulate tumor microenvironment for the treatment of triple negative breast cancer.
Miao L, Ma H, Dong T, Zhao C, Gao T, Wu T, Xu H, Zhang J
Drug development and industrial pharmacy 2023 Jan;49(1):139-148
Drug development and industrial pharmacy 2023 Jan;49(1):139-148
Prefoldin 6 promotes glioma progression via the AKT signalling pathway.
Jiang L, Liu J
Cell biology international 2023 Jan;47(1):52-62
Cell biology international 2023 Jan;47(1):52-62
SPARC expression in tumor microenvironment induces partial epithelial-to-mesenchymal transition of esophageal adenocarcinoma cells via cooperating with TGF-β signaling.
Ma W, Yan Y, Bai S, Zhou Y, Wang X, Feng Z, Li G, Zhou S, Zhang J, Ren J
Cell biology international 2023 Jan;47(1):250-259
Cell biology international 2023 Jan;47(1):250-259
Imbalance in ALR ubiquitination accelerates the progression of nonalcoholic steatohepatitis to hepatocellular carcinoma.
Zheng M, Ai Z, Guo Y, Chen Y, Xie P, An W
Oncogene 2023 Jan;42(4):308-321
Oncogene 2023 Jan;42(4):308-321
Long non-coding RNA HOXC-AS1 exerts its oncogenic effects in esophageal squamous cell carcinoma by interaction with IGF2BP2 to stabilize SIRT1 expression.
Yang Z, Wan J, Ma L, Li Z, Yang R, Yang H, Li J, Zhou F, Ming L
Journal of clinical laboratory analysis 2023 Jan;37(1):e24801
Journal of clinical laboratory analysis 2023 Jan;37(1):e24801
Resveratrol reverses TGF-β1-mediated invasion and metastasis of breast cancer cells via the SIRT3/AMPK/autophagy signal axis.
Wang J, Huang P, Pan X, Xia C, Zhang H, Zhao H, Yuan Z, Liu J, Meng C, Liu F
Phytotherapy research : PTR 2023 Jan;37(1):211-230
Phytotherapy research : PTR 2023 Jan;37(1):211-230
M1/M2 re-polarization of kaempferol biomimetic NPs in anti-inflammatory therapy of atherosclerosis.
Zhao J, Ling L, Zhu W, Ying T, Yu T, Sun M, Zhu X, Du Y, Zhang L
Journal of controlled release : official journal of the Controlled Release Society 2023 Jan;353:1068-1083
Journal of controlled release : official journal of the Controlled Release Society 2023 Jan;353:1068-1083
Attenuation of Piwil2 induced by hypoxic postconditioning prevents cerebral ischemic injury by inhibiting CREB2 promoter methylation.
Zhan L, Chen M, Pang T, Li X, Long L, Liang D, Peng L, Sun W, Xu E
Brain pathology (Zurich, Switzerland) 2023 Jan;33(1):e13109
Brain pathology (Zurich, Switzerland) 2023 Jan;33(1):e13109
Lysine-40 succinylation of TAGLN2 induces glioma angiogenesis and tumor growth through regulating TMSB4X.
Zhang X, Han J, Fan D, Wang J, Lin X, Zhang H, Zhang C, Bai J, Huang H, Gu Y
Cancer gene therapy 2023 Jan;30(1):172-181
Cancer gene therapy 2023 Jan;30(1):172-181
Melatonin Increases Proliferation and Decreases Apoptosis of GC-1 spg Cells by Upregulating the Expression of circTec.
Xu C, Yang H, Li C, Wu Z, Ma Y
Reproductive sciences (Thousand Oaks, Calif.) 2023 Jan;30(1):135-144
Reproductive sciences (Thousand Oaks, Calif.) 2023 Jan;30(1):135-144
Ginsenoside Rg1 promotes astrocyte-to-neuron transdifferentiation in rat and its possible mechanism.
Shen K, Wu D, Sun B, Zhu Y, Wang H, Zou W, Ma Y, Lu Z
CNS neuroscience & therapeutics 2023 Jan;29(1):256-269
CNS neuroscience & therapeutics 2023 Jan;29(1):256-269
Depletion of SASH1, an astrocyte differentiation-related gene, contributes to functional recovery in spinal cord injury.
Liu S, Lin G, Yang Q, Wang P, Ma C, Qian X, He X, Dong Z, Liu Y, Liu M, Wu R, Yang L
CNS neuroscience & therapeutics 2023 Jan;29(1):228-238
CNS neuroscience & therapeutics 2023 Jan;29(1):228-238
miR-27a-3p targets NR5A2 to regulate CYP19A1 expression and 17-β estradiol synthesis in ovine granulosa cells.
Gui H, Li F, Chen C, Zhu Q, Zhang C, Zhang J, Meng C, Qian Y, Cao S, Li Y
Animal reproduction science 2023 Jan;248:107160
Animal reproduction science 2023 Jan;248:107160
iPSC-based model of Vogt-Koyanagi-Harada disease for phenotype recapitulation and drug screening.
Li W, Tan J, He S, Yue Y, Liu H, Li R, Wang X, Wang G, Fan W, Zhao C, Zhou Q, Yang P, Hou S
Clinical immunology (Orlando, Fla.) 2023 Jan;246:109205
Clinical immunology (Orlando, Fla.) 2023 Jan;246:109205
AP2S1 regulates APP degradation through late endosome-lysosome fusion in cells and APP/PS1 mice.
Wen QX, Luo B, Xie XY, Zhou GF, Chen J, Song L, Liu Y, Xie SQ, Chen L, Li KY, Xiang XJ, Chen GJ
Traffic (Copenhagen, Denmark) 2023 Jan;24(1):20-33
Traffic (Copenhagen, Denmark) 2023 Jan;24(1):20-33
CCNE1 is a potential target of Metformin for tumor suppression of ovarian high-grade serous carcinoma.
Mei J, Tian H, Huang HS, Wu N, Liou YL, Chu TY, Wang J, Zhang W
Cell cycle (Georgetown, Tex.) 2023 Jan;22(1):85-99
Cell cycle (Georgetown, Tex.) 2023 Jan;22(1):85-99
A novel 3-phenylglutaric acid derivative (84-B10) alleviates cisplatin-induced acute kidney injury by inhibiting mitochondrial oxidative stress-mediated ferroptosis.
Fan J, Xu X, Li Y, Zhang L, Miao M, Niu Y, Zhang Y, Zhang A, Jia Z, Wu M
Free radical biology & medicine 2023 Jan;194:84-98
Free radical biology & medicine 2023 Jan;194:84-98
Targeting RNA G-quadruplex with repurposed drugs blocks SARS-CoV-2 entry.
Tong Q, Liu G, Sang X, Zhu X, Fu X, Dou C, Jian Y, Zhang J, Zou S, Zhang G, Du X, Liu D, Qi S, Cheng W, Tian Y, Fu X
PLoS pathogens 2023 Jan;19(1):e1011131
PLoS pathogens 2023 Jan;19(1):e1011131
Palmitic acid induces nDNA release to cytosol and promotes microglial M1 polarization via cGAS-STING signaling pathway.
Deng Y, Yi X, Gong Y, Zhou L, Xie D, Wang J, Liu Z, Zhang Y, Wu W
Biochimica et biophysica acta. Molecular cell research 2023 Jan;1870(1):119385
Biochimica et biophysica acta. Molecular cell research 2023 Jan;1870(1):119385
RNA-binding motif 4 promotes angiogenesis in HCC by selectively activating VEGF-A expression.
Han H, Lin T, Wang Z, Song J, Fang Z, Zhang J, You X, Du Y, Ye J, Zhou G
Pharmacological research 2023 Jan;187:106593
Pharmacological research 2023 Jan;187:106593
Icariin ameliorates memory deficits through regulating brain insulin signaling and glucose transporters in 3×Tg-AD mice.
Yan F, Liu J, Chen MX, Zhang Y, Wei SJ, Jin H, Nie J, Fu XL, Shi JS, Zhou SY, Jin F
Neural regeneration research 2023 Jan;18(1):183-188
Neural regeneration research 2023 Jan;18(1):183-188
Reactive oxygen species-induced long intergenic noncoding RNA p21 accelerates abdominal aortic aneurysm formation by promoting secretary smooth muscle cell phenotypes.
Wang S, Wang J, Cai D, Li X, Zhong L, He X, Lin Z, Lai Y, Zheng H, Zhou Y, Xiao Z, Liao W, Liao Y, Xiu J, Bin J
Journal of molecular and cellular cardiology 2023 Jan;174:63-76
Journal of molecular and cellular cardiology 2023 Jan;174:63-76
Exposure to dithiocarbamate fungicide maneb in vitro and in vivo: Neuronal apoptosis and underlying mechanisms.
Liu C, Liu Z, Fang Y, Liao Z, Zhang Z, Yuan X, Yu T, Yang Y, Xiong M, Zhang X, Zhang G, Meng L, Zhang Z
Environment international 2023 Jan;171:107696
Environment international 2023 Jan;171:107696
Inhibition of interaction between ROCK1 and Rubicon restores autophagy in endothelial cells and attenuates brain injury after prolonged ischemia.
Lin Y, Zhan Z, Hu M, Li H, Zhang B, Wu R, Tan S, Shan Y, Lu Z, Qin B
Journal of neurochemistry 2023 Jan;164(2):172-192
Journal of neurochemistry 2023 Jan;164(2):172-192
CircSETD3 mediates acquired resistance to gefitinib in non-small lung cancer cells by FXR1/ECT2 pathway.
Wen C, Li Y, Huang Y, Wang N, He S, Bao M, Zhou H, Wu L
The international journal of biochemistry & cell biology 2023 Jan;154:106344
The international journal of biochemistry & cell biology 2023 Jan;154:106344
Characterization of DJ-1, PTEN, and p-Akt as Prognostic Biomarkers in the Progression of Oral Squamous Cell Carcinoma.
Kerdjoudj M, De La Torre RA, Arnouk H
Cureus 2023 Jan;15(1):e34436
Cureus 2023 Jan;15(1):e34436
A hnRNPA2B1 agonist effectively inhibits HBV and SARS-CoV-2 omicron in vivo.
Zuo D, Chen Y, Cai JP, Yuan HY, Wu JQ, Yin Y, Xie JW, Lin JM, Luo J, Feng Y, Ge LJ, Zhou J, Quinn RJ, Zhao SJ, Tong X, Jin DY, Yuan S, Dai SX, Xu M
Protein & cell 2023 Jan;14(1):37-50
Protein & cell 2023 Jan;14(1):37-50
Effects of leptin treatment immediately after neonatal seizures on serum clusterin and VEGF levels and brain oxidative stress-related proteins and neurobehavioral phenotypes.
Li Y, Jin M, Yin X, Zhou B, Ni H
Epilepsy & behavior : E&B 2023 Jan;138:109016
Epilepsy & behavior : E&B 2023 Jan;138:109016
CgTNF-2 promotes the proliferation of haemocytes by regulating the expressions of CgRunx and cell cycle related genes in the Pacific oyster Crassostrea gigas.
Wu W, Sun J, Dong M, Yang Q, Yang W, Zhang T, Wang L, Song L
Fish & shellfish immunology 2023 Jan;132:108478
Fish & shellfish immunology 2023 Jan;132:108478
Dihydrotanshinone I preconditions myocardium against ischemic injury via PKM2 glutathionylation sensitive to ROS.
Wu X, Liu L, Zheng Q, Ye H, Yang H, Hao H, Li P
Acta pharmaceutica Sinica. B 2023 Jan;13(1):113-127
Acta pharmaceutica Sinica. B 2023 Jan;13(1):113-127
Capecitabine induces hand-foot syndrome through elevated thymidine phosphorylase-mediated locoregional toxicity and GSDME-driven pyroptosis that can be relieved by tipiracil.
Yang B, Xie X, Lv D, Hu J, Chen Y, Wu Z, Luo S, Zhang S
British journal of cancer 2023 Jan;128(2):219-231
British journal of cancer 2023 Jan;128(2):219-231
An In Vitro Engineered Osteochondral Model as Tool to Study Osteoarthritis Environment.
Scalzone A, Cerqueni G, Wang XN, Ferreira-Duarte A, Dalgarno K, Mattioli-Belmonte M, Gentile P
Advanced healthcare materials 2023 Jan;12(2):e2202030
Advanced healthcare materials 2023 Jan;12(2):e2202030
EphrinA3 is a key regulator of malignant behaviors and a potential prognostic factor in lung adenocarcinoma.
Yiminniyaze R, Zhang X, Zhu N, Wang J, Li C, Wumaier G, Zhou D, Li J, Xia J, Zhang Y, Dong L, Zhang Y, Li S
Cancer medicine 2023 Jan;12(2):1630-1642
Cancer medicine 2023 Jan;12(2):1630-1642
Neurogranin as an important regulator in swimming training to improve the spatial memory dysfunction of mice with chronic cerebral hypoperfusion.
Lin H, Zhang J, Dai Y, Liu H, He X, Chen L, Tao J, Li C, Liu W
Journal of sport and health science 2023 Jan;12(1):116-129
Journal of sport and health science 2023 Jan;12(1):116-129
Treponema pallidum lipoprotein Tp0768 promotes the migration and adhesion of THP-1 cells to vascular endothelial cells through stress of the endoplasmic reticulum and the NF-κB/HIF-1α pathway.
Zhou X, Tang Y, Cao T, Ning L, Li Y, Xie X, Hu Y, He B, Peng B, Liu S
Molecular microbiology 2023 Jan;119(1):86-100
Molecular microbiology 2023 Jan;119(1):86-100
Molecular hydrogen attenuates sepsis-induced cognitive dysfunction through regulation of tau phosphorylation.
Qi B, Song Y, Chen C, Zhao L, Ma W, Meng S, Zhuang X, Lin H, Liang J, Cui Y, Xie K
International immunopharmacology 2023 Jan;114:109603
International immunopharmacology 2023 Jan;114:109603
Protective effects of leonurine hydrochloride on pyroptosis in premature ovarian insufficiency via regulating NLRP3/GSDMD pathway.
Chi YN, Hai DM, Ma L, Cui YH, Hu HT, Liu N, Juan-Du, Lan XB, Yu JQ, Yang JM
International immunopharmacology 2023 Jan;114:109520
International immunopharmacology 2023 Jan;114:109520
Copper transporter gene ATP7A: A predictive biomarker for immunotherapy and targeted therapy in hepatocellular carcinoma.
Shao K, Shen H, Chen X, Shao Z, Liu Y, Wang Y, Chen H, Wu X
International immunopharmacology 2023 Jan;114:109518
International immunopharmacology 2023 Jan;114:109518
The effects of taraxasterol on liver fibrosis revealed by RNA sequencing.
He H, Xu B, Ge P, Gao Y, Wei M, Li T, Zhang R, Li B, Cao H, Zhang K
International immunopharmacology 2023 Jan;114:109481
International immunopharmacology 2023 Jan;114:109481
Treatment with butyrate alleviates dextran sulfate sodium and Clostridium difficile-induced colitis by preventing activity of Th17 cells via regulation of SIRT1/mTOR in mice.
Wang S, Deng W, Li F, Xiang L, Lv P, Chen Y
The Journal of nutritional biochemistry 2023 Jan;111:109155
The Journal of nutritional biochemistry 2023 Jan;111:109155
M13, an anthraquinone compound isolated from Morinda officinalis promotes the osteogenic differentiation of MSCs by targeting Wnt/β-catenin signaling.
Li C, Tian L, Wang Y, Luo H, Zeng J, Su P, Chen S, Liao Z, Guo W, He X, Chen S, Xu C
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Jan;108:154542
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Jan;108:154542
The mechanisms of Qizhu Tangshen formula in the treatment of diabetic kidney disease: Network pharmacology, machine learning, molecular docking and experimental assessment.
Peng J, Yang K, Tian H, Lin Y, Hou M, Gao Y, Zhou X, Gao Z, Ren J
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Jan;108:154525
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Jan;108:154525
Glycocholic acid aggravates liver fibrosis by promoting the up-regulation of connective tissue growth factor in hepatocytes.
Yuan Z, Wang J, Zhang H, Chai Y, Xu Y, Miao Y, Yuan Z, Zhang L, Jiang Z, Yu Q
Cellular signalling 2023 Jan;101:110508
Cellular signalling 2023 Jan;101:110508
Desulfovibrio desulfuricans aggravates atherosclerosis by enhancing intestinal permeability and endothelial TLR4/NF-κB pathway in Apoe (-/-) mice.
Zhang K, Qin X, Qiu J, Sun T, Qu K, Din AU, Yan W, Li T, Chen Y, Gu W, Rao X, Wang G
Genes & diseases 2023 Jan;10(1):239-253
Genes & diseases 2023 Jan;10(1):239-253
Heparanase Contributes to Psoriatic Lesions Through Crosstalk with IL-17 Pathway.
Zhu C, Ren Y, Yao H, Feng B, Liu L, Zheng M
Indian journal of dermatology 2023 Jan-Feb;68(1):59-66
Indian journal of dermatology 2023 Jan-Feb;68(1):59-66
Systemic Administration of Lipopolysaccharide from Porphyromonas gingivalis Decreases Neprilysin Expression in the Mouse Hippocampus.
Morikawa T, Uehara O, Paudel D, Yoshida K, Harada F, Hiraki D, Sato J, Matsuoka H, Kuramitsu Y, Michikawa M, Abiko Y
In vivo (Athens, Greece) 2023 Jan-Feb;37(1):163-172
In vivo (Athens, Greece) 2023 Jan-Feb;37(1):163-172
Exosomes From Adipose-Derived Stem Cells Suppress the Progression of Chronic Endometritis.
Wang B, Li L, Yu R
Cell transplantation 2023 Jan-Dec;32:9636897231173736
Cell transplantation 2023 Jan-Dec;32:9636897231173736
Babao Dan Alleviates Cancer Cachexia in Mice Via Inhibiting IL-6/STAT3 Signaling Pathway.
Qiu Z, Wo D, Zhong X, Chen J, Ma E, He J, Peng J, Zhu W, Ren DN
Integrative cancer therapies 2023 Jan-Dec;22:15347354231168369
Integrative cancer therapies 2023 Jan-Dec;22:15347354231168369
Predictive Models for Colon Adenocarcinoma Diagnosis, Prognosis, and Immune Microenvironment Based on 2 Hypoxia-Related Genes: KDM3A and ENO3.
Kong C, Zheng L, Fang S, Chen M, Lin G, Qiu R, Zhao Z, Chen W, Song J, Yang Y, Ji J
Technology in cancer research & treatment 2023 Jan-Dec;22:15330338231195494
Technology in cancer research & treatment 2023 Jan-Dec;22:15330338231195494
TRIM11 Posttranscriptionally Modulated by miR-5193 Facilitates Tumor Growth and Metastasis of Prostate Cancer.
Pan Y, Yu H, Lu F
Technology in cancer research & treatment 2023 Jan-Dec;22:15330338231178639
Technology in cancer research & treatment 2023 Jan-Dec;22:15330338231178639
MicroRNA-1205 Suppresses Hepatocellular Carcinoma Cell Proliferation via a CSNK2B/CDK4 Axis.
Li X, Xie S, Xia Q, Yan J, Chen S, Shen J
Technology in cancer research & treatment 2023 Jan-Dec;22:15330338221150544
Technology in cancer research & treatment 2023 Jan-Dec;22:15330338221150544
Exosomal-miR-129-2-3p derived from Fusobacterium nucleatum-infected intestinal epithelial cells promotes experimental colitis through regulating TIMELESS-mediated cellular senescence pathway.
Wei S, Wu X, Chen M, Xiang Z, Li X, Zhang J, Dong W
Gut microbes 2023 Jan-Dec;15(1):2240035
Gut microbes 2023 Jan-Dec;15(1):2240035
Therapeutic potential of Clostridium butyricum anticancer effects in colorectal cancer.
Xu H, Luo H, Zhang J, Li K, Lee MH
Gut microbes 2023 Jan-Dec;15(1):2186114
Gut microbes 2023 Jan-Dec;15(1):2186114
Calcium Phosphate Bone Cements Incorporated with Black Phosphorus Nanosheets Enhanced Osteogenesis.
Ma S, Wei Y, Sun R, Xu H, Liu X, Wang Y, Liang Z, Hu Y, Lian X, Ma X, Huang D
ACS biomaterials science & engineering 2023 Jan 9;9(1):292-302
ACS biomaterials science & engineering 2023 Jan 9;9(1):292-302
iTRAQ-based Proteomic Analysis Unveils ACSL4 as a Novel Potential Regulator of Human Endometrial Receptivity.
Hu S, Sun Z, Li B, Zhao H, Wang Y, Yao G, Li X, Bian X, Li TC, Vankelecom H, Sun Y
Endocrinology 2023 Jan 9;164(3)
Endocrinology 2023 Jan 9;164(3)
The CDK inhibitor AT7519 inhibits human glioblastoma cell growth by inducing apoptosis, pyroptosis and cell cycle arrest.
Zhao W, Zhang L, Zhang Y, Jiang Z, Lu H, Xie Y, Han W, Zhao W, He J, Shi Z, Yang H, Chen J, Chen S, Li Z, Mao J, Zhou L, Gao X, Li W, Tan G, Zhang B, Wang Z
Cell death & disease 2023 Jan 9;14(1):11
Cell death & disease 2023 Jan 9;14(1):11
TEAD4 is a master regulator of high-risk nasopharyngeal carcinoma.
Wang YQ, Wu DH, Wei D, Shen JY, Huang ZW, Liang XY, Cho WCS, Ma J, Lv J, Chen YP
Science advances 2023 Jan 6;9(1):eadd0960
Science advances 2023 Jan 6;9(1):eadd0960
Downregulation of CEMIP enhances radiosensitivity by promoting DNA damage and apoptosis in colorectal cancer.
Weng J, Zhang Y, Liang W, Xie Y, Wang K, Xu Q, Ding Y, Li Y
Medical oncology (Northwood, London, England) 2023 Jan 6;40(2):73
Medical oncology (Northwood, London, England) 2023 Jan 6;40(2):73
Mitofusin 2 mutation drives cell proliferation in Charcot-Marie-Tooth 2A fibroblasts.
Zanfardino P, Longo G, Amati A, Morani F, Picardi E, Girolamo F, Pafundi M, Cox SN, Manzari C, Tullo A, Doccini S, Santorelli FM, Petruzzella V
Human molecular genetics 2023 Jan 6;32(2):333-350
Human molecular genetics 2023 Jan 6;32(2):333-350
Cadmium Activates EGFR/STAT5 Signaling to Overcome Calcium Chelation and Promote Epithelial to Mesenchymal Transition.
Stavrou A, Ortiz A, Costa M
Biomolecules 2023 Jan 6;13(1)
Biomolecules 2023 Jan 6;13(1)
ALKBH5 prevents hepatocellular carcinoma progression by post-transcriptional inhibition of PAQR4 in an m6A dependent manner.
Wang W, Huang Q, Liao Z, Zhang H, Liu Y, Liu F, Chen X, Zhang B, Chen Y, Zhu P
Experimental hematology & oncology 2023 Jan 6;12(1):1
Experimental hematology & oncology 2023 Jan 6;12(1):1
Baicalin prevents fibrosis of human trabecular meshwork cells via inhibiting the MyD88/NF-κB pathway.
Li L, Liu Q, Shi L, Zhou X, Wu W, Wang X, Wang L, Wu Z
European journal of pharmacology 2023 Jan 5;938:175425
European journal of pharmacology 2023 Jan 5;938:175425
An enhancer-based gene-therapy strategy for spatiotemporal control of cargoes during tissue repair.
Yan R, Cigliola V, Oonk KA, Petrover Z, DeLuca S, Wolfson DW, Vekstein A, Mendiola MA, Devlin G, Bishawi M, Gemberling MP, Sinha T, Sargent MA, York AJ, Shakked A, DeBenedittis P, Wendell DC, Ou J, Kang J, Goldman JA, Baht GS, Karra R, Williams AR, Bowles DE, Asokan A, Tzahor E, Gersbach CA, Molkentin JD, Bursac N, Black BL, Poss KD
Cell stem cell 2023 Jan 5;30(1):96-111.e6
Cell stem cell 2023 Jan 5;30(1):96-111.e6
Decoding m(6)A RNA methylome identifies PRMT6-regulated lipid transport promoting AML stem cell maintenance.
Cheng Y, Gao Z, Zhang T, Wang Y, Xie X, Han G, Li Y, Yin R, Chen Y, Wang P, Hu J, Zhang T, Guo C, Chai J, Wang J, Cui M, Gao K, Liu W, Yao S, Lu P, Cao Z, Zheng Y, Chang J, Liu Z, Song Q, Li W, Zhou F, Zhang H
Cell stem cell 2023 Jan 5;30(1):69-85.e7
Cell stem cell 2023 Jan 5;30(1):69-85.e7
Fusobacterium nucleatum Extracellular Vesicles Promote Experimental Colitis by Modulating Autophagy via the miR-574-5p/CARD3 Axis.
Wei S, Zhang J, Wu X, Chen M, Huang H, Zeng S, Xiang Z, Li X, Dong W
Inflammatory bowel diseases 2023 Jan 5;29(1):9-26
Inflammatory bowel diseases 2023 Jan 5;29(1):9-26
A Mulberry Diels-Alder-Type Adduct, Kuwanon M, Triggers Apoptosis and Paraptosis of Lung Cancer Cells through Inducing Endoplasmic Reticulum Stress.
Ma M, Luan X, Zheng H, Wang X, Wang S, Shen T, Ren D
International journal of molecular sciences 2023 Jan 5;24(2)
International journal of molecular sciences 2023 Jan 5;24(2)
Decapping factor Dcp2 controls mRNA abundance and translation to adjust metabolism and filamentation to nutrient availability.
Vijjamarri AK, Niu X, Vandermeulen MD, Onu C, Zhang F, Qiu H, Gupta N, Gaikwad S, Greenberg ML, Cullen PJ, Lin Z, Hinnebusch AG
bioRxiv : the preprint server for biology 2023 Jan 5;
bioRxiv : the preprint server for biology 2023 Jan 5;
SIGIRR-caspase-8 signaling mediates endothelial apoptosis in Kawasaki disease.
Wen Z, Xia Y, Zhang Y, He Y, Niu C, Wu R, Zhang C, Jia C, Rong X, Chu M
Italian journal of pediatrics 2023 Jan 4;49(1):2
Italian journal of pediatrics 2023 Jan 4;49(1):2
A high-efficient and naked-eye visible CRISPR/Cas9 system in Arabidopsis.
Kong W, Wang M, Huang L, Wu F, Tao J, Mo B, Yu Y
Planta 2023 Jan 4;257(2):30
Planta 2023 Jan 4;257(2):30
The deubiquitinase OTUD1 noncanonically suppresses Akt activation through its N-terminal intrinsically disordered region.
Fan G, Wang F, Chen Y, Zheng Q, Xiong J, Lv Q, Wu K, Xiong J, Wei L, Li D, Zhang J, Zhang W, Li F
Cell reports 2023 Jan 31;42(1):111916
Cell reports 2023 Jan 31;42(1):111916
The Effect of the Histone Chaperones HSPA8 and DEK on Tumor Immunity in Hepatocellular Carcinoma.
Yang C, Shao Y, Wang X, Wang J, Wang P, Huang C, Wang W, Wang J
International journal of molecular sciences 2023 Jan 31;24(3)
International journal of molecular sciences 2023 Jan 31;24(3)
5'-tRF-GlyGCC promotes breast cancer metastasis by increasing fat mass and obesity-associated protein demethylase activity.
Chen F, Song C, Meng F, Zhu Y, Chen X, Fang X, Ma D, Wang Y, Zhang C
International journal of biological macromolecules 2023 Jan 31;226:397-409
International journal of biological macromolecules 2023 Jan 31;226:397-409
Effects of acupuncture on the miR-146a-mediated IRAK1/TRAF6/NF-κB signaling pathway in rats with sarcopenia induced by D-galactose.
Jin J, Yang Z, Liu H, Guo M, Chen B, Zhu H, Wang Y, Lin J, Wang S, Chen S
Annals of translational medicine 2023 Jan 31;11(2):47
Annals of translational medicine 2023 Jan 31;11(2):47
Hypermetabolism in mice carrying a near complete human chromosome 21.
Sarver DC, Xu C, Rodriguez S, Aja S, Jaffe AE, Gao FJ, Delannoy M, Periasamy M, Kazuki Y, Oshimura M, Reeves RH, Wong GW
bioRxiv : the preprint server for biology 2023 Jan 31;
bioRxiv : the preprint server for biology 2023 Jan 31;
AGEs induce endothelial cells senescence and endothelial barrier dysfunction via miR-1-3p/MLCK signaling pathways.
Cheng M, Yang Z, Qiao L, Yang Y, Deng Y, Zhang C, Mi T
Gene 2023 Jan 30;851:147030
Gene 2023 Jan 30;851:147030
Biejiajian pill inhibits progression of hepatocellular carcinoma by downregulating PDGFRβ signaling in cancer-associated fibroblasts.
Chen W, Yang X, Sun J, Chen Y, Zhao W, He C, An H, Pang J, Xu W, Wen B, Sun H, He S
Journal of ethnopharmacology 2023 Jan 30;301:115825
Journal of ethnopharmacology 2023 Jan 30;301:115825
Hordenine Activated Dermal Papilla Cells and Promoted Hair Regrowth by Activating Wnt Signaling Pathway.
Wang C, Zang K, Tang Z, Yang T, Ye X, Dang Y
Nutrients 2023 Jan 30;15(3)
Nutrients 2023 Jan 30;15(3)
Adipose-specific deletion of the cation channel TRPM7 inhibits TAK1 kinase-dependent inflammation and obesity in male mice.
Zhong W, Ma M, Xie J, Huang C, Li X, Gao M
Nature communications 2023 Jan 30;14(1):491
Nature communications 2023 Jan 30;14(1):491
LncRNA WDR11-AS1 Promotes Extracellular Matrix Synthesis in Osteoarthritis by Directly Interacting with RNA-Binding Protein PABPC1 to Stabilize SOX9 Expression.
Huang H, Yan J, Lan X, Guo Y, Sun M, Zhao Y, Zhang F, Sun J, Lu S
International journal of molecular sciences 2023 Jan 3;24(1)
International journal of molecular sciences 2023 Jan 3;24(1)
Perinatal Fat-Diets Increased Angiotensin II-Mediated Ca(2+) through PKC-L-Type Calcium Channel Axis in Resistance Arteries via Agtr1a-Prkcb Gene Methylation.
Zheng Q, He Y, Li L, Rui C, Li N, Zhang Y, Ye Y, Zhang Z, Yang X, Tang J, Xu Z
Nutrients 2023 Jan 3;15(1)
Nutrients 2023 Jan 3;15(1)
Ginsenoside Rb1 induces autophagic lipid degradation via miR-128 targeting TFEB.
Meng Z, Lu J, Ge G, Wang G, Zhang R, Li Y, Guan S, Lu J
Food & function 2023 Jan 3;14(1):240-249
Food & function 2023 Jan 3;14(1):240-249
MFG-E8 stabilized by deubiquitinase USP14 suppresses cigarette smoke-induced ferroptosis in bronchial epithelial cells.
Cui Y, Luo L, Zeng Z, Liu X, Li T, He X, Ma Y, Meng W, Zeng H, Long Y, Zong D, Chen Y
Cell death & disease 2023 Jan 3;14(1):2
Cell death & disease 2023 Jan 3;14(1):2
Antisense oligonucleotide therapy rescues disturbed brain rhythms and sleep in juvenile and adult mouse models of Angelman syndrome.
Lee D, Chen W, Kaku HN, Zhuo X, Chao ES, Soriano A, Kuncheria A, Flores S, Kim JH, Rivera A, Rigo F, Jafar-Nejad P, Beaudet AL, Caudill MS, Xue M
eLife 2023 Jan 3;12
eLife 2023 Jan 3;12
TMBIM4 Deficiency Facilitates NLRP3 Inflammasome Activation-Induced Pyroptosis of Trophoblasts: A Potential Pathogenesis of Preeclampsia.
Chen Y, Xiao L, Sun G, Li M, Yang H, Ming Z, Zhao K, Shang X, Zhang H, Liu C
Biology 2023 Jan 29;12(2)
Biology 2023 Jan 29;12(2)
Ciclopirox Inhibition of eIF5A Hypusination Attenuates Fibroblast Activation and Cardiac Fibrosis.
Subbaiah KCV, Wu J, Tang WHW, Yao P
Journal of cardiovascular development and disease 2023 Jan 29;10(2)
Journal of cardiovascular development and disease 2023 Jan 29;10(2)
Development of a Novel (18)F-Labeled Probe for PET Imaging of Estrogen Receptor β.
Zhou Y, Lei P, Han J, Wang Z, Ji A, Wu Y, Zheng L, Zhang X, Qu C, Min J, Zhu W, Xu Z, Liu X, Chen H, Cheng Z
Journal of medicinal chemistry 2023 Jan 26;66(2):1210-1220
Journal of medicinal chemistry 2023 Jan 26;66(2):1210-1220
TRIM21 attenuates renal carcinoma lipogenesis and malignancy by regulating SREBF1 protein stability.
Chen X, Yong H, Chen M, Deng C, Wang P, Chu S, Li M, Hou P, Zheng J, Li Z, Bai J
Journal of experimental & clinical cancer research : CR 2023 Jan 25;42(1):34
Journal of experimental & clinical cancer research : CR 2023 Jan 25;42(1):34
[WITHDRAWN] Hexokinase-1 mitochondrial dissociation and protein O-GlcNAcylation drive heart failure with preserved ejection fraction.
Tatekoshi Y, Shapiro JS, Liu M, Bianco GM, Tatekoshi A, De Jesus A, Koleini N, Wasserstrom JA, Dillmann WH, Weinberg SE, Ardehali H
Research square 2023 Jan 25;
Research square 2023 Jan 25;
SIRT2 inhibition protects against cardiac hypertrophy and heart failure.
Yang X, Chang HC, Tatekoshi Y, Balibegloo M, Wu R, Chen C, Sato T, Shapiro J, Ardehali H
bioRxiv : the preprint server for biology 2023 Jan 25;
bioRxiv : the preprint server for biology 2023 Jan 25;
LARP6 suppresses colorectal cancer progression through ZNF267/SGMS2-mediated imbalance of sphingomyelin synthesis.
Long X, Liu X, Deng T, Chen J, Lan J, Zhang S, Zhou M, Guo D, Zhou J
Journal of experimental & clinical cancer research : CR 2023 Jan 24;42(1):33
Journal of experimental & clinical cancer research : CR 2023 Jan 24;42(1):33
Functional characterization of GATA6 genetic variants associated with mild congenital heart defects.
Wu H, Wu H, He Y, Sun W, Meng Y, Wen B, Chu M
Biochemical and biophysical research communications 2023 Jan 22;641:77-83
Biochemical and biophysical research communications 2023 Jan 22;641:77-83
Antagonism among DUX family members evolved from an ancestral toxic single homeodomain protein.
Bosnakovski D, Toso EA, Ener ET, Gearhart MD, Yin L, Lüttmann FF, Magli A, Shi K, Kim J, Aihara H, Kyba M
bioRxiv : the preprint server for biology 2023 Jan 22;
bioRxiv : the preprint server for biology 2023 Jan 22;
Mitophagy Effects of Protodioscin on Human Osteosarcoma Cells by Inhibition of p38MAPK Targeting NIX/LC3 Axis.
Huang CF, Hsieh YH, Yang SF, Kuo CH, Wang PH, Liu CJ, Lin RC
Cells 2023 Jan 21;12(3)
Cells 2023 Jan 21;12(3)
Screening and identification of CNIH4 gene associated with cell proliferation in gastric cancer based on a large-scale CRISPR-Cas9 screening database DepMap.
Zhang H, Lin Y, Zhuang M, Zhu L, Dai Y, Lin M
Gene 2023 Jan 20;850:146961
Gene 2023 Jan 20;850:146961
Centrosomal protein 120 promotes centrosome amplification and gastric cancer progression via USP54-mediated deubiquitination of PLK4.
Zhang C, Ma X, Wei G, Zhu X, Hu P, Chen X, Wang D, Li Y, Ruan T, Zhang W, Tao K, Wu C
iScience 2023 Jan 20;26(1):105745
iScience 2023 Jan 20;26(1):105745
Alternative transcribed 3' isoform of long non-coding RNA Malat1 inhibits mouse retinal oxidative stress.
Ghanam AR, Ke S, Wang S, Elgendy R, Xie C, Wang S, Zhang R, Wei M, Liu W, Cao J, Zhang Y, Zhang Z, Xue T, Zheng Y, Song X
iScience 2023 Jan 20;26(1):105740
iScience 2023 Jan 20;26(1):105740
Marine-Derived Natural Product HDYL-GQQ-495 Targets P62 to Inhibit Autophagy.
Li Q, Fan J, Chen Y, Liu Y, Liu H, Jiang W, Li D, Dang Y
Marine drugs 2023 Jan 20;21(2)
Marine drugs 2023 Jan 20;21(2)
The Adipokine Visfatin Modulates Cancer Stem Cell Properties in Triple-Negative Breast Cancer.
Chiang YF, Huang KC, Chen HY, Huang TC, Ali M, Chang HY, Shieh TM, Shih YH, Wang KL, Huang YJ, Chung CP, Hsia SM
Biomedicines 2023 Jan 20;11(2)
Biomedicines 2023 Jan 20;11(2)
miR-214-5p/C1QTNF1 axis enhances PCV2 replication through promoting autophagy by targeting AKT/mTOR signaling pathway.
Cao Y, Jing P, Yu L, Wu Z, Gao S, Bao W
Virus research 2023 Jan 2;323:198990
Virus research 2023 Jan 2;323:198990
RPS24 Is Associated with a Poor Prognosis and Immune Infiltration in Hepatocellular Carcinoma.
Li H, Gao L, Kang X, Wang X, Yu Y, Zhang Y, Chen H
International journal of molecular sciences 2023 Jan 2;24(1)
International journal of molecular sciences 2023 Jan 2;24(1)
REC drives recombination to repair double-strand breaks in animal mtDNA.
Klucnika A, Mu P, Jezek J, McCormack M, Di Y, Bradshaw CR, Ma H
The Journal of cell biology 2023 Jan 2;222(1)
The Journal of cell biology 2023 Jan 2;222(1)
Hepatocyte growth factor-mediated apoptosis mechanisms of cytotoxic CD8(+) T cells in normal and cirrhotic livers.
Chen Q, Yan M, Lin H, Lai J, Yang Z, Hu D, Deng Y, Shi S, Shuai L, Zhang L, Zhang H, Bai L
Cell death discovery 2023 Jan 19;9(1):13
Cell death discovery 2023 Jan 19;9(1):13
Bacillus subtilis Modulated the Expression of Osteogenic Markers in a Human Osteoblast Cell Line.
Sojan JM, Licini C, Marcheggiani F, Carnevali O, Tiano L, Mattioli-Belmonte M, Maradonna F
Cells 2023 Jan 19;12(3)
Cells 2023 Jan 19;12(3)
Kaposi's sarcoma-associated herpesvirus induces specialised ribosomes to efficiently translate viral lytic mRNAs.
Murphy JC, Harrington EM, Schumann S, Vasconcelos EJR, Mottram TJ, Harper KL, Aspden JL, Whitehouse A
Nature communications 2023 Jan 18;14(1):300
Nature communications 2023 Jan 18;14(1):300
Driving axon regeneration by orchestrating neuronal and non-neuronal innate immune responses via the IFNγ-cGAS-STING axis.
Wang X, Yang C, Wang X, Miao J, Chen W, Zhou Y, Xu Y, An Y, Cheng A, Ye W, Chen M, Song D, Yuan X, Wang J, Qian P, Wu AR, Zhang ZY, Liu K
Neuron 2023 Jan 18;111(2):236-255.e7
Neuron 2023 Jan 18;111(2):236-255.e7
MiR-182 Is Upregulated in Prostate Cancer and Contributes to Tumor Progression by Targeting MITF.
Stafford MYC, McKenna DJ
International journal of molecular sciences 2023 Jan 17;24(3)
International journal of molecular sciences 2023 Jan 17;24(3)
Proteoglycan SPOCK1 as a Poor Prognostic Marker Promotes Malignant Progression of Clear Cell Renal Cell Carcinoma via Triggering the Snail/Slug-MMP-2 Axis-Mediated Epithelial-to-Mesenchymal Transition.
Lin YW, Wen YC, Hsiao CH, Lai FR, Yang SF, Yang YC, Ho KH, Hsieh FK, Hsiao M, Lee WJ, Chien MH
Cells 2023 Jan 17;12(3)
Cells 2023 Jan 17;12(3)
Discovery of IHMT-337 as a potent irreversible EZH2 inhibitor targeting CDK4 transcription for malignancies.
Mei H, Wu H, Yang J, Zhou B, Wang A, Hu C, Qi S, Jiang Z, Zou F, Wang B, Liu F, Chen Y, Wang W, Liu J, Liu Q
Signal transduction and targeted therapy 2023 Jan 16;8(1):18
Signal transduction and targeted therapy 2023 Jan 16;8(1):18
Niche stiffness sustains cancer stemness via TAZ and NANOG phase separation.
Liu X, Ye Y, Zhu L, Xiao X, Zhou B, Gu Y, Si H, Liang H, Liu M, Li J, Jiang Q, Li J, Yu S, Ma R, Su S, Liao JY, Zhao Q
Nature communications 2023 Jan 16;14(1):238
Nature communications 2023 Jan 16;14(1):238
CTNNAL1 enhances glucocorticoid sensitivity in HDM-induced asthma mouse model through deactivating hsp90 signaling pathway.
Wu D, Liu L, Zhu J, Liu C, Long C, Liu C, Qu X, Liu H, Ji M, Qin X, Xiang Y
Life sciences 2023 Jan 15;313:121304
Life sciences 2023 Jan 15;313:121304
TBK1 Isoform Inhibits Grass Carp Reovirus Infection by Targeting the Degradation of Viral Nonstructural Proteins NS80 and NS38.
Zhang J, Chang MX
Journal of immunology (Baltimore, Md. : 1950) 2023 Jan 15;210(2):191-203
Journal of immunology (Baltimore, Md. : 1950) 2023 Jan 15;210(2):191-203
The m6A demethylase FTO promotes keloid formation by up-regulating COL1A1.
Ren S, Ji Y, Wang M, Ye M, Huang L, Cai X
Annals of translational medicine 2023 Jan 15;11(1):15
Annals of translational medicine 2023 Jan 15;11(1):15
Prenatal Lipopolysaccharide Exposure Alters Hepatic Drug-Metabolizing Enzyme Expression in Mouse Offspring via Histone Modifications.
Zhu H, Liu G, Chang Q, Yan M, Yang K, Li Y, Nie Y, Li X, Han S, Wang P, Zhang L
Toxics 2023 Jan 15;11(1)
Toxics 2023 Jan 15;11(1)
Deficit of PKHD1L1 in the dentate gyrus increases seizure susceptibility in mice.
Yu J, Wang G, Chen Z, Wan L, Zhou J, Cai J, Liu X, Wang Y
Human molecular genetics 2023 Jan 13;32(3):506-519
Human molecular genetics 2023 Jan 13;32(3):506-519
RBM4 regulates cellular senescence via miR1244/SERPINE1 axis.
Wang L, Zhang X, Sheng J, Chen L, Zhi L, Zheng Q, Qi Y, Wang L, Zhang J, Zhao J, Wang Y, Liu SX, Sun MZ, Zhang W
Cell death & disease 2023 Jan 13;14(1):27
Cell death & disease 2023 Jan 13;14(1):27
Flavivirus prM interacts with MDA5 and MAVS to inhibit RLR antiviral signaling.
Sui L, Zhao Y, Wang W, Chi H, Tian T, Wu P, Zhang J, Zhao Y, Wei ZK, Hou Z, Zhou G, Wang G, Wang Z, Liu Q
Cell & bioscience 2023 Jan 13;13(1):9
Cell & bioscience 2023 Jan 13;13(1):9
New Monoterpenoid Indole Alkaloids from Tabernaemontana crassa Inhibit β-Amyloid42 Production and Phospho-Tau (Thr217).
Li S, Han LL, Huang KP, Ma YH, Guo LL, Guo Y, Ran X, Yao YG, Hao XJ, Luo R, Zhang Y
International journal of molecular sciences 2023 Jan 12;24(2)
International journal of molecular sciences 2023 Jan 12;24(2)
Metabolomics Profiles Reveal New Insights of Herpes Simplex Virus Type 1 Infection.
Huang P, Wang X, Lei M, Ma Y, Chen H, Sun J, Hu Y, Shi J
International journal of molecular sciences 2023 Jan 12;24(2)
International journal of molecular sciences 2023 Jan 12;24(2)
LncRNA-TBP mediates TATA-binding protein recruitment to regulate myogenesis and induce slow-twitch myofibers.
Ma M, Cai B, Zhou Z, Kong S, Zhang J, Xu H, Zhang X, Nie Q
Cell communication and signaling : CCS 2023 Jan 12;21(1):7
Cell communication and signaling : CCS 2023 Jan 12;21(1):7
Porphyromonas gingivalis bacteremia increases the permeability of the blood-brain barrier via the Mfsd2a/Caveolin-1 mediated transcytosis pathway.
Lei S, Li J, Yu J, Li F, Pan Y, Chen X, Ma C, Zhao W, Tang X
International journal of oral science 2023 Jan 12;15(1):3
International journal of oral science 2023 Jan 12;15(1):3
Crizotinib Nanomicelles Synergize with Chemotherapy through Inducing Proteasomal Degradation of Mutp53 Proteins.
Yi T, Qian J, Ye Y, Zhang H, Jin X, Wang M, Yang Z, Zhang W, Wen L, Zhang Y
ACS applied materials & interfaces 2023 Jan 11;15(1):511-523
ACS applied materials & interfaces 2023 Jan 11;15(1):511-523
Silencing of circCRIM1 Drives IGF2BP1-Mediated NSCLC Immune Evasion.
Peng W, Ye L, Xue Q, Wei X, Wang Z, Xiang X, Zhang S, Zhang P, Wang H, Zhou Q
Cells 2023 Jan 10;12(2)
Cells 2023 Jan 10;12(2)
Disrupted BRCA1-PALB2 interaction induces tumor immunosuppression and T-lymphocyte infiltration in HCC through cGAS-STING pathway.
Ma H, Kang Z, Foo TK, Shen Z, Xia B
Hepatology (Baltimore, Md.) 2023 Jan 1;77(1):33-47
Hepatology (Baltimore, Md.) 2023 Jan 1;77(1):33-47
Effects of apocynin on ISO-induced delayed afterdepolarizations in rat atrial myocytes and the underlying mechanisms.
Zhang N, Dan Q, Dong Y, Liu Y, Zhuang W, Xie Z, Zhao Q, Lin K, Li Y
Biochemical and biophysical research communications 2023 Jan 1;638:36-42
Biochemical and biophysical research communications 2023 Jan 1;638:36-42
Ablation of EWS-FLI1 by USP9X inhibition suppresses cancer cell growth in Ewing sarcoma.
Wang S, Huo X, Yang Y, Mo Y, Kollipara RK, Kittler R
Cancer letters 2023 Jan 1;552:215984
Cancer letters 2023 Jan 1;552:215984
Identification of circRNA expression profiles and the potential role of hsa_circ_0006916 in silicosis and pulmonary fibrosis.
Wu Q, Jiao B, Zhang Q, Jin C, Yu H, Wang F
Toxicology 2023 Jan 1;483:153384
Toxicology 2023 Jan 1;483:153384
Cnpy3(2xHA) mice reveal neuronal expression of Cnpy3 in the brain.
Islam MM, Mutoh H, Aoto K, Belal H, Saitsu H
Journal of neuroscience methods 2023 Jan 1;383:109730
Journal of neuroscience methods 2023 Jan 1;383:109730
Role and mechanism of the p-JAK2/p-STAT3 signaling pathway in follicular development in PCOS rats.
Wang H, Feng X, Wang T, Pan J, Zheng Z, Su Y, Weng H, Zhang L, Chen L, Zhou L, Zheng L
General and comparative endocrinology 2023 Jan 1;330:114138
General and comparative endocrinology 2023 Jan 1;330:114138
The activated ATM/AMPK/mTOR axis promotes autophagy in response to oxidative stress-mediated DNA damage co-induced by molybdenum and cadmium in duck testes.
Pu W, Chu X, Guo H, Huang G, Cui T, Huang B, Dai X, Zhang C
Environmental pollution (Barking, Essex : 1987) 2023 Jan 1;316(Pt 2):120574
Environmental pollution (Barking, Essex : 1987) 2023 Jan 1;316(Pt 2):120574
Large extracellular vesicles in bovine follicular fluid inhibit the apoptosis of granulosa cell and stimulate the production of steroid hormones.
Ying W, Yunqi Z, Zimeng L, Kangning X, Deji L, Chen Q, Yong Z, Fusheng Q
Theriogenology 2023 Jan 1;195:149-158
Theriogenology 2023 Jan 1;195:149-158
Dysfunctional microRNA-144-3p/ZBTB20/ERK/CREB1 signalling pathway is associated with MK-801-induced schizophrenia-like abnormalities.
Pan B, Han B, Zhu X, Wang Y, Ji H, Weng J, Liu Y
Brain research 2023 Jan 1;1798:148153
Brain research 2023 Jan 1;1798:148153
Integrated manganese (III)-doped nanosystem for optimizing photothermal ablation: Amplifying hyperthermia-induced STING pathway and enhancing antitumor immunity.
Xia J, Wang L, Shen T, Li P, Zhu P, Xie S, Chen Z, Zhou F, Zhang J, Ling J, Liu X, Yu H, Sun J
Acta biomaterialia 2023 Jan 1;155:601-617
Acta biomaterialia 2023 Jan 1;155:601-617
Liquiritin inhibits MRGPRX2-mediated pseudo-allergy through the PI3K/AKT and PLCγ signaling pathways.
Wang L, Huang C, Li Z, Hu G, Qi J, Fan Z
Heliyon 2023 Feb;9(2):e13290
Heliyon 2023 Feb;9(2):e13290
Ribosomal protein L31 (RPL31) inhibits the proliferation and migration of gastric cancer cells.
Wu F, Liu Y, Hu S, Lu C
Heliyon 2023 Feb;9(2):e13076
Heliyon 2023 Feb;9(2):e13076
MST4 as a novel therapeutic target for autophagy and radiosensitivity in gastric cancer.
Shi X, Zou J, Wang Y, Zhao J, Ye B, Qi Q, Liu F, Hu J, Li S, Tian Y
IUBMB life 2023 Feb;75(2):117-136
IUBMB life 2023 Feb;75(2):117-136
Chronic Microcystin-LR-Induced α-Synuclein Promotes Neuroinflammation Through Activation of the NLRP3 Inflammasome in Microglia.
Yan M, Jin H, Pan C, Han X
Molecular neurobiology 2023 Feb;60(2):884-900
Molecular neurobiology 2023 Feb;60(2):884-900
Intra-amniotic mesenchymal stem cell therapy improves the amniotic fluid microenvironment in rat spina bifida aperta fetuses.
Wei X, Ma W, Gu H, Liu D, Luo W, Cao S, Jia S, Huang T, He Y, Bai Y, Wang W, Yuan Z
Cell proliferation 2023 Feb;56(2):e13354
Cell proliferation 2023 Feb;56(2):e13354
Periplaneta Americana extract inhibits osteoclastic differentiation in vitro.
Zhao B, Zhang Y, Xu J, Li Y, Yuan Q, Zhou C
Cell proliferation 2023 Feb;56(2):e13341
Cell proliferation 2023 Feb;56(2):e13341
Early growth response 2 in the mPFC regulates mouse social and cooperative behaviors.
Zhang Y, Feng W, Wang Z, Pang Y, Jin Y, Chen S, Ding S, Wang T, Zou Y, Sun P, Chen Y, Feng H, Huang H, Sheng C, Xiao M
Lab animal 2023 Feb;52(2):37-50
Lab animal 2023 Feb;52(2):37-50
MicroRNA-588 regulates the invasive, migratory and vasculogenic mimicry-forming abilities of hypoxic glioma cells by targeting ROBO1.
Yu R, Zhao R, Sun X, Zhang Z, Wang S, Gao X, Sun Z, Xue H, Li G
Molecular biology reports 2023 Feb;50(2):1333-1347
Molecular biology reports 2023 Feb;50(2):1333-1347
Promoting effects of calponin 3 on the growth of diffuse large B‑cell lymphoma cells.
Xing X, Liu M, Wang X, Guo Q, Wang H
Oncology reports 2023 Feb;49(2)
Oncology reports 2023 Feb;49(2)
Novel naturally occurring autoantibodies attenuate α-synuclein pathology in a mouse model of Parkinson's disease.
Li Y, Wang T, Meng L, Jin L, Liu C, Liang Y, Ren L, Liu Y, Liu Y, Liu S, Li T, Liang Y, Chen X, Zhang Z
Neuropathology and applied neurobiology 2023 Feb;49(1):e12860
Neuropathology and applied neurobiology 2023 Feb;49(1):e12860
Disruption of the lung-gut-brain axis is responsible for cortex damage induced by pulmonary exposure to zinc oxide nanoparticles.
Zhang L, Zhang Y, Jiang X, Mao L, Xia Y, Fan Y, Li N, Jiang Z, Qin X, Jiang Y, Liu G, Qiu F, Zhang J, Zou Z, Chen C
Toxicology 2023 Feb;485:153390
Toxicology 2023 Feb;485:153390
PKMYT1 inhibits lung adenocarcinoma progression by abrogating AKT1 activity.
Wang S, Liu X, Zhou T, Li J, Lin Y, Zhou A, Huang J, Zhao J, Cai J, Cai X, Huang Y, Li X
Cellular oncology (Dordrecht, Netherlands) 2023 Feb;46(1):195-209
Cellular oncology (Dordrecht, Netherlands) 2023 Feb;46(1):195-209
Targeting ARHGEF12 promotes neuroblastoma differentiation, MYCN degradation, and reduces tumorigenicity.
Yang Y, Wang S, Cai J, Liang J, Zhang Y, Xie Y, Luo F, Tang J, Gao Y, Shen S, Feng H, Li Y
Cellular oncology (Dordrecht, Netherlands) 2023 Feb;46(1):133-143
Cellular oncology (Dordrecht, Netherlands) 2023 Feb;46(1):133-143
Deubiquitinating enzyme Josephin-2 stabilizes PHGDH to promote a cancer stem cell phenotype in hepatocellular carcinoma.
Wang Y, Li ZX, Wang JG, Li LH, Shen WL, Dang XW
Genes & genomics 2023 Feb;45(2):215-224
Genes & genomics 2023 Feb;45(2):215-224
Corynoline ameliorates dextran sulfate sodium-induced colitis in mice by modulating Nrf2/NF-κB pathway.
Zhang H, Lang W, Li S, Xu C, Wang X, Li Y, Zhang Z, Wu T, Feng M
Immunopharmacology and immunotoxicology 2023 Feb;45(1):26-34
Immunopharmacology and immunotoxicology 2023 Feb;45(1):26-34
14-3-3ζ inhibits maladaptive repair in renal tubules by regulating YAP and reduces renal interstitial fibrosis.
Wang TT, Wu LL, Wu J, Zhang LS, Shen WJ, Zhao YH, Liu JN, Fu B, Wang X, Li QG, Bai XY, Wang LQ, Chen XM
Acta pharmacologica Sinica 2023 Feb;44(2):381-392
Acta pharmacologica Sinica 2023 Feb;44(2):381-392
Perfluorooctane sulfonate promotes hepatic lipid accumulation and steatosis in high-fat diet mice through AMP-activated protein kinase/acetyl-CoA carboxylase (AMPK/ACC) pathway.
Ling J, Hua L, Qin Y, Gu T, Jiang S, Zhao J
Journal of applied toxicology : JAT 2023 Feb;43(2):312-322
Journal of applied toxicology : JAT 2023 Feb;43(2):312-322
High Level of Ubiquitin Conjugate Enzyme E2O Indicates Poor Prognosis of Patients with Hepatocellular Carcinoma.
Lan SY, Ding Y, Wang C, Fang J, Ren C, Liu JL, Kang H, Chang Y
Current medical science 2023 Feb;43(1):93-103
Current medical science 2023 Feb;43(1):93-103
M2-like macrophage-derived exosomes facilitate metastasis in non-small-cell lung cancer by delivering integrin αVβ3.
Huang L, Wang F, Wang X, Su C, Wu S, Yang C, Luo M, Zhang J, Fu L
MedComm 2023 Feb;4(1):e191
MedComm 2023 Feb;4(1):e191
Decreased thioredoxin reductase 3 expression promotes nickel-induced damage to cardiac tissue via activating oxidative stress-induced apoptosis and inflammation.
Liu Y, Ma W, Liu Q, Liu P, Qiao S, Xu L, Sun Y, Gai X, Zhang Z
Environmental toxicology 2023 Feb;38(2):436-450
Environmental toxicology 2023 Feb;38(2):436-450
PI3K/AKT/mTOR pathway mediated-cell cycle dysregulation contribute to malignant proliferation of mouse spermatogonia induced by microcystin-leucine arginine.
Du X, Liu H, Tian Z, Zhang S, Shi L, Wang Y, Guo X, Zhang B, Yuan S, Zeng X, Zhang H
Environmental toxicology 2023 Feb;38(2):343-358
Environmental toxicology 2023 Feb;38(2):343-358
Ubiquitin-specific protease 24 promotes EV71 infection by restricting K63-linked polyubiquitination of TBK1.
Zang L, Gu J, Yang X, Yuan Y, Guo H, Zhou W, Ma J, Chen Y, Wu Y, Zheng H, Shi W
Virologica Sinica 2023 Feb;38(1):75-83
Virologica Sinica 2023 Feb;38(1):75-83
The functional implication of ATF6α in castration-resistant prostate cancer cells.
Zhou H, Zhang T, Chen L, Cui F, Xu C, Peng J, Ma W, Huang J, Sheng X, Liu M, Zhao F
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Feb;37(2):e22758
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Feb;37(2):e22758
Renal transporter OAT1 and PPAR-α pathway co-contribute to icaritin-induced nephrotoxicity.
Wang D, Liu J, Chen X, Chen J, Zhao T, Du J, Wang C, Meng Q, Sun H, Wang F, Liu K, Wu J
Phytotherapy research : PTR 2023 Feb;37(2):549-562
Phytotherapy research : PTR 2023 Feb;37(2):549-562
3, 14, 19-Triacetyl Andrographolide alleviates the cognitive dysfunction of 3 × Tg-AD mice by inducing initiation and promoting degradation process of autophagy.
Zhang H, Xie X, Shi J, Zhao Q, Luo D, Hao J, Zhou Y, Han G, Pang X
Phytotherapy research : PTR 2023 Feb;37(2):410-423
Phytotherapy research : PTR 2023 Feb;37(2):410-423
m(6) A Reader YTHDF1-Targeting Engineered Small Extracellular Vesicles for Gastric Cancer Therapy via Epigenetic and Immune Regulation.
You Q, Wang F, Du R, Pi J, Wang H, Huo Y, Liu J, Wang C, Yu J, Yang Y, Zhu L
Advanced materials (Deerfield Beach, Fla.) 2023 Feb;35(8):e2204910
Advanced materials (Deerfield Beach, Fla.) 2023 Feb;35(8):e2204910
Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.
Cao YF, Xie L, Tong BB, Chu MY, Shi WQ, Li X, He JZ, Wang SH, Wu ZY, Deng DX, Zheng YQ, Li ZM, Xu XE, Liao LD, Cheng YW, Li LY, Xu LY, Li EM
Cell death and differentiation 2023 Feb;30(2):527-543
Cell death and differentiation 2023 Feb;30(2):527-543
Ferroptotic stress facilitates smooth muscle cell dedifferentiation in arterial remodelling by disrupting mitochondrial homeostasis.
Ji QX, Zeng FY, Zhou J, Wu WB, Wang XJ, Zhang Z, Zhang GY, Tong J, Sun DY, Zhang JB, Cao WX, Shen FM, Lu JJ, Li DJ, Wang P
Cell death and differentiation 2023 Feb;30(2):457-474
Cell death and differentiation 2023 Feb;30(2):457-474
ARID2 mitigates hepatic steatosis via promoting the ubiquitination of JAK2.
Cao HJ, Jiang H, Ding K, Qiu XS, Ma N, Zhang FK, Wang YK, Zheng QW, Xia J, Ni QZ, Xu S, Zhu B, Ding XF, Chen TW, Qiu L, Chen W, Li ZG, Zhou B, Feng WM, Xie D, Li JJ
Cell death and differentiation 2023 Feb;30(2):383-396
Cell death and differentiation 2023 Feb;30(2):383-396
Protein engineering reveals that gasdermin A preferentially targets mitochondrial membranes over the plasma membrane during pyroptosis.
Kondolf HC, D'Orlando DA, Dubyak GR, Abbott DW
The Journal of biological chemistry 2023 Feb;299(2):102908
The Journal of biological chemistry 2023 Feb;299(2):102908
Disruption of the interaction between mutationally activated Gα(q) and Gβγ attenuates aberrant signaling.
Aumiller JL, Wedegaertner PB
The Journal of biological chemistry 2023 Feb;299(2):102880
The Journal of biological chemistry 2023 Feb;299(2):102880
Mitochondria-localized lncRNA HITT inhibits fusion by attenuating formation of mitofusin-2 homotypic or heterotypic complexes.
Wang X, Zhang Y, Lin Q, Zhao K, Zhu D, Hu Y
The Journal of biological chemistry 2023 Feb;299(2):102825
The Journal of biological chemistry 2023 Feb;299(2):102825
Antidepression of Xingpijieyu formula targets gut microbiota derived from depressive disorder.
Li Y, Yang L, Li J, Gao W, Zhao Z, Dong K, Duan W, Dai B, Guo R
CNS neuroscience & therapeutics 2023 Feb;29(2):669-681
CNS neuroscience & therapeutics 2023 Feb;29(2):669-681
Loss of TDP-43 function underlies hippocampal and cortical synaptic deficits in TDP-43 proteinopathies.
Ni J, Ren Y, Su T, Zhou J, Fu C, Lu Y, Li D, Zhao J, Li Y, Zhang Y, Fang Y, Liu N, Geng Y, Chen Y
Molecular psychiatry 2023 Feb;28(2):931-945
Molecular psychiatry 2023 Feb;28(2):931-945
NRP1 contributes to stemness and potentiates radioresistance via WTAP-mediated m6A methylation of Bcl-2 mRNA in breast cancer.
Wang Y, Zhang L, Sun XL, Lu YC, Chen S, Pei DS, Zhang LS
Apoptosis : an international journal on programmed cell death 2023 Feb;28(1-2):233-246
Apoptosis : an international journal on programmed cell death 2023 Feb;28(1-2):233-246
Ubiquitin D promotes the progression of rheumatoid arthritis via activation of the p38 MAPK pathway.
Chen H, Tao L, Liang J, Pan C, Wei H
Molecular medicine reports 2023 Feb;27(2)
Molecular medicine reports 2023 Feb;27(2)
An angiogenesis‑related lncRNA signature for the prognostic prediction of patients with bladder cancer and LINC02321 promotes bladder cancer progression via the VEGFA signaling pathway.
Kang Z, Dou Q, Huang T, Tu M, Zhong Y, Wang M, Li T
Molecular medicine reports 2023 Feb;27(2)
Molecular medicine reports 2023 Feb;27(2)
Aging-accelerated differential production and aggregation of STAT3 protein in neuronal cells and neural stem cells in the male mouse spinal cord.
Zhao T, Liu C, Liu L, Wang X, Liu C
Biogerontology 2023 Feb;24(1):137-148
Biogerontology 2023 Feb;24(1):137-148
Hypoxia-responsive covalent organic framework by single NIR laser-triggered for multimodal synergistic therapy of triple-negative breast cancer.
Han Z, Qian Y, Gao X, Yang D, Cai Y, Chen Y, Jin J, Yang Z
Colloids and surfaces. B, Biointerfaces 2023 Feb;222:113094
Colloids and surfaces. B, Biointerfaces 2023 Feb;222:113094
Hyaluronic acid mediated Fe(3)O(4) nanocubes reversing the EMT through targeted cancer stem cell.
Wang Y, Ma S, Liu X, Wei Y, Xu H, Liang Z, Hu Y, Lian X, Huang D
Colloids and surfaces. B, Biointerfaces 2023 Feb;222:113071
Colloids and surfaces. B, Biointerfaces 2023 Feb;222:113071
Exploration the role of INHBA in Hu sheep granulosa cells using RNA-Seq.
Bao Y, Li X, El-Samahy MA, Yang H, Wang Z, Yang F, Yao X, Wang F
Theriogenology 2023 Feb;197:198-208
Theriogenology 2023 Feb;197:198-208
Protective effect of human umbilical cord mesenchymal stem cell derived conditioned medium in a mutant TDP-43 induced motoneuron-like cellular model of ALS.
Lan J, Zhou Y, Wang H, Tang J, Kang Y, Wang P, Liu X, Peng Y
Brain research bulletin 2023 Feb;193:106-116
Brain research bulletin 2023 Feb;193:106-116
PBX1-SIRT1 Positive Feedback Loop Attenuates ROS-Mediated HF-MSC Senescence and Apoptosis.
Wang Y, Sui Y, Niu Y, Liu D, Xu Q, Liu F, Zuo K, Liu M, Sun W, Wang Z, Liu Z, Zou F, Shi J, Liu X, Liu J
Stem cell reviews and reports 2023 Feb;19(2):443-454
Stem cell reviews and reports 2023 Feb;19(2):443-454
Id4 modulates salivary gland homeostasis and its expression is downregulated in IgG4-related disease via miR-486-5p.
Hayashi Y, Kimura S, Yano E, Yoshimoto S, Saeki A, Yasukochi A, Hatakeyama Y, Moriyama M, Nakamura S, Jimi E, Kawakubo-Yasukochi T
Biochimica et biophysica acta. Molecular cell research 2023 Feb;1870(2):119404
Biochimica et biophysica acta. Molecular cell research 2023 Feb;1870(2):119404
Smart nanostructures for targeted oxygen-producing photodynamic therapy of skin photoaging and potential mechanism.
Wang Y, Lu Z, Huang Y, Jia W, Wang W, Zhang X, Chen C, Li Y, Yang C, Jiang G
Nanomedicine (London, England) 2023 Feb;18(3):217-231
Nanomedicine (London, England) 2023 Feb;18(3):217-231
Barrier-penetrating liposome targeted delivery of basic fibroblast growth factor for spinal cord injury repair.
Wu F, Wang P, Wei X, Yang Y, Al Mamun A, Zhang X, Zhu Y, Mo T, Zhang H, Jiang C, Hu J, Xiao J
Materials today. Bio 2023 Feb;18:100546
Materials today. Bio 2023 Feb;18:100546
Melatonin alleviates BDE-209-induced cognitive impairment and hippocampal neuroinflammation by modulating microglia polarization via SIRT1-mediated HMGB1/TLR4/NF-κB pathway.
Wu J, Hao Z, Wang Y, Yan D, Meng J, Ma H
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2023 Feb;172:113561
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2023 Feb;172:113561
GDF15 negatively regulates chemosensitivity via TGFBR2-AKT pathway-dependent metabolism in esophageal squamous cell carcinoma.
Du Y, Ma Y, Zhu Q, Fu Y, Li Y, Zhang Y, Li M, Feng F, Yuan P, Wang X
Frontiers of medicine 2023 Feb;17(1):119-131
Frontiers of medicine 2023 Feb;17(1):119-131
SPON2 promotes the bone metastasis of lung adenocarcinoma via activation of the NF-κB signaling pathway.
Wu M, Kong D, Zhang Y
Bone 2023 Feb;167:116630
Bone 2023 Feb;167:116630
Decreased expression and DNA hypermethylation of syncytin-1 in human villus tissues with unexplained recurrent spontaneous abortion.
Fu Y, Song Y, Zhang J, Wei LP, Sun XR
Journal of reproductive immunology 2023 Feb;155:103784
Journal of reproductive immunology 2023 Feb;155:103784
Capsaicin alleviates cisplatin-induced muscle loss and atrophy in vitro and in vivo.
Huang KC, Chiang YF, Huang TC, Chen HY, Lin PH, Ali M, Hsia SM
Journal of cachexia, sarcopenia and muscle 2023 Feb;14(1):182-197
Journal of cachexia, sarcopenia and muscle 2023 Feb;14(1):182-197
Chemical constituents from the stems and leaves of Amomum villosum Lour. and their anti-inflammatory and antioxidant activities.
Gao C, Zhu M, Xu W, Wang Y, Xiong L, Sun D, Sun M, Lin Y, Li H, Chen L
Bioorganic chemistry 2023 Feb;131:106281
Bioorganic chemistry 2023 Feb;131:106281
Honokiol alleviated neurodegeneration by reducing oxidative stress and improving mitochondrial function in mutant SOD1 cellular and mouse models of amyotrophic lateral sclerosis.
Zhou Y, Tang J, Lan J, Zhang Y, Wang H, Chen Q, Kang Y, Sun Y, Feng X, Wu L, Jin H, Chen S, Peng Y
Acta pharmaceutica Sinica. B 2023 Feb;13(2):577-597
Acta pharmaceutica Sinica. B 2023 Feb;13(2):577-597
Vaspin accelerates the proliferation, invasion and metastasis of Triple-Negative breast cancer through MiR-33a-5p/ABHD2.
Cao XH, Chen X, Yang K, Wang YL, Liang MX, Fei YJ, Tang JH
Cancer medicine 2023 Feb;12(4):4530-4542
Cancer medicine 2023 Feb;12(4):4530-4542
ITGA5 and ITGB1 contribute to Sorafenib resistance by promoting vasculogenic mimicry formation in hepatocellular carcinoma.
Shi Y, Shang J, Li Y, Zhong D, Zhang Z, Yang Q, Lai C, Feng T, Yao Y, Huang X
Cancer medicine 2023 Feb;12(3):3786-3796
Cancer medicine 2023 Feb;12(3):3786-3796
WWOX activates autophagy to alleviate lipopolysaccharide-induced acute lung injury by regulating mTOR.
Wang C, Yang Y, Zhou C, Mei X, Liu J, Luo K, Zhou J, Qin C, Zeng Z
International immunopharmacology 2023 Feb;115:109671
International immunopharmacology 2023 Feb;115:109671
Matrix metalloproteinase-21 promotes metastasis via increasing the recruitment and M2 polarization of macrophages in HCC.
Zhou J, Liu L, Hu X, Feng R, Zhao N, Zhang L, Hu W, Zhang J, Huang S, Liu L, Li W, Shan Y, Jin J
Cancer science 2023 Feb;114(2):423-435
Cancer science 2023 Feb;114(2):423-435
α-Synuclein induces Th17 differentiation and impairs the function and stability of Tregs by promoting RORC transcription in Parkinson's disease.
Li J, Zhao J, Chen L, Gao H, Zhang J, Wang D, Zou Y, Qin Q, Qu Y, Li J, Xiong Y, Min Z, Yan M, Mao Z, Xue Z
Brain, behavior, and immunity 2023 Feb;108:32-44
Brain, behavior, and immunity 2023 Feb;108:32-44
Omega-3 polyunsaturated fatty acids inhibit cardiomyocyte apoptosis and attenuate sepsis-induced cardiomyopathy.
Chen ZS, Yu MM, Wang K, Meng XL, Liu YC, Shou ST, Chai YF
Nutrition (Burbank, Los Angeles County, Calif.) 2023 Feb;106:111886
Nutrition (Burbank, Los Angeles County, Calif.) 2023 Feb;106:111886
Functional and miRNA regulatory characteristics of INSIG genes highlight the key role of lipid synthesis in the liver of chicken (Gallus gallus).
Yue Y, Liu Z, Zhang K, Jia Q, Wang D, Wang Z, Guo Y, Li D, Jiang R, Li Z, Tian Y, Kang X, Liu X, Li H
Poultry science 2023 Feb;102(2):102380
Poultry science 2023 Feb;102(2):102380
Manipulation of PD-L1 Endosomal Trafficking Promotes Anticancer Immunity.
Ye Z, Xiong Y, Peng W, Wei W, Huang L, Yue J, Zhang C, Lin G, Huang F, Zhang L, Zheng S, Yue J
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Feb;10(6):e2206411
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Feb;10(6):e2206411
Loss-of-Function of p21-Activated Kinase 2 Links BMP Signaling to Neural Tube Patterning Defects.
Wang Y, Zhang K, Guo J, Yang S, Shi X, Pan J, Sun Z, Zou J, Li Y, Li Y, Fan T, Song W, Cheng F, Zeng C, Li J, Zhang T, Sun ZS
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Feb;10(4):e2204018
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Feb;10(4):e2204018
Non-Lethal Concentrations of CdCl(2) Cause Marked Alternations in Cellular Stress Responses within Exposed Sertoli Cell Line.
Man Y, Liu Y, Xiong C, Zhang Y, Zhang L
Toxics 2023 Feb 9;11(2)
Toxics 2023 Feb 9;11(2)
Neddylation of EphB1 Regulates Its Activity and Associates with Liver Fibrosis.
Li R, Zhang D, Han Y, Chen K, Guo W, Chen Y, Wang S
International journal of molecular sciences 2023 Feb 8;24(4)
International journal of molecular sciences 2023 Feb 8;24(4)
Double Blast Wave Primary Effect on Synaptic, Glymphatic, Myelin, Neuronal and Neurovascular Markers.
Iacono D, Murphy EK, Stimpson CD, Leonessa F, Perl DP
Brain sciences 2023 Feb 8;13(2)
Brain sciences 2023 Feb 8;13(2)
RRP15 deficiency induces ribosome stress to inhibit colorectal cancer proliferation and metastasis via LZTS2-mediated β-catenin suppression.
Dong Z, Li J, Dai W, Yu D, Zhao Y, Liu S, Li X, Zhang Z, Zhang R, Liang X, Kong Q, Jin S, Jiang H, Jiang W, Ding C
Cell death & disease 2023 Feb 7;14(2):89
Cell death & disease 2023 Feb 7;14(2):89
Effect of CUX1 on the Proliferation of Hu Sheep Dermal Papilla Cells and on the Wnt/β-Catenin Signaling Pathway.
Zhou H, Huang S, Lv X, Wang S, Cao X, Yuan Z, Getachew T, Mwacharo JM, Haile A, Quan K, Li Y, Reverter A, Sun W
Genes 2023 Feb 7;14(2)
Genes 2023 Feb 7;14(2)
Microglia participate in postoperative cognitive dysfunction by mediating the loss of inhibitory synapse through the complement pathway.
Tan X, Wang J, Yao J, Yuan J, Dai Y, Sun M, Zhang T, Yang J, Cai W, Qiu L, Sun J
Neuroscience letters 2023 Feb 6;796:137049
Neuroscience letters 2023 Feb 6;796:137049
α-Tubulin detyrosination links the suppression of MCAK activity with taxol cytotoxicity.
Lopes D, Seabra AL, Orr B, Maiato H
The Journal of cell biology 2023 Feb 6;222(2)
The Journal of cell biology 2023 Feb 6;222(2)
Daphnetin Improves Neuropathic Pain by Inhibiting the Expression of Chemokines and Inflammatory Factors in the Spinal Cord and Interfering with Glial Cell Polarization.
Zhang T, Liang W, Zhang M, Cui S, Huang X, Ou W, Huang R, Gao J, Jia Z, Zhang S
Pharmaceuticals (Basel, Switzerland) 2023 Feb 6;16(2)
Pharmaceuticals (Basel, Switzerland) 2023 Feb 6;16(2)
Single-cell transcriptome analysis identifies Versican(+) myofibroblast as a hallmark for thoracic aortic aneurysm marked by activation of PI3K-AKT signaling pathway.
Song W, Qin L, Chen Y, Chen J, Wei L
Biochemical and biophysical research communications 2023 Feb 5;643:175-185
Biochemical and biophysical research communications 2023 Feb 5;643:175-185
Epigenetic Regulation of miR-25 and Lnc107153 on Expression of Seasonal Estrus Key Gene CHGA in Sheep.
Di R, Fan Y, He X, Liu Q, Wang X, Gong Y, Mwacharo JM, Wei C, Liu Y, Chu M
Biology 2023 Feb 4;12(2)
Biology 2023 Feb 4;12(2)
Isorhamnetin protects porcine oocytes from zearalenone-induced reproductive toxicity through the PI3K/Akt signaling pathway.
Li X, Duan J, Wang S, Cheng J, Chen H, Zhang Z, Yang L, Hua R, Li Q
Journal of animal science and biotechnology 2023 Feb 3;14(1):22
Journal of animal science and biotechnology 2023 Feb 3;14(1):22
Upregulated GPRC5A disrupting the Hippo pathway promotes the proliferation and migration of pancreatic cancer cells via the cAMP-CREB axis.
Fang W, Yu X, Deng J, Yu B, Xiong J, Ma M
Discover oncology 2023 Feb 3;14(1):17
Discover oncology 2023 Feb 3;14(1):17
Increased expression of glucagon-like peptide-1 and cystic fibrosis transmembrane conductance regulator in the ileum and colon in mouse treated with metformin.
Mizoguchi M, Takemori H, Furukawa S, Ito M, Asai M, Morino H, Miura T, Yabe D, Shibata T
Endocrine journal 2023 Feb 28;70(2):149-159
Endocrine journal 2023 Feb 28;70(2):149-159
The pseudogene DUXAP10 contributes to gefitinib resistance in NSCLC by repressing OAS2 expression.
Ren S, Zhu Y, Wang S, Zhang Q, Zhang N, Zou X, Wei C, Wang Z
Acta biochimica et biophysica Sinica 2023 Feb 28;55(1):81-90
Acta biochimica et biophysica Sinica 2023 Feb 28;55(1):81-90
Cofilin promotes tau pathology in Alzheimer's disease.
Yan M, Tang L, Dai L, Lei C, Xiong M, Zhang X, He M, Tian Y, Xiong J, Ke W, Zhang Z, Zhang C, Deng X, Zhang Z
Cell reports 2023 Feb 28;42(2):112138
Cell reports 2023 Feb 28;42(2):112138
Negative regulation of TREM2-mediated C9orf72 poly-GA clearance by the NLRP3 inflammasome.
Shu X, Wei C, Tu WY, Zhong K, Qi S, Wang A, Bai L, Zhang SX, Luo B, Xu ZZ, Zhang K, Shen C
Cell reports 2023 Feb 28;42(2):112133
Cell reports 2023 Feb 28;42(2):112133
Synergistic Effect of Hydrogen and 5-Aza on Myogenic Differentiation through the p38 MAPK Signaling Pathway in Adipose-Derived Mesenchymal Stem Cells.
Fei W, Pang E, Hou L, Dai J, Liu M, Wang X, Xie B, Wang J
International journal of stem cells 2023 Feb 28;16(1):78-92
International journal of stem cells 2023 Feb 28;16(1):78-92
Mesenchymal Stem Cells Ameliorate Fibrosis by Enhancing Autophagy via Inhibiting Galectin-3/Akt/mTOR Pathway and by Alleviating the EMT via Inhibiting Galectin-3/Akt/GSK3β/Snail Pathway in NRK-52E Fibrosis.
Zhao Y, Guo C, Zeng L, Li J, Liu X, Wang Y, Zhao K, Chen B
International journal of stem cells 2023 Feb 28;16(1):52-65
International journal of stem cells 2023 Feb 28;16(1):52-65
Supplementation with α-ketoglutarate improved the efficacy of anti-PD1 melanoma treatment through epigenetic modulation of PD-L1.
Liu N, Zhang J, Yan M, Chen L, Wu J, Tao Q, Yan B, Chen X, Peng C
Cell death & disease 2023 Feb 28;14(2):170
Cell death & disease 2023 Feb 28;14(2):170
Knockdown of MEF2D inhibits the development and progression of B-cell acute lymphoblastic leukemia.
Chang N, Feng J, Liao P, Hu Y, Li M, He Y, Li Y
Translational cancer research 2023 Feb 28;12(2):287-300
Translational cancer research 2023 Feb 28;12(2):287-300
The upregulation of peripheral blood polyamine metabolites spermidine and spermine in children with hand, foot, mouth disease is related to enterovirus 71 capsid protein VP1, but not VP4.
Li C, Zhang W, Chang X, Di X, Xie Q, Lin B, Zhang H, Ye Z, Lan M, Lian J, Zhang H, Qiu X, Zeng J, Huang M
Translational pediatrics 2023 Feb 28;12(2):194-207
Translational pediatrics 2023 Feb 28;12(2):194-207
Rab8a as a mitochondrial receptor for lipid droplets in skeletal muscle.
Ouyang Q, Chen Q, Ke S, Ding L, Yang X, Rong P, Feng W, Cao Y, Wang Q, Li M, Su S, Wei W, Liu M, Liu J, Zhang X, Li JZ, Wang HY, Chen S
Developmental cell 2023 Feb 27;58(4):289-305.e6
Developmental cell 2023 Feb 27;58(4):289-305.e6
Cdh5-mediated Fpn1 deletion exerts neuroprotective effects during the acute phase and inhibitory effects during the recovery phase of ischemic stroke.
Zheng H, Guo X, Kang S, Li Z, Tian T, Li J, Wang F, Yu P, Chang S, Chang YZ
Cell death & disease 2023 Feb 25;14(2):161
Cell death & disease 2023 Feb 25;14(2):161
Cell-type-specific regulation of APOE levels in human neurons by the Alzheimer's disease risk gene SORL1.
Lee H, Aylward AJ, Pearse RV, Hsieh YC, Augur ZM, Benoit CR, Chou V, Knupp A, Pan C, Goberdhan S, Duong DM, Seyfried NT, Bennett DA, Klein HU, De Jager PL, Menon V, Young JE, Young-Pearse TL
bioRxiv : the preprint server for biology 2023 Feb 25;
bioRxiv : the preprint server for biology 2023 Feb 25;
TNF-α contributes to sarcopenia through caspase-8/caspase-3/GSDME-mediated pyroptosis.
Wu J, Lin S, Chen W, Lian G, Wu W, Chen A, Sagor MIH, Luo L, Wang H, Xie L
Cell death discovery 2023 Feb 24;9(1):76
Cell death discovery 2023 Feb 24;9(1):76
Stimulation of Hepatic Ferritinophagy Mitigates Irp2 Depletion-Induced Anemia.
Liu Y, Li Y, Yang L, Shen J, Zhao H, Dong W, Chang Y, Qiao T, Li K
Antioxidants (Basel, Switzerland) 2023 Feb 24;12(3)
Antioxidants (Basel, Switzerland) 2023 Feb 24;12(3)
Protective Potential of β-Hydroxybutyrate against Glucose-Deprivation-Induced Neurotoxicity Involving the Modulation of Autophagic Flux and the Monomeric Aβ Level in Neuro-2a Cells.
Chiang YF, Nguyen NTK, Hsia SM, Chen HY, Lin SH, Lin CI
Biomedicines 2023 Feb 24;11(3)
Biomedicines 2023 Feb 24;11(3)
RhoGDIα regulates spermatogenesis through Rac1/cofilin/F-actin signaling.
Zhu H, Wen Z, Zhang A, Liu D, Wang H, Cheng Y, Yang X, Xiao Y, Li J, Sun D, Wu B, Gao J
Communications biology 2023 Feb 23;6(1):214
Communications biology 2023 Feb 23;6(1):214
Comparison of human PEX knockout cell lines suggests a dual role of PEX1 in peroxisome biogenesis.
Ott J, Sehr J, Schmidt N, Schliebs W, Erdmann R
Biological chemistry 2023 Feb 23;404(2-3):209-219
Biological chemistry 2023 Feb 23;404(2-3):209-219
Comprehensive landscape of immune-based classifier related to early diagnosis and macrophage M1 in spinal cord injury.
Zhang Z, Zhu Z, Wang X, Liu D, Liu X, Mi Z, Tao H, Fan H
Aging 2023 Feb 23;15(4):1158-1176
Aging 2023 Feb 23;15(4):1158-1176
THADA inhibition in mice protects against type 2 diabetes mellitus by improving pancreatic β-cell function and preserving β-cell mass.
Zhang Y, Han S, Liu C, Zheng Y, Li H, Gao F, Bian Y, Liu X, Liu H, Hu S, Li Y, Chen ZJ, Zhao S, Zhao H
Nature communications 2023 Feb 23;14(1):1020
Nature communications 2023 Feb 23;14(1):1020
PAK2 is essential for chromosome alignment in metaphase I oocytes.
Zeng J, Wang S, Gao M, Lu D, Song S, Chen D, Fan W, Xu Z, Zhang Z, Sun X
Cell death & disease 2023 Feb 22;14(2):150
Cell death & disease 2023 Feb 22;14(2):150
Skeletal dysplasia-causing TRPV4 mutations suppress the hypertrophic differentiation of human iPSC-derived chondrocytes.
Dicks AR, Maksaev GI, Harissa Z, Savadipour A, Tang R, Steward N, Liedtke W, Nichols CG, Wu CL, Guilak F
eLife 2023 Feb 22;12
eLife 2023 Feb 22;12
Single-cell transcriptomic dissection of the cellular and molecular events underlying the triclosan-induced liver fibrosis in mice.
Bai YM, Yang F, Luo P, Xie LL, Chen JH, Guan YD, Zhou HC, Xu TF, Hao HW, Chen B, Zhao JH, Liang CL, Dai LY, Geng QS, Wang JG
Military Medical Research 2023 Feb 22;10(1):7
Military Medical Research 2023 Feb 22;10(1):7
METTL14-dependent maturation of pri-miR-17 regulates mitochondrial homeostasis and induces chemoresistance in colorectal cancer.
Sun K, Chen L, Li Y, Huang B, Yan Q, Wu C, Lai Q, Fang Y, Cai J, Liu Y, Chen J, Wang X, Zhu Y, Dong S, Tan J, Li A, Liu S, Zhang Y
Cell death & disease 2023 Feb 21;14(2):148
Cell death & disease 2023 Feb 21;14(2):148
Mutation in Smek2 regulating hepatic glucose metabolism causes hypersarcosinemia and hyperhomocysteinemia in rats.
Tanaka Y, Kawano M, Nakashima S, Yamaguchi C, Asahina M, Sakamoto M, Shirouchi B, Tashiro K, Imaizumi K, Sato M
Scientific reports 2023 Feb 21;13(1):3053
Scientific reports 2023 Feb 21;13(1):3053
Infralimbic YTHDF1 is necessary for the beneficial effects of acute mild exercise on auditory fear extinction retention.
Li SJ, Zhang LX, Zou GJ, Ma MH, Zhou SF, Lu XY, Li F, Li CQ
Cerebral cortex (New York, N.Y. : 1991) 2023 Feb 20;33(5):1814-1825
Cerebral cortex (New York, N.Y. : 1991) 2023 Feb 20;33(5):1814-1825
Pro-fibrotic and apoptotic activities of circARAP1 in myocardial ischemia-reperfusion injury.
Li X, Guo L, Wang J, Yang X
European journal of medical research 2023 Feb 20;28(1):84
European journal of medical research 2023 Feb 20;28(1):84
BMAL1/p53 mediating bronchial epithelial cell autophagy contributes to PM2.5-aggravated asthma.
Chen SJ, Huang Y, Yu F, Feng X, Zheng YY, Li Q, Niu Q, Jiang YH, Zhao LQ, Wang M, Cheng PP, Song LJ, Liang LM, He XL, Xiong L, Xiang F, Wang X, Ma WL, Ye H
Cell communication and signaling : CCS 2023 Feb 20;21(1):39
Cell communication and signaling : CCS 2023 Feb 20;21(1):39
Iron overload modulates follicular microenvironment via ROS/HIF-1α/FSHR signaling.
Wu Y, Yang R, Lan J, Wu Y, Huang J, Fan Q, You Y, Lin H, Jiao X, Chen H, Cao C, Zhang Q
Free radical biology & medicine 2023 Feb 20;196:37-52
Free radical biology & medicine 2023 Feb 20;196:37-52
Serine hydroxymethyltransferase 2 knockdown induces apoptosis in ccRCC by causing lysosomal membrane permeabilization via metabolic reprogramming.
Liu Z, Fan M, Hou J, Pan S, Xu Y, Zhang H, Liu C, Hao X, Li X, Wang H
Cell death & disease 2023 Feb 20;14(2):144
Cell death & disease 2023 Feb 20;14(2):144
TIM-4 orchestrates mitochondrial homeostasis to promote lung cancer progression via ANXA2/PI3K/AKT/OPA1 axis.
Wang Y, Wang Y, Liu W, Ding L, Zhang X, Wang B, Tong Z, Yue X, Li C, Xu L, Wu Z, Liang X, Ma C, Gao L
Cell death & disease 2023 Feb 20;14(2):141
Cell death & disease 2023 Feb 20;14(2):141
Rumen-protected glucose stimulates the secretion of reproductive hormones and the mTOR/AKT signaling pathway in the ovaries of early postpartum.
Wang Y, Jin C, Yi Y, Hu Y, Han X, Tan Z, Wang Z, Kang J
Scientific reports 2023 Feb 20;13(1):2940
Scientific reports 2023 Feb 20;13(1):2940
L-Ascorbic Acid 2-Phosphate Attenuates Methylmercury-Induced Apoptosis by Inhibiting Reactive Oxygen Species Accumulation and DNA Damage in Human SH-SY5Y Cells.
Zuo K, Xu Q, Wang Y, Sui Y, Niu Y, Liu Z, Liu M, Liu X, Liu D, Sun W, Wang Z, Liu X, Liu J
Toxics 2023 Feb 2;11(2)
Toxics 2023 Feb 2;11(2)
Ferroptosis Inducers Kill Mesenchymal Stem Cells Affected by Neuroblastoma.
Li X, Wang Q, Xu C, Zhang L, Zhou J, Lv J, Xu M, Jiang D
Cancers 2023 Feb 18;15(4)
Cancers 2023 Feb 18;15(4)
B-lymphoid tyrosine kinase-mediated FAM83A phosphorylation elevates pancreatic tumorigenesis through interacting with β-catenin.
Zhou C, Zhu X, Liu N, Dong X, Zhang X, Huang H, Tang Y, Liu S, Hu M, Wang M, Deng X, Li S, Zhang R, Huang Y, Lyu H, Xiao S, Luo S, Ali DW, Michalak M, Chen XZ, Wang Z, Tang J
Signal transduction and targeted therapy 2023 Feb 17;8(1):66
Signal transduction and targeted therapy 2023 Feb 17;8(1):66
High glucose-induced glucagon resistance and membrane distribution of GCGR revealed by super-resolution imaging.
Gao J, Li H, Xu H, Liu Y, Cai M, Shi Y, Zhang J, Wang H
iScience 2023 Feb 17;26(2):105967
iScience 2023 Feb 17;26(2):105967
Mulberroside A alleviates osteoarthritis via restoring impaired autophagy and suppressing MAPK/NF-κB/PI3K-AKT-mTOR signaling pathways.
Lu R, Wei Z, Wang Z, Xu S, Sun K, Cheng P, Huang X, You H, Guo F, Liang S, Chen AM
iScience 2023 Feb 17;26(2):105936
iScience 2023 Feb 17;26(2):105936
WWP2 drives the progression of gastric cancer by facilitating the ubiquitination and degradation of LATS1 protein.
Zou J, Zhou L, Le Y, Fang Z, Zhong M, Nie F, Wei X, Zhang X, Chen Z, Cai L, Wang H, Xiong J, Fang Z, Xiang X
Cell communication and signaling : CCS 2023 Feb 17;21(1):38
Cell communication and signaling : CCS 2023 Feb 17;21(1):38
Chemical Proteomics with Novel Fully Functionalized Fragments and Stringent Target Prioritization Identifies the Glutathione-Dependent Isomerase GSTZ1 as a Lung Cancer Target.
Liao Y, Chin Chan S, Welsh EA, Fang B, Sun L, Schönbrunn E, Koomen JM, Duckett DR, Haura EB, Monastyrskyi A, Rix U
ACS chemical biology 2023 Feb 17;18(2):251-264
ACS chemical biology 2023 Feb 17;18(2):251-264
Amino acid substitutions in norovirus VP1 dictate cell tropism via an attachment process dependent on membrane mobility.
Mills JT, Minogue SC, Snowden JS, Arden WKC, Rowlands DJ, Stonehouse NJ, Wobus CE, Herod MR
bioRxiv : the preprint server for biology 2023 Feb 17;
bioRxiv : the preprint server for biology 2023 Feb 17;
N(6)-methyladenosine modification in 18S rRNA promotes tumorigenesis and chemoresistance via HSF4b/HSP90B1/mutant p53 axis.
Chen B, Huang Y, He S, Yu P, Wu L, Peng H
Cell chemical biology 2023 Feb 16;30(2):144-158.e10
Cell chemical biology 2023 Feb 16;30(2):144-158.e10
The Alpha-1 Subunit of the Na(+)/K(+)-ATPase (ATP1A1) Is a Host Factor Involved in the Attachment of Porcine Epidemic Diarrhea Virus.
Xiong M, Liu X, Liang T, Ban Y, Liu Y, Zhang L, Xu Z, Song C
International journal of molecular sciences 2023 Feb 16;24(4)
International journal of molecular sciences 2023 Feb 16;24(4)
ERRα Up-Regulates Invadopodia Formation by Targeting HMGCS1 to Promote Endometrial Cancer Invasion and Metastasis.
Tang S, Ma J, Su P, Lei H, Tong Y, Cai L, Xu S, Mao X, Sun P
International journal of molecular sciences 2023 Feb 16;24(4)
International journal of molecular sciences 2023 Feb 16;24(4)
Transplantation of A2 type astrocytes promotes neural repair and remyelination after spinal cord injury.
Chang J, Qian Z, Wang B, Cao J, Zhang S, Jiang F, Kong R, Yu X, Cao X, Yang L, Chen H
Cell communication and signaling : CCS 2023 Feb 16;21(1):37
Cell communication and signaling : CCS 2023 Feb 16;21(1):37
A bat MERS-like coronavirus circulates in pangolins and utilizes human DPP4 and host proteases for cell entry.
Chen J, Yang X, Si H, Gong Q, Que T, Li J, Li Y, Wu C, Zhang W, Chen Y, Luo Y, Zhu Y, Li B, Luo D, Hu B, Lin H, Jiang R, Jiang T, Li Q, Liu M, Xie S, Su J, Zheng X, Li A, Yao Y, Yang Y, Chen P, Wu A, He M, Lin X, Tong Y, Hu Y, Shi ZL, Zhou P
Cell 2023 Feb 16;186(4):850-863.e16
Cell 2023 Feb 16;186(4):850-863.e16
Early activation of Toll-like receptor-3 reduces the pathological progression of Alzheimer's disease in APP/PS1 mouse.
Wang S, Zhu T, Ni W, Zhou C, Zhou H, Lin L, Hu Y, Sun X, Han J, Zhou Y, Jin G, Zu J, Shi H, Yang X, Zhang Z, Hua F
Alzheimer's research & therapy 2023 Feb 16;15(1):33
Alzheimer's research & therapy 2023 Feb 16;15(1):33
The Degree of Hydrolysis and Peptide Profile Affect the Anti-Fatigue Activities of Whey Protein Hydrolysates in Promoting Energy Metabolism in Exercise Mice.
Zhao C, Gong Y, Zheng L, Zhao M
Journal of agricultural and food chemistry 2023 Feb 15;71(6):3010-3021
Journal of agricultural and food chemistry 2023 Feb 15;71(6):3010-3021
Six first-line tyrosine kinase inhibitors reveal novel inhibition potential for the EGFR S768I mutation.
Wang Y, Liu Q, Chu C, Li L, Wang Z, Liu Q, Wu G, Wei X, An L, Ma J
Toxicology and applied pharmacology 2023 Feb 15;461:116385
Toxicology and applied pharmacology 2023 Feb 15;461:116385
Exendin-4 alleviates myocardial ischemia reperfusion injury by enhancing autophagy through promoting nuclear translocation of TFEB.
He W, Tong G, Fan H, Zhen C, Zeng L, Xue L, Chen J, Sun Z, He P
Experimental cell research 2023 Feb 15;423(2):113469
Experimental cell research 2023 Feb 15;423(2):113469
Exosomal circTUBGCP4 promotes vascular endothelial cell tipping and colorectal cancer metastasis by activating Akt signaling pathway.
Chen C, Liu Y, Liu L, Si C, Xu Y, Wu X, Wang C, Sun Z, Kang Q
Journal of experimental & clinical cancer research : CR 2023 Feb 15;42(1):46
Journal of experimental & clinical cancer research : CR 2023 Feb 15;42(1):46
The m(6)A methyltransferase METTL3 affects cell proliferation and migration by regulating YAP expression in Hirschsprung disease.
Huang Z, Luo C, Hou X, Yu D, Su Y, Li X, Luo Y, Liao G, Mu J, Wu K
Pediatric surgery international 2023 Feb 15;39(1):126
Pediatric surgery international 2023 Feb 15;39(1):126
Ferroptosis participated in hippocampal neuroinflammation damage of in offspring rats after maternal sleep deprivation.
Lv J, Xu S, Meng C, Wang Y, Ji L, Li X, Wang X, Li Q
Journal of neuroimmunology 2023 Feb 15;375:578021
Journal of neuroimmunology 2023 Feb 15;375:578021
Selenium alleviates cadmium-induced mitophagy through FUNDC1-mediated mitochondrial quality control pathway in the lungs of sheep.
Lin S, Yang F, Hu M, Chen J, Chen G, Hu A, Li X, Fu D, Xing C, Xiong Z, Wu Y, Cao H
Environmental pollution (Barking, Essex : 1987) 2023 Feb 15;319:120954
Environmental pollution (Barking, Essex : 1987) 2023 Feb 15;319:120954
Design, synthesis and anti-AD effects of dual inhibitor targeting glutaminyl cyclase/GSK-3β.
Xie Y, Chen C, Lin S, Yu X, Ye S, Chen X, Ouyang N, Xiong W, Li C, Xu C, Song G, Wu H
European journal of medicinal chemistry 2023 Feb 15;248:115089
European journal of medicinal chemistry 2023 Feb 15;248:115089
Sulforaphane attenuates microglia-mediated neuronal damage by down-regulating the ROS/autophagy/NLRP3 signal axis in fibrillar Aβ-activated microglia.
Yang Y, Zhang J, Yang C, Dong B, Fu Y, Wang Y, Gong M, Liu T, Qiu P, Xie W, Lü T
Brain research 2023 Feb 15;1801:148206
Brain research 2023 Feb 15;1801:148206
Centriolar satellites expedite mother centriole remodeling to promote ciliogenesis.
Hall EA, Kumar D, Prosser SL, Yeyati PL, Herranz-Pérez V, García-Verdugo JM, Rose L, McKie L, Dodd DO, Tennant PA, Megaw R, Murphy LC, Ferreira MF, Grimes G, Williams L, Quidwai T, Pelletier L, Reiter JF, Mill P
eLife 2023 Feb 15;12
eLife 2023 Feb 15;12
The oncogenic and immunological roles of histidine triad nucleotide-binding protein 1 in human cancers and their experimental validation in the MCF-7 cell line.
Wang X, Zhou M, Jiang L
Annals of translational medicine 2023 Feb 15;11(3):147
Annals of translational medicine 2023 Feb 15;11(3):147
BRD7 inhibits enhancer activity and expression of BIRC2 to suppress tumor growth and metastasis in nasopharyngeal carcinoma.
Li M, Wei Y, Liu Y, Wei J, Zhou X, Duan Y, Chen S, Xue C, Zhan Y, Zheng L, Deng H, Tang F, Fan S, Xiong W, Li G, Tan M, Zhou M
Cell death & disease 2023 Feb 14;14(2):121
Cell death & disease 2023 Feb 14;14(2):121
A genome-wide CRISPR-Cas9 knockout screen identifies FSP1 as the warfarin-resistant vitamin K reductase.
Jin DY, Chen X, Liu Y, Williams CM, Pedersen LC, Stafford DW, Tie JK
Nature communications 2023 Feb 14;14(1):828
Nature communications 2023 Feb 14;14(1):828
Discrepant Activation Pattern of Inflammation and Pyroptosis Induced in Dermal Fibroblasts in Response to Dengue Virus Serotypes 1 and 2 and Nonstructural Protein 1.
Wei KC, Wei WJ, Liao CL, Chang TH
Microbiology spectrum 2023 Feb 14;11(1):e0358622
Microbiology spectrum 2023 Feb 14;11(1):e0358622
Intersection of immune and oncometabolic pathways drives cancer hyperprogression during immunotherapy.
Li G, Choi JE, Kryczek I, Sun Y, Liao P, Li S, Wei S, Grove S, Vatan L, Nelson R, Schaefer G, Allen SG, Sankar K, Fecher LA, Mendiratta-Lala M, Frankel TL, Qin A, Waninger JJ, Tezel A, Alva A, Lao CD, Ramnath N, Cieslik M, Harms PW, Green MD, Chinnaiyan AM, Zou W
Cancer cell 2023 Feb 13;41(2):304-322.e7
Cancer cell 2023 Feb 13;41(2):304-322.e7
Gelatin methacryloyl (GelMA) loaded with concentrated hypoxic pretreated adipose-derived mesenchymal stem cells(ADSCs) conditioned medium promotes wound healing and vascular regeneration in aged skin.
Li S, Sun J, Yang J, Yang Y, Ding H, Yu B, Ma K, Chen M
Biomaterials research 2023 Feb 13;27(1):11
Biomaterials research 2023 Feb 13;27(1):11
Mst1 attenuates myocardial ischemia/reperfusion injury following heterotopic heart transplantation in mice through regulating Keap1/Nrf2 axis.
Fei Q, Liu J, Qiao L, Zhang M, Xia H, Lu D, Wu D, Wang J, Li R, Li J, Yang F, Liu D, Xie B, Hui W, Qian B
Biochemical and biophysical research communications 2023 Feb 12;644:140-148
Biochemical and biophysical research communications 2023 Feb 12;644:140-148
Repositioning Lomitapide to block ZDHHC5-dependant palmitoylation on SSTR5 leads to anti-proliferation effect in preclinical pancreatic cancer models.
Wang Y, Zhang S, He H, Luo H, Xia Y, Jiang Y, Jiang J, Sun L
Cell death discovery 2023 Feb 11;9(1):60
Cell death discovery 2023 Feb 11;9(1):60
A Novel Prenylflavonoid Icariside I Ameliorates Estrogen Deficiency-Induced Osteoporosis via Simultaneous Regulation of Osteoblast and Osteoclast Differentiation.
Chen C, Wu M, Lei H, Cao Z, Wu F, Song Y, Zhang C, Qin M, Zhang C, Du R, Zhou J, Lu Y, Xie D, Zhang L
ACS pharmacology & translational science 2023 Feb 10;6(2):270-280
ACS pharmacology & translational science 2023 Feb 10;6(2):270-280
Qian Yang Yu Yin granule improves hypertensive renal damage: A potential role for TRPC6-CaMKKβ-AMPK-mTOR-mediated autophagy.
Ma S, Xu J, Zheng Y, Li Y, Wang Y, Li H, Fang Z, Li J
Journal of ethnopharmacology 2023 Feb 10;302(Pt A):115878
Journal of ethnopharmacology 2023 Feb 10;302(Pt A):115878
Network pharmacology analysis combined with experimental validation to explore the therapeutic mechanism of Schisandra Chinensis Mixture on diabetic nephropathy.
Ma Y, Deng Y, Li N, Dong A, Li H, Chen S, Zhang S, Zhang M
Journal of ethnopharmacology 2023 Feb 10;302(Pt A):115768
Journal of ethnopharmacology 2023 Feb 10;302(Pt A):115768
KNTC1, regulated by HPV E7, inhibits cervical carcinogenesis partially through Smad2.
Pan W, Wang S, Liu X, Wang M, Han X, Tian X, Lin J, Qiao X, Wang X
Experimental cell research 2023 Feb 1;423(1):113458
Experimental cell research 2023 Feb 1;423(1):113458
Downregulation of CYRI-B promotes migration, invasion and EMT by activating the Rac1-STAT3 pathway in gastric cancer.
Liu G, Xia Y, Wang H, Jin X, Chen S, Chen W, Zhang C, He Y
Experimental cell research 2023 Feb 1;423(1):113453
Experimental cell research 2023 Feb 1;423(1):113453
RPS14 promotes the development and progression of glioma via p53 signaling pathway.
Hu S, Cai J, Fang H, Chen Z, Zhang J, Cai R
Experimental cell research 2023 Feb 1;423(1):113451
Experimental cell research 2023 Feb 1;423(1):113451
Succinate-SUCNR1 induces renal tubular cell apoptosis.
Pu M, Zhang J, Zeng Y, Hong F, Qi W, Yang X, Gao G, Zhou T
American journal of physiology. Cell physiology 2023 Feb 1;324(2):C467-C476
American journal of physiology. Cell physiology 2023 Feb 1;324(2):C467-C476
The collateral activity of RfxCas13d can induce lethality in a RfxCas13d knock-in mouse model.
Li Y, Xu J, Guo X, Li Z, Cao L, Liu S, Guo Y, Wang G, Luo Y, Zhang Z, Wei X, Zhao Y, Liu T, Wang X, Xia H, Kuang M, Guo Q, Li J, Chen L, Wang Y, Li Q, Wang F, Liu Q, You F
Genome biology 2023 Feb 1;24(1):20
Genome biology 2023 Feb 1;24(1):20
Exosomal RBP4 potentiated hepatic lipid accumulation and inflammation in high-fat-diet-fed mice by promoting M1 polarization of Kupffer cells.
Yao JM, Ying HZ, Zhang HH, Qiu FS, Wu JQ, Yu CH
Free radical biology & medicine 2023 Feb 1;195:58-73
Free radical biology & medicine 2023 Feb 1;195:58-73
Aerobic Exercise Ameliorates Myocardial Fibrosis via Affecting Vitamin D Receptor and Transforming Growth Factor-β1 Signaling in Vitamin D-Deficient Mice.
Cui X, Wang K, Zhang J, Cao ZB
Nutrients 2023 Feb 1;15(3)
Nutrients 2023 Feb 1;15(3)
The miR-100-5p Targets SMARCA5 to Regulate the Apoptosis and Intracellular Survival of BCG in Infected THP-1 Cells.
Su L, Zhu T, Liu H, Zhu Y, Peng Y, Tang T, Zhou S, Hu C, Chen H, Guo A, Chen Y
Cells 2023 Feb 1;12(3)
Cells 2023 Feb 1;12(3)
SLAMF7/STAT6 Pathway Inhibits Innate Immune Response in Late-Stage Human Acanthamoeba Keratitis: A Comparative Transcriptome Analysis.
Wei Z, Zhang Y, Chen Q, Xu X, Pan Z, Jin ZB, Liang Q
Microorganisms 2023 Feb 1;11(2)
Microorganisms 2023 Feb 1;11(2)
HSPB8 facilitates prostate cancer progression via activating the JAK/STAT3 signaling pathway.
Zhang K, Yin W, Ma L, Liu Z, Li Q
Biochemistry and cell biology = Biochimie et biologie cellulaire 2023 Feb 1;101(1):1-11
Biochemistry and cell biology = Biochimie et biologie cellulaire 2023 Feb 1;101(1):1-11
Inhibition of Pard3 promotes breast cancer metastasis via the USP28 mediated deubiquitination of Snail1.
Liu Z, Yu Y, Zhou S, Zhang X, Zhou Z
Heliyon 2023 Dec;9(12):e22599
Heliyon 2023 Dec;9(12):e22599
Exosomes derived from human umbilical cord mesenchymal stem cells loaded with RVG-Lamp2b and Netrin-1 promotes Schwann cell invasion and migration.
He J, Du Z, Zhang H, Wang B, Xia J
Tissue & cell 2023 Dec;85:102219
Tissue & cell 2023 Dec;85:102219
Estrogen inhibits the differentiation of fibroblasts induced by high stiffness matrix by enhancing DNMT1 expression.
Zhao Z, Huang G, He Y, Zuo X, Han W, Li H
Tissue & cell 2023 Dec;85:102207
Tissue & cell 2023 Dec;85:102207
AKAP12 inhibits esophageal squamous carcinoma cell proliferation, migration, and cell cycle via the PI3K/AKT signaling pathway.
Li X, Dong H, Zheng Y, Ding S, Li Y, Li H, Huang H, Zhong C, Xie T, Xu Y
Molecular and cellular probes 2023 Dec;72:101939
Molecular and cellular probes 2023 Dec;72:101939
Survivin as a mediator of stiffness-induced cell cycle progression and proliferation of vascular smooth muscle cells.
Biber JC, Sullivan A, Brazzo JA 3rd, Heo Y, Tumenbayar BI, Krajnik A, Poppenberg KE, Tutino VM, Heo SJ, Kolega J, Lee K, Bae Y
APL bioengineering 2023 Dec;7(4):046108
APL bioengineering 2023 Dec;7(4):046108
HDAC3 aberration-incurred GPX4 suppression drives renal ferroptosis and AKI-CKD progression.
Zhang L, Chen F, Dong J, Wang R, Bi G, Xu D, Zhang Y, Deng Y, Lin W, Yang Z, Cao W
Redox biology 2023 Dec;68:102939
Redox biology 2023 Dec;68:102939
High Plant Protein Diet Ameliorated Hepatic Lipid Accumulation Through the Modulation of Gut Microbiota.
Zhu S, Zhao Y, Liu L, Xu Y, Zhu J, Li W, Liu Y, Xia M
Molecular nutrition & food research 2023 Dec;67(24):e2300515
Molecular nutrition & food research 2023 Dec;67(24):e2300515
miR-139-3p/Wnt5A Axis Inhibits Metastasis in Hepatoblastoma.
Wu Z, Chen S, Zuo T, Fu J, Gong J, Liu D, Wang B
Molecular biotechnology 2023 Dec;65(12):2030-2037
Molecular biotechnology 2023 Dec;65(12):2030-2037
CUDC‑101 is a potential target inhibitor for the EGFR‑overexpression bladder cancer cells.
Wang Z, Li L, Chu C, Wei X, Liu Q, Wang R, Zhang G, Wu G, Wang Y, An L, Li X
International journal of oncology 2023 Dec;63(6)
International journal of oncology 2023 Dec;63(6)
JSI-124 inhibits cell proliferation and tumor growth by inducing autophagy and apoptosis in murine malignant mesothelioma.
Zhang C, Sun Q, Zhao J, Jiang N, Hao Y, Luo J, Karim S, Wu L, de Perrot M, Peng C, Zhao X
Molecular carcinogenesis 2023 Dec;62(12):1888-1901
Molecular carcinogenesis 2023 Dec;62(12):1888-1901
Qiqilian ameliorates vascular endothelial dysfunction by inhibiting NLRP3-ASC inflammasome activation in vivo and in vitro.
Luo Y, Tan Z, Ye Y, Ma X, Yue G
Pharmaceutical biology 2023 Dec;61(1):815-824
Pharmaceutical biology 2023 Dec;61(1):815-824
Protective effect of Qingluotongbi formula against Tripterygium wilfordii induced liver injury in mice by improving fatty acid β-oxidation and mitochondrial biosynthesis.
Zhou J, Li M, Yu Z, Li C, Zhou L, Zhou X
Pharmaceutical biology 2023 Dec;61(1):80-88
Pharmaceutical biology 2023 Dec;61(1):80-88
Da-Yuan-Yin decoction polyphenol fraction attenuates acute lung injury induced by lipopolysaccharide.
Guo L, Yang Y, Yuan J, Ren H, Huang X, Li M, Xia L, Jiang X, Chen D, Zhang J
Pharmaceutical biology 2023 Dec;61(1):228-240
Pharmaceutical biology 2023 Dec;61(1):228-240
Mechanisms of dihydromyricetin against hepatocellular carcinoma elucidated by network pharmacology combined with experimental validation.
Zhang S, Shi YN, Gu J, He P, Ai QD, Zhou XD, Wang W, Qin L
Pharmaceutical biology 2023 Dec;61(1):1108-1119
Pharmaceutical biology 2023 Dec;61(1):1108-1119
Schwann Cell-Derived Exosomes Ameliorate Paclitaxel-Induced Peripheral Neuropathy Through the miR-21-Mediated PTEN Signaling Pathway.
You M, Xing H, Yan M, Zhang J, Chen J, Chen Y, Liu X, Zhu J
Molecular neurobiology 2023 Dec;60(12):6840-6851
Molecular neurobiology 2023 Dec;60(12):6840-6851
Cuproptosis-related molecular patterns and gene (ATP7A) in hepatocellular carcinoma and their relationships with tumor immune microenvironment and clinical features.
Li S, Weng J, Xiao C, Lu J, Cao W, Song F, He Z, Zhang P, Zhu Z, Xu J
Cancer reports (Hoboken, N.J.) 2023 Dec;6(12):e1904
Cancer reports (Hoboken, N.J.) 2023 Dec;6(12):e1904
Glioblastoma cellular MAP4K1 facilitates tumor growth and disrupts T effector cell infiltration.
Sun JM, Fan HY, Zhu Y, Pan TT, Wu YP, Zhang DY, Hou XY
Life science alliance 2023 Dec;6(12)
Life science alliance 2023 Dec;6(12)
TUBA1A licenses APC/C-mediated mitotic progression to drive glioblastoma growth by inhibiting PLK3.
Wen J, Wang Q, Zhang W, Wang W
FEBS letters 2023 Dec;597(24):3072-3086
FEBS letters 2023 Dec;597(24):3072-3086
Exosomal microRNA-223 from neutrophil-like cells inhibits osteogenic differentiation of PDLSCs through the cGMP-PKG signaling pathway.
Zhang Z, Wang P, Zheng Y, Wang M, Chou J, Wang Z
Journal of periodontal research 2023 Dec;58(6):1315-1325
Journal of periodontal research 2023 Dec;58(6):1315-1325
DMPP attenuates lipopolysaccharide-induced lung injury by inhibiting glycocalyx degradation through activation of the cholinergic anti-inflammatory pathway.
Qi F, Duan C, Chen T, Li F, Zhang J
Journal of bioenergetics and biomembranes 2023 Dec;55(6):447-456
Journal of bioenergetics and biomembranes 2023 Dec;55(6):447-456
Noncoding mutations cause super-enhancer retargeting resulting in protein synthesis dysregulation during B cell lymphoma progression.
Leeman-Neill RJ, Song D, Bizarro J, Wacheul L, Rothschild G, Singh S, Yang Y, Sarode AY, Gollapalli K, Wu L, Zhang W, Chen Y, Lauring MC, Whisenant DE, Bhavsar S, Lim J, Swerdlow SH, Bhagat G, Zhao Q, Berchowitz LE, Lafontaine DLJ, Wang J, Basu U
Nature genetics 2023 Dec;55(12):2160-2174
Nature genetics 2023 Dec;55(12):2160-2174
Single-cell analysis reveals lysyl oxidase (Lox)(+) fibroblast subset involved in cardiac fibrosis of diabetic mice.
Li H, Zhu X, Cao X, Lu Y, Zhou J, Zhang X
Journal of advanced research 2023 Dec;54:223-237
Journal of advanced research 2023 Dec;54:223-237
Quercetin alleviates lipopolysaccharide‑induced acute lung injury by inhibiting ferroptosis via the Sirt1/Nrf2/Gpx4 pathway.
Deng S, Li J, Li L, Lin S, Yang Y, Liu T, Zhang T, Xie G, Wu D, Xu Y
International journal of molecular medicine 2023 Dec;52(6)
International journal of molecular medicine 2023 Dec;52(6)
An adverse outcome pathway-based approach to assess the neurotoxicity by combined exposure to current-use pesticides.
Hirano T, Ikenaka Y, Nomiyama K, Honda M, Suzuki N, Hoshi N, Tabuchi Y
Toxicology 2023 Dec;500:153687
Toxicology 2023 Dec;500:153687
Bisphenol A induced neuronal apoptosis and enhanced autophagy in vitro through Nrf2/HO-1 and Akt/mTOR pathways.
Shen Y, Li X, Wang H, Wang Y, Tao L, Wang P, Zhang H
Toxicology 2023 Dec;500:153678
Toxicology 2023 Dec;500:153678
Licochalcone A induces cell cycle arrest and apoptosis via suppressing MAPK signaling pathway and the expression of FBXO5 in lung squamous cell cancer.
Fan X, Guan G, Wang J, Jin M, Wang L, Duan X
Oncology reports 2023 Dec;50(6)
Oncology reports 2023 Dec;50(6)
Metformin Improves Comorbid Depressive Symptoms in Mice with Allergic Rhinitis by Reducing Olfactory Bulb Damage.
Lv H, Gao Z, Wang Y, Chen S, Liu P, Xie Y, Guan M, Cong J, Xu Y
Neurochemical research 2023 Dec;48(12):3639-3651
Neurochemical research 2023 Dec;48(12):3639-3651
Transcriptome sequencing identifies prognostic genes involved in gastric adenocarcinoma.
Li M, Bai M, Wu Y, Yang S, Zheng L, Sun L, Yu C, Huang Y
Molecular and cellular biochemistry 2023 Dec;478(12):2891-2906
Molecular and cellular biochemistry 2023 Dec;478(12):2891-2906
Triggering pyroptosis enhances the antitumor efficacy of PARP inhibitors in prostate cancer.
Tian A, Wu T, Zhang Y, Chen J, Sha J, Xia W
Cellular oncology (Dordrecht, Netherlands) 2023 Dec;46(6):1855-1870
Cellular oncology (Dordrecht, Netherlands) 2023 Dec;46(6):1855-1870
CircGLIS3 inhibits thyroid cancer invasion and metastasis through miR-146b-3p/AIF1L axis.
Cao S, Yin Y, Hu H, Hong S, He W, Lv W, Liu R, Li Y, Yu S, Xiao H
Cellular oncology (Dordrecht, Netherlands) 2023 Dec;46(6):1777-1789
Cellular oncology (Dordrecht, Netherlands) 2023 Dec;46(6):1777-1789
CircTLK1 alleviates oxygen-glucose deprivation/reperfusion induced apoptosis in HK-2 cells through miR-136-5p/Bcl2 signal axis.
Kuang L, Lu A, Yao S
Renal failure 2023 Dec;45(1):2236219
Renal failure 2023 Dec;45(1):2236219
PFKFB3 downregulation aggravates Angiotensin II-induced podocyte detachment.
Huang X, Chen Z, Luo Z, Hao Y, Feng J, Zhu Z, Yang X, Zhang Z, Hu J, Liang W, Ding G
Renal failure 2023 Dec;45(1):2230318
Renal failure 2023 Dec;45(1):2230318
Salt-induced phosphoproteomic changes in the subfornical organ in rats with chronic kidney disease.
Wang X, Wang H, Li J, Li L, Wang Y, Li A
Renal failure 2023 Dec;45(1):2171886
Renal failure 2023 Dec;45(1):2171886
HBx-induced PLA(2)R overexpression mediates podocyte pyroptosis through the ROS-NLRP3 signaling pathway.
Feng M, Yu Y, Chen Y, Yang X, Li B, Jiang W
Renal failure 2023 Dec;45(1):2170808
Renal failure 2023 Dec;45(1):2170808
Blockage of EGFR/AKT and mevalonate pathways synergize the antitumor effect of temozolomide by reprogramming energy metabolism in glioblastoma.
Cui X, Zhao J, Li G, Yang C, Yang S, Zhan Q, Zhou J, Wang Y, Xiao M, Hong B, Yi K, Tong F, Tan Y, Wang H, Wang Q, Jiang T, Fang C, Kang C
Cancer communications (London, England) 2023 Dec;43(12):1326-1353
Cancer communications (London, England) 2023 Dec;43(12):1326-1353
Dual network analysis of transcriptome data for discovery of new therapeutic targets in non-small cell lung cancer.
Bai Y, Zhou L, Zhang C, Guo M, Xia L, Tang Z, Liu Y, Deng S
Oncogene 2023 Dec;42(49):3605-3618
Oncogene 2023 Dec;42(49):3605-3618
ATR-dependent ubiquitin-specific protease 20 phosphorylation confers oxaliplatin and ferroptosis resistance.
Tang J, Long G, Xiao D, Liu S, Xiao L, Zhou L, Tao Y
MedComm 2023 Dec;4(6):e463
MedComm 2023 Dec;4(6):e463
GALNT2, an O-glycosylating enzyme, is a critical regulator of radioresistance of non-small cell lung cancer: evidence from an integrated multi-omics analysis.
Dong X, Leng Y, Tian T, Hu Q, Chen S, Liu Y, Shen L
Cell biology and toxicology 2023 Dec;39(6):3159-3174
Cell biology and toxicology 2023 Dec;39(6):3159-3174
Hyperhomocysteinemia lowers serum testosterone concentration via impairing testosterone production in Leydig cells.
Su Z, Liu Z, Lei W, Xia K, Xiao A, Hu Z, Zhou M, Zhu F, Tian J, Yang M, Wang D, Xiang AP, Nie J
Cell biology and toxicology 2023 Dec;39(6):3077-3100
Cell biology and toxicology 2023 Dec;39(6):3077-3100
Mutation of aspartic acid 262 on estrogen receptor abrogates estradiol signaling pathway.
Xu X, Yu H, Zhu S, Li P, Li X, Gao Y, Xiang Y, Zhao G, Simoncini T, Lin H
Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 2023 Dec;39(1):2250881
Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 2023 Dec;39(1):2250881
Classical swine fever virus NS5A protein antagonizes innate immune response by inhibiting the NF-κB signaling.
Sun J, Li J, Li L, Yu H, Ma P, Wang Y, Zhu J, Feng Z, Tu C
Virologica Sinica 2023 Dec;38(6):900-910
Virologica Sinica 2023 Dec;38(6):900-910
Higher matrix stiffness promotes VSMC senescence by affecting mitochondria-ER contact sites and mitochondria/ER dysfunction.
He H, Zeng B, Wu X, Hou J, Wang Y, Wang Y, Lin Y, Wu P, Zheng C, Yin H, Wang N
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Dec;37(12):e23318
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Dec;37(12):e23318
Downregulation of ALKBH5 rejuvenates aged human mesenchymal stem cells and enhances their therapeutic efficacy in myocardial infarction.
Gao X, Liang X, Liu B, Hong Y, He H, Shen Y, Chen J, Huang X, Hu B, Li W, Li X, Zhang Y
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Dec;37(12):e23294
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Dec;37(12):e23294
The SARS-CoV-2 nucleocapsid protein suppresses innate immunity by remodeling stress granules to atypical foci.
He S, Gou H, Zhou Y, Wu C, Ren X, Wu X, Guan G, Jin B, Huang J, Jin Z, Zhao T
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Dec;37(12):e23269
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Dec;37(12):e23269
Neurovascular dysfunction associated with erectile dysfunction persists after long-term recovery from simulations of weightlessness and deep space irradiation.
Andrade MR, Azeez TA, Montgomery MM, Caldwell JT, Park H, Kwok AT, Borg AM, Narayanan SA, Willey JS, Delp MD, La Favor JD
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Dec;37(12):e23246
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Dec;37(12):e23246
β-arrestin1 is an E3 ubiquitin ligase adaptor for substrate linear polyubiquitination.
McElrath CJ, Benzow S, Zhuo Y, Marchese A
The Journal of biological chemistry 2023 Dec;299(12):105474
The Journal of biological chemistry 2023 Dec;299(12):105474
Multiple N-linked glycosylation sites critically modulate the synaptic abundance of neuroligin isoforms.
Benner O, Cast TP, Minamide LS, Lenninger Z, Bamburg JR, Chanda S
The Journal of biological chemistry 2023 Dec;299(12):105361
The Journal of biological chemistry 2023 Dec;299(12):105361
Tumor Necrosis Factor Alpha Preconditioned Umbilical Cord Mesenchymal Stem Cell-Derived Extracellular Vesicles Enhance the Inhibition of Necroptosis of Acinar cells in Severe Acute Pancreatitis.
Xie W, Luo T, Ma Z, Xue S, Jia X, Yang T, Song Z
Tissue engineering. Part A 2023 Dec;29(23-24):607-619
Tissue engineering. Part A 2023 Dec;29(23-24):607-619
CDC20 promotes radioresistance of prostate cancer by activating Twist1 expression.
Yang C, Ge Y, Zang Y, Xu M, Jin L, Wang Y, Xu X, Xue B, Wang Z, Wang L
Apoptosis : an international journal on programmed cell death 2023 Dec;28(11-12):1584-1595
Apoptosis : an international journal on programmed cell death 2023 Dec;28(11-12):1584-1595
An immunogenic cell death-related signature predicts prognosis and immunotherapy response in stomach adenocarcinoma.
Liu Z, Sun L, Peng X, Liu S, Zhu Z, Huang C
Apoptosis : an international journal on programmed cell death 2023 Dec;28(11-12):1564-1583
Apoptosis : an international journal on programmed cell death 2023 Dec;28(11-12):1564-1583
Bioinformatic analysis of the expression profile and identification of RhoGDI2 as a biomarker in imatinib-resistant K562 cells.
Yang Y, Zhong F, Jiang J, Li M, Yao F, Liu J, Cheng Y, Xu S, Chen S, Zhang H, Xu Y, Huang B
Hematology (Amsterdam, Netherlands) 2023 Dec;28(1):2244856
Hematology (Amsterdam, Netherlands) 2023 Dec;28(1):2244856
Polydatin alleviates bleomycin-induced pulmonary fibrosis and alters the gut microbiota in a mouse model.
Yang J, Shi X, Gao R, Fan L, Chen R, Cao Y, Xu T, Yang J
Journal of cellular and molecular medicine 2023 Dec;27(23):3717-3728
Journal of cellular and molecular medicine 2023 Dec;27(23):3717-3728
Xanthohumol attenuates renal ischemia/reperfusion injury by inhibiting ferroptosis.
Tang Z, Feng Y, Nie W, Li C
Experimental and therapeutic medicine 2023 Dec;26(6):571
Experimental and therapeutic medicine 2023 Dec;26(6):571
SPINT2 is involved in the proliferation, migration and phenotypic switching of aortic smooth muscle cells: Implications for the pathogenesis of thoracic aortic dissection.
Li J, Yu C, Yu K, Chen Z, Xing D, Zha B, Xie W, Ouyang H
Experimental and therapeutic medicine 2023 Dec;26(6):546
Experimental and therapeutic medicine 2023 Dec;26(6):546
EIF2α/ATF4 pathway enhances proliferation of mesangial cell via cyclin D1 during endoplasmic reticulum stress in IgA nephropathy.
Lan Z, Zhao L, Peng L, Wan L, Liu D, Tang C, Chen G, Liu Y, Liu H
Clinical immunology (Orlando, Fla.) 2023 Dec;257:109840
Clinical immunology (Orlando, Fla.) 2023 Dec;257:109840
SIRT6 Knockdown in Buffalo Fetal Fibroblasts Exacerbates Premature Senescence Caused by DNA and Telomere Damage.
Liang J, Cui J, Cheng J, Pan Y, Zhang R, Yang S, Zou L
Cellular reprogramming 2023 Dec;25(6):277-287
Cellular reprogramming 2023 Dec;25(6):277-287
Ferritinophagy-mediated apoptosis and paraptosis induction involved MAPK and PI3K/AKT pathway in mechanism of an iron chelator.
Wang R, Li J, Fu Y, Li Y, Qi Y, Li C, Gao F, Li C
Biochemical pharmacology 2023 Dec;218:115874
Biochemical pharmacology 2023 Dec;218:115874
USP10 promotes the progression of triple-negative breast cancer by enhancing the stability of TCF4 protein.
Yang JR, Lu YB, Su HX, Xiao Y, Pan Q, Su F, Zhang XB, Zhu KL, Guan QL, Ling XL
Biochemical pharmacology 2023 Dec;218:115864
Biochemical pharmacology 2023 Dec;218:115864
SINE-VNTR-Alu retrotransposon insertion as a novel mutational event underlying Glanzmann thrombasthenia.
Zhang J, Tang J, Li G, Li N, Wang J, Yao R, Yu T
Journal of thrombosis and haemostasis : JTH 2023 Dec;21(12):3597-3607
Journal of thrombosis and haemostasis : JTH 2023 Dec;21(12):3597-3607
Monopolar spindle 1 contributes to tamoxifen resistance in breast cancer through phosphorylation of estrogen receptor α.
Zhang X, Huang L, Sun J, Liu J, Zong Y, Wan L, Yang X, Yan X, Zhang Y, Zhao R, Liu J, Zhong H, Wei C, Yang X, Tai Y, Han Y, Wang Y
Breast cancer research and treatment 2023 Dec;202(3):595-606
Breast cancer research and treatment 2023 Dec;202(3):595-606
Vitamin D/Vitamin D receptor mitigates cisplatin-induced acute kidney injury by down-regulating C5aR.
Wen Z, Sun C, Lou Y, Kong J
Journal of immunotoxicology 2023 Dec;20(1):2248267
Journal of immunotoxicology 2023 Dec;20(1):2248267
Dexmedetomidine attenuates the neuroinflammation and cognitive dysfunction in aged mice by targeting the SNHG14/miR‑340/NF‑κB axis.
He G, Ni H, Wang K, Gao H, Li Y, Gu J, Ni X, Wang Z, Bao Y
Biomedical reports 2023 Dec;19(6):100
Biomedical reports 2023 Dec;19(6):100
NSUN2-mediated m5C modification of HBV RNA positively regulates HBV replication.
Feng J, Xu T, He M, Li J, Yao P, Ma C, Yang S, Xu Z, Yan K, Chen X, Wang H, Liu J, Zeng C, Xia Y, Yan H, Zhou L, Chen Y
PLoS pathogens 2023 Dec;19(12):e1011808
PLoS pathogens 2023 Dec;19(12):e1011808
Overexpression of LOX-1 in hepatocytes protects vascular smooth muscle cells from phenotype transformation and wire injury induced carotid neoatherosclerosis through ALOX15.
Zhang Q, Du G, Tong L, Guo X, Wei Y
Biochimica et biophysica acta. Molecular basis of disease 2023 Dec;1869(8):166805
Biochimica et biophysica acta. Molecular basis of disease 2023 Dec;1869(8):166805
Glimepiride, a novel soluble epoxide hydrolase inhibitor, protects against heart failure via increasing epoxyeicosatrienoic acids.
Zhao C, Jiang X, Peng L, Zhang Y, Li H, Zhang Q, Wang Y, Yang F, Wu J, Wen Z, He Z, Shen J, Chen C, Wang DW
Journal of molecular and cellular cardiology 2023 Dec;185:13-25
Journal of molecular and cellular cardiology 2023 Dec;185:13-25
Dietary pectin attenuates Salmonella typhimurium-induced colitis by modulating the TLR2-NF-κB pathway and intestinal microbiota in mice.
Li J, Bai J, Song Z, Ji Y, Chen Z, Yang Y, Wu Z
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2023 Dec;182:114100
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2023 Dec;182:114100
Sanguinarine induces apoptosis in osteosarcoma by attenuating the binding of STAT3 to the single-stranded DNA-binding protein 1 (SSBP1) promoter region.
Wang KD, Zhu ML, Qin CJ, Dong RF, Xiao CM, Lin Q, Wei RY, He XY, Zang X, Kong LY, Xia YZ
British journal of pharmacology 2023 Dec;180(24):3175-3193
British journal of pharmacology 2023 Dec;180(24):3175-3193
5-HT4 Receptor is Protective for MPTP-induced Parkinson's Disease Mice Via Altering Gastrointestinal Motility or Gut Microbiota.
Cui C, Shi Y, Hong H, Zhou Y, Qiao C, Zhao L, Jia X, Zhao W, Shen Y
Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology 2023 Dec;18(4):610-627
Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology 2023 Dec;18(4):610-627
TRAF5 regulates intestinal mucosal Th1/Th17 cell immune responses via Runx1 in colitis mice.
Li M, Gan C, Zhang R, Wang J, Wang Y, Zhu W, Liu L, Shang J, Zhao Q
Immunology 2023 Dec;170(4):495-509
Immunology 2023 Dec;170(4):495-509
The synthetic oleanane triterpenoid CDDO-2P-Im binds GRP78/BiP to induce unfolded protein response-mediated apoptosis in myeloma.
Luo G, Aldridge K, Chen T, Aslot V, Kim BG, Han EH, Singh N, Li S, Xiao TS, Sporn MB, Letterio JJ
Molecular oncology 2023 Dec;17(12):2526-2545
Molecular oncology 2023 Dec;17(12):2526-2545
Knockdown of LMNA inhibits Akt/β-catenin-mediated cell invasion and migration in clear cell renal cell carcinoma cells.
Xin H, Tang Y, Jin YH, Li HL, Tian Y, Yu C, Zhao ZJ, Wu MS, Pan YF
Cell adhesion & migration 2023 Dec;17(1):1-14
Cell adhesion & migration 2023 Dec;17(1):1-14
Salvianolic acid A alleviates heart failure with preserved ejection fraction via regulating TLR/Myd88/TRAF/NF-κB and p38MAPK/CREB signaling pathways.
Dawuti A, Sun S, Wang R, Gong D, Liu R, Kong D, Yuan T, Zhou J, Lu Y, Wang S, Du G, Fang L
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Dec;168:115837
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Dec;168:115837
Liensinine alleviates LPS-induced acute lung injury by blocking autophagic flux via PI3K/AKT/mTOR signaling pathway.
Wang C, Zou K, Diao Y, Zhou C, Zhou J, Yang Y, Zeng Z
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Dec;168:115813
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Dec;168:115813
Traditional Medicine Pien Tze Huang Suppresses Colorectal Tumorigenesis Through Restoring Gut Microbiota and Metabolites.
Gou H, Su H, Liu D, Wong CC, Shang H, Fang Y, Zeng X, Chen H, Li Y, Huang Z, Fan M, Wei C, Wang X, Zhang X, Li X, Yu J
Gastroenterology 2023 Dec;165(6):1404-1419
Gastroenterology 2023 Dec;165(6):1404-1419
METTL3-mediated m6A modification of circRNF220 modulates miR-330-5p/survivin axis to promote osteosarcoma progression.
Liu F, Li W, Jin Z, Ye J
Journal of cancer research and clinical oncology 2023 Dec;149(19):17347-17360
Journal of cancer research and clinical oncology 2023 Dec;149(19):17347-17360
Identification of glycogene-based prognostic signature and validation of B3GNT7 as a potential biomarker and therapeutic target in breast cancer.
Wang X, Wang Y, Chen X, He Y, Zhou X, Jiao S, Zhu Z, Wu C, Bao J
Journal of cancer research and clinical oncology 2023 Dec;149(19):16957-16969
Journal of cancer research and clinical oncology 2023 Dec;149(19):16957-16969
B7-H3 and CD47 co-expression in gastric cancer is a predictor of poor prognosis and potential targets for future dual-targeting immunotherapy.
Chen S, Zhan S, Ding S, Zhang Q, Xuan H, Zhang X, Cao L
Journal of cancer research and clinical oncology 2023 Dec;149(18):16609-16621
Journal of cancer research and clinical oncology 2023 Dec;149(18):16609-16621
Discovery of selective and potent USP22 inhibitors via structure-based virtual screening and bioassays exerting anti-tumor activity.
Zhang Y, Song J, Zhou Y, Jia H, Zhou T, Sun Y, Gao Q, Zhao Y, Pan Y, Sun Z, Chu P
Bioorganic chemistry 2023 Dec;141:106842
Bioorganic chemistry 2023 Dec;141:106842
Circadian Clock REV-ERBs Agonist SR9009 Induces Synergistic Antitumor Activity in Multiple Myeloma by Suppressing Glucose-Regulated Protein 78-Dependent Autophagy and Lipogenesis.
Wang R, Liu SL, Guo QQ, Shi XH, Ma MM
World journal of oncology 2023 Dec;14(6):464-475
World journal of oncology 2023 Dec;14(6):464-475
Stimulator of interferon genes promotes diabetic sarcopenia by targeting peroxisome proliferator activated receptors γ degradation and inhibiting fatty acid oxidation.
Yan SB, Liang H, Zhan P, Zheng H, Zhao QX, Zheng ZJ, Lu HX, Shang GK, Ji XP
Journal of cachexia, sarcopenia and muscle 2023 Dec;14(6):2623-2641
Journal of cachexia, sarcopenia and muscle 2023 Dec;14(6):2623-2641
CiRS-7 Enhances the Liquid-liquid Phase Separation of miRISC and Promotes DNA Damage Repair.
Wang YL, Feng LL, Shi J, Chen WY, Bie SY, Bai SM, Zeng GD, Wang RZ, Zheng J, Wan XB, Fan XJ
Nucleus (Austin, Tex.) 2023 Dec;14(1):2293599
Nucleus (Austin, Tex.) 2023 Dec;14(1):2293599
The pseudokinase MLKL contributes to host defense against Streptococcus pluranimalium infection by mediating NLRP3 inflammasome activation and extracellular trap formation.
Lei YX, Liu Y, Xing LH, Wu YJ, Wang XY, Meng FH, Lou YN, Ma ZG, Yuan L, Yu SX
Virulence 2023 Dec;14(1):2258057
Virulence 2023 Dec;14(1):2258057
Cyclin-dependent kinase 5 negatively regulates antiviral immune response by disrupting myeloid differentiation primary response protein 88 self-association.
Ren JP, Cong HL, Gao LJ, Jiang DF, Li XT, Wang Y, Wang JQ, Tang TS
Virulence 2023 Dec;14(1):2223394
Virulence 2023 Dec;14(1):2223394
Effects of different types of neonatal pain on somatosensory and cognitive development in male juvenile rats.
Ling R, Wang Y, Zheng W, Min C, Chen M, Xia D, Li X
Brain and behavior 2023 Dec;13(12):e3309
Brain and behavior 2023 Dec;13(12):e3309
L-F001, a multifunctional fasudil-lipoic acid dimer, antagonizes hypoxic-ischemic brain damage by inhibiting the TLR4/MyD88 signaling pathway.
Zhou R, Wu L, Jin N, Sha S, Ouyang Y
Brain and behavior 2023 Dec;13(12):e3280
Brain and behavior 2023 Dec;13(12):e3280
Zinc regulates a specific subpopulation of VEGFA + microglia to improve the hypoxic microenvironment for functional recovery after spinal cord injury.
Deng H, Liu Y, Shi Z, Yang J, Liu C, Mei X
International immunopharmacology 2023 Dec;125(Pt A):111092
International immunopharmacology 2023 Dec;125(Pt A):111092
Decreased SIRT1 mRNA expression in peripheral blood mononuclear cells from patients with neuromyelitis optica spectrum disorders.
Zhang L, Xue Y, Yuan C, Du X, Wang X, Guo L, Li B
Acta neurologica Belgica 2023 Dec;123(6):2287-2294
Acta neurologica Belgica 2023 Dec;123(6):2287-2294
Ginsenoside Rb1 protects hippocampal neurons in depressed rats based on mitophagy-regulated astrocytic pyroptosis.
Li Y, Li J, Yang L, Ren F, Dong K, Zhao Z, Duan W, Wei W, Guo R
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Dec;121:155083
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Dec;121:155083
NSUN2-mediated M(5)c methylation of IRF3 mRNA negatively regulates type I interferon responses during various viral infections.
Wang H, Feng J, Zeng C, Liu J, Fu Z, Wang D, Wang Y, Zhang L, Li J, Jiang A, He M, Cao Y, Yan K, Tang H, Guo D, Xu K, Zhou X, Zhou L, Lan K, Zhou Y, Chen Y
Emerging microbes & infections 2023 Dec;12(1):2178238
Emerging microbes & infections 2023 Dec;12(1):2178238
DUSP2 affects bladder cancer prognosis by down-regulating MEK/ERK and P38 MAPK signaling pathways through PTPN7.
Zou F, Rao T, Chen W, Song T, Li T, Hu W, Li L, Yu W, Cheng F
Cellular signalling 2023 Dec;112:110893
Cellular signalling 2023 Dec;112:110893
ZNF746 promotes M2 macrophage polarisation and favours tumour progression in breast cancer via the Jagged1/Notch pathway.
Liu L, Zhao WY, Zheng XY
Cellular signalling 2023 Dec;112:110892
Cellular signalling 2023 Dec;112:110892
Umbelliferone attenuates cisplatin-induced acute kidney injury by inhibiting oxidative stress and inflammation via NRF2.
Yang Z, Ning R, Liu Q, Zang R, Liu S, Sun S
Physiological reports 2023 Dec;11(23):e15879
Physiological reports 2023 Dec;11(23):e15879
STAG2 Regulates Homologous Recombination Repair and Sensitivity to ATM Inhibition.
Zhou J, Nie RC, He ZP, Cai XX, Chen JW, Lin WP, Yin YX, Xiang ZC, Zhu TC, Xie JJ, Zhang YC, Wang X, Lin P, Xie D, D'Andrea AD, Cai MY
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Dec;10(36):e2302494
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Dec;10(36):e2302494
Targeting CBX3 with a Dual BET/PLK1 Inhibitor Enhances the Antitumor Efficacy of CDK4/6 Inhibitors in Prostate Cancer.
Liang H, Yang C, Zeng R, Song Y, Wang J, Xiong W, Yan B, Jin X
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Dec;10(36):e2302368
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Dec;10(36):e2302368
SUCLG2 Regulates Mitochondrial Dysfunction through Succinylation in Lung Adenocarcinoma.
Hu Q, Xu J, Wang L, Yuan Y, Luo R, Gan M, Wang K, Zhao T, Wang Y, Han T, Wang JB
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Dec;10(35):e2303535
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Dec;10(35):e2303535
NS2B-D55E and NS2B-E65D Variations are Responsible for Differences in NS2B-NS3 Protease Activities Between Japanese Encephalitis Virus Genotype I and III in Fluorogenic Peptide Model.
Wahaab A, Zhang Y, Rasgon JL, Kang L, Hameed M, Li C, Anwar MN, Zhang Y, Shoaib A, Liu K, Lee B, Wei J, Qiu Y, Ma Z
bioRxiv : the preprint server for biology 2023 Dec 9;
bioRxiv : the preprint server for biology 2023 Dec 9;
Heat shock protein HSPA13 promotes hepatocellular carcinoma progression by stabilizing TANK.
Cen X, Lu Y, Lu J, Luo C, Zhan P, Cheng Y, Yang F, Xie C, Yin Z, Wang F
Cell death discovery 2023 Dec 8;9(1):443
Cell death discovery 2023 Dec 8;9(1):443
Nutrient deprivation alters the rate of COPII subunit recruitment at ER subdomains to tune secretory protein transport.
Kasberg W, Luong P, Swift KA, Audhya A
Nature communications 2023 Dec 8;14(1):8140
Nature communications 2023 Dec 8;14(1):8140
Structural and biochemical insights into the interaction mechanism underlying HORMAD1 and its partner proteins.
Wang H, Xie R, Niu F, Yang Q, An L, Wu C, Liu X, Yang X
Structure (London, England : 1993) 2023 Dec 7;31(12):1578-1588.e3
Structure (London, England : 1993) 2023 Dec 7;31(12):1578-1588.e3
VEGFA mRNA-LNP promotes biliary epithelial cell-to-hepatocyte conversion in acute and chronic liver diseases and reverses steatosis and fibrosis.
Rizvi F, Lee YR, Diaz-Aragon R, Bawa PS, So J, Florentino RM, Wu S, Sarjoo A, Truong E, Smith AR, Wang F, Everton E, Ostrowska A, Jung K, Tam Y, Muramatsu H, Pardi N, Weissman D, Soto-Gutierrez A, Shin D, Gouon-Evans V
Cell stem cell 2023 Dec 7;30(12):1640-1657.e8
Cell stem cell 2023 Dec 7;30(12):1640-1657.e8
The hypothalamic steroidogenic pathway mediates susceptibility to inflammation-evoked depression in female mice.
Xu FR, Wei ZH, Xu XX, Zhang XG, Wei CJ, Qi XM, Li YH, Gao XL, Wu Y
Journal of neuroinflammation 2023 Dec 7;20(1):293
Journal of neuroinflammation 2023 Dec 7;20(1):293
IFITM1 and IFITM3 Proteins Inhibit the Infectivity of Progeny HIV-1 without Disrupting Envelope Glycoprotein Clusters.
Verma S, Chen YC, Marin M, Gillespie SE, Melikyan GB
Viruses 2023 Dec 7;15(12)
Viruses 2023 Dec 7;15(12)
Aldehyde dehydrogenase 2-mediated aldehyde metabolism promotes tumor immune evasion by regulating the NOD/VISTA axis.
Chen Y, Sun J, Liu J, Wei Y, Wang X, Fang H, Du H, Huang J, Li Q, Ren G, Wang X, Li H
Journal for immunotherapy of cancer 2023 Dec 7;11(12)
Journal for immunotherapy of cancer 2023 Dec 7;11(12)
Spinal-Specific Super Enhancer in Neuropathic Pain.
Tao Y, Wang QH, Li XT, Liu Y, Sun RH, Xu HJ, Zhang M, Li SY, Yang L, Wang HJ, Hao LY, Cao JL, Pan Z
The Journal of neuroscience : the official journal of the Society for Neuroscience 2023 Dec 6;43(49):8547-8561
The Journal of neuroscience : the official journal of the Society for Neuroscience 2023 Dec 6;43(49):8547-8561
Androgen signaling stabilizes genomes to counteract senescence by promoting XRCC4 transcription.
Chen Y, Zhen Z, Chen L, Wang H, Wang X, Sun X, Song Z, Wang H, Lin Y, Zhang W, Wu G, Jiang Y, Mao Z
EMBO reports 2023 Dec 6;24(12):e56984
EMBO reports 2023 Dec 6;24(12):e56984
GDF15 is a major determinant of ketogenic diet-induced weight loss.
Lu JF, Zhu MQ, Xia B, Zhang NN, Liu XP, Liu H, Zhang RX, Xiao JY, Yang H, Zhang YQ, Li XM, Wu JW
Cell metabolism 2023 Dec 5;35(12):2165-2182.e7
Cell metabolism 2023 Dec 5;35(12):2165-2182.e7
A missense mutant of ocrl1 promotes apoptosis of tubular epithelial cells and disrupts endocytosis and the cell cycle of podocytes in Dent-2 Disease.
Huang L, Zhang Y, Fu H, Gu W, Mao J
Cell communication and signaling : CCS 2023 Dec 5;21(1):256
Cell communication and signaling : CCS 2023 Dec 5;21(1):256
RNA-binding motif protein 10 inactivates c-Myc by partnering with ribosomal proteins uL18 and uL5.
Lee H, Jung JH, Ko HM, Park H, Segall AM, Sheffmaker RL, Wang J, Frey WD, Pham N, Wang Y, Zhang Y, Jackson JG, Zeng SX, Lu H
Proceedings of the National Academy of Sciences of the United States of America 2023 Dec 5;120(49):e2308292120
Proceedings of the National Academy of Sciences of the United States of America 2023 Dec 5;120(49):e2308292120
Protective Effect of Ginsenoside CK against Autoimmune Hepatitis Induced by Concanavalin A.
Zhang J, Liu Y, An C, Liu C, Ma S, Zhang Q, Ding H, Shao J, Xue W
Foods (Basel, Switzerland) 2023 Dec 5;12(24)
Foods (Basel, Switzerland) 2023 Dec 5;12(24)
Satellite glial GPR37L1 regulates maresin and potassium channel signaling for pain control.
Bang S, Jiang C, Xu J, Chandra S, McGinnis A, Luo X, He Q, Li Y, Wang Z, Ao X, Parisien M, Fernandes de Araujo LO, Esfahan SJ, Zhang Q, Tonello R, Berta T, Diatchenko L, Ji RR
bioRxiv : the preprint server for biology 2023 Dec 5;
bioRxiv : the preprint server for biology 2023 Dec 5;
Interplay between stochastic enzyme activity and microtubule stability drives detyrosination enrichment on microtubule subsets.
Tang Q, Sensale S, Bond C, Xing J, Qiao A, Hugelier S, Arab A, Arya G, Lakadamyali M
Current biology : CB 2023 Dec 4;33(23):5169-5184.e8
Current biology : CB 2023 Dec 4;33(23):5169-5184.e8
hsa_circ_0007919 induces LIG1 transcription by binding to FOXA1/TET1 to enhance the DNA damage response and promote gemcitabine resistance in pancreatic ductal adenocarcinoma.
Xu L, Ma X, Zhang X, Zhang C, Zhang Y, Gong S, Wu N, Zhang P, Feng X, Guo J, Zhao M, Ren Z, Zhang P
Molecular cancer 2023 Dec 4;22(1):195
Molecular cancer 2023 Dec 4;22(1):195
A ketogenic diet reduces age-induced chronic neuroinflammation in mice Running title: ketogenic diet and brain inflammaging.
Nomura M, Murad NF, Madhavan SS, Eap B, Garcia TY, Aguirre CG, Verdin E, Ellerby L, Furman D, Newman JC
bioRxiv : the preprint server for biology 2023 Dec 4;
bioRxiv : the preprint server for biology 2023 Dec 4;
Establishment of a Fah-LSL mouse model to study BEC-to-hepatocyte conversion.
Wang X, Pu W, Zhu H, Zhang M, Zhou B
Biophysics reports 2023 Dec 31;9(6):309-324
Biophysics reports 2023 Dec 31;9(6):309-324
A20 ameliorates Aspergillus fumigatus keratitis by promoting autophagy and inhibiting NF-κB signaling.
Han F, Wang L, Shen L, Liu W, Li Y, Ma H, Wu X
International journal of biological macromolecules 2023 Dec 31;253(Pt 8):127640
International journal of biological macromolecules 2023 Dec 31;253(Pt 8):127640
Exopolysaccharide from Weissella confusa J4-1 inhibits colorectal cancer via induction of cell cycle arrest.
Liu L, Du Y, Du Y, Yan W, Li Y, Cui K, Li Z, Yu P, Zhang W, Feng J, Ma W, Zhao H
International journal of biological macromolecules 2023 Dec 31;253(Pt 8):127625
International journal of biological macromolecules 2023 Dec 31;253(Pt 8):127625
DnaJs are enriched in tau regulators.
Esquivel AR, Hill SE, Blair LJ
International journal of biological macromolecules 2023 Dec 31;253(Pt 7):127486
International journal of biological macromolecules 2023 Dec 31;253(Pt 7):127486
LncHLEF promotes hepatic lipid synthesis through miR-2188-3p/GATA6 axis and encoding peptides and enhances intramuscular fat deposition via exosome.
Guo Y, Tian W, Wang D, Yang L, Wang Z, Wu X, Zhi Y, Zhang K, Wang Y, Li Z, Jiang R, Sun G, Li G, Tian Y, Wang H, Kang X, Liu X, Li H
International journal of biological macromolecules 2023 Dec 31;253(Pt 5):127061
International journal of biological macromolecules 2023 Dec 31;253(Pt 5):127061
Cataract-causing mutations S78F and S78P of γD-crystallin decrease protein conformational stability and drive aggregation.
Lin N, Zhang Y, Song X, Xu J, Luo C, Tian Q, Yao K, Wu W, Chen X, Hu L
International journal of biological macromolecules 2023 Dec 31;253(Pt 4):126910
International journal of biological macromolecules 2023 Dec 31;253(Pt 4):126910
miRNA-660-3p inhibits malignancy in glioblastoma via negative regulation of APOC1-TGFβ2 signaling pathway.
Yang Z, Yang L, Sun Z, Rong Y, Bai C, Dong Q, Jian L
Cancer biology & therapy 2023 Dec 31;24(1):2281459
Cancer biology & therapy 2023 Dec 31;24(1):2281459
Function of m(5)C RNA methyltransferase NOP2 in high-grade serous ovarian cancer.
Yang S, Zhou D, Zhang C, Xiang J, Xi X
Cancer biology & therapy 2023 Dec 31;24(1):2263921
Cancer biology & therapy 2023 Dec 31;24(1):2263921
Dexmedetomidine alleviates ferroptosis following hepatic ischemia-reperfusion injury by upregulating Nrf2/GPx4-dependent antioxidant responses.
Zhang Y, Wei H, Wang M, Yu Y, Gu M, Zhong H, Dong S
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Dec 31;169:115915
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Dec 31;169:115915
Preclinical evaluation of RQ3013, a broad-spectrum mRNA vaccine against SARS-CoV-2 variants.
Tan S, Zhao J, Hu X, Li Y, Wu Z, Lu G, Yu Z, Du B, Liu Y, Li L, Chen Y, Li Y, Yao Y, Zhang X, Rao J, Gao G, Peng Y, Liu H, Yuan Z, Liu J, Wang Q, Hu H, Gao X, Zhou H, Yu H, Xu Y, Yu W, Feng L, Wang M, Shan C, Lu J, Lin J
Science bulletin 2023 Dec 30;68(24):3192-3206
Science bulletin 2023 Dec 30;68(24):3192-3206
Matrine Targets BTF3 to Inhibit the Growth of Canine Mammary Tumor Cells.
Feng Z, Sun N, Noor F, Sun P, Zhang H, Zhong J, Yin W, Fan K, Yang H, Zhang Z, Sun Y, Li H
International journal of molecular sciences 2023 Dec 30;25(1)
International journal of molecular sciences 2023 Dec 30;25(1)
MicroRNA miR-212-5p Regulates the MEK/ERK Signaling Pathway by Targeting A-Raf proto-oncogene serine/threonine-protein kinase (ARAF) to Regulate Cowshed PM(2.5)-Induced NR8383 Apoptosis.
Sun K, Sun Y, Jia Y, Duan X, Ma Z, Zhang X, Wang L, Zhu Y, Gao Y, Basang W
Toxics 2023 Dec 3;11(12)
Toxics 2023 Dec 3;11(12)
Muscone inhibits angiotensin II-induced cardiac hypertrophy through the STAT3, MAPK and TGF-β/SMAD signaling pathways.
Liu YJ, Xu JJ, Yang C, Li YL, Chen MW, Liu SX, Zheng XH, Luo P, Li R, Xiao D, Shan ZG
Molecular biology reports 2023 Dec 29;51(1):39
Molecular biology reports 2023 Dec 29;51(1):39
Canthaxanthin Attenuates the Vascular Aging or Endothelial Cell Senescence by Inhibiting Inflammation and Oxidative Stress in Mice.
Wang Z, Li L, Liao S, Huang R, Jiang Y, Fei J, Cai L, Zhang K
Frontiers in bioscience (Landmark edition) 2023 Dec 29;28(12):367
Frontiers in bioscience (Landmark edition) 2023 Dec 29;28(12):367
Jian-Pi-Yi-Shen formula alleviates renal fibrosis by restoring NAD+ biosynthesis in vivo and in vitro.
Gao L, Huang X, Deng R, Wu S, Peng Y, Xiong G, Lu J, Liu X
Aging 2023 Dec 28;16(1):106-128
Aging 2023 Dec 28;16(1):106-128
Inhibition of TGF-β1-induced epithelial-mesenchymal transition in gliomas by DMC-HA.
Shi L, Wang Z, Rong J, Fei X, Li X, He B, Gong W, Qian J
Aging 2023 Dec 27;15(24):15183-15195
Aging 2023 Dec 27;15(24):15183-15195
GDF-15 Inhibits ADP-Induced Human Platelet Aggregation through the GFRAL/RET Signaling Complex.
Xie B, Tang W, Wen S, Chen F, Yang C, Wang M, Yang Y, Liang W
Biomolecules 2023 Dec 27;14(1)
Biomolecules 2023 Dec 27;14(1)
PDGFRα/β heterodimer activation negatively affects downstream ERK1/2 signaling and cellular proliferation.
Campaña MB, Perkins MR, McCabe MC, Neumann A, Larson ED, Fantauzzo KA
bioRxiv : the preprint server for biology 2023 Dec 27;
bioRxiv : the preprint server for biology 2023 Dec 27;
NLRP14 deficiency causes female infertility with oocyte maturation defects and early embryonic arrest by impairing cytoplasmic UHRF1 abundance.
Zhang W, Zhang R, Wu L, Zhu C, Zhang C, Xu C, Zhao S, Liu X, Guo T, Lu Y, Gao Z, Yu X, Li L, Chen ZJ, Qin Y, Jiao X
Cell reports 2023 Dec 26;42(12):113531
Cell reports 2023 Dec 26;42(12):113531
Cell-cell and cell-matrix adhesion regulated by Piezo1 is critical for stiffness-dependent DRG neuron aggregation.
Lei M, Wang W, Zhang H, Gong J, Wang Z, Cai H, Yang X, Wang S, Ma C
Cell reports 2023 Dec 26;42(12):113522
Cell reports 2023 Dec 26;42(12):113522
E3 ligase Trim35 inhibits LSD1 demethylase activity through K63-linked ubiquitination and enhances anti-tumor immunity in NSCLC.
Tang F, Lu C, He X, Lin W, Xie B, Gao X, Peng Y, Yang D, Sun L, Weng L
Cell reports 2023 Dec 26;42(12):113477
Cell reports 2023 Dec 26;42(12):113477
COPI Vesicle Disruption Inhibits Mineralization via mTORC1-Mediated Autophagy.
Nie J, Ma S, Zhang Y, Yu S, Yang J, Li A, Pei D
International journal of molecular sciences 2023 Dec 26;25(1)
International journal of molecular sciences 2023 Dec 26;25(1)
Selenium enhances photodynamic therapy of C-phycocyanin against lung cancer via dual regulation of cytotoxicity and antioxidant activity.
Shen J, Xia H, Zhou X, Zhang L, Gao Q, He K, Liu D, Huang B
Acta biochimica et biophysica Sinica 2023 Dec 25;55(12):1925-1937
Acta biochimica et biophysica Sinica 2023 Dec 25;55(12):1925-1937
A Novel COCH p.D544Vfs*3 Variant Associated with DFNA9 Sensorineural Hearing Loss Causes Pathological Multimeric Cochlin Formation.
Peng Y, Xiang M, Fan T, Zhong X, Dai A, Feng J, Guan P, Gong J, Li J, Wang Y
Life (Basel, Switzerland) 2023 Dec 25;14(1)
Life (Basel, Switzerland) 2023 Dec 25;14(1)
GM-CSF improves endometrial receptivity in a thin endometrium rat model by upregulating HOXA10.
Wei W, Wang N, Zhu Y, Liao M, Wang B, Du T, Zhang J, Mao X
Molecular human reproduction 2023 Dec 24;30(1)
Molecular human reproduction 2023 Dec 24;30(1)
The Role of DNMT1 and C/EBPα in the Regulation of CYP11A1 Expression During Syncytialization of Human Placental Trophoblasts.
Zhu YN, Pan F, Gan XW, Liu Y, Wang WS, Sun K
Endocrinology 2023 Dec 23;165(2)
Endocrinology 2023 Dec 23;165(2)
MNX1 Promotes Anti-HER2 Therapy Sensitivity via Transcriptional Regulation of CD-M6PR in HER2-Positive Breast Cancer.
Chi W, Xiu B, Xiong M, Wang X, Li P, Zhang Q, Hou J, Sang Y, Zhou X, Chen M, Zheng S, Zhang L, Xue J, Chi Y, Wu J
International journal of molecular sciences 2023 Dec 22;25(1)
International journal of molecular sciences 2023 Dec 22;25(1)
Amino acid substitutions in norovirus VP1 dictate host dissemination via variations in cellular attachment.
Mills JT, Minogue SC, Snowden JS, Arden WKC, Rowlands DJ, Stonehouse NJ, Wobus CE, Herod MR
Journal of virology 2023 Dec 21;97(12):e0171923
Journal of virology 2023 Dec 21;97(12):e0171923
The role of lysosomes as intermediates in betacoronavirus PHEV egress from nerve cells.
Wang Z, He W, Li C, Chen Y, Li Z, Jiao Y, Zhang J, Shi J, Wang G, Guan J, Zhao K, Song D, Gao F, Lan Y
Journal of virology 2023 Dec 21;97(12):e0133823
Journal of virology 2023 Dec 21;97(12):e0133823
Hsa_circ_0007321 regulates Zika virus replication through miR-492/NFKBID/NF-κB signaling pathway.
Kang L, Xie H, Ye H, Jeyarajan AJ, Warner CA, Huang Y, Shi Y, Li Y, Yang C, Xu M, Lin W, Sun J, Chen L, Duan X, Li S
Journal of virology 2023 Dec 21;97(12):e0123223
Journal of virology 2023 Dec 21;97(12):e0123223
ZDHHC5-mediated NLRP3 palmitoylation promotes NLRP3-NEK7 interaction and inflammasome activation.
Zheng S, Que X, Wang S, Zhou Q, Xing X, Chen L, Hou C, Ma J, An P, Peng Y, Yao Y, Song Q, Li J, Zhang P, Pei H
Molecular cell 2023 Dec 21;83(24):4570-4585.e7
Molecular cell 2023 Dec 21;83(24):4570-4585.e7
m(6)A modification negatively regulates translation by switching mRNA from polysome to P-body via IGF2BP3.
Shan T, Liu F, Wen M, Chen Z, Li S, Wang Y, Cheng H, Zhou Y
Molecular cell 2023 Dec 21;83(24):4494-4508.e6
Molecular cell 2023 Dec 21;83(24):4494-4508.e6
SIRT3 Regulates Levels of Deacetylated SOD2 to Prevent Oxidative Stress and Mitochondrial Dysfunction During Oocyte Maturation in Pigs.
Jiao L, Hu CX, Zhang Y, Zhang YX, Cai WW, Pan WL, Sun SC, Zhang Y
Microscopy and microanalysis : the official journal of Microscopy Society of America, Microbeam Analysis Society, Microscopical Society of Canada 2023 Dec 21;29(6):2149-2160
Microscopy and microanalysis : the official journal of Microscopy Society of America, Microbeam Analysis Society, Microscopical Society of Canada 2023 Dec 21;29(6):2149-2160
Schistosome egg-derived extracellular vesicles deliver Sja-miR-71a inhibits host macrophage and neutrophil extracellular traps via targeting Sema4D.
Liao Y, Zhu Z, Liu Y, Wu J, Li D, Li Z, Xu J, Yang R, Wang L
Cell communication and signaling : CCS 2023 Dec 21;21(1):366
Cell communication and signaling : CCS 2023 Dec 21;21(1):366
m(6)A methylation-mediated PGC-1α contributes to ferroptosis via regulating GSTK1 in arsenic-induced hepatic insulin resistance.
Zhang J, Song J, Liu S, Zhang Y, Qiu T, Jiang L, Bai J, Yao X, Wang N, Yang G, Sun X
The Science of the total environment 2023 Dec 20;905:167202
The Science of the total environment 2023 Dec 20;905:167202
EphB6 deficiency in intestinal neurons promotes tumor growth in colorectal cancer by neurotransmitter GABA signaling.
Yu H, Qin XK, Yin KW, Li ZM, Ni ED, Yang JM, Liu XH, Zhou AJ, Li SJ, Gao TM, Li Y, Li JM
Carcinogenesis 2023 Dec 2;44(8-9):682-694
Carcinogenesis 2023 Dec 2;44(8-9):682-694
Metabolites-Based Network Pharmacology to Preliminarily Verify In Vitro Anti-Inflammatory Effect of Ardisiacrispin B.
Zhou W, Yang G, Wen Y, Xiao Q, Sun L, Li Y, Gong Z, Wang Y
International journal of molecular sciences 2023 Dec 2;24(23)
International journal of molecular sciences 2023 Dec 2;24(23)
Circular RNA circEYA3 promotes the radiation resistance of hepatocellular carcinoma via the IGF2BP2/DTX3L axis.
Hu P, Lin L, Huang T, Li Z, Xiao M, Guo H, Chen G, Liu D, Ke M, Shan H, Zhang F, Zhang Y
Cancer cell international 2023 Dec 2;23(1):308
Cancer cell international 2023 Dec 2;23(1):308
ESRP1-driven alternative splicing of CLSTN1 inhibits the metastasis of gastric cancer.
Li C, Yin Y, Tao R, Lin Y, Wang T, Shen Q, Li R, Tao K, Liu W
Cell death discovery 2023 Dec 19;9(1):464
Cell death discovery 2023 Dec 19;9(1):464
Engineering irradiated tumor-derived microparticles as personalized vaccines to enhance anti-tumor immunity.
Sun Y, Tian Y, Wu S, Huang A, Hu Y, Liao Z, Swift M, Deng S, Yang X, Zhang B, Zhang Z, Wu B, Huang J, Jiang K, Huang F, Jin H, Wan C, Yang K
Cell reports. Medicine 2023 Dec 19;4(12):101303
Cell reports. Medicine 2023 Dec 19;4(12):101303
Regulation of the WNT-CTNNB1 signaling pathway by severe fever with thrombocytopenia syndrome virus in a cap-snatching manner.
Jiang X-M, Xin Q-L, Liu K, Peng X-F, Han S, Zhang L-Y, Liu W, Xiao G-F, Li H, Zhang L-K
mBio 2023 Dec 19;14(6):e0168823
mBio 2023 Dec 19;14(6):e0168823
Lentiviral mediated delivery of CRISPR/Cas9 reduces intraocular pressure in a mouse model of myocilin glaucoma.
Patil SV, Kaipa BR, Ranshing S, Sundaresan Y, Millar JC, Nagarajan B, Kiehlbauch C, Zhang Q, Jain A, Searby CC, Scheetz TE, Clark AF, Sheffield VC, Zode GS
Research square 2023 Dec 19;
Research square 2023 Dec 19;
A novel de novo CLTC variant altering RNA splicing causes fetal developmental abnormalities.
Cheng C, Yang F, Zhao S, Chen X
BMC medical genomics 2023 Dec 18;16(1):331
BMC medical genomics 2023 Dec 18;16(1):331
Amyloid precursor protein induces reactive astrogliosis.
Jauregui GV, Vukić D, Onyango IG, Arias C, Novotný JS, Texlová K, Wang S, Kovačovicova KL, Polakova N, Zelinkova J, Čarna M, Strašil VL, Head BP, Havas D, Mistrik M, Zorec R, Verkhratsky A, Keegan L, O'Connel M, Rissman R, Stokin GB
bioRxiv : the preprint server for biology 2023 Dec 18;
bioRxiv : the preprint server for biology 2023 Dec 18;
Dapoxetine, a Selective Serotonin Reuptake Inhibitor, Suppresses Zika Virus Infection In Vitro.
Zhang B, Yu J, Zhu G, Huang Y, Zhang K, Xiao X, He W, Yuan J, Gao X
Molecules (Basel, Switzerland) 2023 Dec 17;28(24)
Molecules (Basel, Switzerland) 2023 Dec 17;28(24)
Dexmedetomidine alleviates renal tubular ferroptosis in sepsis-associated AKI by KEAP1 regulating the degradation of GPX4.
Li J, Liu Y, Bai J, Liu T, Qin X, Hu T, Wang S, Li Y, Cui S, Quan Z, Luo Y, Zheng J, Wang H
European journal of pharmacology 2023 Dec 15;961:176194
European journal of pharmacology 2023 Dec 15;961:176194
Glycyrrhetinic acid attenuates endoplasmic reticulum stress-induced hepatocyte apoptosis via CHOP/DR5/Caspase 8 pathway in cholestasis.
Zou B, Zhang S, Zhao J, Song G, Weng F, Xu X, Li F, Jin J, Yan D, Huang K, Liu C, Li Y, Qiu F
European journal of pharmacology 2023 Dec 15;961:176193
European journal of pharmacology 2023 Dec 15;961:176193
Repositioning of Montelukast to inhibit proliferation of mutated KRAS pancreatic cancer through a novel mechanism that interfere the binding between KRAS and GTP/GDP.
Xia Y, Zhang S, Luo H, Wang Y, Jiang Y, Jiang J, Yuan S
European journal of pharmacology 2023 Dec 15;961:176157
European journal of pharmacology 2023 Dec 15;961:176157
NAMPT mediates PDGF-induced pulmonary arterial smooth muscle cell proliferation by TLR4/NF-κB/PLK4 signaling pathway.
Li D, Chen Y, Wang Y, Liu J, Chai L, Zhang Q, Qiu Y, Chen H, Shen N, Shi X, Li M
European journal of pharmacology 2023 Dec 15;961:176151
European journal of pharmacology 2023 Dec 15;961:176151
Targeted clearance of mitochondria by an autophagy-tethering compound (ATTEC) and its potential therapeutic effects.
Tan S, Wang D, Fu Y, Zheng H, Liu Y, Lu B
Science bulletin 2023 Dec 15;68(23):3013-3026
Science bulletin 2023 Dec 15;68(23):3013-3026
Anti-inflammatory effect of two novel peptides derived from Binglangjiang buffalo whey protein in lipopolysaccharide-stimulated RAW264.7 macrophages.
Zhao Q, Zheng W, Yuan Z, Wang X, Huang A
Food chemistry 2023 Dec 15;429:136804
Food chemistry 2023 Dec 15;429:136804
Mechanism of Huaiqihuang in treatment of diabetic kidney disease based on network pharmacology, molecular docking and in vitro experiment.
Wang J, Ma G, Zhang P, Ma C, Shao J, Wang L, Ma C
Medicine 2023 Dec 15;102(50):e36177
Medicine 2023 Dec 15;102(50):e36177
Discovery of a Dual Tubulin and Neuropilin-1 (NRP1) Inhibitor with Potent In Vivo Anti-Tumor Activity via Pharmacophore-based Docking Screening, Structure Optimization, and Biological Evaluation.
Zheng L, Zou Y, Xie T, Wu X, Tan Y, Mei S, Geng Y, Chen S, Xu S, Niu MM
Journal of medicinal chemistry 2023 Dec 14;66(23):16187-16200
Journal of medicinal chemistry 2023 Dec 14;66(23):16187-16200
Discovery of Pyrazolo[1,5-a]pyrimidine Derivative as a Novel and Selective ALKBH5 Inhibitor for the Treatment of AML.
Wang YZ, Li HY, Zhang Y, Jiang RX, Xu J, Gu J, Jiang Z, Jiang ZY, You QD, Guo XK
Journal of medicinal chemistry 2023 Dec 14;66(23):15944-15959
Journal of medicinal chemistry 2023 Dec 14;66(23):15944-15959
Aloin Attenuates Oxidative Stress, Inflammation, and CCl(4)-Induced Liver Fibrosis in Mice: Possible Role of TGF-β/Smad Signaling.
Bai J, Qian B, Cai T, Chen Y, Li T, Cheng Y, Wu Z, Liu C, Ye M, Du Y, Fu W
Journal of agricultural and food chemistry 2023 Dec 13;71(49):19475-19487
Journal of agricultural and food chemistry 2023 Dec 13;71(49):19475-19487
Efficacy and mechanism of Shenqi Compound in inhibiting diabetic vascular calcification.
Yang C, Xie Z, Liu H, Wang X, Zhang Z, Du L, Xie C
Molecular medicine (Cambridge, Mass.) 2023 Dec 13;29(1):168
Molecular medicine (Cambridge, Mass.) 2023 Dec 13;29(1):168
A positive feedback circuit driven by m(6)A-modified circular RNA facilitates colorectal cancer liver metastasis.
Zeng K, Peng J, Xing Y, Zhang L, Zeng P, Li W, Zhang W, Pan Z, Zhou C, Lin J
Molecular cancer 2023 Dec 13;22(1):202
Molecular cancer 2023 Dec 13;22(1):202
Histone demethylase KDM4B accelerates the progression of glioblastoma via the epigenetic regulation of MYC stability.
Wang Z, Cai H, Li Z, Sun W, Zhao E, Cui H
Clinical epigenetics 2023 Dec 13;15(1):192
Clinical epigenetics 2023 Dec 13;15(1):192
The development of a hiPSC-based platform to identify tissue-dependencies of IDH1 R132H.
Mehjardi NZ, Kessler J, Sanin AY, Picard D, Westhoff P, Nickel AC, Uhlmann C, Shi W, Steiger HJ, Remke M, Fischer I, Vordermark D, Croner RS, Kahlert UD
Cell death discovery 2023 Dec 12;9(1):452
Cell death discovery 2023 Dec 12;9(1):452
Reduced Proteolipid Protein 2 promotes endoplasmic reticulum stress-related apoptosis and increases drug sensitivity in acute myeloid leukemia.
Xie F, Qu J, Lin D, Feng K, Tan M, Liao H, Zeng L, Xiong Q, Huang J, Chen W
Molecular biology reports 2023 Dec 12;51(1):10
Molecular biology reports 2023 Dec 12;51(1):10
Alleviation of ischemia-reperfusion induced renal injury by chemically modified SOD2 mRNA delivered via lipid nanoparticles.
Hou Y, Lin S, Xia J, Zhang Y, Yin Y, Huang M, Xu Y, Yang W, Zhu Y
Molecular therapy. Nucleic acids 2023 Dec 12;34:102067
Molecular therapy. Nucleic acids 2023 Dec 12;34:102067
Efficacy of exon-skipping therapy for DMD cardiomyopathy with mutations in actin binding domain 1.
Shiba N, Yang X, Sato M, Kadota S, Suzuki Y, Agata M, Nagamine K, Izumi M, Honda Y, Koganehira T, Kobayashi H, Ichimura H, Chuma S, Nakai J, Tohyama S, Fukuda K, Miyazaki D, Nakamura A, Shiba Y
Molecular therapy. Nucleic acids 2023 Dec 12;34:102060
Molecular therapy. Nucleic acids 2023 Dec 12;34:102060
Transition of allele-specific DNA hydroxymethylation at regulatory loci is associated with phenotypic variation in monozygotic twins discordant for psychiatric disorders.
Ye J, Huang Z, Li Q, Li Z, Lan Y, Wang Z, Ni C, Wu X, Jiang T, Li Y, Yang Q, Lim J, Ren CY, Jiang M, Li S, Jin P, Chen JH, Zhao C
BMC medicine 2023 Dec 12;21(1):491
BMC medicine 2023 Dec 12;21(1):491
Hepatic Stellate Cell- and Liver Microbiome-Specific Delivery System for Dihydrotanshinone I to Ameliorate Liver Fibrosis.
Niu X, Meng Y, Cui J, Li R, Ding X, Niu B, Chang G, Xu N, Li G, Wang Y, Wang L
ACS nano 2023 Dec 12;17(23):23608-23625
ACS nano 2023 Dec 12;17(23):23608-23625
Nuclear cGAS restricts L1 retrotransposition by promoting TRIM41-mediated ORF2p ubiquitination and degradation.
Zhen Z, Chen Y, Wang H, Tang H, Zhang H, Liu H, Jiang Y, Mao Z
Nature communications 2023 Dec 12;14(1):8217
Nature communications 2023 Dec 12;14(1):8217
Diversity for endoribonuclease nsp15-mediated regulation of alpha-coronavirus propagation and virulence.
Xie Y, Chen C, Zhang D, Jiao Z, Chen Y, Wang G, Tan Y, Zhang W, Xiao S, Peng G, Shi Y
Microbiology spectrum 2023 Dec 12;11(6):e0220923
Microbiology spectrum 2023 Dec 12;11(6):e0220923
Glaesserella parasuis QseBC two-component system senses epinephrine and regulates capD expression.
Sun J, Wen S, Wang Z, Liu W, Lin Y, Gu J, Mao W, Xu X, He Q, Cai X
Microbiology spectrum 2023 Dec 12;11(6):e0150823
Microbiology spectrum 2023 Dec 12;11(6):e0150823
Dissecting T-cell heterogeneity in esophageal squamous cell carcinoma reveals the potential role of LAIR2 in antitumor immunity.
Wang P, Zhuang W, Zheng Z, Zhang L, Zhang X, Chen Q
Clinical and experimental immunology 2023 Dec 11;214(1):36-49
Clinical and experimental immunology 2023 Dec 11;214(1):36-49
The Arabidopsis ubiquitin ligases ATL31 and ATL6 regulate plant response to salt stress in an ABA-independent manner.
Du M, Lu D, Liu X
Biochemical and biophysical research communications 2023 Dec 10;685:149156
Biochemical and biophysical research communications 2023 Dec 10;685:149156
Co-exposure to molybdenum and cadmium evokes necroptosis and decreases apoptosis in duck myocardium.
Liu H, Dai X, Xu S, Guo H, Zhu J, Wang S, Wu Y, Zhang C
The Science of the total environment 2023 Dec 1;902:166074
The Science of the total environment 2023 Dec 1;902:166074
TMEM44-AS1 promotes esophageal squamous cell carcinoma progression by regulating the IGF2BP2-GPX4 axis in modulating ferroptosis.
Yang R, Wan J, Ma L, Zhou F, Yang Z, Li Z, Zhang M, Ming L
Cell death discovery 2023 Dec 1;9(1):431
Cell death discovery 2023 Dec 1;9(1):431
Fatty Acid Oxidation Mediated by Malonyl-CoA Decarboxylase Represses Renal Cell Carcinoma Progression.
Zhou L, Luo Y, Liu Y, Zeng Y, Tong J, Li M, Hou Y, Du K, Qi Y, Pan W, Liu Y, Wang R, Tian F, Gu C, Chen K
Cancer research 2023 Dec 1;83(23):3920-3939
Cancer research 2023 Dec 1;83(23):3920-3939
Phosphatidylinositol-specific phospholipase C can decrease Müller cell viability and suppress its phagocytic activity by modulating PI3K/AKT signaling pathway.
Sun B, Lin S, Zheng M, Zheng B, Mao L, Gu Y, Cai J, Dai Y, Zheng M, Lou Y
Canadian journal of microbiology 2023 Dec 1;69(12):501-511
Canadian journal of microbiology 2023 Dec 1;69(12):501-511
TP induces hepatic intolerance to FasL-mediated hepatocyte apoptosis by inhibiting XIAP.
Fan X, Zhu Y, Peng S, Miao Y, Lu Q, Zhang L, Jiang Z, Yu Q
Toxicology letters 2023 Dec 1;390:25-32
Toxicology letters 2023 Dec 1;390:25-32
The role of ROS-pyroptosis in PM(2.5) induced air-blood barrier destruction.
Wei M, Cong Y, Lei J, Du R, Yang M, Lu X, Jiang Y, Cao R, Meng X, Jiang Z, Song L
Chemico-biological interactions 2023 Dec 1;386:110782
Chemico-biological interactions 2023 Dec 1;386:110782
Pectolinarigenin attenuates hepatic ischemia/reperfusion injury via activation of the PI3K/AKT/Nrf2 signaling pathway.
Li H, Chen Y, Ding M, Yan Z, Guo W, Guo R
Chemico-biological interactions 2023 Dec 1;386:110763
Chemico-biological interactions 2023 Dec 1;386:110763
Metal transporter SLC39A14/ZIP14 modulates regulation between the gut microbiome and host metabolism.
Mitchell SB, Thorn TL, Lee MT, Kim Y, Comrie JMC, Bai ZS, Johnson EL, Aydemir TB
American journal of physiology. Gastrointestinal and liver physiology 2023 Dec 1;325(6):G593-G607
American journal of physiology. Gastrointestinal and liver physiology 2023 Dec 1;325(6):G593-G607
Covalent Targeting of Glutamate Cysteine Ligase to Inhibit Glutathione Synthesis.
Zhang LH, Tang M, Tao X, Shao Q, Thomas V, Shimizu S, Kasano M, Ishikawa Y, Inukai T, Nomura DK
Chembiochem : a European journal of chemical biology 2023 Dec 1;24(23):e202300371
Chembiochem : a European journal of chemical biology 2023 Dec 1;24(23):e202300371
AURKAIP1 actuates tumor progression through stabilizing DDX5 in triple negative breast cancer.
Tian W, Tang Y, Luo Y, Xie J, Zheng S, Zou Y, Huang X, Wu L, Zhang J, Sun Y, Tang H, Du W, Li X, Xie X
Cell death & disease 2023 Dec 1;14(12):790
Cell death & disease 2023 Dec 1;14(12):790
Modeling aging and retinal degeneration with mitochondrial DNA mutation burden.
Sturgis J, Singh R, Caron Q, Samuels IS, Shiju TM, Mukkara A, Freedman P, Bonilha VL
bioRxiv : the preprint server for biology 2023 Dec 1;
bioRxiv : the preprint server for biology 2023 Dec 1;
Air-ventilated normothermic machine perfusion alleviates hepatic injury from DCD rat through CYP1A2.
Shi JH, Cheng N, Zhang W, Jin Q, Guo WZ, Ge GB, Zhang SJ, Line PD, Wang Y
Heliyon 2023 Aug;9(8):e19150
Heliyon 2023 Aug;9(8):e19150
Metformin promotes cGAS/STING signaling pathway activation by blocking AKT phosphorylation in gastric cancer.
Shen Q, Yang L, Li C, Wang T, Lv J, Liu W, Lin Y, Yin Y, Tao K
Heliyon 2023 Aug;9(8):e18954
Heliyon 2023 Aug;9(8):e18954
The Expression of ZNF268 and Its Role in The Cisplatin-based Chemoresistance of Breast Cancer.
Wu W, Yao S, Huang J, Qing J, Shi Q, Huang J, Qiu X, Zhuang Y
Heliyon 2023 Aug;9(8):e18779
Heliyon 2023 Aug;9(8):e18779
Guf1 overexpression improves pancreatic β cell functions in type 2 diabetes mellitus rats with Roux-en-Y gastric bypass (RYGB) surgery.
Li P, Dai S, Gao X, Li W
Journal of physiology and biochemistry 2023 Aug;79(3):569-582
Journal of physiology and biochemistry 2023 Aug;79(3):569-582
The increased expression of cytokeratin 13 leads to an increase in radiosensitivity of nasopharyngeal carcinoma HNE-3 cells by upregulating ERRFI1.
Wang H, Shi M, Wan J, Yu H
IUBMB life 2023 Aug;75(8):688-698
IUBMB life 2023 Aug;75(8):688-698
Promotion of hepatic stellate cell activation and liver fibrosis by microRNA-33a-5p through targeting the Dickkopf-1-mediated wingless-related integration site/beta-catenin pathway.
Liu H, Zhang S, Li Z, Zheng Z, Shi W, Hu M, Liu F
Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 2023 Aug;74(4)
Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 2023 Aug;74(4)
Huoxue Jiedu Recipe represses mitochondrial fission to alleviate submandibular gland inflammation in Sjögren's syndrome.
Xu J, Shen Z, Du Y, Zhang S, Xi Y, Zhang Y, Wang D, Zhu Y
Microbiology and immunology 2023 Aug;67(8):377-387
Microbiology and immunology 2023 Aug;67(8):377-387
Pantethine Ameliorates Recognition Impairment in a Mouse Model of Alzheimer's Disease by Modulating Cholesterol Content and Intestinal Flora Species.
Chen J, Li Y, Chen M, Liu X, Chen J, Li X, Wang C, Wan G, Tian J
Molecular nutrition & food research 2023 Aug;67(15):e2200799
Molecular nutrition & food research 2023 Aug;67(15):e2200799
CircRNA Galntl6 sponges miR-335 to ameliorate stress-induced hypertension through upregulating Lig3 in rostral ventrolateral medulla.
Zhang S, Wang X, Chen G, Tong L, Dai T, Wang L, Zhu L, Zhang H, Du D
Redox biology 2023 Aug;64:102782
Redox biology 2023 Aug;64:102782
NOX2 inhibition stabilizes vulnerable plaques by enhancing macrophage efferocytosis via MertK/PI3K/AKT pathway.
Wang Y, Liu XY, Wang Y, Zhao WX, Li FD, Guo PR, Fan Q, Wu XF
Redox biology 2023 Aug;64:102763
Redox biology 2023 Aug;64:102763
DYRK1A-mediated PLK2 phosphorylation regulates the proliferation and invasion of glioblastoma cells.
Tan S, Zhao J, Wang P
International journal of oncology 2023 Aug;63(2)
International journal of oncology 2023 Aug;63(2)
Overexpression of SERPINA3 suppresses tumor progression by modulating SPOP/NF‑κB in lung cancer.
Jin Y, Zhang Y, Huang A, Chen Y, Wang J, Liu N, Wang X, Gong Y, Wang W, Pan J
International journal of oncology 2023 Aug;63(2)
International journal of oncology 2023 Aug;63(2)
PRMT1 inhibition promotes ferroptosis sensitivity via ACSL1 upregulation in acute myeloid leukemia.
Zhou L, Jia X, Shang Y, Sun Y, Liu Z, Liu J, Jiang W, Deng S, Yao Q, Chen J, Li H
Molecular carcinogenesis 2023 Aug;62(8):1119-1135
Molecular carcinogenesis 2023 Aug;62(8):1119-1135
Theabrownin of raw and ripened pu-erh tea varies in the alleviation of HFD-induced obesity via the regulation of gut microbiota.
Deng X, Zhang N, Wang Q, Huang Y, Huang Y, Lin Y, Huang M, Zheng F, Xiao M, Ye J
European journal of nutrition 2023 Aug;62(5):2177-2194
European journal of nutrition 2023 Aug;62(5):2177-2194
Retinoic Acid Prevents α-Synuclein Preformed Fibrils-Induced Toxicity via Inhibiting STAT1-PARP1 Signaling.
Zhou L, Ma Z, Gao X
Molecular neurobiology 2023 Aug;60(8):4828-4841
Molecular neurobiology 2023 Aug;60(8):4828-4841
SCNN1B regulates the proliferation, migration, and collagen deposition of human lung fibroblasts.
Yan Y, Zhang Y, Zhang J, Ying L
In vitro cellular & developmental biology. Animal 2023 Aug;59(7):479-485
In vitro cellular & developmental biology. Animal 2023 Aug;59(7):479-485
MiR-590-5p promotes cisplatin resistance via targeting hMSH2 in ovarian cancer.
Li B, Xu X, Zheng L, Jiang X, Lin J, Zhang G
Molecular biology reports 2023 Aug;50(8):6819-6827
Molecular biology reports 2023 Aug;50(8):6819-6827
Effects of honokiol protects against chronic kidney disease via BNIP3/NIX and FUNDC1-mediated mitophagy and AMPK pathways.
Wei X, Wang Y, Lao Y, Weng J, Deng R, Li S, Lu J, Yang S, Liu X
Molecular biology reports 2023 Aug;50(8):6557-6568
Molecular biology reports 2023 Aug;50(8):6557-6568
Dipeptidase‑2 is a prognostic marker in lung adenocarcinoma that is correlated with its sensitivity to cisplatin.
Wang Y, Zhang T, Du H, Yang M, Xie G, Liu T, Deng S, Yuan W, He S, Wu D, Xu Y
Oncology reports 2023 Aug;50(2)
Oncology reports 2023 Aug;50(2)
CD44 Drives M1 Macrophage Polarization in Diabetic Retinopathy.
Pan Z, Zhao Y, Zhou S, Wang J, Fan F
Current eye research 2023 Aug;48(8):770-780
Current eye research 2023 Aug;48(8):770-780
UBP43 promotes epithelial ovarian carcinogenesis via activation of β-catenin signaling pathway.
Xie H, Chen J, Ma C, Zhao J, Cui M
Cell biology international 2023 Aug;47(8):1427-1440
Cell biology international 2023 Aug;47(8):1427-1440
PLAU contributes to the development of cholangiocarcinoma via activating NF-κB signaling pathway.
Hu MD, Jia LH, Wang ML
Cell biology international 2023 Aug;47(8):1381-1391
Cell biology international 2023 Aug;47(8):1381-1391
LPS-aggravated Ferroptosis via Disrupting Circadian Rhythm by Bmal1/AKT/p53 in Sepsis-Induced Myocardial Injury.
Lin H, Ji F, Lin KQ, Zhu YT, Yang W, Zhang LH, Zhao JG, Pei YH
Inflammation 2023 Aug;46(4):1133-1143
Inflammation 2023 Aug;46(4):1133-1143
Glutamine metabolic microenvironment drives M2 macrophage polarization to mediate trastuzumab resistance in HER2-positive gastric cancer.
Hu X, Ma Z, Xu B, Li S, Yao Z, Liang B, Wang J, Liao W, Lin L, Wang C, Zheng S, Wu Q, Huang Q, Yu L, Wang F, Shi M
Cancer communications (London, England) 2023 Aug;43(8):909-937
Cancer communications (London, England) 2023 Aug;43(8):909-937
Uncovering pharmacological mechanisms of Phellinus linteus on focal segmental glomeruloscleosis rats through tandem mass tag-based quantitative proteomic analysis, network pharmacology analysis and experimental validation.
Feng W, Ruchun Y, Yuewen T
Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan 2023 Aug;43(4):744-750
Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan 2023 Aug;43(4):744-750
Qizhi Jiangtang capsule activates podocyte autophagy in diabetic kidney disease by inhibiting phosphatidylinositol 3-kinase/protein kinase B/mammalian target of rapamycin pathways.
Zhaoan G, Lina S, Yingying L, Ruifeng LI, Chong L, Ke D, Jing S, Jun S
Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan 2023 Aug;43(4):667-675
Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan 2023 Aug;43(4):667-675
Phosphorylated PTTG1 switches its subcellular distribution and promotes β-catenin stabilization and subsequent transcription activity.
Zhang X, Wu N, Huang H, Li S, Liu S, Zhang R, Huang Y, Lyu H, Xiao S, Ali DW, Michalak M, Chen XZ, Zhou C, Tang J
Oncogene 2023 Aug;42(32):2439-2455
Oncogene 2023 Aug;42(32):2439-2455
Degradation of MYC by the mutant p53 reactivator drug, COTI-2 in breast cancer cells.
Tang M, Crown J, Duffy MJ
Investigational new drugs 2023 Aug;41(4):541-550
Investigational new drugs 2023 Aug;41(4):541-550
TRAF6 regulates autophagy and apoptosis of melanoma cells through c-Jun/ATG16L2 signaling pathway.
Guo Y, Zhang X, Li J, Zhou Z, Zhu S, Liu W, Su J, Chen X, Peng C
MedComm 2023 Aug;4(4):e309
MedComm 2023 Aug;4(4):e309
The histone acetyltransferase Mof regulates Runx2 and Osterix for osteoblast differentiation.
Chen J, Liu D, Chen B, Yang Y, Zhu H, Li D, Liu K, Zhu L, Liu H, Li M, Zhang X, Li X
Cell and tissue research 2023 Aug;393(2):265-279
Cell and tissue research 2023 Aug;393(2):265-279
Activation of cDCs and iNKT cells contributes to triptolide-induced hepatotoxicity via STING signaling pathway and endoplasmic reticulum stress.
Chen X, Yu Z, Nong C, Xue R, Zhang M, Zhang Y, Sun L, Zhang L, Wang X
Cell biology and toxicology 2023 Aug;39(4):1753-1772
Cell biology and toxicology 2023 Aug;39(4):1753-1772
SIRT6 regulates obesity-induced oxidative stress via ENDOG/SOD2 signaling in the heart.
Gao S, Yang Q, Peng Y, Kong W, Liu Z, Li Z, Chen J, Bao M, Li X, Zhang Y, Bian X, Jin L, Zhang H, Zhang Y, Sanchis D, Yan F, Ye J
Cell biology and toxicology 2023 Aug;39(4):1489-1507
Cell biology and toxicology 2023 Aug;39(4):1489-1507
Exposure to MoS2 nanosheets or bulk activated Kruppel-like factor 4 in 3D Caco-2 spheroids in vitro and mouse intestines in vivo.
Xiao Y, He Y, Xu C, Li M, Hu F, Wang W, Wang Z, Cao Y
Environmental toxicology 2023 Aug;38(8):1925-1938
Environmental toxicology 2023 Aug;38(8):1925-1938
Farnesoid X receptor is an important target for the treatment of disorders of bile acid and fatty acid metabolism in mice with nonalcoholic fatty liver disease combined with cholestasis.
Liu X, Wang J, Li M, Qiu J, Li X, Qi L, Liu J, Liu P, Xie G, Wang X
Journal of gastroenterology and hepatology 2023 Aug;38(8):1438-1446
Journal of gastroenterology and hepatology 2023 Aug;38(8):1438-1446
Construction of coxsackievirus B5 viruses with luciferase reporters and their applications in vitro and in vivo.
Guo S, Xun M, Fan T, Li X, Yao H, Li X, Wu B, Yang H, Ma C, Wang H
Virologica Sinica 2023 Aug;38(4):549-558
Virologica Sinica 2023 Aug;38(4):549-558
RNF167-mediated ubiquitination of Tollip inhibits TNF-α-triggered NF-κB and MAPK activation.
Yan Z, Dai J, Wang J, Feng Q, Wang Y, Han T, Wu C
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Aug;37(8):e23089
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Aug;37(8):e23089
Role of FBXL5 in redox homeostasis and spindle assembly during oocyte maturation in mice.
Wang S, Wu X, Wang H, Song S, Hu Y, Guo Y, Chang S, Cheng Y, Zeng S
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Aug;37(8):e23080
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Aug;37(8):e23080
Dapagliflozin inhibits the activity of lateral habenula to alleviate diabetes mellitus-induced depressive-like behavior.
Dong D, Liu X, Ma L, Hao YL, Zhang L, Song M, Xu Z, Zhao H
Experimental neurology 2023 Aug;366:114448
Experimental neurology 2023 Aug;366:114448
USP39-mediated deubiquitination of Cyclin B1 promotes tumor cell proliferation and glioma progression.
Xiao Y, Chen X, Hu W, Ma W, Di Q, Tang H, Zhao X, Huang G, Chen W
Translational oncology 2023 Aug;34:101713
Translational oncology 2023 Aug;34:101713
Bone marrow mesenchymal stem cell-derived exosomal miR-193b-5p reduces pyroptosis after ischemic stroke by targeting AIM2.
Wang Y, Chen H, Fan X, Xu C, Li M, Sun H, Song J, Jia F, Wei W, Jiang F, Li G, Zhong D
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association 2023 Aug;32(8):107235
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association 2023 Aug;32(8):107235
The potential oncogenic effect of tissue-specific expression of JC polyoma T antigen in digestive epithelial cells.
Zheng HC, Xue H, Sun HZ, Yun WJ, Cui ZG
Transgenic research 2023 Aug;32(4):305-319
Transgenic research 2023 Aug;32(4):305-319
Divergent roles of estrogen receptor subtypes in regulating estrogen-modulated colonic ion transports and epithelial repair.
Wan H, Li J, Chen X, Sellers ZM, Dong H
The Journal of biological chemistry 2023 Aug;299(8):105068
The Journal of biological chemistry 2023 Aug;299(8):105068
Deubiquitinase USP9X stabilizes RNA m(6)A demethylase ALKBH5 and promotes acute myeloid leukemia cell survival.
Wang P, Wang J, Yao S, Cui M, Cheng Y, Liu W, Gao Z, Hu J, Zhang J, Zhang H
The Journal of biological chemistry 2023 Aug;299(8):105055
The Journal of biological chemistry 2023 Aug;299(8):105055
Repair of topoisomerase 1-induced DNA damage by tyrosyl-DNA phosphodiesterase 2 (TDP2) is dependent on its magnesium binding.
Shimizu N, Hamada Y, Morozumi R, Yamamoto J, Iwai S, Sugiyama KI, Ide H, Tsuda M
The Journal of biological chemistry 2023 Aug;299(8):104988
The Journal of biological chemistry 2023 Aug;299(8):104988
The RNA-binding protein ZC3H11A interacts with the nuclear poly(A)-binding protein PABPN1 and alters polyadenylation of viral transcripts.
Kases K, Schubert E, Hajikhezri Z, Larsson M, Devi P, Darweesh M, Andersson L, Akusjärvi G, Punga T, Younis S
The Journal of biological chemistry 2023 Aug;299(8):104959
The Journal of biological chemistry 2023 Aug;299(8):104959
ZBTB7A regulates primed-to-naïve transition of pluripotent stem cells via recognition of the PNT-associated sequence by zinc fingers 1-2 and recognition of γ-globin -200 gene element by zinc fingers 1-4.
Yang Y, Xiao L, Xue Y, Idris MO, Liu J, Pei D, Shi Y, Liao B, Li F
The FEBS journal 2023 Aug;290(15):3896-3909
The FEBS journal 2023 Aug;290(15):3896-3909
RNA m5C methylation orchestrates BLCA progression via macrophage reprogramming.
Yan D, Xie Y, Huang L, Zhang Y, Gu R, Xie H, Huang X, Luo H
Journal of cellular and molecular medicine 2023 Aug;27(16):2398-2411
Journal of cellular and molecular medicine 2023 Aug;27(16):2398-2411
The formation of migrasomes is initiated by the assembly of sphingomyelin synthase 2 foci at the leading edge of migrating cells.
Liang H, Ma X, Zhang Y, Liu Y, Liu N, Zhang W, Chen J, Liu B, Du W, Liu X, Yu L
Nature cell biology 2023 Aug;25(8):1173-1184
Nature cell biology 2023 Aug;25(8):1173-1184
Hyperuricemia promotes the progression of atherosclerosis by activating endothelial cell pyroptosis via the ROS/NLRP3 pathway.
He B, Nie Q, Wang F, Wang X, Zhou Y, Wang C, Guo J, Fan X, Ye Z, Liu P, Wen J
Journal of cellular physiology 2023 Aug;238(8):1808-1822
Journal of cellular physiology 2023 Aug;238(8):1808-1822
Loss of TDP-43 promotes somatic CAG repeat expansion in Huntington's disease knock-in mice.
Bai D, Zhu L, Jia Q, Duan X, Chen L, Wang X, Hou J, Jiang G, Yang S, Li S, Li XJ, Yin P
Progress in neurobiology 2023 Aug;227:102484
Progress in neurobiology 2023 Aug;227:102484
Trastuzumab potentiates doxorubicin-induced cardiotoxicity via activating the NLRP3 inflammasome in vivo and in vitro.
Wei S, Ma W, Yang Y, Sun T, Jiang C, Liu J, Zhang B, Li W
Biochemical pharmacology 2023 Aug;214:115662
Biochemical pharmacology 2023 Aug;214:115662
Anti-inflammatory iridoid glycosides from Paederia scandens (Lour.) Merrill.
Xu Y, Zeng J, Wang L, Xu J, He X, Wang Y
Phytochemistry 2023 Aug;212:113705
Phytochemistry 2023 Aug;212:113705
Difenoconazole disrupts carp intestinal physical barrier and causes inflammatory response via triggering oxidative stress and apoptosis.
Wu X, Han H, Xie K, He N, Yang Z, Jin X, Ma S, Dong J
Pesticide biochemistry and physiology 2023 Aug;194:105507
Pesticide biochemistry and physiology 2023 Aug;194:105507
The MGF300-2R protein of African swine fever virus is associated with viral pathogenicity by promoting the autophagic degradation of IKKα and IKKβ through the recruitment of TOLLIP.
Wang T, Luo R, Zhang J, Lu Z, Li LF, Zheng YH, Pan L, Lan J, Zhai H, Huang S, Sun Y, Qiu HJ
PLoS pathogens 2023 Aug;19(8):e1011580
PLoS pathogens 2023 Aug;19(8):e1011580
Dectin-1 deficiency alleviates diabetic cardiomyopathy by attenuating macrophage-mediated inflammatory response.
Yang N, Wang M, Lin K, Wang M, Xu D, Han X, Zhao X, Wang Y, Wu G, Luo W, Liang G, Shan P
Biochimica et biophysica acta. Molecular basis of disease 2023 Aug;1869(6):166710
Biochimica et biophysica acta. Molecular basis of disease 2023 Aug;1869(6):166710
The Warburg micro syndrome protein RAB3GAP1 modulates neuronal morphogenesis and interacts with axon elongation end ER-Golgi trafficking factors.
Ghate PS, Vacharasin JM, Ward JA, Nowling D, Kay V, Cowen MH, Lawlor MK, McCord M, Xu H, Carmona E, Cheon SH, Chukwurah E, Walla M, Lizarraga SB
Neurobiology of disease 2023 Aug;184:106215
Neurobiology of disease 2023 Aug;184:106215
3D artificial sebocyte glands from inertial focusing effect for facile and flexible analysis of light damage and drug screening.
Tang T, Wei Y, Jia H, Wang L, Xu Y, Zhang P
Biotechnology journal 2023 Aug;18(8):e2200634
Biotechnology journal 2023 Aug;18(8):e2200634
Non-invasive activation of intratumoural gene editing for improved adoptive T-cell therapy in solid tumours.
Chen X, Wang S, Chen Y, Xin H, Zhang S, Wu D, Xue Y, Zha M, Li H, Li K, Gu Z, Wei W, Ping Y
Nature nanotechnology 2023 Aug;18(8):933-944
Nature nanotechnology 2023 Aug;18(8):933-944
Exendin-4 and linagliptin attenuate neuroinflammation in a mouse model of Parkinson's disease.
Yu HY, Sun T, Wang Z, Li H, Xu D, An J, Wen LL, Li JY, Li W, Feng J
Neural regeneration research 2023 Aug;18(8):1818-1826
Neural regeneration research 2023 Aug;18(8):1818-1826
Triclocarban exposure aggravates dextran sulfate sodium-induced colitis by deteriorating the gut barrier function and microbial community in mice.
Qin M, Lei H, Song Y, Wu M, Chen C, Cao Z, Zhang C, Du R, Zhang C, Wang X, Zhang L
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2023 Aug;178:113908
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2023 Aug;178:113908
microRNA-651-5p affects the proliferation, migration, and invasion of lung cancer cells by regulating Calmodulin 2 expression.
Lang Y, Kong X, Liu B, Jin X, Chen L, Xu S
The clinical respiratory journal 2023 Aug;17(8):754-763
The clinical respiratory journal 2023 Aug;17(8):754-763
PAG neuronal NMDARs activation mediated morphine-induced hyperalgesia by HMGB1-TLR4 dependent microglial inflammation.
Mo J, Lu Z, Peng J, Li XP, Lan L, Wang H, Peng Y
Journal of psychiatric research 2023 Aug;164:150-161
Journal of psychiatric research 2023 Aug;164:150-161
Sanghuangporus vaninii ethanol extract alleviates hyperuricemic renal injury by regulating the uric acid transporters and inhibiting HK-2 apoptosis.
Hua L, Zhang S, Yang J, Zhou X, Shi S
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Aug;164:114970
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Aug;164:114970
Hepatoprotective effect of Typhaneoside on non-alcoholic fatty liver disease via farnesoid X receptor in vivo and in vitro.
Zheng Y, Zhao J, Miao D, Xu T, Wang L, Liu C, Gao Y, Yu L, Shen C
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Aug;164:114957
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Aug;164:114957
The Chinese herbal medicine Fufang Zhenzhu Tiaozhi ameliorates diabetic cardiomyopathy by regulating cardiac abnormal lipid metabolism and mitochondrial dynamics in diabetic mice.
Yan M, Liu S, Zeng W, Guo Q, Mei Y, Shao X, Su L, Liu Z, Zhang Y, Wang L, Diao H, Rong X, Guo J
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Aug;164:114919
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Aug;164:114919
Fluorofenidone protects against acute liver failure in mice by regulating MKK4/JNK pathway.
Gu L, He X, Zhang Y, Li S, Tang J, Ma R, Yang X, Huang H, Peng Y, Xie Y, Peng Z, Meng J, Hu G, Tao L, Liu X, Yang H
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Aug;164:114844
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Aug;164:114844
CACYBP knockdown inhibits progression of prostate cancer via p53.
Li Q, Liu Z, Ma L, Yin W, Zhang K
Journal of cancer research and clinical oncology 2023 Aug;149(9):5761-5772
Journal of cancer research and clinical oncology 2023 Aug;149(9):5761-5772
Split-Cas9-based targeted gene editing and nanobody-mediated proteolysis-targeting chimeras optogenetically coordinated regulation of Survivin to control the fate of cancer cells.
Deng C, Li S, Liu Y, Bao W, Xu C, Zheng W, Wang M, Ma X
Clinical and translational medicine 2023 Aug;13(8):e1382
Clinical and translational medicine 2023 Aug;13(8):e1382
MIF promotes Th17 cell differentiation in Hashimoto's thyroiditis by binding HVEM and activating NF-κB signaling pathway.
Liu Z, Li Z, Yan G, Lin C, Luo Y, Ye Y, Zeng X, Yao J
International immunopharmacology 2023 Aug;121:110494
International immunopharmacology 2023 Aug;121:110494
Immunosensitivity mediated by downregulated AKT1-SKP2 induces anti-PD-1-associated thyroid immune injury.
Wu Y, Li J, Yang X, Hou B, Qiao H
International immunopharmacology 2023 Aug;121:110452
International immunopharmacology 2023 Aug;121:110452
ROR1/STAT3 positive feedback loop facilitates cartilage degeneration in Osteoarthritis through activation of NF-κB signaling pathway.
Huang W, Tang H, Liu Y, Li W, Shimu AS, Li B, Zhu C
International immunopharmacology 2023 Aug;121:110433
International immunopharmacology 2023 Aug;121:110433
TSLP/TSLPR promotes renal fibrosis by activating STAT3 in renal fibroblasts.
Wang D, Wang F, Huang Y, Wang J, Luo H, Zhang P, Peng J, Tang G, Wang Y, Yu L, Ni D
International immunopharmacology 2023 Aug;121:110430
International immunopharmacology 2023 Aug;121:110430
The innate immune sensor STING accelerates neointima formation via NF-κB signaling pathway.
He L, Liu D, Zhou W, Han Y, Ju Y, Liu H, Chen Y, Yu J, Wang L, Wang J, He C
International immunopharmacology 2023 Aug;121:110412
International immunopharmacology 2023 Aug;121:110412
Origin of the OAS-RNase L innate immune pathway before the rise of jawed vertebrates via molecular tinkering.
Chu L, Gong Z, Wang W, Han GZ
Proceedings of the National Academy of Sciences of the United States of America 2023 Aug;120(31):e2304687120
Proceedings of the National Academy of Sciences of the United States of America 2023 Aug;120(31):e2304687120
ROS Scavenging Nanozyme Modulates Immunosuppression for Sensitized Cancer Immunotherapy.
Mo W, Liu S, Zhao X, Wei F, Li Y, Sheng X, Cao W, Ding M, Zhang W, Chen X, Meng L, Yao S, Diao W, Wei H, Guo H
Advanced healthcare materials 2023 Aug;12(21):e2300191
Advanced healthcare materials 2023 Aug;12(21):e2300191
Identification and validation of Birc5 as a novel activated cell cycle program biomarker associated with infiltration of immunosuppressive myeloid-derived suppressor cells in hepatocellular carcinoma.
Liu Y, Chen X, Luo W, Zhao Y, Nashan B, Huang L, Yuan X
Cancer medicine 2023 Aug;12(15):16370-16385
Cancer medicine 2023 Aug;12(15):16370-16385
Screening of novel serum biomarkers for gastric cancer in coastal populations using a protein microarray.
Yi Y, Nan R, Lu J, Liang D, Zhao S, Wang X, Zhang H, Chen B, Chen J, Zheng Z, You T, Chen T, Chen X, Wang W, Lin L, Chen Y, Liu S, Huang Y, Yu Y, Lu M, Li P, Huang H, Zhou G, Lin X, Wu H, Shen X, Sun W
Cancer science 2023 Aug;114(8):3396-3410
Cancer science 2023 Aug;114(8):3396-3410
WDR54 exerts oncogenic roles in T-cell acute lymphoblastic leukemia.
Li H, Zhang D, Fu Q, Wang S, Zhang X, Lin Z, Wang Z, Song J, Su Z, Xue V, Liu S, Chen Y, Zhou L, Zhao N, Lu D
Cancer science 2023 Aug;114(8):3318-3329
Cancer science 2023 Aug;114(8):3318-3329
TRIM29 acts as a potential senescence suppressor with epigenetic activation in nasopharyngeal carcinoma.
Yue C, Qian Y, Wang C, Chen J, Wang J, Wang Z, Wan X, Cao S, Zhu J, Tao Q, Yan M, Liu Q
Cancer science 2023 Aug;114(8):3176-3189
Cancer science 2023 Aug;114(8):3176-3189
Augmenter of liver regeneration promotes drug resistance of acute lymphoblastic leukemia through the alteration of mitochondrial functions and the inhibition of the mitochondrial apoptosis pathway.
Zhou J, Zhou Y, Yuan S, Li Y, Xiao W, Zhang P, Lou S, Shen Y
European journal of haematology 2023 Aug;111(2):279-292
European journal of haematology 2023 Aug;111(2):279-292
Tumor-secreted GRP78 induces M2 polarization of macrophages by promoting lipid catabolism.
Tian J, Zhang L, La X, Fan X, Li A, Wu C, An Y, Yan S, Dong X, Wu H, Li Z
Cellular signalling 2023 Aug;108:110719
Cellular signalling 2023 Aug;108:110719
A high-concentrate diet induces mitochondrial dysfunction by activating the MAPK signaling pathway in the mammary gland of dairy cows.
Meng M, Li X, Huo R, Ma N, Chang G, Shen X
Journal of dairy science 2023 Aug;106(8):5775-5787
Journal of dairy science 2023 Aug;106(8):5775-5787
Bone Marrow Mesenchymal Stem Cell-Derived Dermcidin-Containing Migrasomes enhance LC3-Associated Phagocytosis of Pulmonary Macrophages and Protect against Post-Stroke Pneumonia.
Li T, Su X, Lu P, Kang X, Hu M, Li C, Wang S, Lu D, Shen S, Huang H, Liu Y, Deng X, Cai W, Wei L, Lu Z
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Aug;10(22):e2206432
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Aug;10(22):e2206432
Structural Characterization of Zinc-Sucrose Complex and Its Ability to Promote Zinc Absorption in Caco-2 Monolayer Cells and Mice.
Li N, Wang R, Deng Z, Zhou J, Li W, Du Q, Zheng L
Journal of agricultural and food chemistry 2023 Aug 9;71(31):12094-12104
Journal of agricultural and food chemistry 2023 Aug 9;71(31):12094-12104
Tau deficiency inhibits classically activated macrophage polarization and protects against collagen-induced arthritis in mice.
Chen M, Fu W, Xu H, Liu CJ
Arthritis research & therapy 2023 Aug 9;25(1):146
Arthritis research & therapy 2023 Aug 9;25(1):146
SMAD2 inhibits pyroptosis of fibroblast-like synoviocytes and secretion of inflammatory factors via the TGF-β pathway in rheumatoid arthritis.
Mao X, Wu W, Nan Y, Sun W, Wang Y
Arthritis research & therapy 2023 Aug 9;25(1):144
Arthritis research & therapy 2023 Aug 9;25(1):144
Metformin Ameliorates Postoperative Cognitive Dysfunction through Regulation of the AMPK/SIRT1 Pathway.
Jia P, Che J, Zhang J, Li H, Zhou Q, Guo Y
Journal of integrative neuroscience 2023 Aug 9;22(5):110
Journal of integrative neuroscience 2023 Aug 9;22(5):110
The deubiquitinase EIF3H promotes hepatocellular carcinoma progression by stabilizing OGT and inhibiting ferroptosis.
Tang J, Long G, Li X, Zhou L, Zhou Y, Wu Z
Cell communication and signaling : CCS 2023 Aug 9;21(1):198
Cell communication and signaling : CCS 2023 Aug 9;21(1):198
Toxoplasma gondii Reactivation Aggravating Cardiac Function Impairment in Mice.
Xie L, Xing Y, Yang J, Liu M, Cai Y
Pathogens (Basel, Switzerland) 2023 Aug 9;12(8)
Pathogens (Basel, Switzerland) 2023 Aug 9;12(8)
Systemic Pharmacology Reveals the Potential Targets and Signaling Mechanisms in the Adjuvant Treatment of Brucellosis with Traditional Chinese Medicine.
Zhao T, Zhang Y, Liu L, Deng X, Guo J, Cao S, Zhu D, Xu J, Nikolaevna UV, Maratbek S, Wang Z, Sun Z, Gu X, Zhang H
ACS omega 2023 Aug 8;8(31):28797-28812
ACS omega 2023 Aug 8;8(31):28797-28812
CircUSP48 promotes malignant behavior by regulating CYR61 via miR-365 in osteosarcoma.
Chen S, Xu Y, Yang B
Functional & integrative genomics 2023 Aug 8;23(3):270
Functional & integrative genomics 2023 Aug 8;23(3):270
YY1 regulates the proliferation and invasion of triple-negative breast cancer via activating PLAUR.
Zhang C, Chen S, Wang W, Gao Y
Functional & integrative genomics 2023 Aug 8;23(3):269
Functional & integrative genomics 2023 Aug 8;23(3):269
Identification of a novel bile marker clusterin and a public online prediction platform based on deep learning for cholangiocarcinoma.
Gao L, Lin Y, Yue P, Li S, Zhang Y, Mi N, Bai M, Fu W, Xia Z, Jiang N, Cao J, Yang M, Ma Y, Zhang F, Zhang C, Leung JW, He S, Yuan J, Meng W, Li X
BMC medicine 2023 Aug 8;21(1):294
BMC medicine 2023 Aug 8;21(1):294
Mitochondrial carrier 1 (MTCH1) governs ferroptosis by triggering the FoxO1-GPX4 axis-mediated retrograde signaling in cervical cancer cells.
Wang X, Ji Y, Qi J, Zhou S, Wan S, Fan C, Gu Z, An P, Luo Y, Luo J
Cell death & disease 2023 Aug 8;14(8):508
Cell death & disease 2023 Aug 8;14(8):508
Intermittent dietary methionine deprivation facilitates tumoral ferroptosis and synergizes with checkpoint blockade.
Xue Y, Lu F, Chang Z, Li J, Gao Y, Zhou J, Luo Y, Lai Y, Cao S, Li X, Zhou Y, Li Y, Tan Z, Cheng X, Li X, Chen J, Wang W
Nature communications 2023 Aug 8;14(1):4758
Nature communications 2023 Aug 8;14(1):4758
FERM domain containing kindlin 1 knockdown attenuates inflammation induced by intracerebral hemorrhage in rats via NLR family pyrin domain containing 3/nuclear factor kappa B pathway.
Wei J, Yin J, Cui Y, Wang K, Hong M, Cui J
Experimental animals 2023 Aug 7;72(3):324-335
Experimental animals 2023 Aug 7;72(3):324-335
Ultrafast single-molecule imaging reveals focal adhesion nano-architecture and molecular dynamics.
Fujiwara TK, Tsunoyama TA, Takeuchi S, Kalay Z, Nagai Y, Kalkbrenner T, Nemoto YL, Chen LH, Shibata ACE, Iwasawa K, Ritchie KP, Suzuki KGN, Kusumi A
The Journal of cell biology 2023 Aug 7;222(8)
The Journal of cell biology 2023 Aug 7;222(8)
Transcriptional variation in Babesia gibsoni (Wuhan isolate) between in vivo and in vitro cultures in blood stage.
Han Z, Zheng Y, Shi Y, Chen F, Wu C, Wang L, Lu S, Li D, Guan X, He L, Zhao J
Parasites & vectors 2023 Aug 7;16(1):268
Parasites & vectors 2023 Aug 7;16(1):268
ABCD1 Transporter Deficiency Results in Altered Cholesterol Homeostasis.
Buda A, Forss-Petter S, Hua R, Jaspers Y, Lassnig M, Waidhofer-Söllner P, Kemp S, Kim P, Weinhofer I, Berger J
Biomolecules 2023 Aug 31;13(9)
Biomolecules 2023 Aug 31;13(9)
Inhibition of Trichinella spiralis Membrane-Associated Progesterone Receptor (MAPR) Results in a Reduction in Worm Burden.
Aleem MT, Wen Z, Yu Z, Chen C, Lu M, Xu L, Song X, Li X, Yan R
Vaccines 2023 Aug 31;11(9)
Vaccines 2023 Aug 31;11(9)
Inhibitory effect of Dendrobium officinale polysaccharide on oxidative damage of glial cells in aging mice by regulating gut microbiota.
Xu L, Zeng X, Liu Y, Wu Z, Zheng X, Zhang X
International journal of biological macromolecules 2023 Aug 30;247:125787
International journal of biological macromolecules 2023 Aug 30;247:125787
ADRM1/RPN13 attenuates cartilage extracellular matrix degradation via enhancing UCH37-mediated ALK5 deubiquitination.
Zhu M, Cao Z, Mo F, Shi S, Hu J, Xu Q, Quan K, Liang J, Li W, Hong X, Zhang B, Liu X, Dai M
International journal of biological macromolecules 2023 Aug 30;247:125670
International journal of biological macromolecules 2023 Aug 30;247:125670
CAR-T cells targeting CD38 and LMP1 exhibit robust antitumour activity against NK/T cell lymphoma.
Li H, Song W, Wu J, Shi Z, Gao Y, Li J, Han L, Zhang J, Li Z, Li Y, Zhang M
BMC medicine 2023 Aug 30;21(1):330
BMC medicine 2023 Aug 30;21(1):330
Hepatocyte-specific Sox9 knockout ameliorates acute liver injury by suppressing SHP signaling and improving mitochondrial function.
Qin D, Wang R, Ji J, Wang D, Lu Y, Cao S, Chen Y, Wang L, Chen X, Zhang L
Cell & bioscience 2023 Aug 30;13(1):159
Cell & bioscience 2023 Aug 30;13(1):159
Effect of Gut Microbiota on the Pharmacokinetics of Nifedipine in Spontaneously Hypertensive Rats.
Zhou R, Yang H, Zhu P, Liu Y, Zhang Y, Zhang W, Zhou H, Li X, Li Q
Pharmaceutics 2023 Aug 3;15(8)
Pharmaceutics 2023 Aug 3;15(8)
Ypel5 regulates liver development and function in zebrafish.
Deng Y, Han X, Chen H, Zhao C, Chen Y, Zhou J, de The H, Zhu J, Yuan H
Journal of molecular cell biology 2023 Aug 3;15(3)
Journal of molecular cell biology 2023 Aug 3;15(3)
Mis-splicing Drives Loss of Function of p53(E224D) Point Mutation.
Lock IC, Leisenring NH, Floyd W, Xu ES, Luo L, Ma Y, Mansell EC, Cardona DM, Lee CL, Kirsch DG
bioRxiv : the preprint server for biology 2023 Aug 3;
bioRxiv : the preprint server for biology 2023 Aug 3;
Cell-type-specific regulation of APOE and CLU levels in human neurons by the Alzheimer's disease risk gene SORL1.
Lee H, Aylward AJ, Pearse RV 2nd, Lish AM, Hsieh YC, Augur ZM, Benoit CR, Chou V, Knupp A, Pan C, Goberdhan S, Duong DM, Seyfried NT, Bennett DA, Taga MF, Huynh K, Arnold M, Meikle PJ, De Jager PL, Menon V, Young JE, Young-Pearse TL
Cell reports 2023 Aug 29;42(8):112994
Cell reports 2023 Aug 29;42(8):112994
The miR-17∼92 miRNAs promote plasma cell differentiation by suppressing SOCS3-mediated NIK degradation.
Xie J, Du Y, Liu D, Wu J, Yang K, He X, Zhao J, Hong P, Liao K, Zhang H, Hong Y, Teijaro JR, Kang SG, Xiao C, Liu WH
Cell reports 2023 Aug 29;42(8):112968
Cell reports 2023 Aug 29;42(8):112968
NFYC-37 promotes tumor growth by activating the mevalonate pathway in bladder cancer.
Liu Z, Zheng X, Chen J, Zheng L, Ma Z, Chen L, Deng M, Tang H, Zhou L, Kang T, Wu Y, Liu Z
Cell reports 2023 Aug 29;42(8):112963
Cell reports 2023 Aug 29;42(8):112963
MOF-mediated acetylation of SIRT6 disrupts SIRT6-FOXA2 interaction and represses SIRT6 tumor-suppressive function by upregulating ZEB2 in NSCLC.
Zhao K, Zheng M, Su Z, Ghosh S, Zhang C, Zhong W, Ho JWK, Jin G, Zhou Z
Cell reports 2023 Aug 29;42(8):112939
Cell reports 2023 Aug 29;42(8):112939
Dendritic distribution of autophagosomes underlies pathway-selective induction of LTD.
Keary KM 3rd, Gu QH, Chen J, Li Z
Cell reports 2023 Aug 29;42(8):112898
Cell reports 2023 Aug 29;42(8):112898
Sox10 escalates vascular inflammation by mediating vascular smooth muscle cell transdifferentiation and pyroptosis in neointimal hyperplasia.
Xu X, Zhang DD, Kong P, Gao YK, Huang XF, Song Y, Zhang WD, Guo RJ, Li CL, Chen BW, Sun Y, Zhao YB, Jia FY, Wang X, Zhang F, Han M
Cell reports 2023 Aug 29;42(8):112869
Cell reports 2023 Aug 29;42(8):112869
POGZ suppresses 2C transcriptional program and retrotransposable elements.
Sun X, Zhang T, Tong B, Cheng L, Jiang W, Sun Y
Cell reports 2023 Aug 29;42(8):112867
Cell reports 2023 Aug 29;42(8):112867
A p53/LINC00324 positive feedback loop suppresses tumor growth by counteracting SET-mediated transcriptional repression.
Zhang L, Zhang J, Xuan X, Wu D, Yu J, Wang P, Yang X, Zhang J, Gan W, He M, Liu XM, Zhou J, Wang D, Gu W, Li D
Cell reports 2023 Aug 29;42(8):112833
Cell reports 2023 Aug 29;42(8):112833
SP1-Induced Upregulation of LncRNA AFAP1-AS1 Promotes Tumor Progression in Triple-Negative Breast Cancer by Regulating mTOR Pathway.
Li F, Xian D, Huang J, Nie L, Xie T, Sun Q, Zhang X, Zhou Y
International journal of molecular sciences 2023 Aug 29;24(17)
International journal of molecular sciences 2023 Aug 29;24(17)
Stem of Sorbus commixta Hedl. Extract Inhibits Cartilage Degradation and Arthritic Pain in Experimental Model via Anti-Inflammatory Activity.
Jo HG, Baek CY, Kim D, Lee D, Song HS
Nutrients 2023 Aug 29;15(17)
Nutrients 2023 Aug 29;15(17)
Measuring tryptophan dynamics using fast scan cyclic voltammetry at carbon fiber microelectrodes with improved sensitivity and selectivity.
Schapira I, O'Neill MR, Russo-Savage L, Narla T, Laprade KA, Stafford JM, Ou Y
RSC advances 2023 Aug 29;13(37):26203-26212
RSC advances 2023 Aug 29;13(37):26203-26212
Riluzole Suppresses Growth and Enhances Response to Endocrine Therapy in ER+ Breast Cancer.
Olukoya AO, Stires H, Bahnassy S, Persaud S, Guerra Y, Ranjit S, Ma S, Cruz MI, Benitez C, Rozeboom AM, Ceuleers H, Berry DL, Jacobsen BM, Raj GV, Riggins RB
Journal of the Endocrine Society 2023 Aug 28;7(10):bvad117
Journal of the Endocrine Society 2023 Aug 28;7(10):bvad117
Disulfiram/Copper Induce Ferroptosis in Triple-Negative Breast Cancer Cell Line MDA-MB-231.
Chu M, An X, Fu C, Yu H, Zhang D, Li Q, Man X, Dai X, Li Z
Frontiers in bioscience (Landmark edition) 2023 Aug 28;28(8):186
Frontiers in bioscience (Landmark edition) 2023 Aug 28;28(8):186
Rutaecarpine Ameliorates Murine N-Methyl-N'-Nitro-N-Nitrosoguanidine-Induced Chronic Atrophic Gastritis by Sonic Hedgehog Pathway.
He Y, Liu HH, Zhou XL, He TT, Zhang AZ, Wang X, Wei SZ, Li HT, Chen LS, Chang L, Zhao YL, Jing MY
Molecules (Basel, Switzerland) 2023 Aug 28;28(17)
Molecules (Basel, Switzerland) 2023 Aug 28;28(17)
LncRNA GAS5-hnRNPK axis inhibited ovarian cancer progression via inhibition of AKT signaling in ovarian cancer cells.
Zhang T, Leng Y, Duan M, Li Z, Ma Y, Huang C, Shi Q, Wang Y, Wang C, Liu D, Zhao X, Cheng S, Liu A, Zhou Y, Liu J, Pan Z, Zhang H, Shen L, Zhao H
Discover oncology 2023 Aug 28;14(1):157
Discover oncology 2023 Aug 28;14(1):157
EZH2 inhibitor Tazemetostat synergizes with JQ-1 in esophageal cancer by inhibiting c-Myc signaling pathway.
Ding N, You A, Zhao S, Yang H, Lai C, Ye F
Medical oncology (Northwood, London, England) 2023 Aug 27;40(10):281
Medical oncology (Northwood, London, England) 2023 Aug 27;40(10):281
SPDEF enhances cancer stem cell-like properties and tumorigenesis through directly promoting GALNT7 transcription in luminal breast cancer.
Li J, Wan X, Xie D, Yuan H, Pei Q, Luo Y, Chen Y, Xian J, Ye T
Cell death & disease 2023 Aug 26;14(8):569
Cell death & disease 2023 Aug 26;14(8):569
The DDUP protein encoded by the DNA damage-induced CTBP1-DT lncRNA confers cisplatin resistance in ovarian cancer.
Ren L, Qing X, Wei J, Mo H, Liu Y, Zhi Y, Lu W, Zheng M, Zhang W, Chen Y, Zhang Y, Pan T, Zhong Q, Li R, Zhang X, Ruan X, Yu R, Li J
Cell death & disease 2023 Aug 26;14(8):568
Cell death & disease 2023 Aug 26;14(8):568
Hyperelatolides A-D, Antineuroinflammatory Constituents with Unusual Carbon Skeletons from Hypericum elatoides.
Xie JY, Wang ZX, Liu WY, Liu HW, Li D, Sang YF, Yang Z, Gao JM, Yan XT
Journal of natural products 2023 Aug 25;86(8):1910-1918
Journal of natural products 2023 Aug 25;86(8):1910-1918
Structural basis for specific DNA sequence motif recognition by the TFAP2 transcription factors.
Liu K, Xiao Y, Gan L, Li W, Zhang J, Min J
Nucleic acids research 2023 Aug 25;51(15):8270-8282
Nucleic acids research 2023 Aug 25;51(15):8270-8282
Liquiritigenin Confers Liver Protection by Enhancing NRF2 Signaling through Both Canonical and Non-canonical Signaling Pathways.
Shi M, Zhang J, Li M, Zhao Y, Guo Y, Xu J, Liu R, Li Z, Ren D, Liu P
Journal of medicinal chemistry 2023 Aug 24;66(16):11324-11334
Journal of medicinal chemistry 2023 Aug 24;66(16):11324-11334
A20 promotes colorectal cancer immune evasion by upregulating STC1 expression to block "eat-me" signal.
Luo M, Wang X, Wu S, Yang C, Su Q, Huang L, Fu K, An S, Xie F, To KKW, Wang F, Fu L
Signal transduction and targeted therapy 2023 Aug 23;8(1):312
Signal transduction and targeted therapy 2023 Aug 23;8(1):312
Unraveling Vulnerabilities in Endocrine Therapy-Resistant HER2+/ER+ Breast Cancer.
Bahnassy S, Stires H, Jin L, Tam S, Mobin D, Balachandran M, Podar M, McCoy MD, Beckman RA, Riggins RB
bioRxiv : the preprint server for biology 2023 Aug 22;
bioRxiv : the preprint server for biology 2023 Aug 22;
HtrA1 prevents and reverses α-synuclein aggregation, rendering it non-toxic and seeding incompetent.
Chen S, Puri A, Bell B, Fritsche J, Palacios H, Balch M, Sprunger M, Howard M, Patterson J, Patti G, Davis A, Jackrel M
Research square 2023 Aug 22;
Research square 2023 Aug 22;
GABA(B) Receptor Activation Attenuates Neuronal Pyroptosis in Post-cardiac Arrest Brain Injury.
Sun Y, Li J, Wu H, Zhao Z, Cong T, Li L, Zhang X, Yin S, Xiao Z
Neuroscience 2023 Aug 21;526:97-106
Neuroscience 2023 Aug 21;526:97-106
Oxidative Stress-mediated Sprouty-related Protein with an EVH1 Domain 1 Down-regulation Contributes to Resisting Oxidative Injury in Microglia.
Wei L, Li X, Wei Q, Chen L, Xu L, Zhou P
Neuroscience 2023 Aug 21;526:13-20
Neuroscience 2023 Aug 21;526:13-20
Injectable photocrosslinking spherical hydrogel-encapsulated targeting peptide-modified engineered exosomes for osteoarthritis therapy.
Wan J, He Z, Peng R, Wu X, Zhu Z, Cui J, Hao X, Chen A, Zhang J, Cheng P
Journal of nanobiotechnology 2023 Aug 21;21(1):284
Journal of nanobiotechnology 2023 Aug 21;21(1):284
Knockdown of SETD2 promotes erastin-induced ferroptosis in ccRCC.
Xue W, Jian W, Meng Y, Wang T, Cai L, Yu Y, Yu Y, Xia Z, Zhang C
Cell death & disease 2023 Aug 21;14(8):539
Cell death & disease 2023 Aug 21;14(8):539
USP33 promotes nonalcoholic fatty acid disease-associated fibrosis in gerbils via the c-myc signaling.
Ke X, Hu H, Peng Q, Ying H, Chu X
Biochemical and biophysical research communications 2023 Aug 20;669:68-76
Biochemical and biophysical research communications 2023 Aug 20;669:68-76
[Guizhi Fuling Capsule inhibits migration and induces apoptosis of human ovarian cancer cells by regulating the NF-κB signaling pathway].
Guo X, Chen L, Lü Q, DU R, Luo Q, Zhang Y, Bian H, Han L
Nan fang yi ke da xue xue bao = Journal of Southern Medical University 2023 Aug 20;43(8):1315-1321
Nan fang yi ke da xue xue bao = Journal of Southern Medical University 2023 Aug 20;43(8):1315-1321
[Dihydromyricetin alleviates pyroptosis and necroptosis in mice with MPTP-induced chronic Parkinson's disease by inducing autophagy].
Zhang M, Zhang Y, Niu M, Zhu Y, Tong S, Kou X
Nan fang yi ke da xue xue bao = Journal of Southern Medical University 2023 Aug 20;43(8):1268-1278
Nan fang yi ke da xue xue bao = Journal of Southern Medical University 2023 Aug 20;43(8):1268-1278
B7-H3 confers stemness characteristics to gastric cancer cells by promoting glutathione metabolism through AKT/pAKT/Nrf2 pathway.
Xia L, Chen Y, Li J, Wang J, Shen K, Zhao A, Jin H, Zhang G, Xi Q, Xia S, Shi T, Li R
Chinese medical journal 2023 Aug 20;136(16):1977-1989
Chinese medical journal 2023 Aug 20;136(16):1977-1989
UCP1 alleviates renal interstitial fibrosis progression through oxidative stress pathway mediated by SIRT3 protein stability.
Xiong W, Xiong Z, Song A, Lei C, Ye C, Su H, Zhang C
Journal of translational medicine 2023 Aug 2;21(1):521
Journal of translational medicine 2023 Aug 2;21(1):521
Role of dendritic cells in MYD88-mediated immune recognition and osteoinduction initiated by the implantation of biomaterials.
Zhao Z, Zhao Q, Chen H, Chen F, Wang F, Tang H, Xia H, Zhou Y, Sun Y
International journal of oral science 2023 Aug 2;15(1):31
International journal of oral science 2023 Aug 2;15(1):31
BIK1 protein homeostasis is maintained by the interplay of different ubiquitin ligases in immune signaling.
Bai J, Zhou Y, Sun J, Chen K, Han Y, Wang R, Zou Y, Du M, Lu D
Nature communications 2023 Aug 2;14(1):4624
Nature communications 2023 Aug 2;14(1):4624
FOXA1 O-GlcNAcylation-mediated transcriptional switch governs metastasis capacity in breast cancer.
Liu Y, Yu K, Kong X, Zhang K, Wang L, Zhang N, Chen Q, Niu M, Li W, Zhong X, Wu S, Zhang J, Liu Y
Science advances 2023 Aug 18;9(33):eadg7112
Science advances 2023 Aug 18;9(33):eadg7112
Increased NMDARs in neurons and glutamine synthetase in astrocytes underlying autistic-like behaviors of Gabrb1(-/-) mice.
Wang J, Gao Y, Xiao L, Lin Y, Huang L, Chen J, Liang G, Li W, Yi W, Lao J, Zhang B, Gao TM, Zhong M, Yang X
iScience 2023 Aug 18;26(8):107476
iScience 2023 Aug 18;26(8):107476
STING-IRG1 inhibits liver metastasis of colorectal cancer by regulating the polarization of tumor-associated macrophages.
Liu Y, Sun Q, Zhang C, Ding M, Wang C, Zheng Q, Ma Z, Xu H, Zhou G, Wang X, Cheng Z, Xia H
iScience 2023 Aug 18;26(8):107376
iScience 2023 Aug 18;26(8):107376
Magneto-mechanical stimulation modulates osteocyte fate via the ECM-integrin-CSK axis and wnt pathway.
Zhang B, Li X, Zhou X, Lou C, Wang S, Lv H, Zhang G, Fang Y, Yin D, Shang P
iScience 2023 Aug 18;26(8):107365
iScience 2023 Aug 18;26(8):107365
PAK1 contributes to cerebral ischemia/reperfusion injury by regulating the blood-brain barrier integrity.
Huang M, Zhang J, Li M, Cao H, Zhu Q, Yang D
iScience 2023 Aug 18;26(8):107333
iScience 2023 Aug 18;26(8):107333
Advanced oxidation protein products induce Paneth cells defects by endoplasmic reticulum stress in Crohn's disease.
Shi J, Wang W, Sun S, Xu X, Fei J, Zhou Q, Qin C, Ou S, Wu F, Wu FT, Xu T, Bai L, Xie F
iScience 2023 Aug 18;26(8):107312
iScience 2023 Aug 18;26(8):107312
O-GlcNAcylation of Raptor transduces glucose signals to mTORC1.
Xu C, Pan X, Wang D, Guan Y, Yang W, Chen X, Liu Y
Molecular cell 2023 Aug 17;83(16):3027-3040.e11
Molecular cell 2023 Aug 17;83(16):3027-3040.e11
Comprehensive characterization of pyroptosis phenotypes with distinct tumor immune profiles in gastric cancer to aid immunotherapy.
Huang K, Lin Y, Qiu G, Wang S, Feng L, Zheng Z, Gao Y, Fan X, Zheng W, Zhuang J, Luo F, Feng S
Aging 2023 Aug 17;15(16):8113-8136
Aging 2023 Aug 17;15(16):8113-8136
N-Linked Glycosylation and Expression of Duck Plague Virus pUL10 Promoted by pUL49.5.
Li C, Wang M, Cheng A, Wu Y, Tian B, Yang Q, Gao Q, Sun D, Zhang S, Ou X, He Y, Huang J, Zhao X, Chen S, Zhu D, Liu M, Jia R
Microbiology spectrum 2023 Aug 17;11(4):e0162523
Microbiology spectrum 2023 Aug 17;11(4):e0162523
Piscine Vitamin D Receptors Vdra/Vdrb in the Absence of Vitamin D Are Utilized by Grass Carp Reovirus for Promoting Viral Replication.
Song YJ, Zhang J, Xiao J, Feng H, Xu Z, Nie P, Chang MX
Microbiology spectrum 2023 Aug 17;11(4):e0128723
Microbiology spectrum 2023 Aug 17;11(4):e0128723
A Recombinant Duck Plague Virus Containing the ICP27 Deletion Marker Provides Robust Protection in Ducks.
Wu Y, Liu L, Zhang M, Zhan H, Wang C, Wang M, Chen S, Jia R, Yang Q, Zhu D, Liu M, Zhao X, Zhang S, Huang J, Ou X, Mao S, Gao Q, Sun D, Tian B, Cheng A
Microbiology spectrum 2023 Aug 17;11(4):e0098323
Microbiology spectrum 2023 Aug 17;11(4):e0098323
ATP6V1F is a novel prognostic biomarker and potential immunotherapy target for hepatocellular carcinoma.
Hu X, Li D, Zhu H, Yu T, Xiong X, Xu X
BMC medical genomics 2023 Aug 16;16(1):188
BMC medical genomics 2023 Aug 16;16(1):188
Integrin β(3) directly inhibits the Gα(13)-p115RhoGEF interaction to regulate G protein signaling and platelet exocytosis.
Zhang Y, Zhao X, Shen B, Bai Y, Chang C, Stojanovic A, Wang C, Mack A, Deng G, Skidgel RA, Cheng N, Du X
Nature communications 2023 Aug 16;14(1):4966
Nature communications 2023 Aug 16;14(1):4966
Hedyotis diffusa-Sculellaria barbata (HD-SB) suppresses the progression of colorectal cancer cells via the hsa_circ_0039933/hsa-miR-204-5p/wnt11 axis.
Zhu D, Yuan S, Chen C
Scientific reports 2023 Aug 16;13(1):13331
Scientific reports 2023 Aug 16;13(1):13331
Berberine modulates gut microbiota to attenuate cerebral ferroptosis induced by ischemia-reperfusion in mice.
Wang X, Zhang J, Wang S, Song Z, Sun H, Wu F, Lin X, Jin K, Jin X, Wang W, Lin Q, Wang F
European journal of pharmacology 2023 Aug 15;953:175782
European journal of pharmacology 2023 Aug 15;953:175782
Dihydromyricetin attenuates cisplatin-induced acute kidney injury by reducing oxidative stress, inflammation and ferroptosis.
Xu Z, Zhang M, Wang W, Zhou S, Yu M, Qiu X, Jiang S, Wang X, Tang C, Li S, Wang CH, Zhu R, Peng WX, Zhao L, Fu X, Patzak A, Persson PB, Zhao L, Mao J, Shu Q, Lai EY, Zhang G
Toxicology and applied pharmacology 2023 Aug 15;473:116595
Toxicology and applied pharmacology 2023 Aug 15;473:116595
Analyzing roles of small nucleolar RNA host gene 25 from clinical, molecular target and tumor formation in prostate cancer.
Liu Z, Ke S, Wang Q, Gu X, Zhai G, Shao H, He M, Guo J
Experimental cell research 2023 Aug 15;429(2):113686
Experimental cell research 2023 Aug 15;429(2):113686
Methionine orchestrates the metabolism vulnerability in cisplatin resistant bladder cancer microenvironment.
Yang C, Ou Y, Zhou Q, Liang Y, Li W, Chen Y, Chen W, Wu S, Chen Y, Dai X, Chen X, Chen T, Jin S, Liu Y, Zhang L, Liu S, Hu Y, Zou L, Mao S, Jiang H
Cell death & disease 2023 Aug 15;14(8):525
Cell death & disease 2023 Aug 15;14(8):525
The RNA-binding protein KSRP aggravates malignant progression of clear cell renal cell carcinoma through transcriptional inhibition and post-transcriptional destabilization of the NEDD4L ubiquitin ligase.
Yang YC, Lin YW, Lee WJ, Lai FR, Ho KH, Chu CY, Hua KT, Chen JQ, Tung MC, Hsiao M, Wen YC, Chien MH
Journal of biomedical science 2023 Aug 14;30(1):68
Journal of biomedical science 2023 Aug 14;30(1):68
Systemic Mutation of Ncf1 Ameliorates Obstruction-Induced Renal Fibrosis While Macrophage-Rescued NCF1 Further Alleviates Renal Fibrosis.
Huang F, Ren X, Yuan B, Yang W, Xu L, Zhang J, Zhang H, Geng M, Li X, Zhang F, Xu J, Zhu W, Ren S, Meng L, Lu S
Antioxidants & redox signaling 2023 Aug 14;
Antioxidants & redox signaling 2023 Aug 14;
Targeted Protein Degradation through Recruitment of the CUL4A Complex Adaptor Protein DDB1.
Meyers M, Cismoski S, Panidapu A, Chie-Leon B, Nomura DK
bioRxiv : the preprint server for biology 2023 Aug 12;
bioRxiv : the preprint server for biology 2023 Aug 12;
Taraxasterol suppresses the proliferation and tumor growth of androgen-independent prostate cancer cells through the FGFR2-PI3K/AKT signaling pathway.
Yang J, Xin C, Yin G, Li J
Scientific reports 2023 Aug 11;13(1):13072
Scientific reports 2023 Aug 11;13(1):13072
Identification of Selective ATP-Competitive CMG Helicase Inhibitors for Cancer Intervention that Disrupt CMG-Replisome Function.
Xiang S, Luo X, Welch D, Reed DR, Alexandrow MG
Research square 2023 Aug 11;
Research square 2023 Aug 11;
Simiao San alleviates hyperuricemia and kidney inflammation by inhibiting NLRP3 inflammasome and JAK2/STAT3 signaling in hyperuricemia mice.
Zhang Y, Wang S, Dai X, Liu T, Liu Y, Shi H, Yin J, Xu T, Zhang Y, Zhao D, Sukhorukov V, Orekhov AN, Gao S, Wang L, Zhang D
Journal of ethnopharmacology 2023 Aug 10;312:116530
Journal of ethnopharmacology 2023 Aug 10;312:116530
Loganin alleviated cognitive impairment in 3×Tg-AD mice through promoting mitophagy mediated by optineurin.
Zhou Y, Luo D, Shi J, Yang X, Xu W, Gao W, Guo Y, Zhao Q, Xie X, He Y, Du G, Pang X
Journal of ethnopharmacology 2023 Aug 10;312:116455
Journal of ethnopharmacology 2023 Aug 10;312:116455
Interaction of Bmal1 and eIF2α/ATF4 pathway was involved in Shuxie compound alleviation of circadian rhythm disturbance-induced hepatic endoplasmic reticulum stress.
Zhang M, Wu W, Huang C, Cai T, Wang M, Zhao N, Liu S, Yang S
Journal of ethnopharmacology 2023 Aug 10;312:116446
Journal of ethnopharmacology 2023 Aug 10;312:116446
A novel mechanism regulating pyroptosis-induced fibrosis in endometriosis via lnc-MALAT1/miR-141-3p/NLRP3 pathway†.
Xu Y, Liu H, Xiong W, Peng Y, Li X, Long X, Jin J, Liang J, Weng R, Liu J, Zhang L, Liu Y
Biology of reproduction 2023 Aug 10;109(2):156-171
Biology of reproduction 2023 Aug 10;109(2):156-171
Bellidifolin ameliorates isoprenaline-induced cardiac hypertrophy by the Nox4/ROS signalling pathway through inhibiting BRD4.
Zhou D, Liu W, Zhang J, Dong Y, Wu J, Zhang Y, Dai C, Zhang T, Yang G, Zhang Y, Li A
Cell death discovery 2023 Aug 1;9(1):279
Cell death discovery 2023 Aug 1;9(1):279
PRMT4 Facilitates White Adipose Tissue Browning and Thermogenesis by Methylating PPARγ.
Zhong Y, Wang Y, Li X, Qin H, Yan S, Rao C, Fan D, Liu D, Deng F, Miao Y, Yang L, Huang K
Diabetes 2023 Aug 1;72(8):1095-1111
Diabetes 2023 Aug 1;72(8):1095-1111
SUPPLEMENTATION WITH NICOTINAMIDE RIBOSIDE ATTENUATES T CELL EXHAUSTION AND IMPROVES SURVIVAL IN SEPSIS.
Zhao GJ, Yang XY, Zhang C, Dong W, Dong FB, Zhang J, Chen XY, Yao RQ, Xiao Z, Chen LW, Yao YM, Lu ZQ
Shock (Augusta, Ga.) 2023 Aug 1;60(2):238-247
Shock (Augusta, Ga.) 2023 Aug 1;60(2):238-247
Dibutyl phthalate induces epithelial-mesenchymal transition of renal tubular epithelial cells via the Ang II/AMPKα2/Cx43 signaling pathway.
Zhiwen X, Yongqing Z, Wenlan S, Shan H, Bangmin H, Juntao J, Yingjian Z, Yifeng J
Toxicology 2023 Aug 1;494:153584
Toxicology 2023 Aug 1;494:153584
Mucin2 regulated by Ho1/p38/IL-10 axis plays a protective role in polystyrene nanoplastics-mediated intestinal toxicity.
Cui M, He Q, Wang Z, Yu Y, Gao H, Liu Z, Peng H, Wang H, Zhang X, Li D, Chen L, Xing X, Xiao Y, Chen W, Wang Q
Environmental pollution (Barking, Essex : 1987) 2023 Aug 1;330:121808
Environmental pollution (Barking, Essex : 1987) 2023 Aug 1;330:121808
miR-342-5p promotes vascular smooth muscle cell phenotypic transition through a negative-feedback regulation of Notch signaling via targeting FOXO3.
Wen T, Duan Y, Gao D, Zhang X, Zhang X, Liang L, Yang Z, Zhang P, Zhang J, Sun J, Feng Y, Zheng Q, Han H, Yan X
Life sciences 2023 Aug 1;326:121828
Life sciences 2023 Aug 1;326:121828
Inhibition of glycolysis prevents behavioural changes in mice with MK801-induced SCZ model by alleviating lactate accumulation and lactylation.
Xie J, Hong S, Zhang X, Li Y, Xie R
Brain research 2023 Aug 1;1812:148409
Brain research 2023 Aug 1;1812:148409
PARP16-Mediated Stabilization of Amyloid Precursor Protein mRNA Exacerbates Alzheimer's Disease Pathogenesis.
Wang J, Cheng Q, Zhang Y, Hong C, Liu J, Liu X, Chang J
Aging and disease 2023 Aug 1;14(4):1458-1471
Aging and disease 2023 Aug 1;14(4):1458-1471
Dexmedetomidine Pretreatment Protects Against Myocardial Ischemia/Reperfusion Injury by Activating STAT3 Signaling.
Chen ZR, Hong Y, Wen SH, Zhan YQ, Huang WQ
Anesthesia and analgesia 2023 Aug 1;137(2):426-439
Anesthesia and analgesia 2023 Aug 1;137(2):426-439
High-intensity interval training improves fatty infiltration in the rotator cuff through the β3 adrenergic receptor in mice.
Zhou H, Chen C, Hu H, Jiang B, Yin Y, Zhang K, Shen M, Wu S, Wang Z
Bone & joint research 2023 Aug 1;12(8):455-466
Bone & joint research 2023 Aug 1;12(8):455-466
A cell-autonomous mechanism regulates BCAA catabolism in white adipocytes and systemic metabolic balance.
Aguillard AM, Tzeng J, Ferrer I, Tam BT, Lorenzo DN
bioRxiv : the preprint server for biology 2023 Aug 1;
bioRxiv : the preprint server for biology 2023 Aug 1;
Prenatally VPA exposure is likely to cause autistic-like behavior in the rats offspring via TREM2 down-regulation to affect the microglial activation and synapse alterations.
Luo L, Chen J, Wu Q, Yuan B, Hu C, Yang T, Wei H, Li T
Environmental toxicology and pharmacology 2023 Apr;99:104090
Environmental toxicology and pharmacology 2023 Apr;99:104090
HSV-1 infection-induced herpetic neuralgia involves a CCL5/CCR5-mediated inflammation mechanism.
Wu S, Yang S, Li R, Ba X, Jiang C, Xiong D, Xiao L, Sun W
Journal of medical virology 2023 Apr;95(4):e28718
Journal of medical virology 2023 Apr;95(4):e28718
LncRNA-PEAK1 promotes neuronal apoptosis after intracerebral hemorrhage by miR-466i-5p/caspase 8 axis.
Chen JX, Zhi JW, Wang YP, Ning B
Heliyon 2023 Apr;9(4):e15091
Heliyon 2023 Apr;9(4):e15091
Thrombospondin-1 mimic peptide PKHB1 induced endoplasmic reticulum stress-mediated but CD47-independent apoptosis in non-small cell lung cancer.
Ye J, Yao Y, Zhao J, Cui L, Lu G, Wang Q, Zhang P, Zhou J
Drug development research 2023 Apr;84(2):238-252
Drug development research 2023 Apr;84(2):238-252
Oridonin ameliorates acetaminophen-induced acute liver injury through ATF4/PGC-1α pathway.
Yu D, Li J, Wang Y, Guo D, Zhang X, Chen M, Zhou Z
Drug development research 2023 Apr;84(2):211-225
Drug development research 2023 Apr;84(2):211-225
SARS-CoV-2 restructures host chromatin architecture.
Wang R, Lee JH, Kim J, Xiong F, Hasani LA, Shi Y, Simpson EN, Zhu X, Chen YT, Shivshankar P, Krakowiak J, Wang Y, Gilbert DM, Yuan X, Eltzschig HK, Li W
Nature microbiology 2023 Apr;8(4):679-694
Nature microbiology 2023 Apr;8(4):679-694
LINC00115 regulates lung adenocarcinoma progression via sponging miR-154-3p to modulate Sp3 expression.
Sun K, Lu T, Hu C, Li Z, Zhu J, Zhang L, Shao X, Chen W
Molecular and cellular probes 2023 Apr;68:101909
Molecular and cellular probes 2023 Apr;68:101909
Long-Term High-Fat Diet Decreases Renal Insulin-Degrading Enzyme Expression and Function by Inhibiting the PPARγ Pathway.
Su Q, Huang J, Chen X, Wang Y, Shao M, Yan H, Chen C, Ren H, Zhang F, Ni Y, Jose PA, Zhong J, Yang J
Molecular nutrition & food research 2023 Apr;67(7):e2200589
Molecular nutrition & food research 2023 Apr;67(7):e2200589
Daurisoline suppresses esophageal squamous cell carcinoma growth in vitro and in vivo by targeting MEK1/2 kinase.
Wang D, Zhang W, Zhang X, Li M, Wu Q, Li X, Zhao L, Yuan Q, Yu Y, Lu J, Zhao J, Dong Z, Liu K, Jiang Y
Molecular carcinogenesis 2023 Apr;62(4):517-531
Molecular carcinogenesis 2023 Apr;62(4):517-531
SNORD60 promotes the tumorigenesis and progression of endometrial cancer through binding PIK3CA and regulating PI3K/AKT/mTOR signaling pathway.
Wu W, Chen X, Liu X, Bao HJ, Li QH, Xian JY, Lu BF, Zhao Y, Chen S
Molecular carcinogenesis 2023 Apr;62(4):413-426
Molecular carcinogenesis 2023 Apr;62(4):413-426
HnRNP K reduces viral gene expression by targeting cytosine-rich sequences in porcine reproductive and respiratory syndrome virus-2 genome to dampen the viral growth.
Jing H, Song Y, Li H, Duan E, Liu J, Ke W, Tao R, Li Y, Zhao P, Wang J, Cao S, Wang H, Sun Y, Zhang Y
Virology 2023 Apr;581:15-25
Virology 2023 Apr;581:15-25
Changes in N6-methyladenosine RNA methylomes of human periodontal ligament cells in response to inflammatory conditions.
Zou X, Liu C, Wu X, Yuan Z, Yan F
Journal of periodontal research 2023 Apr;58(2):444-455
Journal of periodontal research 2023 Apr;58(2):444-455
Effects of phase-transited lysozyme on adhesion, migration and odontogenic differentiation of human dental pulp cells: An in vitro study.
Zhao J, Zhou Y, Yan J, Liu J, Wang L, Zhang X, Lou Y, Que K
International endodontic journal 2023 Apr;56(4):475-485
International endodontic journal 2023 Apr;56(4):475-485
Bipotent transitional liver progenitor cells contribute to liver regeneration.
Pu W, Zhu H, Zhang M, Pikiolek M, Ercan C, Li J, Huang X, Han X, Zhang Z, Lv Z, Li Y, Liu K, He L, Liu X, Heim MH, Terracciano LM, Tchorz JS, Zhou B
Nature genetics 2023 Apr;55(4):651-664
Nature genetics 2023 Apr;55(4):651-664
YBX1 regulates the survival of chronic myeloid leukemia stem cells by modulating m(6)A-mediated YWHAZ stability.
Chai J, Wang Q, Qiu Q, Han G, Chen Y, Li W, Zhang H
Cellular oncology (Dordrecht, Netherlands) 2023 Apr;46(2):451-464
Cellular oncology (Dordrecht, Netherlands) 2023 Apr;46(2):451-464
Hyperthermia promotes degradation of the acute promyelocytic leukemia driver oncoprotein ZBTB16/RARα.
Wang QQ, Hussain L, Yu PH, Yang C, Zhu CY, Ma YF, Wang SC, Yang T, Kang YY, Yu WJ, Maimaitiyiming Y, Naranmandura H
Acta pharmacologica Sinica 2023 Apr;44(4):822-831
Acta pharmacologica Sinica 2023 Apr;44(4):822-831
Regulation of CD8(+) T cells infiltration and immunotherapy by circMGA/HNRNPL complex in bladder cancer.
Sun J, Zhang H, Wei W, Xiao X, Huang C, Wang L, Zhong H, Jiang Y, Zheng F, Yang H, Jiang G, Zhang X
Oncogene 2023 Apr;42(15):1247-1262
Oncogene 2023 Apr;42(15):1247-1262
Muscone promotes functional recovery by facilitating microglia polarization into M2 phenotype through PPAR-γ pathway after ischemic stroke.
Liu F, Cao L, Hu S, Ye H, Wu Q, Wu L
Cellular immunology 2023 Apr;386:104704
Cellular immunology 2023 Apr;386:104704
Identification of the CCL2 PI3K/Akt axis involved in autophagy and apoptosis after spinal cord injury.
Fang S, Tang H, Li MZ, Chu JJ, Yin ZS, Jia QY
Metabolic brain disease 2023 Apr;38(4):1335-1349
Metabolic brain disease 2023 Apr;38(4):1335-1349
p53 inhibits the Urea cycle and represses polyamine biosynthesis in glioma cell lines.
Zhao Y, Chen Y, Wei L, Ran J, Wang K, Zhu S, Liu Q
Metabolic brain disease 2023 Apr;38(4):1143-1153
Metabolic brain disease 2023 Apr;38(4):1143-1153
Deletion of the tyrosine phosphatase Shp2 in cervical cancer cells promotes reprogramming of glutamine metabolism.
Gao X, Kang J, Li X, Chen C, Luo D
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Apr;37(4):e22880
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Apr;37(4):e22880
Kcnma1 is involved in mitochondrial homeostasis in diabetes-related skeletal muscle atrophy.
Gao SY, Liu YP, Wen R, Huang XM, Li P, Yang YH, Yang N, Zhang TN
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Apr;37(4):e22866
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Apr;37(4):e22866
Renal CD81 interacts with sodium potassium 2 chloride cotransporter and sodium chloride cotransporter in rats with lipopolysaccharide-induced preeclampsia.
Wang P, Zhu G, Wu Q, Shen L, Liu D, Wang Z, Wang W, Ren Z, Jia Y, Liu M, Xue Y, Ji D, Hu Y, Yu Y, Wang X
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Apr;37(4):e22834
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Apr;37(4):e22834
Protective Roles of Xijiao Dihuang Tang on Coronary Artery Injury in Kawasaki Disease.
Zhang J, Zhuge Y, Rong X, Ni C, Niu C, Wen Z, Lin H, Chu M, Jia C
Cardiovascular drugs and therapy 2023 Apr;37(2):257-270
Cardiovascular drugs and therapy 2023 Apr;37(2):257-270
MiR-155 promotes inflammation and apoptosis via targeting SIRT1 in hypoxic-ischemic brain damage.
Ke F, Wang H, Geng J, Jing X, Fang F, Fang C, Zhang BH
Experimental neurology 2023 Apr;362:114317
Experimental neurology 2023 Apr;362:114317
Circular RNA circFBXO7 attenuates non-small cell lung cancer tumorigenesis by sponging miR-296-3p to facilitate KLF15-mediated transcriptional activation of CDKN1A.
Wang ZH, Ye LL, Xiang X, Wei XS, Niu YR, Peng WB, Zhang SY, Zhang P, Xue QQ, Wang HL, Du YH, Liu Y, Ai JQ, Zhou Q
Translational oncology 2023 Apr;30:101635
Translational oncology 2023 Apr;30:101635
The aryl sulfonamide indisulam inhibits gastric cancer cell migration by promoting the ubiquitination and degradation of the transcription factor ZEB1.
Lu J, Li D, Jiang H, Li Y, Lu C, Chen T, Wang Y, Wang X, Sun W, Pu Z, Qiao C, Ma J, Xu G
The Journal of biological chemistry 2023 Apr;299(4):103025
The Journal of biological chemistry 2023 Apr;299(4):103025
Hypermethylation of HIC2 is a potential prognostic biomarker and tumor suppressor of glioma based on bioinformatics analysis and experiments.
Luo F, Liao Y, Cao E, Yang Y, Tang K, Zhou D, Zhou D, Cai H
CNS neuroscience & therapeutics 2023 Apr;29(4):1154-1167
CNS neuroscience & therapeutics 2023 Apr;29(4):1154-1167
METTL3/14 and IL-17 signaling contribute to CEBPA-DT enhanced oral cancer cisplatin resistance.
Qiao X, Zhu L, Song R, Shang C, Guo Y
Oral diseases 2023 Apr;29(3):942-956
Oral diseases 2023 Apr;29(3):942-956
MicroRNAs of extracellular vesicles derived from mesenchymal stromal cells alleviate inflammation in dry eye disease by targeting the IRAK1/TAB2/NF-κB pathway.
Wang L, Wang X, Chen Q, Wei Z, Xu X, Han D, Zhang Y, Chen Z, Liang Q
The ocular surface 2023 Apr;28:131-140
The ocular surface 2023 Apr;28:131-140
Kaempferol promotes melanogenesis and reduces oxidative stress in PIG1 normal human skin melanocytes.
Xie Y, Mei X, Shi W
Journal of cellular and molecular medicine 2023 Apr;27(7):982-990
Journal of cellular and molecular medicine 2023 Apr;27(7):982-990
LPS inhibits TRIM65 expression in macrophages and C57BL/6J mouse by activating the ERK1/2 signaling pathway.
Zeng X, Deng X, Ni Y, Bi H, Jiang M, Wang D, Dong P, Xiao Y, Jiang M
Experimental and therapeutic medicine 2023 Apr;25(4):188
Experimental and therapeutic medicine 2023 Apr;25(4):188
DAB2 promotes pulmonary fibrosis and may act as an intermediate between IGF‑1R and PI3K/AKT signaling pathways.
Liang CL, Li XL, Quan XJ, Zhang L
Experimental and therapeutic medicine 2023 Apr;25(4):183
Experimental and therapeutic medicine 2023 Apr;25(4):183
Protective effect of L‑carnitine against oxidative stress injury in human ovarian granulosa cells.
Li X, Wu X, Ma T, Zhang Y, Sun P, Qi D, Ma H
Experimental and therapeutic medicine 2023 Apr;25(4):161
Experimental and therapeutic medicine 2023 Apr;25(4):161
Doublecortin-like kinase 2 promotes breast cancer cell invasion and metastasis.
He Y, Dai X, Li S, Zhang X, Gong K, Song K, Shi J
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 2023 Apr;25(4):1102-1113
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 2023 Apr;25(4):1102-1113
Inhibition of mitochondrial VDAC1 oligomerization alleviates apoptosis and necroptosis of retinal neurons following OGD/R injury.
Wan H, Yan YD, Hu XM, Shang L, Chen YH, Huang YX, Zhang Q, Yan WT, Xiong K
Annals of anatomy = Anatomischer Anzeiger : official organ of the Anatomische Gesellschaft 2023 Apr;247:152049
Annals of anatomy = Anatomischer Anzeiger : official organ of the Anatomische Gesellschaft 2023 Apr;247:152049
Geranylgeranylacetone-induced heat shock protein70 expression reduces retinal ischemia-reperfusion injury through PI3K/AKT/mTOR signaling.
Zhang L, Xue K, Fan P, Chen C, Hu J, Huang J, Lu W, Xu J, Xu S, Ran J, Zhu S, Gan S
Experimental eye research 2023 Apr;229:109416
Experimental eye research 2023 Apr;229:109416
Osteogenic and anti-inflammatory effects of SLA titanium substrates doped with chitosan-stabilized selenium nanoparticles via a covalent coupling strategy.
Xu Y, Shen Z, Zhou Y, Zhou YH, Zhou JY, Qian XN, Wei YW, Qiu J
Colloids and surfaces. B, Biointerfaces 2023 Apr;224:113217
Colloids and surfaces. B, Biointerfaces 2023 Apr;224:113217
RNA-Seq-based transcriptomics analysis during the photodynamic therapy of primary cells in secondary hyperparathyroidism.
Wen Y, Zeng L, Chen Q, Li Y, Fu M, Wang Z, Liu H, Li X, Huang P, Wu W, Zou Q, Yi W
Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 2023 Apr;22(4):905-917
Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 2023 Apr;22(4):905-917
Poly-L-Lactic acid increases collagen gene expression and synthesis in cultured dermal fibroblast (Hs68) through the TGF-β/Smad pathway.
Zhu W, Dong C
Journal of cosmetic dermatology 2023 Apr;22(4):1213-1219
Journal of cosmetic dermatology 2023 Apr;22(4):1213-1219
Derivation and comprehensive analysis of ageing-related genes in intervertebral disc degeneration for prediction and immunology.
Xu S, Fu H, Weng S, Gu X, Li J
Mechanisms of ageing and development 2023 Apr;211:111794
Mechanisms of ageing and development 2023 Apr;211:111794
Nitrovin (difurazone), an antibacterial growth promoter, induces ROS-mediated paraptosis-like cell death by targeting thioredoxin reductase 1 (TrxR1).
Zhao L, Zhong B, Zhu Y, Zheng H, Wang X, Hou Y, Lu JJ, Ai N, Guo X, Ge W, Ma YY, Chen X
Biochemical pharmacology 2023 Apr;210:115487
Biochemical pharmacology 2023 Apr;210:115487
CCL17 drives fibroblast activation in the progression of pulmonary fibrosis by enhancing the TGF-β/Smad signaling.
Wang QR, Liu SS, Min JL, Yin M, Zhang Y, Zhang Y, Tang XN, Li X, Liu SS
Biochemical pharmacology 2023 Apr;210:115475
Biochemical pharmacology 2023 Apr;210:115475
The RSK2-RPS6 axis promotes axonal regeneration in the peripheral and central nervous systems.
Decourt C, Schaeffer J, Blot B, Paccard A, Excoffier B, Pende M, Nawabi H, Belin S
PLoS biology 2023 Apr;21(4):e3002044
PLoS biology 2023 Apr;21(4):e3002044
Effects of Selenoprotein S Knockdown on Endoplasmic Reticulum Stress in ATDC5 Cells and Gene Expression Profiles in Hypertrophic Chondrocytes.
Wang H, Li Z, Liu Y, Zhang M, Shi Y, Zhang Y, Mi G, Wang M, He Y, Chen Y, Chen C, Chen J
Biological trace element research 2023 Apr;201(4):1965-1976
Biological trace element research 2023 Apr;201(4):1965-1976
TSG-6 inhibits hypertrophic scar fibroblast proliferation by regulating IRE1α/TRAF2/NF-κB signalling.
Ma L, Hua L, Yu W, Ke L, Li LY
International wound journal 2023 Apr;20(4):1008-1019
International wound journal 2023 Apr;20(4):1008-1019
Mechanisms regarding respiratory toxicity triggered by accumulation of ROS in carp exposed to difenoconazole.
Feng H, Chen H, Qiang J, Xu B, Wu X, Pan E, Yang H, Li X, Zhang J, Dong J
Pesticide biochemistry and physiology 2023 Apr;191:105343
Pesticide biochemistry and physiology 2023 Apr;191:105343
FOXP3+ macrophage represses acute ischemic stroke-induced neural inflammation.
Cai W, Hu M, Li C, Wu R, Lu D, Xie C, Zhang W, Li T, Shen S, Huang H, Qiu W, Liu Q, Lu Y, Lu Z
Autophagy 2023 Apr;19(4):1144-1163
Autophagy 2023 Apr;19(4):1144-1163
FGFR2 upregulates PAI-1 via JAK2/STAT3 signaling to induce M2 polarization of macrophages in colorectal cancer.
Li Y, Shi Y, Zhang X, Li P, Ma L, Hu P, Xu L, Dai Y, Xia S, Qiu H
Biochimica et biophysica acta. Molecular basis of disease 2023 Apr;1869(4):166665
Biochimica et biophysica acta. Molecular basis of disease 2023 Apr;1869(4):166665
CDC20 inhibition alleviates fibrotic response of renal tubular epithelial cells and fibroblasts by regulating nuclear translocation of β-catenin.
He J, Xu S, Jiang M, Wang T, Zhang Y, Jia Z, Bai M, Zhang A
Biochimica et biophysica acta. Molecular basis of disease 2023 Apr;1869(4):166663
Biochimica et biophysica acta. Molecular basis of disease 2023 Apr;1869(4):166663
Vagus nerve stimulation is a potential treatment for ischemic stroke.
Liu YL, Wang SR, Ma JX, Yu LH, Jia GW
Neural regeneration research 2023 Apr;18(4):825-831
Neural regeneration research 2023 Apr;18(4):825-831
Hypoxic postconditioning restores mitophagy against transient global cerebral ischemia via Parkin-induced posttranslational modification of TBK1.
Wen H, Zuo Y, Li L, Zhan L, Xue J, Sun W, Xu E
Neurobiology of disease 2023 Apr;179:106043
Neurobiology of disease 2023 Apr;179:106043
The Mechanism of the Anti-Cardiac Hypertrophy Effect of Glycyrrhizic Acid Is Related to Reducing STIM1-Dependent Store-Operated Calcium Entry.
Cheng X, Huang L
Bulletin of experimental biology and medicine 2023 Apr;174(6):701-706
Bulletin of experimental biology and medicine 2023 Apr;174(6):701-706
1,3-dichloro-2-propanol caused lipid droplets accumulation by suppressing neutral lipases via BMAL1 in hepatocytes.
Fan Y, Lu J, Fan J, Guan S
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2023 Apr;174:113670
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2023 Apr;174:113670
Repurposed benzydamine targeting CDK2 suppresses the growth of esophageal squamous cell carcinoma.
Zhou Y, He X, Jiang Y, Wang Z, Yu Y, Wu W, Zhang C, Li J, Guo Y, Chen X, Liu Z, Zhao J, Liu K, Dong Z
Frontiers of medicine 2023 Apr;17(2):290-303
Frontiers of medicine 2023 Apr;17(2):290-303
NETO2 promotes melanoma progression via activation of the Ca(2+)/CaMKII signaling pathway.
Zhu S, Zhang X, Guo Y, Tang L, Zhou Z, Chen X, Peng C
Frontiers of medicine 2023 Apr;17(2):263-274
Frontiers of medicine 2023 Apr;17(2):263-274
BMAL1 regulates MUC1 overexpression in ovalbumin-induced asthma.
Tang L, Zhang X, Xu Y, Liu L, Sun X, Wang B, Yu K, Zhang H, Zhao X, Wang X
Molecular immunology 2023 Apr;156:77-84
Molecular immunology 2023 Apr;156:77-84
Preparation of tanshinone II(A) self-soluble microneedles and its inhibition on proliferation of human skin fibroblasts.
Zhan Y, Xu X, Luo X, Liu R, Lin Y, Zhao P, Shi J
Chinese herbal medicines 2023 Apr;15(2):251-262
Chinese herbal medicines 2023 Apr;15(2):251-262
P2X4 receptor modulates gut inflammation and favours microbial homeostasis in colitis.
Zhong P, Wu H, Ma Y, Xu X, Jiang Y, Jin C, Zhu Q, Liu X, Suo Z, Wang J
Clinical and translational medicine 2023 Apr;13(4):e1227
Clinical and translational medicine 2023 Apr;13(4):e1227
Neutralization of interleukin-11 attenuates silica particles-induced pulmonary inflammation and fibrosis in vivo.
Ma J, Xie Y, Xu Y, Gu P, Zhang Y, Fan L, Zhou Y, Wang H, Zhou T, He J, Wang D, Chen W
Journal of environmental sciences (China) 2023 Apr;126:772-783
Journal of environmental sciences (China) 2023 Apr;126:772-783
LINC00669 promotes lung adenocarcinoma growth by stimulating the Wnt/β-catenin signaling pathway.
Zhu J, Cao K, Zhang P, Ma J
Cancer medicine 2023 Apr;12(7):9005-9023
Cancer medicine 2023 Apr;12(7):9005-9023
Par14 interacts with the androgen receptor, augmenting both its transcriptional activity and prostate cancer proliferation.
Naito M, Ikeda K, Aoyama S, Kanamoto M, Akasaka Y, Kido Y, Nakanishi M, Kanna M, Yamamotoya T, Matsubara A, Hinata N, Asano T, Nakatsu Y
Cancer medicine 2023 Apr;12(7):8464-8475
Cancer medicine 2023 Apr;12(7):8464-8475
Autophagy-mediated circHIPK2 promotes lipopolysaccharide-induced astrocytic inflammation via SIGMAR1.
Huang R, Cai L, Ma X, Shen K
International immunopharmacology 2023 Apr;117:109907
International immunopharmacology 2023 Apr;117:109907
Blockade of neutrophil extracellular traps ameliorates toluene diisocyanate-induced steroid-resistant asthma.
Peng X, Li Y, Zhao W, Yang S, Huang J, Chen Y, Wang Y, Gong Z, Chen X, Yu C, Cai S, Zhao H
International immunopharmacology 2023 Apr;117:109719
International immunopharmacology 2023 Apr;117:109719
Suppression of androgen receptor signaling induces prostate cancer migration via activation of the CCL20-CCR6 axis.
Kano H, Izumi K, Hiratsuka K, Toriumi R, Nakagawa R, Aoyama S, Kamijima T, Shimada T, Naito R, Kadomoto S, Iwamoto H, Yaegashi H, Kawaguchi S, Nohara T, Shigehara K, Kadono Y, Saito Y, Nakagawa-Goto K, Yoshioka K, Nakata H, Lin WJ, Mizokami A
Cancer science 2023 Apr;114(4):1479-1490
Cancer science 2023 Apr;114(4):1479-1490
Circular RNA circ0104103 inhibits colorectal cancer progression through interactions with HuR and miR-373-5p.
Tan P, Sun H, Xu M, Liu X, Qin J, Nie J, Qin X, Wang S, Pan Y
Cancer science 2023 Apr;114(4):1396-1409
Cancer science 2023 Apr;114(4):1396-1409
Salvianolic acid A alleviates atherosclerosis by inhibiting inflammation through Trc8-mediated 3-hydroxy-3-methylglutaryl-coenzyme A reductase degradation.
Xie D, Song L, Xiang D, Gao X, Zhao W
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Apr;112:154694
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Apr;112:154694
Chordoma recruits and polarizes tumor-associated macrophages via secreting CCL5 to promote malignant progression.
Xu J, Shi Q, Lou J, Wang B, Wang W, Niu J, Guo L, Chen C, Yu Y, Huang Y, Guo W, Lan J, Zhu Y, Ren T, Tang X
Journal for immunotherapy of cancer 2023 Apr;11(4)
Journal for immunotherapy of cancer 2023 Apr;11(4)
Genetic Knockout of Fatty Acid Amide Hydrolase Ameliorates Cisplatin-Induced Nephropathy in Mice.
Chen C, Wang W, Raymond M, Ahmadinejad F, Poklis JL, Em B, Gewirtz DA, Lichtman AH, Li N
Molecular pharmacology 2023 Apr;103(4):230-240
Molecular pharmacology 2023 Apr;103(4):230-240
Biomimetic Remodeling of Microglial Riboflavin Metabolism Ameliorates Cognitive Impairment by Modulating Neuroinflammation.
Zhang M, Chen H, Zhang W, Liu Y, Ding L, Gong J, Ma R, Zheng S, Zhang Y
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Apr;10(12):e2300180
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Apr;10(12):e2300180
CDKAL1 Drives the Maintenance of Cancer Stem-Like Cells by Assembling the eIF4F Translation Initiation Complex.
Huang R, Yamamoto T, Nakata E, Ozaki T, Kurozumi K, Wei F, Tomizawa K, Fujimura A
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Apr;10(12):e2206542
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Apr;10(12):e2206542
EHBP1L1 Drives Immune Evasion in Renal Cell Carcinoma through Binding and Stabilizing JAK1.
Pan Y, Shu G, Fu L, Huang K, Zhou X, Gui C, Liu H, Jin X, Chen M, Li P, Cen J, Feng Z, Lu J, Chen Z, Li J, Xu Q, Wang Y, Liang H, Wang Z, Deng Q, Chen W, Luo J, Yang J, Zhang J, Wei J
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Apr;10(11):e2206792
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Apr;10(11):e2206792
Histone phosphorylation integrates the hepatic glucagon-PKA-CREB gluconeogenesis program in response to fasting.
Zhao Y, Li S, Chen Y, Wang Y, Wei Y, Zhou T, Zhang Y, Yang Y, Chen L, Liu Y, Hu C, Zhou B, Ding Q
Molecular cell 2023 Apr 6;83(7):1093-1108.e8
Molecular cell 2023 Apr 6;83(7):1093-1108.e8
SLFN5-mediated chromatin dynamics sculpt higher-order DNA repair topology.
Huang J, Wu C, Kloeber JA, Gao H, Gao M, Zhu Q, Chang Y, Zhao F, Guo G, Luo K, Dai H, Liu S, Huang Q, Kim W, Zhou Q, Zhu S, Wu Z, Tu X, Yin P, Deng M, Wang L, Yuan J, Lou Z
Molecular cell 2023 Apr 6;83(7):1043-1060.e10
Molecular cell 2023 Apr 6;83(7):1043-1060.e10
Harnessing matrix stiffness to engineer a bone marrow niche for hematopoietic stem cell rejuvenation.
Zhang X, Cao D, Xu L, Xu Y, Gao Z, Pan Y, Jiang M, Wei Y, Wang L, Liao Y, Wang Q, Yang L, Xu X, Gao Y, Gao S, Wang J, Yue R
Cell stem cell 2023 Apr 6;30(4):378-395.e8
Cell stem cell 2023 Apr 6;30(4):378-395.e8
Homeobox A3 and KDM6A cooperate in transcriptional control of aerobic glycolysis and glioblastoma progression.
Yang R, Zhang G, Dong Z, Wang S, Li Y, Lian F, Liu X, Li H, Wei X, Cui H
Neuro-oncology 2023 Apr 6;25(4):635-647
Neuro-oncology 2023 Apr 6;25(4):635-647
Protocatechuic aldehyde acts synergistically with dacarbazine to augment DNA double-strand breaks and promote apoptosis in cutaneous melanoma cells.
Pei J, Su Z, Zeng X, Zhong Y, Zhang Y, Yang Y, Lu Q, Li J, Deng Y
BMC complementary medicine and therapies 2023 Apr 6;23(1):111
BMC complementary medicine and therapies 2023 Apr 6;23(1):111
CMTR1 promotes colorectal cancer cell growth and immune evasion by transcriptionally regulating STAT3.
You AB, Yang H, Lai CP, Lei W, Yang L, Lin JL, Liu SC, Ding N, Ye F
Cell death & disease 2023 Apr 6;14(4):245
Cell death & disease 2023 Apr 6;14(4):245
PRMT3-mediated arginine methylation of IGF2BP1 promotes oxaliplatin resistance in liver cancer.
Shi Y, Niu Y, Yuan Y, Li K, Zhong C, Qiu Z, Li K, Lin Z, Yang Z, Zuo D, Qiu J, He W, Wang C, Liao Y, Wang G, Yuan Y, Li B
Nature communications 2023 Apr 6;14(1):1932
Nature communications 2023 Apr 6;14(1):1932
Dihydrocaffeic acid improves IL-1β-induced inflammation and cartilage degradation via inhibiting NF-κB and MAPK signalling pathways.
Lu R, Wang YG, Qu Y, Wang SX, Peng C, You H, Zhu W, Chen A
Bone & joint research 2023 Apr 6;12(4):259-273
Bone & joint research 2023 Apr 6;12(4):259-273
Progranulin inhibits phospholipase sPLA2-IIA to control neuroinflammation.
Du H, Yang C, Nana AL, Seeley WW, Smolka M, Hu F
bioRxiv : the preprint server for biology 2023 Apr 6;
bioRxiv : the preprint server for biology 2023 Apr 6;
PFO5DoDA disrupts hepatic homeostasis primarily through glucocorticoid signaling inhibition.
Wang C, Fu H, Yang J, Liu L, Zhang F, Yang C, Li H, Chen J, Li Q, Wang X, Ye Y, Sheng N, Guo Y, Dai J, Xu G, Liu X, Wang J
Journal of hazardous materials 2023 Apr 5;447:130831
Journal of hazardous materials 2023 Apr 5;447:130831
Goliath induces inflammation in obese mice by linking fatty acid β-oxidation to glycolysis.
Hao S, Zhang S, Ye J, Chen L, Wang Y, Pei S, Zhu Q, Xu J, Tao Y, Zhou N, Yin H, Duan CW, Mao C, Zheng M, Xiao Y
EMBO reports 2023 Apr 5;24(4):e56932
EMBO reports 2023 Apr 5;24(4):e56932
Epitranscriptic regulation of HRAS by N(6)-methyladenosine drives tumor progression.
Pan Y, Gu Y, Liu T, Zhang Q, Yang F, Duan L, Cheng S, Zhu X, Xi Y, Chang X, Ye Q, Gao S
Proceedings of the National Academy of Sciences of the United States of America 2023 Apr 4;120(14):e2302291120
Proceedings of the National Academy of Sciences of the United States of America 2023 Apr 4;120(14):e2302291120
Anti-inflammatory effect of Irisin on LPS-stimulated macrophages through inhibition of MAPK pathway.
Ma Y, Du Y, Yang J, He Q, Wang H, Lin X
Physiological research 2023 Apr 30;72(2):235-249
Physiological research 2023 Apr 30;72(2):235-249
Transcriptomic analysis: the protection of over-expression thioredoxin reductase 1 in Parkinson's disease.
Liu Z, Ye Q, Jiang Y
Chinese neurosurgical journal 2023 Apr 3;9(1):9
Chinese neurosurgical journal 2023 Apr 3;9(1):9
DNA damage repair kinase DNA-PK and cGAS synergize to induce cancer-related inflammation in glioblastoma.
Taffoni C, Marines J, Chamma H, Guha S, Saccas M, Bouzid A, Valadao AC, Maghe C, Jardine J, Park MK, Polak K, De Martino M, Vanpouille-Box C, Del Rio M, Gongora C, Gavard J, Bidère N, Song MS, Pineau D, Hugnot JP, Kissa K, Fontenille L, Blanchet FP, Vila IK, Laguette N
The EMBO journal 2023 Apr 3;42(7):e111961
The EMBO journal 2023 Apr 3;42(7):e111961
Persistent Lipid Accumulation Leads to Persistent Exacerbation of Endoplasmic Reticulum Stress and Inflammation in Progressive NASH via the IRE1α/TRAF2 Complex.
Lei N, Song H, Zeng L, Ji S, Meng X, Zhu X, Li X, Feng Q, Liu J, Mu J
Molecules (Basel, Switzerland) 2023 Apr 3;28(7)
Molecules (Basel, Switzerland) 2023 Apr 3;28(7)
The outer mitochondrial membrane protein TMEM11 demarcates spatially restricted BNIP3/BNIP3L-mediated mitophagy.
Gok MO, Connor OM, Wang X, Menezes CJ, Llamas CB, Mishra P, Friedman JR
The Journal of cell biology 2023 Apr 3;222(4)
The Journal of cell biology 2023 Apr 3;222(4)
Downregulation of AC092894.1 promotes oxaliplatin resistance in colorectal cancer via the USP3/AR/RASGRP3 axis.
Zheng Z, Wu M, Li H, Xu W, Yang M, Pan K, Ni Y, Jiang T, Zheng H, Jin X, Zhang Y, Ding L, Fu J
BMC medicine 2023 Apr 3;21(1):132
BMC medicine 2023 Apr 3;21(1):132
Crotonylation of GAPDH regulates human embryonic stem cell endodermal lineage differentiation and metabolic switch.
Zhang J, Shi G, Pang J, Zhu X, Feng Q, Na J, Ma W, Liu D, Songyang Z
Stem cell research & therapy 2023 Apr 3;14(1):63
Stem cell research & therapy 2023 Apr 3;14(1):63
Upregulation of carbonic anhydrase 1 beneficial for depressive disorder.
Cheng K, Wang Y, He Y, Tian Y, Li J, Chen C, Xu X, Wu Z, Yu H, Chen X, Wu Y, Song W, Dong Z, Xu H, Xie P
Acta neuropathologica communications 2023 Apr 3;11(1):59
Acta neuropathologica communications 2023 Apr 3;11(1):59
Glucose Transporter Glut1-Dependent Metabolic Reprogramming Regulates Lipopolysaccharide-Induced Inflammation in RAW264.7 Macrophages.
Cornwell A, Ziółkowski H, Badiei A
Biomolecules 2023 Apr 29;13(5)
Biomolecules 2023 Apr 29;13(5)
DEAD-Box Helicase 17 Promotes Amyloidogenesis by Regulating BACE1 Translation.
Liu Y, Zhou G, Song L, Wen Q, Xie S, Chen L, Wang L, Xie X, Chen X, Pu Y, Chen G
Brain sciences 2023 Apr 29;13(5)
Brain sciences 2023 Apr 29;13(5)
Synthesis of Lathyrol PROTACs and Evaluation of Their Anti-Inflammatory Activities.
Wang W, Liu Y, Xiong L, Sun D, Wang H, Song Z, Li Y, Li H, Chen L
Journal of natural products 2023 Apr 28;86(4):767-781
Journal of natural products 2023 Apr 28;86(4):767-781
LncRNA NR_003508 Suppresses Mycobacterium tuberculosis-Induced Programmed Necrosis via Sponging miR-346-3p to Regulate RIPK1.
Liu L, Yu Z, Ma Q, Yu J, Gong Z, Deng G, Wu X
International journal of molecular sciences 2023 Apr 28;24(9)
International journal of molecular sciences 2023 Apr 28;24(9)
8-Methoxyflindersine-Induced Apoptosis and Cell Cycle Disorder Involving MAPK Signaling Activation in Human Colorectal Cancer Cells.
Zhang D, Fu Y, Liu Y, Wu Y, Chen J, Zhang L, Wang R, Chen Z, Liu T
International journal of molecular sciences 2023 Apr 28;24(9)
International journal of molecular sciences 2023 Apr 28;24(9)
Design, Synthesis, and Antitumor Activity of Potent and Selective EGFR L858R/T790M Inhibitors and Identification of a Combination Therapy to Overcome Acquired Resistance in Models of Non-small-cell Lung Cancer.
Pei J, Wang G, Wang A, Wu C, Pan X, Shuai W, Bu F, Zhu Y, Wang Y, Ouyang L, Li W
Journal of medicinal chemistry 2023 Apr 27;66(8):5719-5752
Journal of medicinal chemistry 2023 Apr 27;66(8):5719-5752
Development of Orally Bioavailable Amidobenzimidazole Analogues Targeting Stimulator of Interferon Gene (STING) Receptor.
Chen NN, Zhang H, Zhu QS, Zeng T, Dai W, Zhou YL, Xin GF, Wu BD, Gong SJ, Jiang ZY, You QD, Xu XL
Journal of medicinal chemistry 2023 Apr 27;66(8):5584-5610
Journal of medicinal chemistry 2023 Apr 27;66(8):5584-5610
Repurposing of Doramectin as a New Anti-Zika Virus Agent.
Zhu Y, Liang M, Yu J, Zhang B, Zhu G, Huang Y, He Z, Yuan J
Viruses 2023 Apr 27;15(5)
Viruses 2023 Apr 27;15(5)
NSC-derived exosomes enhance therapeutic effects of NSC transplantation on cerebral ischemia in mice.
Zhang R, Mao W, Niu L, Bao W, Wang Y, Wang Y, Zhu Y, Yang Z, Chen J, Dong J, Cai M, Yuan Z, Song H, Li G, Zhang M, Xiong N, Wei J, Dong Z
eLife 2023 Apr 27;12
eLife 2023 Apr 27;12
Sleep deprivation exacerbates microglial reactivity and Aβ deposition in a TREM2-dependent manner in mice.
Parhizkar S, Gent G, Chen Y, Rensing N, Gratuze M, Strout G, Sviben S, Tycksen E, Zhang Q, Gilmore PE, Sprung R, Malone J, Chen W, Remolina Serrano J, Bao X, Lee C, Wang C, Landsness E, Fitzpatrick J, Wong M, Townsend R, Colonna M, Schmidt RE, Holtzman DM
Science translational medicine 2023 Apr 26;15(693):eade6285
Science translational medicine 2023 Apr 26;15(693):eade6285
YTHDF1 phase separation triggers the fate transition of spermatogonial stem cells by activating the IκB-NF-κB-CCND1 axis.
Fang Q, Tian GG, Wang Q, Liu M, He L, Li S, Wu J
Cell reports 2023 Apr 25;42(4):112403
Cell reports 2023 Apr 25;42(4):112403
Nuclear ATR lysine-tyrosylation protects against heart failure by activating DNA damage response.
Zhao R, Cai K, Yang JJ, Zhou Q, Cao W, Xiang J, Shen YH, Cheng LL, Zang WD, Lin Y, Yuan YY, Xu W, Tao H, Zhao SM, Zhao JY
Cell reports 2023 Apr 25;42(4):112400
Cell reports 2023 Apr 25;42(4):112400
PPDPF suppresses the development of hepatocellular carcinoma through TRIM21-mediated ubiquitination of RIPK1.
Wang YK, Ma N, Xu S, Huang JY, Ni QZ, Cao HJ, Zheng QW, Zhu B, Xia J, Zhang FK, Ding XF, Qiu XS, Chen TW, Wang K, Chen W, Li ZG, Cheng SQ, Xie D, Li JJ
Cell reports 2023 Apr 25;42(4):112340
Cell reports 2023 Apr 25;42(4):112340
Chromatin Remodelling Molecule ARID1A Determines Metastatic Heterogeneity in Triple-Negative Breast Cancer by Competitively Binding to YAP.
Wang Y, Chen X, Qiao X, Xie Y, Guo D, Li B, Cao J, Tao Z, Hu X
Cancers 2023 Apr 25;15(9)
Cancers 2023 Apr 25;15(9)
Strategy To Assess Zoonotic Potential Reveals Low Risk Posed by SARS-Related Coronaviruses from Bat and Pangolin.
Yang Y, Shen XR, Zhang YL, Jiang RD, Wang X, Guan ZQ, Li Q, Yao YL, Gong QC, Geng R, Wang Q, Zhu Y, Luo JY, Shi ZL, Zhang HL, Peng K, Zhou P
mBio 2023 Apr 25;14(2):e0328522
mBio 2023 Apr 25;14(2):e0328522
Production of mature myotubes in vitro improves the texture and protein quality of cultured pork.
Guan X, Yan Q, Ma Z, Zhou J
Food & function 2023 Apr 24;14(8):3576-3587
Food & function 2023 Apr 24;14(8):3576-3587
CHST2-mediated sulfation of MECA79 antigens is critical for breast cancer cell migration and metastasis.
Zhang D, Zhang Y, Zou X, Li M, Zhang H, Du Y, Wang J, Peng C, Dong C, Hou Z
Cell death & disease 2023 Apr 24;14(4):288
Cell death & disease 2023 Apr 24;14(4):288
RBM4 dictates ESCC cell fate switch from cellular senescence to glutamine-addiction survival through inhibiting LKB1-AMPK-axis.
Chen L, Zhang W, Chen D, Yang Q, Sun S, Dai Z, Li Z, Liang X, Chen C, Jiao Y, Zhi L, Zhao L, Zhang J, Liu X, Zhao J, Li M, Wang Y, Qi Y
Signal transduction and targeted therapy 2023 Apr 21;8(1):159
Signal transduction and targeted therapy 2023 Apr 21;8(1):159
FUT1-mediated terminal fucosylation acts as a new target to attenuate renal fibrosis.
Luo J, Mao K, Zhu Z, Ye J, Li L, Wang D, Zhou J, Lin F, Li J, Ye J
Molecular medicine (Cambridge, Mass.) 2023 Apr 21;29(1):55
Molecular medicine (Cambridge, Mass.) 2023 Apr 21;29(1):55
Progesterone prevents HGSOC by promoting precancerous cell pyroptosis via inducing fibroblast paracrine.
Wu N, Zhang X, Wang Z, Zhang X, Fang C, Li H, Zhu M, Wang Y, Liao Q, Chu TY, Wang J
iScience 2023 Apr 21;26(4):106523
iScience 2023 Apr 21;26(4):106523
Effects of lysate/tissue storage at -80°C on subsequently extracted EVs of epithelial ovarian cancer tissue origins.
Shen S, Shen Z, Wang C, Wu X, Wang L, Ye L, Zhang S, Cheng X
iScience 2023 Apr 21;26(4):106521
iScience 2023 Apr 21;26(4):106521
JLP/Foxk1/N-cadherin axis fosters a partial epithelial-mesenchymal transition state in epithelial tubular cells.
Tian M, Zhang L, Zhang M, Qiao L, Xu B, Li C, Liu S, Song Y, Wei Z, Wang Y, Wang H
iScience 2023 Apr 21;26(4):106396
iScience 2023 Apr 21;26(4):106396
Network pharmacology and experimental validation to reveal the target of matrine against PRRSV.
Zhao Y, Ling X, Zhang H, Sun P, Sun Y, Yin W, Fan K, Yang H, Zhong J, Zhang Z, Wang J, Li H, Sun N
iScience 2023 Apr 21;26(4):106371
iScience 2023 Apr 21;26(4):106371
AC010883.5 promotes cell proliferation, invasion, migration, and epithelial-to-mesenchymal transition in cervical cancer by modulating the MAPK signaling pathway.
Gan Q, Huang X, Zhao W, Liu H, Xu Y, Zhang X, Cheng J, Chen R
BMC cancer 2023 Apr 21;23(1):364
BMC cancer 2023 Apr 21;23(1):364
Gab2 plays a carcinogenic role in ovarian cancer by regulating CrkII.
Yin Y, Zhang L, Li Y, Zhang C, He A
Journal of ovarian research 2023 Apr 21;16(1):79
Journal of ovarian research 2023 Apr 21;16(1):79
[Overexpression of miR-431-5p impairs mitochondrial function and induces apoptosis in gastric cancer cells via the Bax/Bcl-2/caspase3 pathway].
Wu J, Deng Z, Zhu Y, Dou G, Li J, Huang L
Nan fang yi ke da xue xue bao = Journal of Southern Medical University 2023 Apr 20;43(4):537-543
Nan fang yi ke da xue xue bao = Journal of Southern Medical University 2023 Apr 20;43(4):537-543
Chemoproteomics-enabled discovery of a covalent molecular glue degrader targeting NF-κB.
King EA, Cho Y, Hsu NS, Dovala D, McKenna JM, Tallarico JA, Schirle M, Nomura DK
Cell chemical biology 2023 Apr 20;30(4):394-402.e9
Cell chemical biology 2023 Apr 20;30(4):394-402.e9
Host E3 ligase Hrd1 ubiquitinates and degrades H protein of canine distemper virus to inhibit viral replication.
Wang W, Bi Z, Song S
Veterinary research 2023 Apr 2;54(1):30
Veterinary research 2023 Apr 2;54(1):30
PHF14 enhances DNA methylation of SMAD7 gene to promote TGF-β-driven lung adenocarcinoma metastasis.
Tian H, Liu C, Yu J, Han J, Du J, Liang S, Wang W, Liu Q, Lian R, Zhu T, Wu S, Tao T, Ye Y, Zhao J, Yang Y, Zhu X, Cai J, Wu J, Li M
Cell discovery 2023 Apr 18;9(1):41
Cell discovery 2023 Apr 18;9(1):41
Promoted Skin Wound Healing by Tail-Amputated Eisenia foetida Proteins via the Ras/Raf/MEK/ERK Signaling Pathway.
Li T, Sun Y, Wang J, Zhang C, Sun Y
ACS omega 2023 Apr 18;8(15):13935-13943
ACS omega 2023 Apr 18;8(15):13935-13943
VEGFA mRNA-LNP promotes biliary epithelial cell-to-hepatocyte conversion in acute and chronic liver diseases and reverses steatosis and fibrosis.
Rizvi F, Lee YR, Diaz-Aragon R, So J, Florentino RM, Smith AR, Everton E, Ostrowska A, Jung K, Tam Y, Muramatsu H, Pardi N, Weissman D, Soto-Gutierrez A, Shin D, Gouon-Evans V
bioRxiv : the preprint server for biology 2023 Apr 18;
bioRxiv : the preprint server for biology 2023 Apr 18;
Effect of Matrix Metalloproteinase 23 Accelerating Wound Healing Induced by Hydroxybutyl Chitosan.
Xia H, Hu Q, Yang Y, Yuan H, Cai Y, Liu Z, Xu Z, Xiong Y, Zhou J, Ye Q, Zhong Z
ACS applied bio materials 2023 Apr 17;6(4):1460-1470
ACS applied bio materials 2023 Apr 17;6(4):1460-1470
Cadmium-induced Sertoli Cell Injury Through p38-MAPK and Related Signaling Proteins-A Study by RNA Sequencing.
Wang L, Li X, Bu T, Wu X, Li L, Gao S, Yun D, Zhang Y, Chen H, Sun F, Cheng CY
Endocrinology 2023 Apr 17;164(6)
Endocrinology 2023 Apr 17;164(6)
Human cytomegalovirus attenuates AKT activity by destabilizing insulin receptor substrate proteins.
Domma AJ, Goodrum FD, Moorman NJ, Kamil JP
bioRxiv : the preprint server for biology 2023 Apr 17;
bioRxiv : the preprint server for biology 2023 Apr 17;
Upregulated estrogen receptors impairs myogenesis and elevates adipogenesis related factor levels in the paravertebral muscles of patients with idiopathic scoliosis.
Shu Q, Yang G, Tang M, Guo C, Zhang H, Li J
Biochemical and biophysical research communications 2023 Apr 16;652:22-30
Biochemical and biophysical research communications 2023 Apr 16;652:22-30
Prolyl isomerase Pin1 promotes extracellular matrix production in hepatic stellate cells through regulating formation of the Smad3-TAZ complex.
Aoyama S, Kido Y, Kanamoto M, Naito M, Nakanishi M, Kanna M, Yamamotoya T, Asano T, Nakatsu Y
Experimental cell research 2023 Apr 15;425(2):113544
Experimental cell research 2023 Apr 15;425(2):113544
DJ-1 Protects auditory cells from cisplatin-induced ototoxicity via regulating apoptosis and autophagy.
Wang Y, Zhao H, Wang F, Nong H, Li Y, Xu Y, He M, Li J
Toxicology letters 2023 Apr 15;379:56-66
Toxicology letters 2023 Apr 15;379:56-66
Galectin-1 Regulates RNA Expression and Alternative Splicing of Angiogenic Genes in HUVECs.
Wei J, Wu Y, Sun Y, Chen D
Frontiers in bioscience (Landmark edition) 2023 Apr 14;28(4):74
Frontiers in bioscience (Landmark edition) 2023 Apr 14;28(4):74
Design and Synthesis of Triazole-Containing HDAC Inhibitors That Induce Antitumor Effects and Immune Response.
Sun N, Yang K, Yan W, Yao M, Yu C, Duan W, Gu X, Guo D, Jiang H, Xie C, Cheng J
Journal of medicinal chemistry 2023 Apr 13;66(7):4802-4826
Journal of medicinal chemistry 2023 Apr 13;66(7):4802-4826
DDB1 regulates the activation-induced apoptosis of T cells via downregulating the expression of histone methyltransferase SETD7.
Wu R, Wu X, Zou L, Zhou L, Mao Y
Medical oncology (Northwood, London, England) 2023 Apr 12;40(5):146
Medical oncology (Northwood, London, England) 2023 Apr 12;40(5):146
LCRMP-1 is required for spermatogenesis and stabilises spermatid F-actin organization via the PI3K-Akt pathway.
Chang JH, Chou CH, Wu JC, Liao KM, Luo WJ, Hsu WL, Chen XR, Yu SL, Pan SH, Yang PC, Su KY
Communications biology 2023 Apr 10;6(1):389
Communications biology 2023 Apr 10;6(1):389
Tenascin C(+) papillary fibroblasts facilitate neuro-immune interaction in a mouse model of psoriasis.
Cai X, Han M, Lou F, Sun Y, Yin Q, Sun L, Wang Z, Li X, Zhou H, Xu Z, Wang H, Deng S, Zheng X, Zhang T, Li Q, Zhou B, Wang H
Nature communications 2023 Apr 10;14(1):2004
Nature communications 2023 Apr 10;14(1):2004
Knockout of murine Lyplal1 confers sex-specific protection against diet-induced obesity.
Vohnoutka RB, Kuppa A, Hegde Y, Chen Y, Pant A, Tohme ME, Choi EK, McCarty SM, Bagchi DP, Du X, Chen Y, Chen VL, Mori H, Bielak LF, Maguire LH, Handelman SK, Sexton JZ, Saunders TL, Halligan BD, Speliotes EK
Journal of molecular endocrinology 2023 Apr 1;70(3)
Journal of molecular endocrinology 2023 Apr 1;70(3)
Development of Engineered CAR T Cells Targeting Tumor-Associated Glycoforms of MUC1 for the Treatment of Intrahepatic Cholangiocarcinoma.
Mao L, Su S, Li J, Yu S, Gong Y, Chen C, Hu Z, Huang X
Journal of immunotherapy (Hagerstown, Md. : 1997) 2023 Apr 1;46(3):89-95
Journal of immunotherapy (Hagerstown, Md. : 1997) 2023 Apr 1;46(3):89-95
Aristolochic acid I promotes the invasion and migration of hepatocellular carcinoma cells by activating the C3a/C3aR complement system.
Li Y, Zhu S, Xue M, Jing Y, Liu X, Cai D, Zhao Y, Bian Y, Zhang Z, Zhang L
Toxicology letters 2023 Apr 1;378:51-60
Toxicology letters 2023 Apr 1;378:51-60
Exosomal circCLIP1 regulates PM(2.5)-induced airway obstruction via targeting SEPT10 in vitro.
Zhu H, Tang X, Zhang H, Zhou M, Liu H, Chu H, Zhang Z
Ecotoxicology and environmental safety 2023 Apr 1;254:114750
Ecotoxicology and environmental safety 2023 Apr 1;254:114750
3,4-benzopyrene aggravates myocardial ischemia-reperfusion injury-induced pyroptosis through inhibition of autophagy-dependent NLRP3 degradation.
Huang KY, Liu S, Yu YW, Wu BS, Lin ZH, Zhu CX, Song DY, Xue YJ, Ji KT
Ecotoxicology and environmental safety 2023 Apr 1;254:114701
Ecotoxicology and environmental safety 2023 Apr 1;254:114701
SGLT2i alleviates epicardial adipose tissue inflammation by modulating ketone body-glyceraldehyde-3-phosphate dehydrogenase malonylation pathway.
Li L, Hua C, Liu X, Wang Y, Zhao L, Zhang Y, Wang L, Su P, Yang MF, Xie B
Journal of cardiovascular medicine (Hagerstown, Md.) 2023 Apr 1;24(4):232-243
Journal of cardiovascular medicine (Hagerstown, Md.) 2023 Apr 1;24(4):232-243
Precise pancreatic cancer therapy through targeted degradation of mutant p53 protein by cerium oxide nanoparticles.
Zhang H, Zhang W, Hu B, Qin X, Yi T, Ye Y, Huang X, Song Y, Yang Z, Qian J, Zhang Y
Journal of nanobiotechnology 2023 Apr 1;21(1):117
Journal of nanobiotechnology 2023 Apr 1;21(1):117
Gold nanoclusters conjugated berberine reduce inflammation and alleviate neuronal apoptosis by mediating M2 polarization for spinal cord injury repair.
Zhou Z, Li D, Fan X, Yuan Y, Wang H, Wang D, Mei X
Regenerative biomaterials 2022;9:rbab072
Regenerative biomaterials 2022;9:rbab072
Prognostic value of plasma adipokine chemerin in patients with coronary artery disease.
Wang B, Kou W, Ji S, Shen R, Ji H, Zhuang J, Zhao Y, Li B, Peng W, Yu X, Li H, Xu Y
Frontiers in cardiovascular medicine 2022;9:968349
Frontiers in cardiovascular medicine 2022;9:968349
Collagen peptide promotes DSS-induced colitis by disturbing gut microbiota and regulation of macrophage polarization.
Li X, Cui L, Feng G, Yu S, Shao G, He N, Li S
Frontiers in nutrition 2022;9:957391
Frontiers in nutrition 2022;9:957391
Endothelial G protein stimulatory α-subunit is a critical regulator of post-ischemic angiogenesis.
He L, Lu H, Chu J, Qin X, Gao J, Chen M, Weinstein LS, Yang J, Zhang Q, Zhang C, Zhang W
Frontiers in cardiovascular medicine 2022;9:941946
Frontiers in cardiovascular medicine 2022;9:941946
A rare case of arrhythmogenic right ventricular cardiomyopathy associated with LAMA2 mutation: A case report and literature review.
Wang Y, Fang Y, Zhang D, Li Y, Luo S
Frontiers in medicine 2022;9:922347
Frontiers in medicine 2022;9:922347
ACSL3 is a potential prognostic biomarker for immune infiltration in clear cell renal cell carcinoma.
Zhang C, Hu H, Huang R, Huang G, Xi X
Frontiers in surgery 2022;9:909854
Frontiers in surgery 2022;9:909854
A Prognostic Signature Consisting of Pyroptosis-Related Genes and SCAF11 for Predicting Immune Response in Breast Cancer.
Chu L, Yi Q, Yan Y, Peng J, Li Z, Jiang F, He Q, Ouyang L, Wu S, Fu C, Liu Y, Xu Z
Frontiers in medicine 2022;9:882763
Frontiers in medicine 2022;9:882763
Research on the Mechanism and Prevention of Hypertension Caused by Apatinib Through the RhoA/ROCK Signaling Pathway in a Mouse Model of Gastric Cancer.
Wang W, He Q, Li C, Zhuang C, Zhang H, Wang Q, Fan X, Qi M, Sun R, Yu J
Frontiers in cardiovascular medicine 2022;9:873829
Frontiers in cardiovascular medicine 2022;9:873829
Galectin-3 Inhibition Ameliorates Streptozotocin-Induced Diabetic Cardiomyopathy in Mice.
Zhu N, Zhu L, Huang B, Xiang W, Zhao X
Frontiers in cardiovascular medicine 2022;9:868372
Frontiers in cardiovascular medicine 2022;9:868372
Whole-Exome Sequencing Identifies a Novel Variant (c.1538T > C) of TNNI3K in Arrhythmogenic Right Ventricular Cardiomyopathy.
Xie T, Yang Y, Gong K, Luo Y, Guo H, Liu R, Wang L, Tan Z, Luo J, Xie L
Frontiers in cardiovascular medicine 2022;9:843837
Frontiers in cardiovascular medicine 2022;9:843837
Green Banana Flour Contributes to Gut Microbiota Recovery and Improves Colonic Barrier Integrity in Mice Following Antibiotic Perturbation.
Li P, Li M, Song Y, Huang X, Wu T, Xu ZZ, Lu H
Frontiers in nutrition 2022;9:832848
Frontiers in nutrition 2022;9:832848
Metformin Promotes Mechanical Stretch-Induced Skin Regeneration by Improving the Proliferative Activity of Skin-Derived Stem Cells.
Xiong S, Liu W, Song Y, Du J, Wang T, Zhang Y, Huang Z, He Q, Dong C, Yu Z, Ma X
Frontiers in medicine 2022;9:813917
Frontiers in medicine 2022;9:813917
Establishment of a New Abdominal Aortic Aneurysm Model in Rats by a Retroperitoneal Approach.
Zhu JX, Tang QQ, Zhou C, Shi XC, Yi SY, Yang Y
Frontiers in cardiovascular medicine 2022;9:808732
Frontiers in cardiovascular medicine 2022;9:808732
Bilateral Superior Cervical Sympathectomy Activates Signal Transducer and Activator of Transcription 3 Signal to Alleviate Myocardial Ischemia-Reperfusion Injury.
Li L, Gao J, Gao L, Li L, Zhang H, Zhao W, Xu S
Frontiers in cardiovascular medicine 2022;9:807298
Frontiers in cardiovascular medicine 2022;9:807298
Integrated Strategies of Diverse Feature Selection Methods Identify Aging-Based Reliable Gene Signatures for Ischemic Cardiomyopathy.
Song H, Chen S, Zhang T, Huang X, Zhang Q, Li C, Chen C, Chen S, Liu D, Wang J, Tu Y, Wu Y, Liu Y
Frontiers in molecular biosciences 2022;9:805235
Frontiers in molecular biosciences 2022;9:805235
Exploring the Mechanism of Hawthorn Leaves Against Coronary Heart Disease Using Network Pharmacology and Molecular Docking.
Ding J, Wu J, Wei H, Li S, Huang M, Wang Y, Fang Q
Frontiers in cardiovascular medicine 2022;9:804801
Frontiers in cardiovascular medicine 2022;9:804801
Comprehensive Characterization of Ageing-Relevant Subtypes Associated With Different Tumorigenesis and Tumor Microenvironment in Prostate Cancer.
Huang L, Xu Z, Xie Y, Jiang S, Han W, Tang Z, Zhu Q
Frontiers in molecular biosciences 2022;9:803474
Frontiers in molecular biosciences 2022;9:803474
Bioinformatics-Guided Analysis Uncovers AOX1 as an Osteogenic Differentiation-Relevant Gene of Human Mesenchymal Stem Cells.
Sun L, Ma J, Chen J, Pan Z, Li L
Frontiers in molecular biosciences 2022;9:800288
Frontiers in molecular biosciences 2022;9:800288
Hypoglycemia-Exacerbated Mitochondrial Connexin 43 Accumulation Aggravates Cardiac Dysfunction in Diabetic Cardiomyopathy.
Wei X, Chang ACH, Chang H, Xu S, Xue Y, Zhang Y, Lei M, Chang ACY, Zhang Q
Frontiers in cardiovascular medicine 2022;9:800185
Frontiers in cardiovascular medicine 2022;9:800185
SS31 Ameliorates Oxidative Stress via the Restoration of Autophagic Flux to Protect Aged Mice From Hind Limb Ischemia.
Yang Q, Li C, Chen Q
Frontiers in cardiovascular medicine 2022;9:789331
Frontiers in cardiovascular medicine 2022;9:789331
Exosome-Derived From Sepsis Patients' Blood Promoted Pyroptosis of Cardiomyocytes by Regulating miR-885-5p/HMBOX1.
Tu GW, Ma JF, Li JK, Su Y, Luo JC, Hao GW, Luo MH, Cao YR, Zhang Y, Luo Z
Frontiers in cardiovascular medicine 2022;9:774193
Frontiers in cardiovascular medicine 2022;9:774193
IL-7-Treated Periodontal Ligament Cells Regulate Local Immune Homeostasis by Modulating Treg/Th17 Cell Polarization.
Yu XY, Zhang ZQ, Huang JC, Lin JY, Cai XP, Liu CF
Frontiers in medicine 2022;9:754341
Frontiers in medicine 2022;9:754341
CTB-193M12.5 Promotes Hepatocellular Carcinoma Progression via Enhancing NSD1-Mediated WNT10B/Wnt/β-Catenin Signaling Activation.
Zhang S, Jiang M, Cao H, Xiong J, Xu J
Journal of hepatocellular carcinoma 2022;9:553-569
Journal of hepatocellular carcinoma 2022;9:553-569
RNA Binding Motif Protein 3 Promotes Cell Metastasis and Epithelial-Mesenchymal Transition Through STAT3 Signaling Pathway in Hepatocellular Carcinoma.
Zhang L, Zhang Y, Shen D, Chen Y, Feng J, Wang X, Ma L, Liao Y, Tang L
Journal of hepatocellular carcinoma 2022;9:405-422
Journal of hepatocellular carcinoma 2022;9:405-422
Ticagrelor reduces doxorubicin-induced pyroptosis of rat cardiomyocytes by targeting GSK-3β/caspase-1.
Wang SH, Sun MJ, Ding SY, Liu CL, Wang JM, Han SN, Lin X, Li Q
Frontiers in cardiovascular medicine 2022;9:1090601
Frontiers in cardiovascular medicine 2022;9:1090601
miRNA-150_R-1 mediates the HIF-1/ErbB signaling pathway to regulate the adhesion of endometrial epithelial cells in cows experiencing retained placenta.
Lv C, Li Z, Wang Q, Wang Y, Zhao X, Zhang Y
Frontiers in veterinary science 2022;9:1037880
Frontiers in veterinary science 2022;9:1037880
Triptolide increases resistance to bile duct ligation-induced liver injury and fibrosis in mice by inhibiting RELB.
Yuan Z, Wang J, Zhang H, Miao Y, Tang Q, Yuan Z, Nong C, Duan Z, Zhang L, Jiang Z, Yu Q
Frontiers in nutrition 2022;9:1032722
Frontiers in nutrition 2022;9:1032722
Enhanced pathogenicity by up-regulation of A20 after avian leukemia subgroup a virus infection.
Chen X, Wang X, Yang Y, Fang C, Liu J, Liang X, Yang Y
Frontiers in veterinary science 2022;9:1031480
Frontiers in veterinary science 2022;9:1031480
Hydrogen sulfide against preeclampsia exposure-induced oxidative mitochondrial damage in HTR-8/SVneo cells.
Wang X, Yu S, Jian Y, Pan H, Guo J, Wu J, Guo W
Frontiers in cardiovascular medicine 2022;9:1023982
Frontiers in cardiovascular medicine 2022;9:1023982
Effects of insufficient serine on health and selenoprotein expression in rats and their offspring.
Liu Y, Wang J, Wang Q, Han F, Shi L, Han C, Huang Z, Xu L
Frontiers in nutrition 2022;9:1012362
Frontiers in nutrition 2022;9:1012362
Regulation of the Human IL-10RB Gene Expression by Sp8 and Sp9.
Luo S, Dong X, Guo S, Wang Q, Dai X, Jiang Y, Zhu W, Zhou W, Song W
Journal of Alzheimer's disease : JAD 2022;88(4):1469-1485
Journal of Alzheimer's disease : JAD 2022;88(4):1469-1485
Ubiquitin‑specific peptidase 53 promotes chronic constriction injury‑induced neuropathic pain through the RhoA/ROCK pathway.
Li Q, Li R, Chu X, An X, Chen M, Yu Y, Zhang L, Chen L, Zhu X
Acta neurobiologiae experimentalis 2022;82(4):468-476
Acta neurobiologiae experimentalis 2022;82(4):468-476
MicroRNA-128b mediates lipopolysaccharide-induced apoptosis via reactive oxygen species in human pulmonary microvascular endothelial cells.
Long G, Yang X, Ji C, Dong Y
Clinics (Sao Paulo, Brazil) 2022;77:100020
Clinics (Sao Paulo, Brazil) 2022;77:100020
Paradol Induces Cell Cycle Arrest and Apoptosis in Glioblastoma Cells.
Wang R, Liu T, Chen J, Zhang D
Nutrition and cancer 2022;74(8):3007-3014
Nutrition and cancer 2022;74(8):3007-3014
Astragaloside IV drug-loaded exosomes (AS-IV EXOs) derived from endothelial progenitor cells improve the viability and tube formation in high-glucose impaired human endothelial cells by promoting miR-214 expression.
Zou X, Xiao H, Bai X, Zou Y, Hu W, Lin X, Zhu C, Liang Y, Xiong W
Endokrynologia Polska 2022;73(2):336-345
Endokrynologia Polska 2022;73(2):336-345
7-Methylxanthine Influences the Behavior of ADORA2A-DRD2 Heterodimers in Human Retinal Pigment Epithelial Cells.
Fan Y, Li J, Huang L, Wang K, Zhao M
Ophthalmic research 2022;65(6):678-684
Ophthalmic research 2022;65(6):678-684
Identification and Verification of Ubiquitin D as a Gene Associated with Hepatitis C Virus-Induced Hepatocellular Carcinoma.
Li H, Liu S, Lin Y, Shi X, Du N, Yao J, Liu R, Du Y, Yang K
Intervirology 2022;65(4):195-205
Intervirology 2022;65(4):195-205
MiR-7015-3p Targets Nuclear Factor-Kappa-B-Inhibitor Alpha to Aggravate Hypoxia/Reoxygenation Injury in Cardiomyocytes Through the NF-κB Pathway.
Shen X, Tao J, Wang Z, Li G, Zhang Z, Li J, Diliar A
International heart journal 2022;63(5):881-892
International heart journal 2022;63(5):881-892
Sinapic Acid Alleviates Acute Pancreatitis in Association with Attenuation of Inflammation, Pyroptosis, and the AMPK/NF-[Formula: see text]B Signaling Pathway.
Huang ZW, Tan P, Yi XK, Chen H, Sun B, Shi H, Mou ZQ, Cheng YL, Li TX, Li Q, Fu WG
The American journal of Chinese medicine 2022;50(8):2185-2197
The American journal of Chinese medicine 2022;50(8):2185-2197
Bovine milk exosomes affected proliferation of macrophages under hypoxia.
Matic S, Dia VP
Current research in food science 2022;5:2108-2113
Current research in food science 2022;5:2108-2113
Demethylase FTO inhibits the development of prostate cancer by upregulating EGR2 expression in an m6A manner.
Wang Z, Sun H, Zhu H, Gu D, Chen X, Pan Y, Zheng B, Yang D
Turkish journal of biology = Turk biyoloji dergisi 2022;46(6):426-438
Turkish journal of biology = Turk biyoloji dergisi 2022;46(6):426-438
ETV6 Regulates Hemin-Induced Erythroid Differentiation of K562 Cells through Mediating the Raf/MEK/ERK Pathway.
Li Z, Sun MZ, Lv X, Guo C, Liu S
Biological & pharmaceutical bulletin 2022;45(3):250-259
Biological & pharmaceutical bulletin 2022;45(3):250-259
Torin1 restores proliferation rate in Charcot-Marie-Tooth disease type 2A cells harbouring MFN2 (mitofusin 2) mutation.
Zanfardino P, Amati A, Petracca EA, Santorelli FM, Petruzzella V
Acta myologica : myopathies and cardiomyopathies : official journal of the Mediterranean Society of Myology 2022;41(4):201-206
Acta myologica : myopathies and cardiomyopathies : official journal of the Mediterranean Society of Myology 2022;41(4):201-206
Regulation of lysosomal trafficking of progranulin by sortilin and prosaposin.
Du H, Zhou X, Feng T, Hu F
Brain communications 2022;4(1):fcab310
Brain communications 2022;4(1):fcab310
Hyperthermia promotes exosome secretion by regulating Rab7b while increasing drug sensitivity in adriamycin-resistant breast cancer.
Xu D, Tang WJ, Zhu YZ, Liu Z, Yang K, Liang MX, Chen X, Wu Y, Tang JH, Zhang W
International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group 2022;39(1):246-257
International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group 2022;39(1):246-257
Gynura segetum induces hepatic sinusoidal obstruction syndrome in mice by impairing autophagy.
Zhang H, Jia S, Jin L, Mb JY, Shen Z, Wu J, Yao X, Chen D, Zhang C, Yu S, Zhu N, Jin L, Yao X
Acta cirurgica brasileira 2022;36(11):e361104
Acta cirurgica brasileira 2022;36(11):e361104
Human mesenchymal stem cell derived exosomes inhibit the survival of human melanoma cells through modulating miR-138-5p/SOX4 pathway.
Wang X, Cui Z, Zeng B, Qiong Z, Long Z
Cancer biomarkers : section A of Disease markers 2022;34(4):533-543
Cancer biomarkers : section A of Disease markers 2022;34(4):533-543
Ubiquitination and degradation of MGMT by TRIM72 increases the sensitivity of uveal melanoma cells to Dacarbazine treatment.
Li X, Yang C, Luo N, Yang Y, Guo Y, Chen P, Cun B
Cancer biomarkers : section A of Disease markers 2022;34(2):275-284
Cancer biomarkers : section A of Disease markers 2022;34(2):275-284
Non-canonical Small GTPase RBJ Promotes NSCLC Progression Through the Canonical MEK/ERK Signaling Pathway.
Wang Y, Shen X, Wang Q, Guo Z, Hu L, Dong Z, Hu W
Current pharmaceutical design 2022;28(42):3446-3455
Current pharmaceutical design 2022;28(42):3446-3455
IL-33 Participates in the Development of Esophageal Adenocarcinoma.
Liu J, Liu L, Su Y, Wang Y, Zhu Y, Sun X, Guo Y, Shan J
Pathology oncology research : POR 2022;28:1610474
Pathology oncology research : POR 2022;28:1610474
Activated Hepatic Stellate Cells Promote the M1 to M2 Macrophage Transformation and Liver Fibrosis by Elevating the Histone Acetylation Level.
Chen J, Huang X, Huang Z, Cao Y
Disease markers 2022;2022:9883831
Disease markers 2022;2022:9883831
Targeting the LSD1-G9a-ER Stress Pathway as a Novel Therapeutic Strategy for Esophageal Squamous Cell Carcinoma.
Wang H, Song Z, Xie E, Chen J, Tang B, Wang F, Min J
Research (Washington, D.C.) 2022;2022:9814652
Research (Washington, D.C.) 2022;2022:9814652
Downregulation of HULC Induces Ferroptosis in Hepatocellular Carcinoma via Targeting of the miR-3200-5p/ATF4 Axis.
Guan L, Wang F, Wang M, Han S, Cui Z, Xi S, Xu H, Li S
Oxidative medicine and cellular longevity 2022;2022:9613095
Oxidative medicine and cellular longevity 2022;2022:9613095
Experimental Study on the Mechanism of Cinnamaldehyde Ameliorate Proteinuria Induced by Adriamycin.
He D, Li Q, Du G, Chen S, Zeng P
BioMed research international 2022;2022:9600450
BioMed research international 2022;2022:9600450
Huoxue Qianyang Qutan Recipe Protects against Early Renal Damage Induced by Obesity-Related Hypertension via the SIRT1/NF-κB/IL-6 Pathway: Integrating Network Pharmacology and Experimental Validation-Based Strategy.
Wang M, Li J, Gui M, Lu B, Yao L, Zhou X, Shi M, Hu L, Fu D
Evidence-based complementary and alternative medicine : eCAM 2022;2022:9599090
Evidence-based complementary and alternative medicine : eCAM 2022;2022:9599090
Guanxinping Tablets Inhibit ET-1-Induced Proliferation and Migration of MOVAS by Suppressing Activated PI3K/Akt/NF-κB Signaling Cascade.
Wu YY, Huang YL, Dai B, Liu JW, Han X
Evidence-based complementary and alternative medicine : eCAM 2022;2022:9485463
Evidence-based complementary and alternative medicine : eCAM 2022;2022:9485463
Tiaojing Cuyun Recipe Enhances Pregnancy Outcome via the VEGF/PI3K/AKT/eNOS Signaling Pathway in EID Mice.
Huang H, Xia L, Xia Y, Yan Y, Jiang Z, Zhao P, Dong L
Disease markers 2022;2022:9461444
Disease markers 2022;2022:9461444
Identification and Characterization of the Roles of circCASP9 in Gastric Cancer Based on a circRNA-miRNA-mRNA Regulatory Network.
Qin C, Zhang H, Guo X, Cheng A, Liu H, Wang Z
Oxidative medicine and cellular longevity 2022;2022:9416825
Oxidative medicine and cellular longevity 2022;2022:9416825
Loureirin B Alleviates Myocardial Ischemia/Reperfusion Injury via Inhibiting PAI-1/TGF-β1/Smad Signaling Pathway.
Kong F, Zhao M
Evidence-based complementary and alternative medicine : eCAM 2022;2022:9128210
Evidence-based complementary and alternative medicine : eCAM 2022;2022:9128210
Scrapie-Responsive Gene 1 Promotes Chondrogenic Differentiation of Umbilical Cord Mesenchymal Stem Cells via Wnt5a.
Zhou Y, Zheng T, Li L, Guo Y, Xiao J, Wang J, Du Z, Gao H, Tang W, Yang L, Hu H, Wang X, Meng M, Hou Z
Stem cells international 2022;2022:9124277
Stem cells international 2022;2022:9124277
Cell-Dependent Pathogenic Roles of Filamin B in Different Skeletal Malformations.
Wu H, Wang Y, Chen X, Yao Y, Zhao W, Fang L, Sun X, Wang N, Jiang J, Gao L, Zhao J, Xu C
Oxidative medicine and cellular longevity 2022;2022:8956636
Oxidative medicine and cellular longevity 2022;2022:8956636
Ketamine Promotes LPS-Induced Pulmonary Autophagy and Reduces Apoptosis through the AMPK/mTOR Pathway.
Cao J, Mai H, Chen Y, Yuan R, Fang E, Liu M, Fu C
Contrast media & molecular imaging 2022;2022:8713701
Contrast media & molecular imaging 2022;2022:8713701
LncRNA-MALAT1 Regulates Cancer Glucose Metabolism in Prostate Cancer via MYBL2/mTOR Axis.
Mu X, Shen Z, Lin Y, Xiao J, Xia K, Xu C, Chen B, Shi R, Zhu A, Sun X, Tao T, Song X, Xuan Q
Oxidative medicine and cellular longevity 2022;2022:8693259
Oxidative medicine and cellular longevity 2022;2022:8693259
Dihydroartemisinin Attenuated Intervertebral Disc Degeneration via Inhibiting PI3K/AKT and NF-κB Signaling Pathways.
Liao Z, Su D, Liu H, Xu C, Wu J, Chen Y, Guo W, Zhang S, Li Z, Ke X, Wang T, Zhou T, Su P
Oxidative medicine and cellular longevity 2022;2022:8672969
Oxidative medicine and cellular longevity 2022;2022:8672969
Pretreatment with Shenmai Injection Protects against Coronary Microvascular Dysfunction.
Zheng Z, Yu Z, Xu B, Zhou Y, Xing Y, Li Q, Tang W, Peng F
Evidence-based complementary and alternative medicine : eCAM 2022;2022:8630480
Evidence-based complementary and alternative medicine : eCAM 2022;2022:8630480
Nr2f2 Overexpression Aggravates Ferroptosis and Mitochondrial Dysfunction by Regulating the PGC-1α Signaling in Diabetes-Induced Heart Failure Mice.
Miao W, Chen M, Chen M, Cui C, Zhu Y, Luo X, Wu B
Mediators of inflammation 2022;2022:8373389
Mediators of inflammation 2022;2022:8373389
Exosomes Derived from Baicalin-Pretreated Mesenchymal Stem Cells Alleviate Hepatocyte Ferroptosis after Acute Liver Injury via the Keap1-NRF2 Pathway.
Zhao S, Huang M, Yan L, Zhang H, Shi C, Liu J, Zhao S, Liu H, Wang B
Oxidative medicine and cellular longevity 2022;2022:8287227
Oxidative medicine and cellular longevity 2022;2022:8287227
Targeting Circulating lncRNA ENST00000538705.1 Relieves Acute Coronary Syndrome via Modulating ALOX15.
Chen H, Huang S, Guan F, Han S, Ye F, Li X, You L
Disease markers 2022;2022:8208471
Disease markers 2022;2022:8208471
AdipoR1 Regulates Ionizing Radiation-Induced Ferroptosis in HCC cells through Nrf2/xCT Pathway.
Feng H, Liu Y, Gan Y, Li M, Liu R, Liang Z, Liu L, Li L, Chen H, Li G, Tian Z, Liu X, Ma S
Oxidative medicine and cellular longevity 2022;2022:8091464
Oxidative medicine and cellular longevity 2022;2022:8091464
circIFT80 Functions as a ceRNA for miR-142, miR-568, and miR-634 and Promotes the Progression of Colorectal Cancer by Targeting β-Catenin.
Liu N, Jiang F, Chen Z, Liu X, Zhiming FU, Wang BC, Lv Y
Disease markers 2022;2022:8081246
Disease markers 2022;2022:8081246
The Overexpression of TOB1 Induces Autophagy in Gastric Cancer Cells by Secreting Exosomes.
Wang Y, Song Y, Zhou L, Wang M, Wang D, Bai J, Fu S, Yu J
Disease markers 2022;2022:7925097
Disease markers 2022;2022:7925097
Effects of Escin on Oxidative Stress and Apoptosis of H9c2 Cells Induced by H(2)O(2).
Qiao P, Zhang B, Liu X, Xu J, Li X
Disease markers 2022;2022:7765353
Disease markers 2022;2022:7765353
Network Pharmacology Prediction and Molecular Docking-Based Strategy to Discover the Potential Pharmacological Mechanism of Wen-Yu-Jin against Pulmonary Fibrosis in a Mouse Model.
Wang L, Zhu W, Sun R, Liu J, Ma Q, Zhang B, Shi Y
Evidence-based complementary and alternative medicine : eCAM 2022;2022:7753508
Evidence-based complementary and alternative medicine : eCAM 2022;2022:7753508
HOTAIRM1 Maintained the Malignant Phenotype of tMSCs Transformed by GSCs via E2F7 by Binding to FUS.
Liu L, Zhou Y, Dong X, Li S, Cheng S, Li H, Li Y, Yuan J, Wang L, Dong J
Journal of oncology 2022;2022:7734413
Journal of oncology 2022;2022:7734413
Dexmedetomidine Can Enhance PINK1/Parkin-Mediated Mitophagy in MPTP-Induced PD Mice Model by Activating AMPK.
Chen C, Chen Y, Liu T, Song D, Ma D, Cheng O
Oxidative medicine and cellular longevity 2022;2022:7511393
Oxidative medicine and cellular longevity 2022;2022:7511393
Calycosin Improves Intestinal Mucosal Barrier Function after Gastrectomy in Rats through Alleviating Bacterial Translocation, Inflammation, and Oxidative Stress.
Peng H, Jin L, Zhang Q, Shen Y, Wang Z, Zhou F, Yu Q
Evidence-based complementary and alternative medicine : eCAM 2022;2022:7412331
Evidence-based complementary and alternative medicine : eCAM 2022;2022:7412331
TRIP13 Induces Nedaplatin Resistance in Esophageal Squamous Cell Carcinoma by Enhancing Repair of DNA Damage and Inhibiting Apoptosis.
Zhang LT, Ke LX, Wu XY, Tian HT, Deng HZ, Xu LY, Li EM, Long L
BioMed research international 2022;2022:7295458
BioMed research international 2022;2022:7295458
Protective Effect of Photobiomodulation against Hydrogen Peroxide-Induced Oxidative Damage by Promoting Autophagy through Inhibition of PI3K/AKT/mTOR Pathway in MC3T3-E1 Cells.
Zuo X, Wei X, Ju C, Wang X, Zhang Z, Ma Y, Zhu Z, Li X, Song Z, Luo L, Hu X, Wang Z
Oxidative medicine and cellular longevity 2022;2022:7223353
Oxidative medicine and cellular longevity 2022;2022:7223353
APY0201 Represses Tumor Growth through Inhibiting Autophagy in Gastric Cancer Cells.
Li H, Jin X, Zhang S, Li B, Zeng L, He Y, Zhang C
Journal of oncology 2022;2022:7104592
Journal of oncology 2022;2022:7104592
Catalpol Regulates Oligodendrocyte Regeneration and Remyelination by Activating the GEF-Cdc42/Rac1 Signaling Pathway in EAE Mice.
Wu M, Kang Q, Kang Y, Tong Y, Yang T, Fan Y
Evidence-based complementary and alternative medicine : eCAM 2022;2022:7074157
Evidence-based complementary and alternative medicine : eCAM 2022;2022:7074157
Aspirin Exerts Its Antitumor Effect in Esophageal Squamous Cell Carcinoma by Downregulating the Expression of ATAD2 and KIF4A.
Zhang M, Ren Z, Wang X, Liu C, Zheng Z, Zhao J, Liu H
Analytical cellular pathology (Amsterdam) 2022;2022:7005328
Analytical cellular pathology (Amsterdam) 2022;2022:7005328
Mechanical Stretch Promotes Macrophage Polarization and Inflammation via the RhoA-ROCK/NF-κB Pathway.
Tu PC, Pan YL, Liang ZQ, Yang GL, Wu CJ, Zeng L, Wang LN, Sun J, Liu MM, Yuan YF, Guo Y, Ma Y
BioMed research international 2022;2022:6871269
BioMed research international 2022;2022:6871269
Bellidifolin Inhibits SRY-Related High Mobility Group-Box Gene 9 to Block TGF-β Signalling Activation to Ameliorate Myocardial Fibrosis.
Yao TT, Yang HX, Sun JH, Zhang Y, Zhang Y, Song QH, Liu WZ, Zhang JJ, Li AY
Evidence-based complementary and alternative medicine : eCAM 2022;2022:6841276
Evidence-based complementary and alternative medicine : eCAM 2022;2022:6841276
Interleukin-19 Aggravates Pulmonary Fibrosis via Activating Fibroblast through TGF-β/Smad Pathway.
Wang Y, Sun S, Wang K, Zhang M, Li M, Zan Y, Huang Q, Wu S, Zhao W, Xu W, Wu J
Mediators of inflammation 2022;2022:6755407
Mediators of inflammation 2022;2022:6755407
Exploring and Verifying the Mechanism and Targets of Shenqi Pill in the Treatment of Nonalcoholic Steatohepatitis via Network Pharmacology and Experiments.
He B, Chen Z, Nie Y, Luo M, Xu S, Yan J, Chen Z
Journal of immunology research 2022;2022:6588144
Journal of immunology research 2022;2022:6588144
miR-373-3p Regulates the Proliferative and Migratory Properties of Human HTR8 Cells via SLC38A1 Modulation.
Chen L, Wen H, Zhu Y, Wang F, Zhao L, Liang Q, Qu F
Disease markers 2022;2022:6582357
Disease markers 2022;2022:6582357
Integrated Analysis of the Role of Enolase 2 in Clear Cell Renal Cell Carcinoma.
Pan J, Jin Y, Xu X, Wei W, Pan H
Disease markers 2022;2022:6539203
Disease markers 2022;2022:6539203
PFKFB3 Increases IL-1β and TNF-α in Intestinal Epithelial Cells to Promote Tumorigenesis in Colitis-Associated Colorectal Cancer.
Yu H, Dai C, Zhu W, Jin Y, Wang C
Journal of oncology 2022;2022:6367437
Journal of oncology 2022;2022:6367437
Exosomes Derived from SW480-Resistant Colon Cancer Cells Are Promote Angiogenesis via BMP-2/Smad5 Signaling Pathway.
Yang S, Yao L, Wang X, Sun H, Du C, Song C, Fu J, Wu Y, Huang H, Wang C, Wang Y, Xie Y
Applied bionics and biomechanics 2022;2022:6124374
Applied bionics and biomechanics 2022;2022:6124374
Paeoniflorin Regulates NEDD4L/STAT3 Pathway to Induce Ferroptosis in Human Glioma Cells.
Nie XH, Qiu S, Xing Y, Xu J, Lu B, Zhao SF, Li YT, Su ZZ
Journal of oncology 2022;2022:6093216
Journal of oncology 2022;2022:6093216
Huaier Inhibits Gastric Cancer Growth and Hepatic Metastasis by Reducing Syntenin Expression and STAT3 Phosphorylation.
Shi Y, Yuan L, Xu J, Xu H, Wang L, Huang L, Xu Z, Cheng X
Journal of oncology 2022;2022:6065516
Journal of oncology 2022;2022:6065516
Aloin Regulates Matrix Metabolism and Apoptosis in Human Nucleus Pulposus Cells via the TAK1/NF-κB/NLRP3 Signaling Pathway.
Chen T, Li P, Qiu J, Hu W, Li S, Shi H, Qiu X, Huang D, Gao W, Liang A
Stem cells international 2022;2022:5865011
Stem cells international 2022;2022:5865011
Combination of Perindopril Erbumine and Huangqi-Danshen Decoction Protects Against Chronic Kidney Disease via Sirtuin3/Mitochondrial Dynamics Pathway.
Wei X, Wang Y, Weng J, Lao Y, Deng R, Lu J, Yang S, Liu X
Evidence-based complementary and alternative medicine : eCAM 2022;2022:5812105
Evidence-based complementary and alternative medicine : eCAM 2022;2022:5812105
Hepatoprotective Role of 4-Octyl Itaconate in Concanavalin A-Induced Autoimmune Hepatitis.
Yang W, Wang Y, Zhang P, Wang T, Li C, Tong X, Zeng X, Yin Y, Tao K, Li R
Mediators of inflammation 2022;2022:5766434
Mediators of inflammation 2022;2022:5766434
Cigarette Smoke Exposure Increases Glucose-6-phosphate Dehydrogenase, Autophagy, Fibrosis, and Senescence in Kidney Cells In Vitro and In Vivo.
Liu WC, Chuang HC, Chou CL, Lee YH, Chiu YJ, Wang YL, Chiu HW
Oxidative medicine and cellular longevity 2022;2022:5696686
Oxidative medicine and cellular longevity 2022;2022:5696686
IFN-γ induces PD-L1 through p38/JNK/ERK signaling pathways and counteracts the tumor promoting effect mediated by PD-L1 in Glioblastoma.
Jia H, Xie X, Wang L, Wang L, Che F
Computational intelligence and neuroscience 2022;2022:5492602
Computational intelligence and neuroscience 2022;2022:5492602
ASPM Promotes the Progression of Anaplastic Thyroid Carcinomas by Regulating the Wnt/β-Catenin Signaling Pathway.
Jiang L, Zhang S, An N, Chai G, Ye C
International journal of endocrinology 2022;2022:5316102
International journal of endocrinology 2022;2022:5316102
CYP26A1 Is a Novel Cancer Biomarker of Pancreatic Carcinoma: Evidence from Integration Analysis and In Vitro Experiments.
Yu Y, Wang Y, Zou Y, Yu Y
Disease markers 2022;2022:5286820
Disease markers 2022;2022:5286820
Deletion of ACLY Disrupts Histone Acetylation and IL-10 Secretion in Trophoblasts, Which Inhibits M2 Polarization of Macrophages: A Possible Role in Recurrent Spontaneous Abortion.
Chen X, Song QL, Li ZH, Ji R, Wang JY, Ge C, Xiao ZN, Guo DY, Yang J
Oxidative medicine and cellular longevity 2022;2022:5216786
Oxidative medicine and cellular longevity 2022;2022:5216786
LOX and Its Methylation Impact Prognosis of Diseases and Correlate with TAM Infiltration in ESCA.
Wu C, Jiang B, Wu Z, Dong L, Sun K, Wu M
Journal of oncology 2022;2022:5111237
Journal of oncology 2022;2022:5111237
MKK4 Knockdown Plays a Protective Role in Hemorrhagic Shock-Induced Liver Injury through the JNK Pathway.
Yao H, Gao Y, Han J, Wang Y, Cai J, Rui Y, Ge X
Oxidative medicine and cellular longevity 2022;2022:5074153
Oxidative medicine and cellular longevity 2022;2022:5074153
Explore the Mechanism of Astragalus mongholicus Bunge against Nonalcoholic Fatty Liver Disease Based on Network Pharmacology and Experimental Verification.
Fu L, Wu Z, Chu Y, Chen W, Gao L, Mu S, Zhao J
Gastroenterology research and practice 2022;2022:4745042
Gastroenterology research and practice 2022;2022:4745042
Vitamin D3 Supplementation Attenuates Surgery-Induced Neuroinflammation and Cognitive Impairment by Regulating NLRP3 Inflammasome in Mice.
Jiang J, Huang X, Gao X, Yu S
Mediators of inflammation 2022;2022:4696415
Mediators of inflammation 2022;2022:4696415
Antitumor Effect of Si-Jun-Zi Decoction on SGC7901 Gastric Cancer Cells by CMTM2 Activation.
Li X, Chen W, Miao L, Sun H, Gao X, Guo S, Zhang Y, Yang Y, Guo J
Evidence-based complementary and alternative medicine : eCAM 2022;2022:4675815
Evidence-based complementary and alternative medicine : eCAM 2022;2022:4675815
Qizhi Kebitong Formula Ameliorates Streptozocin-Induced Diabetic Osteoporosis through Regulating the PI3K/Akt/NF-κB Pathway.
Tian L, Ding L, Wang G, Guo Y, Zhao Y, Wei Y, Li X, Zhang W, Mi J, Li X, Wang Z, Wang X
BioMed research international 2022;2022:4469766
BioMed research international 2022;2022:4469766
Identification and Validation of Ferroptosis-Related Genes in Sevoflurane-Induced Hippocampal Neurotoxicity.
Miao M, Wang Y, Zeng S, Han Y, Zhu R, Yu P, Yang Y, Fu N, Li N, Sun M, Zhang J
Oxidative medicine and cellular longevity 2022;2022:4435161
Oxidative medicine and cellular longevity 2022;2022:4435161
Schwann Cells Accelerate Osteogenesis via the Mif/CD74/FOXO1 Signaling Pathway In Vitro.
Li JQ, Jiang HJ, Su XY, Feng L, Zhan NZ, Li SS, Chen ZJ, Chang BH, Cheng PZ, Yang L, Pei GX
Stem cells international 2022;2022:4363632
Stem cells international 2022;2022:4363632
4,7-Didehydro-neophysalin B Protects Rat Lung Epithelial Cells against Hydrogen Peroxide-Induced Oxidative Damage through Nrf2-Mediated Signaling Pathway.
Zhong Q, Sun Y, Khan A, Guo J, Wang Z, Sun N, Li H
Oxidative medicine and cellular longevity 2022;2022:4189083
Oxidative medicine and cellular longevity 2022;2022:4189083
The Long Noncoding Transcript HNSCAT1 Activates KRT80 and Triggers Therapeutic Efficacy in Head and Neck Squamous Cell Carcinoma.
Zhao Y, Huang X, Zhang Z, Li H, Zan T
Oxidative medicine and cellular longevity 2022;2022:4156966
Oxidative medicine and cellular longevity 2022;2022:4156966
Acetylation of Atp5f1c Mediates Cardiomyocyte Senescence via Metabolic Dysfunction in Radiation-Induced Heart Damage.
Zeng Z, Xu P, He Y, Yi Y, Liu Z, Cai J, Huang L, Liu A
Oxidative medicine and cellular longevity 2022;2022:4155565
Oxidative medicine and cellular longevity 2022;2022:4155565
CCAAT/Enhancer-Binding Protein Delta Regulates Glioblastoma Survival through Catalase-Mediated Hydrogen Peroxide Clearance.
Lin HY, Lim SW, Hsu TI, Yang WB, Huang CC, Tsai YT, Chang WC, Ko CY
Oxidative medicine and cellular longevity 2022;2022:4081380
Oxidative medicine and cellular longevity 2022;2022:4081380
Eugenol-Preconditioned Mesenchymal Stem Cell-Derived Extracellular Vesicles Promote Antioxidant Capacity of Tendon Stem Cells In Vitro and In Vivo.
Li X, Su Z, Shen K, Wang Q, Xu C, Wang F, Zhang Y, Jiang D
Oxidative medicine and cellular longevity 2022;2022:3945195
Oxidative medicine and cellular longevity 2022;2022:3945195
HIF-1α Regulates the Progression of Cervical Cancer by Targeting YAP/TAZ.
Abudoukerimu A, Hasimu A, Abudoukerimu A, Tuerxuntuoheti G, Huang Y, Wei J, Yu T, Ma H, Yimiti D
Journal of oncology 2022;2022:3814809
Journal of oncology 2022;2022:3814809
Lycopene Improves Bone Quality and Regulates AGE/RAGE/NF-кB Signaling Pathway in High-Fat Diet-Induced Obese Mice.
Xia B, Zhu R, Zhang H, Chen B, Liu Y, Dai X, Ye Z, Zhao D, Mo F, Gao S, Wang XD, Bromme D, Wang L, Wang X, Zhang D
Oxidative medicine and cellular longevity 2022;2022:3697067
Oxidative medicine and cellular longevity 2022;2022:3697067
Isorhamnetin Attenuated the Release of Interleukin-6 from β-Amyloid-Activated Microglia and Mitigated Interleukin-6-Mediated Neurotoxicity.
Wei PC, Lee-Chen GJ, Chen CM, Chen Y, Lo YS, Chang KH
Oxidative medicine and cellular longevity 2022;2022:3652402
Oxidative medicine and cellular longevity 2022;2022:3652402
Metformin Protects against Spinal Cord Injury and Cell Pyroptosis via AMPK/NLRP3 Inflammasome Pathway.
Yuan Y, Fan X, Guo Z, Zhou Z, Gao W
Analytical cellular pathology (Amsterdam) 2022;2022:3634908
Analytical cellular pathology (Amsterdam) 2022;2022:3634908
Extracellular Vesicles of Mesenchymal Stem Cells Are More Effectively Accessed through Polyethylene Glycol-Based Precipitation than by Ultracentrifugation.
Jia L, Li B, Fang C, Liang X, Xie Y, Sun X, Wang W, Zheng L, Wang D
Stem cells international 2022;2022:3577015
Stem cells international 2022;2022:3577015
p16(INK4a) Plays Critical Role in Exacerbating Inflammaging in High Fat Diet Induced Skin.
Liang Y, Gu T, Peng S, Lin Y, Liu J, Wang X, Huang X, Zhang X, Zhu J, Zhao L, Fan C, Wang G, Gu X, Lin J
Oxidative medicine and cellular longevity 2022;2022:3415528
Oxidative medicine and cellular longevity 2022;2022:3415528
FBXW7 Reduces the Cancer Stem Cell-Like Properties of Hepatocellular Carcinoma by Regulating the Ubiquitination and Degradation of ACTL6A.
Wang X, Li Y, Li Y, Liu P, Liu S, Pan Y
Stem cells international 2022;2022:3242482
Stem cells international 2022;2022:3242482
Biochanin A Suppresses Tumor Progression and PD-L1 Expression via Inhibiting ZEB1 Expression in Colorectal Cancer.
Xu J, Yang X, Pan J, Fan H, Mei J, Hua D
Journal of oncology 2022;2022:3224373
Journal of oncology 2022;2022:3224373
Cyclic Polypeptide D7 Protects Bone Marrow Mesenchymal Cells and Promotes Chondrogenesis during Osteonecrosis of the Femoral Head via Growth Differentiation Factor 15-Mediated Redox Signaling.
Chen J, Cui Z, Wang Y, Lyu L, Feng C, Feng D, Cheng Y, Li Z, Sun S
Oxidative medicine and cellular longevity 2022;2022:3182368
Oxidative medicine and cellular longevity 2022;2022:3182368
Nicandra physalodes Extract Exerts Antiaging Effects in Multiple Models and Extends the Lifespan of Caenorhabditis elegans via DAF-16 and HSF-1.
Wang J, Huang Y, Shi K, Bao L, Xiao C, Sun T, Mao Z, Feng J, Hu Z, Guo Z, Li J, Jiang B, Liu W, Li J
Oxidative medicine and cellular longevity 2022;2022:3151071
Oxidative medicine and cellular longevity 2022;2022:3151071
Study on the Potential Mechanism of Semen Strychni against Myasthenia Gravis Based on Network Pharmacology and Molecular Docking with Experimental Verification.
Fang P, Yu C, Liu J, Deng G, Zhang M
Evidence-based complementary and alternative medicine : eCAM 2022;2022:3056802
Evidence-based complementary and alternative medicine : eCAM 2022;2022:3056802
Rapamycin Attenuates Anxiety and Depressive Behavior Induced by Helicobacter pylori in Association with Reduced Circulating Levels of Ghrelin.
Tian J, Wang Z, Ren Y, Jiang Y, Zhao Y, Li M, Zhang Z
Neural plasticity 2022;2022:2847672
Neural plasticity 2022;2022:2847672
Baicalin Ameliorates DSS-Induced Colitis by Protecting Goblet Cells through Activating NLRP6 Inflammasomes.
Li Y, Hu J, Cheng C, Xu F, Au R, Zhu L, Shen H
Evidence-based complementary and alternative medicine : eCAM 2022;2022:2818136
Evidence-based complementary and alternative medicine : eCAM 2022;2022:2818136
Hinokitiol Protects Cardiomyocyte from Oxidative Damage by Inhibiting GSK3β-Mediated Autophagy.
Xiao H, Liang S, Cai Q, Liu J, Jin L, Yang Z, Chen X
Oxidative medicine and cellular longevity 2022;2022:2700000
Oxidative medicine and cellular longevity 2022;2022:2700000
(-)-Epicatechin Reduces Neuroinflammation, Protects Mitochondria Function, and Prevents Cognitive Impairment in Sepsis-Associated Encephalopathy.
Ling J, Wu Y, Zou X, Chang Y, Li G, Fang M
Oxidative medicine and cellular longevity 2022;2022:2657713
Oxidative medicine and cellular longevity 2022;2022:2657713
Streptococcus lutetiensis Induces Autophagy via Oxidative Stress in Bovine Mammary Epithelial Cells.
Chen P, Yang J, Wu N, Han B, Kastelic JP, Gao J
Oxidative medicine and cellular longevity 2022;2022:2549772
Oxidative medicine and cellular longevity 2022;2022:2549772
GSDME Increases Chemotherapeutic Drug Sensitivity by Inducing Pyroptosis in Retinoblastoma Cells.
Li F, Xia Q, Ren L, Nie Y, Ren H, Guo X, Yu J, Xing Y, Chen Z
Oxidative medicine and cellular longevity 2022;2022:2371807
Oxidative medicine and cellular longevity 2022;2022:2371807
Stage-Dependent Regulation of Dental Pulp Stem Cell Odontogenic Differentiation by Transforming Growth Factor-β1.
Bai Y, Liu X, Li J, Wang Z, Guo Q, Xiao M, Cooper PR, Yu Q, He W
Stem cells international 2022;2022:2361376
Stem cells international 2022;2022:2361376
Exercise and Metformin Intervention Prevents Lipotoxicity-Induced Hepatocyte Apoptosis by Alleviating Oxidative and ER Stress and Activating the AMPK/Nrf2/HO-1 Signaling Pathway in db/db Mice.
Zhang Y, Liu Y, Liu X, Yuan X, Xiang M, Liu J, Zhang L, Zhu S, Lu J, Tang Q, Cheng S
Oxidative medicine and cellular longevity 2022;2022:2297268
Oxidative medicine and cellular longevity 2022;2022:2297268
Enamel Matrix Derivative Enhances the Odontoblastic Differentiation of Dental Pulp Stem Cells via Activating MAPK Signaling Pathways.
Zhang B, Xiao M, Cheng X, Bai Y, Chen H, Yu Q, Qiu L
Stem cells international 2022;2022:2236250
Stem cells international 2022;2022:2236250
Idol Depletion Protects against Spontaneous Atherosclerosis in a Hamster Model of Familial Hypercholesterolemia.
Liang C, Wang X, Peng K, Lai P, Liu Z, Ma J, Chen X, Liu G, Zheng M, Wang Y, Yang H, Liu G, Xian X, Gao M
Oxidative medicine and cellular longevity 2022;2022:1889632
Oxidative medicine and cellular longevity 2022;2022:1889632
Honokiol Ameliorates DSS-Induced Mouse Colitis by Inhibiting Inflammation and Oxidative Stress and Improving the Intestinal Barrier.
Wang L, Wang J
Oxidative medicine and cellular longevity 2022;2022:1755608
Oxidative medicine and cellular longevity 2022;2022:1755608
Sirt1 Mediates Vitamin D Deficiency-Driven Gluconeogenesis in the Liver via mTorc2/Akt Signaling.
Yuan Q, Zhang R, Sun M, Guo X, Yang J, Bian W, Xie C, Miao D, Mao L
Journal of diabetes research 2022;2022:1755563
Journal of diabetes research 2022;2022:1755563
DRDB: A Machine Learning Platform to Predict Chemical-Protein Interactions towards Diabetic Retinopathy.
Wei Y, Zhang R, Li X, Li Z, Guo K, Li S, Yan L, Zhao Q, Qu B, Wang W, Zhou S, Sun H, Lin J, Hu Y
Oxidative medicine and cellular longevity 2022;2022:1718353
Oxidative medicine and cellular longevity 2022;2022:1718353
Lignans from Mosla scabra Ameliorated Influenza A Virus-Induced Pneumonia via Inhibiting Macrophage Activation.
Cai W, Wu LR, Zhang SL
Evidence-based complementary and alternative medicine : eCAM 2022;2022:1688826
Evidence-based complementary and alternative medicine : eCAM 2022;2022:1688826
Aberrant Expression of Mitochondrial SAM Transporter SLC25A26 Impairs Oocyte Maturation and Early Development in Mice.
Cheng GP, Guo SM, Yin Y, Li YY, He X, Zhou LQ
Oxidative medicine and cellular longevity 2022;2022:1681623
Oxidative medicine and cellular longevity 2022;2022:1681623
Tangshenning Attenuates High Glucose-Induced Podocyte Injury via Restoring Autophagy Activity through Inhibiting mTORC1 Activation.
Xu J, Shan X, Chen C, Gao Y, Zou D, Wang X, Wang T, Shi Y
Journal of diabetes research 2022;2022:1610416
Journal of diabetes research 2022;2022:1610416
Upregulated LINC00922 Promotes Epithelial-Mesenchymal Transition and Indicates a Dismal Prognosis in Gastric Cancer.
Chen X, Hu L, Mao X, Chen H, She Y, Chi H, Zeng H, Guo L, Han Y
Journal of oncology 2022;2022:1608936
Journal of oncology 2022;2022:1608936
Qufeng Xuanbi Formula Ameliorates Airway Remodeling in Asthmatic Mice by Suppressing Airway Smooth Muscle Cell Proliferation through MEK/ERK Signaling Pathway.
Wang B, Tang L, Shi S, Yang Y, Sun X, Zhang X, Liu C, Liu L
Evidence-based complementary and alternative medicine : eCAM 2022;2022:1525110
Evidence-based complementary and alternative medicine : eCAM 2022;2022:1525110
Repeated Yueju, But Not Fluoxetine, Induced Sustained Antidepressant Activity in a Mouse Model of Chronic Learned Helplessness: Involvement of CaMKII Signaling in the Hippocampus.
Zou Z, Huang J, Yang Q, Zhang Y, Xu B, Wang P, Chen G
Evidence-based complementary and alternative medicine : eCAM 2022;2022:1442578
Evidence-based complementary and alternative medicine : eCAM 2022;2022:1442578
Hydrogen Sulfide Ameliorated High Choline-Induced Cardiac Dysfunction by Inhibiting cGAS-STING-NLRP3 Inflammasome Pathway.
Bai L, Dai J, Xia Y, He K, Xue H, Guo Q, Tian D, Xiao L, Zhang X, Teng X, Wu Y, Jin S
Oxidative medicine and cellular longevity 2022;2022:1392896
Oxidative medicine and cellular longevity 2022;2022:1392896
Characterization of Acetylation of Histone H3 at Lysine 9 in the Trigeminal Ganglion of a Rat Trigeminal Neuralgia Model.
Wei W, Liu Y, Qiu Y, Chen M, Wang Y, Han Z, Chai Y
Oxidative medicine and cellular longevity 2022;2022:1300387
Oxidative medicine and cellular longevity 2022;2022:1300387
Protective Effects of Vitamin C against Neomycin-Induced Apoptosis in HEI-OC1 Auditory Cell.
Gong L, Chen B, Chen J, Li Y
Neural plasticity 2022;2022:1298692
Neural plasticity 2022;2022:1298692
Inhibition of GSDMD Activates Poly(ADP-ribosyl)ation and Promotes Myocardial Ischemia-Reperfusion Injury.
Zhang ZH, Zhang ZG, Chen MW, Yang Y, Li RJ, Xu JJ, Yang C, Li YY, Chen HW, Liu SX, Li YL, Luo P, Liu YJ, Chen WB, Shan ZG, Huang ZR
Oxidative medicine and cellular longevity 2022;2022:1115749
Oxidative medicine and cellular longevity 2022;2022:1115749
Honokiol Provides Cardioprotection from Myocardial Ischemia/Reperfusion Injury (MI/RI) by Inhibiting Mitochondrial Apoptosis via the PI3K/AKT Signaling Pathway.
Lv L, Kong Q, Li Z, Zhang Y, Chen B, Lv L, Zhang Y
Cardiovascular therapeutics 2022;2022:1001692
Cardiovascular therapeutics 2022;2022:1001692
Mechanism of Abelmoschus manihot L. in the Treatment of Contrast-Induced Nephropathy on the Basis of Network Pharmacology Analysis.
Xu Z, Qian L, Niu R, Wang Y, Yang Y, Liu C, Lin X
Frontiers in nephrology 2022;2:834513
Frontiers in nephrology 2022;2:834513
LIM Mineralization Protein-1 Enhances the Committed Differentiation of Dental Pulp Stem Cells through the ERK1/2 and p38 MAPK Pathways and BMP Signaling.
Mu R, Chen B, Bi B, Yu H, Liu J, Li J, He M, Rong L, Liu B, Liu K, Zhu L, Shi X, Shuai Y, Jin L
International journal of medical sciences 2022;19(8):1307-1319
International journal of medical sciences 2022;19(8):1307-1319
Loss-of-function Mutations K11E or E271K Lead to Novel Tumor Suppression, Implicate Nucleolar Helicase DDX24 Oncogenicity.
Li X, Chen X, Gao J, Xian J, Li Z, Bi L, Yang M, Yang S, Jin H, Shan H
International journal of medical sciences 2022;19(3):596-608
International journal of medical sciences 2022;19(3):596-608
Egr1 confers protection against acetaminophen‑induced hepatotoxicity via transcriptional upregulating of Acaa2.
Lei X, Xu Q, Li C, Niu B, Ming Y, Li J, Tang Y, Li X, Tang J, Wu J, Ju Y, Yao L, Wang B, Miao Q, Zhong W, Zhi Y, Xu L, Li C, Li X, Mao Y
International journal of biological sciences 2022;18(9):3800-3817
International journal of biological sciences 2022;18(9):3800-3817
NUF2 Drives Clear Cell Renal Cell Carcinoma by Activating HMGA2 Transcription through KDM2A-mediated H3K36me2 Demethylation.
Lin J, Chen X, Yu H, Min S, Chen Y, Li Z, Xie X
International journal of biological sciences 2022;18(9):3621-3635
International journal of biological sciences 2022;18(9):3621-3635
UBE2S as a novel ubiquitinated regulator of p16 and β-catenin to promote bone metastasis of prostate cancer.
Peng S, Chen X, Huang C, Yang C, Situ M, Zhou Q, Ling Y, Huang H, Huang M, Zhang Y, Cheng L, Zhang Q, Guo Z, Lai Y, Huang J
International journal of biological sciences 2022;18(8):3528-3543
International journal of biological sciences 2022;18(8):3528-3543
KLF4 Alleviates Hypertrophic Scar Fibrosis by Directly Activating BMP4 Transcription.
Wang J, Zhao M, Zhang H, Yang F, Luo L, Shen K, Wang X, Li Y, Zhang J, Zhang J, Wang K, Li J, Wang Y, Yang Y, Hu D
International journal of biological sciences 2022;18(8):3324-3336
International journal of biological sciences 2022;18(8):3324-3336
HERC3 directly targets RPL23A for ubiquitination degradation and further regulates Colorectal Cancer proliferation and the cell cycle.
Zhang Z, Wu Q, Fang M, Liu Y, Jiang J, Feng Q, Hu R, Xu J
International journal of biological sciences 2022;18(8):3282-3297
International journal of biological sciences 2022;18(8):3282-3297
The GR-gp78 Pathway is involved in Hepatic Lipid Accumulation Induced by Overexpression of 11β-HSD1.
Hu M, Han T, Pan Q, Ni D, Gao F, Wang L, Ren H, Zhang X, Jiao H, Wang Y, Dai D, Man Y, Tang W, Sun Y, Li W, Li J, Li G
International journal of biological sciences 2022;18(8):3107-3121
International journal of biological sciences 2022;18(8):3107-3121
Photobiomodulation Drives MiR-136-5p Expression to Promote Injury Repair after Myocardial Infarction.
Gao X, Li H, Zhang W, Wang X, Sun H, Cao Y, Zhao Y, Ji H, Yang F, Ma W, Liu Y, Yang B, Cai B
International journal of biological sciences 2022;18(7):2980-2993
International journal of biological sciences 2022;18(7):2980-2993
Downregulation of lncRNA APCDD1L-AS1 due to DNA hypermethylation and loss of VHL protein expression promotes the progression of clear cell renal cell carcinoma.
Yang W, Zhou J, Zhang Z, Zhang K, Xu Y, Li L, Cai L, Gong Y, Gong K
International journal of biological sciences 2022;18(6):2583-2596
International journal of biological sciences 2022;18(6):2583-2596
TDG suppresses the migration and invasion of human colon cancer cells via the DNMT3A/TIMP2 axis.
Miao J, Zhao C, Tang K, Xiong X, Wu F, Xue W, Duan B, Zhang H, Jing X, Li W, Sun Y, Hou N, Huang C
International journal of biological sciences 2022;18(6):2527-2539
International journal of biological sciences 2022;18(6):2527-2539
Claudin-10 overexpression suppresses human clear cell renal cell carcinoma growth and metastasis by regulating ATP5O and causing mitochondrial dysfunction.
Yang W, Zhang K, Zhang Z, Zhou J, Li L, Xu Y, Qiu J, Cai L, Gong Y, Gong K
International journal of biological sciences 2022;18(6):2329-2344
International journal of biological sciences 2022;18(6):2329-2344
Melatonin reverses tumor necrosis factor-alpha-induced metabolic disturbance of human nucleus pulposus cells via MTNR1B/Gαi2/YAP signaling.
Qiu X, Liang T, Wu Z, Zhu Y, Gao W, Gao B, Qiu J, Wang X, Chen T, Deng Z, Li P, Chen Y, Zhou H, Peng Y, Xu C, Su P, Liang A, Huang D
International journal of biological sciences 2022;18(5):2202-2219
International journal of biological sciences 2022;18(5):2202-2219
The RNF26/CBX7 axis modulates the TNF pathway to promote cell proliferation and regulate sensitivity to TKIs in ccRCC.
Liu W, Wang H, Jian C, Li W, Ye K, Ren J, Zhu L, Wang Y, Jin X, Yi L
International journal of biological sciences 2022;18(5):2132-2145
International journal of biological sciences 2022;18(5):2132-2145
HB-EGF induces mitochondrial dysfunction via estrogen hypersecretion in granulosa cells dependent on cAMP-PKA-JNK/ERK-Ca(2+)-FOXO1 pathway.
Huang JC, Duan CC, Jin S, Sheng CB, Wang YS, Yue ZP, Guo B
International journal of biological sciences 2022;18(5):2047-2059
International journal of biological sciences 2022;18(5):2047-2059
Atractylenolide III ameliorates Non-Alcoholic Fatty Liver Disease by activating Hepatic Adiponectin Receptor 1-Mediated AMPK Pathway.
Li Q, Tan JX, He Y, Bai F, Li SW, Hou YW, Ji LS, Gao YT, Zhang X, Zhou ZH, Yu Z, Fang M, Gao YQ, Li M
International journal of biological sciences 2022;18(4):1594-1611
International journal of biological sciences 2022;18(4):1594-1611
OTUD1 stabilizes PTEN to inhibit the PI3K/AKT and TNF-alpha/NF-kappaB signaling pathways and sensitize ccRCC to TKIs.
Liu W, Yan B, Yu H, Ren J, Peng M, Zhu L, Wang Y, Jin X, Yi L
International journal of biological sciences 2022;18(4):1401-1414
International journal of biological sciences 2022;18(4):1401-1414
Hypoxic pancreatic cancer derived exosomal miR-30b-5p promotes tumor angiogenesis by inhibiting GJA1 expression.
Chen K, Wang Q, Liu X, Wang F, Yang Y, Tian X
International journal of biological sciences 2022;18(3):1220-1237
International journal of biological sciences 2022;18(3):1220-1237
As a Novel Tumor Suppressor, LHPP Promotes Apoptosis by Inhibiting the PI3K/AKT Signaling Pathway in Oral Squamous Cell Carcinoma.
Liu S, Gao W, Lu Y, Zhou Q, Su R, Hasegawa T, Du J, Li M
International journal of biological sciences 2022;18(2):491-506
International journal of biological sciences 2022;18(2):491-506
ID09, A Newly-Designed Tubulin Inhibitor, Regulating the Proliferation, Migration, EMT Process and Apoptosis of Oral Squamous Cell Carcinoma.
Feng Q, Yang P, Wang H, Li C, Hasegawa T, Liu Z, Li M
International journal of biological sciences 2022;18(2):473-490
International journal of biological sciences 2022;18(2):473-490
P2RY13 Exacerbates Intestinal Inflammation by Damaging the Intestinal Mucosal Barrier via Activating IL-6/STAT3 Pathway.
Wu X, Wei S, Chen M, Li J, Wei Y, Zhang J, Dong W
International journal of biological sciences 2022;18(13):5056-5069
International journal of biological sciences 2022;18(13):5056-5069
RASAL2 mediated the enhancement of YAP1/TIAM1 signaling promotes malignant phenotypes of pancreatic ductal adenocarcinoma.
Yue Y, Wu K, Qian W, Zhu Z, Zhang S, Zhang W, Zhang W, Wu S, Li L, Wu Z, Ma Q, Xie K, Wang Z
International journal of biological sciences 2022;18(10):4245-4259
International journal of biological sciences 2022;18(10):4245-4259
Nicotine has no significant cytoprotective activity against SARS-CoV-2 infection.
Zheng F, Lian E, Ramirez G, McAlister C, Zhou S, Zhang W, Liu C, Perera R, Zhan CG
PloS one 2022;17(8):e0272941
PloS one 2022;17(8):e0272941
Aspirin mediates protection from diabetic kidney disease by inducing ferroptosis inhibition.
Wu Z, Li D, Tian D, Liu X, Wu Z
PloS one 2022;17(12):e0279010
PloS one 2022;17(12):e0279010
Cystathionine γ-lyase and hydrogen sulfide modulates glucose transporter Glut1 expression via NF-κB and PI3k/Akt in macrophages during inflammation.
Cornwell A, Fedotova S, Cowan S, Badiei A
PloS one 2022;17(12):e0278910
PloS one 2022;17(12):e0278910
AMBRA1 attenuates the proliferation of uveal melanoma cells.
Zhao B, Yang Y, Cun B, Chen P
Open medicine (Warsaw, Poland) 2022;17(1):1-14
Open medicine (Warsaw, Poland) 2022;17(1):1-14
B16 Membrane-Coated Vesicles for Combined Photodynamic Therapy and Immunotherapy Shift Immune Microenvironment of Melanoma.
Wang Y, Zhao Z, Liu C, Hao M, Kong C, Zhao X, Gao Y, Zhang Y, Cui W, Zhang C, Jiang J
International journal of nanomedicine 2022;17:855-868
International journal of nanomedicine 2022;17:855-868
Decreased tubulin-binding cofactor B was involved in the formation disorder of nascent astrocyte processes by regulating microtubule plus-end growth through binding with end-binding proteins 1 and 3 after chronic alcohol exposure.
Zheng Y, Yang M, Chen X, Zhang G, Wan S, Zhang B, Huo J, Liu H
Frontiers in cellular neuroscience 2022;16:989945
Frontiers in cellular neuroscience 2022;16:989945
Focused Ultrasound Promotes the Delivery of Gastrodin and Enhances the Protective Effect on Dopaminergic Neurons in a Mouse Model of Parkinson's Disease.
Wang Y, Luo K, Li J, Liao Y, Liao C, Chen WS, Chen M, Ao L
Frontiers in cellular neuroscience 2022;16:884788
Frontiers in cellular neuroscience 2022;16:884788
CAMTA1 gene affects the ischemia-reperfusion injury by regulating CCND1.
Liu Y, Shang G, Zhang X, Liu F, Zhang C, Li Z, Jia J, Xu Y, Zhang Z, Yang S, Zhou B, Luan Y, Huang Y, Peng Y, Han T, He Y, Zheng H
Frontiers in cellular neuroscience 2022;16:868291
Frontiers in cellular neuroscience 2022;16:868291
Predictors of prodromal Parkinson's disease in young adult Pink1-/- rats.
Lechner SA, Welsch JM, Pahapill NK, Kaldenberg TAR, Regenbaum A, Kelm-Nelson CA
Frontiers in behavioral neuroscience 2022;16:867958
Frontiers in behavioral neuroscience 2022;16:867958
Rapamycin Improved Retinal Function and Morphology in a Mouse Model of Retinal Degeneration.
Zhao M, Lv H, Yang N, Peng GH
Frontiers in neuroscience 2022;16:846584
Frontiers in neuroscience 2022;16:846584
Laparotomy-Induced Peripheral Inflammation Activates NR2B Receptors on the Brain Mast Cells and Results in Neuroinflammation in a Vagus Nerve-Dependent Manner.
Yang J, Dong HQ, Liu YH, Ji MH, Zhang X, Dai HY, Sun ZC, Liu L, Zhou J, Sha HH, Qian YN, Li QG, Yao H, Li NN
Frontiers in cellular neuroscience 2022;16:771156
Frontiers in cellular neuroscience 2022;16:771156
Inhibition of CXCR4 in Spinal Cord and DRG with AMD3100 Attenuates Colon-Bladder Cross-Organ Sensitization.
Zhang H, Dong X, Yang Z, Zhao J, Lu Q, Zhu J, Li L, Yi S, Xu J
Drug design, development and therapy 2022;16:67-81
Drug design, development and therapy 2022;16:67-81
Keloid Patient Plasma-Derived Exosomal hsa_circ_0020792 Promotes Normal Skin Fibroblasts Proliferation, Migration, and Fibrogenesis via Modulating miR-193a-5p and Activating TGF-β1/Smad2/3 Signaling.
Hu H, Mao G, Zheng J, Guo F
Drug design, development and therapy 2022;16:4223-4234
Drug design, development and therapy 2022;16:4223-4234
Madecassic Acid Ameliorates the Progression of Osteoarthritis: An in vitro and in vivo Study.
Fu X, He S, Wang L, Xue Y, Qiao S, An J, Xia T
Drug design, development and therapy 2022;16:3793-3804
Drug design, development and therapy 2022;16:3793-3804
Network Pharmacology and Experimental Verification to Explore the Potential Mechanism of Yin-Huo-Tang for Lung Adenocarcinoma Recurrence.
Liu D, Lin S, Li Y, Zhou T, Hu K, Li Q
Drug design, development and therapy 2022;16:375-395
Drug design, development and therapy 2022;16:375-395
Sinomenine Inhibits Orthodontic Tooth Movement and Root Resorption in Rats and Enhances Osteogenic Differentiation of PDLSCs.
Li H, Li Y, Zou J, Yang Y, Han R, Zhang J
Drug design, development and therapy 2022;16:2949-2965
Drug design, development and therapy 2022;16:2949-2965
Exploration of the Effect and Potential Mechanism of Echinacoside Against Endometrial Cancer Based on Network Pharmacology and in vitro Experimental Verification.
Shu W, Wang Z, Zhao R, Shi R, Zhang J, Zhang W, Wang H
Drug design, development and therapy 2022;16:1847-1863
Drug design, development and therapy 2022;16:1847-1863
Inhibitory effects of luteolin on TLR3-mediated inflammation caused by TAK/NF-κB signaling in human corneal fibroblasts.
Guo ZH, Liu PP, Wang H, Yang XX, Yang CC, Zheng H, Tang D, Liu Y
International journal of ophthalmology 2022;15(3):371-379
International journal of ophthalmology 2022;15(3):371-379
Nedd4-2 Haploinsufficiency in Mice Impairs the Ubiquitination of Rer1 and Increases the Susceptibility to Endoplasmic Reticulum Stress and Seizures.
Liu X, Zhang L, Zhang H, Liang X, Zhang B, Tu J, Zhao Y
Frontiers in molecular neuroscience 2022;15:919718
Frontiers in molecular neuroscience 2022;15:919718
Excitatory and Inhibitory Synaptic Imbalance Caused by Brain-Derived Neurotrophic Factor Deficits During Development in a Valproic Acid Mouse Model of Autism.
Qi C, Chen A, Mao H, Hu E, Ge J, Ma G, Ren K, Xue Q, Wang W, Wu S
Frontiers in molecular neuroscience 2022;15:860275
Frontiers in molecular neuroscience 2022;15:860275
The cAMP Response Element- Binding Protein/Brain-Derived Neurotrophic Factor Pathway in Anterior Cingulate Cortex Regulates Neuropathic Pain and Anxiodepression Like Behaviors in Rats.
Wen J, Xu Y, Yu Z, Zhou Y, Wang W, Yang J, Wang Y, Bai Q, Li Z
Frontiers in molecular neuroscience 2022;15:831151
Frontiers in molecular neuroscience 2022;15:831151
The Ameliorative Effect of JNK Inhibitor D-JNKI-1 on Neomycin-Induced Apoptosis in HEI-OC1 Cells.
Zhao J, Liu H, Huang Z, Yang R, Gong L
Frontiers in molecular neuroscience 2022;15:824762
Frontiers in molecular neuroscience 2022;15:824762
Effect of Tensile Frequency on the Osteogenic Differentiation of Periodontal Ligament Stem Cells.
Wang W, Wang M, Guo X, Zhao Y, Ahmed MMS, Qi H, Chen X
International journal of general medicine 2022;15:5957-5971
International journal of general medicine 2022;15:5957-5971
LPS-Induced Activation of the cGAS-STING Pathway is Regulated by Mitochondrial Dysfunction and Mitochondrial DNA Leakage in Endometritis.
Li MZ, Wen XY, Liu XQ, Wang YQ, Yan L
Journal of inflammation research 2022;15:5707-5720
Journal of inflammation research 2022;15:5707-5720
MULT1-Encoding DNA Alleviates Schistosomiasis-Associated Hepatic Fibrosis via Modulating Cellular Immune Response.
Yang L, Sun L, Cao Y, Wang Q, Song A, Zhu R, Liu W, Lu S
Journal of inflammation research 2022;15:4027-4045
Journal of inflammation research 2022;15:4027-4045
TRPV1 and GABA(B1) in the Cerebrospinal Fluid-Contacting Nucleus are Jointly Involved in Chronic Inflammatory Pain in Rats.
Xu LL, Yan Y, Yuan YM, Li Y, Jiang J, Zhang LC
Journal of pain research 2022;15:3931-3939
Journal of pain research 2022;15:3931-3939
The Role of Bone Morphogenetic Protein 4 in Microglial Polarization in the Process of Neuropathic Pain.
Liu C, Sun Q, Xu J, Shen W, Li H, Yang L
Journal of inflammation research 2022;15:2803-2817
Journal of inflammation research 2022;15:2803-2817
MAF bZIP Transcription Factor B (MAFB) Protected Against Ovalbumin-Induced Allergic Rhinitis via the Alleviation of Inflammation by Restoring the T Helper (Th) 1/Th2/Th17 Imbalance and Epithelial Barrier Dysfunction.
Sun Y, Liu T, Bai W
Journal of asthma and allergy 2022;15:267-280
Journal of asthma and allergy 2022;15:267-280
Protective Effect of Crocin on Immune Checkpoint Inhibitors-Related Myocarditis Through Inhibiting NLRP3 Mediated Pyroptosis in Cardiomyocytes via NF-κB Pathway.
Zhang H, Lin J, Shen Y, Pan J, Wang C, Cheng L
Journal of inflammation research 2022;15:1653-1666
Journal of inflammation research 2022;15:1653-1666
The Involvement of Endothelin Pathway in Chronic Psychological Stress-Induced Bladder Hyperalgesia Through Capsaicin-Sensitive C-Fiber Afferents.
Qin C, Wang Y, Li S, Tang Y, Gao Y
Journal of inflammation research 2022;15:1209-1226
Journal of inflammation research 2022;15:1209-1226
Galectin-9/Tim-3 pathway mediates dopaminergic neurodegeneration in MPTP-induced mouse model of Parkinson's disease.
Peng Q, Zhang G, Guo X, Dai L, Xiong M, Zhang Z, Chen L, Zhang Z
Frontiers in molecular neuroscience 2022;15:1046992
Frontiers in molecular neuroscience 2022;15:1046992
Down-regulation of NOTCH1 and PKM2 can inhibit the growth and metastasis of colorectal cancer cells.
Wang J, Sun M, Ma R, Wang G, Li W, Yang B, Yang Y
American journal of translational research 2022;14(8):5455-5465
American journal of translational research 2022;14(8):5455-5465
Wnt5a protects motor neurons in amyotrophic lateral sclerosis by regulating the Wnt/Ca(2+) signaling pathway.
Liu J, Zhou F, Chen Y, Guan Y, Meng F, Zhao Z, Wang X, Gao X, Jiang X, Zhang H, Wang Q, Zhou S, Wang X
American journal of translational research 2022;14(8):5343-5362
American journal of translational research 2022;14(8):5343-5362
Senomorphic agent pterostilbene ameliorates osteoarthritis through the PI3K/AKT/NF-κB axis: an in vitro and in vivo study.
Wang Y, Zhao H, Jia S, Wang Q, Yao W, Yang Y, Bai L
American journal of translational research 2022;14(8):5243-5262
American journal of translational research 2022;14(8):5243-5262
Stachydrine hydrochloride ameliorates cardiac hypertrophy through CaMKII/HDAC4/MEF2C signal pathway.
Li XQ, Lu S, Xia L, Shan XL, Zhao WX, Chen HH, Zhang C, Guo W, Xu M, Lu R, Zhao P
American journal of translational research 2022;14(6):3840-3853
American journal of translational research 2022;14(6):3840-3853
LncRNA PCAT7 promotes non-small cell lung cancer progression by activating miR-486-5p/CDK4 axis-mediated cell cycle.
Geng W, Qiu M, Zhang D, Li P, Sun G, Zhou X
American journal of translational research 2022;14(5):3003-3016
American journal of translational research 2022;14(5):3003-3016
A novel curcumin oil solution can better alleviate the motor activity defects and neuropathological damage of a Parkinson's disease mouse model.
Geng X, Zhang H, Hu M, Liu X, Han M, Xie J, Li Z, Zhao F, Liu W, Wei S
Frontiers in aging neuroscience 2022;14:984895
Frontiers in aging neuroscience 2022;14:984895
Huangqin Decoction Exerts Beneficial Effects on Rotenone-Induced Rat Model of Parkinson's Disease by Improving Mitochondrial Dysfunction and Alleviating Metabolic Abnormality of Mitochondria.
Gao L, Cao M, Du GH, Qin XM
Frontiers in aging neuroscience 2022;14:911924
Frontiers in aging neuroscience 2022;14:911924
Growth Differentiation Factor 15 Regulates Oxidative Stress-Dependent Ferroptosis Post Spinal Cord Injury by Stabilizing the p62-Keap1-Nrf2 Signaling Pathway.
Xia M, Zhang Q, Zhang Y, Li R, Zhao T, Chen L, Liu Q, Zheng S, Li H, Qian Z, Yang L
Frontiers in aging neuroscience 2022;14:905115
Frontiers in aging neuroscience 2022;14:905115
Methyltransferase-Like 3 Rescues the Amyloid-beta protein-Induced Reduction of Activity-Regulated Cytoskeleton Associated Protein Expression via YTHDF1-Dependent N6-Methyladenosine Modification.
Xu C, Huang H, Zhang M, Zhang P, Li Z, Liu X, Fang M
Frontiers in aging neuroscience 2022;14:890134
Frontiers in aging neuroscience 2022;14:890134
Impact prediction of translocation of the mitochondrial outer membrane 70 as biomarker in Alzheimer's disease.
Cao X, Chen Y, Sang X, Xu S, Xie Z, Zhu Z, Wang P, Bi J, Xu L
Frontiers in aging neuroscience 2022;14:1013943
Frontiers in aging neuroscience 2022;14:1013943
Inducing Synergistic DNA Damage by TRIP13 and PARP1 Inhibitors Provides a Potential Treatment for Hepatocellular Carcinoma.
Xu H, Ma Z, Mo X, Chen X, Xu F, Wu F, Chen H, Zhou G, Xia H, Zhang C
Journal of Cancer 2022;13(7):2226-2237
Journal of Cancer 2022;13(7):2226-2237
ASF1b is a novel prognostic predictor associated with cell cycle signaling pathway in gastric cancer.
Chen C, Bao H, Lin W, Chen X, Huang Y, Wang H, Yang Y, Liu J, Lv X, Teng L
Journal of Cancer 2022;13(6):1985-2000
Journal of Cancer 2022;13(6):1985-2000
Targeting HNRNPM Inhibits Cancer Stemness and Enhances Antitumor Immunity in Wnt-activated Hepatocellular Carcinoma.
Zhu GQ, Wang Y, Wang B, Liu WR, Dong SS, Chen EB, Cai JL, Wan JL, Du JX, Song LN, Chen SP, Yu L, Zhou ZJ, Wang Z, Zhou J, Shi YH, Fan J, Dai Z
Cellular and molecular gastroenterology and hepatology 2022;13(5):1413-1447
Cellular and molecular gastroenterology and hepatology 2022;13(5):1413-1447
A Novel Mouse Model Harboring Hepatitis B Virus Covalently Closed Circular DNA.
Xu Z, Zhao L, Zhong Y, Zhu C, Zhao K, Teng Y, Cheng X, Chen Q, Xia Y
Cellular and molecular gastroenterology and hepatology 2022;13(4):1001-1017
Cellular and molecular gastroenterology and hepatology 2022;13(4):1001-1017
LHPP suppresses gastric cancer progression via the PI3K/AKT/mTOR signaling pathway.
Wang D, Li J, Li W
Journal of Cancer 2022;13(14):3584-3592
Journal of Cancer 2022;13(14):3584-3592
The lncRNA CRNDE is regulated by E2F6 and sensitizes gastric cancer cells to chemotherapy by inhibiting autophagy.
Zhang F, Chen Q, Chen P, Liu C, Wang H, Zhao L
Journal of Cancer 2022;13(10):3061-3072
Journal of Cancer 2022;13(10):3061-3072
Down-regulation of MSMO1 promotes the development and progression of pancreatic cancer.
Cao R, Zhang Z, Tian C, Sheng W, Dong Q, Dong M
Journal of Cancer 2022;13(10):3013-3021
Journal of Cancer 2022;13(10):3013-3021
Trichodimerol inhibits inflammation through suppression of the nuclear transcription factor-kappaB/NOD-like receptor thermal protein domain associated protein 3 signaling pathway.
Huo XY, Lei LR, Guo WX, Hu YJ, Kuang QX, Liu MD, Peng W, Dai YF, Wang D, Gu YC, Guo DL, Deng Y
Frontiers in microbiology 2022;13:999996
Frontiers in microbiology 2022;13:999996
3,3'-diindolylmethane inhibits LPS-induced human chondrocytes apoptosis and extracellular matrix degradation by activating PI3K-Akt-mTOR-mediated autophagy.
Tang H, Qin K, Wang A, Li S, Fang S, Gao W, Lu M, Huang W, Zhang H, Yin Z
Frontiers in pharmacology 2022;13:999851
Frontiers in pharmacology 2022;13:999851
No synergistic effect of fecal microbiota transplantation and shugan decoction in water avoidance stress-induced IBS-D rat model.
Meng Y, Feng Y, Hang L, Zhou Y, Wang E, Yuan J
Frontiers in microbiology 2022;13:995567
Frontiers in microbiology 2022;13:995567
Qing-Re-Xiao-Zheng-Yi-Qi formula relieves kidney damage and activates mitophagy in diabetic kidney disease.
Wu Q, Yan R, Yang H, Wang Y, Zhang C, Zhang J, Cui Z, Wang Y, Sun W
Frontiers in pharmacology 2022;13:992597
Frontiers in pharmacology 2022;13:992597
Bioinformatic analysis of the RNA expression patterns in microgravity-induced bone loss.
Zhang X, Xue T, Hu Z, Guo X, Li G, Wang Y, Zhang L, Xu L, Cao X, Zhang S, Shi F, Wang K
Frontiers in genetics 2022;13:985025
Frontiers in genetics 2022;13:985025
Low FNDC5/Irisin expression is associated with aggressive phenotypes in gastric cancer.
Xu L, Ye Y, Sun Y, Zhong W, Chi L, Lin Y, Liu H, Li S, Chen H, Li C, Lin Y, Wang Q, Xue F, Lin Y
Frontiers in pharmacology 2022;13:981201
Frontiers in pharmacology 2022;13:981201
MiR-146b-5p/TRAF6 axis is essential for Ginkgo biloba L. extract GBE to attenuate LPS-induced neuroinflammation.
Liu M, Peng Y, Che Y, Zhou M, Bai Y, Tang W, Huang S, Zhang B, Deng S, Wang C, Yu Z
Frontiers in pharmacology 2022;13:978587
Frontiers in pharmacology 2022;13:978587
The effects of gut microbiota colonizing on the porcine hypothalamus revealed by whole transcriptome analysis.
Qi R, Wang J, Sun J, Qiu X, Liu X, Wang Q, Yang F, Ge L, Liu Z
Frontiers in microbiology 2022;13:970470
Frontiers in microbiology 2022;13:970470
MiR-93-5p promotes granulosa cell apoptosis and ferroptosis by the NF-kB signaling pathway in polycystic ovary syndrome.
Tan W, Dai F, Yang D, Deng Z, Gu R, Zhao X, Cheng Y
Frontiers in immunology 2022;13:967151
Frontiers in immunology 2022;13:967151
Astragalus saponins and its main constituents ameliorate ductular reaction and liver fibrosis in a mouse model of DDC-induced cholestatic liver disease.
Zhang L, Hu Y, Qi S, Zhang C, Zhou Q, Zhang D, Mu Y, Zhang H, Chen G, Liu P, Chen J, Liu W
Frontiers in pharmacology 2022;13:965914
Frontiers in pharmacology 2022;13:965914
Identification and validation of P4HB as a novel autophagy-related biomarker in diabetic nephropathy.
Bai F, Yu K, Yang Y, Zhang Y, Ding L, An X, Feng F, Sun N, Fan J, Liu L, Yang H, Yang X
Frontiers in genetics 2022;13:965816
Frontiers in genetics 2022;13:965816
Cangfudaotan decoction inhibits mitochondria-dependent apoptosis of granulosa cells in rats with polycystic ovarian syndrome.
Jiang XL, Tai H, Xiao XS, Zhang SY, Cui SC, Qi SB, Hu DD, Zhang LN, Kuang JS, Meng XS, Li SM
Frontiers in endocrinology 2022;13:962154
Frontiers in endocrinology 2022;13:962154
Rabbit hemorrhagic disease virus VP60 protein expressed in recombinant swinepox virus self-assembles into virus-like particles with strong immunogenicity in rabbits.
Liu C, Lin M, Hu H, Liu X, Bian Y, Huang X, Li X, Yu W, Luo F, Deng S
Frontiers in microbiology 2022;13:960374
Frontiers in microbiology 2022;13:960374
Sanguinarine protects against indomethacin-induced small intestine injury in rats by regulating the Nrf2/NF-κB pathways.
Lin XL, Shi YN, Cao YL, Tan X, Zeng YL, Luo ST, Li YM, Qin L, Xia BH, Fu RG, Lin LM, Li K, Cao D, Zeng JG, Liao DF
Frontiers in pharmacology 2022;13:960140
Frontiers in pharmacology 2022;13:960140
MBD2 mediates Th17 cell differentiation by regulating MINK1 in Th17-dominant asthma.
Chen Z, Shang Y, Yuan Y, He Y, Wasti B, Duan W, Ouyang R, Jia J, Xiao B, Zhang D, Zhang X, Li J, Chen B, Liu Y, Zeng Q, Ji X, Ma L, Liu S, Xiang X
Frontiers in genetics 2022;13:959059
Frontiers in genetics 2022;13:959059
Structural and functional analysis of the small GTPase ARF1 reveals a pivotal role of its GTP-binding domain in controlling of the generation of viral inclusion bodies and replication of grass carp reovirus.
Zhang J, Li P, Lu R, Ouyang S, Chang MX
Frontiers in immunology 2022;13:956587
Frontiers in immunology 2022;13:956587
FGFBP1 as a potential biomarker predicting bacillus Calmette-Guérin response in bladder cancer.
Li F, Zhang H, Wang Y, Yao Z, Xie K, Mo Q, Fan Q, Hou L, Deng F, Tan W
Frontiers in immunology 2022;13:954836
Frontiers in immunology 2022;13:954836
Identification of polyunsaturated fatty acids related key modules and genes in metabolic dysfunction-associated fatty liver disease using WGCNA analysis.
Xiao C, Chen S, Yang C, Liu J, Yu M
Frontiers in genetics 2022;13:951224
Frontiers in genetics 2022;13:951224
Therapeutic effects and mechanisms of N-(9,10-anthraquinone-2-ylcarbonyl) xanthine oxidase inhibitors on hyperuricemia.
Gao T, Xu J, Xiao Y, Li J, Hu W, Su X, Shen X, Yu W, Chen Z, Huang B, Li H, Wang X
Frontiers in pharmacology 2022;13:950699
Frontiers in pharmacology 2022;13:950699
Jiangtang Sanhao formula ameliorates skeletal muscle insulin resistance via regulating GLUT4 translocation in diabetic mice.
Ye Z, Ma J, Liu Y, Xu B, Dai X, Fu M, Tian T, Sui X, Mo F, Gao S, Zhao D, Zhang D
Frontiers in pharmacology 2022;13:950535
Frontiers in pharmacology 2022;13:950535
The miR-33a-5p/CROT axis mediates ovarian cancer cell behaviors and chemoresistance via the regulation of the TGF-β signal pathway.
Li X, Gao X, Yuan J, Wang F, Xu X, Wang C, Liu H, Guan W, Zhang J, Xu G
Frontiers in endocrinology 2022;13:950345
Frontiers in endocrinology 2022;13:950345
Esaxerenone inhibits the macrophage-to-myofibroblast transition through mineralocorticoid receptor/TGF-β1 pathway in mice induced with aldosterone.
Qiang P, Hao J, Yang F, Han Y, Chang Y, Xian Y, Xiong Y, Gao X, Liang L, Shimosawa T, Xu Q
Frontiers in immunology 2022;13:948658
Frontiers in immunology 2022;13:948658
Papain-like protease of SARS-CoV-2 inhibits RLR signaling in a deubiquitination-dependent and deubiquitination-independent manner.
Ran XH, Zhu JW, Chen YY, Ni RZ, Mu D
Frontiers in immunology 2022;13:947272
Frontiers in immunology 2022;13:947272
A comprehensively prognostic and immunological analysis of actin-related protein 2/3 complex subunit 5 in pan-cancer and identification in hepatocellular carcinoma.
Huang S, Sun L, Hou P, Liu K, Wu J
Frontiers in immunology 2022;13:944898
Frontiers in immunology 2022;13:944898
Design, synthesis, and biological characterization of a potent STAT3 degrader for the treatment of gastric cancer.
Li H, Wang L, Cao F, Yu D, Yang J, Yu X, Dong J, Qin JJ, Guan X
Frontiers in pharmacology 2022;13:944455
Frontiers in pharmacology 2022;13:944455
EST12 regulates Myc expression and enhances anti-mycobacterial inflammatory response via RACK1-JNK-AP1-Myc immune pathway.
Wu J, Luo FL, Xie Y, Xiong H, Gao Y, Liu G, Zhang XL
Frontiers in immunology 2022;13:943174
Frontiers in immunology 2022;13:943174
A novel CARD11 germline mutation in a Chinese patient of B cell expansion with NF-κB and T cell anergy (BENTA) and literature review.
Zhao P, Hu Y, Sun D, Meng Q, Zhang L, Zhang X, Tan L, Zhang Y, Ding Y, He X
Frontiers in immunology 2022;13:943027
Frontiers in immunology 2022;13:943027
Qu-Du-San-Jie decoction induces growth inhibition and vascular normalization in NF2-associated vestibular schwannoma.
Lin J, Li SW, Zhang J, Chu FH, Li CZ, Bie ZX, Tang HL, Gao S, Li P, Liao MT, Xin TX, Zhao F, Liu PN, Ding X
Frontiers in pharmacology 2022;13:941854
Frontiers in pharmacology 2022;13:941854
Stimulatory G-Protein α Subunit Modulates Endothelial Cell Permeability Through Regulation of Plasmalemma Vesicle-Associated Protein.
He L, Lu H, Ji X, Chu J, Qin X, Chen M, Weinstein LS, Gao J, Yang J, Zhang Q, Zhang C, Zhang W
Frontiers in pharmacology 2022;13:941064
Frontiers in pharmacology 2022;13:941064
Mechanism of Tripterygium wilfordii Hook.F.- Trichosanthes kirilowii Maxim decoction in treatment of diabetic kidney disease based on network pharmacology and molecular docking.
Lu L, Peng J, Wan P, Peng H, Lu J, Xiong G
Frontiers in pharmacology 2022;13:940773
Frontiers in pharmacology 2022;13:940773
Rhein ameliorates transverse aortic constriction-induced cardiac hypertrophy via regulating STAT3 and p38 MAPK signaling pathways.
Li RJ, Xu JJ, Zhang ZH, Chen MW, Liu SX, Yang C, Li YL, Luo P, Liu YJ, Tang R, Shan ZG
Frontiers in pharmacology 2022;13:940574
Frontiers in pharmacology 2022;13:940574
KangPiLao decoction modulates cognitive and emotional disorders in rats with central fatigue through the GABA/Glu pathway.
Xu Y, Lian Y, Li J, Zhang Y, Liu Y, Wang X, Ma J, Li F
Frontiers in pharmacology 2022;13:939169
Frontiers in pharmacology 2022;13:939169
TAZ Induces Migration of Microglia and Promotes Neurological Recovery After Spinal Cord Injury.
Hu X, Huang J, Li Y, Dong L, Chen Y, Ouyang F, Li J, Li Z, Jing J, Cheng L
Frontiers in pharmacology 2022;13:938416
Frontiers in pharmacology 2022;13:938416
Integrated pyroptosis measurement and metabolomics to elucidate the effect and mechanism of tangzhiqing on atherosclerosis.
Chen R, Chen T, Zhou Z, Song Z, Feng W, Yang X, Wang X, Li B, Ding X, Zhang H, Wang Y
Frontiers in physiology 2022;13:937737
Frontiers in physiology 2022;13:937737
Mycoplasma bovis inhibits autophagy in bovine mammary epithelial cells via a PTEN/PI3K-Akt-mTOR-dependent pathway.
Xu M, Liu Y, Mayinuer T, Lin Y, Wang Y, Gao J, Wang D, Kastelic JP, Han B
Frontiers in microbiology 2022;13:935547
Frontiers in microbiology 2022;13:935547
Intestinal Flora-Derived Kynurenic Acid Protects Against Intestinal Damage Caused by Candida albicans Infection via Activation of Aryl Hydrocarbon Receptor.
Wang Z, Yin L, Qi Y, Zhang J, Zhu H, Tang J
Frontiers in microbiology 2022;13:934786
Frontiers in microbiology 2022;13:934786
Effect of Platycodon grandiflorus Polysaccharide on M1 Polarization Induced by Autophagy Degradation of SOCS1/2 Proteins in 3D4/21 Cells.
Li L, Chen X, Lv M, Cheng Z, Liu F, Wang Y, Zhou A, Liu J, Zhao X
Frontiers in immunology 2022;13:934084
Frontiers in immunology 2022;13:934084
Identification of a novel cuproptosis-related gene signature and integrative analyses in patients with lower-grade gliomas.
Bao JH, Lu WC, Duan H, Ye YQ, Li JB, Liao WT, Li YC, Sun YP
Frontiers in immunology 2022;13:933973
Frontiers in immunology 2022;13:933973
Dihydromyricetin ameliorates osteogenic differentiation of human aortic valve interstitial cells by targeting c-KIT/interleukin-6 signaling pathway.
Zhang S, Fan L, Wang Y, Xu J, Shen Q, Xie J, Zeng Z, Zhou T
Frontiers in pharmacology 2022;13:932092
Frontiers in pharmacology 2022;13:932092
Ganfule capsule alleviates bile duct ligation-induced liver fibrosis in mice by inhibiting glutamine metabolism.
Ke C, Gao J, Tu J, Wang Y, Xiao Y, Wu Y, Liu Y, Zhou Z
Frontiers in pharmacology 2022;13:930785
Frontiers in pharmacology 2022;13:930785
Comprehensive analyses identify RIPOR2 as a genomic instability-associated immune prognostic biomarker in cervical cancer.
Xu F, Zou C, Gao Y, Shen J, Liu T, He Q, Li S, Xu S
Frontiers in immunology 2022;13:930488
Frontiers in immunology 2022;13:930488
Blockade of Mbd2 by siRNA-loaded liposomes protects mice against OVA-induced allergic airway inflammation via repressing M2 macrophage production.
Wu GR, Zhou M, Wang Y, Zhou Q, Zhang L, He L, Zhang S, Yu Q, Xu Y, Zhao J, Xiong W, Wang CY
Frontiers in immunology 2022;13:930103
Frontiers in immunology 2022;13:930103
Retinoic Acid Supplementation Rescues the Social Deficits in Fmr1 Knockout Mice.
Yang L, Xia Z, Feng J, Zhang M, Miao P, Nie Y, Zhang X, Hao Z, Hu R
Frontiers in genetics 2022;13:928393
Frontiers in genetics 2022;13:928393
Activation of TRPV4 by lactate as a critical mediator of renal fibrosis in spontaneously hypertensive rats after moderate- and high-intensity exercise.
Zhao B, Xu Y, Chen Y, Cai Y, Gong Z, Li D, Kuang H, Liu X, Zhou H, Liu G, Yin Y
Frontiers in physiology 2022;13:927078
Frontiers in physiology 2022;13:927078
The Proinflammatory Role of Guanylate-Binding Protein 5 in Inflammatory Bowel Diseases.
Li Y, Lin X, Wang W, Wang W, Cheng S, Huang Y, Zou Y, Ke J, Zhu L
Frontiers in microbiology 2022;13:926915
Frontiers in microbiology 2022;13:926915
Transcriptomic Analysis of Dysregulated Genes of the nDNA-mtDNA Axis in a Mouse Model of Dilated Cardiomyopathy.
Ziemann M, Wu W, Deng XL, Du XJ
Frontiers in genetics 2022;13:921610
Frontiers in genetics 2022;13:921610
Icariside Ⅱ Attenuates Palmitic Acid-Induced Endothelial Dysfunction Through SRPK1-Akt-eNOS Signaling Pathway.
Gu YY, Tan XH, Song WP, Song WD, Yuan YM, Xin ZC, Wang JD, Fang D, Guan RL
Frontiers in pharmacology 2022;13:920601
Frontiers in pharmacology 2022;13:920601
Reduced Immunity Regulator MAVS Contributes to Non-Hypertrophic Cardiac Dysfunction by Disturbing Energy Metabolism and Mitochondrial Homeostasis.
Wang Q, Sun Z, Cao S, Lin X, Wu M, Li Y, Yin J, Zhou W, Huang S, Zhang A, Zhang Y, Xia W, Jia Z
Frontiers in immunology 2022;13:919038
Frontiers in immunology 2022;13:919038
Effects and Molecular Regulation Mechanisms of Salinity Stress on the Health and Disease Resistance of Grass Carp.
Fang H, Yang YY, Wu XM, Zheng SY, Song YJ, Zhang J, Chang MX
Frontiers in immunology 2022;13:917497
Frontiers in immunology 2022;13:917497
High expression of ZFP36L2 correlates with the prognosis and immune infiltration in lower-grade glioma.
Zhou M, Li J, Chen C
Frontiers in genetics 2022;13:914219
Frontiers in genetics 2022;13:914219
A Rare Heterozygous TINF2 Deletional Frameshift Mutation in a Chinese Pedigree With a Spectrum of TBDs Phenotypes.
Ren HL, Zheng YC, He GQ, Gao J, Guo X
Frontiers in genetics 2022;13:913133
Frontiers in genetics 2022;13:913133
Brevilin A Ameliorates Acute Lung Injury and Inflammation Through Inhibition of NF-κB Signaling via Targeting IKKα/β.
Liu L, Chen X, Jiang Y, Yuan Y, Yang L, Hu Q, Tang J, Meng X, Xie C, Shen X
Frontiers in pharmacology 2022;13:911157
Frontiers in pharmacology 2022;13:911157
Cyclovirobuxine D Ameliorates Experimental Diabetic Cardiomyopathy by Inhibiting Cardiomyocyte Pyroptosis via NLRP3 in vivo and in vitro.
Gao G, Fu L, Xu Y, Tao L, Guo T, Fang G, Zhang G, Wang S, Qin T, Luo P, Shen X
Frontiers in pharmacology 2022;13:906548
Frontiers in pharmacology 2022;13:906548
Toxoplasma gondii CDPK3 Controls the Intracellular Proliferation of Parasites in Macrophages.
Wu M, An R, Zhou N, Chen Y, Cai H, Yan Q, Wang R, Luo Q, Yu L, Chen L, Du J
Frontiers in immunology 2022;13:905142
Frontiers in immunology 2022;13:905142
Time Series Transcriptomic Analysis by RNA Sequencing Reveals a Key Role of PI3K in Sepsis-Induced Myocardial Injury in Mice.
Yan X, Zhang YL, Han X, Li PB, Guo SB, Li HH
Frontiers in physiology 2022;13:903164
Frontiers in physiology 2022;13:903164
Hepatocyte-Conditional Knockout of Phosphatidylethanolamine Binding Protein 4 Aggravated LPS/D-GalN-Induced Acute Liver Injury via the TLR4/NF-κB Pathway.
Qu XQ, Chen QF, Shi QQ, Luo QQ, Zheng SY, Li YH, Bai LY, Gan S, Zhou XY
Frontiers in immunology 2022;13:901566
Frontiers in immunology 2022;13:901566
Vincristine Promotes Transdifferentiation of Fibroblasts Into Myofibroblasts via P38 and ERK Signal Pathways.
Xu H, Yang J, Tu M, Weng J, Xie M, Zhou Z, Zhou P, Wang L, Chen C, Wang Z
Frontiers in pharmacology 2022;13:901000
Frontiers in pharmacology 2022;13:901000
Csf2ra deletion attenuates acute lung injuries induced by intratracheal inoculation of aerosolized ricin in mice.
Zong F, Li S, Wang Y, Xiao N, Deng M, Zhang Z, Su D, Gao B, Zhou D, Hu L, Yang H
Frontiers in immunology 2022;13:900755
Frontiers in immunology 2022;13:900755
Antisense Oligonucleotide-Based Therapy on miR-181a-5p Alleviates Cartilage Degradation of Temporomandibular Joint Osteoarthritis via Promoting SIRT1.
Qi H, Zhao Z, Xu L, Zhang Y, Li Y, Xiao L, Li Y, Zhao Z, Fang J
Frontiers in pharmacology 2022;13:898334
Frontiers in pharmacology 2022;13:898334
Hydrogen Repairs LPS-Induced Endothelial Progenitor Cells Injury via PI3K/AKT/eNOS Pathway.
Mu Q, Lv K, Yu J, Chu S, Zhang L, Kong L, Zhang L, Tian Y, Jia X, Liu B, Wei Y, Yang N
Frontiers in pharmacology 2022;13:894812
Frontiers in pharmacology 2022;13:894812
CNST is Characteristic of Leukemia Stem Cells and is Associated With Poor Prognosis in AML.
Liu H, Zhang X, Zhao Z, Zhu H, Li D, Yang Y, Zhao W, Zhang F, Wang Y, Zhu L, Ding Z, Li X
Frontiers in pharmacology 2022;13:888243
Frontiers in pharmacology 2022;13:888243
Epigenetic Reader Bromodomain Containing Protein 2 Facilitates Pathological Cardiac Hypertrophy via Regulating the Expression of Citrate Cycle Genes.
Lin Z, Li Z, Guo Z, Cao Y, Li J, Liu P, Li Z
Frontiers in pharmacology 2022;13:887991
Frontiers in pharmacology 2022;13:887991
Metformin Ameliorates Chronic Colitis-Related Intestinal Fibrosis via Inhibiting TGF-β1/Smad3 Signaling.
Wang Y, Wang Z, Yang H, Chen S, Zheng D, Liu X, Jiang Q, Chen Y
Frontiers in pharmacology 2022;13:887497
Frontiers in pharmacology 2022;13:887497
Solamargine Inhibits the Development of Hypopharyngeal Squamous Cell Carcinoma by Decreasing LncRNA HOXA11-As Expression.
Meng Y, Jin M, Yuan D, Zhao Y, Kong X, Guo X, Wang X, Hou J, Wang B, Song W, Tang Y
Frontiers in pharmacology 2022;13:887387
Frontiers in pharmacology 2022;13:887387
The Dibenzyl Isoquinoline Alkaloid Berbamine Ameliorates Osteoporosis by Inhibiting Bone Resorption.
Zhang C, Zhong Z, Sang W, Ghorbani F, Ghalandari B, Mohamadali M, Irani S, Qian Z, Yi C, Yu B
Frontiers in endocrinology 2022;13:885507
Frontiers in endocrinology 2022;13:885507
Immune Dysfunction Mediated by the ceRNA Regulatory Network in Human Placenta Tissue of Intrahepatic Cholestasis Pregnancy.
Wang Y, Tang Y, Yang X, Xu J, Chen Y, Xu J, Hu S, Yi P
Frontiers in immunology 2022;13:883971
Frontiers in immunology 2022;13:883971
Transcriptome Analysis Reveals Key miRNA-mRNA Pathways in Ovarian Tissues of Yunshang Black Goats With Different Kidding Numbers.
Liu Y, Zhou Z, Guo S, Li K, Wang P, Fan Y, He X, Jiang Y, Lan R, Chen S, Dai S, Hong Q, Chu M
Frontiers in endocrinology 2022;13:883663
Frontiers in endocrinology 2022;13:883663
Hepatoprotective Effects of Glycyrrhetinic Acid on Lithocholic Acid-Induced Cholestatic Liver Injury Through Choleretic and Anti-Inflammatory Mechanisms.
Wang Q, Song GC, Weng FY, Zou B, Jin JY, Yan DM, Tan B, Zhao J, Li Y, Qiu FR
Frontiers in pharmacology 2022;13:881231
Frontiers in pharmacology 2022;13:881231
Obeticholic Acid Induces Hepatoxicity Via FXR in the NAFLD Mice.
Lin C, Yu B, Chen L, Zhang Z, Ye W, Zhong H, Bai W, Yang Y, Nie B
Frontiers in pharmacology 2022;13:880508
Frontiers in pharmacology 2022;13:880508
Natural Compound ZINC12899676 Reduces Porcine Epidemic Diarrhea Virus Replication by Inhibiting the Viral NTPase Activity.
Wang P, Wang X, Liu X, Sun M, Liang X, Bai J, Jiang P
Frontiers in pharmacology 2022;13:879733
Frontiers in pharmacology 2022;13:879733
Myeloid Angiotensin II Type 1 Receptor Mediates Macrophage Polarization and Promotes Vascular Injury in DOCA/Salt Hypertensive Mice.
Yang XF, Wang H, Huang Y, Huang JH, Ren HL, Xu Q, Su XM, Wang AM, Ren F, Zhou MS
Frontiers in pharmacology 2022;13:879693
Frontiers in pharmacology 2022;13:879693
Targeting Mitochondrial ROS-Mediated Ferroptosis by Quercetin Alleviates High-Fat Diet-Induced Hepatic Lipotoxicity.
Jiang JJ, Zhang GF, Zheng JY, Sun JH, Ding SB
Frontiers in pharmacology 2022;13:876550
Frontiers in pharmacology 2022;13:876550
The Bradykinin System Contributes to the Regulation of Prostaglandin-Endoperoxide Synthase 2 Expression in Human Amnion Fibroblasts: Implications for Term and Preterm Birth.
Ni XT, Wang WS, Liu Y, Lin YK, Zhang F, Lei WJ, Ling LJ, Pan F, Zhu YN, Li MD, Duan T, Liu M, Sun K
Frontiers in endocrinology 2022;13:873727
Frontiers in endocrinology 2022;13:873727
Astragaloside IV Alleviates Intestinal Barrier Dysfunction via the AKT-GSK3β-β-Catenin Pathway in Peritoneal Dialysis.
He J, Wang M, Yang L, Xin H, Bian F, Jiang G, Zhang X
Frontiers in pharmacology 2022;13:873150
Frontiers in pharmacology 2022;13:873150
Neutrophil Extracellular Traps (NETs) Promote Non-Small Cell Lung Cancer Metastasis by Suppressing lncRNA MIR503HG to Activate the NF-κB/NLRP3 Inflammasome Pathway.
Wang Y, Liu F, Chen L, Fang C, Li S, Yuan S, Qian X, Yin Y, Yu B, Fu B, Zhang X, Li Y
Frontiers in immunology 2022;13:867516
Frontiers in immunology 2022;13:867516
A Novel STAT3 Gain-of-Function Mutation in Fatal Infancy-Onset Interstitial Lung Disease.
Deng M, Li Y, Li Y, Mao X, Ke H, Liang W, Lei X, Lau YL, Mao H
Frontiers in immunology 2022;13:866638
Frontiers in immunology 2022;13:866638
Maresin1 Protect Against Ferroptosis-Induced Liver Injury Through ROS Inhibition and Nrf2/HO-1/GPX4 Activation.
Yang W, Wang Y, Zhang C, Huang Y, Yu J, Shi L, Zhang P, Yin Y, Li R, Tao K
Frontiers in pharmacology 2022;13:865689
Frontiers in pharmacology 2022;13:865689
Scorias spongiosa Polysaccharides Promote the Antioxidant and Anti-Inflammatory Capacity and Its Effect on Intestinal Microbiota in Mice.
Xu Y, Zhang Z, Feng H, Tang J, Peng W, Chen Y, Zhou J, Wang Y
Frontiers in microbiology 2022;13:865396
Frontiers in microbiology 2022;13:865396
Glucocorticoid induced group 2 innate lymphoid cell overactivation exacerbates experimental colitis.
Feng B, Lin L, Li L, Long X, Liu C, Zhao Z, Li S, Li Y
Frontiers in immunology 2022;13:863034
Frontiers in immunology 2022;13:863034
Polydatin Glycosides Improve Monocrotaline-Induced Pulmonary Hypertension Injury by Inhibiting Endothelial-To-Mesenchymal Transition.
Chen X, He Y, Yu Z, Zuo J, Huang Y, Ruan Y, Zheng X, Ma Y
Frontiers in pharmacology 2022;13:862017
Frontiers in pharmacology 2022;13:862017
Theaflavin-3,3'-Digallate from Black Tea Inhibits Neointima Formation Through Suppression of the PDGFRβ Pathway in Vascular Smooth Muscle Cells.
Wu Y, Chen M, Chen Z, Shu J, Zhang L, Hu J, Yu H, Huang K, Liang M
Frontiers in pharmacology 2022;13:861319
Frontiers in pharmacology 2022;13:861319
Rosmarinic Acid Ameliorates Pulmonary Ischemia/Reperfusion Injury by Activating the PI3K/Akt Signaling Pathway.
Luo W, Tao Y, Chen S, Luo H, Li X, Qu S, Chen K, Zeng C
Frontiers in pharmacology 2022;13:860944
Frontiers in pharmacology 2022;13:860944
S100P promotes trophoblast syncytialization during early placenta development by regulating YAP1.
Zhou H, Pan Y, Yang W, Zhao C, Sun X, Hong B, Jin X, Zhang T, Zhang Y, Liu N, Zhang S, Zhu H
Frontiers in endocrinology 2022;13:860261
Frontiers in endocrinology 2022;13:860261
Analysis of Interaction Network Between Host Protein and M Protein of Swine Acute Diarrhea Syndrome Coronavirus.
Xu J, Cao Z, Ji C, Zhou L, Yan X, Sun Y, Ma J
Frontiers in microbiology 2022;13:858460
Frontiers in microbiology 2022;13:858460
YTHDF1 Negatively Regulates Treponema pallidum-Induced Inflammation in THP-1 Macrophages by Promoting SOCS3 Translation in an m6A-Dependent Manner.
Li Z, Teng M, Jiang Y, Zhang L, Luo X, Liao Y, Yang B
Frontiers in immunology 2022;13:857727
Frontiers in immunology 2022;13:857727
Single Cell Dissection of Epithelial-Immune Cellular Interplay in Acute Kidney Injury Microenvironment.
Zhang M, Wu L, Deng Y, Peng F, Wang T, Zhao Y, Chen P, Liu J, Cai G, Wang L, Wu J, Chen X
Frontiers in immunology 2022;13:857025
Frontiers in immunology 2022;13:857025
Construction of a Novel LncRNA Signature Related to Genomic Instability to Predict the Prognosis and Immune Activity of Patients With Hepatocellular Carcinoma.
Zhu J, Huang Q, Liu S, Peng X, Xue J, Feng T, Huang W, Chen Z, Lai K, Ji Y, Wang M, Yuan R
Frontiers in immunology 2022;13:856186
Frontiers in immunology 2022;13:856186
Continuous Activation of Dopamine Receptors Alleviates LPS-Induced Liver Injury in Mice via β-arrestin2 Dependent Akt/NF-κB Pathway.
Li M, Zhang C, Zhou L, Sun X, Wang T, Fu F
Frontiers in pharmacology 2022;13:853834
Frontiers in pharmacology 2022;13:853834
LncRNA NEAT1 Potentiates SREBP2 Activity to Promote Inflammatory Macrophage Activation and Limit Hantaan Virus Propagation.
Yang Y, Li M, Ma Y, Ye W, Si Y, Zheng X, Liu H, Cheng L, Zhang L, Zhang H, Zhang X, Lei Y, Shen L, Zhang F, Ma H
Frontiers in microbiology 2022;13:849020
Frontiers in microbiology 2022;13:849020
KIFC3 Promotes Proliferation, Migration, and Invasion in Colorectal Cancer via PI3K/AKT/mTOR Signaling Pathway.
Liao H, Zhang L, Lu S, Li W, Dong W
Frontiers in genetics 2022;13:848926
Frontiers in genetics 2022;13:848926
Super-Enhancer-Associated Long Non-Coding RNA LINC01485 Promotes Osteogenic Differentiation of Human Bone Marrow Mesenchymal Stem Cells by Regulating MiR-619-5p/RUNX2 Axis.
Gu W, Jiang X, Wang W, Mujagond P, Liu J, Mai Z, Tang H, Li S, Xiao H, Zhao J
Frontiers in endocrinology 2022;13:846154
Frontiers in endocrinology 2022;13:846154
ASF1B is a Promising Prognostic Biomarker and Correlates With Immunotherapy Efficacy in Hepatocellular Carcinoma.
Zhang S, Xu L, Feng J, Tan D, Zhu Y, Hou J, Li W, Lv K, Wang W, Jiang L, Jiao M, Guo H
Frontiers in genetics 2022;13:842351
Frontiers in genetics 2022;13:842351
Restoring Impaired Fertility Through Diet: Observations of Switching From High-Fat Diet During Puberty to Normal Diet in Adulthood Among Obese Male Mice.
Qi X, Zhang M, Sun M, Luo D, Guan Q, Yu C
Frontiers in endocrinology 2022;13:839034
Frontiers in endocrinology 2022;13:839034
IL25 Enhanced Colitis-Associated Tumorigenesis in Mice by Upregulating Transcription Factor GLI1.
Liu J, Qian B, Zhou L, Shen G, Tan Y, Liu S, Zhao Z, Shi J, Qi W, Zhou T, Yang X, Gao G, Yang Z
Frontiers in immunology 2022;13:837262
Frontiers in immunology 2022;13:837262
Multiple SARS-CoV-2 Variants Exhibit Variable Target Cell Infectivity and Ability to Evade Antibody Neutralization.
Tang H, Gao L, Wu Z, Meng F, Zhao X, Shao Y, Hou G, Du X, Qin FX
Frontiers in immunology 2022;13:836232
Frontiers in immunology 2022;13:836232
Matrix Remodeling-Associated Protein 8 as a Novel Indicator Contributing to Glioma Immune Response by Regulating Ferroptosis.
Xu Z, Chen X, Song L, Yuan F, Yan Y
Frontiers in immunology 2022;13:834595
Frontiers in immunology 2022;13:834595
The Effect of Blood Flow-Restricted Low Resistance Training on Microvascular Circulation of Myocardium in Spontaneously Hypertensive Rats.
Tan Z, Zhao Y, Zheng Y, Pan Y
Frontiers in physiology 2022;13:829718
Frontiers in physiology 2022;13:829718
The Role of RAB GTPases and Its Potential in Predicting Immunotherapy Response and Prognosis in Colorectal Cancer.
Jiang X, Yang L, Gao Q, Liu Y, Feng X, Ye S, Yang Z
Frontiers in genetics 2022;13:828373
Frontiers in genetics 2022;13:828373
Identification of a De Novo Heterozygous Missense ACTB Variant in Baraitser-Winter Cerebrofrontofacial Syndrome.
Nie K, Huang J, Liu L, Lv H, Chen D, Fan W
Frontiers in genetics 2022;13:828120
Frontiers in genetics 2022;13:828120
Sirtuin 2 Alleviates Chronic Neuropathic Pain by Suppressing Ferroptosis in Rats.
Zhang X, Song T, Zhao M, Tao X, Zhang B, Sun C, Wang P, Wang K, Zhao L
Frontiers in pharmacology 2022;13:827016
Frontiers in pharmacology 2022;13:827016
Induction of Collagen I by CXCL10 in Ovarian Theca-Stroma Cells via the JNK Pathway.
Wang C, Sun Y
Frontiers in endocrinology 2022;13:823740
Frontiers in endocrinology 2022;13:823740
NUSAP1 Could be a Potential Target for Preventing NAFLD Progression to Liver Cancer.
Zeng T, Chen G, Qiao X, Chen H, Sun L, Ma Q, Li N, Wang J, Dai C, Xu F
Frontiers in pharmacology 2022;13:823140
Frontiers in pharmacology 2022;13:823140
Estradiol Ameliorates Acute Kidney Ischemia-Reperfusion Injury by Inhibiting the TGF-βRI-SMAD Pathway.
Ren L, Li F, Di Z, Xiong Y, Zhang S, Ma Q, Bian X, Lang Z, Ye Q, Wang Y
Frontiers in immunology 2022;13:822604
Frontiers in immunology 2022;13:822604
Simvastatin Downregulates the SARS-CoV-2-Induced Inflammatory Response and Impairs Viral Infection Through Disruption of Lipid Rafts.
Teixeira L, Temerozo JR, Pereira-Dutra FS, Ferreira AC, Mattos M, Gonçalves BS, Sacramento CQ, Palhinha L, Cunha-Fernandes T, Dias SSG, Soares VC, Barreto EA, Cesar-Silva D, Fintelman-Rodrigues N, Pão CRR, de Freitas CS, Reis PA, Hottz ED, Bozza FA, Bou-Habib DC, Saraiva EM, de Almeida CJG, Viola JPB, Souza TML, Bozza PT
Frontiers in immunology 2022;13:820131
Frontiers in immunology 2022;13:820131
Punicalagin Alleviates Psoriasis by Inhibiting NF-κB-Mediated IL-1β Transcription and Caspase-1-Regulated IL-1β Secretion.
Tang L, Li T, Zhang B, Zhang Z, Sun X, Zhu Y, Feng B, Su Z, Yang L, Li H, Liu H, Chen Y, Dai Z, Zheng X, Li M, Li C, Zhao J, Qiu X, Ye S, Liu H, Zheng G, Li B, Lu C
Frontiers in pharmacology 2022;13:817526
Frontiers in pharmacology 2022;13:817526
Miya Improves Osteoarthritis Characteristics via the Gut-Muscle-Joint Axis According to Multi-Omics Analyses.
Xu T, Yang D, Liu K, Gao Q, Liu Z, Li G
Frontiers in pharmacology 2022;13:816891
Frontiers in pharmacology 2022;13:816891
Celastrol Alleviates Autoimmune Hepatitis Through the PI3K/AKT Signaling Pathway Based on Network Pharmacology and Experiments.
Wang S, Huang Z, Lei Y, Han X, Tian D, Gong J, Liu M
Frontiers in pharmacology 2022;13:816350
Frontiers in pharmacology 2022;13:816350
Berberine Improves Vascular Dysfunction by Inhibiting Trimethylamine-N-oxide via Regulating the Gut Microbiota in Angiotensin II-Induced Hypertensive Mice.
Wang Z, Wu F, Zhou Q, Qiu Y, Zhang J, Tu Q, Zhou Z, Shao Y, Xu S, Wang Y, Tao J
Frontiers in microbiology 2022;13:814855
Frontiers in microbiology 2022;13:814855
Sodium Butyrate Attenuates Taurocholate-Induced Acute Pancreatitis by Maintaining Colonic Barrier and Regulating Gut Microorganisms in Mice.
Xiong Y, Ji L, Zhao Y, Liu A, Wu D, Qian J
Frontiers in physiology 2022;13:813735
Frontiers in physiology 2022;13:813735
Scalable Dual-Fluorescence Assay for Functional Interpretation of HNF-4α Missense Variants.
Guo Y, Zhao J, Huang R, Xu T, Zhou K, Zheng L
Frontiers in endocrinology 2022;13:812747
Frontiers in endocrinology 2022;13:812747
Interleukin-25-Mediated-IL-17RB Upregulation Promotes Cutaneous Wound Healing in Diabetic Mice by Improving Endothelial Cell Functions.
Zhang F, Liu Y, Wang S, Yan X, Lin Y, Chen D, Tan Q, Wu Z
Frontiers in immunology 2022;13:809755
Frontiers in immunology 2022;13:809755
Naoluo Xintong Decoction in the Treatment of Ischemic Stroke: A Network Analysis of the Mechanism of Action.
Wang N, Chu F, Fei C, Pan L, Wang Y, Chen W, Peng D, Duan X, He L
Frontiers in pharmacology 2022;13:809505
Frontiers in pharmacology 2022;13:809505
An Herbal Product Alleviates Bleomycin-Induced Pulmonary Fibrosis in Mice via Regulating NF-κB/TNF-α Signaling in Macrophages.
Jing F, Chen X, Xue J, Huang K, Xing F, Hu X, Peng Y, Liu C
Frontiers in pharmacology 2022;13:805432
Frontiers in pharmacology 2022;13:805432
Tormentic Acid Ameliorates Hepatic Fibrosis in vivo by Inhibiting Glycerophospholipids Metabolism and PI3K/Akt/mTOR and NF-κB Pathways: Based on Transcriptomics and Metabolomics.
Lin X, Wei Y, Li Y, Xiong Y, Fang B, Li C, Huang Q, Huang R, Wei J
Frontiers in pharmacology 2022;13:801982
Frontiers in pharmacology 2022;13:801982
Deferoxamine Alleviates Osteoarthritis by Inhibiting Chondrocyte Ferroptosis and Activating the Nrf2 Pathway.
Guo Z, Lin J, Sun K, Guo J, Yao X, Wang G, Hou L, Xu J, Guo J, Guo F
Frontiers in pharmacology 2022;13:791376
Frontiers in pharmacology 2022;13:791376
Androgen Excess Induced Mitochondrial Abnormality in Ovarian Granulosa Cells in a Rat Model of Polycystic Ovary Syndrome.
Song L, Yu J, Zhang D, Li X, Chen L, Cai Z, Yu C
Frontiers in endocrinology 2022;13:789008
Frontiers in endocrinology 2022;13:789008
Comprehensive Analysis of LncRNA AC010789.1 Delays Androgenic Alopecia Progression by Targeting MicroRNA-21 and the Wnt/β-Catenin Signaling Pathway in Hair Follicle Stem Cells.
Xiong J, Wu B, Hou Q, Huang X, Jia L, Li Y, Jiang H
Frontiers in genetics 2022;13:782750
Frontiers in genetics 2022;13:782750
Thymopentin-Mediated Inhibition of Cancer Stem Cell Stemness Enhances the Cytotoxic Effect of Oxaliplatin on Colon Cancer Cells.
Yu PC, Liu D, Han ZX, Liang F, Hao CY, Lei YT, Guo CR, Wang WH, Li XH, Yang XN, Li CZ, Yu Y, Fan YZ
Frontiers in pharmacology 2022;13:779715
Frontiers in pharmacology 2022;13:779715
Delivery of Basic Fibroblast Growth Factor Through an In Situ Forming Smart Hydrogel Activates Autophagy in Schwann Cells and Improves Facial Nerves Generation via the PAK-1 Signaling Pathway.
Hu B, Zhang H, Xu M, Li L, Wu M, Zhang S, Liu X, Xia W, Xu K, Xiao J, Zhang H, Ni L
Frontiers in pharmacology 2022;13:778680
Frontiers in pharmacology 2022;13:778680
Aberrant Expression of ADARB1 Facilitates Temozolomide Chemoresistance and Immune Infiltration in Glioblastoma.
Lu C, Chen X, Yan Y, Ren X, Wang X, Peng B, Cai Y, Liang Q, Xu Z, Peng J
Frontiers in pharmacology 2022;13:768743
Frontiers in pharmacology 2022;13:768743
Deficiency of RARα Suppresses Decidualization via Downregulating CEBPB Transcription in Women With Recurrent Implantation Failure.
Huang C, Zhang Q, Ni T, Zhou T, Lv C, Li Y, Yan J, Chen ZJ
Frontiers in endocrinology 2022;13:753416
Frontiers in endocrinology 2022;13:753416
TREM2 is associated with tumor immunity and implies poor prognosis in glioma.
Yu M, Chang Y, Zhai Y, Pang B, Wang P, Li G, Jiang T, Zeng F
Frontiers in immunology 2022;13:1089266
Frontiers in immunology 2022;13:1089266
Creatine modulates cellular energy metabolism and protects against cancer cachexia-associated muscle wasting.
Wei L, Wang R, Lin K, Jin X, Li L, Wazir J, Pu W, Lian P, Lu R, Song S, Zhao Q, Li J, Wang H
Frontiers in pharmacology 2022;13:1086662
Frontiers in pharmacology 2022;13:1086662
Long non-coding RNA SNHG9 regulates viral replication in rhabdomyosarcoma cells infected with enterovirus D68 via miR-150-5p/c-Fos axis.
Fu H, Si J, Xu L, Tang X, He Y, Lu N, Li H, Li A, Gao S, Yang C
Frontiers in microbiology 2022;13:1081237
Frontiers in microbiology 2022;13:1081237
Arbitrary Ca(2+) regulation for endothelial nitric oxide, NFAT and NF-κB activities by an optogenetic approach.
Yamanaka T, Ueki T, Mase M, Inoue K
Frontiers in pharmacology 2022;13:1076116
Frontiers in pharmacology 2022;13:1076116
Overnutrition-induced gout: An immune response to NLRP3 inflammasome dysregulation by XOD activity increased in quail.
Wu H, Wang Y, Ren Z, Li Y, Huang J, Lin Z, Zhang B
Frontiers in immunology 2022;13:1074867
Frontiers in immunology 2022;13:1074867
Oroxin B alleviates osteoarthritis through anti-inflammation and inhibition of PI3K/AKT/mTOR signaling pathway and enhancement of autophagy.
Lu R, He Z, Zhang W, Wang Y, Cheng P, Lv Z, Yuan X, Guo F, You H, Chen AM, Hu W
Frontiers in endocrinology 2022;13:1060721
Frontiers in endocrinology 2022;13:1060721
Novel insight of N(6)-methyladenosine modified subtypes in abdominal aortic aneurysm.
Wang K, Kan Q, Ye Y, Qiu J, Huang L, Wu R, Yao C
Frontiers in genetics 2022;13:1055396
Frontiers in genetics 2022;13:1055396
AIM2 inflammasome activation benefits the therapeutic effect of BCG in bladder carcinoma.
Zhou H, Zhang L, Luo W, Hong H, Tang D, Zhou D, Zhou L, Li Y
Frontiers in pharmacology 2022;13:1050774
Frontiers in pharmacology 2022;13:1050774
Protective effects of mefunidone on ischemia-reperfusion injury/Folic acid-induced acute kidney injury.
Li J, Jiang Y, Dai Q, Yu Y, Lv X, Zhang Y, Liao X, Ao L, Hu G, Meng J, Peng Z, Tao L, Xie Y
Frontiers in pharmacology 2022;13:1043945
Frontiers in pharmacology 2022;13:1043945
Regulation of Yujin Powder alcoholic extracts on ILC3s-TD IgA-colonic mucosal flora axis of DSS-induced ulcerative colitis.
Wen Y, Zhang W, Yang R, Jiang L, Zhang X, Wang B, Hua Y, Ji P, Yuan Z, Wei Y, Yao W
Frontiers in microbiology 2022;13:1039884
Frontiers in microbiology 2022;13:1039884
Malvidin alleviates mitochondrial dysfunction and ROS accumulation through activating AMPK-α/UCP2 axis, thereby resisting inflammation and apoptosis in SAE mice.
Zhao P, Li X, Yang Q, Lu Y, Wang G, Yang H, Dong J, Zhang H
Frontiers in pharmacology 2022;13:1038802
Frontiers in pharmacology 2022;13:1038802
Potential cardiotoxicity induced by Euodiae Fructus: In vivo and in vitro experiments and untargeted metabolomics research.
Zhang D, Lü J, Ren Z, Zhang X, Wu H, Sa R, Wang X, Wang Y, Lin Z, Zhang B
Frontiers in pharmacology 2022;13:1028046
Frontiers in pharmacology 2022;13:1028046
Ginkgolide C slows the progression of osteoarthritis by activating Nrf2/HO-1 and blocking the NF-κB pathway.
Ma T, Jia L, Zhao J, Lv L, Yu Y, Ruan H, Song X, Chen H, Li X, Zhang J, Gao L
Frontiers in pharmacology 2022;13:1027553
Frontiers in pharmacology 2022;13:1027553
Crosstalk of necroptosis and pyroptosis defines tumor microenvironment characterization and predicts prognosis in clear cell renal carcinoma.
Fu L, Bao J, Li J, Li Q, Lin H, Zhou Y, Li J, Yan Y, Langston ME, Sun T, Guo S, Zhou X, Chen Y, Liu Y, Zhao Y, Lu J, Huang Y, Chen W, Chung BI, Luo J
Frontiers in immunology 2022;13:1021935
Frontiers in immunology 2022;13:1021935
Lipidomics reveals the potential mechanism of honokiol against adenine-induced chronic kidney disease.
Liu X, Gao L, Huang X, Deng R, Wei X, Lu J, Li S
Frontiers in pharmacology 2022;13:1019629
Frontiers in pharmacology 2022;13:1019629
Quantification of promoting efficiency and reducing toxicity of Traditional Chinese Medicine: A case study of the combination of Tripterygium wilfordii hook. f. and Lysimachia christinae hance in the treatment of lung cancer.
Zhang X, Wang K, Dai H, Cai J, Liu Y, Yin C, Wu J, Li X, Wu G, Lu A, Liu Q, Guan D
Frontiers in pharmacology 2022;13:1018273
Frontiers in pharmacology 2022;13:1018273
Immunostimulatory activity and structure-activity relationship of epimedin B from Epimedium brevicornu Maxim.
Gao Y, Shi W, Tu C, Li P, Zhao G, Xiao X, Wang J, Bai Z
Frontiers in pharmacology 2022;13:1015846
Frontiers in pharmacology 2022;13:1015846
X-box binding protein 1: A new metabolic mediator and drug target of metformin?
Lou K, Sun P, Zhang C, Jiang Q, Pang S
Frontiers in pharmacology 2022;13:1013218
Frontiers in pharmacology 2022;13:1013218
Melatonin inhibits HCC progression through regulating the alternative splicing of NEMO.
Bai L, Sun S, Su W, Chen C, Lv Y, Zhang J, Zhao J, Li M, Qi Y, Zhang W, Wang Y
Frontiers in pharmacology 2022;13:1007006
Frontiers in pharmacology 2022;13:1007006
African swine fever virus infection activates inflammatory responses through downregulation of the anti-inflammatory molecule C1QTNF3.
Lv C, Zhang Q, Zhao L, Yang J, Zou Z, Zhao Y, Li C, Sun X, Lin X, Jin M
Frontiers in immunology 2022;13:1002616
Frontiers in immunology 2022;13:1002616
METTL3/m(6)A/IFIT2 regulates proliferation, invasion and immunity in esophageal squamous cell carcinoma.
Ge F, Li Z, Hu J, Pu Y, Zhao F, Kong L
Frontiers in pharmacology 2022;13:1002565
Frontiers in pharmacology 2022;13:1002565
Prrx1 promotes resistance to temozolomide by upregulating ABCC1 and inducing vasculogenic mimicry in glioma.
Chen Z, Zhang Y, Chen Y, Lin W, Zhang Y, Cai G, Sun X, Zheng K, He J, Ai T, Wang J, Zhao L, Ke Y
American journal of cancer research 2022;12(8):3892-3912
American journal of cancer research 2022;12(8):3892-3912
MYBL2 accelerates epithelial-mesenchymal transition and hepatoblastoma metastasis via the Smad/SNAI1 pathway.
Wei M, Yang R, Ye M, Zhan Y, Liu B, Meng L, Xie L, Du M, Wang J, Gao R, Chen D, Dong R, Dong K
American journal of cancer research 2022;12(5):1960-1981
American journal of cancer research 2022;12(5):1960-1981
Decreased RNA m(6)A methylation enhances the process of the epithelial mesenchymal transition and vasculogenic mimicry in glioblastoma.
Tao M, Li X, He L, Rong X, Wang H, Pan J, Lu Z, Zhang X, Peng Y
American journal of cancer research 2022;12(2):893-906
American journal of cancer research 2022;12(2):893-906
5-aza-2'-deoxycytidine potentiates anti-tumor immunity in colorectal peritoneal metastasis by modulating ABC A9-mediated cholesterol accumulation in macrophages.
Shi R, Zhao K, Wang T, Yuan J, Zhang D, Xiang W, Qian J, Luo N, Zhou Y, Tang B, Li C, Miao H
Theranostics 2022;12(2):875-890
Theranostics 2022;12(2):875-890
Nintedanib enhances the efficacy of PD-L1 blockade by upregulating MHC-I and PD-L1 expression in tumor cells.
Tu J, Xu H, Ma L, Li C, Qin W, Chen X, Yi M, Sun L, Liu B, Yuan X
Theranostics 2022;12(2):747-766
Theranostics 2022;12(2):747-766
circHIPK3 prevents cardiac senescence by acting as a scaffold to recruit ubiquitin ligase to degrade HuR.
Ding F, Lu L, Wu C, Pan X, Liu B, Zhang Y, Wang Y, Wu W, Yan B, Zhang Y, Yu XY, Li Y
Theranostics 2022;12(17):7550-7566
Theranostics 2022;12(17):7550-7566
The PROTAC selectively degrading Bcl-x(L) represents a novel Hedgehog pathway inhibitor with capacity of combating resistance to Smoothened inhibitors while sparing bone growth.
Zhang S, Chen Y, Xu Z, Yang J, Sun R, Wang J, Sun Y, Jiang B, Yang X, Tan W
Theranostics 2022;12(17):7476-7490
Theranostics 2022;12(17):7476-7490
Hippocalcin-Like 1 blunts liver lipid metabolism to suppress tumorigenesis via directly targeting RUVBL1-mTOR signaling.
Chen T, Yuan Z, Lei Z, Duan J, Xue J, Lu T, Yan G, Zhang L, Liu Y, Li Q, Zhang Y
Theranostics 2022;12(17):7450-7464
Theranostics 2022;12(17):7450-7464
Ninj2 regulates Schwann cells development by interfering laminin-integrin signaling.
Sun Y, Chen X, Yue C, Yang W, Zhang S, Ou Z, Chen Y
Theranostics 2022;12(17):7307-7318
Theranostics 2022;12(17):7307-7318
Yap1 modulates cardiomyocyte hypertrophy via impaired mitochondrial biogenesis in response to chronic mechanical stress overload.
Yue P, Zhang Y, Liu L, Zhou K, Xia S, Peng M, Yan H, Tang X, Chen Z, Zhang D, Guo J, Pu WT, Guo Y, Hua Y, Li Y
Theranostics 2022;12(16):7009-7031
Theranostics 2022;12(16):7009-7031
UBR5 promotes tumor immune evasion through enhancing IFN-γ-induced PDL1 transcription in triple negative breast cancer.
Wu B, Song M, Dong Q, Xiang G, Li J, Ma X, Wei F
Theranostics 2022;12(11):5086-5102
Theranostics 2022;12(11):5086-5102
Multi-omics analysis of kinesin family member 2C in human tumors: novel prognostic biomarker and tumor microenvironment regulator.
Zhang B, Liu P, Li Y, Hu Q, Li H, Pang X, Wu H
American journal of cancer research 2022;12(11):4954-4976
American journal of cancer research 2022;12(11):4954-4976
Deglycosylation of SLAMF7 in breast cancers enhances phagocytosis.
Wang SH, Chou WC, Huang HC, Lee TA, Hsiao TC, Wang LH, Huang KB, Kuo CT, Chao CH, Chang SJ, Hsu JM, Weng J, Ren N, Li FA, Lai YJ, Zhou C, Hung MC, Li CW
American journal of cancer research 2022;12(10):4721-4736
American journal of cancer research 2022;12(10):4721-4736
Blockade of phosphotyrosine pathways suggesting SH2 superbinder as a novel therapy for pulmonary fibrosis.
Wang M, Liu AD, Niu Q, Feng X, Zheng YY, Chen SJ, Xu H, Li Q, Hou GQ, Bi XY, Lu YZ, Cheng PP, Liang LM, Jiang YH, Zhao LQ, Liu F, Song LJ, Zhou LL, Xiao LY, Chen F, Li SS, Ma WL, Cao X, Ye H
Theranostics 2022;12(10):4513-4535
Theranostics 2022;12(10):4513-4535
Consequences of somatic mutations of GIRK1 detected in primary malign tumors on expression and function of G-protein activated, inwardly rectifying, K(+) channels.
Pelzmann B, Hatab A, Scheruebel S, Langthaler S, Rienmueller T, Sokolowski A, Gorischek A, Platzer D, Zorn-Pauly K, Jahn SW, Bauernhofer T, Schreibmayer W
Frontiers in oncology 2022;12:998907
Frontiers in oncology 2022;12:998907
Parthenolide and arsenic trioxide co-trigger autophagy-accompanied apoptosis in hepatocellular carcinoma cells.
Yi J, Gong X, Yin XY, Wang L, Hou JX, Chen J, Xie B, Chen G, Wang LN, Wang XY, Wang DC, Wei HL
Frontiers in oncology 2022;12:988528
Frontiers in oncology 2022;12:988528
INPP4B inhibits glioma cell proliferation and immune escape via inhibition of the PI3K/AKT signaling pathway.
Sun X, Chen Y, Tao X, Zhang W, Wang X, Wang X, Ruan Z, Chen Z
Frontiers in oncology 2022;12:983537
Frontiers in oncology 2022;12:983537
Phosphoproteomics reveals that cinobufotalin promotes intrahepatic cholangiocarcinoma cell apoptosis by activating the ATM/CHK2/p53 signaling pathway.
Xia Z, Li M, Hu M, Lin Y, Atteh LL, Fu W, Gao L, Bai M, Huang C, Yue P, Liu Y, Meng W
Frontiers in oncology 2022;12:982961
Frontiers in oncology 2022;12:982961
Irradiation enhances the malignancy-promoting behaviors of cancer-associated fibroblasts.
Zhang Z, Dong Y, Wu B, Li Y, Liu Z, Liu Z, Gao Y, Gao L, Song Q, Zheng Z, Yao Y
Frontiers in oncology 2022;12:965660
Frontiers in oncology 2022;12:965660
BI 2536 induces gasdermin E-dependent pyroptosis in ovarian cancer.
Huo J, Shen Y, Zhang Y, Shen L
Frontiers in oncology 2022;12:963928
Frontiers in oncology 2022;12:963928
Identification of necroptosis-related genes for predicting prognosis and exploring immune infiltration landscape in colon adenocarcinoma.
Wang Y, Lin MG, Meng L, Chen ZM, Wei ZJ, Ying SC, Xu A
Frontiers in oncology 2022;12:941156
Frontiers in oncology 2022;12:941156
The Novel LncRNA WASH5P Inhibits Colorectal Cancer Carcinogenesis via Targeting AKT Signaling Pathway.
Wei H, Mao T, Zhang Q, Ren K, Qi X, Zhang Y, Cao B, Jin Y, Tian Z, Ren L
Frontiers in oncology 2022;12:923425
Frontiers in oncology 2022;12:923425
Knockdown of USP8 inhibits prostate cancer cell growth, proliferation, and metastasis and promotes docetaxel's activity by suppressing the NF-kB signaling pathway.
Islam MT, Chen FZ, Chen HC, Wahid A
Frontiers in oncology 2022;12:923270
Frontiers in oncology 2022;12:923270
High Levels of DEAH-Box Helicases Relate to Poor Prognosis and Reduction of DHX9 Improves Radiosensitivity of Hepatocellular Carcinoma.
Chen X, Lin L, Chen G, Yan H, Li Z, Xiao M, He X, Zhang F, Zhang Y
Frontiers in oncology 2022;12:900671
Frontiers in oncology 2022;12:900671
SEMA3C Supports Pancreatic Cancer Progression by Regulating the Autophagy Process and Tumor Immune Microenvironment.
Zhang D, Lindstrom A, Kim EJ, Hwang CI, Hall ML, Lin TY, Li Y
Frontiers in oncology 2022;12:890154
Frontiers in oncology 2022;12:890154
ELOVLs Predict Distinct Prognosis Value and Immunotherapy Efficacy In Patients With Hepatocellular Carcinoma.
Zhang Y, Pang S, Sun B, Zhang M, Jiao X, Lai L, Qian Y, Yang N, Yang W
Frontiers in oncology 2022;12:884066
Frontiers in oncology 2022;12:884066
SETD3 Methyltransferase Regulates PLK1 Expression to Promote In Situ Hepatic Carcinogenesis.
Cheng M, Yang Q, Liu Y, Zhao MJ, Du X, Sun J, Shu WJ, Huang Z, Bi J, Xu X, Du HN
Frontiers in oncology 2022;12:882202
Frontiers in oncology 2022;12:882202
MOF negatively regulates estrogen receptor α signaling via CUL4B-mediated protein degradation in breast cancer.
Zhang X, Yang Y, Li D, Wu Z, Liu H, Zhao Z, Zhu H, Xie F, Li X
Frontiers in oncology 2022;12:868866
Frontiers in oncology 2022;12:868866
Mitochondrion-Localized SND1 Promotes Mitophagy and Liver Cancer Progression Through PGAM5.
Liang S, Zhu C, Suo C, Wei H, Yu Y, Gu X, Chen L, Yuan M, Shen S, Li S, Sun L, Gao P
Frontiers in oncology 2022;12:857968
Frontiers in oncology 2022;12:857968
Campylobacter jejuni Cytolethal Distending Toxin Induces GSDME-Dependent Pyroptosis in Colonic Epithelial Cells.
Gu J, Lin Y, Wang Z, Pan Q, Cai G, He Q, Xu X, Cai X
Frontiers in cellular and infection microbiology 2022;12:853204
Frontiers in cellular and infection microbiology 2022;12:853204
Vasoactive intestinal peptide-VIPR2 signaling regulates tumor cell migration.
Asano S, Yamasaka M, Ozasa K, Sakamoto K, Hayata-Takano A, Nakazawa T, Hashimoto H, Waschek JA, Ago Y
Frontiers in oncology 2022;12:852358
Frontiers in oncology 2022;12:852358
The CK1δ/ϵ-Tip60 Axis Enhances Wnt/β-Catenin Signaling via Regulating β-Catenin Acetylation in Colon Cancer.
Ning J, Sun Q, Su Z, Tan L, Tang Y, Sayed S, Li H, Xue VW, Liu S, Chen X, Lu D
Frontiers in oncology 2022;12:844477
Frontiers in oncology 2022;12:844477
MSLN Correlates With Immune Infiltration and Chemoresistance as a Prognostic Biomarker in Ovarian Cancer.
Li Y, Tian W, Zhang H, Zhang Z, Zhao Q, Chang L, Lei N, Zhang W
Frontiers in oncology 2022;12:830570
Frontiers in oncology 2022;12:830570
Inhibition of Angiogenesis and Extracellular Matrix Remodeling: Synergistic Effect of Renin-Angiotensin System Inhibitors and Bevacizumab.
Ren T, Jia H, Wu Q, Zhang Y, Ma Q, Yao D, Gao X, Xie D, Xu Z, Zhao Q, Zhang Y
Frontiers in oncology 2022;12:829059
Frontiers in oncology 2022;12:829059
Exosomal lncRNA LINC01356 Derived From Brain Metastatic Nonsmall-Cell Lung Cancer Cells Remodels the Blood-Brain Barrier.
Geng S, Tu S, Bai Z, Geng Y
Frontiers in oncology 2022;12:825899
Frontiers in oncology 2022;12:825899
ACADL Functions as a Tumor Suppressor in Hepatocellular Carcinoma Metastasis by Inhibiting Matrix Metalloproteinase 14.
Guo D, Zhang X, Cui H, Yu D, Zhang H, Shi X, Pang C, Li J, Guo W, Zhang S
Frontiers in oncology 2022;12:821484
Frontiers in oncology 2022;12:821484
Olaparib Induces RPL5/RPL11-Dependent p53 Activation via Nucleolar Stress.
Han T, Tong J, Wang M, Gan Y, Gao B, Chen J, Liu Y, Hao Q, Zhou X
Frontiers in oncology 2022;12:821366
Frontiers in oncology 2022;12:821366
LncRNA PELATON, a Ferroptosis Suppressor and Prognositic Signature for GBM.
Fu H, Zhang Z, Li D, Lv Q, Chen S, Zhang Z, Wu M
Frontiers in oncology 2022;12:817737
Frontiers in oncology 2022;12:817737
FUS-DDIT3 Fusion Oncoprotein Expression Affects JAK-STAT Signaling in Myxoid Liposarcoma.
Dolatabadi S, Jonasson E, Andersson L, Luna Santamaría M, Lindén M, Österlund T, Åman P, Ståhlberg A
Frontiers in oncology 2022;12:816894
Frontiers in oncology 2022;12:816894
TGF-β1-Mediated PD-L1 Glycosylation Contributes to Immune Escape via c-Jun/STT3A Pathway in Nasopharyngeal Carcinoma.
Ma XM, Luo YF, Zeng FF, Su C, Liu X, Li XP, Lu J
Frontiers in oncology 2022;12:815437
Frontiers in oncology 2022;12:815437
Identification of CFHR4 associated with poor prognosis of hepatocellular carcinoma.
Ding Q, Li H, Xu Z, Hu K, Ye Q
Frontiers in oncology 2022;12:812663
Frontiers in oncology 2022;12:812663
Lactobacillus rhamnosus GR-1 Alleviates Escherichia coli-Induced Inflammation via NF-κB and MAPKs Signaling in Bovine Endometrial Epithelial Cells.
Liu J, Feng X, Li B, Sun Y, Jin T, Feng M, Ni Y, Liu M
Frontiers in cellular and infection microbiology 2022;12:809674
Frontiers in cellular and infection microbiology 2022;12:809674
SRSF3 Expression Serves as a Potential Biomarker for Prognostic and Immune Response in Pan-Cancer.
Li Z, Huang H, Wu X, Yu T, Xiao F, Zhou H, Shang A, Yang Y
Frontiers in oncology 2022;12:808530
Frontiers in oncology 2022;12:808530
RPS3 Promotes the Metastasis and Cisplatin Resistance of Adenoid Cystic Carcinoma.
Rui X, Huang Z, Chen R, Chen Y, Wang Y, Huang Z
Frontiers in oncology 2022;12:804439
Frontiers in oncology 2022;12:804439
Low Level of PALMD Contributes to the Metastasis of Uveal Melanoma.
Cai MY, Xu YL, Rong H, Yang H
Frontiers in oncology 2022;12:802941
Frontiers in oncology 2022;12:802941
Thymidine Kinase 1 Drives Skin Cutaneous Melanoma Malignant Progression and Metabolic Reprogramming.
Zuo S, Wang H, Li L, Pan H, Lu L
Frontiers in oncology 2022;12:802807
Frontiers in oncology 2022;12:802807
Identification of LncRNA Prognostic Signature Associated With Genomic Instability in Pancreatic Adenocarcinoma.
Zhu J, Huang Q, Peng X, Luo C, Liu S, Liu Z, Wu X, Luo H
Frontiers in oncology 2022;12:799475
Frontiers in oncology 2022;12:799475
Comprehensive Analysis of the PRDXs Family in Head and Neck Squamous Cell Carcinoma.
Cao R, Zhang W, Zhang H, Wang L, Chen X, Ren X, Cheng B, Xia J
Frontiers in oncology 2022;12:798483
Frontiers in oncology 2022;12:798483
Phase II Study of Gemcitabine, Peg-Asparaginase, Dexamethasone and Methotrexate Regimen for Newly Diagnosed Extranodal Natural Killer/T-Cell Lymphoma, Nasal Type: Final Analysis With Long-Term Follow-Up and Rational Research for the Combination.
Wang Y, Wang CQ, Sun P, Liu PP, Yang H, Wang HY, Rao HL, Li S, Jiang WQ, Huang JJ, Li ZM
Frontiers in oncology 2022;12:796738
Frontiers in oncology 2022;12:796738
Distinct Roles of m(5)C RNA Methyltransferase NSUN2 in Major Gynecologic Cancers.
Wang L, Zhang J, Su Y, Maimaitiyiming Y, Yang S, Shen Z, Lin S, Shen S, Zhan G, Wang F, Hsu CH, Cheng X
Frontiers in oncology 2022;12:786266
Frontiers in oncology 2022;12:786266
CDC27-ODC1 Axis Promotes Metastasis, Accelerates Ferroptosis and Predicts Poor Prognosis in Neuroblastoma.
Qiu L, Zhou R, Luo Z, Wu J, Jiang H
Frontiers in oncology 2022;12:774458
Frontiers in oncology 2022;12:774458
ASB17 Facilitates the Burst of LPS-Induced Inflammation Through Maintaining TRAF6 Stability.
Wan P, Yang G, Zhang S, Zhang Y, Jia Y, Che X, Luo Z, Pan P, Li G, Chen X, Zhang Q, Zhang W, Tan Q, Li Y, Wu J
Frontiers in cellular and infection microbiology 2022;12:759077
Frontiers in cellular and infection microbiology 2022;12:759077
N-Glycosylation at Asn291 Stabilizes TIM-4 and Promotes the Metastasis of NSCLC.
Chen S, Wang Y, Liu W, Liang Y, Wang Y, Wu Z, Xu L, Liang X, Ma C, Gao L
Frontiers in oncology 2022;12:730530
Frontiers in oncology 2022;12:730530
HRK inhibits colorectal cancer cells proliferation by suppressing the PI3K/AKT/mTOR pathway.
Wang H, Chen Y, Yuan Q, Chen L, Dai P, Li X
Frontiers in oncology 2022;12:1053510
Frontiers in oncology 2022;12:1053510
IGF2BP3 promotes progression of gallbladder carcinoma by stabilizing KLK5 mRNA in N(6)-methyladenosine-dependent binding.
Zhang J, Yang K, Bu J, Yan J, Hu X, Liu K, Gao S, Tang S, Gao L, Chen W
Frontiers in oncology 2022;12:1035871
Frontiers in oncology 2022;12:1035871
Weighted gene co-expression network reveals driver genes contributing to phenotypes of anaplastic thyroid carcinoma and immune checkpoint identification for therapeutic targets.
Dong X, Yang Y, Hou J, Chen W, Yuan Q, Xu G, Liu J, Li C, Wu G
Frontiers in oncology 2022;12:1018479
Frontiers in oncology 2022;12:1018479
CXCL10-armed oncolytic adenovirus promotes tumor-infiltrating T-cell chemotaxis to enhance anti-PD-1 therapy.
Li X, Lu M, Yuan M, Ye J, Zhang W, Xu L, Wu X, Hui B, Yang Y, Wei B, Guo C, Wei M, Dong J, Wu X, Gu Y
Oncoimmunology 2022;11(1):2118210
Oncoimmunology 2022;11(1):2118210
MerTK-mediated efferocytosis promotes immune tolerance and tumor progression in osteosarcoma through enhancing M2 polarization and PD-L1 expression.
Lin J, Xu A, Jin J, Zhang M, Lou J, Qian C, Zhu J, Wang Y, Yang Z, Li X, Yu W, Liu B, Tao H
Oncoimmunology 2022;11(1):2024941
Oncoimmunology 2022;11(1):2024941
Control of fibrosis and hypertrophic scar formation via glycolysis regulation with IR780.
Meng X, Yu Z, Xu W, Chai J, Fang S, Min P, Chen Y, Zhang Y, Zhang Z
Burns & trauma 2022;10:tkac015
Burns & trauma 2022;10:tkac015
M1 macrophage-derived extracellular vesicle containing tsRNA-5006c promotes osteogenic differentiation of aortic valve interstitial cells through regulating mitophagy.
Xia H, Gao M, Chen J, Huang G, Xiang X, Wang Y, Huang Z, Li Y, Su S, Zhao Z, Zeng Q, Ruan Y
PeerJ 2022;10:e14307
PeerJ 2022;10:e14307
Ac2-26 attenuates hepatic ischemia-reperfusion injury in mice via regulating IL-22/IL-22R1/STAT3 signaling.
Li W, Jiang H, Bai C, Yu S, Pan Y, Wang C, Li H, Li M, Sheng Y, Chu F, Wang J, Chen Y, Li J, Jiang J
PeerJ 2022;10:e14086
PeerJ 2022;10:e14086
SERBP1 affects the apoptotic level by regulating the expression and alternative splicing of cellular and metabolic process genes in HeLa cells.
Zhou J, Chen W, He Q, Chen D, Li C, Jiang C, Ding Z, Qian Q
PeerJ 2022;10:e14084
PeerJ 2022;10:e14084
Identification and validation of immune related core transcription factors GTF2I in NAFLD.
Zhang M, Zhang Y, Jiao X, Lai L, Qian Y, Sun B, Yang W
PeerJ 2022;10:e13735
PeerJ 2022;10:e13735
Ferroptotic cardiomyocyte-derived exosomes promote cardiac macrophage M1 polarization during myocardial infarction.
Sun S, Wu Y, Maimaitijiang A, Huang Q, Chen Q
PeerJ 2022;10:e13717
PeerJ 2022;10:e13717
WASH regulates the oxidative stress Nrf2/ARE pathway to inhibit proliferation and promote apoptosis of HeLa cells under the action of Jolkinolide B.
Hong Y, Liu J, Kong W, Li H, Cui Y, Liu Y, Deng Z, Ma D, Zhang K, Li J, Li M
PeerJ 2022;10:e13499
PeerJ 2022;10:e13499
Transcriptome changes in ERGIC3-knockdown hepatocellular carcinoma cells: ERGIC3 is a novel immune function related gene.
Liu M, Zhao Q, Zheng X, Yang L, Zhao Y, Li X, Wu M
PeerJ 2022;10:e13369
PeerJ 2022;10:e13369
Glucocorticoids induce osteonecrosis of the femoral head in rats via PI3K/AKT/FOXO1 signaling pathway.
Sun F, Zhou JL, Wei SX, Jiang ZW, Peng H
PeerJ 2022;10:e13319
PeerJ 2022;10:e13319
A long noncoding RNA GTF2IRD2P1 suppresses cell proliferation in bladder cancer by inhibiting the Wnt/β‑catenin signaling pathway.
Huang Z, Gao H, Qing L, Wang B, He C, Luo N, Lu C, Fan S, Gu P, Zhao H
PeerJ 2022;10:e13220
PeerJ 2022;10:e13220
Protection of catalpol against triptolide-induced hepatotoxicity by inhibiting excessive autophagy via the PERK-ATF4-CHOP pathway.
Zhang L, Li C, Fu L, Yu Z, Xu G, Zhou J, Shen M, Feng Z, Zhu H, Xie T, Zhou L, Zhou X
PeerJ 2022;10:e12759
PeerJ 2022;10:e12759
Targeting EIF3C to suppress the development and progression of nasopharyngeal carcinoma.
Zhao Q, Luo X, Li H, Bai Y, Chen Q, Yang M, Pei B, Xu C, Han S
Frontiers in bioengineering and biotechnology 2022;10:994628
Frontiers in bioengineering and biotechnology 2022;10:994628
P14AS upregulates gene expression in the CDKN2A/2B locus through competitive binding to PcG protein CBX7.
Li Z, Qiao J, Ma W, Zhou J, Gu L, Deng D, Zhang B
Frontiers in cell and developmental biology 2022;10:993525
Frontiers in cell and developmental biology 2022;10:993525
The SNARE protein Vti1b is recruited to the sites of BCR activation but is redundant for antigen internalisation, processing and presentation.
Music A, Tejeda-González B, Cunha DM, Fischer von Mollard G, Hernández-Pérez S, Mattila PK
Frontiers in cell and developmental biology 2022;10:987148
Frontiers in cell and developmental biology 2022;10:987148
Rictor maintains endothelial integrity under shear stress.
Li H, Zhou WY, Liu YX, Xia YY, Xia CL, Pan DR, Li Z, Shi Y, Chen SL, Zhang JX
Frontiers in cell and developmental biology 2022;10:963866
Frontiers in cell and developmental biology 2022;10:963866
The proneural transcription factor ASCL1 regulates cell proliferation and primes for differentiation in neuroblastoma.
Parkinson LM, Gillen SL, Woods LM, Chaytor L, Marcos D, Ali FR, Carroll JS, Philpott A
Frontiers in cell and developmental biology 2022;10:942579
Frontiers in cell and developmental biology 2022;10:942579
Upregulated ENC1 predicts unfavorable prognosis and correlates with immune infiltration in endometrial cancer.
He L, He W, Luo J, Xu M
Frontiers in cell and developmental biology 2022;10:919637
Frontiers in cell and developmental biology 2022;10:919637
Primary Repair for Treating Acute Proximal Anterior Cruciate Ligament Tears: A Histological Analysis and Prospective Clinical Trial.
Yang Y, Jin Z, Luo J, Zhang D, Shen P, Zheng D, Liu D, Bai L
Frontiers in bioengineering and biotechnology 2022;10:913900
Frontiers in bioengineering and biotechnology 2022;10:913900
ARPC2: A Pan-Cancer Prognostic and Immunological Biomarker That Promotes Hepatocellular Carcinoma Cell Proliferation and Invasion.
Huang S, Dong C, Li D, Xu Y, Wu J
Frontiers in cell and developmental biology 2022;10:896080
Frontiers in cell and developmental biology 2022;10:896080
Gender Differential Expression of AR/miR-21 Signaling Axis and Its Protective Effect on Renal Ischemia-Reperfusion Injury.
Huang G, Yao Q, Ye Z, Huang Y, Zhang C, Jiang Y, Xi X
Frontiers in cell and developmental biology 2022;10:861327
Frontiers in cell and developmental biology 2022;10:861327
CRISPR-Cas13-Mediated Knockdown of Regulator of G-Protein Signaling 8 (RGS8) Does Not Affect Purkinje Cell Dendritic Development.
Wu QW, Kapfhammer JP
Frontiers in cell and developmental biology 2022;10:854273
Frontiers in cell and developmental biology 2022;10:854273
Deacetylation of YAP1 Promotes the Resistance to Chemo- and Targeted Therapy in FLT3-ITD(+) AML Cells.
Feng P, Zhang J, Zhang J, Liu X, Pan L, Chen D, Ji M, Lu F, Li P, Li G, Sun T, Li J, Ye J, Ji C
Frontiers in cell and developmental biology 2022;10:842214
Frontiers in cell and developmental biology 2022;10:842214
HSPA6 is Correlated With the Malignant Progression and Immune Microenvironment of Gliomas.
Zhou X, Ji Q, Li Q, Wang P, Hu G, Xiao F, Ye M, Lin L, Luo M, Guo Y, Wu W, Huang K, Guo H
Frontiers in cell and developmental biology 2022;10:833938
Frontiers in cell and developmental biology 2022;10:833938
Differential Degradation of TRA2A and PYCR2 Mediated by Ubiquitin E3 Ligase E4B.
Lu Y, Jiang B, Peng K, Li S, Liu X, Wang B, Chen Y, Wang T, Zhao B
Frontiers in cell and developmental biology 2022;10:833396
Frontiers in cell and developmental biology 2022;10:833396
Theaflavin Attenuates TBHP-Induced Endothelial Cells Oxidative Stress by Activating PI3K/AKT/Nrf2 and Accelerates Wound Healing in Rats.
Chen D, Wu Z, Wu LN, Jiang J, Hu GN
Frontiers in bioengineering and biotechnology 2022;10:830574
Frontiers in bioengineering and biotechnology 2022;10:830574
Hesperidin Ameliorates Dexamethasone-Induced Osteoporosis by Inhibiting p53.
Zhang M, Chen D, Zeng N, Liu Z, Chen X, Xiao H, Xiao L, Liu Z, Dong Y, Zheng J
Frontiers in cell and developmental biology 2022;10:820922
Frontiers in cell and developmental biology 2022;10:820922
ITGAL as a Prognostic Biomarker Correlated With Immune Infiltrates in Gastric Cancer.
Zhang J, Wang H, Yuan C, Wu J, Xu J, Chen S, Zhang C, He Y
Frontiers in cell and developmental biology 2022;10:808212
Frontiers in cell and developmental biology 2022;10:808212
Biomimetic Metal-Organic Framework Nanoparticles for Synergistic Combining of SDT-Chemotherapy Induce Pyroptosis in Gastric Cancer.
Yu Z, Cao W, Han C, Wang Z, Qiu Y, Wang J, Wei M, Wang J, Zhang S, Liu S, Mo S, Chen J
Frontiers in bioengineering and biotechnology 2022;10:796820
Frontiers in bioengineering and biotechnology 2022;10:796820
Hyaluronic Acid Facilitates Angiogenesis of Endothelial Colony Forming Cell Combining With Mesenchymal Stem Cell via CD44/ MicroRNA-139-5p Pathway.
Luo Y, Liang F, Wan X, Liu S, Fu L, Mo J, Meng X, Mo Z
Frontiers in bioengineering and biotechnology 2022;10:794037
Frontiers in bioengineering and biotechnology 2022;10:794037
Endoplasmic Reticulum Stress Is Involved in Muscular Pathogenesis in Idiopathic Inflammatory Myopathies.
Ma X, Gao HJ, Zhang Q, Yang MG, Bi ZJ, Ji SQ, Li Y, Xu L, Bu BT
Frontiers in cell and developmental biology 2022;10:791986
Frontiers in cell and developmental biology 2022;10:791986
Development of Tumor Mutation Burden-Related Prognostic Model and Novel Biomarker Identification in Stomach Adenocarcinoma.
Fu M, Huang Y, Peng X, Li X, Luo N, Zhu W, Yang F, Chen Z, Ma S, Zhang Y, Li Q, Hu G
Frontiers in cell and developmental biology 2022;10:790920
Frontiers in cell and developmental biology 2022;10:790920
H19 Promotes Osteoblastic Transition by Acting as ceRNA of miR-140-5p in Vascular Smooth Muscle Cells.
Xu F, Zhong JY, Guo B, Lin X, Wu F, Li FX, Shan SK, Zheng MH, Wang Y, Xu QS, Lei LM, Tan CM, Liao XB, Yuan LQ
Frontiers in cell and developmental biology 2022;10:774363
Frontiers in cell and developmental biology 2022;10:774363
Chitosan degradation products promote healing of burn wounds of rat skin.
Zhang C, Zhang Q, Yang D, Qiao Y, Wang B, Yan J, Li Z, Huang Z, Zhou Y, Hu K, Zhang Y
Frontiers in bioengineering and biotechnology 2022;10:1002437
Frontiers in bioengineering and biotechnology 2022;10:1002437
Metformin carbon nanodots promote odontoblastic differentiation of dental pulp stem cells by pathway of autophagy.
Lu J, Li R, Ni S, Xie Y, Liu X, Zhang K, Li Y
Frontiers in bioengineering and biotechnology 2022;10:1002291
Frontiers in bioengineering and biotechnology 2022;10:1002291
PKC signal amplification suppresses non-small cell lung cancer growth by promoting p21 expression and phosphorylation.
Liu S, Zhang Y, Yang Q, Zhang Y, Liu H, Huang MH, Wang R, Lu F
Heliyon 2022 Sep;8(9):e10657
Heliyon 2022 Sep;8(9):e10657
An EPO-loaded multifunctional hydrogel synergizing with adipose-derived stem cells restores neurogenic erectile function via enhancing nerve regeneration and penile rehabilitation.
Shao J, Nie P, Yang W, Guo R, Ding D, Liang R, Wei B, Wei H
Bioengineering & translational medicine 2022 Sep;7(3):e10319
Bioengineering & translational medicine 2022 Sep;7(3):e10319
HSPA5 repressed ferroptosis to promote colorectal cancer development by maintaining GPX4 stability.
Wang R, Hua L, Ma P, Song Y, Min J, Guo Y, Yang C, Li J, Su H
Neoplasma 2022 Sep;69(5):1054-1069
Neoplasma 2022 Sep;69(5):1054-1069
lncKRT16P6 promotes tongue squamous cell carcinoma progression by sponging miR‑3180 and regulating GATAD2A expression.
Zhang M, Wu L, Wang X, Chen J
International journal of oncology 2022 Sep;61(3)
International journal of oncology 2022 Sep;61(3)
Cerebral small vessel disease caused by PLOD3 mutation: Expanding the phenotypic spectrum of lysyl hydroxylase-3 deficiency.
Zhou J, Feng W, Zhuo X, Lu W, Wang J, Fang F, Wang X
Pediatric investigation 2022 Sep;6(3):219-223
Pediatric investigation 2022 Sep;6(3):219-223
Inhibitory effects of cedar pine needle extract on H9N2 avian influenza virus in vitro and in vivo.
Han M, Gao S, Hu W, Zhou Q, Li H, Lin W, Chen F
Virology 2022 Sep;574:25-36
Virology 2022 Sep;574:25-36
The caspase-1 inhibitor VX765 upregulates connexin 43 expression and improves cell-cell communication after myocardial infarction via suppressing the IL-1β/p38 MAPK pathway.
Su XL, Wang SH, Komal S, Cui LG, Ni RC, Zhang LR, Han SN
Acta pharmacologica Sinica 2022 Sep;43(9):2289-2301
Acta pharmacologica Sinica 2022 Sep;43(9):2289-2301
Patchouli alcohol as a selective estrogen receptor β agonist ameliorates AD-like pathology of APP/PS1 model mice.
Yan QY, Lv JL, Shen XY, Ou-Yang XN, Yang JZ, Nie RF, Lu J, Huang YJ, Wang JY, Shen X
Acta pharmacologica Sinica 2022 Sep;43(9):2226-2241
Acta pharmacologica Sinica 2022 Sep;43(9):2226-2241
FumDSB can alleviate the inflammatory response induced by fumonisin B(1) in growing pigs.
Liu Q, Huang L, Cui Z, Qiao B, Li F, Wang C
Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment 2022 Sep;39(9):1619-1633
Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment 2022 Sep;39(9):1619-1633
YAP knockdown in combination with ferroptosis induction increases the sensitivity of HOS human osteosarcoma cells to pyropheophorbide-α methyl ester-mediated photodynamic therapy.
Zhan F, Zhang Y, Zuo Q, Xie C, Li H, Tian L, Wu C, Chen Z, Yang C, Wang Y, Li Q, He T, Yu H, Chen J, Xiang J, Ou Y
Photodiagnosis and photodynamic therapy 2022 Sep;39:102964
Photodiagnosis and photodynamic therapy 2022 Sep;39:102964
Small extracellular vesicles derived from PD-L1-modified mesenchymal stem cell promote Tregs differentiation and prolong allograft survival.
Ou Q, Dou X, Tang J, Wu P, Pan D
Cell and tissue research 2022 Sep;389(3):465-481
Cell and tissue research 2022 Sep;389(3):465-481
Fine Particulate Matter Triggers α-Synuclein Fibrillization and Parkinson-like Neurodegeneration.
Yuan X, Yang Y, Liu C, Tian Y, Xia D, Liu Z, Pan L, Xiong M, Xiong J, Meng L, Zhang Z, Ye K, Jiang H, Zhang Z
Movement disorders : official journal of the Movement Disorder Society 2022 Sep;37(9):1817-1830
Movement disorders : official journal of the Movement Disorder Society 2022 Sep;37(9):1817-1830
FUS aggregation following ischemic stroke favors brain astrocyte activation through inducing excessive autophagy.
Wu S, Yin Y, Du L
Experimental neurology 2022 Sep;355:114144
Experimental neurology 2022 Sep;355:114144
TMEM97 is transcriptionally activated by YY1 and promotes colorectal cancer progression via the GSK-3β/β-catenin signaling pathway.
Mao D, Zhang X, Wang Z, Xu G, Zhang Y
Human cell 2022 Sep;35(5):1535-1546
Human cell 2022 Sep;35(5):1535-1546
RhoGDI1 interacts with PHLDA2, suppresses the proliferation, migration, and invasion of trophoblast cells, and participates in the pathogenesis of preeclampsia.
Song G, Jin F
Human cell 2022 Sep;35(5):1440-1452
Human cell 2022 Sep;35(5):1440-1452
Glutamate drives 'local Ca(2+) release' in cardiac pacemaker cells.
Xie D, Xiong K, Su X, Wang G, Zou Q, Wang L, Zhang C, Cao Y, Shao B, Zhang Y, Zhang P, Liang D, Liu Y, Chen YH
Cell research 2022 Sep;32(9):843-854
Cell research 2022 Sep;32(9):843-854
G protein-coupled receptor kinase phosphorylation of distal C-tail sites specifies βarrestin1-mediated signaling by chemokine receptor CXCR4.
Zhuo Y, Crecelius JM, Marchese A
The Journal of biological chemistry 2022 Sep;298(9):102351
The Journal of biological chemistry 2022 Sep;298(9):102351
Progranulin-derived granulin E and lysosome membrane protein CD68 interact to reciprocally regulate their protein homeostasis.
Santos MN, Paushter DH, Zhang T, Wu X, Feng T, Lou J, Du H, Becker SM, Fragoza R, Yu H, Hu F
The Journal of biological chemistry 2022 Sep;298(9):102348
The Journal of biological chemistry 2022 Sep;298(9):102348
Induction of zinc finger protein RNF6 auto-ubiquitination for the treatment of myeloma and chronic myeloid leukemia.
Zhuang H, Ren Y, Mao C, Zhong Y, Zhang Z, Cao B, Zhang Y, Huang J, Xu G, Huang Z, Xu Y, Mao X
The Journal of biological chemistry 2022 Sep;298(9):102314
The Journal of biological chemistry 2022 Sep;298(9):102314
Inhibition of cGAS-STING by JQ1 alleviates oxidative stress-induced retina inflammation and degeneration.
Zou M, Ke Q, Nie Q, Qi R, Zhu X, Liu W, Hu X, Sun Q, Fu JL, Tang X, Liu Y, Li DW, Gong L
Cell death and differentiation 2022 Sep;29(9):1816-1833
Cell death and differentiation 2022 Sep;29(9):1816-1833
Valosin-containing protein (VCP/p97) is responsible for the endocytotic trafficking of classical swine fever virus.
Sun RC, Hu JH, Li XH, Liu CC, Liu YY, Chen J, Yang YC, Zhou B
Veterinary microbiology 2022 Sep;272:109511
Veterinary microbiology 2022 Sep;272:109511
Circulating cell-free mtDNA release is associated with the activation of cGAS-STING pathway and inflammation in mitochondrial diseases.
Zhao X, Yu M, Zhao Y, Zheng Y, Meng L, Du K, Xie Z, Lv H, Zhang W, Liu J, Wang Q, Yuan Y, Wang Z, Deng J
Journal of neurology 2022 Sep;269(9):4985-4996
Journal of neurology 2022 Sep;269(9):4985-4996
Rare variants in GABRG2 associated with sleep-related hypermotor epilepsy.
Jiang YL, Song CG, Zhou HM, Feng B, Zhao JJ, Liu Y, Man YL, Han J, Liu SB, Jiang W
Journal of neurology 2022 Sep;269(9):4939-4954
Journal of neurology 2022 Sep;269(9):4939-4954
Rare pathogenic variants in WNK3 cause X-linked intellectual disability.
Küry S, Zhang J, Besnard T, Caro-Llopis A, Zeng X, Robert SM, Josiah SS, Kiziltug E, Denommé-Pichon AS, Cogné B, Kundishora AJ, Hao LT, Li H, Stevenson RE, Louie RJ, Deb W, Torti E, Vignard V, McWalter K, Raymond FL, Rajabi F, Ranza E, Grozeva D, Coury SA, Blanc X, Brischoux-Boucher E, Keren B, Õunap K, Reinson K, Ilves P, Wentzensen IM, Barr EE, Guihard SH, Charles P, Seaby EG, Monaghan KG, Rio M, van Bever Y, van Slegtenhorst M, Chung WK, Wilson A, Quinquis D, Bréhéret F, Retterer K, Lindenbaum P, Scalais E, Rhodes L, Stouffs K, Pereira EM, Berger SM, Milla SS, Jaykumar AB, Cobb MH, Panchagnula S, Duy PQ, Vincent M, Mercier S, Gilbert-Dussardier B, Le Guillou X, Audebert-Bellanger S, Odent S, Schmitt S, Boisseau P, Bonneau D, Toutain A, Colin E, Pasquier L, Redon R, Bouman A, Rosenfeld JA, Friez MJ, Pérez-Peña H, Akhtar Rizvi SR, Haider S, Antonarakis SE, Schwartz CE, Martínez F, Bézieau S, Kahle KT, Isidor B
Genetics in medicine : official journal of the American College of Medical Genetics 2022 Sep;24(9):1941-1951
Genetics in medicine : official journal of the American College of Medical Genetics 2022 Sep;24(9):1941-1951
Sevoflurane exposure during the second trimester induces neurotoxicity in offspring rats by hyperactivation of PARP-1.
Wang C, Jiang Q, Zhao P
Psychopharmacology 2022 Sep;239(9):3031-3045
Psychopharmacology 2022 Sep;239(9):3031-3045
CircFAT1 regulates retinal pigment epithelial cell pyroptosis and autophagy via mediating m6A reader protein YTHDF2 expression in diabetic retinopathy.
Huang C, Qi P, Cui H, Lu Q, Gao X
Experimental eye research 2022 Sep;222:109152
Experimental eye research 2022 Sep;222:109152
Chronological attenuation of NPRA/PKG/AMPK signaling promotes vascular aging and elevates blood pressure.
Long C, Liu H, Zhan W, Chen L, Yu Z, Tian S, Xiang Y, Chen S, Tian XL
Aging cell 2022 Sep;21(9):e13699
Aging cell 2022 Sep;21(9):e13699
MiR-200b-3p is upregulated in the placental tissues from patients with preeclampsia and promotes the development of preeclampsia via targeting profilin 2.
Liu H, Wang X
Cell cycle (Georgetown, Tex.) 2022 Sep;21(18):1945-1957
Cell cycle (Georgetown, Tex.) 2022 Sep;21(18):1945-1957
MYC as a therapeutic target for the treatment of triple-negative breast cancer: preclinical investigations with the novel MYC inhibitor, MYCi975.
Tang M, O'Grady S, Crown J, Duffy MJ
Breast cancer research and treatment 2022 Sep;195(2):105-115
Breast cancer research and treatment 2022 Sep;195(2):105-115
Type I collagen reduces lipid accumulation during adipogenesis of preadipocytes 3T3-L1 via the YAP-mTOR-autophagy axis.
Gao Y, Ma K, Kang Y, Liu W, Liu X, Long X, Hayashi T, Hattori S, Mizuno K, Fujisaki H, Ikejima T
Biochimica et biophysica acta. Molecular and cell biology of lipids 2022 Sep;1867(9):159181
Biochimica et biophysica acta. Molecular and cell biology of lipids 2022 Sep;1867(9):159181
HAP1 interacts with 14-3-3 to regulate epileptic seizure via GABA(A)R-mediated inhibitory synaptic transmission in pentylenetetrazole rat model.
Wen Y, Zhang G, Liu L, Zhang P, Lin L, Mei R, Zhang F, Chen Y, Li R
Neuroscience research 2022 Sep;182:7-14
Neuroscience research 2022 Sep;182:7-14
Outer membrane vesicles derived from heatstroke-associated intestinal microbiota promote multiple organ injury in mice.
Li Y, Li H, Tong H, Maegelev M, Gu Z
Microbial pathogenesis 2022 Sep;170:105653
Microbial pathogenesis 2022 Sep;170:105653
MicroRNA-223 downregulation promotes HBx-induced podocyte pyroptosis by targeting the NLRP3 inflammasome.
Yu Y, Dong H, Zhang Y, Sun J, Li B, Chen Y, Feng M, Yang X, Gao S, Jiang W
Archives of virology 2022 Sep;167(9):1841-1854
Archives of virology 2022 Sep;167(9):1841-1854
CHRNA1 induces sarcopenia through neuromuscular synaptic elimination.
Liao Z, Xiao M, Chen J, Yang Y, Lyu Q, Zhou J, Sun Y, Zhao Y, Fan Z, Yu J, Wu Y, Chen Q, Wu J, Xiao Q
Experimental gerontology 2022 Sep;166:111891
Experimental gerontology 2022 Sep;166:111891
Colchicine improves severe acute pancreatitis-induced acute lung injury by suppressing inflammation, apoptosis and oxidative stress in rats.
Zhang D, Li L, Li J, Wei Y, Tang J, Man X, Liu F
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Sep;153:113461
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Sep;153:113461
Allantoin ameliorates amyloid β-peptide-induced memory impairment by regulating the PI3K/Akt/GSK-3β signaling pathway in rats.
Tzeng CY, Lee WS, Liu KF, Tsou HK, Chen CJ, Peng WH, Tsai JC
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Sep;153:113389
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Sep;153:113389
Hypouricemic effect of 2,4-dihydroxybenzoic acid methyl ester in hyperuricemic mice through inhibiting XOD and down-regulating URAT1.
Yong T, Liang D, Xiao C, Huang L, Chen S, Xie Y, Gao X, Wu Q, Hu H, Li X, Liu Y, Cai M
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Sep;153:113303
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Sep;153:113303
ATF4 protects against sorafenib-induced cardiotoxicity by suppressing ferroptosis.
Jiang H, Wang C, Zhang A, Li Y, Li J, Li Z, Yang X, Hou Y
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Sep;153:113280
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Sep;153:113280
Injectable cartilage matrix hydrogel loaded with cartilage endplate stem cells engineered to release exosomes for non-invasive treatment of intervertebral disc degeneration.
Luo L, Gong J, Wang Z, Liu Y, Cao J, Qin J, Zuo R, Zhang H, Wang S, Zhao P, Yang D, Zhang M, Wang Y, Zhang J, Zhou Y, Li C, Ni B, Tian Z, Liu M
Bioactive materials 2022 Sep;15:29-43
Bioactive materials 2022 Sep;15:29-43
Neutrophil extracellular traps induced by Porphyromonas gingivalis lipopolysaccharide modulate inflammatory responses via a Ca(2+)-dependent pathway.
Chen JL, Tong Y, Zhu Q, Gao LQ, Sun Y
Archives of oral biology 2022 Sep;141:105467
Archives of oral biology 2022 Sep;141:105467
Compromised glycolysis contributes to foot process fusion of podocytes in diabetic kidney disease: Role of ornithine catabolism.
Luo Q, Liang W, Zhang Z, Zhu Z, Chen Z, Hu J, Yang K, Chi Q, Ding G
Metabolism: clinical and experimental 2022 Sep;134:155245
Metabolism: clinical and experimental 2022 Sep;134:155245
TMEM92 acts as an immune-resistance and prognostic marker in pancreatic cancer from the perspective of predictive, preventive, and personalized medicine.
Zhang S, Wan X, Lv M, Li C, Chu Q, Wang G
The EPMA journal 2022 Sep;13(3):519-534
The EPMA journal 2022 Sep;13(3):519-534
Identifying potential signatures for atherosclerosis in the context of predictive, preventive, and personalized medicine using integrative bioinformatics approaches and machine-learning strategies.
Xu J, Zhou H, Cheng Y, Xiang G
The EPMA journal 2022 Sep;13(3):433-449
The EPMA journal 2022 Sep;13(3):433-449
Design, semi-synthesis and bioactivity evaluation of novel podophyllotoxin derivatives as potent anti-tumor agents.
Sun W, Sun F, Meng J, Cao X, Zhao S, Wang C, Li L, Jiang P
Bioorganic chemistry 2022 Sep;126:105906
Bioorganic chemistry 2022 Sep;126:105906
SGLT2 inhibitor, canagliflozin, ameliorates cardiac inflammation in experimental autoimmune myocarditis.
Long Q, Li L, Yang H, Lu Y, Yang H, Zhu Y, Tang Y, Liu C, Yuan J
International immunopharmacology 2022 Sep;110:109024
International immunopharmacology 2022 Sep;110:109024
Angiotensin II type 2 receptor pharmacological agonist, C21, reduces the inflammation and pain hypersensitivity in mice with joint inflammatory pain.
Gao W, Shen L, Long DD, Pan TT, Wang D, Chai XQ, Hu SS
International immunopharmacology 2022 Sep;110:108921
International immunopharmacology 2022 Sep;110:108921
PTS is activated by ATF4 and promotes lung adenocarcinoma development via the Wnt pathway.
Ma W, Wang C, Li R, Han Z, Jiang Y, Zhang X, Divisi D, Capobianco E, Zhang L, Dong W
Translational lung cancer research 2022 Sep;11(9):1912-1925
Translational lung cancer research 2022 Sep;11(9):1912-1925
Kynurenine metabolism is altered in mdx mice: a potential muscle to brain connection.
Copeland EN, Watson CJF, Whitley KC, Baranowski BJ, Kurgan N, MacNeil AJ, MacPherson REK, Fajardo VA, Allison DJ
Experimental physiology 2022 Sep;107(9):1029-1036
Experimental physiology 2022 Sep;107(9):1029-1036
ΔNp63α mediates sulforaphane suppressed colorectal cancer stem cell properties through transcriptional regulation of Nanog/Oct4/Sox2.
Chen Y, Wang MH, Wu JY, Zhu JY, Xie CF, Li XT, Wu JS, Geng SS, Li YD, Han HY, Zhong CY
The Journal of nutritional biochemistry 2022 Sep;107:109067
The Journal of nutritional biochemistry 2022 Sep;107:109067
Targeting p65 to inhibit Cas3 transcription by Onjisaponin B for radiation damage therapy in p65+/- mice.
Wang TY, Hu YJ, Wang X, Li YF, Zhang F, Yan YD, Dou WT, Cheng CY, Xu P
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Sep;104:154317
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Sep;104:154317
Huoxin pill prevents excessive inflammation and cardiac dysfunction following myocardial infarction by inhibiting adverse Wnt/β‑catenin signaling activation.
He J, Wo D, Ma E, Wang Q, Chen J, Gao Q, Zhao Q, Shen F, Peng J, Zhu W, Ren DN
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Sep;104:154293
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Sep;104:154293
Tetrahydrocurcumin improves lipopolysaccharide-induced myocardial dysfunction by inhibiting oxidative stress and inflammation via JNK/ERK signaling pathway regulation.
Zhu H, Zhang L, Jia H, Xu L, Cao Y, Zhai M, Li K, Xia L, Jiang L, Li X, Zhou Y, Liu J, Yu S, Duan W
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Sep;104:154283
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Sep;104:154283
Celastrol upregulated ATG7 triggers autophagy via targeting Nur77 in colorectal cancer.
Zhang W, Wu Z, Qi H, Chen L, Wang T, Mao X, Shi H, Chen H, Zhong M, Shi X, Wang X, Li Q
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Sep;104:154280
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Sep;104:154280
Enhancer of zeste homolog 2 exerts functions in gastric cancer development via modulating microRNA-222-3p methylation and WEE1 expression.
Feng Y, Wang C, Shi T, Liu W, Liu H, Zhu B, Gao F
Chemical biology & drug design 2022 Sep;100(3):320-333
Chemical biology & drug design 2022 Sep;100(3):320-333
Mannose inhibits the growth of prostate cancer through a mitochondrial mechanism.
Deng YL, Liu R, Cai ZD, Han ZD, Feng YF, Cai SH, Chen QB, Zhu JG, Zhong WD
Asian journal of andrology 2022 Sep-Oct;24(5):540-548
Asian journal of andrology 2022 Sep-Oct;24(5):540-548
Human TRUB1 is a highly conserved pseudouridine synthase responsible for the formation of Ψ55 in mitochondrial tRNAAsn, tRNAGln, tRNAGlu and tRNAPro.
Jia Z, Meng F, Chen H, Zhu G, Li X, He Y, Zhang L, He X, Zhan H, Chen M, Ji Y, Wang M, Guan MX
Nucleic acids research 2022 Sep 9;50(16):9368-9381
Nucleic acids research 2022 Sep 9;50(16):9368-9381
N4-acetylcytidine regulates the replication and pathogenicity of enterovirus 71.
Hao H, Liu W, Miao Y, Ma L, Yu B, Liu L, Yang C, Zhang K, Chen Z, Yang J, Zheng Z, Zhang B, Deng F, Gong P, Yuan J, Hu Z, Guan W
Nucleic acids research 2022 Sep 9;50(16):9339-9354
Nucleic acids research 2022 Sep 9;50(16):9339-9354
Lactobacillus rhamnosus GR-1 attenuates foodborne Bacillus cereus-induced NLRP3 inflammasome activity in bovine mammary epithelial cells by protecting intercellular tight junctions.
Shan Q, Liu N, Wang X, Zhu Y, Yin J, Wang J
Journal of animal science and biotechnology 2022 Sep 9;13(1):101
Journal of animal science and biotechnology 2022 Sep 9;13(1):101
Lactobacillusjohnsonii L531 Protects against Salmonella Infantis-Induced Intestinal Damage by Regulating the NOD Activation, Endoplasmic Reticulum Stress, and Autophagy.
Yang L, Wang JF, Liu N, Wang X, Wang J, Yang GH, Yang GY, Zhu YH
International journal of molecular sciences 2022 Sep 8;23(18)
International journal of molecular sciences 2022 Sep 8;23(18)
THZ1 targeting CDK7 suppresses c-KIT transcriptional activity in gastrointestinal stromal tumours.
Sun J, Zhang Q, Sun X, Xue A, Gao X, Shen K
Cell communication and signaling : CCS 2022 Sep 8;20(1):138
Cell communication and signaling : CCS 2022 Sep 8;20(1):138
Targeting Therapeutic Resistance and Multinucleate Giant Cells in CCNE1-Amplified HR-Proficient Ovarian Cancer.
Bai S, Taylor SE, Jamalruddin MA, McGonigal S, Grimley E, Yang D, Bernstein KA, Buckanovich RJ
Molecular cancer therapeutics 2022 Sep 6;21(9):1473-1484
Molecular cancer therapeutics 2022 Sep 6;21(9):1473-1484
Mitochondrial outer membrane protein FUNDC2 promotes ferroptosis and contributes to doxorubicin-induced cardiomyopathy.
Ta N, Qu C, Wu H, Zhang D, Sun T, Li Y, Wang J, Wang X, Tang T, Chen Q, Liu L
Proceedings of the National Academy of Sciences of the United States of America 2022 Sep 6;119(36):e2117396119
Proceedings of the National Academy of Sciences of the United States of America 2022 Sep 6;119(36):e2117396119
CPEB2 m6A methylation regulates blood-tumor barrier permeability by regulating splicing factor SRSF5 stability.
Zhang M, Yang C, Ruan X, Liu X, Wang D, Liu L, Shao L, Wang P, Dong W, Xue Y
Communications biology 2022 Sep 5;5(1):908
Communications biology 2022 Sep 5;5(1):908
Pou3f1 mediates the effect of Nfatc3 on ulcerative colitis-associated colorectal cancer by regulating inflammation.
Lin Y, Wang D, Zhao H, Li D, Li X, Lin L
Cellular & molecular biology letters 2022 Sep 5;27(1):75
Cellular & molecular biology letters 2022 Sep 5;27(1):75
LINC00839 promotes colorectal cancer progression by recruiting RUVBL1/Tip60 complexes to activate NRF1.
Liu X, Chen J, Zhang S, Liu X, Long X, Lan J, Zhou M, Zheng L, Zhou J
EMBO reports 2022 Sep 5;23(9):e54128
EMBO reports 2022 Sep 5;23(9):e54128
Lysosomal K(+) channel TMEM175 promotes apoptosis and aggravates symptoms of Parkinson's disease.
Qu L, Lin B, Zeng W, Fan C, Wu H, Ge Y, Li Q, Li C, Wei Y, Xin J, Wang X, Liu D, Cang C
EMBO reports 2022 Sep 5;23(9):e53234
EMBO reports 2022 Sep 5;23(9):e53234
Knockdown of FOXA1 enhances the osteogenic differentiation of human bone marrow mesenchymal stem cells partly via activation of the ERK1/2 signalling pathway.
Li L, Wang Y, Wang Z, Xue D, Dai C, Gao X, Ma J, Hang K, Pan Z
Stem cell research & therapy 2022 Sep 5;13(1):456
Stem cell research & therapy 2022 Sep 5;13(1):456
Hsa_circ_0001485 promoted osteogenic differentiation by targeting BMPR2 to activate the TGFβ-BMP pathway.
Chen SC, Jiang T, Liu QY, Liu ZT, Su YF, Su HT
Stem cell research & therapy 2022 Sep 5;13(1):453
Stem cell research & therapy 2022 Sep 5;13(1):453
Prinsepiae Nux Extract Activates NRF2 Activity and Protects UVB-Induced Damage in Keratinocyte.
Wang SH, Chen YS, Lai KH, Lu CK, Chang HS, Wu HC, Yen FL, Chen LY, Lee JC, Yen CH
Antioxidants (Basel, Switzerland) 2022 Sep 5;11(9)
Antioxidants (Basel, Switzerland) 2022 Sep 5;11(9)
miR-124 regulates early isolation-induced social abnormalities via inhibiting myelinogenesis in the medial prefrontal cortex.
Zhang Y, Pang Y, Feng W, Jin Y, Chen S, Ding S, Wang Z, Zou Y, Li Y, Wang T, Sun P, Gao J, Zhu Y, Ke X, Marshall C, Huang H, Sheng C, Xiao M
Cellular and molecular life sciences : CMLS 2022 Sep 4;79(9):507
Cellular and molecular life sciences : CMLS 2022 Sep 4;79(9):507
Low Expression of Mitofusin 1 Gene Leads to Mitochondrial Dysfunction and Embryonic Genome Activation Failure in Ovine-Bovine Inter-Species Cloned Embryos.
Wu S, Zhao X, Wu M, Yang L, Liu X, Li D, Xu H, Zhao Y, Su X, Wei Z, Bai C, Su G, Li G
International journal of molecular sciences 2022 Sep 4;23(17)
International journal of molecular sciences 2022 Sep 4;23(17)
Oxalate induces the ossification of RTECs by activating the JAK2/STAT3 signaling pathway and participates in the formation of kidney stones.
Song Q, Liao W, He Z, Li D, Dong C, Song C, Yang S
Archives of biochemistry and biophysics 2022 Sep 30;727:109325
Archives of biochemistry and biophysics 2022 Sep 30;727:109325
Palmitic acid promotes endothelial-to-mesenchymal transition via activation of the cytosolic DNA-sensing cGAS-STING pathway.
Liu Q, Cheng Z, Huang B, Luo S, Guo Y
Archives of biochemistry and biophysics 2022 Sep 30;727:109321
Archives of biochemistry and biophysics 2022 Sep 30;727:109321
Supramolecular Hydrogel-Wrapped Gingival Mesenchymal Stem Cells in Cutaneous Radiation Injury.
Nie S, Ren C, Liang X, Cai H, Sun H, Liu F, Ji K, Wang Y, Liu Q
Cells 2022 Sep 30;11(19)
Cells 2022 Sep 30;11(19)
WTAP promotes oesophageal squamous cell carcinoma development by decreasing CPSF4 expression in an m(6)A-dependent manner.
Luo Q, Zhan X, Kuang Y, Sun M, Dong F, Sun E, Chen B
Medical oncology (Northwood, London, England) 2022 Sep 29;39(12):231
Medical oncology (Northwood, London, England) 2022 Sep 29;39(12):231
Moxidectin induces autophagy arrest in colorectal cancer.
Mao Y, Xie H, Shu D, Cheng L, Lan J, Pan K
Medical oncology (Northwood, London, England) 2022 Sep 29;39(12):211
Medical oncology (Northwood, London, England) 2022 Sep 29;39(12):211
The AHNAK induces increased IL-6 production in CD4+ T cells and serves as a potential diagnostic biomarker for recurrent pregnancy loss.
Li L, Liu Y, Feng T, Zhou W, Wang Y, Li H
Clinical and experimental immunology 2022 Sep 29;209(3):291-304
Clinical and experimental immunology 2022 Sep 29;209(3):291-304
Thyroid Hormone Induces Oral Cancer Growth via the PD-L1-Dependent Signaling Pathway.
Su KW, Lin HY, Chiu HC, Shen SY, ChangOu CA, Crawford DR, Yang YSH, Shih YJ, Li ZL, Huang HM, Whang-Peng J, Ho Y, Wang K
Cells 2022 Sep 29;11(19)
Cells 2022 Sep 29;11(19)
HIV-1 Preintegration Complex Preferentially Integrates the Viral DNA into Nucleosomes Containing Trimethylated Histone 3-Lysine 36 Modification and Flanking Linker DNA.
Sapp N, Burge N, Cox K, Prakash P, Balasubramaniam M, Thapa S, Christensen D, Li M, Linderberger J, Kvaratskhelia M, Pandhare J, Craigie R, Poirier MG, Dash C
Journal of virology 2022 Sep 28;96(18):e0101122
Journal of virology 2022 Sep 28;96(18):e0101122
ACLP promotes activation of cancer-associated fibroblasts and tumor metastasis via ACLP-PPARγ-ACLP feedback loop in pancreatic cancer.
Li YX, Zhu XX, Wu X, Li JH, Ni XH, Li SJ, Zhao W, Yin XY
Cancer letters 2022 Sep 28;544:215802
Cancer letters 2022 Sep 28;544:215802
METTL3 suppresses anlotinib sensitivity by regulating m(6)A modification of FGFR3 in oral squamous cell carcinoma.
Chen J, Li S, Huang Z, Cao C, Wang A, He Q
Cancer cell international 2022 Sep 27;22(1):295
Cancer cell international 2022 Sep 27;22(1):295
ABAT gene expression associated with the sensitivity of hypomethylating agents in myelodysplastic syndrome through CXCR4/mTOR signaling.
Zhao G, Li S, Wang Q, Wu W, Fu X, Zhu C, Wang W, Wang X
Cell death discovery 2022 Sep 26;8(1):398
Cell death discovery 2022 Sep 26;8(1):398
Dexmedetomidine prevents hemorrhagic brain injury by reducing damage induced by ferroptosis in mice.
Liu MJ, Zhao XC, Gong HS, You YQ, Li JY
Neuroscience letters 2022 Sep 25;788:136842
Neuroscience letters 2022 Sep 25;788:136842
Expression profiles of microRNAs in midbrain of MPTP-treated mice determined by microRNA sequencing.
Liu X, Qi Y, Zhao G, Zhang Z, Cao Y, Li Y, Xue J, Tang X
Neuroscience letters 2022 Sep 25;788:136841
Neuroscience letters 2022 Sep 25;788:136841
β-Klotho Promotes the Development of Intrauterine Adhesions via the PI3K/AKT Signaling Pathway.
Guo Z, Wang Y, Wen X, Xu X, Yan L
International journal of molecular sciences 2022 Sep 25;23(19)
International journal of molecular sciences 2022 Sep 25;23(19)
2-Deoxy-D-glucose Alleviates Cancer Cachexia-Induced Muscle Wasting by Enhancing Ketone Metabolism and Inhibiting the Cori Cycle.
Wei L, Wang R, Wazir J, Lin K, Song S, Li L, Pu W, Zhao C, Wang Y, Su Z, Wang H
Cells 2022 Sep 25;11(19)
Cells 2022 Sep 25;11(19)
Antiviral Drugs Screening for Swine Acute Diarrhea Syndrome Coronavirus.
Chen Y, You Y, Wang S, Jiang L, Tian L, Zhu S, An X, Song L, Tong Y, Fan H
International journal of molecular sciences 2022 Sep 24;23(19)
International journal of molecular sciences 2022 Sep 24;23(19)
Exosomal AP000439.2 from clear cell renal cell carcinoma induces M2 macrophage polarization to promote tumor progression through activation of STAT3.
Shen T, Miao S, Zhou Y, Yi X, Xue S, Du B, Tang C, Qu L, Fu D, Jia R, He H
Cell communication and signaling : CCS 2022 Sep 24;20(1):152
Cell communication and signaling : CCS 2022 Sep 24;20(1):152
PKM2 promotes pulmonary fibrosis by stabilizing TGF-β1 receptor I and enhancing TGF-β1 signaling.
Gao S, Li X, Jiang Q, Liang Q, Zhang F, Li S, Zhang R, Luan J, Zhu J, Gu X, Xiao T, Huang H, Chen S, Ning W, Yang G, Yang C, Zhou H
Science advances 2022 Sep 23;8(38):eabo0987
Science advances 2022 Sep 23;8(38):eabo0987
IDH1 Promotes Foam Cell Formation by Aggravating Macrophage Ferroptosis.
Li B, Wang C, Lu P, Ji Y, Wang X, Liu C, Lu X, Xu X, Wang X
Biology 2022 Sep 23;11(10)
Biology 2022 Sep 23;11(10)
Statin shapes inflamed tumor microenvironment and enhances immune checkpoint blockade in non-small cell lung cancer.
Mao W, Cai Y, Chen D, Jiang G, Xu Y, Chen R, Wang F, Wang X, Zheng M, Zhao X, Mei J
JCI insight 2022 Sep 22;7(18)
JCI insight 2022 Sep 22;7(18)
FTH1- and SAT1-Induced Astrocytic Ferroptosis Is Involved in Alzheimer's Disease: Evidence from Single-Cell Transcriptomic Analysis.
Dang Y, He Q, Yang S, Sun H, Liu Y, Li W, Tang Y, Zheng Y, Wu T
Pharmaceuticals (Basel, Switzerland) 2022 Sep 22;15(10)
Pharmaceuticals (Basel, Switzerland) 2022 Sep 22;15(10)
Activation of oxytocin receptors in mouse GABAergic amacrine cells modulates retinal dopaminergic signaling.
Hu S, Wang Y, Han X, Dai M, Zhang Y, Ma Y, Weng S, Xiao L
BMC biology 2022 Sep 21;20(1):205
BMC biology 2022 Sep 21;20(1):205
Elevated ganglioside GM2 activator (GM2A) in human brain tissue reduces neurite integrity and spontaneous neuronal activity.
Hsieh YC, Negri J, He A, Pearse RV 2nd, Liu L, Duong DM, Chibnik LB, Bennett DA, Seyfried NT, Young-Pearse TL
Molecular neurodegeneration 2022 Sep 21;17(1):61
Molecular neurodegeneration 2022 Sep 21;17(1):61
Silencing circFTO inhibits malignant phenotype through modulating DUSP4 expression in clear cell renal cell carcinoma.
Yang C, Zang Y, Wu S, Zhou Q, Ou Y, Ding Q, Wang H, Xiong Z
Cell death discovery 2022 Sep 20;8(1):392
Cell death discovery 2022 Sep 20;8(1):392
A new K(+)channel-independent mechanism is involved in the antioxidant effect of XE-991 in an in vitro model of glucose metabolism impairment: implications for Alzheimer's disease.
Piccirillo S, Preziuso A, Amoroso S, Serfilippi T, Miceli F, Magi S, Lariccia V
Cell death discovery 2022 Sep 20;8(1):391
Cell death discovery 2022 Sep 20;8(1):391
The Novel Protein ADAMTS16 Promotes Gastric Carcinogenesis by Targeting IFI27 through the NF-κb Signaling Pathway.
Li T, Zhou J, Jiang Y, Zhao Y, Huang J, Li W, Huang Z, Chen Z, Tang X, Chen H, Yang Z
International journal of molecular sciences 2022 Sep 20;23(19)
International journal of molecular sciences 2022 Sep 20;23(19)
Hnrnpk maintains chondrocytes survival and function during growth plate development via regulating Hif1α-glycolysis axis.
Chen Y, Wu J, Zhang S, Gao W, Liao Z, Zhou T, Li Y, Su D, Liu H, Yang X, Su P, Xu C
Cell death & disease 2022 Sep 20;13(9):803
Cell death & disease 2022 Sep 20;13(9):803
MED16 Promotes Tumour Progression and Tamoxifen Sensitivity by Modulating Autophagy through the mTOR Signalling Pathway in ER-Positive Breast Cancer.
Li H, Li K, Shu D, Shen M, Tan Z, Zhang W, Pu D, Tan W, Tang Z, Jin A, Liu S
Life (Basel, Switzerland) 2022 Sep 20;12(10)
Life (Basel, Switzerland) 2022 Sep 20;12(10)
Tissue-restricted inhibition of mTOR using chemical genetics.
Wassarman DR, Bankapalli K, Pallanck LJ, Shokat KM
Proceedings of the National Academy of Sciences of the United States of America 2022 Sep 20;119(38):e2204083119
Proceedings of the National Academy of Sciences of the United States of America 2022 Sep 20;119(38):e2204083119
Strategies for understanding the role of cellular heterogeneity in the pathogenesis of lung cancer: a cell model for chronic exposure to cigarette smoke extract.
Xia D, Liu J, Yong J, Li X, Ji W, Zhao Z, Wang X, Xiao C, Wu S, Liu H, Zhao H, He Y
BMC pulmonary medicine 2022 Sep 2;22(1):333
BMC pulmonary medicine 2022 Sep 2;22(1):333
Proteomics and Biochemical Analyses of Secreted Proteins Revealed a Novel Mechanism by Which ADAM12S Regulates the Migration of Gastric Cancer Cells.
Chang Z, Duan Q, Yu C, Li D, Jiang H, Ge F, Xu G
Journal of proteome research 2022 Sep 2;21(9):2160-2172
Journal of proteome research 2022 Sep 2;21(9):2160-2172
Micropeptide MIAC inhibits the tumor progression by interacting with AQP2 and inhibiting EREG/EGFR signaling in renal cell carcinoma.
Li M, Liu G, Jin X, Guo H, Setrerrahmane S, Xu X, Li T, Lin Y, Xu H
Molecular cancer 2022 Sep 19;21(1):181
Molecular cancer 2022 Sep 19;21(1):181
Cell adhesion molecule BVES functions as a suppressor of tumor cells extrusion in hepatocellular carcinoma metastasis.
Han P, Lei Y, Liu J, Liu J, Huang H, Tian D, Yan W
Cell communication and signaling : CCS 2022 Sep 19;20(1):149
Cell communication and signaling : CCS 2022 Sep 19;20(1):149
TWIST1 induces proteasomal degradation of β-catenin during the differentiation of ovarian cancer stem-like cells.
Liu J, Shu G, Wu A, Zhang X, Zhou Z, Alvero AB, Mor G, Yin G
Scientific reports 2022 Sep 19;12(1):15650
Scientific reports 2022 Sep 19;12(1):15650
Biomimetic Red Blood Cell Membrane-Mediated Nanodrugs Loading Ursolic Acid for Targeting NSCLC Therapy.
Wu T, Yan D, Hou W, Jiang H, Wu M, Wang Y, Chen G, Tang C, Wang Y, Xu H
Cancers 2022 Sep 18;14(18)
Cancers 2022 Sep 18;14(18)
CAV2 promotes the invasion and metastasis of head and neck squamous cell carcinomas by regulating S100 proteins.
Wang Y, Wang Y, Liu R, Wang C, Luo Y, Chen L, He Y, Zhu K, Guo H, Zhang Z, Luo J
Cell death discovery 2022 Sep 16;8(1):386
Cell death discovery 2022 Sep 16;8(1):386
CTCF DNA-binding domain undergoes dynamic and selective protein-protein interactions.
Zhou R, Tian K, Huang J, Duan W, Fu H, Feng Y, Wang H, Jiang Y, Li Y, Wang R, Hu J, Ma H, Qi Z, Ji X
iScience 2022 Sep 16;25(9):105011
iScience 2022 Sep 16;25(9):105011
Confined migration induces heterochromatin formation and alters chromatin accessibility.
Hsia CR, McAllister J, Hasan O, Judd J, Lee S, Agrawal R, Chang CY, Soloway P, Lammerding J
iScience 2022 Sep 16;25(9):104978
iScience 2022 Sep 16;25(9):104978
TMUB1 is an endoplasmic reticulum-resident escortase that promotes the p97-mediated extraction of membrane proteins for degradation.
Wang L, Li J, Wang Q, Ge MX, Ji J, Liu D, Wang Z, Cao Y, Zhang Y, Zhang ZR
Molecular cell 2022 Sep 15;82(18):3453-3467.e14
Molecular cell 2022 Sep 15;82(18):3453-3467.e14
An integrated study of Shenling Baizhu San against hyperuricemia: Efficacy evaluation, core target identification and active component discovery.
Wang Y, Lin ZJ, Huang J, Chu MZ, Ding XL, Li WJ, Mao QY, Zhang B
Journal of ethnopharmacology 2022 Sep 15;295:115450
Journal of ethnopharmacology 2022 Sep 15;295:115450
Th17/Treg imbalance mediates hepatic intolerance to exogenous lipopolysaccharide and exacerbates liver injury in triptolide induced excessive immune response.
Zhang H, Yuan Z, Zhu Y, Yuan Z, Wang J, Nong C, Zhou S, Tang Q, Zhang L, Jiang Z, Yu Q
Journal of ethnopharmacology 2022 Sep 15;295:115422
Journal of ethnopharmacology 2022 Sep 15;295:115422
Yangjing Zhongyu decoction facilitates mitochondrial activity, estrogenesis, and energy metabolism in H(2)O(2)-induced human granulosa cell line KGN.
Liu J, Shi D, Ma Q, Zhao P
Journal of ethnopharmacology 2022 Sep 15;295:115398
Journal of ethnopharmacology 2022 Sep 15;295:115398
Aberrant human ClpP activation disturbs mitochondrial proteome homeostasis to suppress pancreatic ductal adenocarcinoma.
Wang P, Zhang T, Wang X, Xiao H, Li H, Zhou LL, Yang T, Wei B, Zhu Z, Zhou L, Yang S, Lu X, Zhang Y, Huang Y, Gan J, Yang CG
Cell chemical biology 2022 Sep 15;29(9):1396-1408.e8
Cell chemical biology 2022 Sep 15;29(9):1396-1408.e8
Blockage of the IDO1 pathway by charge-switchable nanoparticles amplifies immunogenic cell death for enhanced cancer immunotherapy.
Shi M, Zhang J, Wang Y, Han Y, Zhao X, Hu H, Qiao M, Chen D
Acta biomaterialia 2022 Sep 15;150:353-366
Acta biomaterialia 2022 Sep 15;150:353-366
Small-molecule eRF3a degraders rescue CFTR nonsense mutations by promoting premature termination codon readthrough.
Lee RE, Lewis CA, He L, Bulik-Sullivan EC, Gallant SC, Mascenik TM, Dang H, Cholon DM, Gentzsch M, Morton LC, Minges JT, Theile JW, Castle NA, Knowles MR, Kimple AJ, Randell SH
The Journal of clinical investigation 2022 Sep 15;132(18)
The Journal of clinical investigation 2022 Sep 15;132(18)
Blockage of Orai1-Nucleolin interaction meditated calcium influx attenuates breast cancer cells growth.
Gu C, Zhang W, Yang E, Gu C, Zhang Z, Ke J, Wang X, Wu S, Li S, Wu F
Oncogenesis 2022 Sep 15;11(1):55
Oncogenesis 2022 Sep 15;11(1):55
Adaptive Mutation in the Main Protease Cleavage Site of Feline Coronavirus Renders the Virus More Resistant to Main Protease Inhibitors.
Jiao Z, Yan Y, Chen Y, Wang G, Wang X, Li L, Yang M, Hu X, Guo Y, Shi Y, Peng G
Journal of virology 2022 Sep 14;96(17):e0090722
Journal of virology 2022 Sep 14;96(17):e0090722
Differential Protective Effect of Resveratrol and Its Microbial Metabolites on Intestinal Barrier Dysfunction is Mediated by the AMPK Pathway.
Zhang B, Zhang Y, Liu X, Yin J, Li X, Zhang X, Xing X, Wang J, Wang S
Journal of agricultural and food chemistry 2022 Sep 14;70(36):11301-11313
Journal of agricultural and food chemistry 2022 Sep 14;70(36):11301-11313
The interaction between autophagy and the epithelial-mesenchymal transition mediated by NICD/ULK1 is involved in the formation of diabetic cataracts.
Ma J, Ye W, Yang Y, Wu T, Wang Y, Li J, Pei R, He M, Zhang L, Zhou J
Molecular medicine (Cambridge, Mass.) 2022 Sep 14;28(1):116
Molecular medicine (Cambridge, Mass.) 2022 Sep 14;28(1):116
Upregulation of miR-520c-3p via hepatitis B virus drives hepatocellular migration and invasion by the PTEN/AKT/NF-κB axis.
Liu Y, Wang J, Chen J, Wu S, Zeng X, Xiong Q, Guo Y, Sun J, Song F, Xu J, Yuan S, Li C, He Y, Wang M, Chen L, Shi YB, Guo M, Guo D, Sun G
Molecular therapy. Nucleic acids 2022 Sep 13;29:47-63
Molecular therapy. Nucleic acids 2022 Sep 13;29:47-63
A covalent inhibitor of K-Ras(G12C) induces MHC class I presentation of haptenated peptide neoepitopes targetable by immunotherapy.
Zhang Z, Rohweder PJ, Ongpipattanakul C, Basu K, Bohn MF, Dugan EJ, Steri V, Hann B, Shokat KM, Craik CS
Cancer cell 2022 Sep 12;40(9):1060-1069.e7
Cancer cell 2022 Sep 12;40(9):1060-1069.e7
GCAF(TMEM251) regulates lysosome biogenesis by activating the mannose-6-phosphate pathway.
Zhang W, Yang X, Li Y, Yu L, Zhang B, Zhang J, Cho WJ, Venkatarangan V, Chen L, Burugula BB, Bui S, Wang Y, Duan C, Kitzman JO, Li M
Nature communications 2022 Sep 12;13(1):5351
Nature communications 2022 Sep 12;13(1):5351
Hypoxia-induced polarization of M2 macrophages and C-C motif chemokine ligand 5 secretion promotes the migration and invasion of trophoblasts†.
Chen X, Song QL, Ji R, Wang JY, Li ZH, Xiao ZN, Guo DY, Yang J
Biology of reproduction 2022 Sep 12;107(3):834-845
Biology of reproduction 2022 Sep 12;107(3):834-845
A novel homozygous mutation in the PADI6 gene causes early embryo arrest.
Wang X, Zhu H, He Y, Zeng J, Zhao J, Xia Q, Wu L, Yao Z, Li Y
Reproductive health 2022 Sep 10;19(1):190
Reproductive health 2022 Sep 10;19(1):190
Transient Receptor Potential Vanilloid Type 1 Protects Against Pressure Overload-Induced Cardiac Hypertrophy by Promoting Mitochondria-Associated Endoplasmic Reticulum Membranes.
Wang Y, Li X, Xu X, Qu X, Yang Y
Journal of cardiovascular pharmacology 2022 Sep 1;80(3):430-441
Journal of cardiovascular pharmacology 2022 Sep 1;80(3):430-441
BCAP31 is involved in modulating colorectal cancer cell proliferation via the Emerin/β-catenin axis.
Han L, Shi J, Zhao L, Deng J, Li Y, Zhao H, Wang H, Yan Y, Zou F
Experimental cell research 2022 Sep 1;418(1):113265
Experimental cell research 2022 Sep 1;418(1):113265
A20 inhibits periodontal bone resorption and NLRP3-mediated M1 macrophage polarization.
Hou L, Ye Y, Gou H, Tang H, Zhou Y, Xu X, Xu Y
Experimental cell research 2022 Sep 1;418(1):113264
Experimental cell research 2022 Sep 1;418(1):113264
MCTR1 inhibits ferroptosis by promoting NRF2 expression to attenuate hepatic ischemia-reperfusion injury.
Ye J, Peng J, Liu K, Zhang T, Huang W
American journal of physiology. Gastrointestinal and liver physiology 2022 Sep 1;323(3):G283-G293
American journal of physiology. Gastrointestinal and liver physiology 2022 Sep 1;323(3):G283-G293
Interaction between VPS13A and the XK scramblase is important for VPS13A function in humans.
Park JS, Hu Y, Hollingsworth NM, Miltenberger-Miltenyi G, Neiman AM
Journal of cell science 2022 Sep 1;135(17)
Journal of cell science 2022 Sep 1;135(17)
Functional Phosphoproteomics in Cancer Chemoresistance Using CRISPR-Mediated Base Editors.
Li J, Lin J, Huang S, Li M, Yu W, Zhao Y, Guo J, Zhang P, Huang X, Qiao Y
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2022 Oct;9(30):e2200717
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2022 Oct;9(30):e2200717
Generation of a homozygous P4HA2 knockout human embryonic stem cell line (FDCHDPe012-A) by CRISPR/Cas9 system.
You J, Ma S, Zhang H, Chen L
Stem cell research 2022 Oct;64:102930
Stem cell research 2022 Oct;64:102930
Activation of DDX58/RIG‑I suppresses the growth of tumor cells by inhibiting STAT3/CSE signaling in colon cancer.
Deng Y, Fu H, Han X, Li Y, Zhao W, Zhao X, Yu C, Guo W, Lei K, Wang T
International journal of oncology 2022 Oct;61(4)
International journal of oncology 2022 Oct;61(4)
LIS1 interacts with CLIP170 to promote tumor growth and metastasis via the Cdc42 signaling pathway in salivary gland adenoid cystic carcinoma.
Li L, Wen Z, Kou N, Liu J, Jin D, Wang L, Wang F, Gao L
International journal of oncology 2022 Oct;61(4)
International journal of oncology 2022 Oct;61(4)
GDNF Promotes Astrocyte Abnormal Proliferation and Migration Through the GFRα1/RET/MAPK/pCREB/LOXL2 Signaling Axis.
Wang M, Han X, Zha W, Wang X, Liu L, Li Z, Shi Y, Kan X, Wang G, Gao D, Zhang B
Molecular neurobiology 2022 Oct;59(10):6321-6340
Molecular neurobiology 2022 Oct;59(10):6321-6340
TRIM47 promotes glioma angiogenesis by suppressing Smad4.
Wang Z, Li Z, Han C, Cheng Y, Wang K
In vitro cellular & developmental biology. Animal 2022 Oct;58(9):771-779
In vitro cellular & developmental biology. Animal 2022 Oct;58(9):771-779
AKR1B10 accelerates the production of proinflammatory cytokines via the NF-κB signaling pathway in colon cancer.
Liu C, Shi L, Li W, Huang Z, Wang S, Xu P, Li T, Li Z, Luo F, Li W, Yan J, Wu T
Journal of molecular histology 2022 Oct;53(5):781-791
Journal of molecular histology 2022 Oct;53(5):781-791
Impact of ATP synthase/coupling factor 6 in hypoxic pulmonary arterial hypertension: An experimental rat model.
Lı N, Shı Y, Yın J, Sun L, Zhang Q, Bao S, Zhang J, Lı Y, Wang M, Zhang Y, Xue M, Qı L, Lı Y, Yan S, Lı X
Turkish journal of medical sciences 2022 Oct;52(5):1468-1477
Turkish journal of medical sciences 2022 Oct;52(5):1468-1477
Depletion of serum-derived exosomes aggravates heat stress-induced damage of bovine mammary epithelial cells.
Wang Y, Wang HL, Lin ZP, Zhong JF, Chen KL, Duan X
Molecular biology reports 2022 Oct;49(10):9297-9305
Molecular biology reports 2022 Oct;49(10):9297-9305
TMBIM6 promotes diabetic tubular epithelial cell survival and albumin endocytosis by inhibiting the endoplasmic reticulum stress sensor, IRE1α.
Xie H, Shi Y, Zhou Y, Liu H
Molecular biology reports 2022 Oct;49(10):9181-9194
Molecular biology reports 2022 Oct;49(10):9181-9194
HIF-1α inhibits T-2 toxin-mediated "immune evasion" process by negatively regulating PD-1/PD-L1.
You L, Wang X, Wu W, Nepovimova E, Wu Q, Kuca K
Toxicology 2022 Oct;480:153324
Toxicology 2022 Oct;480:153324
Promotion of angiogenesis in vitro by Astragalus polysaccharide via activation of TLR4 signaling pathway.
Qiu H, Zhang L, He X, Wei Y, Wang M, Ma B, Hu D, Shi Z
Journal of food biochemistry 2022 Oct;46(10):e14329
Journal of food biochemistry 2022 Oct;46(10):e14329
Proteasomal deubiquitylase activity enhances cell surface recycling of the epidermal growth factor receptor in non-small cell lung cancer.
Wang S, Wang T, Yang Q, Cheng S, Liu F, Yang G, Wang F, Wang R, Yang D, Zhou M, Duan C, Zhang Y, Liu H, Dai Z, Tian K, Liu S
Cellular oncology (Dordrecht, Netherlands) 2022 Oct;45(5):951-965
Cellular oncology (Dordrecht, Netherlands) 2022 Oct;45(5):951-965
Ulinastatin Alleviates Rhabdomyolysis-Induced Acute Kidney Injury by Suppressing Inflammation and Apoptosis via Inhibiting TLR4/NF-κB Signaling Pathway.
Wang J, Xu G, Jin H, Chai Y, Yang X, Liu Z, Hou S, Fan H
Inflammation 2022 Oct;45(5):2052-2065
Inflammation 2022 Oct;45(5):2052-2065
ADH1C inhibits progression of colorectal cancer through the ADH1C/PHGDH /PSAT1/serine metabolic pathway.
Li S, Yang H, Li W, Liu JY, Ren LW, Yang YH, Ge BB, Zhang YZ, Fu WQ, Zheng XJ, Du GH, Wang JH
Acta pharmacologica Sinica 2022 Oct;43(10):2709-2722
Acta pharmacologica Sinica 2022 Oct;43(10):2709-2722
CYP24A1 Involvement in Inflammatory Factor Regulation Occurs via the Wnt Signaling Pathway.
Chen XQ, Mao JY, Wang CS, Li WB, Han TT, Lv K, Li JN
Current medical science 2022 Oct;42(5):1022-1032
Current medical science 2022 Oct;42(5):1022-1032
Linear ubiquitination of PTEN impairs its function to promote prostate cancer progression.
Guo Y, He J, Zhang H, Chen R, Li L, Liu X, Huang C, Qiang Z, Zhou Z, Wang Y, Huang J, Zhao X, Zheng J, Chen GQ, Yu J
Oncogene 2022 Oct;41(44):4877-4892
Oncogene 2022 Oct;41(44):4877-4892
Cdo1 promotes PPARγ-mediated adipose tissue lipolysis in male mice.
Guo YY, Li BY, Xiao G, Liu Y, Guo L, Tang QQ
Nature metabolism 2022 Oct;4(10):1352-1368
Nature metabolism 2022 Oct;4(10):1352-1368
Pore-forming protein βγ-CAT promptly responses to fasting with capacity to deliver macromolecular nutrients.
Shi ZH, Zhao Z, Liu LZ, Bian XL, Zhang Y
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2022 Oct;36(10):e22533
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2022 Oct;36(10):e22533
Exosomes derived from mesenchymal stem cells attenuate diabetic kidney disease by inhibiting cell apoptosis and epithelial-to-mesenchymal transition via miR-424-5p.
Cui C, Zang N, Song J, Guo X, He Q, Hu H, Yang M, Wang Y, Yang J, Zou Y, Gao J, Wang L, Wang C, Liu F, He F, Hou X, Chen L
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2022 Oct;36(10):e22517
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2022 Oct;36(10):e22517
MicroRNA-124 attenuates PTSD-like behaviors and reduces the level of inflammatory cytokines by downregulating the expression of TRAF6 in the hippocampus of rats following single-prolonged stress.
Chen Y, An Q, Yang ST, Chen YL, Tong L, Ji LL
Experimental neurology 2022 Oct;356:114154
Experimental neurology 2022 Oct;356:114154
The phosphorylation and dephosphorylation switch of VCP/p97 regulates the architecture of centrosome and spindle.
Zhu K, Cai Y, Si X, Ye Z, Gao Y, Liu C, Wang R, Ma Z, Zhu H, Zhang L, Li S, Zhang H, Yue J
Cell death and differentiation 2022 Oct;29(10):2070-2088
Cell death and differentiation 2022 Oct;29(10):2070-2088
Upregulation of Wilms' Tumor 1 in epicardial cells increases cardiac fibrosis in dystrophic mice.
Guo Z, Geng M, Huang Y, Han G, Jing R, Lin C, Zhang X, Zhang M, Fan G, Wang F, Yin H
Cell death and differentiation 2022 Oct;29(10):1928-1940
Cell death and differentiation 2022 Oct;29(10):1928-1940
Eplerenone ameliorates lung fibrosis in unilateral ureteral obstruction rats by inhibiting lymphangiogenesis.
Liu Z, Zhang C, Hao J, Chen G, Liu L, Xiong Y, Chang Y, Li H, Shimosawa T, Yang F, Xu Q
Experimental and therapeutic medicine 2022 Oct;24(4):623
Experimental and therapeutic medicine 2022 Oct;24(4):623
TMEM14A aggravates the progression of human ovarian cancer cells by enhancing the activity of glycolysis.
Zhang Q, Wang X, Zhang X, Zhan J, Zhang B, Jia J, Chen J
Experimental and therapeutic medicine 2022 Oct;24(4):614
Experimental and therapeutic medicine 2022 Oct;24(4):614
FJX1 as a candidate diagnostic and prognostic serum biomarker for colorectal cancer.
Liu L, Huang Y, Li Y, Wang Q, Hao Y, Liu L, Yao X, Yao X, Wei Y, Sun X, Guo Y
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 2022 Oct;24(10):1964-1974
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 2022 Oct;24(10):1964-1974
KIAA1529 regulates RAD51 expression to confer PARP inhibitors resistance in ovarian cancer.
Qiao Y, Yu X, Zhou B, Zhang K, Huang J, Liao J
Translational oncology 2022 Oct;24:101497
Translational oncology 2022 Oct;24:101497
Effect of NMB-regulated ERK1/2 and p65 signaling pathway on proliferation and apoptosis of cervical cancer.
Zeng R, Xiong X
Pathology, research and practice 2022 Oct;238:154104
Pathology, research and practice 2022 Oct;238:154104
RNA-binding protein ELAVL4/HuD ameliorates Alzheimer's disease-related molecular changes in human iPSC-derived neurons.
van der Linden RJ, Gerritsen JS, Liao M, Widomska J, Pearse RV 2nd, White FM, Franke B, Young-Pearse TL, Poelmans G
Progress in neurobiology 2022 Oct;217:102316
Progress in neurobiology 2022 Oct;217:102316
Substance P promotes the progression of bronchial asthma through activating the PI3K/AKT/NF-κB pathway mediated cellular inflammation and pyroptotic cell death in bronchial epithelial cells.
Li M, Zhong X, Xu WT
Cell cycle (Georgetown, Tex.) 2022 Oct;21(20):2179-2191
Cell cycle (Georgetown, Tex.) 2022 Oct;21(20):2179-2191
Matrix metalloproteinase 3 restricts viral infection by enhancing host antiviral immunity.
Feng T, Tong H, Ming Z, Deng L, Liu J, Wu J, Chen Z, Yan Y, Dai J
Antiviral research 2022 Oct;206:105388
Antiviral research 2022 Oct;206:105388
MiR-582 Down-Regulates Lissencephaly-1 (LIS1) via P-Akt and MMP-2 to Inhibit Cholangiocarcinoma Cell Proliferation and Invasion.
Liu G, Li T, Ma L, Wang J, Yin Z
Iranian journal of biotechnology 2022 Oct;20(4):e3136
Iranian journal of biotechnology 2022 Oct;20(4):e3136
Skin chronological aging drives age-related bone loss via secretion of cystatin-A.
Liang W, Chen Q, Cheng S, Wei R, Li Y, Yao C, Ouyang Z, Kang D, Chen A, Liu Z, Li K, Bai X, Li Q, Huang B
Nature aging 2022 Oct;2(10):906-922
Nature aging 2022 Oct;2(10):906-922
Integrated Metabolomics and Network Pharmacology to Reveal the Mechanisms of Guizhi-Fuling Treatment for Myocardial Ischemia.
Duan B, Ye Y, Zhou Z, Han L, Huang F, Li J, Wang Q, Zeng X, Yu X
Chemistry & biodiversity 2022 Oct;19(10):e202200386
Chemistry & biodiversity 2022 Oct;19(10):e202200386
Induction of GLI1 by miR-27b-3p/FBXW7/KLF5 pathway contributes to pulmonary arterial hypertension.
Wang Q, Chai L, Zhang Q, Wang J, Liu J, Chen H, Wang Y, Chen Y, Shen N, Xie X, Li M
Journal of molecular and cellular cardiology 2022 Oct;171:16-29
Journal of molecular and cellular cardiology 2022 Oct;171:16-29
MicroRNA-28-5p as a potential diagnostic biomarker for chronic periodontitis and its role in cell proliferation and inflammatory response.
Huang P, Jia L
Journal of dental sciences 2022 Oct;17(4):1501-1509
Journal of dental sciences 2022 Oct;17(4):1501-1509
SARM1 participates in axonal degeneration and mitochondrial dysfunction in prion disease.
Lai MY, Li J, Zhang XX, Wu W, Li ZP, Sun ZX, Zhao MY, Yang DM, Wang DD, Li W, Zhao DM, Zhou XM, Yang LF
Neural regeneration research 2022 Oct;17(10):2293-2299
Neural regeneration research 2022 Oct;17(10):2293-2299
miR-126 downregulates CXCL12 expression in intestinal epithelial cells to suppress the recruitment and function of macrophages and tumorigenesis in a murine model of colitis-associated colorectal cancer.
Wu S, Yuan W, Luo W, Nie K, Wu X, Meng X, Shen Z, Wang X
Molecular oncology 2022 Oct;16(19):3465-3489
Molecular oncology 2022 Oct;16(19):3465-3489
Blockade of IL-6 inhibits tumor immune evasion and improves anti-PD-1 immunotherapy.
Li W, Wu Z, Meng W, Zhang C, Cheng M, Chen Y, Zou Y, Li K, Lin S, Xiong W, Wang Y, Lin Y, Ma W, Zhou W
Cytokine 2022 Oct;158:155976
Cytokine 2022 Oct;158:155976
Gegen Qinlian decoction ameliorates murine colitis by inhibiting the expansion of Enterobacteriaceae through activating PPAR-γ signaling.
Hu J, Tong Y, Shen Z, Li Y, Cheng C, Au R, Xu F, Liu Y, Zhu L, Shen H
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Oct;154:113571
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Oct;154:113571
Matrix metalloproteinase-7 promotes chronic kidney disease progression via the induction of inflammasomes and the suppression of autophagy.
Zheng CM, Lu KC, Chen YJ, Li CY, Lee YH, Chiu HW
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Oct;154:113565
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Oct;154:113565
Gentianella acuta improves TAC-induced cardiac remodelling by regulating the Notch and PI3K/Akt/FOXO1/3 pathways.
Zhou WW, Dai C, Liu WZ, Zhang C, Zhang Y, Yang GS, Guo QH, Li S, Yang HX, Li AY
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Oct;154:113564
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Oct;154:113564
Mechanical stretch aggravates vascular smooth muscle cell apoptosis and vascular remodeling by downregulating EZH2.
Zhong HY, Yuan C, Liu XL, Wang QQ, Li X, Zhao YC, Li X, Liu DD, Zheng TF, Zhang M
The international journal of biochemistry & cell biology 2022 Oct;151:106278
The international journal of biochemistry & cell biology 2022 Oct;151:106278
The mechanism underlying the TC-G 1008 rescue of reactive oxygen species (ROS)-induced osteoblast apoptosis by the upregulation of peroxiredoxin 1.
Yang P, Feng Q, Meng L, Tang R, Jiang Y, Liu H, Si H, Li M
The international journal of biochemistry & cell biology 2022 Oct;151:106276
The international journal of biochemistry & cell biology 2022 Oct;151:106276
Lithocarpus polystachyus (Sweet Tea) water extract promotes human hepatocytes HL7702 proliferation through activation of HGF/AKT/ERK signaling pathway.
Lei M, Chen N, Xu Y, Gong Q, Gao J
Chinese herbal medicines 2022 Oct;14(4):576-582
Chinese herbal medicines 2022 Oct;14(4):576-582
Evaluation of Neurotoxicity in BALB/c Mice following Chronic Exposure to Polystyrene Microplastics.
Jin H, Yang C, Jiang C, Li L, Pan M, Li D, Han X, Ding J
Environmental health perspectives 2022 Oct;130(10):107002
Environmental health perspectives 2022 Oct;130(10):107002
LHX2 facilitates the progression of nasopharyngeal carcinoma via activation of the FGF1/FGFR axis.
Xie T, Du K, Liu W, Liu C, Wang B, Tian Y, Li R, Huang X, Lin J, Jian H, Zhang J, Yuan Y
British journal of cancer 2022 Oct;127(7):1239-1253
British journal of cancer 2022 Oct;127(7):1239-1253
Cucurbitacin B-induced G2/M cell cycle arrest of conjunctival melanoma cells mediated by GRP78-FOXM1-KIF20A pathway.
Wei J, Chen X, Li Y, Li R, Bao K, Liao L, Xie Y, Yang T, Zhu J, Mao F, Ni S, Jia R, Xu X, Li J
Acta pharmaceutica Sinica. B 2022 Oct;12(10):3861-3876
Acta pharmaceutica Sinica. B 2022 Oct;12(10):3861-3876
Eupalinolide B attenuates lipopolysaccharide-induced acute lung injury through inhibition of NF-κB and MAPKs signaling by targeting TAK1 protein.
Yang L, Chen H, Hu Q, Liu L, Yuan Y, Zhang C, Tang J, Shen X
International immunopharmacology 2022 Oct;111:109148
International immunopharmacology 2022 Oct;111:109148
Mycoplasma gallisepticum induced exosomal gga-miR-193a to disturb cell proliferation, apoptosis, and cytokine production by targeting the KRAS/ERK signaling pathway.
Zou M, Fu Y, Zhao Y, Sun Y, Yin X, Peng X
International immunopharmacology 2022 Oct;111:109090
International immunopharmacology 2022 Oct;111:109090
Secoisolariciresinol diglucoside-derived metabolite, enterolactone, attenuates atopic dermatitis by suppressing Th2 immune response.
Yu L, Xu Q, Wang P, Luo J, Zheng Z, Zhou J, Zhang L, Sun L, Zuo D
International immunopharmacology 2022 Oct;111:109039
International immunopharmacology 2022 Oct;111:109039
The exon 12-containing LHX6 isoforms promote cervical cancer cell proliferation by regulating the MAPK signaling pathway.
Wang L, Zhou Y, Cao C, Lin S, Zhi W, Zhang D, Li J, Wei R, Jiang G, Xu H, Wang X, Xi L, Wu P
Cancer medicine 2022 Oct;11(19):3657-3673
Cancer medicine 2022 Oct;11(19):3657-3673
The prognostic value and mechanisms of centromere protein M in patients with lung adenocarcinoma.
Qi N, Niu Y, Li Z, Xiao L, Tang D, Gao W
Translational cancer research 2022 Oct;11(10):3471-3490
Translational cancer research 2022 Oct;11(10):3471-3490
The application of proteomics and metabolomics to reveal the molecular mechanism of Nutmeg-5 in ameliorating cardiac fibrosis following myocardial infarction.
Yan T, Zhu X, Zhang X, Jia X, Liu J, Wang X, Xiao Y, Xiao Z, Liu T, Dong Y
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Oct;105:154382
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Oct;105:154382
Demethylzeylasteral attenuates hepatic stellate cell activation and liver fibrosis by inhibiting AGAP2 mediated signaling.
Chen K, Guo W, Li R, Han Y, Gao Q, Wang S
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Oct;105:154349
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Oct;105:154349
Deletion of Smurf1 attenuates liver steatosis via stabilization of p53.
Lin W, Zhang X, Zhang C, Li L, Zhang J, Xie P, Zhan Y, An W
Laboratory investigation; a journal of technical methods and pathology 2022 Oct;102(10):1075-1087
Laboratory investigation; a journal of technical methods and pathology 2022 Oct;102(10):1075-1087
Effects of high-dose folic acid on protein metabolism in breast muscle and performance of broilers.
Liang S, Liu X, Zhao J, Liu R, Huang X, Liu Y, Yang X, Yang X
Poultry science 2022 Oct;101(10):101935
Poultry science 2022 Oct;101(10):101935
Platelet-rich plasma promotes diabetic ulcer repair through inhibition of ferroptosis.
Chen L, Wu D, Zhou L, Ye Y
Annals of translational medicine 2022 Oct;10(20):1121
Annals of translational medicine 2022 Oct;10(20):1121
Role of ROR2 in promoting gastric cancer metastasis by enhancing c-JUN-mediated MMP3 transcription.
Ge X, Lin F, Wu Z, Lin Y, Tang W, McKay MJ, Sahu A, Lino-Silva LS, Tseng J, Li J
Annals of translational medicine 2022 Oct;10(20):1117
Annals of translational medicine 2022 Oct;10(20):1117
CXCL12/CXCR7/β-arrestin1 biased signal promotes epithelial-to-mesenchymal transition of colorectal cancer by repressing miRNAs through YAP1 nuclear translocation.
Si M, Song Y, Wang X, Wang D, Liu X, Qu X, Song Z, Yu X
Cell & bioscience 2022 Oct 9;12(1):171
Cell & bioscience 2022 Oct 9;12(1):171
Exosomal DNAJB11 promotes the development of pancreatic cancer by modulating the EGFR/MAPK pathway.
Liu P, Zu F, Chen H, Yin X, Tan X
Cellular & molecular biology letters 2022 Oct 8;27(1):87
Cellular & molecular biology letters 2022 Oct 8;27(1):87
CircRNF144B/miR-342-3p/FBXL11 axis reduced autophagy and promoted the progression of ovarian cancer by increasing the ubiquitination of Beclin-1.
Song W, Zeng Z, Zhang Y, Li H, Cheng H, Wang J, Wu F
Cell death & disease 2022 Oct 8;13(10):857
Cell death & disease 2022 Oct 8;13(10):857
Discovery of an autophagy inducer J3 to lower mutant huntingtin and alleviate Huntington's disease-related phenotype.
Long J, Luo X, Fang D, Song H, Fang W, Shan H, Liu P, Lu B, Yin XM, Hong L, Li M
Cell & bioscience 2022 Oct 8;12(1):167
Cell & bioscience 2022 Oct 8;12(1):167
An alternative mechanism for skeletal muscle dysfunction in long-term post-viral lung disease.
Martin RA, Keeler SP, Wu K, Shearon WJ, Patel D, Hoang M, Hoffmann CM, Hughes ME, Holtzman MJ
bioRxiv : the preprint server for biology 2022 Oct 8;
bioRxiv : the preprint server for biology 2022 Oct 8;
Generation of Flag/DYKDDDDK Epitope Tag Knock-In Mice Using i-GONAD Enables Detection of Endogenous CaMKIIα and β Proteins.
Aoto K, Takabayashi S, Mutoh H, Saitsu H
International journal of molecular sciences 2022 Oct 7;23(19)
International journal of molecular sciences 2022 Oct 7;23(19)
A20 Enhances the Expression of the Proto-Oncogene C-Myc by Downregulating TRAF6 Ubiquitination after ALV-A Infection.
Chen X, Wang X, Yang Y, Fang C, Liu J, Liang X, Yang Y
Viruses 2022 Oct 7;14(10)
Viruses 2022 Oct 7;14(10)
Association of lithocholic acid with skeletal muscle hypertrophy through TGR5-IGF-1 and skeletal muscle mass in cultured mouse myotubes, chronic liver disease rats and humans.
Tamai Y, Eguchi A, Shigefuku R, Kitamura H, Tempaku M, Sugimoto R, Kobayashi Y, Iwasa M, Takei Y, Nakagawa H
eLife 2022 Oct 7;11
eLife 2022 Oct 7;11
The retracted conformation of ubiquitin Ser65 phosphorylation inhibits the formation of K48-linked ubiquitin chains.
Zhang CL, Wang XM, Yang J, Xin CQ, Fan W, Yi HW
Bioscience reports 2022 Oct 7;
Bioscience reports 2022 Oct 7;
Necrostatin-1 Alleviates Lung Ischemia-Reperfusion Injury via Inhibiting Necroptosis and Apoptosis of Lung Epithelial Cells.
Dong L, Liang F, Lou Z, Li Y, Li J, Chen Y, Ding J, Jiang B, Wu C, Yu H, Liu Y, Zhang W, Lu Y, Wu M
Cells 2022 Oct 6;11(19)
Cells 2022 Oct 6;11(19)
Self-amplifying loop of NF-κB and periostin initiated by PIEZO1 accelerates mechano-induced senescence of nucleus pulposus cells and intervertebral disc degeneration.
Wu J, Chen Y, Liao Z, Liu H, Zhang S, Zhong D, Qiu X, Chen T, Su D, Ke X, Wan Y, Zhou T, Su P
Molecular therapy : the journal of the American Society of Gene Therapy 2022 Oct 5;30(10):3241-3256
Molecular therapy : the journal of the American Society of Gene Therapy 2022 Oct 5;30(10):3241-3256
circRNA422 enhanced osteogenic differentiation of bone marrow mesenchymal stem cells during early osseointegration through the SP7/LRP5 axis.
Yu K, Jiang Z, Miao X, Yu Z, Du X, Lai K, Wang Y, Yang G
Molecular therapy : the journal of the American Society of Gene Therapy 2022 Oct 5;30(10):3226-3240
Molecular therapy : the journal of the American Society of Gene Therapy 2022 Oct 5;30(10):3226-3240
Identification of CPT2 as a prognostic biomarker by integrating the metabolism-associated gene signature in colorectal cancer.
Liu J, Li Y, Xiao Q, Li Y, Peng Y, Gan Y, Shu G, Yi H, Yin G
BMC cancer 2022 Oct 4;22(1):1038
BMC cancer 2022 Oct 4;22(1):1038
Inhibition of Schwann cell pannexin 1 attenuates neuropathic pain through the suppression of inflammatory responses.
Wang Q, Li HY, Ling ZM, Chen G, Wei ZY
Journal of neuroinflammation 2022 Oct 4;19(1):244
Journal of neuroinflammation 2022 Oct 4;19(1):244
Upregulation of CRABP2 by TET1-mediated DNA hydroxymethylation attenuates mitochondrial apoptosis and promotes oxaliplatin resistance in gastric cancer.
Tang X, Liang Y, Sun G, He Q, Hou Z, Jiang X, Gao P, Qu H
Cell death & disease 2022 Oct 4;13(10):848
Cell death & disease 2022 Oct 4;13(10):848
NOP53 undergoes liquid-liquid phase separation and promotes tumor radio-resistance.
Shi J, Chen SY, Shen XT, Yin XK, Zhao WW, Bai SM, Feng WX, Feng LL, Qin C, Zheng J, Wang YL, Fan XJ
Cell death discovery 2022 Oct 31;8(1):436
Cell death discovery 2022 Oct 31;8(1):436
Inhibition of Netosis with PAD Inhibitor Attenuates Endotoxin Shock Induced Systemic Inflammation.
Yao H, Cao G, Liu Z, Zhao Y, Yan Z, Wang S, Wang Y, Guo Z, Wang Y
International journal of molecular sciences 2022 Oct 31;23(21)
International journal of molecular sciences 2022 Oct 31;23(21)
Z. morio Hemolymph Relieves E. coli-Induced Mastitis by Inhibiting Inflammatory Response and Repairing the Blood-Milk Barrier.
Zou Y, Wang X, Xu J, Wang S, Li S, Zhu Y, Wang J
International journal of molecular sciences 2022 Oct 31;23(21)
International journal of molecular sciences 2022 Oct 31;23(21)
Rspondin-1 contributes to the progression and stemness of gastric cancer by LGR5.
Wang C, Gao Y, Liang W, Lu Y, Zhang K, Wu D, Zhuang Z, Li K, Qiao Z, Xi H, Chen L
Biochemical and biophysical research communications 2022 Oct 30;627:91-96
Biochemical and biophysical research communications 2022 Oct 30;627:91-96
TRAF4 promotes the malignant progression of high-grade serous ovarian cancer by activating YAP pathway.
Luo X, Cao J, Zhang C, Huang H, Liu J
Biochemical and biophysical research communications 2022 Oct 30;627:68-75
Biochemical and biophysical research communications 2022 Oct 30;627:68-75
Paraquat is an agonist of STIM1 and increases intracellular calcium levels.
Yang W, Tian R, Zhu Y, Huang P, Ma X, Meng X, Dai W, Tao Y, Chen D, Zhang J, Lu J, Xie H, Jian X, Yang Z, Wang R
Communications biology 2022 Oct 30;5(1):1151
Communications biology 2022 Oct 30;5(1):1151
Interferon-Inducible Transmembrane Protein 3 (IFITM3) Restricts Rotavirus Infection.
Pang Z, Hao P, Qu Q, Li L, Jiang Y, Xiao S, Jin N, Li C
Viruses 2022 Oct 30;14(11)
Viruses 2022 Oct 30;14(11)
VAMP4 regulates insulin levels by targeting secretory granules to lysosomes.
Li M, Feng F, Feng H, Hu P, Xue Y, Xu T, Song E
The Journal of cell biology 2022 Oct 3;221(10)
The Journal of cell biology 2022 Oct 3;221(10)
Impaired XK recycling for importing manganese underlies striatal vulnerability in Huntington's disease.
Chhetri G, Ke Y, Wang P, Usman M, Li Y, Sapp E, Wang J, Ghosh A, Islam MA, Wang X, Boudi A, DiFiglia M, Li X
The Journal of cell biology 2022 Oct 3;221(10)
The Journal of cell biology 2022 Oct 3;221(10)
Fucoxanthin induces apoptosis and reverses epithelial-mesenchymal transition via inhibiting Wnt/β-catenin pathway in lung adenocarcinoma.
Luan H, Yan L, Zhao Y, Ding X, Cao L
Discover oncology 2022 Oct 3;13(1):98
Discover oncology 2022 Oct 3;13(1):98
An optimized exosome production strategy for enhanced yield while without sacrificing cargo loading efficiency.
Zhang R, Bu T, Cao R, Li Z, Wang C, Huang B, Wei M, Yuan L, Yang G
Journal of nanobiotechnology 2022 Oct 29;20(1):463
Journal of nanobiotechnology 2022 Oct 29;20(1):463
Knockdown of METTL16 disrupts learning and memory by reducing the stability of MAT2A mRNA.
Zhang R, Zhang Y, Guo F, Huang G, Zhao Y, Chen B, Wang C, Cui C, Shi Y, Li S, Cui H
Cell death discovery 2022 Oct 28;8(1):432
Cell death discovery 2022 Oct 28;8(1):432
ITGA2 overexpression inhibits DNA repair and confers sensitivity to radiotherapies in pancreatic cancer.
Zhou C, Li S, Bin K, Qin G, Pan P, Ren D, Zhao Y, Xia W, Chen J, Liu J, Wu H, Zhou Y
Cancer letters 2022 Oct 28;547:215855
Cancer letters 2022 Oct 28;547:215855
Peimine ameliorates pulmonary fibrosis via the inhibition of M2-type macrophage polarization through the suppression of P38/Akt/STAT6 signals.
Cai ZH, Tian YG, Li JZ, Zhao P, Li JS, Mei X, Bai YP
Bioscience reports 2022 Oct 28;42(10)
Bioscience reports 2022 Oct 28;42(10)
MICALL2 as a substrate of ubiquitinase TRIM21 regulates tumorigenesis of colorectal cancer.
Wen P, Wang H, Li Y, Sui X, Hou Z, Guo X, Xue W, Liu D, Wang Y, Gao J
Cell communication and signaling : CCS 2022 Oct 28;20(1):170
Cell communication and signaling : CCS 2022 Oct 28;20(1):170
Arrest of Cell Cycle by Avian Reovirus p17 through Its Interaction with Bub3.
Tang J, Fu M, Chen X, Zhao Y, Gao L, Cao H, Li X, Zheng SJ, Wang Y
Viruses 2022 Oct 28;14(11)
Viruses 2022 Oct 28;14(11)
Extracellular vesicles microRNA-592 of melanoma stem cells promotes metastasis through activation of MAPK/ERK signaling pathway by targeting PTPN7 in non-stemness melanoma cells.
Zhang Y, Chen Y, Shi L, Li J, Wan W, Li B, Liu D, Li X, Chen Y, Xiang M, Chen H, Zeng B, Xing HR, Wang J
Cell death discovery 2022 Oct 27;8(1):428
Cell death discovery 2022 Oct 27;8(1):428
Inhibition of SRPK1, a key splicing regulator, exhibits antitumor and chemotherapeutic-sensitizing effects on extranodal NK/T-cell lymphoma cells.
He C, Liu B, Wang HY, Wu L, Zhao G, Huang C, Liu Y, Shan B, Liu L
BMC cancer 2022 Oct 27;22(1):1100
BMC cancer 2022 Oct 27;22(1):1100
Calcium transients on the ER surface trigger liquid-liquid phase separation of FIP200 to specify autophagosome initiation sites.
Zheng Q, Chen Y, Chen D, Zhao H, Feng Y, Meng Q, Zhao Y, Zhang H
Cell 2022 Oct 27;185(22):4082-4098.e22
Cell 2022 Oct 27;185(22):4082-4098.e22
An assembly-inducing PDC enabling the efficient nuclear delivery of nucleic acid for cancer stem-like cell suppression.
Wang D, Tian Y, Zhang Y, Sun X, Wu Y, Liu R, Zeng F, Du J, Hu K
Nanoscale 2022 Oct 27;14(41):15384-15392
Nanoscale 2022 Oct 27;14(41):15384-15392
Jian-Pi-Yi-Shen decoction inhibits mitochondria-dependent granulosa cell apoptosis in a rat model of POF.
Jiang XL, Tai H, Kuang JS, Zhang JY, Cui SC, Lu YX, Qi SB, Zhang SY, Li SM, Chen JP, Meng XS
Aging 2022 Oct 27;14(20):8321-8345
Aging 2022 Oct 27;14(20):8321-8345
Senescent neutrophils-derived exosomal piRNA-17560 promotes chemoresistance and EMT of breast cancer via FTO-mediated m6A demethylation.
Ou B, Liu Y, Gao Z, Xu J, Yan Y, Li Y, Zhang J
Cell death & disease 2022 Oct 27;13(10):905
Cell death & disease 2022 Oct 27;13(10):905
Oral Microbiota from Periodontitis Promote Oral Squamous Cell Carcinoma Development via γδ T Cell Activation.
Wei W, Li J, Shen X, Lyu J, Yan C, Tang B, Ma W, Xie H, Zhao L, Cheng L, Deng Y, Li Y
mSystems 2022 Oct 26;7(5):e0046922
mSystems 2022 Oct 26;7(5):e0046922
GSK872 and necrostatin-1 protect retinal ganglion cells against necroptosis through inhibition of RIP1/RIP3/MLKL pathway in glutamate-induced retinal excitotoxic model of glaucoma.
Liu M, Li H, Yang R, Ji D, Xia X
Journal of neuroinflammation 2022 Oct 26;19(1):262
Journal of neuroinflammation 2022 Oct 26;19(1):262
Multi-omics characterization of autophagy-related molecular features for therapeutic targeting of autophagy.
Luo M, Ye L, Chang R, Ye Y, Zhang Z, Liu C, Li S, Jing Y, Ruan H, Zhang G, He Y, Liu Y, Xue Y, Chen X, Guo AY, Liu H, Han L
Nature communications 2022 Oct 26;13(1):6345
Nature communications 2022 Oct 26;13(1):6345
ACSL1 promotes imatinib-induced chronic myeloid leukemia cell senescence by regulating SIRT1/p53/p21 pathway.
Liu W, Zhu X, Tang L, Shen N, Cheng F, Zou P, You Y, Yuan G, Li Q, Zhu X
Scientific reports 2022 Oct 26;12(1):17990
Scientific reports 2022 Oct 26;12(1):17990
ER-phagy Is Involved in the Degradation of Collagen I by IL-1β in Human Amnion in Parturition.
Mi YB, Liu XH, Wang WS, Wang LY, Ling LJ, Sun K, Ying H
Journal of immunology (Baltimore, Md. : 1950) 2022 Oct 26;
Journal of immunology (Baltimore, Md. : 1950) 2022 Oct 26;
m(6)A modification confers thermal vulnerability to HPV E7 oncotranscripts via reverse regulation of its reader protein IGF2BP1 upon heat stress.
Wang L, Zhan G, Maimaitiyiming Y, Su Y, Lin S, Liu J, Su K, Lin J, Shen S, He W, Wang F, Chen J, Sun S, Xue Y, Gu J, Chen X, Zhang J, Zhang L, Wang Q, Chang KJ, Chiou SH, Björklund M, Naranmandura H, Cheng X, Hsu CH
Cell reports 2022 Oct 25;41(4):111546
Cell reports 2022 Oct 25;41(4):111546
Circulating small extracellular vesicle-encapsulated SEMA5A-IT1 attenuates myocardial ischemia-reperfusion injury after cardiac surgery with cardiopulmonary bypass.
Wu T, Shi G, Ji Z, Wang S, Geng L, Guo Z
Cellular & molecular biology letters 2022 Oct 25;27(1):95
Cellular & molecular biology letters 2022 Oct 25;27(1):95
LncRNA LINC01537 Promotes Gastric Cancer Metastasis and Tumorigenesis by Stabilizing RIPK4 to Activate NF-κB Signaling.
Zhong GY, Tan JN, Huang J, Zhou SN, Yu JH, Zhong L, Hou D, Zhi SL, Zeng JT, Li HM, Zheng CL, Yang B, Han FH
Cancers 2022 Oct 25;14(21)
Cancers 2022 Oct 25;14(21)
Metabolic Responses and Pathway Changes of Vero Cells under High-Vitamin B Medium.
Yu S, Yan J, Yang Z, Zhao Y, Wang H, Yang X
Vaccines 2022 Oct 25;10(11)
Vaccines 2022 Oct 25;10(11)
Schwann cells-derived exosomal miR-21 participates in high glucose regulation of neurite outgrowth.
Liu YP, Tian MY, Yang YD, Li H, Zhao TT, Zhu J, Mou FF, Cui GH, Guo HD, Shao SJ
iScience 2022 Oct 21;25(10):105141
iScience 2022 Oct 21;25(10):105141
Induced retinal pigment epithelial cells with anti-epithelial-to-mesenchymal transition ability delay retinal degeneration.
Tian H, Chen Z, Zhu X, Ou Q, Wang Z, Wu B, Xu JY, Jin C, Gao F, Wang J, Zhang J, Zhang J, Lu L, Xu GT
iScience 2022 Oct 21;25(10):105050
iScience 2022 Oct 21;25(10):105050
Single cell transcriptomic profiling of a neuron-astrocyte assembloid tauopathy model.
Rickner HD, Jiang L, Hong R, O'Neill NK, Mojica CA, Snyder BJ, Zhang L, Shaw D, Medalla M, Wolozin B, Cheng CS
Nature communications 2022 Oct 21;13(1):6275
Nature communications 2022 Oct 21;13(1):6275
Renoprotective effect of Tanshinone IIA against kidney injury induced by ischemia-reperfusion in obese rats.
Tai H, Cui XZ, He J, Lan ZM, Li SM, Li LB, Yao SC, Jiang XL, Meng XS, Kuang JS
Aging 2022 Oct 20;14(20):8302-8320
Aging 2022 Oct 20;14(20):8302-8320
In Vitro and In Vivo Evaluation of Antidiabetic Properties and Mechanisms of Ficus tikoua Bur.
Wang H, Zhang K, Chen X, Han M, Lu J, Zhang Y
Nutrients 2022 Oct 20;14(20)
Nutrients 2022 Oct 20;14(20)
PDCL2 is essential for spermiogenesis and male fertility in mice.
Li M, Chen Y, Ou J, Huang J, Zhang X
Cell death discovery 2022 Oct 17;8(1):419
Cell death discovery 2022 Oct 17;8(1):419
Trilobatin alleviates non-alcoholic fatty liver disease in high-fat diet plus streptozotocin-induced diabetic mice by suppressing NLRP3 inflammasome activation.
Zhang ZT, He WJ, Deng SM, Xu SH, Zeng X, Qian ZM, Chen ZQ, Wang SM, Tang D
European journal of pharmacology 2022 Oct 15;933:175291
European journal of pharmacology 2022 Oct 15;933:175291
p-TAK1 acts as a switch between myoblast proliferation phase and differentiation phase in mdx mice via regulating HO-1 expression.
Fan S, Huang X, Tong H, Hong H, Lai Z, Hu W, Liu X, Zhang L, Jiang Z, Yu Q
European journal of pharmacology 2022 Oct 15;933:175277
European journal of pharmacology 2022 Oct 15;933:175277
Malvidin protects against lipopolysaccharide-induced acute liver injury in mice via regulating Nrf2 and NLRP3 pathways and suppressing apoptosis and autophagy.
Fan H, Cui J, Liu F, Zhang W, Yang H, He N, Dong Z, Dong J
European journal of pharmacology 2022 Oct 15;933:175252
European journal of pharmacology 2022 Oct 15;933:175252
αSMA-Cre-mediated Ogt deletion leads to heart failure and vascular smooth muscle cell dysfunction in mice.
Xiong X, Ma H, Ma J, Wang X, Li D, Xu L
Biochemical and biophysical research communications 2022 Oct 15;625:31-37
Biochemical and biophysical research communications 2022 Oct 15;625:31-37
Mitophagy induced by classical swine fever virus nonstructural protein 5A promotes viral replication.
Chengcheng Z, Xiuling W, Jiahao S, Mengjiao G, Xiaorong Z, Yantao W
Virus research 2022 Oct 15;320:198886
Virus research 2022 Oct 15;320:198886
Role of RNA m(6)A modification in titanium dioxide nanoparticle-induced acute pulmonary injury: An in vitro and in vivo study.
Ruan F, Liu C, Wang Y, Cao X, Tang Z, Xu J, Zeng J, Yin H, Zheng N, Yang C, Zuo Z, He C
Environmental pollution (Barking, Essex : 1987) 2022 Oct 15;311:119986
Environmental pollution (Barking, Essex : 1987) 2022 Oct 15;311:119986
Obeticholic acid aggravates liver injury by up-regulating the liver expression of osteopontin in obstructive cholestasis.
Wang J, Yuan Z, Zhang H, Wu Q, Miao Y, Xu Y, Yu Q, Huang X, Zhang Z, Huang X, Tang Q, Zhang L, Jiang Z
Life sciences 2022 Oct 15;307:120882
Life sciences 2022 Oct 15;307:120882
Transcriptional factor III A promotes colorectal cancer progression by upregulating cystatin A.
Wang J, Tan Y, Jia QY, Tang FQ
World journal of gastrointestinal oncology 2022 Oct 15;14(10):1918-1932
World journal of gastrointestinal oncology 2022 Oct 15;14(10):1918-1932
Subcellular partitioning of protein kinase activity revealed by functional kinome profiling.
Wegman-Points L, Alganem K, Imami AS, Mathis V, Creeden JF, McCullumsmith R, Yuan LL
Scientific reports 2022 Oct 15;12(1):17300
Scientific reports 2022 Oct 15;12(1):17300
CLDN1 Sensitizes Triple-Negative Breast Cancer Cells to Chemotherapy.
Lemesle M, Geoffroy M, Alpy F, Tomasetto CL, Kuntz S, Grillier-Vuissoz I
Cancers 2022 Oct 14;14(20)
Cancers 2022 Oct 14;14(20)
DAZAP1 facilitates the alternative splicing of KITLG to promote multiple myeloma cell proliferation via ERK signaling pathway.
Zhou Y, Huangfu S, Li M, Tang C, Qian J, Guo M, Zhou Z, Yang Y, Gu C
Aging 2022 Oct 13;14(19):7972-7985
Aging 2022 Oct 13;14(19):7972-7985
Melatonin Prevents against Ethanol-Induced Liver Injury by Mitigating Ferroptosis via Targeting Brain and Muscle ARNT-like 1 in Mice Liver and HepG2 Cells.
Zhao Y, Zhang R, Wang Z, Chen Z, Wang G, Guan S, Lu J
Journal of agricultural and food chemistry 2022 Oct 12;70(40):12953-12967
Journal of agricultural and food chemistry 2022 Oct 12;70(40):12953-12967
Targeting UBR5 in hepatocellular carcinoma cells and precise treatment via echinacoside nanodelivery.
Wang M, Ma X, Wang G, Song Y, Zhang M, Mai Z, Zhou B, Ye Y, Xia W
Cellular & molecular biology letters 2022 Oct 12;27(1):92
Cellular & molecular biology letters 2022 Oct 12;27(1):92
STING pathway contributes to the prognosis of hepatocellular carcinoma and identification of prognostic gene signatures correlated to tumor microenvironment.
Pu Z, Liu J, Liu Z, Peng F, Zhu Y, Wang X, He J, Yi P, Hu X, Fan X, Chen J
Cancer cell international 2022 Oct 12;22(1):314
Cancer cell international 2022 Oct 12;22(1):314
Targeting EGFR-dependent tumors by disrupting an ARF6-mediated sorting system.
Guo H, Wang J, Ren S, Zheng LF, Zhuang YX, Li DL, Sun HH, Liu LY, Xie C, Wu YY, Wang HR, Deng X, Li P, Zhao TJ
Nature communications 2022 Oct 12;13(1):6004
Nature communications 2022 Oct 12;13(1):6004
PSD-95 in the anterior cingulate cortex contributes to neuropathic pain by interdependent activation with NR2B.
Li A, Huang CJ, Gu KP, Huang Y, Huang YQ, Zhang H, Lin JP, Liu YF, Yang Y, Yao YX
Scientific reports 2022 Oct 12;12(1):17114
Scientific reports 2022 Oct 12;12(1):17114
Vimentin inhibits type I interferon production by disrupting the TBK1-IKKε-IRF3 axis.
Liu H, Ye G, Liu X, Xue M, Zhou Q, Zhang L, Zhang K, Huang L, Weng C
Cell reports 2022 Oct 11;41(2):111469
Cell reports 2022 Oct 11;41(2):111469
LARRPM restricts lung adenocarcinoma progression and M2 macrophage polarization through epigenetically regulating LINC00240 and CSF1.
Li Y, Chen C, Liu HL, Zhang ZF, Wang CL
Cellular & molecular biology letters 2022 Oct 11;27(1):91
Cellular & molecular biology letters 2022 Oct 11;27(1):91
Jatrorrhizine Improves Endothelial Function in Diabetes and Obesity through Suppression of Endoplasmic Reticulum Stress.
Zhou Y, Wang Y, Vong CT, Zhu Y, Xu B, Ruan CC, Wang Y, Cheang WS
International journal of molecular sciences 2022 Oct 11;23(20)
International journal of molecular sciences 2022 Oct 11;23(20)
CGG repeat expansion in NOTCH2NLC causes mitochondrial dysfunction and progressive neurodegeneration in Drosophila model.
Yu J, Liufu T, Zheng Y, Xu J, Meng L, Zhang W, Yuan Y, Hong D, Charlet-Berguerand N, Wang Z, Deng J
Proceedings of the National Academy of Sciences of the United States of America 2022 Oct 11;119(41):e2208649119
Proceedings of the National Academy of Sciences of the United States of America 2022 Oct 11;119(41):e2208649119
ISG20L2 suppresses bortezomib antimyeloma activity by attenuating bortezomib binding to PSMB5.
Yang Y, Gao Y, Huang J, Yang Z, Luo H, Wang F, Xu J, Cui Y, Ding H, Lin Z, Zhai X, Qu Y, Zhang L, Liu T, Ye L, Niu T, Zheng Y
JCI insight 2022 Oct 10;7(19)
JCI insight 2022 Oct 10;7(19)
Micronuclei from misaligned chromosomes that satisfy the spindle assembly checkpoint in cancer cells.
Gomes AM, Orr B, Novais-Cruz M, De Sousa F, Macário-Monteiro J, Lemos C, Ferrás C, Maiato H
Current biology : CB 2022 Oct 10;32(19):4240-4254.e5
Current biology : CB 2022 Oct 10;32(19):4240-4254.e5
RAI14 Promotes Melanoma Progression by Regulating the FBXO32/c-MYC Pathway.
Xu J, Shi P, Xia F, Zhao X, Chen J, Geng R, Cui H, Yang L
International journal of molecular sciences 2022 Oct 10;23(19)
International journal of molecular sciences 2022 Oct 10;23(19)
Neurogranin inhibits calcineurin in murine soleus muscle: Effects of heterozygous knockdown on muscle adaptations to tenotomy and fatigue resistance.
Baranowski RW, Braun JL, Vandenboom R, Fajardo VA
Biochemical and biophysical research communications 2022 Oct 1;623:89-95
Biochemical and biophysical research communications 2022 Oct 1;623:89-95
The matrix protein of Newcastle disease virus inhibits inflammatory response through IRAK4/TRAF6/TAK1/NF-κB signaling pathway.
Duan Z, Xing J, Shi H, Wang Y, Zhao C
International journal of biological macromolecules 2022 Oct 1;218:295-309
International journal of biological macromolecules 2022 Oct 1;218:295-309
Influence of Boron Neutron Capture Therapy on Normal Liver Tissue.
Tamari Y, Takata T, Takeno S, Tanaka H, Yamazaki H, Yamada K, Suzuki M
Radiation research 2022 Oct 1;198(4):368-374
Radiation research 2022 Oct 1;198(4):368-374
Inactivation of fatty acid amide hydrolase protects against ischemic reperfusion injury-induced renal fibrogenesis.
Chen C, Wang W, Poklis JL, Lichtman AH, Ritter JK, Hu G, Xie D, Li N
Biochimica et biophysica acta. Molecular basis of disease 2022 Oct 1;1868(10):166456
Biochimica et biophysica acta. Molecular basis of disease 2022 Oct 1;1868(10):166456
Locomotor Hyperactivity in the Early-Stage Alzheimer's Disease-like Pathology of APP/PS1 Mice: Associated with Impaired Polarization of Astrocyte Aquaporin 4.
Wang T, Chen Y, Zou Y, Pang Y, He X, Chen Y, Liu Y, Feng W, Zhang Y, Li Q, Shi J, Ding F, Marshall C, Gao J, Xiao M
Aging and disease 2022 Oct 1;13(5):1504-1522
Aging and disease 2022 Oct 1;13(5):1504-1522
UPP1 Promotes Lung Adenocarcinoma Progression through Epigenetic Regulation of Glycolysis.
Wang X, Wang Z, Huang R, Lu Z, Chen X, Huang D
Aging and disease 2022 Oct 1;13(5):1488-1503
Aging and disease 2022 Oct 1;13(5):1488-1503
Role of estrogen receptors in thyroid toxicity induced by mono (2-ethylhexyl) phthalate via endoplasmic reticulum stress: An in vitro mechanistic investigation.
Xu Q, Zhou L, Ri H, Li X, Zhang X, Qi W, Ye L
Environmental toxicology and pharmacology 2022 Nov;96:104007
Environmental toxicology and pharmacology 2022 Nov;96:104007
Blood-brain barrier permeability to enrofloxacin in Pengze crucian carp (Carassius auratus var. Pengze).
Zhang F, Wang R, Huang J, Zhang H, Wang L, Zhong Z, Ruan J, Liu H
Veterinary medicine and science 2022 Nov;8(6):2404-2410
Veterinary medicine and science 2022 Nov;8(6):2404-2410
SENP3 Aggravates Renal Tubular Epithelial Cell Apoptosis in Lipopolysaccharide-Induced Acute Kidney Injury via deSUMOylation of Drp1.
Wang L, Li J, Yu C
Kidney diseases (Basel, Switzerland) 2022 Nov;8(5):424-435
Kidney diseases (Basel, Switzerland) 2022 Nov;8(5):424-435
Plasma exosomal miR-122 regulates the efficacy of metformin via AMPK in type 2 diabetes and hepatocellular carcinoma.
Peng H, Hou M, Wu Z, Wang J, Zhou M, Zhuang X, Xing J, Tao Q, Huang L, Zhou F, Zhang S, Feng Q, Hou Y, Yu Q
Heliyon 2022 Nov;8(11):e11503
Heliyon 2022 Nov;8(11):e11503
Tumor suppressor LHPP suppresses cell proliferation and epithelial-mesenchymal transition in hepatocellular carcinoma cell lines.
Ma L, Sun H, Xu X, Chen Y, Zhang L, Li S, Tang L
Journal of physiology and biochemistry 2022 Nov;78(4):807-817
Journal of physiology and biochemistry 2022 Nov;78(4):807-817
Orphan nuclear receptor NUR77 relieves insulin resistance in HTR-8/SVneo trophoblast cells through activation of autophagy and insulin signaling.
Li L, Bai Y, Du R, Tang L, Li L
Journal of physiology and biochemistry 2022 Nov;78(4):777-791
Journal of physiology and biochemistry 2022 Nov;78(4):777-791
In vivo fluorescent screening for HPPD-targeted herbicide discovery.
Fu YX, Zhang ZY, Guo WY, Dai YJ, Wang ZY, Yang WC, Yang GF
Pest management science 2022 Nov;78(11):4947-4955
Pest management science 2022 Nov;78(11):4947-4955
Proteomic analysis and identification reveal the anti-inflammatory mechanism of clofazimine on lipopolysaccharide-induced acute lung injury in mice.
Yang B, Gao Z, Li QS, Zhang XY, Song L, Wang YN, Wang XY, Ji LL, Xu HL, Xie H, Feng FK, Li XP, Li W, Wang R, Wang GS
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2022 Nov;71(10-11):1327-1345
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2022 Nov;71(10-11):1327-1345
Identification of a Feed-Forward Loop Between 15(S)-HETE and PGE2 in Human Amnion at Parturition.
Zhang F, Sun K, Wang WS
Journal of lipid research 2022 Nov;63(11):100294
Journal of lipid research 2022 Nov;63(11):100294
Subtype-specific 3D genome alteration in acute myeloid leukaemia.
Xu J, Song F, Lyu H, Kobayashi M, Zhang B, Zhao Z, Hou Y, Wang X, Luan Y, Jia B, Stasiak L, Wong JH, Wang Q, Jin Q, Jin Q, Fu Y, Yang H, Hardison RC, Dovat S, Platanias LC, Diao Y, Yang Y, Yamada T, Viny AD, Levine RL, Claxton D, Broach JR, Zheng H, Yue F
Nature 2022 Nov;611(7935):387-398
Nature 2022 Nov;611(7935):387-398
Selenoprotein K contributes to CD36 subcellular trafficking in hepatocytes by accelerating nascent COPII vesicle formation and aggravates hepatic steatosis.
You M, Wu F, Gao M, Chen M, Zeng S, Zhang Y, Zhao W, Li D, Wei L, Ruan XZ, Chen Y
Redox biology 2022 Nov;57:102500
Redox biology 2022 Nov;57:102500
Hypotonic induction of aquaporin5 expression in rat astrocytes through p38 MAPK pathway.
Yi Y, Qiu G, Liu H, Gao F, Liu X, Chen Y, Yang M
Anatomia, histologia, embryologia 2022 Nov;51(6):769-780
Anatomia, histologia, embryologia 2022 Nov;51(6):769-780
Lack of bombesin receptor-activated protein attenuates bleomycin-induced pulmonary fibrosis in mice.
Wang H, Zhang W, Liu R, Zheng J, Yao X, Chen H, Wang J, Weber HC, Qin X, Xiang Y, Liu C, Liu H, Pan L, Qu X
Life science alliance 2022 Nov;5(11)
Life science alliance 2022 Nov;5(11)
Atypical chemokine receptor 3 induces colorectal tumorigenesis in mice by promoting β-arrestin-NOLC1-fibrillarin-dependent rRNA biogenesis.
Yang J, Miao RR, Li YN, Pan T, Wu SH, Qu XJ, Cui SX
Acta pharmacologica Sinica 2022 Nov;43(11):2967-2976
Acta pharmacologica Sinica 2022 Nov;43(11):2967-2976
Intratracheal instillation of graphene oxide decreases anti-virus responses and lipid contents via suppressing Toll-like receptor 3 in mouse livers.
Tang X, Song F, Zhao W, Zhang Z, Cao Y
Journal of applied toxicology : JAT 2022 Nov;42(11):1822-1831
Journal of applied toxicology : JAT 2022 Nov;42(11):1822-1831
Metformin suppresses vascular smooth muscle cell senescence by promoting autophagic flux.
Tai S, Sun J, Zhou Y, Zhu Z, He Y, Chen M, Yang H, Xiao Y, Tu T, Tang L, Li X, Zeng J, Zheng X, Zhou S
Journal of advanced research 2022 Nov;41:205-218
Journal of advanced research 2022 Nov;41:205-218
The ubiquitin-specific protease 8 antagonizes melatonin-induced endocytic degradation of MT(1) receptor to promote lung adenocarcinoma growth.
Sun Q, Zhang J, Li X, Yang G, Cheng S, Guo D, Zhang Q, Sun F, Zhao F, Yang D, Wang S, Wang T, Liu S, Zou L, Zhang Y, Liu H
Journal of advanced research 2022 Nov;41:1-12
Journal of advanced research 2022 Nov;41:1-12
Selenium-sensitive histone deacetylase 2 is required for forkhead box O3A and regulates extracellular matrix metabolism in cartilage.
Zhao Y, Guo Y, Sun M, Hussion S, Zheng Y, Huang H, Huo X, Zhao Y, Zhang F, Han Y, Ning Q, Xu P, Sun J, Lu S
Journal of bone and mineral metabolism 2022 Nov;40(6):914-926
Journal of bone and mineral metabolism 2022 Nov;40(6):914-926
GRAP2 is a prognostic biomarker and correlated with immune infiltration in lung adenocarcinoma.
Song S, Deng X, Jiang S, Tian C, Han J, Chai J, Li N, Yan Y, Luo Z
Journal of clinical laboratory analysis 2022 Nov;36(11):e24662
Journal of clinical laboratory analysis 2022 Nov;36(11):e24662
circBGN accelerates gastric cancer cell proliferation and invasion via activating IL6/STAT3 signaling pathway.
Li C, Peng X, Peng Z, Yan B
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2022 Nov;36(11):e22604
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2022 Nov;36(11):e22604
Disturbing NLRP3 acetylation and inflammasome assembly inhibits androgen receptor-promoted inflammatory responses and prostate cancer progression.
Zhao AN, Yang Z, Wang DD, Shi B, Zhang H, Bai Y, Yan BW, Zhang Y, Wen JK, Wang XL, Qu CB
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2022 Nov;36(11):e22602
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2022 Nov;36(11):e22602
Berbamine hydrochloride inhibits bovine viral diarrhea virus replication via interfering in late-stage autophagy.
Wang J, Yang G, Zhang L, Zhang J, Wang J, Zou Y, Wang J
Virus research 2022 Nov;321:198905
Virus research 2022 Nov;321:198905
Chaperoning activity of the cyclophilin family prevents tau aggregation.
Hill SE, Esquivel AR, Ospina SR, Rahal LM, Dickey CA, Blair LJ
Protein science : a publication of the Protein Society 2022 Nov;31(11):e4448
Protein science : a publication of the Protein Society 2022 Nov;31(11):e4448
p38α in the preoptic area inhibits brown adipose tissue thermogenesis.
Wang J, Wu S, Zhan H, Bi W, Xu Y, Liang Y, Ge Y, Peng L, Jin X, Lu K, Zhao J, Gao L, He Z
Obesity (Silver Spring, Md.) 2022 Nov;30(11):2242-2255
Obesity (Silver Spring, Md.) 2022 Nov;30(11):2242-2255
Aurora A-mediated pyruvate kinase M2 phosphorylation promotes biosynthesis with glycolytic metabolites and tumor cell cycle progression.
Jiang Y, Wang T, Sheng D, Han C, Xu T, Zhang P, You W, Fan W, Zhang Z, Jin T, Duan X, Yuan X, Liu X, Zhang K, Ruan K, Shi J, Guo J, Cheng A, Yang Z
The Journal of biological chemistry 2022 Nov;298(11):102561
The Journal of biological chemistry 2022 Nov;298(11):102561
Enhanced membrane binding of oncogenic G protein αqQ209L confers resistance to inhibitor YM-254890.
Randolph CE, Dwyer MB, Aumiller JL, Dixon AJ, Inoue A, Osei-Owusu P, Wedegaertner PB
The Journal of biological chemistry 2022 Nov;298(11):102538
The Journal of biological chemistry 2022 Nov;298(11):102538
Loss of RBMS1 promotes anti-tumor immunity through enabling PD-L1 checkpoint blockade in triple-negative breast cancer.
Zhang J, Zhang G, Zhang W, Bai L, Wang L, Li T, Yan L, Xu Y, Chen D, Gao W, Gao C, Chen C, Ren M, Jiao Y, Qin H, Sun Y, Zhi L, Qi Y, Zhao J, Liu Q, Liu H, Wang Y
Cell death and differentiation 2022 Nov;29(11):2247-2261
Cell death and differentiation 2022 Nov;29(11):2247-2261
Wnt/beta-catenin signaling confers ferroptosis resistance by targeting GPX4 in gastric cancer.
Wang Y, Zheng L, Shang W, Yang Z, Li T, Liu F, Shao W, Lv L, Chai L, Qu L, Xu Q, Du J, Liang X, Zeng J, Jia J
Cell death and differentiation 2022 Nov;29(11):2190-2202
Cell death and differentiation 2022 Nov;29(11):2190-2202
Molecular cloning, functional characterization of duck TRADD and its effect on infection with duck Tembusu virus.
Pan Y, Liu K, Huang J, Cheng A, Wang M, Chen S, Yang Q, Wu Y, Sun D, Mao S, Zhu D, Liu M, Zhao X, Zhang S, Gao Q, Ou X, Tian B, Yin Z, Jia R
Veterinary microbiology 2022 Nov;274:109573
Veterinary microbiology 2022 Nov;274:109573
African swine fever virus pE301R negatively regulates cGAS-STING signaling pathway by inhibiting the nuclear translocation of IRF3.
Liu X, Liu H, Ye G, Xue M, Yu H, Feng C, Zhou Q, Liu X, Zhang L, Jiao S, Weng C, Huang L
Veterinary microbiology 2022 Nov;274:109556
Veterinary microbiology 2022 Nov;274:109556
NOD2-mediated HDAC6/NF-κb signalling pathway regulates ferroptosis induced by extracellular histone H3 in acute liver failure.
Chen Q, Zhang Q, Cao P, Shi C, Zhang L, Wang L, Gong Z
Journal of cellular and molecular medicine 2022 Nov;26(21):5528-5538
Journal of cellular and molecular medicine 2022 Nov;26(21):5528-5538
Expression profile of immunoregulatory factors in canine tumors.
Murakami K, Miyatake S, Miyamae J, Saeki K, Shinya M, Akashi N, Mitsui I, Kobayashi K, Saeki K, Maeta N, Kanda T, Okamura Y, Hemmi H
Veterinary immunology and immunopathology 2022 Nov;253:110505
Veterinary immunology and immunopathology 2022 Nov;253:110505
Celastrol attenuates renal injury in 5/6 nephrectomized rats via inhibiting epithelial-mesenchymal transition and transforming growth factor-β1/Smad3 pathway.
Tang YW, Yang RC, Wan F, Tang XL, Zhang HQ, Lin Y
Experimental biology and medicine (Maywood, N.J.) 2022 Nov;247(21):1947-1955
Experimental biology and medicine (Maywood, N.J.) 2022 Nov;247(21):1947-1955
MG132 protects against lung injury following brain death in rats.
Shi H, Yang D, Huo Z, Li Y, Guo W, Zhang S
Experimental and therapeutic medicine 2022 Nov;24(5):687
Experimental and therapeutic medicine 2022 Nov;24(5):687
Chemerin promotes MAPK/ERK activation to induce inflammatory factor production in rat synoviocytes.
Wang C, Zhang S, Huang L, Liu J, Zhou Q, Du G, Lao S
Experimental and therapeutic medicine 2022 Nov;24(5):684
Experimental and therapeutic medicine 2022 Nov;24(5):684
Ac2‑26 alleviates hepatic ischemia‑reperfusion injury based on inhibiting the positive feedback loop of HMGB1/TLR4/NF‑κB/neutrophils.
Bai C, Jiang Z, Jiang H, Yu S, Li M, Chu F, Sheng Y, Li J, Jiang J, Li W
Experimental and therapeutic medicine 2022 Nov;24(5):673
Experimental and therapeutic medicine 2022 Nov;24(5):673
IL-17D-induced inhibition of DDX5 expression in keratinocytes amplifies IL-36R-mediated skin inflammation.
Ni X, Xu Y, Wang W, Kong B, Ouyang J, Chen J, Yan M, Wu Y, Chen Q, Wang X, Li H, Gao X, Guo H, Cui L, Chen Z, Shi Y, Zhu R, Li W, Shi T, Wang LF, Huang J, Dong C, Lai Y
Nature immunology 2022 Nov;23(11):1577-1587
Nature immunology 2022 Nov;23(11):1577-1587
Transcription factor NFE2L3 promotes the proliferation of esophageal squamous cell carcinoma cells and causes radiotherapy resistance by regulating IL-6.
Chen T, Xu B, Chen H, Sun Y, Song J, Sun X, Zhang X, Hua W
Computer methods and programs in biomedicine 2022 Nov;226:107102
Computer methods and programs in biomedicine 2022 Nov;226:107102
Legumain affects the PI3K/AKT tumor progression pathway in retinoblastoma.
Tang Q, Xu F, Lin J, Zhang C, Liu X, Dong L, Zhao J, Zhu L, Lin T
Experimental eye research 2022 Nov;224:109221
Experimental eye research 2022 Nov;224:109221
The effect and mechanistic study of encequidar on reversing the resistance of SW620/AD300 cells to doxorubicin.
Zhang H, Bian S, Xu Z, Gao M, Wang H, Zhang J, Zhang M, Ke Y, Wang W, Chen ZS, Xu H
Biochemical pharmacology 2022 Nov;205:115258
Biochemical pharmacology 2022 Nov;205:115258
Upstream stimulatory factor 2 inhibits erastin-induced ferroptosis in pancreatic cancer through transcriptional regulation of pyruvate kinase M2.
Chen M, Li X, Du B, Chen S, Li Y
Biochemical pharmacology 2022 Nov;205:115255
Biochemical pharmacology 2022 Nov;205:115255
Monoterpenoid indole alkaloid dimers from Kopsia arborea inhibit cyclin-dependent kinase 5 and tau phosphorylation.
Chen C, Liu JW, Guo LL, Xiong F, Ran XQ, Guo YR, Yao YG, Hao XJ, Luo RC, Zhang Y
Phytochemistry 2022 Nov;203:113392
Phytochemistry 2022 Nov;203:113392
Antifibrotic pyridine-containing monoterpene alkaloids from Caryopteris glutinosa.
Zhang X, Cao Y, Pan D, Yao X, Wang F, Zhang G, Luo Y
Phytochemistry 2022 Nov;203:113378
Phytochemistry 2022 Nov;203:113378
USP17L2-SIRT7 axis regulates DNA damage repair and chemoresistance in breast cancer cells.
Su Y, Wu C, Chang Y, Li L, Chen Y, Jia X, Wang X, Lv Y, Yu B, Yuan J
Breast cancer research and treatment 2022 Nov;196(1):31-44
Breast cancer research and treatment 2022 Nov;196(1):31-44
Exposure to Multiwall Carbon Nanotubes Promotes Fibrous Proliferation by Production of Matrix Metalloproteinase-12 via NF-κB Activation in Chronic Peritonitis.
Tsunematsu T, Arakaki R, Sato M, Saito M, Otsuka K, Furukawa Y, Taquahashi Y, Kanno J, Ishimaru N
The American journal of pathology 2022 Nov;192(11):1559-1572
The American journal of pathology 2022 Nov;192(11):1559-1572
Chromatin-remodeling factor BAZ1A/ACF1 targets UV damage sites in an MLL1-dependent manner to facilitate nucleotide excision repair.
Koyauchi T, Niida H, Motegi A, Sakai S, Uchida C, Ohhata T, Iijima K, Yokoyama A, Suda T, Kitagawa M
Biochimica et biophysica acta. Molecular cell research 2022 Nov;1869(11):119332
Biochimica et biophysica acta. Molecular cell research 2022 Nov;1869(11):119332
A novel oncotherapy strategy: Direct thrombin inhibitors suppress progression, dissemination and spontaneous metastasis in non-small cell lung cancer.
Zhao B, Wu M, Hu Z, Wang T, Yu J, Ma Y, Wang Q, Zhang Y, Chen D, Li T, Li Y, Yu M, Wang H, Mo W
British journal of pharmacology 2022 Nov;179(22):5056-5073
British journal of pharmacology 2022 Nov;179(22):5056-5073
The effects of scoparone on alcohol and high-fat diet-induced liver injury revealed by RNA sequencing.
Wei M, Li T, Cao H, He H, Yang C, Yin Y, Lu H, Novák P, Zhang K, Gao Y
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Nov;155:113770
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Nov;155:113770
The dipeptidyl peptidase-4 inhibitor linagliptin ameliorates LPS-induced acute lung injury by maintenance of pulmonary microvascular barrier via activating the Epac1/AKT pathway.
Zhang N, Tang S, Zhang J, Pei B, Pang T, Sun G
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Nov;155:113704
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Nov;155:113704
Lysophosphatidylcholine acyltransferase 1 alleviates silica-induced pulmonary fibrosis by modulating lipid metabolism.
Deng X, Hao C, Li Y, Guo Y, Si H, He J, Deng M, Niu Z, Wang C, Xu X, Dai K, Yao W
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Nov;155:113638
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Nov;155:113638
CHRNA5 Is Overexpressed in Patients with Psoriasis and Promotes Psoriasis-Like Inflammation in Mouse Models.
Wang J, Li X, Zhang P, Yang T, Liu N, Qin L, Ma G, Li X, Fan H, Huang S, Dang N
The Journal of investigative dermatology 2022 Nov;142(11):2978-2987.e6
The Journal of investigative dermatology 2022 Nov;142(11):2978-2987.e6
Molecular characterization of the evolutionary conserved signaling intermediate in Toll pathways (ECSIT) of soiny mullet (Liza haematocheila).
Qi Z, Pi X, Xu Y, Zhang Q, Wangkahart E, Meng F, Wang Z
Fish & shellfish immunology 2022 Nov;130:79-85
Fish & shellfish immunology 2022 Nov;130:79-85
The m(6)A methyltransferase METTL3 promotes trophoblast cell invasion by regulating MYLK expression.
Zhao J, Ding H, Ding J, Shi X, He Y, Zhu H, Yuan H, Zhang T, Zhang J
Placenta 2022 Nov;129:1-6
Placenta 2022 Nov;129:1-6
Diterpenoids from the whole plant of Euphorbia wallichii and their protective effects on H(2)O(2)-induced BV-2 microglial cells injury.
Wang Y, Zhu M, Liang J, Zhang N, Sun D, Li H, Chen L
Bioorganic chemistry 2022 Nov;128:106067
Bioorganic chemistry 2022 Nov;128:106067
HSP90B1 overexpression is associated with poor prognosis in tongue squamous cell carcinoma.
Chen YB, Feng YQ, Chen S
Journal of stomatology, oral and maxillofacial surgery 2022 Nov;123(6):e833-e838
Journal of stomatology, oral and maxillofacial surgery 2022 Nov;123(6):e833-e838
Pancreatic ductal adenocarcinoma cells regulated the gemcitabine-resistance function of CAFs by LINC00460.
Zhu XX, Li JH, Ni X, Wu X, Hou X, Li YX, Li SJ, Zhao W, Yin XY
Cancer science 2022 Nov;113(11):3735-3750
Cancer science 2022 Nov;113(11):3735-3750
Apelin-mediated deamidation of HMGA1 promotes tumorigenesis by enhancing SREBP1 activity and lipid synthesis.
Zhu Y, Yang Y, Bu H, Huang H, Chen H, Ran J, Qin L, Ni Y, Yao M, Song T, Li M, Yang Y, Guo T, Chao N, Liu Z, Li W, Zhang L
Cancer science 2022 Nov;113(11):3722-3734
Cancer science 2022 Nov;113(11):3722-3734
TaFDL2-1A confers drought stress tolerance by promoting ABA biosynthesis, ABA responses, and ROS scavenging in transgenic wheat.
Wang B, Li L, Liu M, Peng D, Wei A, Hou B, Lei Y, Li X
The Plant journal : for cell and molecular biology 2022 Nov;112(3):722-737
The Plant journal : for cell and molecular biology 2022 Nov;112(3):722-737
Phellopterin alleviates atopic dermatitis-like inflammation and suppresses IL-4-induced STAT3 activation in keratinocytes.
Chen X, Zhang Y, Pei J, Zeng X, Yang Y, Zhang Y, Li F, Deng Y
International immunopharmacology 2022 Nov;112:109270
International immunopharmacology 2022 Nov;112:109270
Myotubularin-Related Protein14 Prevents Neointima Formation and Vascular Smooth Muscle Cell Proliferation by Inhibiting Polo-Like Kinase1.
Kong LY, Liang C, Li PC, Zhang YW, Feng SD, Zhang DH, Yao R, Yang LL, Hao ZY, Zhang H, Tian XX, Guo CR, Du BB, Dong JZ, Zhang YZ
Journal of the American Heart Association 2022 Nov;11(21):e026174
Journal of the American Heart Association 2022 Nov;11(21):e026174
Identification of FDFT1 as a potential biomarker associated with ferroptosis in ccRCC.
Huang R, Zhang C, Wang X, Zou X, Xiang Z, Wang Z, Gui B, Lin T, Hu H
Cancer medicine 2022 Nov;11(21):3993-4004
Cancer medicine 2022 Nov;11(21):3993-4004
Ginsenoside Rg1 promotes remyelination and functional recovery in demyelinating disease by enhancing oligodendrocyte precursor cells-mediated myelin repair.
Liu L, Du X, Yang Q, Li M, Ran Q, Liu Q, Yang L, Sun L, Guo Y, Li Y, Chen Y, Zhu X, Li Q
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Nov;106:154309
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Nov;106:154309
Zika Virus Infection Downregulates Connexin 43, Disrupts the Cardiomyocyte Gap Junctions and Induces Heart Diseases in A129 Mice.
Li S, Armstrong N, Zhao H, Cruz-Cosme R, Yang H, Zhong C, Fu W, Wang W, Yang D, Xia N, Cheng T, Tang Q
Journal of virology 2022 Nov 9;96(21):e0137322
Journal of virology 2022 Nov 9;96(21):e0137322
Regulation of sleep quantity and intensity by long and short isoforms of SLEEPY kinase.
Xu J, Zhou R, Wang G, Guo Y, Gao X, Zhou S, Ma C, Chen L, Shi B, Wang H, Wang F, Liu Q
Sleep 2022 Nov 9;45(11)
Sleep 2022 Nov 9;45(11)
ATP Promotes Oral Squamous Cell Carcinoma Cell Invasion and Migration by Activating the PI3K/AKT Pathway via the P2Y2-Src-EGFR Axis.
Zhou Q, Liu S, Kou Y, Yang P, Liu H, Hasegawa T, Su R, Zhu G, Li M
ACS omega 2022 Nov 8;7(44):39760-39771
ACS omega 2022 Nov 8;7(44):39760-39771
Targeting the MITF/APAF-1 axis as salvage therapy for MAPK inhibitors in resistant melanoma.
Carotenuto P, Romano A, Barbato A, Quadrano P, Brillante S, Volpe M, Ferrante L, Tammaro R, Morleo M, De Cegli R, Iuliano A, Testa M, Andreone F, Ciliberto G, Clery E, Troncone G, Palma G, Arra C, Barbieri A, Capone M, Madonna G, Ascierto PA, Lanfrancone L, Indrieri A, Franco B
Cell reports 2022 Nov 8;41(6):111601
Cell reports 2022 Nov 8;41(6):111601
UNC13D inhibits STING signaling by attenuating its oligomerization on the endoplasmic reticulum.
Song P, Yang W, Lou KF, Dong H, Zhang H, Wang B, Chen D
EMBO reports 2022 Nov 7;23(11):e55099
EMBO reports 2022 Nov 7;23(11):e55099
The RNA polymerase II subunit Rpb9 activates ATG1 transcription and autophagy.
Huang T, Jiang G, Zhang Y, Lei Y, Liu S, Li H, Lu K
EMBO reports 2022 Nov 7;23(11):e54993
EMBO reports 2022 Nov 7;23(11):e54993
TRIM50 promotes NLRP3 inflammasome activation by directly inducing NLRP3 oligomerization.
Lin Y, Lv X, Sun C, Sun Y, Yang M, Ma D, Jing W, Zhao Y, Cheng Y, Xuan H, Han L
EMBO reports 2022 Nov 7;23(11):e54569
EMBO reports 2022 Nov 7;23(11):e54569
Mouse Bone Marrow Mesenchymal Stem Cells Inhibit Sepsis-Induced Lung Injury in Mice via Exosomal SAA1.
Lv Z, Duan S, Zhou M, Gu M, Li S, Wang Y, Xia Q, Xu D, Mao Y, Dong W, Jiang L
Molecular pharmaceutics 2022 Nov 7;19(11):4254-4263
Molecular pharmaceutics 2022 Nov 7;19(11):4254-4263
MiR-29a inhibits MPP + - Induced cell death and inflammation in Parkinson's disease model in vitro by potential targeting of MAVS.
Yang YL, Lin TK, Huang YH
European journal of pharmacology 2022 Nov 5;934:175302
European journal of pharmacology 2022 Nov 5;934:175302
RBM10 regulates alternative splicing of lncRNA Neat1 to inhibit the invasion and metastasis of NSCLC.
Cong S, Di X, Li R, Cao Y, Jin X, Tian C, Zhao M, Wang K
Cancer cell international 2022 Nov 5;22(1):338
Cancer cell international 2022 Nov 5;22(1):338
Irradiation-induced exosomal HMGB1 to confer radioresistance via the PI3K/AKT/FOXO3A signaling pathway in ESCC.
Du X, Zhang X, Dong J, Zou N, Guo D, Yao W, Wang X, Li S, Song C, Yan K, Shen W, Zhu S
Journal of translational medicine 2022 Nov 5;20(1):507
Journal of translational medicine 2022 Nov 5;20(1):507
Synthesis and Biological Evaluation of Cardiac Glycosides for Cancer Therapy by Targeting the DNA Damage Response.
Ainembabazi D, Geng X, Gavande NS, Turchi JJ, Zhang Y
ChemMedChem 2022 Nov 4;17(21):e202200415
ChemMedChem 2022 Nov 4;17(21):e202200415
Pterostilbene attenuates intrauterine growth retardation-induced colon inflammation in piglets by modulating endoplasmic reticulum stress and autophagy.
Chen Y, Zhang H, Li Y, Ji S, Jia P, Wang T
Journal of animal science and biotechnology 2022 Nov 4;13(1):125
Journal of animal science and biotechnology 2022 Nov 4;13(1):125
RNA-seq transcriptomic analysis of 4-octyl itaconate repressing myogenic differentiation.
Wang L, Chen Z, Feng Y, Wang R, Bai X, Liu W, Wang D
Archives of biochemistry and biophysics 2022 Nov 30;731:109420
Archives of biochemistry and biophysics 2022 Nov 30;731:109420
Sevoflurane-induced POCD-associated exosomes delivered miR-584-5p regulates the growth of human microglia HMC3 cells through targeting BDNF.
Zhao J, Zhang W, Wang S, Li Z, Huang Y, Li L
Aging 2022 Nov 30;14(24):9890-9907
Aging 2022 Nov 30;14(24):9890-9907
Metformin alleviates HFD-induced oxidative stress in hepatocyte via activating SIRT6/PGC-1α/ENDOG signaling.
Gao S, Yang Q, Liu Z, Kong W, Chen J, Li X, Peng Y, Bao M, Bian X, Zhang Y, Jiang Q, Li Z, Zhang Y, Yan F, Ye J
Clinical science (London, England : 1979) 2022 Nov 30;136(22):1711-1730
Clinical science (London, England : 1979) 2022 Nov 30;136(22):1711-1730
TGF-β2 Regulates Transcription of the K(+)/Cl(-) Cotransporter 2 (KCC2) in Immature Neurons and Its Phosphorylation at T1007 in Differentiated Neurons.
Rigkou A, Magyar A, Speer JM, Roussa E
Cells 2022 Nov 30;11(23)
Cells 2022 Nov 30;11(23)
Tim-4 reprograms cholesterol metabolism to suppress antiviral innate immunity by disturbing the Insig1-SCAP interaction in macrophages.
Wang Y, Wang Y, Ding L, Ren X, Wang B, Wang L, Zhao S, Yue X, Wu Z, Li C, Liang X, Ma C, Gao L
Cell reports 2022 Nov 29;41(9):111738
Cell reports 2022 Nov 29;41(9):111738
Social deficits via dysregulated Rac1-dependent excitability control of prefrontal cortical neurons and increased GABA/glutamate ratios.
Ma B, Shan X, Yu J, Zhu T, Li R, Lv H, Cheng H, Zhang T, Wang L, Wei F, Meng B, Yuan X, Mei B, Zhang XY, Li WG, Li F
Cell reports 2022 Nov 29;41(9):111722
Cell reports 2022 Nov 29;41(9):111722
Integrative Proteomics and Transcriptomics Profiles of the Oviduct Reveal the Prolificacy-Related Candidate Biomarkers of Goats (Capra hircus) in Estrous Periods.
Sun Z, Liu Y, He X, Di R, Wang X, Ren C, Zhang Z, Chu M
International journal of molecular sciences 2022 Nov 28;23(23)
International journal of molecular sciences 2022 Nov 28;23(23)
Regulation of ZO-1 on β-catenin mediates sulforaphane suppressed colorectal cancer stem cell properties in colorectal cancer.
Chen Y, Tang L, Ye X, Chen Y, Shan E, Han H, Zhong C
Food & function 2022 Nov 28;13(23):12363-12370
Food & function 2022 Nov 28;13(23):12363-12370
SRSF3 and HNRNPH1 Regulate Radiation-Induced Alternative Splicing of Protein Arginine Methyltransferase 5 in Hepatocellular Carcinoma.
Wen C, Tian Z, Li L, Chen T, Chen H, Dai J, Liang Z, Ma S, Liu X
International journal of molecular sciences 2022 Nov 27;23(23)
International journal of molecular sciences 2022 Nov 27;23(23)
The proatherosclerotic function of BCAT1 in atherosclerosis development of aged-apolipoprotein E-deficient mice.
Tan L, Lu J, Zhang C, Meng L, Zhu Q
Biochemical and biophysical research communications 2022 Nov 26;631:93-101
Biochemical and biophysical research communications 2022 Nov 26;631:93-101
Discovery of a Novel Bloom's Syndrome Protein (BLM) Inhibitor Suppressing Growth and Metastasis of Prostate Cancer.
Ma XY, Xu HQ, Zhao JF, Ruan Y, Chen B
International journal of molecular sciences 2022 Nov 26;23(23)
International journal of molecular sciences 2022 Nov 26;23(23)
Expression of expanded GGC repeats within NOTCH2NLC causes behavioral deficits and neurodegeneration in a mouse model of neuronal intranuclear inclusion disease.
Liu Q, Zhang K, Kang Y, Li Y, Deng P, Li Y, Tian Y, Sun Q, Tang Y, Xu K, Zhou Y, Wang JL, Guo J, Li JD, Xia K, Meng Q, Allen EG, Wen Z, Li Z, Jiang H, Shen L, Duan R, Yao B, Tang B, Jin P, Pan Y
Science advances 2022 Nov 25;8(47):eadd6391
Science advances 2022 Nov 25;8(47):eadd6391
An insecticide target in mechanoreceptor neurons.
Qiao X, Zhang X, Zhou Z, Guo L, Wu W, Ma S, Zhang X, Montell C, Huang J
Science advances 2022 Nov 25;8(47):eabq3132
Science advances 2022 Nov 25;8(47):eabq3132
Pt(IV) Prodrug as a Potential Antitumor Agent with APE1 Inhibitory Activity.
Yuan Y, Fu D, Xu Y, Wang X, Deng X, Zhou S, Du F, Cui X, Deng Y, Tang Z
Journal of medicinal chemistry 2022 Nov 24;65(22):15344-15357
Journal of medicinal chemistry 2022 Nov 24;65(22):15344-15357
Blockade of Kv1.3 Potassium Channel Inhibits Microglia-Mediated Neuroinflammation in Epilepsy.
Zhang X, Liang P, Zhang Y, Wu Y, Song Y, Wang X, Chen T, Peng B, Liu W, Yin J, Han S, He X
International journal of molecular sciences 2022 Nov 24;23(23)
International journal of molecular sciences 2022 Nov 24;23(23)
New Baitouweng decoction combined with fecal microbiota transplantation alleviates DSS-induced colitis in rats by regulating gut microbiota metabolic homeostasis and the STAT3/NF-κB signaling pathway.
Gu X, Miao Z, Wang Y, Yang Y, Yang T, Xu Y
BMC complementary medicine and therapies 2022 Nov 24;22(1):307
BMC complementary medicine and therapies 2022 Nov 24;22(1):307
Integrated metabolomics, network pharmacology and biological verification to reveal the mechanisms of Nauclea officinalis treatment of LPS-induced acute lung injury.
Xu H, Xu S, Li L, Wu Y, Mai S, Xie Y, Tan Y, Li A, Xue F, He X, Li Y
Chinese medicine 2022 Nov 24;17(1):131
Chinese medicine 2022 Nov 24;17(1):131
Diosgenin Ameliorated Type II Diabetes-Associated Nonalcoholic Fatty Liver Disease through Inhibiting De Novo Lipogenesis and Improving Fatty Acid Oxidation and Mitochondrial Function in Rats.
Zhong Y, Li Z, Jin R, Yao Y, He S, Lei M, Wang X, Shi C, Gao L, Peng X
Nutrients 2022 Nov 24;14(23)
Nutrients 2022 Nov 24;14(23)
Aberrant amino acid metabolism promotes neurovascular reactivity in rosacea.
Liu T, Xiao W, Chen M, Mao R, San X, Peng Q, Zhao Z, Wang Q, Xie H, Deng Z, Li J
JCI insight 2022 Nov 22;7(22)
JCI insight 2022 Nov 22;7(22)
circPRKAA1 activates a Ku80/Ku70/SREBP-1 axis driving de novo fatty acid synthesis in cancer cells.
Li Q, Yao H, Wang Y, Wu Y, Thorne RF, Zhu Y, Wu M, Liu L
Cell reports 2022 Nov 22;41(8):111707
Cell reports 2022 Nov 22;41(8):111707
Dynamic quality control machinery that operates across compartmental borders mediates the degradation of mammalian nuclear membrane proteins.
Tsai PL, Cameron CJF, Forni MF, Wasko RR, Naughton BS, Horsley V, Gerstein MB, Schlieker C
Cell reports 2022 Nov 22;41(8):111675
Cell reports 2022 Nov 22;41(8):111675
Neutrophil Nanovesicle Protects against Experimental Autoimmune Encephalomyelitis through Enhancing Myelin Clearance by Microglia.
Shen S, Cheng X, Zhou L, Zhao Y, Wang H, Zhang J, Sun X, Wang Y, Shu Y, Xu Y, Tao Y, Li M, Lu Z, Cai W, Nie G, Qiu W
ACS nano 2022 Nov 22;16(11):18886-18897
ACS nano 2022 Nov 22;16(11):18886-18897
IL-37 alleviates Coxsackievirus B3-induced viral myocarditis via inhibiting NLRP3 inflammasome-mediated pyroptosis.
Sun L, Yuan H, Zhao G
Scientific reports 2022 Nov 22;12(1):20077
Scientific reports 2022 Nov 22;12(1):20077
Naringenin Promotes Myotube Formation and Maturation for Cultured Meat Production.
Yan Q, Fei Z, Li M, Zhou J, Du G, Guan X
Foods (Basel, Switzerland) 2022 Nov 22;11(23)
Foods (Basel, Switzerland) 2022 Nov 22;11(23)
Apigenin Ameliorates Hyperuricemia and Renal Injury through Regulation of Uric Acid Metabolism and JAK2/STAT3 Signaling Pathway.
Liu T, Gao H, Zhang Y, Wang S, Lu M, Dai X, Liu Y, Shi H, Xu T, Yin J, Gao S, Wang L, Zhang D
Pharmaceuticals (Basel, Switzerland) 2022 Nov 21;15(11)
Pharmaceuticals (Basel, Switzerland) 2022 Nov 21;15(11)
RSAD2 Is an Effective Target for High-Yield Vaccine Production in MDCK Cells.
Qiao Z, Liao Y, Pei M, Qiu Z, Liu Z, Jin D, Zhang J, Ma Z, Yang X
Viruses 2022 Nov 21;14(11)
Viruses 2022 Nov 21;14(11)
NMN ameliorated radiation induced damage in NRF2-deficient cell and mice via regulating SIRT6 and SIRT7.
Zhao X, Zhang M, Wang J, Ji K, Wang Y, Sun X, Xu C, Wang Q, He N, Song H, Du L, Wang F, Huang H, Liu Y, Liu Q
Free radical biology & medicine 2022 Nov 20;193(Pt 1):342-353
Free radical biology & medicine 2022 Nov 20;193(Pt 1):342-353
Cell-cell contact-driven EphB1 cis- and trans- signalings regulate cancer stem cells enrichment after chemotherapy.
Wang L, Peng Q, Xie Y, Yin N, Xu J, Chen A, Yi J, Shi W, Tang J, Xiang J
Cell death & disease 2022 Nov 19;13(11):980
Cell death & disease 2022 Nov 19;13(11):980
BRAF activation by metabolic stress promotes glycolysis sensitizing NRAS(Q61)-mutated melanomas to targeted therapy.
McGrail K, Granado-Martínez P, Esteve-Puig R, García-Ortega S, Ding Y, Sánchez-Redondo S, Ferrer B, Hernandez-Losa J, Canals F, Manzano A, Navarro-Sabaté A, Bartrons R, Yanes O, Pérez-Alea M, Muñoz-Couselo E, Garcia-Patos V, Recio JA
Nature communications 2022 Nov 19;13(1):7113
Nature communications 2022 Nov 19;13(1):7113
Swine acute diarrhea syndrome coronavirus induces autophagy to promote its replication via the Akt/mTOR pathway.
Zeng S, Zhao Y, Peng O, Xia Y, Xu Q, Li H, Xue C, Cao Y, Zhang H
iScience 2022 Nov 18;25(11):105394
iScience 2022 Nov 18;25(11):105394
Cancer cell intrinsic TIM-3 induces glioblastoma progression.
Guo Q, Shen S, Guan G, Zhu C, Zou C, Cao J, Cheng W, Xu X, Yu J, Lin Z, Wang G, Chen L, Cheng P, Wu A
iScience 2022 Nov 18;25(11):105329
iScience 2022 Nov 18;25(11):105329
Identification of purine biosynthesis as an NADH-sensing pathway to mediate energy stress.
Yang R, Yang C, Ma L, Zhao Y, Guo Z, Niu J, Chu Q, Ma Y, Li B
Nature communications 2022 Nov 17;13(1):7031
Nature communications 2022 Nov 17;13(1):7031
m(6)A modification of circSPECC1 suppresses RPE oxidative damage and maintains retinal homeostasis.
Chen X, Wang Y, Wang JN, Cao QC, Sun RX, Zhu HJ, Zhang YR, Ji JD, Liu QH
Cell reports 2022 Nov 15;41(7):111671
Cell reports 2022 Nov 15;41(7):111671
N6-methyladenosine modification on Hmbox1 is related to telomere dysfunction in DEHP-induced male reproductive injury.
Zhu X, Fu H, Sun J, Di Q, Xu Q
Life sciences 2022 Nov 15;309:121005
Life sciences 2022 Nov 15;309:121005
Sophocarpine Alleviates Isoproterenol-Induced Kidney Injury by Suppressing Inflammation, Apoptosis, Oxidative Stress and Fibrosis.
Zhou W, Fu Y, Xu JS
Molecules (Basel, Switzerland) 2022 Nov 15;27(22)
Molecules (Basel, Switzerland) 2022 Nov 15;27(22)
Methyl Gallate Alleviates Acute Ulcerative Colitis by Modulating Gut Microbiota and Inhibiting TLR4/NF-κB Pathway.
Zhou P, Lai J, Li Y, Deng J, Zhao C, Huang Q, Yang F, Yang S, Wu Y, Tang X, Huang F, Wang L, Huang X, Zou W, Wu J
International journal of molecular sciences 2022 Nov 14;23(22)
International journal of molecular sciences 2022 Nov 14;23(22)
A SERPINE1-Based Immune Gene Signature Predicts Prognosis and Immunotherapy Response in Gastric Cancer.
Xu X, Zhang L, Qian Y, Fang Q, Xiao Y, Chen G, Cai G, Abula A, Wang Z, Zhai E, Chen J, Cai S, Wu H
Pharmaceuticals (Basel, Switzerland) 2022 Nov 14;15(11)
Pharmaceuticals (Basel, Switzerland) 2022 Nov 14;15(11)
Dissecting Heterogeneity Reveals a Unique BAMBI(high) MFGE8(high) Subpopulation of Human UC-MSCs.
Chen H, Wen X, Liu S, Sun T, Song H, Wang F, Xu J, Zhang Y, Zhao Y, Yu J, Sun L
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2022 Nov 14;10(1):e2202510
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2022 Nov 14;10(1):e2202510
A novel Granzymes and miRNA nanocapsules co-delivery system for tumor suppression.
Shi Z, Zhao M, Lin T, Chen J, Qian X
Biomedical physics & engineering express 2022 Nov 11;8(6)
Biomedical physics & engineering express 2022 Nov 11;8(6)
METTL3-mediated m6A modification stabilizes TERRA and maintains telomere stability.
Chen L, Zhang C, Ma W, Huang J, Zhao Y, Liu H
Nucleic acids research 2022 Nov 11;50(20):11619-11634
Nucleic acids research 2022 Nov 11;50(20):11619-11634
Dihydrotanshinone I Inhibits the Proliferation and Growth of Oxaliplatin-Resistant Human HCT116 Colorectal Cancer Cells.
Wang M, Xiang Y, Wang R, Zhang L, Zhang H, Chen H, Luan X, Chen L
Molecules (Basel, Switzerland) 2022 Nov 11;27(22)
Molecules (Basel, Switzerland) 2022 Nov 11;27(22)
Deubiquitinase USP35 stabilizes BRPF1 to activate mevalonate (MVA) metabolism during prostate tumorigenesis.
Lin G, Huang T, Zhang X, Wang G
Cell death discovery 2022 Nov 10;8(1):453
Cell death discovery 2022 Nov 10;8(1):453
Systematic characterization of cancer transcriptome at transcript resolution.
Hu W, Wu Y, Shi Q, Wu J, Kong D, Wu X, He X, Liu T, Li S
Nature communications 2022 Nov 10;13(1):6803
Nature communications 2022 Nov 10;13(1):6803
Obese Skeletal Muscle-Expressed Interferon Regulatory Factor 4 Transcriptionally Regulates Mitochondrial Branched-Chain Aminotransferase Reprogramming Metabolome.
Yao T, Yan H, Zhu X, Zhang Q, Kong X, Guo S, Feng Y, Wang H, Hua Y, Zhang J, Mittelman SD, Tontonoz P, Zhou Z, Liu T, Kong X
Diabetes 2022 Nov 1;71(11):2256-2271
Diabetes 2022 Nov 1;71(11):2256-2271
Exosome-derived FGD5-AS1 promotes tumor-associated macrophage M2 polarization-mediated pancreatic cancer cell proliferation and metastasis.
He Z, Wang J, Zhu C, Xu J, Chen P, Jiang X, Chen Y, Jiang J, Sun C
Cancer letters 2022 Nov 1;548:215751
Cancer letters 2022 Nov 1;548:215751
Acute depletion of human core nucleoporin reveals direct roles in transcription control but dispensability for 3D genome organization.
Zhu X, Qi C, Wang R, Lee JH, Shao J, Bei L, Xiong F, Nguyen PT, Li G, Krakowiak J, Koh SP, Simon LM, Han L, Moore TI, Li W
Cell reports 2022 Nov 1;41(5):111576
Cell reports 2022 Nov 1;41(5):111576
Effects of apolipoprotein E on regulating insulin sensitivity via regulating insulin receptor signalosome in caveolae.
Liu M, Chen MY, An L, Ma SQ, Mei J, Huang WH, Zhang W
Life sciences 2022 Nov 1;308:120929
Life sciences 2022 Nov 1;308:120929
Bufalin Inhibits Tumorigenesis, Stemness, and Epithelial-Mesenchymal Transition in Colorectal Cancer through a C-Kit/Slug Signaling Axis.
Ding L, Yang Y, Lu Q, Qu D, Chandrakesan P, Feng H, Chen H, Chen X, Liao Z, Du J, Cao Z, Weygant N
International journal of molecular sciences 2022 Nov 1;23(21)
International journal of molecular sciences 2022 Nov 1;23(21)
Optimized Transcriptional Signature for Evaluation of MEK/ERK Pathway Baseline Activity and Long-Term Modulations in Ovarian Cancer.
Chesnokov MS, Yadav A, Chefetz I
International journal of molecular sciences 2022 Nov 1;23(21)
International journal of molecular sciences 2022 Nov 1;23(21)
Potential mechanisms underlying the promoting effects of 3D collagen scaffold culture on stemness and drug resistance of glioma cells.
Jia W, Zhu H, Zhao M, Zhou Q, Yin W, Liu W, Wang L, Xiao Z, Jiang X, Dai J, Ren C
Biochimica et biophysica acta. Molecular basis of disease 2022 Nov 1;1868(11):166522
Biochimica et biophysica acta. Molecular basis of disease 2022 Nov 1;1868(11):166522
Effects of the m6Am methyltransferase PCIF1 on cell proliferation and survival in gliomas.
Gao S, Zhou J, Hu Z, Zhang S, Wu Y, Musunuru PP, Zhang T, Yang L, Luo X, Bai J, Meng Q, Yu R
Biochimica et biophysica acta. Molecular basis of disease 2022 Nov 1;1868(11):166498
Biochimica et biophysica acta. Molecular basis of disease 2022 Nov 1;1868(11):166498
Activation of the Aryl Hydrocarbon Receptor Ameliorates Acute Rejection of Rat Liver Transplantation by Regulating Treg Proliferation and PD-1 Expression.
Cao W, Lu J, Li L, Qiu C, Qin X, Wang T, Li S, Zhang J, Xu J
Transplantation 2022 Nov 1;106(11):2172-2181
Transplantation 2022 Nov 1;106(11):2172-2181
Salidroside protects against osteoporosis in ovariectomized rats by inhibiting oxidative stress and promoting osteogenesis via Nrf2 activation.
Wang YF, Chang YY, Zhang XM, Gao MT, Zhang QL, Li X, Zhang L, Yao WF
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 May;99:154020
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 May;99:154020
MiR-1298-5p level downregulation induced by Helicobacter pylori infection inhibits autophagy and promotes gastric cancer development by targeting MAP2K6.
Li X, Zhu M, Zhao G, Zhou A, Min L, Liu S, Zhang N, Zhu S, Guo Q, Zhang S, Li P
Cellular signalling 2022 May;93:110286
Cellular signalling 2022 May;93:110286
Ubiquitin ligase DTX3 empowers mutant p53 to promote ovarian cancer development.
Wang S, Hao Q, Li J, Chen Y, Lu H, Wu X, Zhou X
Genes & diseases 2022 May;9(3):705-716
Genes & diseases 2022 May;9(3):705-716
Collagen peptides from Acaudina molpadioides prevent CCl(4) -induced liver injury via Keap1/Nrf2-ARE, PI3K/AKT, and MAPKs pathways.
Li J, Li Y, Lin S, Zhao W, Chen Y, Jin H
Journal of food science 2022 May;87(5):2185-2196
Journal of food science 2022 May;87(5):2185-2196
Sinapic acid inhibits pancreatic cancer proliferation, migration, and invasion via downregulation of the AKT/Gsk-3β signal pathway.
Huang Z, Chen H, Tan P, Huang M, Shi H, Sun B, Cheng Y, Li T, Mou Z, Li Q, Fu W
Drug development research 2022 May;83(3):721-734
Drug development research 2022 May;83(3):721-734
Renal tubule ectopic lipid deposition in diabetic kidney disease rat model and in vitro mechanism of leptin intervention.
Liu S, Da J, Yu J, Dong R, Yuan J, Yu F, Zha Y
Journal of physiology and biochemistry 2022 May;78(2):389-399
Journal of physiology and biochemistry 2022 May;78(2):389-399
Hippocampal Activated Microglia May Contribute to Blood-Brain Barrier Impairment and Cognitive Dysfunction in Post-Traumatic Stress Disorder-Like Rats.
Ni K, Zhu J, Xu X, Liu Y, Yang S, Huang Y, Xu R, Jiang L, Zhang J, Zhang W, Ma Z
Journal of molecular neuroscience : MN 2022 May;72(5):975-982
Journal of molecular neuroscience : MN 2022 May;72(5):975-982
Macrophage-targeted delivery of siRNA to silence Mecp2 gene expression attenuates pulmonary fibrosis.
Mou Y, Wu GR, Wang Q, Pan T, Zhang L, Xu Y, Xiong W, Zhou Q, Wang Y
Bioengineering & translational medicine 2022 May;7(2):e10280
Bioengineering & translational medicine 2022 May;7(2):e10280
Novel lissencephaly-associated DCX variants in the C-terminal DCX domain affect microtubule binding and dynamics.
Lin JR, Cheng JF, Liu YT, Hsu TR, Lin KM, Chen C, Lin CL, Tsai MH, Tsai JW
Epilepsia 2022 May;63(5):1253-1265
Epilepsia 2022 May;63(5):1253-1265
Adrenomedullin ameliorates palmitic acid-induced insulin resistance through PI3K/Akt pathway in adipocytes.
Dai HB, Wang HY, Wang FZ, Qian P, Gao Q, Zhou H, Zhou YB
Acta diabetologica 2022 May;59(5):661-673
Acta diabetologica 2022 May;59(5):661-673
Quercetin Alleviates Demyelination Through Regulating Microglial Phenotype Transformation to Mitigate Neuropsychiatric Symptoms in Mice with Vascular Dementia.
Tan Z, Yang G, Qiu J, Yan W, Liu Y, Ma Z, Li J, Liu J, Shan N
Molecular neurobiology 2022 May;59(5):3140-3158
Molecular neurobiology 2022 May;59(5):3140-3158
The interaction of O-GlcNAc-modified NLRX1 and IKK-α modulates IL-1β expression in M1 macrophages.
Chen L, Li Y, Zeng S, Duan S, Huang Z, Liang Y
In vitro cellular & developmental biology. Animal 2022 May;58(5):408-418
In vitro cellular & developmental biology. Animal 2022 May;58(5):408-418
Antioxidant and Immunomodulatory Properties of Partially purified Exopolysaccharide from Lactobacillus Casei Isolated from Chinese Northeast Sauerkraut.
Xu X, Qiao Y, Peng Q, Shi B, Dia VP
Immunological investigations 2022 May;51(4):748-765
Immunological investigations 2022 May;51(4):748-765
Long Noncoding RNAs Hepatocyte Nuclear Factor 4A Antisense RNA 1 and Hepatocyte Nuclear Factor 1A Antisense RNA 1 Are Involved in Ritonavir-Induced Cytotoxicity in Hepatoma Cells.
Wang X, Yu Y, Wang P, Yang K, Wang Y, Yan L, Zhong XB, Zhang L
Drug metabolism and disposition: the biological fate of chemicals 2022 May;50(5):704-715
Drug metabolism and disposition: the biological fate of chemicals 2022 May;50(5):704-715
CCL2 activates AKT signaling to promote glycolysis and chemoresistance in glioma cells.
Qian Y, Ding P, Xu J, Nie X, Lu B
Cell biology international 2022 May;46(5):819-828
Cell biology international 2022 May;46(5):819-828
PFOS facilitates liver inflammation and steatosis: An involvement of NLRP3 inflammasome-mediated hepatocyte pyroptosis.
Qin Y, Gu T, Ling J, Luo J, Zhao J, Hu B, Hua L, Wan C, Jiang S
Journal of applied toxicology : JAT 2022 May;42(5):806-817
Journal of applied toxicology : JAT 2022 May;42(5):806-817
CRL2(KLHDC3) mediates p14ARF N-terminal ubiquitylation degradation to promote non-small cell lung carcinoma progression.
Liu Y, Luo Y, Yan S, Lian YF, Wu S, Xu M, Feng L, Zhang X, Li R, Zhang X, Feng QS, Zeng YX, Zhang H
Oncogene 2022 May;41(22):3104-3117
Oncogene 2022 May;41(22):3104-3117
RNA N6-methyladenosine demethylase FTO promotes pancreatic cancer progression by inducing the autocrine activity of PDGFC in an m(6)A-YTHDF2-dependent manner.
Tan Z, Shi S, Xu J, Liu X, Lei Y, Zhang B, Hua J, Meng Q, Wang W, Yu X, Liang C
Oncogene 2022 May;41(20):2860-2872
Oncogene 2022 May;41(20):2860-2872
microRNA-1321 and microRNA-7515 contribute to the progression of non-small cell lung cancer by targeting CDC20.
Hu H, Tou FF, Mao WM, Xu YL, Jin H, Kuang YK, Han CB, Guo CY
The Kaohsiung journal of medical sciences 2022 May;38(5):425-436
The Kaohsiung journal of medical sciences 2022 May;38(5):425-436
Selenium protects against cadmium-induced cardiac injury by attenuating programmed cell death via PI3K/AKT/PTEN signaling.
Feng J, Yang F, Wu H, Xing C, Xue H, Zhang L, Zhang C, Hu G, Cao H
Environmental toxicology 2022 May;37(5):1185-1197
Environmental toxicology 2022 May;37(5):1185-1197
Blocking PARP activity with the inhibitor veliparib enhances radiotherapy sensitivity in endometrial carcinoma.
Wang J, Xing W, Lin Y, Uskenbayeva N, Yan H, Xu Y, Fang L
Journal of clinical laboratory analysis 2022 May;36(5):e24435
Journal of clinical laboratory analysis 2022 May;36(5):e24435
Nrf2 improves hippocampal synaptic plasticity, learning and memory through the circ-Vps41/miR-26a-5p/CaMKIV regulatory network.
Zhang R, Gao Y, Li Y, Geng D, Liang Y, He Q, Wang L, Cui H
Experimental neurology 2022 May;351:113998
Experimental neurology 2022 May;351:113998
Correlation of vascular change with TRPV1, TRPV4, and TRPA1 in a rat model of inferior gluteal artery perforator flap.
Li X, Li X, Chen Y, Wang Y, Li X, Hao A, Hu Y, Li X
Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society 2022 May;30(3):365-375
Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society 2022 May;30(3):365-375
Capsaicin inhibits intestinal Cl(-) secretion and promotes Na(+) absorption by blocking TRPV4 channels in healthy and colitic mice.
Wan H, Chen XY, Zhang F, Chen J, Chu F, Sellers ZM, Xu F, Dong H
The Journal of biological chemistry 2022 May;298(5):101847
The Journal of biological chemistry 2022 May;298(5):101847
An miRNA derived from amelogenin exon4 regulates expression of transcription factor Runx2 by directly targeting upstream activators Nfia and Prkch.
Shemirani R, Lin G, Abduweli Uyghurturk D, Le M, Nakano Y
The Journal of biological chemistry 2022 May;298(5):101807
The Journal of biological chemistry 2022 May;298(5):101807
Dibutyltin dichloride exposure affects mouse oocyte quality by inducing spindle defects and mitochondria dysfunction.
Lu Y, Tang H, Wang X, Xu J, Sun F
Chemosphere 2022 May;295:133959
Chemosphere 2022 May;295:133959
The application of CRISPR/Cas9 system in cervical carcinogenesis.
Gao C, Wu P, Yu L, Liu L, Liu H, Tan X, Wang L, Huang X, Wang H
Cancer gene therapy 2022 May;29(5):466-474
Cancer gene therapy 2022 May;29(5):466-474
Involvement of calcium homeostasis and unfolded protein response in autophagy co-induced by molybdenum and cadmium in duck (Anas platyrhyncha) brain.
Lin T, Nie G, Hu R, Luo J, Xing C, Hu G, Zhang C
Environmental science and pollution research international 2022 May;29(25):38303-38314
Environmental science and pollution research international 2022 May;29(25):38303-38314
PM(2.5) causes vascular hyperreactivity through the upregulation of the thromboxane A(2) receptor and activation of MAPK pathways.
Wang R, Wang J, Sun J, Yang K, Wang N, Qin B
Environmental science and pollution research international 2022 May;29(22):33095-33105
Environmental science and pollution research international 2022 May;29(22):33095-33105
Naturally occurring UBIAD1 mutations differentially affect menaquinone biosynthesis and vitamin K-dependent carboxylation.
Chen X, Furukawa N, Jin DY, Liu Y, Stafford DW, Williams CM, Suhara Y, Tie JK
The FEBS journal 2022 May;289(9):2613-2627
The FEBS journal 2022 May;289(9):2613-2627
Type IIB PKA is highly expressed in β cells and controls cell proliferation via regulating Cyclin D1 expression.
Jiang Y, Zhu L, Wu D, Ni Y, Huang C, Ye H, Yang Y, Liu R, Li Y
The FEBS journal 2022 May;289(10):2865-2876
The FEBS journal 2022 May;289(10):2865-2876
Evaluation of the TRIP13 level in breast cancer and insights into potential molecular pathways.
Lan J, Huang J, Tao X, Gao Y, Zhang L, Huang W, Luo J, Liu C, Deng Y, Liu L, Liu X
Journal of cellular and molecular medicine 2022 May;26(9):2673-2685
Journal of cellular and molecular medicine 2022 May;26(9):2673-2685
Novel chloroquine derivative suppresses melanoma cell growth by DNA damage through increasing ROS levels.
Li J, Long J, Zhang J, Liu N, Yan B, Tang L, Chen X, Peng C
Journal of cellular and molecular medicine 2022 May;26(9):2579-2593
Journal of cellular and molecular medicine 2022 May;26(9):2579-2593
Leukemia inhibitory factor is dysregulated in ankylosing spondylitis and contributes to bone formation.
Kong W, Tang Y, Tang K, Yan Z, Liu T, Tao Q, Wang J, Liu J, Yan X
International journal of rheumatic diseases 2022 May;25(5):592-600
International journal of rheumatic diseases 2022 May;25(5):592-600
LncRNA SOX2OT facilitates LPS-induced inflammatory injury by regulating intercellular adhesion molecule 1 (ICAM1) via sponging miR-215-5p.
Zhu W, Peng F, Cui X, Li J, Sun C
Clinical immunology (Orlando, Fla.) 2022 May;238:109006
Clinical immunology (Orlando, Fla.) 2022 May;238:109006
Radix ranunculus temate saponins sensitizes ovarian cancer to Taxol via upregulation of miR-let-7b.
You K, Liu Y, Chen L, Ye H, Lin W
Experimental and therapeutic medicine 2022 May;23(5):315
Experimental and therapeutic medicine 2022 May;23(5):315
A synapsin Ⅰ cleavage fragment contributes to synaptic dysfunction in Alzheimer's disease.
Meng L, Zou L, Xiong M, Chen J, Zhang X, Yu T, Li Y, Liu C, Chen G, Wang Z, Ye K, Zhang Z
Aging cell 2022 May;21(5):e13619
Aging cell 2022 May;21(5):e13619
Human and mouse PAR4 are functionally distinct receptors: Studies in novel humanized mice.
Renna SA, Michael JV, Kong X, Ma L, Ma P, Nieman MT, Edelstein LC, McKenzie SE
Journal of thrombosis and haemostasis : JTH 2022 May;20(5):1236-1247
Journal of thrombosis and haemostasis : JTH 2022 May;20(5):1236-1247
In vivo cyclic induction of the FOXM1 transcription factor delays natural and progeroid aging phenotypes and extends healthspan.
Ribeiro R, Macedo JC, Costa M, Ustiyan V, Shindyapina AV, Tyshkovskiy A, Gomes RN, Castro JP, Kalin TV, Vasques-Nóvoa F, Nascimento DS, Dmitriev SE, Gladyshev VN, Kalinichenko VV, Logarinho E
Nature aging 2022 May;2(5):397-411
Nature aging 2022 May;2(5):397-411
Metformin increases the radiosensitivity of non-small cell lung cancer cells by destabilizing NRF2.
Sun X, Dong M, Gao Y, Wang Y, Du L, Liu Y, Wang Q, Ji K, He N, Wang J, Zhang M, Gu Y, Song H, Zhai H, Feng L, Xu C, Liu Q
Biochemical pharmacology 2022 May;199:114981
Biochemical pharmacology 2022 May;199:114981
Exosomal MMP-1 transfers metastasis potential in triple-negative breast cancer through PAR1-mediated EMT.
Zhu Y, Tao Z, Chen Y, Lin S, Zhu M, Ji W, Liu X, Li T, Hu X
Breast cancer research and treatment 2022 May;193(1):65-81
Breast cancer research and treatment 2022 May;193(1):65-81
Dihydroflavonoids as Bioactive Components of Penthorum chinense, a Miao Ethnomedicine, against NAFLD through Bile Acid Metabolism Pathway.
Li X, Li Y, Zhao W, Yu L, Hu X, Zhao Y, Guo Q, Wang X, Wu X
Chemistry & biodiversity 2022 May;19(5):e202200146
Chemistry & biodiversity 2022 May;19(5):e202200146
Comparative subcellular localization of NRF2 and KEAP1 during the hepatocellular carcinoma development in vivo.
Guerrero-Escalera D, Alarcón-Sánchez BR, Arellanes-Robledo J, Cruz-Rangel A, Del Pozo-Yauner L, Chagoya de Sánchez V, Resendis-Antonio O, Villa-Treviño S, Torres-Mena JE, Pérez-Carreón JI
Biochimica et biophysica acta. Molecular cell research 2022 May;1869(5):119222
Biochimica et biophysica acta. Molecular cell research 2022 May;1869(5):119222
Increased alveolar epithelial TRAF6 via autophagy-dependent TRIM37 degradation mediates particulate matter-induced lung metastasis.
Liu J, Li S, Fei X, Nan X, Shen Y, Xiu H, Cormier SA, Lu C, Guo C, Wang S, Cai Z, Wang P
Autophagy 2022 May;18(5):971-989
Autophagy 2022 May;18(5):971-989
Pubertal changes in the pituitary and adrenal glands of male and female rats: Relevance to stress reactivity.
Kann RB, Romeo RD
Neurobiology of stress 2022 May;18:100457
Neurobiology of stress 2022 May;18:100457
Intrinsic features of Zika Virus non-structural proteins NS2A and NS4A in the regulation of viral replication.
Yu Y, Gao C, Wen C, Zou P, Qi X, Cardona CJ, Xing Z
PLoS neglected tropical diseases 2022 May;16(5):e0010366
PLoS neglected tropical diseases 2022 May;16(5):e0010366
Nanoformulation of a carbon monoxide releasing molecule protects against cyclosporin A-induced nephrotoxicity and renal fibrosis via the suppression of the NLRP3 inflammasome mediated TGF-β/Smad pathway.
Xia Z, Zhang C, Guo C, Song B, Hu W, Cui Y, Xue Y, Xia M, Xu D, Zhang S, Fang J
Acta biomaterialia 2022 May;144:42-53
Acta biomaterialia 2022 May;144:42-53
A novel ribosomal protein S6 kinase 2 inhibitor attenuates the malignant phenotype of cutaneous malignant melanoma cells by inducing cell cycle arrest and apoptosis.
Li Y, Yu P, Long J, Tang L, Zhang X, Zhou Z, Cao D, Su J, Chen X, Peng C
Bioengineered 2022 May;13(5):13555-13570
Bioengineered 2022 May;13(5):13555-13570
Sex-determining Region Y-box transcription factor 13 promotes breast cancer cell proliferation and glycolysis by activating the tripartite motif containing 11-mediated Wnt/β-catenin signaling pathway.
Jin X, Shao X, Pang W, Wang Z, Huang J
Bioengineered 2022 May;13(5):13033-13044
Bioengineered 2022 May;13(5):13033-13044
MicroRNA-744-5p suppresses tumorigenesis and metastasis of osteosarcoma through the p38 mitogen-activated protein kinases pathway by targeting transforming growth factor-beta 1.
Liang H, Li L, Zhu S, Tan J, Yang B, Wang X, Wu G, Xie C, Li L, Liu Z, Li Y, Song H, Chen G, Lin L
Bioengineered 2022 May;13(5):12309-12325
Bioengineered 2022 May;13(5):12309-12325
Long non-coding RNA lincRNA-erythroid prosurvival (EPS) alleviates cerebral ischemia/reperfusion injury by maintaining high-temperature requirement protein A1 (Htra1) stability through recruiting heterogeneous nuclear ribonucleoprotein L (HNRNPL).
Guo H, Guo X, Jiang S
Bioengineered 2022 May;13(5):12248-12260
Bioengineered 2022 May;13(5):12248-12260
Characterization of the Eimeria tenella rhoptry protein with a nuclear localization sequence (EtROP30).
Bingxiang W, Ningning Z, Yakun W, Lingyu S, Hongmei L, Zhang X, Zhao X
Parasitology research 2022 May;121(5):1507-1516
Parasitology research 2022 May;121(5):1507-1516
Genome-wide gain-of-function screening identifies EZH2 mediating resistance to PI3Kα inhibitors in oesophageal squamous cell carcinoma.
Xing H, Gao M, Wang Y, Zhang X, Shi J, Wang X, Liu X, Ma Q, Kong X, Yang C, Ding J, Meng L
Clinical and translational medicine 2022 May;12(5):e835
Clinical and translational medicine 2022 May;12(5):e835
MicroRNA-34c-5p provokes isoprenaline-induced cardiac hypertrophy by modulating autophagy via targeting ATG4B.
Zhang Y, Ding Y, Li M, Yuan J, Yu Y, Bi X, Hong H, Ye J, Liu P
Acta pharmaceutica Sinica. B 2022 May;12(5):2374-2390
Acta pharmaceutica Sinica. B 2022 May;12(5):2374-2390
Flunarizine suppresses Mycobacterium tuberculosis growth via calmodulin-dependent phagosome maturation.
Mo S, Liu X, Zhang K, Wang W, Cai Y, Ouyang Q, Zhu C, Lin D, Wan H, Li D, Wen Z, Chen X
Journal of leukocyte biology 2022 May;111(5):1021-1029
Journal of leukocyte biology 2022 May;111(5):1021-1029
Activation of the ATX/LPA/LPARs axis induces a fibrotic response in skeletal muscle.
Córdova-Casanova A, Cruz-Soca M, Chun J, Casar JC, Brandan E
Matrix biology : journal of the International Society for Matrix Biology 2022 May;109:121-139
Matrix biology : journal of the International Society for Matrix Biology 2022 May;109:121-139
Mitochondria-specific peptide amphiphiles induce mitochondrial dysfunction and peripheral T-cell lymphomas (PTCL) damage.
Sun Q, Gui A, Zou A, Yan Y, Qiu S, Zhu S, Liu W, Zuo J, Zhang Q, Yang L
Annals of translational medicine 2022 May;10(10):570
Annals of translational medicine 2022 May;10(10):570
Deletion of the miR-144/451 cluster aggravates lethal sepsis-induced lung epithelial oxidative stress and apoptosis.
Wu F, Yuan X, Liu W, Meng L, Li X, Gao X, Zhou S, Fang L, Yu D
Annals of translational medicine 2022 May;10(10):538
Annals of translational medicine 2022 May;10(10):538
Functional genetic screen identifies ITPR3/calcium/RELB axis as a driver of colorectal cancer metastatic liver colonization.
Moy RH, Nguyen A, Loo JM, Yamaguchi N, Kajba CM, Santhanam B, Ostendorf BN, Wu YG, Tavazoie S, Tavazoie SF
Developmental cell 2022 May 9;57(9):1146-1159.e7
Developmental cell 2022 May 9;57(9):1146-1159.e7
C/EBPβ mediates anti-proliferative effects of 1,25(OH)2D on differentiated thyroid carcinoma cells.
Xu F, Ling Y, Yuan J, Zeng Q, Li L, Dai D, Xia X, Sun R, Zhang R, Xie Z
Endocrine-related cancer 2022 May 9;29(6):321-334
Endocrine-related cancer 2022 May 9;29(6):321-334
PAFAH1B3 predicts poor prognosis and promotes progression in lung adenocarcinoma.
Tang S, Ni J, Chen B, Sun F, Huang J, Ni S, Tang Z
BMC cancer 2022 May 9;22(1):525
BMC cancer 2022 May 9;22(1):525
Oncopeptide MBOP Encoded by LINC01234 Promotes Colorectal Cancer through MAPK Signaling Pathway.
Tang C, Zhou Y, Sun W, Hu H, Liu Y, Chen L, Ou F, Zeng S, Lin N, Yu L
Cancers 2022 May 9;14(9)
Cancers 2022 May 9;14(9)
Gga-miR-30c-5p Enhances Apoptosis in Fowl Adenovirus Serotype 4-Infected Leghorn Male Hepatocellular Cells and Facilitates Viral Replication through Myeloid Cell Leukemia-1.
Haiyilati A, Zhou L, Li J, Li W, Gao L, Cao H, Wang Y, Li X, Zheng SJ
Viruses 2022 May 7;14(5)
Viruses 2022 May 7;14(5)
Hypoxic mesenchymal stem cell-derived extracellular vesicles ameliorate renal fibrosis after ischemia-reperfusion injure by restoring CPT1A mediated fatty acid oxidation.
Gao Z, Zhang C, Peng F, Chen Q, Zhao Y, Chen L, Wang X, Chen X
Stem cell research & therapy 2022 May 7;13(1):191
Stem cell research & therapy 2022 May 7;13(1):191
Nuclear and cytoplasmic poly(A) binding proteins (PABPs) favor distinct transcripts and isoforms.
Nicholson-Shaw AL, Kofman ER, Yeo GW, Pasquinelli AE
Nucleic acids research 2022 May 6;50(8):4685-4702
Nucleic acids research 2022 May 6;50(8):4685-4702
Z-DNA binding protein 1 promotes heatstroke-induced cell death.
Yuan F, Cai J, Wu J, Tang Y, Zhao K, Liang F, Li F, Yang X, He Z, Billiar TR, Wang H, Su L, Lu B
Science (New York, N.Y.) 2022 May 6;376(6593):609-615
Science (New York, N.Y.) 2022 May 6;376(6593):609-615
Cytochrome P450 2E1 predicts liver functional recovery from donation after circulatory death using air-ventilated normothermic machine perfusion.
Shi JH, Yang DJ, Jin Q, Cheng N, Shi YB, Bai Y, Yu DS, Guo WZ, Ge GB, Zhang SJ
Scientific reports 2022 May 6;12(1):7446
Scientific reports 2022 May 6;12(1):7446
Viperin triggers ribosome collision-dependent translation inhibition to restrict viral replication.
Hsu JC, Laurent-Rolle M, Pawlak JB, Xia H, Kunte A, Hee JS, Lim J, Harris LD, Wood JM, Evans GB, Shi PY, Grove TL, Almo SC, Cresswell P
Molecular cell 2022 May 5;82(9):1631-1642.e6
Molecular cell 2022 May 5;82(9):1631-1642.e6
FAM126A interacted with ENO1 mediates proliferation and metastasis in pancreatic cancer via PI3K/AKT signaling pathway.
Li Y, Li Y, Luo J, Fu X, Liu P, Liu S, Pan Y
Cell death discovery 2022 May 5;8(1):248
Cell death discovery 2022 May 5;8(1):248
The Cytoskeleton Effectors Rho-Kinase (ROCK) and Mammalian Diaphanous-Related (mDia) Formin Have Dynamic Roles in Tumor Microtube Formation in Invasive Glioblastoma Cells.
Becker KN, Pettee KM, Sugrue A, Reinard KA, Schroeder JL, Eisenmann KM
Cells 2022 May 5;11(9)
Cells 2022 May 5;11(9)
Dysregulation of the miR-30c/DLL4 axis by circHIPK3 is essential for KSHV lytic replication.
Harper KL, Mottram TJ, Anene CA, Foster B, Patterson MR, McDonnell E, Macdonald A, Westhead D, Whitehouse A
EMBO reports 2022 May 4;23(5):e54117
EMBO reports 2022 May 4;23(5):e54117
PFKP alleviates glucose starvation-induced metabolic stress in lung cancer cells via AMPK-ACC2 dependent fatty acid oxidation.
Chen J, Zou L, Lu G, Grinchuk O, Fang L, Ong DST, Taneja R, Ong CN, Shen HM
Cell discovery 2022 May 31;8(1):52
Cell discovery 2022 May 31;8(1):52
LXRα Regulates oxLDL-Induced Trained Immunity in Macrophages.
Findeisen HM, Voges VC, Braun LC, Sonnenberg J, Schwarz D, Körner H, Reinecke H, Sohrabi Y
International journal of molecular sciences 2022 May 31;23(11)
International journal of molecular sciences 2022 May 31;23(11)
Changes in the Transcriptome Caused by Mutations in the Ribosomal Protein uS10 Associated with a Predisposition to Colorectal Cancer.
Tian Y, Babaylova ES, Gopanenko AV, Tupikin AE, Kabilov MR, Malygin AA, Karpova GG
International journal of molecular sciences 2022 May 31;23(11)
International journal of molecular sciences 2022 May 31;23(11)
Natural antisense RNA Foxk1-AS promotes myogenic differentiation by inhibiting Foxk1 activity.
Li C, Shen H, Liu M, Li S, Luo Y
Cell communication and signaling : CCS 2022 May 31;20(1):77
Cell communication and signaling : CCS 2022 May 31;20(1):77
Poly(A)-Binding Protein Cytoplasmic 1 Inhibits Porcine Epidemic Diarrhea Virus Replication by Interacting with Nucleocapsid Protein.
Wu T, Wei X, Zheng S, She G, Han Z, Xu Z, Cao Y, Xue C
Viruses 2022 May 31;14(6)
Viruses 2022 May 31;14(6)
Comprehensive Analysis and Experimental Validation of a Novel Estrogen/Progesterone-Related Prognostic Signature for Endometrial Cancer.
Yu J, Yao HW, Liu TT, Wang D, Shi JH, Yuan GW, Ma S, Wu LY
Journal of personalized medicine 2022 May 31;12(6)
Journal of personalized medicine 2022 May 31;12(6)
The two-faced role of ATF2 on cisplatin response in gastric cancer depends on p53 context.
Xu L, Wang J, Zhang D, Song L, Wu H, Wang J, Miao J, Guo H, Fang S, Si L, Chen J, Wu Y, Wu Y, Wang L, Zhang N, Chard L, Wang Y, Cheng Z
Cell & bioscience 2022 May 31;12(1):77
Cell & bioscience 2022 May 31;12(1):77
Whole body vibration activates AMPK/CPT1 signaling pathway of skeletal muscle in young and aging mice based on metabolomics study.
Jiang D, Liu C, Chen Y, Xing X, Zheng D
Endocrine journal 2022 May 30;69(5):585-596
Endocrine journal 2022 May 30;69(5):585-596
Eukaryotic Initiation Factor 5A2 Regulates Expression of Antiviral Genes.
Farache D, Liu L, Lee ASY
Journal of molecular biology 2022 May 30;434(10):167564
Journal of molecular biology 2022 May 30;434(10):167564
The Establishment of a Mouse Model of Recurrent Primary Dysmenorrhea.
Hong F, He G, Zhang M, Yu B, Chai C
International journal of molecular sciences 2022 May 30;23(11)
International journal of molecular sciences 2022 May 30;23(11)
TGF-β1 regulates chondrocyte proliferation and extracellular matrix synthesis via circPhf21a-Vegfa axis in osteoarthritis.
Lin S, Li H, Wu B, Shang J, Jiang N, Peng R, Xing B, Xu X, Lu H
Cell communication and signaling : CCS 2022 May 30;20(1):75
Cell communication and signaling : CCS 2022 May 30;20(1):75
miR-600 promotes ovarian cancer cells stemness, proliferation and metastasis via targeting KLF9.
Shan L, Song P, Zhao Y, An N, Xia Y, Qi Y, Zhao H, Ge J
Journal of ovarian research 2022 May 3;15(1):52
Journal of ovarian research 2022 May 3;15(1):52
Pentamethylquercetin Regulates Lipid Metabolism by Modulating Skeletal Muscle-Adipose Tissue Crosstalk in Obese Mice.
Wu J, Du J, Li Z, He W, Wang M, Jin M, Yang L, Liu H
Pharmaceutics 2022 May 29;14(6)
Pharmaceutics 2022 May 29;14(6)
Hernandezine Regulates Proliferation and Autophagy-Induced Apoptosis in Melanoma Cells.
Wang X, Li X, Xia Y, Wang D, Li X, Liu L, Zheng Q, Li D, Jiang Q
Journal of natural products 2022 May 27;85(5):1351-1362
Journal of natural products 2022 May 27;85(5):1351-1362
Mechanism of INSR clustering with insulin activation and resistance revealed by super-resolution imaging.
Li H, Zhang J, Shi Y, Zhao G, Xu H, Cai M, Gao J, Wang H
Nanoscale 2022 May 26;14(20):7747-7755
Nanoscale 2022 May 26;14(20):7747-7755
β-amyloid protein induces mitophagy-dependent ferroptosis through the CD36/PINK/PARKIN pathway leading to blood-brain barrier destruction in Alzheimer's disease.
Li J, Li M, Ge Y, Chen J, Ma J, Wang C, Sun M, Wang L, Yao S, Yao C
Cell & bioscience 2022 May 26;12(1):69
Cell & bioscience 2022 May 26;12(1):69
TARDBP Inhibits Porcine Epidemic Diarrhea Virus Replication through Degrading Viral Nucleocapsid Protein and Activating Type I Interferon Signaling.
Dong S, Kong N, Zhang Y, Li Y, Sun D, Qin W, Zhai H, Zhai X, Yang X, Ye C, Ye M, Liu C, Yu L, Zheng H, Tong W, Yu H, Zhang W, Tong G, Shan T
Journal of virology 2022 May 25;96(10):e0007022
Journal of virology 2022 May 25;96(10):e0007022
Kif4A mediates resistance to neoadjuvant chemoradiotherapy in patients with advanced colorectal cancer via regulating DNA damage response.
Zhang R, Liu S, Gong B, Xie W, Zhao Y, Xu L, Zheng Y, Jin S, Ding C, Xu C, Dong Z
Acta biochimica et biophysica Sinica 2022 May 25;54(7):940-951
Acta biochimica et biophysica Sinica 2022 May 25;54(7):940-951
Cholecystectomy promotes colon carcinogenesis by activating the Wnt signaling pathway by increasing the deoxycholic acid level.
Yao Y, Li X, Xu B, Luo L, Guo Q, Wang X, Sun L, Zhang Z, Li P
Cell communication and signaling : CCS 2022 May 25;20(1):71
Cell communication and signaling : CCS 2022 May 25;20(1):71
Role of EZH2-mediated H3K27me3 in placental ADAM12-S expression: implications for fetoplacental growth.
Zhu YN, Gan XW, Pan F, Ni XT, Myatt L, Wang WS, Sun K
BMC medicine 2022 May 25;20(1):189
BMC medicine 2022 May 25;20(1):189
Aberrant methylmalonylation underlies methylmalonic acidemia and is attenuated by an engineered sirtuin.
Head PE, Myung S, Chen Y, Schneller JL, Wang C, Duncan N, Hoffman P, Chang D, Gebremariam A, Gucek M, Manoli I, Venditti CP
Science translational medicine 2022 May 25;14(646):eabn4772
Science translational medicine 2022 May 25;14(646):eabn4772
Role of Nrf2 Nucleus Translocation in Beauvericin-Induced Cell Damage in Rat Hepatocytes.
Shi J, Wang Y, Xu W, Cai G, Zou H, Yuan Y, Gu J, Liu Z, Bian J
Toxins 2022 May 25;14(6)
Toxins 2022 May 25;14(6)
FAT10 promotes chemotherapeutic resistance in pancreatic cancer by inducing epithelial-mesenchymal transition via stabilization of FOXM1 expression.
Zhu J, Zhao J, Luo C, Zhu Z, Peng X, Zhu X, Lin K, Bu F, Zhang W, Li Q, Wang K, Hu Z, Yu X, Chen L, Yuan R
Cell death & disease 2022 May 25;13(5):497
Cell death & disease 2022 May 25;13(5):497
Blocking STAT3 signaling augments MEK/ERK inhibitor efficacy in esophageal squamous cell carcinoma.
Zheng ZY, Chu MY, Lin W, Zheng YQ, Xu XE, Chen Y, Liao LD, Wu ZY, Wang SH, Li EM, Xu LY
Cell death & disease 2022 May 25;13(5):496
Cell death & disease 2022 May 25;13(5):496
MiR-135a-5p suppresses trophoblast proliferative, migratory, invasive, and angiogenic activity in the context of unexplained spontaneous abortion.
Lu Y, Zhang X, Li X, Deng L, Wei C, Yang D, Tan X, Pan W, Pang L
Reproductive biology and endocrinology : RB&E 2022 May 24;20(1):82
Reproductive biology and endocrinology : RB&E 2022 May 24;20(1):82
Brasilterpenes A-E, Bergamotane Sesquiterpenoid Derivatives with Hypoglycemic Activity from the Deep Sea-Derived Fungus Paraconiothyrium brasiliense HDN15-135.
Wang W, Shi Y, Liu Y, Zhang Y, Wu J, Zhang G, Che Q, Zhu T, Li M, Li D
Marine drugs 2022 May 23;20(5)
Marine drugs 2022 May 23;20(5)
Co-interventions with Clostridium butyricum and soluble dietary fiber targeting the gut microbiota improve MAFLD via the Acly/Nrf2/NF-κB signaling pathway.
Shao J, Ge T, Wei Y, Zhou Y, Shi M, Liu H, Chen Z, Xia Y
Food & function 2022 May 23;13(10):5807-5819
Food & function 2022 May 23;13(10):5807-5819
Blockade LAT1 Mediates Methionine Metabolism to Overcome Oxaliplatin Resistance under Hypoxia in Renal Cell Carcinoma.
Xu Q, Liu Y, Sun W, Song T, Jiang X, Zeng K, Zeng S, Chen L, Yu L
Cancers 2022 May 22;14(10)
Cancers 2022 May 22;14(10)
Sulforaphane protects myocardium from ischemia-reperfusion injury by regulating CaMKIIN2 and CaMKIIδ.
Zhang J, Dong Y, Zhou M, Wo X, Niu S, Shao E, Liu X, Jin H, Zhao W
Biochemical and biophysical research communications 2022 May 21;605:119-126
Biochemical and biophysical research communications 2022 May 21;605:119-126
Dedicator of Cytokinesis 2 (DOCK2) Silencing Protects Against Cerebral Ischemia/Reperfusion by Modulating Microglia Polarization via the Activation of the STAT6 Signaling Pathway.
Ding S, Cao Y, Lu X, Zhang H, Cong L, Yi T, Xu M, Wang L
Neuroscience 2022 May 21;491:110-121
Neuroscience 2022 May 21;491:110-121
METTL16 promotes hepatocellular carcinoma progression through downregulating RAB11B-AS1 in an m(6)A-dependent manner.
Dai YZ, Liu YD, Li J, Chen MT, Huang M, Wang F, Yang QS, Yuan JH, Sun SH
Cellular & molecular biology letters 2022 May 20;27(1):41
Cellular & molecular biology letters 2022 May 20;27(1):41
A comprehensive analysis of potential gastric cancer prognostic biomarker ITGBL1 associated with immune infiltration and epithelial-mesenchymal transition.
Wang Z, Fu L, Zhang J, Ge Y, Guo C, Wang R, Deng M, Wang Q, Wang Z
Biomedical engineering online 2022 May 20;21(1):30
Biomedical engineering online 2022 May 20;21(1):30
Inhibition of the CDK2 and Cyclin A complex leads to autophagic degradation of CDK2 in cancer cells.
Zhang J, Gan Y, Li H, Yin J, He X, Lin L, Xu S, Fang Z, Kim BW, Gao L, Ding L, Zhang E, Ma X, Li J, Li L, Xu Y, Horne D, Xu R, Yu H, Gu Y, Huang W
Nature communications 2022 May 20;13(1):2835
Nature communications 2022 May 20;13(1):2835
FBXW2 inhibits prostate cancer proliferation and metastasis via promoting EGFR ubiquitylation and degradation.
Zhou T, Chen T, Lai B, Zhang W, Luo X, Xia D, Fu W, Xu J
Cellular and molecular life sciences : CMLS 2022 May 2;79(5):268
Cellular and molecular life sciences : CMLS 2022 May 2;79(5):268
FNIP1 regulates adipocyte browning and systemic glucose homeostasis in mice by shaping intracellular calcium dynamics.
Yin Y, Xu D, Mao Y, Xiao L, Sun Z, Liu J, Zhou D, Xu Z, Liu L, Fu T, Ding C, Guo Q, Sun W, Zhou Z, Yang L, Jia Y, Chen X, Gan Z
The Journal of experimental medicine 2022 May 2;219(5)
The Journal of experimental medicine 2022 May 2;219(5)
Scorpion and centipede alleviates severe asthma through M2 macrophage-derived exosomal miR-30b-5p.
Tang B, Wu Y, Zhang Y, Cheng Y, Wu Y, Fang H
Aging 2022 May 2;14(9):3921-3940
Aging 2022 May 2;14(9):3921-3940
Pseudorabies Virus ICP0 Abolishes Tumor Necrosis Factor Alpha-Induced NF-κB Activation by Degrading P65.
Zhang X, Xie J, Gao M, Yan Z, Chen L, Wei S, Feng R
Viruses 2022 May 2;14(5)
Viruses 2022 May 2;14(5)
UHMK1 aids colorectal cancer cell proliferation and chemoresistance through augmenting IL-6/STAT3 signaling.
Gao X, Bao W, Bai J, Fan K, Li L, Li Y
Cell death & disease 2022 May 2;13(5):424
Cell death & disease 2022 May 2;13(5):424
Filamentous GLS1 promotes ROS-induced apoptosis upon glutamine deprivation via insufficient asparagine synthesis.
Jiang B, Zhang J, Zhao G, Liu M, Hu J, Lin F, Wang J, Zhao W, Ma H, Zhang C, Wu C, Yao L, Liu Q, Chen X, Cao Y, Zheng Y, Zhang C, Han A, Lin D, Li Q
Molecular cell 2022 May 19;82(10):1821-1835.e6
Molecular cell 2022 May 19;82(10):1821-1835.e6
Temporal regulation of interferon signalling in human EndoC-βH1 cells.
Dhayal S, Leslie KA, Baity M, Akhbari P, Richardson SJ, Russell MA, Morgan NG
Journal of molecular endocrinology 2022 May 19;69(2):299-313
Journal of molecular endocrinology 2022 May 19;69(2):299-313
Cystathionine-β-synthase (CBS)/H2S system promotes lymph node metastasis of esophageal squamous cell carcinoma (ESCC) by activating SIRT1.
Liu Y, Pan L, Li Y, Deng Y, Han X, Fu H, Wang T
Carcinogenesis 2022 May 19;43(4):382-392
Carcinogenesis 2022 May 19;43(4):382-392
Protective effect of homogeneous polysaccharides of Wuguchong (HPW) on intestinal mucositis induced by 5-fluorouracil in mice.
Shi P, Zhao T, Wang W, Peng F, Wang T, Jia Y, Zou L, Wang P, Yang S, Fan Y, Zong J, Qu X, Wang S
Nutrition & metabolism 2022 May 18;19(1):36
Nutrition & metabolism 2022 May 18;19(1):36
Human Protein-l-isoaspartate O-Methyltransferase Domain-Containing Protein 1 (PCMTD1) Associates with Cullin-RING Ligase Proteins.
Warmack RA, Pang EZ, Peluso E, Lowenson JD, Ong JY, Torres JZ, Clarke SG
Biochemistry 2022 May 17;61(10):879-894
Biochemistry 2022 May 17;61(10):879-894
BMP4 Exerts Anti-Neurogenic Effect via Inducing Id3 during Aging.
Li T, Liu H, Jiang D, Yang K, Shen J, Feng H, Wang S, Zhang Y, Wang Y, Tang TS
Biomedicines 2022 May 17;10(5)
Biomedicines 2022 May 17;10(5)
TFEB ameliorates autophagy flux disturbance induced by PBDE-47 via up-regulating autophagy-lysosome fusion.
Tang H, Huang H, Wang D, Li P, Tian Z, Li D, Wang S, Ma R, Xia T, Wang A
Journal of hazardous materials 2022 May 15;430:128483
Journal of hazardous materials 2022 May 15;430:128483
Exosomal miRNA-181a-5p from the cells of the hair follicle dermal papilla promotes the hair follicle growth and development via the Wnt/β-catenin signaling pathway.
Zhao B, Li J, Zhang X, Dai Y, Yang N, Bao Z, Chen Y, Wu X
International journal of biological macromolecules 2022 May 15;207:110-120
International journal of biological macromolecules 2022 May 15;207:110-120
Induction of p27 contributes to inhibitory effect of isorhapontigenin (ISO) on malignant transformation of human urothelial cells.
Huang M, Hua X, Xu J, Tian Z, Wang J, Chen H, Wang X, Shu P, Ye H, Shu J, Huang C
Cell cycle (Georgetown, Tex.) 2022 May 15;:1-14
Cell cycle (Georgetown, Tex.) 2022 May 15;:1-14
Circular RNA circRNF169 functions as a miR-30c-5p sponge to promote cellular senescence.
Zhang D, Li Y, Lei Y, Yang H, Huang L, Chen X, Zhou Z, Huang C, Zhou Y, Feng R, Xiong XD, Yuan Y, Cui H, Zheng HL, Sun X, Liu X, Xu S
Biochemical and biophysical research communications 2022 May 14;604:88-95
Biochemical and biophysical research communications 2022 May 14;604:88-95
A novel strategy for optimal component formula of anti-PRRSV from natural compounds using tandem mass tag labeled proteomic analyses.
Zhang H, Cao Z, Sun P, Khan A, Guo J, Sun Y, Yu X, Fan K, Yin W, Li E, Sun N, Li H
BMC veterinary research 2022 May 14;18(1):179
BMC veterinary research 2022 May 14;18(1):179
Mussel-inspired multifunctional surface through promoting osteogenesis and inhibiting osteoclastogenesis to facilitate bone regeneration.
Wu M, Zhang Y, Wu P, Chen F, Yang Z, Zhang S, Xiao L, Cai L, Zhang C, Chen Y, Deng Z
NPJ Regenerative medicine 2022 May 13;7(1):29
NPJ Regenerative medicine 2022 May 13;7(1):29
Impaired expression of BCAT1 relates to muscle atrophy of mouse model of sarcopenia.
Ouyang H, Gao X, Zhang J
BMC musculoskeletal disorders 2022 May 13;23(1):450
BMC musculoskeletal disorders 2022 May 13;23(1):450
VCP interaction with HMGB1 promotes hepatocellular carcinoma progression by activating the PI3K/AKT/mTOR pathway.
Pu Z, Duda DG, Zhu Y, Pei S, Wang X, Huang Y, Yi P, Huang Z, Peng F, Hu X, Fan X
Journal of translational medicine 2022 May 13;20(1):212
Journal of translational medicine 2022 May 13;20(1):212
Conformational Constrained 4-(1-Sulfonyl-3-indol)yl-2-phenylaminopyrimidine Derivatives as New Fourth-Generation Epidermal Growth Factor Receptor Inhibitors Targeting T790M/C797S Mutations.
Chen H, Lai M, Zhang T, Chen Y, Tong L, Zhu S, Zhou Y, Ren X, Ding J, Xie H, Lu X, Ding K
Journal of medicinal chemistry 2022 May 12;65(9):6840-6858
Journal of medicinal chemistry 2022 May 12;65(9):6840-6858
Human epididymis protein 4 aggravates airway inflammation and remodeling in chronic obstructive pulmonary disease.
Zhan Y, Chen J, Wu J, Gu Y, Huang Q, Deng Z, Chen S, Wu X, Lv Y, Zeng Z, Xie J
Respiratory research 2022 May 12;23(1):120
Respiratory research 2022 May 12;23(1):120
MRNIP condensates promote DNA double-strand break sensing and end resection.
Wang YL, Zhao WW, Bai SM, Feng LL, Bie SY, Gong L, Wang F, Wei MB, Feng WX, Pang XL, Qin CL, Yin XK, Wang YN, Zhou W, Wahl DR, Liu Q, Chen M, Hung MC, Wan XB
Nature communications 2022 May 12;13(1):2638
Nature communications 2022 May 12;13(1):2638
The A137R Protein of African Swine Fever Virus Inhibits Type I Interferon Production via the Autophagy-Mediated Lysosomal Degradation of TBK1.
Sun M, Yu S, Ge H, Wang T, Li Y, Zhou P, Pan L, Han Y, Yang Y, Sun Y, Li S, Li LF, Qiu HJ
Journal of virology 2022 May 11;96(9):e0195721
Journal of virology 2022 May 11;96(9):e0195721
Curcumin Derivative C66 Suppresses Pancreatic Cancer Progression through the Inhibition of JNK-Mediated Inflammation.
Chen H, Jiang Y, Liu R, Deng J, Chen Q, Chen L, Liang G, Chen X, Xu Z
Molecules (Basel, Switzerland) 2022 May 11;27(10)
Molecules (Basel, Switzerland) 2022 May 11;27(10)
Mrgprb2 gene plays a role in the anaphylactoid reactions induced by Houttuynia cordata injection.
Sun X, Lv W, Wang Y, Zhang X, Ouyang Z, Yin R, Wei Y
Journal of ethnopharmacology 2022 May 10;289:115053
Journal of ethnopharmacology 2022 May 10;289:115053
Inhibition of NOS1 promotes the interferon response of melanoma cells.
Chen X, Zou Z, Wang Q, Gao W, Zeng S, Ye S, Xu P, Huang M, Li K, Chen J, Zhong Z, Zhang Q, Hao B, Liu Q
Journal of translational medicine 2022 May 10;20(1):205
Journal of translational medicine 2022 May 10;20(1):205
FAM64A promotes HNSCC tumorigenesis by mediating transcriptional autoregulation of FOXM1.
Zhao X, Chen H, Qiu Y, Cui L
International journal of oral science 2022 May 10;14(1):25
International journal of oral science 2022 May 10;14(1):25
Vitamin C enhances the ex vivo proliferation of porcine muscle stem cells for cultured meat production.
Fang J, Li M, Zhang G, Du G, Zhou J, Guan X, Chen J
Food & function 2022 May 10;13(9):5089-5101
Food & function 2022 May 10;13(9):5089-5101
Long-read sequencing unveils high-resolution HPV integration and its oncogenic progression in cervical cancer.
Zhou L, Qiu Q, Zhou Q, Li J, Yu M, Li K, Xu L, Ke X, Xu H, Lu B, Wang H, Lu W, Liu P, Lu Y
Nature communications 2022 May 10;13(1):2563
Nature communications 2022 May 10;13(1):2563
PACS-2 Ameliorates Tubular Injury by Facilitating Endoplasmic Reticulum-Mitochondria Contact and Mitophagy in Diabetic Nephropathy.
Li C, Li L, Yang M, Yang J, Zhao C, Han Y, Zhao H, Jiang N, Wei L, Xiao Y, Liu Y, Xiong X, Xi Y, Luo S, Deng F, Chen W, Yuan S, Zhu X, Xiao L, Sun L
Diabetes 2022 May 1;71(5):1034-1050
Diabetes 2022 May 1;71(5):1034-1050
Exosomal miR-181a-2-3p derived from citreoviridin-treated hepatocytes activates hepatic stellate cells trough inducing mitochondrial calcium overload.
Dong Z, Yang X, Qiu T, An Y, Zhang G, Li Q, Jiang L, Yang G, Cao J, Sun X, Liu X, Liu D, Yao X
Chemico-biological interactions 2022 May 1;358:109899
Chemico-biological interactions 2022 May 1;358:109899
The RNA editing enzyme ADAR modulated by the rs1127317 genetic variant diminishes EGFR-TKIs efficiency in advanced lung adenocarcinoma.
Hua H, Zeng J, Xing H, He Y, Han L, Zhang N, Yang M
Life sciences 2022 May 1;296:120408
Life sciences 2022 May 1;296:120408
Active Release of eCIRP via Gasdermin D Channels to Induce Inflammation in Sepsis.
Tan C, Reilly B, Jha A, Murao A, Lee Y, Brenner M, Aziz M, Wang P
Journal of immunology (Baltimore, Md. : 1950) 2022 May 1;208(9):2184-2195
Journal of immunology (Baltimore, Md. : 1950) 2022 May 1;208(9):2184-2195
Paeoniflorin inhibits pyroptosis of nucleus pulposus cells in an acidic environment and alleviates the degeneration of the intervertebral disc in rats.
Dai WY, Luo ZP
Cellular signalling 2022 Mar;91:110243
Cellular signalling 2022 Mar;91:110243
A Selective Small-Molecule c-Myc Degrader Potently Regresses Lethal c-Myc Overexpressing Tumors.
Xu Y, Yu Q, Wang P, Wu Z, Zhang L, Wu S, Li M, Wu B, Li H, Zhuang H, Zhang X, Huang Y, Gan X, Xu R
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2022 Mar;9(8):e2104344
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2022 Mar;9(8):e2104344
Injectable self-healing hydrogel with siRNA delivery property for sustained STING silencing and enhanced therapy of intervertebral disc degeneration.
Chen J, Zhu H, Zhu Y, Zhao C, Wang S, Zheng Y, Xie Z, Jin Y, Song H, Yang L, Zhang J, Dai J, Hu Z, Wang H
Bioactive materials 2022 Mar;9:29-43
Bioactive materials 2022 Mar;9:29-43
miR-455-5p regulates circadian rhythms by accelerating the degradation of Clock mRNA.
Cheng Q, Fan X, Liu Y, Xu L, Dong P, Song L, Qian R
IUBMB life 2022 Mar;74(3):245-258
IUBMB life 2022 Mar;74(3):245-258
Attenuation of Activated eIF2α Signaling by ISRIB Treatment After Spinal Cord Injury Improves Locomotor Function.
Chang L, Liu X, Chen J, Liu H, Wang G, Wang G, Liao X, Shen X
Journal of molecular neuroscience : MN 2022 Mar;72(3):585-597
Journal of molecular neuroscience : MN 2022 Mar;72(3):585-597
Glycogen synthase kinase 3 beta inhibitor SB216763 improves Kir2.1 expression after myocardia infraction in rats.
Chang C, Wang SH, Xu LN, Su XL, Zeng YF, Wang P, Zhang LR, Han SN
Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing 2022 Mar;63(2):239-248
Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing 2022 Mar;63(2):239-248
MiR-15a-3p regulates ferroptosis via targeting glutathione peroxidase GPX4 in colorectal cancer.
Liu L, Yao H, Zhou X, Chen J, Chen G, Shi X, Wu G, Zhou G, He S
Molecular carcinogenesis 2022 Mar;61(3):301-310
Molecular carcinogenesis 2022 Mar;61(3):301-310
CD36 promotes de novo lipogenesis in hepatocytes through INSIG2-dependent SREBP1 processing.
Zeng H, Qin H, Liao M, Zheng E, Luo X, Xiao A, Li Y, Chen L, Wei L, Zhao L, Ruan XZ, Yang P, Chen Y
Molecular metabolism 2022 Mar;57:101428
Molecular metabolism 2022 Mar;57:101428
Scutellarein protects against cardiac hypertrophy via suppressing TRAF2/NF-κB signaling pathway.
Shi X, Hu Y, Jiang Y, Wu J, Zhang C, Zhang J, Wu S, Wu Y, Dong W, Li J
Molecular biology reports 2022 Mar;49(3):2085-2095
Molecular biology reports 2022 Mar;49(3):2085-2095
Exogenous adenosine activates A2A adenosine receptor to inhibit RANKL-induced osteoclastogenesis via AP-1 pathway to facilitate bone repair.
Cheng X, Yin C, Deng Y, Li Z
Molecular biology reports 2022 Mar;49(3):2003-2014
Molecular biology reports 2022 Mar;49(3):2003-2014
miR-1290 promotes IL-8-mediated vascular endothelial cell adhesion by targeting GSK-3β.
Xu H, Cui Y, Liu X, Zheng X, Liu J, Hu X, Gao F, Hu X, Li M, Wei X, Gao Y, Zhao Y
Molecular biology reports 2022 Mar;49(3):1871-1882
Molecular biology reports 2022 Mar;49(3):1871-1882
FERM domain-containing protein 6 exerts a tumor-inhibiting role in thyroid cancer by antagonizing oncogenic YAP1.
Wang W, Zhao C, Quan F, Zhang P, Shao Y, Liu L
BioFactors (Oxford, England) 2022 Mar;48(2):428-441
BioFactors (Oxford, England) 2022 Mar;48(2):428-441
Ginsenoside Rg3 ameliorates myocardial glucose metabolism and insulin resistance via activating the AMPK signaling pathway.
Ni J, Liu Z, Jiang M, Li L, Deng J, Wang X, Su J, Zhu Y, He F, Mao J, Gao X, Fan G
Journal of ginseng research 2022 Mar;46(2):235-247
Journal of ginseng research 2022 Mar;46(2):235-247
TRIM25 activates AKT/mTOR by inhibiting PTEN via K63-linked polyubiquitination in non-small cell lung cancer.
He YM, Zhou XM, Jiang SY, Zhang ZB, Cao BY, Liu JB, Zeng YY, Zhao J, Mao XL
Acta pharmacologica Sinica 2022 Mar;43(3):681-691
Acta pharmacologica Sinica 2022 Mar;43(3):681-691
Targeting a splicing-mediated drug resistance mechanism in prostate cancer by inhibiting transcriptional regulation by PKCβ1.
Melnyk JE, Steri V, Nguyen HG, Hwang YC, Gordan JD, Hann B, Feng FY, Shokat KM
Oncogene 2022 Mar;41(11):1536-1549
Oncogene 2022 Mar;41(11):1536-1549
YTHDF2 promotes multiple myeloma cell proliferation via STAT5A/MAP2K2/p-ERK axis.
Hua Z, Wei R, Guo M, Lin Z, Yu X, Li X, Gu C, Yang Y
Oncogene 2022 Mar;41(10):1482-1491
Oncogene 2022 Mar;41(10):1482-1491
SIRT1/mTOR pathway-mediated autophagy dysregulation promotes Pb-induced hepatic lipid accumulation in HepG2 cells.
Zhao Y, Mao A, Zhang R, Guan S, Lu J
Environmental toxicology 2022 Mar;37(3):549-563
Environmental toxicology 2022 Mar;37(3):549-563
Inhibition of Ras protein activator like 2 produces antitumor effects in gastric cancer via the suppression of YAP1 activation.
Hu Y, Zhang P, Shi Y, Dong X, Wu Y, Dong D, Li E, Fan Y
Environmental toxicology 2022 Mar;37(3):527-538
Environmental toxicology 2022 Mar;37(3):527-538
Neuroprotective Effects of Rhodiola Sacra on Transient Global Cerebral Ischemia Through Activating AMPK/Nrf2 Pathway in Rats.
Li K, Jiang J, Shi Z, Zhan L, Peng L, Sun W, Tang Y, Zuo X, Xu E
Antioxidants & redox signaling 2022 Mar;36(7-9):567-591
Antioxidants & redox signaling 2022 Mar;36(7-9):567-591
Mannose-binding lectin activates the nuclear factor-κB and renal inflammation in the progression of diabetic nephropathy.
Ma Y, Cai F, Huang X, Wang H, Yu B, Wang J, Nie W, Cai K, Yang Y, Chen J, Xiao L, Han F
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2022 Mar;36(3):e22227
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2022 Mar;36(3):e22227
ChK1 activation induces reactive astrogliosis through CIP2A/PP2A/STAT3 pathway in Alzheimer's disease.
Zhou Y, Liu X, Ma S, Zhang N, Yang D, Wang L, Ye S, Zhang Q, Ruan J, Ma J, Wang S, Jiang N, Zhao Z, Zhao S, Zheng C, Fan X, Gong Y, Abdoul Razak MY, Hu W, Pan J, Wang X, Fan J, Li J, Liu R, Shentu Y
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2022 Mar;36(3):e22209
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2022 Mar;36(3):e22209
Nicotinamide N-methyltransferase ameliorates renal fibrosis by its metabolite 1-methylnicotinamide inhibiting the TGF-β1/Smad3 pathway.
Zhang W, Rong G, Gu J, Fan C, Guo T, Jiang T, Deng W, Xie J, Su Z, Yu Q, Mai J, Zheng R, Chen X, Tang X, Zhang J
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2022 Mar;36(3):e22084
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2022 Mar;36(3):e22084
The LncRNA RP11-301G19.1/miR-582-5p/HMGB2 axis modulates the proliferation and apoptosis of multiple myeloma cancer cells via the PI3K/AKT signalling pathway.
Wang F, Luo Y, Zhang L, Younis M, Yuan L
Cancer gene therapy 2022 Mar;29(3-4):292-303
Cancer gene therapy 2022 Mar;29(3-4):292-303
Map, but not EspF, induces breast epithelial cell apoptosis through ERK/DRP-1 pathway.
Li Y, Zhu Y, Chu B, Liu N, Chen S, Wang J
Veterinary microbiology 2022 Mar;266:109367
Veterinary microbiology 2022 Mar;266:109367
NOX4 stimulates ANF secretion via activation of the Sirt1/Nrf2/ATF3/4 axis in hypoxic beating rat atria.
Li ZY, Liu Y, Wang YY, Li X, Han ZN, Hong L, Li YS, Cui X
Molecular medicine reports 2022 Mar;25(3)
Molecular medicine reports 2022 Mar;25(3)
Comparison of the effect of rotenone and 1‑methyl‑4‑phenyl‑1,2,3,6‑tetrahydropyridine on inducing chronic Parkinson's disease in mouse models.
Zhang J, Sun B, Yang J, Chen Z, Li Z, Zhang N, Li H, Shen L
Molecular medicine reports 2022 Mar;25(3)
Molecular medicine reports 2022 Mar;25(3)
Proteomic analysis of inhibitor of apoptosis protein‑like protein‑2 on breast cancer cell proliferation.
Xiang S, Zhu L, Zhang Z, Wang S, Cui R, Xiang M
Molecular medicine reports 2022 Mar;25(3)
Molecular medicine reports 2022 Mar;25(3)
Nicotine promotes chronic obstructive pulmonary disease via inducing pyroptosis activation in bronchial epithelial cells.
Mo R, Zhang J, Chen Y, Ding Y
Molecular medicine reports 2022 Mar;25(3)
Molecular medicine reports 2022 Mar;25(3)
Reversible phase separation of HSF1 is required for an acute transcriptional response during heat shock.
Zhang H, Shao S, Zeng Y, Wang X, Qin Y, Ren Q, Xiang S, Wang Y, Xiao J, Sun Y
Nature cell biology 2022 Mar;24(3):340-352
Nature cell biology 2022 Mar;24(3):340-352
Early Application of Quaternized Chitin Derivatives Inhibits Hypertrophic Scar Formation.
Chen Z, Xie F, Xia T, Bian X, Zhang S, Cai J, Wang Y
Macromolecular bioscience 2022 Mar;22(3):e2100418
Macromolecular bioscience 2022 Mar;22(3):e2100418
Optimization of the saffron compound essence formula and its effect on preventing skin photoaging.
Li Q, Liu L, Jiang S, Xu Z, Lin S, Tong Y, Wang P
Journal of cosmetic dermatology 2022 Mar;21(3):1251-1262
Journal of cosmetic dermatology 2022 Mar;21(3):1251-1262
Denatured Collagen Could Increase the Autophagy Level and Inhibit Apoptosis of Fibroblasts to Help Cell Survival and Influence Wound Healing.
Su Y, Li M, Wang X, Wang Z, Yi L
The international journal of lower extremity wounds 2022 Mar;21(1):92-99
The international journal of lower extremity wounds 2022 Mar;21(1):92-99
Inflammatory Injury and Mitophagy in the Cock Heart Induced by the Oral Administration of Hexavalent Chromium.
Wang Y, Wang L, Wang X, Cheng G, Xing Y, Zhang M, Zhang P, Liu J
Biological trace element research 2022 Mar;200(3):1312-1320
Biological trace element research 2022 Mar;200(3):1312-1320
Chk1 Inhibition Ameliorates Alzheimer's Disease Pathogenesis and Cognitive Dysfunction Through CIP2A/PP2A Signaling.
Hu W, Wang Z, Zhang H, Mahaman YAR, Huang F, Meng D, Zhou Y, Wang S, Jiang N, Xiong J, Westermarck J, Lu Y, Wang J, Wang X, Shentu Y, Liu R
Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics 2022 Mar;19(2):570-591
Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics 2022 Mar;19(2):570-591
TGM2 positively regulates myoblast differentiation via enhancing the mTOR signaling.
Wang D, Zhao D, Li Y, Dai T, Liu F, Yan C
Biochimica et biophysica acta. Molecular cell research 2022 Mar;1869(3):119173
Biochimica et biophysica acta. Molecular cell research 2022 Mar;1869(3):119173
MicroRNA-24-3p alleviates cardiac fibrosis by suppressing cardiac fibroblasts mitophagy via downregulating PHB2.
Zhang Y, Wang Z, Lan D, Zhao J, Wang L, Shao X, Wang D, Wu K, Sun M, Huang X, Yan M, Liang H, Rong X, Diao H, Guo J
Pharmacological research 2022 Mar;177:106124
Pharmacological research 2022 Mar;177:106124
Downregulation of the farnesoid X receptor promotes colorectal tumorigenesis by facilitating enterotoxigenic Bacteroides fragilis colonization.
Guo S, Peng Y, Lou Y, Cao L, Liu J, Lin N, Cai S, Kang Y, Zeng S, Yu L
Pharmacological research 2022 Mar;177:106101
Pharmacological research 2022 Mar;177:106101
E3 ubiquitin ligase Nedd4-2 exerts neuroprotective effects during endoplasmic reticulum stress.
Lodes DE, Zhu J, Tsai NP
Journal of neurochemistry 2022 Mar;160(6):613-624
Journal of neurochemistry 2022 Mar;160(6):613-624
Clinical significance of mitogen-activated protein kinase kinase kinases in hepatitis B virus -related hepatocellular carcinoma and underlying mechanism exploration.
Liu Z, Zhou X, Zheng P, Bu C, Yan X, Yu H, Xu Y
Bioengineered 2022 Mar;13(3):6819-6838
Bioengineered 2022 Mar;13(3):6819-6838
Low-density lipoprotein receptor-related protein 8 facilitates the proliferation and invasion of non-small cell lung cancer cells by regulating the Wnt/β-catenin signaling pathway.
Fang Z, Zhong M, Zhou L, Le Y, Wang H, Fang Z
Bioengineered 2022 Mar;13(3):6807-6818
Bioengineered 2022 Mar;13(3):6807-6818
TRIM21 deficiency promotes cell proliferation and tumorigenesis via regulating p21 expression in ovarian cancer.
Sun J, Chen X, Ji X, Meng S, Wang W, Wang P, Bai J, Li Z, Chen Y
Bioengineered 2022 Mar;13(3):6024-6035
Bioengineered 2022 Mar;13(3):6024-6035
MicroRNA-130a attenuates cardiac fibrosis after myocardial infarction through TGF-β/Smad signaling by directly targeting TGF-β receptor 1.
Feng Y, Bao Y, Ding J, Li H, Liu W, Wang X, Guan H, Chen Z
Bioengineered 2022 Mar;13(3):5779-5791
Bioengineered 2022 Mar;13(3):5779-5791
Effects of runt-related transcription factor 2 (RUNX2) on the autophagy of rapamycin-treated osteoblasts.
Ren C, Xu Y, Liu H, Wang Z, Ma T, Li Z, Sun L, Huang Q, Zhang K, Zhang C, Cui Y, Wang Q, Lu Y
Bioengineered 2022 Mar;13(3):5262-5276
Bioengineered 2022 Mar;13(3):5262-5276
Methylation recognition protein YTH N6-methyladenosine RNA binding protein 1 (YTHDF1) regulates the proliferation, migration and invasion of osteosarcoma by regulating m6A level of CCR4-NOT transcription complex subunit 7 (CNOT7).
Wei K, Gao Y, Wang B, Qu YX
Bioengineered 2022 Mar;13(3):5236-5250
Bioengineered 2022 Mar;13(3):5236-5250
Knockdown of mitochondrial threonyl-tRNA synthetase 2 inhibits lung adenocarcinoma cell proliferation and induces apoptosis.
Tian H, Yan H, Zhang Y, Fu Q, Li C, He J, Li H, Zhou Y, Huang Y, Li R
Bioengineered 2022 Mar;13(3):5190-5204
Bioengineered 2022 Mar;13(3):5190-5204
The expression profile of lung long non-coding RNAs and mRNAs in a mouse model of smoke inhalation injury.
Jiang ZY, Liu MZ, Fu ZH, Liao XC, Xu B, Shi LL, Li JQ, Guo GH
Bioengineered 2022 Mar;13(3):4978-4990
Bioengineered 2022 Mar;13(3):4978-4990
Overexpression of interleukin-10 in engineered macrophages protects endothelial cells against LPS-induced injury in vitro.
Yi L, Weng T, Nie P, Zhu L, Gao M, Jia H, Yang S, Li X, Zhang L, Xu Y, Ma P, Hu M
FEBS open bio 2022 Mar;12(3):605-615
FEBS open bio 2022 Mar;12(3):605-615
Targeting PFKL with penfluridol inhibits glycolysis and suppresses esophageal cancer tumorigenesis in an AMPK/FOXO3a/BIM-dependent manner.
Zheng C, Yu X, Liang Y, Zhu Y, He Y, Liao L, Wang D, Yang Y, Yin X, Li A, He Q, Li B
Acta pharmaceutica Sinica. B 2022 Mar;12(3):1271-1287
Acta pharmaceutica Sinica. B 2022 Mar;12(3):1271-1287
Venetoclax enhances NK cell killing sensitivity of AML cells through the NKG2D/NKG2DL activation pathway.
Wu HY, Li KX, Pan WY, Guo MQ, Qiu DZ, He YJ, Li YH, Huang YX
International immunopharmacology 2022 Mar;104:108497
International immunopharmacology 2022 Mar;104:108497
lncRNA EDAL restricts rabies lyssavirus replication in a cell-specific and infection route-dependent manner.
Sui B, Zhao J, Zheng J, Zhou M, Chen H, Fu ZF, Zhao L
The Journal of general virology 2022 Mar;103(3)
The Journal of general virology 2022 Mar;103(3)
Elucidation of pathological mechanism caused by human disease mutation in CaMKIIβ.
Mutoh H, Aoto K, Miyazaki T, Fukuda A, Saitsu H
Journal of neuroscience research 2022 Mar;100(3):880-896
Journal of neuroscience research 2022 Mar;100(3):880-896
The activation of SIRT3 by dexmedetomidine mitigates limb ischemia-reperfusion-induced lung injury.
Wang L, Ding Y, Bai Y, Shi J, Li J, Wang X
Annals of translational medicine 2022 Mar;10(6):319
Annals of translational medicine 2022 Mar;10(6):319
Immunomodulatory activity of aqueous extract from Crassostrea sikamea in the splenocytes of Sprague-Dawley rats.
Guo G, Kong Y, Su J, Wang G, Zhang M, Wang S, Song Z
Food science & nutrition 2022 Mar;10(3):813-821
Food science & nutrition 2022 Mar;10(3):813-821
Ubiquitin-specific protease 1 acts as an oncogene and promotes lenvatinib efficacy in hepatocellular carcinoma by stabilizing c-kit.
Chen Z, Ma Y, Guo Z, Song D, Chen Z, Sun M
Annals of hepatology 2022 Mar-Apr;27(2):100669
Annals of hepatology 2022 Mar-Apr;27(2):100669
Cur@SF NPs alleviate Friedreich's ataxia in a mouse model through synergistic iron chelation and antioxidation.
Xu L, Sun Z, Xing Z, Liu Y, Zhao H, Tang Z, Luo Y, Hao S, Li K
Journal of nanobiotechnology 2022 Mar 9;20(1):118
Journal of nanobiotechnology 2022 Mar 9;20(1):118
Moderate heart rate reduction promotes cardiac regeneration through stimulation of the metabolic pattern switch.
Tan J, Yang M, Wang H, Shen C, Wu M, Xu H, Wu Y, Li Y, Li X, Huang T, Deng S, Yang Z, Gao S, Li H, Zhou J, Chen H, Cao N, Cai W
Cell reports 2022 Mar 8;38(10):110468
Cell reports 2022 Mar 8;38(10):110468
MicroRNA-10b promotes arthritis development by disrupting CD4(+) T cell subtypes.
Tu J, Han D, Fang Y, Jiang H, Tan X, Xu Z, Wang X, Hong W, Li T, Wei W
Molecular therapy. Nucleic acids 2022 Mar 8;27:733-750
Molecular therapy. Nucleic acids 2022 Mar 8;27:733-750
LncEDCH1 improves mitochondrial function to reduce muscle atrophy by interacting with SERCA2.
Cai B, Ma M, Zhang J, Wang Z, Kong S, Zhou Z, Lian L, Zhang J, Li J, Wang Y, Li H, Zhang X, Nie Q
Molecular therapy. Nucleic acids 2022 Mar 8;27:319-334
Molecular therapy. Nucleic acids 2022 Mar 8;27:319-334
Overexpression of cytosolic long noncoding RNA cytb protects against pressure-overload-induced heart failure via sponging microRNA-103-3p.
Zhang X, Yuan S, Liu J, Tang Y, Wang Y, Zhan J, Fan J, Nie X, Zhao Y, Wen Z, Li H, Chen C, Wang DW
Molecular therapy. Nucleic acids 2022 Mar 8;27:1127-1145
Molecular therapy. Nucleic acids 2022 Mar 8;27:1127-1145
YB1 associates with oncogenetic roles and poor prognosis in nasopharyngeal carcinoma.
Zhan Y, Chen X, Zheng H, Luo J, Yang Y, Ning Y, Wang H, Zhang Y, Zhou M, Wang W, Fan S
Scientific reports 2022 Mar 8;12(1):3699
Scientific reports 2022 Mar 8;12(1):3699
Gene therapy of yeast NDI1 on mitochondrial complex I dysfunction in rotenone-induced Parkinson's disease models in vitro and vivo.
Li H, Sun B, Huang Y, Zhang J, Xu X, Shen Y, Chen Z, Yang J, Shen L, Hu Y, Gu H
Molecular medicine (Cambridge, Mass.) 2022 Mar 7;28(1):29
Molecular medicine (Cambridge, Mass.) 2022 Mar 7;28(1):29
The fiber diameter traits of Tibetan cashmere goats are governed by the inherent differences in stress, hypoxic, and metabolic adaptations: an integrative study of proteome and transcriptome.
Zhao B, Wu C, Sammad A, Ma Z, Suo L, Wu Y, Fu X
BMC genomics 2022 Mar 7;23(1):191
BMC genomics 2022 Mar 7;23(1):191
Karyopherin enrichment and compensation fortifies the nuclear pore complex against nucleocytoplasmic leakage.
Kalita J, Kapinos LE, Zheng T, Rencurel C, Zilman A, Lim RYH
The Journal of cell biology 2022 Mar 7;221(3)
The Journal of cell biology 2022 Mar 7;221(3)
Blocking protease-activated receptor 4 alleviates liver injury induced by brain death.
Fang H, Yuan Z, Zhu Y, Tang H, Pang C, Li J, Shi J, Guo W, Zhang S
Biochemical and biophysical research communications 2022 Mar 5;595:47-53
Biochemical and biophysical research communications 2022 Mar 5;595:47-53
Simvastatin Downregulates Cofilin and Stathmin to Inhibit Skeletal Muscle Cells Migration.
Lin LP, Yu TY, Chang HN, Tsai WC, Pang JS
International journal of molecular sciences 2022 Mar 5;23(5)
International journal of molecular sciences 2022 Mar 5;23(5)
A CFH peptide-decorated liposomal oxymatrine inactivates cancer-associated fibroblasts of hepatocellular carcinoma through epithelial-mesenchymal transition reversion.
Guo J, Zeng H, Shi X, Han T, Liu Y, Liu Y, Liu C, Qu D, Chen Y
Journal of nanobiotechnology 2022 Mar 5;20(1):114
Journal of nanobiotechnology 2022 Mar 5;20(1):114
Continuous ZnO nanoparticle exposure induces melanoma-like skin lesions in epidermal barrier dysfunction model mice through anti-apoptotic effects mediated by the oxidative stress-activated NF-κB pathway.
Wang P, Hu G, Zhao W, Du J, You M, Xv M, Yang H, Zhang M, Yan F, Huang M, Wang X, Zhang L, Chen Y
Journal of nanobiotechnology 2022 Mar 5;20(1):111
Journal of nanobiotechnology 2022 Mar 5;20(1):111
Inhibition of RIP3 increased ADSC viability under OGD and modified the competency of adipogenesis, angiogenesis, and inflammation regulation.
Yang Z, Qi Z, Yang X, Gao Q, Hu Y, Yuan X
Bioscience reports 2022 Mar 31;42(3)
Bioscience reports 2022 Mar 31;42(3)
Curcuminoids Inhibit Angiogenic Behaviors of Human Umbilical Vein Endothelial Cells via Endoglin/Smad1 Signaling.
Chou YF, Lan YH, Hsiao JH, Chen CY, Chou PY, Sheu MJ
International journal of molecular sciences 2022 Mar 31;23(7)
International journal of molecular sciences 2022 Mar 31;23(7)
Exercise Ameliorates Atherosclerosis via Up-Regulating Serum β-Hydroxybutyrate Levels.
Xu Z, Zhang M, Li X, Wang Y, Du R
International journal of molecular sciences 2022 Mar 30;23(7)
International journal of molecular sciences 2022 Mar 30;23(7)
PTIP governs NAD(+) metabolism by regulating CD38 expression to drive macrophage inflammation.
Wang Q, Hu J, Han G, Wang P, Li S, Chang J, Gao K, Yin R, Li Y, Zhang T, Chai J, Gao Z, Zhang T, Cheng Y, Guo C, Wang J, Liu W, Cui M, Xu Y, Hou J, Zhu QF, Feng YQ, Zhang H
Cell reports 2022 Mar 29;38(13):110603
Cell reports 2022 Mar 29;38(13):110603
NMDA receptor-dependent prostaglandin-endoperoxide synthase 2 induction in neurons promotes glial proliferation during brain development and injury.
Zhou J, Geng Y, Su T, Wang Q, Ren Y, Zhao J, Fu C, Weber M, Lin H, Kaminker JS, Liu N, Sheng M, Chen Y
Cell reports 2022 Mar 29;38(13):110557
Cell reports 2022 Mar 29;38(13):110557
Combined exposure to fine particulate matter and high glucose aggravates endothelial damage by increasing inflammation and mitophagy: the involvement of vitamin D.
Lai TC, Chen YC, Cheng HH, Lee TL, Tsai JS, Lee IT, Peng KT, Lee CW, Hsu LF, Chen YL
Particle and fibre toxicology 2022 Mar 29;19(1):25
Particle and fibre toxicology 2022 Mar 29;19(1):25
HBx inhibits DNA sensing signaling pathway via ubiquitination and autophagy of cGAS.
Chen H, Jiang L, Chen S, Hu Q, Huang Y, Wu Y, Chen W
Virology journal 2022 Mar 28;19(1):55
Virology journal 2022 Mar 28;19(1):55
SPIONs mediated magnetic actuation promotes nerve regeneration by inducing and maintaining repair-supportive phenotypes in Schwann cells.
Liu T, Wang Y, Lu L, Liu Y
Journal of nanobiotechnology 2022 Mar 27;20(1):159
Journal of nanobiotechnology 2022 Mar 27;20(1):159
Prognostic significance of SNCA and its methylation in bladder cancer.
Wu Z, Xia C, Zhang C, Yang D, Ma K
BMC cancer 2022 Mar 26;22(1):330
BMC cancer 2022 Mar 26;22(1):330
Mesenchymal stem cells protect against ferroptosis via exosome-mediated stabilization of SLC7A11 in acute liver injury.
Lin F, Chen W, Zhou J, Zhu J, Yao Q, Feng B, Feng X, Shi X, Pan Q, Yu J, Li L, Cao H
Cell death & disease 2022 Mar 26;13(3):271
Cell death & disease 2022 Mar 26;13(3):271
Fucoxanthin Attenuates Free Fatty Acid-Induced Nonalcoholic Fatty Liver Disease by Regulating Lipid Metabolism/Oxidative Stress/Inflammation via the AMPK/Nrf2/TLR4 Signaling Pathway.
Ye J, Zheng J, Tian X, Xu B, Yuan F, Wang B, Yang Z, Huang F
Marine drugs 2022 Mar 25;20(4)
Marine drugs 2022 Mar 25;20(4)
Estrogen inhibits endoplasmic reticulum stress and ameliorates myocardial ischemia/reperfusion injury in rats by upregulating SERCA2a.
Chen J, Liu Y, Pan D, Xu T, Luo Y, Wu W, Wu P, Zhu H, Li D
Cell communication and signaling : CCS 2022 Mar 24;20(1):38
Cell communication and signaling : CCS 2022 Mar 24;20(1):38
Remodeling of dermal adipose tissue alleviates cutaneous toxicity induced by anti-EGFR therapy.
Chen L, You Q, Liu M, Li S, Wu Z, Hu J, Ma Y, Xia L, Zhou Y, Xu N, Zhang S
eLife 2022 Mar 24;11
eLife 2022 Mar 24;11
Tumor Susceptibility Gene 101 (TSG101) Contributes to Virion Formation of Porcine Reproductive and Respiratory Syndrome Virus via Interaction with the Nucleocapsid (N) Protein along with the Early Secretory Pathway.
Zhang L, Li R, Geng R, Wang L, Chen XX, Qiao S, Zhang G
Journal of virology 2022 Mar 23;96(6):e0000522
Journal of virology 2022 Mar 23;96(6):e0000522
Ferroptosis, a new target for treatment of renal injury and fibrosis in a 5/6 nephrectomy-induced CKD rat model.
Wang J, Wang Y, Liu Y, Cai X, Huang X, Fu W, Wang L, Qiu L, Li J, Sun L
Cell death discovery 2022 Mar 22;8(1):127
Cell death discovery 2022 Mar 22;8(1):127
Presence of CrkI-containing microvesicles in squamous cell carcinomas could have ramifications on tumor biology and cancer therapeutics.
Mohamed MF, Al-Khudari S, Cassini-Vieira P, Erra A, Bagabas R, Houser T, Stenson K, Bhayani M, Jelinek MJ, Bishehsari F, Kuzel TM, Shafikhani SH
Scientific reports 2022 Mar 21;12(1):4803
Scientific reports 2022 Mar 21;12(1):4803
lncRNA HITT inhibits metastasis by attenuating Rab5-mediated endocytosis in lung adenocarcinoma.
Wang X, Zheng S, Yang F, Zhang W, Zhao D, Xue X, Lin Q, He Y, Hu G, Hu Y
Molecular therapy : the journal of the American Society of Gene Therapy 2022 Mar 2;30(3):1071-1088
Molecular therapy : the journal of the American Society of Gene Therapy 2022 Mar 2;30(3):1071-1088
Exosome-derived circTRPS1 promotes malignant phenotype and CD8+ T cell exhaustion in bladder cancer microenvironments.
Yang C, Wu S, Mou Z, Zhou Q, Dai X, Ou Y, Chen X, Chen Y, Xu C, Hu Y, Zhang L, Zou L, Jin S, Hu J, Mao S, Jiang H
Molecular therapy : the journal of the American Society of Gene Therapy 2022 Mar 2;30(3):1054-1070
Molecular therapy : the journal of the American Society of Gene Therapy 2022 Mar 2;30(3):1054-1070
Heat Stress Impairs Maternal Endometrial Integrity and Results in Embryo Implantation Failure by Regulating Transport-Related Gene Expression in Tongcheng Pigs.
Lian W, Gao D, Huang C, Zhong Q, Hua R, Lei M
Biomolecules 2022 Mar 2;12(3)
Biomolecules 2022 Mar 2;12(3)
SLC4A4 promotes prostate cancer progression in vivo and in vitro via AKT-mediated signalling pathway.
Liu Z, Wang Q, Zhai G, Ke S, Yu X, Guo J
Cancer cell international 2022 Mar 19;22(1):127
Cancer cell international 2022 Mar 19;22(1):127
PINK1/TAX1BP1-directed mitophagy attenuates vascular endothelial injury induced by copper oxide nanoparticles.
Fan Y, Cheng Z, Mao L, Xu G, Li N, Zhang M, Weng P, Zheng L, Dong X, Hu S, Wang B, Qin X, Jiang X, Chen C, Zhang J, Zou Z
Journal of nanobiotechnology 2022 Mar 19;20(1):149
Journal of nanobiotechnology 2022 Mar 19;20(1):149
Claudin1 decrease induced by 1,25-dihydroxy-vitamin D3 potentiates gefitinib resistance therapy through inhibiting AKT activation-mediated cancer stem-like properties in NSCLC cells.
Jia Z, Wang K, Duan Y, Hu K, Zhang Y, Wang M, Xiao K, Liu S, Pan Z, Ding X
Cell death discovery 2022 Mar 18;8(1):122
Cell death discovery 2022 Mar 18;8(1):122
Duck plague virus UL41 protein inhibits RIG-I/MDA5-mediated duck IFN-β production via mRNA degradation activity.
He T, Wang M, Cheng A, Yang Q, Wu Y, Jia R, Chen S, Zhu D, Liu M, Zhao X, Zhang S, Huang J, Tian B, Ou X, Mao S, Sun D, Gao Q, Yu Y, Zhang L, Liu Y
Veterinary research 2022 Mar 18;53(1):22
Veterinary research 2022 Mar 18;53(1):22
Dynamic control of chromatin-associated m(6)A methylation regulates nascent RNA synthesis.
Xu W, He C, Kaye EG, Li J, Mu M, Nelson GM, Dong L, Wang J, Wu F, Shi YG, Adelman K, Lan F, Shi Y, Shen H
Molecular cell 2022 Mar 17;82(6):1156-1168.e7
Molecular cell 2022 Mar 17;82(6):1156-1168.e7
Synthetic mRNA-based gene therapy for glioblastoma: TRAIL-mRNA synergistically enhances PTEN-mRNA-based therapy.
Tang X, Peng H, Xu P, Zhang L, Fu R, Tu H, Guo X, Huang K, Lu J, Chen H, Dong Z, Dai L, Luo J, Chen Q
Molecular therapy oncolytics 2022 Mar 17;24:707-718
Molecular therapy oncolytics 2022 Mar 17;24:707-718
Comprehensive analysis of FKBP4/NR3C1/TMEM173 signaling pathway in triple-negative breast cancer cell and dendritic cell among tumor microenvironment.
Xiong H, Chen Z, Lin B, Chen W, Li Q, Li Y, Fang M, Wang Y, Zhang H, Lu Y, Bi A, Wu S, Jia Y, Wang X
Molecular therapy oncolytics 2022 Mar 17;24:371-384
Molecular therapy oncolytics 2022 Mar 17;24:371-384
Intracranial delivery of synthetic mRNA to suppress glioblastoma.
Peng H, Guo X, He J, Duan C, Yang M, Zhang X, Zhang L, Fu R, Wang B, Wang D, Chen H, Xie M, Feng P, Dai L, Tang X, Luo J
Molecular therapy oncolytics 2022 Mar 17;24:160-170
Molecular therapy oncolytics 2022 Mar 17;24:160-170
A Distinct Metabolically Defined Central Nucleus Circuit Bidirectionally Controls Anxiety-Related Behaviors.
Ren J, Lu CL, Huang J, Fan J, Guo F, Mo JW, Huang WY, Kong PL, Li XW, Sun LR, Sun XD, Cao X
The Journal of neuroscience : the official journal of the Society for Neuroscience 2022 Mar 16;42(11):2356-2370
The Journal of neuroscience : the official journal of the Society for Neuroscience 2022 Mar 16;42(11):2356-2370
IGF-1 Signaling Regulates Mitochondrial Remodeling during Myogenic Differentiation.
Guan X, Yan Q, Wang D, Du G, Zhou J
Nutrients 2022 Mar 16;14(6)
Nutrients 2022 Mar 16;14(6)
Daidzein suppresses TGF-β1-induced cardiac fibroblast activation via the TGF-β1/SMAD2/3 signaling pathway.
Shu J, Hu L, Wu Y, Chen L, Huang K, Wang Z, Liang M
European journal of pharmacology 2022 Mar 15;919:174805
European journal of pharmacology 2022 Mar 15;919:174805
DL0805-1, a novel Rho-kinase inhibitor, attenuates lung injury and vasculopathy in a rat model of monocrotaline-induced pulmonary hypertension.
Chen D, Yuan T, Chen Y, Zhang H, Niu Z, Fang L, Du G
European journal of pharmacology 2022 Mar 15;919:174779
European journal of pharmacology 2022 Mar 15;919:174779
EBV Infection in Epithelial Malignancies Induces Resistance to Antitumor Natural Killer Cells via F3-Mediated Platelet Aggregation.
Duan X, Chen H, Zhou X, Liu P, Zhang X, Zhu Q, Zhong L, Zhang W, Zhang S, Zhang X, Chen Y, Zhou Y, Yang C, Feng Q, Zeng YX, Xu M, Xiang T
Cancer research 2022 Mar 15;82(6):1070-1083
Cancer research 2022 Mar 15;82(6):1070-1083
RAD51 is essential for spermatogenesis and male fertility in mice.
Qin J, Huang T, Wang J, Xu L, Dang Q, Xu X, Liu H, Liu Z, Shao C, Zhang X
Cell death discovery 2022 Mar 15;8(1):118
Cell death discovery 2022 Mar 15;8(1):118
Salvia miltiorrhiza polysaccharides alleviates florfenicol induced kidney injury in chicks via inhibiting oxidative stress and apoptosis.
Wang X, Liu W, Jin G, Wu Z, Zhang D, Bao Y, Shi W
Ecotoxicology and environmental safety 2022 Mar 15;233:113339
Ecotoxicology and environmental safety 2022 Mar 15;233:113339
TMEM106B deficiency impairs cerebellar myelination and synaptic integrity with Purkinje cell loss.
Feng T, Luan L, Katz II, Ullah M, Van Deerlin VM, Trojanowski JQ, Lee EB, Hu F
Acta neuropathologica communications 2022 Mar 14;10(1):33
Acta neuropathologica communications 2022 Mar 14;10(1):33
S100A16 promotes acute kidney injury by activating HRD1-induced ubiquitination and degradation of GSK3β and CK1α.
Sun Y, Fan Y, Wang Z, Li M, Su D, Liu Y, Liang X
Cellular and molecular life sciences : CMLS 2022 Mar 12;79(3):184
Cellular and molecular life sciences : CMLS 2022 Mar 12;79(3):184
Antagonistic L1 Adhesion Molecule Mimetic Compounds Inhibit Glioblastoma Cell Migration In Vitro.
Nagaraj V, Mikhail M, Baronio M, Gatto A, Nayak A, Theis T, Cavallaro U, Schachner M
Biomolecules 2022 Mar 12;12(3)
Biomolecules 2022 Mar 12;12(3)
2-Fluorofucose Attenuates Hydrogen Peroxide-Induced Oxidative Stress in HepG2 Cells via Nrf2/keap1 and NF-κB Signaling Pathways.
Tu M, Fan X, Shi J, Jing S, Xu X, Wang Y
Life (Basel, Switzerland) 2022 Mar 11;12(3)
Life (Basel, Switzerland) 2022 Mar 11;12(3)
Environmental cadmium impairs blood-testis barrier via activating HRI-responsive mitochondrial stress in mice.
Zhou GX, Liu WB, Dai LM, Zhu HL, Xiong YW, Li DX, Xu DX, Wang H
The Science of the total environment 2022 Mar 1;810:152247
The Science of the total environment 2022 Mar 1;810:152247
Targeting macrophage TFEB-14-3-3 epsilon Interface by naringenin inhibits abdominal aortic aneurysm.
Jia Y, Zhang L, Liu Z, Mao C, Ma Z, Li W, Yu F, Wang Y, Huang Y, Zhang W, Zheng J, Wang X, Xu Q, Zhang J, Feng W, Yun C, Liu C, Sun J, Fu Y, Cui Q, Kong W
Cell discovery 2022 Mar 1;8(1):21
Cell discovery 2022 Mar 1;8(1):21
Vitamin D receptor regulates proliferation and differentiation of thyroid carcinoma via the E-cadherin-β-catenin complex.
Ling Y, Xu F, Xia X, Dai D, Sun R, Xie Z
Journal of molecular endocrinology 2022 Mar 1;68(3):137-151
Journal of molecular endocrinology 2022 Mar 1;68(3):137-151
Lipoxin A(4) and its analog attenuate high fat diet-induced atherosclerosis via Keap1/Nrf2 pathway.
Xu F, Zhang J, Zhou X, Hao H
Experimental cell research 2022 Mar 1;412(1):113025
Experimental cell research 2022 Mar 1;412(1):113025
Isoxanthohumol, a component of Sophora flavescens, promotes the activation of the NLRP3 inflammasome and induces idiosyncratic hepatotoxicity.
Lin L, Chen Y, Li Q, Xu G, Ding K, Ren L, Shi W, Wang Y, Li Z, Dai W, Wei Z, Yang Y, Bai Z, Xiao X
Journal of ethnopharmacology 2022 Mar 1;285:114796
Journal of ethnopharmacology 2022 Mar 1;285:114796
C3/C3aR inhibition alleviates GMH-IVH-induced hydrocephalus by preventing microglia-astrocyte interactions in neonatal rats.
Tang J, Jila S, Luo T, Zhang B, Miao H, Feng H, Chen Z, Zhu G
Neuropharmacology 2022 Mar 1;205:108927
Neuropharmacology 2022 Mar 1;205:108927
Rescuing ischemic stroke by biomimetic nanovesicles through accelerated thrombolysis and sequential ischemia-reperfusion protection.
Yu W, Yin N, Yang Y, Xuan C, Liu X, Liu W, Zhang Z, Zhang K, Liu J, Shi J
Acta biomaterialia 2022 Mar 1;140:625-640
Acta biomaterialia 2022 Mar 1;140:625-640
ADAR1 inhibits adipogenesis and obesity by interacting with Dicer to promote the maturation of miR-155-5P.
Yu Z, Luo R, Li Y, Li X, Yang Z, Peng J, Huang K
Journal of cell science 2022 Mar 1;135(5)
Journal of cell science 2022 Mar 1;135(5)
Upregulation of BRD7 protects podocytes against high glucose-induced apoptosis by enhancing Nrf2 in a GSK-3β-dependent manner.
Yu X, Jiang N, Li J, Li X, He S
Tissue & cell 2022 Jun;76:101813
Tissue & cell 2022 Jun;76:101813
Piezo1 and IFT88 synergistically regulate mandibular condylar chondrocyte differentiation under cyclic tensile strain.
Zhang Z, Sa G, Wang Z, Wei Z, Zheng L, Zhang R, Zhu X, Yang X
Tissue & cell 2022 Jun;76:101781
Tissue & cell 2022 Jun;76:101781
Deactivation of AKT/GSK-3β-mediated Wnt/β-catenin pathway by silencing of KIF26B weakens the malignant behaviors of non-small cell lung cancer.
Chen N, Wu Q, Zhang G, Fu J, Geng Q, Zhang Y
Tissue & cell 2022 Jun;76:101750
Tissue & cell 2022 Jun;76:101750
CD146 as a promising therapeutic target for retinal and choroidal neovascularization diseases.
Xue B, Wang P, Yu W, Feng J, Li J, Zhao R, Yang Z, Yan X, Duan H
Science China. Life sciences 2022 Jun;65(6):1157-1170
Science China. Life sciences 2022 Jun;65(6):1157-1170
ADAR1 masks the cancer immunotherapeutic promise of ZBP1-driven necroptosis.
Zhang T, Yin C, Fedorov A, Qiao L, Bao H, Beknazarov N, Wang S, Gautam A, Williams RM, Crawford JC, Peri S, Studitsky V, Beg AA, Thomas PG, Walkley C, Xu Y, Poptsova M, Herbert A, Balachandran S
Nature 2022 Jun;606(7914):594-602
Nature 2022 Jun;606(7914):594-602
Butyrate supplementation regulates expression of chromosome segregation 1‑like protein to reverse the genetic distortion caused by p53 mutations in colorectal cancer.
Chang CC, Kao WY, Liu CY, Su HH, Kan YA, Lin PY, Ku WC, Chang KW, Yang RN, Huang CJ
International journal of oncology 2022 Jun;60(6)
International journal of oncology 2022 Jun;60(6)
Astaxanthin attenuates contrast-induced acute kidney injury in rats via ROS/NLRP3 inflammasome.
Song L, Yao S, Zheng D, Xuan Y, Li W
International urology and nephrology 2022 Jun;54(6):1355-1364
International urology and nephrology 2022 Jun;54(6):1355-1364
Suppression of ATG4B by copper inhibits autophagy and involves in Mallory body formation.
Xia F, Fu Y, Xie H, Chen Y, Fang D, Zhang W, Liu P, Li M
Redox biology 2022 Jun;52:102284
Redox biology 2022 Jun;52:102284
Pyrimethamine inhibits cell growth by inducing cell senescence and boosting CD8(+) T-cell mediated cytotoxicity in colorectal cancer.
Dong H, Hu L, Li W, Shi M, He L, Wang C, Hu Y, Wang H, Wen C, Liu H, Yang X
Molecular biology reports 2022 Jun;49(6):4281-4292
Molecular biology reports 2022 Jun;49(6):4281-4292
Atorvastatin reduces IOP in ocular hypertension in vivo and suppresses ECM in trabecular meshwork perhaps via FGD4.
Song XY, Chen YY, Liu WT, Cong L, Zhang JL, Zhang Y, Zhang YY
International journal of molecular medicine 2022 Jun;49(6)
International journal of molecular medicine 2022 Jun;49(6)
Schwann cell‑like cells derived from human amniotic mesenchymal stem cells promote sciatic nerve repair through an exosome‑induced SOX2/FN1 pathway in vitro.
Chen W, Chang S, Yang C, Zhou J, Zhang H, Nie K, Wei Z
International journal of molecular medicine 2022 Jun;49(6)
International journal of molecular medicine 2022 Jun;49(6)
ER Stress is Involved in Mast Cells Degranulation via IRE1α/miR-125/Lyn Pathway in an Experimental Intracerebral Hemorrhage Mouse Model.
Yang Z, Huang J, Liao Y, Gan S, Zhu S, Xu S, Shu Y, Lu W
Neurochemical research 2022 Jun;47(6):1598-1609
Neurochemical research 2022 Jun;47(6):1598-1609
LINC02154 promotes the proliferation and metastasis of hepatocellular carcinoma by enhancing SPC24 promoter activity and activating the PI3K-AKT signaling pathway.
Yue H, Wu K, Liu K, Gou L, Huang A, Tang H
Cellular oncology (Dordrecht, Netherlands) 2022 Jun;45(3):447-462
Cellular oncology (Dordrecht, Netherlands) 2022 Jun;45(3):447-462
MiR-15p-5p Mediates the Coordination of ICAM-1 and FAK to Promote Endothelial Cell Proliferation and Migration.
Gu W, Zhang L, Zhang X, Wang B, Shi X, Hu K, Ye Y, Liu G
Inflammation 2022 Jun;45(3):1402-1417
Inflammation 2022 Jun;45(3):1402-1417
Transcription Factor Specificity Protein 1 Regulates Inflammation and Fibrin Deposition in Nasal Polyps Via the Regulation of microRNA-125b and the Wnt/β-catenin Signaling Pathway.
Song L, Wang X, Qu X, Lv C
Inflammation 2022 Jun;45(3):1118-1132
Inflammation 2022 Jun;45(3):1118-1132
GPCR-mediated EGFR transactivation ameliorates skin toxicities induced by afatinib.
Chen LY, You Q, Lv DZ, Li SH, Zhang SY
Acta pharmacologica Sinica 2022 Jun;43(6):1534-1543
Acta pharmacologica Sinica 2022 Jun;43(6):1534-1543
Asiatic acid alleviates ischemic myocardial injury in mice by modulating mitophagy- and glycophagy-based energy metabolism.
Qiu F, Yuan Y, Luo W, Gong YS, Zhang ZM, Liu ZM, Gao L
Acta pharmacologica Sinica 2022 Jun;43(6):1395-1407
Acta pharmacologica Sinica 2022 Jun;43(6):1395-1407
Ginkgo Biloba Extract Ameliorates Scopolamine-induced Memory Deficits via Rescuing Synaptic Damage.
Zhang GJ, Zheng D, Yu H, Luo XP, Wu W
Current medical science 2022 Jun;42(3):474-482
Current medical science 2022 Jun;42(3):474-482
Astrocytic Gap Junctions Contribute to Aberrant Neuronal Synchronization in a Mouse Model of MeCP2 Duplication Syndrome.
Xia S, Xu HT
Neuroscience bulletin 2022 Jun;38(6):591-606
Neuroscience bulletin 2022 Jun;38(6):591-606
Inhibition of FAM83D displays antitumor effects in glioblastoma via down-regulation of the AKT/Wnt/β-catenin pathway.
Wang J, Quan Y, Lv J, Gong S, Ren P
Environmental toxicology 2022 Jun;37(6):1343-1356
Environmental toxicology 2022 Jun;37(6):1343-1356
Naringin alleviates acetaminophen-induced acute liver injury by activating Nrf2 via CHAC2 upregulation.
Zhai X, Dai T, Chi Z, Zhao Z, Wu G, Yang S, Dong D
Environmental toxicology 2022 Jun;37(6):1332-1342
Environmental toxicology 2022 Jun;37(6):1332-1342
Identification and characterization of a special type of subnuclear structure: AGGF1-coated paraspeckles.
Zhao J, Xie W, Yang Z, Zhao M, Ke T, Xu C, Li H, Chen Q, Wang QK
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2022 Jun;36(6):e22366
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2022 Jun;36(6):e22366
Mitophagy induced by UMI-77 preserves mitochondrial fitness in renal tubular epithelial cells and alleviates renal fibrosis.
Jin L, Yu B, Liu G, Nie W, Wang J, Chen J, Xiao L, Xia H, Han F, Yang Y
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2022 Jun;36(6):e22342
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2022 Jun;36(6):e22342
Sclareol ameliorates hyperglycemia-induced renal injury through inhibiting the MAPK/NF-κB signaling pathway.
Han X, Zhang J, Zhou L, Wei J, Tu Y, Shi Q, Zhang Y, Ren J, Wang Y, Ying H, Liang G
Phytotherapy research : PTR 2022 Jun;36(6):2511-2523
Phytotherapy research : PTR 2022 Jun;36(6):2511-2523
MiR-153 downregulation alleviates PTSD-like behaviors and reduces cell apoptosis by upregulating the Sigma-1 receptor in the hippocampus of rats exposed to single-prolonged stress.
Chen YL, Tong L, Chen Y, Fu CH, Peng JB, Ji LL
Experimental neurology 2022 Jun;352:114034
Experimental neurology 2022 Jun;352:114034
Early environmental enrichment for autism spectrum disorder Fmr1 mice models has positive behavioral and molecular effects.
Chen YS, Zhang SM, Yue CX, Xiang P, Li JQ, Wei Z, Xu L, Zeng Y
Experimental neurology 2022 Jun;352:114033
Experimental neurology 2022 Jun;352:114033
TP53-inducible putative long noncoding RNAs encode functional polypeptides that suppress cell proliferation.
Xu W, Liu C, Deng B, Lin P, Sun Z, Liu A, Xuan J, Li Y, Zhou K, Zhang X, Huang Q, Zhou H, He Q, Li B, Qu L, Yang J
Genome research 2022 Jun;32(6):1026-1041
Genome research 2022 Jun;32(6):1026-1041
Berberine inhibits IFN-γ signaling pathway in DSS-induced ulcerative colitis.
Yang T, Ma X, Wang R, Liu H, Wei S, Jing M, Li H, Zhao Y
Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society 2022 Jun;30(6):764-778
Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society 2022 Jun;30(6):764-778
Loss of mitochondrial ATPase ATAD3A contributes to nonalcoholic fatty liver disease through accumulation of lipids and damaged mitochondria.
Chen L, Li Y, Sottas C, Lazaris A, Petrillo SK, Metrakos P, Li L, Ishida Y, Saito T, Garza S, Papadopoulos V
The Journal of biological chemistry 2022 Jun;298(6):102008
The Journal of biological chemistry 2022 Jun;298(6):102008
Myeloid-derived suppressor cells promote tumor growth and sorafenib resistance by inducing FGF1 upregulation and fibrosis.
Deng X, Li X, Guo X, Lu Y, Xie Y, Huang X, Lin J, Tan W, Wang C
Neoplasia (New York, N.Y.) 2022 Jun;28:100788
Neoplasia (New York, N.Y.) 2022 Jun;28:100788
A possible new activator of PI3K-Huayu Qutan Recipe alleviates mitochondrial apoptosis in obesity rats with acute myocardial infarction.
Tai H, Tong YJ, Yu R, Yu Y, Yao SC, Li LB, Liu Y, Cui XZ, Kuang JS, Meng XS, Jiang XL
Journal of cellular and molecular medicine 2022 Jun;26(12):3423-3445
Journal of cellular and molecular medicine 2022 Jun;26(12):3423-3445
RFTN1 facilitates gastric cancer progression by modulating AKT/p38 signaling pathways.
Deng C, Zhang L, Ma X, Cai S, Jia Y, Zhao L
Pathology, research and practice 2022 Jun;234:153902
Pathology, research and practice 2022 Jun;234:153902
Action of the Nrf2/ARE signaling pathway on oxidative stress in choroid plexus epithelial cells following lanthanum chloride treatment.
Sun J, Zhang Y, Yan L, Liu S, Wang W, Zhu Y, Wang W, Li S, He B, Wu L, Zhang L
Journal of inorganic biochemistry 2022 Jun;231:111792
Journal of inorganic biochemistry 2022 Jun;231:111792
hsa_circ_0000523/miR-let-7b/METTL3 axis regulates proliferation, apoptosis and metastasis in the HCT116 human colorectal cancer cell line.
Wang Y, Zhang B, Zhu Y, Zhang Y, Li L, Shen T, Liu H, Teng Y
Oncology letters 2022 Jun;23(6):186
Oncology letters 2022 Jun;23(6):186
AMG487 inhibits PRRSV replication and ameliorates lung injury in pig lung xenografts by down-regulating the expression of ANXA2.
Liu J, Yao L, Huang S, Wang B, Li L, Li L, Gu W, Xiao S, Liu G
Antiviral research 2022 Jun;202:105314
Antiviral research 2022 Jun;202:105314
Activation of CXCL13/CXCR5 axis aggravates experimental autoimmune cystitis and interstitial cystitis/bladder pain syndrome.
Zhao J, Chen S, Yang C, Zhou M, Yang T, Sun B, Zhu J, Zhang H, Lu Q, Li L, Yang Z, Song B, Shen W, Yi S, Dai S
Biochemical pharmacology 2022 Jun;200:115047
Biochemical pharmacology 2022 Jun;200:115047
The relationship between epigenetic age and the hallmarks of aging in human cells.
Kabacik S, Lowe D, Fransen L, Leonard M, Ang SL, Whiteman C, Corsi S, Cohen H, Felton S, Bali R, Horvath S, Raj K
Nature aging 2022 Jun;2(6):484-493
Nature aging 2022 Jun;2(6):484-493
FAIM regulates autophagy through glutaminolysis in lung adenocarcinoma.
Han T, Wang P, Wang Y, Xun W, Lei J, Wang T, Lu Z, Gan M, Zhang W, Yu B, Wang JB
Autophagy 2022 Jun;18(6):1416-1432
Autophagy 2022 Jun;18(6):1416-1432
Progenitor cells derived from gene-engineered human induced pluripotent stem cells as synthetic cancer cell alternatives for in vitro pharmacology.
Uhlmann C, Nickel AC, Picard D, Rossi A, Li G, Hildebrandt B, Brockerhoff G, Bendt F, Hübenthal U, Hewera M, Steiger HJ, Wieczorek D, Perrakis A, Zhang W, Remke M, Koch K, Tigges J, Croner RS, Fritsche E, Kahlert UD
Biotechnology journal 2022 Jun;17(6):e2100693
Biotechnology journal 2022 Jun;17(6):e2100693
Ror2-mediated cholesterol accumulation regulates autophagic activity within BCG-infected macrophages.
Zheng X, Li M, Chen Q, Ma B, Nie X, Liu Y, Yang Y, Xu J, Wang Y
Microbial pathogenesis 2022 Jun;167:105564
Microbial pathogenesis 2022 Jun;167:105564
Ligustrazine alleviates psoriasis-like inflammation through inhibiting TRAF6/c-JUN/NFκB signaling pathway in keratinocyte.
Jiang R, Xu J, Zhang Y, Liu J, Wang Y, Chen M, Chen X, Yin M
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Jun;150:113010
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Jun;150:113010
Dexmedetomidine attenuates perioperative neurocognitive disorders by suppressing hippocampal neuroinflammation and HMGB1/RAGE/NF-κB signaling pathway.
Wang J, Xin Y, Chu T, Liu C, Xu A
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Jun;150:113006
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Jun;150:113006
Obeticholic acid inhibits hepatic fatty acid uptake independent of FXR in mouse.
Lin C, Yu B, Liu X, Chen L, Zhang Z, Ye W, Zhong H, Bai W, Yang Y, Nie B
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Jun;150:112984
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Jun;150:112984
Novel RARS2 Variants: Updating the Diagnosis and Pathogenesis of Pontocerebellar Hypoplasia Type 6.
Zhang Y, Yu Y, Zhao X, Xu Y, Chen L, Li N, Yao R, Wang J, Yu T
Pediatric neurology 2022 Jun;131:30-41
Pediatric neurology 2022 Jun;131:30-41
ZNF677 suppresses renal cell carcinoma progression through N6-methyladenosine and transcriptional repression of CDKN3.
Li A, Cao C, Gan Y, Wang X, Wu T, Zhang Q, Liu Y, Yao L, Zhang Q
Clinical and translational medicine 2022 Jun;12(6):e906
Clinical and translational medicine 2022 Jun;12(6):e906
Discovery of oridonin as a novel agonist for BRS-3.
Zhu Y, Wu L, Zhao Y, Wang Z, Lu J, Yu Y, Xiao H, Zhang Y
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Jun;100:154085
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Jun;100:154085
Beneficial effects of aloperine on inflammation and oxidative stress by suppressing necroptosis in lipopolysaccharide-induced acute lung injury mouse model.
Cui YR, Qu F, Zhong WJ, Yang HH, Zeng J, Huang JH, Liu J, Zhang MY, Zhou Y, Guan CX
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Jun;100:154074
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Jun;100:154074
Nanoparticle delivery of miR-21-3p sensitizes melanoma to anti-PD-1 immunotherapy by promoting ferroptosis.
Guo W, Wu Z, Chen J, Guo S, You W, Wang S, Ma J, Wang H, Wang X, Wang H, Ma J, Yang Y, Tian Y, Shi Q, Gao T, Yi X, Li C
Journal for immunotherapy of cancer 2022 Jun;10(6)
Journal for immunotherapy of cancer 2022 Jun;10(6)
Bioinformatics analysis combined with experiments to verify potential autophagy genes in wound healing.
Wu YF, Fang DL, Wei J
Annals of translational medicine 2022 Jun;10(12):680
Annals of translational medicine 2022 Jun;10(12):680
Sorafenib inhibits LPS-induced inflammation by regulating Lyn-MAPK-NF-kB/AP-1 pathway and TLR4 expression.
Li X, Xu M, Shen J, Li Y, Lin S, Zhu M, Pang Q, Tan X, Tang J
Cell death discovery 2022 Jun 9;8(1):281
Cell death discovery 2022 Jun 9;8(1):281
Novel Sphingosine Kinase 1 Inhibitor Suppresses Growth of Solid Tumor and Inhibits the Lung Metastasis of Triple-Negative Breast Cancer.
Zhang S, Chen X, Wu C, Xu H, Xie X, Feng M, Hu S, Bai H, Gao F, Tong L, Ding J, Liu H, Xie Z, Wang J
Journal of medicinal chemistry 2022 Jun 9;65(11):7697-7716
Journal of medicinal chemistry 2022 Jun 9;65(11):7697-7716
A novel ALG10/TGF-β positive regulatory loop contributes to the stemness of colorectal cancer.
Xu X, Wang H, Li X, Duan X, Wang Y
Aging 2022 Jun 9;14(11):4858-4873
Aging 2022 Jun 9;14(11):4858-4873
Novel Thermosensitive Hydrogel Promotes Spinal Cord Repair by Regulating Mitochondrial Function.
Li Y, Yang L, Hu F, Xu J, Ye J, Liu S, Wang L, Zhuo M, Ran B, Zhang H, Ye J, Xiao J
ACS applied materials & interfaces 2022 Jun 8;14(22):25155-25172
ACS applied materials & interfaces 2022 Jun 8;14(22):25155-25172
Occlusal Disharmony-A Potential Factor Promoting Depression in a Rat Model.
Zhang S, Wu L, Zhang M, He K, Wang X, Lin Y, Li S, Chen J
Brain sciences 2022 Jun 7;12(6)
Brain sciences 2022 Jun 7;12(6)
Adrenomedullin Improves Cardiac Remodeling and Function in Obese Rats with Hypertension.
Qian P, Wang Q, Wang FZ, Dai HB, Wang HY, Gao Q, Zhou H, Zhou YB
Pharmaceuticals (Basel, Switzerland) 2022 Jun 6;15(6)
Pharmaceuticals (Basel, Switzerland) 2022 Jun 6;15(6)
Synthesis and structure-activity relationship study of a potent MHO7 analogue as potential anti-triple negative breast cancer agent.
Liang JJ, Yu WL, Yang L, Qin KM, Yin YP, Li D, Ni YH, Yan JJ, Zhong YX, Deng ZX, Hong K
European journal of medicinal chemistry 2022 Jun 5;236:114313
European journal of medicinal chemistry 2022 Jun 5;236:114313
A pH-Dependent rhodamine fluorophore with antiproliferative activity of bladder cancer in Vitro/Vivo and apoptosis mechanism.
Lu D, Yang T, Tang N, Li C, Song Y, Wang L, Wong WY, Yin SF, Xing Y, Kambe N, Qiu R
European journal of medicinal chemistry 2022 Jun 5;236:114293
European journal of medicinal chemistry 2022 Jun 5;236:114293
SGK1 in Schwann cells is a potential molecular switch involved in axonal and glial regeneration during peripheral nerve injury.
Okura A, Inoue K, Sakuma E, Takase H, Ueki T, Mase M
Biochemical and biophysical research communications 2022 Jun 4;607:158-165
Biochemical and biophysical research communications 2022 Jun 4;607:158-165
Insulin alleviates LPS-induced ARDS via inhibiting CUL4B-mediated proteasomal degradation and restoring expression level of Na,K-ATPase α1 subunit through elevating HCF-1.
Huang XT, Zheng Y, Long G, Peng WT, Wan QQ
Biochemical and biophysical research communications 2022 Jun 30;611:60-67
Biochemical and biophysical research communications 2022 Jun 30;611:60-67
Cumulative autophagy insufficiency in mice leads to progression of β-cell failure.
Suzuki L, Miyatsuka T, Himuro M, Wakabayashi Y, Osonoi S, Miura M, Katahira T, Fujitani Y, Iida H, Mizukami H, Nishida Y, Watada H
Biochemical and biophysical research communications 2022 Jun 30;611:38-45
Biochemical and biophysical research communications 2022 Jun 30;611:38-45
STING activation promotes inflammatory response and delays skin wound healing in diabetic mice.
Feng Z, Zang C, Zhang L, Yin S, Zhuang Q, Wang X
Biochemical and biophysical research communications 2022 Jun 30;611:126-131
Biochemical and biophysical research communications 2022 Jun 30;611:126-131
MicroRNA-223-3p promotes pyroptosis of cardiomyocyte and release of inflammasome factors via downregulating the expression level of SPI1 (PU.1).
Zhao S, Tan Y, Qin J, Xu H, Liu L, Wan H, Zhang C, Fan W, Qu S
Toxicology 2022 Jun 30;476:153252
Toxicology 2022 Jun 30;476:153252
Upregulation of CCT3 predicts poor prognosis and promotes cell proliferation via inhibition of ferroptosis and activation of AKT signaling in lung adenocarcinoma.
Wang K, He J, Tu C, Xu H, Zhang X, Lv Y, Song C
BMC molecular and cell biology 2022 Jun 30;23(1):25
BMC molecular and cell biology 2022 Jun 30;23(1):25
CircEZH2/miR-133b/IGF2BP2 aggravates colorectal cancer progression via enhancing the stability of m(6)A-modified CREB1 mRNA.
Yao B, Zhang Q, Yang Z, An F, Nie H, Wang H, Yang C, Sun J, Chen K, Zhou J, Bai B, Gu S, Zhao W, Zhan Q
Molecular cancer 2022 Jun 30;21(1):140
Molecular cancer 2022 Jun 30;21(1):140
Trans-cellular tunnels induced by the fungal pathogen Candida albicans facilitate invasion through successive epithelial cells without host damage.
Lachat J, Pascault A, Thibaut D, Le Borgne R, Verbavatz JM, Weiner A
Nature communications 2022 Jun 30;13(1):3781
Nature communications 2022 Jun 30;13(1):3781
Preparation of Recombinant Human Collagen III Protein Hydrogels with Sustained Release of Extracellular Vesicles for Skin Wound Healing.
Xu L, Liu Y, Tang L, Xiao H, Yang Z, Wang S
International journal of molecular sciences 2022 Jun 3;23(11)
International journal of molecular sciences 2022 Jun 3;23(11)
A Class I HDAC Inhibitor Rescues Synaptic Damage and Neuron Loss in APP-Transfected Cells and APP/PS1 Mice through the GRIP1/AMPA Pathway.
Han Y, Chen L, Liu J, Chen J, Wang C, Guo Y, Yu X, Zhang C, Chu H, Ma H
Molecules (Basel, Switzerland) 2022 Jun 29;27(13)
Molecules (Basel, Switzerland) 2022 Jun 29;27(13)
Gut Microbiota Mediates the Protective Effects of Traditional Chinese Medicine Formula Qiong-Yu-Gao against Cisplatin-Induced Acute Kidney Injury.
Zou YT, Zhou J, Zhu JH, Wu CY, Shen H, Zhang W, Zhou SS, Xu JD, Mao Q, Zhang YQ, Long F, Li SL
Microbiology spectrum 2022 Jun 29;10(3):e0075922
Microbiology spectrum 2022 Jun 29;10(3):e0075922
Khasianine ameliorates psoriasis-like skin inflammation and represses TNF-α/NF-κB axis mediated transactivation of IL-17A and IL-33 in keratinocytes.
Yang Y, Zhang Y, Chen X, Su Z, Deng Y, Zhao Q
Journal of ethnopharmacology 2022 Jun 28;292:115124
Journal of ethnopharmacology 2022 Jun 28;292:115124
A volatile from the skin microbiota of flavivirus-infected hosts promotes mosquito attractiveness.
Zhang H, Zhu Y, Liu Z, Peng Y, Peng W, Tong L, Wang J, Liu Q, Wang P, Cheng G
Cell 2022 Jun 28;
Cell 2022 Jun 28;
Astrocyte reactivation in medial prefrontal cortex contributes to obesity-promoted depressive-like behaviors.
Yu G, Cao F, Hou T, Cheng Y, Jia B, Yu L, Chen W, Xu Y, Chen M, Wang Y
Journal of neuroinflammation 2022 Jun 27;19(1):166
Journal of neuroinflammation 2022 Jun 27;19(1):166
The 22q11.2 region regulates presynaptic gene-products linked to schizophrenia.
Nehme R, Pietiläinen O, Artomov M, Tegtmeyer M, Valakh V, Lehtonen L, Bell C, Singh T, Trehan A, Sherwood J, Manning D, Peirent E, Malik R, Guss EJ, Hawes D, Beccard A, Bara AM, Hazelbaker DZ, Zuccaro E, Genovese G, Loboda AA, Neumann A, Lilliehook C, Kuismin O, Hamalainen E, Kurki M, Hultman CM, Kähler AK, Paulo JA, Ganna A, Madison J, Cohen B, McPhie D, Adolfsson R, Perlis R, Dolmetsch R, Farhi S, McCarroll S, Hyman S, Neale B, Barrett LE, Harper W, Palotie A, Daly M, Eggan K
Nature communications 2022 Jun 27;13(1):3690
Nature communications 2022 Jun 27;13(1):3690
Hydroxychloroquine alleviates renal interstitial fibrosis by inhibiting the PI3K/Akt signaling pathway.
Li D, Yu K, Feng F, Zhang Y, Bai F, Zhang Y, Sun N, Fan J, Liu L, Yang H, Yang X
Biochemical and biophysical research communications 2022 Jun 25;610:154-161
Biochemical and biophysical research communications 2022 Jun 25;610:154-161
An N-glycoproteomic site-mapping analysis reveals glycoprotein alterations in esophageal squamous cell carcinoma.
Gao Y, Shen L, Dong T, Yang X, Cui H, Guo Y, Ma Y, Kong P, Cheng X, Zhang L, Cui Y
Journal of translational medicine 2022 Jun 25;20(1):285
Journal of translational medicine 2022 Jun 25;20(1):285
LncRNA PEG11as silencing sponges miR-874-3p to alleviate cerebral ischemia stroke via regulating autophagy in vivo and in vitro.
Hu X, Ma F, Cheng Z, Zeng S, Shen R, Li X, Hu J, Jin Z, Cheng J
Aging 2022 Jun 24;14(12):5177-5194
Aging 2022 Jun 24;14(12):5177-5194
G Protein Subunit β1 Facilitates Influenza A Virus Replication by Promoting the Nuclear Import of PB2.
Zheng H, Ma L, Gui R, Lin X, Ke X, Jian X, Ye C, Chen Q
Journal of virology 2022 Jun 22;96(12):e0049422
Journal of virology 2022 Jun 22;96(12):e0049422
Establishment of a Novel Cell Surface Display Platform Based on Natural "Chitosan Beads" of Yeast Spores.
Li Z, Li W, Wang Y, Chen Z, Nakanishi H, Xu X, Gao XD
Journal of agricultural and food chemistry 2022 Jun 22;70(24):7479-7489
Journal of agricultural and food chemistry 2022 Jun 22;70(24):7479-7489
Pathogenic SLC25A26 variants impair SAH transport activity causing mitochondrial disease.
Schober FA, Tang JX, Sergeant K, Moedas MF, Zierz CM, Moore D, Smith C, Lewis D, Guha N, Hopton S, Falkous G, Lam A, Pyle A, Poulton J, Gorman GS, Taylor RW, Freyer C, Wredenberg A
Human molecular genetics 2022 Jun 22;31(12):2049-2062
Human molecular genetics 2022 Jun 22;31(12):2049-2062
Abnormal activation of Yap/Taz contributes to the pathogenesis of tuberous sclerosis complex.
Terry BK, Park R, Cho SH, Crino PB, Kim S
Human molecular genetics 2022 Jun 22;31(12):1979-1996
Human molecular genetics 2022 Jun 22;31(12):1979-1996
Upregulated GATA3/miR205-5p Axis Inhibits MFNG Transcription and Reduces the Malignancy of Triple-Negative Breast Cancer.
Mugisha S, Di X, Wen D, Zhao Y, Wu X, Zhang S, Jiang H
Cancers 2022 Jun 22;14(13)
Cancers 2022 Jun 22;14(13)
Treadmill training improves respiratory function in rats after spinal cord injury by inhibiting the HMGB1/TLR-4/NF-κB signaling pathway.
Tang D, Wang X, Chen Y, Yang X, Hu S, Song N, Wang J, Cheng J, Wu S
Neuroscience letters 2022 Jun 21;782:136686
Neuroscience letters 2022 Jun 21;782:136686
Oxidative stress from DGAT1 oncoprotein inhibition in melanoma suppresses tumor growth when ROS defenses are also breached.
Wilcock DJ, Badrock AP, Wong CW, Owen R, Guerin M, Southam AD, Johnston H, Telfer BA, Fullwood P, Watson J, Ferguson H, Ferguson J, Lloyd GR, Jankevics A, Dunn WB, Wellbrock C, Lorigan P, Ceol C, Francavilla C, Smith MP, Hurlstone AFL
Cell reports 2022 Jun 21;39(12):110995
Cell reports 2022 Jun 21;39(12):110995
(-)-α-Bisabolol Alleviates Atopic Dermatitis by Inhibiting MAPK and NF-κB Signaling in Mast Cell.
Li G, Wu H, Sun L, Cheng K, Lv Z, Chen K, Qian F, Li Y
Molecules (Basel, Switzerland) 2022 Jun 21;27(13)
Molecules (Basel, Switzerland) 2022 Jun 21;27(13)
Adlay Seed (Coix lacryma-jobi L. var. Ma-yuen Stapf.) Ethanolic Extract Fractions and Subfractions Induce Cell Cycle Arrest and Apoptosis in Human Breast and Cervical Cancer Cell Lines.
Chiang YF, Chung CP, Lin JH, Chiang W, Chen HY, Ali M, Shih YH, Wang KL, Huang TC, Chang HY, Lin LC, Shieh TM, Hsia SM
Molecules (Basel, Switzerland) 2022 Jun 21;27(13)
Molecules (Basel, Switzerland) 2022 Jun 21;27(13)
Apelin alleviated neuroinflammation and promoted endogenous neural stem cell proliferation and differentiation after spinal cord injury in rats.
Liu Q, Zhou S, Wang X, Gu C, Guo Q, Li X, Zhang C, Zhang N, Zhang L, Huang F
Journal of neuroinflammation 2022 Jun 20;19(1):160
Journal of neuroinflammation 2022 Jun 20;19(1):160
Complement C3a activates astrocytes to promote medulloblastoma progression through TNF-α.
Gong B, Guo D, Zheng C, Ma Z, Zhang J, Qu Y, Li X, Li G, Zhang L, Wang Y
Journal of neuroinflammation 2022 Jun 20;19(1):159
Journal of neuroinflammation 2022 Jun 20;19(1):159
The PRMT5-LSD1 axis confers Slug dual transcriptional activities and promotes breast cancer progression.
Zhang J, Fan X, Zhou Y, Chen L, Rao H
Journal of experimental & clinical cancer research : CR 2022 Jun 2;41(1):191
Journal of experimental & clinical cancer research : CR 2022 Jun 2;41(1):191
LINC00094/miR-19a-3p/CYP19A1 axis affects the sensitivity of ER positive breast cancer cells to Letrozole through EMT pathway.
Xiang Y, Liu H, Hu H, Li LW, Zong QB, Wu TW, Li XY, Fang SQ, Liu YW, Zhan Y, Wang H, Lu ZX
Aging 2022 Jun 2;14(11):4755-4768
Aging 2022 Jun 2;14(11):4755-4768
Cryopreservation Competence of Chicken Oocytes as a Model of Endangered Wild Birds: Effects of Storage Time and Temperature on the Ovarian Follicle Survival.
Fujihara M, Shiraishi JI, Onuma M, Ohta Y, Inoue-Murayama M
Animals : an open access journal from MDPI 2022 Jun 2;12(11)
Animals : an open access journal from MDPI 2022 Jun 2;12(11)
Enhanced autophagy promotes radiosensitivity by mediating Sirt1 downregulation in RM-1 prostate cancer cells.
Wang KX, Yan C, Yang X, Zhu PY, Cui WW, Ye C, Hu K, Lan T, Huang LY, Wang W, Ma P, Qi SH, Gu B, Luo L
Biochemical and biophysical research communications 2022 Jun 18;609:84-92
Biochemical and biophysical research communications 2022 Jun 18;609:84-92
The mechanism of the WNT5A and FZD4 receptor mediated WNT/β-catenin pathway in the degeneration of ALS spinal cord motor neurons.
Jiang X, Liu J, Guan Y, Zhao Z, Meng F, Wang X, Gao X, Zhou F, Chen Y, Wang X
Biochemical and biophysical research communications 2022 Jun 18;609:23-30
Biochemical and biophysical research communications 2022 Jun 18;609:23-30
Grpel2 alleviates myocardial ischemia/reperfusion injury by inhibiting MCU-mediated mitochondrial calcium overload.
Yang R, Zhang X, Xing P, Zhang S, Zhang F, Wang J, Yu J, Zhu X, Chang P
Biochemical and biophysical research communications 2022 Jun 18;609:169-175
Biochemical and biophysical research communications 2022 Jun 18;609:169-175
Protocol to induce and assess cGAS-STING pathway activation in vitro.
Chamma H, Guha S, Laguette N, Vila IK
STAR protocols 2022 Jun 17;3(2):101384
STAR protocols 2022 Jun 17;3(2):101384
Isolation of five different primary cell types from a single sample of human skin.
Kabacik S, Lowe D, Cohen H, Felton S, Spitzer J, Raj K
STAR protocols 2022 Jun 17;3(2):101378
STAR protocols 2022 Jun 17;3(2):101378
Diminished Rbfox1 increases vascular constriction by dynamically regulating alternative splicing of CaV1.2 calcium channel in hypertension.
Song M, Hou W, Mustafa AU, Li P, Lei J, Zhou Y, Ji L, Sun Y, Zhou H, Xu Y, Wang J
Clinical science (London, England : 1979) 2022 Jun 17;136(11):803-817
Clinical science (London, England : 1979) 2022 Jun 17;136(11):803-817
A long-term anti-inflammation markedly alleviated high-fat diet-induced obesity by repeated administrations of overexpressing IL10 human umbilical cord-derived mesenchymal stromal cells.
Wang L, Gao T, Li Y, Xie Y, Zeng S, Tai C, Feng Y, Shen P, Wang B
Stem cell research & therapy 2022 Jun 17;13(1):259
Stem cell research & therapy 2022 Jun 17;13(1):259
Coxiella burnetii Plasmid Effector B Promotes LC3-II Accumulation and Contributes To Bacterial Virulence in a SCID Mouse Model.
Fu M, Zhang J, Zhao M, Zhang S, Dai L, Ouyang X, Yu Y, Wen B, Zhou D, Sun Y, Jiao J, Xiong X
Infection and immunity 2022 Jun 16;90(6):e0001622
Infection and immunity 2022 Jun 16;90(6):e0001622
Redirecting anti-Vaccinia virus T cell immunity for cancer treatment by AAV-mediated delivery of the VV B8R gene.
Cao D, Song Q, Li J, Chard Dunmall LS, Jiang Y, Qin B, Wang J, Guo H, Cheng Z, Wang Z, Lemoine NR, Lu S, Wang Y
Molecular therapy oncolytics 2022 Jun 16;25:264-275
Molecular therapy oncolytics 2022 Jun 16;25:264-275
A novel phosphodiesterase 9A inhibitor LW33 protects against ischemic stroke through the cGMP/PKG/CREB pathway.
You JY, Liu XW, Bao YX, Shen ZN, Wang Q, He GY, Lu J, Zhang JG, Chen JW, Liu PQ
European journal of pharmacology 2022 Jun 15;925:174987
European journal of pharmacology 2022 Jun 15;925:174987
Neurotoxicity and gene expression alterations in zebrafish larvae in response to manganese exposure.
Xu Y, Peng T, Xiang Y, Liao G, Zou F, Meng X
The Science of the total environment 2022 Jun 15;825:153778
The Science of the total environment 2022 Jun 15;825:153778
FAM98A promotes resistance to 5-fluorouracil in colorectal cancer by suppressing ferroptosis.
He Z, Yang J, Sui C, Zhang P, Wang T, Mou T, Sun K, Wang Y, Xu Z, Li G, Deng H, Shi J, Zhuang B
Archives of biochemistry and biophysics 2022 Jun 15;722:109216
Archives of biochemistry and biophysics 2022 Jun 15;722:109216
Elevated latent transforming growth factor beta binding protein 2 in endometriosis promotes endometrial stromal cell invasion and proliferation via the NF-kB signaling pathway.
Wang D, Zhang Y, Cui L, Yang Q, Wang J
Molecular and cellular endocrinology 2022 Jun 15;550:111647
Molecular and cellular endocrinology 2022 Jun 15;550:111647
TRIM62 silencing represses the proliferation and invasion and increases the chemosensitivity of hepatocellular carcinoma cells by affecting the NF-κB pathway.
Fan W, Liu X, Ren D
Toxicology and applied pharmacology 2022 Jun 15;445:116035
Toxicology and applied pharmacology 2022 Jun 15;445:116035
Deubiquitinating enzyme PSMD14 facilitates gastric carcinogenesis through stabilizing PTBP1.
Li J, Li Y, Xu F, Sun B, Yang L, Wang H
Experimental cell research 2022 Jun 15;415(2):113148
Experimental cell research 2022 Jun 15;415(2):113148
Upregulation of hepatic CD36 via glucocorticoid receptor activation contributes to dexamethasone-induced liver lipid metabolism disorder in mice.
Chen M, Bai M, Yi Y, Lu S, Luo J, Li P, Zhang H, Jiang H, Zhou H
Toxicology letters 2022 Jun 15;363:1-10
Toxicology letters 2022 Jun 15;363:1-10
JNK and Jag1/Notch2 co-regulate CXCL16 to facilitate cypermethrin-induced kidney damage.
Liu C, Wu M, Qu J, Huang X, Zeng Q, Ha M
Ecotoxicology and environmental safety 2022 Jun 15;238:113582
Ecotoxicology and environmental safety 2022 Jun 15;238:113582
The IL-33/ST2 Axis Promotes Primary Sjögren's Syndrome by Enhancing Salivary Epithelial Cell Activation and Type 1 Immune Response.
Dong Y, Ming B, Gao R, Mo Q, Wu X, Zheng F, Zhong J, Dong L
Journal of immunology (Baltimore, Md. : 1950) 2022 Jun 15;208(12):2652-2662
Journal of immunology (Baltimore, Md. : 1950) 2022 Jun 15;208(12):2652-2662
Exosomal mitochondrial tRNAs and miRNAs as potential predictors of inflammation in renal proximal tubular epithelial cells.
Ranches G, Zeidler M, Kessler R, Hoelzl M, Hess MW, Vosper J, Perco P, Schramek H, Kummer KK, Kress M, Krogsdam A, Rudnicki M, Mayer G, Huettenhofer A
Molecular therapy. Nucleic acids 2022 Jun 14;28:794-813
Molecular therapy. Nucleic acids 2022 Jun 14;28:794-813
TAZ ameliorates the microglia-mediated inflammatory response via the Nrf2-ROS-NF-κB pathway.
Huang JC, Yue ZP, Yu HF, Yang ZQ, Wang YS, Guo B
Molecular therapy. Nucleic acids 2022 Jun 14;28:435-449
Molecular therapy. Nucleic acids 2022 Jun 14;28:435-449
Thrombospondin-2 acts as a bridge between tumor extracellular matrix and immune infiltration in pancreatic and stomach adenocarcinomas: an integrative pan-cancer analysis.
Liao X, Wang W, Yu B, Tan S
Cancer cell international 2022 Jun 14;22(1):213
Cancer cell international 2022 Jun 14;22(1):213
Dopamine-derived nanoparticles for the protection of irradiation-induced intestinal injury by maintaining intestinal homeostasis.
Jia S, Dong S, Liu H, Yu H, Chen Z, Wang S, Li W, Peng R, Li F, Jiang Q, Liu J
Biomaterials science 2022 Jun 14;10(12):3309-3322
Biomaterials science 2022 Jun 14;10(12):3309-3322
RING finger 138 deregulation distorts NF-кB signaling and facilities colitis switch to aggressive malignancy.
Lu Y, Huang R, Ying J, Li X, Jiao T, Guo L, Zhou H, Wang H, Tuersuntuoheti A, Liu J, Chen Q, Wang Y, Su L, Guo C, Xu F, Wang Z, Lu Y, Li K, Liang J, Huang Z, Chen X, Yao J, Hu H, Cheng X, Wan Y, Chen X, Zhang N, Miao S, Cai J, Wang L, Liu C, Song W, Zhao H
Signal transduction and targeted therapy 2022 Jun 13;7(1):185
Signal transduction and targeted therapy 2022 Jun 13;7(1):185
Fast detection, a precise and sensitive diagnostic agent for breast cancer.
Wu Q, Yuan C, Liu N, Shu J, Wang J, Qian J, Zeng L, Zhang H, Wang X, Mei W
Journal of experimental & clinical cancer research : CR 2022 Jun 13;41(1):201
Journal of experimental & clinical cancer research : CR 2022 Jun 13;41(1):201
A Cross-Tissue Investigation of Molecular Targets and Physiological Functions of Nsun6 Using Knockout Mice.
Wang W, Huang H, Jiang H, Tian C, Tang Y, Gan D, Wen X, Song Z, He Y, Ou X, Fang L
International journal of molecular sciences 2022 Jun 13;23(12)
International journal of molecular sciences 2022 Jun 13;23(12)
The effect of Ma-Xin-Gan-Shi decoction on asthma exacerbated by respiratory syncytial virus through regulating TRPV1 channel.
Li M, Fan X, Zhou L, Jiang M, Shang E
Journal of ethnopharmacology 2022 Jun 12;291:115157
Journal of ethnopharmacology 2022 Jun 12;291:115157
Phenazine derivatives attenuate the stemness of breast cancer cells through triggering ferroptosis.
Yang Y, Lu Y, Zhang C, Guo Q, Zhang W, Wang T, Xia Z, Liu J, Cheng X, Xi T, Jiang F, Zheng L
Cellular and molecular life sciences : CMLS 2022 Jun 11;79(7):360
Cellular and molecular life sciences : CMLS 2022 Jun 11;79(7):360
Acute cold stress induces transient MuRF1 upregulation in the skeletal muscle of zebrafish.
Tamai S, Fujita SI, Komine R, Kanki Y, Aoki K, Watanabe K, Takekoshi K, Sugasawa T
Biochemical and biophysical research communications 2022 Jun 11;608:59-65
Biochemical and biophysical research communications 2022 Jun 11;608:59-65
CUX1 promotes epithelial-mesenchymal transition (EMT) in renal fibrosis of UUO model by targeting MMP7.
Teng S, Liu G, Li L, Ou J, Yu Y
Biochemical and biophysical research communications 2022 Jun 11;608:128-134
Biochemical and biophysical research communications 2022 Jun 11;608:128-134
ITRAQ-based quantitative proteomic analysis reveals that VPS35 promotes the expression of MCM2-7 genes in HeLa cells.
Hong X, Wang T, Du J, Hong Y, Yang CP, Xiao W, Li Y, Wang M, Sun H, Deng ZH
Scientific reports 2022 Jun 11;12(1):9700
Scientific reports 2022 Jun 11;12(1):9700
Platelet-Membrane-Encapsulated Carvedilol with Improved Targeting Ability for Relieving Myocardial Ischemia-Reperfusion Injury.
Zhou T, Yang X, Wang T, Xu M, Huang Z, Yu R, Jiang Y, Zhou Y, Shi J
Membranes 2022 Jun 10;12(6)
Membranes 2022 Jun 10;12(6)
Chronic clomipramine treatment increases hippocampal volume in rats exposed to chronic unpredictable mild stress.
Zhang S, Hu J, Liu G, Wu H, Li M, Shi C, Liu Q, Li W
Translational psychiatry 2022 Jun 10;12(1):245
Translational psychiatry 2022 Jun 10;12(1):245
Selenium Status in Diet Affects Nephrotoxicity Induced by Cisplatin in Mice.
Liu S, Wen X, Huang Q, Zhu M, Lu J
Antioxidants (Basel, Switzerland) 2022 Jun 10;11(6)
Antioxidants (Basel, Switzerland) 2022 Jun 10;11(6)
Identification of differentially expressed miRNAs derived from serum exosomes associated with gastric cancer by microarray analysis.
Ren ZJ, Zhao Y, Wang G, Miao LL, Zhang ZC, Ma L, Teng MZ, Li YM
Clinica chimica acta; international journal of clinical chemistry 2022 Jun 1;531:25-35
Clinica chimica acta; international journal of clinical chemistry 2022 Jun 1;531:25-35
IL-6 promotes chemoresistance via upregulating CD36 mediated fatty acids uptake in acute myeloid leukemia.
Zhang Y, Guo H, Zhang Z, Lu W, Zhu J, Shi J
Experimental cell research 2022 Jun 1;415(1):113112
Experimental cell research 2022 Jun 1;415(1):113112
Transcriptomics analysis and benchmark concentration estimating-based in vitro test with IOSE80 cells to unveil the mode of action for female reproductive toxicity of bisphenol A at human-relevant levels.
Li X, Ni M, Xiong W, Tian L, Yang Z, Zhang L, Chen J
Ecotoxicology and environmental safety 2022 Jun 1;237:113523
Ecotoxicology and environmental safety 2022 Jun 1;237:113523
Pivotal roles of ELONGATED HYPOCOTYL5 in regulation of plant development and fruit metabolism in tomato.
Zhang C, Wu Y, Liu X, Zhang J, Li X, Lin L, Yin R
Plant physiology 2022 Jun 1;189(2):527-540
Plant physiology 2022 Jun 1;189(2):527-540
Ppp4r3a deficiency leads to depression-like behaviors in mice by modulating the synthesis of synaptic proteins.
Gao F, Liu A, Qi X, Wang M, Chen X, Wei S, Gao S, Sun Y, Sun P, Li X, Sun W, Li J, Liu Q
Disease models & mechanisms 2022 Jun 1;15(6)
Disease models & mechanisms 2022 Jun 1;15(6)
Exogenous Otx2 protects midbrain dopaminergic neurons from MPP(+) by interacting with ATP5a1 and promoting ATP synthesis.
Xue J, Li Y, Qi Y, Zhang Z, Tang X
Neurotoxicology 2022 Jul;91:211-217
Neurotoxicology 2022 Jul;91:211-217
SNAT2/SLC38A2 Confers the Stemness of Gastric Cancer Cells via Regulating Glutamine Level.
Nie K, Cai M
Digestive diseases and sciences 2022 Jul;67(7):2948-2956
Digestive diseases and sciences 2022 Jul;67(7):2948-2956
Attenuation by HSP90 inhibitors of EGF-elicited migration of osteoblasts: involvement of p44/p42 MAP kinase.
Kuroyanagi G, Kawabata T, Tokuda H, Fujita K, Matsushima-Nishiwaki R, Sakai G, Tachi J, Hioki T, Kim W, Iida H, Otsuka T, Kozawa O
Connective tissue research 2022 Jul;63(4):359-369
Connective tissue research 2022 Jul;63(4):359-369
Inhibition of nuclear deacetylase Sirtuin-1 induces mitochondrial acetylation and calcium overload leading to cell death.
Sun Y, Yang YM, Hu YY, Ouyang L, Sun ZH, Yin XF, Li N, He QY, Wang Y
Redox biology 2022 Jul;53:102334
Redox biology 2022 Jul;53:102334
Pharmacological activation of estrogenic receptor G protein-coupled receptor 30 attenuates angiotensin II-induced atrial fibrosis in ovariectomized mice by modulating TGF-β1/smad pathway.
Liu D, Zhan Y, Ono K, Yin Y, Wang L, Wei M, Ji L, Liu M, Liu G, Zhou X, Zheng M
Molecular biology reports 2022 Jul;49(7):6341-6355
Molecular biology reports 2022 Jul;49(7):6341-6355
Comprehensive analysis of the expression and prognosis of YPEL family members in clear cell renal cell cancer.
Wang L, Zhang Z, Zhou X, Wu J, Hong Z
Oncology reports 2022 Jul;48(1)
Oncology reports 2022 Jul;48(1)
Ophiopogonin D'-induced mitophagy and mitochondrial damage are associated with dysregulation of the PINK1/Parkin signaling pathway in AC16 cells.
Lei S, Feng Y, Huang P, Chen B, Bao K, Wu Q, Zhang H, Huang X
Toxicology 2022 Jul;477:153275
Toxicology 2022 Jul;477:153275
In utero hypoxia attenuated acetylcholine-mediated vasodilatation via CHRM3/p-NOS3 in fetal sheep MCA: role of ROS/ERK1/2.
He Y, Su H, Li N, Zhang Y, Zhang P, Zhang Y, Ye Y, Zhang Y, Tang J, Xu Z
Hypertension research : official journal of the Japanese Society of Hypertension 2022 Jul;45(7):1168-1182
Hypertension research : official journal of the Japanese Society of Hypertension 2022 Jul;45(7):1168-1182
FOXM1 Promotes Malignant Proliferation of Esophageal Squamous Cell Carcinoma Through Transcriptional Activating CDC6.
Chen X, Chen J, Yu X, Lin G, Chen T
DNA and cell biology 2022 Jul;41(7):671-682
DNA and cell biology 2022 Jul;41(7):671-682
HAO1-mediated oxalate metabolism promotes lung pre-metastatic niche formation by inducing neutrophil extracellular traps.
Zeng Z, Xu S, Wang F, Peng X, Zhang W, Zhan Y, Ding Y, Liu Z, Liang L
Oncogene 2022 Jul;41(29):3719-3731
Oncogene 2022 Jul;41(29):3719-3731
2-undecanone protects against fine particles-induced heart inflammation via modulating Nrf2/HO-1 and NF-κB pathways.
Jiao Y, Wang S, Jiang L, Sun X, Li J, Liu X, Yao X, Zhang C, Wang N, Deng H, Yang G
Environmental toxicology 2022 Jul;37(7):1642-1652
Environmental toxicology 2022 Jul;37(7):1642-1652
MicroRNA profiling reveals miR-145-5p inhibits goat myoblast differentiation by targeting the coding domain sequence of USP13.
Zhang Z, Deng K, Kang Z, Wang F, Fan Y
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2022 Jul;36(7):e22370
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2022 Jul;36(7):e22370
Trilobatin promotes angiogenesis after cerebral ischemia-reperfusion injury via SIRT7/VEGFA signaling pathway in rats.
Huang F, Luo L, Wu Y, Xia D, Xu F, Gao J, Shi J, Gong Q
Phytotherapy research : PTR 2022 Jul;36(7):2940-2951
Phytotherapy research : PTR 2022 Jul;36(7):2940-2951
Retraction Note: Long noncoding RNA LINC00460 promotes the progression of cervical cancer via regulation of the miR-361-3p/Gli1 axis.
Li F, Zhu W, Wang Z
Human cell 2022 Jul;35(4):1306
Human cell 2022 Jul;35(4):1306
Integrated multicomponent analysis based on UHPLC-Q-Exactive Orbitrap-MS and network pharmacology to elucidate the potential mechanism of Baoyuan decoction against idiopathic pulmonary fibrosis.
Zhang B, Gao D, Xu G, Zhu W, Liu J, Sun R, Wang L, Zhang C, Ding Q, Shi Y
Phytochemical analysis : PCA 2022 Jul;33(5):678-695
Phytochemical analysis : PCA 2022 Jul;33(5):678-695
Iron-regulated assembly of the cytosolic iron-sulfur cluster biogenesis machinery.
Fan X, Barshop WD, Vashisht AA, Pandey V, Leal S, Rayatpisheh S, Jami-Alahmadi Y, Sha J, Wohlschlegel JA
The Journal of biological chemistry 2022 Jul;298(7):102094
The Journal of biological chemistry 2022 Jul;298(7):102094
NUMB facilitates autophagy initiation through targeting SCF(β-TrCP2) complex.
Li H, Shu S, Zhou M, Chen Y, Xiao A, Ma Y, Zhu F, Hu Z, Nie J
Cell death and differentiation 2022 Jul;29(7):1409-1422
Cell death and differentiation 2022 Jul;29(7):1409-1422
Clusterin protects against Cr(VI)-induced oxidative stress-associated hepatotoxicity by mediating the Akt-Keap1-Nrf2 signaling pathway.
Ma Y, Li S, Tang S, Ye S, Liang N, Liang Y, Xiao F
Environmental science and pollution research international 2022 Jul;29(34):52289-52301
Environmental science and pollution research international 2022 Jul;29(34):52289-52301
Hypothermia preconditioning improves cardiac contractility after cardiopulmonary resuscitation through AMPK-activated mitophagy.
Lu Y, Zhang C, Chen J, Zou Q, Li B, Wei H, Chang MP, Liao X, Hu C
Experimental biology and medicine (Maywood, N.J.) 2022 Jul;247(14):1277-1286
Experimental biology and medicine (Maywood, N.J.) 2022 Jul;247(14):1277-1286
Cancer germline antigen gene MAGEB2 promotes cell invasion and correlates with immune microenvironment and immunotherapeutic efficiency in laryngeal cancer.
Cui J, Chen Y, Ou Y, Liu G, Wen Q, Zhu W, Liang L, Chen Z, Yang H, Wang L, Wei M
Clinical immunology (Orlando, Fla.) 2022 Jul;240:109045
Clinical immunology (Orlando, Fla.) 2022 Jul;240:109045
Germacrone induces caspase-3/GSDME activation and enhances ROS production, causing HepG2 pyroptosis.
Sun X, Zhong X, Ma W, Feng W, Huang Q, Ma M, Lv M, Hu R, Han Z, Li J, Zhou X
Experimental and therapeutic medicine 2022 Jul;24(1):456
Experimental and therapeutic medicine 2022 Jul;24(1):456
High expression of 14-3-3ơ indicates poor prognosis and progression of lung adenocarcinoma.
Feng J, Leng J, Zhao C, Guo J, Chen Y, Li H
Oncology letters 2022 Jul;24(1):203
Oncology letters 2022 Jul;24(1):203
Selenium alleviates cadmium-induced aging via mitochondrial quality control in the livers of sheep.
Xiong Z, Yang F, Xu T, Yang Y, Wang F, Zhou G, Wang Q, Guo X, Xing C, Bai H, Chen J, Wu Y, Yang S, Cao H
Journal of inorganic biochemistry 2022 Jul;232:111818
Journal of inorganic biochemistry 2022 Jul;232:111818
Lysyl oxidase-like 2 inhibitor rescues D-galactose-induced skeletal muscle fibrosis.
Wu Y, Wu Y, Yang Y, Yu J, Wu J, Liao Z, Guo A, Sun Y, Zhao Y, Chen J, Xiao Q
Aging cell 2022 Jul;21(7):e13659
Aging cell 2022 Jul;21(7):e13659
Inhibition of Cpt1a alleviates oxidative stress-induced chondrocyte senescence via regulating mitochondrial dysfunction and activating mitophagy.
Jiang N, Xing B, Peng R, Shang J, Wu B, Xiao P, Lin S, Xu X, Lu H
Mechanisms of ageing and development 2022 Jul;205:111688
Mechanisms of ageing and development 2022 Jul;205:111688
S1PR2/RhoA/ROCK1 pathway promotes inflammatory bowel disease by inducing intestinal vascular endothelial barrier damage and M1 macrophage polarization.
Wang X, Chen S, Xiang H, Wang X, Xiao J, Zhao S, Shu Z, Ouyang J, Liang Z, Deng M, Chen X, Zhang J, Liu H, Quan Q, Gao P, Fan J, Chen AF, Lu H
Biochemical pharmacology 2022 Jul;201:115077
Biochemical pharmacology 2022 Jul;201:115077
Mitochondrial and glucose metabolic dysfunctions in granulosa cells induce impaired oocytes of polycystic ovary syndrome through Sirtuin 3.
Zhang Q, Ren J, Wang F, Pan M, Cui L, Li M, Qu F
Free radical biology & medicine 2022 Jul;187:1-16
Free radical biology & medicine 2022 Jul;187:1-16
Newcastle disease virus degrades SIRT3 via PINK1-PRKN-dependent mitophagy to reprogram energy metabolism in infected cells.
Gong Y, Tang N, Liu P, Sun Y, Lu S, Liu W, Tan L, Song C, Qiu X, Liao Y, Yu S, Liu X, Lin SH, Ding C
Autophagy 2022 Jul;18(7):1503-1521
Autophagy 2022 Jul;18(7):1503-1521
DEPTOR exacerbates bone-fat imbalance in osteoporosis by transcriptionally modulating BMSC differentiation.
Ouyang Z, Kang D, Li K, Liang G, Liu Z, Mai Q, Chen Q, Yao C, Wei R, Tan X, Bai X, Huang B, Li Q
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Jul;151:113164
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Jul;151:113164
Endogenous and exogenous hydrogen sulfide modulates urothelial bladder carcinoma development in human cell lines.
Panza E, Bello I, Smimmo M, Brancaleone V, Mitidieri E, Bucci M, Cirino G, Sorrentino R, D Emmanuele di Villa Bianca R
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Jul;151:113137
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Jul;151:113137
Berberine exerts protective effects on cardiac senescence by regulating the Klotho/SIRT1 signaling pathway.
Li C, Jiang S, Wang H, Wang Y, Han Y, Jiang J
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Jul;151:113097
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Jul;151:113097
Curcumin exerts chondroprotective effects against osteoarthritis by promoting AMPK/PINK1/Parkin-mediated mitophagy.
Jin Z, Chang B, Wei Y, Yang Y, Zhang H, Liu J, Piao L, Bai L
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Jul;151:113092
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Jul;151:113092
KGF-2 Regulates STAP-2-Mediated Signal Transducer and Activator of Transcription 3 Signaling and Reduces Skin Scar Formation.
Zhou Q, Gong J, Bi J, Yang X, Zhang L, Lu C, Li L, Chen M, Cai J, Yang R, Li X, Li Z, Wang X
The Journal of investigative dermatology 2022 Jul;142(7):2003-2013.e5
The Journal of investigative dermatology 2022 Jul;142(7):2003-2013.e5
BUB1 predicts poor prognosis and immune status in liver hepatocellular carcinoma.
Qi W, Bai Y, Wang Y, Liu L, Zhang Y, Yu Y, Chen H
APMIS : acta pathologica, microbiologica, et immunologica Scandinavica 2022 Jul;130(7):371-382
APMIS : acta pathologica, microbiologica, et immunologica Scandinavica 2022 Jul;130(7):371-382
Design, synthesis and biological evaluation of (R)-5-methylpyrrolidin-2-ones as p300 bromodomain inhibitors with Anti-Tumor activities in multiple tumor lines.
Liu R, Yang H, Chen Z, Zhou K, Shi Q, Li J, Huang Y, Huang X, Li Y
Bioorganic chemistry 2022 Jul;124:105803
Bioorganic chemistry 2022 Jul;124:105803
SHMT2 promotes the tumorigenesis of renal cell carcinoma by regulating the m6A modification of PPAT.
Huo FC, Xie M, Zhu ZM, Zheng JN, Pei DS
Genomics 2022 Jul;114(4):110424
Genomics 2022 Jul;114(4):110424
GNAQ T96S mutation abrogates the ability of wild-type GNAQ to induce apoptosis by phosphorylating annexin A2 in natural killer/T cell lymphoma.
Zhao W, Zhang M, Wang G, Liu E, Jiang G, Zhang Y, Zhang D, Jian X, Zhao H, Zhang C, Li W
Cancer science 2022 Jul;113(7):2288-2296
Cancer science 2022 Jul;113(7):2288-2296
Homosalate boosts the release of tumour-derived extracellular vesicles with protection against anchorage-loss property.
Grisard E, Nevo N, Lescure A, Doll S, Corbé M, Jouve M, Lavieu G, Joliot A, Nery ED, Martin-Jaular L, Théry C
Journal of extracellular vesicles 2022 Jul;11(7):e12242
Journal of extracellular vesicles 2022 Jul;11(7):e12242
IQGAP1 is positively correlated with PD-L1 and regulates its expression via mediating STAT proteins phosphorylation.
Chen Y, Mei J, Zhang P, Liu J, Chen L, Wu L, Zhang Y
International immunopharmacology 2022 Jul;108:108897
International immunopharmacology 2022 Jul;108:108897
Trans-anethole ameliorates LPS-induced inflammation via suppression of TLR4/NF-κB pathway in IEC-6 cells.
Yu C, Wang D, Li Q, Tong Y, Yang Z, Wang T
International immunopharmacology 2022 Jul;108:108872
International immunopharmacology 2022 Jul;108:108872
Asiaticoside ameliorates osteoarthritis progression through activation of Nrf2/HO-1 and inhibition of the NF-κB pathway.
Luo P, Huang Q, Chen S, Wang Y, Dou H
International immunopharmacology 2022 Jul;108:108864
International immunopharmacology 2022 Jul;108:108864
Recombinant humanized IgG1 maintain liver triglyceride homeostasis through Arylacetamide deacetylase in ApoE(-/-) mice.
Xiao S, Lin R, Duan R, Li Z, Tang D, Liu X, Liu Y, Zhao M
International immunopharmacology 2022 Jul;108:108741
International immunopharmacology 2022 Jul;108:108741
Asperuloside inhibited epithelial-mesenchymal transition in colitis associated cancer via activation of vitamin D receptor.
Lu Y, Guan T, Xu S, Chen YE, Shen Q, Zhu S, Liu Y, Liang J, Hou S
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Jul;101:154070
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Jul;101:154070
Palbociclib regulates the expression of dihydrofolate reductase and the cell cycle to inhibit t (11;14) multiple myeloma.
Wang Y, Wang H, Wang X
Annals of translational medicine 2022 Jul;10(13):746
Annals of translational medicine 2022 Jul;10(13):746
Secretion of the disulfide bond generating catalyst QSOX1 from pancreatic tumor cells into the extracellular matrix: association with extracellular vesicles and matrix proteins.
Millar-Haskell CS, Sperduto JL, Slater JH, Thorpe C, Gleghorn JP
Journal of extracellular biology 2022 Jul;1(7)
Journal of extracellular biology 2022 Jul;1(7)
Combination of midostaurin and ATRA exerts dose-dependent dual effects on acute myeloid leukemia cells with wild type FLT3.
Lu H, Weng XQ, Sheng Y, Wu J, Xi HM, Cai X
BMC cancer 2022 Jul 9;22(1):749
BMC cancer 2022 Jul 9;22(1):749
H3K36me2 methyltransferase NSD2 orchestrates epigenetic reprogramming during spermatogenesis.
Li Z, Zhang X, Xie S, Liu X, Fei C, Huang X, Tang Y, Zhou LQ
Nucleic acids research 2022 Jul 8;50(12):6786-6800
Nucleic acids research 2022 Jul 8;50(12):6786-6800
Eleutheroside E supplementation prevents radiation-induced cognitive impairment and activates PKA signaling via gut microbiota.
Song C, Duan F, Ju T, Qin Y, Zeng D, Shan S, Shi Y, Zhang Y, Lu W
Communications biology 2022 Jul 8;5(1):680
Communications biology 2022 Jul 8;5(1):680
Human Platelet Lysate Induces Antiviral Responses against Parechovirus A3.
Jan MW, Chiu CY, Chen JJ, Chang TH, Tsai KJ
Viruses 2022 Jul 8;14(7)
Viruses 2022 Jul 8;14(7)
Low expression of PRDM5 predicts poor prognosis of esophageal squamous cell carcinoma.
Guo J, Yang Q, Wei S, Shao J, Zhao T, Guo L, Liu J, Chen J, Wang G
BMC cancer 2022 Jul 7;22(1):745
BMC cancer 2022 Jul 7;22(1):745
Protein nanoparticle-induced osmotic pressure gradients modify pulmonary edema through hyperpermeability in acute respiratory distress syndrome.
Qian Z, Wang Q, Qiu Z, Li D, Zhang C, Xiong X, Zheng Z, Ruan Q, Guo Y, Guo J
Journal of nanobiotechnology 2022 Jul 6;20(1):314
Journal of nanobiotechnology 2022 Jul 6;20(1):314
Mitochondrial fission induces immunoescape in solid tumors through decreasing MHC-I surface expression.
Lei X, Lin H, Wang J, Ou Z, Ruan Y, Sadagopan A, Chen W, Xie S, Chen B, Li Q, Wang J, Lin H, Zhu X, Yuan X, Tian T, Lv X, Fu S, Zhu X, Zhou J, Pan G, Xia X, Tannous BA, Ferrone S, Fan S, Li J
Nature communications 2022 Jul 6;13(1):3882
Nature communications 2022 Jul 6;13(1):3882
Cholecystokinin and glucagon-like peptide-1 analogues regulate intestinal tight junction, inflammation, dopaminergic neurons and α-synuclein accumulation in the colon of two Parkinson's disease mouse models.
Su Y, Liu N, Zhang Z, Li H, Ma J, Yuan Y, Shi M, Liu J, Zhao Z, Zhang Z, Holscher C
European journal of pharmacology 2022 Jul 5;926:175029
European journal of pharmacology 2022 Jul 5;926:175029
Spatiotemporal regulation of insulin signaling by liquid-liquid phase separation.
Zhou K, Chen Q, Chen J, Liang D, Feng W, Liu M, Wang Q, Wang R, Ouyang Q, Quan C, Chen S
Cell discovery 2022 Jul 5;8(1):64
Cell discovery 2022 Jul 5;8(1):64
Photoaffinity Labeling-Based Chemoproteomic Strategy Reveals RBBP4 as a Cellular Target of Protopanaxadiol against Colorectal Cancer Cells.
Zhuo FF, Guo Q, Zheng YZ, Liu TT, Yang Z, Xu QH, Jiang Y, Liu D, Zeng KW, Tu PF
Chembiochem : a European journal of chemical biology 2022 Jul 5;23(13):e202200038
Chembiochem : a European journal of chemical biology 2022 Jul 5;23(13):e202200038
Peptide PDHPS1 Inhibits Ovarian Cancer Growth through Disrupting YAP Signaling.
Pan X, Geng Z, Li J, Li X, Zhang M, Wang X, Cong Y, Huang K, Xu J, Jia X
Molecular cancer therapeutics 2022 Jul 5;21(7):1160-1170
Molecular cancer therapeutics 2022 Jul 5;21(7):1160-1170
Expression of lncRNA APF in Peripheral Blood of Patients with Acute Myocardial Infarction Caused by Coronary Heart Disease and its Clinical Significance.
Zeng H, Hu F, Duan Y, Li H, Wang Y
International heart journal 2022 Jul 30;63(4):742-748
International heart journal 2022 Jul 30;63(4):742-748
Identification of mutant p53-specific proteins interaction network using TurboID-based proximity labeling.
Hu S, Ouyang J, Zheng G, Lu Y, Zhu Q, Wang B, Ye L, Zhu C
Biochemical and biophysical research communications 2022 Jul 30;615:163-171
Biochemical and biophysical research communications 2022 Jul 30;615:163-171
CDC-like kinase 4 deficiency contributes to pathological cardiac hypertrophy by modulating NEXN phosphorylation.
Huang J, Wang L, Shen Y, Zhang S, Zhou Y, Du J, Ma X, Liu Y, Liang D, Shi D, Ma H, Li L, Zhang Q, Chen YH
Nature communications 2022 Jul 30;13(1):4433
Nature communications 2022 Jul 30;13(1):4433
Mitochondrial proteostasis stress in muscle drives a long-range protective response to alleviate dietary obesity independently of ATF4.
Guo Q, Xu Z, Zhou D, Fu T, Wang W, Sun W, Xiao L, Liu L, Ding C, Yin Y, Zhou Z, Sun Z, Zhu Y, Zhou W, Jia Y, Xue J, Chen Y, Chen XW, Piao HL, Lu B, Gan Z
Science advances 2022 Jul 29;8(30):eabo0340
Science advances 2022 Jul 29;8(30):eabo0340
PTPRO knockdown protects against inflammation in hemorrhage shock-induced lung injury involving the NF-κB signaling pathway.
Huan Z, Tang Y, Xu C, Cai J, Yao H, Wang Y, Bu F, Ge X
Respiratory research 2022 Jul 29;23(1):195
Respiratory research 2022 Jul 29;23(1):195
Discovery of Novel Phosphoinositide-3-Kinase α Inhibitors with High Selectivity, Excellent Bioavailability, and Long-Acting Efficacy for Gastric Cancer.
Hou Y, Zhang F, Min W, Yuan K, Kuang W, Wang X, Zhu Y, Sun C, Xia F, Wang Y, Zhang H, Wang L, Yang P
Journal of medicinal chemistry 2022 Jul 28;65(14):9873-9892
Journal of medicinal chemistry 2022 Jul 28;65(14):9873-9892
ISX-9 potentiates CaMKIIδ-mediated BMAL1 activation to enhance circadian amplitude.
Li H, Ou J, Li Y, Xu N, Li Q, Wu P, Peng C, Tang YC, Chang HC
Communications biology 2022 Jul 28;5(1):750
Communications biology 2022 Jul 28;5(1):750
Peptidome analysis of human intrauterine adhesion tissues and the identification of antifibrotic peptide.
Hua X, Zhang Y, Xu J, Xu L, Shi Y, Yang D, Gu X, Wang S, Jia X, Xu F, Chen J, Ying X
Journal of biomedical research 2022 Jul 28;36(4):280-296
Journal of biomedical research 2022 Jul 28;36(4):280-296
Microtubule associated protein 4 phosphorylation-induced epithelial-to-mesenchymal transition of podocyte leads to proteinuria in diabetic nephropathy.
Li L, Feng Y, Zhang J, Zhang Q, Ren J, Sun C, Li S, Lei X, Luo G, Hu J, Huang Y
Cell communication and signaling : CCS 2022 Jul 28;20(1):115
Cell communication and signaling : CCS 2022 Jul 28;20(1):115
Bone marrow mesenchymal stem cells inhibit hepatic fibrosis via the AABR07028795.2/rno-miR-667-5p axis.
Feng Y, Li Y, Xu M, Meng H, Dai C, Yao Z, Lin N
Stem cell research & therapy 2022 Jul 28;13(1):375
Stem cell research & therapy 2022 Jul 28;13(1):375
GCN5/KAT2A contributes to axon growth and neurogenesis.
Lin G, Lin H, Zhuo R, He W, Ma C, Liu Y, Liu M
Neuroscience letters 2022 Jul 27;784:136742
Neuroscience letters 2022 Jul 27;784:136742
Effects of Artemisinin on Escherichia coli-Induced Mastitis in Bovine Mammary Epithelial Cells and Mice.
Li Z, Hu J, Wang X, Du Y, Yin J, Gao J, Han B, Cui S, Liu Y, Liu J
Veterinary sciences 2022 Jul 26;9(8)
Veterinary sciences 2022 Jul 26;9(8)
Inhibition of CSPG receptor PTPσ promotes migration of newly born neuroblasts, axonal sprouting, and recovery from stroke.
Luo F, Wang J, Zhang Z, You Z, Bedolla A, Okwubido-Williams F, Huang LF, Silver J, Luo Y
Cell reports 2022 Jul 26;40(4):111137
Cell reports 2022 Jul 26;40(4):111137
Curcumin Induces Apoptosis of Chemoresistant Lung Cancer Cells via ROS-Regulated p38 MAPK Phosphorylation.
Wu MF, Huang YH, Chiu LY, Cherng SH, Sheu GT, Yang TY
International journal of molecular sciences 2022 Jul 26;23(15)
International journal of molecular sciences 2022 Jul 26;23(15)
Genomic signature of MTOR could be an immunogenicity marker in human colorectal cancer.
Wang C, Aikemu B, Shao Y, Zhang S, Yang G, Hong H, Huang L, Jia H, Yang X, Zheng M, Sun J, Li J
BMC cancer 2022 Jul 26;22(1):818
BMC cancer 2022 Jul 26;22(1):818
Wharton's jelly mesenchymal stem cell-derived small extracellular vesicles as natural nanoparticles to attenuate cartilage injury via microRNA regulation.
Chen P, Tang S, Gao H, Zhang H, Chen C, Fang Z, Peng G, Weng H, Chen A, Zhang C, Qiu Z, Li S, Chen J, Chen L, Chen X
International journal of pharmaceutics 2022 Jul 25;623:121952
International journal of pharmaceutics 2022 Jul 25;623:121952
Albumin-induced premature senescence in human renal proximal tubular cells and its relationship with intercellular fibrosis.
Lu W, Ren S, Dong W, Li X, Zheng Z, Jia Y, Xue Y
Acta biochimica et biophysica Sinica 2022 Jul 25;54(7):893-903
Acta biochimica et biophysica Sinica 2022 Jul 25;54(7):893-903
Increased cytochrome C threonine 50 phosphorylation in aging heart as a novel defensive signaling against hypoxia/reoxygenation induced apoptosis.
Li F, Sun H, Lin X, Li Q, Zhao D, Cheng Z, Liu J, Fan Q
Aging 2022 Jul 25;14(14):5699-5709
Aging 2022 Jul 25;14(14):5699-5709
CysLT(2)R Antagonist HAMI 3379 Ameliorates Post-Stroke Depression through NLRP3 Inflammasome/Pyroptosis Pathway in Gerbils.
Zhou L, Zhang J, Han X, Fang J, Zhou S, Lu L, Shi Q, Ying H
Brain sciences 2022 Jul 24;12(8)
Brain sciences 2022 Jul 24;12(8)
CTNND1 variants cause familial exudative vitreoretinopathy through the Wnt/cadherin axis.
Yang M, Li S, Huang L, Zhao R, Dai E, Jiang X, He Y, Lu J, Peng L, Liu W, Zhang Z, Jiang D, Zhang Y, Jiang Z, Yang Y, Zhao P, Zhu X, Ding X, Yang Z
JCI insight 2022 Jul 22;7(14)
JCI insight 2022 Jul 22;7(14)
ARHGEF37 overexpression promotes extravasation and metastasis of hepatocellular carcinoma via directly activating Cdc42.
Zhang X, Ren L, Wu J, Feng R, Chen Y, Li R, Wu M, Zheng M, Wu XG, Luo W, He H, Huang Y, Tang M, Li J
Journal of experimental & clinical cancer research : CR 2022 Jul 22;41(1):230
Journal of experimental & clinical cancer research : CR 2022 Jul 22;41(1):230
NCAPG promotes the proliferation of hepatocellular carcinoma through the CKII-dependent regulation of PTEN.
Zhang R, Ai J, Wang J, Sun C, Lu H, He A, Li M, Liao Y, Lei J, Zhou F, Wu L, Liao W
Journal of translational medicine 2022 Jul 21;20(1):325
Journal of translational medicine 2022 Jul 21;20(1):325
TGFβ1-transfected tendon stem cells promote tendon fibrosis.
Yu HB, Xiong J, Zhang HZ, Chen Q, Xie XY
Journal of orthopaedic surgery and research 2022 Jul 21;17(1):358
Journal of orthopaedic surgery and research 2022 Jul 21;17(1):358
Overexpression of NNMT in Glioma Aggravates Tumor Cell Progression: An Emerging Therapeutic Target.
Sun W, Zou Y, Cai Z, Huang J, Hong X, Liang Q, Jin W
Cancers 2022 Jul 21;14(14)
Cancers 2022 Jul 21;14(14)
Self-Assembly of a Multifunction DNA Tetrahedron for Effective Delivery of Aptamer PL1 and Pcsk9 siRNA Potentiate Immune Checkpoint Therapy for Colorectal Cancer.
Guo W, Gao H, Li H, Ge S, Zhang F, Wang L, Shi H, Han A
ACS applied materials & interfaces 2022 Jul 20;14(28):31634-31644
ACS applied materials & interfaces 2022 Jul 20;14(28):31634-31644
Transcriptomic profiling revealed the role of apigenin-4'-O-α-L-rhamnoside in inhibiting the activation of rheumatoid arthritis fibroblast-like synoviocytes via MAPK signaling pathway.
Cao D, Fan Q, Li Z, Chen M, Jiang Y, Lin R, Li J, Zhao C
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Jul 20;102:154201
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Jul 20;102:154201
An integrated network pharmacology and cell metabolomics approach to reveal the role of rhein, a novel PPARα agonist, against renal fibrosis by activating the PPARα-CPT1A axis.
Xiao Q, Yu X, Yu X, Liu S, Jiang J, Cheng Y, Lin H, Wang Y, Zhang X, Ye X, Xiang Z
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Jul 20;102:154147
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Jul 20;102:154147
Magnetic hyperthermia induces effective and genuine immunogenic tumor cell death with respect to exogenous heating.
Yan B, Liu C, Wang S, Li H, Jiao J, Lee WSV, Zhang S, Hou Y, Hou Y, Ma X, Fan H, Lv Y, Liu X
Journal of materials chemistry. B 2022 Jul 20;10(28):5364-5374
Journal of materials chemistry. B 2022 Jul 20;10(28):5364-5374
Single-cell multiomics analysis reveals regulatory programs in clear cell renal cell carcinoma.
Long Z, Sun C, Tang M, Wang Y, Ma J, Yu J, Wei J, Ma J, Wang B, Xie Q, Wen J
Cell discovery 2022 Jul 19;8(1):68
Cell discovery 2022 Jul 19;8(1):68
N-glycosylation of GDF15 abolishes its inhibitory effect on EGFR in AR inhibitor-resistant prostate cancer cells.
Wang R, Wen P, Yang G, Feng Y, Mi Y, Wang X, Zhu S, Chen YQ
Cell death & disease 2022 Jul 19;13(7):626
Cell death & disease 2022 Jul 19;13(7):626
Viral evasion of PKR restriction by reprogramming cellular stress granules.
Gao P, Liu Y, Wang H, Chai Y, Weng W, Zhang Y, Zhou L, Ge X, Guo X, Han J, Yang H
Proceedings of the National Academy of Sciences of the United States of America 2022 Jul 19;119(29):e2201169119
Proceedings of the National Academy of Sciences of the United States of America 2022 Jul 19;119(29):e2201169119
FL-DTD: an integrated pipeline to predict the drug interacting targets by feedback loop-based network analysis.
Lu D, Pan R, Wu W, Zhang Y, Li S, Xu H, Huang J, Xia J, Wang Q, Luan X, Lv C, Zhang W, Meng G
Briefings in bioinformatics 2022 Jul 18;23(4)
Briefings in bioinformatics 2022 Jul 18;23(4)
Glycyrrhizic Acid Attenuates Pulmonary Fibrosis of Silicosis by Inhibiting the Interaction between HMGB1 and BRG1 through PI3K/Akt/mTOR Pathway.
Niu Z, Lin J, Hao C, Xu X, Wang C, Dai K, Deng X, Deng M, Guo Y, Yao W
International journal of environmental research and public health 2022 Jul 18;19(14)
International journal of environmental research and public health 2022 Jul 18;19(14)
ZIP14 is involved in iron deposition and triggers ferroptosis in diabetic nephropathy.
Wu K, Fei L, Wang X, Lei Y, Yu L, Xu W, Chen J, Zhu E, Zhong M, Huang M, Xi J, Yin F, Yan Z, Zhao X, Tang C, Patzak A, Liu X, Zheng Z
Metallomics : integrated biometal science 2022 Jul 18;14(7)
Metallomics : integrated biometal science 2022 Jul 18;14(7)
Hepatocyte growth factor derived from senescent cells attenuates cell competition-induced apical elimination of oncogenic cells.
Igarashi N, Miyata K, Loo TM, Chiba M, Hanyu A, Nishio M, Kawasaki H, Zheng H, Toyokuni S, Kon S, Moriyama K, Fujita Y, Takahashi A
Nature communications 2022 Jul 18;13(1):4157
Nature communications 2022 Jul 18;13(1):4157
A pan-cancer analysis of thioredoxin-interacting protein as an immunological and prognostic biomarker.
Guo X, Huang M, Zhang H, Chen Q, Hu Y, Meng Y, Wu C, Tu C, Liu Y, Li A, Li Q, Zhou P, Liu S
Cancer cell international 2022 Jul 17;22(1):230
Cancer cell international 2022 Jul 17;22(1):230
Identification of benzamides derivatives of norfloxacin as promising microRNA-21 inhibitors via repressing its transcription.
Xi XX, Hei YY, Guo Y, Zhao HY, Xin M, Lu S, Jiang C, Zhang SQ
Bioorganic & medicinal chemistry 2022 Jul 15;66:116803
Bioorganic & medicinal chemistry 2022 Jul 15;66:116803
Deficiency of NARFL increases transcription of NADPH oxidases and ROS production impairing the function of endothelial cells.
Liu HZ, Peng J, Zhao MZ, Xu Y
Life sciences 2022 Jul 15;301:120567
Life sciences 2022 Jul 15;301:120567
The Chinese medicine Fufang Zhenzhu Tiaozhi capsule protects against atherosclerosis by suppressing EndMT via modulating Akt1/β-catenin signaling pathway.
Diao H, Cheng J, Huang X, Huang B, Shao X, Zhao J, Lan D, Zhu Q, Yan M, Zhang Y, Rong X, Guo J
Journal of ethnopharmacology 2022 Jul 15;293:115261
Journal of ethnopharmacology 2022 Jul 15;293:115261
The SARS-CoV-2 protein NSP2 impairs the silencing capacity of the human 4EHP-GIGYF2 complex.
Zou L, Moch C, Graille M, Chapat C
iScience 2022 Jul 15;25(7):104646
iScience 2022 Jul 15;25(7):104646
The role of ciliopathy-associated type 3 adenylyl cyclase in infanticidal behavior in virgin adult male mice.
Wu X, Yang D, Zhou Y, Li S, Wang Z
iScience 2022 Jul 15;25(7):104534
iScience 2022 Jul 15;25(7):104534
GCN5 participates in KLF4-VEGFA feedback to promote endometrial angiogenesis.
Cao C, Zhou Y, Zhang Y, Ma Y, Du S, Fan L, Niu R, Zhang Y, He M
iScience 2022 Jul 15;25(7):104509
iScience 2022 Jul 15;25(7):104509
Sex-Based Differences in Human Neutrophil Chemorepulsion.
Consalvo KM, Kirolos SA, Sestak CE, Gomer RH
Journal of immunology (Baltimore, Md. : 1950) 2022 Jul 15;209(2):354-367
Journal of immunology (Baltimore, Md. : 1950) 2022 Jul 15;209(2):354-367
YTHDF3 Facilitates eIF2AK2 and eIF3A Recruitment on mRNAs to Regulate Translational Processes in Oxaliplatin-Resistant Colorectal Cancer.
Zhao Y, Zhao H, Zhang D, Quan Q, Ge Y, Li L, Guo L
ACS chemical biology 2022 Jul 15;17(7):1778-1788
ACS chemical biology 2022 Jul 15;17(7):1778-1788
CCL20/CCR6 axis mediates macrophages to promote proliferation and migration of ESCs by blocking autophagic flux in endometriosis.
Tan J, Xu T, Gou Y, Wang H, Liang Z, Cao Y, Wang H, Yu Y, Jiao N, Zhang Z
Stem cell research & therapy 2022 Jul 15;13(1):294
Stem cell research & therapy 2022 Jul 15;13(1):294
RBM47 inhibits hepatocellular carcinoma progression by targeting UPF1 as a DNA/RNA regulator.
Guo T, You K, Chen X, Sun Y, Wu Y, Wu P, Jiang Y
Cell death discovery 2022 Jul 14;8(1):320
Cell death discovery 2022 Jul 14;8(1):320
Chronic stress-induced depression requires the recruitment of peripheral Th17 cells into the brain.
Peng Z, Peng S, Lin K, Zhao B, Wei L, Tuo Q, Liao D, Yuan T, Shi Z
Journal of neuroinflammation 2022 Jul 14;19(1):186
Journal of neuroinflammation 2022 Jul 14;19(1):186
ZEB2/TWIST1/PRMT5/NuRD Multicomplex Contributes to the Epigenetic Regulation of EMT and Metastasis in Colorectal Carcinoma.
Zheng Y, Dai M, Dong Y, Yu H, Liu T, Feng X, Yu B, Zhang H, Wu J, Kong W, Yu X, Wu H
Cancers 2022 Jul 14;14(14)
Cancers 2022 Jul 14;14(14)
Histone demethylase JMJD3 downregulation protects against aberrant force-induced osteoarthritis through epigenetic control of NR4A1.
Jin Y, Liu Z, Li Z, Li H, Zhu C, Li R, Zhou T, Fang B
International journal of oral science 2022 Jul 14;14(1):34
International journal of oral science 2022 Jul 14;14(1):34
Circ_0000181 regulates miR-667-5p/NLRC4 axis to promote pyroptosis progression in diabetic nephropathy.
Li Y, Yu W, Xiong H, Yuan F
Scientific reports 2022 Jul 14;12(1):11994
Scientific reports 2022 Jul 14;12(1):11994
FUBP3 Degrades the Porcine Epidemic Diarrhea Virus Nucleocapsid Protein and Induces the Production of Type I Interferon.
Dong S, Kong N, Wang C, Li Y, Sun D, Qin W, Zhai H, Zhai X, Yang X, Ye C, Ye M, Liu C, Yu L, Zheng H, Tong W, Yu H, Zhang W, Tong G, Shan T
Journal of virology 2022 Jul 13;96(13):e0061822
Journal of virology 2022 Jul 13;96(13):e0061822
Transient neuroinflammation following surgery contributes to long-lasting cognitive decline in elderly rats via dysfunction of synaptic NMDA receptor.
Chen B, Qin G, Xiao J, Deng X, Lin A, Liu H
Journal of neuroinflammation 2022 Jul 13;19(1):181
Journal of neuroinflammation 2022 Jul 13;19(1):181
Overexpressed COL3A1 has prognostic value in human esophageal squamous cell carcinoma and promotes the aggressiveness of esophageal squamous cell carcinoma by activating the NF-κB pathway.
Zhou J, Yang Y, Zhang H, Luan S, Xiao X, Li X, Fang P, Shang Q, Chen L, Zeng X, Yuan Y
Biochemical and biophysical research communications 2022 Jul 12;613:193-200
Biochemical and biophysical research communications 2022 Jul 12;613:193-200
Inhibition of SIRT2 promotes APP acetylation and ameliorates cognitive impairment in APP/PS1 transgenic mice.
Bai N, Li N, Cheng R, Guan Y, Zhao X, Song Z, Xu H, Yi F, Jiang B, Li X, Wu X, Jiang C, Zhou T, Guo Q, Guo W, Feng Y, Wang Z, Ma M, Yu Y, Wang Z, Zhang S, Wang C, Zhao W, Liu S, Song X, Liu H, Cao L
Cell reports 2022 Jul 12;40(2):111062
Cell reports 2022 Jul 12;40(2):111062
BMSC-derived exosomes protect against kidney injury through regulating klotho in 5/6 nephrectomy rats.
Wan F, Yang RC, Tang YW, Tang XL, Ye T, Zheng J, Zhang HQ, Lin Y
European journal of medical research 2022 Jul 11;27(1):118
European journal of medical research 2022 Jul 11;27(1):118
Caffeine Decreases Hepcidin Expression to Alleviate Aberrant Iron Metabolism under Inflammation by Regulating the IL-6/STAT3 Pathway.
Li ZD, Geng MY, Dou SR, Wang X, Zhang ZH, Chang YZ
Life (Basel, Switzerland) 2022 Jul 10;12(7)
Life (Basel, Switzerland) 2022 Jul 10;12(7)
TFCP2, a binding protein of ATF3, promotes the progression of glioma by activating the synthesis of serine.
Luo X, Ge J, Liu J, Liu Z, Bi C, Lan S
Experimental cell research 2022 Jul 1;416(1):113136
Experimental cell research 2022 Jul 1;416(1):113136
Fenbendazole and its synthetic analog interfere with HeLa cells' proliferation and energy metabolism via inducing oxidative stress and modulating MEK3/6-p38-MAPK pathway.
Peng Y, Pan J, Ou F, Wang W, Hu H, Chen L, Zeng S, Zeng K, Yu L
Chemico-biological interactions 2022 Jul 1;361:109983
Chemico-biological interactions 2022 Jul 1;361:109983
Belumosudil, ROCK2-specific inhibitor, alleviates cardiac fibrosis by inhibiting cardiac fibroblasts activation.
Liu Q, Li HY, Wang SJ, Huang SQ, Yue Y, Maihemuti A, Zhang Y, Huang L, Luo L, Feng KN, Wu ZK
American journal of physiology. Heart and circulatory physiology 2022 Jul 1;323(1):H235-H247
American journal of physiology. Heart and circulatory physiology 2022 Jul 1;323(1):H235-H247
DOCK2 contributes to pulmonary fibrosis by promoting lung fibroblast to myofibroblast transition.
Guo X, Adeyanju O, Sunil C, Mandlem V, Olajuyin A, Huang S, Chen SY, Idell S, Tucker TA, Qian G
American journal of physiology. Cell physiology 2022 Jul 1;323(1):C133-C144
American journal of physiology. Cell physiology 2022 Jul 1;323(1):C133-C144
Combined exposure of lead and high-fat diet enhanced cognitive decline via interacting with CREB-BDNF signaling in male rats.
Liu R, Bai L, Liu M, Wang R, Wu Y, Li Q, Ba Y, Zhang H, Zhou G, Yu F, Huang H
Environmental pollution (Barking, Essex : 1987) 2022 Jul 1;304:119200
Environmental pollution (Barking, Essex : 1987) 2022 Jul 1;304:119200
Ambient fine particulate matter exposure disrupts placental autophagy and fetal development in gestational mice.
Li R, Peng J, Zhang W, Wu Y, Hu R, Chen R, Gu W, Zhang L, Qin L, Zhong M, Chen LC, Sun Q, Liu C
Ecotoxicology and environmental safety 2022 Jul 1;239:113680
Ecotoxicology and environmental safety 2022 Jul 1;239:113680
HMGB1-NLRP3-P2X7R pathway participates in PM(2.5)-induced hippocampal neuron impairment by regulating microglia activation.
Liu C, She Y, Huang J, Liu Y, Li W, Zhang C, Zhang T, Yu L
Ecotoxicology and environmental safety 2022 Jul 1;239:113664
Ecotoxicology and environmental safety 2022 Jul 1;239:113664
Kir2.1 channel regulates macrophage polarization via the Ca2+/CaMK II/ERK/NF-κB signaling pathway.
Chen K, Man Q, Miao J, Xu W, Zheng Y, Zhou X, Gao Z
Journal of cell science 2022 Jul 1;135(13)
Journal of cell science 2022 Jul 1;135(13)
Spinal Cord Stimulation Alleviates Neuropathic Pain by Attenuating Microglial Activation via Reducing Colony-Stimulating Factor 1 Levels in the Spinal Cord in a Rat Model of Chronic Constriction Injury.
Sun C, Tao X, Wan C, Zhang X, Zhao M, Xu M, Wang P, Liu Y, Wang C, Xi Q, Song T
Anesthesia and analgesia 2022 Jul 1;135(1):178-190
Anesthesia and analgesia 2022 Jul 1;135(1):178-190
miR-1307-5p suppresses proliferation and tumorigenesis of bladder cancer via targeting MDM4 and the Hippo signaling pathway.
Huang W, Zhang C, Xiong S, Zhou X, Wang G, Guo J
Discover oncology 2022 Jul 1;13(1):57
Discover oncology 2022 Jul 1;13(1):57
Interleukin 7 inhibit autophagy via P53 regulated AMPK/mTOR signaling pathway in non-small cell lung cancer.
Zhu Y, Jiang X, Ding Z, Ming J
Scientific reports 2022 Jul 1;12(1):11208
Scientific reports 2022 Jul 1;12(1):11208
Molecular Subgroups of Intrahepatic Cholangiocarcinoma Discovered by Single-Cell RNA Sequencing-Assisted Multiomics Analysis.
Bao X, Li Q, Chen J, Chen D, Ye C, Dai X, Wang Y, Li X, Rong X, Cheng F, Jiang M, Zhu Z, Ding Y, Sun R, Liu C, Huang L, Jin Y, Li B, Lu J, Wu W, Guo Y, Fu W, Langley SR, Tano V, Fang W, Guo T, Sheng J, Zhao P, Ruan J
Cancer immunology research 2022 Jul 1;10(7):811-828
Cancer immunology research 2022 Jul 1;10(7):811-828
Extracts of Poria cocos improve functional dyspepsia via regulating brain-gut peptides, immunity and repairing of gastrointestinal mucosa.
Tu Y, Luo X, Liu D, Li H, Xia H, Ma C, Zhang D, Yang Y, Pan X, Wang T, Xia Y, Dan H, You P, Ye X
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Jan;95:153875
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Jan;95:153875
Protective effects of Huang-Lian-Jie-Du Decoction on diabetic nephropathy through regulating AGEs/RAGE/Akt/Nrf2 pathway and metabolic profiling in db/db mice.
Tang D, He WJ, Zhang ZT, Shi JJ, Wang X, Gu WT, Chen ZQ, Xu YH, Chen YB, Wang SM
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Jan;95:153777
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Jan;95:153777
Dysmyelination by Oligodendrocyte-Specific Ablation of Ninj2 Contributes to Depressive-Like Behaviors.
Sun Y, Chen X, Ou Z, Wang Y, Chen W, Zhao T, Liu C, Chen Y
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2022 Jan;9(3):e2103065
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2022 Jan;9(3):e2103065
Ciliary Type III Adenylyl Cyclase in the VMH Is Crucial for High-Fat Diet-Induced Obesity Mediated by Autophagy.
Yang D, Wu X, Wang W, Zhou Y, Wang Z
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2022 Jan;9(3):e2102568
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2022 Jan;9(3):e2102568
H. pylori CagA activates the NLRP3 inflammasome to promote gastric cancer cell migration and invasion.
Zhang X, Li C, Chen D, He X, Zhao Y, Bao L, Wang Q, Zhou J, Xie Y
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2022 Jan;71(1):141-155
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2022 Jan;71(1):141-155
Increased m6A-RNA methylation and FTO suppression is associated with myocardial inflammation and dysfunction during endotoxemia in mice.
Dubey PK, Patil M, Singh S, Dubey S, Ahuja P, Verma SK, Krishnamurthy P
Molecular and cellular biochemistry 2022 Jan;477(1):129-141
Molecular and cellular biochemistry 2022 Jan;477(1):129-141
PPARα agonist fenofibrate relieves acquired resistance to gefitinib in non-small cell lung cancer by promoting apoptosis via PPARα/AMPK/AKT/FoxO1 pathway.
Wang MS, Han QS, Jia ZR, Chen CS, Qiao C, Liu QQ, Zhang YM, Wang KW, Wang J, Xiao K, Ding XS
Acta pharmacologica Sinica 2022 Jan;43(1):167-176
Acta pharmacologica Sinica 2022 Jan;43(1):167-176
Autophagy regulates the cancer stem cell phenotype of head and neck squamous cell carcinoma through the noncanonical FOXO3/SOX2 axis.
Chen Y, Zhao H, Liang W, Jiang E, Zhou X, Shao Z, Liu K, Shang Z
Oncogene 2022 Jan;41(5):634-646
Oncogene 2022 Jan;41(5):634-646
Smoking-associated upregulation of CBX3 suppresses ARHGAP24 expression to activate Rac1 signaling and promote tumor progression in lung adenocarcinoma.
Jin X, Zhang B, Zhang H, Yu H
Oncogene 2022 Jan;41(4):538-549
Oncogene 2022 Jan;41(4):538-549
Disruption of the mouse Bmal1 locus promotes heterotopic ossification with aging via TGF-beta/BMP signaling.
Liang Q, Lu Y, Yu L, Zhu Q, Xie W, Wang Y, Ye L, Li Q, Liu S, Liu Y, Zhu C
Journal of bone and mineral metabolism 2022 Jan;40(1):40-55
Journal of bone and mineral metabolism 2022 Jan;40(1):40-55
CD93 a potential player in cytotrophoblast and endothelial cell migration.
Fantone S, Tossetta G, Di Simone N, Tersigni C, Scambia G, Marcheggiani F, Giannubilo SR, Marzioni D
Cell and tissue research 2022 Jan;387(1):123-130
Cell and tissue research 2022 Jan;387(1):123-130
Circular RNA circUSP13 sponges miR-29c to promote differentiation and inhibit apoptosis of goat myoblasts by targeting IGF1.
Zhang Z, Fan Y, Deng K, Liang Y, Zhang G, Gao X, El-Samahy MA, Zhang Y, Deng M, Wang F
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2022 Jan;36(1):e22097
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2022 Jan;36(1):e22097
CircRNA_01477 influences axonal growth via regulating miR-3075/FosB/Stat3 axis.
Qian X, Lin G, Wang J, Zhang S, Ma J, Yu B, Wu R, Liu M
Experimental neurology 2022 Jan;347:113905
Experimental neurology 2022 Jan;347:113905
Selective activation of cannabinoid receptor-2 reduces white matter injury via PERK signaling in a rat model of traumatic brain injury.
Li L, Luo Q, Shang B, Yang X, Zhang Y, Pan Q, Wu N, Tang W, Du D, Sun X, Jiang L
Experimental neurology 2022 Jan;347:113899
Experimental neurology 2022 Jan;347:113899
Inhibition of progesterone receptor membrane component-1 exacerbates neonatal hypoxic-ischemic cerebral damage in male mice.
Sun X, Hu Y, Zhou H, Wang S, Zhou C, Lin L, Zhu T, Ge J, Han J, Zhou Y, Jin G, Wang Y, Zu J, Shi H, Yang X, Zan K, Wang J, Hua F
Experimental neurology 2022 Jan;347:113893
Experimental neurology 2022 Jan;347:113893
Novel mutations of TYK2 leading to divergent clinical phenotypes.
Lv G, Sun G, Wu P, Du X, Zeng T, Wen W, Zhou L, An Y, Tang X, He T, Zhao X, Du H
Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology 2022 Jan;33(1):e13671
Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology 2022 Jan;33(1):e13671
Glycocalyx is critical for blood-brain barrier integrity by suppressing caveolin1-dependent endothelial transcytosis following ischemic stroke.
Zhu J, Li Z, Ji Z, Wu Y, He Y, Liu K, Chang Y, Peng Y, Lin Z, Wang S, Wang D, Huang K, Pan S
Brain pathology (Zurich, Switzerland) 2022 Jan;32(1):e13006
Brain pathology (Zurich, Switzerland) 2022 Jan;32(1):e13006
Bcl-2 hijacks the arsenic trioxide resistance in SH-SY5Y cells.
Wang J, Peng X, Yang D, Guo M, Xu X, Yin F, Wang Y, Huang J, Zhan L, Qi Z
Journal of cellular and molecular medicine 2022 Jan;26(2):563-569
Journal of cellular and molecular medicine 2022 Jan;26(2):563-569
IGF2BP3 promotes cell metastasis and is associated with poor patient survival in nasopharyngeal carcinoma.
Xu Y, Guo Z, Peng H, Guo L, Wang P
Journal of cellular and molecular medicine 2022 Jan;26(2):410-421
Journal of cellular and molecular medicine 2022 Jan;26(2):410-421
Caveolin-1 negatively regulates inflammation and fibrosis in silicosis.
He R, Yuan X, Lv X, Liu Q, Tao L, Meng J
Journal of cellular and molecular medicine 2022 Jan;26(1):99-107
Journal of cellular and molecular medicine 2022 Jan;26(1):99-107
Hepatitis B virus X mediates podocyte pyroptosis by regulating the ROS/NLRP3 signaling pathway in hepatitis B virus-associated glomerulonephritis.
Yu Y, Dong H, Sun J, Li B, Chen Y, Feng M, Yang X, Jiang W
Iranian journal of basic medical sciences 2022 Jan;25(1):103-109
Iranian journal of basic medical sciences 2022 Jan;25(1):103-109
Jolkinolide B alleviates renal fibrosis via anti-inflammation and inhibition of epithelial-mesenchymal transition in unilateral ureteral obstruction mice.
Li M, Yan Y, He J, Wang YM, Guo YX, Wang ZX, Zhang WK, Zhang HJ, Xu JK
Journal of Asian natural products research 2022 Jan;24(1):76-87
Journal of Asian natural products research 2022 Jan;24(1):76-87
Inhibition of DNA methyltransferase aberrations reinstates antioxidant aging suppressors and ameliorates renal aging.
Gao Q, Chen F, Zhang L, Wei A, Wang Y, Wu Z, Cao W
Aging cell 2022 Jan;21(1):e13526
Aging cell 2022 Jan;21(1):e13526
Morphological changes of macrophages and their potential contribution to tendon healing.
Yang QQ, Zhang L, Zhou YL, Tang JB
Colloids and surfaces. B, Biointerfaces 2022 Jan;209(Pt 1):112145
Colloids and surfaces. B, Biointerfaces 2022 Jan;209(Pt 1):112145
MICAL1 inhibits colorectal cancer cell migration and proliferation by regulating the EGR1/β-catenin signaling pathway.
Gu H, Li Y, Cui X, Cao H, Hou Z, Ti Y, Liu D, Gao J, Wang Y, Wen P
Biochemical pharmacology 2022 Jan;195:114870
Biochemical pharmacology 2022 Jan;195:114870
Dictamnine, a novel c-Met inhibitor, suppresses the proliferation of lung cancer cells by downregulating the PI3K/AKT/mTOR and MAPK signaling pathways.
Yu J, Zhang L, Peng J, Ward R, Hao P, Wang J, Zhang N, Yang Y, Guo X, Xiang C, An S, Xu TR
Biochemical pharmacology 2022 Jan;195:114864
Biochemical pharmacology 2022 Jan;195:114864
Maresin 1 protects against lipopolysaccharide/d-galactosamine-induced acute liver injury by inhibiting macrophage pyroptosis and inflammatory response.
Yang W, Tao K, Zhang P, Chen X, Sun X, Li R
Biochemical pharmacology 2022 Jan;195:114863
Biochemical pharmacology 2022 Jan;195:114863
Is platelet responsiveness to clopidogrel attenuated in overweight or obese patients and why? A reverse translational study in mice.
Jiang LP, Ji JZ, Ge PX, Zhu T, Mi QY, Tai T, Li YF, Xie HG
British journal of pharmacology 2022 Jan;179(1):46-64
British journal of pharmacology 2022 Jan;179(1):46-64
Silencing TXNIP ameliorates high uric acid-induced insulin resistance via the IRS2/AKT and Nrf2/HO-1 pathways in macrophages.
Yu W, Chen C, Zhuang W, Wang W, Liu W, Zhao H, Lv J, Xie D, Wang Q, He F, Xu C, Chen B, Yamamoto T, Koyama H, Cheng J
Free radical biology & medicine 2022 Jan;178:42-53
Free radical biology & medicine 2022 Jan;178:42-53
Pharmacological inhibition of IRAK1 and IRAK4 prevents endothelial inflammation and atherosclerosis in ApoE(-/-) mice.
Wu X, Xu M, Liu Z, Zhang Z, Liu Y, Luo S, Zheng X, Little PJ, Xu S, Weng J
Pharmacological research 2022 Jan;175:106043
Pharmacological research 2022 Jan;175:106043
Ghrelin alleviates 6-hydroxydopamine-induced neurotoxicity in SH-SY5Y cells.
He X, Yuan W, Yang CQ, Zhu L, Liu F, Feng J, Xue YX
Neural regeneration research 2022 Jan;17(1):170-177
Neural regeneration research 2022 Jan;17(1):170-177
Ubiquitin-specific peptidase 39 promotes human glioma cells migration and invasion by facilitating ADAM9 mRNA maturation.
Xiao Y, Ma W, Hu W, Di Q, Zhao X, Ma X, Chen X, Sun P, Wu H, Wu Z, Chen W
Molecular oncology 2022 Jan;16(2):388-404
Molecular oncology 2022 Jan;16(2):388-404
Isolation and characterization of secondary metabolites from the leaves of Sauropus spatulifolius Beille and their potential biological assays.
Li M, Cui Y, Zhu M, Huang X, Rehman FU, Wang J, Zhang L, Liu T, Liu J, Lu J, Jiang X, Zhang J
Fitoterapia 2022 Jan;156:105100
Fitoterapia 2022 Jan;156:105100
3-(3-Hydroxyphenyl)propionic acid, a microbial metabolite of quercetin, inhibits monocyte binding to endothelial cells via modulating E-selectin expression.
Feng J, Ge C, Li W, Li R
Fitoterapia 2022 Jan;156:105071
Fitoterapia 2022 Jan;156:105071
MACF1 promotes osteoblastic cell migration by regulating MAP1B through the GSK3beta/TCF7 pathway.
Su P, Tian Y, Yin C, Wang X, Li D, Yang C, Pei J, Deng X, King S, Li Y, Qian A
Bone 2022 Jan;154:116238
Bone 2022 Jan;154:116238
CD169-positive macrophages enhance abscopal effect of radiofrequency ablation therapy in liver cancer.
Song X, Li N, Liu Y, Wang Z, Wang T, Tan S, Li C, Qiu C, Gao L, Asano K, Tanaka M, Liang X, Liu X, Ma C
Translational oncology 2022 Jan;15(1):101306
Translational oncology 2022 Jan;15(1):101306
EIF1A depletion restrains human pituitary adenoma progression.
Geng R, Zhu X, Tao X, Liu J, Xu H
Translational oncology 2022 Jan;15(1):101299
Translational oncology 2022 Jan;15(1):101299
Dihydroartemisinin enhances the inhibitory effect of sorafenib on HepG2 cells by inducing ferroptosis and inhibiting energy metabolism.
Cui Z, Wang H, Li S, Qin T, Shi H, Ma J, Li L, Yu G, Jiang T, Li C
Journal of pharmacological sciences 2022 Jan;148(1):73-85
Journal of pharmacological sciences 2022 Jan;148(1):73-85
Effect of Fc-Elabela-21 on renal ischemia/reperfusion injury in mice: Mediation of anti-apoptotic effect via Akt phosphorylation.
Xu F, Wu M, Lu X, Zhang H, Shi L, Xi Y, Zhou H, Wang J, Miao L, Gong DW, Cui W
Peptides 2022 Jan;147:170682
Peptides 2022 Jan;147:170682
Synthesis compound XCR-7a ameliorates LPS-induced inflammatory response by inhibiting the phosphorylation of c-Fos.
Tang H, Roy P, Di Q, Ma X, Xiao Y, Wu Z, Quan J, Zhao J, Xiao W, Chen W
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Jan;145:112468
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Jan;145:112468
CAMKK2 Defines Ferroptosis Sensitivity of Melanoma Cells by Regulating AMPK‒NRF2 Pathway.
Wang S, Yi X, Wu Z, Guo S, Dai W, Wang H, Shi Q, Zeng K, Guo W, Li C
The Journal of investigative dermatology 2022 Jan;142(1):189-200.e8
The Journal of investigative dermatology 2022 Jan;142(1):189-200.e8
Luteolin alleviates ischemia/reperfusion injury-induced no-reflow by regulating Wnt/β-catenin signaling in rats.
Qin X, Qin H, Li Z, Xue S, Huang B, Liu X, Wang D
Microvascular research 2022 Jan;139:104266
Microvascular research 2022 Jan;139:104266
Impaired vessel relaxation response and increased infarct size in smooth muscle cannabinoid receptor 1 knockout mice.
Wang LN, Xing MD, Qu WT, Wang CB, Liu ZQ, Han J, Ren W, Qiao YN
Microvascular research 2022 Jan;139:104263
Microvascular research 2022 Jan;139:104263
Minimally modified low-density lipoprotein upregulates mouse mesenteric arterial 5-HT(1B) receptor in vivo via activation of the JAK2/STAT3 pathway.
Tang HX, Lin J, Xu CB, Chen G, Liao YJ, Lei NR, Li J
Microvascular research 2022 Jan;139:104260
Microvascular research 2022 Jan;139:104260
Overexpression of DOCK6 in oral squamous cell cancer promotes cellular migration and invasion and is associated with poor prognosis.
Zhang ZY, Sun YY, Wang HC, Fu WN, Sun CF
Archives of oral biology 2022 Jan;133:105297
Archives of oral biology 2022 Jan;133:105297
Icaritin alleviates docetaxel-induced skin injury by suppressing reactive oxygen species via estrogen receptors.
Zou J, Xu MX, Li F, Wang YH, Li XQ, Yu DJ, Ma YJ, Zhang YY, Sun XD
Thoracic cancer 2022 Jan;13(2):190-201
Thoracic cancer 2022 Jan;13(2):190-201
cGAS guards against chromosome end-to-end fusions during mitosis and facilitates replicative senescence.
Li X, Li X, Xie C, Cai S, Li M, Jin H, Wu S, Cui J, Liu H, Zhao Y
Protein & cell 2022 Jan;13(1):47-64
Protein & cell 2022 Jan;13(1):47-64
Long noncoding RNA UBA6-AS1 inhibits the malignancy of ovarian cancer cells via suppressing the decay of UBA6 mRNA.
Wang Y, Chen Z
Bioengineered 2022 Jan;13(1):178-189
Bioengineered 2022 Jan;13(1):178-189
Metformin promotes histone deacetylation of optineurin and suppresses tumour growth through autophagy inhibition in ocular melanoma.
Zhuang A, Chai P, Wang S, Zuo S, Yu J, Jia S, Ge S, Jia R, Zhou Y, Shi W, Xu X, Ruan J, Fan X
Clinical and translational medicine 2022 Jan;12(1):e660
Clinical and translational medicine 2022 Jan;12(1):e660
Extracellular vesicle-mediated delivery of circDYM alleviates CUS-induced depressive-like behaviours.
Yu X, Bai Y, Han B, Ju M, Tang T, Shen L, Li M, Yang L, Zhang Z, Hu G, Chao J, Zhang Y, Yao H
Journal of extracellular vesicles 2022 Jan;11(1):e12185
Journal of extracellular vesicles 2022 Jan;11(1):e12185
Overexpression of DUOX2 mediates doxorubicin resistance and predicts prognosis of pancreatic cancer.
Lyu PW, Xu XD, Zong K, Qiu XG
Gland surgery 2022 Jan;11(1):115-124
Gland surgery 2022 Jan;11(1):115-124
β-Hydroxybutyrate impairs neutrophil migration distance through activation of a protein kinase C and myosin light chain 2 signaling pathway in ketotic cows.
Song Y, Yang Y, Zeng W, Loor JJ, Jiang Q, Peng Z, Li Y, Jiang S, Feng X, Du X, Li X, Liu G
Journal of dairy science 2022 Jan;105(1):761-771
Journal of dairy science 2022 Jan;105(1):761-771
Bioglass promotes wound healing by inhibiting endothelial cell pyroptosis through regulation of the connexin 43/reactive oxygen species (ROS) signaling pathway.
Zhang K, Chai B, Ji H, Chen L, Ma Y, Zhu L, Xu J, Wu Y, Lan Y, Li H, Feng Z, Xiao J, Zhang H, Xu K
Laboratory investigation; a journal of technical methods and pathology 2022 Jan;102(1):90-101
Laboratory investigation; a journal of technical methods and pathology 2022 Jan;102(1):90-101
TNFSF9 promotes metastasis of pancreatic cancer by regulating M2 polarization of macrophages through Src/FAK/p-Akt/IL-1β signaling.
Wu J, Wang Y, Yang Y, Liu F, Jiang Z, Jiang Z
International immunopharmacology 2022 Jan;102:108429
International immunopharmacology 2022 Jan;102:108429
Artesunate attenuates atherosclerosis by inhibiting macrophage M1-like polarization and improving metabolism.
Wang X, Du H, Li X
International immunopharmacology 2022 Jan;102:108413
International immunopharmacology 2022 Jan;102:108413
Exosomal myeloperoxidase as a biomarker of deep venous thrombosis.
Han Y, Bai X, Wang X
Annals of translational medicine 2022 Jan;10(1):9
Annals of translational medicine 2022 Jan;10(1):9
Clerodane diterpene induces apoptosis/anoikis and suppresses migration and invasion of human bladder cancer cells through the histone deacetylases, integrin-focal adhesion kinase, and matrix metalloproteinase 9 signalling pathways.
Chen YC, Chen CI, Chang CY, Huang BM, Chen YC
Human & experimental toxicology 2022 Jan-Dec;41:9603271221143040
Human & experimental toxicology 2022 Jan-Dec;41:9603271221143040
Curculigoside mitigates hepatic ischemia/reperfusion-induced oxidative stress, inflammation, and apoptosis via activation of the Nrf-2/HO-1 pathway.
Du P, Zhang X, Luo K, Li Y, Fu C, Xiao J, Xiao Q
Human & experimental toxicology 2022 Jan-Dec;41:9603271221087146
Human & experimental toxicology 2022 Jan-Dec;41:9603271221087146
Effects of butein on human osteosarcoma cell proliferation, apoptosis, and autophagy through oxidative stress.
Zhang P, Zhang J, Quan H, Chen P, Wang J, Liang Y
Human & experimental toxicology 2022 Jan-Dec;41:9603271221074346
Human & experimental toxicology 2022 Jan-Dec;41:9603271221074346
G-protein Coupled Receptor 34 Promotes Gliomagenesis by Inducing Proliferation and Malignant Phenotype via TGF-Beta/Smad Signaling Pathway.
Cheng Y, Heng X, Feng F
Technology in cancer research & treatment 2022 Jan-Dec;21:15330338221105733
Technology in cancer research & treatment 2022 Jan-Dec;21:15330338221105733
Vascular endothelial growth factor-A/vascular endothelial growth factor2 signaling in spinal neurons contributes to bone cancer pain.
Fan LJ, Kan HM, Chen XT, Sun YY, Chen LP, Shen W
Molecular pain 2022 Jan-Dec;18:17448069221075891
Molecular pain 2022 Jan-Dec;18:17448069221075891
ROS/PI3K/Akt and Wnt/β-catenin signalings activate HIF-1α-induced metabolic reprogramming to impart 5-fluorouracil resistance in colorectal cancer.
Dong S, Liang S, Cheng Z, Zhang X, Luo L, Li L, Zhang W, Li S, Xu Q, Zhong M, Zhu J, Zhang G, Hu S
Journal of experimental & clinical cancer research : CR 2022 Jan 8;41(1):15
Journal of experimental & clinical cancer research : CR 2022 Jan 8;41(1):15
EndMT: New findings on the origin of myofibroblasts in endometrial fibrosis of intrauterine adhesions.
Xu C, Bao M, Fan X, Huang J, Zhu C, Xia W
Reproductive biology and endocrinology : RB&E 2022 Jan 7;20(1):9
Reproductive biology and endocrinology : RB&E 2022 Jan 7;20(1):9
Endothelial cell metabolic memory causes cardiovascular dysfunction in diabetes.
Yao Y, Song Q, Hu C, Da X, Yu Y, He Z, Xu C, Chen Q, Wang QK
Cardiovascular research 2022 Jan 7;118(1):196-211
Cardiovascular research 2022 Jan 7;118(1):196-211
AHSA1 is a promising therapeutic target for cellular proliferation and proteasome inhibitor resistance in multiple myeloma.
Gu C, Wang Y, Zhang L, Qiao L, Sun S, Shao M, Tang X, Ding P, Tang C, Cao Y, Zhou Y, Guo M, Wei R, Li N, Xiao Y, Duan J, Yang Y
Journal of experimental & clinical cancer research : CR 2022 Jan 6;41(1):11
Journal of experimental & clinical cancer research : CR 2022 Jan 6;41(1):11
Annexin A1 promotes the progression of bladder cancer via regulating EGFR signaling pathway.
Li P, Li L, Li Z, Wang S, Li R, Zhao W, Feng Y, Huang S, Li L, Qiu H, Xia S
Cancer cell international 2022 Jan 6;22(1):7
Cancer cell international 2022 Jan 6;22(1):7
CRISPR/Cas9 delivery by NIR-responsive biomimetic nanoparticles for targeted HBV therapy.
Wang D, Chen L, Li C, Long Q, Yang Q, Huang A, Tang H
Journal of nanobiotechnology 2022 Jan 6;20(1):27
Journal of nanobiotechnology 2022 Jan 6;20(1):27
MiR-30c-5p loss-induced PELI1 accumulation regulates cell proliferation and migration via activating PI3K/AKT pathway in papillary thyroid carcinoma.
Zheng T, Zhou Y, Xu X, Qi X, Liu J, Pu Y, Zhang S, Gao X, Luo X, Li M, Wang X, Dong L, Wang Y, Mao C
Journal of translational medicine 2022 Jan 6;20(1):20
Journal of translational medicine 2022 Jan 6;20(1):20
Trans-cinnamaldehyde suppresses microtubule detyrosination and alleviates cardiac hypertrophy.
Tian J, Shan XL, Wang SN, Chen HH, Zhao P, Qian DD, Xu M, Guo W, Zhang C, Lu R
European journal of pharmacology 2022 Jan 5;914:174687
European journal of pharmacology 2022 Jan 5;914:174687
Cisplatin induces damage of auditory cells: Possible relation with dynamic variation in calcium homeostasis and responding channels.
Zhao H, Xu Y, Song X, Zhang Q, Wang Y, Yin H, Bai X, Li J
European journal of pharmacology 2022 Jan 5;914:174662
European journal of pharmacology 2022 Jan 5;914:174662
Protective role of m(6)A binding protein YTHDC2 on CCNB2 in manganese-induced spermatogenesis dysfunction.
Qi Z, Liu Y, Yang H, Yang X, Wang H, Liu B, Yuan Y, Wang G, Xu B, Liu W, Xu Z, Deng Y
Chemico-biological interactions 2022 Jan 5;351:109754
Chemico-biological interactions 2022 Jan 5;351:109754
Immunomodulatory Effect of Serum Exosomes From Crohn Disease on Macrophages via Let-7b-5p/TLR4 Signaling.
Gong L, Xiao J, Yi J, Xiao J, Lu F, Liu X
Inflammatory bowel diseases 2022 Jan 5;28(1):96-108
Inflammatory bowel diseases 2022 Jan 5;28(1):96-108
Heat Shock Protein 60 Restricts Release of Mitochondrial dsRNA to Suppress Hepatic Inflammation and Ameliorate Non-Alcoholic Fatty Liver Disease in Mice.
Huang YH, Wang FS, Wang PW, Lin HY, Luo SD, Yang YL
International journal of molecular sciences 2022 Jan 5;23(1)
International journal of molecular sciences 2022 Jan 5;23(1)
A novel ICG-labeled cyclic TMTP1 peptide dimer for sensitive tumor imaging and enhanced photothermal therapy in vivo.
Wang L, Zhang D, Li J, Li F, Wei R, Jiang G, Xu H, Wang X, Zhou Y, Xi L
European journal of medicinal chemistry 2022 Jan 5;227:113935
European journal of medicinal chemistry 2022 Jan 5;227:113935
STING orchestrates the crosstalk between polyunsaturated fatty acid metabolism and inflammatory responses.
Vila IK, Chamma H, Steer A, Saccas M, Taffoni C, Turtoi E, Reinert LS, Hussain S, Marines J, Jin L, Bonnefont X, Hubert M, Schwartz O, Paludan SR, Van Simaeys G, Doumont G, Sobhian B, Vlachakis D, Turtoi A, Laguette N
Cell metabolism 2022 Jan 4;34(1):125-139.e8
Cell metabolism 2022 Jan 4;34(1):125-139.e8
SIRT6 protects vascular smooth muscle cells from osteogenic transdifferentiation via Runx2 in chronic kidney disease.
Li W, Feng W, Su X, Luo D, Li Z, Zhou Y, Zhu Y, Zhang M, Chen J, Liu B, Huang H
The Journal of clinical investigation 2022 Jan 4;132(1)
The Journal of clinical investigation 2022 Jan 4;132(1)
Enteromorpha prolifera polysaccharide-zinc complex modulates the immune response and alleviates LPS-induced intestinal inflammation via inhibiting the TLR4/NF-κB signaling pathway.
Zhang Y, Duan X, Wassie T, Wang HH, Li T, Xie C, Wu X
Food & function 2022 Jan 4;13(1):52-63
Food & function 2022 Jan 4;13(1):52-63
Steatosis induced by nonylphenol in HepG2 cells and the intervention effect of curcumin.
Shan D, Wang J, Di Q, Jiang Q, Xu Q
Food & function 2022 Jan 4;13(1):327-343
Food & function 2022 Jan 4;13(1):327-343
ACSL4 Directs Intramuscular Adipogenesis and Fatty Acid Composition in Pigs.
Ren H, Zhang H, Hua Z, Zhu Z, Tao J, Xiao H, Zhang L, Bi Y, Wang H
Animals : an open access journal from MDPI 2022 Jan 4;12(1)
Animals : an open access journal from MDPI 2022 Jan 4;12(1)
mTOR inhibitor improves testosterone-induced myocardial hypertrophy in hypertensive rats.
Chen J, Yu J, Yuan R, Li N, Li C, Zhang X
The Journal of endocrinology 2022 Jan 31;252(3):179-193
The Journal of endocrinology 2022 Jan 31;252(3):179-193
MiR-29a Curbs Hepatocellular Carcinoma Incidence via Targeting of HIF-1α and ANGPT2.
Huang YH, Lian WS, Wang FS, Wang PW, Lin HY, Tsai MC, Yang YL
International journal of molecular sciences 2022 Jan 31;23(3)
International journal of molecular sciences 2022 Jan 31;23(3)
m6A modifications regulate intestinal immunity and rotavirus infection.
Wang A, Tao W, Tong J, Gao J, Wang J, Hou G, Qian C, Zhang G, Li R, Wang D, Ren X, Zhang K, Ding S, Flavell RA, Li H, Pan W, Zhu S
eLife 2022 Jan 31;11
eLife 2022 Jan 31;11
Renoprotective activity of Ribes diacanthum pall (RDP) against inflammation in cisplatin-stimulated mice model and human renal tubular epithelial cells.
Wu Y, Zhao L, Gu L, Tilyek A, Yu B, Chai C
Journal of ethnopharmacology 2022 Jan 30;283:114696
Journal of ethnopharmacology 2022 Jan 30;283:114696
Protective effect of oligosaccharides isolated from Panax ginseng C. A. Meyer against UVB-induced skin barrier damage in BALB/c hairless mice and human keratinocytes.
Li Z, Jiang R, Jing C, Liu J, Xu X, Sun L, Zhao D
Journal of ethnopharmacology 2022 Jan 30;283:114677
Journal of ethnopharmacology 2022 Jan 30;283:114677
CHMP2B regulates TDP-43 phosphorylation and cytotoxicity independent of autophagy via CK1.
Deng X, Sun X, Yue W, Duan Y, Hu R, Zhang K, Ni J, Cui J, Wang Q, Chen Y, Li A, Fang Y
The Journal of cell biology 2022 Jan 3;221(1)
The Journal of cell biology 2022 Jan 3;221(1)
Hyaluronic Acid-Modified Nanoparticles Self-Assembled from Linoleic Acid-Conjugated Chitosan for the Codelivery of miR34a and Doxorubicin in Resistant Breast Cancer.
Yang X, Shang P, Ji J, Malichewe C, Yao Z, Liao J, Du D, Sun C, Wang L, Tang YJ, Guo X
Molecular pharmaceutics 2022 Jan 3;19(1):2-17
Molecular pharmaceutics 2022 Jan 3;19(1):2-17
Long non-coding RNA lncC11orf54-1 modulates neuroinflammatory responses by activating NF-κB signaling during meningitic Escherichia coli infection.
Xu B, Yang R, Yang B, Li L, Chen J, Fu J, Qu X, Huo D, Tan C, Chen H, Peng Z, Wang X
Molecular brain 2022 Jan 3;15(1):4
Molecular brain 2022 Jan 3;15(1):4
Islet amyloid polypeptide cross-seeds tau and drives the neurofibrillary pathology in Alzheimer's disease.
Zhang G, Meng L, Wang Z, Peng Q, Chen G, Xiong J, Zhang Z
Molecular neurodegeneration 2022 Jan 29;17(1):12
Molecular neurodegeneration 2022 Jan 29;17(1):12
Hsa_circ_0076931 suppresses malignant biological properties, down-regulates miR-6760-3p through direct binding, and up-regulates CCBE1 in glioma.
Ke Y, Su S, Duan C, Wang Y, Cao G, Fang Z, Tuo Y, Li W, Wang Z, Zhang S
Bioscience reports 2022 Jan 28;42(1)
Bioscience reports 2022 Jan 28;42(1)
Functional Characterization of FH Mutation c.557G>A Underlies Uterine Leiomyomas.
Li P, Wu Y, Wu H, Xiong Q, Zhao N, Chen G, Wu C, Xiao H
International journal of molecular sciences 2022 Jan 27;23(3)
International journal of molecular sciences 2022 Jan 27;23(3)
Lipid Droplets Are Beneficial for Rabies Virus Replication by Facilitating Viral Budding.
Zhao J, Zeng Z, Chen Y, Liu W, Chen H, Fu ZF, Zhao L, Zhou M
Journal of virology 2022 Jan 26;96(2):e0147321
Journal of virology 2022 Jan 26;96(2):e0147321
Loss of miR-31-5p drives hematopoietic stem cell malignant transformation and restoration eliminates leukemia stem cells in mice.
Zhu B, Zhong W, Cao X, Pan G, Xu M, Zheng J, Chen H, Feng X, Luo C, Lu C, Xiao J, Lin W, Lai C, Li M, Du X, Yi Q, Yan D
Science translational medicine 2022 Jan 26;14(629):eabh2548
Science translational medicine 2022 Jan 26;14(629):eabh2548
The Role of Sirtuin 1 in Palmitic Acid-Induced Endoplasmic Reticulum Stress in Cardiac Myoblasts.
Yang HY, Chen JY, Huo YN, Yu PL, Lin PZ, Hsu SC, Huang SM, Tsai CS, Lin CY
Life (Basel, Switzerland) 2022 Jan 26;12(2)
Life (Basel, Switzerland) 2022 Jan 26;12(2)
Non-viral siRNA transfection of primary mesenchymal stromal cells (MSCs): Assessment of tyrosine-modified PEI and PPI efficacy and biocompatibility.
Noske S, Karimov M, Hansen M, Zatula N, Ewe A, Aigner A
International journal of pharmaceutics 2022 Jan 25;612:121359
International journal of pharmaceutics 2022 Jan 25;612:121359
Upregulation of CENPM facilitates lung adenocarcinoma progression via PI3K/AKT/mTOR signaling pathway.
Liu C, Wang Y, Dao Y, Wang S, Hou F, Yang Z, Liu P, Lv J, Lv L, Li G, Zhou Y, Deng Z
Acta biochimica et biophysica Sinica 2022 Jan 25;54(1):99-112
Acta biochimica et biophysica Sinica 2022 Jan 25;54(1):99-112
Diffuse large B-cell lymphoma-derived exosomes push macrophage polarization toward M2 phenotype via GP130/STAT3 signaling pathway.
Ling HY, Yang Z, Wang PJ, Sun Y, Ju SG, Li J, Fu JX
Chemico-biological interactions 2022 Jan 25;352:109779
Chemico-biological interactions 2022 Jan 25;352:109779
SNX27 suppresses SARS-CoV-2 infection by inhibiting viral lysosome/late endosome entry.
Yang B, Jia Y, Meng Y, Xue Y, Liu K, Li Y, Liu S, Li X, Cui K, Shang L, Cheng T, Zhang Z, Hou Y, Yang X, Yan H, Duan L, Tong Z, Wu C, Liu Z, Gao S, Zhuo S, Huang W, Gao GF, Qi J, Shang G
Proceedings of the National Academy of Sciences of the United States of America 2022 Jan 25;119(4)
Proceedings of the National Academy of Sciences of the United States of America 2022 Jan 25;119(4)
Parkinson's disease protein PARK7 prevents metabolite and protein damage caused by a glycolytic metabolite.
Heremans IP, Caligiore F, Gerin I, Bury M, Lutz M, Graff J, Stroobant V, Vertommen D, Teleman AA, Van Schaftingen E, Bommer GT
Proceedings of the National Academy of Sciences of the United States of America 2022 Jan 25;119(4)
Proceedings of the National Academy of Sciences of the United States of America 2022 Jan 25;119(4)
Golgi phosphoprotein 3 promotes angiogenesis and sorafenib resistance in hepatocellular carcinoma via upregulating exosomal miR-494-3p.
Gao Y, Yin Z, Qi Y, Peng H, Ma W, Wang R, Li W
Cancer cell international 2022 Jan 24;22(1):35
Cancer cell international 2022 Jan 24;22(1):35
N6-Methyladenosine Modification of CDH1 mRNA Promotes PM2.5-Induced Pulmonary Fibrosis via Mediating Epithelial Mesenchymal Transition.
Ning J, Du H, Zhang Y, Liu Q, Jiang T, Pang Y, Tian X, Yan L, Niu Y, Zhang R
Toxicological sciences : an official journal of the Society of Toxicology 2022 Jan 24;185(2):143-157
Toxicological sciences : an official journal of the Society of Toxicology 2022 Jan 24;185(2):143-157
WASH interacts with Ku to regulate DNA double-stranded break repair.
Wang T, Du XH, Hong Y, Hong X, Fan L, Zhou JW, Sun H, Ge J, Billadeau DD, Deng ZH
iScience 2022 Jan 21;25(1):103676
iScience 2022 Jan 21;25(1):103676
HERC3 regulates epithelial-mesenchymal transition by directly ubiquitination degradation EIF5A2 and inhibits metastasis of colorectal cancer.
Zhang Z, He G, Lv Y, Liu Y, Niu Z, Feng Q, Hu R, Xu J
Cell death & disease 2022 Jan 21;13(1):74
Cell death & disease 2022 Jan 21;13(1):74
N6-methyladenosine demethylase FTO promotes growth and metastasis of gastric cancer via m(6)A modification of caveolin-1 and metabolic regulation of mitochondrial dynamics.
Zhou Y, Wang Q, Deng H, Xu B, Zhou Y, Liu J, Liu Y, Shi Y, Zheng X, Jiang J
Cell death & disease 2022 Jan 21;13(1):72
Cell death & disease 2022 Jan 21;13(1):72
Phosphodiesterase 4D promotes angiotensin II-induced hypertension in mice via smooth muscle cell contraction.
Fan T, Hou Y, Ge W, Fan T, Feng X, Guo W, Song X, Gao R, Wang J
Communications biology 2022 Jan 20;5(1):81
Communications biology 2022 Jan 20;5(1):81
An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.
Zhang Y, Shang L, Zhang J, Liu Y, Jin C, Zhao Y, Lei X, Wang W, Xiao X, Zhang X, Liu Y, Liu L, Zhuang MW, Mi Q, Tian C, Wang J, He F, Wang PH, Wang J
Cell chemical biology 2022 Jan 20;29(1):5-18.e6
Cell chemical biology 2022 Jan 20;29(1):5-18.e6
Epimedium protects against dyszoospermia in mice with Pex3 knockout by exerting antioxidant effects and regulating the expression level of P16.
Zhao H, Zhao T, Yang J, Huang Q, Wu H, Pan Y, Wang H, Qian Y
Cell death & disease 2022 Jan 20;13(1):69
Cell death & disease 2022 Jan 20;13(1):69
DDX39B contributes to the proliferation of colorectal cancer through direct binding to CDK6/CCND1.
Zhang H, He C, Guo X, Fang Y, Lai Q, Wang X, Pan X, Li H, Qin K, Li A, Liu S, Li Q
Cell death discovery 2022 Jan 19;8(1):30
Cell death discovery 2022 Jan 19;8(1):30
Lipid reprogramming induced by the TFEB-ERRα axis enhanced membrane fluidity to promote EC progression.
Mao X, Lei H, Yi T, Su P, Tang S, Tong Y, Dong B, Ruan G, Mustea A, Sehouli J, Sun P
Journal of experimental & clinical cancer research : CR 2022 Jan 19;41(1):28
Journal of experimental & clinical cancer research : CR 2022 Jan 19;41(1):28
Discovery of a Covalent FEM1B Recruiter for Targeted Protein Degradation Applications.
Henning NJ, Manford AG, Spradlin JN, Brittain SM, Zhang E, McKenna JM, Tallarico JA, Schirle M, Rape M, Nomura DK
Journal of the American Chemical Society 2022 Jan 19;144(2):701-708
Journal of the American Chemical Society 2022 Jan 19;144(2):701-708
Overexpression of Twist1 in vascular endothelial cells promotes pathological retinal angiogenesis in mice.
Zhang L, Zhang SS, Wang KF, Li YH, Xu HJ, Sun KX, Ma S, Leng HM, Chen SZ, Jia WJ, Zhu XJ, Li J
Zoological research 2022 Jan 18;43(1):64-74
Zoological research 2022 Jan 18;43(1):64-74
Metastasis enhancer PGRMC1 boosts store-operated Ca(2+) entry by uncoiling Ca(2+) sensor STIM1 for focal adhesion turnover and actomyosin formation.
Lee SK, Kweon YC, Lee AR, Lee YY, Park CY
Cell reports 2022 Jan 18;38(3):110281
Cell reports 2022 Jan 18;38(3):110281
Canonical WNT pathway inhibition reduces ATP synthesis rates in glioblastoma stem cells.
Ouwens DM, Hewera M, Li G, Di W, Muhammad S, Hänggi D, Steiger HJ, Dumitru CA, Sandalcioglu E, Croner RS, Zhang W, Kakhlon O, Kahlert UD
Frontiers in bioscience (Landmark edition) 2022 Jan 18;27(1):35
Frontiers in bioscience (Landmark edition) 2022 Jan 18;27(1):35
Ferroptosis-related lncRNA pairs to predict the clinical outcome and molecular characteristics of pancreatic ductal adenocarcinoma.
Tang R, Wu Z, Rong Z, Xu J, Wang W, Zhang B, Yu X, Shi S
Briefings in bioinformatics 2022 Jan 17;23(1)
Briefings in bioinformatics 2022 Jan 17;23(1)
4D-quantitative proteomics signature of asthenozoospermia and identification of extracellular matrix protein 1 as a novel biomarker for sperm motility.
Yang J, Liu Q, Yu B, Han B, Yang B
Molecular omics 2022 Jan 17;18(1):83-91
Molecular omics 2022 Jan 17;18(1):83-91
The histone methyltransferase DOT1L is a new epigenetic regulator of pulmonary fibrosis.
Yang D, Xu P, Su H, Zhong W, Xu J, Su Z, Liu X
Cell death & disease 2022 Jan 17;13(1):60
Cell death & disease 2022 Jan 17;13(1):60
LncRNA SNHG16 accelerates atherosclerosis and promotes ox-LDL-induced VSMC growth via the miRNA-22-3p/HMGB2 axis.
Wang Y, Yang Y, Zhang T, Jia S, Ma X, Zhang M, Wang L, Ma A
European journal of pharmacology 2022 Jan 15;915:174601
European journal of pharmacology 2022 Jan 15;915:174601
Salidroside alleviates oxidative stress and apoptosis via AMPK/Nrf2 pathway in DHT-induced human granulosa cell line KGN.
Ji R, Jia FY, Chen X, Wang ZH, Jin WY, Yang J
Archives of biochemistry and biophysics 2022 Jan 15;715:109094
Archives of biochemistry and biophysics 2022 Jan 15;715:109094
C9orf72 knockdown alleviates hepatic insulin resistance by promoting lipophagy.
Cang X, Wang Y, Zeng J, Gao J, Yu Q, Lu C, Xu F, Lin J, Zhu J, Wang X
Biochemical and biophysical research communications 2022 Jan 15;588:15-22
Biochemical and biophysical research communications 2022 Jan 15;588:15-22
Iron overload inhibits cell proliferation and promotes autophagy via PARP1/SIRT1 signaling in endometriosis and adenomyosis.
Zhou Y, Zhao X, Zhang L, Xia Q, Peng Y, Zhang H, Yan D, Yang Z, Li J
Toxicology 2022 Jan 15;465:153050
Toxicology 2022 Jan 15;465:153050
Kinesin family member 23 exerts a protumor function in breast cancer via stimulation of the Wnt/β-catenin pathway.
He X, Wang J, Zhou R, Yu S, Jiang J, Zhou Q
Toxicology and applied pharmacology 2022 Jan 15;435:115834
Toxicology and applied pharmacology 2022 Jan 15;435:115834
BDE-47 induced PC-12 cell differentiation via TrkA downstream pathways and caused the loss of hippocampal neurons in BALB/c mice.
Liu D, Xue D, Lu W, Yang Z, Li L, Xia B, Wei J, Chen X, Yang Y, Wang X, Lin G
Journal of hazardous materials 2022 Jan 15;422:126850
Journal of hazardous materials 2022 Jan 15;422:126850
Genome-wide CRISPR/Cas9 library screen identifies PCMT1 as a critical driver of ovarian cancer metastasis.
Zhang J, Li Y, Liu H, Zhang J, Wang J, Xia J, Zhang Y, Yu X, Ma J, Huang M, Wang J, Wang L, Li Q, Cui R, Yang W, Xu Y, Feng W
Journal of experimental & clinical cancer research : CR 2022 Jan 15;41(1):24
Journal of experimental & clinical cancer research : CR 2022 Jan 15;41(1):24
Weakened interaction of ATG14 and the SNARE complex blocks autophagosome-lysosome fusion contributes to fluoride-induced developmental neurotoxicity.
Zhang Y, Han X, Tang Y, Zhang J, Hu Z, Xu W, Yao P, Niu Q
Ecotoxicology and environmental safety 2022 Jan 15;230:113108
Ecotoxicology and environmental safety 2022 Jan 15;230:113108
In vivo assessment of molybdenum and cadmium co-induce nephrotoxicity via causing calcium homeostasis disorder and autophagy in ducks (Anas platyrhyncha).
Zhang C, Lin T, Nie G, Hu R, Pi S, Wei Z, Wang C, Li G, Hu G
Ecotoxicology and environmental safety 2022 Jan 15;230:113099
Ecotoxicology and environmental safety 2022 Jan 15;230:113099
Congenital cataract-causing mutation βB1-L116P is prone to amyloid fibrils aggregation and protease degradation with low structural stability.
Liu J, Xu W, Wang K, Chen F, Ren L, Xu J, Yao K, Chen X
International journal of biological macromolecules 2022 Jan 15;195:475-482
International journal of biological macromolecules 2022 Jan 15;195:475-482
Protective effects of polysaccharides from Atractylodes macrocephalae Koidz. against dextran sulfate sodium induced intestinal mucosal injury on mice.
Kai L, Zong X, Jiang Q, Lu Z, Wang F, Wang Y, Wang T, Jin M
International journal of biological macromolecules 2022 Jan 15;195:142-151
International journal of biological macromolecules 2022 Jan 15;195:142-151
Inhibition of Rac1 attenuates radiation-induced lung injury while suppresses lung tumor in mice.
An N, Li Z, Yan X, Zhao H, Yang Y, Liu R, Yang Y, Gao F, Li B, Liu H, Yuan H
Cell death discovery 2022 Jan 14;8(1):26
Cell death discovery 2022 Jan 14;8(1):26
Discovery of Orally Available Retinoic Acid Receptor-Related Orphan Receptor γ-t/Dihydroorotate Dehydrogenase Dual Inhibitors for the Treatment of Refractory Inflammatory Bowel Disease.
Chen JA, Ma H, Liu Z, Tian J, Lu S, Fang W, Ze S, Lu W, Xie Q, Huang J, Wang Y
Journal of medicinal chemistry 2022 Jan 13;65(1):592-615
Journal of medicinal chemistry 2022 Jan 13;65(1):592-615
Small Heat Shock Protein 22 Improves Cognition and Learning in the Tauopathic Brain.
Rodriguez Ospina S, Blazier DM, Criado-Marrero M, Gould LA, Gebru NT, Beaulieu-Abdelahad D, Wang X, Remily-Wood E, Chaput D, Stevens S, Uversky VN, Bickford PC, Dickey CA, Blair LJ
International journal of molecular sciences 2022 Jan 13;23(2)
International journal of molecular sciences 2022 Jan 13;23(2)
Sea Cucumber Peptides Attenuated the Scopolamine-Induced Memory Impairment in Mice and Rats and the Underlying Mechanism.
Lu Z, Xu X, Li D, Sun N, Lin S
Journal of agricultural and food chemistry 2022 Jan 12;70(1):157-170
Journal of agricultural and food chemistry 2022 Jan 12;70(1):157-170
Control of Expression of Key Cell Cycle Enzymes Drives Cell Line-Specific Functions of CDK7 in Human PDAC Cells.
Kolloch L, Kreinest T, Meisterernst M, Oeckinghaus A
International journal of molecular sciences 2022 Jan 12;23(2)
International journal of molecular sciences 2022 Jan 12;23(2)
Deficiency of two-pore segment channel 2 contributes to systemic lupus erythematosus via regulation of apoptosis and cell cycle.
Li K, Xu J, Xue K, Yu R, Li C, Fei W, Ning X, Han Y, Wang Z, Shu J, Cui Y
Chinese medical journal 2022 Jan 12;135(4):447-455
Chinese medical journal 2022 Jan 12;135(4):447-455
New IMB16-4 Nanoparticles Improved Oral Bioavailability and Enhanced Anti-Hepatic Fibrosis on Rats.
Niu X, Wang X, Niu B, Wang Y, He H, Li G
Pharmaceuticals (Basel, Switzerland) 2022 Jan 11;15(1)
Pharmaceuticals (Basel, Switzerland) 2022 Jan 11;15(1)
Linc01133 contributes to gastric cancer growth by enhancing YES1-dependent YAP1 nuclear translocation via sponging miR-145-5p.
Sun Y, Tian Y, He J, Tian Y, Zhang G, Zhao R, Zhu WJ, Gao P
Cell death & disease 2022 Jan 11;13(1):51
Cell death & disease 2022 Jan 11;13(1):51
Gut microbiota promotes cholesterol gallstone formation by modulating bile acid composition and biliary cholesterol secretion.
Hu H, Shao W, Liu Q, Liu N, Wang Q, Xu J, Zhang X, Weng Z, Lu Q, Jiao L, Chen C, Sun H, Jiang Z, Zhang X, Gu A
Nature communications 2022 Jan 11;13(1):252
Nature communications 2022 Jan 11;13(1):252
Aging is associated with increased brain iron through cortex-derived hepcidin expression.
Sato T, Shapiro JS, Chang HC, Miller RA, Ardehali H
eLife 2022 Jan 11;11
eLife 2022 Jan 11;11
Cofilin 1 promotes the pathogenicity and transmission of pathological α-synuclein in mouse models of Parkinson's disease.
Yan M, Xiong M, Dai L, Zhang X, Zha Y, Deng X, Yu Z, Zhang Z
NPJ Parkinson's disease 2022 Jan 10;8(1):1
NPJ Parkinson's disease 2022 Jan 10;8(1):1
Anti-tumor effect of Yanggan Huayu granule by inducing AKT-mediated apoptosis in hepatocellular carcinoma.
Shen Y, Yang F, Peng H, Zhang G, Zhu F, Xu H, Shi L
Journal of ethnopharmacology 2022 Jan 10;282:114601
Journal of ethnopharmacology 2022 Jan 10;282:114601
Xiaoyao powder improves endometrial receptivity via VEGFR-2-mediated angiogenesis through the activation of the JNK and P38 signaling pathways.
He M, Li L, Wei X, Geng D, Jiang H, Xiangxiang G, Zhang Y, Du H
Journal of ethnopharmacology 2022 Jan 10;282:114580
Journal of ethnopharmacology 2022 Jan 10;282:114580
Mechanical force promotes dimethylarginine dimethylaminohydrolase 1-mediated hydrolysis of the metabolite asymmetric dimethylarginine to enhance bone formation.
Xie Z, Hou L, Shen S, Wu Y, Wang J, Jie Z, Zhao X, Li X, Zhang X, Chen J, Xu W, Ning L, Ma Q, Wang S, Wang H, Yuan P, Fang X, Qin A, Fan S
Nature communications 2022 Jan 10;13(1):50
Nature communications 2022 Jan 10;13(1):50
RSL1D1 promotes the progression of colorectal cancer through RAN-mediated autophagy suppression.
Liu X, Chen J, Long X, Lan J, Liu X, Zhou M, Zhang S, Zhou J
Cell death & disease 2022 Jan 10;13(1):43
Cell death & disease 2022 Jan 10;13(1):43
Effects of Restricted Feeding on Growth Performance, Intestinal Immunity, and Skeletal Muscle Development in New Zealand Rabbits.
Zhuang J, Zhou T, Bai S, Zhao B, Wu X, Chen Y
Animals : an open access journal from MDPI 2022 Jan 10;12(2)
Animals : an open access journal from MDPI 2022 Jan 10;12(2)
RNA N(6)-methyladenosine modulates endothelial atherogenic responses to disturbed flow in mice.
Li B, Zhang T, Liu M, Cui Z, Zhang Y, Liu M, Liu Y, Sun Y, Li M, Tian Y, Yang Y, Jiang H, Liang D
eLife 2022 Jan 10;11
eLife 2022 Jan 10;11
Ajuba functions as a co-activator of C/EBPβ to induce expression of PPARγ and C/EBPα during adipogenesis.
Yan H, Li Q, Li M, Zou X, Bai N, Yu Z, Zhang J, Zhang D, Zhang Q, Wang J, Jia H, Wu Y, Hou Z
Molecular and cellular endocrinology 2022 Jan 1;539:111485
Molecular and cellular endocrinology 2022 Jan 1;539:111485
Highly sensitive detection of multiple proteins from single cells by MoS(2)-FET biosensors.
Wei J, Zhao Z, Lan K, Wang Z, Qin G, Chen R
Talanta 2022 Jan 1;236:122839
Talanta 2022 Jan 1;236:122839
Delayed inhibition of ERK and p38 attenuates neuropathic pain without affecting motor function recovery after peripheral nerve injury.
Huang S, Chen Y, Jia Y, Yang T, Su W, Zhu Z, Xue P, Feng F, Zhao Y, Chen G
Neuropharmacology 2022 Jan 1;202:108835
Neuropharmacology 2022 Jan 1;202:108835
NMN recruits GSH to enhance GPX4-mediated ferroptosis defense in UV irradiation induced skin injury.
Feng Z, Qin Y, Huo F, Jian Z, Li X, Geng J, Li Y, Wu J
Biochimica et biophysica acta. Molecular basis of disease 2022 Jan 1;1868(1):166287
Biochimica et biophysica acta. Molecular basis of disease 2022 Jan 1;1868(1):166287
Docosahexaenoic acid reduces hypoglycemia-induced neuronal necroptosis via the peroxisome proliferator-activated receptor γ/nuclear factor-κB pathway.
Huang L, Zhou Y, Gou ZX, Zhang F, Lu LQ
Brain research 2022 Jan 1;1774:147708
Brain research 2022 Jan 1;1774:147708
Epithelial Wntless regulates postnatal alveologenesis.
Fang Y, Shao H, Wu Q, Wong NC, Tsong N, Sime PJ, Que J
Development (Cambridge, England) 2022 Jan 1;149(1)
Development (Cambridge, England) 2022 Jan 1;149(1)
The Impact of Long-term Physical Inactivity on Adipose Tissue Immunometabolism.
Trim WV, Walhin JP, Koumanov F, Bouloumié A, Lindsay MA, Travers RL, Turner JE, Thompson D
The Journal of clinical endocrinology and metabolism 2022 Jan 1;107(1):177-191
The Journal of clinical endocrinology and metabolism 2022 Jan 1;107(1):177-191
Wuzhuyu Decoction relieves hyperalgesia by regulating central and peripheral 5-HT in chronic migraine model rats.
Nan N, Gong MX, Wang Q, Li MJ, Xu R, Ma Z, Wang SH, Zhao H, Xu YS
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Feb;96:153905
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Feb;96:153905
Normalizing hyperactivity of the Gunn rat with bilirubin-induced neurological disorders via ketanserin.
Miura S, Tsuchie K, Fukushima M, Arauchi R, Tsumori T, Otsuki K, Hayashida M, Hashioka S, Wake R, Miyaoka T, Inagaki M, Oh-Nishi A
Pediatric research 2022 Feb;91(3):556-564
Pediatric research 2022 Feb;91(3):556-564
Dapagliflozin alleviates advanced glycation end product induced podocyte injury through AMPK/mTOR mediated autophagy pathway.
Yang L, Liang B, Li J, Zhang X, Chen H, Sun J, Zhang Z
Cellular signalling 2022 Feb;90:110206
Cellular signalling 2022 Feb;90:110206
FOXL2 regulates the expression of the Col4a1 collagen gene in chicken granulosa cells.
Du H, Guo Y, Wu X, Gong Y
Molecular reproduction and development 2022 Feb;89(2):95-103
Molecular reproduction and development 2022 Feb;89(2):95-103
Transgelin-2 interacts with CD44 to regulate Notch1 signaling pathway and participates in colorectal cancer proliferation and migration.
Ding R, Li G, Yao Y, Zhang L, Zhang X, Li J, Shen T, Gao Y, Wu T, Kong S, Huang M, Li Y
Journal of physiology and biochemistry 2022 Feb;78(1):99-108
Journal of physiology and biochemistry 2022 Feb;78(1):99-108
DsbA-L interacts with VDAC1 in mitochondrion-mediated tubular cell apoptosis and contributes to the progression of acute kidney disease.
Li X, Pan J, Li H, Li G, Liu B, Tang X, Liu X, He Z, Peng Z, Zhang H, Wang L, Li Y, Xiang X, Chai X, Yuan Y, Zheng P, Zhang D
EBioMedicine 2022 Feb;76:103859
EBioMedicine 2022 Feb;76:103859
DHHC5 facilitates oligodendrocyte development by palmitoylating and activating STAT3.
Ma Y, Liu H, Ou Z, Qi C, Xing R, Wang S, Han Y, Zhao TJ, Chen Y
Glia 2022 Feb;70(2):379-392
Glia 2022 Feb;70(2):379-392
AKT1/HK2 Axis-mediated Glucose Metabolism: A Novel Therapeutic Target of Sulforaphane in Bladder Cancer.
Huang L, He C, Zheng S, Wu C, Ren M, Shan Y
Molecular nutrition & food research 2022 Feb;66(3):e2100738
Molecular nutrition & food research 2022 Feb;66(3):e2100738
Divergent immunometabolic changes in adipose tissue and skeletal muscle with ageing in healthy humans.
Trim WV, Walhin JP, Koumanov F, Bouloumié A, Lindsay MA, Chen YC, Travers RL, Turner JE, Thompson D
The Journal of physiology 2022 Feb;600(4):921-947
The Journal of physiology 2022 Feb;600(4):921-947
Pan-cancer multi-omics analyses reveal crosstalk between the Hippo and immune signaling pathways in the tumor microenvironment.
Wang C, Zhu T, Zhao Z, Chen B, Chen T, Dong Q, Liu M, Zhuang S, Yang F, Liu Y, Yang M, Gu Y, Liang H
FEBS letters 2022 Feb;596(4):449-464
FEBS letters 2022 Feb;596(4):449-464
MiR-597-5p suppresses the progression of hepatocellular carcinoma via targeting transcriptional enhancer associate domain transcription factor 1 (TEAD1).
Sun X, Hou Z, Li N, Zhang S
In vitro cellular & developmental biology. Animal 2022 Feb;58(2):96-108
In vitro cellular & developmental biology. Animal 2022 Feb;58(2):96-108
Follicle-stimulating hormone regulates glycolysis of water buffalo follicular granulosa cells through AMPK/SIRT1 signalling pathway.
Pan Y, Zhu J, Lv Q, Shi D, Yang S, Xing Q, Zhang R, Cheng J, Deng Y
Reproduction in domestic animals = Zuchthygiene 2022 Feb;57(2):185-195
Reproduction in domestic animals = Zuchthygiene 2022 Feb;57(2):185-195
Inhibition of gap junction communication between cells can induce apoptosis of corpus cavernosum smooth muscle in guinea pigs.
Wang Y, Wang J, Hao Z, Yang H, Li Y, Tan M, Liu L, Feng S, Mei L, Qian B
Andrologia 2022 Feb;54(1):e14287
Andrologia 2022 Feb;54(1):e14287
Crosstalk Between RPE Cells and Choroidal Endothelial Cells via the ANXA1/FPR2/SHP2/NLRP3 Inflammasome/Pyroptosis Axis Promotes Choroidal Neovascularization.
Zhu M, Wang Y, Zhu L, Du S, Wang Z, Zhang Y, Guo Y, Tu Y, Song E
Inflammation 2022 Feb;45(1):414-427
Inflammation 2022 Feb;45(1):414-427
Supervillin Contributes to LPS-induced Inflammatory Response in THP-1 Cell-derived Macrophages.
Zhou J, Que Y, Pan L, Li X, Zhu C, Jin L, Li S
Inflammation 2022 Feb;45(1):356-371
Inflammation 2022 Feb;45(1):356-371
PDCD4 Simultaneously Promotes Microglia Activation via PDCD4-MAPK-NF-κB Positive Loop and Facilitates Neuron Apoptosis During Neuroinflammation.
Chen Q, Lu H, Duan C, Zhu X, Zhang Y, Li M, Zhang D
Inflammation 2022 Feb;45(1):234-252
Inflammation 2022 Feb;45(1):234-252
Tenascin-C Participates Pulmonary Injury Induced by Paraquat Through Regulating TLR4 and TGF-β Signaling Pathways.
Zhang D, Liu Z, Liu Q, Lan H, Peng J, Liu X, Liu W
Inflammation 2022 Feb;45(1):222-233
Inflammation 2022 Feb;45(1):222-233
CACNA1B facilitates breast cancer cell growth and migration by regulating cyclin D1 and EMT: the implication of CACNA1B in breast cancer.
Jin YM, Ye Y, Bao WQ, Tong Y, Ni SB, Liu JP, Zhao B
Journal of receptor and signal transduction research 2022 Feb;42(1):1-8
Journal of receptor and signal transduction research 2022 Feb;42(1):1-8
The m(6)A reading protein YTHDF3 potentiates tumorigenicity of cancer stem-like cells in ocular melanoma through facilitating CTNNB1 translation.
Xu Y, He X, Wang S, Sun B, Jia R, Chai P, Li F, Yang Y, Ge S, Jia R, Yang YG, Fan X
Oncogene 2022 Feb;41(9):1281-1297
Oncogene 2022 Feb;41(9):1281-1297
Tanshinone IIA inhibits gastric cancer cell stemness through inducing ferroptosis.
Ni H, Ruan G, Sun C, Yang X, Miao Z, Li J, Chen Y, Qin H, Liu Y, Zheng L, Xing Y, Xi T, Li X
Environmental toxicology 2022 Feb;37(2):192-200
Environmental toxicology 2022 Feb;37(2):192-200
Estrogen receptor beta increases clear cell renal cell carcinoma stem cell phenotype via altering the circPHACTR4/miR-34b-5p/c-Myc signaling.
Wang Y, Yang Z, Gu J, Zhang Y, Wang X, Teng Z, Wang D, Gao L, Li W, Yeh S, Han Z
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2022 Feb;36(2):e22163
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2022 Feb;36(2):e22163
Spindle pole body component 24 homolog potentiates tumor progression via regulation of SRY-box transcription factor 2 in clear cell renal cell carcinoma.
Sun C, Wei J, Long Z, Zhao W, Huangfu Q, Xie Q, Wang B, Wen J
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2022 Feb;36(2):e22086
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2022 Feb;36(2):e22086
The STING-IRF3 pathway contributes to paraquat-induced acute lung injury.
Wang N, Wang X, Li Y, Shen H, Liu Z, Ma Z, Li Q, Zhao M
Toxicology mechanisms and methods 2022 Feb;32(2):145-157
Toxicology mechanisms and methods 2022 Feb;32(2):145-157
Neuroglobin expression and function in the temporal cortex of bilirubin encephalopathy rats.
Hu JH, Fan P, Zhang LR, Chen CY, Xu J, Huang J, Lu WT, Zhu SJ, Qiu GP, Xu SY, Ran JH, Gan SW
Anatomical record (Hoboken, N.J. : 2007) 2022 Feb;305(2):254-264
Anatomical record (Hoboken, N.J. : 2007) 2022 Feb;305(2):254-264
Phosphorylated PAMAM dendrimers: an analog of dentin non-collagenous proteins, enhancing the osteo/odontogenic differentiation of dental pulp stem cells.
Liu J, Gao Y, Zhu X, Zhang Y, Xu H, Wang T, Zhang G
Clinical oral investigations 2022 Feb;26(2):1737-1751
Clinical oral investigations 2022 Feb;26(2):1737-1751
Altered transsulfuration pathway enzymes and redox homeostasis in inherited retinal degenerative diseases.
Badiei A, Beltran WA, Aguirre GD
Experimental eye research 2022 Feb;215:108902
Experimental eye research 2022 Feb;215:108902
Retinal degeneration in humanized mice expressing mutant rhodopsin under the control of the endogenous murine promoter.
Liu X, Jia R, Meng X, Li Y, Yang L
Experimental eye research 2022 Feb;215:108893
Experimental eye research 2022 Feb;215:108893
NCAPH promotes cell proliferation and inhibits cell apoptosis of bladder cancer cells through MEK/ERK signaling pathway.
Li B, Xiao Q, Shan L, Song Y
Cell cycle (Georgetown, Tex.) 2022 Feb;21(4):427-438
Cell cycle (Georgetown, Tex.) 2022 Feb;21(4):427-438
Demethylenetetrahydroberberine protects dopaminergic neurons in a mouse model of Parkinson's disease.
Wen J, Zhang YQ, Liu DQ, Yao XT, Jiang H, Zhang YB
Chinese journal of natural medicines 2022 Feb;20(2):111-119
Chinese journal of natural medicines 2022 Feb;20(2):111-119
Assessing Mitochondrial DNA Release into the Cytosol and Subsequent Activation of Innate Immune-related Pathways in Mammalian Cells.
Bryant JD, Lei Y, VanPortfliet JJ, Winters AD, West AP
Current protocols 2022 Feb;2(2):e372
Current protocols 2022 Feb;2(2):e372
Combination of the 6-thioguanine and disulfiram/Cu synergistically inhibits proliferation of triple-negative breast cancer cells by enhancing DNA damage and disrupting DNA damage checkpoint.
Chu M, An X, Zhang D, Li Q, Dai X, Yu H, Li Z
Biochimica et biophysica acta. Molecular cell research 2022 Feb;1869(2):119169
Biochimica et biophysica acta. Molecular cell research 2022 Feb;1869(2):119169
Dietary mulberry-leaf flavonoids improve the eggshell quality of aged breeder hens.
Huang Z, Dai H, Jiang J, Ye N, Zhu S, Wei Q, Lv Z, Shi F
Theriogenology 2022 Feb;179:177-186
Theriogenology 2022 Feb;179:177-186
Pre-clinical study of human umbilical cord mesenchymal stem cell transplantation for the treatment of traumatic brain injury: safety evaluation from immunogenic and oncogenic perspectives.
Wang G, Wu HL, Liu YP, Yan DQ, Yuan ZL, Chen L, Yang Q, Gao YS, Diao B
Neural regeneration research 2022 Feb;17(2):354-361
Neural regeneration research 2022 Feb;17(2):354-361
Upregulated hexokinase 2 expression induces the apoptosis of dopaminergic neurons by promoting lactate production in Parkinson's disease.
Li J, Chen L, Qin Q, Wang D, Zhao J, Gao H, Yuan X, Zhang J, Zou Y, Mao Z, Xiong Y, Min Z, Yan M, Wang CY, Xue Z
Neurobiology of disease 2022 Feb;163:105605
Neurobiology of disease 2022 Feb;163:105605
Withaferin A alleviates ethanol-induced liver injury by inhibiting hepatic lipogenesis.
Hamada K, Wang P, Xia Y, Yan N, Takahashi S, Krausz KW, Hao H, Yan T, Gonzalez FJ
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2022 Feb;160:112807
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2022 Feb;160:112807
FGF19 protects against obesity-induced bone loss by promoting osteogenic differentiation.
Guo A, Li K, Tian HC, Tao BL, Xiao Q, Jiang DM
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Feb;146:112524
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Feb;146:112524
Ubiquitin-specific peptidase 2 inhibits epithelial-mesenchymal transition in clear cell renal cell carcinoma metastasis by downregulating the NF-κB pathway.
Duan J, Jin M, Yang D, Shi J, Gao J, Guo D, Tang H, Zhang S, Qiao B
Bioengineered 2022 Feb;13(2):4455-4467
Bioengineered 2022 Feb;13(2):4455-4467
Long non-coding RNA TRPM2 antisense RNA as a potential therapeutic target promotes tumorigenesis and metastasis in esophageal cancer.
Wang W, Dai Y, Yang X, Xiong X
Bioengineered 2022 Feb;13(2):4397-4410
Bioengineered 2022 Feb;13(2):4397-4410
Timosaponin B-II alleviates osteoarthritis-related inflammation and extracellular matrix degradation through inhibition of mitogen-activated protein kinases and nuclear factor-κB pathways in vitro.
Liu X, Xiang D, Jin W, Zhao G, Li H, Xie B, Gu X
Bioengineered 2022 Feb;13(2):3450-3461
Bioengineered 2022 Feb;13(2):3450-3461
Calcium-activated nucleotides 1 (CANT1)-driven nuclear factor-k-gene binding (NF-ĸB) signaling pathway facilitates the lung cancer progression.
Gao F, Hu X, Liu W, Wu H, Mu Y, Zhao Y
Bioengineered 2022 Feb;13(2):3183-3193
Bioengineered 2022 Feb;13(2):3183-3193
3-hydroxy butyrate dehydrogenase 2 deficiency aggravates systemic lupus erythematosus progression in a mouse model by promoting CD40 ligand demethylation.
Yang B, Hou S, Zhao J, Li Y
Bioengineered 2022 Feb;13(2):2685-2695
Bioengineered 2022 Feb;13(2):2685-2695
Knockdown of ADORA2A antisense RNA 1 inhibits cell proliferation and enhances imatinib sensitivity in chronic myeloid leukemia.
Liu Y, Li H, Zhao Y, Li D, Zhang Q, Fu J, Fan S
Bioengineered 2022 Feb;13(2):2296-2307
Bioengineered 2022 Feb;13(2):2296-2307
circRNAome profiling reveals circFgfr2 regulates myogenesis and muscle regeneration via a feedback loop.
Yan J, Yang Y, Fan X, Liang G, Wang Z, Li J, Wang L, Chen Y, Adetula AA, Tang Y, Li K, Wang D, Tang Z
Journal of cachexia, sarcopenia and muscle 2022 Feb;13(1):696-712
Journal of cachexia, sarcopenia and muscle 2022 Feb;13(1):696-712
Histone deacetylase inhibitors inhibit cervical cancer growth through Parkin acetylation-mediated mitophagy.
Sun X, Shu Y, Ye G, Wu C, Xu M, Gao R, Huang D, Zhang J
Acta pharmaceutica Sinica. B 2022 Feb;12(2):838-852
Acta pharmaceutica Sinica. B 2022 Feb;12(2):838-852
Anti-aging effects of chlorpropamide depend on mitochondrial complex-II and the production of mitochondrial reactive oxygen species.
Mao Z, Liu W, Huang Y, Sun T, Bao K, Feng J, Moskalev A, Hu Z, Li J
Acta pharmaceutica Sinica. B 2022 Feb;12(2):665-677
Acta pharmaceutica Sinica. B 2022 Feb;12(2):665-677
Celastrol attenuates the remodeling of pulmonary vascular and right ventricular in monocrotaline-induced pulmonary arterial hypertension in rats.
Li H, Liu Q, Yue Y, Wang S, Huang S, Huang L, Luo L, Zhang Y, Wu Z
Cardiovascular diagnosis and therapy 2022 Feb;12(1):88-102
Cardiovascular diagnosis and therapy 2022 Feb;12(1):88-102
Maternal exposure to PM2.5 induces the testicular cell apoptosis in offspring triggered by the UPR-mediated JNK pathway.
Ren L, Jiang J, Huang J, Zang Y, Huang Q, Zhang L, Wei J, Lu H, Wu S, Zhou X
Toxicology research 2022 Feb;11(1):226-234
Toxicology research 2022 Feb;11(1):226-234
Downregulation of acylglycerol kinase suppresses high-glucose-induced endothelial-mesenchymal transition in human retinal microvascular endothelial cells through regulating the LPAR1/TGF-β/Notch signaling pathway.
Wang H, Feng Z, Han X, Xing Y, Zhang X
Canadian journal of physiology and pharmacology 2022 Feb;100(2):142-150
Canadian journal of physiology and pharmacology 2022 Feb;100(2):142-150
Identification of key biomarkers and immune infiltration in renal interstitial fibrosis.
Hu Z, Liu Y, Zhu Y, Cui H, Pan J
Annals of translational medicine 2022 Feb;10(4):190
Annals of translational medicine 2022 Feb;10(4):190
Cold-inducible RNA-binding protein regulates cyclin B1 against spermatogenesis arrest caused by heat stress.
Liu H, Xu C, Bao M, Huang J, Zou L, Fan X, Zhu C, Xia W
Andrology 2022 Feb;10(2):392-403
Andrology 2022 Feb;10(2):392-403
Phenotypic and genotypic changes in obesity and type 2 diabetes of male KK mice with aging.
Iizuka Y, Kim H, Nakasatomi M, Matsumoto A, Shimizu J
Experimental animals 2022 Feb 9;71(1):71-81
Experimental animals 2022 Feb 9;71(1):71-81
Mechanisms and Molecular Targets of BuShenHuoXue Formula for Osteoarthritis.
Xiong W, Zhao J, Ma X, Feng Z
ACS omega 2022 Feb 8;7(5):4703-4713
ACS omega 2022 Feb 8;7(5):4703-4713
Rpsa Signaling Regulates Cortical Neuronal Morphogenesis via Its Ligand, PEDF, and Plasma Membrane Interaction Partner, Itga6.
Blazejewski SM, Bennison SA, Ha NT, Liu X, Smith TH, Dougherty KJ, Toyo-Oka K
Cerebral cortex (New York, N.Y. : 1991) 2022 Feb 8;32(4):770-795
Cerebral cortex (New York, N.Y. : 1991) 2022 Feb 8;32(4):770-795
Neuroprotective effects of alisol A 24-acetate on cerebral ischaemia-reperfusion injury are mediated by regulating the PI3K/AKT pathway.
Lu T, Li H, Zhou Y, Wei W, Ding L, Zhan Z, Liu W, Tao J, Xue X
Journal of neuroinflammation 2022 Feb 7;19(1):37
Journal of neuroinflammation 2022 Feb 7;19(1):37
Pigment epithelium-derived factor may induce antidepressant phenotypes in mice by the prefrontal cortex.
Bai M, Yu H, Chen C, Xu X, He Y, Wang Y, Tian Y, Wu Z, Lan T, Li Y, Chen X, Chen Z, Zhao L, Fang L, Yang D, Cheng K, Xie P
Neuroscience letters 2022 Feb 6;771:136423
Neuroscience letters 2022 Feb 6;771:136423
Hepatocyte nuclear factor 4 gamma (HNF4G) is correlated with poor prognosis and promotes tumor cell growth by inhibiting caspase-dependent intrinsic apoptosis in colorectal cancer.
Chen L, Shi H, Wang X, Wang T, Wang Y, Wu Z, Zhang W, Chen H, Zhong M, Mao X, Shi X, Li Q
European journal of pharmacology 2022 Feb 5;916:174727
European journal of pharmacology 2022 Feb 5;916:174727
Aloe-emodin derivative produces anti-atherosclerosis effect by reinforcing AMBRA1-mediated endothelial autophagy.
Tang X, Zhang Y, Liu X, Li X, Zhao H, Cui H, Shi Y, Chen Y, Xu H, Meng Z, Zhao L, Chen H, Wang Z, Zhu M, Lin Y, Yang B, Zhang Y
European journal of pharmacology 2022 Feb 5;916:174641
European journal of pharmacology 2022 Feb 5;916:174641
Design and synthesis of marine sesterterpene analogues as novel estrogen receptor α degraders for breast cancer treatment.
Liang JJ, Yu WL, Yang L, Xie BH, Qin KM, Yin YP, Yan JJ, Gong S, Liu TY, Zhou HB, Hong K
European journal of medicinal chemistry 2022 Feb 5;229:114081
European journal of medicinal chemistry 2022 Feb 5;229:114081
Toddalolactone protects against osteoarthritis by ameliorating chondrocyte inflammation and suppressing osteoclastogenesis.
Xu Y, Xue S, Zhang T, Jin X, Wang C, Lu H, Zhong Y, Chen H, Zhu L, Ma J, Sang W
Chinese medicine 2022 Feb 5;17(1):18
Chinese medicine 2022 Feb 5;17(1):18
Intracellular CYTL1, a novel tumor suppressor, stabilizes NDUFV1 to inhibit metabolic reprogramming in breast cancer.
Xue W, Li X, Li W, Wang Y, Jiang C, Zhou L, Gao J, Yu Y, Shen Y, Xu Q
Signal transduction and targeted therapy 2022 Feb 4;7(1):35
Signal transduction and targeted therapy 2022 Feb 4;7(1):35
Proteomic Identification of the SLC25A46 Interactome in Transgenic Mice Expressing SLC25A46-FLAG.
Perivolidi VI, Violitzi F, Ioannidou E, Rinotas V, Stamatakis G, Samiotaki M, Panayotou G, Douni E
Journal of proteome research 2022 Feb 4;21(2):375-394
Journal of proteome research 2022 Feb 4;21(2):375-394
Differential regulation of progranulin derived granulin peptides.
Zhang T, Du H, Santos MN, Wu X, Pagan MD, Trigiani LJ, Nishimura N, Reinheckel T, Hu F
Molecular neurodegeneration 2022 Feb 4;17(1):15
Molecular neurodegeneration 2022 Feb 4;17(1):15
Amino acid starvation-induced LDLR trafficking accelerates lipoprotein endocytosis and LDL clearance.
Chen Y, Wu X, Zhang J, Pan G, Wang X, Guo X, Wang J, Cui X, Gao H, Cheng M, Yang J, Zhang C, Jiang F
EMBO reports 2022 Feb 3;23(3):e53373
EMBO reports 2022 Feb 3;23(3):e53373
Licochalcone B specifically inhibits the NLRP3 inflammasome by disrupting NEK7-NLRP3 interaction.
Li Q, Feng H, Wang H, Wang Y, Mou W, Xu G, Zhang P, Li R, Shi W, Wang Z, Fang Z, Ren L, Wang Y, Lin L, Hou X, Dai W, Li Z, Wei Z, Liu T, Wang J, Guo Y, Li P, Zhao X, Zhan X, Xiao X, Bai Z
EMBO reports 2022 Feb 3;23(2):e53499
EMBO reports 2022 Feb 3;23(2):e53499
Commonality and diversity in tRNA substrate recognition in t6A biogenesis by eukaryotic KEOPSs.
Wang JT, Zhou JB, Mao XL, Zhou L, Chen M, Zhang W, Wang ED, Zhou XL
Nucleic acids research 2022 Feb 28;50(4):2223-2239
Nucleic acids research 2022 Feb 28;50(4):2223-2239
NVP-AUY922 alleviates radiation-induced lung injury via inhibition of autophagy-dependent ferroptosis.
Li L, Wu D, Deng S, Li J, Zhang F, Zou Y, Zhang T, Xu Y
Cell death discovery 2022 Feb 26;8(1):86
Cell death discovery 2022 Feb 26;8(1):86
Characterization of lncRNA functioning in ovine conceptuses and endometria during the peri-implantation period.
Matsuno Y, Kusama K, Imakawa K
Biochemical and biophysical research communications 2022 Feb 26;594:22-30
Biochemical and biophysical research communications 2022 Feb 26;594:22-30
CircCYP24A1 hampered malignant phenotype of renal cancer carcinoma through modulating CMTM-4 expression via sponging miR-421.
Wu X, Zhou J, Zhao L, Yang Z, Yang C, Chen Y, Xue W
Cell death & disease 2022 Feb 26;13(2):190
Cell death & disease 2022 Feb 26;13(2):190
Widespread Mislocalization of FUS Is Associated With Mitochondrial Abnormalities in Skeletal Muscle in Amyotrophic Lateral Sclerosis With FUS Mutations.
Yu M, Zhao X, Wu W, Wang Q, Liu J, Zhang W, Yuan Y, Hong D, Wang Z, Deng J
Journal of neuropathology and experimental neurology 2022 Feb 24;81(3):172-181
Journal of neuropathology and experimental neurology 2022 Feb 24;81(3):172-181
Comprehensive Analysis of Protein Acetylation and Glucose Metabolism in Mouse Brains Infected with Rabies Virus.
Pei J, Yuan Y, Tian D, Huang F, Zhang C, Wang C, Zhou M, Chen H, Fu Z, Zhao L
Journal of virology 2022 Feb 23;96(4):e0194221
Journal of virology 2022 Feb 23;96(4):e0194221
Targeting polarized phenotype of microglia via IL6/JAK2/STAT3 signaling to reduce NSCLC brain metastasis.
Jin Y, Kang Y, Wang M, Wu B, Su B, Yin H, Tang Y, Li Q, Wei W, Mei Q, Hu G, Lukacs-Kornek V, Li J, Wu K, Yuan X, Wang W
Signal transduction and targeted therapy 2022 Feb 23;7(1):52
Signal transduction and targeted therapy 2022 Feb 23;7(1):52
PD-L1 mediates lung fibroblast to myofibroblast transition through Smad3 and β-catenin signaling pathways.
Guo X, Sunil C, Adeyanju O, Parker A, Huang S, Ikebe M, Tucker TA, Idell S, Qian G
Scientific reports 2022 Feb 23;12(1):3053
Scientific reports 2022 Feb 23;12(1):3053
Avian Hepatitis E Virus ORF2 Protein Interacts with Rap1b to Induce Cytoskeleton Rearrangement That Facilitates Virus Internalization.
Zhang B, Fan M, Fan J, Luo Y, Wang J, Wang Y, Liu B, Sun Y, Zhao Q, Hiscox JA, Nan Y, Zhou EM
Microbiology spectrum 2022 Feb 23;10(1):e0226521
Microbiology spectrum 2022 Feb 23;10(1):e0226521
Listeria toxin promotes phosphorylation of the inflammasome adaptor ASC through Lyn and Syk to exacerbate pathogen expansion.
Tanishita Y, Sekiya H, Inohara N, Tsuchiya K, Mitsuyama M, Núñez G, Hara H
Cell reports 2022 Feb 22;38(8):110414
Cell reports 2022 Feb 22;38(8):110414
D-mannose facilitates immunotherapy and radiotherapy of triple-negative breast cancer via degradation of PD-L1.
Zhang R, Yang Y, Dong W, Lin M, He J, Zhang X, Tian T, Yang Y, Chen K, Lei QY, Zhang S, Xu Y, Lv L
Proceedings of the National Academy of Sciences of the United States of America 2022 Feb 22;119(8)
Proceedings of the National Academy of Sciences of the United States of America 2022 Feb 22;119(8)
S-20, a steroidal saponin from the berries of black nightshade, exerts anti-multidrug resistance activity in K562/ADR cells through autophagic cell death and ERK activation.
Wang Y, Xu J, Wang Y, Xiang L, He X
Food & function 2022 Feb 21;13(4):2200-2215
Food & function 2022 Feb 21;13(4):2200-2215
Cadmium and molybdenum co-induce pyroptosis and apoptosis via the PTEN/PI3K/AKT axis in the livers of Shaoxing ducks (Anas platyrhynchos).
Cao P, Nie G, Luo J, Hu R, Li G, Hu G, Zhang C
Food & function 2022 Feb 21;13(4):2142-2154
Food & function 2022 Feb 21;13(4):2142-2154
CircNEIL3 mediates pyroptosis to influence lung adenocarcinoma radiotherapy by upregulating PIF1 through miR-1184 inhibition.
Zhang T, Wu DM, Luo PW, Liu T, Han R, Deng SH, He M, Zhao YY, Xu Y
Cell death & disease 2022 Feb 21;13(2):167
Cell death & disease 2022 Feb 21;13(2):167
WT1 suppresses follicle-stimulating hormone-induced progesterone secretion by regulating ERK1/2 pathway in chicken preovulatory granulosa cells.
Tang S, Li X, Wu X, Gong Y
Gene 2022 Feb 20;812:146097
Gene 2022 Feb 20;812:146097
OTUB2 regulates KRT80 stability via deubiquitination and promotes tumour proliferation in gastric cancer.
Ouyang S, Zeng Z, Liu Z, Zhang Z, Sun J, Wang X, Ma M, Ye X, Yu J, Kang W
Cell death discovery 2022 Feb 2;8(1):45
Cell death discovery 2022 Feb 2;8(1):45
Autophagic Schwann cells promote perineural invasion mediated by the NGF/ATG7 paracrine pathway in pancreatic cancer.
Zhang W, He R, Yang W, Zhang Y, Yuan Q, Wang J, Liu Y, Chen S, Zhang S, Zhang W, Zhu Z, Zhang J, Wang Z, Li J
Journal of experimental & clinical cancer research : CR 2022 Feb 2;41(1):48
Journal of experimental & clinical cancer research : CR 2022 Feb 2;41(1):48
Maresin 1 promotes nerve regeneration and alleviates neuropathic pain after nerve injury.
Wei J, Su W, Zhao Y, Wei Z, Hua Y, Xue P, Zhu X, Chen Y, Chen G
Journal of neuroinflammation 2022 Feb 2;19(1):32
Journal of neuroinflammation 2022 Feb 2;19(1):32
LncRNA FIRRE functions as a tumor promoter by interaction with PTBP1 to stabilize BECN1 mRNA and facilitate autophagy.
Wang Y, Li Z, Xu S, Li W, Chen M, Jiang M, Fan X
Cell death & disease 2022 Feb 2;13(2):98
Cell death & disease 2022 Feb 2;13(2):98
Mesenchyme homeobox 2 has a cancer-inhibiting function in breast carcinoma via affection of the PI3K/AKT/mTOR and ERK1/2 pathways.
Cai Y, Liu Y, Sun Y, Ren Y
Biochemical and biophysical research communications 2022 Feb 19;593:20-27
Biochemical and biophysical research communications 2022 Feb 19;593:20-27
The deubiquitinating enzyme USP20 regulates the stability of the MCL1 protein.
Feng J, Liu P, Li X, Zhang D, Lin H, Hou Z, Guo C, Niu Y, Dai B, Wang O, Qi M, Wang H, Zhou H
Biochemical and biophysical research communications 2022 Feb 19;593:122-128
Biochemical and biophysical research communications 2022 Feb 19;593:122-128
CRISPR screening of E3 ubiquitin ligases reveals Ring Finger Protein 185 as a novel tumor suppressor in glioblastoma repressed by promoter hypermethylation and miR-587.
Lin K, Shen SH, Lu F, Zheng P, Wu S, Liao J, Jiang X, Zeng G, Wei D
Journal of translational medicine 2022 Feb 19;20(1):96
Journal of translational medicine 2022 Feb 19;20(1):96
METTL3 promotes oxaliplatin resistance of gastric cancer CD133+ stem cells by promoting PARP1 mRNA stability.
Li H, Wang C, Lan L, Yan L, Li W, Evans I, Ruiz EJ, Su Q, Zhao G, Wu W, Zhang H, Zhou Z, Hu Z, Chen W, Oliveira JM, Behrens A, Reis RL, Zhang C
Cellular and molecular life sciences : CMLS 2022 Feb 18;79(3):135
Cellular and molecular life sciences : CMLS 2022 Feb 18;79(3):135
Elevated expression of the rhythm gene NFIL3 promotes the progression of TNBC by activating NF-κB signaling through suppression of NFKBIA transcription.
Yang W, Li J, Zhang M, Yu H, Zhuang Y, Zhao L, Ren L, Gong J, Bi H, Zeng L, Xue Y, Yang J, Zhao Y, Wang S, Gao S, Fu Z, Li D, Zhang J, Wang T, Shan M, Tang B, Li X
Journal of experimental & clinical cancer research : CR 2022 Feb 18;41(1):67
Journal of experimental & clinical cancer research : CR 2022 Feb 18;41(1):67
Nrf2 activation reprograms macrophage intermediary metabolism and suppresses the type I interferon response.
Ryan DG, Knatko EV, Casey AM, Hukelmann JL, Dayalan Naidu S, Brenes AJ, Ekkunagul T, Baker C, Higgins M, Tronci L, Nikitopolou E, Honda T, Hartley RC, O'Neill LAJ, Frezza C, Lamond AI, Abramov AY, Arthur JSC, Cantrell DA, Murphy MP, Dinkova-Kostova AT
iScience 2022 Feb 18;25(2):103827
iScience 2022 Feb 18;25(2):103827
PINK1-parkin-mediated neuronal mitophagy deficiency in prion disease.
Li J, Lai M, Zhang X, Li Z, Yang D, Zhao M, Wang D, Sun Z, Ehsan S, Li W, Gao H, Zhao D, Yang L
Cell death & disease 2022 Feb 18;13(2):162
Cell death & disease 2022 Feb 18;13(2):162
E3 ligase RNF167 and deubiquitinase STAMBPL1 modulate mTOR and cancer progression.
Wang D, Xu C, Yang W, Chen J, Ou Y, Guan Y, Guan J, Liu Y
Molecular cell 2022 Feb 17;82(4):770-784.e9
Molecular cell 2022 Feb 17;82(4):770-784.e9
Chronic exposure to polystyrene microplastics induced male reproductive toxicity and decreased testosterone levels via the LH-mediated LHR/cAMP/PKA/StAR pathway.
Jin H, Yan M, Pan C, Liu Z, Sha X, Jiang C, Li L, Pan M, Li D, Han X, Ding J
Particle and fibre toxicology 2022 Feb 17;19(1):13
Particle and fibre toxicology 2022 Feb 17;19(1):13
Circ-AFAP1 promote clear cell renal cell carcinoma growth and angiogenesis by the Circ-AFAP1/miR-374b-3p/VEGFA signaling axis.
Ou Y, Dai X, Chen X, Chen Y, Wu S, Zhou Q, Yang C, Jiang H
Cell death discovery 2022 Feb 16;8(1):68
Cell death discovery 2022 Feb 16;8(1):68
Preparation, Characterization, Evaluation of Neuroprotective Effect, and Related Mechanisms of Phosphatidylserine Emulsion in 5- and 12-Week Old Mice.
Liu B, Zhang N, Yang J, Sun W, Zhang R, Zheng X, Wang Z, Siebert HC, Han J
Journal of agricultural and food chemistry 2022 Feb 16;70(6):1852-1864
Journal of agricultural and food chemistry 2022 Feb 16;70(6):1852-1864
Protein C receptor maintains cancer stem cell properties via activating lipid synthesis in nasopharyngeal carcinoma.
Zhang P, He Q, Wang Y, Zhou G, Chen Y, Tang L, Zhang Y, Hong X, Mao Y, He Q, Yang X, Liu N, Ma J
Signal transduction and targeted therapy 2022 Feb 16;7(1):46
Signal transduction and targeted therapy 2022 Feb 16;7(1):46
Disuse-associated loss of the protease LONP1 in muscle impairs mitochondrial function and causes reduced skeletal muscle mass and strength.
Xu Z, Fu T, Guo Q, Zhou D, Sun W, Zhou Z, Chen X, Zhang J, Liu L, Xiao L, Yin Y, Jia Y, Pang E, Chen Y, Pan X, Fang L, Zhu MS, Fei W, Lu B, Gan Z
Nature communications 2022 Feb 16;13(1):894
Nature communications 2022 Feb 16;13(1):894
γ-mangostin attenuates amyloid-β42-induced neuroinflammation and oxidative stress in microglia-like BV2 cells via the mitogen-activated protein kinases signaling pathway.
Kong C, Jia L, Jia J
European journal of pharmacology 2022 Feb 15;917:174744
European journal of pharmacology 2022 Feb 15;917:174744
Synthesis of lathyrane diterpenoid nitrogen-containing heterocyclic derivatives and evaluation of their anti-inflammatory activities.
Wang W, Xiong L, Li Y, Song Z, Sun D, Li H, Chen L
Bioorganic & medicinal chemistry 2022 Feb 15;56:116627
Bioorganic & medicinal chemistry 2022 Feb 15;56:116627
Synthesis and biological evaluation of aminobenzamides containing purine moiety as class I histone deacetylases inhibitors.
Mao PT, He WB, Mai X, Feng LH, Li N, Liao YJ, Zhu CS, Li J, Chen T, Liu SH, Zhang QM, He L
Bioorganic & medicinal chemistry 2022 Feb 15;56:116599
Bioorganic & medicinal chemistry 2022 Feb 15;56:116599
Liquiritigenin alleviates doxorubicin-induced chronic heart failure via promoting ARHGAP18 and suppressing RhoA/ROCK1 pathway.
Xu Z, Hu Z, Xu H, Zhang L, Li L, Wang Y, Zhu Y, Yang L, Hu D
Experimental cell research 2022 Feb 15;411(2):113008
Experimental cell research 2022 Feb 15;411(2):113008
Substrate rigidity dictates colorectal tumorigenic cell stemness and metastasis via CRAD-dependent mechanotransduction.
Chang Y, Zhang J, Huo X, Qu X, Xia C, Huang K, Xie F, Wang N, Wei X, Jia Q
Cell reports 2022 Feb 15;38(7):110390
Cell reports 2022 Feb 15;38(7):110390
TBK1-METTL3 axis facilitates antiviral immunity.
Chen J, Wei X, Wang X, Liu T, Zhao Y, Chen L, Luo Y, Du H, Li Y, Liu T, Cao L, Zhou Z, Zhang Z, Liang L, Li L, Yan X, Zhang X, Deng X, Yang G, Yin P, Hao J, Yin Z, You F
Cell reports 2022 Feb 15;38(7):110373
Cell reports 2022 Feb 15;38(7):110373
Defective STAT5 Activation and Aberrant Expression of BCL6 in Naive CD4 T Cells Enhances Follicular Th Cell-like Differentiation in Patients with Granulomatosis with Polyangiitis.
Kim S, Boehme L, Nel L, Casian A, Sangle S, Nova-Lamperti E, Seitan V, Spencer J, Lavender P, D'Cruz DP, John S
Journal of immunology (Baltimore, Md. : 1950) 2022 Feb 15;208(4):807-818
Journal of immunology (Baltimore, Md. : 1950) 2022 Feb 15;208(4):807-818
Cotranslational interaction of human EBP50 and ezrin overcomes masked binding site during complex assembly.
Khan K, Long B, Baleanu-Gogonea C, Gogonea V, Deshpande GM, Vasu K, Fox PL
Proceedings of the National Academy of Sciences of the United States of America 2022 Feb 15;119(7)
Proceedings of the National Academy of Sciences of the United States of America 2022 Feb 15;119(7)
Cartilage Repair Using Clematis Triterpenoid Saponin Delivery Microcarrier, Cultured in a Microgravity Bioreactor Prior to Application in Rabbit Model.
Tu P, Pan Y, Wu C, Yang G, Zhou X, Sun J, Wang L, Liu M, Wang Z, Liang Z, Guo Y, Ma Y
ACS biomaterials science & engineering 2022 Feb 14;8(2):753-764
ACS biomaterials science & engineering 2022 Feb 14;8(2):753-764
Multienzymatic Antioxidant Activity of Manganese-Based Nanoparticles for Protection against Oxidative Cell Damage.
Zhang Y, Chen L, Sun R, Lv R, Du T, Li Y, Zhang X, Sheng R, Qi Y
ACS biomaterials science & engineering 2022 Feb 14;8(2):638-648
ACS biomaterials science & engineering 2022 Feb 14;8(2):638-648
METTL3 overexpression aggravates LPS-induced cellular inflammation in mouse intestinal epithelial cells and DSS-induced IBD in mice.
Yang L, Wu G, Wu Q, Peng L, Yuan L
Cell death discovery 2022 Feb 14;8(1):62
Cell death discovery 2022 Feb 14;8(1):62
Downregulation of macrophage migration inhibitory factor attenuates NLRP3 inflammasome mediated pyroptosis in sepsis-induced AKI.
Li T, Sun H, Li Y, Su L, Jiang J, Liu Y, Jiang N, Huang R, Zhang J, Peng Z
Cell death discovery 2022 Feb 14;8(1):61
Cell death discovery 2022 Feb 14;8(1):61
MiR-652-5p elevated glycolysis level by targeting TIGAR in T-cell acute lymphoblastic leukemia.
Liu S, Wang H, Guo W, Zhou X, Shu Y, Liu H, Yang L, Tang S, Su H, Liu Z, Zeng L, Zou L
Cell death & disease 2022 Feb 14;13(2):148
Cell death & disease 2022 Feb 14;13(2):148
ZHX2 inhibits thyroid cancer metastasis through transcriptional inhibition of S100A14.
Zhang Y, Sun M, Gao L, Liang X, Ma C, Lu J, Yue X
Cancer cell international 2022 Feb 12;22(1):76
Cancer cell international 2022 Feb 12;22(1):76
Comprehensive analysis of N(6)-methyladenosine regulators with the tumor immune landscape and correlation between the insulin-like growth factor 2 mRNA-binding protein 3 and programmed death ligand 1 in bladder cancer.
Cui J, Zhu Y, Liu X, Wang W, Jiang X, Xia Y, Zhou G, Chen S, Shi B
Cancer cell international 2022 Feb 11;22(1):72
Cancer cell international 2022 Feb 11;22(1):72
PEBP balances apoptosis and autophagy in whitefly upon arbovirus infection.
Wang S, Guo H, Zhu-Salzman K, Ge F, Sun Y
Nature communications 2022 Feb 11;13(1):846
Nature communications 2022 Feb 11;13(1):846
Development of a skin- and neuro-attenuated live vaccine for varicella.
Wang W, Pan D, Fu W, Ye X, Han J, Yang L, Jia J, Liu J, Zhu R, Zhang Y, Liu C, Ye J, Selariu A, Que Y, Zhao Q, Wu T, Li Y, Zhang J, Cheng T, Zhu H, Xia N
Nature communications 2022 Feb 11;13(1):824
Nature communications 2022 Feb 11;13(1):824
Overexpression of bmp4, dazl, nanos3 and sycp2 in Hu Sheep Leydig Cells Using CRISPR/dcas9 System Promoted Male Germ Cell Related Gene Expression.
Yang H, Deng M, Lv W, Wei Z, Cai Y, Cheng P, Wang F, Zhang Y
Biology 2022 Feb 11;11(2)
Biology 2022 Feb 11;11(2)
LncRNA MT1DP promotes cadmium-induced DNA replication stress by inhibiting chromatin recruitment of SMARCAL1.
Feng W, Qi Z, Dong Z, Liu W, Xu M, Gao M, Liu S
The Science of the total environment 2022 Feb 10;807(Pt 3):151078
The Science of the total environment 2022 Feb 10;807(Pt 3):151078
OGDHL ameliorates cognitive impairment and Alzheimer's disease-like pathology via activating Wnt/β-catenin signaling in Alzheimer's disease mice.
Yao L, Xu X, Xu Y, Li C, Xie F, Guo M, Liu Z, Liu X
Behavioural brain research 2022 Feb 10;418:113673
Behavioural brain research 2022 Feb 10;418:113673
Anti-fatigue effect of hypericin in a chronic forced exercise mouse model.
Sun Y, Liang C, Zheng L, Liu L, Li Z, Yang G, Li Y
Journal of ethnopharmacology 2022 Feb 10;284:114767
Journal of ethnopharmacology 2022 Feb 10;284:114767
FERMT1 contributes to the migration and invasion of nasopharyngeal carcinoma through epithelial-mesenchymal transition and cell cycle arrest.
Li L, Li P, Zhang W, Zhou H, Guo E, Hu G, Zhang L
Cancer cell international 2022 Feb 10;22(1):70
Cancer cell international 2022 Feb 10;22(1):70
Immune-responsive gene 1/itaconate activates nuclear factor erythroid 2-related factor 2 in microglia to protect against spinal cord injury in mice.
Ni L, Xiao J, Zhang D, Shao Z, Huang C, Wang S, Wu Y, Tian N, Sun L, Wu A, Zhou Y, Wang X, Zhang X
Cell death & disease 2022 Feb 10;13(2):140
Cell death & disease 2022 Feb 10;13(2):140
LncRNA Tug1 maintains blood-testis barrier integrity by modulating Ccl2 expression in high-fat diet mice.
Wang S, Qian Z, Ge X, Li C, Xue M, Liang K, Ma R, Ouyang L, Zheng L, Jing J, Cao S, Zhang Y, Yang Y, Chen Y, Ma J, Yao B
Cellular and molecular life sciences : CMLS 2022 Feb 1;79(2):114
Cellular and molecular life sciences : CMLS 2022 Feb 1;79(2):114
Grass Carp Reovirus Nonstructural Proteins Avoid Host Antiviral Immune Response by Targeting the RLR Signaling Pathway.
Zhang J, Man Wu X, Fang Q, Bi YH, Nie P, Chang MX
Journal of immunology (Baltimore, Md. : 1950) 2022 Feb 1;208(3):707-719
Journal of immunology (Baltimore, Md. : 1950) 2022 Feb 1;208(3):707-719
An alternatively spliced STING isoform localizes in the cytoplasmic membrane and directly senses extracellular cGAMP.
Li X, Zhu Y, Zhang X, An X, Weng M, Shi J, Wang S, Liu C, Luo S, Zheng T
The Journal of clinical investigation 2022 Feb 1;132(3)
The Journal of clinical investigation 2022 Feb 1;132(3)
A biomimetic nanodrug self-assembled from small molecules for enhanced ferroptosis therapy.
Xu X, Chen Y, Gui J, Liu P, Huang Y, Shao B, Ping Y, Li B
Biomaterials science 2022 Feb 1;10(3):770-780
Biomaterials science 2022 Feb 1;10(3):770-780
Maternal sevoflurane exposure affects neural stem cell differentiation in offspring rats through NRF2 signaling.
Zhang Y, Kuai S, Zhang Y, Xue H, Wu Z, Zhao P
Neurotoxicology 2022 Dec;93:348-354
Neurotoxicology 2022 Dec;93:348-354
Blockade of Nuclear β-Catenin Signaling via Direct Targeting of RanBP3 with NU2058 Induces Cell Senescence to Suppress Colorectal Tumorigenesis.
Zheng CC, Liao L, Liu YP, Yang YM, He Y, Zhang GG, Li SJ, Liu T, Xu WW, Li B
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2022 Dec;9(34):e2202528
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2022 Dec;9(34):e2202528
Lactobacillus reuteri normalizes altered fear memory in male Cntnap4 knockout mice.
Zhang W, Huang J, Gao F, You Q, Ding L, Gong J, Zhang M, Ma R, Zheng S, Sun X, Zhang Y
EBioMedicine 2022 Dec;86:104323
EBioMedicine 2022 Dec;86:104323
Leukemia inhibitory factor is a therapeutic target for renal interstitial fibrosis.
Xu S, Yang X, Chen Q, Liu Z, Chen Y, Yao X, Xiao A, Tian J, Xie L, Zhou M, Hu Z, Zhu F, Xu X, Hou F, Nie J
EBioMedicine 2022 Dec;86:104312
EBioMedicine 2022 Dec;86:104312
A signalling pathway for transcriptional regulation of sleep amount in mice.
Zhou R, Wang G, Li Q, Meng F, Liu C, Gan R, Ju D, Liao M, Xu J, Sang D, Gao X, Zhou S, Wu K, Sun Q, Guo Y, Wu C, Chen Z, Chen L, Shi B, Wang H, Wang X, Li H, Cai T, Li B, Wang F, Funato H, Yanagisawa M, Zhang EE, Liu Q
Nature 2022 Dec;612(7940):519-527
Nature 2022 Dec;612(7940):519-527
PPP1R14D promotes the proliferation, migration and invasion of lung adenocarcinoma via the PKCα/BRAF/MEK/ERK signaling pathway.
Cao H, Wang Z, Wang Y, Ye L, Li R, Xue Y, Li K, Di T, Li T, Fan Z, Liu Y, Guo J, Yao H, Ge C
International journal of oncology 2022 Dec;61(6)
International journal of oncology 2022 Dec;61(6)
Red ginseng polysaccharide exhibits anticancer activity through GPX4 downregulation-induced ferroptosis.
Zhai FG, Liang QC, Wu YY, Liu JQ, Liu JW
Pharmaceutical biology 2022 Dec;60(1):909-914
Pharmaceutical biology 2022 Dec;60(1):909-914
Baicalin protects against renal interstitial fibrosis in mice by inhibiting the TGF-β/Smad signalling pathway.
Wang H, Jiang Q, Zhang L
Pharmaceutical biology 2022 Dec;60(1):1407-1416
Pharmaceutical biology 2022 Dec;60(1):1407-1416
SRT1720 as an SIRT1 activator for alleviating paraquat-induced models of Parkinson's disease.
Chao CC, Huang CL, Cheng JJ, Chiou CT, Lee IJ, Yang YC, Hsu TH, Yei CE, Lin PY, Chen JJ, Huang NK
Redox biology 2022 Dec;58:102534
Redox biology 2022 Dec;58:102534
Mitochondrial DNA mediates immunoparalysis of dendritic cells in sepsis via STING signalling.
Tu Q, Li Y, Zhu J, Guo L, Liu C, Liu L, Yuan Y, Zou Y, Chen F, Yao L, Li J
Cell proliferation 2022 Dec;55(12):e13328
Cell proliferation 2022 Dec;55(12):e13328
Knockdown of ZBTB11 impedes R-loop elimination and increases the sensitivity to cisplatin by inhibiting DDX1 transcription in bladder cancer.
Chen L, Liu Z, Tang H, Zhou Z, Chen J, Ma Z, Deng M, Li X, Wu Y, Zheng L, Zhou L, Zheng X, Liu Z
Cell proliferation 2022 Dec;55(12):e13325
Cell proliferation 2022 Dec;55(12):e13325
ALA-PDT regulates macrophage M1 polarization via ERK/MAPK-NLRP3 pathway to promote the early inflammatory response.
Wang L, Zhang W, Cen R, Yue C, Xiao T, Deng Y, Li L, Sun K, Lei X
Lasers in surgery and medicine 2022 Dec;54(10):1309-1320
Lasers in surgery and medicine 2022 Dec;54(10):1309-1320
Characterization and functional analysis of lncRNA2690 in regulating the growth cycle of the hair follicle in rabbits.
Bao Z, Zhai P, Yao F, Ren Y, Zhao B, Chen Y, Wu X
Animal genetics 2022 Dec;53(6):841-848
Animal genetics 2022 Dec;53(6):841-848
Bone marrow-derived mesenchymal stem cells ameliorate severe acute pancreatitis by inhibiting oxidative stress in rats.
Zhao D, Yu W, Xie W, Ma Z, Hu Z, Song Z
Molecular and cellular biochemistry 2022 Dec;477(12):2761-2771
Molecular and cellular biochemistry 2022 Dec;477(12):2761-2771
FAT1 downregulation enhances stemness and cisplatin resistance in esophageal squamous cell carcinoma.
Zhai Y, Shan C, Zhang H, Kong P, Zhang L, Wang Y, Hu X, Cheng X
Molecular and cellular biochemistry 2022 Dec;477(12):2689-2702
Molecular and cellular biochemistry 2022 Dec;477(12):2689-2702
Bone marrow mesenchymal stem cells-derived exosomes mediate nuclear receptor coactivator-3 expression in osteoblasts by delivering miR-532-5p to influence osteonecrosis of the femoral head development.
Lan X, Ma H, Xiong Y, Zou L, Yuan Z, Xiao Y
Cell biology international 2022 Dec;46(12):2185-2197
Cell biology international 2022 Dec;46(12):2185-2197
Expression analysis of irisin during different development stages of skeletal muscle in mice.
Yan Y, Yang D, Wen P, Li Y, Ge Y, Ma P, Yuan J, Zhang P, Zhu Z, Luo X, Yu X, Wang H
Gene expression patterns : GEP 2022 Dec;46:119287
Gene expression patterns : GEP 2022 Dec;46:119287
Modulation of Microglia M2 Polarization and Alleviation of Hippocampal Neuron Injury By MiR-106b-5p/RGMa in a Mouse Model of Status Epilepticus.
Yu T, Huo L, Lei J, Sun JJ, Wang H
Inflammation 2022 Dec;45(6):2223-2242
Inflammation 2022 Dec;45(6):2223-2242
Inhibition of Circ-Snrk ameliorates apoptosis and inflammation in acute kidney injury by regulating the MAPK pathway.
Meng F, Chen Q, Gu S, Cui R, Ma Q, Cao R, Zhao M
Renal failure 2022 Dec;44(1):672-681
Renal failure 2022 Dec;44(1):672-681
ATG5-Mediated Autophagy May Inhibit Pyroptosis to Ameliorate Oleic Acid-Induced Hepatocyte Steatosis.
Tang Q, Liu W, Yang X, Tian Y, Chen J, Hu Y, Fu N
DNA and cell biology 2022 Dec;41(12):1038-1052
DNA and cell biology 2022 Dec;41(12):1038-1052
Brentuxinmab vedotin, alone or combine with bendamustine in the treatment of natural killer T cell lymphoma.
Zhang P, Shi C, Song Y, Li Z, Zhang M, Jin M
Hematological oncology 2022 Dec;40(5):941-952
Hematological oncology 2022 Dec;40(5):941-952
Di(2-ethylhexyl) phthalate induced thyroid toxicity via endoplasmic reticulum stress: In vivo and in vitro study.
Xu Q, Zhao T, Ri H, Ye J, Zhao W, Zhang Y, Ye L
Environmental toxicology 2022 Dec;37(12):2924-2936
Environmental toxicology 2022 Dec;37(12):2924-2936
Design, synthesis, and cytotoxic activities of isaindigotone derivatives as potential anti-gastric cancer agents.
Du K, Ma W, Yang C, Zhou Z, Hu S, Tian Y, Zhang H, Ma Y, Jiang X, Zhu H, Liu H, Chen P, Liu Y
Journal of enzyme inhibition and medicinal chemistry 2022 Dec;37(1):1212-1226
Journal of enzyme inhibition and medicinal chemistry 2022 Dec;37(1):1212-1226
Deciphering the map of METTL14-mediated lncRNA m6A modification at the transcriptome-wide level in breast cancer.
Yi D, Xu F, Wang R, Jiang C, Qin J, Lee Y, Shi X, Sang J
Journal of clinical laboratory analysis 2022 Dec;36(12):e24754
Journal of clinical laboratory analysis 2022 Dec;36(12):e24754
Mitochondrial dynamics, Leydig cell function, and age-related testosterone deficiency.
Garza S, Chen L, Galano M, Cheung G, Sottas C, Li L, Li Y, Zirkin BR, Papadopoulos V
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2022 Dec;36(12):e22637
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2022 Dec;36(12):e22637
WTAP dysregulation-mediated HMGN3-m6A modification inhibited trophoblast invasion in early-onset preeclampsia.
Bian Y, Li J, Shen H, Li Y, Hou Y, Huang L, Song G, Qiao C
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2022 Dec;36(12):e22617
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2022 Dec;36(12):e22617
BDE-47 disturbs the immune response of lymphocytes to LPS by downregulating NF-κB pathway.
Xue D, Wei J, Lu W, Xia B, Li S, Liu D, Liu N, Wang X, Lin G
Chemosphere 2022 Dec;308(Pt 3):136562
Chemosphere 2022 Dec;308(Pt 3):136562
The interaction between E3 ubiquitin ligase Parkin and mitophagy receptor PHB2 links inner mitochondrial membrane ubiquitination to efficient mitophagy.
Sun S, Hou H, Ma G, Ma Q, Li N, Zhang L, Dong C, Cao M, Tam KY, Ying Z, Wang H
The Journal of biological chemistry 2022 Dec;298(12):102704
The Journal of biological chemistry 2022 Dec;298(12):102704
OCA7 is a melanosome membrane protein that defines pigmentation by regulating early stages of melanosome biogenesis.
Beyers WC, Detry AM, Di Pietro SM
The Journal of biological chemistry 2022 Dec;298(12):102669
The Journal of biological chemistry 2022 Dec;298(12):102669
Cartwheel disassembly regulated by CDK1-cyclin B kinase allows human centriole disengagement and licensing.
Huang F, Xu X, Xin G, Zhang B, Jiang Q, Zhang C
The Journal of biological chemistry 2022 Dec;298(12):102658
The Journal of biological chemistry 2022 Dec;298(12):102658
Lonidamine and domperidone inhibit expansion of transformed cell areas by modulating motility of surrounding nontransformed cells.
Aoyama M, Ishikawa K, Nemoto S, Hirano H, Watanabe N, Osada H, Watanabe S, Semba K
The Journal of biological chemistry 2022 Dec;298(12):102635
The Journal of biological chemistry 2022 Dec;298(12):102635
Glucose-6-phosphate dehydrogenase exerts antistress effects independently of its enzymatic activity.
Jin X, Li X, Li L, Zhong B, Hong Y, Niu J, Li B
The Journal of biological chemistry 2022 Dec;298(12):102587
The Journal of biological chemistry 2022 Dec;298(12):102587
Development of nanocubosomes co-loaded with dual anticancer agents curcumin and temozolomide for effective Colon cancer therapy.
Almoshari Y, Iqbal H, Razzaq A, Ali Ahmad K, Khan MK, Saeed Alqahtani S, Hadi Sultan M, Ali Khan B
Drug delivery 2022 Dec;29(1):2633-2643
Drug delivery 2022 Dec;29(1):2633-2643
A recombinant scFv antibody-based fusion protein that targets EGFR associated with IMPDH2 downregulation and its drug conjugate show therapeutic efficacy against esophageal cancer.
He S, Zhao C, Tao H, Sheng W, Gao R, Liu X, Zhen Y
Drug delivery 2022 Dec;29(1):1243-1256
Drug delivery 2022 Dec;29(1):1243-1256
LRPPRC inhibits autophagy and promotes foam cell formation in atherosclerosis.
Xu Z, Li X, Ding Z, Zhang Y, Peng Z, Yang X, Cao W, Du R
The FEBS journal 2022 Dec;289(23):7545-7560
The FEBS journal 2022 Dec;289(23):7545-7560
Ferroptosis contributes to hypoxic-ischemic brain injury in neonatal rats: Role of the SIRT1/Nrf2/GPx4 signaling pathway.
Li C, Wu Z, Xue H, Gao Q, Zhang Y, Wang C, Zhao P
CNS neuroscience & therapeutics 2022 Dec;28(12):2268-2280
CNS neuroscience & therapeutics 2022 Dec;28(12):2268-2280
CircHOMER1 aggravates oxidative stress, inflammation and extracellular matrix deposition in high glucose-induced human mesangial cells.
Shu S, Xu Z, Lu H, Li Z, Zhang Y
Nephrology (Carlton, Vic.) 2022 Dec;27(12):983-993
Nephrology (Carlton, Vic.) 2022 Dec;27(12):983-993
SPRY1 promotes cell proliferation and inhibits apoptosis by activating Hedgehog pathway in acute myeloid leukemia.
Lv G, Wang Y, Ji C, Shi C, Li Y
Hematology (Amsterdam, Netherlands) 2022 Dec;27(1):1-10
Hematology (Amsterdam, Netherlands) 2022 Dec;27(1):1-10
CUL4B increases platinum-based drug resistance in colorectal cancer through EMT: A study in its mechanism.
Luo JW, Wang CM, Su JW, Yi TZ, Tang SH
Journal of cellular and molecular medicine 2022 Dec;26(23):5767-5778
Journal of cellular and molecular medicine 2022 Dec;26(23):5767-5778
Autoantibody panel on small extracellular vesicles for the early detection of lung cancer.
Hua Y, Dai C, He Q, Cai X, Li M
Clinical immunology (Orlando, Fla.) 2022 Dec;245:109175
Clinical immunology (Orlando, Fla.) 2022 Dec;245:109175
Endothelial cell-derived S1P promotes migration and stemness by binding with GPR63 in colorectal cancer.
Zeng S, Liang Y, Hu H, Wang F, Liang L
Pathology, research and practice 2022 Dec;240:154197
Pathology, research and practice 2022 Dec;240:154197
Monocytes deposit migrasomes to promote embryonic angiogenesis.
Zhang C, Li T, Yin S, Gao M, He H, Li Y, Jiang D, Shi M, Wang J, Yu L
Nature cell biology 2022 Dec;24(12):1726-1738
Nature cell biology 2022 Dec;24(12):1726-1738
Atg9A-mediated mitophagy is required for decidual differentiation of endometrial stromal cells.
Li J, Zhang S, Zhang Y, Dai Y, Zhang Y, Yang A, Hong F, Pan Y
Reproductive biology 2022 Dec;22(4):100707
Reproductive biology 2022 Dec;22(4):100707
Melatonin enhances spermatogonia activity through promoting KIAA1429-mediated m(6)A deposition to activate the PI3K/AKT signaling.
Xu CL, Tan QY, Yang H, Li CY, Wu Z, Ma YF
Reproductive biology 2022 Dec;22(4):100681
Reproductive biology 2022 Dec;22(4):100681
Advanced glycation end products induce senescence of atrial myocytes and increase susceptibility of atrial fibrillation in diabetic mice.
Zheng DL, Wu QR, Zeng P, Li SM, Cai YJ, Chen SZ, Luo XS, Kuang SJ, Rao F, Lai YY, Zhou MY, Wu FL, Yang H, Deng CY
Aging cell 2022 Dec;21(12):e13734
Aging cell 2022 Dec;21(12):e13734
Daidzein Activates Akt Pathway to Promote the Proliferation of Female Germline Stem Cells through Upregulating Clec11a.
Li F, Hu X, Wu J
Stem cell reviews and reports 2022 Dec;18(8):3021-3032
Stem cell reviews and reports 2022 Dec;18(8):3021-3032
WIPI2 positively regulates mitophagy by promoting mitochondrial recruitment of VCP.
Lu G, Tan HWS, Schmauck-Medina T, Wang L, Chen J, Cho YL, Chen K, Zhang JZ, He W, Wu Y, Xia D, Zhou J, Fang EF, Fang L, Liu W, Shen HM
Autophagy 2022 Dec;18(12):2865-2879
Autophagy 2022 Dec;18(12):2865-2879
KAT7-mediated CANX (calnexin) crotonylation regulates leucine-stimulated MTORC1 activity.
Yan G, Li X, Zheng Z, Gao W, Chen C, Wang X, Cheng Z, Yu J, Zou G, Farooq MZ, Zhu X, Zhu W, Zhong Q, Yan X
Autophagy 2022 Dec;18(12):2799-2816
Autophagy 2022 Dec;18(12):2799-2816
Defective autophagy triggered by arterial cyclic stretch promotes neointimal hyperplasia in vein grafts via the p62/nrf2/slc7a11 signaling pathway.
Chen Y, Bao M, Liu JT, Bao H, Zhang SM, Lou Y, Qi YX
Journal of molecular and cellular cardiology 2022 Dec;173:101-114
Journal of molecular and cellular cardiology 2022 Dec;173:101-114
Differential regulatory roles of microRNAs during intramuscular adipogenesis in Chinese Guizhou Congjiang Xiang pigs.
Tan L, Chen Z, Ruan Y, Xu H
Epigenetics 2022 Dec;17(12):1800-1819
Epigenetics 2022 Dec;17(12):1800-1819
Selective targeting of visceral adiposity by polycation nanomedicine.
Wan Q, Huang B, Li T, Xiao Y, He Y, Du W, Wang BZ, Dakin GF, Rosenbaum M, Goncalves MD, Chen S, Leong KW, Qiang L
Nature nanotechnology 2022 Dec;17(12):1311-1321
Nature nanotechnology 2022 Dec;17(12):1311-1321
Coptisine protects against hyperuricemic nephropathy through alleviating inflammation, oxidative stress and mitochondrial apoptosis via PI3K/Akt signaling pathway.
Liu Y, Gong S, Li K, Wu G, Zheng X, Zheng J, Lu X, Zhang L, Li J, Su Z, Liu Y, Xie J, Chen J, Li Y
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Dec;156:113941
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Dec;156:113941
Mesenchymal stem cell-derived extracellular vesicles attenuate tPA-induced blood-brain barrier disruption in murine ischemic stroke models.
Qiu L, Cai Y, Geng Y, Yao X, Wang L, Cao H, Zhang X, Wu Q, Kong D, Ding D, Shi Y, Wang Y, Wu J
Acta biomaterialia 2022 Dec;154:424-442
Acta biomaterialia 2022 Dec;154:424-442
A functionalized collagen-I scaffold delivers microRNA 21-loaded exosomes for spinal cord injury repair.
Liu X, Zhang L, Xu Z, Xiong X, Yu Y, Wu H, Qiao H, Zhong J, Zhao Z, Dai J, Suo G
Acta biomaterialia 2022 Dec;154:385-400
Acta biomaterialia 2022 Dec;154:385-400
Characterization of Cornulin as a Molecular Biomarker for the Progression of Oral Squamous Cell Carcinoma.
Kerdjoudj M, Arnouk H
Cureus 2022 Dec;14(12):e32210
Cureus 2022 Dec;14(12):e32210
The miRNA125a-5p and miRNA125b-1-5p cluster induces cell invasion by down-regulating DDB2-reduced epithelial-to-mesenchymal transition (EMT) in colorectal cancer.
Zhu F, Wei J, He D, He J, Liu L, Hou H, Shi H, Jin S, Li J, Shi X, Liu P, Huang M
Journal of gastrointestinal oncology 2022 Dec;13(6):3112-3122
Journal of gastrointestinal oncology 2022 Dec;13(6):3112-3122
PRRX1 promotes colorectal cancer stemness and chemoresistance via the JAK2/STAT3 axis by targeting IL-6.
Zhong L, Tan W, Yang Q, Zou Z, Zhou R, Huang Y, Qiu Z, Zheng K, Huang Z
Journal of gastrointestinal oncology 2022 Dec;13(6):2989-3008
Journal of gastrointestinal oncology 2022 Dec;13(6):2989-3008
Maternal rodent exposure to di-(2-ethylhexyl) phthalate decreases muscle mass in the offspring by increasing myostatin.
Li F, Luo T, Rong H, Lu L, Zhang L, Zheng C, Yi D, Peng Y, Lei E, Xiong X, Wang F, Garcia JM, Chen JA
Journal of cachexia, sarcopenia and muscle 2022 Dec;13(6):2740-2751
Journal of cachexia, sarcopenia and muscle 2022 Dec;13(6):2740-2751
AP-1 signaling pathway promotes pro-IL-1β transcription to facilitate NLRP3 inflammasome activation upon influenza A virus infection.
Wan P, Zhang S, Ruan Z, Liu X, Yang G, Jia Y, Li Y, Pan P, Wang W, Li G, Chen X, Liu Z, Zhang Q, Luo Z, Wu J
Virulence 2022 Dec;13(1):502-513
Virulence 2022 Dec;13(1):502-513
Inhibition of cell proliferation by Tas of foamy viruses through cell cycle arrest or apoptosis underlines the different mechanisms of virus-host interactions.
Jie W, Rui-Fen Z, Zhong-Xiang H, Yan W, Wei-Na L, Yong-Ping M, Jing S, Jing-Yi C, Wan-Hong L, Xiao-Hua H, Zhi L, Yan S
Virulence 2022 Dec;13(1):342-354
Virulence 2022 Dec;13(1):342-354
Regulation of host factor γ-H2AX level and location by enterovirus A71 for viral replication.
Yu J, Zhang W, Huo W, Meng X, Zhong T, Su Y, Liu Y, Liu J, Wang Z, Song F, Zhang S, Li Z, Yu X, Yu X, Hua S
Virulence 2022 Dec;13(1):241-257
Virulence 2022 Dec;13(1):241-257
Natural carbazole alkaloid murrayafoline A displays potent anti-neuroinflammatory effect by directly targeting transcription factor Sp1 in LPS-induced microglial cells.
Li CH, Zhou Y, Tu PF, Zeng KW, Jiang Y
Bioorganic chemistry 2022 Dec;129:106178
Bioorganic chemistry 2022 Dec;129:106178
Corynoxine suppresses pancreatic cancer growth primarily via ROS-p38 mediated cytostatic effects.
Wen C, Ruan Q, Li Z, Zhou X, Yang X, Xu P, Akuetteh PDP, Xu Z, Deng J
British journal of cancer 2022 Dec;127(12):2108-2117
British journal of cancer 2022 Dec;127(12):2108-2117
The function of FUS in neurodevelopment revealed by the brain and spinal cord organoids.
Zou H, Wang JY, Ma GM, Xu MM, Luo F, Zhang L, Wang WY
Molecular and cellular neurosciences 2022 Dec;123:103771
Molecular and cellular neurosciences 2022 Dec;123:103771
Sphingosine kinase 1 promotes growth of glioblastoma by increasing inflammation mediated by the NF-κB /IL-6/STAT3 and JNK/PTX3 pathways.
Li W, Cai H, Ren L, Yang Y, Yang H, Liu J, Li S, Zhang Y, Zheng X, Tan W, Du G, Wang J
Acta pharmaceutica Sinica. B 2022 Dec;12(12):4390-4406
Acta pharmaceutica Sinica. B 2022 Dec;12(12):4390-4406
Myoblast-derived exosomes promote the repair and regeneration of injured skeletal muscle in mice.
Ji S, Ma P, Cao X, Wang J, Yu X, Luo X, Lu J, Hou W, Zhang Z, Yan Y, Dong Y, Wang H
FEBS open bio 2022 Dec;12(12):2213-2226
FEBS open bio 2022 Dec;12(12):2213-2226
Epoxymicheliolide prevents dextran sulfate sodium-induced colitis in mice by inhibiting TAK1-NF-κB pathway and activating Keap1-NRF2 signaling in macrophages.
He J, Liu L, Liu X, Chen H, Liu K, Huang N, Wang Y
International immunopharmacology 2022 Dec;113(Pt A):109404
International immunopharmacology 2022 Dec;113(Pt A):109404
Eplerenone inhibits the macrophage-to-myofibroblast transition in rats with UUO-induced type 4 cardiorenal syndrome through the MR/CTGF pathway.
Han Y, Xian Y, Gao X, Qiang P, Hao J, Yang F, Shimosawa T, Chang Y, Xu Q
International immunopharmacology 2022 Dec;113(Pt A):109396
International immunopharmacology 2022 Dec;113(Pt A):109396
β-carotene alleviates LPS-induced inflammation through regulating STIM1/ORAI1 expression in bovine mammary epithelial cells.
Meng M, Huo R, Ma N, Chang G, Shen X
International immunopharmacology 2022 Dec;113(Pt A):109377
International immunopharmacology 2022 Dec;113(Pt A):109377
Mefunidone ameliorates lipopolysaccharide-induced acute lung injury through inhibiting MAPK signaling pathway and enhancing Nrf2 pathway.
Yao TT, Zhang Y, He RL, Lv X, He YJ, Li MY, Han YY, Long LZ, Jiang GL, Cheng XY, Hu GY, Li QB, Tao LJ, Meng J
International immunopharmacology 2022 Dec;113(Pt A):109263
International immunopharmacology 2022 Dec;113(Pt A):109263
Isolongifolene alleviates liver ischemia/reperfusion injury by regulating AMPK-PGC1α signaling pathway-mediated inflammation, apoptosis, and oxidative stress.
Li J, Li J, Fang H, Yang H, Wu T, Shi X, Pang C
International immunopharmacology 2022 Dec;113(Pt A):109185
International immunopharmacology 2022 Dec;113(Pt A):109185
Myostatin increases the expression of matrix metalloproteinase genes to promote preadipocytes differentiation in pigs.
Zhu Z, Ali A, Wang J, Qi S, Hua Z, Ren H, Zhang L, Gu H, Molenaar A, Babar ME, Bi Y
Adipocyte 2022 Dec;11(1):266-275
Adipocyte 2022 Dec;11(1):266-275
The combination of nuclear receptor NR1D1 and ULK1 promotes mitophagy in adipocytes to ameliorate obesity.
Yu B, Pan JB, Yu FY
Adipocyte 2022 Dec;11(1):202-212
Adipocyte 2022 Dec;11(1):202-212
Gut dysbacteriosis attenuates resistance to Mycobacterium bovis infection by decreasing cyclooxygenase 2 to inhibit endoplasmic reticulum stress.
Wang H, Yao J, Chen Y, Wang Y, Liu Y, Liao Y, Liang Z, Dong YH, Qu M, Ge X, Zhou X
Emerging microbes & infections 2022 Dec;11(1):1806-1818
Emerging microbes & infections 2022 Dec;11(1):1806-1818
Posttranscriptional inhibition of γ-adducin promotes the proliferation and migration of osteosarcoma cells.
Suo Z, Ma X, Ding Y, Zhou Y, Duan X, Fei L, Song J, Ding H
Tumori 2022 Dec;108(6):600-608
Tumori 2022 Dec;108(6):600-608
Phellopterin cream exerts an anti-inflammatory effect that facilitates diabetes-associated cutaneous wound healing via SIRT1.
Zou J, Duan Y, Wang Y, Liu A, Chen Y, Guo D, Guo W, Li S, Su Z, Wu Y, Lu H, Deng Y, Zhu J, Li F
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Dec;107:154447
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Dec;107:154447
Near-infrared light-triggered polypyrrole promotes C2C12 cell differentiation and inhibits TNF-α induced myotube atrophy.
Wu Y, Che J, Jia P, Ma Y, Han Q, Wang X, Fu L, Dou H, Zheng Y
Cellular signalling 2022 Dec;100:110463
Cellular signalling 2022 Dec;100:110463
Yishen Xiezhuo formula ameliorates the development of cisplatin-induced acute kidney injury by attenuating renal tubular epithelial cell senescence.
Zhang Q, Qi J, Luo Q, Wu M, Zhang L, Qin L, Nie X
Annals of translational medicine 2022 Dec;10(24):1392
Annals of translational medicine 2022 Dec;10(24):1392
RNA granule-clustered mitochondrial aminoacyl-tRNA synthetases form multiple complexes with the potential to fine-tune tRNA aminoacylation.
Peng GX, Mao XL, Cao Y, Yao SY, Li QR, Chen X, Wang ED, Zhou XL
Nucleic acids research 2022 Dec 9;50(22):12951-12968
Nucleic acids research 2022 Dec 9;50(22):12951-12968
Elsholtzia bodinieri Vaniot Ameliorated Acute Lung Injury by NQO1, BCL2 and PTGS2 In Silico and In Vitro Analyses.
Sun J, Jiang X, Chen Y, Guo S, Zhao Z, Cao J, Liu Y, Cheng G, Li Y, Tian L
International journal of molecular sciences 2022 Dec 9;23(24)
International journal of molecular sciences 2022 Dec 9;23(24)
GATOR2-dependent mTORC1 activity is a therapeutic vulnerability in FOXO1 fusion-positive rhabdomyosarcoma.
Morales J, Allegakoen DV, Garcia JA, Kwong K, Sahu PK, Fajardo DA, Pan Y, Horlbeck MA, Weissman JS, Gustafson WC, Bivona TG, Sabnis AJ
JCI insight 2022 Dec 8;7(23)
JCI insight 2022 Dec 8;7(23)
The A-to-I editing of KPC1 promotes intrahepatic cholangiocarcinoma by attenuating proteasomal processing of NF-κB1 p105 to p50.
Gao C, Zhou G, Shi J, Shi P, Jin L, Li Y, Wang X, Liao S, Yan H, Wu J, Lu Y, Zhai Y, Zhang J, Zhang H, Zhang H, Yang C, Cao P, Cheng S, Zhou G
Journal of experimental & clinical cancer research : CR 2022 Dec 8;41(1):338
Journal of experimental & clinical cancer research : CR 2022 Dec 8;41(1):338
METTL3 promotes glycolysis and cholangiocarcinoma progression by mediating the m6A modification of AKR1B10.
Cai J, Cui Z, Zhou J, Zhang B, Lu R, Ding Y, Hu H
Cancer cell international 2022 Dec 7;22(1):385
Cancer cell international 2022 Dec 7;22(1):385
The chromatin remodeler CHD6 promotes colorectal cancer development by regulating TMEM65-mediated mitochondrial dynamics via EGF and Wnt signaling.
Zhang B, Liu Q, Wen W, Gao H, Wei W, Tang A, Qin B, Lyu H, Meng X, Li K, Jin H, Yu F, Pan Q, Lin J, Lee MH
Cell discovery 2022 Dec 6;8(1):130
Cell discovery 2022 Dec 6;8(1):130
USP32-regulated LAMTOR1 ubiquitination impacts mTORC1 activation and autophagy induction.
Hertel A, Alves LM, Dutz H, Tascher G, Bonn F, Kaulich M, Dikic I, Eimer S, Steinberg F, Bremm A
Cell reports 2022 Dec 6;41(10):111653
Cell reports 2022 Dec 6;41(10):111653
A novel small compound TOIDC suppresses lipogenesis via SREBP1-dependent signaling to curb MAFLD.
Shao Y, Yao Z, Zhou J, Yu M, Chen S, Yuan Y, Han L, Jiang L, Liu J
Nutrition & metabolism 2022 Dec 6;19(1):80
Nutrition & metabolism 2022 Dec 6;19(1):80
Death Receptor DR5 as a Proviral Factor for Viral Entry and Replication of Coronavirus PEDV.
Zhang XZ, Tian WJ, Wang J, You JL, Wang XJ
Viruses 2022 Dec 6;14(12)
Viruses 2022 Dec 6;14(12)
Extracellular traps from activated vascular smooth muscle cells drive the progression of atherosclerosis.
Zhai M, Gong S, Luan P, Shi Y, Kou W, Zeng Y, Shi J, Yu G, Hou J, Yu Q, Jian W, Zhuang J, Feinberg MW, Peng W
Nature communications 2022 Dec 6;13(1):7500
Nature communications 2022 Dec 6;13(1):7500
Role of cardiac mitofusins in cardiac conduction following simulated ischemia-reperfusion.
Kwek XY, Hall AR, Lim WW, Katwadi K, Soong PL, Grishina E, Lin KH, Crespo-Avilan G, Yap EP, Ismail NI, Chinda K, Chung YY, Wei H, Shim W, Montaigne D, Tinker A, Ong SB, Hausenloy DJ
Scientific reports 2022 Dec 6;12(1):21049
Scientific reports 2022 Dec 6;12(1):21049
ITGA5 inhibition in pancreatic stellate cells re-educates the in vitro tumor-stromal crosstalk.
Wang T, Yang J, Mao J, Zhu L, Luo X, Cheng C, Zhang L
Medical oncology (Northwood, London, England) 2022 Dec 5;40(1):39
Medical oncology (Northwood, London, England) 2022 Dec 5;40(1):39
A Regulatory Loop Involving miR-200c and NF-κB Modulates Mortalin Expression and Increases Cisplatin Sensitivity in an Ovarian Cancer Cell Line Model.
Huang X, Yan Y, Gui A, Zhu S, Qiu S, Chen F, Liu W, Zuo J, Yang L
International journal of molecular sciences 2022 Dec 4;23(23)
International journal of molecular sciences 2022 Dec 4;23(23)
Toosendanin Induces Hepatocyte Damage by Inhibiting Autophagic Flux via TFEB-Mediated Lysosomal Dysfunction.
Luo L, Liang Y, Fu Y, Liang Z, Zheng J, Lan J, Shen F, Huang Z
Pharmaceuticals (Basel, Switzerland) 2022 Dec 3;15(12)
Pharmaceuticals (Basel, Switzerland) 2022 Dec 3;15(12)
Nucleophagic Degradation of Progerin Ameliorates Defenestration in Liver Sinusoidal Endothelium Due to SIRT1-Mediated Deacetylation of Nuclear LC3.
Bai Y, Liu J, Jiang X, Li X, Zhang B, Luo X
Cells 2022 Dec 3;11(23)
Cells 2022 Dec 3;11(23)
Exosomal IL-8 derived from Lung Cancer and Colon Cancer cells induced adipocyte atrophy via NF-κB signaling pathway.
Xiong H, Ye J, Xie K, Hu W, Xu N, Yang H
Lipids in health and disease 2022 Dec 29;21(1):147
Lipids in health and disease 2022 Dec 29;21(1):147
A Novel Mast Cell Stabilizer JM25-1 Rehabilitates Impaired Gut Barrier by Targeting the Corticotropin-Releasing Hormone Receptors.
Sun Y, Li H, Liu L, Bai X, Wu L, Shan J, Sun X, Wang Q, Guo Y
Pharmaceuticals (Basel, Switzerland) 2022 Dec 29;16(1)
Pharmaceuticals (Basel, Switzerland) 2022 Dec 29;16(1)
RNaseH2A downregulation drives inflammatory gene expression via genomic DNA fragmentation in senescent and cancer cells.
Sugawara S, Okada R, Loo TM, Tanaka H, Miyata K, Chiba M, Kawasaki H, Katoh K, Kaji S, Maezawa Y, Yokote K, Nakayama M, Oshima M, Nagao K, Obuse C, Nagayama S, Takubo K, Nakanishi A, Kanemaki MT, Hara E, Takahashi A
Communications biology 2022 Dec 28;5(1):1420
Communications biology 2022 Dec 28;5(1):1420
Effect of hypoxia on HIF-1α/MDR1/VEGF expression in gastric cancer cells treated with 5-fluorouracil.
Wang L, Xing W, Qi J, Lu Y, Xiang L, Zhou Y
Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences 2022 Dec 28;47(12):1629-1636
Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences 2022 Dec 28;47(12):1629-1636
Monkfish (Lophius litulon) Peptides Ameliorate High-Fat-Diet-Induced Nephrotoxicity by Reducing Oxidative Stress and Inflammation via Regulation of Intestinal Flora.
Ren X, Miao B, Cao H, Tian X, Shen L, Yang Z, Yuan F, Ding Y
Molecules (Basel, Switzerland) 2022 Dec 28;28(1)
Molecules (Basel, Switzerland) 2022 Dec 28;28(1)
Histone methyltransferase Smyd2 drives vascular aging by its enhancer-dependent activity.
Su Z, Su H, Xu J, Wei G, Qu L, Ni T, Yang D, Zhu Y
Aging 2022 Dec 28;15(1):70-91
Aging 2022 Dec 28;15(1):70-91
4EBP1 senses extracellular glucose deprivation and initiates cell death signaling in lung cancer.
Wang Y, Lei J, Zhang S, Wang X, Jin J, Liu Y, Gan M, Yuan Y, Sun L, Li X, Han T, Wang JB
Cell death & disease 2022 Dec 27;13(12):1075
Cell death & disease 2022 Dec 27;13(12):1075
U1 snRNP proteins promote proximal alternative polyadenylation sites by directly interacting with 3' end processing core factors.
Hu Z, Li M, Huo Z, Chen L, Liu S, Deng K, Lu X, Chen S, Fu Y, Xu A
Journal of molecular cell biology 2022 Dec 26;14(8)
Journal of molecular cell biology 2022 Dec 26;14(8)
Pharmacological inhibition of Lin28 promotes ketogenesis and restores lipid homeostasis in models of non-alcoholic fatty liver disease.
Lekka E, Kokanovic A, Mosole S, Civenni G, Schmidli S, Laski A, Ghidini A, Iyer P, Berk C, Behera A, Catapano CV, Hall J
Nature communications 2022 Dec 26;13(1):7940
Nature communications 2022 Dec 26;13(1):7940
Elabela: Negative Regulation of Ferroptosis in Trophoblasts via the Ferritinophagy Pathway Implicated in the Pathogenesis of Preeclampsia.
Yang H, Zhang X, Ding Y, Xiong H, Xiang S, Wang Y, Li H, Liu Z, He J, Tao Y, Yang H, Qi H
Cells 2022 Dec 26;12(1)
Cells 2022 Dec 26;12(1)
Involvement of pyroptosis pathway in epicardial adipose tissue - myocardium axis in experimental heart failure with preserved ejection fraction.
Xia YY, Shi Y, Li Z, Li H, Wu LD, Zhou WY, Gu Y, Ling ZY, Zhang JX, Chen SL
Biochemical and biophysical research communications 2022 Dec 25;636(Pt 2):62-70
Biochemical and biophysical research communications 2022 Dec 25;636(Pt 2):62-70
tRNA derived fragment tsRNA-14783 promotes M2 polarization of macrophages in keloid.
Wang X, Hu Z
Biochemical and biophysical research communications 2022 Dec 25;636(Pt 2):119-127
Biochemical and biophysical research communications 2022 Dec 25;636(Pt 2):119-127
Efficient TurboID-based proximity labelling method for identifying terminal sialic acid glycosylation in living cells.
Liu W, Long Y, Bao Y, Li Y, Deng M, Yang X, Zhu H, Su Y
Acta biochimica et biophysica Sinica 2022 Dec 25;54(12):1841-1853
Acta biochimica et biophysica Sinica 2022 Dec 25;54(12):1841-1853
IL-22 inhibits bleomycin-induced pulmonary fibrosis in association with inhibition of IL-17A in mice.
Qu Z, Dou W, Zhang K, Duan L, Zhou D, Yin S
Arthritis research & therapy 2022 Dec 24;24(1):280
Arthritis research & therapy 2022 Dec 24;24(1):280
C/D box small nucleolar RNA SNORD104 promotes endometrial cancer by regulating the 2'-O-methylation of PARP1.
Lu B, Chen X, Liu X, Chen J, Qin H, Chen S, Zhao Y
Journal of translational medicine 2022 Dec 24;20(1):618
Journal of translational medicine 2022 Dec 24;20(1):618
SLC1A5 enhances malignant phenotypes through modulating ferroptosis status and immune microenvironment in glioma.
Han L, Zhou J, Li L, Wu X, Shi Y, Cui W, Zhang S, Hu Q, Wang J, Bai H, Liu H, Guo C, Cao H, Chao M, Hu Y, Mou Y, Jiao Y, Feng D, Wang L, Qu Y
Cell death & disease 2022 Dec 24;13(12):1071
Cell death & disease 2022 Dec 24;13(12):1071
Diaporisoindole B Reduces Lipid Accumulation in THP-1 Macrophage Cells via MAPKs and PPARγ-LXRα Pathways and Promotes the Reverse Cholesterol Transport by Upregulating SR-B1 and LDLR in HepG2 Cells.
Liu H, Xie H, Li C, Wang L, Chen Q, Ouyang X, Yan C
Journal of natural products 2022 Dec 23;85(12):2769-2778
Journal of natural products 2022 Dec 23;85(12):2769-2778
Biofabrication of synthetic human liver tissue with advanced programmable functions.
Florentino RM, Morita K, Haep N, Motomura T, Diaz-Aragon R, Faccioli LAP, Collin de l'Hortet A, Cetin Z, Frau C, Vernetti L, Amler AK, Thomas A, Lam T, Kloke L, Takeishi K, Taylor DL, Fox IJ, Soto-Gutierrez A
iScience 2022 Dec 22;25(12):105503
iScience 2022 Dec 22;25(12):105503
Oryzanol Ameliorates DSS-Stimulated Gut Barrier Damage via Targeting the Gut Microbiota Accompanied by the TLR4/NF-κB/NLRP3 Cascade Response In Vivo.
Xia X, Lin H, Luo F, Wu X, Zhu L, Chen S, Luo H, Ye F, Peng X, Zhang Y, Yang G, Lin Q
Journal of agricultural and food chemistry 2022 Dec 21;70(50):15747-15762
Journal of agricultural and food chemistry 2022 Dec 21;70(50):15747-15762
The Zinc Finger Transcription Factor Fts2 Represses the Yeast-to-Filament Transition in the Dimorphic Yeast Yarrowia lipolytica.
Chen JW, Mao YS, Yan LQ, Gao XD
mSphere 2022 Dec 21;7(6):e0045022
mSphere 2022 Dec 21;7(6):e0045022
Huntington disease oligodendrocyte maturation deficits revealed by single-nucleus RNAseq are rescued by thiamine-biotin supplementation.
Lim RG, Al-Dalahmah O, Wu J, Gold MP, Reidling JC, Tang G, Adam M, Dansu DK, Park HJ, Casaccia P, Miramontes R, Reyes-Ortiz AM, Lau A, Hickman RA, Khan F, Paryani F, Tang A, Ofori K, Miyoshi E, Michael N, McClure N, Flowers XE, Vonsattel JP, Davidson S, Menon V, Swarup V, Fraenkel E, Goldman JE, Thompson LM
Nature communications 2022 Dec 21;13(1):7791
Nature communications 2022 Dec 21;13(1):7791
Discovery and mechanism studies of a novel ATG4B inhibitor Ebselen by drug repurposing and its anti-colorectal cancer effects in mice.
Xie H, Qiang P, Wang Y, Xia F, Liu P, Li M
Cell & bioscience 2022 Dec 21;12(1):206
Cell & bioscience 2022 Dec 21;12(1):206
Myo-Inositol Supplementation Alleviates Cisplatin-Induced Acute Kidney Injury via Inhibition of Ferroptosis.
Qi H, Deng F, Wang Y, Zhang H, Kanwar YS, Dai Y
Cells 2022 Dec 21;12(1)
Cells 2022 Dec 21;12(1)
Chemotherapeutic Drugs Induce Different Gut Microbiota Disorder Pattern and NOD/RIP2/NF-κB Signaling Pathway Activation That Lead to Different Degrees of Intestinal Injury.
Huang B, Gui M, Ni Z, He Y, Zhao J, Peng J, Lin J
Microbiology spectrum 2022 Dec 21;10(6):e0167722
Microbiology spectrum 2022 Dec 21;10(6):e0167722
Ubiquitination of SARS-CoV-2 ORF7a Prevents Cell Death Induced by Recruiting BclXL To Activate ER Stress.
Liu Z, Fu Y, Huang Y, Zeng F, Rao J, Xiao X, Sun X, Jin H, Li J, Yang J, Du W, Liu L
Microbiology spectrum 2022 Dec 21;10(6):e0150922
Microbiology spectrum 2022 Dec 21;10(6):e0150922
NLRP3 deficiency decreases alcohol intake controlling anxiety-like behavior via modification of glutamatergic transmission in corticostriatal circuits.
Li Z, Vidjro OE, Guo G, Du Y, Zhou Y, Xie Q, Li J, Gao K, Zhou L, Ma T
Journal of neuroinflammation 2022 Dec 20;19(1):308
Journal of neuroinflammation 2022 Dec 20;19(1):308
Irisin promotes the browning of white adipocytes tissue by AMPKα1 signaling pathway.
Luo X, Li J, Zhang H, Wang Y, Shi H, Ge Y, Yu X, Wang H, Dong Y
Research in veterinary science 2022 Dec 20;152:270-276
Research in veterinary science 2022 Dec 20;152:270-276
Circadian gene CSNK1D promoted the progression of hepatocellular carcinoma by activating Wnt/β-catenin pathway via stabilizing Dishevelled Segment Polarity Protein 3.
Zhu M, Zhang J, Bian S, Zhang X, Shen Y, Ni Z, Xu S, Cheng C, Zheng W
Biological procedures online 2022 Dec 2;24(1):21
Biological procedures online 2022 Dec 2;24(1):21
Regulation of Cyclin D1 Degradation by Ubiquitin-Specific Protease 27X Is Critical for Cancer Cell Proliferation and Tumor Growth.
Alam S, Zunic A, Venkat S, Feigin ME, Atanassov BS
Molecular cancer research : MCR 2022 Dec 2;20(12):1751-1762
Molecular cancer research : MCR 2022 Dec 2;20(12):1751-1762
Polysaccharide of Atractylodes macrocephala Koidz Alleviates Cyclophosphamide-Induced Thymus Ferroptosis in Gosling.
Zhou X, Cao N, Xu D, Tian Y, Shen X, Jiang D, Huang Y, Li W, Li B
Animals : an open access journal from MDPI 2022 Dec 2;12(23)
Animals : an open access journal from MDPI 2022 Dec 2;12(23)
Evidence linking APOBEC3B genesis and evolution of innate immune antagonism by gamma-herpesvirus ribonucleotide reductases.
Moraes SN, Becker JT, Moghadasi SA, Shaban NM, Auerbach AA, Cheng AZ, Harris RS
eLife 2022 Dec 2;11
eLife 2022 Dec 2;11
Plasma exosomal miR-199a-3p downregulates cell proliferation and migration in Hirschsprung's disease by targeting mTOR.
Daiyue Y, Yang Y, Zhaorong H, Yi L, Chen W, Caiyun L, Yuqian S, Liucheng Y, Kai W
Pediatric surgery international 2022 Dec 19;39(1):54
Pediatric surgery international 2022 Dec 19;39(1):54
Decreased Expression of EZH2 in Granulosa Cells Contributes to Endometriosis-Associated Infertility by Targeting IL-1R2.
Lin X, Tong X, Zhang Y, Gu W, Huang Q, Zhang Y, Zhuo F, Zhao F, Jin X, Li C, Huang D, Zhang S, Dai Y
Endocrinology 2022 Dec 19;164(2)
Endocrinology 2022 Dec 19;164(2)
Allosteric Inhibition of c-Abl to Induce Unfolded Protein Response and Cell Death in Multiple Myeloma.
Kosako H, Yamashita Y, Morita S, Iwabuchi S, Hashimoto S, Matsuoka TA, Sonoki T, Tamura S
International journal of molecular sciences 2022 Dec 18;23(24)
International journal of molecular sciences 2022 Dec 18;23(24)
Angiogenesis-Browning Interplay Mediated by Asprosin-Knockout Contributes to Weight Loss in Mice with Obesity.
Yin T, Chen S, Zeng G, Yuan W, Lu Y, Zhang Y, Huang Q, Xiong X, Xu B, Huang Q
International journal of molecular sciences 2022 Dec 18;23(24)
International journal of molecular sciences 2022 Dec 18;23(24)
Anti-polycystic ovary syndrome effect of electroacupuncture: IMD inhibits ER stress-mediated apoptosis and autophagy in granulosa cells.
Cong J, Zhang Y, Yang X, Wang Y, He H, Wang M
Biochemical and biophysical research communications 2022 Dec 17;634:159-167
Biochemical and biophysical research communications 2022 Dec 17;634:159-167
Targeting TLR2/Rac1/cdc42/JNK Pathway to Reveal That Ruxolitinib Promotes Thrombocytopoiesis.
Yang S, Tang X, Wang L, Ni C, Wu Y, Zhou L, Zeng Y, Zhao C, Wu A, Wang Q, Xu X, Wang Y, Chen R, Zhang X, Zou L, Huang X, Wu J
International journal of molecular sciences 2022 Dec 17;23(24)
International journal of molecular sciences 2022 Dec 17;23(24)
Ivermectin Attenuates CCl(4)-Induced Liver Fibrosis in Mice by Suppressing Hepatic Stellate Cell Activation.
Ying H, Li L, Zhao Y, Ni F
International journal of molecular sciences 2022 Dec 16;23(24)
International journal of molecular sciences 2022 Dec 16;23(24)
BAF53A drives colorectal cancer development by regulating DUSP5-mediated ERK phosphorylation.
Yang Z, Huang D, Meng M, Wang W, Feng J, Fang L, Chen H, Zou S
Cell death & disease 2022 Dec 16;13(12):1049
Cell death & disease 2022 Dec 16;13(12):1049
The selective NLRP3 inflammasome inhibitor MCC950 improves isoproterenol-induced cardiac dysfunction by inhibiting cardiomyocyte senescence.
Shi Y, Zhao L, Wang J, Liu S, Zhang Y, Qin Q
European journal of pharmacology 2022 Dec 15;937:175364
European journal of pharmacology 2022 Dec 15;937:175364
EBV promotes vascular mimicry of dormant cancer cells by potentiating stemness and EMT.
Cheng T, Zhang S, Xia T, Zhang Y, Ji Y, Pan S, Xie H, Ren Q, You Y, You B
Experimental cell research 2022 Dec 15;421(2):113403
Experimental cell research 2022 Dec 15;421(2):113403
Prohibitin 1 regulates mtDNA release and downstream inflammatory responses.
Liu H, Fan H, He P, Zhuang H, Liu X, Chen M, Zhong W, Zhang Y, Zhen C, Li Y, Jiang H, Meng T, Xu Y, Zhao G, Feng D
The EMBO journal 2022 Dec 15;41(24):e111173
The EMBO journal 2022 Dec 15;41(24):e111173
BNIP3L/NIX regulates both mitophagy and pexophagy.
Wilhelm LP, Zapata-Muñoz J, Villarejo-Zori B, Pellegrin S, Freire CM, Toye AM, Boya P, Ganley IG
The EMBO journal 2022 Dec 15;41(24):e111115
The EMBO journal 2022 Dec 15;41(24):e111115
IGF2BP2-induced circRUNX1 facilitates the growth and metastasis of esophageal squamous cell carcinoma through miR-449b-5p/FOXP3 axis.
Wang C, Zhou M, Zhu P, Ju C, Sheng J, Du D, Wan J, Yin H, Xing Y, Li H, He J, He F
Journal of experimental & clinical cancer research : CR 2022 Dec 15;41(1):347
Journal of experimental & clinical cancer research : CR 2022 Dec 15;41(1):347
The traditional chinese medicine monomer Ailanthone improves the therapeutic efficacy of anti-PD-L1 in melanoma cells by targeting c-Jun.
Yu P, Wei H, Li K, Zhu S, Li J, Chen C, Zhang D, Li Y, Zhu L, Yi X, Liu N, Liu P, Zhao S, Chen X, Peng C
Journal of experimental & clinical cancer research : CR 2022 Dec 15;41(1):346
Journal of experimental & clinical cancer research : CR 2022 Dec 15;41(1):346
Regulation of Parkin in Cr (VI)-induced mitophagy in chicken hepatocytes.
Wang L, Zheng P, Cui Y, Zhang Z, Song K, Liu Y, Liu J
Ecotoxicology and environmental safety 2022 Dec 15;248:114315
Ecotoxicology and environmental safety 2022 Dec 15;248:114315
Melatonin protects oocytes from cadmium exposure-induced meiosis defects by changing epigenetic modification and enhancing mitochondrial morphology in the mouse.
Qu J, Wang Q, Niu H, Sun X, Ji D, Li Y
Ecotoxicology and environmental safety 2022 Dec 15;248:114311
Ecotoxicology and environmental safety 2022 Dec 15;248:114311
Discovery and optimization of 4-anilinoquinazoline derivatives spanning ATP binding site and allosteric site as effective EGFR-C797S inhibitors.
Dou D, Wang J, Qiao Y, Wumaier G, Sha W, Li W, Mei W, Yang T, Zhang C, He H, Wang C, Chu L, Sun B, Su R, Ma X, Gong M, Xie L, Jiang W, Diao Y, Zhu L, Zhao Z, Chen Z, Xu Y, Li S, Li H
European journal of medicinal chemistry 2022 Dec 15;244:114856
European journal of medicinal chemistry 2022 Dec 15;244:114856
Coxsackievirus Group B3 Has Oncolytic Activity against Colon Cancer through Gasdermin E-Mediated Pyroptosis.
Zhang Y, Xu T, Tian H, Wu J, Yu X, Zeng L, Liu F, Liu Q, Huang X
Cancers 2022 Dec 15;14(24)
Cancers 2022 Dec 15;14(24)
The P681H Mutation in the Spike Glycoprotein of the Alpha Variant of SARS-CoV-2 Escapes IFITM Restriction and Is Necessary for Type I Interferon Resistance.
Lista MJ, Winstone H, Wilson HD, Dyer A, Pickering S, Galao RP, De Lorenzo G, Cowton VM, Furnon W, Suarez N, Orton R, Palmarini M, Patel AH, Snell L, Nebbia G, Swanson C, Neil SJD
Journal of virology 2022 Dec 14;96(23):e0125022
Journal of virology 2022 Dec 14;96(23):e0125022
Autophagy inhibition and reactive oxygen species elimination by acetyl-CoA acetyltransferase 1 through fused in sarcoma protein to promote prostate cancer.
Guan J, Jiang X, Guo Y, Zhao W, Li J, Li Y, Cheng M, Fu L, Zhao Y, Li Q
BMC cancer 2022 Dec 14;22(1):1313
BMC cancer 2022 Dec 14;22(1):1313
NLRP6 Induces Lung Injury and Inflammation Early in Brucella and Influenza Coinfection.
Shi B, Han H, Li H, Tan L, Li X, Wang K, Li B, He W, Tian C, Yan F, Shi Y, Zheng Y, Zhao Z
Journal of personalized medicine 2022 Dec 14;12(12)
Journal of personalized medicine 2022 Dec 14;12(12)
ML216-Induced BLM Helicase Inhibition Sensitizes PCa Cells to the DNA-Crosslinking Agent Cisplatin.
Ma XY, Zhao JF, Ruan Y, Zhang WM, Zhang LQ, Cai ZD, Xu HQ
Molecules (Basel, Switzerland) 2022 Dec 12;27(24)
Molecules (Basel, Switzerland) 2022 Dec 12;27(24)
Silibinin Overcomes EMT-Driven Lung Cancer Resistance to New-Generation ALK Inhibitors.
Verdura S, Encinar JA, Teixidor E, Segura-Carretero A, Micol V, Cuyàs E, Bosch-Barrera J, Menendez JA
Cancers 2022 Dec 11;14(24)
Cancers 2022 Dec 11;14(24)
Long noncoding RNA GAS5 alleviates the inflammatory response of human periodontal ligament stem cells by regulating the NF-κB signalling pathway.
Yang Q, Liu P, Han Y, Wang C, Huang Y, Li X, Zheng Y, Li W
European journal of orthodontics 2022 Dec 1;44(6):669-678
European journal of orthodontics 2022 Dec 1;44(6):669-678
DMSO-soluble smoking particles up-regulate the vascular endothelin receptors through AMPK-SIRT1 and MAPK pathways.
Wang Y, Zhang P, Wang T, Yao D, Shi Y, Liu J, Wang B, Wei H, Liu W, Xu CB, Wang C
Chemico-biological interactions 2022 Dec 1;368:110203
Chemico-biological interactions 2022 Dec 1;368:110203
LS-007 inhibits melanoma growth via inducing apoptosis and cell cycle arrest and regulating macrophage polarization.
Yin L, Liu X, Wu J, Yang J, Wang J, Dou H, Hou Y
Melanoma research 2022 Dec 1;32(6):419-427
Melanoma research 2022 Dec 1;32(6):419-427
Novel shikonin derivatives suppress cell proliferation, migration and induce apoptosis in human triple-negative breast cancer cells via regulating PDK1/PDHC axis.
Chen Q, Han H, Lin F, Yang L, Feng L, Lai X, Wen Z, Yang M, Wang C, Ma Y, Yin T, Lu G, Lin H, Qi J, Yang Y
Life sciences 2022 Dec 1;310:121077
Life sciences 2022 Dec 1;310:121077
Aloe polymeric acemannan inhibits the cytokine storm in mouse pneumonia models by modulating macrophage metabolism.
Li L, Xu W, Luo Y, Lao C, Tong X, Du J, Huang B, Li D, Chen J, Ye H, Cong F, Guo X, Li J
Carbohydrate polymers 2022 Dec 1;297:120032
Carbohydrate polymers 2022 Dec 1;297:120032
Lentinan inhibits oxidative stress and alleviates LPS-induced inflammation and apoptosis of BMECs by activating the Nrf2 signaling pathway.
Meng M, Huo R, Wang Y, Ma N, Shi X, Shen X, Chang G
International journal of biological macromolecules 2022 Dec 1;222(Pt B):2375-2391
International journal of biological macromolecules 2022 Dec 1;222(Pt B):2375-2391
Three water soluble polysaccharides with anti-inflammatory activities from Selaginella uncinata (Desv.) Spring.
Hui H, Gao M, Zhao X, Yin L, Xu L, Li L, Peng J
International journal of biological macromolecules 2022 Dec 1;222(Pt B):1983-1995
International journal of biological macromolecules 2022 Dec 1;222(Pt B):1983-1995
Melatonin attenuates bone cancer pain via the SIRT1/HMGB1 pathway.
Yang C, Kang F, Huang X, Zhang W, Wang S, Han M, Zhang Z, Li J
Neuropharmacology 2022 Dec 1;220:109254
Neuropharmacology 2022 Dec 1;220:109254
Minocycline alleviates abnormal microglial phagocytosis of synapses in a mouse model of depression.
Han QQ, Shen SY, Chen XR, Pilot A, Liang LF, Zhang JR, Li WH, Fu Y, Le JM, Chen PQ, Yu J
Neuropharmacology 2022 Dec 1;220:109249
Neuropharmacology 2022 Dec 1;220:109249
USP1 Inhibits NF-κB/NLRP3 Induced Pyroptosis through TRAF6 in Osteoblastic MC3T3-E1 Cells.
Sun D, Peng Y, Ge S, Fu Q
Journal of musculoskeletal & neuronal interactions 2022 Dec 1;22(4):536-545
Journal of musculoskeletal & neuronal interactions 2022 Dec 1;22(4):536-545
YAP1-TEAD1 mediates the perineural invasion of prostate cancer cells induced by cancer-associated fibroblasts.
Shen T, Li Y, Wang D, Su Y, Li G, Shang Z, Niu Y, Tan X
Biochimica et biophysica acta. Molecular basis of disease 2022 Dec 1;1868(12):166540
Biochimica et biophysica acta. Molecular basis of disease 2022 Dec 1;1868(12):166540
ACAP1 Deficiency Predicts Inferior Immunotherapy Response in Solid Tumors.
Yi Q, Pu Y, Chao F, Bian P, Lv L
Cancers 2022 Dec 1;14(23)
Cancers 2022 Dec 1;14(23)
Orphan Nuclear Receptor Nur77 Mediates the Lethal Endoplasmic Reticulum Stress and Therapeutic Efficacy of Cryptomeridiol in Hepatocellular Carcinoma.
Li X, Chen Q, Liu J, Lai S, Zhang M, Zhen T, Hu H, Gao X, Wong AST, Zeng JZ
Cells 2022 Dec 1;11(23)
Cells 2022 Dec 1;11(23)
Chitosan-Gelatin-EGCG Nanoparticle-Meditated LncRNA TMEM44-AS1 Silencing to Activate the P53 Signaling Pathway for the Synergistic Reversal of 5-FU Resistance in Gastric Cancer.
Zhou M, Dong J, Huang J, Ye W, Zheng Z, Huang K, Pan Y, Cen J, Liang Y, Shu G, Ye S, Lu X, Zhang J
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2022 Aug;9(22):e2105077
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2022 Aug;9(22):e2105077
4-hydroxybenzophenone exposure inhibits mouse hippocampal neural stem cell proliferation in vitro by upregulating Cxcl1.
Lin Y, He M, Zeng X, Sheng X, Wang S, Cui F
Toxicology in vitro : an international journal published in association with BIBRA 2022 Aug;82:105367
Toxicology in vitro : an international journal published in association with BIBRA 2022 Aug;82:105367
HIIT and MICT attenuate high-fat diet-induced hepatic lipid accumulation and ER stress via the PERK-ATF4-CHOP signaling pathway.
Yuan Z, Xiao-Wei L, Juan W, Xiu-Juan L, Nian-Yun Z, Lei S
Journal of physiology and biochemistry 2022 Aug;78(3):641-652
Journal of physiology and biochemistry 2022 Aug;78(3):641-652
circNup188/miR-760-3p/Map3k8 axis regulates inflammation in cerebral ischemia.
Zhang H, Deng J, Huang K, He Y, Cai Z, He Y
Molecular and cellular probes 2022 Aug;64:101830
Molecular and cellular probes 2022 Aug;64:101830
MELK predicts poor prognosis and promotes metastasis in esophageal squamous cell carcinoma via activating the NF‑κB pathway.
Ye J, Deng W, Zhong Y, Liu H, Guo B, Qin Z, Li P, Zhong X, Wang L
International journal of oncology 2022 Aug;61(2)
International journal of oncology 2022 Aug;61(2)
High-Frequency Repetitive Transcranial Magnetic Stimulation Regulates Astrocyte Activation by Modulating the Endocannabinoid System in Parkinson's Disease.
Kang X, Zhang B, Du W, Zhao R, Liu X, Bai Y, Jiang X, Pang J, Zhao C, Mou X, Gao F, Yuan H, Sun X
Molecular neurobiology 2022 Aug;59(8):5121-5134
Molecular neurobiology 2022 Aug;59(8):5121-5134
Phosphodiesterase 4D contributes to angiotensin II-induced abdominal aortic aneurysm through smooth muscle cell apoptosis.
Gao R, Guo W, Fan T, Pang J, Hou Y, Feng X, Li B, Ge W, Fan T, Zhang T, Lu J, Jing H, Jin M, Yan C, Wang J
Experimental & molecular medicine 2022 Aug;54(8):1201-1213
Experimental & molecular medicine 2022 Aug;54(8):1201-1213
Mecheliolide elicits ROS-mediated ERS driven immunogenic cell death in hepatocellular carcinoma.
Xu Z, Xu J, Sun S, Lin W, Li Y, Lu Q, Li F, Yang Z, Lu Y, Liu W
Redox biology 2022 Aug;54:102351
Redox biology 2022 Aug;54:102351
MicroRNA-30a Targets Notch1 to Alleviate Podocyte Injury in Lupus Nephritis.
Guo A, Sun Y, Xu X, Xing Q
Immunological investigations 2022 Aug;51(6):1694-1706
Immunological investigations 2022 Aug;51(6):1694-1706
Angiotensin receptor-neprilysin inhibitor attenuates cardiac hypertrophy and improves diastolic dysfunction in a mouse model of heart failure with preserved ejection fraction.
Zhang Y, Yuan M, Suo Y, Yang Q, Shao S, Li Y, Wang Y, Bao Q, Liu T, Li G
Clinical and experimental pharmacology & physiology 2022 Aug;49(8):848-857
Clinical and experimental pharmacology & physiology 2022 Aug;49(8):848-857
Expression and role of miR-146a and SMAD4 in placental tissue of pregnant women with preeclampsia.
Qi Y, Cui S, Liu L, Liu B, Wang T, Yan S, Tian H, Huang X
The journal of obstetrics and gynaecology research 2022 Aug;48(8):2151-2161
The journal of obstetrics and gynaecology research 2022 Aug;48(8):2151-2161
Oxidative stress and Cx43-mediated apoptosis are involved in PFOS-induced nephrotoxicity.
Tang L, Yu J, Zhuge S, Chen H, Zhang L, Jiang G
Toxicology 2022 Aug;478:153283
Toxicology 2022 Aug;478:153283
EMMPRIN Promotes the Expression of MMP-9 and Exacerbates Neurological Dysfunction in a Mouse Model of Intracerebral Hemorrhage.
Liu Y, Bai Q, Yong VW, Xue M
Neurochemical research 2022 Aug;47(8):2383-2395
Neurochemical research 2022 Aug;47(8):2383-2395
The deubiquitinase USP7 regulates oxidative stress through stabilization of HO-1.
Gao M, Qi Z, Deng M, Huang H, Xu Z, Guo G, Jing J, Huang X, Xu M, Kloeber JA, Liu S, Huang J, Lou Z, Han J
Oncogene 2022 Aug;41(33):4018-4027
Oncogene 2022 Aug;41(33):4018-4027
TTC22 promotes m6A-mediated WTAP expression and colon cancer metastasis in an RPL4 binding-dependent pattern.
You A, Tian W, Yuan H, Gu L, Zhou J, Deng D
Oncogene 2022 Aug;41(32):3925-3938
Oncogene 2022 Aug;41(32):3925-3938
N(6)-methyladenosine (m(6)A) in 18S rRNA promotes fatty acid metabolism and oncogenic transformation.
Peng H, Chen B, Wei W, Guo S, Han H, Yang C, Ma J, Wang L, Peng S, Kuang M, Lin S
Nature metabolism 2022 Aug;4(8):1041-1054
Nature metabolism 2022 Aug;4(8):1041-1054
Homocysteine-Induced Disturbances in DNA Methylation Contribute to Development of Stress-Associated Cognitive Decline in Rats.
Wang SD, Wang X, Zhao Y, Xue BH, Wang XT, Chen YX, Zhang ZQ, Tian YR, Xie F, Qian LJ
Neuroscience bulletin 2022 Aug;38(8):887-900
Neuroscience bulletin 2022 Aug;38(8):887-900
MiR-19b-3p promotes tumor progression of non-small cell lung cancer via downregulating HOXA9 and predicts poor prognosis in patients.
Li ZL, Li D, Yin GQ
Histology and histopathology 2022 Aug;37(8):779-789
Histology and histopathology 2022 Aug;37(8):779-789
Phospho-proteomics identifies a critical role of ATF2 in pseudorabies virus replication.
Jiang FF, Wang RQ, Guo CY, Zheng K, Liu HL, Su L, Xie SS, Chen HC, Liu ZF
Virologica Sinica 2022 Aug;37(4):591-600
Virologica Sinica 2022 Aug;37(4):591-600
A novel natural-derived tilapia skin collagen mineralized with hydroxyapatite as a potential bone-grafting scaffold.
Yao S, Shang Y, Ren B, Deng S, Wang Z, Peng Y, Huang Z, Ma S, Peng C, Hou S
Journal of biomaterials applications 2022 Aug;37(2):219-237
Journal of biomaterials applications 2022 Aug;37(2):219-237
l-Arginine prevents 4-hydroxy-2-nonenal accumulation and depresses inflammation via inhibiting NF-κB activation.
Liang M, Wang Z, Li H, Liu B, Yang L
Journal of biochemical and molecular toxicology 2022 Aug;36(8):e23087
Journal of biochemical and molecular toxicology 2022 Aug;36(8):e23087
VEGF promotes tendon regeneration of aged rats by inhibiting adipogenic differentiation of tendon stem/progenitor cells and promoting vascularization.
Lai F, Wang J, Tang H, Huang P, Liu J, He G, Zhou M, Tao X, Tang K
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2022 Aug;36(8):e22433
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2022 Aug;36(8):e22433
Ultraviolet light induces HERV expression to activate RIG-I signalling pathway in keratinocytes.
Min X, Zheng M, Yu Y, Wu J, Kuang Q, Hu Z, Ouyang L, Lu S, Zhao M
Experimental dermatology 2022 Aug;31(8):1165-1176
Experimental dermatology 2022 Aug;31(8):1165-1176
A WWP2-PTEN-KLF5 signaling axis regulates odontoblast differentiation and dentinogenesis in mice.
Fu J, Zhang X, Zheng H, Yang G, Chen Z, Yuan G
The Journal of biological chemistry 2022 Aug;298(8):102220
The Journal of biological chemistry 2022 Aug;298(8):102220
IKBKE phosphorylates and stabilizes Snail to promote breast cancer invasion and metastasis.
Xie W, Jiang Q, Wu X, Wang L, Gao B, Sun Z, Zhang X, Bu L, Lin Y, Huang Q, Li J, Guo J
Cell death and differentiation 2022 Aug;29(8):1528-1540
Cell death and differentiation 2022 Aug;29(8):1528-1540
Brief exposure to directionally-specific pulsed electromagnetic fields stimulates extracellular vesicle release and is antagonized by streptomycin: A potential regenerative medicine and food industry paradigm.
Wong CJK, Tai YK, Yap JLY, Fong CHH, Loo LSW, Kukumberg M, Fröhlich J, Zhang S, Li JZ, Wang JW, Rufaihah AJ, Franco-Obregón A
Biomaterials 2022 Aug;287:121658
Biomaterials 2022 Aug;287:121658
Ferrostatin‑1 alleviates oxalate‑induced renal tubular epithelial cell injury, fibrosis and calcium oxalate stone formation by inhibiting ferroptosis.
Xie J, Ye Z, Li L, Xia Y, Yuan R, Ruan Y, Zhou X
Molecular medicine reports 2022 Aug;26(2)
Molecular medicine reports 2022 Aug;26(2)
MgIG exerts therapeutic effects on crizotinib-induced hepatotoxicity by limiting ROS-mediated autophagy and pyroptosis.
Li M, Wang C, Yu Z, Lan Q, Xu S, Ye Z, Li R, Ying L, Zhang X, Zhou Z
Journal of cellular and molecular medicine 2022 Aug;26(16):4492-4505
Journal of cellular and molecular medicine 2022 Aug;26(16):4492-4505
Curcumin attenuates vascular calcification via the exosomal miR-92b-3p/KLF4 axis.
Chen C, Li Y, Lu H, Liu K, Jiang W, Zhang Z, Qin X
Experimental biology and medicine (Maywood, N.J.) 2022 Aug;247(16):1420-1432
Experimental biology and medicine (Maywood, N.J.) 2022 Aug;247(16):1420-1432
N6-methyladenosine demethylase FTO regulates inflammatory cytokine secretion and tight junctions in retinal pigment epithelium cells.
Tang S, Meng J, Tan J, Liu X, Zhou H, Li N, Hou S
Clinical immunology (Orlando, Fla.) 2022 Aug;241:109080
Clinical immunology (Orlando, Fla.) 2022 Aug;241:109080
METTL3 preferentially enhances non-m(6)A translation of epigenetic factors and promotes tumourigenesis.
Wei X, Huo Y, Pi J, Gao Y, Rao S, He M, Wei Q, Song P, Chen Y, Lu D, Song W, Liang J, Xu L, Wang H, Hong G, Guo Y, Si Y, Xu J, Wang X, Ma Y, Yu S, Zou D, Jin J, Wang F, Yu J
Nature cell biology 2022 Aug;24(8):1278-1290
Nature cell biology 2022 Aug;24(8):1278-1290
Paeoniflorin-6'O-benzene sulfonate suppresses fibroblast-like synoviocytes proliferation and migration in rheumatoid arthritis through regulating GRK2-Gβγ interaction.
Zhang Y, Yang X, Han C, Wang D, Ma Y, Wei W
Experimental and therapeutic medicine 2022 Aug;24(2):523
Experimental and therapeutic medicine 2022 Aug;24(2):523
miR-29b-3p inhibits 22Rv1 prostate cancer cell proliferation through the YWHAE/BCL-2 regulatory axis.
Zhao J, Ma X, Xu H
Oncology letters 2022 Aug;24(2):289
Oncology letters 2022 Aug;24(2):289
Identification and verification of the role of crucial genes through which methionine restriction inhibits the progression of colon cancer cells.
Zhou L, Chen Z, Liu C
Oncology letters 2022 Aug;24(2):274
Oncology letters 2022 Aug;24(2):274
Nav1.6 promotes the progression of human follicular thyroid carcinoma cells via JAK-STAT signaling pathway.
Li H, Liu J, Fan N, Wang H, Thomas AM, Yan Q, Li S, Qin H
Pathology, research and practice 2022 Aug;236:153984
Pathology, research and practice 2022 Aug;236:153984
Pannexin1 inhibits autophagy of cisplatin-resistant testicular cancer cells by mediating ATP release.
Yuan M, Yao Y, Wu D, Zhu C, Dong S, Tong X
Cell cycle (Georgetown, Tex.) 2022 Aug;21(15):1651-1661
Cell cycle (Georgetown, Tex.) 2022 Aug;21(15):1651-1661
Melatonin inhibits angiotensin II-induced atrial fibrillation through preventing degradation of Ang II Type I Receptor-Associated Protein (ATRAP).
Xie X, Shen TT, Bi HL, Su ZL, Liao ZQ, Zhang Y, Shi L, Xia YL
Biochemical pharmacology 2022 Aug;202:115146
Biochemical pharmacology 2022 Aug;202:115146
Zedoarondiol inhibits atherosclerosis by regulating monocyte migration and adhesion via CXCL12/CXCR4 pathway.
Chai H, Qu H, He S, Song L, Yang Y, Huang H, Shi D
Pharmacological research 2022 Aug;182:106328
Pharmacological research 2022 Aug;182:106328
Quercetin encapsulated in folic acid-modified liposomes is therapeutic against osteosarcoma by non-covalent binding to the JH2 domain of JAK2 Via the JAK2-STAT3-PDL1.
Jing D, Wu W, Chen X, Xiao H, Zhang Z, Chen F, Zhang Z, Liu J, Shao Z, Pu F
Pharmacological research 2022 Aug;182:106287
Pharmacological research 2022 Aug;182:106287
Cullin-associated and neddylation-dissociated 1 protein (CAND1) governs cardiac hypertrophy and heart failure partially through regulating calcineurin degradation.
Li X, Zhang Y, Zhao Y, Zhou Y, Han Q, Yang Y, Zhang L, Shi L, Jin X, Zhang R, Gao H, Xue G, Li D, Zhang ZR, Lu Y, Yang B, Pan Z
Pharmacological research 2022 Aug;182:106284
Pharmacological research 2022 Aug;182:106284
TMEM41B and VMP1 modulate cellular lipid and energy metabolism for facilitating dengue virus infection.
Yousefi M, Lee WS, Yan B, Cui L, Yong CL, Yap X, Tay KSL, Qiao W, Tan D, Nurazmi NI, Linster M, Smith GJD, Lee YH, Carette JE, Ooi EE, Chan KR, Ooi YS
PLoS pathogens 2022 Aug;18(8):e1010763
PLoS pathogens 2022 Aug;18(8):e1010763
Autophagy regulates differentiation of ovarian granulosa cells through degradation of WT1.
Shao T, Ke H, Liu R, Xu L, Han S, Zhang X, Dang Y, Jiao X, Li W, Chen ZJ, Qin Y, Zhao S
Autophagy 2022 Aug;18(8):1864-1878
Autophagy 2022 Aug;18(8):1864-1878
Inhibitory activity and mechanism of silver nanoparticles against herpes simplex virus type 1.
Pan X, Zhang Y, Zhao Y, Yao S, Guan C, Wang L, Chen L
Archives of virology 2022 Aug;167(8):1619-1636
Archives of virology 2022 Aug;167(8):1619-1636
Oxyberberine, a novel HO-1 agonist, effectively ameliorates oxidative stress and inflammatory response in LPS/D-GalN induced acute liver injury mice via coactivating erythrocyte metabolism and Nrf2 signaling pathway.
Ai G, Wu X, Dou Y, Huang R, Zhong L, Liu Y, Xian Y, Lin Z, Li Y, Su Z, Chen J, Qu C
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2022 Aug;166:113215
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2022 Aug;166:113215
FXR deficiency in hepatocytes disrupts the bile acid homeostasis and inhibits autophagy to promote liver injury in Schistosoma japonicum-infected mice.
Zhang B, Li J, Zong X, Wang J, Xin L, Song H, Zhang W, Koda S, Hua H, Zhang B, Yu Q, Zheng KY, Yan C
PLoS neglected tropical diseases 2022 Aug;16(8):e0010651
PLoS neglected tropical diseases 2022 Aug;16(8):e0010651
Polyisocyanide hydrogels with tunable nonlinear elasticity mediate liver carcinoma cell functional response.
Liu Z, Fu J, Yuan H, Ma B, Cao Z, Chen Y, Xing C, Niu X, Li N, Wang H, An H
Acta biomaterialia 2022 Aug;148:152-162
Acta biomaterialia 2022 Aug;148:152-162
Hirudo verbana as a freshwater invertebrate model to assess the effects of polypropylene micro and nanoplastics dispersion in freshwater.
Baranzini N, Pulze L, Bon C, Izzo L, Pragliola S, Venditto V, Grimaldi A
Fish & shellfish immunology 2022 Aug;127:492-507
Fish & shellfish immunology 2022 Aug;127:492-507
HDAC5, negatively regulated by miR-148a-3p, promotes colon cancer cell migration.
OuYang C, Shu G, Liu J, Deng S, Lu P, Li Y, Gan Y, Xie B, Liu J, Yin G
Cancer science 2022 Aug;113(8):2560-2574
Cancer science 2022 Aug;113(8):2560-2574
Anti-proliferation and apoptosis-inducing effects of dihydroartemisinin on SH-SY5Y cells and metabolomic analysis.
Xu DL, Fan K, Zhang H, Tang LX, Wang Y, Xiang Z, Shi AM, Qu YC, Su CJ, Pan J
Translational pediatrics 2022 Aug;11(8):1346-1361
Translational pediatrics 2022 Aug;11(8):1346-1361
The surface morphology of Platycodon grandiflorus polysaccharide and its anti-apoptotic effect by targeting autophagy.
Cheng G, Zhang S, Lv M, Qi C, Fan R, Guo X, Liu J, Zhao X
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Aug;103:154212
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Aug;103:154212
Morroniside, a novel GATA3 binding molecule, inhibits hepatic stellate cells activation by enhancing lysosomal acid lipase expression.
An L, Zhang M, Lin Y, Jiang T, Xu K, Xiao S, Cai L, Kwan HY, Liu Z, Su T
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Aug;103:154199
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Aug;103:154199
The Etv1/Er81 transcription factor coordinates myelination-related genes to regulate Schwann cell differentiation and myelination.
Askar P, Xu J, Hu J, Shangguan J, Sun H, Zhou S, Yang X, Chen G, Su W, Gu Y
Annals of translational medicine 2022 Aug;10(16):875
Annals of translational medicine 2022 Aug;10(16):875
Overexpression of integrin β(2) improves migration and engraftment of adipose-derived stem cells and augments angiogenesis in myocardial infarction.
Yuan Z, Yan K, Wang J
Annals of translational medicine 2022 Aug;10(16):863
Annals of translational medicine 2022 Aug;10(16):863
Phosphorylated STYK1 restrains the inhibitory role of EGFR in autophagy initiation and EGFR-TKIs sensitivity.
Zhou C, Dong X, Wang M, Qian X, Hu M, Liang K, Liang Y, Zhang R, Huang Y, Lyu H, Xiao S, Tang Y, Ali DW, Michalak M, Chen XZ, Tang J
Cell insight 2022 Aug;1(4):100045
Cell insight 2022 Aug;1(4):100045
Deletion of Meg8-DMR Enhances Migration and Invasion of MLTC-1 Depending on the CTCF Binding Sites.
Han X, He H, Shao L, Cui S, Yu H, Zhang X, Wu Q
International journal of molecular sciences 2022 Aug 8;23(15)
International journal of molecular sciences 2022 Aug 8;23(15)
Lidocaine Inhibited Tendon Cell Proliferation and Extracellular Matrix Production by Down Regulation of Cyclin A, CDK2, Type I and Type III Collagen Expression.
Chen YC, Chang HN, Pang JS, Lin LP, Chen JM, Yu TY, Tsai WC
International journal of molecular sciences 2022 Aug 7;23(15)
International journal of molecular sciences 2022 Aug 7;23(15)
PCGF6 controls neuroectoderm specification of human pluripotent stem cells by activating SOX2 expression.
Lan X, Ding S, Zhang T, Yi Y, Li C, Jin W, Chen J, Liang K, Wang H, Jiang W
Nature communications 2022 Aug 6;13(1):4601
Nature communications 2022 Aug 6;13(1):4601
Synthesis and anticancer evaluations of novel 1H-imidazole [4,5-f][1,10] phenanthroline derivative for the treatment of colorectal cancer.
Hu S, Ma W, Wang J, Ma Y, Zhou Z, Zhang R, Du K, Zhang H, Sun M, Jiang X, Tu H, Tang X, Yao X, Chen P
European journal of pharmacology 2022 Aug 5;928:175120
European journal of pharmacology 2022 Aug 5;928:175120
The mechanism of the imbalance between proliferation and ferroptosis in pulmonary artery smooth muscle cells based on the activation of SLC7A11.
Hu P, Xu Y, Jiang Y, Huang J, Liu Y, Wang D, Tao T, Sun Z, Liu Y
European journal of pharmacology 2022 Aug 5;928:175093
European journal of pharmacology 2022 Aug 5;928:175093
Inhibition of Kruppel-like factor 7 attenuates cell proliferation and inflammation of fibroblast-like synoviocytes in rheumatoid arthritis through nuclear factor κB and mitogen-activated protein kinase signaling pathway.
Cao J, Ni Y, Zhang H, Ning X, Qi X
Experimental animals 2022 Aug 5;71(3):356-367
Experimental animals 2022 Aug 5;71(3):356-367
Design, synthesis, and in vitro protective effect evaluation of α-carboline derivatives against H(2)O(2)-induced cardiomyocyte injury.
Zhang RH, Yang D, Liao XM, Zhang H, Chen GQ, Zhang WL, Wang YC, Wang C, Liao SG, Zhou M, Wang YL, Li YJ
European journal of medicinal chemistry 2022 Aug 5;238:114469
European journal of medicinal chemistry 2022 Aug 5;238:114469
Metabolic reprogramming from glycolysis to fatty acid uptake and beta-oxidation in platinum-resistant cancer cells.
Tan Y, Li J, Zhao G, Huang KC, Cardenas H, Wang Y, Matei D, Cheng JX
Nature communications 2022 Aug 5;13(1):4554
Nature communications 2022 Aug 5;13(1):4554
Deficiency of WTAP in hepatocytes induces lipoatrophy and non-alcoholic steatohepatitis (NASH).
Li X, Ding K, Li X, Yuan B, Wang Y, Yao Z, Wang S, Huang H, Xu B, Xie L, Deng T, Chen XW, Chen Z
Nature communications 2022 Aug 4;13(1):4549
Nature communications 2022 Aug 4;13(1):4549
Myocardium-Targeted Micelle Nanomedicine That Salvages the Heart from Ischemia/Reperfusion Injury.
Yang L, Peng J, Shi A, Wang X, Li J, Su Y, Yin K, Zhao L, Zhao Y
ACS applied materials & interfaces 2022 Aug 31;14(34):38562-38574
ACS applied materials & interfaces 2022 Aug 31;14(34):38562-38574
Deep Sequencing of HPV16 E6 Region Reveals Unique Mutation Pattern of HPV16 and Predicts Cervical Cancer.
Ai W, Wu C, Jia L, Xiao X, Xu X, Ren M, Xue T, Zhou X, Wang Y, Gao C
Microbiology spectrum 2022 Aug 31;10(4):e0140122
Microbiology spectrum 2022 Aug 31;10(4):e0140122
p53 Binding Sites in Long Terminal Repeat 5Hs (LTR5Hs) of Human Endogenous Retrovirus K Family (HML-2 Subgroup) Play Important Roles in the Regulation of LTR5Hs Transcriptional Activity.
Liu M, Jia L, Li H, Liu Y, Han J, Wang X, Li T, Li J, Zhang B, Zhai X, Yu C, Li L
Microbiology spectrum 2022 Aug 31;10(4):e0048522
Microbiology spectrum 2022 Aug 31;10(4):e0048522
A high-concentrate diet provokes inflammatory responses by downregulating Forkhead box protein A2 (FOXA2) through epigenetic modifications in the liver of dairy cows.
Xie W, Xue Y, Zhang H, Wang Y, Meng M, Chang G, Shen X
Gene 2022 Aug 30;837:146703
Gene 2022 Aug 30;837:146703
S6K1 amplification confers innate resistance to CDK4/6 inhibitors through activating c-Myc pathway in patients with estrogen receptor-positive breast cancer.
Mo H, Liu X, Xue Y, Chen H, Guo S, Li Z, Wang S, Li C, Han J, Fu M, Song Y, Li D, Ma F
Molecular cancer 2022 Aug 30;21(1):171
Molecular cancer 2022 Aug 30;21(1):171
"Two-birds-one-stone" colon-targeted nanomedicine treats ulcerative colitis via remodeling immune microenvironment and anti-fibrosis.
Zhang J, Ou A, Tang X, Wang R, Fan Y, Fang Y, Zhao Y, Zhao P, Chen D, Wang B, Huang Y
Journal of nanobiotechnology 2022 Aug 30;20(1):389
Journal of nanobiotechnology 2022 Aug 30;20(1):389
IFIT3 and IFIT5 Play Potential Roles in Innate Immune Response of Porcine Pulmonary Microvascular Endothelial Cells to Highly Pathogenic Porcine Reproductive and Respiratory Syndrome Virus.
Wu Y, Song X, Cui D, Zhang T
Viruses 2022 Aug 30;14(9)
Viruses 2022 Aug 30;14(9)
The Akt Forkhead Box O Transcription Factor Axis Regulates Human Cytomegalovirus Replication.
Zhang H, Domma AJ, Goodrum FD, Moorman NJ, Kamil JP
mBio 2022 Aug 30;13(4):e0104222
mBio 2022 Aug 30;13(4):e0104222
Motoneurons innervation determines the distinct gene expressions in multinucleated myofibers.
Bai L, Tu WY, Xiao Y, Zhang K, Shen C
Cell & bioscience 2022 Aug 30;12(1):140
Cell & bioscience 2022 Aug 30;12(1):140
SETDB1 Restrains Endogenous Retrovirus Expression and Antitumor Immunity during Radiotherapy.
Pan D, Bao X, Hu M, Jiao M, Li F, Li CY
Cancer research 2022 Aug 3;82(15):2748-2760
Cancer research 2022 Aug 3;82(15):2748-2760
Perivascular and endomysial macrophages expressing VEGF and CXCL12 promote angiogenesis in anti-HMGCR immune-mediated necrotizing myopathy.
Lia A, Annese T, Fornaro M, Giannini M, D'Abbicco D, Errede M, Lorusso L, Amati A, Tampoia M, Trojano M, Virgintino D, Ribatti D, Serlenga L, Iannone F, Girolamo F
Rheumatology (Oxford, England) 2022 Aug 3;61(8):3448-3460
Rheumatology (Oxford, England) 2022 Aug 3;61(8):3448-3460
Targeting clock-controlled gene Nrf2 ameliorates inflammation-induced intervertebral disc degeneration.
Peng P, Wang D, Xu X, Wang D, Gao B, Wang H, Jia H, Shang Q, Zheng C, Gao C, Mao J, Luo Z, Yang L, Hu X
Arthritis research & therapy 2022 Aug 3;24(1):181
Arthritis research & therapy 2022 Aug 3;24(1):181
Cornuside Is a Potential Agent against Alzheimer's Disease via Orchestration of Reactive Astrocytes.
Shi JZ, Zheng XM, Zhou YF, Yun LY, Luo DM, Hao JJ, Liu PF, Zhang WK, Xu JK, Yan Y, Xie XM, He YY, Pang XB
Nutrients 2022 Aug 3;14(15)
Nutrients 2022 Aug 3;14(15)
MiR-659-3p inhibits osteosarcoma progression and metastasis by inhibiting cell proliferation and invasion via targeting SRPK1.
Gong Y, Wei ZR
BMC cancer 2022 Aug 29;22(1):934
BMC cancer 2022 Aug 29;22(1):934
Reorganization of the Landscape of Translated mRNAs in NSUN2-Deficient Cells and Specific Features of NSUN2 Target mRNAs.
Kossinova OA, Gopanenko AV, Babaylova ES, Tupikin AE, Kabilov MR, Malygin AA, Karpova GG
International journal of molecular sciences 2022 Aug 28;23(17)
International journal of molecular sciences 2022 Aug 28;23(17)
Raltitrexed regulates proliferation and apoptosis of HGC-27 cells by upregulating RSK4.
Hu C, Chen X, Lin X, Dai J, Yu J
BMC pharmacology & toxicology 2022 Aug 28;23(1):65
BMC pharmacology & toxicology 2022 Aug 28;23(1):65
Spindle and Kinetochore-associated Family Genes are Prognostic and Predictive Biomarkers in Hepatocellular Carcinoma.
Cai C, Zhang Y, Hu X, Yang S, Ye J, Wei Z, Chu T
Journal of clinical and translational hepatology 2022 Aug 28;10(4):627-641
Journal of clinical and translational hepatology 2022 Aug 28;10(4):627-641
A yeast-based system to study SARS-CoV-2 Mpro structure and to identify nirmatrelvir resistant mutations.
Ou J, Lewandowski EM, Hu Y, Lipinski AA, Morgan RT, Jacobs LMC, Zhang X, Bikowitz MJ, Langlais P, Tan H, Wang J, Chen Y, Choy JS
Research square 2022 Aug 26;
Research square 2022 Aug 26;
Discovery of a Novel Small-Molecule Inhibitor Disrupting TRBP-Dicer Interaction against Hepatocellular Carcinoma via the Modulation of microRNA Biogenesis.
Peng T, He Y, Wang T, Yu J, Ma X, Zhou Z, Sheng Y, Li L, Peng H, Li S, Zou J, Yuan Y, Zhao Y, Shi H, Li F, Liu W, Hu K, Lu X, Zhang G, Wang F
Journal of medicinal chemistry 2022 Aug 25;65(16):11010-11033
Journal of medicinal chemistry 2022 Aug 25;65(16):11010-11033
PD-1 Suppresses the Osteogenic and Odontogenic Differentiation of Stem Cells from Dental Apical Papilla via Targeting SHP2/NF-κB Axis.
Li N, Li Z, Fu L, Yan M, Wang Y, Yu J, Wu J
Stem cells (Dayton, Ohio) 2022 Aug 25;40(8):763-777
Stem cells (Dayton, Ohio) 2022 Aug 25;40(8):763-777
γ-Glutamylcysteine attenuates amyloid-β oligomers-induced neuroinflammation in microglia via blocking NF-κB signaling pathway.
Bi A, Wang Y, Chen L, Yin Z, Luo L
Chemico-biological interactions 2022 Aug 25;363:110019
Chemico-biological interactions 2022 Aug 25;363:110019
The Janus-faced role of TRPM2-S in retroperitoneal liposarcoma via increasing ROS levels.
Li X, Bu F, Ma S, Cananzi F, Zhao Y, Xiao M, Min L, Luo C
Cell communication and signaling : CCS 2022 Aug 25;20(1):128
Cell communication and signaling : CCS 2022 Aug 25;20(1):128
Ammonium tetrathiomolybdate triggers autophagy-dependent NRF2 activation in vascular endothelial cells.
Zhang M, Qiu H, Mao L, Wang B, Li N, Fan Y, Weng P, Hu S, Dong X, Qin X, Chen C, Zou Z, Yu C, Zhang J
Cell death & disease 2022 Aug 25;13(8):733
Cell death & disease 2022 Aug 25;13(8):733
Artificial Intelligence-Assisted Bioinformatics, Microneedle, and Diabetic Wound Healing: A "New Deal" of an Old Drug.
Xue Y, Chen C, Tan R, Zhang J, Fang Q, Jin R, Mi X, Sun D, Xue Y, Wang Y, Xiong R, Lu H, Tan W
ACS applied materials & interfaces 2022 Aug 24;14(33):37396-37409
ACS applied materials & interfaces 2022 Aug 24;14(33):37396-37409
Transverse endoplasmic reticulum expansion in hereditary spastic paraplegia corticospinal axons.
Zhu PP, Hung HF, Batchenkova N, Nixon-Abell J, Henderson J, Zheng P, Renvoisé B, Pang S, Xu CS, Saalfeld S, Funke J, Xie Y, Svara F, Hess HF, Blackstone C
Human molecular genetics 2022 Aug 23;31(16):2779-2795
Human molecular genetics 2022 Aug 23;31(16):2779-2795
ROS triggered local delivery of stealth exosomes to tumors for enhanced chemo/photodynamic therapy.
Wan Z, Gan X, Mei R, Du J, Fan W, Wei M, Yang G, Qin W, Zhu Z, Liu L
Journal of nanobiotechnology 2022 Aug 23;20(1):385
Journal of nanobiotechnology 2022 Aug 23;20(1):385
DNA Origami as a Nanomedicine for Targeted Rheumatoid Arthritis Therapy through Reactive Oxygen Species and Nitric Oxide Scavenging.
Ma Y, Lu Z, Jia B, Shi Y, Dong J, Jiang S, Li Z
ACS nano 2022 Aug 23;16(8):12520-12531
ACS nano 2022 Aug 23;16(8):12520-12531
HSP27 Attenuates cGAS-Mediated IFN-β Signaling through Ubiquitination of cGAS and Promotes PRV Infection.
Li X, Xie J, Li D, Li H, Niu Y, Wu B, Yang Y, Yan Z, Zhang X, Chen L, Feng R
Viruses 2022 Aug 23;14(9)
Viruses 2022 Aug 23;14(9)
The compound losartan cream inhibits scar formation via TGF-β/Smad pathway.
Zhao WY, Zhang LY, Wang ZC, Fang QQ, Wang XF, Du YZ, Shi BH, Lou D, Xuan GD, Tan WQ
Scientific reports 2022 Aug 22;12(1):14327
Scientific reports 2022 Aug 22;12(1):14327
Duodenal-jejunal bypass increases intraduodenal bile acids and upregulates duodenal SIRT1 expression in high-fat diet and streptozotocin-induced diabetic rats.
Han HF, Liu SZ, Zhang X, Wei M, Huang X, Yu WB
World journal of gastroenterology 2022 Aug 21;28(31):4338-4350
World journal of gastroenterology 2022 Aug 21;28(31):4338-4350
Neu1 deficiency increases the susceptibility of zebrafish to Edwardsiella piscicida infection via lysosomal dysfunction.
Sahashi D, Kubo Y, Ishii M, Ikeda A, Yamasaki C, Komatsu M, Shiozaki K
Gene 2022 Aug 20;836:146667
Gene 2022 Aug 20;836:146667
TP53INP2 Contributes to TGF-β2-Induced Autophagy during the Epithelial-Mesenchymal Transition in Posterior Capsular Opacification Development.
Cui Y, Yang H, Shi S, Ping X, Zheng S, Tang X, Yu X, Shentu X
Cells 2022 Aug 2;11(15)
Cells 2022 Aug 2;11(15)
Inhibition of the cardiac fibroblast-enriched histone methyltransferase Dot1L prevents cardiac fibrosis and cardiac dysfunction.
Xu J, Wang J, Long F, Zhong W, Su H, Su Z, Liu X
Cell & bioscience 2022 Aug 19;12(1):134
Cell & bioscience 2022 Aug 19;12(1):134
HLJ1 amplifies endotoxin-induced sepsis severity by promoting IL-12 heterodimerization in macrophages.
Luo WJ, Yu SL, Chang CC, Chien MH, Chang YL, Liao KM, Lin PC, Chung KP, Chuang YH, Chen JJW, Yang PC, Su KY
eLife 2022 Aug 19;11
eLife 2022 Aug 19;11
Mesenchymal stem cells protect against TBI-induced pyroptosis in vivo and in vitro through TSG-6.
Feng Z, Hua S, Li W, Han J, Li F, Chen H, Zhang Z, Xie Y, Ouyang Q, Zou X, Liu Z, Li C, Huang S, Lai Z, Cai X, Cai Y, Zou Y, Tang Y, Jiang X
Cell communication and signaling : CCS 2022 Aug 18;20(1):125
Cell communication and signaling : CCS 2022 Aug 18;20(1):125
Enhancement of BCAT2-Mediated Valine Catabolism Stimulates β-Casein Synthesis via the AMPK-mTOR Signaling Axis in Bovine Mammary Epithelial Cells.
Wang X, Xu J, Zeng H, Han Z
Journal of agricultural and food chemistry 2022 Aug 17;70(32):9898-9907
Journal of agricultural and food chemistry 2022 Aug 17;70(32):9898-9907
The LINC00623/NAT10 signaling axis promotes pancreatic cancer progression by remodeling ac4C modification of mRNA.
Feng Z, Li K, Qin K, Liang J, Shi M, Ma Y, Zhao S, Liang H, Han D, Shen B, Peng C, Chen H, Jiang L
Journal of hematology & oncology 2022 Aug 17;15(1):112
Journal of hematology & oncology 2022 Aug 17;15(1):112
Phosphorylation of GluA1-Ser831 by CaMKII Activation in the Caudate and Putamen Is Required for Behavioral Sensitization After Challenge Nicotine in Rats.
Kim S, Sohn S, Choe ES
The international journal of neuropsychopharmacology 2022 Aug 16;25(8):678-687
The international journal of neuropsychopharmacology 2022 Aug 16;25(8):678-687
Construction of a novel model based on cell-in-cell-related genes and validation of KRT7 as a biomarker for predicting survival and immune microenvironment in pancreatic cancer.
Song J, Ruze R, Chen Y, Xu R, Yin X, Wang C, Xu Q, Zhao Y
BMC cancer 2022 Aug 16;22(1):894
BMC cancer 2022 Aug 16;22(1):894
DNA damage-induced paraspeckle formation enhances DNA repair and tumor radioresistance by recruiting ribosomal protein P0.
Wang YL, Zhao WW, Bai SM, Ma Y, Yin XK, Feng LL, Zeng GD, Wang F, Feng WX, Zheng J, Wang YN, Zeng B, Liu Q, Hung MC, Wan XB
Cell death & disease 2022 Aug 16;13(8):709
Cell death & disease 2022 Aug 16;13(8):709
Salidroside ameliorates orthopedic surgery-induced cognitive dysfunction by activating adenosine 5'-monophosphate-activated protein kinase signaling in mice.
Pan CL, Dai GL, Zhang HW, Zhang CY, Meng QH, Xu L, Xu N, Zhang Y, Tan QL, Wang XL, Zhang ZY
European journal of pharmacology 2022 Aug 15;929:175148
European journal of pharmacology 2022 Aug 15;929:175148
Colchicine alleviates inflammation and improves diastolic dysfunction in heart failure rats with preserved ejection fraction.
Shen S, Duan J, Hu J, Qi Y, Kang L, Wang K, Chen J, Wu X, Xu B, Gu R
European journal of pharmacology 2022 Aug 15;929:175126
European journal of pharmacology 2022 Aug 15;929:175126
12 T high static magnetic field suppresses osteosarcoma cells proliferation by regulating intracellular ROS and iron status.
Wang S, Huyan T, Lou C, Shang P, Zhang H
Experimental cell research 2022 Aug 15;417(2):113223
Experimental cell research 2022 Aug 15;417(2):113223
CoQ10 Improves Myocardial Damage in Doxorubicin-Induced Heart Failure in C57BL/6 Mice.
Pei Z, Ma L, Li Y, Yang J, Yang Q, Yao W, Li S
Frontiers in bioscience (Landmark edition) 2022 Aug 15;27(8):244
Frontiers in bioscience (Landmark edition) 2022 Aug 15;27(8):244
Involvement of retinoic acid receptor α in the autistic-like behavior of rats with vitamin A deficiency by regulating neurexin 1 in the visual cortex: a mechanism study.
Li LS, Zhang Q, Liu H, Wu QH, Yang T, Chen J, Li TY
Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics 2022 Aug 15;24(8):928-935
Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics 2022 Aug 15;24(8):928-935
Hyperphosphorylated tau mediates neuronal death by inducing necroptosis and inflammation in Alzheimer's disease.
Dong Y, Yu H, Li X, Bian K, Zheng Y, Dai M, Feng X, Sun Y, He Y, Yu B, Zhang H, Wu J, Yu X, Wu H, Kong W
Journal of neuroinflammation 2022 Aug 15;19(1):205
Journal of neuroinflammation 2022 Aug 15;19(1):205
PAGln, an Atrial Fibrillation-Linked Gut Microbial Metabolite, Acts as a Promoter of Atrial Myocyte Injury.
Fang C, Zuo K, Jiao K, Zhu X, Fu Y, Zhong J, Xu L, Yang X
Biomolecules 2022 Aug 15;12(8)
Biomolecules 2022 Aug 15;12(8)
CD147 mediates epidermal malignant transformation through the RSK2/AP-1 pathway.
Zhang X, Guo Y, Xiao T, Li J, Guo A, Lei L, Jin C, Long Q, Su J, Yin M, Liu H, Chen C, Zhou Z, Zhu S, Tao J, Hu S, Chen X, Peng C
Journal of experimental & clinical cancer research : CR 2022 Aug 13;41(1):246
Journal of experimental & clinical cancer research : CR 2022 Aug 13;41(1):246
Intra-amniotic transplantation of brain-derived neurotrophic factor-modified mesenchymal stem cells treatment for rat fetuses with spina bifida aperta.
Ma W, Wei X, Gu H, Liu D, Luo W, Cao S, Jia S, He Y, Chen L, Bai Y, Yuan Z
Stem cell research & therapy 2022 Aug 13;13(1):413
Stem cell research & therapy 2022 Aug 13;13(1):413
Inert Pepper aptamer-mediated endogenous mRNA recognition and imaging in living cells.
Wang Q, Xiao F, Su H, Liu H, Xu J, Tang H, Qin S, Fang Z, Lu Z, Wu J, Weng X, Zhou X
Nucleic acids research 2022 Aug 12;50(14):e84
Nucleic acids research 2022 Aug 12;50(14):e84
A co-crystal berberine-ibuprofen improves obesity by inhibiting the protein kinases TBK1 and IKKɛ.
Wang M, Xu R, Liu X, Zhang L, Qiu S, Lu Y, Zhang P, Yan M, Zhu J
Communications biology 2022 Aug 12;5(1):807
Communications biology 2022 Aug 12;5(1):807
Comprehensive analysis of RNA m6A methylation in pressure overload-induced cardiac hypertrophy.
Li W, Xing C, Bao L, Han S, Luo T, Wang Z, Fan H
BMC genomics 2022 Aug 11;23(1):576
BMC genomics 2022 Aug 11;23(1):576
Hsp70 Inhibits the Replication of Fowl Adenovirus Serotype 4 by Suppressing Viral Hexon with the Assistance of DnaJC7.
Cao J, Liu S, Liu M, Wang S, Bi Z, Fan W, Shi Z, Song S, Yan L
Journal of virology 2022 Aug 10;96(15):e0080722
Journal of virology 2022 Aug 10;96(15):e0080722
DMTHB ameliorates memory impairment in Alzheimer's disease mice through regulation of neuroinflammation.
Zhang Y, Liu D, Yao X, Wen J, Wang Y, Zhang Y
Neuroscience letters 2022 Aug 10;785:136770
Neuroscience letters 2022 Aug 10;785:136770
PDE4D binds and interacts with YAP to cooperatively promote HCC progression.
Ren H, Chen Y, Ao Z, Cheng Q, Yang X, Tao H, Zhao L, Shen A, Li P, Fu Q
Cancer letters 2022 Aug 10;541:215749
Cancer letters 2022 Aug 10;541:215749
Jianpi Huayu decoction inhibits the epithelial-mesenchymal transition of hepatocellular carcinoma cells by suppressing exosomal miR-23a-3p/Smad signaling.
Xie CF, Feng KL, Wang JN, Luo R, Fang CK, Zhang Y, Shen CP, Zhong C
Journal of ethnopharmacology 2022 Aug 10;294:115360
Journal of ethnopharmacology 2022 Aug 10;294:115360
Penthorum chinense Pursh. extract attenuates non-alcholic fatty liver disease by regulating gut microbiota and bile acid metabolism in mice.
Li X, Zhao W, Xiao M, Yu L, Chen Q, Hu X, Zhao Y, Xiong L, Chen X, Wang X, Ba Y, Guo Q, Wu X
Journal of ethnopharmacology 2022 Aug 10;294:115333
Journal of ethnopharmacology 2022 Aug 10;294:115333
Covalent Organic Framework (COF): A Drug and Carrier to Attenuate Retinal Ganglion Cells Death in an Acute Glaucoma Mouse Model.
Yao K, Liang X, Zhang G, Rong Y, Zhang Q, Liao Q, Zhang H, Xi K, Wang J
Polymers 2022 Aug 10;14(16)
Polymers 2022 Aug 10;14(16)
MAB21L1 promotes survival of lens epithelial cells through control of αB-crystallin and ATR/CHK1/p53 pathway.
Xiao Y, Xiang JW, Gao Q, Bai YY, Huang ZX, Hu XH, Wang L, Li DW
Aging 2022 Aug 10;14(15):6128-6148
Aging 2022 Aug 10;14(15):6128-6148
PREX1 depletion ameliorates high-fat diet-induced non-alcoholic fatty liver disease in mice and mitigates palmitic acid-induced hepatocellular injury via suppressing the NF-κB signaling pathway.
Li Z, Wu K, Zou Y, Gong W, Wang P, Wang H
Toxicology and applied pharmacology 2022 Aug 1;448:116074
Toxicology and applied pharmacology 2022 Aug 1;448:116074
Lysosome docking to WIPI1 rings and ER-connected phagophores occurs during DNAJB12- and GABARAP-dependent selective autophagy of misfolded P23H-rhodopsin.
Kennedy A, Ren HY, Madden VJ, Cyr DM
Molecular biology of the cell 2022 Aug 1;33(9):ar84
Molecular biology of the cell 2022 Aug 1;33(9):ar84
Regulatory roles of fibronectin and integrin α5 in reorganization of the actin cytoskeleton and completion of adipogenesis.
Uetaki M, Onishi N, Oki Y, Shimizu T, Sugihara E, Sampetrean O, Watanabe T, Yanagi H, Suda K, Fujii H, Kano K, Saya H, Nobusue H
Molecular biology of the cell 2022 Aug 1;33(9):ar78
Molecular biology of the cell 2022 Aug 1;33(9):ar78
Polycystin-2 (PC2) is a key determinant of in vitro myogenesis.
Márquez-Nogueras KM, Vuchkovska V, DiNello E, Osorio-Valencia S, Kuo IY
American journal of physiology. Cell physiology 2022 Aug 1;323(2):C333-C346
American journal of physiology. Cell physiology 2022 Aug 1;323(2):C333-C346
Cinnamaldehyde protects against ligature-induced periodontitis through the inhibition of microbial accumulation and inflammatory responses of host immune cells.
Ou Y, Yan M, Gao G, Wang W, Lu Q, Chen J
Food & function 2022 Aug 1;13(15):8091-8106
Food & function 2022 Aug 1;13(15):8091-8106
Shen Shuai Ⅱ Recipe attenuates renal fibrosis in chronic kidney disease by improving hypoxia-induced the imbalance of mitochondrial dynamics via PGC-1α activation.
Wang M, Wang L, Zhou Y, Feng X, Ye C, Wang C
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Apr;98:153947
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Apr;98:153947
Urolithin A attenuates arsenic-induced gut barrier dysfunction.
Ghosh S, Banerjee M, Haribabu B, Jala VR
Archives of toxicology 2022 Apr;96(4):987-1007
Archives of toxicology 2022 Apr;96(4):987-1007
HTR1A Inhibits the Progression of Triple-Negative Breast Cancer via TGF-β Canonical and Noncanonical Pathways.
Liu Q, Sun H, Liu Y, Li X, Xu B, Li L, Jin W
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2022 Apr;9(12):e2105672
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2022 Apr;9(12):e2105672
Elevated RAP1A expression correlates with the severity of acute GVHD after umbilical cord blood transplantation.
Wang S, Wang D, Chang Y, Geng L, Qiang P, Sun G, Tang B, Zhao X, Zhou Z, Liu H
Transplant immunology 2022 Apr;71:101546
Transplant immunology 2022 Apr;71:101546
Basic fibroblast growth factor inhibits aortic valvular interstitial cells calcification via Notch1 pathway.
Gao Y, Li N, Xue Q, Fan X, Liu X, Han L
Journal of investigative medicine : the official publication of the American Federation for Clinical Research 2022 Apr;70(4):907-913
Journal of investigative medicine : the official publication of the American Federation for Clinical Research 2022 Apr;70(4):907-913
Generation of a heterozygous SCN5A knockout human induced pluripotent stem cell line by CRISPR/Cas9 edition.
Gizon M, Duboscq-Bidot L, El Kassar L, Bobin P, Ader F, Giraud-Triboult K, Charron P, Villard E, Fontaine V, Neyroud N
Stem cell research 2022 Apr;60:102680
Stem cell research 2022 Apr;60:102680
LncRNA HOTAIR promotes proliferation and suppresses apoptosis of mouse spermatogonium GC-1 cells by sponging miR-761 to modulate NANOS2 expression.
Kong X, Fei Q, Pan C, Jin J, Zheng J, Wu D, Li H, Huang X
In vitro cellular & developmental biology. Animal 2022 Apr;58(4):295-306
In vitro cellular & developmental biology. Animal 2022 Apr;58(4):295-306
Grem1 accelerates nucleus pulposus cell apoptosis and intervertebral disc degeneration by inhibiting TGF-β-mediated Smad2/3 phosphorylation.
Chen S, Lei L, Li Z, Chen F, Huang Y, Jiang G, Guo X, Zhao Z, Liu H, Wang H, Liu C, Zheng Z, Wang J
Experimental & molecular medicine 2022 Apr;54(4):518-530
Experimental & molecular medicine 2022 Apr;54(4):518-530
High expression of NPM1 via the Wnt/β-catenin signalling pathway might predict poor prognosis for patients with prostate adenocarcinoma.
Ruan Y, Xu H, Ji X
Clinical and experimental pharmacology & physiology 2022 Apr;49(4):525-535
Clinical and experimental pharmacology & physiology 2022 Apr;49(4):525-535
Autophagy modulation in resveratrol protective effects on steroidogenesis in high-fat diet-fed mice and H(2)O(2)-challenged TM3 cells.
Wang P, Lin M, Chen C, Lv ZM
Molecular biology reports 2022 Apr;49(4):2973-2983
Molecular biology reports 2022 Apr;49(4):2973-2983
Midkine promotes breast cancer cell proliferation and migration by upregulating NR3C1 expression and activating the NF-κB pathway.
Zhang L, Song L, Xu Y, Xu Y, Zheng M, Zhang P, Wang Q
Molecular biology reports 2022 Apr;49(4):2953-2961
Molecular biology reports 2022 Apr;49(4):2953-2961
Trichostatin A inhibits dendritic cell maturation through down-regulating NF-κ B (p65) pathway.
Yu Y, Liu B, Chen S, Wang J, Chen F, Liu T, Jiang N, Chen W, Weng S, Cai X, Xiang D
Molecular biology reports 2022 Apr;49(4):2619-2627
Molecular biology reports 2022 Apr;49(4):2619-2627
Metformin inhibits pulmonary artery smooth muscle cell proliferation by upregulating p21 via NONRATT015587.2.
Sun Z, Liu Y, Hu R, Wang T, Li Y, Liu N
International journal of molecular medicine 2022 Apr;49(4)
International journal of molecular medicine 2022 Apr;49(4)
Alda-1, an Aldehyde Dehydrogenase 2 Agonist, Improves Cutaneous Wound Healing by Activating Epidermal Keratinocytes via Akt/GSK-3β/β-Catenin Pathway.
Zhang SM, Yang Z, Qi FZ
Aesthetic plastic surgery 2022 Apr;46(Suppl 1):126-127
Aesthetic plastic surgery 2022 Apr;46(Suppl 1):126-127
Atractylenolide II inhibits tumor-associated macrophages (TAMs)-induced lung cancer cell metastasis.
Zhang Y, Liu Y, Wang J, Jiang Z, Zhang L, Cui Y, Zhao D, Wang Y
Immunopharmacology and immunotoxicology 2022 Apr;44(2):227-237
Immunopharmacology and immunotoxicology 2022 Apr;44(2):227-237
Baicalin inhibits inflammation of lipopolysaccharide-induced acute lung injury toll like receptor-4/myeloid differentiation primary response 88/nuclear factor-kappa B signaling pathway.
Changle Z, Cuiling F, Feng F, Xiaoqin Y, Guishu W, Liangtian S, Jiakun Z
Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan 2022 Apr;42(2):200-212
Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan 2022 Apr;42(2):200-212
Downregulation of FAPP2 gene induces cell autophagy and inhibits PI3K/AKT/mTOR pathway in T-cell acute lymphoblastic leukemia.
Yuan T, Wang J, Shi C, Wang Y, Xia B, Xu W, Yang H, Yang Y, Ye MT, Khalid S, Liang Y, Tian C, You MJ, Wang Y
Hematological oncology 2022 Apr;40(2):249-257
Hematological oncology 2022 Apr;40(2):249-257
Interleukin-17A mediates tobacco smoke-induced lung cancer epithelial-mesenchymal transition through transcriptional regulation of ΔNp63α on miR-19.
Xie C, Zhu J, Huang C, Yang X, Wang X, Meng Y, Geng S, Wu J, Shen H, Hu Z, Meng Z, Li X, Zhong C
Cell biology and toxicology 2022 Apr;38(2):273-289
Cell biology and toxicology 2022 Apr;38(2):273-289
Effects of bone marrow-derived mesenchymal stem cells on doxorubicin-induced liver injury in rats.
Celik Samanci T, Gökcimen A, Kilic Eren M, Gürses KM, Pilevneli H, Kuyucu Y
Journal of biochemical and molecular toxicology 2022 Apr;36(4):e22985
Journal of biochemical and molecular toxicology 2022 Apr;36(4):e22985
The fungal Clitocybe nebularis lectin binds distinct cell surface glycoprotein receptors to induce cell death selectively in Jurkat cells.
Perišić Nanut M, Žurga S, Konjar Š, Prunk M, Kos J, Sabotič J
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2022 Apr;36(4):e22215
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2022 Apr;36(4):e22215
Enzyme-instructed self-assembly of peptide-drug conjugates in tear fluids for ocular drug delivery.
Hu Y, Wang Y, Deng J, Ding X, Lin D, Shi H, Chen L, Lin D, Wang Y, Vakal S, Wang J, Li X
Journal of controlled release : official journal of the Controlled Release Society 2022 Apr;344:261-271
Journal of controlled release : official journal of the Controlled Release Society 2022 Apr;344:261-271
EGFR signaling promotes nuclear translocation of plasma membrane protein TSPAN8 to enhance tumor progression via STAT3-mediated transcription.
Lu X, An L, Fan G, Zang L, Huang W, Li J, Liu J, Ge W, Huang Y, Xu J, Du S, Cao Y, Zhou T, Yin H, Yu L, Jiao S, Wang H
Cell research 2022 Apr;32(4):359-374
Cell research 2022 Apr;32(4):359-374
Angiogenic factor AGGF1 blocks neointimal formation after vascular injury via interaction with integrin α7 on vascular smooth muscle cells.
Yu Y, Li Y, Peng H, Song Q, Da X, Li H, He Z, Ren X, Xu C, Yao Y, Wang QK
The Journal of biological chemistry 2022 Apr;298(4):101759
The Journal of biological chemistry 2022 Apr;298(4):101759
CircPAPPA Regulates the Proliferation, Migration, Invasion, Apoptosis, and Cell Cycle of Trophoblast Cells Through the miR-3127-5p/HOXA7 Axis.
Li J, Han J, Zhao A, Zhang G
Reproductive sciences (Thousand Oaks, Calif.) 2022 Apr;29(4):1215-1225
Reproductive sciences (Thousand Oaks, Calif.) 2022 Apr;29(4):1215-1225
LncRNA SNHG16 promotes colorectal cancer cell proliferation, migration, and epithelial-mesenchymal transition through miR-124-3p/MCP-1.
Chen ZY, Wang XY, Yang YM, Wu MH, Yang L, Jiang DT, Cai H, Peng Y
Gene therapy 2022 Apr;29(3-4):193-205
Gene therapy 2022 Apr;29(3-4):193-205
FAK regulates cardiomyocyte mitochondrial fission and function through Drp1.
Chang YW, Song ZH, Chen CC
The FEBS journal 2022 Apr;289(7):1897-1910
The FEBS journal 2022 Apr;289(7):1897-1910
The tyrosine phosphatase PTPN14 inhibits the activation of STAT3 in PEDV infected Vero cells.
Huang H, Li Y, Li D, Wang L, Jiao W, Bai Y, Zhang G
Veterinary microbiology 2022 Apr;267:109391
Veterinary microbiology 2022 Apr;267:109391
Inhibition of RUNX1 blocks the differentiation of lung fibroblasts to myofibroblasts.
Dubey S, Dubey PK, Umeshappa CS, Ghebre YT, Krishnamurthy P
Journal of cellular physiology 2022 Apr;237(4):2169-2182
Journal of cellular physiology 2022 Apr;237(4):2169-2182
The plasma membrane H(+) -ATPase FgPMA1 regulates the development, pathogenicity, and phenamacril sensitivity of Fusarium graminearum by interacting with FgMyo-5 and FgBmh2.
Wu L, Yuan Z, Wang P, Mao X, Zhou M, Hou Y
Molecular plant pathology 2022 Apr;23(4):489-502
Molecular plant pathology 2022 Apr;23(4):489-502
Tumor-promoting mechanisms of macrophage-derived extracellular vesicles-enclosed microRNA-660 in breast cancer progression.
Li C, Li R, Hu X, Zhou G, Jiang G
Breast cancer research and treatment 2022 Apr;192(2):353-368
Breast cancer research and treatment 2022 Apr;192(2):353-368
Deubiquitinase-targeting chimeras for targeted protein stabilization.
Henning NJ, Boike L, Spradlin JN, Ward CC, Liu G, Zhang E, Belcher BP, Brittain SM, Hesse MJ, Dovala D, McGregor LM, Valdez Misiolek R, Plasschaert LW, Rowlands DJ, Wang F, Frank AO, Fuller D, Estes AR, Randal KL, Panidapu A, McKenna JM, Tallarico JA, Schirle M, Nomura DK
Nature chemical biology 2022 Apr;18(4):412-421
Nature chemical biology 2022 Apr;18(4):412-421
Phytohormone abscisic acid ameliorates neuropathic pain via regulating LANCL2 protein abundance and glial activation at the spinal cord.
Maixner DW, Christy D, Kong L, Viatchenko-Karpinski V, Horner KA, Hooks SB, Weng HR
Molecular pain 2022 Apr;18:17448069221107781
Molecular pain 2022 Apr;18:17448069221107781
Inhibition of DNA methylation de-represses peroxisome proliferator-activated receptor-γ and attenuates pulmonary fibrosis.
Wei A, Gao Q, Chen F, Zhu X, Chen X, Zhang L, Su X, Dai J, Shi Y, Cao W
British journal of pharmacology 2022 Apr;179(7):1304-1318
British journal of pharmacology 2022 Apr;179(7):1304-1318
Aberrant epigenetic regulation of RARβ by TET2 is involved in cutaneous squamous cell carcinoma resistance to retinoic acid.
Zhang X, Cong Y, Chu Z, Shi L, Zheng Y, Zhao Q, Geng S, Guo K
The international journal of biochemistry & cell biology 2022 Apr;145:106190
The international journal of biochemistry & cell biology 2022 Apr;145:106190
EZH2 Inhibitor Enhances the STING Agonist‒Induced Antitumor Immunity in Melanoma.
Xu T, Dai J, Tang L, Yang L, Si L, Sheng X, Cui C, Chi Z, Kong Y, Guo J
The Journal of investigative dermatology 2022 Apr;142(4):1158-1170.e8
The Journal of investigative dermatology 2022 Apr;142(4):1158-1170.e8
Kruppel like factor 16 promotes lung adenocarcinoma progression by upregulating lamin B2.
Jiao X, Gao W, Ren H, Wu Y, Li T, Li S, Yan H
Bioengineered 2022 Apr;13(4):9482-9494
Bioengineered 2022 Apr;13(4):9482-9494
CircMCTP2 (has-circ-0000658) facilitates the proliferation and metastasis of bladder carcinoma through modulating the miR-498/murine double minute-2 axis.
Gu Q, Hou W, Shi L, Zhu Z, Liu H, He X
Bioengineered 2022 Apr;13(4):10734-10748
Bioengineered 2022 Apr;13(4):10734-10748
CircMYC promotes proliferation, migration, invasion and inhibits apoptosis of small cell lung cancer by targeting miR-145/ Matrix Metallopeptidase 2 axis.
Yang X, Tao L, Xu Y, Li S, Yang W, Wang L, Zhu J
Bioengineered 2022 Apr;13(4):10552-10563
Bioengineered 2022 Apr;13(4):10552-10563
Cigarette smoke-induced oxidative stress activates NRF2 to mediate fibronectin disorganization in vascular formation.
Xue J, Liao Q, Luo M, Hua C, Zhao J, Yu G, Chen X, Li X, Zhang X, Ran R, Lu F, Wang Y, Qiao L
Open biology 2022 Apr;12(4):210310
Open biology 2022 Apr;12(4):210310
Galectin-3 promotes calcification of human aortic valve interstitial cells via the NF-kappa B signaling pathway.
Luo J, Wang S, Liu X, Zheng Q, Wang Z, Huang Y, Shi J
Cardiovascular diagnosis and therapy 2022 Apr;12(2):196-207
Cardiovascular diagnosis and therapy 2022 Apr;12(2):196-207
ECSIT inhibits cell death to increase tumor progression and metastasis via p53 in human breast cancer.
Hu Y, Liu W, Zhang X, Liu D
Translational cancer research 2022 Apr;11(4):699-709
Translational cancer research 2022 Apr;11(4):699-709
Study of novel NARS2 variants in patient of combined oxidative phosphorylation deficiency 24.
Zhang Y, Zhao X, Xu Y, Chen L, Li N, Yao R, Wang X, Wang J, Yu T
Translational pediatrics 2022 Apr;11(4):448-457
Translational pediatrics 2022 Apr;11(4):448-457
LncRNA GAS5 regulates migration and epithelial-to-mesenchymal transition in lens epithelial cells via the miR-204-3p/TGFBR1 axis.
Li X, Sun M, Cheng A, Zheng G
Laboratory investigation; a journal of technical methods and pathology 2022 Apr;102(4):452-460
Laboratory investigation; a journal of technical methods and pathology 2022 Apr;102(4):452-460
Downregulated ALKBH5 contributes to myocardial ischemia/reperfusion injury by increasing m(6)A modification of Trio mRNA.
Li J, Chen J, Zhao M, Li Z, Liu N, Fang H, Fang M, Zhu P, Lei L, Chen C
Annals of translational medicine 2022 Apr;10(7):417
Annals of translational medicine 2022 Apr;10(7):417
A hierarchical bilayer architecture for complex tissue regeneration.
Yu M, Luo D, Qiao J, Guo J, He D, Jin S, Tang L, Wang Y, Shi X, Mao J, Cui S, Fu Y, Li Z, Liu D, Zhang T, Zhang C, Li Z, Zhou Y, Liu Y
Bioactive materials 2022 Apr;10:93-106
Bioactive materials 2022 Apr;10:93-106
Drug-peptide supramolecular hydrogel boosting transcorneal permeability and pharmacological activity via ligand-receptor interaction.
Chen L, Deng J, Yu A, Hu Y, Jin B, Du P, Zhou J, Lei L, Wang Y, Vakal S, Li X
Bioactive materials 2022 Apr;10:420-429
Bioactive materials 2022 Apr;10:420-429
Low-metastatic melanoma cells acquire enhanced metastatic capability via exosomal transfer of miR-199a-1-5p from highly metastatic melanoma cells.
Zhao Q, Chen H, Li X, Zeng B, Sun Z, Liu D, Chen Y, Zhang Y, Rosie Xing H, Wang J
Cell death discovery 2022 Apr 9;8(1):188
Cell death discovery 2022 Apr 9;8(1):188
The m6A demethylase ALKBH5 promotes tumor progression by inhibiting RIG-I expression and interferon alpha production through the IKKε/TBK1/IRF3 pathway in head and neck squamous cell carcinoma.
Jin S, Li M, Chang H, Wang R, Zhang Z, Zhang J, He Y, Ma H
Molecular cancer 2022 Apr 9;21(1):97
Molecular cancer 2022 Apr 9;21(1):97
USP26 promotes anaplastic thyroid cancer progression by stabilizing TAZ.
Tang J, Luo Y, Xiao L
Cell death & disease 2022 Apr 9;13(4):326
Cell death & disease 2022 Apr 9;13(4):326
Elevated FAM84B promotes cell proliferation via interacting with NPM1 in esophageal squamous cell carcinoma.
Wang F, Cheng C, Wang X, Chen F, Li H, Zhou Y, Wang Y, Hu X, Kong P, Zhang L, Cheng X, Cui Y
Cell death discovery 2022 Apr 8;8(1):182
Cell death discovery 2022 Apr 8;8(1):182
Mechanosensitive Piezo1 channels mediate renal fibrosis.
Zhao X, Kong Y, Liang B, Xu J, Lin Y, Zhou N, Li J, Jiang B, Cheng J, Li C, Wang W
JCI insight 2022 Apr 8;7(7)
JCI insight 2022 Apr 8;7(7)
Aldehyde dehydrogenase 2 and PARP1 interaction modulates hepatic HDL biogenesis by LXRα-mediated ABCA1 expression.
Li L, Zhong S, Li R, Liang N, Zhang L, Xia S, Xu X, Chen X, Chen S, Tao Y, Yin H
JCI insight 2022 Apr 8;7(7)
JCI insight 2022 Apr 8;7(7)
Transportin-3 Facilitates Uncoating of Influenza A Virus.
Zou J, Yu L, Zhu Y, Yang S, Zhao J, Zhao Y, Jiang M, Xie S, Liu H, Zhao C, Zhou H
International journal of molecular sciences 2022 Apr 8;23(8)
International journal of molecular sciences 2022 Apr 8;23(8)
Mechanism exploration of ancient pharmaceutic processing (Paozhi) improving the gastroprotective efficacy of Aucklandiae Radix.
Song S, Qiu R, Jin X, Zhou Z, Yan J, Ou Q, Liu X, Li W, Mao Y, Yao W, Lu T
Journal of ethnopharmacology 2022 Apr 6;287:114911
Journal of ethnopharmacology 2022 Apr 6;287:114911
SIX5-activated LINC01468 promotes lung adenocarcinoma progression by recruiting SERBP1 to regulate SERPINE1 mRNA stability and recruiting USP5 to facilitate PAI1 protein deubiquitylation.
Yuan Y, Zhou D, Chen F, Yang Z, Gu W, Zhang K
Cell death & disease 2022 Apr 6;13(4):312
Cell death & disease 2022 Apr 6;13(4):312
DELE1 tracks perturbed protein import and processing in human mitochondria.
Fessler E, Krumwiede L, Jae LT
Nature communications 2022 Apr 6;13(1):1853
Nature communications 2022 Apr 6;13(1):1853
PT109, a novel multi-kinase inhibitor suppresses glioblastoma multiforme through cell reprogramming: Involvement of PTBP1/PKM1/2 pathway.
Yang Y, Tu Y, Lu J, Chen Q, Zhu Z, Peng W, Zhu W, Wen S, Zhang J, Yin W, Pi R
European journal of pharmacology 2022 Apr 5;920:174837
European journal of pharmacology 2022 Apr 5;920:174837
GSK-3β-mediated activation of NLRP3 inflammasome leads to pyroptosis and apoptosis of rat cardiomyocytes and fibroblasts.
Wang SH, Cui LG, Su XL, Komal S, Ni RC, Zang MX, Zhang LR, Han SN
European journal of pharmacology 2022 Apr 5;920:174830
European journal of pharmacology 2022 Apr 5;920:174830
Pdcd4 promotes lipid deposition by attenuating PPARα-mediated fatty acid oxidation in hepatocytes.
Du X, Osoro EK, Chen Q, Yan X, Gao D, Wu L, Ren J, Feng L, Wu N, Lu K, Yang X, Zhong B, Han Y, Zhang F, Li D, Lan X, Lu S
Molecular and cellular endocrinology 2022 Apr 5;545:111562
Molecular and cellular endocrinology 2022 Apr 5;545:111562
Augmin-dependent microtubule self-organization drives kinetochore fiber maturation in mammals.
Almeida AC, Soares-de-Oliveira J, Drpic D, Cheeseman LP, Damas J, Lewin HA, Larkin DM, Aguiar P, Pereira AJ, Maiato H
Cell reports 2022 Apr 5;39(1):110610
Cell reports 2022 Apr 5;39(1):110610
KLF5 inhibition overcomes oxaliplatin resistance in patient-derived colorectal cancer organoids by restoring apoptotic response.
Shen X, Zhang Y, Xu Z, Gao H, Feng W, Li W, Miao Y, Xu Z, Zong Y, Zhao J, Lu A
Cell death & disease 2022 Apr 5;13(4):303
Cell death & disease 2022 Apr 5;13(4):303
Rhoifolin from Plumula Nelumbinis exhibits anti-cancer effects in pancreatic cancer via AKT/JNK signaling pathways.
Zheng B, Zheng Y, Zhang N, Zhang Y, Zheng B
Scientific reports 2022 Apr 5;12(1):5654
Scientific reports 2022 Apr 5;12(1):5654
FMNL2 suppresses cell migration and invasion of breast cancer: a reduction of cytoplasmic p27 via RhoA/LIMK/Cofilin pathway.
Jiao X, Wang B, Yang L, Zhao Q, Zhang M, Liu X, Zhou C, Wang R, Chen H, Wang J, Ren Y, Liu P
Cell death discovery 2022 Apr 4;8(1):155
Cell death discovery 2022 Apr 4;8(1):155
TGF-β-induced CCR8 promoted macrophage transdifferentiation into myofibroblast-like cells.
Liu H, Guan Q, Zhao P, Li J
Experimental lung research 2022 Apr 4;:1-14
Experimental lung research 2022 Apr 4;:1-14
Dexamethasone induces ferroptosis via P53/SLC7A11/GPX4 pathway in glucocorticoid-induced osteonecrosis of the femoral head.
Sun F, Zhou JL, Liu ZL, Jiang ZW, Peng H
Biochemical and biophysical research communications 2022 Apr 30;602:149-155
Biochemical and biophysical research communications 2022 Apr 30;602:149-155
Baclofen attenuates cognitive deficits in post-cardiac arrest brain injury.
Sun Y, Cong T, Li L, Li J, Wu H, Chen X, Zhou Y, Xiao Z
Biochemical and biophysical research communications 2022 Apr 30;602:135-141
Biochemical and biophysical research communications 2022 Apr 30;602:135-141
Cdh1 Deficiency Sensitizes TNBC Cells to PARP Inhibitors.
Li J, Lan M, Peng J, Xiong Q, Xu Y, Yang Y, Zhou Y, Liu J, Zeng Z, Yang X, Zhang Z, Zhang P, Zhu Q, Wu W
Genes 2022 Apr 30;13(5)
Genes 2022 Apr 30;13(5)
3,3'-Diindolylmethane Enhances Fluorouracil Sensitivity via Inhibition of Pyrimidine Metabolism in Colorectal Cancer.
Zhang J, Zou S, Zhang Y, Yang Z, Wang W, Meng M, Feng J, Zhang P, Xiao L, Lee MH, Fang L
Metabolites 2022 Apr 30;12(5)
Metabolites 2022 Apr 30;12(5)
Asymmetric Pericentrosomal CD133 Endosomes Induce the Unequal Autophagic Activity During Cytokinesis in CD133-Positive Human Neuroblastoma Cells.
Izumi H, Li Y, Yasunami M, Sato S, Mae T, Kaneko Y, Nakagawara A
Stem cells (Dayton, Ohio) 2022 Apr 29;40(4):371-384
Stem cells (Dayton, Ohio) 2022 Apr 29;40(4):371-384
HOXC6 impacts epithelial-mesenchymal transition and the immune microenvironment through gene transcription in gliomas.
Huang H, Huo Z, Jiao J, Ji W, Huang J, Bian Z, Xu B, Shao J, Sun J
Cancer cell international 2022 Apr 29;22(1):170
Cancer cell international 2022 Apr 29;22(1):170
Trappc9 Deficiency Impairs the Plasticity of Stem Cells.
Usman M, Li Y, Ke Y, Chhetri G, Islam MA, Wang Z, Li X
International journal of molecular sciences 2022 Apr 28;23(9)
International journal of molecular sciences 2022 Apr 28;23(9)
Map of Enteropathogenic Escherichia coli Targets Mitochondria and Triggers DRP-1-Mediated Mitochondrial Fission and Cell Apoptosis in Bovine Mastitis.
Li Y, Zhu Y, Chu B, Liu N, Chen S, Wang J, Zou Y
International journal of molecular sciences 2022 Apr 28;23(9)
International journal of molecular sciences 2022 Apr 28;23(9)
Grape-Seed-Derived Procyanidin Attenuates Chemotherapy-Induced Cognitive Impairment by Suppressing MMP-9 Activity and Related Blood-Brain-Barrier Damage.
Song C, Gao C, Wang Z
Brain sciences 2022 Apr 28;12(5)
Brain sciences 2022 Apr 28;12(5)
KRT17 Promotes the Activation of HSCs via EMT in Liver Fibrosis.
Chen J, Ge SJ, Feng HJ, Wu SZ, Ji R, Huang WR, Huang W, Lu CH
Journal of clinical and translational hepatology 2022 Apr 28;10(2):207-218
Journal of clinical and translational hepatology 2022 Apr 28;10(2):207-218
Ferrous Bisglycinate Supplementation Modulates Intestinal Antioxidant Capacity via the AMPK/FOXO Pathway and Reconstitutes Gut Microbiota and Bile Acid Profiles in Pigs.
Dong Z, Zhang D, Wu X, Yin Y, Wan D
Journal of agricultural and food chemistry 2022 Apr 27;70(16):4942-4951
Journal of agricultural and food chemistry 2022 Apr 27;70(16):4942-4951
High altitude is associated with pTau deposition, neuroinflammation, and myelin loss.
Iacono D, Murphy EK, Sherman PM, Chapapas H, Cerqueira B, Christensen C, Perl DP, Sladky J
Scientific reports 2022 Apr 27;12(1):6839
Scientific reports 2022 Apr 27;12(1):6839
MiR-145 modulates the radiosensitivity of non-small cell lung cancer cells by suppression of TMOD3.
Li H, Zhao S, Chen X, Feng G, Chen Z, Fan S
Carcinogenesis 2022 Apr 25;43(3):288-296
Carcinogenesis 2022 Apr 25;43(3):288-296
Trans-cinnamaldehyde protects against phenylephrine-induced cardiomyocyte hypertrophy through the CaMKII/ERK pathway.
Qian D, Tian J, Wang S, Shan X, Zhao P, Chen H, Xu M, Guo W, Zhang C, Lu R
BMC complementary medicine and therapies 2022 Apr 25;22(1):115
BMC complementary medicine and therapies 2022 Apr 25;22(1):115
Engineered Cas12a-Plus nuclease enables gene editing with enhanced activity and specificity.
Huang H, Huang G, Tan Z, Hu Y, Shan L, Zhou J, Zhang X, Ma S, Lv W, Huang T, Liu Y, Wang D, Zhao X, Lin Y, Rong Z
BMC biology 2022 Apr 25;20(1):91
BMC biology 2022 Apr 25;20(1):91
TMT-based proteomics analysis of the cerebral cortex of TauT knockout rats.
Xia Y, Huang X, Mo L, Wang C, Fan W, Huang H
Proteome science 2022 Apr 25;20(1):6
Proteome science 2022 Apr 25;20(1):6
Ageing related thyroid deficiency increases brain-targeted transport of liver-derived ApoE4-laden exosomes leading to cognitive impairment.
Zhang M, Gong W, Zhang D, Ji M, Chen B, Chen B, Li X, Zhou Y, Dong C, Wen G, Zhan X, Wu X, Cui L, Feng Y, Wang S, Yuan H, Xu E, Xia M, Verkhratsky A, Li B
Cell death & disease 2022 Apr 25;13(4):406
Cell death & disease 2022 Apr 25;13(4):406
The organic cation transporter 2 regulates dopamine D1 receptor signaling at the Golgi apparatus.
Puri NM, Romano GR, Lin TY, Mai QN, Irannejad R
eLife 2022 Apr 25;11
eLife 2022 Apr 25;11
Mechanical Load and Piezo1 Channel Regulated Myosin II Activity in Mouse Lenses.
Allen A, Maddala R, Eldawy C, Rao PV
International journal of molecular sciences 2022 Apr 24;23(9)
International journal of molecular sciences 2022 Apr 24;23(9)
Exercise activates autophagy and regulates endoplasmic reticulum stress in muscle of high-fat diet mice to alleviate insulin resistance.
Cheng F, Dun Y, Cheng J, Ripley-Gonzalez JW, Jiang W, You B, Liu S
Biochemical and biophysical research communications 2022 Apr 23;601:45-51
Biochemical and biophysical research communications 2022 Apr 23;601:45-51
GALNT8 suppresses breast cancer cell metastasis potential by regulating EGFR O-GalNAcylation.
Huang T, Meng F, Huang H, Wang L, Wang L, Liu Y, Liu Y, Wang J, Li W, Zhang J, Liu Y
Biochemical and biophysical research communications 2022 Apr 23;601:16-23
Biochemical and biophysical research communications 2022 Apr 23;601:16-23
Targeting DRD2 by the antipsychotic drug, penfluridol, retards growth of renal cell carcinoma via inducing stemness inhibition and autophagy-mediated apoptosis.
Tung MC, Lin YW, Lee WJ, Wen YC, Liu YC, Chen JQ, Hsiao M, Yang YC, Chien MH
Cell death & disease 2022 Apr 23;13(4):400
Cell death & disease 2022 Apr 23;13(4):400
Ziprasidone Induces Rabbit Atrium Arrhythmogenesis via Modification of Oxidative Stress and Sodium/Calcium Homeostasis.
Tai BY, Lu MK, Yang HY, Tsai CS, Lin CY
Biomedicines 2022 Apr 23;10(5)
Biomedicines 2022 Apr 23;10(5)
p97/UBXD1 Generate Ubiquitylated Proteins That Are Sequestered into Nuclear Envelope Herniations in Torsin-Deficient Cells.
Prophet SM, Naughton BS, Schlieker C
International journal of molecular sciences 2022 Apr 21;23(9)
International journal of molecular sciences 2022 Apr 21;23(9)
[Identification of microRNAs targeting vitamin D receptor and their effect on parathyroid hormone secretion in secondary hyperparathyroidism].
Jiang H, Li P, Liu L, Huang S, Li J, Wu W
Nan fang yi ke da xue xue bao = Journal of Southern Medical University 2022 Apr 20;42(4):509-517
Nan fang yi ke da xue xue bao = Journal of Southern Medical University 2022 Apr 20;42(4):509-517
Exosomal miR-146a-5p and miR-155-5p promote CXCL12/CXCR7-induced metastasis of colorectal cancer by crosstalk with cancer-associated fibroblasts.
Wang D, Wang X, Song Y, Si M, Sun Y, Liu X, Cui S, Qu X, Yu X
Cell death & disease 2022 Apr 20;13(4):380
Cell death & disease 2022 Apr 20;13(4):380
Suppression of premature transcription termination leads to reduced mRNA isoform diversity and neurodegeneration.
LaForce GR, Farr JS, Liu J, Akesson C, Gumus E, Pinkard O, Miranda HC, Johnson K, Sweet TJ, Ji P, Lin A, Coller J, Philippidou P, Wagner EJ, Schaffer AE
Neuron 2022 Apr 20;110(8):1340-1357.e7
Neuron 2022 Apr 20;110(8):1340-1357.e7
Predict the role of lncRNA in kidney aging based on RNA sequencing.
Li J, Gao F, Wei L, Chen L, Qu N, Zeng L, Luo Y, Huang X, Jiang H
BMC genomics 2022 Apr 2;23(1):254
BMC genomics 2022 Apr 2;23(1):254
Tanshinone I attenuates fibrosis in fibrotic kidneys through down-regulation of inhibin beta-A.
Wu M, Yang F, Huang D, Ye C
BMC complementary medicine and therapies 2022 Apr 19;22(1):110
BMC complementary medicine and therapies 2022 Apr 19;22(1):110
Regulatory variants at 2q33.1 confer schizophrenia risk by modulating distal gene TYW5 expression.
Li S, Li J, Liu J, Wang J, Li X, Huo Y, Li Y, Liu Y, Li M, Xiao X, Luo XJ
Brain : a journal of neurology 2022 Apr 18;145(2):770-786
Brain : a journal of neurology 2022 Apr 18;145(2):770-786
Pcsk6 Deficiency Promotes Cardiomyocyte Senescence by Modulating Ddit3-Mediated ER Stress.
Zhan W, Chen L, Liu H, Long C, Liu J, Ding S, Wu Q, Chen S
Genes 2022 Apr 18;13(4)
Genes 2022 Apr 18;13(4)
Loss of serine/threonine protein kinase 25 in retinal ganglion cells ameliorates high glucose-elicited damage through regulation of the AKT-GSK-3β/Nrf2 pathway.
Zhou Z, Li H, Bai S, Xu Z, Jiao Y
Biochemical and biophysical research communications 2022 Apr 16;600:87-93
Biochemical and biophysical research communications 2022 Apr 16;600:87-93
Paeonol protects against acute pancreatitis by inhibiting M1 macrophage polarization via the NLRP3 inflammasomes pathway.
Yuan C, Xu X, Wang N, Zhu Q, Zhang J, Gong W, Ding Y, Xiao W, Chen W, Lu G, Yao G, Pan J, Wu K
Biochemical and biophysical research communications 2022 Apr 16;600:35-43
Biochemical and biophysical research communications 2022 Apr 16;600:35-43
Caveolae promote successful abscission by controlling intercellular bridge tension during cytokinesis.
Andrade V, Bai J, Gupta-Rossi N, Jimenez AJ, Delevoye C, Lamaze C, Echard A
Science advances 2022 Apr 15;8(15):eabm5095
Science advances 2022 Apr 15;8(15):eabm5095
Human umbilical cord mesenchymal stem cell-derived exosomal microRNA-148a-3p inhibits neointimal hyperplasia by targeting Serpine1.
Zhang X, Zhou Y, Ye Y, Wu R, Li W, Yao C, Wang S
Archives of biochemistry and biophysics 2022 Apr 15;719:109155
Archives of biochemistry and biophysics 2022 Apr 15;719:109155
ELAV-like RNA binding protein 1 regulates osteogenesis in diabetic osteoporosis: Involvement of divalent metal transporter 1.
Ren Y, Yang M, Wang X, Xu B, Xu Z, Su B
Molecular and cellular endocrinology 2022 Apr 15;546:111559
Molecular and cellular endocrinology 2022 Apr 15;546:111559
GDAP2 Overexpression Affects the Development of Neurons and Dysregulates Neuronal Excitatory Synaptic Transmission.
Hu D, Guo Y, Wu M, Ma Y, Jing W
Neuroscience 2022 Apr 15;488:32-43
Neuroscience 2022 Apr 15;488:32-43
Cytochalasin Q exerts anti-melanoma effect by inhibiting creatine kinase B.
Lu Y, Zhang P, Chen H, Tong Q, Wang J, Li Q, Tian C, Yang J, Li S, Zhang Z, Yuan H, Xiang M
Toxicology and applied pharmacology 2022 Apr 15;441:115971
Toxicology and applied pharmacology 2022 Apr 15;441:115971
Silencing of Nudix type 5 represses proliferation and invasion and enhances chemosensitivity of gastric carcinoma cells by affecting the AKT/GSK-3β/β-catenin pathway.
Tan D, Zhang Y
Toxicology and applied pharmacology 2022 Apr 15;441:115968
Toxicology and applied pharmacology 2022 Apr 15;441:115968
ILF3 represses repeat-derived microRNAs targeting RIG-I mediated type I interferon response.
Chen G, Yang Y, Wu QJ, Cao L, Ruan W, Shao C, Jiang L, Tang P, Ma S, Jiang A, Wang Z, Wu K, Zhang QC, Fu XD, Zhou Y
Journal of molecular biology 2022 Apr 15;434(7):167469
Journal of molecular biology 2022 Apr 15;434(7):167469
Linkage of methionine addiction, histone lysine hypermethylation, and malignancy.
Yamamoto J, Inubushi S, Han Q, Tashiro Y, Sugisawa N, Hamada K, Aoki Y, Miyake K, Matsuyama R, Bouvet M, Clarke SG, Endo I, Hoffman RM
iScience 2022 Apr 15;25(4):104162
iScience 2022 Apr 15;25(4):104162
New Cases of Hypochromic Microcytic Anemia Due to Mutations in the SLC11A2 Gene and Functional Characterization of the G75R Mutation.
Romero-Cortadellas L, Hernández G, Ferrer-Cortès X, Zalba-Jadraque L, Fuster JL, Bermúdez-Cortés M, Galera-Miñarro AM, Pérez-Montero S, Tornador C, Sánchez M
International journal of molecular sciences 2022 Apr 15;23(8)
International journal of molecular sciences 2022 Apr 15;23(8)
Substrate stiffness regulates differentiation of induced pluripotent stem cells into heart valve endothelial cells.
Cao H, Zhou Q, Liu C, Zhang Y, Xie M, Qiao W, Dong N
Acta biomaterialia 2022 Apr 15;143:115-126
Acta biomaterialia 2022 Apr 15;143:115-126
EGFR/MET promotes hepatocellular carcinoma metastasis by stabilizing tumor cells and resisting to RTKs inhibitors in circulating tumor microemboli.
Song S, Yu Z, You Y, Liu C, Xie X, Lv H, Xiao F, Zhu Q, Qin C
Cell death & disease 2022 Apr 15;13(4):351
Cell death & disease 2022 Apr 15;13(4):351
SNORD1C maintains stemness and 5-FU resistance by activation of Wnt signaling pathway in colorectal cancer.
Liu Y, Zhao C, Wang G, Chen J, Ju S, Huang J, Wang X
Cell death discovery 2022 Apr 14;8(1):200
Cell death discovery 2022 Apr 14;8(1):200
The dynamic alteration of transcriptional regulation by crucial TFs during tumorigenesis of gastric cancer.
Yu B, Dai W, Pang L, Sang Q, Li F, Yu J, Feng H, Li J, Hou J, Yan C, Su L, Zhu Z, Li YY, Liu B
Molecular medicine (Cambridge, Mass.) 2022 Apr 14;28(1):41
Molecular medicine (Cambridge, Mass.) 2022 Apr 14;28(1):41
Selective sorting and secretion of hY4 RNA fragments into extracellular vesicles mediated by methylated YBX1 to promote lung cancer progression.
Li C, Wang W, Sun Y, Ni Y, Qin F, Li X, Wang T, Guo M, Sun G
Journal of experimental & clinical cancer research : CR 2022 Apr 11;41(1):136
Journal of experimental & clinical cancer research : CR 2022 Apr 11;41(1):136
Benzo(a)pyrene induces airway epithelial injury through Wnt5a-mediated non-canonical Wnt-YAP/TAZ signaling.
Fan L, Li W, Ma J, Cheng M, Xie L, Ye Z, Xie Y, Wang B, Yu L, Zhou Y, Chen W
The Science of the total environment 2022 Apr 1;815:151965
The Science of the total environment 2022 Apr 1;815:151965
Microcystin-leucine arginine (MC-LR) induces mouse ovarian inflammation by promoting granulosa cells to produce inflammatory cytokine via activation of cGAS-STING signaling.
Liu K, Zhao X, Guo M, Zhu J, Li D, Ding J, Han X, Wu J
Toxicology letters 2022 Apr 1;358:6-16
Toxicology letters 2022 Apr 1;358:6-16
Antiviral Effects of ABMA and DABMA against Influenza Virus In Vitro and In Vivo via Regulating the Endolysosomal Pathway and Autophagy.
Liu H, Jiang C, Wu Y, Wu M, Wu J, Zhao G, Sun J, Huang X, Li J, Sheng R, Barbier J, Cintrat JC, Gillet D, Su W
International journal of molecular sciences 2022 Apr 1;23(7)
International journal of molecular sciences 2022 Apr 1;23(7)
Systematic Survey of the Regulatory Networks of the Long Noncoding RNA BANCR in Cervical Cancer Cells.
Wang B, Wang M, Jia S, Li T, Yang M, Ge F
Journal of proteome research 2022 Apr 1;21(4):1137-1152
Journal of proteome research 2022 Apr 1;21(4):1137-1152
Platelet-derived microvesicles regulate vascular smooth muscle cell energy metabolism via PRKAA after intimal injury.
Yan J, Fan YJ, Bao H, Li YG, Zhang SM, Yao QP, Huo YL, Jiang ZL, Qi YX, Han Y
Journal of cell science 2022 Apr 1;135(7)
Journal of cell science 2022 Apr 1;135(7)
Sec13 promotes oligodendrocyte differentiation and myelin repair through autocrine pleiotrophin signaling.
Liu Z, Yan M, Lei W, Jiang R, Dai W, Chen J, Wang C, Li L, Wu M, Nian X, Li D, Sun D, Lv X, Wang C, Xie C, Yao L, Wu C, Hu J, Xiao N, Mo W, Wang Z, Zhang L
The Journal of clinical investigation 2022 Apr 1;132(7)
The Journal of clinical investigation 2022 Apr 1;132(7)
miR-142a-3p Enhances FlaA N/C Protection Against Radiation-Mediated Intestinal Injury by Modulating the IRAK1/NF-κB Signaling Pathway.
Liu T, Wu DM, Zhang F, Zhang T, He M, Zhao YY, Li J, Li L, Xu Y
International journal of radiation oncology, biology, physics 2022 Apr 1;112(5):1256-1268
International journal of radiation oncology, biology, physics 2022 Apr 1;112(5):1256-1268
A novel role for apatinib in enhancing radiosensitivity in non-small cell lung cancer cells by suppressing the AKT and ERK pathways.
Li L, Li Y, Zou H
PeerJ 2021;9:e12356
PeerJ 2021;9:e12356
Identification and validation of candidate genes dysregulated in alveolar macrophages of acute respiratory distress syndrome.
Mao Y, Lv X, Xu W, Ying Y, Qin Z, Liao H, Chen L, Liu Y
PeerJ 2021;9:e12312
PeerJ 2021;9:e12312
N-acetyl-L-tryptophan attenuates hepatic ischemia-reperfusion injury via regulating TLR4/NLRP3 signaling pathway in rats.
Pan Y, Yu S, Wang J, Li W, Li H, Bai C, Sheng Y, Li M, Wang C, Liu J, Xie P, Wang C, Jiang J, Li J
PeerJ 2021;9:e11909
PeerJ 2021;9:e11909
Involvement of plasminogen activator inhibitor-1 and its related molecules in atrial fibrosis in patients with atrial fibrillation.
Li Q, Lai Y, Gao X, Li X, Deng CY, Guo H, Zhao J, Yang H, Xu Y, Wu S, Xue Y, Rao F
PeerJ 2021;9:e11488
PeerJ 2021;9:e11488
Identification of potential genes in upper tract urothelial carcinoma using next-generation sequencing with bioinformatics and in vitro analyses.
Lee HY, Li CC, Li WM, Hsu YL, Yeh HC, Ke HL, Yeh BW, Huang CN, Li CF, Kuo PL, Wu WJ
PeerJ 2021;9:e11343
PeerJ 2021;9:e11343
Melatonin ameliorates myocardial injury by reducing apoptosis and autophagy of cardiomyocytes in a rat cardiopulmonary bypass model.
Huang X, Hou J, Huang S, Feng K, Yue Y, Li H, Huang S, Liang M, Chen G, Wu Z
PeerJ 2021;9:e11264
PeerJ 2021;9:e11264
Long non-coding RNA taurine upregulated gene 1 is downregulated in osteoporosis and influences the osteogenic differentiation of bone marrow mesenchymal stem cells.
Teng Z, Zhu Y, Hao Q, Yu X, Teng Y, Yue Q, Zhang X, Lu S
PeerJ 2021;9:e11251
PeerJ 2021;9:e11251
Screening and identification of endometrial proteins as novel potential biomarkers for repeated implantation failure.
Wang C, Feng Y, Zhou WJ, Cheng ZJ, Jiang MY, Zhou Y, Fei XY
PeerJ 2021;9:e11009
PeerJ 2021;9:e11009
Human Umbilical Cord Mesenchymal Stem Cells Improve Locomotor Function in Parkinson's Disease Mouse Model Through Regulating Intestinal Microorganisms.
Sun Z, Gu P, Xu H, Zhao W, Zhou Y, Zhou L, Zhang Z, Wang W, Han R, Chai X, An S
Frontiers in cell and developmental biology 2021;9:808905
Frontiers in cell and developmental biology 2021;9:808905
TMAO-Activated Hepatocyte-Derived Exosomes Impair Angiogenesis via Repressing CXCR4.
Liu X, Shao Y, Tu J, Sun J, Dong B, Wang Z, Zhou J, Chen L, Tao J, Chen J
Frontiers in cell and developmental biology 2021;9:804049
Frontiers in cell and developmental biology 2021;9:804049
p53-Induced LINC00893 Regulates RBFOX2 Stability to Suppress Gastric Cancer Progression.
Ou X, Zhou X, Li J, Ye J, Liu H, Fang D, Cai Q, Cai S, He Y, Xu J
Frontiers in cell and developmental biology 2021;9:796451
Frontiers in cell and developmental biology 2021;9:796451
SCG2 is a Prognostic Biomarker Associated With Immune Infiltration and Macrophage Polarization in Colorectal Cancer.
Wang H, Yin J, Hong Y, Ren A, Wang H, Li M, Zhao Q, Jiang C, Liu L
Frontiers in cell and developmental biology 2021;9:795133
Frontiers in cell and developmental biology 2021;9:795133
Midkine Prevents Calcification of Aortic Valve Interstitial Cells via Intercellular Crosstalk.
Zhou Q, Cao H, Hang X, Liang H, Zhu M, Fan Y, Shi J, Dong N, He X
Frontiers in cell and developmental biology 2021;9:794058
Frontiers in cell and developmental biology 2021;9:794058
Harmine Alleviated Sepsis-Induced Cardiac Dysfunction by Modulating Macrophage Polarization via the STAT/MAPK/NF-κB Pathway.
Ruan W, Ji X, Qin Y, Zhang X, Wan X, Zhu C, Lv C, Hu C, Zhou J, Lu L, Guo X
Frontiers in cell and developmental biology 2021;9:792257
Frontiers in cell and developmental biology 2021;9:792257
m6A Modification-Mediated DUXAP8 Regulation of Malignant Phenotype and Chemotherapy Resistance of Hepatocellular Carcinoma Through miR-584-5p/MAPK1/ERK Pathway Axis.
Liu Z, Lu J, Fang H, Sheng J, Cui M, Yang Y, Tang B, Zhang X
Frontiers in cell and developmental biology 2021;9:783385
Frontiers in cell and developmental biology 2021;9:783385
Keratin 17 Is Required for Lipid Metabolism in Keratinocytes and Benefits Epidermal Permeability Barrier Homeostasis.
Pang B, Zhu Z, Xiao C, Luo Y, Fang H, Bai Y, Sun Z, Ma J, Dang E, Wang G
Frontiers in cell and developmental biology 2021;9:779257
Frontiers in cell and developmental biology 2021;9:779257
OPA1 Modulates Mitochondrial Ca(2+) Uptake Through ER-Mitochondria Coupling.
Cartes-Saavedra B, Macuada J, Lagos D, Arancibia D, Andrés ME, Yu-Wai-Man P, Hajnóczky G, Eisner V
Frontiers in cell and developmental biology 2021;9:774108
Frontiers in cell and developmental biology 2021;9:774108
Curdione and Schisandrin C Synergistically Reverse Hepatic Fibrosis via Modulating the TGF-β Pathway and Inhibiting Oxidative Stress.
Dai W, Qin Q, Li Z, Lin L, Li R, Fang Z, Han Y, Mu W, Ren L, Liu T, Zhan X, Xiao X, Bai Z
Frontiers in cell and developmental biology 2021;9:763864
Frontiers in cell and developmental biology 2021;9:763864
Oncogenic Activation of YAP Signaling Sensitizes Ferroptosis of Hepatocellular Carcinoma via ALOXE3-Mediated Lipid Peroxidation Accumulation.
Qin Y, Pei Z, Feng Z, Lin P, Wang S, Li Y, Huo F, Wang Q, Wang Z, Chen ZN, Wu J, Wang YF
Frontiers in cell and developmental biology 2021;9:751593
Frontiers in cell and developmental biology 2021;9:751593
IL-18-Mediated SLC7A5 Overexpression Enhances Osteogenic Differentiation of Human Bone Marrow Mesenchymal Stem Cells via the c-MYC Pathway.
Ni F, Zhang T, Xiao W, Dong H, Gao J, Liu Y, Li J
Frontiers in cell and developmental biology 2021;9:748831
Frontiers in cell and developmental biology 2021;9:748831
PPARγ/SOD2 Protects Against Mitochondrial ROS-Dependent Apoptosis via Inhibiting ATG4D-Mediated Mitophagy to Promote Pancreatic Cancer Proliferation.
Nie S, Shi Z, Shi M, Li H, Qian X, Peng C, Ding X, Zhang S, Lv Y, Wang L, Kong B, Zou X, Shen S
Frontiers in cell and developmental biology 2021;9:745554
Frontiers in cell and developmental biology 2021;9:745554
Platelet-Derived Microvesicles Promote VSMC Dedifferentiation After Intimal Injury via Src/Lamtor1/mTORC1 Signaling.
Liu JT, Bao H, Fan YJ, Li ZT, Yao QP, Han Y, Zhang ML, Jiang ZL, Qi YX
Frontiers in cell and developmental biology 2021;9:744320
Frontiers in cell and developmental biology 2021;9:744320
An Advanced Systems Pharmacology Strategy Reveals AKR1B1, MMP2, PTGER3 as Key Genes in the Competing Endogenous RNA Network of Compound Kushen Injection Treating Gastric Carcinoma by Integrated Bioinformatics and Experimental Verification.
Zhou W, Wu C, Zhao C, Huang Z, Lu S, Fan X, Tan Y, Stalin A, You R, Liu X, Zhang J, Wu Z, Wu J
Frontiers in cell and developmental biology 2021;9:742421
Frontiers in cell and developmental biology 2021;9:742421
Reducing Inflammation and Vascular Invasion in Intervertebral Disc Degeneration via Cystathionine-γ-Lyase Inhibitory Effect on E-Selectin.
Xu H, Wei K, Tu J, Chen Y, He Y, Ding Y, Xu H, Bao X, Xie H, Fang H, Wang H
Frontiers in cell and developmental biology 2021;9:741046
Frontiers in cell and developmental biology 2021;9:741046
PBX1 Attenuates Hair Follicle-Derived Mesenchymal Stem Cell Senescence and Apoptosis by Alleviating Reactive Oxygen Species-Mediated DNA Damage Instead of Enhancing DNA Damage Repair.
Wang Y, Sui Y, Lian A, Han X, Liu F, Zuo K, Liu M, Sun W, Wang Z, Liu Z, Zou F, Lu R, Jin M, Du H, Xu K, Liu X, Liu J
Frontiers in cell and developmental biology 2021;9:739868
Frontiers in cell and developmental biology 2021;9:739868
PINK1 Alleviates Cognitive Impairments via Attenuating Pathological Tau Aggregation in a Mouse Model of Tauopathy.
Jiang XJ, Wu YQ, Ma R, Chang YM, Li LL, Zhu JH, Liu GP, Li G
Frontiers in cell and developmental biology 2021;9:736267
Frontiers in cell and developmental biology 2021;9:736267
Increased Nuclear Transporter Importin 7 Contributes to the Tumor Growth and Correlates With CD8 T Cell Infiltration in Cervical Cancer.
Chen J, Hu Y, Teng Y, Yang B
Frontiers in cell and developmental biology 2021;9:732786
Frontiers in cell and developmental biology 2021;9:732786
LncRNA RNA Component of Mitochondrial RNA-Processing Endoribonuclease Promotes AKT-Dependent Breast Cancer Growth and Migration by Trapping MicroRNA-206.
Huang Y, Xie B, Cao M, Lu H, Wu X, Hao Q, Zhou X
Frontiers in cell and developmental biology 2021;9:730538
Frontiers in cell and developmental biology 2021;9:730538
PRDM16 Inhibits Cell Proliferation and Migration via Epithelial-to-Mesenchymal Transition by Directly Targeting Pyruvate Carboxylase in Papillary Thyroid Cancer.
Liu WL, Guan Q, Wen D, Ma B, Xu WB, Hu JQ, Wei WJ, Li DS, Wang Y, Xiang J, Liao T, Ji QH
Frontiers in cell and developmental biology 2021;9:723777
Frontiers in cell and developmental biology 2021;9:723777
Macrophage-Mediated Bone Formation in Scaffolds Modified With MSC-Derived Extracellular Matrix Is Dependent on the Migration Inhibitory Factor Signaling Pathway.
Deng M, Tan J, Dai Q, Luo F, Xu J
Frontiers in cell and developmental biology 2021;9:714011
Frontiers in cell and developmental biology 2021;9:714011
Depletion of Demethylase KDM6 Enhances Early Neuroectoderm Commitment of Human PSCs.
Meng Y, Zhang T, Zheng R, Ding S, Yang J, Liu R, Jiang Y, Jiang W
Frontiers in cell and developmental biology 2021;9:702462
Frontiers in cell and developmental biology 2021;9:702462
Design, Synthesis, and Biological Evaluation of Pyrano[2,3-c]-pyrazole-Based RalA Inhibitors Against Hepatocellular Carcinoma.
Wang Y, He M, Li X, Chai J, Jiang Q, Peng C, He G, Huang W
Frontiers in chemistry 2021;9:700956
Frontiers in chemistry 2021;9:700956
Cardiac Overexpression of XIN Prevents Dilated Cardiomyopathy Caused by TNNT2 ΔK210 Mutation.
Li B, Guo Y, Zhan Y, Zhou X, Li Y, Zhao C, Sun N, Xu C, Liang Q
Frontiers in cell and developmental biology 2021;9:691749
Frontiers in cell and developmental biology 2021;9:691749
LncRNA CRNDE Promotes ATG4B-Mediated Autophagy and Alleviates the Sensitivity of Sorafenib in Hepatocellular Carcinoma Cells.
Chen L, Sun L, Dai X, Li T, Yan X, Zhang Y, Xiao H, Shen X, Huang G, Xiang W, Zhang Y, Tan D, Yang S, Nie Y, Huang X, Lian J, He F
Frontiers in cell and developmental biology 2021;9:687524
Frontiers in cell and developmental biology 2021;9:687524
GDF11 Alleviates Pathological Myocardial Remodeling in Diabetic Cardiomyopathy Through SIRT1-Dependent Regulation of Oxidative Stress and Apoptosis.
Zhu HZ, Zhang LY, Zhai ME, Xia L, Cao Y, Xu L, Li KF, Jiang LQ, Shi H, Li X, Zhou YN, Ding W, Wang DX, Gao EH, Liu JC, Yu SQ, Duan WX
Frontiers in cell and developmental biology 2021;9:686848
Frontiers in cell and developmental biology 2021;9:686848
SUN5 Interacting With Nesprin3 Plays an Essential Role in Sperm Head-to-Tail Linkage: Research on Sun5 Gene Knockout Mice.
Zhang Y, Yang L, Huang L, Liu G, Nie X, Zhang X, Xing X
Frontiers in cell and developmental biology 2021;9:684826
Frontiers in cell and developmental biology 2021;9:684826
Autophagy-Related LC3 Accumulation Interacted Directly With LIR Containing RIPK1 and RIPK3, Stimulating Necroptosis in Hypoxic Cardiomyocytes.
Huang Y, Feng Y, Cui L, Yang L, Zhang Q, Zhang J, Jiang X, Zhang X, Lv Y, Jia JZ, Zhang DX, Huang YS
Frontiers in cell and developmental biology 2021;9:679637
Frontiers in cell and developmental biology 2021;9:679637
Quiescin Sulfhydryl Oxidase 2 Overexpression Predicts Poor Prognosis and Tumor Progression in Patients With Colorectal Cancer: A Study Based on Data Mining and Clinical Verification.
Jiang T, Zheng L, Li X, Liu J, Song H, Xu Y, Dong C, Liu L, Wang H, Wang S, Wang R, Song J
Frontiers in cell and developmental biology 2021;9:678770
Frontiers in cell and developmental biology 2021;9:678770
NudC L279P Mutation Destabilizes Filamin A by Inhibiting the Hsp90 Chaperoning Pathway and Suppresses Cell Migration.
Liu M, Xu Z, Zhang C, Yang C, Feng J, Lu Y, Zhang W, Chen W, Xu X, Sun X, Yang M, Liu W, Zhou T, Yang Y
Frontiers in cell and developmental biology 2021;9:671233
Frontiers in cell and developmental biology 2021;9:671233
Exosomal miR-2276-5p in Plasma Is a Potential Diagnostic and Prognostic Biomarker in Glioma.
Sun J, Sun Z, Gareev I, Yan T, Chen X, Ahmad A, Zhang D, Zhao B, Beylerli O, Yang G, Zhao S
Frontiers in cell and developmental biology 2021;9:671202
Frontiers in cell and developmental biology 2021;9:671202
Comprehensive Analysis of the Transcriptome-Wide m6A Methylome in Pterygium by MeRIP Sequencing.
Jiang Y, Zhang X, Zhang X, Zhao K, Zhang J, Yang C, Chen Y
Frontiers in cell and developmental biology 2021;9:670528
Frontiers in cell and developmental biology 2021;9:670528
α-Enolase Lies Downstream of mTOR/HIF1α and Promotes Thyroid Carcinoma Progression by Regulating CST1.
Liu Y, Liao L, An C, Wang X, Li Z, Xu Z, Liu J, Liu S
Frontiers in cell and developmental biology 2021;9:670019
Frontiers in cell and developmental biology 2021;9:670019
Force-Induced Autophagy in Periodontal Ligament Stem Cells Modulates M1 Macrophage Polarization via AKT Signaling.
Jiang N, He D, Ma Y, Su J, Wu X, Cui S, Li Z, Zhou Y, Yu H, Liu Y
Frontiers in cell and developmental biology 2021;9:666631
Frontiers in cell and developmental biology 2021;9:666631
SP1-Mediated Upregulation of Long Noncoding RNA ZFAS1 Involved in Non-syndromic Cleft Lip and Palate via Inactivating WNT/β-Catenin Signaling Pathway.
Chen S, Jia Z, Cai M, Ye M, Wu D, Wan T, Zhang B, Wu P, Xu Y, Guo Y, Tian C, Ma D, Ma J
Frontiers in cell and developmental biology 2021;9:662780
Frontiers in cell and developmental biology 2021;9:662780
NLGN3 Upregulates Expression of ADAM10 to Promote the Cleavage of NLGN3 via Activating the LYN Pathway in Human Gliomas.
Dang NN, Li XB, Zhang M, Han C, Fan XY, Huang SH
Frontiers in cell and developmental biology 2021;9:662763
Frontiers in cell and developmental biology 2021;9:662763
The E3 Ligase PIAS1 Regulates p53 Sumoylation to Control Stress-Induced Apoptosis of Lens Epithelial Cells Through the Proapoptotic Regulator Bax.
Nie Q, Chen H, Zou M, Wang L, Hou M, Xiang JW, Luo Z, Gong XD, Fu JL, Wang Y, Zheng SY, Xiao Y, Gan YW, Gao Q, Bai YY, Wang JM, Zhang L, Tang XC, Hu X, Gong L, Liu Y, Li DW
Frontiers in cell and developmental biology 2021;9:660494
Frontiers in cell and developmental biology 2021;9:660494
Platelet-Rich Plasma Induces Autophagy and Promotes Regeneration in Human Dental Pulp Cells.
Xu H, Xu F, Zhao J, Zhou C, Liu J
Frontiers in bioengineering and biotechnology 2021;9:659742
Frontiers in bioengineering and biotechnology 2021;9:659742
BRD7 Promotes Cell Proliferation and Tumor Growth Through Stabilization of c-Myc in Colorectal Cancer.
Zhao R, Liu Y, Wu C, Li M, Wei Y, Niu W, Yang J, Fan S, Xie Y, Li H, Wang W, Zeng Z, Xiong W, Li X, Li G, Zhou M
Frontiers in cell and developmental biology 2021;9:659392
Frontiers in cell and developmental biology 2021;9:659392
BMSC-Derived Small Extracellular Vesicles Induce Cartilage Reconstruction of Temporomandibular Joint Osteoarthritis via Autotaxin-YAP Signaling Axis.
Wang Y, Zhao M, Li W, Yang Y, Zhang Z, Ma R, Wu M
Frontiers in cell and developmental biology 2021;9:656153
Frontiers in cell and developmental biology 2021;9:656153
LINC00511/miRNA-143-3p Modulates Apoptosis and Malignant Phenotype of Bladder Carcinoma Cells via PCMT1.
Dong LM, Zhang XL, Mao MH, Li YP, Zhang XY, Xue DW, Liu YL
Frontiers in cell and developmental biology 2021;9:650999
Frontiers in cell and developmental biology 2021;9:650999
Urea as a By-Product of Ammonia Metabolism Can Be a Potential Serum Biomarker of Hepatocellular Carcinoma.
Bai C, Wang H, Dong D, Li T, Yu Z, Guo J, Zhou W, Li D, Yan R, Wang L, Wang Z, Li Y, Ren L
Frontiers in cell and developmental biology 2021;9:650748
Frontiers in cell and developmental biology 2021;9:650748
Inhibition of JAK-STAT Signaling Pathway Alleviates Age-Related Phenotypes in Tendon Stem/Progenitor Cells.
Chen M, Xiao L, Dai G, Lu P, Zhang Y, Li Y, Ni M, Rui Y
Frontiers in cell and developmental biology 2021;9:650250
Frontiers in cell and developmental biology 2021;9:650250
β-Arrestin1 Promotes Colorectal Cancer Metastasis Through GSK-3β/β-Catenin Signaling- Mediated Epithelial-to-Mesenchymal Transition.
Song Q, Han Z, Wu X, Wang Y, Zhou L, Yang L, Liu N, Sui H, Cai J, Ji Q, Li Q
Frontiers in cell and developmental biology 2021;9:650067
Frontiers in cell and developmental biology 2021;9:650067
Cartilage Endplate Stem Cells Transdifferentiate Into Nucleus Pulposus Cells via Autocrine Exosomes.
Luo L, Gong J, Zhang H, Qin J, Li C, Zhang J, Tang Y, Zhang Y, Chen J, Zhou Y, Tian Z, Liu Y, Liu M
Frontiers in cell and developmental biology 2021;9:648201
Frontiers in cell and developmental biology 2021;9:648201
CORO6 Promotes Cell Growth and Invasion of Clear Cell Renal Cell Carcinoma via Activation of WNT Signaling.
Wang X, Xiao Y, Li S, Yan Z, Luo G
Frontiers in cell and developmental biology 2021;9:647301
Frontiers in cell and developmental biology 2021;9:647301
TAp63α Is Involved in Tobacco Smoke-Induced Lung Cancer EMT and the Anti-cancer Activity of Curcumin via miR-19 Transcriptional Suppression.
Xie C, Zhu J, Yang X, Huang C, Zhou L, Meng Z, Li X, Zhong C
Frontiers in cell and developmental biology 2021;9:645402
Frontiers in cell and developmental biology 2021;9:645402
Hypoxia-Induced LIN28A mRNA Promotes the Metastasis of Colon Cancer in a Protein-Coding-Independent Manner.
Weng M, Feng Y, He Y, Yang W, Li J, Zhu Y, Wang T, Wang C, Zhang X, Qiao Y, Li Q, Zhao L, Gao S, Zhang L, Wu Y, Zhao R, Wang G, Li Z, Jin X, Zheng T, Li X
Frontiers in cell and developmental biology 2021;9:642930
Frontiers in cell and developmental biology 2021;9:642930
A Novel CpG Methylation Risk Indicator for Predicting Prognosis in Bladder Cancer.
Guo Y, Yin J, Dai Y, Guan Y, Chen P, Chen Y, Huang C, Lu YJ, Zhang L, Song D
Frontiers in cell and developmental biology 2021;9:642650
Frontiers in cell and developmental biology 2021;9:642650
Exosomal miR-3682-3p Suppresses Angiogenesis by Targeting ANGPT1 via the RAS-MEK1/2-ERK1/2 Pathway in Hepatocellular Carcinoma.
Dong SS, Dong DD, Yang ZF, Zhu GQ, Gao DM, Chen J, Zhao Y, Liu BB
Frontiers in cell and developmental biology 2021;9:633358
Frontiers in cell and developmental biology 2021;9:633358
Establishment of an Efficient Primary Culture System for Human Hair Follicle Stem Cells Using the Rho-Associated Protein Kinase Inhibitor Y-27632.
Wen L, Miao Y, Fan Z, Zhang J, Guo Y, Dai D, Huang J, Liu Z, Chen R, Hu Z
Frontiers in cell and developmental biology 2021;9:632882
Frontiers in cell and developmental biology 2021;9:632882
Grb2 Induces Cardiorenal Syndrome Type 3: Roles of IL-6, Cardiomyocyte Bioenergetics, and Akt/mTOR Pathway.
Wang J, Sun X, Wang X, Cui S, Liu R, Liu J, Fu B, Gong M, Wang C, Shi Y, Chen Q, Cai G, Chen X
Frontiers in cell and developmental biology 2021;9:630412
Frontiers in cell and developmental biology 2021;9:630412
Extracellular Vesicles Carry lncRNA SNHG16 to Promote Metastasis of Breast Cancer Cells via the miR-892b/PPAPDC1A Axis.
Xia W, Liu Y, Cheng T, Xu T, Dong M, Hu X
Frontiers in cell and developmental biology 2021;9:628573
Frontiers in cell and developmental biology 2021;9:628573
The Protective Effect of 1,25(OH)(2)D(3) on Myocardial Function is Mediated via Sirtuin 3-Regulated Fatty Acid Metabolism.
Yang J, Zhang Y, Pan Y, Sun C, Liu Z, Liu N, Fu Y, Li X, Li Y, Kong J
Frontiers in cell and developmental biology 2021;9:627135
Frontiers in cell and developmental biology 2021;9:627135
LUZP1 Controls Cell Division, Migration and Invasion Through Regulation of the Actin Cytoskeleton.
Bozal-Basterra L, Gonzalez-Santamarta M, Muratore V, Martín-Martín N, Ercilla A, Rodríguez JA, Carracedo A, Sutherland JD, Barrio R
Frontiers in cell and developmental biology 2021;9:624089
Frontiers in cell and developmental biology 2021;9:624089
High-Fat Diet Induced Gut Microbiota Alterations Associating With Ghrelin/Jak2/Stat3 Up-Regulation to Promote Benign Prostatic Hyperplasia Development.
Gu M, Liu C, Yang T, Zhan M, Cai Z, Chen Y, Chen Q, Wang Z
Frontiers in cell and developmental biology 2021;9:615928
Frontiers in cell and developmental biology 2021;9:615928
Hypoglycemic Efficacy of Rh-aFGF Variants in Treatment of Diabetes in ZDF Rats.
Zhang L, Zhou Q, Chen M, Yang X, Lu C, Sun W, Hui Q, Wang X
Frontiers in cell and developmental biology 2021;9:609383
Frontiers in cell and developmental biology 2021;9:609383
Deficiency of Sirtuin 1 Impedes Endometrial Decidualization in Recurrent Implantation Failure Patients.
Li J, Qi J, Yao G, Zhu Q, Li X, Xu R, Zhu Z, Zhao H, Wang Y, Ding Y, Sun Y
Frontiers in cell and developmental biology 2021;9:598364
Frontiers in cell and developmental biology 2021;9:598364
Retinoic Acid Signaling Plays a Crucial Role in Excessive Caffeine Intake-Disturbed Apoptosis and Differentiation of Myogenic Progenitors.
Wu N, Li Y, He X, Lin J, Long D, Cheng X, Brand-Saberi B, Wang G, Yang X
Frontiers in cell and developmental biology 2021;9:586767
Frontiers in cell and developmental biology 2021;9:586767
MNSFβ Promotes the Proliferation and Migration of Human Extravillous Trophoblast Cells and the Villus Expression Level of MNSFβ Is Decreased in Recurrent Miscarriage Patients.
Wang N, Yang Q, Gu Y, Zhen X, Shi Y, Gu W, Wang J, He Y, Wang J
Gynecologic and obstetric investigation 2021;86(1-2):27-39
Gynecologic and obstetric investigation 2021;86(1-2):27-39
Rutaecarpine Inhibits Doxorubicin-Induced Oxidative Stress and Apoptosis by Activating AKT Signaling Pathway.
Liao ZQ, Jiang YN, Su ZL, Bi HL, Li JT, Li CL, Yang XL, Zhang Y, Xie X
Frontiers in cardiovascular medicine 2021;8:809689
Frontiers in cardiovascular medicine 2021;8:809689
JMJD1A/NR4A1 Signaling Regulates the Procession of Renal Tubular Epithelial Interstitial Fibrosis Induced by AGEs in HK-2.
Wang S, Zuo A, Jiang W, Xie J, Lin H, Sun W, Zhao M, Xia J, Shao J, Zhao X, Liang D, Yang A, Sun J, Wang M
Frontiers in medicine 2021;8:807694
Frontiers in medicine 2021;8:807694
Characterization of an Aging-Based Diagnostic Gene Signature and Molecular Subtypes With Diverse Immune Infiltrations in Atherosclerosis.
Zhao L, Lv F, Zheng Y, Yan L, Cao X
Frontiers in molecular biosciences 2021;8:792540
Frontiers in molecular biosciences 2021;8:792540
Sirt1 Promotes the Restoration of Hepatic Progenitor Cell (HPC)-Mediated Liver Fatty Injury in NAFLD Through Activating the Wnt/β-Catenin Signal Pathway.
Li Q, Gong Y, Wang Y, Liu B, Chu Y, Gui S, Zheng Y, Chen X
Frontiers in nutrition 2021;8:791861
Frontiers in nutrition 2021;8:791861
NAP1L5 Promotes Nucleolar Hypertrophy and Is Required for Translation Activation During Cardiomyocyte Hypertrophy.
Guo N, Zheng D, Sun J, Lv J, Wang S, Fang Y, Zhao Z, Zeng S, Guo Q, Tong J, Wang Z
Frontiers in cardiovascular medicine 2021;8:791501
Frontiers in cardiovascular medicine 2021;8:791501
Validated Impacts of N6-Methyladenosine Methylated mRNAs on Apoptosis and Angiogenesis in Myocardial Infarction Based on MeRIP-Seq Analysis.
Zhang Y, Hua W, Dang Y, Cheng Y, Wang J, Zhang X, Teng M, Wang S, Zhang M, Kong Z, Lu X, Zheng Y
Frontiers in molecular biosciences 2021;8:789923
Frontiers in molecular biosciences 2021;8:789923
MAP3K8 Is a Prognostic Biomarker and Correlated With Immune Response in Glioma.
Ren J, Xu Y, Liu J, Wu S, Zhang R, Cao H, Sun J
Frontiers in molecular biosciences 2021;8:779290
Frontiers in molecular biosciences 2021;8:779290
Microenvironment Stiffness Amplifies Post-ischemia Heart Regeneration in Response to Exogenous Extracellular Matrix Proteins in Neonatal Mice.
Wang X, Pierre V, Senapati S, Park PS, Senyo SE
Frontiers in cardiovascular medicine 2021;8:773978
Frontiers in cardiovascular medicine 2021;8:773978
Maslinic Acid Attenuates Ischemia/Reperfusion Injury-Induced Myocardial Inflammation and Apoptosis by Regulating HMGB1-TLR4 Axis.
Li Q, Xu M, Li Z, Li T, Wang Y, Chen Q, Wang Y, Feng J, Yin X, Lu C
Frontiers in cardiovascular medicine 2021;8:768947
Frontiers in cardiovascular medicine 2021;8:768947
Vanadium Induces Oxidative Stress and Mitochondrial Quality Control Disorder in the Heart of Ducks.
Xiong Z, Xing C, Xu T, Yang Y, Liu G, Hu G, Cao H, Zhang C, Guo X, Yang F
Frontiers in veterinary science 2021;8:756534
Frontiers in veterinary science 2021;8:756534
Development and Validation of Ten-RNA Binding Protein Signature Predicts Overall Survival in Osteosarcoma.
Zhang J, Miao X, Wu T, Jia J, Cheng X
Frontiers in molecular biosciences 2021;8:751842
Frontiers in molecular biosciences 2021;8:751842
The Role of Sorting Nexin 17 in Cardiac Development.
Wu Y, Zhou Y, Huang J, Ma K, Yuan T, Jiang Y, Ye M, Li J
Frontiers in cardiovascular medicine 2021;8:748891
Frontiers in cardiovascular medicine 2021;8:748891
Single-Cell Profiles of Age-Related Osteoarthritis Uncover Underlying Heterogeneity Associated With Disease Progression.
Liu W, Chen Y, Zeng G, Yang S, Yang T, Ma M, Song W
Frontiers in molecular biosciences 2021;8:748360
Frontiers in molecular biosciences 2021;8:748360
Methylation and Expression of the Exercise-Related TLR1 Gene Is Associated With Low Grade Glioma Prognosis and Outcome.
Lu L, Hu Y, Wang C, Jiang F, Wu C
Frontiers in molecular biosciences 2021;8:747933
Frontiers in molecular biosciences 2021;8:747933
Comprehensive Analysis of REST/NRSF Gene in Glioma and Its ceRNA Network Identification.
Zhang Y, Wang Q, Wang Z, Zhang C, Xu X, Xu J, Ren H, Shao X, Zhen X, Zhang L, Yu Y
Frontiers in medicine 2021;8:739624
Frontiers in medicine 2021;8:739624
S-Propargyl-Cysteine Attenuates Diabetic Cardiomyopathy in db/db Mice Through Activation of Cardiac Insulin Receptor Signaling.
Li Y, Xie KF, Chang YH, Wang C, Chen Y, Wang MJ, Zhu YC
Frontiers in cardiovascular medicine 2021;8:737191
Frontiers in cardiovascular medicine 2021;8:737191
Mechanically Activated Calcium Channel PIEZO1 Modulates Radiation-Induced Epithelial-Mesenchymal Transition by Forming a Positive Feedback With TGF-β1.
Huang JQ, Zhang H, Guo XW, Lu Y, Wang SN, Cheng B, Dong SH, Lyu XL, Li FS, Li YW
Frontiers in molecular biosciences 2021;8:725275
Frontiers in molecular biosciences 2021;8:725275
PIEZO1 Ion Channel Mediates Ionizing Radiation-Induced Pulmonary Endothelial Cell Ferroptosis via Ca(2+)/Calpain/VE-Cadherin Signaling.
Guo XW, Zhang H, Huang JQ, Wang SN, Lu Y, Cheng B, Dong SH, Wang YY, Li FS, Li YW
Frontiers in molecular biosciences 2021;8:725274
Frontiers in molecular biosciences 2021;8:725274
Developmental Angiogenesis Requires the Mitochondrial Phenylalanyl-tRNA Synthetase.
Li B, Chen K, Liu F, Zhang J, Chen X, Chen T, Chen Q, Yao Y, Hu W, Wang L, Wu Y
Frontiers in cardiovascular medicine 2021;8:724846
Frontiers in cardiovascular medicine 2021;8:724846
Expression of LOX Suggests Poor Prognosis in Gastric Cancer.
Zhu J, Luo C, Zhao J, Zhu X, Lin K, Bu F, Yu Z, Zou F, Zhu Z
Frontiers in medicine 2021;8:718986
Frontiers in medicine 2021;8:718986
MiR-3064 in Epicardial Adipose-Derived Exosomes Targets Neuronatin to Regulate Adipogenic Differentiation of Epicardial Adipose Stem Cells.
Yang W, Tu H, Tang K, Huang H, Ou S, Wu J
Frontiers in cardiovascular medicine 2021;8:709079
Frontiers in cardiovascular medicine 2021;8:709079
Development and Verification of a Hypoxic Gene Signature for Predicting Prognosis, Immune Microenvironment, and Chemosensitivity for Osteosarcoma.
Wu F, Xu J, Jin M, Jiang X, Li J, Li X, Chen Z, Nie J, Meng Z, Wang G
Frontiers in molecular biosciences 2021;8:705148
Frontiers in molecular biosciences 2021;8:705148
CUX1 Facilitates the Development of Oncogenic Properties Via Activating Wnt/β-Catenin Signaling Pathway in Glioma.
Feng F, Zhao Z, Zhou Y, Cheng Y, Wu X, Heng X
Frontiers in molecular biosciences 2021;8:705008
Frontiers in molecular biosciences 2021;8:705008
Expression and Functional Analysis of lncRNAs Involved in Platelet-Derived Growth Factor-BB-Induced Proliferation of Human Aortic Smooth Muscle Cells.
Lin JJ, Chen W, Gong M, Xu X, Du MY, Wang SF, Yang LY, Wang Y, Liu KX, Kong P, Li B, Liu K, Li YM, Dong LH, Sun SG
Frontiers in cardiovascular medicine 2021;8:702718
Frontiers in cardiovascular medicine 2021;8:702718
Traditional Chinese Medication Qiliqiangxin Attenuates Diabetic Cardiomyopathy via Activating PPARγ.
Wu X, Zhang T, Lyu P, Chen M, Ni G, Cheng H, Xu G, Li X, Wang L, Shang H
Frontiers in cardiovascular medicine 2021;8:698056
Frontiers in cardiovascular medicine 2021;8:698056
ZEB1 Mediates Bone Marrow Mesenchymal Stem Cell Osteogenic Differentiation Partly via Wnt/β-Catenin Signaling.
Xu C, Shi H, Jiang X, Fan Y, Huang D, Qi X, Cheng Q
Frontiers in molecular biosciences 2021;8:682728
Frontiers in molecular biosciences 2021;8:682728
Whole-Transcriptome Analysis of LncRNAs Mediated ceRNA Regulation in Granulosa Cells Isolated From Healthy and Atresia Follicles of Chinese Buffalo.
Pan Y, Yang S, Cheng J, Lv Q, Xing Q, Zhang R, Liang J, Shi D, Deng Y
Frontiers in veterinary science 2021;8:680182
Frontiers in veterinary science 2021;8:680182
CRISPR/dCas9-Mediated Parkin Inhibition Impairs Mitophagy and Aggravates Apoptosis of Rat Nucleus Pulposus Cells Under Oxidative Stress.
Lan T, Zheng YC, Li ND, Chen XS, Shen Z, Yan B
Frontiers in molecular biosciences 2021;8:674632
Frontiers in molecular biosciences 2021;8:674632
Pharmacological Activating Transcription Factor 6 Activation Is Beneficial for Liver Retrieval With ex vivo Normothermic Mechanical Perfusion From Cardiac Dead Donor Rats.
Cheng N, Shi JH, Jin Y, Shi YB, Liu XD, Zhang HP, Cao SL, Yang H, Guo WZ, Zhang SJ
Frontiers in surgery 2021;8:665260
Frontiers in surgery 2021;8:665260
Identification of Proteomic Signatures in Chronic Obstructive Pulmonary Disease Emphysematous Phenotype.
Bai S, Ye R, Wang C, Sun P, Wang D, Yue Y, Wang H, Wu S, Yu M, Xi S, Zhao L
Frontiers in molecular biosciences 2021;8:650604
Frontiers in molecular biosciences 2021;8:650604
WDR45 Mutation Impairs the Autophagic Degradation of Transferrin Receptor and Promotes Ferroptosis.
Xiong Q, Li X, Li W, Chen G, Xiao H, Li P, Wu C
Frontiers in molecular biosciences 2021;8:645831
Frontiers in molecular biosciences 2021;8:645831
Antiretroviral Drugs Regulate Epigenetic Modification of Cardiac Cells Through Modulation of H3K9 and H3K27 Acetylation.
Kashyap S, Mukker A, Gupta D, Datta PK, Rappaport J, Jacobson JM, Ebert SN, Gupta MK
Frontiers in cardiovascular medicine 2021;8:634774
Frontiers in cardiovascular medicine 2021;8:634774
Acitretin Promotes the Differentiation of Myeloid-Derived Suppressor Cells in the Treatment of Psoriasis.
Liu P, Peng C, Chen X, Wu L, Yin M, Li J, Qin Q, Kuang Y, Zhu W
Frontiers in medicine 2021;8:625130
Frontiers in medicine 2021;8:625130
Tanshinone IIA Combined With Cyclosporine A Alleviates Lung Apoptosis Induced by Renal Ischemia-Reperfusion in Obese Rats.
Tai H, Jiang XL, Song N, Xiao HH, Li Y, Cheng MJ, Yin XM, Chen YR, Yang GL, Jiang XY, Kuang JS, Lan ZM, Jia LQ
Frontiers in medicine 2021;8:617393
Frontiers in medicine 2021;8:617393
CYP2C8 Suppress Proliferation, Migration, Invasion and Sorafenib Resistance of Hepatocellular Carcinoma via PI3K/Akt/p27(kip1) Axis.
Zhou X, Li TM, Luo JZ, Lan CL, Wei ZL, Fu TH, Liao XW, Zhu GZ, Ye XP, Peng T
Journal of hepatocellular carcinoma 2021;8:1323-1338
Journal of hepatocellular carcinoma 2021;8:1323-1338
Cannabisin D from Sinomenium Acutum Inhibits Proliferation and Migration of Glioblastoma Cells through MAPKs Signaling.
Zhang D, Li C, Zhang L, Li B, Wang Y, Wang R, Chen Z, Xu L, Liu T
Nutrition and cancer 2021;73(11-12):2491-2501
Nutrition and cancer 2021;73(11-12):2491-2501
The mechanism and candidate compounds of aged citrus peel (chenpi) preventing chronic obstructive pulmonary disease and its progression to lung cancer.
Zhou L, Gu W, Kui F, Gao F, Niu Y, Li W, Zhang Y, Guo L, Wang J, Guo Z, Du G
Food & nutrition research 2021;65
Food & nutrition research 2021;65
Disulfiram Chelated with Copper Promotes Apoptosis in Osteosarcoma via ROS/Mitochondria Pathway.
Ren Y, Lin Y, Chen J, Jin Y
Biological & pharmaceutical bulletin 2021;44(10):1557-1564
Biological & pharmaceutical bulletin 2021;44(10):1557-1564
Discovery and Verification of Key Liver Cancer Genes and Alternative Splicing Events Based on Second-Generation Sequencing Data Analysis.
Cui M, Bai M, Zheng L, Bao Y, Sun L, Yu C, Sun Y, Song Z, Wang G, Yu Z, Li Y, Huang Y
Biological & pharmaceutical bulletin 2021;44(10):1433-1444
Biological & pharmaceutical bulletin 2021;44(10):1433-1444
Knockdown of GPSM1 Inhibits the Proliferation and Promotes the Apoptosis of B-Cell Acute Lymphoblastic Leukemia Cells by Suppressing the ADCY6-RAPGEF3-JNK Signaling Pathway.
Zhang Y, Zhou B, Sun J, He Q, Zhao Y
Pathology oncology research : POR 2021;27:643376
Pathology oncology research : POR 2021;27:643376
Suppression of DLBCL Progression by the E3 Ligase Trim35 Is Mediated by CLOCK Degradation and NK Cell Infiltration.
Tan X, Cao F, Tang F, Lu C, Yu Q, Feng S, Yang Z, Chen S, He X, He J, Weng L, Sun L
Journal of immunology research 2021;2021:9995869
Journal of immunology research 2021;2021:9995869
TNPO1-Mediated Nuclear Import of FUBP1 Contributes to Tumor Immune Evasion by Increasing NRP1 Expression in Cervical Cancer.
Yang B, Chen J, Teng Y
Journal of immunology research 2021;2021:9994004
Journal of immunology research 2021;2021:9994004
MiR-21-3p Inhibits Adipose Browning by Targeting FGFR1 and Aggravates Atrial Fibrosis in Diabetes.
Pan JA, Lin H, Yu JY, Zhang HL, Zhang JF, Wang CQ, Gu J
Oxidative medicine and cellular longevity 2021;2021:9987219
Oxidative medicine and cellular longevity 2021;2021:9987219
PIN1 Protects Hair Cells and Auditory HEI-OC1 Cells against Senescence by Inhibiting the PI3K/Akt/mTOR Pathway.
Zhang Y, Lv Z, Liu Y, Cao H, Yang J, Wang B
Oxidative medicine and cellular longevity 2021;2021:9980444
Oxidative medicine and cellular longevity 2021;2021:9980444
Lipidomic Alterations and PPARα Activation Induced by Resveratrol Lead to Reduction in Lesion Size in Endometriosis Models.
Chen Z, Wang C, Lin C, Zhang L, Zheng H, Zhou Y, Li X, Li C, Zhang X, Yang X, Guan M, Xi Y
Oxidative medicine and cellular longevity 2021;2021:9979953
Oxidative medicine and cellular longevity 2021;2021:9979953
Y-Box Binding Protein 1 Regulates Angiogenesis in Bladder Cancer via miR-29b-3p-VEGFA Pathway.
Gao D, Niu Q, Gong Y, Guo Q, Zhang S, Wang Y, Liu S, Wang H, Svatek R, Rodriguez R, Ma J, Wang Z
Journal of oncology 2021;2021:9913015
Journal of oncology 2021;2021:9913015
Benefit Effect of Dendrobium officinale Ultrafine Powder on DSS-Induced Ulcerative Colitis Rats by Improving Colon Mucosal Barrier.
Zheng X, Xiong TX, Zhang K, Zhou FC, Wang HY, Li B, Dong YJ, He X, Li LZ, Yu QX, Lv GY, Chen SH
Evidence-based complementary and alternative medicine : eCAM 2021;2021:9658638
Evidence-based complementary and alternative medicine : eCAM 2021;2021:9658638
VIP Stabilizes the Cytoskeleton of Schlemm's Canal Endothelia via Reducing Caspase-3 Mediated ZO-1 Endolysosomal Degradation.
Lou X, Mou Q, Zhao B, Huang J, Yao K, Luo Z, Ye M, Hu Y, Duan Q, Li X, Wen Z, Chen Z, Zhang H, Zhao Y
Oxidative medicine and cellular longevity 2021;2021:9397960
Oxidative medicine and cellular longevity 2021;2021:9397960
Pan-Cancer Analyses of the Tumor Microenvironment Reveal That Ubiquitin-Conjugating Enzyme E2C Might Be a Potential Immunotherapy Target.
Huang GZ, Chen ZQ, Wu J, Shao TR, Zou C, Ai YL, Lv XZ
Journal of immunology research 2021;2021:9250207
Journal of immunology research 2021;2021:9250207
Effect and Mechanism of LRP6 on Cardiac Myocyte Ferroptosis in Myocardial Infarction.
Li RL, Fan CH, Gong SY, Kang S
Oxidative medicine and cellular longevity 2021;2021:8963987
Oxidative medicine and cellular longevity 2021;2021:8963987
Tetrandrine Ameliorates Myocardial Ischemia Reperfusion Injury through miR-202-5p/TRPV2.
Zhao W, Wu Y, Ye F, Huang S, Chen H, Zhou R, Jiang W
BioMed research international 2021;2021:8870674
BioMed research international 2021;2021:8870674
P2X7 Receptor Induces Pyroptotic Inflammation and Cartilage Degradation in Osteoarthritis via NF-κB/NLRP3 Crosstalk.
Li Z, Huang Z, Zhang H, Lu J, Tian Y, Wei Y, Yang Y, Bai L
Oxidative medicine and cellular longevity 2021;2021:8868361
Oxidative medicine and cellular longevity 2021;2021:8868361
Oleanolic Acid Induces Autophagy and Apoptosis via the AMPK-mTOR Signaling Pathway in Colon Cancer.
Hu C, Cao Y, Li P, Tang X, Yang M, Gu S, Xiong K, Li T, Xiao T
Journal of oncology 2021;2021:8281718
Journal of oncology 2021;2021:8281718
Protective Effect of Xiao-Xu-Ming Decoction-Mediated Inhibition of ROS/NLRP3 Axis on Lipopolysaccharide-Induced Acute Lung Injury In Vitro and In Vivo.
Xiang Y, Cai M, Li X, Bao X, Cai D
Evidence-based complementary and alternative medicine : eCAM 2021;2021:8257495
Evidence-based complementary and alternative medicine : eCAM 2021;2021:8257495
Trophoblasts Modulate the Ca(2+) Oscillation and Contraction of Myometrial Smooth Muscle Cells by Small Extracellular Vesicle- (sEV-) Mediated Exporting of miR-25-3p during Premature Labor.
Wang L, Zhang W, Zou N, Zhang L
Oxidative medicine and cellular longevity 2021;2021:8140667
Oxidative medicine and cellular longevity 2021;2021:8140667
Functional Analysis of Ectodysplasin-A Mutations in X-Linked Nonsyndromic Hypodontia and Possible Involvement of X-Chromosome Inactivation.
Pan Y, Lu T, Peng L, Zeng Q, Huang X, Yao X, Wu B, Xiong F
Stem cells international 2021;2021:7653013
Stem cells international 2021;2021:7653013
Wenxin Granules Regulate Endoplasmic Reticulum Stress Unfolded Protein Response and Improve Ventricular Remodeling on Rats with Myocardial Infarction.
Liu K, Lv M, Ji X, Lou L, Nie B, Zhao J, Wu A, Zhao M
Evidence-based complementary and alternative medicine : eCAM 2021;2021:7375549
Evidence-based complementary and alternative medicine : eCAM 2021;2021:7375549
Limonin Inhibits IL-1β-Induced Inflammation and Catabolism in Chondrocytes and Ameliorates Osteoarthritis by Activating Nrf2.
Jin J, Lv X, Wang B, Ren C, Jiang J, Chen H, Chen X, Gu M, Pan Z, Tian N, Wu A, Sun L, Gao W, Wang X, Zhang X, Wu Y, Zhou Y
Oxidative medicine and cellular longevity 2021;2021:7292512
Oxidative medicine and cellular longevity 2021;2021:7292512
Trehalose Ameliorates Diabetic Cardiomyopathy: Role of the PK2/PKR Pathway.
Liu Y, Wu S, Zhao Q, Yang Z, Yan X, Li C, Zha W, Yu W
Oxidative medicine and cellular longevity 2021;2021:6779559
Oxidative medicine and cellular longevity 2021;2021:6779559
Pentoxifylline Can Reduce the Inflammation Caused by LPS after Inhibiting Autophagy in RAW264.7 Macrophage Cells.
Ruan D, Deng S, Liu Z, He J
BioMed research international 2021;2021:6698366
BioMed research international 2021;2021:6698366
RBM23 Drives Hepatocellular Carcinoma by Activating NF-κB Signaling Pathway.
Han H, Lin T, Fang Z, Zhou G
BioMed research international 2021;2021:6697476
BioMed research international 2021;2021:6697476
Ganoderma lucidum Spore Polysaccharide Inhibits the Growth of Hepatocellular Carcinoma Cells by Altering Macrophage Polarity and Induction of Apoptosis.
Song M, Li ZH, Gu HS, Tang RY, Zhang R, Zhu YL, Liu JL, Zhang JJ, Wang LY
Journal of immunology research 2021;2021:6696606
Journal of immunology research 2021;2021:6696606
Dendrobium officinale Regulates Fatty Acid Metabolism to Ameliorate Liver Lipid Accumulation in NAFLD Mice.
Lei SS, Zhang NY, Zhou FC, He X, Wang HY, Li LZ, Zheng X, Dong YJ, Luo R, Li B, Jin HY, Yu QX, Lv GY, Chen SH
Evidence-based complementary and alternative medicine : eCAM 2021;2021:6689727
Evidence-based complementary and alternative medicine : eCAM 2021;2021:6689727
Nardosinone Alleviates Parkinson's Disease Symptoms in Mice by Regulating Dopamine D2 Receptor.
Bian LH, Yao ZW, Zhao CB, Li QY, Shi JL, Guo JY
Evidence-based complementary and alternative medicine : eCAM 2021;2021:6686965
Evidence-based complementary and alternative medicine : eCAM 2021;2021:6686965
Ferroportin-Dependent Iron Homeostasis Protects against Oxidative Stress-Induced Nucleus Pulposus Cell Ferroptosis and Ameliorates Intervertebral Disc Degeneration In Vivo.
Lu S, Song Y, Luo R, Li S, Li G, Wang K, Liao Z, Wang B, Ke W, Xiang Q, Chen C, Wu X, Zhang Y, Ling L, Yang C
Oxidative medicine and cellular longevity 2021;2021:6670497
Oxidative medicine and cellular longevity 2021;2021:6670497
Melatonin Alleviates Contrast-Induced Acute Kidney Injury by Activation of Sirt3.
Zhang C, Suo M, Liu L, Qi Y, Zhang C, Xie L, Zheng X, Ma C, Li J, Yang J, Bu P
Oxidative medicine and cellular longevity 2021;2021:6668887
Oxidative medicine and cellular longevity 2021;2021:6668887
Exercise Reduces Morphine-Induced Hyperalgesia and Antinociceptive Tolerance.
Gong X, Fan R, Zhu Q, Ye X, Chen Y, Zhang M
BioMed research international 2021;2021:6667474
BioMed research international 2021;2021:6667474
Identification of Immune-Related Prognostic Biomarkers Associated with HPV-Positive Head and Neck Squamous Cell Carcinoma.
Chen Y, Nie J, Li X, Fan T, Deng X, Liang D, Song G
Journal of immunology research 2021;2021:6661625
Journal of immunology research 2021;2021:6661625
Tantalum Particles Induced Cytotoxic and Inflammatory Effects in Human Monocytes.
Yang Y, Zhang Y, Kang Y, Hu C, Zhang Y, Liang H, You J, Shao L
BioMed research international 2021;2021:6658498
BioMed research international 2021;2021:6658498
Serum Exosomes Derived from Irritable Bowel Syndrome Patient Increase Cell Permeability via Regulating miR-148b-5p/RGS2 Signaling in Human Colonic Epithelium Cells.
Xing Y, Xue S, Wu J, Zhou J, Xing F, Li T, Nie X
Gastroenterology research and practice 2021;2021:6655900
Gastroenterology research and practice 2021;2021:6655900
CDK12 Promotes Cervical Cancer Progression through Enhancing Macrophage Infiltration.
Yang B, Chen J, Teng Y
Journal of immunology research 2021;2021:6645885
Journal of immunology research 2021;2021:6645885
Oxalate Activates Autophagy to Induce Ferroptosis of Renal Tubular Epithelial Cells and Participates in the Formation of Kidney Stones.
Song Q, Liao W, Chen X, He Z, Li D, Li B, Liu J, Liu L, Xiong Y, Song C, Yang S
Oxidative medicine and cellular longevity 2021;2021:6630343
Oxidative medicine and cellular longevity 2021;2021:6630343
HO-1/CO Maintains Intestinal Barrier Integrity through NF-κB/MLCK Pathway in Intestinal HO-1(-/-) Mice.
Zhang Z, Zhang L, Zhang Q, Liu B, Li F, Xin Y, Duan Z
Oxidative medicine and cellular longevity 2021;2021:6620873
Oxidative medicine and cellular longevity 2021;2021:6620873
GPX4-Regulated Ferroptosis Mediates S100-Induced Experimental Autoimmune Hepatitis Associated with the Nrf2/HO-1 Signaling Pathway.
Zhu L, Chen D, Zhu Y, Pan T, Xia D, Cai T, Lin H, Lin J, Jin X, Wu F, Yu S, Zhu K, Xu L, Chen Y
Oxidative medicine and cellular longevity 2021;2021:6551069
Oxidative medicine and cellular longevity 2021;2021:6551069
MicroRNA Hsa-Let-7b Regulates the Osteogenic Differentiation of Human Periodontal Ligament Stem Cells by Targeting CTHRC1.
Fu L, Li N, Ye Y, Ye X, Xiao T, Wu X, Ma Y, Yu J
Stem cells international 2021;2021:5791181
Stem cells international 2021;2021:5791181
RNA-Seq Profiling to Investigate the Mechanism of Qishen Granules on Regulating Mitochondrial Energy Metabolism of Heart Failure in Rats.
He H, Li C, Lu X, Li Y, Li X, Sun X, Tang B, Wu Y, Li C
Evidence-based complementary and alternative medicine : eCAM 2021;2021:5779307
Evidence-based complementary and alternative medicine : eCAM 2021;2021:5779307
Treatment of Radiation Bone Injury with Transplanted hUCB-MSCs via Wnt/β-Catenin.
Zhang Y, Deng H, Yang Z, Chen Z, Zhang S, Zhu Y, Yang M, Zhong H, Zhou F, Xie Y, Cai L
Stem cells international 2021;2021:5660927
Stem cells international 2021;2021:5660927
Babao Dan Reverses Multiple-Drug Resistance in Gastric Cancer Cells via Triggering Apoptosis and Autophagy and Inhibiting PI3K/AKT/mTOR Signaling.
Zhao J, Lan W, Peng J, Guan B, Liu J, Zhang M, Zhan Z, Lin J
Evidence-based complementary and alternative medicine : eCAM 2021;2021:5631942
Evidence-based complementary and alternative medicine : eCAM 2021;2021:5631942
lncRNA HHIP-AS1 Promotes the Osteogenic Differentiation Potential and Inhibits the Migration Ability of Periodontal Ligament Stem Cells.
Qin Q, Yang H, Zhang C, Han X, Guo J, Fan Z, Guo J
Stem cells international 2021;2021:5595580
Stem cells international 2021;2021:5595580
Tubeimoside I Ameliorates Myocardial Ischemia-Reperfusion Injury through SIRT3-Dependent Regulation of Oxidative Stress and Apoptosis.
Lv D, Luo M, Cheng Z, Wang R, Yang X, Guo Y, Huang L, Li X, Huang B, Shen J, Luo S, Yan J
Oxidative medicine and cellular longevity 2021;2021:5577019
Oxidative medicine and cellular longevity 2021;2021:5577019
Heat Killed Salmonella typhimurium Protects Intestine Against Radiation Injury Through Wnt Signaling Pathway.
Chen Y, Cao K, Liu H, Liu T, Liu L, Qin H, Liao Z, Hu X, Li B, Liu C, Cai J, Cui J, Gao F, Yang Y
Journal of oncology 2021;2021:5550956
Journal of oncology 2021;2021:5550956
Essential Oil-Rich Chinese Formula Luofushan-Baicao Oil Inhibits the Infection of Influenza A Virus through the Regulation of NF-κB P65 and IRF3 Activation.
Mao X, Gu S, Sang H, Ye Y, Li J, Teng Y, Zhang F, Ma Q, Jiang P, Yang Z, Huang W, Liu S
Evidence-based complementary and alternative medicine : eCAM 2021;2021:5547424
Evidence-based complementary and alternative medicine : eCAM 2021;2021:5547424
TIPE1 Suppresses Growth and Metastasis of Ovarian Cancer.
Zhang Z, Chang M, Song X, Wang K, Sun W, Ma H, Yan X, Sun Y, Song X, Xie L
Journal of oncology 2021;2021:5538911
Journal of oncology 2021;2021:5538911
Pleckstrin-2 as a Prognostic Factor and Mediator of Gastric Cancer Progression.
Wang J, He Z, Sun B, Huang W, Xiang J, Chen Z, Li Z, Gu X
Gastroenterology research and practice 2021;2021:5527387
Gastroenterology research and practice 2021;2021:5527387
LuQi Formula Regulates NLRP3 Inflammasome to Relieve Myocardial-Infarction-Induced Cardiac Remodeling in Mice.
Zhang X, Zhao D, Feng J, Yang X, Lan Z, Yang T, Kong X, Qu H, Zhou H
Evidence-based complementary and alternative medicine : eCAM 2021;2021:5518083
Evidence-based complementary and alternative medicine : eCAM 2021;2021:5518083
METTL3-Mediated m(6)A RNA Modification Regulates Corneal Injury Repair.
Dai Y, Cheng M, Zhang S, Ling R, Wen J, Cheng Y, Huang B, Li J, Dai C, Mao S, Lin S, Shen H, Jiang Y
Stem cells international 2021;2021:5512153
Stem cells international 2021;2021:5512153
CKAP2L, as an Independent Risk Factor, Closely Related to the Prognosis of Glioma.
Zhu L, Zheng Y, Hu R, Hu C
BioMed research international 2021;2021:5486131
BioMed research international 2021;2021:5486131
NR1D1 Deletion Induces Rupture-Prone Vulnerable Plaques by Regulating Macrophage Pyroptosis via the NF-κB/NLRP3 Inflammasome Pathway.
Wu Z, Liao F, Luo G, Qian Y, He X, Xu W, Ding S, Pu J
Oxidative medicine and cellular longevity 2021;2021:5217572
Oxidative medicine and cellular longevity 2021;2021:5217572
Design, Synthesis, and Biological Evaluation of a Novel Aminothiol Compound as Potential Radioprotector.
Li X, Wang X, Miao L, Guo Y, Yuan R, Ren J, Huang Y, Tian H
Oxidative medicine and cellular longevity 2021;2021:4714649
Oxidative medicine and cellular longevity 2021;2021:4714649
The Dietary Supplement γ-Oryzanol Attenuates Hepatic Ischemia Reperfusion Injury via Inhibiting Endoplasmic Reticulum Stress and HMGB1/NLRP3 Inflammasome.
Du Y, Zhong F, Cheng H, Li T, Chen Y, Tan P, Huang M, Liang T, Liu Y, Xia X, Fu W
Oxidative medicine and cellular longevity 2021;2021:4628050
Oxidative medicine and cellular longevity 2021;2021:4628050
Effects of Long Noncoding RNA HOTAIR Targeting miR-138 on Inflammatory Response and Oxidative Stress in Rat Cardiomyocytes Induced by Hypoxia and Reoxygenation.
Wang G, Wang Q, Xu W
Disease markers 2021;2021:4273274
Disease markers 2021;2021:4273274
MCC950, the NLRP3 Inhibitor, Protects against Cartilage Degradation in a Mouse Model of Osteoarthritis.
Ni B, Pei W, Qu Y, Zhang R, Chu X, Wang Y, Huang X, You H
Oxidative medicine and cellular longevity 2021;2021:4139048
Oxidative medicine and cellular longevity 2021;2021:4139048
Hypoxia Enhances Activity and Malignant Behaviors of Colorectal Cancer Cells through the STAT3/MicroRNA-19a/PTEN/PI3K/AKT Axis.
Tang Y, Weng X, Liu C, Li X, Chen C
Analytical cellular pathology (Amsterdam) 2021;2021:4132488
Analytical cellular pathology (Amsterdam) 2021;2021:4132488
Cox-2 Antagonizes the Protective Effect of Sevoflurane on Hypoxia/Reoxygenation-Induced Cardiomyocyte Apoptosis through Inhibiting the Akt Pathway.
Guo C, Zhang L, Gao Y, Sun J, Fan L, Bai Y, Zhang J, Naren G, Yang J, Li L
Disease markers 2021;2021:4114593
Disease markers 2021;2021:4114593
Expression of ANGPTL4 in Nucleus Pulposus Tissues Is Associated with Intervertebral Disc Degeneration.
Liu FJ, Xie LY, Li HZ, Cao SN, Chen YZ, Bin-Shi, Wang DD
Disease markers 2021;2021:3532716
Disease markers 2021;2021:3532716
ULK1 Suppresses Osteoclast Differentiation and Bone Resorption via Inhibiting Syk-JNK through DOK3.
Zhang Y, Zhang S, Wang Y, Yang Z, Chen Z, Wen N, Yang M, Huang Z, Xie Y, Cai L
Oxidative medicine and cellular longevity 2021;2021:2896674
Oxidative medicine and cellular longevity 2021;2021:2896674
Danhong Injection and Trimetazidine Protect Cardiomyocytes and Enhance Calcium Handling after Myocardial Infarction.
Zhang J, Shi X, Gao J, Zhou R, Guo F, Zhang Y, Fan F, Zhai Q, Sun M, Yang H
Evidence-based complementary and alternative medicine : eCAM 2021;2021:2480465
Evidence-based complementary and alternative medicine : eCAM 2021;2021:2480465
Luteolin Improves Cyclophosphamide-Induced Cystitis through TXNIP/NLRP3 and NF-κB Pathways.
Zhang H, Zhao J, Lu Q, Sun B, Liu X, Yang C, Li S, Li L, Yi S, Yang Z, Xu J
Evidence-based complementary and alternative medicine : eCAM 2021;2021:1718709
Evidence-based complementary and alternative medicine : eCAM 2021;2021:1718709
Mitoquinone Protects Podocytes from Angiotensin II-Induced Mitochondrial Dysfunction and Injury via the Keap1-Nrf2 Signaling Pathway.
Zhu Z, Liang W, Chen Z, Hu J, Feng J, Cao Y, Ma Y, Ding G
Oxidative medicine and cellular longevity 2021;2021:1394486
Oxidative medicine and cellular longevity 2021;2021:1394486
Ivabradine Ameliorates Cardiac Function in Heart Failure with Preserved and Reduced Ejection Fraction via Upregulation of miR-133a.
Shao S, Zhang Y, Gong M, Yang Q, Yuan M, Yuan M, Suo Y, Wang X, Li Y, Bao Q, Li G
Oxidative medicine and cellular longevity 2021;2021:1257283
Oxidative medicine and cellular longevity 2021;2021:1257283
circGLI3 Inhibits Oxidative Stress by Regulating the miR-339-5p/VEGFA Axis in IPEC-J2 Cells.
Li ZX, Wang LX, Zhang Y, Chen W, Zeng YQ
BioMed research international 2021;2021:1086206
BioMed research international 2021;2021:1086206
Inhibiting PP2Acα Promotes the Malignant Phenotype of Gastric Cancer Cells through the ATM/METTL3 Axis.
Cheng Z, Gao S, Liang X, Lian C, Chen J, Fang C
BioMed research international 2021;2021:1015293
BioMed research international 2021;2021:1015293
An Integrated Transcriptomics and Proteomics Analysis Implicates lncRNA MALAT1 in the Regulation of Lipid Metabolism.
Wang H, Zhang Y, Guan X, Li X, Zhao Z, Gao Y, Zhang X, Chen R
Molecular & cellular proteomics : MCP 2021;20:100141
Molecular & cellular proteomics : MCP 2021;20:100141
Lack of WDFY4 Aggravates Ovalbumin-Induced Asthma via Enhanced Th2 Cell Differentiation.
Li Y, Wang A, Long F, Gao F, Gao S, Wei S, Liu A, Li X, Sun W, Li J, Liu Q
International archives of allergy and immunology 2021;182(11):1089-1096
International archives of allergy and immunology 2021;182(11):1089-1096
Long noncoding RNA CEBPA-DT promotes cisplatin chemo-resistance through CEBPA/BCL2 mediated apoptosis in oral squamous cellular cancer.
Qiao X, Liu J, Zhu L, Song R, Zhong M, Guo Y
International journal of medical sciences 2021;18(16):3728-3737
International journal of medical sciences 2021;18(16):3728-3737
The expression and clinical significance of TPM4 in hepatocellular carcinoma.
Li L, Ye T, Zhang Q, Li X, Ma L, Yan J
International journal of medical sciences 2021;18(1):169-175
International journal of medical sciences 2021;18(1):169-175
Dual-specificity Phosphatase 9 protects against Cardiac Hypertrophy by targeting ASK1.
Jiang L, Ren L, Guo X, Zhao J, Zhang H, Chen S, Le S, Liu H, Ye P, Chen M, Xia J
International journal of biological sciences 2021;17(9):2193-2204
International journal of biological sciences 2021;17(9):2193-2204
GABAB receptor inhibits tumor progression and epithelial-mesenchymal transition via the regulation of Hippo/YAP1 pathway in colorectal cancer.
Wang H, Zhang H, Sun Z, Chen W, Miao C
International journal of biological sciences 2021;17(8):1953-1962
International journal of biological sciences 2021;17(8):1953-1962
MicroRNA-135b/CAMK2D Axis Contribute to Malignant Progression of Gastric Cancer through EMT Process Remodeling.
Huangfu L, He Q, Han J, Shi J, Li X, Cheng X, Guo T, Du H, Zhang W, Gao X, Luan F, Xing X, Ji J
International journal of biological sciences 2021;17(8):1940-1952
International journal of biological sciences 2021;17(8):1940-1952
NDRG1 regulates Filopodia-induced Colorectal Cancer invasiveness via modulating CDC42 activity.
Aikemu B, Shao Y, Yang G, Ma J, Zhang S, Yang X, Hong H, Yesseyeva G, Huang L, Jia H, Wang C, Zang L, Sun J, Zheng M
International journal of biological sciences 2021;17(7):1716-1730
International journal of biological sciences 2021;17(7):1716-1730
YY1-modulated long non-coding RNA SNHG12 promotes gastric cancer metastasis by activating the miR-218-5p/YWHAZ axis.
Zhang T, Beeharry MK, Wang Z, Zhu Z, Li J, Li C
International journal of biological sciences 2021;17(7):1629-1643
International journal of biological sciences 2021;17(7):1629-1643
PAK5-mediated AIF phosphorylation inhibits its nuclear translocation and promotes breast cancer tumorigenesis.
Xing Y, Li Y, Hu B, Han F, Zhao X, Zhang H, Li Y, Li D, Li J, Jin F, Li F
International journal of biological sciences 2021;17(5):1315-1327
International journal of biological sciences 2021;17(5):1315-1327
Aurka deficiency in the intestinal epithelium promotes age-induced obesity via propionate-mediated AKT activation.
Sun N, Meng F, Zhao J, Li X, Li R, Han J, Chen X, Cheng W, Yang X, Kou Y, Zheng K, Yang J, Ikezoe T
International journal of biological sciences 2021;17(5):1302-1314
International journal of biological sciences 2021;17(5):1302-1314
Characteristics of the PI3K/AKT and MAPK/ERK pathways involved in the maintenance of self-renewal in lung cancer stem-like cells.
Li J, Wang J, Xie D, Pei Q, Wan X, Xing HR, Ye T
International journal of biological sciences 2021;17(5):1191-1202
International journal of biological sciences 2021;17(5):1191-1202
Novel biomarkers for post-contrast acute kidney injury identified from long non-coding RNA expression profiles.
Chen G, Liu B, Chen S, Li H, Liu J, Mai Z, Chen E, Zhou C, Sun G, Guo Z, Lei L, Huang S, Zhang L, Li M, Tan N, Li H, Liao Y, Liu J, Chen J, Liu Y
International journal of biological sciences 2021;17(3):882-896
International journal of biological sciences 2021;17(3):882-896
Linc-KILH potentiates Notch1 signaling through inhibiting KRT19 phosphorylation and promotes the malignancy of hepatocellular carcinoma.
Zhang X, Xu X, Zhang Z, Xue C, Kong Z, Wu S, Yun X, Fu Y, Zhu C, Qin X
International journal of biological sciences 2021;17(3):768-780
International journal of biological sciences 2021;17(3):768-780
ITGB1 enhances the Radioresistance of human Non-small Cell Lung Cancer Cells by modulating the DNA damage response and YAP1-induced Epithelial-mesenchymal Transition.
Li Y, Sun C, Tan Y, Zhang H, Li Y, Zou H
International journal of biological sciences 2021;17(2):635-650
International journal of biological sciences 2021;17(2):635-650
Inhibition of PI3K/AKT signaling via ROS regulation is involved in Rhein-induced apoptosis and enhancement of oxaliplatin sensitivity in pancreatic cancer cells.
Liu Y, Shi C, He Z, Zhu F, Wang M, He R, Zhao C, Shi X, Zhou M, Pan S, Gao Y, Li X, Qin R
International journal of biological sciences 2021;17(2):589-602
International journal of biological sciences 2021;17(2):589-602
SOX13/TRIM11/YAP axis promotes the proliferation, migration and chemoresistance of anaplastic thyroid cancer.
Tang J, Tian Z, Liao X, Wu G
International journal of biological sciences 2021;17(2):417-429
International journal of biological sciences 2021;17(2):417-429
MAD2B-mediated cell cycle reentry of podocytes is involved in the pathogenesis of FSGS.
Bao D, Su H, Lei CT, Tang H, Ye C, Xiong W, He FF, Lin JH, Hammes HP, Zhang C
International journal of biological sciences 2021;17(15):4396-4408
International journal of biological sciences 2021;17(15):4396-4408
Discovery of a novel HDACi structure that inhibits the proliferation of ovarian cancer cells in vivo and in vitro.
Bai M, Cui M, Li M, Yao X, Wu Y, Zheng L, Sun L, Song Q, Wang S, Liu L, Yu C, Huang Y
International journal of biological sciences 2021;17(13):3493-3507
International journal of biological sciences 2021;17(13):3493-3507
Downregulation of miR‑214-3p attenuates mesangial hypercellularity by targeting PTEN‑mediated JNK/c-Jun signaling in IgA nephropathy.
Li Y, Xia M, Peng L, Liu H, Chen G, Wang C, Yuan D, Liu Y, Liu H
International journal of biological sciences 2021;17(13):3343-3355
International journal of biological sciences 2021;17(13):3343-3355
Genome-scale CRISPRa screening identifies MTX1 as a contributor for sorafenib resistance in hepatocellular carcinoma by augmenting autophagy.
Li L, Yu S, Hu Q, Hai Y, Li Y
International journal of biological sciences 2021;17(12):3133-3144
International journal of biological sciences 2021;17(12):3133-3144
CXCL16 Promotes Gastric Cancer Tumorigenesis via ADAM10-Dependent CXCL16/CXCR6 Axis and Activates Akt and MAPK Signaling Pathways.
Han J, Fu R, Chen C, Cheng X, Guo T, Huangfu L, Li X, Du H, Xing X, Ji J
International journal of biological sciences 2021;17(11):2841-2852
International journal of biological sciences 2021;17(11):2841-2852
Ailanthus Altissima-derived Ailanthone enhances Gastric Cancer Cell Apoptosis by Inducing the Repression of Base Excision Repair by Downregulating p23 Expression.
Wang CM, Li HF, Wang XK, Li WG, Su Q, Xiao X, Hao TF, Chen W, Zhang YW, Zhang HY, Wu W, Hu ZR, Zhao GY, Huo MY, He YL, Zhang CH
International journal of biological sciences 2021;17(11):2811-2825
International journal of biological sciences 2021;17(11):2811-2825
Novel Functions of CD147 in the Mitochondria Exacerbates Melanoma Metastasis.
Lu L, Zhang J, Gan P, Wu L, Zhang X, Peng C, Zhou J, Chen X, Su J
International journal of biological sciences 2021;17(1):285-297
International journal of biological sciences 2021;17(1):285-297
COP9 Signalosome Subunit 3 Restricts Neuroinflammatory Responses During Cerebral Ischemia/Reperfusion Injury Through Stabilizing Suppressor of Cytokine Signaling 3 Protein.
Liang E, Li X, Fu W, Zhao C, Yang B, Yang Z
Neuropsychiatric disease and treatment 2021;17:1217-1227
Neuropsychiatric disease and treatment 2021;17:1217-1227
Loss of miR-1469 expression mediates melanoma cell migration and invasion.
DiVincenzo MJ, Barricklow Z, Schwarz E, Moufawad M, Howard JH, Yu L, Chung C, Gru AA, Carson WE 3rd
PloS one 2021;16(9):e0256629
PloS one 2021;16(9):e0256629
A novel mouse line with epididymal initial segment-specific expression of Cre recombinase driven by the endogenous Lcn9 promoter.
Gong QQ, Wang X, Dou ZL, Zhang KY, Liu XG, Gao JG, Sun XY
PloS one 2021;16(7):e0254802
PloS one 2021;16(7):e0254802
Modulation of inflammatory responses by fractalkine signaling in microglia.
Inoue K, Morimoto H, Ohgidani M, Ueki T
PloS one 2021;16(5):e0252118
PloS one 2021;16(5):e0252118
Harmine inhibits breast cancer cell migration and invasion by inducing the degradation of Twist1.
Nafie E, Lolarga J, Lam B, Guo J, Abdollahzadeh E, Rodriguez S, Glackin C, Liu J
PloS one 2021;16(2):e0247652
PloS one 2021;16(2):e0247652
High expression of ENPP1 in high-grade serous ovarian carcinoma predicts poor prognosis and as a molecular therapy target.
Wang H, Ye F, Zhou C, Cheng Q, Chen H
PloS one 2021;16(2):e0245733
PloS one 2021;16(2):e0245733
Downregulation of RAB7 and Caveolin-1 increases MMP-2 activity in renal tubular epithelial cells under hypoxic conditions.
Yu W, Ke X, Li M, Ye P, Peng J, Li H
Open medicine (Warsaw, Poland) 2021;16(1):1428-1437
Open medicine (Warsaw, Poland) 2021;16(1):1428-1437
Copper Nanoparticles Induce Oxidative Stress via the Heme Oxygenase 1 Signaling Pathway in vitro Studies.
Zou L, Cheng G, Xu C, Liu H, Wang Y, Li N, Fan X, Zhu C, Xia W
International journal of nanomedicine 2021;16:1565-1573
International journal of nanomedicine 2021;16:1565-1573
Silica Nanoparticles Promote α-Synuclein Aggregation and Parkinson's Disease Pathology.
Yuan X, Yang Y, Xia D, Meng L, He M, Liu C, Zhang Z
Frontiers in neuroscience 2021;15:807988
Frontiers in neuroscience 2021;15:807988
Convallatoxin Promotes M2 Macrophage Polarization to Attenuate Atherosclerosis Through PPARγ-Integrin α(v)β(5) Signaling Pathway.
Zhang Y, Shi X, Han J, Peng W, Fang Z, Zhou Y, Xu X, Lin J, Xiao F, Zhao L, Lin Y
Drug design, development and therapy 2021;15:803-812
Drug design, development and therapy 2021;15:803-812
A Novel Hydrogen Sulfide Donor Reduces Pilocarpine-Induced Status Epilepticus and Regulates Microglial Inflammatory Profile.
Liu Z, Zhu Z, He Y, Kang Q, Li F, Zhang W, He Y, Lin Y, Huang B, Mo M, Xu P, Zhu X
Frontiers in cellular neuroscience 2021;15:780447
Frontiers in cellular neuroscience 2021;15:780447
Astroglial CB1 Cannabinoid Receptors Mediate CP 55,940-Induced Conditioned Place Aversion Through Cyclooxygenase-2 Signaling in Mice.
Cong J, Lu K, Zou W, Li Z, Guo Z, Tong X, Zheng J, Zhu J, Li S, Zhang W, Guo Y, Gao TM, Chen R
Frontiers in cellular neuroscience 2021;15:772549
Frontiers in cellular neuroscience 2021;15:772549
Astrocyte Pannexin 1 Suppresses LPS-Induced Inflammatory Responses to Protect Neuronal SH-SY5Y Cells.
Ling ZM, Wang Q, Ma Y, Xue P, Gu Y, Cao MH, Wei ZY
Frontiers in cellular neuroscience 2021;15:710820
Frontiers in cellular neuroscience 2021;15:710820
Tetramethylpyrazine Alleviates Behavioral and Psychological Symptoms of Dementia Through Facilitating Hippocampal Synaptic Plasticity in Rats With Chronic Cerebral Hypoperfusion.
Tan Z, Qiu J, Zhang Y, Yang Q, Yin X, Li J, Liu G, Li H, Yang G
Frontiers in neuroscience 2021;15:646537
Frontiers in neuroscience 2021;15:646537
The Ghrelin/Growth Hormone Secretagogue Receptor System Is Involved in the Rapid and Sustained Antidepressant-Like Effect of Paeoniflorin.
Zhang Y, Zhu MZ, Qin XH, Zeng YN, Zhu XH
Frontiers in neuroscience 2021;15:631424
Frontiers in neuroscience 2021;15:631424
Isoquercetin Improves Inflammatory Response in Rats Following Ischemic Stroke.
Shi Y, Chen X, Liu J, Fan X, Jin Y, Gu J, Liang J, Liang X, Wang C
Frontiers in neuroscience 2021;15:555543
Frontiers in neuroscience 2021;15:555543
Activation of GPR18 by Resolvin D2 Relieves Pain and Improves Bladder Function in Cyclophosphamide-Induced Cystitis Through Inhibiting TRPV1.
Lu Q, Yang Y, Zhang H, Chen C, Zhao J, Yang Z, Fan Y, Li L, Feng H, Zhu J, Yi S
Drug design, development and therapy 2021;15:4687-4699
Drug design, development and therapy 2021;15:4687-4699
Bardoxolone-Methyl Prevents Oxidative Stress-Mediated Apoptosis and Extracellular Matrix Degradation in vitro and Alleviates Osteoarthritis in vivo.
Pang Z, Jiang Z, Zhu R, Song C, Tang H, Cao L, Guo C
Drug design, development and therapy 2021;15:3735-3747
Drug design, development and therapy 2021;15:3735-3747
Puerarin Alleviates UUO-Induced Inflammation and Fibrosis by Regulating the NF-κB P65/STAT3 and TGFβ1/Smads Signaling Pathways.
Wang J, Ge S, Wang Y, Liu Y, Qiu L, Li J, Huang X, Sun L
Drug design, development and therapy 2021;15:3697-3708
Drug design, development and therapy 2021;15:3697-3708
Pentamidine Inhibits Ovarian Cancer Cell Proliferation and Migration by Maintaining Stability of PTEN in vitro.
Wu Y, Zhang Z, Kou Z
Drug design, development and therapy 2021;15:2857-2868
Drug design, development and therapy 2021;15:2857-2868
The Effects of M1/M2 Macrophages on the mRNA Expression Profile of Diabetic Glomerular Endothelial Cells.
Li Y, Yu W, He M, Yuan F
Nephron 2021;145(5):568-578
Nephron 2021;145(5):568-578
Inhibition of TGF-β2-induced migration and epithelial-mesenchymal transition in ARPE-19 by sulforaphane.
Huang YB, Liu PP, Zheng H, Yang XX, Yang CC, Liu Y, Liu Y
International journal of ophthalmology 2021;14(7):973-980
International journal of ophthalmology 2021;14(7):973-980
Effect of luteolin on apoptosis and vascular endothelial growth factor in human choroidal melanoma cells.
Shi ML, Chen YF, Liao HF
International journal of ophthalmology 2021;14(2):186-193
International journal of ophthalmology 2021;14(2):186-193
Maxing Shigan Decoction Mitigates Mycoplasma pneumonia-Induced Pyroptosis in A549 Cells via the NLRP3 Inflammasome.
Liu F, Liu T, Sun M, Zhou J, Xue F, Chen S, Chen J, Zhang L
Infection and drug resistance 2021;14:859-867
Infection and drug resistance 2021;14:859-867
LncRNA MCTP1-AS1 Regulates EMT Process in Endometrial Cancer by Targeting the miR-650/SMAD7 Axis.
Gao Q, Huang Q, Li F, Luo F
OncoTargets and therapy 2021;14:751-761
OncoTargets and therapy 2021;14:751-761
Engeletin Protects Against TNF-α-Induced Apoptosis and Reactive Oxygen Species Generation in Chondrocytes and Alleviates Osteoarthritis in vivo.
Wang H, Jiang Z, Pang Z, Qi G, Hua B, Yan Z, Yuan H
Journal of inflammation research 2021;14:745-760
Journal of inflammation research 2021;14:745-760
Proteomic Profiling of Astrocytic O-GlcNAc Transferase-Related Proteins in the Medial Prefrontal Cortex.
Fan J, Zhong QL, Mo R, Lu CL, Ren J, Mo JW, Guo F, Wen YL, Cao X
Frontiers in molecular neuroscience 2021;14:729975
Frontiers in molecular neuroscience 2021;14:729975
Monomeric CRP Aggravates Myocardial Injury After Myocardial Infarction by Polarizing the Macrophage to Pro-Inflammatory Phenotype Through JNK Signaling Pathway.
Zha Z, Cheng Y, Cao L, Qian Y, Liu X, Guo Y, Wang J
Journal of inflammation research 2021;14:7053-7064
Journal of inflammation research 2021;14:7053-7064
Computational Systems Pharmacology, Molecular Docking and Experiments Reveal the Protective Mechanism of Li-Da-Qian Mixture in the Treatment of Glomerulonephritis.
Zhou W, Sha Y, Zeng J, Zhang X, Zhang A, Ge X
Journal of inflammation research 2021;14:6939-6958
Journal of inflammation research 2021;14:6939-6958
Neutrophil Extracellular Traps Augmented Alveolar Macrophage Pyroptosis via AIM2 Inflammasome Activation in LPS-Induced ALI/ARDS.
Li H, Li Y, Song C, Hu Y, Dai M, Liu B, Pan P
Journal of inflammation research 2021;14:4839-4858
Journal of inflammation research 2021;14:4839-4858
A c-Met Inhibitor Suppresses Osteosarcoma Progression via the ERK1/2 Pathway in Human Osteosarcoma Cells.
Chen W, Wu S, Huang Y, Zhang T, Dong H, Zheng X, Chen T, Gong X, Liu G, Zhao X
OncoTargets and therapy 2021;14:4791-4804
OncoTargets and therapy 2021;14:4791-4804
Fatty Acid-Binding Protein 4 (FABP4) Suppresses Proliferation and Migration of Endometrial Cancer Cells via PI3K/Akt Pathway.
Wu Z, Jeong JH, Ren C, Yang L, Ding L, Li F, Jiang D, Zhu Y, Lu J
OncoTargets and therapy 2021;14:3929-3942
OncoTargets and therapy 2021;14:3929-3942
miR-944 Suppresses EGF-Induced EMT in Colorectal Cancer Cells by Directly Targeting GATA6.
Tang J, Gao W, Liu G, Sheng W, Zhou J, Dong Q, Dong M
OncoTargets and therapy 2021;14:2311-2325
OncoTargets and therapy 2021;14:2311-2325
Prognostic Implications of the Complement Protein C1Q and Its Correlation with Immune Infiltrates in Osteosarcoma.
Huang H, Tan M, Zheng L, Yan G, Li K, Lu D, Cui X, He S, Lei D, Zhu B, Zhao J
OncoTargets and therapy 2021;14:1737-1751
OncoTargets and therapy 2021;14:1737-1751
An Apoptotic Gene Signature for the Prognosis of Hepatocellular Carcinoma.
Chen K, Zhu P, Liao Y, Yan L, Feng R, Zhai W
OncoTargets and therapy 2021;14:1589-1604
OncoTargets and therapy 2021;14:1589-1604
Expression and Functional Relevance of ANXA1 in Hypopharyngeal Carcinoma with Lymph Node Metastasis.
Li L, Wang Z, Lu T, Li Y, Pan M, Yu D, Hu G
OncoTargets and therapy 2021;14:1387-1399
OncoTargets and therapy 2021;14:1387-1399
Circular RNA ERBB2 Contributes to Proliferation and Migration of Airway Smooth Muscle Cells via miR-98-5p/IGF1R Signaling in Asthma.
Huang JQ, Wang F, Wang LT, Li YM, Lu JL, Chen JY
Journal of asthma and allergy 2021;14:1197-1207
Journal of asthma and allergy 2021;14:1197-1207
FUT7 Promotes the Epithelial-Mesenchymal Transition and Immune Infiltration in Bladder Urothelial Carcinoma.
Liu M, Zheng Q, Chen S, Liu J, Li S
Journal of inflammation research 2021;14:1069-1084
Journal of inflammation research 2021;14:1069-1084
The cardioprotective effect of the sodium-glucose cotransporter 2 inhibitor dapagliflozin in rats with isoproterenol-induced cardiomyopathy.
Wang FZ, Wei WB, Li X, Huo JY, Jiang WY, Wang HY, Qian P, Li ZZ, Zhou YB
American journal of translational research 2021;13(9):10950-10961
American journal of translational research 2021;13(9):10950-10961
Knockdown of VDAC1 alleviates the cognitive dysfunction secondary to sepsis-associated encephalopathy.
Cai M, Du B, Si Y, Miao J, Ge J, Zhang J, Song J, Bao H
American journal of translational research 2021;13(7):7538-7555
American journal of translational research 2021;13(7):7538-7555
Qi Ling decoction reduces gastric cancer cell metastasis by inhibiting MMP-9 through the PI3K/Akt signaling pathway.
Chen W, Zhang Y, Gu X, Qian P, Liu W, Shu P
American journal of translational research 2021;13(5):4591-4602
American journal of translational research 2021;13(5):4591-4602
Inhibition of mu-opioid receptor suppresses proliferation of hepatocellular carcinoma cells via CD147-p53-MAPK cascade signaling pathway.
Zhang JJ, Song CG, Dai JM, Zhang XQ, Lin P, Li L, Yang XM, Chen ZN
American journal of translational research 2021;13(5):3967-3986
American journal of translational research 2021;13(5):3967-3986
Positive Feedback Loop of Long Noncoding RNA OASL-IT1 and Innate Immune Response Restricts the Replication of Zika Virus in Epithelial A549 Cells.
Wang Y, Huo Z, Lin Q, Lin Y, Chen C, Huang Y, Huang C, Zhang J, He J, Liu C, Zhang P
Journal of innate immunity 2021;13(3):179-193
Journal of innate immunity 2021;13(3):179-193
Curcumin promotes the survival of ischemic random skin flaps via autophagy.
Tu Z, Jiang X, Li Y, Yang S, Lin D, Shi Y, Mao C, Zhang X, Lin C
American journal of translational research 2021;13(3):1337-1351
American journal of translational research 2021;13(3):1337-1351
TET2 mediated demethylation is involved in the protective effect of triptolide on podocytes.
Wan F, Tang YW, Tang XL, Li YY, Yang RC
American journal of translational research 2021;13(3):1233-1244
American journal of translational research 2021;13(3):1233-1244
Comparative analysis identifies significant peptides related to asthma mechanism.
Zhu D, Wang C, Meng C, Liu Y, Zeng Z, Zhao R, Dong X, Wang X
American journal of translational research 2021;13(12):13471-13484
American journal of translational research 2021;13(12):13471-13484
Distinct effects of ANGPT2 on gene expression of glomerular podocytes and mesangial cells.
Ren L, Zhang S, Shi J, Wang X, Qin W, Liu Z, Shi S
American journal of translational research 2021;13(11):12249-12263
American journal of translational research 2021;13(11):12249-12263
Sevoflurane prevents pulmonary vascular remodeling and right ventricular dysfunction in pulmonary arterial hypertension in rats.
Zhai W, Li Y, Luo Y, Gao W, Liu S, Han J, Geng J
American journal of translational research 2021;13(10):11302-11315
American journal of translational research 2021;13(10):11302-11315
Dura cells in the etiopathogenesis of Crouzon syndrome: the effects of FGFR2 mutations in the dura cells on the proliferation of osteoblasts through the hippo/YAP mediated transcriptional regulation pathway.
Dong XH, Zhang MZ, Lai CZ, Li CC, Du L, Song GD, Zong XL, Jin XL
American journal of translational research 2021;13(10):11255-11270
American journal of translational research 2021;13(10):11255-11270
Combination effect of curcumin with docetaxel on the PI3K/AKT/mTOR pathway to induce autophagy and apoptosis in esophageal squamous cell carcinoma.
Deng L, Wu X, Zhu X, Yu Z, Liu Z, Wang J, Zheng Y
American journal of translational research 2021;13(1):57-72
American journal of translational research 2021;13(1):57-72
Downregulation of miRNA-451a Promotes the Differentiation of CD4+ T Cells towards Th2 Cells by Upregulating ETS1 in Childhood Asthma.
Wang T, Zhou Q, Shang Y
Journal of innate immunity 2021;13(1):38-48
Journal of innate immunity 2021;13(1):38-48
PARK2 attenuates house dust mite-induced inflammatory reaction, pyroptosis and barrier dysfunction in BEAS-2B cells by ubiquitinating NLRP3.
Ge X, Cai F, Shang Y, Chi F, Xiao H, Xu J, Fu Y, Bai C
American journal of translational research 2021;13(1):326-335
American journal of translational research 2021;13(1):326-335
The Circadian Gene NPAS2 Act as a Putative Tumor Stimulative Factor for Uterine Corpus Endometrial Carcinoma.
Zheng X, Lv X, Zhu L, Xu K, Shi C, Cui L, Ding H
Cancer management and research 2021;13:9329-9343
Cancer management and research 2021;13:9329-9343
BBOX1-AS1 Accelerates Nasopharyngeal Carcinoma Progression by Sponging miR-3940-3p and Enhancing KPNA2 Upregulation.
Jiang H, He Q, Liu T
Cancer management and research 2021;13:9049-9062
Cancer management and research 2021;13:9049-9062
LncRNA FOXD3-AS1 Promotes Tumorigenesis of Glioma via Targeting miR-128-3p/SZRD1 Axis.
Li Z, Li M, Xia P, Wang L, Lu Z
Cancer management and research 2021;13:9037-9048
Cancer management and research 2021;13:9037-9048
AGTR1 Inhibits the Progression of Lung Adenocarcinoma.
Xiong L, Wei Y, Zhou X, Dai P, Cai Y, Zhou X, Xu M, Zhao J, Tang H
Cancer management and research 2021;13:8535-8550
Cancer management and research 2021;13:8535-8550
lncRNA AC007207.2 Promotes Malignant Properties of Osteosarcoma via the miR-1306-5p/SIRT7 Axis.
Dang Y, Zhou Y, Ou X, Wang Q, Wei D, Xie F
Cancer management and research 2021;13:7277-7288
Cancer management and research 2021;13:7277-7288
Stress Granules Modulate SYK to Cause Tau-Associated Neurocognitive Deterioration in 5XFAD Mouse After Anesthesia and Surgery.
Shen Y, Zhang T, Zhang Y, Wang Y, Yao J
Frontiers in aging neuroscience 2021;13:718701
Frontiers in aging neuroscience 2021;13:718701
Enriched Environment Attenuates Pyroptosis to Improve Functional Recovery After Cerebral Ischemia/Reperfusion Injury.
Liu J, Zheng J, Xu Y, Cao W, Wang J, Wang B, Zhao L, Zhang X, Liao W
Frontiers in aging neuroscience 2021;13:717644
Frontiers in aging neuroscience 2021;13:717644
MALAT-1 is Associated with the Doxorubicin Resistance in U-2OS Osteosarcoma Cells.
Liu C, Han X, Li B, Huang S, Zhou Z, Wang Z, Wang W
Cancer management and research 2021;13:6879-6889
Cancer management and research 2021;13:6879-6889
Calcitriol Alleviates MPP(+)- and MPTP-Induced Parthanatos Through the VDR/PARP1 Pathway in the Model of Parkinson's Disease.
Hu J, Wu J, Wan F, Kou L, Yin S, Sun Y, Li Y, Zhou Q, Wang T
Frontiers in aging neuroscience 2021;13:657095
Frontiers in aging neuroscience 2021;13:657095
Intranasal Transplantation of Human Neural Stem Cells Ameliorates Alzheimer's Disease-Like Pathology in a Mouse Model.
Lu MH, Ji WL, Chen H, Sun YY, Zhao XY, Wang F, Shi Y, Hu YN, Liu BX, Wu JW, Xu DE, Zheng JW, Liu CF, Ma QH
Frontiers in aging neuroscience 2021;13:650103
Frontiers in aging neuroscience 2021;13:650103
Long-Term Administration of Triterpenoids From Ganoderma lucidum Mitigates Age-Associated Brain Physiological Decline via Regulating Sphingolipid Metabolism and Enhancing Autophagy in Mice.
Zeng M, Qi L, Guo Y, Zhu X, Tang X, Yong T, Xie Y, Wu Q, Zhang M, Chen D
Frontiers in aging neuroscience 2021;13:628860
Frontiers in aging neuroscience 2021;13:628860
The Non-peptide Angiotensin-(1-7) Mimic AVE 0991 Attenuates Delayed Neurocognitive Recovery After Laparotomy by Reducing Neuroinflammation and Restoring Blood-Brain Barrier Integrity in Aged Rats.
Mi X, Cao Y, Li Y, Li Y, Hong J, He J, Liang Y, Yang N, Liu T, Han D, Kuang C, Han Y, Zhou Y, Liu Y, Shi C, Guo X, Li Z
Frontiers in aging neuroscience 2021;13:624387
Frontiers in aging neuroscience 2021;13:624387
Plakophilin-2 Promotes Lung Adenocarcinoma Development via Enhancing Focal Adhesion and Epithelial-Mesenchymal Transition.
Wu Y, Liu L, Shen X, Liu W, Ma R
Cancer management and research 2021;13:559-570
Cancer management and research 2021;13:559-570
KLF7 Promotes Gastric Carcinogenesis Through Regulation of ANTXR1.
Li Y, Wang Q, Wang D, Fu W
Cancer management and research 2021;13:5547-5557
Cancer management and research 2021;13:5547-5557
Columbamine-Mediated PTEN/AKT Signal Pathway Regulates the Progression of Glioma.
Niu HT, Liu Y, Wang YZ, Tian Y, Yang M, Jiang HS
Cancer management and research 2021;13:489-497
Cancer management and research 2021;13:489-497
The Preliminary Study for Postoperative Radiotherapy Survival Associated with RUNX3 and TLR9 Expression in Lung Cancer.
Gao C, Qiao T, Yuan S, Zhuang X
Cancer management and research 2021;13:4497-4507
Cancer management and research 2021;13:4497-4507
Overexpression of Taspase 1 Predicts Poor Prognosis in Patients with Hepatocellular Carcinoma.
Jiang J, Liu B, Liu R, Yang W
Cancer management and research 2021;13:2517-2537
Cancer management and research 2021;13:2517-2537
Identification of TRIM56 as a Potential Biomarker for Lung Adenocarcinoma.
Lu K, Sui Y, Fu L
Cancer management and research 2021;13:2201-2213
Cancer management and research 2021;13:2201-2213
Identification and validation of the clinical roles of the VHL-related LncRNAs in clear cell renal cell carcinoma.
Yang W, Zhou J, Zhang K, Li L, Xu Y, Ma K, Xie H, Cai L, Gong Y, Gong K
Journal of Cancer 2021;12(9):2702-2714
Journal of Cancer 2021;12(9):2702-2714
SCARA5 inhibits gastric cancer progression via epithelial-mesenchymal transition suppression.
Zhang H, Liu C, Wang X, Wang Y, Zheng J
Journal of Cancer 2021;12(8):2412-2421
Journal of Cancer 2021;12(8):2412-2421
Peri-tumoral brain edema associated with glioblastoma correlates with tumor recurrence.
Qin X, Liu R, Akter F, Qin L, Xie Q, Li Y, Qiao H, Zhao W, Jian Z, Liu R, Wu S
Journal of Cancer 2021;12(7):2073-2082
Journal of Cancer 2021;12(7):2073-2082
Long non-coding RNA SNHG25 promotes epithelial ovarian cancer progression by up-regulating COMP.
Liu Y, Xu B, Liu M, Qiao H, Zhang S, Qiu J, Ying X
Journal of Cancer 2021;12(6):1660-1668
Journal of Cancer 2021;12(6):1660-1668
Elevated expression of Tweety homologue 3 predicts poor clinical outcomes in ovarian cancer.
Zhou J, Xu Y, Chen X, Chen F, Zhang J, Zhu X
Journal of Cancer 2021;12(23):7147-7157
Journal of Cancer 2021;12(23):7147-7157
N6-methyladenosine regulates ATM expression and downstream signaling.
Zhang X, Liu P, Zheng X, Wang J, Peng Q, Li Z, Wei L, Liu C, Wu Y, Wen Y, Yan Q, Ma J
Journal of Cancer 2021;12(23):7041-7051
Journal of Cancer 2021;12(23):7041-7051
Decreased interferon regulatory factor 6 expression due to DNA hypermethylation predicts an unfavorable prognosis in clear cell renal cell carcinoma.
Li Z, Yang W, Qiu J, Xu H, Fan B, Li K, Zhou J, Li Y
Journal of Cancer 2021;12(22):6640-6655
Journal of Cancer 2021;12(22):6640-6655
FGF14-AS2 accelerates tumorigenesis in glioma by forming a feedback loop with miR-320a/E2F1 axis.
Zhang P, Gu X, Zhang N, Liu L, Dong X, Li H, Cheng S, Li S, Yuan J, Li Y, Dong J
Journal of Cancer 2021;12(21):6429-6438
Journal of Cancer 2021;12(21):6429-6438
RUNX1 regulates the proliferation and chemoresistance of colorectal cancer through the Hedgehog signaling pathway.
Li Q, Lai Q, He C, Zhang H, Pan X, Li H, Yan Q, Fang Y, Liu S, Li A
Journal of Cancer 2021;12(21):6363-6371
Journal of Cancer 2021;12(21):6363-6371
Effect of EG00229 on Radiation Resistance of Lung Adenocarcinoma Cells.
Cong L, Yi J, Qiu S, Wang R, Jin S, Jiang R, Cong X
Journal of Cancer 2021;12(20):6105-6117
Journal of Cancer 2021;12(20):6105-6117
miR-552 promotes the proliferation and metastasis of cervical cancer cells through targeting MUC15 pathway.
Zhang X, Zhang Y, Dou L
Journal of Cancer 2021;12(20):6094-6104
Journal of Cancer 2021;12(20):6094-6104
Lipid Storage and Interferon Response Determine the Phenotype of Ground Glass Hepatocytes in Mice and Humans.
Churin Y, Irungbam K, Imiela CS, Schwarz D, Mollenkopf HJ, Drebber U, Odenthal M, Pak O, Huber M, Glebe D, Roderfeld M, Roeb E
Cellular and molecular gastroenterology and hepatology 2021;12(2):383-394
Cellular and molecular gastroenterology and hepatology 2021;12(2):383-394
Co-overexpression of RIOK1 and AKT1 as a prognostic risk factor in glioma.
Wang Y, Xie X, Li S, Zhang D, Zheng H, Zhang M, Zhang Z
Journal of Cancer 2021;12(19):5745-5752
Journal of Cancer 2021;12(19):5745-5752
MRPS17 promotes invasion and metastasis through PI3K/AKT signal pathway and could be potential prognostic marker for gastric cancer.
Zhou W, Ouyang J, Li J, Liu F, An T, Cheng L, Kuo ZC, Zhang C, He Y
Journal of Cancer 2021;12(16):4849-4861
Journal of Cancer 2021;12(16):4849-4861
EIF5A expression and its role as a potential diagnostic biomarker in hepatocellular carcinoma.
Li L, Li X, Zhang Q, Ye T, Zou S, Yan J
Journal of Cancer 2021;12(16):4774-4779
Journal of Cancer 2021;12(16):4774-4779
Demethylzelasteral inhibits proliferation and EMT via repressing Wnt/β-catenin signaling in esophageal squamous cell carcinoma.
Yu J, Wang W, Liu B, Gu J, Chen S, Cui Y, Sun G
Journal of Cancer 2021;12(13):3967-3975
Journal of Cancer 2021;12(13):3967-3975
Diosgenin From Dioscorea Nipponica Rhizoma Against Graves' Disease-On Network Pharmacology and Experimental Evaluation.
Xin J, Cheng W, Yu Y, Chen J, Zhang X, Shao S
Frontiers in pharmacology 2021;12:806829
Frontiers in pharmacology 2021;12:806829
Biphasic Effect of Pirfenidone on Angiogenesis.
Gan D, Cheng W, Ke L, Sun AR, Jia Q, Chen J, Xu Z, Xu J, Zhang P
Frontiers in pharmacology 2021;12:804327
Frontiers in pharmacology 2021;12:804327
PTRF/Cavin-1 as a Novel RNA-Binding Protein Expedites the NF-κB/PD-L1 Axis by Stabilizing lncRNA NEAT1, Contributing to Tumorigenesis and Immune Evasion in Glioblastoma.
Yi K, Cui X, Liu X, Wang Y, Zhao J, Yang S, Xu C, Yang E, Xiao M, Hong B, Fang C, Kang C, Tan Y, Wang Q
Frontiers in immunology 2021;12:802795
Frontiers in immunology 2021;12:802795
Galectin-9/TIM-3 as a Key Regulator of Immune Response in Gliomas With Chromosome 1p/19q Codeletion.
Li G, Huang R, Fan W, Wang D, Wu F, Zeng F, Yu M, Zhai Y, Chang Y, Pan C, Jiang T, Yan W, Wang H, Zhang W
Frontiers in immunology 2021;12:800928
Frontiers in immunology 2021;12:800928
Myricanol Inhibits Platelet Derived Growth Factor-BB-Induced Vascular Smooth Muscle Cells Proliferation and Migration in vitro and Intimal Hyperplasia in vivo by Targeting the Platelet-Derived Growth Factor Receptor-β and NF-κB Signaling.
Fan S, Wang C, Huang K, Liang M
Frontiers in physiology 2021;12:790345
Frontiers in physiology 2021;12:790345
Hsa-miR-557 Inhibits Osteosarcoma Growth Through Targeting KRAS.
Qiao Z, Li J, Kou H, Chen X, Bao D, Shang G, Chen S, Ji Y, Cheng T, Wang Y, Liu H
Frontiers in genetics 2021;12:789823
Frontiers in genetics 2021;12:789823
HSP27 Protein Dampens Encephalomyocarditis Virus Replication by Stabilizing Melanoma Differentiation-Associated Gene 5.
Li X, Ma R, Wu B, Niu Y, Li H, Li D, Xie J, Idris A, Feng R
Frontiers in microbiology 2021;12:788870
Frontiers in microbiology 2021;12:788870
Exercise Capacity Is Improved by Levosimendan in Heart Failure and Sarcopenia via Alleviation of Apoptosis of Skeletal Muscle.
Wang D, Song M, Shen LF, Han L, Zhu P, Jia X, Shang GK, Cao Y, Zhang W, Zhong M, Wang ZH
Frontiers in physiology 2021;12:786895
Frontiers in physiology 2021;12:786895
Altered Expression of Par3, aPKC-λ, and Lgl1 in Hippocampus in Kainic Acid-Induced Status Epilepticus Rat Model.
Zhang C, Tian F, Tan Z, Du J, Long X
Frontiers in neurology 2021;12:780042
Frontiers in neurology 2021;12:780042
FBXO22 Promotes Growth and Metastasis and Inhibits Autophagy in Epithelial Ovarian Cancers via the MAPK/ERK Pathway.
Li M, Zhao X, Yong H, Shang B, Lou W, Wang Y, Bai J
Frontiers in pharmacology 2021;12:778698
Frontiers in pharmacology 2021;12:778698
Cardiac Effects of Treadmill Running at Different Intensities in a Rat Model.
Yan Z, Zeng N, Li J, Liao T, Ni G
Frontiers in physiology 2021;12:774681
Frontiers in physiology 2021;12:774681
Autophagy Induced by Micheliolide Alleviates Acute Irradiation-Induced Intestinal Injury via Inhibition of the NLRP3 Inflammasome.
Wu DM, Li J, Shen R, Li J, Yu Y, Li L, Deng SH, Liu T, Zhang T, Xu Y, Wang DG
Frontiers in pharmacology 2021;12:773150
Frontiers in pharmacology 2021;12:773150
BCI Suppresses RANKL-Mediated Osteoclastogenesis and Alleviates Ovariectomy-Induced Bone Loss.
Cai C, Hu W, Zhang Y, Hu X, Yang S, Qiu H, Wang R, Ma M, Qiu Y, Chu T
Frontiers in pharmacology 2021;12:772540
Frontiers in pharmacology 2021;12:772540
Histone H2A Nuclear/Cytoplasmic Trafficking Is Essential for Negative Regulation of Antiviral Immune Response and Lysosomal Degradation of TBK1 and IRF3.
Wu XM, Fang H, Zhang J, Bi YH, Chang MX
Frontiers in immunology 2021;12:771277
Frontiers in immunology 2021;12:771277
SOAT1 Promotes Gastric Cancer Lymph Node Metastasis Through Lipid Synthesis.
Zhu T, Wang Z, Zou T, Xu L, Zhang S, Chen Y, Chen C, Zhang W, Wang S, Ding Q, Xu G
Frontiers in pharmacology 2021;12:769647
Frontiers in pharmacology 2021;12:769647
PARP Inhibitor Upregulates PD-L1 Expression and Provides a New Combination Therapy in Pancreatic Cancer.
Wang Y, Zheng K, Xiong H, Huang Y, Chen X, Zhou Y, Qin W, Su J, Chen R, Qiu H, Yuan X, Wang Y, Zou Y
Frontiers in immunology 2021;12:762989
Frontiers in immunology 2021;12:762989
Physalin A Inhibits MAPK and NF-κB Signal Transduction Through Integrin αVβ3 and Exerts Chondroprotective Effect.
Lu R, Yu X, Liang S, Cheng P, Wang Z, He ZY, Lv ZT, Wan J, Mo H, Zhu WT, Chen AM
Frontiers in pharmacology 2021;12:761922
Frontiers in pharmacology 2021;12:761922
Activation of 1-Aminocyclopropane-1-Carboxylic Acid Synthases Sets Stomatal Density and Clustered Ratio on Leaf Epidermis of Arabidopsis in Response to Drought.
Jia MZ, Liu LY, Geng C, Jiang J
Frontiers in plant science 2021;12:758785
Frontiers in plant science 2021;12:758785
Characterization of Pathogenesis and Inflammatory Responses to Experimental Parechovirus Encephalitis.
Jan MW, Su HL, Chang TH, Tsai KJ
Frontiers in immunology 2021;12:753683
Frontiers in immunology 2021;12:753683
Duhaldea pterocaula (Franch.) Anderb. Attenuates Nociception and Inflammation via GABA(A) Receptors.
Huang C, Dong C, Zhu Y, Yu Y, Jin H, Zhang Y
Frontiers in pharmacology 2021;12:753128
Frontiers in pharmacology 2021;12:753128
Nox4 Promotes RANKL-Induced Autophagy and Osteoclastogenesis via Activating ROS/PERK/eIF-2α/ATF4 Pathway.
Sun J, Chen W, Li S, Yang S, Zhang Y, Hu X, Qiu H, Wu J, Xu S, Chu T
Frontiers in pharmacology 2021;12:751845
Frontiers in pharmacology 2021;12:751845
Chinese Herbal Preparation SaiLuoTong Alleviates Brain Ischemia via Nrf2 Antioxidation Pathway-Dependent Cerebral Microvascular Protection.
Fan XD, Yao MJ, Yang B, Han X, Zhang YH, Wang GR, Li P, Xu L, Liu JX
Frontiers in pharmacology 2021;12:748568
Frontiers in pharmacology 2021;12:748568
An Integrative Pharmacology Based Analysis of Refined Liuweiwuling Against Liver Injury: A Novel Component Combination and Hepaprotective Mechanism.
Gao Y, Shi W, Yao H, Ai Y, Li R, Wang Z, Liu T, Dai W, Xiao X, Zhao J, Niu M, Bai Z
Frontiers in pharmacology 2021;12:747010
Frontiers in pharmacology 2021;12:747010
Naringenin Regulates FKBP4/NR3C1/NRF2 Axis in Autophagy and Proliferation of Breast Cancer and Differentiation and Maturation of Dendritic Cell.
Xiong H, Chen Z, Lin B, Xie B, Liu X, Chen C, Li Z, Jia Y, Wu Z, Yang M, Jia Y, Wang L, Zhou J, Meng X
Frontiers in immunology 2021;12:745111
Frontiers in immunology 2021;12:745111
Micronized Palmitoylethanolamide Ameliorates Methionine- and Choline-Deficient Diet-Induced Nonalcoholic Steatohepatitis via Inhibiting Inflammation and Restoring Autophagy.
Hu J, Ying H, Yao J, Yang L, Jin W, Ma H, Li L, Zhao Y
Frontiers in pharmacology 2021;12:744483
Frontiers in pharmacology 2021;12:744483
Disease-Modifying Anti-rheumatic Drug Prescription Baihu-Guizhi Decoction Attenuates Rheumatoid Arthritis via Suppressing Toll-Like Receptor 4-mediated NLRP3 Inflammasome Activation.
Li W, Mao X, Wang X, Liu Y, Wang K, Li C, Li T, Zhang Y, Lin N
Frontiers in pharmacology 2021;12:743086
Frontiers in pharmacology 2021;12:743086
Remimazolam Protects Against LPS-Induced Endotoxicity Improving Survival of Endotoxemia Mice.
Liu X, Lin S, Zhong Y, Shen J, Zhang X, Luo S, Huang L, Zhang L, Zhou S, Tang J
Frontiers in pharmacology 2021;12:739603
Frontiers in pharmacology 2021;12:739603
Clostridium butyricum Supplement Can Ameliorate the Intestinal Barrier Roles in Broiler Chickens Experimentally Infected With Clostridium perfringens.
Xu X, Yang S, Olajide JS, Qu Z, Gong Z, Wang J, Zhang Y, Wang H, Xiong L, Zhang K, Zhou E, Cai J
Frontiers in physiology 2021;12:737481
Frontiers in physiology 2021;12:737481
Screening of a Small Molecule Compound Library Identifies Toosendanin as an Inhibitor Against Bunyavirus and SARS-CoV-2.
Li S, Ye M, Chen Y, Zhang Y, Li J, Liu W, Li H, Peng K
Frontiers in pharmacology 2021;12:735223
Frontiers in pharmacology 2021;12:735223
Activation of Yes-Associated Protein/PDZ-Binding Motif Pathway Contributes to Endothelial Dysfunction and Vascular Inflammation in AngiotensinII Hypertension.
Xu Q, Zhuo K, Cai R, Su X, Zhang L, Liu Y, Zhu L, Ren F, Zhou MS
Frontiers in physiology 2021;12:732084
Frontiers in physiology 2021;12:732084
Selective STAT3 Inhibitor Alantolactone Ameliorates Osteoarthritis via Regulating Chondrocyte Autophagy and Cartilage Homeostasis.
Pei W, Huang X, Ni B, Zhang R, Niu G, You H
Frontiers in pharmacology 2021;12:730312
Frontiers in pharmacology 2021;12:730312
Fascin-1 is Highly Expressed Specifically in Microglia After Spinal Cord Injury and Regulates Microglial Migration.
Yu S, Cheng L, Tian D, Li Z, Yao F, Luo Y, Liu Y, Zhu Z, Zheng M, Jing J
Frontiers in pharmacology 2021;12:729524
Frontiers in pharmacology 2021;12:729524
VDR Signaling via the Enzyme NAT2 Inhibits Colorectal Cancer Progression.
Zhu C, Wang Z, Cai J, Pan C, Lin S, Zhang Y, Chen Y, Leng M, He C, Zhou P, Wu C, Fang Y, Li Q, Li A, Liu S, Lai Q
Frontiers in pharmacology 2021;12:727704
Frontiers in pharmacology 2021;12:727704
Samotolisib Attenuates Acute Liver Injury Through Inhibiting Caspase-11-Mediated Pyroptosis Via Regulating E3 Ubiquitin Ligase Nedd4.
Zhao YY, Wu DM, He M, Zhang F, Zhang T, Liu T, Li J, Li L, Xu Y
Frontiers in pharmacology 2021;12:726198
Frontiers in pharmacology 2021;12:726198
Huangqi Shengmai Yin Ameliorates Myocardial Fibrosis by Activating Sirtuin3 and Inhibiting TGF-β/Smad Pathway.
Pan J, Cao Z, Fang C, Lei Y, Sun J, Huang X, Han D
Frontiers in pharmacology 2021;12:722530
Frontiers in pharmacology 2021;12:722530
Extracellular CIRP Induces an Inflammatory Phenotype in Pulmonary Fibroblasts via TLR4.
Bolourani S, Sari E, Brenner M, Wang P
Frontiers in immunology 2021;12:721970
Frontiers in immunology 2021;12:721970
ZnT8 Deficiency Protects From APAP-Induced Acute Liver Injury by Reducing Oxidative Stress Through Upregulating Hepatic Zinc and Metallothioneins.
Su W, Feng M, Liu Y, Cao R, Liu Y, Tang J, Pan K, Lan R, Mao Z
Frontiers in pharmacology 2021;12:721471
Frontiers in pharmacology 2021;12:721471
Identification of a Novel Epigenetic Signature CHFR as a Potential Prognostic Gene Involved in Metastatic Clear Cell Renal Cell Carcinoma.
Chen X, Lin J, Chen Q, Liao X, Wang T, Li S, Mao L, Li Z
Frontiers in genetics 2021;12:720979
Frontiers in genetics 2021;12:720979
EGFR-IL-6 Signaling Axis Mediated the Inhibitory Effect of Methylseleninic Acid on Esophageal Squamous Cell Carcinoma.
Wang Y, Liu X, Hu G, Hu C, Gao Y, Huo M, Zhu H, Liu M, Xu N
Frontiers in pharmacology 2021;12:719785
Frontiers in pharmacology 2021;12:719785
Combined Administration of Vitamin D(3) and Geniposide Is Less Effective than Single Use of Vitamin D(3) or Geniposide in the Treatment of Ulcerative Colitis.
Lu Y, Chen J, He X, Xu S, Chen YE, Gao J, Hou S
Frontiers in pharmacology 2021;12:714065
Frontiers in pharmacology 2021;12:714065
Mefunidone Ameliorates Bleomycin-Induced Pulmonary Fibrosis in Mice.
Han Y, Jiang M, He R, Lv X, Liao X, He Y, Zhang F, Long L, Jiang G, Peng Z, Tao L, Hu G, Meng J
Frontiers in pharmacology 2021;12:713572
Frontiers in pharmacology 2021;12:713572
Sinensetin Reduces Osteoarthritis Pathology in the Tert-Butyl Hydroperoxide-Treated Chondrocytes and the Destabilization of the Medial Meniscus Model Mice via the AMPK/mTOR Signaling Pathway.
Zhou W, Shi Y, Wang H, Yu C, Zhu H, Wu A
Frontiers in pharmacology 2021;12:713491
Frontiers in pharmacology 2021;12:713491
Azithromycin Attenuates Bleomycin-Induced Pulmonary Fibrosis Partly by Inhibiting the Expression of LOX and LOXL-2.
Tong X, Zhang S, Wang D, Zhang L, Huang J, Zhang T, Fan H
Frontiers in pharmacology 2021;12:709819
Frontiers in pharmacology 2021;12:709819
Novel Molecule Nell-1 Promotes the Angiogenic Differentiation of Dental Pulp Stem Cells.
Li M, Wang Q, Han Q, Wu J, Zhu H, Fang Y, Bi X, Chen Y, Yao C, Wang X
Frontiers in physiology 2021;12:703593
Frontiers in physiology 2021;12:703593
Preexposure and Postexposure Prophylaxis of Rabies With Adeno-Associated Virus Expressing Virus-Neutralizing Antibody in Rodent Models.
Huang F, Ren M, Pei J, Mei H, Sui B, Wu Q, Chai B, Yang R, Zhou M, Fu ZF, Zhou H, Zhao L
Frontiers in microbiology 2021;12:702273
Frontiers in microbiology 2021;12:702273
RPL22 Overexpression Promotes Psoriasis-Like Lesion by Inducing Keratinocytes Abnormal Biological Behavior.
Zeng J, Zhang Y, Zhang H, Zhang Y, Gao L, Tong X, Xie Y, Hu Q, Chen C, Ding S, Lu J
Frontiers in immunology 2021;12:699900
Frontiers in immunology 2021;12:699900
Screening and Identification of Key Genes for Activation of Islet Stellate Cell.
Wang X, Carvalho V, Wang Q, Wang J, Li T, Chen Y, Ni C, Liu L, Yuan Y, Qiu S, Sun Z
Frontiers in endocrinology 2021;12:695467
Frontiers in endocrinology 2021;12:695467
Characterization of the Potential Role of NTPCR in Epithelial Ovarian Cancer by Integrating Transcriptomic and Metabolomic Analysis.
Shang H, Zhang H, Ren Z, Zhao H, Zhang Z, Tong J
Frontiers in genetics 2021;12:695245
Frontiers in genetics 2021;12:695245
Preclinical Investigation of Alpinetin in the Treatment of Cancer-Induced Cachexia via Activating PPARγ.
Zhang Y, Zhang Y, Li Y, Zhang L, Yu S
Frontiers in pharmacology 2021;12:687491
Frontiers in pharmacology 2021;12:687491
Overexpression of SHMT2 Predicts a Poor Prognosis and Promotes Tumor Cell Growth in Bladder Cancer.
Zhang P, Yang Q
Frontiers in genetics 2021;12:682856
Frontiers in genetics 2021;12:682856
Loganin Inhibits Angiotensin II-Induced Cardiac Hypertrophy Through the JAK2/STAT3 and NF-κB Signaling Pathways.
Xu JJ, Li RJ, Zhang ZH, Yang C, Liu SX, Li YL, Chen MW, Wang WW, Zhang GY, Song G, Huang ZR
Frontiers in pharmacology 2021;12:678886
Frontiers in pharmacology 2021;12:678886
Traditional Chinese Medication Tongxinluo Attenuates Lipidosis in Ox-LDL-Stimulated Macrophages by Enhancing Beclin-1-Induced Autophagy.
Chen Y, Yu F, Zhang Y, Li M, Di M, Chen W, Liu X, Zhang Y, Zhang M
Frontiers in pharmacology 2021;12:673366
Frontiers in pharmacology 2021;12:673366
SEC23A Is an Independent Prognostic Biomarker in Bladder Cancer Correlated With MAPK Signaling.
Zeng B, Zhao Q, Sun Z, Liu D, Chen H, Li X, Wang J, Xing HR
Frontiers in genetics 2021;12:672832
Frontiers in genetics 2021;12:672832
Pig Liver Esterases Hydrolyze Endocannabinoids and Promote Inflammatory Response.
Zhou Q, Yan B, Sun W, Chen Q, Xiao Q, Xiao Y, Wang X, Shi D
Frontiers in immunology 2021;12:670427
Frontiers in immunology 2021;12:670427
Feasibility and Mechanism Analysis of Shenfu Injection in the Treatment of Idiopathic Pulmonary Fibrosis.
Liu P, Yang S, Wang Z, Dai H, Wang C
Frontiers in pharmacology 2021;12:670146
Frontiers in pharmacology 2021;12:670146
M2a Macrophage-Secreted CHI3L1 Promotes Extracellular Matrix Metabolic Imbalances via Activation of IL-13Rα2/MAPK Pathway in Rat Intervertebral Disc Degeneration.
Li L, Wei K, Ding Y, Ahati P, Xu H, Fang H, Wang H
Frontiers in immunology 2021;12:666361
Frontiers in immunology 2021;12:666361
Atractylodin Attenuates Dextran Sulfate Sodium-Induced Colitis by Alleviating Gut Microbiota Dysbiosis and Inhibiting Inflammatory Response Through the MAPK Pathway.
Qu L, Lin X, Liu C, Ke C, Zhou Z, Xu K, Cao G, Liu Y
Frontiers in pharmacology 2021;12:665376
Frontiers in pharmacology 2021;12:665376
A Novel Loss-of-Function MKRN3 Variant in a Chinese Patient With Familial Precocious Puberty: A Case Report and Functional Study.
Yin X, Wang J, Han T, Tingting Z, Li Y, Dong Z, Wang W, Li C, Lu W
Frontiers in genetics 2021;12:663746
Frontiers in genetics 2021;12:663746
STAT3-Dependent Gene TRIM5γ Interacts With HBx Through a Zinc Binding Site on the BBox Domain.
Song H, Xu F, Pang X, Xiao Q, Wei Q, Lei B, Li X, Fan X, Tan G
Frontiers in microbiology 2021;12:663534
Frontiers in microbiology 2021;12:663534
Lipidomics Revealed Alteration of Sphingolipid Metabolism During the Reparative Phase After Myocardial Infarction Injury.
Hua T, Bao Q, He X, Cai W, He J
Frontiers in physiology 2021;12:663480
Frontiers in physiology 2021;12:663480
SARS-CoV-2 Membrane Protein Inhibits Type I Interferon Production Through Ubiquitin-Mediated Degradation of TBK1.
Sui L, Zhao Y, Wang W, Wu P, Wang Z, Yu Y, Hou Z, Tan G, Liu Q
Frontiers in immunology 2021;12:662989
Frontiers in immunology 2021;12:662989
Targeting Glycogen Synthase Kinase 3 Beta Regulates CD47 Expression After Myocardial Infarction in Rats via the NF-κB Signaling Pathway.
Xu LN, Wang SH, Su XL, Komal S, Fan HK, Xia L, Zhang LR, Han SN
Frontiers in pharmacology 2021;12:662726
Frontiers in pharmacology 2021;12:662726
Characterization of Two Loss-of-Function NF1 Variants in Chinese Patients and Potential Molecular Interpretations of Phenotypes.
Zhang T, Han T, Dong Z, Li C, Lu W
Frontiers in genetics 2021;12:660592
Frontiers in genetics 2021;12:660592
DsbA-L Ameliorates Renal Injury Through the AMPK/NLRP3 Inflammasome Signaling Pathway in Diabetic Nephropathy.
Yang M, Luo S, Jiang N, Wang X, Han Y, Zhao H, Xiong X, Liu Y, Zhao C, Zhu X, Sun L
Frontiers in physiology 2021;12:659751
Frontiers in physiology 2021;12:659751
The New PI3K/mTOR Inhibitor GNE-477 Inhibits the Malignant Behavior of Human Glioblastoma Cells.
Wang Y, Shen H, Sun Q, Zhao L, Liu H, Ye L, Xu Y, Cai J, Li Y, Gao L, Tan Y, Liu B, Chen Q
Frontiers in pharmacology 2021;12:659511
Frontiers in pharmacology 2021;12:659511
Effect of Protein O-Mannosyltransferase (MSMEG_5447) on M. smegmatis and Its Survival in Macrophages.
Jia L, Sha S, Yang S, Taj A, Ma Y
Frontiers in microbiology 2021;12:657726
Frontiers in microbiology 2021;12:657726
Pulmonary Artery Smooth Muscle Cell Senescence Promotes the Proliferation of PASMCs by Paracrine IL-6 in Hypoxia-Induced Pulmonary Hypertension.
Wang AP, Yang F, Tian Y, Su JH, Gu Q, Chen W, Gong SX, Ma XF, Qin XP, Jiang ZS
Frontiers in physiology 2021;12:656139
Frontiers in physiology 2021;12:656139
SARS-CoV-2 Accessory Protein ORF7b Mediates Tumor Necrosis Factor-α-Induced Apoptosis in Cells.
Yang R, Zhao Q, Rao J, Zeng F, Yuan S, Ji M, Sun X, Li J, Yang J, Cui J, Jin Z, Liu L, Liu Z
Frontiers in microbiology 2021;12:654709
Frontiers in microbiology 2021;12:654709
Interferon-Lambda 1 Inhibits Staphylococcus aureus Colonization in Human Primary Keratinocytes.
Wu X, Zhao Y, Gu Y, Li K, Wang X, Zhang J
Frontiers in pharmacology 2021;12:652302
Frontiers in pharmacology 2021;12:652302
The Treatment of Rhodiola Mimics Exercise to Resist High-Fat Diet-Induced Muscle Dysfunction via Sirtuin1-Dependent Mechanisms.
You B, Dun Y, Fu S, Qi D, Zhang W, Liu Y, Qiu L, Xie M, Liu S
Frontiers in pharmacology 2021;12:646489
Frontiers in pharmacology 2021;12:646489
Anti-Hyperuricemic and Nephroprotective Effects of Dihydroberberine in Potassium Oxonate- and Hypoxanthine-Induced Hyperuricemic Mice.
Xu L, Lin G, Yu Q, Li Q, Mai L, Cheng J, Xie J, Liu Y, Su Z, Li Y
Frontiers in pharmacology 2021;12:645879
Frontiers in pharmacology 2021;12:645879
Bellidifolin Ameliorates Isoprenaline-Induced Myocardial Fibrosis by Regulating TGF-β1/Smads and p38 Signaling and Preventing NR4A1 Cytoplasmic Localization.
Yang HX, Sun JH, Yao TT, Li Y, Xu GR, Zhang C, Liu XC, Zhou WW, Song QH, Zhang Y, Li AY
Frontiers in pharmacology 2021;12:644886
Frontiers in pharmacology 2021;12:644886
Berberine Attenuates Chronic Atrophic Gastritis Induced by MNNG and Its Potential Mechanism.
Tong Y, Liu L, Wang R, Yang T, Wen J, Wei S, Jing M, Zou W, Zhao Y
Frontiers in pharmacology 2021;12:644638
Frontiers in pharmacology 2021;12:644638
Effects of Allicin on Late Sodium Current Caused by ΔKPQ-SCN5A Mutation in HEK293 Cells.
Chen Y, Huang Y, Bai J, Liu C, Ma S, Li J, Lu X, Fu Z, Fang L, Li Y, Zhang J
Frontiers in physiology 2021;12:636485
Frontiers in physiology 2021;12:636485
The Crucial Role of PPARγ-Egr-1-Pro-Inflammatory Mediators Axis in IgG Immune Complex-Induced Acute Lung Injury.
Yan C, Chen J, Ding Y, Zhou Z, Li B, Deng C, Yuan D, Zhang Q, Wang X
Frontiers in immunology 2021;12:634889
Frontiers in immunology 2021;12:634889
Repurposing of Pirfenidone (Anti-Pulmonary Fibrosis Drug) for Treatment of Rheumatoid Arthritis.
Gan D, Cheng W, Ke L, Sun AR, Jia Q, Chen J, Lin J, Li J, Xu Z, Zhang P
Frontiers in pharmacology 2021;12:631891
Frontiers in pharmacology 2021;12:631891
Jian-Pi-Yi-Shen Formula Ameliorates Oxidative Stress, Inflammation, and Apoptosis by Activating the Nrf2 Signaling in 5/6 Nephrectomized Rats.
Zhou F, Zou X, Zhang J, Wang Z, Yang Y, Wang D
Frontiers in pharmacology 2021;12:630210
Frontiers in pharmacology 2021;12:630210
Sinomenine Attenuated Capsaicin-Induced Increase in Cough Sensitivity in Guinea Pigs by Inhibiting SOX5/TRPV1 Axis and Inflammatory Response.
Ma JL, Ji K, Shi LQ, Li NN, Wang LY, Dong SJ, Zhang YX, Wen SH, Liu XM, Wang Y, Luo JY
Frontiers in physiology 2021;12:629276
Frontiers in physiology 2021;12:629276
Remdesivir Inhibits Tubulointerstitial Fibrosis in Obstructed Kidneys.
Xu L, Tan B, Huang D, Yuan M, Li T, Wu M, Ye C
Frontiers in pharmacology 2021;12:626510
Frontiers in pharmacology 2021;12:626510
Compound Dihuang Granule Inhibits Nigrostriatal Pathway Apoptosis in Parkinson's Disease by Suppressing the JNK/AP-1 Pathway.
Wang L, Yang YF, Chen L, He ZQ, Bi DY, Zhang L, Xu YW, He JC
Frontiers in pharmacology 2021;12:621359
Frontiers in pharmacology 2021;12:621359
MicroRNA-497 Reduction and Increase of Its Family Member MicroRNA-424 Lead to Dysregulation of Multiple Inflammation Related Genes in Synovial Fibroblasts With Rheumatoid Arthritis.
Wang S, Xu J, Guo Y, Cai Y, Ren X, Zhu W, Geng M, Meng L, Jiang C, Lu S
Frontiers in immunology 2021;12:619392
Frontiers in immunology 2021;12:619392
Hepatitis B Surface Antigen Suppresses the Activation of Nuclear Factor Kappa B Pathway via Interaction With the TAK1-TAB2 Complex.
Deng F, Xu G, Cheng Z, Huang Y, Ma C, Luo C, Yu C, Wang J, Xu X, Liu S, Zhu Y
Frontiers in immunology 2021;12:618196
Frontiers in immunology 2021;12:618196
Quercitrin Attenuates Acetaminophen-Induced Acute Liver Injury by Maintaining Mitochondrial Complex I Activity.
Xiong W, Yuan Z, Wang T, Wu S, Xiong Y, Yao Y, Yang Y, Wu H
Frontiers in pharmacology 2021;12:586010
Frontiers in pharmacology 2021;12:586010
PRMT5 functionally associates with EZH2 to promote colorectal cancer progression through epigenetically repressing CDKN2B expression.
Yang L, Ma DW, Cao YP, Li DZ, Zhou X, Feng JF, Bao J
Theranostics 2021;11(8):3742-3759
Theranostics 2021;11(8):3742-3759
Inhibition of BAG3 enhances the anticancer effect of shikonin in hepatocellular carcinoma.
Lu J, Liu SY, Zhang J, Yang GM, Gao GB, Yu NN, Li YP, Li YX, Ma ZQ, Wang Y, Lu CH
American journal of cancer research 2021;11(7):3575-3593
American journal of cancer research 2021;11(7):3575-3593
Honokiol induces ferroptosis in colon cancer cells by regulating GPX4 activity.
Guo C, Liu P, Deng G, Han Y, Chen Y, Cai C, Shen H, Deng G, Zeng S
American journal of cancer research 2021;11(6):3039-3054
American journal of cancer research 2021;11(6):3039-3054
NONO phase separation enhances DNA damage repair by accelerating nuclear EGFR-induced DNA-PK activation.
Fan XJ, Wang YL, Zhao WW, Bai SM, Ma Y, Yin XK, Feng LL, Feng WX, Wang YN, Liu Q, Hung MC, Wan XB
American journal of cancer research 2021;11(6):2838-2852
American journal of cancer research 2021;11(6):2838-2852
Platelet-derived microvesicles induce calcium oscillations and promote VSMC migration via TRPV4.
Li SS, Gao S, Chen Y, Bao H, Li ZT, Yao QP, Liu JT, Wang Y, Qi YX
Theranostics 2021;11(5):2410-2423
Theranostics 2021;11(5):2410-2423
Glycosylation of Siglec15 promotes immunoescape and tumor growth.
Wang YL, Wei MB, Zhao WW, Feng LL, Yin XK, Bai SM, Wan XB, Hung MC, Zou AZ, Wang MH, Zheng J, Qin C, Fan XJ
American journal of cancer research 2021;11(5):2291-2302
American journal of cancer research 2021;11(5):2291-2302
YY1-mediated reticulocalbin-2 upregulation promotes the hepatocellular carcinoma progression via activating MYC signaling.
Mei C, Jiang X, Gu Y, Wu X, Ma W, Chen X, Wang G, Yao Y, Liu Y, Zhang Z, Yuan Y
American journal of cancer research 2021;11(5):2238-2251
American journal of cancer research 2021;11(5):2238-2251
TSL-1502, a glucuronide prodrug of a poly (ADP-ribose) polymerase (PARP) inhibitor, exhibits potent anti-tumor activity in preclinical models.
Wang L, Zhu X, Li L, Li L, Fu L, Li Y, Fu H, Chen X, Lou L
American journal of cancer research 2021;11(4):1632-1645
American journal of cancer research 2021;11(4):1632-1645
TM2D1 contributes the epithelial-mesenchymal transition of hepatocellular carcinoma via modulating AKT/β-catenin axis.
Hu JW, Yin Y, Gao Y, Nie YY, Fu PY, Cai JB, Zhu K, Huang C, Huang XW, Yang XR, Cao Y, Qiu SJ, Fan J, Zhou J
American journal of cancer research 2021;11(4):1557-1571
American journal of cancer research 2021;11(4):1557-1571
A Mitochondrial DNA Variant Elevates the Risk of Gallstone Disease by Altering Mitochondrial Function.
Sun D, Niu Z, Zheng HX, Wu F, Jiang L, Han TQ, Wei Y, Wang J, Jin L
Cellular and molecular gastroenterology and hepatology 2021;11(4):1211-1226.e15
Cellular and molecular gastroenterology and hepatology 2021;11(4):1211-1226.e15
Loss of BRMS2 induces cell growth inhibition and translation capacity reduction in colorectal cancer cells.
Liu Y, Xu W, Xu X, Tan Z, Xu J, Ma L, Du P, Yang Y
American journal of cancer research 2021;11(3):930-944
American journal of cancer research 2021;11(3):930-944
S100A11 Promotes Liver Steatosis via FOXO1-Mediated Autophagy and Lipogenesis.
Zhang L, Zhang Z, Li C, Zhu T, Gao J, Zhou H, Zheng Y, Chang Q, Wang M, Wu J, Ran L, Wu Y, Miao H, Zou X, Liang B
Cellular and molecular gastroenterology and hepatology 2021;11(3):697-724
Cellular and molecular gastroenterology and hepatology 2021;11(3):697-724
Exosome-mediated delivery of inflammation-responsive Il-10 mRNA for controlled atherosclerosis treatment.
Bu T, Li Z, Hou Y, Sun W, Zhang R, Zhao L, Wei M, Yang G, Yuan L
Theranostics 2021;11(20):9988-10000
Theranostics 2021;11(20):9988-10000
Rapid design and development of CRISPR-Cas13a targeting SARS-CoV-2 spike protein.
Wang L, Zhou J, Wang Q, Wang Y, Kang C
Theranostics 2021;11(2):649-664
Theranostics 2021;11(2):649-664
Designer exosomes for targeted and efficient ferroptosis induction in cancer via chemo-photodynamic therapy.
Du J, Wan Z, Wang C, Lu F, Wei M, Wang D, Hao Q
Theranostics 2021;11(17):8185-8196
Theranostics 2021;11(17):8185-8196
TRPV2-spike protein interaction mediates the entry of SARS-CoV-2 into macrophages in febrile conditions.
Xu J, Yang Y, Hou Z, Jia H, Wang Y
Theranostics 2021;11(15):7379-7390
Theranostics 2021;11(15):7379-7390
Nanoparticle encapsulation of non-genotoxic p53 activator Inauhzin-C for improved therapeutic efficacy.
Bhattarai N, Wang J, Nguyen D, Yang X, Helmers L, Paruch J, Li L, Zhang Y, Meng K, Wang A, Jayawickramarajah J, Wang B, Zeng S, Lu H
Theranostics 2021;11(14):7005-7017
Theranostics 2021;11(14):7005-7017
A nano-predator of pathological MDMX construct by clearable supramolecular gold(I)-thiol-peptide complexes achieves safe and potent anti-tumor activity.
Yan S, Yan J, Liu D, Li X, Kang Q, You W, Zhang J, Wang L, Tian Z, Lu W, Liu W, He W
Theranostics 2021;11(14):6833-6846
Theranostics 2021;11(14):6833-6846
KAT6A, a novel regulator of β-catenin, promotes tumorigenicity and chemoresistance in ovarian cancer by acetylating COP1.
Liu W, Zhan Z, Zhang M, Sun B, Shi Q, Luo F, Zhang M, Zhang W, Hou Y, Xiao X, Li Y, Feng H
Theranostics 2021;11(13):6278-6292
Theranostics 2021;11(13):6278-6292
Relieving lipid accumulation through UCP1 suppresses the progression of acute kidney injury by promoting the AMPK/ULK1/autophagy pathway.
Xiong W, Xiong Z, Song A, Lei C, Ye C, Zhang C
Theranostics 2021;11(10):4637-4654
Theranostics 2021;11(10):4637-4654
Cardiac telocytes inhibit cardiac microvascular endothelial cell apoptosis through exosomal miRNA-21-5p-targeted cdip1 silencing to improve angiogenesis following myocardial infarction.
Liao Z, Chen Y, Duan C, Zhu K, Huang R, Zhao H, Hintze M, Pu Q, Yuan Z, Lv L, Chen H, Lai B, Feng S, Qi X, Cai D
Theranostics 2021;11(1):268-291
Theranostics 2021;11(1):268-291
KB-68A7.1 Inhibits Hepatocellular Carcinoma Development Through Binding to NSD1 and Suppressing Wnt/β-Catenin Signalling.
Zhang S, Xu J, Cao H, Jiang M, Xiong J
Frontiers in oncology 2021;11:808291
Frontiers in oncology 2021;11:808291
CDKN2A Deletion Leading to Hematogenous Metastasis of Human Gastric Carcinoma.
Qiao J, Tian Y, Cheng X, Liu Z, Zhou J, Gu L, Zhang B, Zhang L, Ji J, Xing R, Deng D
Frontiers in oncology 2021;11:801219
Frontiers in oncology 2021;11:801219
MAPK Activated Protein Kinase 3 Is a Prognostic-Related Biomarker and Associated With Immune Infiltrates in Glioma.
Ren J, Sun J, Li M, Zhang Z, Yang D, Cao H
Frontiers in oncology 2021;11:793025
Frontiers in oncology 2021;11:793025
SARS-CoV-2 Spike Antagonizes Innate Antiviral Immunity by Targeting Interferon Regulatory Factor 3.
Freitas RS, Crum TF, Parvatiyar K
Frontiers in cellular and infection microbiology 2021;11:789462
Frontiers in cellular and infection microbiology 2021;11:789462
The Circ_0001367/miR-545-3p/LUZP1 Axis Regulates Cell Proliferation, Migration and Invasion in Glioma Cells.
Dong X, Zhang P, Liu L, Li H, Cheng S, Li S, Wang Y, Zheng C, Dong J, Zhang L
Frontiers in oncology 2021;11:781471
Frontiers in oncology 2021;11:781471
Downregulation of SLC27A6 by DNA Hypermethylation Promotes Proliferation but Suppresses Metastasis of Nasopharyngeal Carcinoma Through Modulating Lipid Metabolism.
Zhong X, Yang Y, Li B, Liang P, Huang Y, Zheng Q, Wang Y, Xiao X, Mo Y, Zhang Z, Zhou X, Huang G, Zhao W
Frontiers in oncology 2021;11:780410
Frontiers in oncology 2021;11:780410
Preclinical Evaluation of the HDAC Inhibitor Chidamide in Transformed Follicular Lymphoma.
Zhong M, Tan J, Pan G, Jiang Y, Zhou H, Lai Q, Chen Q, Fan L, Deng M, Xu B, Zha J
Frontiers in oncology 2021;11:780118
Frontiers in oncology 2021;11:780118
Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Membrane (M) and Spike (S) Proteins Antagonize Host Type I Interferon Response.
Zhang Q, Chen Z, Huang C, Sun J, Xue M, Feng T, Pan W, Wang K, Dai J
Frontiers in cellular and infection microbiology 2021;11:766922
Frontiers in cellular and infection microbiology 2021;11:766922
GPI Is a Prognostic Biomarker and Correlates With Immune Infiltrates in Lung Adenocarcinoma.
Han J, Deng X, Sun R, Luo M, Liang M, Gu B, Zhang T, Peng Z, Lu Y, Tian C, Yan Y, Luo Z
Frontiers in oncology 2021;11:752642
Frontiers in oncology 2021;11:752642
A Class of Protein-Coding RNAs Binds to Polycomb Repressive Complex 2 and Alters Histone Methylation.
Liao M, Sun X, Gao S, Zhang Y
Frontiers in oncology 2021;11:739830
Frontiers in oncology 2021;11:739830
Combination of Auranofin and ICG-001 Suppress the Proliferation and Metastasis of Colon Cancer.
Lin Z, Li Q, Zhao Y, Lin Z, Cheng N, Zhang D, Liu G, Lin J, Zhang H, Lin D
Frontiers in oncology 2021;11:738085
Frontiers in oncology 2021;11:738085
Pseudomonas aeruginosa PcrV Enhances the Nitric Oxide-Mediated Tumoricidal Activity of Tumor-Associated Macrophages via a TLR4/PI3K/AKT/mTOR-Glycolysis-Nitric Oxide Circuit.
Yu H, Bai Y, Qiu J, He X, Xiong J, Dai Q, Wang X, Li Y, Sheng H, Xin R, Jiang L, Li Q, Li D, Zhang H, Zhang L, Chen Q, Peng J, Hu X, Zhang K
Frontiers in oncology 2021;11:736882
Frontiers in oncology 2021;11:736882
DEAD-Box Helicase DDX6 Facilitated RIG-I-Mediated Type-I Interferon Response to EV71 Infection.
Zhang R, Cheng M, Liu B, Yuan M, Chen D, Wang Y, Wu Z
Frontiers in cellular and infection microbiology 2021;11:725392
Frontiers in cellular and infection microbiology 2021;11:725392
TFCP2 Overcomes Senescence by Cooperating With SREBP2 to Activate Cholesterol Synthesis in Pancreatic Cancer.
Zhang D, Lu P, Zhu K, Wu H, Dai Y
Frontiers in oncology 2021;11:724437
Frontiers in oncology 2021;11:724437
LncRNA LGALS8-AS1 Promotes Breast Cancer Metastasis Through miR-125b-5p/SOX12 Feedback Regulatory Network.
Zhai D, Li T, Ye R, Bi J, Kuang X, Shi Y, Shao N, Lin Y
Frontiers in oncology 2021;11:711684
Frontiers in oncology 2021;11:711684
Siglec-15 Promotes Tumor Progression in Osteosarcoma via DUSP1/MAPK Pathway.
Fan MK, Zhang GC, Chen W, Qi LL, Xie MF, Zhang YY, Wang L, Zhang Q
Frontiers in oncology 2021;11:710689
Frontiers in oncology 2021;11:710689
METTL3 Promotes the Resistance of Glioma to Temozolomide via Increasing MGMT and ANPG in a m(6)A Dependent Manner.
Shi J, Chen G, Dong X, Li H, Li S, Cheng S, Li Y, Wang L, Yuan J, Qian Z, Dong J
Frontiers in oncology 2021;11:702983
Frontiers in oncology 2021;11:702983
SPNS2 Downregulation Induces EMT and Promotes Colorectal Cancer Metastasis via Activating AKT Signaling Pathway.
Lv L, Yi Q, Yan Y, Chao F, Li M
Frontiers in oncology 2021;11:682773
Frontiers in oncology 2021;11:682773
TIPE2 Suppresses Malignancy of Pancreatic Cancer Through Inhibiting TGFβ1 Mediated Signaling Pathway.
Feng F, Liu C, Bian H, Cai W, Zhou Y, Zhou L, Zhuang Z
Frontiers in oncology 2021;11:680985
Frontiers in oncology 2021;11:680985
Downregulation of miR-135b-5p Suppresses Progression of Esophageal Cancer and Contributes to the Effect of Cisplatin.
Di Y, Jiang Y, Shen X, Liu J, Gao Y, Cai H, Sun X, Ning D, Liu B, Lei J, Jin S
Frontiers in oncology 2021;11:679348
Frontiers in oncology 2021;11:679348
miR-1258 Attenuates Tumorigenesis Through Targeting E2F1 to Inhibit PCNA and MMP2 Transcription in Glioblastoma.
Qin H, Gui Y, Ma R, Zhang H, Guo Y, Ye Y, Li J, Zhao L, Wang Y
Frontiers in oncology 2021;11:671144
Frontiers in oncology 2021;11:671144
The Deubiquitinase USP39 Promotes ESCC Tumorigenesis Through Pre-mRNA Splicing of the mTORC2 Component Rictor.
Zhao Y, Geng H, Liu G, Ji Q, Cheng X, Li X, Liu W, Thorne RF, Zhang R, Liu X
Frontiers in oncology 2021;11:667495
Frontiers in oncology 2021;11:667495
Pinocembrin Inhibits the Proliferation and Metastasis of Breast Cancer via Suppression of the PI3K/AKT Signaling Pathway.
Zhu X, Li R, Wang C, Zhou S, Fan Y, Ma S, Gao D, Gai N, Yang J
Frontiers in oncology 2021;11:661184
Frontiers in oncology 2021;11:661184
N2E4, a Monoclonal Antibody Targeting Neuropilin-2, Inhibits Tumor Growth and Metastasis in Pancreatic Ductal Adenocarcinoma via Suppressing FAK/Erk/HIF-1α Signaling.
Wang L, Wang L, Wang S, Zhou Z, Liu Z, Xu P, Luo X, Wu T, Luo F, Yan J
Frontiers in oncology 2021;11:657008
Frontiers in oncology 2021;11:657008
A Novel Mechanism of the c-Myc/NEAT1 Axis Mediating Colorectal Cancer Cell Response to Photodynamic Therapy Treatment.
Liu K, Lei S, Kuang Y, Jin Q, Long D, Liu C, Jiang Y, Zhao H, Yao H
Frontiers in oncology 2021;11:652831
Frontiers in oncology 2021;11:652831
Analysis of Long Noncoding RNAs in Aila-Induced Non-Small Cell Lung Cancer Inhibition.
Chen L, Wu C, Wang H, Chen S, Ma D, Tao Y, Wang X, Luan Y, Wang T, Shi Y, Song G, Zhao Y, Dong X, Wang B
Frontiers in oncology 2021;11:652567
Frontiers in oncology 2021;11:652567
MiR-489-3p Reduced Pancreatic Cancer Proliferation and Metastasis By Targeting PKM2 and LDHA Involving Glycolysis.
Zhang D, He Z, Shen Y, Wang J, Liu T, Jiang J
Frontiers in oncology 2021;11:651535
Frontiers in oncology 2021;11:651535
SLC1A4: A Powerful Prognostic Marker and Promising Therapeutic Target for HCC.
Peng X, Chen R, Cai S, Lu S, Zhang Y
Frontiers in oncology 2021;11:650355
Frontiers in oncology 2021;11:650355
LncRNA SNHG8 Promotes Proliferation and Inhibits Apoptosis of Diffuse Large B-Cell Lymphoma via Sponging miR-335-5p.
Yu B, Wang B, Wu Z, Wu C, Ling J, Gao X, Zeng H
Frontiers in oncology 2021;11:650287
Frontiers in oncology 2021;11:650287
Long Noncoding RNA SNHG12 Promotes Gastric Cancer Proliferation by Binding to HuR and Stabilizing YWHAZ Expression Through the AKT/GSK-3β Pathway.
Zhang T, Beeharry MK, Zheng Y, Wang Z, Li J, Zhu Z, Li C
Frontiers in oncology 2021;11:645832
Frontiers in oncology 2021;11:645832
The Overexpression of Acyl-CoA Medium-Chain Synthetase-3 (ACSM3) Suppresses the Ovarian Cancer Progression via the Inhibition of Integrin β1/AKT Signaling Pathway.
Yan L, He Z, Li W, Liu N, Gao S
Frontiers in oncology 2021;11:644840
Frontiers in oncology 2021;11:644840
TFEB Promotes Prostate Cancer Progression via Regulating ABCA2-Dependent Lysosomal Biogenesis.
Zhu X, Zhuo Y, Wu S, Chen Y, Ye J, Deng Y, Feng Y, Liu R, Cai S, Zou Z, Wang B, Wu CL, Zeng G, Zhong W
Frontiers in oncology 2021;11:632524
Frontiers in oncology 2021;11:632524
DDX19A Promotes Metastasis of Cervical Squamous Cell Carcinoma by Inducing NOX1-Mediated ROS Production.
Jiang Y, Wang B, Li Y, Shen J, Wei Y, Li H, Chen S, Yang H, Zeng F, Liu C, Wang F, He H, Chen Y, Liu J
Frontiers in oncology 2021;11:629974
Frontiers in oncology 2021;11:629974
circATP2B1 Promotes Aerobic Glycolysis in Gastric Cancer Cells Through Regulation of the miR-326 Gene Cluster.
Zhao X, Tian Z, Liu L
Frontiers in oncology 2021;11:628624
Frontiers in oncology 2021;11:628624
Overexpressed Tumor Suppressor Exosomal miR-15a-5p in Cancer Cells Inhibits PD1 Expression in CD8+T Cells and Suppresses the Hepatocellular Carcinoma Progression.
Zhang HY, Liang HX, Wu SH, Jiang HQ, Wang Q, Yu ZJ
Frontiers in oncology 2021;11:622263
Frontiers in oncology 2021;11:622263
Identification and Confirmation of the miR-30 Family as a Potential Central Player in Tobacco-Related Head and Neck Squamous Cell Carcinoma.
Zhang T, Zhu X, Sun Q, Qin X, Zhang Z, Feng Y, Yan M, Chen W
Frontiers in oncology 2021;11:616372
Frontiers in oncology 2021;11:616372
miR-4461 Regulates the Proliferation and Metastasis of Ovarian Cancer Cells and Cisplatin Resistance.
Dou L, Zhang Y
Frontiers in oncology 2021;11:614035
Frontiers in oncology 2021;11:614035
miR-139-5p Loss-Mediated WTAP Activation Contributes to Hepatocellular Carcinoma Progression by Promoting the Epithelial to Mesenchymal Transition.
Liu W, Gao X, Chen X, Zhao N, Sun Y, Zou Y, Guan Y, Yang L, Pei X, Wang G, Wang B, Li M, Song W
Frontiers in oncology 2021;11:611544
Frontiers in oncology 2021;11:611544
PSMC2 Regulates Cell Cycle Progression Through the p21/Cyclin D1 Pathway and Predicts a Poor Prognosis in Human Hepatocellular Carcinoma.
Liu Y, Chen H, Li X, Zhang F, Kong L, Wang X, Bai J, Wu X
Frontiers in oncology 2021;11:607021
Frontiers in oncology 2021;11:607021
The Role of Tim-3 on dNK Cells Dysfunction During Abnormal Pregnancy With Toxoplasma gondii Infection.
Li T, Cui L, Xu X, Zhang H, Jiang Y, Ren L, Yang C, Liu X, Hu X
Frontiers in cellular and infection microbiology 2021;11:587150
Frontiers in cellular and infection microbiology 2021;11:587150
Bispecific c-Met/PD-L1 CAR-T Cells Have Enhanced Therapeutic Effects on Hepatocellular Carcinoma.
Jiang W, Li T, Guo J, Wang J, Jia L, Shi X, Yang T, Jiao R, Wei X, Feng Z, Tang Q, Ji G
Frontiers in oncology 2021;11:546586
Frontiers in oncology 2021;11:546586
Schisandrin Restores the Amyloid β-Induced Impairments on Mitochondrial Function, Energy Metabolism, Biogenesis, and Dynamics in Rat Primary Hippocampal Neurons.
Piao Z, Song L, Yao L, Zhang L, Lu Y
Pharmacology 2021;106(5-6):254-264
Pharmacology 2021;106(5-6):254-264
Preliminary therapeutic and mechanistic evaluation of S-allylmercapto-N-acetylcysteine in the treatment of pulmonary emphysema.
Zheng D, Wang J, Li G, Sun Y, Deng Q, Li M, Song K, Zhao Z
International immunopharmacology 2021 Sep;98:107913
International immunopharmacology 2021 Sep;98:107913
Protective effect and mechanism of nicotinamide adenine dinucleotide against optic neuritis in mice with experimental autoimmune encephalomyelitis.
Guo J, Li B, Wang J, Guo R, Tian Y, Song S, Guo L
International immunopharmacology 2021 Sep;98:107846
International immunopharmacology 2021 Sep;98:107846
ITPRIP promotes glioma progression by linking MYL9 to DAPK1 inhibition.
Cao C, He K, Li S, Ge Q, Liu L, Zhang Z, Zhang H, Wang X, Sun X, Ding L
Cellular signalling 2021 Sep;85:110062
Cellular signalling 2021 Sep;85:110062
CPEB1 enhances erastin-induced ferroptosis in gastric cancer cells by suppressing twist1 expression.
Wang J, Wang T, Zhang Y, Liu J, Song J, Han Y, Wang L, Yang S, Zhu L, Geng R, Li W, Yu X
IUBMB life 2021 Sep;73(9):1180-1190
IUBMB life 2021 Sep;73(9):1180-1190
ZMPSTE24 Regulates SARS-CoV-2 Spike Protein-enhanced Expression of Endothelial PAI-1.
Han M, Pandey D
American journal of respiratory cell and molecular biology 2021 Sep;65(3):300-308
American journal of respiratory cell and molecular biology 2021 Sep;65(3):300-308
MiR-499a prevents astrocytes mediated inflammation in ischemic stroke by targeting PTEN.
Guan X, Zhang Y, Gareev I, Beylerli O, Li X, Lu G, Lv L, Hai X
Non-coding RNA research 2021 Sep;6(3):146-152
Non-coding RNA research 2021 Sep;6(3):146-152
Riluzole does not ameliorate disease caused by cytoplasmic TDP-43 in a mouse model of amyotrophic lateral sclerosis.
Wright AL, Della Gatta PA, Le S, Berning BA, Mehta P, Jacobs KR, Gul H, San Gil R, Hedl TJ, Riddell WR, Watson O, Keating SS, Venturato J, Chung RS, Atkin JD, Lee A, Shi B, Blizzard CA, Morsch M, Walker AK
The European journal of neuroscience 2021 Sep;54(6):6237-6255
The European journal of neuroscience 2021 Sep;54(6):6237-6255
TAZ as a novel regulator of oxidative damage in decidualization via Nrf2/ARE/Foxo1 pathway.
Yu HF, Zheng LW, Yang ZQ, Wang YS, Wang TT, Yue ZP, Guo B
Experimental & molecular medicine 2021 Sep;53(9):1307-1318
Experimental & molecular medicine 2021 Sep;53(9):1307-1318
M2-polarized macrophages mediate wound healing by regulating connective tissue growth factor via AKT, ERK1/2, and STAT3 signaling pathways.
Zhang SM, Wei CY, Wang Q, Wang L, Lu L, Qi FZ
Molecular biology reports 2021 Sep;48(9):6443-6456
Molecular biology reports 2021 Sep;48(9):6443-6456
Activation of Transient Receptor Potential Ankyrin 1 and Vanilloid 1 Channels Promotes Odontogenic Differentiation of Human Dental Pulp Cells.
Lou Y, Liu Y, Zhao J, Tian W, Xu N, Zang C, Que K
Journal of endodontics 2021 Sep;47(9):1409-1416
Journal of endodontics 2021 Sep;47(9):1409-1416
Identifying miRNA modules associated with progression of keloids through weighted gene co-expression network analysis and experimental validation in vitro.
Lv W, Ren Y, Wu M, Luo X, Yu J, Zhang Q, Wu Y
Burns : journal of the International Society for Burn Injuries 2021 Sep;47(6):1359-1372
Burns : journal of the International Society for Burn Injuries 2021 Sep;47(6):1359-1372
miR-138 inhibits epithelial-mesenchymal transition in silica-induced pulmonary fibrosis by regulating ZEB2.
Wu Q, Gui W, Jiao B, Han L, Wang F
Toxicology 2021 Sep;461:152925
Toxicology 2021 Sep;461:152925
miRNA‑7515 suppresses pancreatic cancer cell proliferation, migration and invasion via downregulating IGF‑1 expression.
Lei S, Zeng Z, He Z, Cao W
Oncology reports 2021 Sep;46(3)
Oncology reports 2021 Sep;46(3)
Chronic stress promotes glioma cell proliferation via the PI3K/Akt signaling pathway.
Zhang ZQ, Wang X, Xue BH, Zhao Y, Xie F, Wang SD, Xue C, Wang Y, Zhang YS, Qian LJ
Oncology reports 2021 Sep;46(3)
Oncology reports 2021 Sep;46(3)
MicroRNA-214 contributes to Ang II-induced cardiac hypertrophy by targeting SIRT3 to provoke mitochondrial malfunction.
Ding YQ, Zhang YH, Lu J, Li B, Yu WJ, Yue ZB, Hu YH, Wang PX, Li JY, Cai SD, Ye JT, Liu PQ
Acta pharmacologica Sinica 2021 Sep;42(9):1422-1436
Acta pharmacologica Sinica 2021 Sep;42(9):1422-1436
Genetically encoded FRET fluorescent sensor designed for detecting MOF histone acetyltransferase activity in vitro and in living cells.
Han Q, Chen F, Liu S, Ge Y, Wu J, Liu D
Analytical and bioanalytical chemistry 2021 Sep;413(21):5453-5461
Analytical and bioanalytical chemistry 2021 Sep;413(21):5453-5461
In Vivo Characterization of Endogenous Cardiovascular Extracellular Vesicles in Larval and Adult Zebrafish.
Scott A, Sueiro Ballesteros L, Bradshaw M, Tsuji C, Power A, Lorriman J, Love J, Paul D, Herman A, Emanueli C, Richardson RJ
Arteriosclerosis, thrombosis, and vascular biology 2021 Sep;41(9):2454-2468
Arteriosclerosis, thrombosis, and vascular biology 2021 Sep;41(9):2454-2468
The scaffold protein IQGAP1 links heat-induced stress signals to alternative splicing regulation in gastric cancer cells.
Birladeanu AM, Rogalska M, Potiri M, Papadaki V, Andreadou M, Kontoyiannis DL, Lewis JD, Erpapazoglou Z, Kafasla P
Oncogene 2021 Sep;40(36):5518-5532
Oncogene 2021 Sep;40(36):5518-5532
miR-351-3p promotes rat amniotic fluid-derived mesenchymal stromal cell proliferation via targeting the coding sequence of Abca4.
Huang J, Zhao Q, Wei X, Ma W, Luo W, Gu H, Liu D, He Y, Huang T, Liu Y, Wang C, Yuan Z
Stem cells (Dayton, Ohio) 2021 Sep;39(9):1192-1206
Stem cells (Dayton, Ohio) 2021 Sep;39(9):1192-1206
FSH modulated cartilage ECM metabolism by targeting the PKA/CREB/SOX9 pathway.
Zhang M, Wang Y, Huan Z, Liu Y, Zhang W, Kong D, Kong L, Xu J
Journal of bone and mineral metabolism 2021 Sep;39(5):769-779
Journal of bone and mineral metabolism 2021 Sep;39(5):769-779
miRNA-10a-5p inhibits cell metastasis in hepatocellular carcinoma via targeting SKA1.
Shen D, Zhao HY, Gu AD, Wu YW, Weng YH, Li SJ, Song JY, Gu XF, Qiu J, Zhao W
The Kaohsiung journal of medical sciences 2021 Sep;37(9):784-794
The Kaohsiung journal of medical sciences 2021 Sep;37(9):784-794
Triclosan regulates the Nrf2/HO-1 pathway through the PI3K/Akt/JNK signaling cascade to induce oxidative damage in neurons.
Wang D, Liu J, Jiang H
Environmental toxicology 2021 Sep;36(9):1953-1964
Environmental toxicology 2021 Sep;36(9):1953-1964
TRIP13 exerts a cancer-promoting role in cervical cancer by enhancing Wnt/β-catenin signaling via ACTN4.
Liu X, Shen X, Zhang J
Environmental toxicology 2021 Sep;36(9):1829-1840
Environmental toxicology 2021 Sep;36(9):1829-1840
Hsp70 chaperones TDP-43 in dynamic, liquid-like phase and prevents it from amyloid aggregation.
Gu J, Wang C, Hu R, Li Y, Zhang S, Sun Y, Wang Q, Li D, Fang Y, Liu C
Cell research 2021 Sep;31(9):1024-1027
Cell research 2021 Sep;31(9):1024-1027
The deubiquitinase USP10 restores PTEN activity and inhibits non-small cell lung cancer cell proliferation.
He Y, Jiang S, Mao C, Zheng H, Cao B, Zhang Z, Zhao J, Zeng Y, Mao X
The Journal of biological chemistry 2021 Sep;297(3):101088
The Journal of biological chemistry 2021 Sep;297(3):101088
AMPK phosphorylates PPARδ to mediate its stabilization, inhibit glucose and glutamine uptake and colon tumor growth.
Ding J, Gou Q, Jia X, Liu Q, Jin J, Shi J, Hou Y
The Journal of biological chemistry 2021 Sep;297(3):100954
The Journal of biological chemistry 2021 Sep;297(3):100954
The inhibitory effect of the deubiquitinase cylindromatosis (CYLD) on inflammatory responses in human gingival fibroblasts.
Fu YW, Li L, Wang XQ, Zhou Y, Zhu LF, Mei YM, Xu Y
Oral diseases 2021 Sep;27(6):1487-1497
Oral diseases 2021 Sep;27(6):1487-1497
Human forebrain endothelial cell therapy for psychiatric disorders.
Datta D, Subburaju S, Kaye S, Baruah J, Choi YK, Nian Y, Khalili JS, Chung S, Elkhal A, Vasudevan A
Molecular psychiatry 2021 Sep;26(9):4864-4883
Molecular psychiatry 2021 Sep;26(9):4864-4883
N-3 polyunsaturated fatty acids promote astrocyte differentiation and neurotrophin production independent of cAMP in patient-derived neural stem cells.
Yu JZ, Wang J, Sheridan SD, Perlis RH, Rasenick MM
Molecular psychiatry 2021 Sep;26(9):4605-4615
Molecular psychiatry 2021 Sep;26(9):4605-4615
DNM3OS regulates GAPDH expression and influences the molecular pathogenesis of Huntington's disease.
Dong X, Cong S
Journal of cellular and molecular medicine 2021 Sep;25(18):9066-9071
Journal of cellular and molecular medicine 2021 Sep;25(18):9066-9071
The effects of NCBP3 on METTL3-mediated m6A RNA methylation to enhance translation process in hypoxic cardiomyocytes.
Ye F, Wang X, Tu S, Zeng L, Deng X, Luo W, Zhang Z
Journal of cellular and molecular medicine 2021 Sep;25(18):8920-8928
Journal of cellular and molecular medicine 2021 Sep;25(18):8920-8928
Effects of different intensities of continuous training on vascular inflammation and oxidative stress in spontaneously hypertensive rats.
Luo M, Cao C, Niebauer J, Yan J, Ma X, Chang Q, Zhang T, Huang X, Liu G
Journal of cellular and molecular medicine 2021 Sep;25(17):8522-8536
Journal of cellular and molecular medicine 2021 Sep;25(17):8522-8536
Abdominal paracentesis drainage attenuates intestinal mucosal barrier damage through macrophage polarization in severe acute pancreatitis.
Yuan X, Luo C, Wu J, Li W, Guo X, Li S, Wang B, Sun H, Tang L
Experimental biology and medicine (Maywood, N.J.) 2021 Sep;246(18):2029-2038
Experimental biology and medicine (Maywood, N.J.) 2021 Sep;246(18):2029-2038
miR‑140‑5p alleviates mouse liver ischemia/reperfusion injury by targeting CAPN1.
Yu Q, Chen S, Tang H, Yang H, Zhang J, Shi X, Li J, Guo W, Zhang S
Molecular medicine reports 2021 Sep;24(3)
Molecular medicine reports 2021 Sep;24(3)
Endoglin deficiency impairs VEGFR2 but not FGFR1 or TIE2 activation and alters VEGF-mediated cellular responses in human primary endothelial cells.
Zhang Q, Wang C, Cannavicci A, Faughnan ME, Kutryk MJB
Translational research : the journal of laboratory and clinical medicine 2021 Sep;235:129-143
Translational research : the journal of laboratory and clinical medicine 2021 Sep;235:129-143
PDIA6 promotes pancreatic cancer progression and immune escape through CSN5-mediated deubiquitination of β-catenin and PD-L1.
Ma Y, Xia P, Wang Z, Xu J, Zhang L, Jiang Y
Neoplasia (New York, N.Y.) 2021 Sep;23(9):912-928
Neoplasia (New York, N.Y.) 2021 Sep;23(9):912-928
PARP inhibitor niraparib as a radiosensitizer promotes antitumor immunity of radiotherapy in EGFR-mutated non-small cell lung cancer.
Zhang N, Gao Y, Zeng Z, Luo Y, Jiang X, Zhang J, Li J, Zhang J, Gong Y, Xie C
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 2021 Sep;23(9):1827-1837
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 2021 Sep;23(9):1827-1837
Human Bone Mesenchymal Stem Cell-Derived Exosomes Inhibit IL-1β-Induced Inflammation in Osteoarthritis Chondrocytes.
Zhou L, Ye H, Liu L, Chen Y
Cell journal 2021 Sep;23(4):485-494
Cell journal 2021 Sep;23(4):485-494
OGT regulated O-GlcNacylation promotes migration and invasion by activating IL-6/STAT3 signaling in NSCLC cells.
Ge X, Peng X, Li M, Ji F, Chen J, Zhang D
Pathology, research and practice 2021 Sep;225:153580
Pathology, research and practice 2021 Sep;225:153580
PPP1CA/YAP/GS/Gln/mTORC1 pathway activates retinal Müller cells during diabetic retinopathy.
Guo Y, Cang X, Zhu L, Zhu M, Li A, Wang Z, Zhang Y, Wang X, Song E
Experimental eye research 2021 Sep;210:108703
Experimental eye research 2021 Sep;210:108703
Interleukin-4 protects mice against lethal influenza and Streptococcus pneumoniae co-infected pneumonia.
Peng Y, Wang X, Wang H, Xu W, Wu K, Go X, Yin Y, Zhang X
Clinical and experimental immunology 2021 Sep;205(3):379-390
Clinical and experimental immunology 2021 Sep;205(3):379-390
MeCP2 prevents age-associated cognitive decline via restoring synaptic plasticity in a senescence-accelerated mouse model.
Huang JL, Zhang F, Su M, Li J, Yi W, Hou LX, Yang SM, Liu JY, Zhang HA, Ma T, Wu DP
Aging cell 2021 Sep;20(9):e13451
Aging cell 2021 Sep;20(9):e13451
P76RBE silencing inhibits ovarian cancer cell proliferation, migration, and invasion via suppressing the integrin β1/NF-κB pathway.
Yan L, He Z, Li W, Liu N, Gao S
Cell cycle (Georgetown, Tex.) 2021 Sep;20(18):1875-1889
Cell cycle (Georgetown, Tex.) 2021 Sep;20(18):1875-1889
Photoresponsive PAMAM-Assembled Nanocarrier Loaded with Autophagy Inhibitor for Synergistic Cancer Therapy.
Jing M, Li Y, Wang M, Zhang H, Wei P, Zhou Y, Ishimwe N, Huang X, Wang L, Wen L, Wang W, Zhang Y
Small (Weinheim an der Bergstrasse, Germany) 2021 Sep;17(38):e2102295
Small (Weinheim an der Bergstrasse, Germany) 2021 Sep;17(38):e2102295
The miR-28-5p-CAMTA2 axis regulates colon cancer progression via Wnt/β-catenin signaling.
Luan XF, Wang L, Gai XF
Journal of cellular biochemistry 2021 Sep;122(9):945-957
Journal of cellular biochemistry 2021 Sep;122(9):945-957
CENPA is one of the potential key genes associated with the proliferation and prognosis of ovarian cancer based on integrated bioinformatics analysis and regulated by MYBL2.
Han J, Xie R, Yang Y, Chen D, Liu L, Wu J, Li S
Translational cancer research 2021 Sep;10(9):4076-4086
Translational cancer research 2021 Sep;10(9):4076-4086
Orf Virus ORF120 Protein Positively Regulates the NF-κB Pathway by Interacting with G3BP1.
Zhou Y, Guan J, Gao F, Li Z, Lan Y, Lu H, Song D, Lv L, Lv P, Xu M, Wang Z, He H, Zhao K, He W
Journal of virology 2021 Sep 9;95(19):e0015321
Journal of virology 2021 Sep 9;95(19):e0015321
NSUN2 modified by SUMO-2/3 promotes gastric cancer progression and regulates mRNA m5C methylation.
Hu Y, Chen C, Tong X, Chen S, Hu X, Pan B, Sun X, Chen Z, Shi X, Hu Y, Shen X, Xue X, Lu M
Cell death & disease 2021 Sep 9;12(9):842
Cell death & disease 2021 Sep 9;12(9):842
HSP90 acts as a senomorphic target in senescent retinal pigmental epithelial cells.
Chen DD, Peng X, Wang Y, Jiang M, Xue M, Shang G, Liu X, Jia X, Liu B, Lu Y, Mu H, Zhang F, Hu Y
Aging 2021 Sep 8;13(17):21547-21570
Aging 2021 Sep 8;13(17):21547-21570
Microglia modulation with 1070-nm light attenuates Aβ burden and cognitive impairment in Alzheimer's disease mouse model.
Tao L, Liu Q, Zhang F, Fu Y, Zhu X, Weng X, Han H, Huang Y, Suo Y, Chen L, Gao X, Wei X
Light, science & applications 2021 Sep 8;10(1):179
Light, science & applications 2021 Sep 8;10(1):179
Cilium induction triggers differentiation of glioma stem cells.
Goranci-Buzhala G, Mariappan A, Ricci-Vitiani L, Josipovic N, Pacioni S, Gottardo M, Ptok J, Schaal H, Callaini G, Rajalingam K, Dynlacht B, Hadian K, Papantonis A, Pallini R, Gopalakrishnan J
Cell reports 2021 Sep 7;36(10):109656
Cell reports 2021 Sep 7;36(10):109656
m(6)A demethylase ALKBH5 suppression contributes to esophageal squamous cell carcinoma progression.
Xiao D, Fang TX, Lei Y, Xiao SJ, Xia JW, Lin TY, Li YL, Zhai JX, Li XY, Huang SH, Jia JS, Tian YG, Lin XL, Cai KC, Sun Y
Aging 2021 Sep 7;13(17):21497-21512
Aging 2021 Sep 7;13(17):21497-21512
The genomic architecture of EBV and infected gastric tissue from precursor lesions to carcinoma.
Chen ZH, Yan SM, Chen XX, Zhang Q, Liu SX, Liu Y, Luo YL, Zhang C, Xu M, Zhao YF, Huang LY, Liu BL, Xia TL, Xu DZ, Liang Y, Chen YM, Wang W, Yuan SQ, Zhang HZ, Yun JP, Zhai WW, Zeng MS, Bai F, Zhong Q
Genome medicine 2021 Sep 7;13(1):146
Genome medicine 2021 Sep 7;13(1):146
A ciliopathy complex builds distal appendages to initiate ciliogenesis.
Kumar D, Rains A, Herranz-Pérez V, Lu Q, Shi X, Swaney DL, Stevenson E, Krogan NJ, Huang B, Westlake C, Garcia-Verdugo JM, Yoder BK, Reiter JF
The Journal of cell biology 2021 Sep 6;220(9)
The Journal of cell biology 2021 Sep 6;220(9)
TDP-43 mediates SREBF2-regulated gene expression required for oligodendrocyte myelination.
Ho WY, Chang JC, Lim K, Cazenave-Gassiot A, Nguyen AT, Foo JC, Muralidharan S, Viera-Ortiz A, Ong SJM, Hor JH, Agrawal I, Hoon S, Arogundade OA, Rodriguez MJ, Lim SM, Kim SH, Ravits J, Ng SY, Wenk MR, Lee EB, Tucker-Kellogg G, Ling SC
The Journal of cell biology 2021 Sep 6;220(9)
The Journal of cell biology 2021 Sep 6;220(9)
Live Combined B. subtilis and E. faecium Alleviate Liver Inflammation, Improve Intestinal Barrier Function, and Modulate Gut Microbiota in Mice with Non-Alcoholic Fatty Liver Disease.
Jiang J, Xiong J, Ni J, Chen C, Wang K
Medical science monitor : international medical journal of experimental and clinical research 2021 Sep 5;27:e931143
Medical science monitor : international medical journal of experimental and clinical research 2021 Sep 5;27:e931143
Curcumol inhibits encephalomyocarditis virus by promoting IFN-β secretion.
Zheng J, Xu Y, Khan A, Sun P, Sun Y, Fan K, Yin W, Wang S, Li H, Sun N
BMC veterinary research 2021 Sep 30;17(1):318
BMC veterinary research 2021 Sep 30;17(1):318
Stimulation of ROS Generation by Extract of Warburgia ugandensis Leading to G(0)/G(1) Cell Cycle Arrest and Antiproliferation in A549 Cells.
Zhang YL, Chen GL, Liu Y, Zhuang XC, Guo MQ
Antioxidants (Basel, Switzerland) 2021 Sep 30;10(10)
Antioxidants (Basel, Switzerland) 2021 Sep 30;10(10)
HIF-1α/JMJD1A signaling regulates inflammation and oxidative stress following hyperglycemia and hypoxia-induced vascular cell injury.
Zhao M, Wang S, Zuo A, Zhang J, Wen W, Jiang W, Chen H, Liang D, Sun J, Wang M
Cellular & molecular biology letters 2021 Sep 3;26(1):40
Cellular & molecular biology letters 2021 Sep 3;26(1):40
Proximity Labeling, Quantitative Proteomics, and Biochemical Studies Revealed the Molecular Mechanism for the Inhibitory Effect of Indisulam on the Proliferation of Gastric Cancer Cells.
Lu J, Jiang H, Li D, Chen T, Wang Y, Pu Z, Xu G
Journal of proteome research 2021 Sep 3;20(9):4462-4474
Journal of proteome research 2021 Sep 3;20(9):4462-4474
Inhibition of DNMT-1 alleviates ferroptosis through NCOA4 mediated ferritinophagy during diabetes myocardial ischemia/reperfusion injury.
Li W, Li W, Wang Y, Leng Y, Xia Z
Cell death discovery 2021 Sep 29;7(1):267
Cell death discovery 2021 Sep 29;7(1):267
A Versatile Nanoplatform for Broad-Spectrum Immunotherapy by Reversing the Tumor Microenvironment.
Chen A, Yang F, Kuang J, Xiong Y, Mi BB, Zhou Y, Hu JJ, Song SJ, Wan T, Wan ZZ, Huang HY, Li XR, Song W, Qiu WX
ACS applied materials & interfaces 2021 Sep 29;13(38):45335-45345
ACS applied materials & interfaces 2021 Sep 29;13(38):45335-45345
Therapeutic Interaction of Apatinib and Chidamide in T-Cell Acute Lymphoblastic Leukemia through Interference with Mitochondria Associated Biogenesis and Intrinsic Apoptosis.
Zhong M, Lin F, Jiang Y, Pan G, Tan J, Zhou H, Lai Q, Chen Q, Deng M, Zha J, Xu B
Journal of personalized medicine 2021 Sep 29;11(10)
Journal of personalized medicine 2021 Sep 29;11(10)
A Novel Calpain Inhibitor Compound Has Protective Effects on a Zebrafish Model of Spinocerebellar Ataxia Type 3.
Robinson KJ, Yuan K, Plenderleith SK, Watchon M, Laird AS
Cells 2021 Sep 29;10(10)
Cells 2021 Sep 29;10(10)
Exosomal microRNA-588 from M2 polarized macrophages contributes to cisplatin resistance of gastric cancer cells.
Cui HY, Rong JS, Chen J, Guo J, Zhu JQ, Ruan M, Zuo RR, Zhang SS, Qi JM, Zhang BH
World journal of gastroenterology 2021 Sep 28;27(36):6079-6092
World journal of gastroenterology 2021 Sep 28;27(36):6079-6092
Engineering Extracellular Vesicles Restore the Impaired Cellular Uptake and Attenuate Intervertebral Disc Degeneration.
Liao Z, Liu H, Ma L, Lei J, Tong B, Li G, Ke W, Wang K, Feng X, Hua W, Li S, Yang C
ACS nano 2021 Sep 28;15(9):14709-14724
ACS nano 2021 Sep 28;15(9):14709-14724
Dual Inhibition of Endoplasmic Reticulum Stress and Oxidation Stress Manipulates the Polarization of Macrophages under Hypoxia to Sensitize Immunotherapy.
Jiang M, Li X, Zhang J, Lu Y, Shi Y, Zhu C, Liu Y, Qin B, Luo Z, Du Y, Luo L, Peng L, You J
ACS nano 2021 Sep 28;15(9):14522-14534
ACS nano 2021 Sep 28;15(9):14522-14534
Changes in energy metabolism and respiration in different tracheal narrowing in rats.
Segev Y, Nujedat H, Arazi E, Assadi MH, Tarasiuk A
Scientific reports 2021 Sep 27;11(1):19166
Scientific reports 2021 Sep 27;11(1):19166
Macrophage-mediated multi-mode drug release system for photothermal combined with anti-inflammatory therapy against postoperative recurrence of triple negative breast cancer.
Ren K, Qiu Y, Yu Q, He J, Mei L, Liu Y, Li J, Wang X, Li M, Zhang Z, He Q
International journal of pharmaceutics 2021 Sep 25;607:120975
International journal of pharmaceutics 2021 Sep 25;607:120975
A novel pyrrole-imidazole polyamide targets Aurora kinase A and suppresses tumor growth in vivo.
Li M, Lu D, Cheng Y, Wu C, Zhang J, Shi W, Ding Z, Li Y, Cheng B, Lin X, Shao X, Li H, Fang L, Liu K, Su W
Biochemical and biophysical research communications 2021 Sep 24;571:167-173
Biochemical and biophysical research communications 2021 Sep 24;571:167-173
Metabolic nuclear receptors coordinate energy metabolism to regulate Sox9(+) hepatocyte fate.
Liu S, Qin D, Yan Y, Wu J, Meng L, Huang W, Wang L, Chen X, Zhang L
iScience 2021 Sep 24;24(9):103003
iScience 2021 Sep 24;24(9):103003
Costunolide Loaded in pH-Responsive Mesoporous Silica Nanoparticles for Increased Stability and an Enhanced Anti-Fibrotic Effect.
Niu X, Wang X, Niu B, Meng Y, He H, Wang Y, Li G
Pharmaceuticals (Basel, Switzerland) 2021 Sep 23;14(10)
Pharmaceuticals (Basel, Switzerland) 2021 Sep 23;14(10)
Nuclear speckle specific hnRNP D-like prevents age- and AD-related cognitive decline by modulating RNA splicing.
Zhang Q, Zhang J, Ye J, Li X, Liu H, Ma X, Wang C, He K, Zhang W, Yuan J, Zhao Y, Xu H, Liu Q
Molecular neurodegeneration 2021 Sep 22;16(1):66
Molecular neurodegeneration 2021 Sep 22;16(1):66
Xenon Nanobubbles for the Image-Guided Preemptive Treatment of Acute Ischemic Stroke via Neuroprotection and Microcirculatory Restoration.
Jin J, Li M, Li J, Li B, Duan L, Yang F, Gu N
ACS applied materials & interfaces 2021 Sep 22;13(37):43880-43891
ACS applied materials & interfaces 2021 Sep 22;13(37):43880-43891
CD36 and DGAT2 facilitate the lipid-lowering effect of chitooligosaccharides via fatty acid intake and triglyceride synthesis signaling.
Shen X, Liang X, Ji X, You J, Zhuang X, Song Y, Yin H, Zhao M, Zhao L
Food & function 2021 Sep 20;12(18):8681-8693
Food & function 2021 Sep 20;12(18):8681-8693
Isonicotinylation is a histone mark induced by the anti-tuberculosis first-line drug isoniazid.
Jiang Y, Li Y, Liu C, Zhang L, Lv D, Weng Y, Cheng Z, Chen X, Zhan J, Zhang H
Nature communications 2021 Sep 20;12(1):5548
Nature communications 2021 Sep 20;12(1):5548
Deletion of phosphatidylserine flippase β-subunit Tmem30a in satellite cells leads to delayed skeletal muscle regeneration.
Sun KX, Jiang XY, Li X, Su YJ, Wang JL, Zhang L, Yang YM, Zhu XJ
Zoological research 2021 Sep 18;42(5):650-659
Zoological research 2021 Sep 18;42(5):650-659
RIOK2 Inhibitor NSC139021 Exerts Anti-Tumor Effects on Glioblastoma via Inducing Skp2-Mediated Cell Cycle Arrest and Apoptosis.
Yu M, Hu X, Yan J, Wang Y, Lu F, Chang J
Biomedicines 2021 Sep 17;9(9)
Biomedicines 2021 Sep 17;9(9)
Lactobacillus johnsonii L531 Alleviates the Damage Caused by Salmonella Typhimurium via Inhibiting TLR4, NF-κB, and NLRP3 Inflammasome Signaling Pathways.
Chen S, Li Y, Chu B, Yuan L, Liu N, Zhu Y, Wang J
Microorganisms 2021 Sep 17;9(9)
Microorganisms 2021 Sep 17;9(9)
MYO10 drives genomic instability and inflammation in cancer.
Mayca Pozo F, Geng X, Tamagno I, Jackson MW, Heimsath EG, Hammer JA, Cheney RE, Zhang Y
Science advances 2021 Sep 17;7(38):eabg6908
Science advances 2021 Sep 17;7(38):eabg6908
Isopsoralen ameliorates rheumatoid arthritis by targeting MIF.
Han Y, Wang J, Li S, Li Y, Zhang Y, Zhang R, Zhang Y, Fan H, Shi H, Pan J, Song G, Ge L, Wang L
Arthritis research & therapy 2021 Sep 17;23(1):243
Arthritis research & therapy 2021 Sep 17;23(1):243
MicroRNA-550a-3-5p controls the brain metastasis of lung cancer by directly targeting YAP1.
Wei L, Wang G, Yang C, Zhang Y, Chen Y, Zhong C, Li Q
Cancer cell international 2021 Sep 16;21(1):491
Cancer cell international 2021 Sep 16;21(1):491
EETs/sEHi alleviates nociception by blocking the crosslink between endoplasmic reticulum stress and neuroinflammation in a central poststroke pain model.
Liu T, Li T, Chen X, Li Z, Feng M, Yao W, Wan L, Zhang C, Zhang Y
Journal of neuroinflammation 2021 Sep 16;18(1):211
Journal of neuroinflammation 2021 Sep 16;18(1):211
PRMT5 regulates cell pyroptosis by silencing CASP1 in multiple myeloma.
Xia T, Liu M, Zhao Q, Ouyang J, Xu P, Chen B
Cell death & disease 2021 Sep 16;12(10):851
Cell death & disease 2021 Sep 16;12(10):851
Latcripin-7A from Lentinula edodes C(91-3) induces apoptosis, autophagy, and cell cycle arrest at G1 phase in human gastric cancer cells via inhibiting PI3K/Akt/mTOR signaling.
Din SRU, Nisar MA, Ramzan MN, Saleem MZ, Ghayas H, Ahmad B, Batool S, Kifayat K, Guo X, Huang M, Zhong M
European journal of pharmacology 2021 Sep 15;907:174305
European journal of pharmacology 2021 Sep 15;907:174305
Round Scad-Derived Octapeptide WCPFSRSF Confers Neuroprotection by Regulating Akt/Nrf2/NFκB Signaling.
Zhang Q, Su G, Yang Q, Wei Z, Wang J, Zheng L, Zhao M
Journal of agricultural and food chemistry 2021 Sep 15;69(36):10606-10616
Journal of agricultural and food chemistry 2021 Sep 15;69(36):10606-10616
The protection of selenium against cadmium-induced mitophagy via modulating nuclear xenobiotic receptors response and oxidative stress in the liver of rabbits.
Zhang L, Yang F, Li Y, Cao H, Huang A, Zhuang Y, Zhang C, Hu G, Mao Y, Luo J, Xing C
Environmental pollution (Barking, Essex : 1987) 2021 Sep 15;285:117301
Environmental pollution (Barking, Essex : 1987) 2021 Sep 15;285:117301
Co-exposure to BPA and DEHP enhances susceptibility of mammary tumors via up-regulating Esr1/HDAC6 pathway in female rats.
Zhang X, Cheng C, Zhang G, Xiao M, Li L, Wu S, Lu X
Ecotoxicology and environmental safety 2021 Sep 15;221:112453
Ecotoxicology and environmental safety 2021 Sep 15;221:112453
PM2.5-induced lung injury is attenuated in macrophage-specific NLRP3 deficient mice.
Xiong R, Jiang W, Li N, Liu B, He R, Wang B, Geng Q
Ecotoxicology and environmental safety 2021 Sep 15;221:112433
Ecotoxicology and environmental safety 2021 Sep 15;221:112433
Physiologically detectable bisphenol A impairs human sperm functions by reducing protein-tyrosine phosphorylation.
Li N, Kang H, Peng Z, Wang HF, Weng SQ, Zeng XH
Ecotoxicology and environmental safety 2021 Sep 15;221:112418
Ecotoxicology and environmental safety 2021 Sep 15;221:112418
Sigma-1 receptor regulates mitophagy in dopaminergic neurons and contributes to dopaminergic protection.
Wang M, Wan C, He T, Han C, Zhu K, Waddington JL, Zhen X
Neuropharmacology 2021 Sep 15;196:108360
Neuropharmacology 2021 Sep 15;196:108360
Scoparone inhibits pancreatic cancer through PI3K/Akt signaling pathway.
Li N, Yang F, Liu DY, Guo JT, Ge N, Sun SY
World journal of gastrointestinal oncology 2021 Sep 15;13(9):1164-1183
World journal of gastrointestinal oncology 2021 Sep 15;13(9):1164-1183
Quercitrin Rapidly Alleviated Depression-like Behaviors in Lipopolysaccharide-Treated Mice: The Involvement of PI3K/AKT/NF-κB Signaling Suppression and CREB/BDNF Signaling Restoration in the Hippocampus.
Sun Y, Zhang H, Wu Z, Yu X, Yin Y, Qian S, Wang Z, Huang J, Wang W, Liu T, Xue W, Chen G
ACS chemical neuroscience 2021 Sep 15;12(18):3387-3396
ACS chemical neuroscience 2021 Sep 15;12(18):3387-3396
Circular RNA ZNF609 enhances proliferation and glycolysis during glioma progression by miR-378b/SLC2A1 axis.
Zhao Z, Li G, Han Y, Li Y, Ji Z, Guo R, Yu X
Aging 2021 Sep 14;13(17):21122-21133
Aging 2021 Sep 14;13(17):21122-21133
Protective Effects and Mechanisms of Procyanidins on Parkinson's Disease In Vivo and In Vitro.
Chen J, Chen Y, Zheng Y, Zhao J, Yu H, Zhu J, Li D
Molecules (Basel, Switzerland) 2021 Sep 13;26(18)
Molecules (Basel, Switzerland) 2021 Sep 13;26(18)
Genome-wide mRNA profiling identifies the NRF2-regulated lymphocyte oxidative stress status in patients with silicosis.
Zhao Y, Xu G, Li H, Chang M, Xiong C, Tao Y, Guan Y, Li Y, Yao S
Journal of occupational medicine and toxicology (London, England) 2021 Sep 13;16(1):40
Journal of occupational medicine and toxicology (London, England) 2021 Sep 13;16(1):40
TNFSF9 promotes metastasis of pancreatic cancer through Wnt/Snail signaling and M2 polarization of macrophages.
Wu J, Wang Y, Yang Y, Liu F, Chen J, Jiang Z, Jiang Z
Aging 2021 Sep 13;13(17):21571-21586
Aging 2021 Sep 13;13(17):21571-21586
LPCAT1 reprogramming cholesterol metabolism promotes the progression of esophageal squamous cell carcinoma.
Tao M, Luo J, Gu T, Yu X, Song Z, Jun Y, Gu H, Han K, Huang X, Yu W, Sun S, Zhang Z, Liu L, Chen X, Zhang L, Luo C, Wang Q
Cell death & disease 2021 Sep 13;12(9):845
Cell death & disease 2021 Sep 13;12(9):845
Hypoxia regulates overall mRNA homeostasis by inducing Met(1)-linked linear ubiquitination of AGO2 in cancer cells.
Zhang H, Zhao X, Guo Y, Chen R, He J, Li L, Qiang Z, Yang Q, Liu X, Huang C, Lu R, Fang J, Cao Y, Huang J, Wang Y, Huang J, Chen GQ, Cheng J, Yu J
Nature communications 2021 Sep 13;12(1):5416
Nature communications 2021 Sep 13;12(1):5416
Ketamine ameliorates depressive-like behaviors in mice through increasing glucose uptake regulated by the ERK/GLUT3 signaling pathway.
Ouyang X, Wang Z, Luo M, Wang M, Liu X, Chen J, Feng J, Jia J, Wang X
Scientific reports 2021 Sep 13;11(1):18181
Scientific reports 2021 Sep 13;11(1):18181
2,5-dimethyl celecoxib induces apoptosis and autophagy via activation of ROS/JNK axis in nasopharyngeal carcinoma cells.
Tan T, Fu X, Qu J, Zhang M, Chen H, Wang Y, Wang B, Li J, Liu J, Liu P
Aging 2021 Sep 12;13(17):21483-21496
Aging 2021 Sep 12;13(17):21483-21496
A dual-role of SARS-CoV-2 nucleocapsid protein in regulating innate immune response.
Zhao Y, Sui L, Wu P, Wang W, Wang Z, Yu Y, Hou Z, Tan G, Liu Q, Wang G
Signal transduction and targeted therapy 2021 Sep 1;6(1):331
Signal transduction and targeted therapy 2021 Sep 1;6(1):331
MIER3 induces epithelial-mesenchymal transition and promotes breast cancer cell aggressiveness via forming a co-repressor complex with HDAC1/HDAC2/Snail.
Huang W, Chen J, Liu X, Liu X, Duan S, Chen L, Liu X, Lan J, Zou Y, Guo D, Zhou J
Experimental cell research 2021 Sep 1;406(1):112722
Experimental cell research 2021 Sep 1;406(1):112722
Differential expression of microRNAs in human endometrium after implantation of an intrauterine contraceptive device containing copper.
Fan X, Huang J, Xu C, Bao M, Xia W, Zhu C
Molecular human reproduction 2021 Sep 1;27(9)
Molecular human reproduction 2021 Sep 1;27(9)
Formosanin C attenuates lipopolysaccharide-induced inflammation through nuclear factor-κB inhibition in macrophages.
Yin L, Shi C, Zhang Z, Wang W, Li M
The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology 2021 Sep 1;25(5):395-401
The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology 2021 Sep 1;25(5):395-401
A general role for TANGO1, encoded by MIA3, in secretory pathway organization and function.
McCaughey J, Stevenson NL, Mantell JM, Neal CR, Paterson A, Heesom K, Stephens DJ
Journal of cell science 2021 Sep 1;134(17)
Journal of cell science 2021 Sep 1;134(17)
CLEC5A knockdown protects against cardiac dysfunction after myocardial infarction by suppressing macrophage polarization, NLRP3 inflammasome activation, and pyroptosis.
Wang X, Hu Y, Wang Y, Shen D, Tao G
Biochemistry and cell biology = Biochimie et biologie cellulaire 2021 Oct;99(5):655-665
Biochemistry and cell biology = Biochimie et biologie cellulaire 2021 Oct;99(5):655-665
Inhibition of YAP activation attenuates renal injury and fibrosis in angiotensin II hypertensive mice.
Zhang J, Xu Q, Ren F, Liu Y, Cai R, Yao Y, Zhou MS
Canadian journal of physiology and pharmacology 2021 Oct;99(10):1000-1006
Canadian journal of physiology and pharmacology 2021 Oct;99(10):1000-1006
Iguratimod decreases bleomycin-induced pulmonary fibrosis in association with inhibition of TNF-α in mice.
Shao S, Qu Z, Liang Y, Xu Y, Zhou D, Li D, Zhang Y, Yin S
International immunopharmacology 2021 Oct;99:107936
International immunopharmacology 2021 Oct;99:107936
A botanical dietary supplement from white peony and licorice attenuates nonalcoholic fatty liver disease by modulating gut microbiota and reducing inflammation.
Chen L, Kan J, Zheng N, Li B, Hong Y, Yan J, Tao X, Wu G, Ma J, Zhu W, Sheng L, Chen L, Li B, Zhong J, Du J, Li H
Phytomedicine : international journal of phytotherapy and phytopharmacology 2021 Oct;91:153693
Phytomedicine : international journal of phytotherapy and phytopharmacology 2021 Oct;91:153693
USP41 promotes breast cancer via regulating RACK1.
Huang M, Xiao J, Yan C, Wang T, Ling R
Annals of translational medicine 2021 Oct;9(20):1566
Annals of translational medicine 2021 Oct;9(20):1566
MYO1B enhances colorectal cancer metastasis by promoting the F-actin rearrangement and focal adhesion assembly via RhoA/ROCK/FAK signaling.
Xie L, Huang H, Zheng Z, Yang Q, Wang S, Chen Y, Yu J, Cui C
Annals of translational medicine 2021 Oct;9(20):1543
Annals of translational medicine 2021 Oct;9(20):1543
MET overexpression contributes to STAT4-PD-L1 signaling activation associated with tumor-associated, macrophages-mediated immunosuppression in primary glioblastomas.
Wang QW, Sun LH, Zhang Y, Wang Z, Zhao Z, Wang ZL, Wang KY, Li GZ, Xu JB, Ren CY, Ma WP, Wang HJ, Li SW, Zhu YJ, Jiang T, Bao ZS
Journal for immunotherapy of cancer 2021 Oct;9(10)
Journal for immunotherapy of cancer 2021 Oct;9(10)
Concentrated growth factor regulates the macrophage-mediated immune response.
Luo H, Liu W, Zhou Y, Jiang X, Liu Y, Yang Q, Shao L
Regenerative biomaterials 2021 Oct;8(6):rbab049
Regenerative biomaterials 2021 Oct;8(6):rbab049
YAP drives fate conversion and chemoresistance of small cell lung cancer.
Wu Q, Guo J, Liu Y, Zheng Q, Li X, Wu C, Fang D, Chen X, Ma L, Xu P, Xu X, Liao C, Wu M, Shen L, Song H
Science advances 2021 Oct;7(40):eabg1850
Science advances 2021 Oct;7(40):eabg1850
Immutol regulates CD4(+)Tregs, CD8(+)Tregs and pDCs via IDO signaling pathway to induce immune tolerance in rat heart allograft transplant.
Yang L, Ma J, He Q, Li X
Transplant immunology 2021 Oct;68:101393
Transplant immunology 2021 Oct;68:101393
Distinct pathogenic mechanisms of various RARS1 mutations in Pelizaeus-Merzbacher-like disease.
Li G, Eriani G, Wang ED, Zhou XL
Science China. Life sciences 2021 Oct;64(10):1645-1660
Science China. Life sciences 2021 Oct;64(10):1645-1660
Establishment of a second generation homozygous CRISPRa human induced pluripotent stem cell (hiPSC) line for enhanced levels of endogenous gene activation.
Schoger E, Zimmermann WH, Cyganek L, Zelarayán LC
Stem cell research 2021 Oct;56:102518
Stem cell research 2021 Oct;56:102518
Serine/threonine kinase 17b (STK17B) signalling regulates Purkinje cell dendritic development and is altered in multiple spinocerebellar ataxias.
Wu QW, Kapfhammer JP
The European journal of neuroscience 2021 Oct;54(7):6673-6684
The European journal of neuroscience 2021 Oct;54(7):6673-6684
ErbB4 mediates amyloid β-induced neurotoxicity through JNK/tau pathway activation: Implications for Alzheimer's disease.
Zhang H, Zhang L, Zhou D, Li H, Xu Y
The Journal of comparative neurology 2021 Oct;529(15):3497-3512
The Journal of comparative neurology 2021 Oct;529(15):3497-3512
Functional expression of TRPA1 channel, TRPV1 channel and TMEM100 in human odontoblasts.
Liu Y, Wang Y, Lou Y, Tian W, Que K
Journal of molecular histology 2021 Oct;52(5):1105-1114
Journal of molecular histology 2021 Oct;52(5):1105-1114
GFI1 promotes the proliferation and migration of esophageal squamous cell carcinoma cells through the inhibition of SOCS1 expression.
Huang Y, Ruan R, Fang Y, Wu K, Yao L, Zhang R, He W
International journal of molecular medicine 2021 Oct;48(4)
International journal of molecular medicine 2021 Oct;48(4)
Lactate and glutamine support NADPH generation in cancer cells under glucose deprived conditions.
Ying M, You D, Zhu X, Cai L, Zeng S, Hu X
Redox biology 2021 Oct;46:102065
Redox biology 2021 Oct;46:102065
Mono-macrophage-Derived MANF Alleviates Bacterial Myocarditis by Inhibiting NF-kappaB Activation and Myocardial Inflammation.
Wang C, Bao Q, Hou C, Sun M, Song X, Cao S, Wang X, Shen Q, Zhao Y, Wang D
Inflammation 2021 Oct;44(5):1916-1926
Inflammation 2021 Oct;44(5):1916-1926
Cystatin F acts as a mediator of immune suppression in glioblastoma.
Senjor E, Perišić Nanut M, Breznik B, Mitrović A, Mlakar J, Rotter A, Porčnik A, Lah Turnšek T, Kos J
Cellular oncology (Dordrecht, Netherlands) 2021 Oct;44(5):1051-1063
Cellular oncology (Dordrecht, Netherlands) 2021 Oct;44(5):1051-1063
Gossypol, a novel modulator of VCP, induces autophagic degradation of mutant huntingtin by promoting the formation of VCP/p97-LC3-mHTT complex.
Li XJ, Zhang YY, Fu YH, Zhang H, Li HX, Li QF, Li HL, Tan RK, Jiang CX, Jiang W, Li ZX, Luo C, Lu BX, Dang YJ
Acta pharmacologica Sinica 2021 Oct;42(10):1556-1566
Acta pharmacologica Sinica 2021 Oct;42(10):1556-1566
Nicotinamide phosphoribosyltransferase inhibitor ameliorates mouse aging-induced cognitive impairment.
Zeng M, Wei TF, Chen C, Shen C, Gao TY, Xie X, Wu M, Lu YB, Zhang WP
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2021 Oct;41(10):2510-2523
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2021 Oct;41(10):2510-2523
High-content screening of diterpenoids from Isodon species as autophagy modulators and the functional study of their antiviral activities.
Huang L, Fu Q, Dai JM, Yan BC, Wang D, Puno PT, Yue J
Cell biology and toxicology 2021 Oct;37(5):695-713
Cell biology and toxicology 2021 Oct;37(5):695-713
Role of Intracellular Distribution of Feline and Bovine SAMHD1 Proteins in Lentiviral Restriction.
Wang C, Meng L, Wang J, Zhang K, Duan S, Ren P, Wei Y, Fu X, Yu B, Wu J, Yu X
Virologica Sinica 2021 Oct;36(5):981-996
Virologica Sinica 2021 Oct;36(5):981-996
SETD8 involved in the progression of inflammatory bowel disease via epigenetically regulating p62 expression.
Chen P, Zhu H, Mao Y, Zhuo M, Yu Y, Chen M, Zhao Q, Li L, Wu M, Ye M
Journal of gastroenterology and hepatology 2021 Oct;36(10):2850-2863
Journal of gastroenterology and hepatology 2021 Oct;36(10):2850-2863
Therapeutic potential of isobavachalcone, a natural flavonoid, in murine experimental colitis by inhibiting NF-κB p65.
Zhou Y, Zhong B, Min X, Hou Y, Lin L, Wu Q, Shi J, Chen X
Phytotherapy research : PTR 2021 Oct;35(10):5861-5870
Phytotherapy research : PTR 2021 Oct;35(10):5861-5870
Pericytes augment glioblastoma cell resistance to temozolomide through CCL5-CCR5 paracrine signaling.
Zhang XN, Yang KD, Chen C, He ZC, Wang QH, Feng H, Lv SQ, Wang Y, Mao M, Liu Q, Tan YY, Wang WY, Li TR, Che LR, Qin ZY, Wu LX, Luo M, Luo CH, Liu YQ, Yin W, Wang C, Guo HT, Li QR, Wang B, Chen W, Wang S, Shi Y, Bian XW, Ping YF
Cell research 2021 Oct;31(10):1072-1087
Cell research 2021 Oct;31(10):1072-1087
Bakuchiol ameliorates cerebral ischemia-reperfusion injury by modulating NLRP3 inflammasome and Nrf2 signaling.
Xu Y, Gao X, Wang L, Yang M, Xie R
Respiratory physiology & neurobiology 2021 Oct;292:103707
Respiratory physiology & neurobiology 2021 Oct;292:103707
Vitamin D decreases Porphyromonas gingivalis internalized into macrophages by promoting autophagy.
Niu L, Chen S, Yang X, Ma C, Pan C, Wang H, Li Q, Geng F, Tang X
Oral diseases 2021 Oct;27(7):1775-1788
Oral diseases 2021 Oct;27(7):1775-1788
High-Throughput Screening to Identify Small Molecules That Selectively Inhibit APOL1 Protein Level in Podocytes.
Choy J, Kan Y, Cifelli S, Johnson J, Chen M, Shiao LL, Zhou H, Previs S, Lei Y, Johnstone R, Liaw A, Saigal A, Hu L, Ramos R, Visconti R, McElroy WT, Kreamer A, Wildey MJ, Peier A, Shin MK, Imbriglio J, Ren Z, Hoek M, Weinglass A, Ai X
SLAS discovery : advancing life sciences R & D 2021 Oct;26(9):1225-1237
SLAS discovery : advancing life sciences R & D 2021 Oct;26(9):1225-1237
Oridonin prevents oxidative stress-induced endothelial injury via promoting Nrf-2 pathway in ischaemic stroke.
Li L, Cheng SQ, Guo W, Cai ZY, Sun YQ, Huang XX, Yang J, Ji J, Chen YY, Dong YF, Cheng H, Sun XL
Journal of cellular and molecular medicine 2021 Oct;25(20):9753-9766
Journal of cellular and molecular medicine 2021 Oct;25(20):9753-9766
Hydrogen sulphide reduced the accumulation of lipid droplets in cardiac tissues of db/db mice via Hrd1 S-sulfhydration.
Sun Y, Zhang L, Lu B, Wen J, Wang M, Zhang S, Li Q, Shu F, Lu F, Liu N, Peng S, Zhao Y, Dong S, Lu F, Zhang W, Wang Y
Journal of cellular and molecular medicine 2021 Oct;25(19):9154-9167
Journal of cellular and molecular medicine 2021 Oct;25(19):9154-9167
SPOP promotes CDCA5 degradation to regulate prostate cancer progression via the AKT pathway.
Luo Z, Wang J, Zhu Y, Sun X, He C, Cai M, Ma J, Wang Y, Han S
Neoplasia (New York, N.Y.) 2021 Oct;23(10):1037-1047
Neoplasia (New York, N.Y.) 2021 Oct;23(10):1037-1047
Knockdown of ALDH1A3 reduces breast cancer stem cell marker CD44 via the miR-7-TGFBR2-Smad3-CD44 regulatory axis.
Pan M, Li M, Guo M, Zhou H, Xu H, Zhao F, Mei F, Xue R, Dou J
Experimental and therapeutic medicine 2021 Oct;22(4):1093
Experimental and therapeutic medicine 2021 Oct;22(4):1093
Establishment of incontinence-associated dermatitis rat models and assessment of the therapeutic effects of zinc oxide, painless skin protective film and silicone dressing.
Chen G, Huang L, Chen Y, Zheng S, Zhu L, Ding M
Experimental and therapeutic medicine 2021 Oct;22(4):1058
Experimental and therapeutic medicine 2021 Oct;22(4):1058
The adjuvanticity of manganese for microbial vaccines via activating the IRF5 signaling pathway.
Cui C, Wang S, Lu W, Wang Y, Li J, Qu K, Yang M, Wang L, Yu Y
Biochemical pharmacology 2021 Oct;192:114720
Biochemical pharmacology 2021 Oct;192:114720
PPARα agonist WY-14,643 induces adipose atrophy and fails to blunt chronic ethanol-induced hepatic fat accumulation in mice lacking adipose FGFR1.
Xu Y, Denning KL, Lu Y
Biochemical pharmacology 2021 Oct;192:114678
Biochemical pharmacology 2021 Oct;192:114678
Nestin Is Required for Spindle Assembly and Cell-Cycle Progression in Glioblastoma Cells.
Wang Q, Wu H, Hu J, Fu H, Qu Y, Yang Y, Cai KQ, Efimov A, Wu M, Yen T, Wang Y, Yang ZJ
Molecular cancer research : MCR 2021 Oct;19(10):1651-1665
Molecular cancer research : MCR 2021 Oct;19(10):1651-1665
Membrane-Associated RING-CH 8 Functions as a Novel PD-L1 E3 Ligase to Mediate PD-L1 Degradation Induced by EGFR Inhibitors.
Qian G, Guo J, Vallega KA, Hu C, Chen Z, Deng Y, Wang Q, Fan S, Ramalingam SS, Owonikoko TK, Wei W, Sun SY
Molecular cancer research : MCR 2021 Oct;19(10):1622-1634
Molecular cancer research : MCR 2021 Oct;19(10):1622-1634
4,4'-Dimethoxychalcone regulates redox homeostasis by targeting riboflavin metabolism in Parkinson's disease therapy.
Gong J, Zhang W, Ding L, Zhang M, Zheng S, Ma R, Tang J, Yi W, Xu H, Zhang Y
Free radical biology & medicine 2021 Oct;174:40-56
Free radical biology & medicine 2021 Oct;174:40-56
TSPAN1 promotes autophagy flux and mediates cooperation between WNT-CTNNB1 signaling and autophagy via the MIR454-FAM83A-TSPAN1 axis in pancreatic cancer.
Zhou C, Liang Y, Zhou L, Yan Y, Liu N, Zhang R, Huang Y, Wang M, Tang Y, Ali DW, Wang Y, Michalak M, Chen XZ, Tang J
Autophagy 2021 Oct;17(10):3175-3195
Autophagy 2021 Oct;17(10):3175-3195
Intrinsic bioactivity of black phosphorus nanomaterials on mitotic centrosome destabilization through suppression of PLK1 kinase.
Shao X, Ding Z, Zhou W, Li Y, Li Z, Cui H, Lin X, Cao G, Cheng B, Sun H, Li M, Liu K, Lu D, Geng S, Shi W, Zhang G, Song Q, Chen L, Wang G, Su W, Cai L, Fang L, Leong DT, Li Y, Yu XF, Li H
Nature nanotechnology 2021 Oct;16(10):1150-1160
Nature nanotechnology 2021 Oct;16(10):1150-1160
Inhibition of sEH via stabilizing the level of EETs alleviated Alzheimer's disease through GSK3β signaling pathway.
Sun CP, Zhang XY, Zhou JJ, Huo XK, Yu ZL, Morisseau C, Hammock BD, Ma XC
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2021 Oct;156:112516
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2021 Oct;156:112516
Salidroside alleviates taurolithocholic acid 3-sulfate-induced AR42J cell injury.
Qian J, Wang X, Weng W, Zhou G, Zhu S, Liu C
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Oct;142:112062
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Oct;142:112062
Inhibition of autophagy with Chloroquine enhanced apoptosis induced by 5-aminolevulinic acid-photodynamic therapy in secondary hyperparathyroidism primary cells and organoids.
Zeng L, Zou Q, Huang P, Xiong L, Cheng Y, Chen Q, Li Y, He H, Yi W, Wei W
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Oct;142:111994
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Oct;142:111994
Synergic radiosensitization of sinomenine hydrochloride and radioiodine on human papillary thyroid carcinoma cells.
Zhao A, Zhang J, Liu Y, Jia X, Lu X, Wang Q, Ji T, Yang L, Xue J, Gao R, Yu Y, Yang A
Translational oncology 2021 Oct;14(10):101172
Translational oncology 2021 Oct;14(10):101172
ATG16L2 overexpression is associated with a good prognosis in colorectal cancer.
Tang J, Wang D, Shen Y, Xue F
Journal of gastrointestinal oncology 2021 Oct;12(5):2192-2202
Journal of gastrointestinal oncology 2021 Oct;12(5):2192-2202
KIF2C: a novel link between Wnt/β-catenin and mTORC1 signaling in the pathogenesis of hepatocellular carcinoma.
Wei S, Dai M, Zhang C, Teng K, Wang F, Li H, Sun W, Feng Z, Kang T, Guan X, Xu R, Cai M, Xie D
Protein & cell 2021 Oct;12(10):788-809
Protein & cell 2021 Oct;12(10):788-809
Travelling ultrasound promotes vasculogenesis of three-dimensional-monocultured human umbilical vein endothelial cells.
Imashiro C, Azuma T, Itai S, Kuribara T, Totani K, Onoe H, Takemura K
Biotechnology and bioengineering 2021 Oct;118(10):3760-3769
Biotechnology and bioengineering 2021 Oct;118(10):3760-3769
Transcription factor POU4F2 promotes colorectal cancer cell migration and invasion through hedgehog-mediated epithelial-mesenchymal transition.
Guo K, Wang P, Zhang L, Zhou Y, Dai X, Yan Y, Chen Y, Wasan HS, Yu J, Ruan S, Sun L
Cancer science 2021 Oct;112(10):4176-4186
Cancer science 2021 Oct;112(10):4176-4186
PD0325901, an ERK inhibitor, enhances the efficacy of PD-1 inhibitor in non-small cell lung carcinoma.
Luo M, Xia Y, Wang F, Zhang H, Su D, Su C, Yang C, Wu S, An S, Lin S, Fu L
Acta pharmaceutica Sinica. B 2021 Oct;11(10):3120-3133
Acta pharmaceutica Sinica. B 2021 Oct;11(10):3120-3133
Cordycepin inhibits cell senescence by ameliorating lysosomal dysfunction and inducing autophagy through the AMPK and mTOR-p70S6K pathway.
Zuo SQ, Li C, Liu YL, Tan YH, Wan X, Xu T, Li Q, Wang L, Wu YL, Deng FM, Tang B
FEBS open bio 2021 Oct;11(10):2705-2714
FEBS open bio 2021 Oct;11(10):2705-2714
NLRX1 can counteract innate immune response induced by an external stimulus favoring HBV infection by competitive inhibition of MAVS-RLRs signaling in HepG2-NTCP cells.
Jiao Q, Xu W, Guo X, Liu H, Liao B, Zhu X, Chen C, Yang F, Wu L, Xie C, Peng L
Science progress 2021 Oct;104(4):368504211058036
Science progress 2021 Oct;104(4):368504211058036
Curcumin attenuates Adriamycin-resistance of acute myeloid leukemia by inhibiting the lncRNA HOTAIR/miR-20a-5p/WT1 axis.
Liu JM, Li M, Luo W, Sun HB
Laboratory investigation; a journal of technical methods and pathology 2021 Oct;101(10):1308-1317
Laboratory investigation; a journal of technical methods and pathology 2021 Oct;101(10):1308-1317
FNDC4 acts as an extracellular factor to promote the invasiveness of hepatocellular carcinoma partly via the PI3K/Akt signalling pathway.
Wang B, Zheng B, Lu Y, Huang D, Liu J, Song J, Zheng S
Cancer medicine 2021 Oct;10(20):7242-7252
Cancer medicine 2021 Oct;10(20):7242-7252
Myosin 1f-mediated activation of microglia contributes to the photoreceptor degeneration in a mouse model of retinal detachment.
Wang Y, Zhao X, Gao M, Wan X, Guo Y, Qu Y, Chen Y, Li T, Liu H, Jiang M, Wang F, Sun X
Cell death & disease 2021 Oct 9;12(10):926
Cell death & disease 2021 Oct 9;12(10):926
Serum Level of Tumor-Overexpressed AGR2 Is Significantly Associated with Unfavorable Prognosis of Canine Malignant Mammary Tumors.
Yuan SH, Chang SC, Huang Y, Liu HP
Animals : an open access journal from MDPI 2021 Oct 9;11(10)
Animals : an open access journal from MDPI 2021 Oct 9;11(10)
Metformin accelerates zebrafish heart regeneration by inducing autophagy.
Xie F, Xu S, Lu Y, Wong KF, Sun L, Hasan KMM, Ma ACH, Tse G, Manno SHC, Tian L, Yue J, Cheng SH
NPJ Regenerative medicine 2021 Oct 8;6(1):62
NPJ Regenerative medicine 2021 Oct 8;6(1):62
Extracellular AGR2 activates neighboring fibroblasts through endocytosis and direct binding to β-catenin that requires AGR2 dimerization and adhesion domains.
Merugu SB, Zhou B, Mangukiya HB, Negi H, Ghulam R, Roy D, Qudsia S, Wang Z, Mashausi DS, Yunus FU, Liu GS, Li D
Biochemical and biophysical research communications 2021 Oct 8;573:86-92
Biochemical and biophysical research communications 2021 Oct 8;573:86-92
Adenylyl cyclase 3 regulates osteocyte mechanotransduction and primary cilium.
Duffy MP, Sup ME, Guo XE
Biochemical and biophysical research communications 2021 Oct 8;573:145-150
Biochemical and biophysical research communications 2021 Oct 8;573:145-150
Targeting MUS81 promotes the anticancer effect of WEE1 inhibitor and immune checkpoint blocking combination therapy via activating cGAS/STING signaling in gastric cancer cells.
Li C, Shen Q, Zhang P, Wang T, Liu W, Li R, Ma X, Zeng X, Yin Y, Tao K
Journal of experimental & clinical cancer research : CR 2021 Oct 8;40(1):315
Journal of experimental & clinical cancer research : CR 2021 Oct 8;40(1):315
Inhibition of immunoproteasome subunit low molecular mass polypeptide 7 with ONX-0914 improves hypoxic-ischemic brain damage via PI3K/Akt signaling.
Zhou Y, Gou Z, Huang L, Fan Y, Zhang F, Lu L
Neuroreport 2021 Oct 6;32(14):1206-1215
Neuroreport 2021 Oct 6;32(14):1206-1215
Thymosin beta 4 alleviates non-alcoholic fatty liver by inhibiting ferroptosis via up-regulation of GPX4.
Zhu Z, Zhang Y, Huang X, Can L, Zhao X, Wang Y, Xue J, Cheng M, Zhu L
European journal of pharmacology 2021 Oct 5;908:174351
European journal of pharmacology 2021 Oct 5;908:174351
CDC42EP3 is a key promoter involved in the development and progression of gastric cancer.
Chen W, Zhu Y, Zhang W, Zhang H, Zhou Y, Sun P, Wu G
Carcinogenesis 2021 Oct 5;42(9):1179-1188
Carcinogenesis 2021 Oct 5;42(9):1179-1188
Infantile spasms-linked Nedd4-2 mediates hippocampal plasticity and learning via cofilin signaling.
Lee KY, Zhu J, Cutia CA, Christian-Hinman CA, Rhodes JS, Tsai NP
EMBO reports 2021 Oct 5;22(10):e52645
EMBO reports 2021 Oct 5;22(10):e52645
Sesamol supplementation alleviates nonalcoholic steatohepatitis and atherosclerosis in high-fat, high carbohydrate and high-cholesterol diet-fed rats.
Yang Y, Qu Y, Lv X, Zhao R, Yu J, Hu S, Kang J, Zhang Y, Gong Y, Cui T, Zhang X, Yan Y
Food & function 2021 Oct 4;12(19):9347-9359
Food & function 2021 Oct 4;12(19):9347-9359
Cathepsin B Regulates Mice Granulosa Cells' Apoptosis and Proliferation In Vitro.
Chen C, Ahmad MJ, Ye T, Du C, Zhang X, Liang A, Yang L
International journal of molecular sciences 2021 Oct 31;22(21)
International journal of molecular sciences 2021 Oct 31;22(21)
Lipophagy deficiency exacerbates ectopic lipid accumulation and tubular cells injury in diabetic nephropathy.
Han Y, Xiong S, Zhao H, Yang S, Yang M, Zhu X, Jiang N, Xiong X, Gao P, Wei L, Xiao Y, Sun L
Cell death & disease 2021 Oct 30;12(11):1031
Cell death & disease 2021 Oct 30;12(11):1031
Jian-Pi-Yi-Shen formula enhances perindopril inhibition of chronic kidney disease progression by activation of SIRT3, modulation of mitochondrial dynamics, and antioxidant effects.
Liu X, Deng R, Wei X, Wang Y, Weng J, Lao Y, Lu J, Xiong G, Li S
Bioscience reports 2021 Oct 29;41(10)
Bioscience reports 2021 Oct 29;41(10)
AnnexinA7 promotes epithelial-mesenchymal transition by interacting with Sorcin and contributes to aggressiveness in hepatocellular carcinoma.
Ling F, Zhang H, Sun Y, Meng J, Sanches JGP, Huang H, Zhang Q, Yu X, Wang B, Hou L, Zhang J
Cell death & disease 2021 Oct 29;12(11):1018
Cell death & disease 2021 Oct 29;12(11):1018
Quantitatively mapping the interaction of HER2 and EGFR on cell membranes with peptide probes.
Yan Q, Cai M, Jing Y, Li H, Xu H, Sun J, Gao J, Wang H
Nanoscale 2021 Oct 28;13(41):17629-17637
Nanoscale 2021 Oct 28;13(41):17629-17637
RCAN1.4 attenuates renal fibrosis through inhibiting calcineurin-mediated nuclear translocation of NFAT2.
Zhang J, Chen H, Weng X, Liu H, Chen Z, Huang Q, Wang L, Liu X
Cell death discovery 2021 Oct 27;7(1):317
Cell death discovery 2021 Oct 27;7(1):317
Chitosan oligosaccharides packaged into rat adipose mesenchymal stem cells-derived extracellular vesicles facilitating cartilage injury repair and alleviating osteoarthritis.
Li S, Liu J, Liu S, Jiao W, Wang X
Journal of nanobiotechnology 2021 Oct 26;19(1):343
Journal of nanobiotechnology 2021 Oct 26;19(1):343
Clonal hematopoiesis with JAK2V617F promotes pulmonary hypertension with ALK1 upregulation in lung neutrophils.
Kimishima Y, Misaka T, Yokokawa T, Wada K, Ueda K, Sugimoto K, Minakawa K, Nakazato K, Ishida T, Oshima M, Koide S, Shide K, Shimoda K, Iwama A, Ikeda K, Takeishi Y
Nature communications 2021 Oct 26;12(1):6177
Nature communications 2021 Oct 26;12(1):6177
Identification of novel key genes associated with the metastasis of prostate cancer based on bioinformatics prediction and validation.
Song F, Zhang Y, Pan Z, Hu X, Yi Y, Zheng X, Wei H, Huang P
Cancer cell international 2021 Oct 25;21(1):559
Cancer cell international 2021 Oct 25;21(1):559
Lnc-DC promotes estrogen independent growth and tamoxifen resistance in breast cancer.
Peng WX, Koirala P, Zhou H, Jiang J, Zhang Z, Yang L, Mo YY
Cell death & disease 2021 Oct 25;12(11):1000
Cell death & disease 2021 Oct 25;12(11):1000
Crocetin suppresses angiogenesis and metastasis through inhibiting sonic hedgehog signaling pathway in gastric cancer.
Zang M, Hou J, Huang Y, Wang J, Ding X, Zhang B, Wang Y, Xuan Y, Zhou Y
Biochemical and biophysical research communications 2021 Oct 22;576:86-92
Biochemical and biophysical research communications 2021 Oct 22;576:86-92
Circular RNA circUBE2J2 acts as the sponge of microRNA-370-5P to suppress hepatocellular carcinoma progression.
Zhang L, Liu Y, Tao H, Zhu H, Pan Y, Li P, Liang H, Zhang B, Song J
Cell death & disease 2021 Oct 22;12(11):985
Cell death & disease 2021 Oct 22;12(11):985
CHD8 safeguards early neuroectoderm differentiation in human ESCs and protects from apoptosis during neurogenesis.
Ding S, Lan X, Meng Y, Yan C, Li M, Li X, Chen J, Jiang W
Cell death & disease 2021 Oct 22;12(11):981
Cell death & disease 2021 Oct 22;12(11):981
Kinesin family member 2C promotes hepatocellular carcinoma growth and metastasis via activating MEK/ERK pathway.
Ding Q, Jiang C, Zhou Y, Duan J, Lai J, Jiang M, Lin D
Bioscience, biotechnology, and biochemistry 2021 Oct 21;85(11):2241-2249
Bioscience, biotechnology, and biochemistry 2021 Oct 21;85(11):2241-2249
FGGY carbohydrate kinase domain containing is expressed and alternatively spliced in skeletal muscle and attenuates MAP kinase and Akt signaling.
Smith AL, Gjoka E, Izhar M, Novo KJ, Mason BC, De Las Casas A, Waddell DS
Gene 2021 Oct 20;800:145836
Gene 2021 Oct 20;800:145836
TM7SF2 regulates cell proliferation and apoptosis by activation of C-Raf/ERK pathway in cervical cancer.
Xu Y, Chen X, Pan S, Wang ZW, Zhu X
Cell death discovery 2021 Oct 19;7(1):299
Cell death discovery 2021 Oct 19;7(1):299
Overexpression of FGF2 delays the progression of osteonecrosis of the femoral head activating the PI3K/Akt signaling pathway.
Lu P, Shen YM, Hua T, Pan T, Chen G, Dai T, Shi KQ
Journal of orthopaedic surgery and research 2021 Oct 18;16(1):613
Journal of orthopaedic surgery and research 2021 Oct 18;16(1):613
Palmitoylation targets the calcineurin phosphatase to the phosphatidylinositol 4-kinase complex at the plasma membrane.
Ulengin-Talkish I, Parson MAH, Jenkins ML, Roy J, Shih AZL, St-Denis N, Gulyas G, Balla T, Gingras AC, Várnai P, Conibear E, Burke JE, Cyert MS
Nature communications 2021 Oct 18;12(1):6064
Nature communications 2021 Oct 18;12(1):6064
Noncanonical Wnt5a signaling regulates tendon stem/progenitor cells senescence.
Chen M, Li Y, Xiao L, Dai G, Lu P, Rui Y
Stem cell research & therapy 2021 Oct 18;12(1):544
Stem cell research & therapy 2021 Oct 18;12(1):544
Human mesenchymal stem cells derived exosomes inhibit the growth of acute myeloid leukemia cells via regulating miR-23b-5p/TRIM14 pathway.
Cheng H, Ding J, Tang G, Huang A, Gao L, Yang J, Chen L
Molecular medicine (Cambridge, Mass.) 2021 Oct 16;27(1):128
Molecular medicine (Cambridge, Mass.) 2021 Oct 16;27(1):128
Stem Cell Factor SOX2 Confers Ferroptosis Resistance in Lung Cancer via Upregulation of SLC7A11.
Wang X, Chen Y, Wang X, Tian H, Wang Y, Jin J, Shan Z, Liu Y, Cai Z, Tong X, Luan Y, Tan X, Luan B, Ge X, Ji H, Jiang X, Wang P
Cancer research 2021 Oct 15;81(20):5217-5229
Cancer research 2021 Oct 15;81(20):5217-5229
INTS6 promotes colorectal cancer progression by activating of AKT and ERK signaling.
Ding X, Chen T, Shi Q, Nan P, Wang X, Xie D, Li J
Experimental cell research 2021 Oct 15;407(2):112826
Experimental cell research 2021 Oct 15;407(2):112826
T-lymphoma invasion and metastasis 1 promotes invadopodia formation and is regulated by the PI3K/Akt signaling pathway in hepatocellular carcinoma.
Wang B, Zheng B, Cao L, Liao K, Huang D, Zhang Y, Jiang Y, Zheng S
Experimental cell research 2021 Oct 15;407(2):112806
Experimental cell research 2021 Oct 15;407(2):112806
The expression of IFN-β is suppressed by the viral 3D polymerase via its impact on PGAM5 expression during enterovirus D68 infection.
Yang Z, Zheng H, Li H, Chen Y, Hou D, Fan Q, Song J, Guo L, Liu L
Virus research 2021 Oct 15;304:198549
Virus research 2021 Oct 15;304:198549
Design, synthesis, and biological evaluation of 2,4-diamino pyrimidine derivatives as potent FAK inhibitors with anti-cancer and anti-angiogenesis activities.
Wang S, Zhang RH, Zhang H, Wang YC, Yang D, Zhao YL, Yan GY, Xu GB, Guan HY, Zhou YH, Cui DB, Liu T, Li YJ, Liao SG, Zhou M
European journal of medicinal chemistry 2021 Oct 15;222:113573
European journal of medicinal chemistry 2021 Oct 15;222:113573
HBeAg mediates inflammatory functions of macrophages by TLR2 contributing to hepatic fibrosis.
Xie X, Lv H, Liu C, Su X, Yu Z, Song S, Bian H, Tian M, Qin C, Qi J, Zhu Q
BMC medicine 2021 Oct 15;19(1):247
BMC medicine 2021 Oct 15;19(1):247
SMAD2 regulates testicular development and testosterone synthesis in Hu sheep.
Yang H, Wan Z, Jin Y, Wang F, Zhang Y
Theriogenology 2021 Oct 15;174:139-148
Theriogenology 2021 Oct 15;174:139-148
The FOXM1/RNF26/p57 axis regulates the cell cycle to promote the aggressiveness of bladder cancer.
Yi L, Wang H, Li W, Ye K, Xiong W, Yu H, Jin X
Cell death & disease 2021 Oct 14;12(10):944
Cell death & disease 2021 Oct 14;12(10):944
Human m(6)A-mRNA and lncRNA epitranscriptomic microarray reveal function of RNA methylation in hemoglobin H-constant spring disease.
Ruan H, Yang F, Deng L, Yang D, Zhang X, Li X, Pang L
Scientific reports 2021 Oct 14;11(1):20478
Scientific reports 2021 Oct 14;11(1):20478
DLEU1 promotes oral squamous cell carcinoma progression by activating interferon-stimulated genes.
Hatanaka Y, Niinuma T, Kitajima H, Nishiyama K, Maruyama R, Ishiguro K, Toyota M, Yamamoto E, Kai M, Yorozu A, Sekiguchi S, Ogi K, Dehari H, Idogawa M, Sasaki Y, Tokino T, Miyazaki A, Suzuki H
Scientific reports 2021 Oct 14;11(1):20438
Scientific reports 2021 Oct 14;11(1):20438
17β-Estradiol Enhances Porcine Meiosis Resumption from Autophagy-Induced Gap Junction Intercellular Communications and Connexin 43 Phosphorylation via the MEK/ERK Signaling Pathway.
Duan J, Chen H, Li Y, Xu D, Li X, Zhang Z, Cheng J, Yang L, Li Q
Journal of agricultural and food chemistry 2021 Oct 13;69(40):11847-11855
Journal of agricultural and food chemistry 2021 Oct 13;69(40):11847-11855
The interaction of S100A16 and GRP78 actives endoplasmic reticulum stress-mediated through the IRE1α/XBP1 pathway in renal tubulointerstitial fibrosis.
Jin R, Zhao A, Han S, Zhang D, Sun H, Li M, Su D, Liang X
Cell death & disease 2021 Oct 13;12(10):942
Cell death & disease 2021 Oct 13;12(10):942
MINDY1 promotes breast cancer cell proliferation by stabilizing estrogen receptor α.
Tang J, Luo Y, Long G, Zhou L
Cell death & disease 2021 Oct 13;12(10):937
Cell death & disease 2021 Oct 13;12(10):937
Phase separation of Nur77 mediates celastrol-induced mitophagy by promoting the liquidity of p62/SQSTM1 condensates.
Peng SZ, Chen XH, Chen SJ, Zhang J, Wang CY, Liu WR, Zhang D, Su Y, Zhang XK
Nature communications 2021 Oct 13;12(1):5989
Nature communications 2021 Oct 13;12(1):5989
BRCA2 associates with MCM10 to suppress PRIMPOL-mediated repriming and single-stranded gap formation after DNA damage.
Kang Z, Fu P, Alcivar AL, Fu H, Redon C, Foo TK, Zuo Y, Ye C, Baxley R, Madireddy A, Buisson R, Bielinsky AK, Zou L, Shen Z, Aladjem MI, Xia B
Nature communications 2021 Oct 13;12(1):5966
Nature communications 2021 Oct 13;12(1):5966
Ordered assembly of the cytosolic RNA-sensing MDA5-MAVS signaling complex via binding to unanchored K63-linked poly-ubiquitin chains.
Song B, Chen Y, Liu X, Yuan F, Tan EYJ, Lei Y, Song N, Han Y, Pascal BD, Griffin PR, Luo C, Wu B, Luo D, Zheng J
Immunity 2021 Oct 12;54(10):2218-2230.e5
Immunity 2021 Oct 12;54(10):2218-2230.e5
Blockade of T helper 17 cell function ameliorates recurrent Clostridioides difficile infection in mice.
Wang S, Deng W, Li F, Chen YE, Wang PU
Acta biochimica et biophysica Sinica 2021 Oct 12;53(10):1290-1299
Acta biochimica et biophysica Sinica 2021 Oct 12;53(10):1290-1299
Analyzing the whole-transcriptome profiles of ncRNAs and predicting the competing endogenous RNA networks in cervical cancer cell lines with cisplatin resistance.
Lv H, Jin S, Zou B, Liang Y, Xie J, Wu S
Cancer cell international 2021 Oct 12;21(1):532
Cancer cell international 2021 Oct 12;21(1):532
FAM83A promotes proliferation and metastasis via Wnt/β-catenin signaling in head neck squamous cell carcinoma.
Ji H, Song H, Wang Z, Jiao P, Xu J, Li X, Du H, Wu H, Zhong Y
Journal of translational medicine 2021 Oct 12;19(1):423
Journal of translational medicine 2021 Oct 12;19(1):423
MiR-20a-5p overexpression prevented diabetic cardiomyopathy via inhibition of cardiomyocyte apoptosis, hypertrophy, fibrosis and JNK/NF-κB signalling pathway.
Liu X, Guo B, Zhang W, Ma B, Li Y
Journal of biochemistry 2021 Oct 12;170(3):349-362
Journal of biochemistry 2021 Oct 12;170(3):349-362
Vezatin regulates seizures by controlling AMPAR-mediated synaptic activity.
Wang Y, Yuan J, Yu X, Liu X, Tan C, Chen Y, Xu T
Cell death & disease 2021 Oct 12;12(10):936
Cell death & disease 2021 Oct 12;12(10):936
Inactivation of the CIC-DUX4 oncogene through P300/CBP inhibition, a therapeutic approach for CIC-DUX4 sarcoma.
Bosnakovski D, Ener ET, Cooper MS, Gearhart MD, Knights KA, Xu NC, Palumbo CA, Toso EA, Marsh GP, Maple HJ, Kyba M
Oncogenesis 2021 Oct 12;10(10):68
Oncogenesis 2021 Oct 12;10(10):68
ZFC3H1 prevents RNA trafficking into nuclear speckles through condensation.
Wang Y, Fan J, Wang J, Zhu Y, Xu L, Tong D, Cheng H
Nucleic acids research 2021 Oct 11;49(18):10630-10643
Nucleic acids research 2021 Oct 11;49(18):10630-10643
PCYT2 synthesizes CDP-glycerol in mammals and reduced PCYT2 enhances the expression of functionally glycosylated α-dystroglycan.
Imae R, Manya H, Tsumoto H, Miura Y, Endo T
Journal of biochemistry 2021 Oct 11;170(2):183-194
Journal of biochemistry 2021 Oct 11;170(2):183-194
Integrative epigenomic and high-throughput functional enhancer profiling reveals determinants of enhancer heterogeneity in gastric cancer.
Sheng T, Ho SWT, Ooi WF, Xu C, Xing M, Padmanabhan N, Huang KK, Ma L, Ray M, Guo YA, Sim NL, Anene-Nzelu CG, Chang MM, Razavi-Mohseni M, Beer MA, Foo RSY, Sundar R, Chan YH, Tan ALK, Ong X, Skanderup AJ, White KP, Jha S, Tan P
Genome medicine 2021 Oct 11;13(1):158
Genome medicine 2021 Oct 11;13(1):158
Cigarette smoking induces aberrant N(6)-methyladenosine of DAPK2 to promote non-small cell lung cancer progression by activating NF-κB pathway.
Jin M, Li G, Liu W, Wu X, Zhu J, Zhao D, Zeng Z, Xiong M, Song Y, He X, Zhang Q, Hu K
Cancer letters 2021 Oct 10;518:214-229
Cancer letters 2021 Oct 10;518:214-229
Autophagy-dependent ferroptosis contributes to cisplatin-induced hearing loss.
Jian B, Pang J, Xiong H, Zhang W, Zhan T, Su Z, Lin H, Zhang H, He W, Zheng Y
Toxicology letters 2021 Oct 10;350:249-260
Toxicology letters 2021 Oct 10;350:249-260
Hsa_circ_0011385 knockdown represses cell proliferation in hepatocellular carcinoma.
Ni C, Yang S, Ji Y, Duan Y, Yang W, Yang X, Li M, Xie J, Zhang C, Lu Y, Lu H
Cell death discovery 2021 Oct 1;7(1):270
Cell death discovery 2021 Oct 1;7(1):270
Comparative Proteomics of Rat Olfactory Bulb Reveal Insights into Susceptibility and Resiliency to Chronic-stress-induced Depression or Anxiety.
Liu D, Cai X, Wang L, Yi F, Liao W, Huang R, Fang C, Chen J, Zhou J
Neuroscience 2021 Oct 1;473:29-43
Neuroscience 2021 Oct 1;473:29-43
AGTR1 blocker attenuates activation of Tenon's capsule fibroblasts after glaucoma filtration surgery via the NF-κB signaling pathway.
Wang L, Li H, Zhang W, Ren M, Shao M, Wang J
Experimental cell research 2021 Oct 1;407(1):112786
Experimental cell research 2021 Oct 1;407(1):112786
A-24, a steroidal saponin from Allium chinense, induced apoptosis, autophagy and migration inhibition in p53 wild-type and p53-deficient gastric cancer cells.
Xu J, Wang Y, Wang Y, Wang Z, He X
Chemico-biological interactions 2021 Oct 1;348:109648
Chemico-biological interactions 2021 Oct 1;348:109648
Diabetic ferroptosis plays an important role in triggering on inflammation in diabetic wound.
Li S, Li Y, Wu Z, Wu Z, Fang H
American journal of physiology. Endocrinology and metabolism 2021 Oct 1;321(4):E509-E520
American journal of physiology. Endocrinology and metabolism 2021 Oct 1;321(4):E509-E520
Relationships between di-(2-ethylhexyl) phthalate exposure and lipid metabolism in adolescents: Human data and experimental rat model analyses.
Ding S, Qi W, Xu Q, Zhao T, Li X, Yin J, Zhang R, Huo C, Zhou L, Ye L
Environmental pollution (Barking, Essex : 1987) 2021 Oct 1;286:117570
Environmental pollution (Barking, Essex : 1987) 2021 Oct 1;286:117570
Circ-RNF13, as an oncogene, regulates malignant progression of HBV-associated hepatocellular carcinoma cells and HBV infection through ceRNA pathway of circ-RNF13/miR-424-5p/TGIF2.
Chen Y, Li S, Wei Y, Xu Z, Wu X
Bosnian journal of basic medical sciences 2021 Oct 1;21(5):555-568
Bosnian journal of basic medical sciences 2021 Oct 1;21(5):555-568
Flow cytometry allows rapid detection of protein aggregates in cellular and zebrafish models of spinocerebellar ataxia 3.
Robinson KJ, Tym MC, Hogan A, Watchon M, Yuan KC, Plenderleith SK, Don EK, Laird AS
Disease models & mechanisms 2021 Oct 1;14(10)
Disease models & mechanisms 2021 Oct 1;14(10)
Elevated β-secretase 1 expression mediates CD4(+) T cell dysfunction via PGE2 signalling in Alzheimer's disease.
Dai L, Wang Q, Lv X, Gao F, Chen Z, Shen Y
Brain, behavior, and immunity 2021 Nov;98:337-348
Brain, behavior, and immunity 2021 Nov;98:337-348
Yiqi-Huoxue granule promotes angiogenesis of ischemic myocardium through miR-126/PI3K/Akt axis in endothelial cells.
Gao H, Peng C, Wu L, Gao S, Wang Z, Dai L, Wu H
Phytomedicine : international journal of phytotherapy and phytopharmacology 2021 Nov;92:153713
Phytomedicine : international journal of phytotherapy and phytopharmacology 2021 Nov;92:153713
Long noncoding TMPO antisense RNA 1 promotes hepatocellular carcinoma proliferation and epithelial-mesenchymal transition by targeting the microRNA-126-3p/LRP6/β-catenin axis.
Huang W, Chen Q, Dai J, Zhang Y, Yi Y, Wei X
Annals of translational medicine 2021 Nov;9(22):1679
Annals of translational medicine 2021 Nov;9(22):1679
Botrychium schaffneri Underw. extract acts via DIABLO to induce apoptosis and inhibit proliferation of non-small cell lung carcinoma in vitro and in vivo.
Liu YJ, Zhang YW, Zheng SL, Zheng XC, Ding HY, Xin WX, Sun J, Li L, Huang P
Annals of translational medicine 2021 Nov;9(22):1676
Annals of translational medicine 2021 Nov;9(22):1676
Trimethylamine-N-oxide-stimulated hepatocyte-derived exosomes promote inflammation and endothelial dysfunction through nuclear factor-kappa B signaling.
Liu X, Shao Y, Tu J, Sun J, Li L, Tao J, Chen J
Annals of translational medicine 2021 Nov;9(22):1670
Annals of translational medicine 2021 Nov;9(22):1670
Human umbilical cord mesenchymal stem cells ameliorate acute liver failure by inhibiting apoptosis, inflammation and pyroptosis.
Liu M, He J, Zheng S, Zhang K, Ouyang Y, Zhang Y, Li C, Wu D
Annals of translational medicine 2021 Nov;9(21):1615
Annals of translational medicine 2021 Nov;9(21):1615
Switch receptor T3/28 improves long-term persistence and antitumor efficacy of CAR-T cells.
Zhao S, Wang C, Lu P, Lou Y, Liu H, Wang T, Yang S, Bao Z, Han L, Liang X, Ma C, Gao L
Journal for immunotherapy of cancer 2021 Nov;9(12)
Journal for immunotherapy of cancer 2021 Nov;9(12)
Circular RNA circZFPM2 promotes epithelial-mesenchymal transition in endometriosis by regulating miR-205-5p/ZEB1 signalling pathway.
Wang D, Cui L, Yang Q, Wang J
Cellular signalling 2021 Nov;87:110145
Cellular signalling 2021 Nov;87:110145
Decreased phosphorylation facilitates the degradation of the endogenous protective molecule c-Ski in vascular smooth muscle cells.
He W, Chen Z, Li H, Wu W, He P, Zhong D, Jiang Y, Cheng W, Xu Z, Li J
Cellular signalling 2021 Nov;87:110116
Cellular signalling 2021 Nov;87:110116
Neuroprotective effect of Na(+) /H(+) exchangers isoform-1 inactivation against 6-hydroxydopamine-induced mitochondrial dysfunction and neuronal apoptosis in Parkinson's disease models.
Xing R, Liu X, Tian B, Cheng Y, Li L
Drug development research 2021 Nov;82(7):969-979
Drug development research 2021 Nov;82(7):969-979
Long non-coding RNA HOXA-AS3 facilitates the malignancy in colorectal cancer by miR-4319/SPNS2 axis.
Jiang Y, Yu XY, Sun HX, Gu XY, Geng JS
Journal of physiology and biochemistry 2021 Nov;77(4):653-666
Journal of physiology and biochemistry 2021 Nov;77(4):653-666
Knockdown of ST6Gal-I expression in human hepatocellular carcinoma cells inhibits their exosome-mediated proliferation- and migration-promoting effects.
Wang L, Chen X, Wang L, Wang S, Li W, Liu Y, Zhang J
IUBMB life 2021 Nov;73(11):1378-1391
IUBMB life 2021 Nov;73(11):1378-1391
Activation of HIF1α Rescues the Hypoxic Response and Reverses Metabolic Dysfunction in the Diabetic Heart.
Sousa Fialho MDL, Purnama U, Dennis KMJH, Montes Aparicio CN, Castro-Guarda M, Massourides E, Tyler DJ, Carr CA, Heather LC
Diabetes 2021 Nov;70(11):2518-2531
Diabetes 2021 Nov;70(11):2518-2531
NCAPG, mediated by miR-378a-3p, regulates cell proliferation, cell cycle progression, and apoptosis of oral squamous cell carcinoma through the GSK-3β/β-catenin signaling.
Li J, Sun S, Li J, Zhao X, Li Z, Sha T, Cui Z
Neoplasma 2021 Nov;68(6):1201-1211
Neoplasma 2021 Nov;68(6):1201-1211
SARS-CoV-2 B.1.617.2 Delta variant replication and immune evasion.
Mlcochova P, Kemp SA, Dhar MS, Papa G, Meng B, Ferreira IATM, Datir R, Collier DA, Albecka A, Singh S, Pandey R, Brown J, Zhou J, Goonawardane N, Mishra S, Whittaker C, Mellan T, Marwal R, Datta M, Sengupta S, Ponnusamy K, Radhakrishnan VS, Abdullahi A, Charles O, Chattopadhyay P, Devi P, Caputo D, Peacock T, Wattal C, Goel N, Satwik A, Vaishya R, Agarwal M, Indian SARS-CoV-2 Genomics Consortium (INSACOG), Genotype to Phenotype Japan (G2P-Japan) Consortium, CITIID-NIHR BioResource COVID-19 Collaboration, Mavousian A, Lee JH, Bassi J, Silacci-Fegni C, Saliba C, Pinto D, Irie T, Yoshida I, Hamilton WL, Sato K, Bhatt S, Flaxman S, James LC, Corti D, Piccoli L, Barclay WS, Rakshit P, Agrawal A, Gupta RK
Nature 2021 Nov;599(7883):114-119
Nature 2021 Nov;599(7883):114-119
miR-221/222 suppression induced by activation of the cAMP/PKA/CREB1 pathway is required for cAMP-induced bidirectional differentiation of glioma cells.
Liu Q, Tian R, Yu P, Shu M
FEBS letters 2021 Nov;595(22):2829-2843
FEBS letters 2021 Nov;595(22):2829-2843
Effect of mifepristone and lithospermum combination regimen on medical abortion in early pregnancy rats.
Yu Q, Hu S, Hu S
The journal of obstetrics and gynaecology research 2021 Nov;47(11):3789-3796
The journal of obstetrics and gynaecology research 2021 Nov;47(11):3789-3796
Dihydroartemisinin triggers ferroptosis in primary liver cancer cells by promoting and unfolded protein response‑induced upregulation of CHAC1 expression.
Wang Z, Li M, Liu Y, Qiao Z, Bai T, Yang L, Liu B
Oncology reports 2021 Nov;46(5)
Oncology reports 2021 Nov;46(5)
Protein kinase G signaling pathway is involved in sympathetically maintained pain by modulating ATP-sensitive potassium channels.
Li H, Shang M, Liu L, Lin X, Hu J, Han Q, Xing J
Regional anesthesia and pain medicine 2021 Nov;46(11):1006-1011
Regional anesthesia and pain medicine 2021 Nov;46(11):1006-1011
MiR-214-3p plays a protective role in diabetic neuropathic rats by regulating Nav1.3 and TLR4.
Pang B, Qiao L, Wang S, Guo X, Xie Y, Han L
Cell biology international 2021 Nov;45(11):2294-2303
Cell biology international 2021 Nov;45(11):2294-2303
Silencing ACTG1 Expression Induces Prostate Cancer Epithelial Mesenchymal Transition Through MAPK/ERK Signaling Pathway.
Xiao L, Peng H, Yan M, Chen S
DNA and cell biology 2021 Nov;40(11):1445-1455
DNA and cell biology 2021 Nov;40(11):1445-1455
Selenium-modified calcium phosphate cement can accelerate bone regeneration of osteoporotic bone defect.
Li TL, Tao ZS, Wu XJ, Yang M, Xu HG
Journal of bone and mineral metabolism 2021 Nov;39(6):934-943
Journal of bone and mineral metabolism 2021 Nov;39(6):934-943
Novel WEE2 compound heterozygous mutations identified in patients with fertilization failure or poor fertilization.
Jin J, Tong X, Zhang YL, Yang W, Ma Y, Ren P, Zhou F, Zhang S
Journal of assisted reproduction and genetics 2021 Nov;38(11):2861-2869
Journal of assisted reproduction and genetics 2021 Nov;38(11):2861-2869
Rosamultin from Potentilla anserine L. exhibits nephroprotection and antioxidant activity by regulating the reactive oxygen species/C/EBP homologous protein signaling pathway.
He L, Liu N, Wang K, Zhang L, Li D, Wang Z, Xu G, Liu Y, Xu Q
Phytotherapy research : PTR 2021 Nov;35(11):6343-6358
Phytotherapy research : PTR 2021 Nov;35(11):6343-6358
Icariin attenuates renal fibrosis in chronic kidney disease by inhibiting interleukin-1β/transforming growth factor-β-mediated activation of renal fibroblasts.
Wang M, Wang L, Zhou Y, Feng X, Ye C, Wang C
Phytotherapy research : PTR 2021 Nov;35(11):6204-6215
Phytotherapy research : PTR 2021 Nov;35(11):6204-6215
Platycodon grandiflorum extract attenuates lipopolysaccharide-induced acute lung injury via TLR4/NF-κBp65 pathway in rats.
Si-Cong L, Chaoqin R, Ge L, Xu-Ting L, Jin-Liang L, Bin W, Min Z, Wei H, Liang C, Xue G
Pakistan journal of pharmaceutical sciences 2021 Nov;34(6):2213-2218
Pakistan journal of pharmaceutical sciences 2021 Nov;34(6):2213-2218
Vitamin D/VDR regulates peripheral energy homeostasis via central renin-angiotensin system.
Su H, Liu N, Zhang Y, Kong J
Journal of advanced research 2021 Nov;33:69-80
Journal of advanced research 2021 Nov;33:69-80
Cellular hnRNPAB interacts with avian influenza viral protein PB2 and inhibits virus replication potentially by restricting PB2 mRNA nuclear export and PB2 protein level.
Ye H, Bi Z, Fan W, Song S, Yan L
Virus research 2021 Nov;305:198573
Virus research 2021 Nov;305:198573
Environmental Pollutant Benzo[a]pyrene Upregulated Long Non-coding RNA HZ07 Inhibits Trophoblast Cell Migration by Inactivating PI3K/AKT/MMP2 Signaling Pathway in Recurrent Pregnancy Loss.
Ye Y, Jiang S, Du T, Ding M, Hou M, Mi C, Liang T, Zhong H, Xie J, Xu W, Zhang H, Zhao X
Reproductive sciences (Thousand Oaks, Calif.) 2021 Nov;28(11):3085-3093
Reproductive sciences (Thousand Oaks, Calif.) 2021 Nov;28(11):3085-3093
Mapping of pseudouridine residues on cellular and viral transcripts using a novel antibody-based technique.
Martinez Campos C, Tsai K, Courtney DG, Bogerd HP, Holley CL, Cullen BR
RNA (New York, N.Y.) 2021 Nov;27(11):1400-1411
RNA (New York, N.Y.) 2021 Nov;27(11):1400-1411
Japanese encephalitis virus restricts HMGB1 expression to maintain MAPK pathway activation for viral replication.
Xing J, Liang J, Liu S, Huang L, Hu P, Liu L, Liao M, Qi W
Veterinary microbiology 2021 Nov;262:109237
Veterinary microbiology 2021 Nov;262:109237
Drebrin, an actin-binding protein, is required for lens morphogenesis and growth.
Karnam S, Maddala R, Stiber JA, Rao PV
Developmental dynamics : an official publication of the American Association of Anatomists 2021 Nov;250(11):1600-1617
Developmental dynamics : an official publication of the American Association of Anatomists 2021 Nov;250(11):1600-1617
SC66 inhibits the proliferation and induces apoptosis of human bladder cancer cells by targeting the AKT/β-catenin pathway.
Chen W, Zhao S, Yu W, Rao T, Ruan Y, Zhu S, Xia Y, Song H, Cheng F
Journal of cellular and molecular medicine 2021 Nov;25(22):10684-10697
Journal of cellular and molecular medicine 2021 Nov;25(22):10684-10697
Casein Kinase II exacerbates rheumatoid arthritis via promoting Th1 and Th17 cell inflammatory responses.
Ye H, Fu D, Fang X, Xie Y, Zheng X, Fan W, Hu F, Li Z
Expert opinion on therapeutic targets 2021 Nov;25(11):1017-1024
Expert opinion on therapeutic targets 2021 Nov;25(11):1017-1024
miR‑486‑5p suppresses gastric cancer cell growth and migration through downregulation of fibroblast growth factor 9.
Wei W, Liu C, Yao R, Tan Q, Wang Q, Tian H
Molecular medicine reports 2021 Nov;24(5)
Molecular medicine reports 2021 Nov;24(5)
miR-106b-5p upregulation is associated with microglial activation and inflammation in the mouse hippocampus following status epilepticus.
Yu T, Fu H, Sun JJ, Ding DR, Wang H
Experimental brain research 2021 Nov;239(11):3315-3325
Experimental brain research 2021 Nov;239(11):3315-3325
In vivo assessment of molybdenum and cadmium co-induce nephrotoxicity via NLRP3/Caspase-1-mediated pyroptosis in ducks.
Zhang C, Wang X, Nie G, Wei Z, Pi S, Wang C, Yang F, Hu R, Xing C, Hu G
Journal of inorganic biochemistry 2021 Nov;224:111584
Journal of inorganic biochemistry 2021 Nov;224:111584
Inhibition of Dishevelled-2 suppresses the biological behavior of pancreatic cancer by downregulating Wnt/β-catenin signaling.
Hu W, Li M, Wu J, Chen H, Zhao T, Zhang C, Wang Z
Oncology letters 2021 Nov;22(5):769
Oncology letters 2021 Nov;22(5):769
An integrated RNA-Seq and network study reveals that valproate inhibited progesterone production in human granulosa cells.
Li S, Qi J, Sun Y, Gao X, Ma J, Zhao S
The Journal of steroid biochemistry and molecular biology 2021 Nov;214:105991
The Journal of steroid biochemistry and molecular biology 2021 Nov;214:105991
ML-SA1 and SN-2 inhibit endocytosed viruses through regulating TRPML channel expression and activity.
Xia Z, Ren Y, Li S, Xu J, Wu Y, Cao Z
Antiviral research 2021 Nov;195:105193
Antiviral research 2021 Nov;195:105193
Involvement of REV-ERBα dysregulation and ferroptosis in aristolochic acid I-induced renal injury.
Wang Y, Wang Z, Wu Z, Chen M, Dong D, Yu P, Lu D, Wu B
Biochemical pharmacology 2021 Nov;193:114807
Biochemical pharmacology 2021 Nov;193:114807
NEDD4 triggers FOXA1 ubiquitination and promotes colon cancer progression under microRNA-340-5p suppression and ATF1 upregulation.
Yue M, Yun Z, Li S, Yan G, Kang Z
RNA biology 2021 Nov;18(11):1981-1995
RNA biology 2021 Nov;18(11):1981-1995
Chitotriosidase attenuates brain inflammation via HDAC3/NF-κB pathway in D-galactose and aluminum-induced rat model with cognitive impairments.
Yu X, Yu W, Wu L, Yang W, Lü Y
Neuroscience research 2021 Nov;172:73-79
Neuroscience research 2021 Nov;172:73-79
B2M gene expression shapes the immune landscape of lung adenocarcinoma and determines the response to immunotherapy.
Zhao Y, Cao Y, Chen Y, Wu L, Hang H, Jiang C, Zhou X
Immunology 2021 Nov;164(3):507-523
Immunology 2021 Nov;164(3):507-523
Multifunctional MnO(2)-based nanoplatform-induced ferroptosis and apoptosis for synergetic chemoradiotherapy.
Li X, Wang Q, Yu S, Zhang M, Liu X, Deng G, Liu Y, Wu S
Nanomedicine (London, England) 2021 Nov;16(26):2343-2361
Nanomedicine (London, England) 2021 Nov;16(26):2343-2361
Fragile X mental retardation protein-regulated proinflammatory cytokine expression in the spinal cord contributes to the pathogenesis of inflammatory pain induced by complete Freund's adjuvant.
Yang Y, Zhao J, Li Y, Li X, Chen X, Feng Z
Journal of neurochemistry 2021 Nov;159(3):512-524
Journal of neurochemistry 2021 Nov;159(3):512-524
Prenatal EGCG exposure-induced heart mass reduction in adult male mice and underlying mechanisms.
Zhang S, Ou K, Huang J, Fang L, Wang C, Wang Q
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2021 Nov;157:112588
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2021 Nov;157:112588
1,3-dichloro-2-propanol induced hepatic lipid accumulation by inhibiting autophagy via AKT/mTOR/FOXO1 pathway in mice.
Fan Y, Lu J, Liu J, Zhang R, Yu Z, Guan S
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2021 Nov;157:112578
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2021 Nov;157:112578
Perfluorooctane sulfonate induces autophagy-dependent lysosomal membrane permeabilization by weakened interaction between tyrosinated alpha-tubulin and spinster 1.
Dong Z, Qiu T, Zhang J, Sha S, Han X, Kang J, Shi X, Sun X, Jiang L, Yang G, Yao X, Ma Y
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2021 Nov;157:112540
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2021 Nov;157:112540
Varied thyroid disrupting effects of perfluorooctanoic acid (PFOA) and its novel alternatives hexafluoropropylene-oxide-dimer-acid (GenX) and ammonium 4,8-dioxa-3H-perfluorononanoate (ADONA) in vitro.
Zhang S, Chen K, Li W, Chai Y, Zhu J, Chu B, Li N, Yan J, Zhang S, Yang Y
Environment international 2021 Nov;156:106745
Environment international 2021 Nov;156:106745
αCaMKII in the lateral amygdala mediates PTSD-Like behaviors and NMDAR-Dependent LTD.
An S, Wang J, Zhang X, Duan Y, Xu Y, Lv J, Wang D, Zhang H, Richter-Levin G, Klavir O, Yu B, Cao X
Neurobiology of stress 2021 Nov;15:100359
Neurobiology of stress 2021 Nov;15:100359
Liraglutide ameliorates diabetes-associated cognitive dysfunction via rescuing autophagic flux.
Zhang M, Yan W, Yu Y, Cheng J, Yi X, Guo T, Liu N, Shang J, Wang Z, Hu H, Chen L
Journal of pharmacological sciences 2021 Nov;147(3):234-244
Journal of pharmacological sciences 2021 Nov;147(3):234-244
Osteopontin improves sensitivity to tyrosine kinase inhibitor in lung adenocarcinoma in vitro by promoting epidermal growth factor receptor phosphorylation.
Wang YJ, Wang QW, Yu DH, Song CK, Guo ZX, Liu XP, Chen C, Yao J, Wang AF, Hu WD
Journal of cancer research and clinical oncology 2021 Nov;147(11):3245-3254
Journal of cancer research and clinical oncology 2021 Nov;147(11):3245-3254
Selenium-enriched Bifidobacterium longum DD98 attenuates irinotecan-induced intestinal and hepatic toxicity in vitro and in vivo.
Zhu H, Lu C, Gao F, Qian Z, Yin Y, Kan S, Chen D
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Nov;143:112192
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Nov;143:112192
Platycodon grandiflorus polysaccharides inhibit Pseudorabies virus replication via downregulating virus-induced autophagy.
Xing Y, Wang L, Xu G, Guo S, Zhang M, Cheng G, Liu Y, Liu J
Research in veterinary science 2021 Nov;140:18-25
Research in veterinary science 2021 Nov;140:18-25
Deficiency in WDFY4 reduces the number of CD8(+) T cells via reactive oxygen species-induced apoptosis.
Li Y, Li J, Yuan Q, Bian X, Long F, Duan R, Gao F, Gao S, Wei S, Wang A, Liu A, Li X, Sun W, Liu Q
Molecular immunology 2021 Nov;139:131-138
Molecular immunology 2021 Nov;139:131-138
RIP1-dependent linear and nonlinear recruitments of caspase-8 and RIP3 respectively to necrosome specify distinct cell death outcomes.
Li X, Zhong CQ, Wu R, Xu X, Yang ZH, Cai S, Wu X, Chen X, Yin Z, He Q, Li D, Xu F, Yan Y, Qi H, Xie C, Shuai J, Han J
Protein & cell 2021 Nov;12(11):858-876
Protein & cell 2021 Nov;12(11):858-876
Synthesis and evaluation of 3-(phenylethynyl)-1,1'-biphenyl-2-carboxylate derivatives as new HIF-1 inhibitors.
Wang S, Wang X, Shao Y, Shao K, Wang Y, Guo X, Dong H, Zhao W, Li Y, Li G
Bioorganic chemistry 2021 Nov;116:105298
Bioorganic chemistry 2021 Nov;116:105298
DOC-2/DAB2 interactive protein destabilizes c-Myc to impair the growth and self-renewal of colon tumor-repopulating cells.
Li H, Zhou Y, Wang M, Wang H, Zhang Y, Peng R, Zhang R, Zhang M, Zhang M, Qiu P, Liu L, Zhao Q, Liu J
Cancer science 2021 Nov;112(11):4593-4603
Cancer science 2021 Nov;112(11):4593-4603
HIF2α promotes tumour growth in clear cell renal cell carcinoma by increasing the expression of NUDT1 to reduce oxidative stress.
Shi J, Xiong Z, Wang K, Yuan C, Huang Y, Xiao W, Meng X, Chen Z, Lv Q, Miao D, Liang H, Xu T, Xie K, Yang H, Zhang X
Clinical and translational medicine 2021 Nov;11(11):e592
Clinical and translational medicine 2021 Nov;11(11):e592
Protocatechuic aldehyde protects cardiomycoytes against ischemic injury via regulation of nuclear pyruvate kinase M2.
Wu X, Liu L, Zheng Q, Hao H, Ye H, Li P, Yang H
Acta pharmaceutica Sinica. B 2021 Nov;11(11):3553-3566
Acta pharmaceutica Sinica. B 2021 Nov;11(11):3553-3566
Ceruloplasmin overexpression is associated with oncogenic pathways and poorer survival rates in clear-cell renal cell carcinoma.
Zhang Y, Chen Z, Chen JG, Chen XF, Gu DH, Liu ZM, Gao YD, Zheng B
FEBS open bio 2021 Nov;11(11):2988-3004
FEBS open bio 2021 Nov;11(11):2988-3004
LINC00370 modulates miR-222-3p-RGS4 axis to protect against osteoporosis progression.
Li L, Zheng B, Zhang F, Luo X, Li F, Xu T, Zhao H, Shi G, Guo Y, Shi J, Sun J
Archives of gerontology and geriatrics 2021 Nov-Dec;97:104505
Archives of gerontology and geriatrics 2021 Nov-Dec;97:104505
CD38 deficiency up-regulated IL-1β and MCP-1 through TLR4/ERK/NF-κB pathway in sepsis pulmonary injury.
Du Y, Zhang H, Guo Y, Song K, Zeng L, Chen Y, Xie Z, Li R
Microbes and infection 2021 Nov-Dec;23(9-10):104845
Microbes and infection 2021 Nov-Dec;23(9-10):104845
Direct Activation of Endothelial Cells by SARS-CoV-2 Nucleocapsid Protein Is Blocked by Simvastatin.
Qian Y, Lei T, Patel PS, Lee CH, Monaghan-Nichols P, Xin HB, Qiu J, Fu M
Journal of virology 2021 Nov 9;95(23):e0139621
Journal of virology 2021 Nov 9;95(23):e0139621
Discovery of Phenolic Glycoside from Hyssopus cuspidatus Attenuates LPS-Induced Inflammatory Responses by Inhibition of iNOS and COX-2 Expression through Suppression of NF-κB Activation.
Liu X, Su J, Wang G, Zheng L, Wang G, Sun Y, Bao Y, Wang S, Huang Y
International journal of molecular sciences 2021 Nov 9;22(22)
International journal of molecular sciences 2021 Nov 9;22(22)
HSD17B6 downregulation predicts poor prognosis and drives tumor progression via activating Akt signaling pathway in lung adenocarcinoma.
Tian T, Hong F, Wang Z, Hu J, Chen N, Lv L, Yi Q
Cell death discovery 2021 Nov 8;7(1):341
Cell death discovery 2021 Nov 8;7(1):341
High throughput sequencing of whole transcriptome and construct of ceRNA regulatory network in RD cells infected with enterovirus D68.
Si J, Tang X, Xu L, Fu H, Li H, He Y, Bao J, Tang J, Li A, Lu N, Yang C
Virology journal 2021 Nov 7;18(1):216
Virology journal 2021 Nov 7;18(1):216
LPS-induced macrophage HMGB1-loaded extracellular vesicles trigger hepatocyte pyroptosis by activating the NLRP3 inflammasome.
Wang G, Jin S, Huang W, Li Y, Wang J, Ling X, Huang Y, Hu Y, Li C, Meng Y, Li X
Cell death discovery 2021 Nov 6;7(1):337
Cell death discovery 2021 Nov 6;7(1):337
Total glycosides from Eucommia ulmoides seed promoted osteogenic differentiation of adipose-derived mesenchymal stem cells and bone formation in ovariectomized rats through regulating Notch signaling pathway.
Zhou YH, Xie Q
Journal of orthopaedic surgery and research 2021 Nov 6;16(1):660
Journal of orthopaedic surgery and research 2021 Nov 6;16(1):660
Erythromycin reduces nasal inflammation by inhibiting immunoglobulin production, attenuating mucus secretion, and modulating cytokine expression.
Yen TT, Jiang RS, Chang CY, Wu CY, Liang KL
Scientific reports 2021 Nov 5;11(1):21737
Scientific reports 2021 Nov 5;11(1):21737
Increased expression of TAZ and associated upregulation of PD-L1 in cervical cancer.
Han Y, Liu D, Li L
Cancer cell international 2021 Nov 4;21(1):592
Cancer cell international 2021 Nov 4;21(1):592
GSK-3β manipulates ferroptosis sensitivity by dominating iron homeostasis.
Wang L, Ouyang S, Li B, Wu H, Wang F
Cell death discovery 2021 Nov 3;7(1):334
Cell death discovery 2021 Nov 3;7(1):334
Long non-coding RNA SNHG1 promotes fibroblast-to-myofibroblast transition during the development of pulmonary fibrosis induced by silica particles exposure.
Wu Q, Jiao B, Gui W, Zhang Q, Wang F, Han L
Ecotoxicology and environmental safety 2021 Nov 3;228:112938
Ecotoxicology and environmental safety 2021 Nov 3;228:112938
Taxifolin retards the D-galactose-induced aging process through inhibiting Nrf2-mediated oxidative stress and regulating the gut microbiota in mice.
Liu XL, Zhao YC, Zhu HY, Wu M, Zheng YN, Yang M, Cheng ZQ, Ding CB, Liu WC
Food & function 2021 Nov 29;12(23):12142-12158
Food & function 2021 Nov 29;12(23):12142-12158
Cardamonin inhibits osteogenic differentiation of human valve interstitial cells and ameliorates aortic valve calcification via interfering in the NF-κB/NLRP3 inflammasome pathway.
Wang C, Xia Y, Qu L, Liu Y, Liu X, Xu K
Food & function 2021 Nov 29;12(23):11808-11818
Food & function 2021 Nov 29;12(23):11808-11818
MICU3 regulates mitochondrial Ca(2+)-dependent antioxidant response in skeletal muscle aging.
Yang YF, Yang W, Liao ZY, Wu YX, Fan Z, Guo A, Yu J, Chen QN, Wu JH, Zhou J, Xiao Q
Cell death & disease 2021 Nov 29;12(12):1115
Cell death & disease 2021 Nov 29;12(12):1115
LAGE3 promoted cell proliferation, migration, and invasion and inhibited cell apoptosis of hepatocellular carcinoma by facilitating the JNK and ERK signaling pathway.
Xing Y, Liu Y, Qi Z, Liu Z, Wang X, Zhang H
Cellular & molecular biology letters 2021 Nov 27;26(1):49
Cellular & molecular biology letters 2021 Nov 27;26(1):49
NEDD4L-induced ubiquitination mediating UBE2T degradation inhibits progression of lung adenocarcinoma via PI3K-AKT signaling.
Chen Y, Hong H, Wang Q, Li J, Zhang W, Chen T, Li P
Cancer cell international 2021 Nov 27;21(1):631
Cancer cell international 2021 Nov 27;21(1):631
Downregulation of miR-29c promotes muscle wasting by modulating the activity of leukemia inhibitory factor in lung cancer cachexia.
Xie K, Xiong H, Xiao W, Xiong Z, Hu W, Ye J, Xu N, Shi J, Yuan C, Chen Z, Miao D, Zhang X, Yang H
Cancer cell international 2021 Nov 27;21(1):627
Cancer cell international 2021 Nov 27;21(1):627
Bone morphogenetic protein 9 enhances osteogenic and angiogenic responses of human amniotic mesenchymal stem cells cocultured with umbilical vein endothelial cells through the PI3K/AKT/m-TOR signaling pathway.
Liu Z, Li Y, Yang J, Huang J, Luo C, Zhang J, Yan W, Ao Y
Aging 2021 Nov 27;13(22):24829-24849
Aging 2021 Nov 27;13(22):24829-24849
Sesquiterpene Lactones from Sigesbeckia glabrescens Possessing Potent Anti-inflammatory Activity by Directly Binding to IKKα/β.
Gao X, Shen X, Zheng Y, Yang L, Zhang X, Hu G, Jia J, Wang A
Journal of natural products 2021 Nov 26;84(11):2808-2821
Journal of natural products 2021 Nov 26;84(11):2808-2821
Oxidative stress transforms 3CLpro into an insoluble and more active form to promote SARS-CoV-2 replication.
Du L, Xie Y, Zheng K, Wang N, Gao M, Yu T, Cao L, Shao Q, Zou Y, Xia W, Fang Q, Zhao B, Guo D, Peng X, Pan JA
Redox biology 2021 Nov 26;48:102199
Redox biology 2021 Nov 26;48:102199
Reciprocal regulation of LOXL2 and HIF1α drives the Warburg effect to support pancreatic cancer aggressiveness.
Li R, Li H, Zhu L, Zhang X, Liu D, Li Q, Ni B, Hu L, Zhang Z, Zhang Y, Wang X, Jiang SH
Cell death & disease 2021 Nov 26;12(12):1106
Cell death & disease 2021 Nov 26;12(12):1106
Structure-Based Discovery of Potent CARM1 Inhibitors for Solid Tumor and Cancer Immunology Therapy.
Zhang Z, Guo Z, Xu X, Cao D, Yang H, Li Y, Shi Q, Du Z, Guo X, Wang X, Chen D, Zhang Y, Chen L, Zhou K, Li J, Geng M, Huang X, Xiong B
Journal of medicinal chemistry 2021 Nov 25;64(22):16650-16674
Journal of medicinal chemistry 2021 Nov 25;64(22):16650-16674
The structural basis for the phospholipid remodeling by lysophosphatidylcholine acyltransferase 3.
Zhang Q, Yao D, Rao B, Jian L, Chen Y, Hu K, Xia Y, Li S, Shen Y, Qin A, Zhao J, Zhou L, Lei M, Jiang XC, Cao Y
Nature communications 2021 Nov 25;12(1):6869
Nature communications 2021 Nov 25;12(1):6869
Urinary peptidomics reveals proteases involved in idiopathic membranous nephropathy.
Lin B, Liu J, Zhang Y, Wu Y, Chen S, Bai Y, Liu Q, Qin X
BMC genomics 2021 Nov 24;22(1):852
BMC genomics 2021 Nov 24;22(1):852
miR-30b-5p inhibits proliferation, invasion, and migration of papillary thyroid cancer by targeting GALNT7 via the EGFR/PI3K/AKT pathway.
Wang Y, Wang C, Fu Z, Zhang S, Chen J
Cancer cell international 2021 Nov 24;21(1):618
Cancer cell international 2021 Nov 24;21(1):618
Extracellular vesicles derived from hypoxia-preconditioned olfactory mucosa mesenchymal stem cells enhance angiogenesis via miR-612.
Ge L, Xun C, Li W, Jin S, Liu Z, Zhuo Y, Duan D, Hu Z, Chen P, Lu M
Journal of nanobiotechnology 2021 Nov 21;19(1):380
Journal of nanobiotechnology 2021 Nov 21;19(1):380
Cadmium attenuates testosterone synthesis by promoting ferroptosis and blocking autophagosome-lysosome fusion.
Zeng L, Zhou J, Wang X, Zhang Y, Wang M, Su P
Free radical biology & medicine 2021 Nov 20;176:176-188
Free radical biology & medicine 2021 Nov 20;176:176-188
IRF3-binding lncRNA-ISIR strengthens interferon production in viral infection and autoinflammation.
Xu J, Wang P, Li Z, Li Z, Han D, Wen M, Zhao Q, Zhang L, Ma Y, Liu W, Jiang M, Zhang X, Cao X
Cell reports 2021 Nov 2;37(5):109926
Cell reports 2021 Nov 2;37(5):109926
Blood-Based Epigenetic Markers of FKBP5 Gene Methylation in Patients With Dilated Cardiomyopathy.
Wada K, Misaka T, Yokokawa T, Kimishima Y, Kaneshiro T, Oikawa M, Yoshihisa A, Takeishi Y
Journal of the American Heart Association 2021 Nov 2;10(21):e021101
Journal of the American Heart Association 2021 Nov 2;10(21):e021101
The Y14-p53 regulatory circuit in megakaryocyte differentiation and thrombocytopenia.
Su CH, Liao WJ, Ke WC, Yang RB, Tarn WY
iScience 2021 Nov 19;24(11):103368
iScience 2021 Nov 19;24(11):103368
Capping protein regulates endosomal trafficking by controlling F-actin density around endocytic vesicles and recruiting RAB5 effectors.
Wang D, Ye Z, Wei W, Yu J, Huang L, Zhang H, Yue J
eLife 2021 Nov 19;10
eLife 2021 Nov 19;10
TBHQ attenuates ferroptosis against 5-fluorouracil-induced intestinal epithelial cell injury and intestinal mucositis via activation of Nrf2.
Deng S, Wu D, Li L, Li J, Xu Y
Cellular & molecular biology letters 2021 Nov 18;26(1):48
Cellular & molecular biology letters 2021 Nov 18;26(1):48
Indole-3-Propionic Acid, a Functional Metabolite of Clostridium sporogenes, Promotes Muscle Tissue Development and Reduces Muscle Cell Inflammation.
Du L, Qi R, Wang J, Liu Z, Wu Z
International journal of molecular sciences 2021 Nov 18;22(22)
International journal of molecular sciences 2021 Nov 18;22(22)
Inhibition of DTYMK significantly restrains the growth of HCC and increases sensitivity to oxaliplatin.
Sun F, Liu Y, Gong T, Pan Q, Xiang T, Zhao J, Tang Y, Chen H, Han Y, Song M, Huang Y, Li H, Chen Y, Yang C, Yang J, Wang Q, Li Y, He J, Weng D, Peng R, Xia J
Cell death & disease 2021 Nov 18;12(12):1093
Cell death & disease 2021 Nov 18;12(12):1093
Identification of proximal SUMO-dependent interactors using SUMO-ID.
Barroso-Gomila O, Trulsson F, Muratore V, Canosa I, Merino-Cacho L, Cortazar AR, Pérez C, Azkargorta M, Iloro I, Carracedo A, Aransay AM, Elortza F, Mayor U, Vertegaal ACO, Barrio R, Sutherland JD
Nature communications 2021 Nov 18;12(1):6671
Nature communications 2021 Nov 18;12(1):6671
Shikonin Induced Program Cell Death through Generation of Reactive Oxygen Species in Renal Cancer Cells.
Tsai MF, Chen SM, Ong AZ, Chung YH, Chen PN, Hsieh YH, Kang YT, Hsu LS
Antioxidants (Basel, Switzerland) 2021 Nov 18;10(11)
Antioxidants (Basel, Switzerland) 2021 Nov 18;10(11)
Fluoride Stimulates Anxiety- and Depression-like Behaviors Associated with SIK2-CRTC1 Signaling Dysfunction.
Zhou G, Hu Y, Wang A, Guo M, Du Y, Gong Y, Ding L, Feng Z, Hou X, Xu K, Yu F, Li Z, Ba Y
Journal of agricultural and food chemistry 2021 Nov 17;69(45):13618-13627
Journal of agricultural and food chemistry 2021 Nov 17;69(45):13618-13627
Dendrobium officinale Polysaccharide Alleviates Intestinal Inflammation by Promoting Small Extracellular Vesicle Packaging of miR-433-3p.
Liu H, Liang J, Zhong Y, Xiao G, Efferth T, Georgiev MI, Vargas-De-La-Cruz C, Bajpai VK, Caprioli G, Liu J, Lin J, Wu H, Peng L, Li Y, Ma L, Xiao J, Wang Q
Journal of agricultural and food chemistry 2021 Nov 17;69(45):13510-13523
Journal of agricultural and food chemistry 2021 Nov 17;69(45):13510-13523
Knockdown of circFOXO3 ameliorates cigarette smoke-induced lung injury in mice.
Zhou L, Wu B, Yang J, Wang B, Pan J, Xu D, Du C
Respiratory research 2021 Nov 17;22(1):294
Respiratory research 2021 Nov 17;22(1):294
Knockout of mafba Causes Inner-Ear Developmental Defects in Zebrafish via the Impairment of Proliferation and Differentiation of Ionocyte Progenitor Cells.
Chen X, Huang Y, Gao P, Lv Y, Jia D, Sun K, Han Y, Hu H, Tang Z, Ren X, Liu M
Biomedicines 2021 Nov 16;9(11)
Biomedicines 2021 Nov 16;9(11)
Inhibition of DCLK1 with DCLK1-IN-1 Suppresses Renal Cell Carcinoma Invasion and Stemness and Promotes Cytotoxic T-Cell-Mediated Anti-Tumor Immunity.
Ding L, Yang Y, Ge Y, Lu Q, Yan Z, Chen X, Du J, Hafizi S, Xu X, Yao J, Liu J, Cao Z, Weygant N
Cancers 2021 Nov 16;13(22)
Cancers 2021 Nov 16;13(22)
Remodelling of gut microbiota by Berberine attenuates trimethylamine N-oxide-induced platelet hyperreaction and thrombus formation.
Xie Z, Liu X, Huang X, Liu Q, Yang M, Huang D, Zhao P, Tian J, Wang X, Hou J
European journal of pharmacology 2021 Nov 15;911:174526
European journal of pharmacology 2021 Nov 15;911:174526
STOML2 interacts with PHB through activating MAPK signaling pathway to promote colorectal Cancer proliferation.
Ma W, Chen Y, Xiong W, Li W, Xu Z, Wang Y, Wei Z, Mou T, Wu Z, Cheng M, Zou Y, Zhu Y, Zhou W, Liu F, Geng Y
Journal of experimental & clinical cancer research : CR 2021 Nov 15;40(1):359
Journal of experimental & clinical cancer research : CR 2021 Nov 15;40(1):359
Babao Dan is a robust anti-tumor agent via inhibiting wnt/β-catenin activation and cancer cell stemness.
Xie X, Chen J, Wo D, Ma E, Ning Y, Peng J, Zhu W, Ren DN
Journal of ethnopharmacology 2021 Nov 15;280:114449
Journal of ethnopharmacology 2021 Nov 15;280:114449
Single-Cell Analyses Reveal Mechanisms of Cancer Stem Cell Maintenance and Epithelial-Mesenchymal Transition in Recurrent Bladder Cancer.
Wang H, Mei Y, Luo C, Huang Q, Wang Z, Lu GM, Qin L, Sun Z, Huang CW, Yang ZW, Chen J, Yin W, Qian CN, Zeng J, Chen L, Leng Q, Guo Y, Jia G
Clinical cancer research : an official journal of the American Association for Cancer Research 2021 Nov 15;27(22):6265-6278
Clinical cancer research : an official journal of the American Association for Cancer Research 2021 Nov 15;27(22):6265-6278
(-)-Epigallocatechin-3-gallate mitigates cyclophosphamide-induced intestinal injury by modulating the tight junctions, inflammation and dysbiosis in mice.
Wei R, Liu X, Wang Y, Dong J, Wu F, Mackenzie GG, Su Z
Food & function 2021 Nov 15;12(22):11671-11685
Food & function 2021 Nov 15;12(22):11671-11685
SARS-CoV-2 inhibits induction of the MHC class I pathway by targeting the STAT1-IRF1-NLRC5 axis.
Yoo JS, Sasaki M, Cho SX, Kasuga Y, Zhu B, Ouda R, Orba Y, de Figueiredo P, Sawa H, Kobayashi KS
Nature communications 2021 Nov 15;12(1):6602
Nature communications 2021 Nov 15;12(1):6602
Inhibition of METTL3/m6A/miR126 promotes the migration and invasion of endometrial stromal cells in endometriosis†.
Li X, Xiong W, Long X, Dai X, Peng Y, Xu Y, Zhang Z, Zhang L, Liu Y
Biology of reproduction 2021 Nov 15;105(5):1221-1233
Biology of reproduction 2021 Nov 15;105(5):1221-1233
PRMT1-mediated EZH2 methylation promotes breast cancer cell proliferation and tumorigenesis.
Li Z, Wang D, Chen X, Wang W, Wang P, Hou P, Li M, Chu S, Qiao S, Zheng J, Bai J
Cell death & disease 2021 Nov 13;12(11):1080
Cell death & disease 2021 Nov 13;12(11):1080
TM9SF4 is a novel regulator in lineage commitment of bone marrow mesenchymal stem cells to either osteoblasts or adipocytes.
Yu L, Xie M, Zhang F, Wan C, Yao X
Stem cell research & therapy 2021 Nov 13;12(1):573
Stem cell research & therapy 2021 Nov 13;12(1):573
LRG1 destabilizes tumor vessels and restricts immunotherapeutic potency.
O'Connor MN, Kallenberg DM, Camilli C, Pilotti C, Dritsoula A, Jackstadt R, Bowers CE, Watson HA, Alatsatianos M, Ohme J, Dowsett L, George J, Blackburn JWD, Wang X, Singhal M, Augustin HG, Ager A, Sansom OJ, Moss SE, Greenwood J
Med (New York, N.Y.) 2021 Nov 12;2(11):1231-1252.e10
Med (New York, N.Y.) 2021 Nov 12;2(11):1231-1252.e10
Discovery of a Dual Tubulin and Poly(ADP-Ribose) Polymerase-1 Inhibitor by Structure-Based Pharmacophore Modeling, Virtual Screening, Molecular Docking, and Biological Evaluation.
Zheng L, Ren R, Sun X, Zou Y, Shi Y, Di B, Niu MM
Journal of medicinal chemistry 2021 Nov 11;64(21):15702-15715
Journal of medicinal chemistry 2021 Nov 11;64(21):15702-15715
The Large GTPase, GBP-2, Regulates Rho Family GTPases to Inhibit Migration and Invadosome Formation in Breast Cancer Cells.
Nyabuto GO, Wilson JP, Heilman SA, Kalb RC, Kopacz JP, Abnave AV, Vestal DJ
Cancers 2021 Nov 11;13(22)
Cancers 2021 Nov 11;13(22)
Deletion of miR-15a inhibited glioma development via targeting Smad7 and inhibiting EMT pathway.
Guo Y, Gao X, An S, Li X, Pan L, Liu H, Liu J, Gao J, Zhao Z, Li G, Han Y, Li Y, Ji Z
Aging 2021 Nov 11;13(21):24339-24348
Aging 2021 Nov 11;13(21):24339-24348
Resveratrol induces proliferation in preosteoblast cell MC3T3-E1 via GATA-1 activating autophagy.
Liu X, Tao J, Yao Y, Yang P, Wang J, Yu M, Hou J, Zhang Y, Gui LI
Acta biochimica et biophysica Sinica 2021 Nov 10;53(11):1495-1504
Acta biochimica et biophysica Sinica 2021 Nov 10;53(11):1495-1504
Mof acetyltransferase inhibition ameliorates glucose intolerance and islet dysfunction of type 2 diabetes via targeting pancreatic α-cells.
Guo X, Cui C, Song J, He Q, Zang N, Hu H, Wang X, Li D, Wang C, Hou X, Li X, Liang K, Yan F, Chen L
Molecular and cellular endocrinology 2021 Nov 1;537:111425
Molecular and cellular endocrinology 2021 Nov 1;537:111425
Isorhapontigenin (ISO) inhibits EMT through FOXO3A/METTL14/VIMENTIN pathway in bladder cancer cells.
Zhang N, Hua X, Tu H, Li J, Zhang Z, Max C
Cancer letters 2021 Nov 1;520:400-408
Cancer letters 2021 Nov 1;520:400-408
Sodium cantharidate induces Apoptosis in breast cancer cells by regulating energy metabolism via the protein phosphatase 5-p53 axis.
Pang JL, Huang FH, Zhang YH, Wu Y, Ge XM, Li S, Li X
Toxicology and applied pharmacology 2021 Nov 1;430:115726
Toxicology and applied pharmacology 2021 Nov 1;430:115726
Neurotoxicity of a pyrethroid pesticide deltamethrin is associated with the imbalance in proteolytic systems caused by mitophagy activation and proteasome inhibition.
Hirano T, Suzuki N, Ikenaka Y, Hoshi N, Tabuchi Y
Toxicology and applied pharmacology 2021 Nov 1;430:115723
Toxicology and applied pharmacology 2021 Nov 1;430:115723
Comparative analysis of the MyTH4-FERM myosins reveals insights into the determinants of actin track selection in polarized epithelia.
Matoo S, Graves MJ, Acharya P, Choi MS, Storad ZA, Idris RAES, Pickles BK, Arvay TO, Shinder PE, Gerts A, Papish JP, Crawley SW
Molecular biology of the cell 2021 Nov 1;32(21):ar30
Molecular biology of the cell 2021 Nov 1;32(21):ar30
Muse Cells Have Higher Stress Tolerance than Adipose Stem Cells due to the Overexpression of the CCNA2 Gene.
Wang P, Wang S, Ji F, Zhang R
Stem cells and development 2021 Nov 1;30(21):1056-1069
Stem cells and development 2021 Nov 1;30(21):1056-1069
A novel mutation in NF1 gene of patient with Neurofibromatosis type 1: A case report and functional study.
Zhang T, Jia C, Dong Z, Li C, Lu W
Molecular genetics & genomic medicine 2021 May;9(5):e1643
Molecular genetics & genomic medicine 2021 May;9(5):e1643
Trojan Horse Delivery of 4,4'-Dimethoxychalcone for Parkinsonian Neuroprotection.
Zhang W, Chen H, Ding L, Gong J, Zhang M, Guo W, Xu P, Li S, Zhang Y
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2021 May;8(9):2004555
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2021 May;8(9):2004555
Aldehyde Dehydrogenase 2 Mediates Alcohol-Induced Colorectal Cancer Immune Escape through Stabilizing PD-L1 Expression.
Zhang H, Xia Y, Wang F, Luo M, Yang K, Liang S, An S, Wu S, Yang C, Chen D, Xu M, Cai M, To KKW, Fu L
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2021 May;8(10):2003404
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2021 May;8(10):2003404
Overproduced CPSF4 Promotes Cell Proliferation and Invasion via PI3K-AKT Signaling Pathway in Oral Squamous Cell Carcinoma.
Zhang M, Lin H, Ge X, Xu Y
Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons 2021 May;79(5):1177.e1-1177.e14
Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons 2021 May;79(5):1177.e1-1177.e14
Elevated type I interferon responses potentiate metabolic dysfunction, inflammation, and accelerated aging in mtDNA mutator mice.
Lei Y, Guerra Martinez C, Torres-Odio S, Bell SL, Birdwell CE, Bryant JD, Tong CW, Watson RO, West LC, West AP
Science advances 2021 May;7(22)
Science advances 2021 May;7(22)
Centrosomal protein FOR20 knockout mice display embryonic lethality and left-right patterning defects.
Xu Z, Liu M, Gao C, Kuang W, Chen X, Liu F, Ge B, Yan X, Zhou T, Xie S
FEBS letters 2021 May;595(10):1462-1472
FEBS letters 2021 May;595(10):1462-1472
The Long Noncoding RNA Hepatocyte Nuclear Factor 4α Antisense RNA 1 Negatively Regulates Cytochrome P450 Enzymes in Huh7 Cells via Histone Modifications.
Wang P, Chen S, Wang Y, Wang X, Yan L, Yang K, Zhong XB, Han S, Zhang L
Drug metabolism and disposition: the biological fate of chemicals 2021 May;49(5):361-368
Drug metabolism and disposition: the biological fate of chemicals 2021 May;49(5):361-368
MiR-195-5p inhibits proliferation and invasion of nerve cells in Hirschsprung disease by targeting GFRA4.
Wang G, Wang H, Zhang L, Guo F, Wu X, Liu Y
Molecular and cellular biochemistry 2021 May;476(5):2061-2073
Molecular and cellular biochemistry 2021 May;476(5):2061-2073
TGIF1 plays a carcinogenic role in esophageal squamous cell carcinoma through the Wnt/β‑catenin and Akt/mTOR signaling pathways.
Kong L, Yu Y, Guan H, Jiang L, Sun F, Li X, Huang W, Li B
International journal of molecular medicine 2021 May;47(5)
International journal of molecular medicine 2021 May;47(5)
LINC01816 promotes the migration, invasion and epithelial‑mesenchymal transition of thyroid carcinoma cells by sponging miR‑34c‑5p and regulating CRABP2 expression levels.
Zhao H, Zhu X, Luo Y, Liu S, Wu W, Zhang L, Zhu J
Oncology reports 2021 May;45(5)
Oncology reports 2021 May;45(5)
Methylation gene KCNC1 is associated with overall survival in patients with seminoma.
Chen S, Xiao L, Peng H, Wang Z, Xie J
Oncology reports 2021 May;45(5)
Oncology reports 2021 May;45(5)
Novel gene-encoded intermolecular FRET sensor for tracking glycosylation of CD147 in living cells.
Lu H, Zhu L, Li W, Hu S, Ge Y, Liu D
Analytical and bioanalytical chemistry 2021 May;413(12):3193-3199
Analytical and bioanalytical chemistry 2021 May;413(12):3193-3199
Relevance of CYP3A5 Expression on the Clinical Outcome of Patients With Renal Cell Carcinoma.
Matsumoto J, Kotera Y, Watari S, Takeuchi K, Ueki H, Koyama T, Wada K, Fujiyoshi M, Nasu Y, Ariyoshi N
Anticancer research 2021 May;41(5):2511-2521
Anticancer research 2021 May;41(5):2511-2521
Acetaldehyde Dehydrogenase 2 regulates HMG-CoA reductase stability and cholesterol synthesis in the liver.
Zhong S, Li L, Liang N, Zhang L, Xu X, Chen S, Yin H
Redox biology 2021 May;41:101919
Redox biology 2021 May;41:101919
Long non-coding RNA SMASR inhibits the EMT by negatively regulating TGF-β/Smad signaling pathway in lung cancer.
Xu L, Liu W, Li T, Hu Y, Wang Y, Huang L, Wang Y, Shao S, Liu X, Zhan Q
Oncogene 2021 May;40(20):3578-3592
Oncogene 2021 May;40(20):3578-3592
Antiangiogenic effect of arsenic trioxide in HUVECs by FoxO3a-regulated autophagy.
Sun Z, Cao Y, Xing Y, Wu M, Shao X, Huang Q, Bai L, Wang L, Zhao Y, Wu Y
Journal of biochemical and molecular toxicology 2021 May;35(5):e22728
Journal of biochemical and molecular toxicology 2021 May;35(5):e22728
Glucose-dependent insulinotropic polypeptide modifies adipose plasticity and promotes beige adipogenesis of human omental adipose-derived stem cells.
Chen X, He X, Guo Y, Liu L, Li H, Tan J, Feng W, Guan H, Cao X, Xiao H, Li Y
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 May;35(5):e21534
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 May;35(5):e21534
L-leucine promotes axonal outgrowth and regeneration via mTOR activation.
Ma C, Teng L, Lin G, Guo B, Zhuo R, Qian X, Guan T, Wu R, Liu Y, Liu M
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 May;35(5):e21526
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 May;35(5):e21526
TUFM is involved in Alzheimer's disease-like pathologies that are associated with ROS.
Zhong BR, Zhou GF, Song L, Wen QX, Deng XJ, Ma YL, Hu LT, Chen GJ
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 May;35(5):e21445
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 May;35(5):e21445
BALB/c mice infected with Angiostrongylus cantonensis: A new model for demyelination in the brain.
Xiong H, Zhou Z, Wu Z, Feng Y, Xie F
Anatomical record (Hoboken, N.J. : 2007) 2021 May;304(5):1084-1093
Anatomical record (Hoboken, N.J. : 2007) 2021 May;304(5):1084-1093
Porcine TRIM21 RING-finger E3 ubiquitin ligase is essential for anti-PRRSV activity.
Wei Y, Zeng S, Zou C, Zhang H, Peng O, Xue C, Cao Y
Veterinary microbiology 2021 May;256:109043
Veterinary microbiology 2021 May;256:109043
RAGE: A potential therapeutic target during FGF1 treatment of diabetes-mediated liver injury.
Zheng P, Tang Z, Xiong J, Wang B, Xu J, Chen L, Cai S, Wu C, Ye L, Xu K, Chen Z, Wu Y, Xiao J
Journal of cellular and molecular medicine 2021 May;25(10):4776-4785
Journal of cellular and molecular medicine 2021 May;25(10):4776-4785
Zebrafish hhatla is involved in cardiac hypertrophy.
Shi X, Zhang Y, Gong Y, Chen M, Brand-Arzamendi K, Liu X, Wen XY
Journal of cellular physiology 2021 May;236(5):3700-3709
Journal of cellular physiology 2021 May;236(5):3700-3709
Podocyte apoptosis in diabetic nephropathy by BASP1 activation of the p53 pathway via WT1.
Zhang Y, Xu C, Ye Q, Tong L, Jiang H, Zhu X, Huang L, Lin W, Fu H, Wang J, Persson PB, Lai EY, Mao J
Acta physiologica (Oxford, England) 2021 May;232(1):e13634
Acta physiologica (Oxford, England) 2021 May;232(1):e13634
LIMIT is an immunogenic lncRNA in cancer immunity and immunotherapy.
Li G, Kryczek I, Nam J, Li X, Li S, Li J, Wei S, Grove S, Vatan L, Zhou J, Du W, Lin H, Wang T, Subramanian C, Moon JJ, Cieslik M, Cohen M, Zou W
Nature cell biology 2021 May;23(5):526-537
Nature cell biology 2021 May;23(5):526-537
Exosomal microRNA-301a-3p promotes the proliferation and invasion of nasopharyngeal carcinoma cells by targeting BTG1 mRNA.
Cheng Q, Li Q, Xu L, Jiang H
Molecular medicine reports 2021 May;23(5)
Molecular medicine reports 2021 May;23(5)
Regulatory role of the TLR4/JNK signaling pathway in sepsis‑induced myocardial dysfunction.
Chang C, Hu L, Sun S, Song Y, Liu S, Wang J, Li P
Molecular medicine reports 2021 May;23(5)
Molecular medicine reports 2021 May;23(5)
Protective effects of curcumin against rat intestinal inflammation‑related motility disorders.
Yao Y, Luo R, Xiong S, Zhang C, Zhang Y
Molecular medicine reports 2021 May;23(5)
Molecular medicine reports 2021 May;23(5)
The DpdtbA induced EMT inhibition in gastric cancer cell lines was through ferritinophagy-mediated activation of p53 and PHD2/hif-1α pathway.
Guan D, Li C, Li Y, Li Y, Wang G, Gao F, Li C
Journal of inorganic biochemistry 2021 May;218:111413
Journal of inorganic biochemistry 2021 May;218:111413
Role of vasodilator-stimulated phosphoprotein in RANKL-differentiated murine macrophage RAW264.7 cells: Modulation of NF-κB, c-Fos and NFATc1 transcription factors.
Hu H, Li C, Zhang H, Wu G, Huang Y
Experimental and therapeutic medicine 2021 May;21(5):412
Experimental and therapeutic medicine 2021 May;21(5):412
Synergistic effects of olaparib combined with ERCC1 on the sensitivity of cisplatin in non-small cell lung cancer.
Xie K, Ni X, Lv S, Zhou G, He H
Oncology letters 2021 May;21(5):365
Oncology letters 2021 May;21(5):365
Promoting roles of KLF5 in myocardial infarction in mice involving microRNA-27a suppression and the following GFPT2/TGF-β/Smad2/3 axis activation.
Tian Z, Zhang Y, Lyu X
Cell cycle (Georgetown, Tex.) 2021 May;20(9):874-893
Cell cycle (Georgetown, Tex.) 2021 May;20(9):874-893
Gut-Lung Dysbiosis Accompanied by Diabetes Mellitus Leads to Pulmonary Fibrotic Change through the NF-κB Signaling Pathway.
Wang G, Hu YX, He MY, Xie YH, Su W, Long D, Zhao R, Wang J, Dai C, Li H, Si ZP, Cheng X, Li RM, Li Z, Yang X
The American journal of pathology 2021 May;191(5):838-856
The American journal of pathology 2021 May;191(5):838-856
Integrated transcriptomics and epigenomics reveal chamber-specific and species-specific characteristics of human and mouse hearts.
Gao J, Zheng Y, Li L, Lu M, Chen X, Wang Y, Li Y, Liu X, Gao Y, Mao Y, Zhao P, Zhang J, Tang F, Song L, Wen L, Wang J
PLoS biology 2021 May;19(5):e3001229
PLoS biology 2021 May;19(5):e3001229
Knockdown of the mRNA encoding the ribosomal protein eL38 in mammalian cells causes a substantial reorganization of genomic transcription.
Gopanenko AV, Kolobova AV, Meschaninova MI, Venyaminova AG, Tupikin AE, Kabilov MR, Malygin AA, Karpova GG
Biochimie 2021 May;184:132-142
Biochimie 2021 May;184:132-142
Mitochondrial TXN2 attenuates amyloidogenesis via selective inhibition of BACE1 expression.
Li KY, Xiang XJ, Song L, Chen J, Luo B, Wen QX, Zhong BR, Zhou GF, Deng XJ, Ma YL, Hu LT, Chen GJ
Journal of neurochemistry 2021 May;157(4):1351-1365
Journal of neurochemistry 2021 May;157(4):1351-1365
α-synuclein abnormalities trigger focal tau pathology, spreading to various brain areas in Parkinson disease.
Hadi F, Akrami H, Totonchi M, Barzegar A, Nabavi SM, Shahpasand K
Journal of neurochemistry 2021 May;157(3):727-751
Journal of neurochemistry 2021 May;157(3):727-751
Toxicological and physiological effects of successive exposure to ochratoxin A at food regulatory limits.
Wei W, Liu C, Ke P, Chen X, Zhou T, Xu J, Zhou Y
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2021 May;151:112128
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2021 May;151:112128
Identification of differentially expressed proteins between fused and open sutures in sagittal nonsyndromic craniosynostosis during suture development by quantitative proteomic analysis.
Bala K, Cuellar A, Herren AW, Boyadjiev SA
Proteomics. Clinical applications 2021 May;15(2-3):e2000031
Proteomics. Clinical applications 2021 May;15(2-3):e2000031
Qingjie Fuzheng Granule suppresses lymphangiogenesis in colorectal cancer via the VEGF-C/VEGFR-3 dependent PI3K/AKT pathway.
Huang B, Lu Y, Gui M, Guan J, Lin M, Zhao J, Mao Q, Lin J
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 May;137:111331
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 May;137:111331
The Kidney-Related Effects of Polystyrene Microplastics on Human Kidney Proximal Tubular Epithelial Cells HK-2 and Male C57BL/6 Mice.
Wang YL, Lee YH, Hsu YH, Chiu IJ, Huang CC, Huang CC, Chia ZC, Lee CP, Lin YF, Chiu HW
Environmental health perspectives 2021 May;129(5):57003
Environmental health perspectives 2021 May;129(5):57003
The clinical significance, prognostic value and biological role of lncRNA LINC01793 in oral squamous cell carcinoma.
Yuan SJ, Li SY, Wang YH, Zhang HF, Hua Y, Wang T
Archives of oral biology 2021 May;125:105105
Archives of oral biology 2021 May;125:105105
Tracing production instability in a clonally derived CHO cell line using single-cell transcriptomics.
Tzani I, Herrmann N, Carillo S, Spargo CA, Hagan R, Barron N, Bones J, Shannon Dillmore W, Clarke C
Biotechnology and bioengineering 2021 May;118(5):2016-2030
Biotechnology and bioengineering 2021 May;118(5):2016-2030
The critical role of ZP genes in female infertility characterized by empty follicle syndrome and oocyte degeneration.
Yang P, Chen T, Liu Y, Hou Z, Wu K, Cao Y, Zhang J, Wang Z, Zhao H
Fertility and sterility 2021 May;115(5):1259-1269
Fertility and sterility 2021 May;115(5):1259-1269
SMYD3-PARP16 axis accelerates unfolded protein response and mediates neointima formation.
Long F, Yang D, Wang J, Wang Q, Ni T, Wei G, Zhu Y, Liu X
Acta pharmaceutica Sinica. B 2021 May;11(5):1261-1273
Acta pharmaceutica Sinica. B 2021 May;11(5):1261-1273
PD-L1 combined with HDAC9 is a useful prognostic predictor in hepatocellular carcinoma.
Yang Z, Zhang L, Liu J, Yang L, Xue H, Bai S, Wang K
Translational cancer research 2021 May;10(5):2305-2317
Translational cancer research 2021 May;10(5):2305-2317
miR-140-3p inhibits colorectal cancer progression and its liver metastasis by targeting BCL9 and BCL2.
Liu D, Chen C, Cui M, Zhang H
Cancer medicine 2021 May;10(10):3358-3372
Cancer medicine 2021 May;10(10):3358-3372
The near-infrared dye IR-61 restores erectile function in a streptozotocin-induced diabetes model via mitochondrial protection.
Yue XF, Shen CX, Wang JW, Dai LY, Fang Q, Long L, Zhi Y, Li XR, Wang YW, Shen GF, Liu ZJ, Shi CM, Li WB
Asian journal of andrology 2021 May-Jun;23(3):249-258
Asian journal of andrology 2021 May-Jun;23(3):249-258
G-Protein-coupled Estrogen Receptor 1 Agonist G-1 Perturbs Sunitinib Resistance-related Phosphoproteomic Signatures in Renal Cell Carcinoma.
Chen SK, Wang YC, Lin TY, Wu HJ, Huang CJ, Ku WC
Cancer genomics & proteomics 2021 May-Jun;18(3):207-220
Cancer genomics & proteomics 2021 May-Jun;18(3):207-220
Silencing TAK1 reduces MAPKs-MMP2/9 expression to reduce inflammation-driven neurohistological disruption post spinal cord injury.
Jiang S, Wu Y, Wu S, Ye S, Kong R, Chang J, Xia M, Bao J, Peng X, Hong X, Qian Z, Li H
Cell death discovery 2021 May 8;7(1):96
Cell death discovery 2021 May 8;7(1):96
BCL7C suppresses ovarian cancer growth by inactivating mutant p53.
Huang C, Hao Q, Shi G, Zhou X, Zhang Y
Journal of molecular cell biology 2021 May 7;13(2):141-150
Journal of molecular cell biology 2021 May 7;13(2):141-150
Time-resolved proteomics profiling of the ciliary Hedgehog response.
May EA, Kalocsay M, D'Auriac IG, Schuster PS, Gygi SP, Nachury MV, Mick DU
The Journal of cell biology 2021 May 3;220(5)
The Journal of cell biology 2021 May 3;220(5)
FIT2 organizes lipid droplet biogenesis with ER tubule-forming proteins and septins.
Chen F, Yan B, Ren J, Lyu R, Wu Y, Guo Y, Li D, Zhang H, Hu J
The Journal of cell biology 2021 May 3;220(5)
The Journal of cell biology 2021 May 3;220(5)
miR-132 mediates cell permeability and migration by targeting occludin in high-glucose -induced ARPE-19 cells.
Wang SS, Liao X, Liu F, Zhang Q, Qiu JJ, Fu SH
Endocrine journal 2021 May 28;68(5):531-541
Endocrine journal 2021 May 28;68(5):531-541
Neocortex- and hippocampus-specific deletion of Gabrg2 causes temperature-dependent seizures in mice.
Li X, Guo S, Xu S, Chen Z, Wang L, Ding J, Huo J, Xiao L, He Z, Jin Z, Wang F, Sun T
Cell death & disease 2021 May 28;12(6):553
Cell death & disease 2021 May 28;12(6):553
Vertebrate cells differentially interpret ciliary and extraciliary cAMP.
Truong ME, Bilekova S, Choksi SP, Li W, Bugaj LJ, Xu K, Reiter JF
Cell 2021 May 27;184(11):2911-2926.e18
Cell 2021 May 27;184(11):2911-2926.e18
Mitocytosis, a migrasome-mediated mitochondrial quality-control process.
Jiao H, Jiang D, Hu X, Du W, Ji L, Yang Y, Li X, Sho T, Wang X, Li Y, Wu YT, Wei YH, Hu X, Yu L
Cell 2021 May 27;184(11):2896-2910.e13
Cell 2021 May 27;184(11):2896-2910.e13
SEC61G promotes breast cancer development and metastasis via modulating glycolysis and is transcriptionally regulated by E2F1.
Ma J, He Z, Zhang H, Zhang W, Gao S, Ni X
Cell death & disease 2021 May 27;12(6):550
Cell death & disease 2021 May 27;12(6):550
Protective Effects of Fucoxanthin on Hydrogen Peroxide-Induced Calcification of Heart Valve Interstitial Cells.
Chiang YF, Tsai CH, Chen HY, Wang KL, Chang HY, Huang YJ, Hong YH, Ali M, Shieh TM, Huang TC, Lin CI, Hsia SM
Marine drugs 2021 May 26;19(6)
Marine drugs 2021 May 26;19(6)
The SUN1-SPDYA interaction plays an essential role in meiosis prophase I.
Chen Y, Wang Y, Chen J, Zuo W, Fan Y, Huang S, Liu Y, Chen G, Li Q, Li J, Wu J, Bian Q, Huang C, Lei M
Nature communications 2021 May 26;12(1):3176
Nature communications 2021 May 26;12(1):3176
STIP1 knockdown suppresses colorectal cancer cell proliferation, migration and invasion by inhibiting STAT3 pathway.
Xia Y, Chen J, Liu G, Huang W, Wei X, Wei Z, He Y
Chemico-biological interactions 2021 May 25;341:109446
Chemico-biological interactions 2021 May 25;341:109446
circ-PTK2 (hsa_circ_0008305) regulates the pathogenic processes of ovarian cancer via miR-639 and FOXC1 regulatory cascade.
Wu SG, Zhou P, Chen JX, Lei J, Hua L, Dong Y, Hu M, Lian CL, Yang LC, Zhou J
Cancer cell international 2021 May 25;21(1):277
Cancer cell international 2021 May 25;21(1):277
Activation of the STAT3 Signaling Pathway by the RNA-Dependent RNA Polymerase Protein of Arenavirus.
Wang Q, Xin Q, Shang W, Wan W, Xiao G, Zhang LK
Viruses 2021 May 25;13(6)
Viruses 2021 May 25;13(6)
OTUD7B stabilizes estrogen receptor α and promotes breast cancer cell proliferation.
Tang J, Wu Z, Tian Z, Chen W, Wu G
Cell death & disease 2021 May 25;12(6):534
Cell death & disease 2021 May 25;12(6):534
Splicing factor SRSF6 mediates pleural fibrosis.
Liang LM, Xiong L, Cheng PP, Chen SJ, Feng X, Zhou YY, Niu Q, Wang M, Chen Q, Song LJ, Yu F, He XL, Xiang F, Wang X, Ye H, Ma WL
JCI insight 2021 May 24;6(10)
JCI insight 2021 May 24;6(10)
The viral restriction factor tetherin/BST2 tethers cytokinetic midbody remnants to the cell surface.
Presle A, Frémont S, Salles A, Commere PH, Sassoon N, Berlioz-Torrent C, Gupta-Rossi N, Echard A
Current biology : CB 2021 May 24;31(10):2203-2213.e5
Current biology : CB 2021 May 24;31(10):2203-2213.e5
Downregulation of CD151 restricts VCAM-1 mediated leukocyte infiltration to reduce neurobiological injuries after experimental stroke.
Gao C, Jia W, Xu W, Wu Q, Wu J
Journal of neuroinflammation 2021 May 22;18(1):118
Journal of neuroinflammation 2021 May 22;18(1):118
miR-338-3p inhibits autophagy in a rat model of allergic rhinitis after PM2.5 exposure through AKT/mTOR signaling by targeting UBE2Q1.
Wang JC, Huang Y, Zhang RX, Han ZJ, Zhou LL, Sun N, Dong WY, Zhuang GS
Biochemical and biophysical research communications 2021 May 21;554:1-6
Biochemical and biophysical research communications 2021 May 21;554:1-6
Long non-coding RNA SNHG14 aggravates LPS-induced acute kidney injury through regulating miR-495-3p/HIPK1.
Yang N, Wang H, Zhang L, Lv J, Niu Z, Liu J, Zhang Z
Acta biochimica et biophysica Sinica 2021 May 21;53(6):719-728
Acta biochimica et biophysica Sinica 2021 May 21;53(6):719-728
SAA1/TLR2 axis directs chemotactic migration of hepatic stellate cells responding to injury.
Getachew A, Abbas N, You K, Yang Z, Hussain M, Huang X, Cheng Z, Tan S, Tao J, Yu X, Chen Y, Yang F, Pan T, Xu Y, Xu G, Zhuang Y, Wu F, Li Y
iScience 2021 May 21;24(5):102483
iScience 2021 May 21;24(5):102483
Amphiphysin I cleavage by asparagine endopeptidase leads to tau hyperphosphorylation and synaptic dysfunction.
Zhang X, Zou L, Meng L, Xiong M, Pan L, Chen G, Zheng Y, Xiong J, Wang Z, Duong DM, Zhang Z, Cao X, Wang T, Tang L, Ye K, Zhang Z
eLife 2021 May 21;10
eLife 2021 May 21;10
Ganoderma lucidum stimulates autophagy-dependent longevity pathways in Caenorhabditis elegans and human cells.
Peng HH, Wu CY, Hsiao YC, Martel J, Ke PY, Chiu CY, Liau JC, Chang IT, Su YH, Ko YF, Young JD, Ojcius DM
Aging 2021 May 20;13(10):13474-13495
Aging 2021 May 20;13(10):13474-13495
LncRNA CD27-AS1 promotes acute myeloid leukemia progression through the miR-224-5p/PBX3 signaling circuit.
Tao Y, Zhang J, Chen L, Liu X, Yao M, Zhang H
Cell death & disease 2021 May 18;12(6):510
Cell death & disease 2021 May 18;12(6):510
Heme cytotoxicity is the consequence of endoplasmic reticulum stress in atherosclerotic plaque progression.
Pethő D, Hendrik Z, Nagy A, Beke L, Patsalos A, Nagy L, Póliska S, Méhes G, Tóth C, Potor L, Eaton JW, Jacob HS, Balla G, Balla J, Gáll T
Scientific reports 2021 May 17;11(1):10435
Scientific reports 2021 May 17;11(1):10435
LncRNA ZNF674-AS1 regulates granulosa cell glycolysis and proliferation by interacting with ALDOA.
Li D, Wang X, Li G, Dang Y, Zhao S, Qin Y
Cell death discovery 2021 May 16;7(1):107
Cell death discovery 2021 May 16;7(1):107
YTHDF1 Promotes Gastric Carcinogenesis by Controlling Translation of FZD7.
Pi J, Wang W, Ji M, Wang X, Wei X, Jin J, Liu T, Qiang J, Qi Z, Li F, Liu Y, Ma Y, Si Y, Huo Y, Gao Y, Chen Y, Dong L, Su R, Chen J, Rao S, Yi P, Yu S, Wang F, Yu J
Cancer research 2021 May 15;81(10):2651-2665
Cancer research 2021 May 15;81(10):2651-2665
BMI1 regulates multiple myeloma-associated macrophage's pro-myeloma functions.
Zhang D, Huang J, Wang F, Ding H, Cui Y, Yang Y, Xu J, Luo H, Gao Y, Pan L, Wu Y, Gong Y, Xie L, Liu Z, Qu Y, Zhang L, Liu W, Zhang W, Zhao S, Yi Q, Niu T, Zheng Y
Cell death & disease 2021 May 15;12(5):495
Cell death & disease 2021 May 15;12(5):495
Asenapine maleate inhibits angiotensin II-induced proliferation and activation of cardiac fibroblasts via the ROS/TGFβ1/MAPK signaling pathway.
Wu HH, Meng TT, Chen JM, Meng FL, Wang SY, Liu RH, Chen JN, Ning B, Li Y, Su GH
Biochemical and biophysical research communications 2021 May 14;553:172-179
Biochemical and biophysical research communications 2021 May 14;553:172-179
Ferritin disorder in the plasma and hippocampus associated with major depressive disorder.
Wang Y, Li Y, Wu Z, Chen Z, Yu H, He Y, Tian Y, Lan T, Bai M, Chen X, Cheng K, Xie P
Biochemical and biophysical research communications 2021 May 14;553:114-118
Biochemical and biophysical research communications 2021 May 14;553:114-118
Hyperactivation of HER2-SHCBP1-PLK1 axis promotes tumor cell mitosis and impairs trastuzumab sensitivity to gastric cancer.
Shi W, Zhang G, Ma Z, Li L, Liu M, Qin L, Yu Z, Zhao L, Liu Y, Zhang X, Qin J, Ye H, Jiang X, Zhou H, Sun H, Jiao Z
Nature communications 2021 May 14;12(1):2812
Nature communications 2021 May 14;12(1):2812
Endothelial genetic deletion of CD147 induces changes in the dual function of the blood-brain barrier and is implicated in Alzheimer's disease.
Wang H, Lv JJ, Zhao Y, Wei HL, Zhang TJ, Yang HJ, Chen ZN, Jiang JL
CNS neuroscience & therapeutics 2021 May 13;27(9):1048-63
CNS neuroscience & therapeutics 2021 May 13;27(9):1048-63
Interactions between Autophagy, Proinflammatory Cytokines, and Apoptosis in Neuropathic Pain: Granulocyte Colony Stimulating Factor as a Multipotent Therapy in Rats with Chronic Constriction Injury.
Liao MF, Yeh SR, Lu KT, Hsu JL, Chao PK, Hsu HC, Peng CH, Lee YL, Hung YH, Ro LS
Biomedicines 2021 May 12;9(5)
Biomedicines 2021 May 12;9(5)
Antifungal Activity of Quinofumelin against Fusarium graminearum and Its Inhibitory Effect on DON Biosynthesis.
Xiu Q, Bi L, Xu H, Li T, Zhou Z, Li Z, Wang J, Duan Y, Zhou M
Toxins 2021 May 12;13(5)
Toxins 2021 May 12;13(5)
Zuojin Pill ameliorates chronic atrophic gastritis induced by MNNG through TGF-β1/PI3K/Akt axis.
Tong Y, Wang R, Liu X, Tian M, Wang Y, Cui Y, Zou W, Zhao Y
Journal of ethnopharmacology 2021 May 10;271:113893
Journal of ethnopharmacology 2021 May 10;271:113893
Formation of fibrin at sights of conceptus adhesion in the ewe.
Matsuno Y, Amin YA, Kusama K, Imakawa K
Reproduction (Cambridge, England) 2021 May 10;161(6):709-720
Reproduction (Cambridge, England) 2021 May 10;161(6):709-720
Tryptanthrin Regulates Vascular Smooth Muscle Cell Phenotypic Switching in Atherosclerosis by AMP-Activated Protein Kinase/Acetyl-CoA Carboxylase Signaling Pathway.
Shi X, Zhang Y, Han J, Peng W, Fang Z, Qin Y, Xu X, Lin J, Xiao F, Zhao L, Lin Y
Journal of cardiovascular pharmacology 2021 May 1;77(5):642-649
Journal of cardiovascular pharmacology 2021 May 1;77(5):642-649
LRRC4 functions as a neuron-protective role in experimental autoimmune encephalomyelitis.
Zhang Y, Li D, Zeng Q, Feng J, Fu H, Luo Z, Xiao B, Yang H, Wu M
Molecular medicine (Cambridge, Mass.) 2021 May 1;27(1):44
Molecular medicine (Cambridge, Mass.) 2021 May 1;27(1):44
Psoralidin, a major component of Psoraleae Fructus, induces inflammasome activation and idiosyncratic liver injury.
Wang Y, Xu G, Wang Z, Li R, Zhan X, Liu H, Qin Q, Li W, Wang X, Zhang M, Tang J, Bai Z, Xiao X
International immunopharmacology 2021 Mar;92:107352
International immunopharmacology 2021 Mar;92:107352
Hypoxia enhances the production and antitumor effect of exosomes derived from natural killer cells.
Jiang Y, Jiang H, Wang K, Liu C, Man X, Fu Q
Annals of translational medicine 2021 Mar;9(6):473
Annals of translational medicine 2021 Mar;9(6):473
Arginine methyltransferase PRMT5 negatively regulates cGAS-mediated antiviral immune response.
Ma D, Yang M, Wang Q, Sun C, Shi H, Jing W, Bi Y, Shen X, Ma X, Qin Z, Lin Y, Zhu L, Zhao Y, Cheng Y, Han L
Science advances 2021 Mar;7(13)
Science advances 2021 Mar;7(13)
The cryo-EM structure of an ERAD protein channel formed by tetrameric human Derlin-1.
Rao B, Li S, Yao D, Wang Q, Xia Y, Jia Y, Shen Y, Cao Y
Science advances 2021 Mar;7(10)
Science advances 2021 Mar;7(10)
Trim47 overexpression correlates with poor prognosis in gastric cancer.
Xia Y, Wei Z, Huang W, Wei X, He Y
Neoplasma 2021 Mar;68(2):307-316
Neoplasma 2021 Mar;68(2):307-316
Decreased miR-214-3p activates NF-κB pathway and aggravates osteoarthritis progression.
Cao Y, Tang S, Nie X, Zhou Z, Ruan G, Han W, Zhu Z, Ding C
EBioMedicine 2021 Mar;65:103283
EBioMedicine 2021 Mar;65:103283
Total flavone extract from Ampelopsis megalophylla induces apoptosis in the MCF‑7 cell line.
Gui C, Zhang C, Xiong X, Huang J, Xi J, Gong L, Huang B, Zhang X
International journal of oncology 2021 Mar;58(3):409-418
International journal of oncology 2021 Mar;58(3):409-418
Biological testing of chitosan-collagen-based porous scaffolds loaded with PLGA/Triamcinolone microspheres for ameliorating endoscopic dissection-related stenosis in oesophagus.
Ni W, Lin S, Bian S, Xiao M, Wang Y, Yang Y, Lu C, Zheng W, Zhou P
Cell proliferation 2021 Mar;54(3):e13004
Cell proliferation 2021 Mar;54(3):e13004
Sirtuin 1 ameliorates defenestration in hepatic sinusoidal endothelial cells during liver fibrosis via inhibiting stress-induced premature senescence.
Luo X, Bai Y, He S, Sun S, Jiang X, Yang Z, Lu D, Wei P, Liang Y, Peng C, Wang Y, Sheng R, Han S, Li X, Zhang B
Cell proliferation 2021 Mar;54(3):e12991
Cell proliferation 2021 Mar;54(3):e12991
RNA m6A Modification Alteration by Black Phosphorus Quantum Dots Regulates Cell Ferroptosis: Implications for Nanotoxicological Assessment.
Ruan F, Zeng J, Yin H, Jiang S, Cao X, Zheng N, Han C, Zhang C, Zuo Z, He C
Small methods 2021 Mar;5(3):e2001045
Small methods 2021 Mar;5(3):e2001045
miR‑106b‑5p targeting SIX1 inhibits TGF‑β1‑induced pulmonary fibrosis and epithelial‑mesenchymal transition in asthma through regulation of E2F1.
Liu S, Chen X, Zhang S, Wang X, Du X, Chen J, Zhou G
International journal of molecular medicine 2021 Mar;47(3)
International journal of molecular medicine 2021 Mar;47(3)
VSP‑17 suppresses the migration and invasion of triple‑negative breast cancer cells through inhibition of the EMT process via the PPARγ/AMPK signaling pathway.
Xu X, Liu M, Yang Y, Wei C, Zhang X, Song H, Wang Y, Duan X
Oncology reports 2021 Mar;45(3):975-986
Oncology reports 2021 Mar;45(3):975-986
Nucleolar and spindle‑associated protein 1 promotes non‑small cell lung cancer progression and serves as an effector of myocyte enhancer factor 2D.
Ling B, Wei P, Xiao J, Cen B, Wei H, Feng X, Ye G, Li S, Zhang Z, Liang W, Huang S, Huang W
Oncology reports 2021 Mar;45(3):1044-1058
Oncology reports 2021 Mar;45(3):1044-1058
20(S)-ginsenoside Rh2 induces caspase-dependent promyelocytic leukemia-retinoic acid receptor A degradation in NB4 cells via Akt/Bax/caspase9 and TNF-α/caspase8 signaling cascades.
Zhu S, Liu X, Xue M, Li Y, Cai D, Wang S, Zhang L
Journal of ginseng research 2021 Mar;45(2):295-304
Journal of ginseng research 2021 Mar;45(2):295-304
Abnormal cGMP-dependent protein kinase I-mediated decidualization in preeclampsia.
Chen J, Ren W, Lin L, Zeng S, Huang L, Tang J, Bi S, Pan J, Chen D, Du L
Hypertension research : official journal of the Japanese Society of Hypertension 2021 Mar;44(3):318-324
Hypertension research : official journal of the Japanese Society of Hypertension 2021 Mar;44(3):318-324
KLF4 initiates sustained YAP activation to promote renal fibrosis in mice after ischemia-reperfusion kidney injury.
Xu D, Chen PP, Zheng PQ, Yin F, Cheng Q, Zhou ZL, Xie HY, Li JY, Ni JY, Wang YZ, Chen SJ, Zhou L, Wang XX, Liu J, Zhang W, Lu LM
Acta pharmacologica Sinica 2021 Mar;42(3):436-450
Acta pharmacologica Sinica 2021 Mar;42(3):436-450
miR-30a-5p Inhibits Epithelial-to-Mesenchymal Transition by Targeting CDK6 in Nasal Polyps.
Zhang T, Zhou Y, You B, You Y, Yan Y, Zhang J, Pei Y, Zhang W, Chen J
American journal of rhinology & allergy 2021 Mar;35(2):152-163
American journal of rhinology & allergy 2021 Mar;35(2):152-163
Oncogenic AURKA-enhanced N(6)-methyladenosine modification increases DROSHA mRNA stability to transactivate STC1 in breast cancer stem-like cells.
Peng F, Xu J, Cui B, Liang Q, Zeng S, He B, Zou H, Li M, Zhao H, Meng Y, Chen J, Liu B, Lv S, Chu P, An F, Wang Z, Huang J, Zhan Y, Liao Y, Lu J, Xu L, Zhang J, Sun Z, Li Z, Wang F, Lam EW, Liu Q
Cell research 2021 Mar;31(3):345-361
Cell research 2021 Mar;31(3):345-361
NFAT Overexpression Correlates with CA72-4 and Poor Prognosis of Ovarian Clear-Cell Carcinoma Subtype.
Xin B, Ji KQ, Liu YS, Zhao XD
Reproductive sciences (Thousand Oaks, Calif.) 2021 Mar;28(3):745-756
Reproductive sciences (Thousand Oaks, Calif.) 2021 Mar;28(3):745-756
TRF2 recruits nucleolar protein TCOF1 to coordinate telomere transcription and replication.
Nie X, Xiao D, Ge Y, Xie Y, Zhou H, Zheng T, Li X, Liu H, Huang H, Zhao Y
Cell death and differentiation 2021 Mar;28(3):1062-1075
Cell death and differentiation 2021 Mar;28(3):1062-1075
Histone deacetylase 3 aberration inhibits Klotho transcription and promotes renal fibrosis.
Chen F, Gao Q, Wei A, Chen X, Shi Y, Wang H, Cao W
Cell death and differentiation 2021 Mar;28(3):1001-1012
Cell death and differentiation 2021 Mar;28(3):1001-1012
Activation of NRF2/FPN1 pathway attenuates myocardial ischemia-reperfusion injury in diabetic rats by regulating iron homeostasis and ferroptosis.
Tian H, Xiong Y, Zhang Y, Leng Y, Tao J, Li L, Qiu Z, Xia Z
Cell stress & chaperones 2021 Mar;27(2):149-164
Cell stress & chaperones 2021 Mar;27(2):149-164
Chondrocyte ferroptosis contribute to the progression of osteoarthritis.
Yao X, Sun K, Yu S, Luo J, Guo J, Lin J, Wang G, Guo Z, Ye Y, Guo F
Journal of orthopaedic translation 2021 Mar;27:33-43
Journal of orthopaedic translation 2021 Mar;27:33-43
Gambogic acid ameliorates high glucose- and palmitic acid-induced inflammatory response in ARPE-19 cells via activating Nrf2 signaling pathway: ex vivo.
Chen J, Li L, Zhou Y, Zhang J, Chen L
Cell stress & chaperones 2021 Mar;26(2):367-375
Cell stress & chaperones 2021 Mar;26(2):367-375
AIMP3 inhibits cell growth and metastasis of lung adenocarcinoma through activating a miR-96-5p-AIMP3-p53 axis.
Ding L, Fang Y, Li Y, Hu Q, Ai M, Deng K, Huang X, Xin H
Journal of cellular and molecular medicine 2021 Mar;25(6):3019-3030
Journal of cellular and molecular medicine 2021 Mar;25(6):3019-3030
CRKL promotes hepatocarcinoma through enhancing glucose metabolism of cancer cells via activating PI3K/Akt.
Guo C, Gao C, Lv X, Zhao D, Greenaway FT, Hao L, Tian Y, Liu S, Sun MZ
Journal of cellular and molecular medicine 2021 Mar;25(5):2714-2724
Journal of cellular and molecular medicine 2021 Mar;25(5):2714-2724
P53 regulation of osteoblast differentiation is mediated through specific microRNAs.
Shah S, Pendleton E, Couture O, Broachwalla M, Kusper T, Alt LAC, Fay MJ, Chandar N
Biochemistry and biophysics reports 2021 Mar;25:100920
Biochemistry and biophysics reports 2021 Mar;25:100920
SHARPIN stabilizes β-catenin through a linear ubiquitination-independent manner to support gastric tumorigenesis.
Zhang L, Liu Q, Liu KW, Qin ZY, Zhu GX, Shen LT, Zhang N, Liu BY, Che LR, Li JY, Wang T, Wen LZ, Liu KJ, Guo Y, Yin XR, Wang XW, Zhou ZH, Xiao HL, Cui YH, Bian XW, Lan CH, Chen D, Wang B
Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association 2021 Mar;24(2):402-416
Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association 2021 Mar;24(2):402-416
α5-nAChR and survivin: Two potential biological targets in lung adenocarcinoma.
Zhang Y, Sun Y, Jia Y, Zhang Q, Zhu P, Ma X
Journal of cellular physiology 2021 Mar;236(3):1787-1797
Journal of cellular physiology 2021 Mar;236(3):1787-1797
Zenglv Fumai Granule protects cardiomyocytes against hypoxia/reoxygenation-induced apoptosis via inhibiting TRIM28 expression.
Zhang XH, Zhao HY, Wang Y, Di L, Liu XY, Qian F, Liu SR
Molecular medicine reports 2021 Mar;23(3)
Molecular medicine reports 2021 Mar;23(3)
Genetic response to low‑intensity ultrasound on mouse ST2 bone marrow stromal cells.
Tabuchi Y, Hasegawa H, Suzuki N, Furusawa Y, Hirano T, Nagaoka R, Hirayama J, Hoshi N, Mochizuki T
Molecular medicine reports 2021 Mar;23(3)
Molecular medicine reports 2021 Mar;23(3)
Emodin enhances cisplatin sensitivity in non-small cell lung cancer through Pgp downregulation.
Peng S, Wang J, Lu C, Xu Z, Chai JJ, Ke Q, Deng XZ
Oncology letters 2021 Mar;21(3):230
Oncology letters 2021 Mar;21(3):230
Decreased Expression of Heat Shock Protein 47 Is Associated with T-2 Toxin and Low Selenium-Induced Matrix Degradation in Cartilages of Kashin-Beck Disease.
Zhang M, Wang M, Wang H, Zhang Y, Li Z, Feng Y, Liu Y, Liu Y, Liao Y, Wang W, Fang Q, Chen J
Biological trace element research 2021 Mar;199(3):944-954
Biological trace element research 2021 Mar;199(3):944-954
Two loss-of-function ANKRD11 variants in Chinese patients with short stature and a possible molecular pathway.
Zhang T, Yang Y, Yin X, Wang X, Ni J, Dong Z, Li C, Lu W
American journal of medical genetics. Part A 2021 Mar;185(3):710-718
American journal of medical genetics. Part A 2021 Mar;185(3):710-718
Nuciferine protects against folic acid-induced acute kidney injury by inhibiting ferroptosis.
Li D, Liu B, Fan Y, Liu M, Han B, Meng Y, Xu X, Song Z, Liu X, Hao Q, Duan X, Nakai A, Chang Y, Cao P, Tan K
British journal of pharmacology 2021 Mar;178(5):1182-1199
British journal of pharmacology 2021 Mar;178(5):1182-1199
JMJD6 negatively regulates cytosolic RNA induced antiviral signaling by recruiting RNF5 to promote activated IRF3 K48 ubiquitination.
Zhang W, Wang Q, Yang F, Zhu Z, Duan Y, Yang Y, Cao W, Zhang K, Ma J, Liu X, Zheng H
PLoS pathogens 2021 Mar;17(3):e1009366
PLoS pathogens 2021 Mar;17(3):e1009366
CITED4 mediates proliferation, apoptosis and steroidogenesis of Hu sheep granulosa cells in vitro.
Yao X, Ei-Samahy MA, Xiao S, Wang Z, Meng F, Li X, Bao Y, Zhang Y, Wang Z, Fan Y, Wang F
Reproduction (Cambridge, England) 2021 Mar;161(3):255-267
Reproduction (Cambridge, England) 2021 Mar;161(3):255-267
Babao Dan improves neurocognitive function by inhibiting inflammation in clinical minimal hepatic encephalopathy.
Lu B, Wu C, Azami NLB, Xie D, Zhao C, Xu W, Hui D, Chen X, Sun R, Song J, An Y, Li K, Wang H, Ye G, Sun M
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Mar;135:111084
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Mar;135:111084
DZNep attenuates allergic airway inflammation in an ovalbumin-induced murine model.
Li H, Li J, Lu T, Chen D, Xu R, Sun W, Luo X, Li H, Ma R, Wen W
Molecular immunology 2021 Mar;131:60-67
Molecular immunology 2021 Mar;131:60-67
Radiotherapy programs neutrophils to an antitumor phenotype by inducing mesenchymal-epithelial transition.
Liu Q, Hao Y, Du R, Hu D, Xie J, Zhang J, Deng G, Liang N, Tian T, Käsmann L, Rades D, Rim CH, Hu P, Zhang J
Translational lung cancer research 2021 Mar;10(3):1424-1443
Translational lung cancer research 2021 Mar;10(3):1424-1443
Annexin A7 and JNK knockdown suppress the lymphatic metastasis potential of hepatocellular carcinoma cells: Possible contributions of ATF2 and sequence-related lncRNA NONMMUT114121.1.
Deng Q, Wang H, Pan Z, Jin Y
Translational cancer research 2021 Mar;10(3):1410-1419
Translational cancer research 2021 Mar;10(3):1410-1419
Plumbagin, a Biomolecule with (Anti)Osteoclastic Properties.
Sultanli S, Ghumnani S, Ashma R, Kubatzky KF
International journal of molecular sciences 2021 Mar 9;22(5)
International journal of molecular sciences 2021 Mar 9;22(5)
Identification of Overexpressed Genes in Malignant Pleural Mesothelioma.
Morani F, Bisceglia L, Rosini G, Mutti L, Melaiu O, Landi S, Gemignani F
International journal of molecular sciences 2021 Mar 8;22(5)
International journal of molecular sciences 2021 Mar 8;22(5)
Epigenetically modulated miR-1224 suppresses the proliferation of HCC through CREB-mediated activation of YAP signaling pathway.
Yang S, Jiang W, Yang W, Yang C, Yang X, Chen K, Hu Y, Shen G, Lu L, Cheng F, Zhang F, Rao J, Wang X
Molecular therapy. Nucleic acids 2021 Mar 5;23:944-958
Molecular therapy. Nucleic acids 2021 Mar 5;23:944-958
Circular RNA RBPMS inhibits bladder cancer progression via miR-330-3p/RAI2 regulation.
Yang C, Mou Z, Zhang Z, Wu S, Zhou Q, Chen Y, Gong J, Xu C, Ou Y, Chen X, Dai X, Jiang H
Molecular therapy. Nucleic acids 2021 Mar 5;23:872-886
Molecular therapy. Nucleic acids 2021 Mar 5;23:872-886
Long noncoding RNA SMUL suppresses SMURF2 production-mediated muscle atrophy via nonsense-mediated mRNA decay.
Cai B, Li Z, Ma M, Zhang J, Kong S, Abdalla BA, Xu H, Jebessa E, Zhang X, Lawal RA, Nie Q
Molecular therapy. Nucleic acids 2021 Mar 5;23:512-526
Molecular therapy. Nucleic acids 2021 Mar 5;23:512-526
Design, synthesis and pharmacological evaluation of bicyclic and tetracyclic pyridopyrimidinone analogues as new KRAS(G12C) inhibitors.
Xiao X, Lai M, Song Z, Geng M, Ding J, Xie H, Zhang A
European journal of medicinal chemistry 2021 Mar 5;213:113082
European journal of medicinal chemistry 2021 Mar 5;213:113082
miR-98-5p protects against cerebral ischemia/reperfusion injury through anti-apoptosis and anti-oxidative stress in mice.
Yu S, Zhai J, Yu J, Yang Q, Yang J
Journal of biochemistry 2021 Mar 5;169(2):195-206
Journal of biochemistry 2021 Mar 5;169(2):195-206
Hepatic HuR protects against the pathogenesis of non-alcoholic fatty liver disease by targeting PTEN.
Tian M, Wang J, Liu S, Li X, Li J, Yang J, Zhang C, Zhang W
Cell death & disease 2021 Mar 4;12(3):236
Cell death & disease 2021 Mar 4;12(3):236
HIF-1/AKT Signaling-Activated PFKFB2 Alleviates Cardiac Dysfunction and Cardiomyocyte Apoptosis in Response to Hypoxia.
Gao J, Feng W, Lv W, Liu W, Fu C
International heart journal 2021 Mar 30;62(2):350-358
International heart journal 2021 Mar 30;62(2):350-358
Involvement of HECTD1 in LPS-induced astrocyte activation via σ-1R-JNK/p38-FOXJ2 axis.
Tang Y, Zhou M, Huang R, Shen L, Yang L, Zhou Z, Ren H, Bai Y
Cell & bioscience 2021 Mar 30;11(1):62
Cell & bioscience 2021 Mar 30;11(1):62
LMNB2 promotes the progression of colorectal cancer by silencing p21 expression.
Dong CH, Jiang T, Yin H, Song H, Zhang Y, Geng H, Shi PC, Xu YX, Gao H, Liu LY, Zhou L, Zhang ZH, Song J
Cell death & disease 2021 Mar 29;12(4):331
Cell death & disease 2021 Mar 29;12(4):331
Let-7i-5p enhances cell proliferation, migration and invasion of ccRCC by targeting HABP4.
Liu Y, Hu X, Hu L, Xu C, Liang X
BMC urology 2021 Mar 28;21(1):49
BMC urology 2021 Mar 28;21(1):49
Parkinson's Disease Causative Mutation in Vps35 Disturbs Tetherin Trafficking to Cell Surfaces and Facilitates Virus Spread.
Ding Y, Li Y, Chhetri G, Peng X, Wu J, Wang Z, Zhao B, Zhao W, Li X
Cells 2021 Mar 28;10(4)
Cells 2021 Mar 28;10(4)
Glutathione S-transferase Pi (Gstp) proteins regulate neuritogenesis in the developing cerebral cortex.
Liu X, Blazejewski SM, Bennison SA, Toyo-Oka K
Human molecular genetics 2021 Mar 25;30(1):30-45
Human molecular genetics 2021 Mar 25;30(1):30-45
Metabolomics analysis delineates the therapeutic effects of Huangqi decoction and astragalosides on α-naphthylisothiocyanate (ANIT) -induced cholestasis in rats.
Qiu J, Yan J, Liu W, Liu X, Lin J, Du Z, Qi L, Liu J, Xie G, Liu P, Wang X
Journal of ethnopharmacology 2021 Mar 25;268:113658
Journal of ethnopharmacology 2021 Mar 25;268:113658
Crocetin ameliorates chronic restraint stress-induced depression-like behaviors in mice by regulating MEK/ERK pathways and gut microbiota.
Lin S, Li Q, Jiang S, Xu Z, Jiang Y, Liu L, Jiang J, Tong Y, Wang P
Journal of ethnopharmacology 2021 Mar 25;268:113608
Journal of ethnopharmacology 2021 Mar 25;268:113608
NMR-Based Metabolomic Analysis for the Effects of α-Ketoglutarate Supplementation on C2C12 Myoblasts in Different Energy States.
Li Y, Li X, Gao Y, Huang C, Lin D
Molecules (Basel, Switzerland) 2021 Mar 25;26(7)
Molecules (Basel, Switzerland) 2021 Mar 25;26(7)
Membrane-cytoplasm translocation of annexin A4 is involved in the metastasis of colorectal carcinoma.
Peng Y, Zhang Z, Zhang A, Liu C, Sun Y, Peng Z, Liu Y
Aging 2021 Mar 24;13(7):10312-10325
Aging 2021 Mar 24;13(7):10312-10325
Acoustic Droplet Vitrification Method for High-Efficiency Preservation of Rare Cells.
Xia Y, Huang LX, Chen H, Li J, Chen KK, Hu H, Wang FB, Ding Z, Guo SS
ACS applied materials & interfaces 2021 Mar 24;13(11):12950-12959
ACS applied materials & interfaces 2021 Mar 24;13(11):12950-12959
CircRNA RSF1 regulated ox-LDL induced vascular endothelial cells proliferation, apoptosis and inflammation through modulating miR-135b-5p/HDAC1 axis in atherosclerosis.
Zhang X, Lu J, Zhang Q, Luo Q, Liu B
Biological research 2021 Mar 23;54(1):11
Biological research 2021 Mar 23;54(1):11
Tanshinone IIA combined with CsA inhibit myocardial cell apoptosis induced by renal ischemia-reperfusion injury in obese rats.
Tai H, Jiang XL, Lan ZM, Li Y, Kong L, Yao SC, Song N, Lv MJ, Wu J, Yang P, Xiao XS, Yang GL, Kuang JS, Jia LQ
BMC complementary medicine and therapies 2021 Mar 22;21(1):100
BMC complementary medicine and therapies 2021 Mar 22;21(1):100
VPS34 regulates dynamin to determine the endocytosis of mitochondria-targeted zinc oxide nanoparticles in human osteosarcoma cells.
Pan X, He G, Hai B, Liu Y, Bian L, Yong L, Zhang H, Yang C, Du C, Mao T, Ma Y, Jia F, Dou X, Zhai S, Liu X
Journal of materials chemistry. B 2021 Mar 21;9(11):2641-2655
Journal of materials chemistry. B 2021 Mar 21;9(11):2641-2655
Identification of HOXA10 target genes in human endometrial stromal cells by RNA-seq analysis.
Wang Y, Hu S, Yao G, Sun Y
Acta biochimica et biophysica Sinica 2021 Mar 2;53(3):365-371
Acta biochimica et biophysica Sinica 2021 Mar 2;53(3):365-371
Clostridium Butyricum ZJU-F1 Benefits the Intestinal Barrier Function and Immune Response Associated with Its Modulation of Gut Microbiota in Weaned Piglets.
Fu J, Wang T, Xiao X, Cheng Y, Wang F, Jin M, Wang Y, Zong X
Cells 2021 Mar 2;10(3)
Cells 2021 Mar 2;10(3)
TagBiFC technique allows long-term single-molecule tracking of protein-protein interactions in living cells.
Shao S, Zhang H, Zeng Y, Li Y, Sun C, Sun Y
Communications biology 2021 Mar 19;4(1):378
Communications biology 2021 Mar 19;4(1):378
HDAC11 inhibition disrupts porcine oocyte meiosis via regulating α-tubulin acetylation and histone modifications.
Huang R, Sui L, Fu C, Zhai Y, Dai X, Zhang S, Li Z
Aging 2021 Mar 19;13(6):8849-8864
Aging 2021 Mar 19;13(6):8849-8864
CircSPI1 acts as an oncogene in acute myeloid leukemia through antagonizing SPI1 and interacting with microRNAs.
Wang X, Jin P, Zhang Y, Wang K
Cell death & disease 2021 Mar 19;12(4):297
Cell death & disease 2021 Mar 19;12(4):297
The MEK1/2 Pathway as a Therapeutic Target in High-Grade Serous Ovarian Carcinoma.
Chesnokov MS, Khan I, Park Y, Ezell J, Mehta G, Yousif A, Hong LJ, Buckanovich RJ, Takahashi A, Chefetz I
Cancers 2021 Mar 18;13(6)
Cancers 2021 Mar 18;13(6)
E3 Ubiquitin Ligase ASB17 Promotes Apoptosis by Ubiquitylating and Degrading BCLW and MCL1.
Yang G, Wan P, Xiang Q, Huang S, Huang S, Wang J, Wu K, Wu J
Biology 2021 Mar 18;10(3)
Biology 2021 Mar 18;10(3)
Kaempferol Reverses Aerobic Glycolysis via miR-339-5p-Mediated PKM Alternative Splicing in Colon Cancer Cells.
Wu H, Cui M, Li C, Li H, Dai Y, Cui K, Li Z
Journal of agricultural and food chemistry 2021 Mar 17;69(10):3060-3068
Journal of agricultural and food chemistry 2021 Mar 17;69(10):3060-3068
TMEM119 facilitates ovarian cancer cell proliferation, invasion, and migration via the PDGFRB/PI3K/AKT signaling pathway.
Sun T, Bi F, Liu Z, Yang Q
Journal of translational medicine 2021 Mar 17;19(1):111
Journal of translational medicine 2021 Mar 17;19(1):111
Rab26 suppresses migration and invasion of breast cancer cells through mediating autophagic degradation of phosphorylated Src.
Liu H, Zhou Y, Qiu H, Zhuang R, Han Y, Liu X, Qiu X, Wang Z, Xu L, Tan R, Hong W, Wang T
Cell death & disease 2021 Mar 17;12(4):284
Cell death & disease 2021 Mar 17;12(4):284
Astrocytic ApoE reprograms neuronal cholesterol metabolism and histone-acetylation-mediated memory.
Li X, Zhang J, Li D, He C, He K, Xue T, Wan L, Zhang C, Liu Q
Neuron 2021 Mar 17;109(6):957-970.e8
Neuron 2021 Mar 17;109(6):957-970.e8
TBC1D16 predicts chemosensitivity and prognosis in adult acute myeloid leukemia (AML) patients.
Liu H, Chen P, Yang YL, Zhu KW, Wang T, Tang L, Liu YL, Cao S, Zhou G, Zeng H, Zhao XL, Zhang W, Chen XP
European journal of pharmacology 2021 Mar 15;895:173894
European journal of pharmacology 2021 Mar 15;895:173894
GR/NF-κB signaling pathway regulates hippocampal inflammatory responses in diabetic rats with chronic unpredictable mild stress.
Li ZR, Han YS, Liu Z, Zhao HQ, Liu J, Yang H, Wang YH
European journal of pharmacology 2021 Mar 15;895:173861
European journal of pharmacology 2021 Mar 15;895:173861
PDX models reflect the proteome landscape of pediatric acute lymphoblastic leukemia but divert in select pathways.
Uzozie AC, Ergin EK, Rolf N, Tsui J, Lorentzian A, Weng SSH, Nierves L, Smith TG, Lim CJ, Maxwell CA, Reid GSD, Lange PF
Journal of experimental & clinical cancer research : CR 2021 Mar 15;40(1):96
Journal of experimental & clinical cancer research : CR 2021 Mar 15;40(1):96
Thrombin inhibitor argatroban modulates bone marrow stromal cells behaviors and promotes osteogenesis through canonical Wnt signaling.
Song J, Jiang N, Gan X, Zhi W, Zhu Z
Life sciences 2021 Mar 15;269:119073
Life sciences 2021 Mar 15;269:119073
Identification and functional analysis of senescence-associated secretory phenotype of premature senescent hepatocytes induced by hexavalent chromium.
Ma Y, Liang Y, Liang N, Zhang Y, Xiao F
Ecotoxicology and environmental safety 2021 Mar 15;211:111908
Ecotoxicology and environmental safety 2021 Mar 15;211:111908
The role of Se content in improving anti-tumor activities and its potential mechanism for selenized Artemisia sphaerocephala polysaccharides.
Liu S, Hu J, Li M, Zhu S, Guo S, Guo H, Wang T, Zhang Y, Zhang J, Wang J
Food & function 2021 Mar 15;12(5):2058-2074
Food & function 2021 Mar 15;12(5):2058-2074
MiR-1290 promotes myoblast differentiation and protects against myotube atrophy via Akt/p70/FoxO3 pathway regulation.
Che J, Xu C, Wu Y, Jia P, Han Q, Ma Y, Wang X, Zheng Y
Skeletal muscle 2021 Mar 15;11(1):6
Skeletal muscle 2021 Mar 15;11(1):6
Perilipin 5 ameliorates high-glucose-induced podocyte injury via Akt/GSK-3β/Nrf2-mediated suppression of apoptosis, oxidative stress, and inflammation.
Feng J, Xie L, Yu X, Liu C, Dong H, Lu W, Kong R
Biochemical and biophysical research communications 2021 Mar 12;544:22-30
Biochemical and biophysical research communications 2021 Mar 12;544:22-30
Citrus Alkaline Extracts Inhibit Senescence of A549 Cells to Alleviate Pulmonary Fibrosis via the β-Catenin/P53 Pathway.
Han D, Xu Y, Peng WP, Feng F, Wang Z, Gu C, Zhou X
Medical science monitor : international medical journal of experimental and clinical research 2021 Mar 12;27:e928547
Medical science monitor : international medical journal of experimental and clinical research 2021 Mar 12;27:e928547
Synergistic effects of AAGL and anti-PD-1 on hepatocellular carcinoma through lymphocyte recruitment to the liver.
Ye X, Wang X, Yu W, Yang Q, Li Y, Jin Y, Su Y, Song J, Xu B, Sun H
Cancer biology & medicine 2021 Mar 12;18(4):1092-108
Cancer biology & medicine 2021 Mar 12;18(4):1092-108
Lnc13728 facilitates human mesenchymal stem cell adipogenic differentiation via positive regulation of ZBED3 and downregulation of the WNT/β-catenin pathway.
Xu H, Yang Y, Fan L, Deng L, Fan J, Li D, Li H, Zhao RC
Stem cell research & therapy 2021 Mar 12;12(1):176
Stem cell research & therapy 2021 Mar 12;12(1):176
Novel IMB16-4 Compound Loaded into Silica Nanoparticles Exhibits Enhanced Oral Bioavailability and Increased Anti-Liver Fibrosis In Vitro.
Niu X, Wang X, Niu B, Li G, Yang X, Wang Y, Li G
Molecules (Basel, Switzerland) 2021 Mar 11;26(6)
Molecules (Basel, Switzerland) 2021 Mar 11;26(6)
SRP54 mutations induce congenital neutropenia via dominant-negative effects on XBP1 splicing.
Schürch C, Schaefer T, Müller JS, Hanns P, Arnone M, Dumlin A, Schärer J, Sinning I, Wild K, Skokowa J, Welte K, Carapito R, Bahram S, Konantz M, Lengerke C
Blood 2021 Mar 11;137(10):1340-1352
Blood 2021 Mar 11;137(10):1340-1352
Isoliquiritigenin Reverses Epithelial-Mesenchymal Transition Through Modulation of the TGF-β/Smad Signaling Pathway in Endometrial Cancer.
Chen HY, Chiang YF, Huang JS, Huang TC, Shih YH, Wang KL, Ali M, Hong YH, Shieh TM, Hsia SM
Cancers 2021 Mar 11;13(6)
Cancers 2021 Mar 11;13(6)
MAGI1 inhibits the AMOTL2/p38 stress pathway and prevents luminal breast tumorigenesis.
Kantar D, Mur EB, Mancini M, Slaninova V, Salah YB, Costa L, Forest E, Lassus P, Géminard C, Boissière-Michot F, Orsetti B, Theillet C, Colinge J, Benistant C, Maraver A, Heron-Milhavet L, Djiane A
Scientific reports 2021 Mar 11;11(1):5752
Scientific reports 2021 Mar 11;11(1):5752
The role of irreversible electroporation in promoting M1 macrophage polarization via regulating the HMGB1-RAGE-MAPK axis in pancreatic cancer.
He C, Sun S, Zhang Y, Xie F, Li S
Oncoimmunology 2021 Mar 11;10(1):1897295
Oncoimmunology 2021 Mar 11;10(1):1897295
Positive regulation of Type III secretion effectors and virulence by RyhB paralogs in Salmonella enterica serovar Enteritidis.
Chen B, Meng X, Ni J, He M, Chen Y, Xia P, Wang H, Liu S, Zhu G, Meng X
Veterinary research 2021 Mar 10;52(1):44
Veterinary research 2021 Mar 10;52(1):44
Downregulation of lncRNA ZNF582-AS1 due to DNA hypermethylation promotes clear cell renal cell carcinoma growth and metastasis by regulating the N(6)-methyladenosine modification of MT-RNR1.
Yang W, Zhang K, Li L, Xu Y, Ma K, Xie H, Zhou J, Cai L, Gong Y, Gong K
Journal of experimental & clinical cancer research : CR 2021 Mar 10;40(1):92
Journal of experimental & clinical cancer research : CR 2021 Mar 10;40(1):92
Endogenous conversion of n-6 to n-3 polyunsaturated fatty acids facilitates the repair of cardiotoxin-induced skeletal muscle injury in fat-1 mice.
Wang ZG, Zhu ZQ, He ZY, Cheng P, Liang S, Chen AM, Yang Q
Aging 2021 Mar 10;13(6):8454-8466
Aging 2021 Mar 10;13(6):8454-8466
A novel function of African Swine Fever Virus pE66L in inhibition of host translation by the PKR/eIF2α pathway.
Shen Z, Chen C, Yang Y, Xie Z, Ao Q, Lv L, Zhang S, Chen H, Hu R, Chen H, Peng G
Journal of virology 2021 Mar 1;95(5)
Journal of virology 2021 Mar 1;95(5)
Long Noncoding RNA DUXAP8 Promotes Pancreatic Carcinoma Cell Migration and Invasion Via Pathway by miR-448/WTAP/Fak Signaling Axis.
Li JR, Liu L, Luo H, Chen ZG, Wang JH, Li NF
Pancreas 2021 Mar 1;50(3):317-326
Pancreas 2021 Mar 1;50(3):317-326
TMEM2 binds to CSNK2A3 to inhibit HBV infection via activation of the JAK/STAT pathway.
Zhou H, Jia X, Hu K, Mo Z, Xu W, Peng L, Wang K, Zhu X
Experimental cell research 2021 Mar 1;400(1):112517
Experimental cell research 2021 Mar 1;400(1):112517
Cancer-associated fibroblasts promote the survival of irradiated nasopharyngeal carcinoma cells via the NF-κB pathway.
Huang W, Zhang L, Yang M, Wu X, Wang X, Huang W, Yuan L, Pan H, Wang Y, Wang Z, Wu Y, Huang J, Liang H, Li S, Liao L, Liu L, Guan J
Journal of experimental & clinical cancer research : CR 2021 Mar 1;40(1):87
Journal of experimental & clinical cancer research : CR 2021 Mar 1;40(1):87
Prematurity blunts the insulin- and amino acid-induced stimulation of translation initiation and protein synthesis in skeletal muscle of neonatal pigs.
Rudar M, Naberhuis JK, Suryawan A, Nguyen HV, Stoll B, Style CC, Verla MA, Olutoye OO, Burrin DG, Fiorotto ML, Davis TA
American journal of physiology. Endocrinology and metabolism 2021 Mar 1;320(3):E551-E565
American journal of physiology. Endocrinology and metabolism 2021 Mar 1;320(3):E551-E565
Endoplasmic Reticulum Stress-Mediated p62 Downregulation Inhibits Apoptosis via c-Jun Upregulation.
Yu W, Wang B, Zhou L, Xu G
Biomolecules & therapeutics 2021 Mar 1;29(2):195-204
Biomolecules & therapeutics 2021 Mar 1;29(2):195-204
Contributions of HO-1-Dependent MAPK to Regulating Intestinal Barrier Disruption.
Zhang Z, Zhang Q, Li F, Xin Y, Duan Z
Biomolecules & therapeutics 2021 Mar 1;29(2):175-183
Biomolecules & therapeutics 2021 Mar 1;29(2):175-183
Cadmium and molybdenum co-induce pyroptosis via ROS/PTEN/PI3K/AKT axis in duck renal tubular epithelial cells.
Zhang C, Lin T, Nie G, Hu R, Pi S, Wei Z, Wang C, Xing C, Hu G
Environmental pollution (Barking, Essex : 1987) 2021 Mar 1;272:116403
Environmental pollution (Barking, Essex : 1987) 2021 Mar 1;272:116403
Tubeimoside I promotes angiogenesis via activation of eNOS-VEGF signaling pathway.
Yang X, Li X, Luo M, Guo Y, Li C, Lv D, Cheng Z, Huang L, Shang FF, Huang B, Shen J, Luo S, Yan J
Journal of ethnopharmacology 2021 Mar 1;267:113642
Journal of ethnopharmacology 2021 Mar 1;267:113642
Benzo[a]pyrene induces fibrotic changes and impairs differentiation in lung stem cells.
Tseng YH, Chen YC, Yu AL, Yu J
Ecotoxicology and environmental safety 2021 Mar 1;210:111892
Ecotoxicology and environmental safety 2021 Mar 1;210:111892
Circulating Exosomes From Patients With Graves' Disease Induce an Inflammatory Immune Response.
Cui X, Huang M, Wang S, Zhao N, Huang T, Wang Z, Qiao J, Wang S, Shan Z, Teng W, Li Y
Endocrinology 2021 Mar 1;162(3)
Endocrinology 2021 Mar 1;162(3)
METTL3-mediated m(6)A modification regulates cell cycle progression of dental pulp stem cells.
Luo H, Liu W, Zhang Y, Yang Y, Jiang X, Wu S, Shao L
Stem cell research & therapy 2021 Mar 1;12(1):159
Stem cell research & therapy 2021 Mar 1;12(1):159
CRISPR/Cas9-mediated knockin of human factor IX into swine factor IX locus effectively alleviates bleeding in hemophilia B pigs.
Chen J, An B, Yu B, Peng X, Yuan H, Yang Q, Chen X, Yu T, Wang L, Zhang X, Wang H, Zou X, Pang D, Ouyang H, Tang X
Haematologica 2021 Mar 1;106(3):829-837
Haematologica 2021 Mar 1;106(3):829-837
Iguratimod-encapsulating PLGA-NPs induce human multiple myeloma cell death via reactive oxygen species and Caspase-dependent signalling.
Wang F, Younis M, Luo Y, Zhang L, Yuan L
International immunopharmacology 2021 Jun;95:107532
International immunopharmacology 2021 Jun;95:107532
Tumor protein D52 promotes breast cancer proliferation and migration via the long non-coding RNA NEAT1/microRNA-218-5p axis.
Ren J, Chen Y, Kong W, Li Y, Lu F
Annals of translational medicine 2021 Jun;9(12):1008
Annals of translational medicine 2021 Jun;9(12):1008
Overexpression of lipoic acid synthase gene alleviates diabetic nephropathy of Lepr(db/db) mice.
Zhao Y, Yan T, Xiong C, Chang M, Gao Q, Yao S, Wu W, Yi X, Xu G
BMJ open diabetes research & care 2021 Jun;9(1)
BMJ open diabetes research & care 2021 Jun;9(1)
Vitexin exerts protective effects against calcium oxalate crystal-induced kidney pyroptosis in vivo and in vitro.
Ding T, Zhao T, Li Y, Liu Z, Ding J, Ji B, Wang Y, Guo Z
Phytomedicine : international journal of phytotherapy and phytopharmacology 2021 Jun;86:153562
Phytomedicine : international journal of phytotherapy and phytopharmacology 2021 Jun;86:153562
PFKP facilitates ATG4B phosphorylation during amino acid deprivation-induced autophagy.
Li X, Sun L, Yan G, Yan X
Cellular signalling 2021 Jun;82:109956
Cellular signalling 2021 Jun;82:109956
Suberoylanilide Hydroxamic Acid (SAHA) Reduces Fibrosis Markers and Deactivates Human Stellate Cells via the Epithelial-Mesenchymal Transition (EMT).
Özel M, Baskol M, Akalın H, Baskol G
Cell biochemistry and biophysics 2021 Jun;79(2):349-357
Cell biochemistry and biophysics 2021 Jun;79(2):349-357
Human SND2 mediates ER targeting of GPI-anchored proteins with low hydrophobic GPI attachment signals.
Yang J, Hirata T, Liu YS, Guo XY, Gao XD, Kinoshita T, Fujita M
FEBS letters 2021 Jun;595(11):1542-1558
FEBS letters 2021 Jun;595(11):1542-1558
A phase-separated nuclear GBPL circuit controls immunity in plants.
Huang S, Zhu S, Kumar P, MacMicking JD
Nature 2021 Jun;594(7863):424-429
Nature 2021 Jun;594(7863):424-429
Carbon monoxide alleviates senescence in diabetic nephropathy by improving autophagy.
Chen L, Mei G, Jiang C, Cheng X, Li D, Zhao Y, Chen H, Wan C, Yao P, Gao C, Tang Y
Cell proliferation 2021 Jun;54(6):e13052
Cell proliferation 2021 Jun;54(6):e13052
Attenuation of the upregulation of NF‑κB and AP‑1 DNA‑binding activities induced by tunicamycin or hypoxia/reoxygenation in neonatal rat cardiomyocytes by SERCA2a overexpression.
Qu Z, Lu X, Qu Y, Tao T, Liu X, Li X
International journal of molecular medicine 2021 Jun;47(6)
International journal of molecular medicine 2021 Jun;47(6)
Long non‑coding RNA MIR4435‑2HG promotes the progression of head and neck squamous cell carcinoma by regulating the miR‑383‑5p/RBM3 axis.
Wang S, Chen X, Qiao T
Oncology reports 2021 Jun;45(6)
Oncology reports 2021 Jun;45(6)
[Retracted] Hypoxia‑induced mitochondrial translocation of DNM1L increases mitochondrial fission and triggers mPTP opening in HCC cells via activation of HK2.
Cai M, He P, Fang DL
Oncology reports 2021 Jun;45(6)
Oncology reports 2021 Jun;45(6)
Drug-repositioning screening identified fludarabine and risedronic acid as potential therapeutic compounds for malignant pleural mesothelioma.
Dell'Anno I, Martin SA, Barbarino M, Melani A, Silvestri R, Bottaro M, Paolicchi E, Corrado A, Cipollini M, Melaiu O, Giordano A, Luzzi L, Gemignani F, Landi S
Investigational new drugs 2021 Jun;39(3):644-657
Investigational new drugs 2021 Jun;39(3):644-657
Generation of A Stable GFP-reporter Zika Virus System for High-throughput Screening of Zika Virus Inhibitors.
Zhang JW, Wang H, Liu J, Ma L, Hua RH, Bu ZG
Virologica Sinica 2021 Jun;36(3):476-489
Virologica Sinica 2021 Jun;36(3):476-489
Differentially expressed proteins identified by TMT proteomics analysis in children with verrucous epidermal naevi.
Yuan T, Cai ML, Sheng YM, Ding X, Shen TT, Li WR, Huang H, Liang B, Zhang XJ, Zhu QX
Journal of the European Academy of Dermatology and Venereology : JEADV 2021 Jun;35(6):1393-1406
Journal of the European Academy of Dermatology and Venereology : JEADV 2021 Jun;35(6):1393-1406
Mutual dependency between lncRNA LETN and protein NPM1 in controlling the nucleolar structure and functions sustaining cell proliferation.
Wang X, Hu X, Song W, Xu H, Xiao Z, Huang R, Bai Q, Zhang F, Chen Y, Liu Y, Fang J, Li X, Shen Q, Zhao H, Yang X
Cell research 2021 Jun;31(6):664-683
Cell research 2021 Jun;31(6):664-683
Generation and identification of endothelial-specific Hrh2 knockout mice.
Meng R, Cai WK, Xu WM, Feng Q, Wang P, Huang YH, Fan YX, Zhou T, Yang Q, Li ZR, He GH
Transgenic research 2021 Jun;30(3):251-261
Transgenic research 2021 Jun;30(3):251-261
Comprehensive interactome analysis of the spike protein of swine acute diarrhea syndrome coronavirus.
Wang Q, Luo Y, Shang W, Shi Z, Xiao G, Zhang L
Biosafety and health 2021 Jun;3(3):156-163
Biosafety and health 2021 Jun;3(3):156-163
Targeting IDH1/2 mutant cancers with combinations of ATR and PARP inhibitors.
Sule A, Van Doorn J, Sundaram RK, Ganesa S, Vasquez JC, Bindra RS
NAR cancer 2021 Jun;3(2):zcab018
NAR cancer 2021 Jun;3(2):zcab018
Matrix stiffness-mediated effects on macrophages polarization and their LOXL2 expression.
Xing X, Wang Y, Zhang X, Gao X, Li M, Wu S, Zhao Y, Chen J, Gao D, Chen R, Ren Z, Zhang K, Cui J
The FEBS journal 2021 Jun;288(11):3465-3477
The FEBS journal 2021 Jun;288(11):3465-3477
Lipotoxicity suppresses the synthesis of growth hormone in pituitary somatotrophs via endoplasmic reticulum stress.
Gong Y, Yang J, Wei S, Yang R, Gao L, Shao S, Zhao J
Journal of cellular and molecular medicine 2021 Jun;25(11):5250-5259
Journal of cellular and molecular medicine 2021 Jun;25(11):5250-5259
Rescue of maternal immune activation-induced behavioral abnormalities in adult mouse offspring by pathogen-activated maternal T(reg) cells.
Xu Z, Zhang X, Chang H, Kong Y, Ni Y, Liu R, Zhang X, Hu Y, Yang Z, Hou M, Mao R, Liu WT, Du Y, Yu S, Wang Z, Ji M, Zhou Z
Nature neuroscience 2021 Jun;24(6):818-830
Nature neuroscience 2021 Jun;24(6):818-830
Crosstalk between the COX2-PGE2-EP4 signaling pathway and primary cilia in osteoblasts after mechanical stimulation.
Li YH, Zhu D, Yang T, Cheng L, Sun J, Tan L
Journal of cellular physiology 2021 Jun;236(6):4764-4777
Journal of cellular physiology 2021 Jun;236(6):4764-4777
Acvr1 deletion in osteoblasts impaired mandibular bone mass through compromised osteoblast differentiation and enhanced sRANKL-induced osteoclastogenesis.
Hu Y, Hao X, Liu C, Ren C, Wang S, Yan G, Meng Y, Mishina Y, Shi C, Sun H
Journal of cellular physiology 2021 Jun;236(6):4580-4591
Journal of cellular physiology 2021 Jun;236(6):4580-4591
SOD3 deficiency induces liver fibrosis by promoting hepatic stellate cell activation and epithelial-mesenchymal transition.
Sun YL, Bai T, Zhou L, Zhu RT, Wang WJ, Liang RP, Li J, Zhang CX, Gou JJ
Journal of cellular physiology 2021 Jun;236(6):4313-4329
Journal of cellular physiology 2021 Jun;236(6):4313-4329
Dioscin inhibits SCC15 cell proliferation via the RASSF1A/MST2/YAP axis.
Tian H, Chen X, Zhang Y, Wang Y, Fu X, Gu W, Wen Y
Molecular medicine reports 2021 Jun;23(6)
Molecular medicine reports 2021 Jun;23(6)
SEC61G is upregulated and required for tumor progression in human kidney cancer.
Meng H, Jiang X, Wang J, Sang Z, Guo L, Yin G, Wang Y
Molecular medicine reports 2021 Jun;23(6)
Molecular medicine reports 2021 Jun;23(6)
Salidroside overcomes dexamethasone resistance in T-acute lymphoblastic leukemia cells.
Niu YN, Zeng Y, Zhong FF, Long SL, Ren DW, Qin X, Liu WJ
Experimental and therapeutic medicine 2021 Jun;21(6):636
Experimental and therapeutic medicine 2021 Jun;21(6):636
Ginkgo biloba delays light-induced photoreceptor degeneration through antioxidant and antiapoptotic properties.
Chudhary M, Zhang C, Song S, Ren X, Kong L
Experimental and therapeutic medicine 2021 Jun;21(6):576
Experimental and therapeutic medicine 2021 Jun;21(6):576
Oncogenic WIP1 phosphatase attenuates the DNA damage response and sensitizes p53 mutant Jurkat cells to apoptosis.
Eren MK, Kartal NB, Pilevneli H
Oncology letters 2021 Jun;21(6):479
Oncology letters 2021 Jun;21(6):479
PHD Finger Protein 19 Promotes Cardiac Hypertrophy via Epigenetically Regulating SIRT2.
Gu W, Cheng Y, Wang S, Sun T, Li Z
Cardiovascular toxicology 2021 Jun;21(6):451-461
Cardiovascular toxicology 2021 Jun;21(6):451-461
DEK is highly expressed in breast cancer and is associated with malignant phenotype and progression.
Yang MQ, Bai LL, Wang Z, Lei L, Zheng YW, Li ZH, Huang WJ, Liu CC, Xu HT
Oncology letters 2021 Jun;21(6):440
Oncology letters 2021 Jun;21(6):440
Long noncoding RNA PM maintains cerebellar synaptic integrity and Cbln1 activation via Pax6/Mll1-mediated H3K4me3.
Jin Y, Zhang B, Lu J, Song Y, Wang W, Zhang W, Shao F, Gong M, Wang M, Liang X, Li S, Zhang Z, Shan G, Wang X
PLoS biology 2021 Jun;19(6):e3001297
PLoS biology 2021 Jun;19(6):e3001297
Ketoplatin in triple-negative breast cancer cells MDA-MB-231: High efficacy and low toxicity, and positive impact on inflammatory microenvironment.
Ma ZY, Song XQ, Hu JJ, Wang DB, Ding XJ, Liu RP, Dai ML, Meng FY, Xu JY
Biochemical pharmacology 2021 Jun;188:114523
Biochemical pharmacology 2021 Jun;188:114523
Virus-inducible IGFALS facilitates innate immune responses by mediating IRAK1 and TRAF6 activation.
Xu G, Deng F, Zuo Q, Liu L, Dou K, Cheng Z, Cao W, Luo C, Yu C, Liu S, Zhu Y
Cellular & molecular immunology 2021 Jun;18(6):1587-1589
Cellular & molecular immunology 2021 Jun;18(6):1587-1589
T-17, a spirostanol saponin, inhibits p53-independent proliferation and p53-dependent migration of gastric cancer cells.
Xu J, Wang Y, Wang Z, Wang Y, He X
Steroids 2021 Jun;170:108828
Steroids 2021 Jun;170:108828
SNX-3 mediates retromer-independent tubular endosomal recycling by opposing EEA-1-facilitated trafficking.
Tian Y, Kang Q, Shi X, Wang Y, Zhang N, Ye H, Xu Q, Xu T, Zhang R
PLoS genetics 2021 Jun;17(6):e1009607
PLoS genetics 2021 Jun;17(6):e1009607
NIR-II Absorbing Semiconducting Polymer-Triggered Gene-Directed Enzyme Prodrug Therapy for Cancer Treatment.
Zhang X, Yang Y, Kang T, Wang J, Yang G, Yang Y, Lin X, Wang L, Li K, Liu J, Ni JS
Small (Weinheim an der Bergstrasse, Germany) 2021 Jun;17(23):e2100501
Small (Weinheim an der Bergstrasse, Germany) 2021 Jun;17(23):e2100501
PPARα agonist WY-14,643 enhances ethanol metabolism in mice: Role of catalase.
Chen X, Xu Y, Denning KL, Grigore A, Lu Y
Free radical biology & medicine 2021 Jun;169:283-293
Free radical biology & medicine 2021 Jun;169:283-293
Paricalcitol inhibits oxidative stress-induced cell senescence of the bile duct epithelium dependent on modulating Sirt1 pathway in cholestatic mice.
Jia R, Yang F, Yan P, Ma L, Yang L, Li L
Free radical biology & medicine 2021 Jun;169:158-168
Free radical biology & medicine 2021 Jun;169:158-168
Unbiased proteomic screening identifies a novel role for the E3 ubiquitin ligase Nedd4-2 in translational suppression during ER stress.
Eagleman DE, Zhu J, Liu DC, Seimetz J, Kalsotra A, Tsai NP
Journal of neurochemistry 2021 Jun;157(6):1809-1820
Journal of neurochemistry 2021 Jun;157(6):1809-1820
ALS-causing SOD1 mutants regulate occludin phosphorylation/ubiquitination and endocytic trafficking via the ITCH/Eps15/Rab5 axis.
Tang J, Kang Y, Zhou Y, Li X, Lan J, Wu L, Feng X, Peng Y
Neurobiology of disease 2021 Jun;153:105315
Neurobiology of disease 2021 Jun;153:105315
Prohibitin regulates mTOR pathway via interaction with FKBP8.
Zhang J, Yin Y, Wang J, Zhang J, Liu H, Feng W, Yang W, Zetter B, Xu Y
Frontiers of medicine 2021 Jun;15(3):448-459
Frontiers of medicine 2021 Jun;15(3):448-459
AMD3465 (hexahydrobromide) rescues the MG63 osteoblasts against the apoptosis induced by high glucose.
Zhang Z, Wu H, Huang S, Chen L, Chen X, Zhang W, Liao L, Zhang X
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Jun;138:111476
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Jun;138:111476
Gu-Ben-Fang-Xiao decoction modulates lipid metabolism by activating the AMPK pathway in asthma remission.
You YN, Xing QQ, Zhao X, Ji JJ, Yan H, Zhou T, Dong YM, Ren LS, Hou ST, Ding YY
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Jun;138:111403
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Jun;138:111403
Nuclear m(6)A reader YTHDC1 regulates the scaffold function of LINE1 RNA in mouse ESCs and early embryos.
Chen C, Liu W, Guo J, Liu Y, Liu X, Liu J, Dou X, Le R, Huang Y, Li C, Yang L, Kou X, Zhao Y, Wu Y, Chen J, Wang H, Shen B, Gao Y, Gao S
Protein & cell 2021 Jun;12(6):455-474
Protein & cell 2021 Jun;12(6):455-474
Design, synthesis and biological evaluation of anilide (dicarboxylic acid) shikonin esters as antitumor agents through targeting PI3K/Akt/mTOR signaling pathway.
Ma Y, Yang X, Han H, Wen Z, Yang M, Zhang Y, Fu J, Wang X, Yin T, Lu G, Qi J, Lin H, Wang X, Yang Y
Bioorganic chemistry 2021 Jun;111:104872
Bioorganic chemistry 2021 Jun;111:104872
C/EBPδ drives key endocrine signals in the human amnion at parturition.
Lu JW, Wang WS, Zhou Q, Ling LJ, Ying H, Sun Y, Myatt L, Sun K
Clinical and translational medicine 2021 Jun;11(6):e416
Clinical and translational medicine 2021 Jun;11(6):e416
HYD-PEP06 suppresses hepatocellular carcinoma metastasis, epithelial-mesenchymal transition and cancer stem cell-like properties by inhibiting PI3K/AKT and WNT/β-catenin signaling activation.
Tian W, Li J, Wang Z, Zhang T, Han Y, Liu Y, Chu W, Liu Y, Yang B
Acta pharmaceutica Sinica. B 2021 Jun;11(6):1592-1606
Acta pharmaceutica Sinica. B 2021 Jun;11(6):1592-1606
Metformin Carbon Dots for Promoting Periodontal Bone Regeneration via Activation of ERK/AMPK Pathway.
Ren C, Hao X, Wang L, Hu Y, Meng L, Zheng S, Ren F, Bu W, Wang H, Li D, Zhang K, Sun H
Advanced healthcare materials 2021 Jun;10(12):e2100196
Advanced healthcare materials 2021 Jun;10(12):e2100196
PARP inhibitors promote stromal fibroblast activation by enhancing CCL5 autocrine signaling in ovarian cancer.
Li X, Fang T, Xu S, Jin P, Zhou D, Wang Z, Li H, Yang Z, Chen G, Zheng X, Xia Y, Wei X, Zhang Z, Yang X, Wang Y, Gao Q
NPJ precision oncology 2021 Jun 9;5(1):49
NPJ precision oncology 2021 Jun 9;5(1):49
CircC16orf62 promotes hepatocellular carcinoma progression through the miR-138-5p/PTK2/AKT axis.
Zhang S, Lu Y, Jiang HY, Cheng ZM, Wei ZJ, Wei YH, Liu T, Xia BJ, Zhao XY, Huang Y, Zou X, Liu R, Zhou S
Cell death & disease 2021 Jun 9;12(6):597
Cell death & disease 2021 Jun 9;12(6):597
SARS-CoV-2 exacerbates proinflammatory responses in myeloid cells through C-type lectin receptors and Tweety family member 2.
Lu Q, Liu J, Zhao S, Gomez Castro MF, Laurent-Rolle M, Dong J, Ran X, Damani-Yokota P, Tang H, Karakousi T, Son J, Kaczmarek ME, Zhang Z, Yeung ST, McCune BT, Chen RE, Tang F, Ren X, Chen X, Hsu JCC, Teplova M, Huang B, Deng H, Long Z, Mudianto T, Jin S, Lin P, Du J, Zang R, Su TT, Herrera A, Zhou M, Yan R, Cui J, Zhu J, Zhou Q, Wang T, Ma J, Koralov SB, Zhang Z, Aifantis I, Segal LN, Diamond MS, Khanna KM, Stapleford KA, Cresswell P, Liu Y, Ding S, Xie Q, Wang J
Immunity 2021 Jun 8;54(6):1304-1319.e9
Immunity 2021 Jun 8;54(6):1304-1319.e9
SNP rs10420324 in the AMPA receptor auxiliary subunit TARP γ-8 regulates the susceptibility to antisocial personality disorder.
Peng SX, Wang YY, Zhang M, Zang YY, Wu D, Pei J, Li Y, Dai J, Guo X, Luo X, Zhang N, Yang JJ, Zhang C, Gao X, Liu N, Shi YS
Scientific reports 2021 Jun 7;11(1):11997
Scientific reports 2021 Jun 7;11(1):11997
Chronic exposure to PFO4DA and PFO5DoDA, two perfluoroalkyl ether carboxylic acids (PFECAs), suppresses hepatic stress signals and disturbs glucose and lipid metabolism in male mice.
Chen J, Li H, Yao J, Guo H, Zhang H, Guo Y, Sheng N, Wang J, Dai J
Journal of hazardous materials 2021 Jun 5;411:124963
Journal of hazardous materials 2021 Jun 5;411:124963
The functional characterization of phosphorylation of tristetraprolin at C-terminal NOT1-binding domain.
Hsieh HH, Chen YA, Chang YJ, Wang HH, Yu YH, Lin SW, Huang YJ, Lin S, Chang CJ
Journal of inflammation (London, England) 2021 Jun 5;18(1):22
Journal of inflammation (London, England) 2021 Jun 5;18(1):22
Design, synthesis, and neuroprotective effects of novel hybrid compounds containing edaravone analogue and 3-n-butylphthalide ring-opened derivatives.
Li X, Wang X, Miao L, Guo Y, Yuan R, Tian H
Biochemical and biophysical research communications 2021 Jun 4;556:99-105
Biochemical and biophysical research communications 2021 Jun 4;556:99-105
Protective effects of prucalopride in MPTP-induced Parkinson's disease mice: Neurochemistry, motor function and gut barrier.
Shi Y, Qiao CM, Zhou Y, Wu J, Cui C, Hong H, Jia XB, Huang SB, Yao L, Zhao WJ, Shen YQ
Biochemical and biophysical research communications 2021 Jun 4;556:16-22
Biochemical and biophysical research communications 2021 Jun 4;556:16-22
Matrine suppresses cell growth of diffuse large B-cell lymphoma via inhibiting CaMKIIγ/c-Myc/CDK6 signaling pathway.
Gu J, Wang X, Zhang L, Xiang J, Li J, Chen Z, Zhang Y, Chen J, Shen J
BMC complementary medicine and therapies 2021 Jun 4;21(1):163
BMC complementary medicine and therapies 2021 Jun 4;21(1):163
YTHDF1 promotes hepatocellular carcinoma progression via activating PI3K/AKT/mTOR signaling pathway and inducing epithelial-mesenchymal transition.
Luo X, Cao M, Gao F, He X
Experimental hematology & oncology 2021 Jun 4;10(1):35
Experimental hematology & oncology 2021 Jun 4;10(1):35
Formin-like protein 2 promotes cell proliferation by a p27-related mechanism in human breast cancer cells.
Jiao X, Wang B, Feng C, Song S, Tian B, Zhou C, Gao X, Sun W, Liu P
BMC cancer 2021 Jun 30;21(1):760
BMC cancer 2021 Jun 30;21(1):760
Self-stabilizing regulation of deubiquitinating enzymes in an enzymatic activity-dependent manner.
Hou Z, Shi W, Feng J, Wang W, Zheng E, Lin H, Yu C, Li L
International journal of biological macromolecules 2021 Jun 30;181:1081-1091
International journal of biological macromolecules 2021 Jun 30;181:1081-1091
The lipid-lowering drug fenofibrate combined with si-HOTAIR can effectively inhibit the proliferation of gliomas.
Zhu W, Zhao H, Xu F, Huang B, Dai X, Sun J, Nyalali AMK, Zhang K, Ni S
BMC cancer 2021 Jun 3;21(1):664
BMC cancer 2021 Jun 3;21(1):664
IL-37b alleviates endothelial cell apoptosis and inflammation in Kawasaki disease through IL-1R8 pathway.
Jia C, Zhuge Y, Zhang S, Ni C, Wang L, Wu R, Niu C, Wen Z, Rong X, Qiu H, Chu M
Cell death & disease 2021 Jun 3;12(6):575
Cell death & disease 2021 Jun 3;12(6):575
The CTNNBIP1-CLSTN1 fusion transcript regulates human neocortical development.
Ou MY, Xiao Q, Ju XC, Zeng PM, Huang J, Sheng AL, Luo ZG
Cell reports 2021 Jun 29;35(13):109290
Cell reports 2021 Jun 29;35(13):109290
HCP5, as the sponge of miR-1291, facilitates AML cell proliferation and restrains apoptosis via increasing PIK3R5 expression.
Liu Y, Jing XB, Wang ZC, Han QK
Human genomics 2021 Jun 29;15(1):38
Human genomics 2021 Jun 29;15(1):38
Trim21-mediated HIF-1α degradation attenuates aerobic glycolysis to inhibit renal cancer tumorigenesis and metastasis.
Chen X, Li Z, Yong H, Wang W, Wang D, Chu S, Li M, Hou P, Zheng J, Bai J
Cancer letters 2021 Jun 28;508:115-126
Cancer letters 2021 Jun 28;508:115-126
A network-based analysis and experimental validation of traditional Chinese medicine Yuanhu Zhitong Formula in treating neuropathic pain.
Liu T, Li T, Chen X, Zhang K, Li M, Yao W, Zhang C, Wan L
Journal of ethnopharmacology 2021 Jun 28;274:114037
Journal of ethnopharmacology 2021 Jun 28;274:114037
Ginsenoside Rh2 alleviates ulcerative colitis by regulating the STAT3/miR-214 signaling pathway.
Chen X, Xu T, Lv X, Zhang J, Liu S
Journal of ethnopharmacology 2021 Jun 28;274:113997
Journal of ethnopharmacology 2021 Jun 28;274:113997
Smek1 deficiency exacerbates experimental autoimmune encephalomyelitis by activating proinflammatory microglia and suppressing the IDO1-AhR pathway.
Duan RN, Yang CL, Du T, Liu A, Wang AR, Sun WJ, Li X, Li JX, Yan CZ, Liu QJ
Journal of neuroinflammation 2021 Jun 28;18(1):145
Journal of neuroinflammation 2021 Jun 28;18(1):145
The Anti-Tumor Effect and Underlying Apoptotic Mechanism of Ginsenoside Rk1 and Rg5 in Human Liver Cancer Cells.
Chen C, Lv Q, Li Y, Jin YH
Molecules (Basel, Switzerland) 2021 Jun 27;26(13)
Molecules (Basel, Switzerland) 2021 Jun 27;26(13)
An integrative transcriptome study reveals Ddit4/Redd1 as a key regulator of cancer cachexia in rodent models.
Niu M, Li L, Su Z, Wei L, Pu W, Zhao C, Ding Y, Wazir J, Cao W, Song S, Gao Q, Wang H
Cell death & disease 2021 Jun 26;12(7):652
Cell death & disease 2021 Jun 26;12(7):652
NOL4L, a novel nuclear protein, promotes cell proliferation and metastasis by enhancing the PI3K/AKT pathway in ovarian cancer.
Lin F, Zhou J, Li X, Wang X
Biochemical and biophysical research communications 2021 Jun 25;559:121-128
Biochemical and biophysical research communications 2021 Jun 25;559:121-128
Circ3823 contributes to growth, metastasis and angiogenesis of colorectal cancer: involvement of miR-30c-5p/TCF7 axis.
Guo Y, Guo Y, Chen C, Fan D, Wu X, Zhao L, Shao B, Sun Z, Ji Z
Molecular cancer 2021 Jun 25;20(1):93
Molecular cancer 2021 Jun 25;20(1):93
A knockout cell library of GPI biosynthetic genes for functional studies of GPI-anchored proteins.
Liu SS, Liu YS, Guo XY, Murakami Y, Yang G, Gao XD, Kinoshita T, Fujita M
Communications biology 2021 Jun 23;4(1):777
Communications biology 2021 Jun 23;4(1):777
Ferryl Hemoglobin and Heme Induce A(1)-Microglobulin in Hemorrhaged Atherosclerotic Lesions with Inhibitory Function against Hemoglobin and Lipid Oxidation.
Pethő D, Gáll T, Hendrik Z, Nagy A, Beke L, Gergely AP, Méhes G, Tóth C, Gram M, Åkerström B, Balla G, Balla J
International journal of molecular sciences 2021 Jun 22;22(13)
International journal of molecular sciences 2021 Jun 22;22(13)
Tissue- and stage-specific landscape of the mouse translatome.
Wang H, Wang Y, Yang J, Zhao Q, Tang N, Chen C, Li H, Cheng C, Xie M, Yang Y, Xie Z
Nucleic acids research 2021 Jun 21;49(11):6165-6180
Nucleic acids research 2021 Jun 21;49(11):6165-6180
m(6)A RNA hypermethylation-induced BACE2 boosts intracellular calcium release and accelerates tumorigenesis of ocular melanoma.
He F, Yu J, Yang J, Wang S, Zhuang A, Shi H, Gu X, Xu X, Chai P, Jia R
Molecular therapy : the journal of the American Society of Gene Therapy 2021 Jun 2;29(6):2121-2133
Molecular therapy : the journal of the American Society of Gene Therapy 2021 Jun 2;29(6):2121-2133
TROAP regulates cell cycle and promotes tumor progression through Wnt/β-Catenin signaling pathway in glioma cells.
Zhao ZQ, Wu XJ, Cheng YH, Zhou YF, Ma XM, Zhang J, Heng XY, Feng F
CNS neuroscience & therapeutics 2021 Jun 2;27(9):1064-76
CNS neuroscience & therapeutics 2021 Jun 2;27(9):1064-76
Mesenchymal stem cells ameliorate silica-induced pulmonary fibrosis by inhibition of inflammation and epithelial-mesenchymal transition.
Wei J, Zhao Q, Yang G, Huang R, Li C, Qi Y, Hao C, Yao W
Journal of cellular and molecular medicine 2021 Jun 2;25(13):6417-28
Journal of cellular and molecular medicine 2021 Jun 2;25(13):6417-28
Effects of WNT1 c.110 T>C and c.505G>T mutations on osteoblast differentiation via the WNT1/β-catenin signaling pathway.
Zhang B, Li R, Wang W, Zhou X, Luo B, Zhu Z, Zhang X, Ding A
Journal of orthopaedic surgery and research 2021 Jun 2;16(1):359
Journal of orthopaedic surgery and research 2021 Jun 2;16(1):359
A protocol for in vivo analysis of liver tumorigenesis in mice using sleeping beauty transposon system.
He L, Yu W, Lu Y, Zhang W, Xu J, Zhang L
STAR protocols 2021 Jun 18;2(2):100445
STAR protocols 2021 Jun 18;2(2):100445
Hypoxic postconditioning promotes mitophagy against transient global cerebral ischemia via PINK1/Parkin-induced mitochondrial ubiquitination in adult rats.
Wen H, Li L, Zhan L, Zuo Y, Li K, Qiu M, Li H, Sun W, Xu E
Cell death & disease 2021 Jun 18;12(7):630
Cell death & disease 2021 Jun 18;12(7):630
Long noncoding RNA AFAP1-AS1 promotes tumor progression and invasion by regulating the miR-2110/Sp1 axis in triple-negative breast cancer.
Zhang X, Li F, Zhou Y, Mao F, Lin Y, Shen S, Li Y, Zhang S, Sun Q
Cell death & disease 2021 Jun 18;12(7):627
Cell death & disease 2021 Jun 18;12(7):627
Arginine methylation of METTL14 promotes RNA N(6)-methyladenosine modification and endoderm differentiation of mouse embryonic stem cells.
Liu X, Wang H, Zhao X, Luo Q, Wang Q, Tan K, Wang Z, Jiang J, Cui J, Du E, Xia L, Du W, Chen D, Xia L, Xiao S
Nature communications 2021 Jun 18;12(1):3780
Nature communications 2021 Jun 18;12(1):3780
ALS/FTD mutations in UBQLN2 are linked to mitochondrial dysfunction through loss-of-function in mitochondrial protein import.
Lin BC, Phung TH, Higgins NR, Greenslade JE, Prado MA, Finley D, Karbowski M, Polster BM, Monteiro MJ
Human molecular genetics 2021 Jun 17;30(13):1230-1246
Human molecular genetics 2021 Jun 17;30(13):1230-1246
Single-cell RNA-seq reveals fibroblast heterogeneity and increased mesenchymal fibroblasts in human fibrotic skin diseases.
Deng CC, Hu YF, Zhu DH, Cheng Q, Gu JJ, Feng QL, Zhang LX, Xu YP, Wang D, Rong Z, Yang B
Nature communications 2021 Jun 17;12(1):3709
Nature communications 2021 Jun 17;12(1):3709
Cold Atmospheric Plasma Promotes Killing of Staphylococcus aureus by Macrophages.
Duchesne C, Frescaline N, Blaise O, Lataillade JJ, Banzet S, Dussurget O, Rousseau A
mSphere 2021 Jun 16;6(3):e0021721
mSphere 2021 Jun 16;6(3):e0021721
OGA is associated with deglycosylation of NONO and the KU complex during DNA damage repair.
Cui Y, Xie R, Zhang X, Liu Y, Hu Y, Li Y, Liu X, Yu X, Wu C
Cell death & disease 2021 Jun 16;12(7):622
Cell death & disease 2021 Jun 16;12(7):622
Exosomal SNHG16 secreted by CSCs promotes glioma development via TLR7.
Zhang R, Li P, Lv H, Li N, Ren S, Xu W
Stem cell research & therapy 2021 Jun 16;12(1):349
Stem cell research & therapy 2021 Jun 16;12(1):349
UBQLN2-HSP70 axis reduces poly-Gly-Ala aggregates and alleviates behavioral defects in the C9ORF72 animal model.
Zhang K, Wang A, Zhong K, Qi S, Wei C, Shu X, Tu WY, Xu W, Xia C, Xiao Y, Chen A, Bai L, Zhang J, Luo B, Wang W, Shen C
Neuron 2021 Jun 16;109(12):1949-1962.e6
Neuron 2021 Jun 16;109(12):1949-1962.e6
MicroRNA-139 inhibits pancreatic-cancer carcinogenesis by suppressing RalB via the Ral/RAC/PI3K pathway.
Wang Y, Zheng Y, Chen Q, Dai Y, Li T
Archives of biochemistry and biophysics 2021 Jun 15;704:108719
Archives of biochemistry and biophysics 2021 Jun 15;704:108719
Nimodipine inhibits intestinal and aortic smooth muscle contraction by regulating Ca(2+)-activated Cl(-) channels.
Wang H, Ma D, Zhu X, Liu P, Li S, Yu B, Yang H
Toxicology and applied pharmacology 2021 Jun 15;421:115543
Toxicology and applied pharmacology 2021 Jun 15;421:115543
Mechanosensitive expression of lamellipodin promotes intracellular stiffness, cyclin expression and cell proliferation.
Brazzo JA, Biber JC, Nimmer E, Heo Y, Ying L, Zhao R, Lee K, Krause M, Bae Y
Journal of cell science 2021 Jun 15;134(12)
Journal of cell science 2021 Jun 15;134(12)
Prrx1 promotes stemness and angiogenesis via activating TGF-β/smad pathway and upregulating proangiogenic factors in glioma.
Chen Z, Chen Y, Li Y, Lian W, Zheng K, Zhang Y, Zhang Y, Lin C, Liu C, Sun F, Sun X, Wang J, Zhao L, Ke Y
Cell death & disease 2021 Jun 15;12(6):615
Cell death & disease 2021 Jun 15;12(6):615
G-protein-coupled receptor GPR17 inhibits glioma development by increasing polycomb repressive complex 1-mediated ROS production.
Liu H, Xing R, Ou Z, Zhao J, Hong G, Zhao TJ, Han Y, Chen Y
Cell death & disease 2021 Jun 12;12(6):610
Cell death & disease 2021 Jun 12;12(6):610
RNF220-mediated ubiquitination promotes aggresomal accumulation and autophagic degradation of cytoplasmic Gli via HDAC6.
Wang H, Yang C, Li Y, Zhao S, Ma P, Mao B
Biochemical and biophysical research communications 2021 Jun 11;557:323-328
Biochemical and biophysical research communications 2021 Jun 11;557:323-328
Vincristine attenuates cardiac fibrosis through the inhibition of NLRP3 inflammasome activation.
Ge C, Cheng Y, Fan Y, He Y
Clinical science (London, England : 1979) 2021 Jun 11;135(11):1409-1426
Clinical science (London, England : 1979) 2021 Jun 11;135(11):1409-1426
Selenium Status in Diet Affects Acetaminophen-Induced Hepatotoxicity via Interruption of Redox Environment.
Li J, Cheng P, Li S, Zhao P, Han B, Ren X, Zhong JL, Lloyd MD, Pourzand C, Holmgren A, Lu J
Antioxidants & redox signaling 2021 Jun 10;34(17):1355-1367
Antioxidants & redox signaling 2021 Jun 10;34(17):1355-1367
STAT1 epigenetically regulates LCP2 and TNFAIP2 by recruiting EP300 to contribute to the pathogenesis of inflammatory bowel disease.
Yu YL, Chen M, Zhu H, Zhuo MX, Chen P, Mao YJ, Li LY, Zhao Q, Wu M, Ye M
Clinical epigenetics 2021 Jun 10;13(1):127
Clinical epigenetics 2021 Jun 10;13(1):127
Reducing lipofuscin accumulation and cardiomyocytic senescence of aging heart by enhancing autophagy.
Li WW, Wang HJ, Tan YZ, Wang YL, Yu SN, Li ZH
Experimental cell research 2021 Jun 1;403(1):112585
Experimental cell research 2021 Jun 1;403(1):112585
Tumors exploit FTO-mediated regulation of glycolytic metabolism to evade immune surveillance.
Liu Y, Liang G, Xu H, Dong W, Dong Z, Qiu Z, Zhang Z, Li F, Huang Y, Li Y, Wu J, Yin S, Zhang Y, Guo P, Liu J, Xi JJ, Jiang P, Han D, Yang CG, Xu MM
Cell metabolism 2021 Jun 1;33(6):1221-1233.e11
Cell metabolism 2021 Jun 1;33(6):1221-1233.e11
A kinome screen reveals that Nemo-like kinase is a key suppressor of hepatic gluconeogenesis.
Ji YX, Wang Y, Li PL, Cai L, Wang XM, Bai L, Liu Z, Tian H, Tian S, Zhang P, Zhang XJ, Cheng X, Yuan Y, She ZG, Hu Y, Li H
Cell metabolism 2021 Jun 1;33(6):1171-1186.e9
Cell metabolism 2021 Jun 1;33(6):1171-1186.e9
VEGF/Src signaling mediated pleural barrier damage and increased permeability contributes to subpleural pulmonary fibrosis.
Lu YZ, Liang LM, Cheng PP, Xiong L, Wang M, Song LJ, Yu F, He XL, Xiong L, Wang XR, Xin JB, Ye H, Ma WL
American journal of physiology. Lung cellular and molecular physiology 2021 Jun 1;320(6):L990-L1004
American journal of physiology. Lung cellular and molecular physiology 2021 Jun 1;320(6):L990-L1004
High uric acid induces liver fat accumulation via ROS/JNK/AP-1 signaling.
Xie D, Zhao H, Lu J, He F, Liu W, Yu W, Wang Q, Hisatome I, Yamamoto T, Koyama H, Cheng J
American journal of physiology. Endocrinology and metabolism 2021 Jun 1;320(6):E1032-E1043
American journal of physiology. Endocrinology and metabolism 2021 Jun 1;320(6):E1032-E1043
THAP11 down-regulation may contribute to cardio-protective effects of sevoflurane anesthesia: Evidence from clinical and molecular evidence.
Duan Z, Zhou X, Chen F, Chen H, Duan G, Li H
Life sciences 2021 Jun 1;274:119327
Life sciences 2021 Jun 1;274:119327
Nicotinamide mononucleotide attenuates isoproterenol-induced cardiac fibrosis by regulating oxidative stress and Smad3 acetylation.
Wu K, Li B, Lin Q, Xu W, Zuo W, Li J, Liu N, Tu T, Zhang B, Xiao Y, Liu Q
Life sciences 2021 Jun 1;274:119299
Life sciences 2021 Jun 1;274:119299
MIR29A Impedes Metastatic Behaviors in Hepatocellular Carcinoma via Targeting LOX, LOXL2, and VEGFA.
Yang YL, Tsai MC, Chang YH, Wang CC, Chu PY, Lin HY, Huang YH
International journal of molecular sciences 2021 Jun 1;22(11)
International journal of molecular sciences 2021 Jun 1;22(11)
Inducible ATP1B1 Upregulates Antiviral Innate Immune Responses by the Ubiquitination of TRAF3 and TRAF6.
Cao W, Guo Y, Cheng Z, Xu G, Zuo Q, Nie L, Huang Y, Liu S, Zhu Y
Journal of immunology (Baltimore, Md. : 1950) 2021 Jun 1;206(11):2668-2681
Journal of immunology (Baltimore, Md. : 1950) 2021 Jun 1;206(11):2668-2681
Microglial IL-10 and β-endorphin expression mediates gabapentinoids antineuropathic pain.
Ahmad KA, Shoaib RM, Ahsan MZ, Deng MY, Ma L, Apryani E, Li XY, Wang YX
Brain, behavior, and immunity 2021 Jul;95:344-361
Brain, behavior, and immunity 2021 Jul;95:344-361
Expression of Cntn1 is regulated by stress and associated with anxiety and depression phenotypes.
Li S, Cao W, Zhou S, Ma M, Zhang W, Li F, Li C
Brain, behavior, and immunity 2021 Jul;95:142-153
Brain, behavior, and immunity 2021 Jul;95:142-153
GCH1 induces immunosuppression through metabolic reprogramming and IDO1 upregulation in triple-negative breast cancer.
Wei JL, Wu SY, Yang YS, Xiao Y, Jin X, Xu XE, Hu X, Li DQ, Jiang YZ, Shao ZM
Journal for immunotherapy of cancer 2021 Jul;9(7)
Journal for immunotherapy of cancer 2021 Jul;9(7)
MiR-519d-5p modulates the sensitivity of breast cancer to chemotherapy by forming a negative feedback loop with RELA.
Li D, Wang T, Yu Z, Zhang Y, Wu X, Zheng N, Zhang W, Wu L
Annals of translational medicine 2021 Jul;9(14):1171
Annals of translational medicine 2021 Jul;9(14):1171
LXRβ is involved in the control of platelet production from megakaryocytes.
Wan YW, Liu W, Feng MT, Pu J, Zhuang SW, He B, Liu X
Blood cells, molecules & diseases 2021 Jul;89:102568
Blood cells, molecules & diseases 2021 Jul;89:102568
Wireless Localized Electrical Stimulation Generated by an Ultrasound-Driven Piezoelectric Discharge Regulates Proinflammatory Macrophage Polarization.
Kong Y, Liu F, Ma B, Duan J, Yuan W, Sang Y, Han L, Wang S, Liu H
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2021 Jul;8(13):2100962
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2021 Jul;8(13):2100962
Multiregional profiling of the brain transmembrane proteome uncovers novel regulators of depression.
Li S, Luo H, Lou R, Tian C, Miao C, Xia L, Pan C, Duan X, Dang T, Li H, Fan C, Tang P, Zhang Z, Liu Y, Li Y, Xu F, Zhang Y, Zhong G, Hu J, Shui W
Science advances 2021 Jul;7(30)
Science advances 2021 Jul;7(30)
Sulforaphane Balances Ca(2+) Homeostasis Injured by Excessive Fat via Mitochondria-Associated Membrane (MAM).
Tian S, Lei P, Zhang J, Sun Y, Li B, Shan Y
Molecular nutrition & food research 2021 Jul;65(14):e2001076
Molecular nutrition & food research 2021 Jul;65(14):e2001076
Enhancing immunogenicity of HPV16 E(7) DNA vaccine by conjugating codon-optimized GM-CSF to HPV16 E(7) DNA.
Chen YP, Lin CC, Xie YX, Chen CY, Qiu JT
Taiwanese journal of obstetrics & gynecology 2021 Jul;60(4):700-705
Taiwanese journal of obstetrics & gynecology 2021 Jul;60(4):700-705
The LncRNA RP11-279C4.1 Enhances the Malignant Behaviour of Glioma Cells and Glioma Stem-Like Cells by Regulating the miR-1273g-3p/CBX3 Axis.
Wang F, Zhang L, Luo Y, Zhang Q, Zhang Y, Shao Y, Yuan L
Molecular neurobiology 2021 Jul;58(7):3362-3373
Molecular neurobiology 2021 Jul;58(7):3362-3373
Generation of a TLR2 homozygous knockout human embryonic stem cell line WAe001-A-64 using CRISPR/Cas9 editing.
Getachew A, Yang Z, Huang X, Wu F, Liu YY, Yan C, Yang F, Li Y
Stem cell research 2021 Jul;54:102401
Stem cell research 2021 Jul;54:102401
Neutrophil extracellular traps promote gastric cancer metastasis by inducing epithelial‑mesenchymal transition.
Zhu T, Zou X, Yang C, Li L, Wang B, Li R, Li H, Xu Z, Huang D, Wu Q
International journal of molecular medicine 2021 Jul;48(1)
International journal of molecular medicine 2021 Jul;48(1)
Selenium triggers Nrf2-AMPK crosstalk to alleviate cadmium-induced autophagy in rabbit cerebrum.
Xue H, Cao H, Xing C, Feng J, Zhang L, Zhang C, Hu G, Yang F
Toxicology 2021 Jul;459:152855
Toxicology 2021 Jul;459:152855
EZH2 regulates expression of FOXC1 by mediating H3K27me3 in breast cancers.
Zheng XJ, Li W, Yi J, Liu JY, Ren LW, Zhu XM, Liu SW, Wang JH, Du GH
Acta pharmacologica Sinica 2021 Jul;42(7):1171-1179
Acta pharmacologica Sinica 2021 Jul;42(7):1171-1179
Exosomes are involved in total body irradiation-induced intestinal injury in mice.
Li H, Jiang M, Zhao SY, Zhang SQ, Lu L, He X, Feng GX, Wu X, Fan SJ
Acta pharmacologica Sinica 2021 Jul;42(7):1111-1123
Acta pharmacologica Sinica 2021 Jul;42(7):1111-1123
YB1 regulates miR-205/200b-ZEB1 axis by inhibiting microRNA maturation in hepatocellular carcinoma.
Liu X, Chen D, Chen H, Wang W, Liu Y, Wang Y, Duan C, Ning Z, Guo X, Otkur W, Liu J, Qi H, Liu X, Lin A, Xia T, Liu HX, Piao HL
Cancer communications (London, England) 2021 Jul;41(7):576-595
Cancer communications (London, England) 2021 Jul;41(7):576-595
A multifaceted role of progranulin in regulating amyloid-beta dynamics and responses.
Du H, Wong MY, Zhang T, Santos MN, Hsu C, Zhang J, Yu H, Luo W, Hu F
Life science alliance 2021 Jul;4(7)
Life science alliance 2021 Jul;4(7)
MiR-706 alleviates white matter injury via downregulating PKCα/MST1/NF-κB pathway after subarachnoid hemorrhage in mice.
Ru X, Qu J, Li Q, Zhou J, Huang S, Li W, Zuo S, Chen Y, Liu Z, Feng H
Experimental neurology 2021 Jul;341:113688
Experimental neurology 2021 Jul;341:113688
Direct control of store-operated calcium channels by ultrafast laser.
Cheng P, Tian X, Tang W, Cheng J, Bao J, Wang H, Zheng S, Wang Y, Wei X, Chen T, Feng H, Xue T, Goda K, He H
Cell research 2021 Jul;31(7):758-772
Cell research 2021 Jul;31(7):758-772
Aflatoxin B1 inhibited autophagy flux by inducing lysosomal alkalinization in HepG2 cells.
Zhang Q, Feng Z, Lu J, Lu J, Guan S, Chen Y
Toxicology mechanisms and methods 2021 Jul;31(6):450-456
Toxicology mechanisms and methods 2021 Jul;31(6):450-456
MicroRNA-215-5p inhibits the proliferation of keratinocytes and alleviates psoriasis-like inflammation by negatively regulating DYRK1A and its downstream signalling pathways.
Liu A, Zhang B, Zhao W, Tu Y, Wang Q, Li J
Experimental dermatology 2021 Jul;30(7):932-942
Experimental dermatology 2021 Jul;30(7):932-942
Mechanistic insights into mitochondrial tRNA(Ala) 3'-end metabolism deficiency.
Ji Y, Nie Z, Meng F, Hu C, Chen H, Jin L, Chen M, Zhang M, Zhang J, Liang M, Wang M, Guan MX
The Journal of biological chemistry 2021 Jul;297(1):100816
The Journal of biological chemistry 2021 Jul;297(1):100816
MACF1 promotes osteoblast differentiation by sequestering repressors in cytoplasm.
Hu L, Yin C, Chen D, Wu Z, Liang S, Zhang Y, Huang Z, Liu S, Xu X, Chen Z, Zhang Y, Qian A
Cell death and differentiation 2021 Jul;28(7):2160-2178
Cell death and differentiation 2021 Jul;28(7):2160-2178
Overexpression of SERPINA3 promotes tumor invasion and migration, epithelial-mesenchymal-transition in triple-negative breast cancer cells.
Zhang Y, Tian J, Qu C, Peng Y, Lei J, Li K, Zong B, Sun L, Liu S
Breast cancer (Tokyo, Japan) 2021 Jul;28(4):859-873
Breast cancer (Tokyo, Japan) 2021 Jul;28(4):859-873
Human umbilical cord mesenchymal stem cell-derived exosomes inhibit migration and invasion of breast cancer cells via miR-21-5p/ZNF367 pathway.
Du L, Tao X, Shen X
Breast cancer (Tokyo, Japan) 2021 Jul;28(4):829-837
Breast cancer (Tokyo, Japan) 2021 Jul;28(4):829-837
Caspase-1 inhibits IFN-β production via cleavage of cGAS during M. bovis infection.
Liao Y, Liu C, Wang J, Song Y, Sabir N, Hussain T, Yao J, Luo L, Wang H, Cui Y, Yang L, Zhao D, Zhou X
Veterinary microbiology 2021 Jul;258:109126
Veterinary microbiology 2021 Jul;258:109126
METTL16 promotes cell proliferation by up-regulating cyclin D1 expression in gastric cancer.
Wang XK, Zhang YW, Wang CM, Li B, Zhang TZ, Zhou WJ, Cheng LJ, Huo MY, Zhang CH, He YL
Journal of cellular and molecular medicine 2021 Jul;25(14):6602-6617
Journal of cellular and molecular medicine 2021 Jul;25(14):6602-6617
Gankyrin activates the hedgehog signalling to drive metastasis in osteosarcoma.
Wang C, Jing J, Hu X, Yu S, Yao F, Li Z, Cheng L
Journal of cellular and molecular medicine 2021 Jul;25(13):6232-6241
Journal of cellular and molecular medicine 2021 Jul;25(13):6232-6241
Different roles of BAG3 in cardiac physiological hypertrophy and pathological remodeling.
Jia P, Wu N, Yang H, Guo Y, Guo X, Sun Y
Translational research : the journal of laboratory and clinical medicine 2021 Jul;233:47-61
Translational research : the journal of laboratory and clinical medicine 2021 Jul;233:47-61
Cancer cell-intrinsic STING is associated with CD8 + T-cell infiltration and might serve as a potential immunotherapeutic target in hepatocellular carcinoma.
Zhang Y, Zhai Q, Feng X, Chen D, Lu Y, Hu J, Xie H, Zhou L, Wu J, Zheng S
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 2021 Jul;23(7):1314-1324
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 2021 Jul;23(7):1314-1324
Effects of TRIM59 on RAW264.7 macrophage gene expression and function.
Jin Z, Zhu Z, Zhang W, Liu L, Tang M, Li D, Yan D, Zhu X
Immunobiology 2021 Jul;226(4):152109
Immunobiology 2021 Jul;226(4):152109
Mechanism of validamycin A inhibiting DON biosynthesis and synergizing with DMI fungicides against Fusarium graminearum.
Bian C, Duan Y, Xiu Q, Wang J, Tao X, Zhou M
Molecular plant pathology 2021 Jul;22(7):769-785
Molecular plant pathology 2021 Jul;22(7):769-785
Effect of the interference with DRP1 expression on the biological characteristics of glioma stem cells.
Zhang L, Cao H, Tao H, Yang J, Gong W, Hu Q
Experimental and therapeutic medicine 2021 Jul;22(1):696
Experimental and therapeutic medicine 2021 Jul;22(1):696
C1orf61 promotes hepatocellular carcinoma metastasis and increases the therapeutic response to sorafenib.
Yu Y, Wang Z, Huang Z, Tang X, Huang X, Li W
Biochimica et biophysica acta. Molecular cell research 2021 Jul;1868(8):119048
Biochimica et biophysica acta. Molecular cell research 2021 Jul;1868(8):119048
Metabolomic profiling of single enlarged lysosomes.
Zhu H, Li Q, Liao T, Yin X, Chen Q, Wang Z, Dai M, Yi L, Ge S, Miao C, Zeng W, Qu L, Ju Z, Huang G, Cang C, Xiong W
Nature methods 2021 Jul;18(7):788-798
Nature methods 2021 Jul;18(7):788-798
Activation of Ca(2+)/Calmodulin-Dependent Protein Kinase II (CaMKII) with Lidocaine Provokes Pyroptosis of Glioblastoma Cells.
Zhou B, Lin Y, Chen S, Cai J, Luo Z, Yu S, Lu J
Bulletin of experimental biology and medicine 2021 Jul;171(3):297-304
Bulletin of experimental biology and medicine 2021 Jul;171(3):297-304
SNX17 protects the heart from doxorubicin-induced cardiotoxicity by modulating LMOD2 degradation.
Zhang Y, Ni L, Lin B, Hu L, Lin Z, Yang J, Wang J, Ma H, Liu Y, Yang J, Lin J, Xu L, Wu L, Shi D
Pharmacological research 2021 Jul;169:105642
Pharmacological research 2021 Jul;169:105642
Dihydrotanshinone I inhibits aortic valve interstitial cell calcification via the SMAD1/5/8/NF-κB/ERK pathway.
Wang Y, Weng Y, Li X, Huang Q, Xiang Y, Li X, Shi Q
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Jul;139:111674
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Jul;139:111674
Fucoxanthin rescues dexamethasone induced C2C12 myotubes atrophy.
Zhiyin L, Jinliang C, Qiunan C, Yunfei Y, Qian X
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Jul;139:111590
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Jul;139:111590
Tacrolimus inhibits oral carcinogenesis through cell cycle control.
Li Y, Wang Y, Li J, Ling Z, Chen W, Zhang L, Hu Q, Wu T, Cheng B, Wang Y, Xia J
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Jul;139:111545
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Jul;139:111545
Choline attenuates heat stress-induced oxidative injury and apoptosis in bovine mammary epithelial cells by modulating PERK/Nrf-2 signaling pathway.
Yang M, Kuang M, Wang G, Ali I, Tang Y, Yang C, Li Y, Li L
Molecular immunology 2021 Jul;135:388-397
Molecular immunology 2021 Jul;135:388-397
Brevilin A inhibits NLRP3 inflammasome activation in vivo and in vitro by acting on the upstream of NLRP3-induced ASC oligomerization.
Qin Q, Xu G, Zhan X, Wang Z, Wang Y, Liu H, Hou X, Shi W, Ma J, Bai Z, Xiao X
Molecular immunology 2021 Jul;135:116-126
Molecular immunology 2021 Jul;135:116-126
Upregulation of estrogen receptor beta protein but not mRNA predicts poor prognosis and may be associated with enhanced translation in non-small cell lung cancer: a systematic review and meta-analysis.
Meng W, Liao Y, Chen J, Wang Y, Meng Y, Li K, Xiao H
Journal of thoracic disease 2021 Jul;13(7):4281-4300
Journal of thoracic disease 2021 Jul;13(7):4281-4300
ASAP1 regulates the uptake of Mycobacterium tuberculosis H37Ra in THP1-derived macrophages by remodeling actin cytoskeleton.
Cui J, Chen G, Zhao Z, Wang L, Wen D, Xing L, Wu C
Tuberculosis (Edinburgh, Scotland) 2021 Jul;129:102090
Tuberculosis (Edinburgh, Scotland) 2021 Jul;129:102090
Calycosin attenuates pulmonary fibrosis by the epithelial-mesenchymal transition repression upon inhibiting the AKT/GSK3β/β-catenin signaling pathway.
Liu X, Shao Y, Zhang X, Ji X, Xie M, Liu H
Acta histochemica 2021 Jul;123(5):151746
Acta histochemica 2021 Jul;123(5):151746
KIN17 promotes tumor metastasis by activating EMT signaling in luminal-A breast cancer.
Huang Q, Zahid KR, Chen J, Pang X, Zhong M, Huang H, Pan W, Yin J, Raza U, Zeng J, Zhu X, Zeng T
Thoracic cancer 2021 Jul;12(13):2013-2023
Thoracic cancer 2021 Jul;12(13):2013-2023
C188-9 reduces TGF-β1-induced fibroblast activation and alleviates ISO-induced cardiac fibrosis in mice.
Liu J, Jin Y, Wang B, Zhang J, Zuo S
FEBS open bio 2021 Jul;11(7):2033-2040
FEBS open bio 2021 Jul;11(7):2033-2040
Protective effects of VMY-2-95 on corticosterone-induced injuries in mice and cellular models.
Yu Z, Kong D, Liang Y, Zhao X, Du G
Acta pharmaceutica Sinica. B 2021 Jul;11(7):1903-1913
Acta pharmaceutica Sinica. B 2021 Jul;11(7):1903-1913
miRNA-194 predicts favorable prognosis in gastric cancer and inhibits gastric cancer cell growth by targeting CCND1.
Wang J, Zhang M, Hu X, She J, Sun R, Qin S, Li D
FEBS open bio 2021 Jul;11(7):1814-1826
FEBS open bio 2021 Jul;11(7):1814-1826
Murine Ifit3 restricts the replication of Rabies virus both in vitro and in vivo.
Chai B, Tian D, Zhou M, Tian B, Yuan Y, Sui B, Wang K, Pei J, Huang F, Wu Q, Lv L, Yang Y, Wang C, Fu Z, Zhao L
The Journal of general virology 2021 Jul;102(7)
The Journal of general virology 2021 Jul;102(7)
Tubeimoside I improves endothelial function in sepsis via activation of SIRT3.
Yang X, Li X, Luo M, Li C, Huang L, Li X, Huang B, Shen J, Luo S, Yan J
Laboratory investigation; a journal of technical methods and pathology 2021 Jul;101(7):897-907
Laboratory investigation; a journal of technical methods and pathology 2021 Jul;101(7):897-907
The Sonic Hedgehog signaling pathway regulates autophagy and migration in ovarian cancer.
Pan Y, Zhou J, Zhang W, Yan L, Lu M, Dai Y, Zhou H, Zhang S, Yang J
Cancer medicine 2021 Jul;10(13):4510-4521
Cancer medicine 2021 Jul;10(13):4510-4521
Discovery of β-Carboline Derivatives as a Highly Potent Cardioprotectant against Myocardial Ischemia-Reperfusion Injury.
Zhang H, Zhang RH, Liao XM, Yang D, Wang YC, Zhao YL, Xu GB, Liu CH, Li YJ, Liao SG, Zhou M
Journal of medicinal chemistry 2021 Jul 8;64(13):9166-9181
Journal of medicinal chemistry 2021 Jul 8;64(13):9166-9181
YBX1 is required for maintaining myeloid leukemia cell survival by regulating BCL2 stability in an m6A-dependent manner.
Feng M, Xie X, Han G, Zhang T, Li Y, Li Y, Yin R, Wang Q, Zhang T, Wang P, Hu J, Cheng Y, Gao Z, Wang J, Chang J, Cui M, Gao K, Chai J, Liu W, Guo C, Li S, Liu L, Zhou F, Chen J, Zhang H
Blood 2021 Jul 8;138(1):71-85
Blood 2021 Jul 8;138(1):71-85
Intestinal Klebsiella pneumoniae infection enhances susceptibility to epileptic seizure which can be reduced by microglia activation.
Lin P, Lin A, Tao K, Yang M, Ye Q, Chen H, Chen Y, Ma Y, Lin Z, He M, Wang X, Tian X
Cell death discovery 2021 Jul 7;7(1):175
Cell death discovery 2021 Jul 7;7(1):175
Inhibition of xCT suppresses the efficacy of anti-PD-1/L1 melanoma treatment through exosomal PD-L1-induced macrophage M2 polarization.
Liu N, Zhang J, Yin M, Liu H, Zhang X, Li J, Yan B, Guo Y, Zhou J, Tao J, Hu S, Chen X, Peng C
Molecular therapy : the journal of the American Society of Gene Therapy 2021 Jul 7;29(7):2321-2334
Molecular therapy : the journal of the American Society of Gene Therapy 2021 Jul 7;29(7):2321-2334
The cardiac translational landscape reveals that micropeptides are new players involved in cardiomyocyte hypertrophy.
Yan Y, Tang R, Li B, Cheng L, Ye S, Yang T, Han YC, Liu C, Dong Y, Qu LH, Lui KO, Yang JH, Huang ZP
Molecular therapy : the journal of the American Society of Gene Therapy 2021 Jul 7;29(7):2253-2267
Molecular therapy : the journal of the American Society of Gene Therapy 2021 Jul 7;29(7):2253-2267
Prognostic signature composed of transcription factors accurately predicts the prognosis of gastric cancer patients.
Zhou L, Chen Z, Wu Y, Lu H, Xin L
Cancer cell international 2021 Jul 7;21(1):357
Cancer cell international 2021 Jul 7;21(1):357
Participation of Mind Bomb-2 in Sevoflurane Anesthesia Induces Cognitive Impairment in Aged Mice via Modulating Ferroptosis.
Zhao L, Gong H, Huang H, Tuerhong G, Xia H
ACS chemical neuroscience 2021 Jul 7;12(13):2399-2408
ACS chemical neuroscience 2021 Jul 7;12(13):2399-2408
USP19 promotes hypoxia-induced mitochondrial division via FUNDC1 at ER-mitochondria contact sites.
Chai P, Cheng Y, Hou C, Yin L, Zhang D, Hu Y, Chen Q, Zheng P, Teng J, Chen J
The Journal of cell biology 2021 Jul 5;220(7)
The Journal of cell biology 2021 Jul 5;220(7)
Identification and optimization of 3-bromo-N'-(4-hydroxybenzylidene)-4-methylbenzohydrazide derivatives as mTOR inhibitors that induce autophagic cell death and apoptosis in triple-negative breast cancer.
Xu T, Zhang J, Yang C, Pluta R, Wang G, Ye T, Ouyang L
European journal of medicinal chemistry 2021 Jul 5;219:113424
European journal of medicinal chemistry 2021 Jul 5;219:113424
The intrinsic role and mechanism of tumor expressed-CD38 on lung adenocarcinoma progression.
Gao L, Liu Y, Du X, Ma S, Ge M, Tang H, Han C, Zhao X, Liu Y, Shao Y, Wu Z, Zhang L, Meng F, Xiao-Feng Qin F
Cell death & disease 2021 Jul 5;12(7):680
Cell death & disease 2021 Jul 5;12(7):680
A flavonoid-rich Smilax china L. extract prevents obesity by upregulating the adiponectin-receptor/AMPK signalling pathway and modulating the gut microbiota in mice.
Li X, Yang L, Li J, Lin L, Zheng G
Food & function 2021 Jul 5;12(13):5862-5875
Food & function 2021 Jul 5;12(13):5862-5875
Lnc-STYK1-2 regulates bladder cancer cell proliferation, migration, and invasion by targeting miR-146b-5p expression and AKT/STAT3/NF-kB signaling.
Dai R, Jiang Q, Zhou Y, Lin R, Lin H, Zhang Y, Zhang J, Gao X
Cancer cell international 2021 Jul 31;21(1):408
Cancer cell international 2021 Jul 31;21(1):408
Integrated bioinformatics analysis revealed the regulation of angiogenesis by tumor cells in hepatocellular carcinoma.
Huo M, Yu K, Zheng Y, Liu L, Zhao H, Li X, Huang C, Zhang J
Bioscience reports 2021 Jul 30;41(7)
Bioscience reports 2021 Jul 30;41(7)
Anti-anemia drug FG4592 retards the AKI-to-CKD transition by improving vascular regeneration and antioxidative capability.
Wu M, Chen W, Miao M, Jin Q, Zhang S, Bai M, Fan J, Zhang Y, Zhang A, Jia Z, Huang S
Clinical science (London, England : 1979) 2021 Jul 30;135(14):1707-1726
Clinical science (London, England : 1979) 2021 Jul 30;135(14):1707-1726
Glycoursodeoxycholic acid ameliorates diet-induced metabolic disorders with inhibiting endoplasmic reticulum stress.
Cheng L, Chen T, Guo M, Liu P, Qiao X, Wei Y, She J, Li B, Xi W, Zhou J, Yuan Z, Wu Y, Liu J
Clinical science (London, England : 1979) 2021 Jul 30;135(14):1689-1706
Clinical science (London, England : 1979) 2021 Jul 30;135(14):1689-1706
Propofol differentially induces unconsciousness and respiratory depression through distinct interactions between GABAA receptor and GABAergic neuron in corresponding nuclei.
Jiang J, Jiao Y, Gao P, Yin W, Zhou W, Zhang Y, Liu Y, Wen D, Wang Y, Zhou L, Yu T, Yu W
Acta biochimica et biophysica Sinica 2021 Jul 28;53(8):1076-1087
Acta biochimica et biophysica Sinica 2021 Jul 28;53(8):1076-1087
TBN improves motor function and prolongs survival in a TDP-43M337V mouse model of ALS.
Huang C, Li J, Zhang G, Lin Y, Li C, Zheng X, Song X, Han B, Guo B, Tu Z, Zhang J, Sun Y, Wang Y, Zhang Z, Yan S
Human molecular genetics 2021 Jul 28;30(16):1484-1496
Human molecular genetics 2021 Jul 28;30(16):1484-1496
Pterostilbene alleviates pulmonary fibrosis by regulating ASIC2.
Peng Y, Zhang Y, Zhang Y, Wang X, Xia Y
Chinese medicine 2021 Jul 28;16(1):66
Chinese medicine 2021 Jul 28;16(1):66
Analysis of the Internal Hypoxic Environment in Solid Tumor Tissue Using a Folding Paper System.
Huang CH, Chong KY, Lei KF
ACS applied materials & interfaces 2021 Jul 28;13(29):33885-33893
ACS applied materials & interfaces 2021 Jul 28;13(29):33885-33893
The anti-dysenteric drug fraxetin enhances anti-tumor efficacy of gemcitabine and suppresses pancreatic cancer development by antagonizing STAT3 activation.
Guo Y, Xiao Y, Guo H, Zhu H, Chen D, Wang J, Deng J, Lan J, Liu X, Zhang Q, Bai Y
Aging 2021 Jul 28;13(14):18545-18563
Aging 2021 Jul 28;13(14):18545-18563
MINDY1 promotes bladder cancer progression by stabilizing YAP.
Luo Y, Zhou J, Tang J, Zhou F, He Z, Liu T, Liu T
Cancer cell international 2021 Jul 27;21(1):395
Cancer cell international 2021 Jul 27;21(1):395
Serum exosomes from young rats improve the reduced osteogenic differentiation of BMSCs in aged rats with osteoporosis after fatigue loading in vivo.
Xun J, Li C, Liu M, Mei Y, Zhou Q, Wu B, Xie F, Liu Y, Dai R
Stem cell research & therapy 2021 Jul 27;12(1):424
Stem cell research & therapy 2021 Jul 27;12(1):424
Tree Shrew Cells Transduced with Human CD4 and CCR5 Support Early Steps of HIV-1 Replication, but Viral Infectivity Is Restricted by APOBEC3.
Luo MT, Mu D, Yang X, Luo RH, Zheng HY, Chen M, Guo YQ, Zheng YT
Journal of virology 2021 Jul 26;95(16):e0002021
Journal of virology 2021 Jul 26;95(16):e0002021
Nuclear iASPP determines cell fate by selectively inhibiting either p53 or NF-κB.
Ge W, Wang Y, Zheng S, Zhao D, Wang X, Zhang X, Hu Y
Cell death discovery 2021 Jul 26;7(1):195
Cell death discovery 2021 Jul 26;7(1):195
GNAI2 Promotes Proliferation and Decreases Apoptosis in Rabbit Melanocytes.
Hu S, Dai Y, Bai S, Zhao B, Wu X, Chen Y
Genes 2021 Jul 25;12(8)
Genes 2021 Jul 25;12(8)
Behavioral effects of early-life exposure to perfluorooctanoic acid might synthetically link to multiple aspects of dopaminergic neuron development and dopamine functions in zebrafish larvae.
Yu T, Zhou G, Cai Z, Liang W, Du Y, Wang W
Aquatic toxicology (Amsterdam, Netherlands) 2021 Jul 24;238:105926
Aquatic toxicology (Amsterdam, Netherlands) 2021 Jul 24;238:105926
Phenethylamine in chlorella alleviates high-fat diet-induced mouse liver damage by regulating generation of methylglyoxal.
Zheng Y, Martin-Morales A, Wang J, Fujishima M, Okumura E, Sato K
NPJ science of food 2021 Jul 23;5(1):22
NPJ science of food 2021 Jul 23;5(1):22
A CREB1-miR-181a-5p loop regulates the pathophysiologic features of bone marrow stromal cells in fibrous dysplasia of bone.
Fu Y, Xin Z, Ling Z, Xie H, Xiao T, Shen X, Lin J, Xu L, Jiang H
Molecular medicine (Cambridge, Mass.) 2021 Jul 22;27(1):81
Molecular medicine (Cambridge, Mass.) 2021 Jul 22;27(1):81
Autophagy-related circRNA evaluation reveals hsa_circ_0001747 as a potential favorable prognostic factor for biochemical recurrence in patients with prostate cancer.
Zhong C, Wu K, Wang S, Long Z, Yang T, Zhong W, Tan X, Wang Z, Li C, Lu J, Mao X
Cell death & disease 2021 Jul 22;12(8):726
Cell death & disease 2021 Jul 22;12(8):726
Role of MCP-1 and IL-8 in viral anterior uveitis, and contractility and fibrogenic activity of trabecular meshwork cells.
Lee J, Choi JA, Ju HH, Kim JE, Paik SY, Rao PV
Scientific reports 2021 Jul 22;11(1):14950
Scientific reports 2021 Jul 22;11(1):14950
Epitranscriptomic editing of the RNA N6-methyladenosine modification by dCasRx conjugated methyltransferase and demethylase.
Xia Z, Tang M, Ma J, Zhang H, Gimple RC, Prager BC, Tang H, Sun C, Liu F, Lin P, Mei Y, Du R, Rich JN, Xie Q
Nucleic acids research 2021 Jul 21;49(13):7361-7374
Nucleic acids research 2021 Jul 21;49(13):7361-7374
Lactate secreted by PKM2 upregulation promotes Galectin-9-mediated immunosuppression via inhibiting NF-κB pathway in HNSCC.
Chang H, Xu Q, Li J, Li M, Zhang Z, Ma H, Yang X
Cell death & disease 2021 Jul 21;12(8):725
Cell death & disease 2021 Jul 21;12(8):725
SARS-CoV-2 Restructures the Host Chromatin Architecture.
Wang R, Lee JH, Xiong F, Kim J, Al Hasani L, Yuan X, Shivshankar P, Krakowiak J, Qi C, Wang Y, Eltzschig HK, Li W
bioRxiv : the preprint server for biology 2021 Jul 21;
bioRxiv : the preprint server for biology 2021 Jul 21;
Comparable radiation sensitivity in p53 wild-type and p53 deficient tumor cells associated with different cell death modalities.
Li P, Liu X, Zhao T, Li F, Wang Q, Zhang P, Hirayama R, Chen W, Jin X, Zheng X, Wang Z, Li Q
Cell death discovery 2021 Jul 20;7(1):184
Cell death discovery 2021 Jul 20;7(1):184
A mesenchymal-like subpopulation in non-neuroendocrine SCLC contributes to metastasis.
Jin Y, Xiao T, Feng Y, Yang J, Guo C, Hu L, Ji H
Journal of genetics and genomics = Yi chuan xue bao 2021 Jul 20;48(7):571-581
Journal of genetics and genomics = Yi chuan xue bao 2021 Jul 20;48(7):571-581
TGF-β1-mediated exosomal lnc-MMP2-2 increases blood-brain barrier permeability via the miRNA-1207-5p/EPB41L5 axis to promote non-small cell lung cancer brain metastasis.
Wu D, Deng S, Li L, Liu T, Zhang T, Li J, Yu Y, Xu Y
Cell death & disease 2021 Jul 20;12(8):721
Cell death & disease 2021 Jul 20;12(8):721
Inactivation of the tumor suppressor p53 by long noncoding RNA RMRP.
Chen Y, Hao Q, Wang S, Cao M, Huang Y, Weng X, Wang J, Zhang Z, He X, Lu H, Zhou X
Proceedings of the National Academy of Sciences of the United States of America 2021 Jul 20;118(29)
Proceedings of the National Academy of Sciences of the United States of America 2021 Jul 20;118(29)
Variations in Env at amino acids 328 and 330 affect HIV-1 replicative fitness and entry inhibitor sensitivity.
Wang H, Li Y, Li Y, Li B, Zhu X, Yan D, Li M, Wu W, Sun M, Yang R
Virus research 2021 Jul 2;299:198424
Virus research 2021 Jul 2;299:198424
The molecular basis of coupling between poly(A)-tail length and translational efficiency.
Xiang K, Bartel DP
eLife 2021 Jul 2;10
eLife 2021 Jul 2;10
MALDI-MS-based biomarker analysis of extracellular vesicles from human lung carcinoma cells.
Yu Z, Zhao C, Hu S, Zhang H, Li W, Zhang R, Luo Q, Yang H
RSC advances 2021 Jul 19;11(41):25375-25380
RSC advances 2021 Jul 19;11(41):25375-25380
MARCH6 promotes hepatocellular carcinoma development through up-regulation of ATF2.
Sun J, Dong Z, Chang Z, Liu H, Jiang Q, Zhang D, Lu S, Jia X, Wu D, Ge A, Zhao P, Wang J, Lu Y
BMC cancer 2021 Jul 17;21(1):827
BMC cancer 2021 Jul 17;21(1):827
Erlotinib protests against LPS-induced parthanatos through inhibiting macrophage surface TLR4 expression.
Xue Q, Liu X, Chen C, Zhang X, Xie P, Liu Y, Zhou S, Tang J
Cell death discovery 2021 Jul 16;7(1):181
Cell death discovery 2021 Jul 16;7(1):181
BMI1 activates P-glycoprotein via transcription repression of miR-3682-3p and enhances chemoresistance of bladder cancer cell.
Chen MK, Zhou JH, Wang P, Ye YL, Liu Y, Zhou JW, Chen ZJ, Yang JK, Liao DY, Liang ZJ, Xie X, Zhou QZ, Xue KY, Guo WB, Xia M, Bao JM, Yang C, Duan HF, Wang HY, Huang ZP, Qin ZK, Liu CD
Aging 2021 Jul 16;13(14):18310-18330
Aging 2021 Jul 16;13(14):18310-18330
Role of NLR family pyrin domain-containing 3 inflammasome in the activation of pancreatic stellate cells.
Li CX, Cui LH, Zhang LQ, Yang L, Zhuo YZ, Cui NQ, Zhang SK
Experimental cell research 2021 Jul 15;404(2):112634
Experimental cell research 2021 Jul 15;404(2):112634
Asiatic acid attenuates diabetic retinopathy through TLR4/MyD88/NF-κB p65 mediated modulation of microglia polarization.
Fang M, Wan W, Li Q, Wan W, Long Y, Liu H, Yang X
Life sciences 2021 Jul 15;277:119567
Life sciences 2021 Jul 15;277:119567
Chlamydia trachomatis Pgp3 protein regulates oxidative stress via activation of the Nrf2/NQO1 signal pathway.
Shu M, Lei W, Su S, Wen Y, Luo F, Zhao L, Chen L, Lu C, Zhou Z, Li Z
Life sciences 2021 Jul 15;277:119502
Life sciences 2021 Jul 15;277:119502
The mechanisms of action of WeiChang'An Pill (WCAP) treat diarrhoea-predominant irritable bowel syndrome (IBS-D) using network pharmacology approach and in vivo studies.
Chen Y, Chu F, Lin J, Su Z, Liao M, Li T, Li Y, Johnson N, Zheng H, Ding X
Journal of ethnopharmacology 2021 Jul 15;275:114119
Journal of ethnopharmacology 2021 Jul 15;275:114119
Proteomics analysis in the kidney of mice following oral feeding Realgar.
Zhang S, Li C, Feng T, Cao S, Zhou H, Li L, Hu Q, Mao X, Ji S
Journal of ethnopharmacology 2021 Jul 15;275:114118
Journal of ethnopharmacology 2021 Jul 15;275:114118
Identification and validation of an immune-related prognostic signature and key gene in papillary thyroid carcinoma.
Qin R, Li C, Wang X, Zhong Z, Sun C
Cancer cell international 2021 Jul 15;21(1):378
Cancer cell international 2021 Jul 15;21(1):378
Nonstructural Protein NSs Hampers Cellular Antiviral Response through LSm14A during Severe Fever with Thrombocytopenia Syndrome Virus Infection.
Zhang L, Fu Y, Zhang R, Guan Y, Jiang N, Zheng N, Wu Z
Journal of immunology (Baltimore, Md. : 1950) 2021 Jul 15;207(2):590-601
Journal of immunology (Baltimore, Md. : 1950) 2021 Jul 15;207(2):590-601
Role of IL-6-IL-27 Complex in Host Antiviral Immune Response.
Zuo Q, Cheng Z, Zhang G, Xia Y, Xu G, Cao W, Yang X, Fu Y, He R, Fang P, Guo Y, Nie L, Huang Y, Liu L, Zhan J, Liu S, Zhu Y
Journal of immunology (Baltimore, Md. : 1950) 2021 Jul 15;207(2):577-589
Journal of immunology (Baltimore, Md. : 1950) 2021 Jul 15;207(2):577-589
Protective effects and mechanisms of high-dose vitamin C on sepsis-associated cognitive impairment in rats.
Zhang N, Zhao W, Hu ZJ, Ge SM, Huo Y, Liu LX, Gao BL
Scientific reports 2021 Jul 15;11(1):14511
Scientific reports 2021 Jul 15;11(1):14511
Ubiquitin-specific protease 15 contributes to gastric cancer progression by regulating the Wnt/β-catenin signaling pathway.
Zhong M, Zhou L, Fang Z, Yao YY, Zou JP, Xiong JP, Xiang XJ, Deng J
World journal of gastroenterology 2021 Jul 14;27(26):4221-4235
World journal of gastroenterology 2021 Jul 14;27(26):4221-4235
LncRNA PCGEM1 induces proliferation and migration in non-small cell lung cancer cells through modulating the miR-590-3p/SOX11 axis.
Wen H, Feng H, Ma Q, Liang C
BMC pulmonary medicine 2021 Jul 14;21(1):234
BMC pulmonary medicine 2021 Jul 14;21(1):234
Cyclophilin A Inhibits Human Respiratory Syncytial Virus (RSV) Replication by Binding to RSV-N through Its PPIase Activity.
Liang W, Zhang Y, Li M, Al-Shaebi F, Li J, Zhang J, Wei L
Journal of virology 2021 Jul 12;95(15):e0056321
Journal of virology 2021 Jul 12;95(15):e0056321
S-Allylmercapto-N-acetylcysteine ameliorates elastase-induced chronic obstructive pulmonary disease in mice via regulating autophagy.
Zheng D, Wang J, Li G, An L, Qu Y, Zhang Q, Ye W, Zhao X, Zhao Z
Biochemical and biophysical research communications 2021 Jul 12;562:83-88
Biochemical and biophysical research communications 2021 Jul 12;562:83-88
YTHDF2 facilitates UBXN1 mRNA decay by recognizing METTL3-mediated m(6)A modification to activate NF-κB and promote the malignant progression of glioma.
Chai RC, Chang YZ, Chang X, Pang B, An SY, Zhang KN, Chang YH, Jiang T, Wang YZ
Journal of hematology & oncology 2021 Jul 10;14(1):109
Journal of hematology & oncology 2021 Jul 10;14(1):109
Repression of the AURKA-CXCL5 axis induces autophagic cell death and promotes radiosensitivity in non-small-cell lung cancer.
Wang J, Hu T, Wang Q, Chen R, Xie Y, Chang H, Cheng J
Cancer letters 2021 Jul 1;509:89-104
Cancer letters 2021 Jul 1;509:89-104
Epitranscriptomic addition of m(6)A regulates HIV-1 RNA stability and alternative splicing.
Tsai K, Bogerd HP, Kennedy EM, Emery A, Swanstrom R, Cullen BR
Genes & development 2021 Jul 1;35(13-14):992-1004
Genes & development 2021 Jul 1;35(13-14):992-1004
p55PIK deficiency and its NH(2)-terminal derivative inhibit inflammation and emphysema in COPD mouse model.
Wang T, Du X, Wang Z, Gu Y, Huang Q, Wu J, Zhan Y, Chen J, Xiao C, Xie J
American journal of physiology. Lung cellular and molecular physiology 2021 Jul 1;321(1):L159-L173
American journal of physiology. Lung cellular and molecular physiology 2021 Jul 1;321(1):L159-L173
GALNT2 promotes cell proliferation, migration, and invasion by activating the Notch/Hes1-PTEN-PI3K/Akt signaling pathway in lung adenocarcinoma.
Wang W, Sun R, Zeng L, Chen Y, Zhang N, Cao S, Deng S, Meng X, Yang S
Life sciences 2021 Jul 1;276:119439
Life sciences 2021 Jul 1;276:119439
IL37 overexpression inhibits autophagy and apoptosis induced by hepatic ischemia reperfusion injury via modulating AMPK/mTOR/ULLK1 signalling pathways.
Chen QS, Shen A, Dai JW, Li TT, Huang WF, Shi K, Deng Y, Pan L, Wei XF, Wu ZJ
Life sciences 2021 Jul 1;276:119424
Life sciences 2021 Jul 1;276:119424
Seneca Valley Virus 3C Protease Induces Pyroptosis by Directly Cleaving Porcine Gasdermin D.
Wen W, Li X, Wang H, Zhao Q, Yin M, Liu W, Chen H, Qian P
Journal of immunology (Baltimore, Md. : 1950) 2021 Jul 1;207(1):189-199
Journal of immunology (Baltimore, Md. : 1950) 2021 Jul 1;207(1):189-199
SUMO proteases SENP3 and SENP5 spatiotemporally regulate the kinase activity of Aurora A.
Yu B, Lin Q, Huang C, Zhang B, Wang Y, Jiang Q, Zhang C, Yi J
Journal of cell science 2021 Jul 1;134(13)
Journal of cell science 2021 Jul 1;134(13)
Long noncoding RNA BS-DRL1 modulates the DNA damage response and genome stability by interacting with HMGB1 in neurons.
Lou MM, Tang XQ, Wang GM, He J, Luo F, Guan MF, Wang F, Zou H, Wang JY, Zhang Q, Xu MJ, Shi QL, Shen LB, Ma GM, Wu Y, Zhang YY, Liang AB, Wang TH, Xiong LL, Wang J, Xu J, Wang WY
Nature communications 2021 Jul 1;12(1):4075
Nature communications 2021 Jul 1;12(1):4075
Toll-like receptor-2 gene knockout results in neurobehavioral dysfunctions and multiple brain structural and functional abnormalities in mice.
Hu Y, Sun X, Wang S, Zhou C, Lin L, Ding X, Han J, Zhou Y, Jin G, Wang Y, Zhang W, Shi H, Zhang Z, Yang X, Hua F
Brain, behavior, and immunity 2021 Jan;91:257-266
Brain, behavior, and immunity 2021 Jan;91:257-266
Hepatocyte growth factor mediates a novel form of hepatic stem/progenitor cell-induced tolerance in a rat xenogeneic liver rejection model.
Chen Q, You Y, Zhang Y, Zhang H, Bai L
International immunopharmacology 2021 Jan;90:107180
International immunopharmacology 2021 Jan;90:107180
MicroRNA-124-3p affects myogenic differentiation of adipose-derived stem cells by targeting Caveolin-1 during pelvic floor dysfunction in Sprague Dawley rats.
Chen H, Li Z, Lin M, Lv X, Wang J, Wei Q, Zhang Z, Li L
Annals of translational medicine 2021 Jan;9(2):161
Annals of translational medicine 2021 Jan;9(2):161
Repressing PDCD4 activates JNK/ABCG2 pathway to induce chemoresistance to fluorouracil in colorectal cancer cells.
Hu L, Liang Y, Wu K, Wang C, Zhang T, Peng R, Zou F
Annals of translational medicine 2021 Jan;9(2):114
Annals of translational medicine 2021 Jan;9(2):114
RNA-binding protein QKI suppresses breast cancer via RASA1/MAPK signaling pathway.
Cao Y, Chu C, Li X, Gu S, Zou Q, Jin Y
Annals of translational medicine 2021 Jan;9(2):104
Annals of translational medicine 2021 Jan;9(2):104
The Beneficial Role of Sunitinib in Tumor Immune Surveillance by Regulating Tumor PD-L1.
Li H, Kuang X, Liang L, Ye Y, Zhang Y, Li J, Ma F, Tao J, Lei G, Zhao S, Su J, Yang N, Peng C, Xu X, Hung MC, Han L, Liu H, Liu J, Chen X
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2021 Jan;8(2):2001596
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2021 Jan;8(2):2001596
Preventive effect of dioscin against monosodium urate-mediated gouty arthritis through inhibiting inflammasome NLRP3 and TLR4/NF-κB signaling pathway activation: an in vivo and in vitro study.
Han J, Shi G, Li W, Xie Y, Li F, Jiang D
Journal of natural medicines 2021 Jan;75(1):37-47
Journal of natural medicines 2021 Jan;75(1):37-47
ETV5 Regulates Hepatic Fatty Acid Metabolism Through PPAR Signaling Pathway.
Mao Z, Feng M, Li Z, Zhou M, Xu L, Pan K, Wang S, Su W, Zhang W
Diabetes 2021 Jan;70(1):214-226
Diabetes 2021 Jan;70(1):214-226
TBC1D3 promotes neural progenitor proliferation by suppressing the histone methyltransferase G9a.
Hou QQ, Xiao Q, Sun XY, Ju XC, Luo ZG
Science advances 2021 Jan;7(3)
Science advances 2021 Jan;7(3)
MicroRNA-489-3p Represses Hepatic Stellate Cells Activation by Negatively Regulating the JAG1/Notch3 Signaling Pathway.
Li J, Dong S, Ye M, Peng G, Luo J, Wang C, Wang J, Zhao Q, Chang Y, Wang H
Digestive diseases and sciences 2021 Jan;66(1):143-150
Digestive diseases and sciences 2021 Jan;66(1):143-150
FIGNL1 promotes non‑small cell lung cancer cell proliferation.
Li M, Rui Y, Peng W, Hu J, Jiang A, Yang Z, Huang L
International journal of oncology 2021 Jan;58(1):83-99
International journal of oncology 2021 Jan;58(1):83-99
Parthenolide inhibits the tumor characteristics of renal cell carcinoma.
Liu D, Han Y, Liu L, Ren X, Zhang H, Fan S, Qin T, Li L
International journal of oncology 2021 Jan;58(1):100-110
International journal of oncology 2021 Jan;58(1):100-110
Dysfunction of Shh signaling activates autophagy to inhibit trophoblast motility in recurrent miscarriage.
Pan Y, Yan L, Chen Q, Wei C, Dai Y, Tong X, Zhu H, Lu M, Zhang Y, Jin X, Zhang T, Lin X, Zhou F, Zhang S
Experimental & molecular medicine 2021 Jan;53(1):52-66
Experimental & molecular medicine 2021 Jan;53(1):52-66
DNA methylation of Hugl-2 is a prognostic biomarker in kidney renal clear cell carcinoma.
Miao Y, Cao F, Li P, Liu P
Clinical and experimental pharmacology & physiology 2021 Jan;48(1):44-53
Clinical and experimental pharmacology & physiology 2021 Jan;48(1):44-53
Prostaglandin E2 serves a dual role in regulating the migration of dendritic cells.
Diao G, Huang J, Zheng X, Sun X, Tian M, Han J, Guo J
International journal of molecular medicine 2021 Jan;47(1):207-218
International journal of molecular medicine 2021 Jan;47(1):207-218
Avasimibe exerts anticancer effects on human glioblastoma cells via inducing cell apoptosis and cell cycle arrest.
Liu JY, Fu WQ, Zheng XJ, Li W, Ren LW, Wang JH, Yang C, Du GH
Acta pharmacologica Sinica 2021 Jan;42(1):97-107
Acta pharmacologica Sinica 2021 Jan;42(1):97-107
UHRF1 Knockdown Attenuates Cell Growth, Migration, and Invasion in Cutaneous Squamous Cell Carcinoma.
Li Q, Chu Z, Geng S
Cancer investigation 2021 Jan;39(1):84-97
Cancer investigation 2021 Jan;39(1):84-97
Flavonoid compound breviscapine suppresses human osteosarcoma Saos-2 progression property and induces apoptosis by regulating mitochondria-dependent pathway.
Wang Z, Li H, Yan J, Liu Y
Journal of biochemical and molecular toxicology 2021 Jan;35(1):e22633
Journal of biochemical and molecular toxicology 2021 Jan;35(1):e22633
Nucleolin regulates 14-3-3ζ mRNA and promotes cofilin phosphorylation to induce tunneling nanotube formation.
Dagar S, Pushpa K, Pathak D, Samaddar S, Saxena A, Banerjee S, Mylavarapu SVS
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 Jan;35(1):e21199
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 Jan;35(1):e21199
Mefunidone ameliorates diabetic kidney disease in STZ and db/db mice.
Jiang Y, Xie F, Lv X, Wang S, Liao X, Yu Y, Dai Q, Zhang Y, Meng J, Hu G, Peng Z, Tao L
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 Jan;35(1):e21198
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 Jan;35(1):e21198
Rapid antidepressant-like effect of Fructus Aurantii depends on cAMP-response element binding protein/Brain-derived neurotrophic facto by mediating synaptic transmission.
Wu L, Zhang T, Chen K, Lu C, Liu XF, Zhou JL, Huang YK, Yan H, Chen Y, Zhang CJ, Li JF, Shi SQ, Ren P, Huang X
Phytotherapy research : PTR 2021 Jan;35(1):404-414
Phytotherapy research : PTR 2021 Jan;35(1):404-414
Effects of Y Box Binding Protein-1 in Progression and Prognosis of Cholangiocarcinoma.
Chen Y, Jiang P, Tian F, Chen G, Peng T, Deng X, Li Z, Huang D, Zhu J, Zhen P, Xie C, Wang S
Journal of investigative surgery : the official journal of the Academy of Surgical Research 2021 Jan;34(1):55-63
Journal of investigative surgery : the official journal of the Academy of Surgical Research 2021 Jan;34(1):55-63
Long noncoding RNA LINC00460 promotes the progression of cervical cancer via regulation of the miR-361-3p/Gli1 axis.
Li F, Zhu W, Wang Z
Human cell 2021 Jan;34(1):229-237
Human cell 2021 Jan;34(1):229-237
Long noncoding RNA TSLNC8 enhances pancreatic cancer aggressiveness by regulating CTNNB1 expression via association with HuR.
Chai W, Liu R, Li F, Zhang Z, Lei B
Human cell 2021 Jan;34(1):165-176
Human cell 2021 Jan;34(1):165-176
Hemizygous deletion of Tbk1 worsens neuromuscular junction pathology in TDP-43(G298S) transgenic mice.
Sieverding K, Ulmer J, Bruno C, Satoh T, Tsao W, Freischmidt A, Akira S, Wong PC, Ludolph AC, Danzer KM, Lobsiger CS, Brenner D, Weishaupt JH
Experimental neurology 2021 Jan;335:113496
Experimental neurology 2021 Jan;335:113496
MiR-19b-3p accelerates bone loss after spinal cord injury by suppressing osteogenesis via regulating PTEN/Akt/mTOR signalling.
Liu D, Wang B, Qiu M, Huang Y
Journal of cellular and molecular medicine 2021 Jan;25(2):990-1000
Journal of cellular and molecular medicine 2021 Jan;25(2):990-1000
Maltol prevents the progression of osteoarthritis by targeting PI3K/Akt/NF-κB pathway: In vitro and in vivo studies.
Lu H, Fu C, Kong S, Wang X, Sun L, Lin Z, Luo P, Jin H
Journal of cellular and molecular medicine 2021 Jan;25(1):499-509
Journal of cellular and molecular medicine 2021 Jan;25(1):499-509
Mixed-lineage leukaemia 1 contributes to endometrial stromal cells progesterone responsiveness during decidualization.
Xiong Y, Wang Y, Ma L, Zhang Y, Qu X, Huang L, Wen X, Liu H, Zhang M, Zhang Y
Journal of cellular and molecular medicine 2021 Jan;25(1):297-308
Journal of cellular and molecular medicine 2021 Jan;25(1):297-308
Blocking VRK2 suppresses pulmonary adenocarcinoma progression via ERK1/2/AKT signal pathway by targeting miR-145-5p.
Mu Y, Liu WJ, Bie LY, Mu XQ, Zhao YQ
European review for medical and pharmacological sciences 2021 Jan;25(1):145-153
European review for medical and pharmacological sciences 2021 Jan;25(1):145-153
Treatment of keloids through Runx2 siRNA‑induced inhibition of the PI3K/AKT signaling pathway.
Lv W, Wu M, Ren Y, Luo X, Hu W, Zhang Q, Wu Y
Molecular medicine reports 2021 Jan;23(1)
Molecular medicine reports 2021 Jan;23(1)
Protection against Dextran Sulfate Sodium-Induced Ulcerative Colitis in Mice by Neferine, A Natural Product from Nelumbo nucifera Gaertn.
Min X, Guo Y, Zhou Y, Chen X
Cell journal 2021 Jan;22(4):523-531
Cell journal 2021 Jan;22(4):523-531
Effect of HMGB1 on monocyte immune function in respiratory syncytial virus bronchiolitis.
Niu M, Jiang Z, Xin X, Zhu J, Yang J, Diao M, Qi G, Qi B
Experimental and therapeutic medicine 2021 Jan;21(1):75
Experimental and therapeutic medicine 2021 Jan;21(1):75
miR-155-5p regulates macrophage M1 polarization and apoptosis in the synovial fluid of patients with knee osteoarthritis.
Li GS, Cui L, Wang GD
Experimental and therapeutic medicine 2021 Jan;21(1):68
Experimental and therapeutic medicine 2021 Jan;21(1):68
Contribution of DNA methyltransferases to spared nerve injury induced depression partially through epigenetically repressing Bdnf in hippocampus: Reversal by ketamine.
Liu R, Wu XM, He X, Wang RZ, Yin XY, Zhou F, Ji MH, Shen JC
Pharmacology, biochemistry, and behavior 2021 Jan;200:173079
Pharmacology, biochemistry, and behavior 2021 Jan;200:173079
Suppressed nuclear envelope proteins activate autophagy of vascular smooth muscle cells during cyclic stretch application.
Li HP, Liu JT, Chen YX, Wang WB, Han Y, Yao QP, Qi YX
Biochimica et biophysica acta. Molecular cell research 2021 Jan;1868(1):118855
Biochimica et biophysica acta. Molecular cell research 2021 Jan;1868(1):118855
Inhibition of proliferation-linked signaling cascades with atractylenolide I reduces myofibroblastic phenotype and renal fibrosis.
Guo Y, Xiao Y, Zhu H, Guo H, Zhou Y, Shentu Y, Zheng C, Chen C, Bai Y
Biochemical pharmacology 2021 Jan;183:114344
Biochemical pharmacology 2021 Jan;183:114344
P-glycoprotein deficiency enhances metabolic activation of and platelet response to clopidogrel through marked up-regulation of Cyp3a11 in mice: Direct evidence for the interplay between P-glycoprotein and Cyp3a.
Ji JZ, Li YF, Jiang LP, Tai T, Ge PX, Mi QY, Zhu T, Xie HG
Biochemical pharmacology 2021 Jan;183:114313
Biochemical pharmacology 2021 Jan;183:114313
NCBP3/SNHG6 inhibits GBX2 transcription in a histone modification manner to facilitate the malignant biological behaviour of glioma cells.
Li X, Zhang F, Ma J, Ruan X, Liu X, Zheng J, Liu Y, Cao S, Shen S, Shao L, Cai H, Li Z, Xue Y
RNA biology 2021 Jan;18(1):47-63
RNA biology 2021 Jan;18(1):47-63
Targeted inhibition of Rev-erb-α/β limits ferroptosis to ameliorate folic acid-induced acute kidney injury.
Guo L, Zhang T, Wang F, Chen X, Xu H, Zhou C, Chen M, Yu F, Wang S, Yang D, Wu B
British journal of pharmacology 2021 Jan;178(2):328-345
British journal of pharmacology 2021 Jan;178(2):328-345
Inhibition of ferroptosis by up-regulating Nrf2 delayed the progression of diabetic nephropathy.
Li S, Zheng L, Zhang J, Liu X, Wu Z
Free radical biology & medicine 2021 Jan;162:435-449
Free radical biology & medicine 2021 Jan;162:435-449
The inhibition of colorectal cancer growth by the natural product macrocarpal I.
Qi L, Zhang Y, Zhang W, Wang Y, Han Y, Ding Y
Free radical biology & medicine 2021 Jan;162:383-391
Free radical biology & medicine 2021 Jan;162:383-391
HSF1 functions as a key defender against palmitic acid-induced ferroptosis in cardiomyocytes.
Wang N, Ma H, Li J, Meng C, Zou J, Wang H, Liu K, Liu M, Xiao X, Zhang H, Wang K
Journal of molecular and cellular cardiology 2021 Jan;150:65-76
Journal of molecular and cellular cardiology 2021 Jan;150:65-76
Exosome-mediated delivery of antisense oligonucleotides targeting α-synuclein ameliorates the pathology in a mouse model of Parkinson's disease.
Yang J, Luo S, Zhang J, Yu T, Fu Z, Zheng Y, Xu X, Liu C, Fan M, Zhang Z
Neurobiology of disease 2021 Jan;148:105218
Neurobiology of disease 2021 Jan;148:105218
Elevated ZBTB7A expression in the tumor invasive front correlates with more tumor budding formation in gastric adenocarcinoma.
Sun Y, He J, Shi DB, Zhang H, Chen X, Xing AY, Gao P
Journal of cancer research and clinical oncology 2021 Jan;147(1):105-115
Journal of cancer research and clinical oncology 2021 Jan;147(1):105-115
A SMOC2 variant inhibits BMP signaling by competitively binding to BMPR1B and causes growth plate defects.
Long F, Shi H, Li P, Guo S, Ma Y, Wei S, Li Y, Gao F, Gao S, Wang M, Duan R, Wang X, Yang K, Sun W, Li X, Li J, Liu Q
Bone 2021 Jan;142:115686
Bone 2021 Jan;142:115686
Melatonin increases the chemosensitivity of diffuse large B-cell lymphoma cells to epirubicin by inhibiting P-glycoprotein expression via the NF-κB pathway.
Liu K, Song J, Yan Y, Zou K, Che Y, Wang B, Li Z, Yu W, Guo W, Zou L, Deng W, Sun X
Translational oncology 2021 Jan;14(1):100876
Translational oncology 2021 Jan;14(1):100876
miRNA-146a-5p mitigates stress-induced premature senescence of D-galactose-induced primary thymic stromal cells.
Du H, Wang Y, Liu X, Wang S, Wu S, Yuan Z, Zhu X
Cytokine 2021 Jan;137:155314
Cytokine 2021 Jan;137:155314
CLDN10 associated with immune infiltration is a novel prognostic biomarker for clear cell renal cell carcinoma.
Yang W, Li L, Zhang K, Ma K, Gong Y, Zhou J, Gong K
Epigenomics 2021 Jan;13(1):31-45
Epigenomics 2021 Jan;13(1):31-45
Hyperglycemia-reduced NAD(+) biosynthesis impairs corneal epithelial wound healing in diabetic mice.
Li Y, Li J, Zhao C, Yang L, Qi X, Wang X, Zhou Q, Shi W
Metabolism: clinical and experimental 2021 Jan;114:154402
Metabolism: clinical and experimental 2021 Jan;114:154402
NNT-induced tumor cell "slimming" reverses the pro-carcinogenesis effect of HIF2a in tumors.
Xiong Z, Xiong W, Xiao W, Yuan C, Shi J, Huang Y, Wang C, Meng X, Chen Z, Yang H, Chen K, Zhang X
Clinical and translational medicine 2021 Jan;11(1):e264
Clinical and translational medicine 2021 Jan;11(1):e264
Disrupted glucose homeostasis and skeletal-muscle-specific glucose uptake in an exocyst knockout mouse model.
Fujimoto BA, Young M, Nakamura N, Ha H, Carter L, Pitts MW, Torres D, Noh HL, Suk S, Kim JK, Polgar N
The Journal of biological chemistry 2021 Jan-Jun;296:100482
The Journal of biological chemistry 2021 Jan-Jun;296:100482
Determining the quantitative relationship between glycolysis and GAPDH in cancer cells exhibiting the Warburg effect.
Zhu X, Jin C, Pan Q, Hu X
The Journal of biological chemistry 2021 Jan-Jun;296:100369
The Journal of biological chemistry 2021 Jan-Jun;296:100369
Salvianolic acid B blocks hepatic stellate cell activation via FGF19/FGFR4 signaling.
Tian S, Chen M, Wang B, Han Y, Shang H, Chen J
Annals of hepatology 2021 Jan-Feb;20:100259
Annals of hepatology 2021 Jan-Feb;20:100259
Melatonin ameliorates hepatic steatosis by inhibiting NLRP3 inflammasome in db/db mice.
Yu Y, Chen D, Zhao Y, Zhu J, Dong X
International journal of immunopathology and pharmacology 2021 Jan-Dec;35:20587384211036819
International journal of immunopathology and pharmacology 2021 Jan-Dec;35:20587384211036819
Valproic acid Suppresses Breast Cancer Cell Growth Through Triggering Pyruvate Kinase M2 Isoform Mediated Warburg Effect.
Li Z, Yang L, Zhang S, Song J, Sun H, Shan C, Wang D, Liu S
Cell transplantation 2021 Jan-Dec;30:9636897211027524
Cell transplantation 2021 Jan-Dec;30:9636897211027524
Electroacupuncture Attenuates Morphine Tolerance in Rats with Bone Cancer Pain by Inhibiting PI3K/Akt/JNK1/2 Signaling Pathway in the Spinal Dorsal Horn.
Jiang B, Zhong X, Fang J, Zhang A, WangD W, Liang Y, Fang J, Chen F, Du J
Integrative cancer therapies 2021 Jan-Dec;20:1534735421995237
Integrative cancer therapies 2021 Jan-Dec;20:1534735421995237
Heparan sulfate 3-O-sulfotransferase 4 is genetically associated with herpes zoster and enhances varicella-zoster virus-mediated fusogenic activity.
Ohka S, Yamada S, Nishizawa D, Fukui Y, Arita H, Hanaoka K, Iseki M, Kato J, Ogawa S, Hiranuma A, Kasai S, Hasegawa J, Hayashida M, Fukushi S, Saijo M, Ikeda AK
Molecular pain 2021 Jan-Dec;17:17448069211052171
Molecular pain 2021 Jan-Dec;17:17448069211052171
Thermoresponsive GenisteinNLC-dexamethasone-moxifloxacin multi drug delivery system in lens capsule bag to prevent complications after cataract surgery.
Yan T, Ma Z, Liu J, Yin N, Lei S, Zhang X, Li X, Zhang Y, Kong J
Scientific reports 2021 Jan 8;11(1):181
Scientific reports 2021 Jan 8;11(1):181
Effects of ER-resident and secreted AGR2 on cell proliferation, migration, invasion, and survival in PANC-1 pancreatic cancer cells.
Hong X, Li ZX, Hou J, Zhang HY, Zhang CY, Zhang J, Sun H, Pang LH, Wang T, Deng ZH
BMC cancer 2021 Jan 7;21(1):33
BMC cancer 2021 Jan 7;21(1):33
Intraperitoneal injection of Desferal® alleviated the age-related bone loss and senescence of bone marrow stromal cells in rats.
Yi L, Ju Y, He Y, Yin X, Xu Y, Weng T
Stem cell research & therapy 2021 Jan 7;12(1):45
Stem cell research & therapy 2021 Jan 7;12(1):45
Indoleamine 2,3-dioxygenase 1 limits hepatic inflammatory cells recruitment and promotes bile duct ligation-induced liver fibrosis.
Mo C, Xie S, Liu B, Zhong W, Zeng T, Huang S, Lai Y, Deng G, Zhou C, Yan W, Chen Y, Huang S, Gao L, Lv Z
Cell death & disease 2021 Jan 7;12(1):16
Cell death & disease 2021 Jan 7;12(1):16
Rabies virus matrix protein targets host actin cytoskeleton: a protein-protein interaction analysis.
Zandi F, Khalaj V, Goshadrou F, Meyfour A, Gholami A, Enayati S, Mehranfar M, Rahmati S, Kheiri EV, Badie HG, Vaziri B
Pathogens and disease 2021 Jan 6;79(1)
Pathogens and disease 2021 Jan 6;79(1)
Lnc-GAN1 expression is associated with good survival and suppresses tumor progression by sponging mir-26a-5p to activate PTEN signaling in non-small cell lung cancer.
Wang RQ, Long XR, Zhou NN, Chen DN, Zhang MY, Wen ZS, Zhang LJ, He FZ, Zhou ZL, Mai SJ, Wang HY
Journal of experimental & clinical cancer research : CR 2021 Jan 6;40(1):9
Journal of experimental & clinical cancer research : CR 2021 Jan 6;40(1):9
MCCC2 promotes HCC development by supporting leucine oncogenic function.
Chen YY, Zhang XN, Xu CZ, Zhou DH, Chen J, Liu ZX, Sun Y, Huang W, Qu LS
Cancer cell international 2021 Jan 6;21(1):22
Cancer cell international 2021 Jan 6;21(1):22
Environmental noise stress disturbs commensal microbiota homeostasis and induces oxi-inflammmation and AD-like neuropathology through epithelial barrier disruption in the EOAD mouse model.
Chi H, Cao W, Zhang M, Su D, Yang H, Li Z, Li C, She X, Wang K, Gao X, Ma K, Zheng P, Li X, Cui B
Journal of neuroinflammation 2021 Jan 6;18(1):9
Journal of neuroinflammation 2021 Jan 6;18(1):9
miR-142 downregulation alleviates rat PTSD-like behaviors, reduces the level of inflammatory cytokine expression and apoptosis in hippocampus, and upregulates the expression of fragile X mental retardation protein.
Nie PY, Tong L, Li MD, Fu CH, Peng JB, Ji LL
Journal of neuroinflammation 2021 Jan 6;18(1):17
Journal of neuroinflammation 2021 Jan 6;18(1):17
Leptin Receptor (LEPR) promotes proliferation, migration, and invasion and inhibits apoptosis in hepatocellular carcinoma by regulating ANXA7.
Huang H, Zhang J, Ling F, Huang Y, Yang M, Zhang Y, Wei Y, Zhang Q, Wang H, Song L, Wu Y, Yang J, Tang J
Cancer cell international 2021 Jan 4;21(1):4
Cancer cell international 2021 Jan 4;21(1):4
Tumor genotype dictates radiosensitization after Atm deletion in primary brainstem glioma models.
Deland K, Starr BF, Mercer JS, Byemerwa J, Crabtree DM, Williams NT, Luo L, Ma Y, Chen M, Becher OJ, Kirsch DG
The Journal of clinical investigation 2021 Jan 4;131(1)
The Journal of clinical investigation 2021 Jan 4;131(1)
Improvement of obesity-associated disorders by a small-molecule drug targeting mitochondria of adipose tissue macrophages.
Wang Y, Tang B, Long L, Luo P, Xiang W, Li X, Wang H, Jiang Q, Tan X, Luo S, Li H, Wang Z, Chen Z, Leng Y, Jiang Z, Wang Y, Ma L, Wang R, Zeng C, Liu Z, Wang Y, Miao H, Shi C
Nature communications 2021 Jan 4;12(1):102
Nature communications 2021 Jan 4;12(1):102
Interplay of opposing fate choices stalls oncogenic growth in murine skin epithelium.
Sandoval M, Ying Z, Beronja S
eLife 2021 Jan 4;10
eLife 2021 Jan 4;10
Neuroprotective effects of SOX5 against ischemic stroke by regulating VEGF/PI3K/AKT pathway.
Zhang W, Wu Y, Chen H, Yu D, Zhao J, Chen J
Gene 2021 Jan 30;767:145148
Gene 2021 Jan 30;767:145148
Discovery and proteomics analysis of effective compounds in Valeriana jatamansi jones for the treatment of anxiety.
Wang SN, Yao ZW, Zhao CB, Ding YS, Jing-Luo, Bian LH, Li QY, Wang XM, Shi JL, Guo JY, Wang CG
Journal of ethnopharmacology 2021 Jan 30;265:113452
Journal of ethnopharmacology 2021 Jan 30;265:113452
Angiogenesis is promoted by exosomal DPP4 derived from 5-fluorouracil-resistant colon cancer cells.
Zheng X, Liu J, Li X, Tian R, Shang K, Dong X, Cao B
Cancer letters 2021 Jan 28;497:190-201
Cancer letters 2021 Jan 28;497:190-201
LncRNA H19-Derived miR-675-5p Accelerates the Invasion of Extravillous Trophoblast Cells by Inhibiting GATA2 and Subsequently Activating Matrix Metalloproteinases.
Ogoyama M, Ohkuchi A, Takahashi H, Zhao D, Matsubara S, Takizawa T
International journal of molecular sciences 2021 Jan 27;22(3)
International journal of molecular sciences 2021 Jan 27;22(3)
Connective tissue growth factor promotes chemotaxis of preosteoblasts through integrin α5 and Ras during tensile force-induced intramembranous osteogenesis.
Jiang W, Takeshita N, Maeda T, Sogi C, Oyanagi T, Kimura S, Yoshida M, Sasaki K, Ito A, Takano-Yamamoto T
Scientific reports 2021 Jan 27;11(1):2368
Scientific reports 2021 Jan 27;11(1):2368
Echinatin effectively protects against NLRP3 inflammasome-driven diseases by targeting HSP90.
Xu G, Fu S, Zhan X, Wang Z, Zhang P, Shi W, Qin N, Chen Y, Wang C, Niu M, Guo Y, Wang J, Bai Z, Xiao X
JCI insight 2021 Jan 25;6(2)
JCI insight 2021 Jan 25;6(2)
Vitamin D alleviates liver fibrosis by inhibiting histidine-rich calcium binding protein (HRC).
Lu W, Li X, Liu N, Zhang Y, Li Y, Pan Y, Yang J, Liu Z, Kong J
Chemico-biological interactions 2021 Jan 25;334:109355
Chemico-biological interactions 2021 Jan 25;334:109355
Immunophenotype of Gastric Tumors Unveils a Pleiotropic Role of Regulatory T Cells in Tumor Development.
Rocha S, Basto AP, Ijsselsteijn ME, Teles SP, Azevedo MM, Gonçalves G, Gullo I, Almeida GM, Maqueda JJ, Oliveira MI, Carneiro F, Barata JT, Graça L, de Miranda NFCC, Carvalho J, Oliveira C
Cancers 2021 Jan 23;13(3)
Cancers 2021 Jan 23;13(3)
Long-read transcriptome sequencing reveals abundant promoter diversity in distinct molecular subtypes of gastric cancer.
Huang KK, Huang J, Wu JKL, Lee M, Tay ST, Kumar V, Ramnarayanan K, Padmanabhan N, Xu C, Tan ALK, Chan C, Kappei D, Göke J, Tan P
Genome biology 2021 Jan 22;22(1):44
Genome biology 2021 Jan 22;22(1):44
Discovery of a Functional Covalent Ligand Targeting an Intrinsically Disordered Cysteine within MYC.
Boike L, Cioffi AG, Majewski FC, Co J, Henning NJ, Jones MD, Liu G, McKenna JM, Tallarico JA, Schirle M, Nomura DK
Cell chemical biology 2021 Jan 21;28(1):4-13.e17
Cell chemical biology 2021 Jan 21;28(1):4-13.e17
Human umbilical cord mesenchymal stem cell-derived exosomal miR-146a-5p reduces microglial-mediated neuroinflammation via suppression of the IRAK1/TRAF6 signaling pathway after ischemic stroke.
Zhang Z, Zou X, Zhang R, Xie Y, Feng Z, Li F, Han J, Sun H, Ouyang Q, Hua S, Lv B, Hua T, Liu Z, Cai Y, Zou Y, Tang Y, Jiang X
Aging 2021 Jan 21;13(2):3060-3079
Aging 2021 Jan 21;13(2):3060-3079
SERCA2a ameliorates cardiomyocyte T-tubule remodeling via the calpain/JPH2 pathway to improve cardiac function in myocardial ischemia/reperfusion mice.
Wang S, Zhou Y, Luo Y, Kan R, Chen J, Xuan H, Wang C, Chen J, Xu T, Li D
Scientific reports 2021 Jan 21;11(1):2037
Scientific reports 2021 Jan 21;11(1):2037
Identification of Cleavage Sites Proteolytically Processed by NS2B-NS3 Protease in Polyprotein of Japanese Encephalitis Virus.
Wahaab A, Liu K, Hameed M, Anwar MN, Kang L, Li C, Ma X, Wajid A, Yang Y, Khan UH, Wei J, Li B, Shao D, Qiu Y, Ma Z
Pathogens (Basel, Switzerland) 2021 Jan 21;10(2)
Pathogens (Basel, Switzerland) 2021 Jan 21;10(2)
An Autism-Associated Mutation Impairs Neuroligin-4 Glycosylation and Enhances Excitatory Synaptic Transmission in Human Neurons.
Cast TP, Boesch DJ, Smyth K, Shaw AE, Ghebrial M, Chanda S
The Journal of neuroscience : the official journal of the Society for Neuroscience 2021 Jan 20;41(3):392-407
The Journal of neuroscience : the official journal of the Society for Neuroscience 2021 Jan 20;41(3):392-407
Notoginsenoside R1 attenuates breast cancer progression by targeting CCND2 and YBX3.
Qin HL, Wang XJ, Yang BX, Du B, Yun XL
Chinese medical journal 2021 Jan 20;134(5):546-554
Chinese medical journal 2021 Jan 20;134(5):546-554
Adipose-derived stromal cells improve functional recovery after spinal cord injury through TGF-β1/Smad3/PLOD2 pathway activation.
Li F, Liu H, Zhang K, Xiao DJ, Wang C, Wang YS
Aging 2021 Jan 20;13(3):4370-4387
Aging 2021 Jan 20;13(3):4370-4387
The mitochondrial protein ERAL1 suppresses RNA virus infection by facilitating RIG-I-like receptor signaling.
Li S, Kuang M, Chen L, Li Y, Liu S, Du H, Cao L, You F
Cell reports 2021 Jan 19;34(3):108631
Cell reports 2021 Jan 19;34(3):108631
Development of DNA Vaccine Targeting E6 and E7 Proteins of Human Papillomavirus 16 (HPV16) and HPV18 for Immunotherapy in Combination with Recombinant Vaccinia Boost and PD-1 Antibody.
Peng S, Ferrall L, Gaillard S, Wang C, Chi WY, Huang CH, Roden RBS, Wu TC, Chang YN, Hung CF
mBio 2021 Jan 19;12(1)
mBio 2021 Jan 19;12(1)
Hsa_circ_0007456 regulates the natural killer cell-mediated cytotoxicity toward hepatocellular carcinoma via the miR-6852-3p/ICAM-1 axis.
Shi M, Li ZY, Zhang LM, Wu XY, Xiang SH, Wang YG, Zhang YQ
Cell death & disease 2021 Jan 18;12(1):94
Cell death & disease 2021 Jan 18;12(1):94
Human RECQL5 promotes metastasis and resistance to cisplatin in non-small cell lung cancer.
Xia HW, Zhang ZQ, Yuan J, Niu QL
Life sciences 2021 Jan 15;265:118768
Life sciences 2021 Jan 15;265:118768
MicroRNA-150 affects endoplasmic reticulum stress via MALAT1-miR-150 axis-mediated NF-κB pathway in LPS-challenged HUVECs and septic mice.
Liu L, Yan LN, Sui Z
Life sciences 2021 Jan 15;265:118744
Life sciences 2021 Jan 15;265:118744
Discovery of a novel small-molecule inhibitor of Fam20C that induces apoptosis and inhibits migration in triple negative breast cancer.
Zhao R, Fu L, Yuan Z, Liu Y, Zhang K, Chen Y, Wang L, Sun D, Chen L, Liu B, Zhang L
European journal of medicinal chemistry 2021 Jan 15;210:113088
European journal of medicinal chemistry 2021 Jan 15;210:113088
Atractylodis macrocephalae polysaccharides protect against DSS-induced intestinal injury through a novel lncRNA ITSN1-OT1.
Zong X, Xiao X, Kai L, Cheng Y, Fu J, Xu W, Wang Y, Zhao K, Jin M
International journal of biological macromolecules 2021 Jan 15;167:76-84
International journal of biological macromolecules 2021 Jan 15;167:76-84
Circ_0001438 participates in the pathogenesis of preeclampsia via the circ_0001438/miR-942/NLRP3 regulatory network.
Li X, Yang R, Xu Y, Zhang Y
Placenta 2021 Jan 15;104:40-50
Placenta 2021 Jan 15;104:40-50
Single cell transcriptomic analysis of human pluripotent stem cell chondrogenesis.
Wu CL, Dicks A, Steward N, Tang R, Katz DB, Choi YR, Guilak F
Nature communications 2021 Jan 13;12(1):362
Nature communications 2021 Jan 13;12(1):362
Functional constipation induces bladder overactivity associated with upregulations of Htr2 and Trpv2 pathways.
Iguchi N, Carrasco A Jr, Xie AX, Pineda RH, Malykhina AP, Wilcox DT
Scientific reports 2021 Jan 13;11(1):1149
Scientific reports 2021 Jan 13;11(1):1149
Genome-wide Screens Identify Lineage- and Tumor-Specific Genes Modulating MHC-I- and MHC-II-Restricted Immunosurveillance of Human Lymphomas.
Dersh D, Phelan JD, Gumina ME, Wang B, Arbuckle JH, Holly J, Kishton RJ, Markowitz TE, Seedhom MO, Fridlyand N, Wright GW, Huang DW, Ceribelli M, Thomas CJ, Lack JB, Restifo NP, Kristie TM, Staudt LM, Yewdell JW
Immunity 2021 Jan 12;54(1):116-131.e10
Immunity 2021 Jan 12;54(1):116-131.e10
miR-199b-5p enhances the proliferation of medullary thymic epithelial cells via regulating Wnt signaling by targeting Fzd6.
Wang X, Li Y, Gong B, Zhang K, Ma Y, Li Y
Acta biochimica et biophysica Sinica 2021 Jan 12;53(1):36-45
Acta biochimica et biophysica Sinica 2021 Jan 12;53(1):36-45
The DDX39B/FUT3/TGFβR-I axis promotes tumor metastasis and EMT in colorectal cancer.
He C, Li A, Lai Q, Ding J, Yan Q, Liu S, Li Q
Cell death & disease 2021 Jan 12;12(1):74
Cell death & disease 2021 Jan 12;12(1):74
Cellular and molecular landscape of mammalian sinoatrial node revealed by single-cell RNA sequencing.
Liang D, Xue J, Geng L, Zhou L, Lv B, Zeng Q, Xiong K, Zhou H, Xie D, Zhang F, Liu J, Liu Y, Li L, Yang J, Xue Z, Chen YH
Nature communications 2021 Jan 12;12(1):287
Nature communications 2021 Jan 12;12(1):287
Transcription elongation factor A-like 7, regulated by miR-758-3p inhibits the progression of melanoma through decreasing the expression levels of c-Myc and AKT1.
Liu X, Song X, Li H
Cancer cell international 2021 Jan 11;21(1):43
Cancer cell international 2021 Jan 11;21(1):43
Mtu1 defects are correlated with reduced osteogenic differentiation.
He Q, Zhao Q, Li Q, Pan R, Li X, Chen Y
Cell death & disease 2021 Jan 11;12(1):61
Cell death & disease 2021 Jan 11;12(1):61
Knockdown of CENPF inhibits the progression of lung adenocarcinoma mediated by ERβ2/5 pathway.
Hexiao T, Yuquan B, Lecai X, Yanhong W, Li S, Weidong H, Ming X, Xuefeng Z, Gaofeng P, Li Z, Minglin Z, Zheng T, Zetian Y, Xiao Z, Yi C, Lanuti M, Jinping Z
Aging 2021 Jan 10;13(2):2604-2625
Aging 2021 Jan 10;13(2):2604-2625
Tetrachlorobenzoquinone exhibits immunotoxicity by inducing neutrophil extracellular traps through a mechanism involving ROS-JNK-NOX2 positive feedback loop.
Lv X, Liu Z, Xu L, Song E, Song Y
Environmental pollution (Barking, Essex : 1987) 2021 Jan 1;268(Pt B):115921
Environmental pollution (Barking, Essex : 1987) 2021 Jan 1;268(Pt B):115921
Canstatin represses glioma growth by inhibiting formation of VM-like structures.
Ma Y, Wu T, Zhou H, He G, Li Y, Wang B, Guo Q, Chen B, Li W
Translational neuroscience 2021 Jan 1;12(1):309-319
Translational neuroscience 2021 Jan 1;12(1):309-319
SQSTM1/ p62 oligomerization contributes to Aβ-induced inhibition of Nrf2 signaling.
Guo C, Zhang Y, Nie Q, Cao D, Wang X, Wan X, Liu M, Cui J, Sun J, Bai Y, Li L
Neurobiology of aging 2021 Feb;98:10-20
Neurobiology of aging 2021 Feb;98:10-20
Kiaa0101 serves as a prognostic marker and promotes invasion by regulating p38/snail1 pathway in glioma.
Liu J, Gao L, Liao J, Yang J, Yuan F, Chen Q
Annals of translational medicine 2021 Feb;9(3):260
Annals of translational medicine 2021 Feb;9(3):260
Eldecalcitol induces apoptosis and autophagy in human osteosarcoma MG-63 cells by accumulating ROS to suppress the PI3K/Akt/mTOR signaling pathway.
Zhang C, Huang C, Yang P, Li C, Li M
Cellular signalling 2021 Feb;78:109841
Cellular signalling 2021 Feb;78:109841
Gastrin-17 induces gastric cancer cell epithelial-mesenchymal transition via the Wnt/β-catenin signaling pathway.
Li Y, Zhao Y, Li Y, Zhang X, Li C, Long N, Chen X, Bao L, Zhou J, Xie Y
Journal of physiology and biochemistry 2021 Feb;77(1):93-104
Journal of physiology and biochemistry 2021 Feb;77(1):93-104
RNA-binding protein HuR suppresses senescence through Atg7 mediated autophagy activation in diabetic intervertebral disc degeneration.
Shao Z, Ni L, Hu S, Xu T, Meftah Z, Yu Z, Tian N, Wu Y, Sun L, Wu A, Pan Z, Chen L, Gao W, Zhou Y, Zhang X, Wang X
Cell proliferation 2021 Feb;54(2):e12975
Cell proliferation 2021 Feb;54(2):e12975
Kcnh2 mediates FAK/AKT-FOXO3A pathway to attenuate sepsis-induced cardiac dysfunction.
Li Z, Meng Y, Liu C, Liu H, Cao W, Tong C, Lu M, Li L, Peng L
Cell proliferation 2021 Feb;54(2):e12962
Cell proliferation 2021 Feb;54(2):e12962
lncRNA NEAT1 ameliorates LPS‑induced inflammation in MG63 cells by activating autophagy and suppressing the NLRP3 inflammasome.
Dai W, Wang M, Wang P, Wen J, Wang J, Cha S, Xiao X, He Y, Shu R, Bai D
International journal of molecular medicine 2021 Feb;47(2):607-620
International journal of molecular medicine 2021 Feb;47(2):607-620
lncRNA FOXP4‑AS1 predicts poor prognosis and accelerates the progression of mantle cell lymphoma through the miR‑423‑5p/NACC1 pathway.
Tao HF, Shen JX, Hou ZW, Chen SY, Su YZ, Fang JL
Oncology reports 2021 Feb;45(2):469-480
Oncology reports 2021 Feb;45(2):469-480
Circular RNA circNFATC3 acts as a miR-9-5p sponge to promote cervical cancer development by upregulating SDC2.
Ma N, Li X, Wei H, Zhang H, Zhang S
Cellular oncology (Dordrecht, Netherlands) 2021 Feb;44(1):93-107
Cellular oncology (Dordrecht, Netherlands) 2021 Feb;44(1):93-107
OPA1 haploinsufficiency due to a novel splicing variant resulting in mitochondrial dysfunction without mitochondrial DNA depletion.
Sun C, Wu X, Bai HX, Wang C, Liu Z, Yang C, Lu Y, Jiang P
Ophthalmic genetics 2021 Feb;42(1):45-52
Ophthalmic genetics 2021 Feb;42(1):45-52
CRISPR/Cas9 screening identifies a kinetochore-microtubule dependent mechanism for Aurora-A inhibitor resistance in breast cancer.
Chen A, Wen S, Liu F, Zhang Z, Liu M, Wu Y, He B, Yan M, Kang T, Lam EW, Wang Z, Liu Q
Cancer communications (London, England) 2021 Feb;41(2):121-139
Cancer communications (London, England) 2021 Feb;41(2):121-139
PRMT1 enhances oncogenic arginine methylation of NONO in colorectal cancer.
Yin XK, Wang YL, Wang F, Feng WX, Bai SM, Zhao WW, Feng LL, Wei MB, Qin CL, Wang F, Chen ZL, Yi HJ, Huang Y, Xie PY, Kim T, Wang YN, Hou JW, Li CW, Liu Q, Fan XJ, Hung MC, Wan XB
Oncogene 2021 Feb;40(7):1375-1389
Oncogene 2021 Feb;40(7):1375-1389
miR-23a-3p regulated by LncRNA SNHG5 suppresses the chondrogenic differentiation of human adipose-derived stem cells via targeting SOX6/SOX5.
Yang Z, Ren Z, She R, Ao J, Wa Q, Sun Z, Li B, Tian X
Cell and tissue research 2021 Feb;383(2):723-733
Cell and tissue research 2021 Feb;383(2):723-733
MicroRNA-936/ERBB4/Akt axis exhibits anticancer properties of gastric cancer through inhibition of cell proliferation, migration, and invasion.
Liu S, Gong Y, Xu XD, Shen H, Gao S, Bao HD, Guo SB, Yu XF, Gong J
The Kaohsiung journal of medical sciences 2021 Feb;37(2):111-120
The Kaohsiung journal of medical sciences 2021 Feb;37(2):111-120
The Kv1.3 ion channel acts as a host factor restricting viral entry.
Lang Y, Li F, Liu Q, Xia Z, Ji Z, Hu J, Cheng Y, Gao M, Sun F, Shen B, Xie C, Yi W, Wu Y, Yao J, Cao Z
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 Feb;35(2):e20995
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 Feb;35(2):e20995
Rosmarinic acid exerts an antagonistic effect on nonalcoholic fatty liver disease by regulating the YAP1/TAZ-PPARγ/PGC-1α signaling pathway.
Luo C, Sun H, Peng J, Gao C, Bao L, Ji R, Zhang C, Zhu W, Jin Y
Phytotherapy research : PTR 2021 Feb;35(2):1010-1022
Phytotherapy research : PTR 2021 Feb;35(2):1010-1022
COPII mitigates ER stress by promoting formation of ER whorls.
Xu F, Du W, Zou Q, Wang Y, Zhang X, Xing X, Li Y, Zhang D, Wang H, Zhang W, Hu X, Liu X, Liu X, Zhang S, Yu J, Fang J, Li F, Zhou Y, Yue T, Mi N, Deng H, Zou P, Chen X, Yang X, Yu L
Cell research 2021 Feb;31(2):141-156
Cell research 2021 Feb;31(2):141-156
UBE2O targets Mxi1 for ubiquitination and degradation to promote lung cancer progression and radioresistance.
Huang Y, Yang X, Lu Y, Zhao Y, Meng R, Zhang S, Dong X, Xu S, Wu G
Cell death and differentiation 2021 Feb;28(2):671-684
Cell death and differentiation 2021 Feb;28(2):671-684
TDP-43 aggregation induced by oxidative stress causes global mitochondrial imbalance in ALS.
Zuo X, Zhou J, Li Y, Wu K, Chen Z, Luo Z, Zhang X, Liang Y, Esteban MA, Zhou Y, Fu XD
Nature structural & molecular biology 2021 Feb;28(2):132-142
Nature structural & molecular biology 2021 Feb;28(2):132-142
The interaction between lipocalin 2 and dipyridine ketone hydrazone dithiocarbamte may influence respective function in proliferation and metastasis-related gene expressions in HepG2 cell.
Li C, Li Y, Lou L, Han X, Wang H, Huang T, Li C
Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 2021 Feb;26(1):123-133
Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 2021 Feb;26(1):123-133
M2 macrophage-derived G-CSF promotes trophoblasts EMT, invasion and migration via activating PI3K/Akt/Erk1/2 pathway to mediate normal pregnancy.
Ding J, Yang C, Zhang Y, Wang J, Zhang S, Guo D, Yin T, Yang J
Journal of cellular and molecular medicine 2021 Feb;25(4):2136-2147
Journal of cellular and molecular medicine 2021 Feb;25(4):2136-2147
LINC01116 promotes proliferation and migration of endometrial stromal cells by targeting FOXP1 via sponging miR-9-5p in endometriosis.
Cui L, Chen S, Wang D, Yang Q
Journal of cellular and molecular medicine 2021 Feb;25(4):2000-2012
Journal of cellular and molecular medicine 2021 Feb;25(4):2000-2012
FoxM1 promotes Wnt/β-catenin pathway activation and renal fibrosis via transcriptionally regulating multi-Wnts expressions.
Xie H, Miao N, Xu D, Zhou Z, Ni J, Yin F, Wang Y, Cheng Q, Chen P, Li J, Zheng P, Zhou L, Liu J, Zhang W, Wang X, Lu L
Journal of cellular and molecular medicine 2021 Feb;25(4):1958-1971
Journal of cellular and molecular medicine 2021 Feb;25(4):1958-1971
AGGF1 inhibits the expression of inflammatory mediators and promotes angiogenesis in dental pulp cells.
Shen S, Shang L, Liu H, Liang Q, Liang W, Ge S
Clinical oral investigations 2021 Feb;25(2):581-592
Clinical oral investigations 2021 Feb;25(2):581-592
Ptk2b deletion improves mice folliculogenesis and fecundity via inhibiting follicle loss mediated by Erk pathway.
Cong Y, Wu H, Bian X, Xie Q, Lyu Q, Cui J, Suo L, Kuang Y
Journal of cellular physiology 2021 Feb;236(2):1043-1053
Journal of cellular physiology 2021 Feb;236(2):1043-1053
Molecular mechanism underlying miR‑130b‑Sp1 transcriptional regulation in LPS‑induced upregulation of MUC5AC in the bile duct epithelium.
Wu X, Yao C, Kong J, Tian Y, Fan Y, Zhang Z, Han J, Wu S
Molecular medicine reports 2021 Feb;23(2)
Molecular medicine reports 2021 Feb;23(2)
Knockdown of long non‑coding RNA ANRIL inhibits the proliferation and promotes the apoptosis of Burkitt lymphoma cells through the TGF‑β1 signaling pathway.
Mao S, Jin J, Li Z, Yang W
Molecular medicine reports 2021 Feb;23(2)
Molecular medicine reports 2021 Feb;23(2)
Matrix metalloproteinase 3 regulates angiotensin II‑induced myocardial fibrosis cell viability, migration and apoptosis.
Shu J, Gu Y, Jin L, Wang H
Molecular medicine reports 2021 Feb;23(2)
Molecular medicine reports 2021 Feb;23(2)
Benzidine promotes the stemness of bladder cancer stem cells via activation of the Sonic hedgehog pathway.
Wang D, Xie D, Bi L, Wang Y, Zou C, Chen L, Geng H, Qian W, Li Y, Sun H, Wang X, Lu Y, Yu D, Zhong C
Oncology letters 2021 Feb;21(2):146
Oncology letters 2021 Feb;21(2):146
Crosstalk between phosphorylation and ubiquitination is involved in high salt-induced WNK4 expression.
Zhao X, Lai G, Tu J, Liu S, Zhao Y
Experimental and therapeutic medicine 2021 Feb;21(2):133
Experimental and therapeutic medicine 2021 Feb;21(2):133
Dysregulation of phosphoproteins in hepatocellular carcinoma revealed via quantitative analysis of the phosphoproteome.
Liu Y, Zhao Q, Xu F, Wang K, Zhao Y, Chen H, He W, Wang W, Zhang J, Zhang J
Oncology letters 2021 Feb;21(2):117
Oncology letters 2021 Feb;21(2):117
Inhibition of autophagy aggravates molybdenum-induced mitochondrial dysfunction by aggravating oxidative stress in duck renal tubular epithelial cells.
Zhuang J, Nie G, Hu R, Wang C, Xing C, Li G, Hu G, Yang F, Zhang C
Ecotoxicology and environmental safety 2021 Feb;209:111771
Ecotoxicology and environmental safety 2021 Feb;209:111771
Clinical and molecular characterization of thirty Chinese patients with congenital lipoid adrenal hyperplasia.
Zhang T, Ma X, Wang J, Jia C, Wang W, Dong Z, Ye L, Sun S, Hu R, Ning G, Li C, Lu W
The Journal of steroid biochemistry and molecular biology 2021 Feb;206:105788
The Journal of steroid biochemistry and molecular biology 2021 Feb;206:105788
Viral RNA-binding ability conferred by SUMOylation at PB1 K612 of influenza A virus is essential for viral pathogenesis and transmission.
Li J, Liang L, Jiang L, Wang Q, Wen X, Zhao Y, Cui P, Zhang Y, Wang G, Li Q, Deng G, Shi J, Tian G, Zeng X, Jiang Y, Liu L, Chen H, Li C
PLoS pathogens 2021 Feb;17(2):e1009336
PLoS pathogens 2021 Feb;17(2):e1009336
Predicting therapeutic drugs for hepatocellular carcinoma based on tissue-specific pathways.
Yu L, Wang M, Yang Y, Xu F, Zhang X, Xie F, Gao L, Li X
PLoS computational biology 2021 Feb;17(2):e1008696
PLoS computational biology 2021 Feb;17(2):e1008696
Cryptotanshinone specifically suppresses NLRP3 inflammasome activation and protects against inflammasome-mediated diseases.
Liu H, Zhan X, Xu G, Wang Z, Li R, Wang Y, Qin Q, Shi W, Hou X, Yang R, Wang J, Xiao X, Bai Z
Pharmacological research 2021 Feb;164:105384
Pharmacological research 2021 Feb;164:105384
Genistein inhibits radiation-induced invasion and migration of glioblastoma cells by blocking the DNA-PKcs/Akt2/Rac1 signaling pathway.
Liu X, Wang Q, Liu B, Zheng X, Li P, Zhao T, Jin X, Ye F, Zhang P, Chen W, Li Q
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 2021 Feb;155:93-104
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 2021 Feb;155:93-104
20-HETE downregulates Na/K-ATPase α1 expression via the ubiquitination pathway.
Zhang B, Xu R, Fang G, Zhao Y
Prostaglandins & other lipid mediators 2021 Feb;152:106503
Prostaglandins & other lipid mediators 2021 Feb;152:106503
Loss of STAT5A promotes glucose metabolism and tumor growth through miRNA-23a-AKT signaling in hepatocellular carcinoma.
Jiang Y, Tao Y, Zhang X, Wei X, Li M, He X, Zhou B, Guo W, Yin H, Cheng S
Molecular oncology 2021 Feb;15(2):710-724
Molecular oncology 2021 Feb;15(2):710-724
Compound heterozygous mutation of the ASXL3 gene causes autosomal recessive congenital heart disease.
Fu F, Li R, Lei TY, Wang D, Yang X, Han J, Pan M, Zhen L, Li J, Li FT, Jing XY, Li DZ, Liao C
Human genetics 2021 Feb;140(2):333-348
Human genetics 2021 Feb;140(2):333-348
Whole-Transcriptome Profiling of Human Heart Tissues Reveals the Potential Novel Players and Regulatory Networks in Different Cardiomyopathy Subtypes of Heart Failure.
Liu CF, Ni Y, Moravec CS, Morley M, Ashley EA, Cappola TP, Margulies KB, Tang WHW
Circulation. Genomic and precision medicine 2021 Feb;14(1):e003142
Circulation. Genomic and precision medicine 2021 Feb;14(1):e003142
Knockdown of dual oxidase 1 suppresses activin A-induced fibrosis in cardiomyocytes via the reactive oxygen species-dependent pyroptotic pathway.
Li S, Li Z, Yin R, Nie J, Fu Y, Ying R
The international journal of biochemistry & cell biology 2021 Feb;131:105902
The international journal of biochemistry & cell biology 2021 Feb;131:105902
MicroRNA-520c-3p targeting of RelA/p65 suppresses atherosclerotic plaque formation.
Wang J, Hu X, Hu X, Gao F, Li M, Cui Y, Wei X, Qin Y, Zhang C, Zhao Y, Gao Y
The international journal of biochemistry & cell biology 2021 Feb;131:105873
The international journal of biochemistry & cell biology 2021 Feb;131:105873
MiR-146a mediates TLR-4 signaling pathway to affect myocardial fibrosis in rat constrictive pericarditis model.
Xiao Y, Qiao W, Wang X, Sun L, Ren W
Journal of thoracic disease 2021 Feb;13(2):935-945
Journal of thoracic disease 2021 Feb;13(2):935-945
RabGEF1 functions as an oncogene in U251 glioblastoma cells and is involved in regulating AKT and Erk pathways.
Fan H, Xin T, Dong X, Yang F, Zhang R, Feng S, He D, Guo H, Pang Q
Experimental and molecular pathology 2021 Feb;118:104571
Experimental and molecular pathology 2021 Feb;118:104571
A loss-of-function mutation p.T256M in NDRG4 is implicated in the pathogenesis of pulmonary atresia with ventricular septal defect (PA/VSD) and tetralogy of Fallot (TOF).
Peng J, Wang Q, Meng Z, Wang J, Zhou Y, Zhou S, Song W, Chen S, Chen AF, Sun K
FEBS open bio 2021 Feb;11(2):375-385
FEBS open bio 2021 Feb;11(2):375-385
Layer-by-layer self-assembly polyelectrolytes loaded with cyclic adenosine monophosphate enhances the osteo/odontogenic differentiation of stem cells from apical papilla.
Zhang J, Zhao IS, Yu OY, Li Q, Mei ML, Zhang C, Chu CH
Journal of biomedical materials research. Part A 2021 Feb;109(2):207-218
Journal of biomedical materials research. Part A 2021 Feb;109(2):207-218
HOXA10 mediates epithelial-mesenchymal transition to promote gastric cancer metastasis partly via modulation of TGFB2/Smad/METTL3 signaling axis.
Song C, Zhou C
Journal of experimental & clinical cancer research : CR 2021 Feb 9;40(1):62
Journal of experimental & clinical cancer research : CR 2021 Feb 9;40(1):62
FKBP10 promotes proliferation of glioma cells via activating AKT-CREB-PCNA axis.
Cai HQ, Zhang MJ, Cheng ZJ, Yu J, Yuan Q, Zhang J, Cai Y, Yang LY, Zhang Y, Hao JJ, Wang MR, Wan JH
Journal of biomedical science 2021 Feb 9;28(1):13
Journal of biomedical science 2021 Feb 9;28(1):13
DDB2 regulates DNA replication through PCNA-independent degradation of CDT2.
Wu X, Yu M, Zhang Z, Leng F, Ma Y, Xie N, Lu F
Cell & bioscience 2021 Feb 8;11(1):34
Cell & bioscience 2021 Feb 8;11(1):34
miR-374 improves cerebral ischemia reperfusion injury by targeting Wnt5a.
Xing F, Liu Y, Dong R, Cheng Y
Experimental animals 2021 Feb 6;70(1):126-136
Experimental animals 2021 Feb 6;70(1):126-136
Adipocyte-specific deletion of zinc finger protein 407 results in lipodystrophy and insulin resistance in mice.
Charrier A, Xu X, Guan BJ, Ngo J, Wynshaw-Boris A, Hatzoglou M, Buchner DA
Molecular and cellular endocrinology 2021 Feb 5;521:111109
Molecular and cellular endocrinology 2021 Feb 5;521:111109
Humanin regulates oxidative stress in the ovaries of polycystic ovary syndrome patients via the Keap1/Nrf2 pathway.
Wang Y, Li N, Zeng Z, Tang L, Zhao S, Zhou F, Zhou L, Xia W, Zhu C, Rao M
Molecular human reproduction 2021 Feb 5;27(2)
Molecular human reproduction 2021 Feb 5;27(2)
RTN1-C mediates cerebral ischemia/reperfusion injury via modulating autophagy.
Ling J, Cai H, Lin M, Qi S, Du J, Chen L
Acta biochimica et biophysica Sinica 2021 Feb 4;53(2):170-178
Acta biochimica et biophysica Sinica 2021 Feb 4;53(2):170-178
Long non-coding RNA CCDC183-AS1 acts AS a miR-589-5p sponge to promote the progression of hepatocellular carcinoma through regulating SKP1 expression.
Zhu H, Zhang H, Pei Y, Liao Z, Liu F, Su C, Liu Y, Dong R, Song J, Zhang X, Fan Y, Liang H, Zhang B, Chen X
Journal of experimental & clinical cancer research : CR 2021 Feb 4;40(1):57
Journal of experimental & clinical cancer research : CR 2021 Feb 4;40(1):57
miR-224-5p Contained in Urinary Extracellular Vesicles Regulates PD-L1 Expression by Inhibiting Cyclin D1 in Renal Cell Carcinoma Cells.
Qin Z, Hu H, Sun W, Chen L, Jin S, Xu Q, Liu Y, Yu L, Zeng S
Cancers 2021 Feb 4;13(4)
Cancers 2021 Feb 4;13(4)
Angiopoietin 2 stimulates trophoblast invasion via a mechanism associated with JNK signaling.
Hou H, Ning F, Zhang JY, Lu Q, Zhang M, Wu P, Chen M, Lash GE
Molecular human reproduction 2021 Feb 27;27(3)
Molecular human reproduction 2021 Feb 27;27(3)
Prpf31 is essential for the survival and differentiation of retinal progenitor cells by modulating alternative splicing.
Li J, Liu F, Lv Y, Sun K, Zhao Y, Reilly J, Zhang Y, Tu J, Yu S, Liu X, Qin Y, Huang Y, Gao P, Jia D, Chen X, Han Y, Shu X, Luo D, Tang Z, Liu M
Nucleic acids research 2021 Feb 26;49(4):2027-2043
Nucleic acids research 2021 Feb 26;49(4):2027-2043
Cancer-associated fibroblast-derived SDF-1 induces epithelial-mesenchymal transition of lung adenocarcinoma via CXCR4/β-catenin/PPARδ signalling.
Wang Y, Lan W, Xu M, Song J, Mao J, Li C, Du X, Jiang Y, Li E, Zhang R, Wang Q
Cell death & disease 2021 Feb 26;12(2):214
Cell death & disease 2021 Feb 26;12(2):214
UBE3C promotes proliferation and inhibits apoptosis by activating the β-catenin signaling via degradation of AXIN1 in gastric cancer.
Zhang Y, Xu J, Fu H, Wei Z, Yang D, Yan R
Carcinogenesis 2021 Feb 25;42(2):285-293
Carcinogenesis 2021 Feb 25;42(2):285-293
Inhibition of the Otub1/c-Maf axis by the herbal acevaltrate induces myeloma cell apoptosis.
Sun T, Xu Y, Xu Z, Cao B, Zhang Z, Wang Q, Kong Y, Mao X
Cell communication and signaling : CCS 2021 Feb 24;19(1):24
Cell communication and signaling : CCS 2021 Feb 24;19(1):24
Radiotherapy and immunotherapy converge on elimination of tumor-promoting erythroid progenitor cells through adaptive immunity.
Hou Y, Liang HL, Yu X, Liu Z, Cao X, Rao E, Huang X, Wang L, Li L, Bugno J, Fu Y, Chmura SJ, Wu W, Luo SZ, Zheng W, Arina A, Jutzy J, McCall AR, Vokes EE, Pitroda SP, Fu YX, Weichselbaum RR
Science translational medicine 2021 Feb 24;13(582)
Science translational medicine 2021 Feb 24;13(582)
p53 induces ARTS to promote mitochondrial apoptosis.
Hao Q, Chen J, Liao J, Huang Y, Gan Y, Larisch S, Zeng SX, Lu H, Zhou X
Cell death & disease 2021 Feb 24;12(2):204
Cell death & disease 2021 Feb 24;12(2):204
Pterostilbene inhibits gallbladder cancer progression by suppressing the PI3K/Akt pathway.
Tong C, Wang Y, Li J, Cen W, Zhang W, Zhu Z, Yu J, Lu B
Scientific reports 2021 Feb 23;11(1):4391
Scientific reports 2021 Feb 23;11(1):4391
Genome-wide analysis of pseudogenes reveals HBBP1's human-specific essentiality in erythropoiesis and implication in β-thalassemia.
Ma Y, Liu S, Gao J, Chen C, Zhang X, Yuan H, Chen Z, Yin X, Sun C, Mao Y, Zhou F, Shao Y, Liu Q, Xu J, Cheng L, Yu D, Li P, Yi P, He J, Geng G, Guo Q, Si Y, Zhao H, Li H, Banes GL, Liu H, Nakamura Y, Kurita R, Huang Y, Wang X, Wang F, Fang G, Engel JD, Shi L, Zhang YE, Yu J
Developmental cell 2021 Feb 22;56(4):478-493.e11
Developmental cell 2021 Feb 22;56(4):478-493.e11
Abnormal level of paxillin in cervical cancer cells is involved in tumor progression and invasion.
Gu H, Wen J
Acta biochimica Polonica 2021 Feb 20;68(1):49-53
Acta biochimica Polonica 2021 Feb 20;68(1):49-53
Nuclear factor Y participates in alcoholic liver disease by activating SREBP1 expression in mice.
Zhang Y, Sun Y, Zhang Y, Miao Q, Wang Q, Yang B, Li Y, Li L, Zhang R
Biochemical and biophysical research communications 2021 Feb 19;541:90-94
Biochemical and biophysical research communications 2021 Feb 19;541:90-94
SFPQ regulates the accumulation of RNA foci and dipeptide repeat proteins from the expanded repeat mutation in C9orf72.
Malnar M, Rogelj B
Journal of cell science 2021 Feb 19;134(4)
Journal of cell science 2021 Feb 19;134(4)
GBP5 drives malignancy of glioblastoma via the Src/ERK1/2/MMP3 pathway.
Yu X, Jin J, Zheng Y, Zhu H, Xu H, Ma J, Lan Q, Zhuang Z, Chen CC, Li M
Cell death & disease 2021 Feb 19;12(2):203
Cell death & disease 2021 Feb 19;12(2):203
LncRNA CDKN2B-AS1 stabilized by IGF2BP3 drives the malignancy of renal clear cell carcinoma through epigenetically activating NUF2 transcription.
Xie X, Lin J, Fan X, Zhong Y, Chen Y, Liu K, Ren Y, Chen X, Lai D, Li X, Li Z, Tang A
Cell death & disease 2021 Feb 19;12(2):201
Cell death & disease 2021 Feb 19;12(2):201
E3 ligase Nedd4l promotes antiviral innate immunity by catalyzing K29-linked cysteine ubiquitination of TRAF3.
Gao P, Ma X, Yuan M, Yi Y, Liu G, Wen M, Jiang W, Ji R, Zhu L, Tang Z, Yu Q, Xu J, Yang R, Xia S, Yang M, Pan J, Yuan H, An H
Nature communications 2021 Feb 19;12(1):1194
Nature communications 2021 Feb 19;12(1):1194
LncRNA HOXA-AS3 promotes gastric cancer progression by regulating miR-29a-3p/LTβR and activating NF-κB signaling.
Qu F, Zhu B, Hu YL, Mao QS, Feng Y
Cancer cell international 2021 Feb 18;21(1):118
Cancer cell international 2021 Feb 18;21(1):118
Critical roles of sphingosine kinase 1 in the regulation of neuroinflammation and neuronal injury after spinal cord injury.
Wang C, Xu T, Lachance BB, Zhong X, Shen G, Xu T, Tang C, Jia X
Journal of neuroinflammation 2021 Feb 18;18(1):50
Journal of neuroinflammation 2021 Feb 18;18(1):50
Direct activation of endothelial cells by SARS-CoV-2 nucleocapsid protein is blocked by Simvastatin.
Qian Y, Lei T, Patel PS, Lee CH, Monaghan-Nichols P, Xin HB, Qiu J, Fu M
bioRxiv : the preprint server for biology 2021 Feb 18;
bioRxiv : the preprint server for biology 2021 Feb 18;
Hepatic connective tissue growth factor expression and regulation differ between non-steatotic and non-alcoholic steatotic livers from brain-dead donor.
Yang DJ, Shi JH, Xia ZP, Guo WZ, Ahmed MS, Zhang SJ
Scientific reports 2021 Feb 16;11(1):3857
Scientific reports 2021 Feb 16;11(1):3857
CREB1 protects against the renal injury in a rat model of kidney stone disease and calcium oxalate monohydrate crystals-induced injury in NRK-52E cells.
Yu L, Gan X, Bai Y, An R
Toxicology and applied pharmacology 2021 Feb 15;413:115394
Toxicology and applied pharmacology 2021 Feb 15;413:115394
Down-regulation of A(3)AR signaling by IL-6-induced GRK2 activation contributes to Th17 cell differentiation.
Hu S, Guo P, Wang Z, Zhou Z, Wang R, Zhang M, Tao J, Tai Y, Zhou W, Wei W, Wang Q
Experimental cell research 2021 Feb 15;399(2):112482
Experimental cell research 2021 Feb 15;399(2):112482
Nobiletin downregulates the SKP2-p21/p27-CDK2 axis to inhibit tumor progression and shows synergistic effects with palbociclib on renal cell carcinoma.
Chen T, Liu L, Zou Y, Hu X, Zhang W, Zhou T, Luo X, Fu W, Xu J
Cancer biology & medicine 2021 Feb 15;18(1):227-244
Cancer biology & medicine 2021 Feb 15;18(1):227-244
RECQL4 regulates DNA damage response and redox homeostasis in esophageal cancer.
Lyu G, Su P, Hao X, Chen S, Ren S, Zhao Z, Gong Y, Liu Q, Shao C
Cancer biology & medicine 2021 Feb 15;18(1):120-138
Cancer biology & medicine 2021 Feb 15;18(1):120-138
Gentisic acid prevents diet-induced obesity in mice by accelerating the thermogenesis of brown adipose tissue.
Han X, Guo J, Gao Y, Zhan J, You Y, Huang W
Food & function 2021 Feb 15;12(3):1262-1270
Food & function 2021 Feb 15;12(3):1262-1270
Uric acid inhibits HMGB1-TLR4-NF-κB signaling to alleviate oxygen-glucose deprivation/reoxygenation injury of microglia.
Wang Q, Zhao H, Gao Y, Lu J, Xie D, Yu W, He F, Liu W, Hisatome I, Yamamoto T, Wang W, Cheng J
Biochemical and biophysical research communications 2021 Feb 12;540:22-28
Biochemical and biophysical research communications 2021 Feb 12;540:22-28
A novel regulatory loop miR-101/ANXA2/EGR1 mediates malignant characteristics of liver cancer stem cells.
Ma S, Cheng J, Wang H, Ding N, Zhou F, Ji R, Zhu L, Zhu C, Pan Y
Carcinogenesis 2021 Feb 11;42(1):93-104
Carcinogenesis 2021 Feb 11;42(1):93-104
DUOX2 promotes the progression of colorectal cancer cells by regulating the AKT pathway and interacting with RPL3.
Zhang X, Han J, Feng L, Zhi L, Jiang D, Yu B, Zhang Z, Gao B, Zhang C, Li M, Zhao L, Wang G
Carcinogenesis 2021 Feb 11;42(1):105-117
Carcinogenesis 2021 Feb 11;42(1):105-117
Icariside I specifically facilitates ATP or nigericin-induced NLRP3 inflammasome activation and causes idiosyncratic hepatotoxicity.
Gao Y, Xu G, Ma L, Shi W, Wang Z, Zhan X, Qin N, He T, Guo Y, Niu M, Wang J, Bai Z, Xiao X
Cell communication and signaling : CCS 2021 Feb 11;19(1):13
Cell communication and signaling : CCS 2021 Feb 11;19(1):13
The DNA methylation-regulated MCTP1 activates the drug-resistance of esophageal cancer cells.
Kong L, Yang W, Chen L, Qian L
Aging 2021 Feb 11;13(3):3342-3352
Aging 2021 Feb 11;13(3):3342-3352
Formononetin attenuates atopic dermatitis by upregulating A20 expression via activation of G protein-coupled estrogen receptor.
Yuan W, Chen Y, Zhou Y, Bao K, Yu X, Xu Y, Zhang Y, Zheng J, Jiang G, Hong M
Journal of ethnopharmacology 2021 Feb 10;266:113397
Journal of ethnopharmacology 2021 Feb 10;266:113397
Gas6 or Mer deficiency ameliorates silica-induced autophagosomes accumulation in mice lung.
Li W, Xie L, Ma J, Cheng M, Fan L, Xu Y, Wang B, Chen W
Toxicology letters 2021 Feb 1;337:28-37
Toxicology letters 2021 Feb 1;337:28-37
Berberine regulates macrophage polarization through IL-4-STAT6 signaling pathway in Helicobacter pylori-induced chronic atrophic gastritis.
Yang T, Wang R, Liu H, Wang L, Li J, Wu S, Chen X, Yang X, Zhao Y
Life sciences 2021 Feb 1;266:118903
Life sciences 2021 Feb 1;266:118903
The PDZ Domain Protein SYNJ2BP Regulates GRK-Dependent Sst2A Phosphorylation and Downstream MAPK Signaling.
Carr HS, Chang JT, Frost JA
Endocrinology 2021 Feb 1;162(2)
Endocrinology 2021 Feb 1;162(2)
ATM inhibition enhances cancer immunotherapy by promoting mtDNA leakage and cGAS/STING activation.
Hu M, Zhou M, Bao X, Pan D, Jiao M, Liu X, Li F, Li CY
The Journal of clinical investigation 2021 Feb 1;131(3)
The Journal of clinical investigation 2021 Feb 1;131(3)
The S1PR1 agonist SEW2871 promotes the survival of skin flap.
Zhang D, Qi D, Xu Y, Hu C, Zhang X, Yang Q, Shang Z, Zhang G
Canadian journal of physiology and pharmacology 2021 Dec;99(12):1280-1287
Canadian journal of physiology and pharmacology 2021 Dec;99(12):1280-1287
Red ginseng has stronger anti-aging effects compared to ginseng possibly due to its regulation of oxidative stress and the gut microbiota.
Peng X, Hao M, Zhao Y, Cai Y, Chen X, Chen H, Zhang Y, Dong L, Liu X, Ding C, Liu W, Yang M, Luo Y
Phytomedicine : international journal of phytotherapy and phytopharmacology 2021 Dec;93:153772
Phytomedicine : international journal of phytotherapy and phytopharmacology 2021 Dec;93:153772
LncRNA CAIF suppresses LPS-induced inflammation and apoptosis of cardiomyocytes through regulating miR-16 demethylation.
Wang Y, Zhang Y
Immunity, inflammation and disease 2021 Dec;9(4):1468-1478
Immunity, inflammation and disease 2021 Dec;9(4):1468-1478
Long non-coding RNA AC122108.1 promotes lung adenocarcinoma brain metastasis and progression through the Wnt/β-catenin pathway by directly binding to aldolase A.
Feng S, Liu H, Du P, Dong X, Pang Q, Guo H
Annals of translational medicine 2021 Dec;9(23):1729
Annals of translational medicine 2021 Dec;9(23):1729
Mechanism of neutrophil extracellular traps generation and their role in trophoblasts apoptosis in gestational diabetes mellitus.
Shen D, Lu Y, Li G, Hu M, Li S, Ju H, Zhang M, Wang X
Cellular signalling 2021 Dec;88:110168
Cellular signalling 2021 Dec;88:110168
Ginsenoside Rb1 alleviates liver injury induced by 3-chloro-1,2-propanediol by stimulating autophagic flux.
Lu J, Lu J, Bu X, Li Y, Ge G, Guan S
Journal of food science 2021 Dec;86(12):5503-5515
Journal of food science 2021 Dec;86(12):5503-5515
Maternal Benzophenone Exposure Impairs Hippocampus Development and Cognitive Function in Mouse Offspring.
Cui F, Pan Q, Wang S, Zhao F, Wang R, Zhang T, Song Y, He J, Zhang H, Weng Q, Jin Y, Xia W, Li Y, Yang GY, De Vos WH, Timmermans JP, Xu S, Tang Y, Sheng X
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2021 Dec;8(23):e2102686
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2021 Dec;8(23):e2102686
Targeting conserved N-glycosylation blocks SARS-CoV-2 variant infection in vitro.
Huang HC, Lai YJ, Liao CC, Yang WF, Huang KB, Lee IJ, Chou WC, Wang SH, Wang LH, Hsu JM, Sun CP, Kuo CT, Wang J, Hsiao TC, Yang PJ, Lee TA, Huang W, Li FA, Shen CY, Lin YL, Tao MH, Li CW
EBioMedicine 2021 Dec;74:103712
EBioMedicine 2021 Dec;74:103712
MiR-192-5p suppresses M1 macrophage polarization via epiregulin (EREG) downregulation in gouty arthritis.
An L, Yin F
Tissue & cell 2021 Dec;73:101669
Tissue & cell 2021 Dec;73:101669
Molecular Mechanism of the ATF6α/S1P/S2P Signaling Pathway in Hippocampal Neuronal Apoptosis in SPS Rats.
Han L, Xu Y, Shi Y
Journal of molecular neuroscience : MN 2021 Dec;71(12):2487-2499
Journal of molecular neuroscience : MN 2021 Dec;71(12):2487-2499
Trametinib enhances ATRA-induced differentiation in AML cells.
Lu H, Li ZY, Ding M, Liang C, Weng XQ, Sheng Y, Wu J, Cai X
Leukemia & lymphoma 2021 Dec;62(14):3361-3372
Leukemia & lymphoma 2021 Dec;62(14):3361-3372
Increased expression of PSME2 is associated with clear cell renal cell carcinoma invasion by regulating BNIP3‑mediated autophagy.
Wang X, Wu F, Deng Y, Chai J, Zhang Y, He G, Li X
International journal of oncology 2021 Dec;59(6)
International journal of oncology 2021 Dec;59(6)
Wei Chang An pill regulates gastrointestinal motility in a bidirectional manner.
Jia S, Chai L, Zhang J, Zhang M, Li L, Qi Y, Pang Y, Chen X, Fan N, Wang L, Wang Y, Song J, Sun Y, Wang Y, Miao L, Zhang H
Pharmaceutical biology 2021 Dec;59(1):1452-1463
Pharmaceutical biology 2021 Dec;59(1):1452-1463
Nucleoporin 37 promotes the cell proliferation, migration, and invasion of gastric cancer through activating the PI3K/AKT/mTOR signaling pathway.
Zhang J, Lv W, Liu Y, Fu W, Chen B, Ma Q, Gao X, Cui X
In vitro cellular & developmental biology. Animal 2021 Dec;57(10):987-997
In vitro cellular & developmental biology. Animal 2021 Dec;57(10):987-997
Hypoxia-inducible factor-1α promotes proliferation of airway smooth muscle cells through miRNA-103-mediated signaling pathway under hypoxia.
Zhang C, Gao J, Zhu S
In vitro cellular & developmental biology. Animal 2021 Dec;57(10):944-952
In vitro cellular & developmental biology. Animal 2021 Dec;57(10):944-952
CoCrMo-Nanoparticles induced peri-implant osteolysis by promoting osteoblast ferroptosis via regulating Nrf2-ARE signalling pathway.
Xu Y, Sang W, Zhong Y, Xue S, Yang M, Wang C, Lu H, Huan R, Mao X, Zhu L, He C, Ma J
Cell proliferation 2021 Dec;54(12):e13142
Cell proliferation 2021 Dec;54(12):e13142
Bone marrow macrophage-derived exosomal miR-143-5p contributes to insulin resistance in hepatocytes by repressing MKP5.
Li L, Zuo H, Huang X, Shen T, Tang W, Zhang X, An T, Dou L, Li J
Cell proliferation 2021 Dec;54(12):e13140
Cell proliferation 2021 Dec;54(12):e13140
Splicing factor proline and glutamine rich intron retention, reduced expression and aggregate formation are pathological features of amyotrophic lateral sclerosis.
Hogan AL, Grima N, Fifita JA, McCann EP, Heng B, Fat SCM, Wu S, Maharjan R, Cain AK, Henden L, Rayner S, Tarr I, Zhang KY, Zhao Q, Zhang ZH, Wright A, Lee A, Morsch M, Yang S, Williams KL, Blair IP
Neuropathology and applied neurobiology 2021 Dec;47(7):990-1003
Neuropathology and applied neurobiology 2021 Dec;47(7):990-1003
Role of miR-145-5p/ CD40 in the inflammation and apoptosis of HUVECs induced by PM(2.5).
Zhang X, Qi W, Shi Y, Li X, Yin J, Huo C, Zhang R, Zhao W, Ye J, Zhou L, Ye L
Toxicology 2021 Dec;464:152993
Toxicology 2021 Dec;464:152993
Endoplasmic reticulum stress pathway mediates T-2 toxin-induced chondrocyte apoptosis.
Liu YN, Mu YD, Wang H, Zhang M, Shi YW, Mi G, Peng LX, Chen JH
Toxicology 2021 Dec;464:152989
Toxicology 2021 Dec;464:152989
YTHDF1 promotes the proliferation, migration, and invasion of prostate cancer cells by regulating TRIM44.
Li W, Chen G, Feng Z, Zhu B, Zhou L, Zhang Y, Mai J, Jiang C, Zeng J
Genes & genomics 2021 Dec;43(12):1413-1421
Genes & genomics 2021 Dec;43(12):1413-1421
Activation of SK3 channel plays a pivotal role in modulation of trigeminal neuralgia.
Zhao J, Zhang Y, Liu X, Rao Y, Fu J, Hua L, Ou C
Neurological research 2021 Dec;43(12):1005-1012
Neurological research 2021 Dec;43(12):1005-1012
Endothelial METTL3 (Methyltransferase-Like 3) Inhibits Fibrinolysis by Promoting PAI-1 (Plasminogen Activator Inhibitor-1) Expression Through Enhancing Jun Proto-Oncogene N6-Methyladenosine Modification.
Bai Q, Lu Y, Chen Y, Zhang H, Zhang W, Wu H, Wen A
Arteriosclerosis, thrombosis, and vascular biology 2021 Dec;41(12):2877-2889
Arteriosclerosis, thrombosis, and vascular biology 2021 Dec;41(12):2877-2889
Exposure interval to ambient fine particulate matter (PM2.5) collected in Southwest China induced pulmonary damage through the Janus tyrosine protein kinase-2/signal transducer and activator of transcription-3 signaling pathway both in vivo and in vitro.
Yue W, Chen X, He S, Li N, Zhang L, Chen J
Journal of applied toxicology : JAT 2021 Dec;41(12):2042-2054
Journal of applied toxicology : JAT 2021 Dec;41(12):2042-2054
Lobetyolin inhibits the proliferation of breast cancer cells via ASCT2 down-regulation-induced apoptosis.
Chen Y, Tian Y, Jin G, Cui Z, Guo W, Zhang X, Liu X
Human & experimental toxicology 2021 Dec;40(12):2074-2086
Human & experimental toxicology 2021 Dec;40(12):2074-2086
AK003290 Protects Myocardial Cells Against Apoptosis and Promotes Cardiac Function Recovery Via miR-539-3p/ErbB4 Axis in Ischemic-Reperfusion Injury.
Tang Y, Tang Y, Xiang Y, Yan J, Guo K
DNA and cell biology 2021 Dec;40(12):1528-1538
DNA and cell biology 2021 Dec;40(12):1528-1538
Insulin-like growth factor reduced against decabromodiphenyl ether-209-induced neurodevelopmental toxicity in vivo and in vitro.
Yang Y, He Q, Zhang Z, Qi C, Ding L, Yuan T, Chen Y, Li Z
Human & experimental toxicology 2021 Dec;40(12_suppl):S475-S486
Human & experimental toxicology 2021 Dec;40(12_suppl):S475-S486
Non-canonical activation of the ER stress sensor ATF6 by Legionella pneumophila effectors.
Ibe NU, Subramanian A, Mukherjee S
Life science alliance 2021 Dec;4(12)
Life science alliance 2021 Dec;4(12)
Expression of CD47 in the pancreatic β-cells of people with recent-onset type 1 diabetes varies according to disease endotype.
Leslie KA, Richardson SJ, Russell MA, Morgan NG
Diabetic medicine : a journal of the British Diabetic Association 2021 Dec;38(12):e14724
Diabetic medicine : a journal of the British Diabetic Association 2021 Dec;38(12):e14724
Caspase-8 Regulates the Antimyeloma Activity of Bortezomib and Lenalidomide.
Zhou L, Huang X, Niesvizky R, Pu Z, Xu G
The Journal of pharmacology and experimental therapeutics 2021 Dec;379(3):303-309
The Journal of pharmacology and experimental therapeutics 2021 Dec;379(3):303-309
Two Inhibitors Against the 3C-Like Proteases of Swine Coronavirus and Feline Coronavirus.
Zhou M, Han Y, Li M, Ye G, Peng G
Virologica Sinica 2021 Dec;36(6):1421-1430
Virologica Sinica 2021 Dec;36(6):1421-1430
Angiomotin-like 1 plays a tumor-promoting role in glioma by enhancing the activation of YAP1 signaling.
Xu G, Seng Z, Zhang M, Qu J
Environmental toxicology 2021 Dec;36(12):2500-2511
Environmental toxicology 2021 Dec;36(12):2500-2511
Amelioratory effect of neoandrographolide on myocardial ischemic-reperfusion injury by its anti-inflammatory and anti-apoptotic activities.
Liu Y, Liu Y, Zhang HL, Yu FF, Yin XR, Zhao YF, Ye F, Wu XQ
Environmental toxicology 2021 Dec;36(12):2367-2379
Environmental toxicology 2021 Dec;36(12):2367-2379
Dual inhibition of EGFR and IL-6-STAT3 signalling by miR-146b: a potential targeted therapy for epithelial ovarian cancer.
Yan M, Han M, Yang X, Shen R, Wang H, Zhang L, Xia S, Yang P, Zhai G, Shao Q
Journal of enzyme inhibition and medicinal chemistry 2021 Dec;36(1):1905-1915
Journal of enzyme inhibition and medicinal chemistry 2021 Dec;36(1):1905-1915
CircPrkcsh, a circular RNA, contributes to the polarization of microglia towards the M1 phenotype induced by spinal cord injury and acts via the JNK/p38 MAPK pathway.
Li X, Kang J, Lv H, Liu R, Chen J, Zhang Y, Zhang Y, Yu G, Zhang X, Ning B
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 Dec;35(12):e22014
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 Dec;35(12):e22014
BAIAP2L2 promotes the proliferation, migration and invasion of osteosarcoma associated with the Wnt/β-catenin pathway.
Guo H, Peng J, Hu J, Chang S, Liu H, Luo H, Chen X, Tang H, Chen Y
Journal of bone oncology 2021 Dec;31:100393
Journal of bone oncology 2021 Dec;31:100393
Mdivi-1 alleviates atopic dermatitis through the inhibition of NLRP3 inflammasome.
Li L, Mu Z, Liu P, Wang Y, Yang F, Han X
Experimental dermatology 2021 Dec;30(12):1734-1744
Experimental dermatology 2021 Dec;30(12):1734-1744
Mitophagy mediates metabolic reprogramming of induced pluripotent stem cells undergoing endothelial differentiation.
Krantz S, Kim YM, Srivastava S, Leasure JW, Toth PT, Marsboom G, Rehman J
The Journal of biological chemistry 2021 Dec;297(6):101410
The Journal of biological chemistry 2021 Dec;297(6):101410
Blockade of JAK2 signaling produces immunomodulatory effect to preserve pancreatic homeostasis in severe acute pancreatitis.
Qiu Z, Xu F, Wang Z, Yang P, Bu Z, Cheng F, Jiang H, Li L, Zhang F
Biochemistry and biophysics reports 2021 Dec;28:101133
Biochemistry and biophysics reports 2021 Dec;28:101133
Protective effect of Idelalisib on carbon tetrachloride-induced liver fibrosis via microRNA-124-3P/phosphatidylinositol-3-hydroxykinase signalling pathway.
Li X, Li H, Zhang S, Zhang R, Li J, Wei Y, Yang C, Zhang F, Zhou H
Journal of cellular and molecular medicine 2021 Dec;25(24):11185-11197
Journal of cellular and molecular medicine 2021 Dec;25(24):11185-11197
MET inhibition enhances PARP inhibitor efficacy in castration-resistant prostate cancer by suppressing the ATM/ATR and PI3K/AKT pathways.
Zhou S, Dai Z, Wang L, Gao X, Yang L, Wang Z, Wang Q, Liu Z
Journal of cellular and molecular medicine 2021 Dec;25(24):11157-11169
Journal of cellular and molecular medicine 2021 Dec;25(24):11157-11169
Huoxin pill prevents acute myocardial ischaemia injury via inhibition of Wnt/β-catenin signaling.
Wang Q, Ma E, Wo D, Chen J, He J, Peng J, Zhu W, Ren DN
Journal of cellular and molecular medicine 2021 Dec;25(24):11053-11062
Journal of cellular and molecular medicine 2021 Dec;25(24):11053-11062
Depletion of m(6) A reader protein YTHDC1 induces dilated cardiomyopathy by abnormal splicing of Titin.
Gao S, Sun H, Chen K, Gu X, Chen H, Jiang L, Chen L, Zhang S, Liu Y, Shi D, Liang D, Xu L, Yang J, Ruan Y, Chen H, Shen B, Ma H, Chen YH
Journal of cellular and molecular medicine 2021 Dec;25(23):10879-10891
Journal of cellular and molecular medicine 2021 Dec;25(23):10879-10891
hsa‑miR‑429 targets CBX8 to promote cell apoptosis in diffuse large B‑cell lymphoma.
Liang Y, Yu ZJ, Liu M, Liu HM, Zhang JZ, Xiong T, Tang YY, Huang ZP
Molecular medicine reports 2021 Dec;24(6)
Molecular medicine reports 2021 Dec;24(6)
Peroxisome proliferator‑activated receptor β/δ regulates cerebral vasospasm after subarachnoid hemorrhage via modulating vascular smooth muscle cells phenotypic conversion.
Xu L, Wu J, Liu Y, Chen G, Ma C, Zhang H
Molecular medicine reports 2021 Dec;24(6)
Molecular medicine reports 2021 Dec;24(6)
Huoxue Qianyang Qutan recipe attenuates Ang II-induced cardiomyocyte hypertrophy by regulating reactive oxygen species production.
Gui M, Yao L, Lu B, Wang J, Zhou X, Li J, Dong Z, Fu D
Experimental and therapeutic medicine 2021 Dec;22(6):1446
Experimental and therapeutic medicine 2021 Dec;22(6):1446
MicroRNA-602 prevents the development of inflammatory bowel diseases in a microbiota-dependent manner.
Zhao S, Zhu L, Feng W, Zhang L, Chen DD, Hu YC, Shen H
Experimental and therapeutic medicine 2021 Dec;22(6):1373
Experimental and therapeutic medicine 2021 Dec;22(6):1373
Hsa-miR-335 enhances cell migration and invasion in lung adenocarcinoma through targeting Copine-1.
Wang Y, Zhang J, Zhong LY, Huang SJ, Yu NN, Ouyang L, Niu YL, Chen JX, Lu CH, He QY
MedComm 2021 Dec;2(4):810-820
MedComm 2021 Dec;2(4):810-820
Diterpenoid alkaloids from Delphinium forrestii var. viride and their anti-inflammation activity.
Song Z, Gao C, Jiang Q, Xu J, Xiong L, Liu K, Sun D, Li H, Chen L
Phytochemistry 2021 Dec;192:112971
Phytochemistry 2021 Dec;192:112971
MicroRNA-455-5p/CPEB1 pathway mediates Aβ-related learning and memory deficits in a mouse model of Alzheimer's disease.
Xiao G, Chen Q, Zhang X
Brain research bulletin 2021 Dec;177:282-294
Brain research bulletin 2021 Dec;177:282-294
Resveratrol and its derivative pterostilbene attenuate oxidative stress-induced intestinal injury by improving mitochondrial redox homeostasis and function via SIRT1 signaling.
Chen Y, Zhang H, Ji S, Jia P, Chen Y, Li Y, Wang T
Free radical biology & medicine 2021 Dec;177:1-14
Free radical biology & medicine 2021 Dec;177:1-14
Isosteroidal alkaloids from Fritillaria hupehensis Hsiao et K.C.Hsia: Synthesis and biological evaluation of alkaloid derivatives as potential cytotoxic agents.
Liu XH, Zou J, Li YJ, Liu M, He CL, Liu YR, Wang JZ, Chen DL
Steroids 2021 Dec;176:108929
Steroids 2021 Dec;176:108929
c-Jun N-terminal kinase (JNK) signaling contributes to cystic burden in polycystic kidney disease.
Smith AO, Jonassen JA, Preval KM, Davis RJ, Pazour GJ
PLoS genetics 2021 Dec;17(12):e1009711
PLoS genetics 2021 Dec;17(12):e1009711
CUL3 (cullin 3)-mediated ubiquitination and degradation of BECN1 (beclin 1) inhibit autophagy and promote tumor progression.
Li X, Yang KB, Chen W, Mai J, Wu XQ, Sun T, Wu RY, Jiao L, Li DD, Ji J, Zhang HL, Yu Y, Chen YH, Feng GK, Deng R, Li JD, Zhu XF
Autophagy 2021 Dec;17(12):4323-4340
Autophagy 2021 Dec;17(12):4323-4340
Ferritinophagy is involved in the zinc oxide nanoparticles-induced ferroptosis of vascular endothelial cells.
Qin X, Zhang J, Wang B, Xu G, Yang X, Zou Z, Yu C
Autophagy 2021 Dec;17(12):4266-4285
Autophagy 2021 Dec;17(12):4266-4285
Long noncoding RNA (lncRNA) EIF3J-DT induces chemoresistance of gastric cancer via autophagy activation.
Luo Y, Zheng S, Wu Q, Wu J, Zhou R, Wang C, Wu Z, Rong X, Huang N, Sun L, Bin J, Liao Y, Shi M, Liao W
Autophagy 2021 Dec;17(12):4083-4101
Autophagy 2021 Dec;17(12):4083-4101
Lanthanum chloride induces autophagy in primary cultured rat cortical neurons through Akt/mTOR and AMPK/mTOR signaling pathways.
Gao X, Yu M, Sun W, Han Y, Yang J, Lu X, Jin C, Wu S, Cai Y
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2021 Dec;158:112632
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2021 Dec;158:112632
Pentagalloylglucose reduces AGE-induced inflammation by activating Nrf2/HO-1 and inhibiting the JAK2/STAT3 pathway in mesangial cells.
Tong J, Fang J, Zhu T, Xiang P, Shang J, Chen L, Zhao J, Wang Y, Tong L, Sun M
Journal of pharmacological sciences 2021 Dec;147(4):305-314
Journal of pharmacological sciences 2021 Dec;147(4):305-314
Pyruvate kinase M2 (PKM2) interacts with activating transcription factor 2 (ATF2) to bridge glycolysis and pyroptosis in microglia.
Li M, Lu H, Wang X, Duan C, Zhu X, Zhang Y, Ge X, Ji F, Wang X, Su J, Zhang D
Molecular immunology 2021 Dec;140:250-266
Molecular immunology 2021 Dec;140:250-266
LncRNA RP1-86C11.7 exacerbates the glioma progression and oncogenicity by hsa-miR-144-3p/TFRC signaling.
Ma Q, Wang X, Li J
Translational oncology 2021 Dec;14(12):101215
Translational oncology 2021 Dec;14(12):101215
Ablation of USP21 in skeletal muscle promotes oxidative fibre phenotype, inhibiting obesity and type 2 diabetes.
Kim A, Koo JH, Jin X, Kim W, Park SY, Park S, Rhee EP, Choi CS, Kim SG
Journal of cachexia, sarcopenia and muscle 2021 Dec;12(6):1669-1689
Journal of cachexia, sarcopenia and muscle 2021 Dec;12(6):1669-1689
Linc00467 promotion of gastric cancer development by directly regulating miR-7-5p expression and downstream epidermal growth factor receptor.
Deng LH, Zhao H, Bai LP, Xie J, Liu K, Yan F
Bioengineered 2021 Dec;12(2):9484-9495
Bioengineered 2021 Dec;12(2):9484-9495
Hsa_circ_0030586 promotes epithelial-mesenchymal transition in prostate cancer via PI3K-AKT signaling.
Luo GC, Chen L, Fang J, Yan ZJ
Bioengineered 2021 Dec;12(2):11089-11107
Bioengineered 2021 Dec;12(2):11089-11107
MicroRNA-98-5p modulates cervical cancer progression via controlling PI3K/AKT pathway.
Xiao R, Wang H, Yang B
Bioengineered 2021 Dec;12(2):10596-10607
Bioengineered 2021 Dec;12(2):10596-10607
Ubiquitin-associated protein 2 like (UBAP2L) enhances growth and metastasis of gastric cancer cells.
Lin S, Yan Z, Tang Q, Zhang S
Bioengineered 2021 Dec;12(2):10232-10245
Bioengineered 2021 Dec;12(2):10232-10245
Orosomucoid 1 promotes epirubicin resistance in breast cancer by upregulating the expression of matrix metalloproteinases 2 and 9.
Qiong L, Yin J
Bioengineered 2021 Dec;12(1):8822-8832
Bioengineered 2021 Dec;12(1):8822-8832
Solid lipid nanoparticle delivery of rhynchophylline enhanced the efficiency of allergic asthma treatment via the upregulation of suppressor of cytokine signaling 1 by repressing the p38 signaling pathway.
Lv C, Li H, Cui H, Bi Q, Wang M
Bioengineered 2021 Dec;12(1):8635-8649
Bioengineered 2021 Dec;12(1):8635-8649
MiR-1224-5p attenuates polycystic ovary syndrome through inhibiting NOD-like receptor protein 3 inflammasome activation via targeting Forkhead box O 1.
Li Y, Yao N, Gao Y, Wang Y, Bai L, Xu J, Wang H
Bioengineered 2021 Dec;12(1):8555-8569
Bioengineered 2021 Dec;12(1):8555-8569
Long non-coding RNA LOC107985656 represses the proliferation of hepatocellular carcinoma cells through activation of the tumor-suppressive Hippo pathway.
Zeng Y, Xu Q, Xu N
Bioengineered 2021 Dec;12(1):7964-7974
Bioengineered 2021 Dec;12(1):7964-7974
Circular RNA circCRKL inhibits the proliferation of acute myeloid leukemia cells via the miR-196a-5p/miR-196b-5p/p27 axis.
Liu W, Cheng F
Bioengineered 2021 Dec;12(1):7704-7713
Bioengineered 2021 Dec;12(1):7704-7713
Impact of hepatocyte-specific deletion of staphylococcal nuclease and tudor domain containing 1 (SND1) on liver insulin resistance and acute liver failure of mice.
Zhao C, Cui X, Zhao Y, Qian B, Zhang N, Xin L, Ha C, Yang J, Wang X, Gao X
Bioengineered 2021 Dec;12(1):7360-7375
Bioengineered 2021 Dec;12(1):7360-7375
Dynamic Dissection of Dynein and Kinesin-1 Cooperatively Mediated Intercellular Transport of Porcine Epidemic Diarrhea Coronavirus along Microtubule Using Single Virus Tracking.
Hou W, Kang W, Li Y, Shan Y, Wang S, Liu F
Virulence 2021 Dec;12(1):615-629
Virulence 2021 Dec;12(1):615-629
α-Actinin1 promotes tumorigenesis and epithelial-mesenchymal transition of gastric cancer via the AKT/GSK3β/β-Catenin pathway.
Zhang S, Wang J, Chen T, Wang J, Wang Y, Yu Z, Zhao K, Zheng K, Chen Y, Wang Z, Li B, Wang C, Huang W, Fu Z, Chen J
Bioengineered 2021 Dec;12(1):5688-5704
Bioengineered 2021 Dec;12(1):5688-5704
T-box transcription factor TBX1, targeted by microRNA-6727-5p, inhibits cell growth and enhances cisplatin chemosensitivity of cervical cancer cells through AKT and MAPK pathways.
Liu H, Song M, Sun X, Zhang X, Miao H, Wang Y
Bioengineered 2021 Dec;12(1):565-577
Bioengineered 2021 Dec;12(1):565-577
The tumor-suppressive effects of alpha-ketoglutarate-dependent dioxygenase FTO via N6-methyladenosine RNA methylation on bladder cancer patients.
Yi W, Yu Y, Li Y, Yang J, Gao S, Xu L
Bioengineered 2021 Dec;12(1):5323-5333
Bioengineered 2021 Dec;12(1):5323-5333
Activation of NLR family, domain of pyrin containing 3 inflammasome by nitrous oxide through thioredoxin-interacting protein to induce nerve cell injury.
Liu W, Zhang G, Sun B, Wang S, Lu Y, Xie H
Bioengineered 2021 Dec;12(1):4768-4779
Bioengineered 2021 Dec;12(1):4768-4779
Danshensu alleviates bleomycin-induced pulmonary fibrosis by inhibiting lung fibroblast-to-myofibroblast transition via the MEK/ERK signaling pathway.
Liu H, Zhang X, Shao Y, Lin X, Dong F, Liu X
Bioengineered 2021 Dec;12(1):3113-3124
Bioengineered 2021 Dec;12(1):3113-3124
Site-specific SUMOylation of viral polymerase processivity factor: a way of localizingtoND10 subnuclear domains for restricted and self-controlled reproduction of herpesvirus.
Lai S, Xu M, Wang Y, Li R, Xia C, Xia S, Chen J
Virulence 2021 Dec;12(1):2883-2901
Virulence 2021 Dec;12(1):2883-2901
MicroRNA-146b-3p regulates the dysfunction of vascular smooth muscle cells via repressing phosphoinositide-3 kinase catalytic subunit gamma.
Zhuang X, Gao F, Shi L, Liu W, Wang W, He X, Gao Y
Bioengineered 2021 Dec;12(1):2627-2638
Bioengineered 2021 Dec;12(1):2627-2638
Long non-coding RNA (lncRNA) PGM5P4-AS1 inhibits lung cancer progression by up-regulating leucine zipper tumor suppressor (LZTS3) through sponging microRNA miR-1275.
Feng J, Li J, Qie P, Li Z, Xu Y, Tian Z
Bioengineered 2021 Dec;12(1):196-207
Bioengineered 2021 Dec;12(1):196-207
Catalpol ameliorates psoriasis-like phenotypes via SIRT1 mediated suppression of NF-κB and MAPKs signaling pathways.
Liu A, Zhang B, Zhao W, Tu Y, Wang Q, Li J
Bioengineered 2021 Dec;12(1):183-195
Bioengineered 2021 Dec;12(1):183-195
A novel circular RNA (hsa_circ_0059930)-mediated miRNA-mRNA axis in the lipopolysaccharide-induced acute lung injury model of MRC-5 cells.
Han J, Li S, Feng Y, He Y, Hong W, Ye Z
Bioengineered 2021 Dec;12(1):1739-1751
Bioengineered 2021 Dec;12(1):1739-1751
Integrin β3 overexpression contributes to podocyte injury through inhibiting RhoA/YAP signaling pathway.
Li Z, Lian Z, Ma J, Zhang L, Lian X, Liu S, Xie J, Feng Z, Lin T, Zhang H, Liang X
Bioengineered 2021 Dec;12(1):1138-1149
Bioengineered 2021 Dec;12(1):1138-1149
Long intergenic noncoding RNA00265 promotes proliferation of gastric cancer via the microRNA-144-3p/Chromobox 4 axis.
Yang Z, OuYang X, Zheng L, Dai L, Luo W
Bioengineered 2021 Dec;12(1):1012-1025
Bioengineered 2021 Dec;12(1):1012-1025
Tyrosine kinase nonreceptor 1 (TNK1) knockdown ameliorates hemorrhage shock-induced kidney injury via inhibiting macrophage M1 polarization.
Tang M, Cai J, Wang Y, Huan Z, Yao H, Xu C, Ge X, Song S
3 Biotech 2021 Dec;11(12):501
3 Biotech 2021 Dec;11(12):501
Spatiotemporal regulation of JAZ4 expression and splicing contribute to ethylene- and auxin-mediated responses in Arabidopsis roots.
DeMott L, Oblessuc PR, Pierce A, Student J, Melotto M
The Plant journal : for cell and molecular biology 2021 Dec;108(5):1266-1282
The Plant journal : for cell and molecular biology 2021 Dec;108(5):1266-1282
Veratric acid alleviates liver ischemia/reperfusion injury by activating the Nrf2 signaling pathway.
Yu Q, Chen S, Tang H, Zhang X, Tao R, Yan Z, Shi J, Guo W, Zhang S
International immunopharmacology 2021 Dec;101(Pt B):108294
International immunopharmacology 2021 Dec;101(Pt B):108294
The impact of tobacco exposure on tumor microenvironment and prognosis in lung adenocarcinoma by integrative analysis of multi-omics data.
Lu X, Ma L, Yin X, Ji H, Qian Y, Zhong S, Yan A, Zhang Y
International immunopharmacology 2021 Dec;101(Pt B):108253
International immunopharmacology 2021 Dec;101(Pt B):108253
Sulfiredoxin-1 protects retinal ganglion cells from high glucose-induced oxidative stress and inflammatory injury by potentiating Nrf2 signaling via the Akt/GSK-3β pathway.
Zhu F, Shao J, Tian Y, Xu Z
International immunopharmacology 2021 Dec;101(Pt B):108221
International immunopharmacology 2021 Dec;101(Pt B):108221
Topoisomerase 2 inhibitor etoposide promotes interleukin-10 production in LPS-induced macrophages via upregulating transcription factor Maf and activating PI3K/Akt pathway.
Zhang J, Zhao H, Feng Y, Xu X, Yang Y, Zhang P, Lu Z, Zhang T
International immunopharmacology 2021 Dec;101(Pt A):108264
International immunopharmacology 2021 Dec;101(Pt A):108264
Aggregation-Induced Emission (AIE) Nanoparticles-Assisted NIR-II Fluorescence Imaging-Guided Diagnosis and Surgery for Inflammatory Bowel Disease (IBD).
Fan X, Xia Q, Zhang Y, Li Y, Feng Z, Zhou J, Qi J, Tang BZ, Qian J, Lin H
Advanced healthcare materials 2021 Dec;10(24):e2101043
Advanced healthcare materials 2021 Dec;10(24):e2101043
Pak2 reduction induces a failure of early embryonic development in mice.
Zeng J, Liu N, Yang Y, Cheng Y, Li Y, Guo X, Luo Q, Zhu L, Guan H, Song B, Sun X
Reproductive biology and endocrinology : RB&E 2021 Dec 9;19(1):181
Reproductive biology and endocrinology : RB&E 2021 Dec 9;19(1):181
Artesunate treatment ameliorates ultraviolet irradiation-driven skin photoaging via increasing β-catenin expression.
Tian L, Ke D, Hong Y, Zhang C, Tian D, Chen L, Zhan L, Zong S
Aging 2021 Dec 9;13(23):25325-25341
Aging 2021 Dec 9;13(23):25325-25341
NuMA regulates mitotic spindle assembly, structural dynamics and function via phase separation.
Sun M, Jia M, Ren H, Yang B, Chi W, Xin G, Jiang Q, Zhang C
Nature communications 2021 Dec 9;12(1):7157
Nature communications 2021 Dec 9;12(1):7157
HOPX Plays a Critical Role in Antiretroviral Drugs Induced Epigenetic Modification and Cardiac Hypertrophy.
Kashyap S, Rabbani M, de Lima I, Kondrachuk O, Patel R, Shafiei MS, Mukker A, Rajakumar A, Gupta MK
Cells 2021 Dec 8;10(12)
Cells 2021 Dec 8;10(12)
Uncovering a conserved vulnerability site in SARS-CoV-2 by a human antibody.
Li T, Cai H, Zhao Y, Li Y, Lai Y, Yao H, Liu LD, Sun Z, van Vlissingen MF, Kuiken T, GeurtsvanKessel CH, Zhang N, Zhou B, Lu L, Gong Y, Qin W, Mondal M, Duan B, Xu S, Richard AS, Raoul H, Chen J, Xu C, Wu L, Zhou H, Huang Z, Zhang X, Li J, Wang Y, Bi Y, Rockx B, Chen J, Meng FL, Lavillette D, Li D
EMBO molecular medicine 2021 Dec 7;13(12):e14544
EMBO molecular medicine 2021 Dec 7;13(12):e14544
miR-140-3p enhanced the osteo/odontogenic differentiation of DPSCs via inhibiting KMT5B under hypoxia condition.
Zheng H, Wang N, Li L, Ge L, Jia H, Fan Z
International journal of oral science 2021 Dec 7;13(1):41
International journal of oral science 2021 Dec 7;13(1):41
RND3 attenuates oxidative stress and vascular remodeling in spontaneously hypertensive rat via inhibiting ROCK1 signaling.
Wu N, Zheng F, Li N, Han Y, Xiong XQ, Wang JJ, Chen Q, Li YH, Zhu GQ, Zhou YB
Redox biology 2021 Dec 6;48:102204
Redox biology 2021 Dec 6;48:102204
(20S) Ginsenoside Rh2 Exerts Its Anti-Tumor Effect by Disrupting the HSP90A-Cdc37 System in Human Liver Cancer Cells.
Chen C, Wang YS, Zhang ET, Li GA, Liu WY, Li Y, Jin YH
International journal of molecular sciences 2021 Dec 6;22(23)
International journal of molecular sciences 2021 Dec 6;22(23)
Glucocorticoid receptor regulates PD-L1 and MHC-I in pancreatic cancer cells to promote immune evasion and immunotherapy resistance.
Deng Y, Xia X, Zhao Y, Zhao Z, Martinez C, Yin W, Yao J, Hang Q, Wu W, Zhang J, Yu Y, Xia W, Yao F, Zhao D, Sun Y, Ying H, Hung MC, Ma L
Nature communications 2021 Dec 6;12(1):7041
Nature communications 2021 Dec 6;12(1):7041
Berberrubine attenuates potassium oxonate- and hypoxanthine-induced hyperuricemia by regulating urate transporters and JAK2/STAT3 signaling pathway.
Lin G, Yu Q, Xu L, Huang Z, Mai L, Jiang L, Su Z, Xie J, Li Y, Liu Y, Lin Z, Chen J
European journal of pharmacology 2021 Dec 5;912:174592
European journal of pharmacology 2021 Dec 5;912:174592
Ultrasound triggered topical delivery of Bmp7 mRNA for white fat browning induction via engineered smart exosomes.
Guo Y, Wan Z, Zhao P, Wei M, Liu Y, Bu T, Sun W, Li Z, Yuan L
Journal of nanobiotechnology 2021 Dec 4;19(1):402
Journal of nanobiotechnology 2021 Dec 4;19(1):402
Efficient induction of proximity-dependent labelling by biotin feeding in BMAL1-BioID knock-in mice.
Murata K, Mimura A, Suzuki H, Mikami N, Hamada Y, Kato K, Iki N, Ishida M, Daitoku Y, Tanimoto Y, Okiyoneda T, Fujiyama T, Dinh TTH, Mizuno S, Sugiyama F
Journal of biochemistry 2021 Dec 4;170(4):453-461
Journal of biochemistry 2021 Dec 4;170(4):453-461
Hepatoprotective effect of genistein against dimethylnitrosamine-induced liver fibrosis in rats by regulating macrophage functional properties and inhibiting the JAK2/STAT3/SOCS3 signaling pathway.
Xu Y, Zhang D, Yang H, Liu Y, Zhang L, Zhang C, Chen G, Hu Y, Chen J, Zhang H, Mu Y, Liu P, Liu W
Frontiers in bioscience (Landmark edition) 2021 Dec 30;26(12):1572-1584
Frontiers in bioscience (Landmark edition) 2021 Dec 30;26(12):1572-1584
Initiation of oogenesis and meiosis in the fetal ovary depends on Dennd1a-mediated production of Wnt5a and retinoic acid from the somatic niches.
Shi J, Niu Q, Gao Q, Fu J, Ma J
Frontiers in bioscience (Landmark edition) 2021 Dec 30;26(12):1513-1524
Frontiers in bioscience (Landmark edition) 2021 Dec 30;26(12):1513-1524
USP30-AS1 contributes to mitochondrial quality control in glioblastoma cells.
Wang N, Li J, Xin Q, Xu N
Biochemical and biophysical research communications 2021 Dec 3;581:31-37
Biochemical and biophysical research communications 2021 Dec 3;581:31-37
LRRC4 mediates the formation of circular RNA CD44 to inhibitGBM cell proliferation.
Feng J, Ren X, Fu H, Li D, Chen X, Zu X, Liu Q, Wu M
Molecular therapy. Nucleic acids 2021 Dec 3;26:473-487
Molecular therapy. Nucleic acids 2021 Dec 3;26:473-487
The RNA binding protein QKI5 suppresses ovarian cancer via downregulating transcriptional coactivator TAZ.
Liu T, Yang Y, Xie Z, Luo Q, Yang D, Liu X, Zhao H, Wei Q, Liu Y, Li L, Wang Y, Wang F, Yu J, Xu J, Yu J, Yi P
Molecular therapy. Nucleic acids 2021 Dec 3;26:388-400
Molecular therapy. Nucleic acids 2021 Dec 3;26:388-400
Integration of transcriptome and proteome profiles in placenta accreta reveals trophoblast over-migration as the underlying pathogenesis.
Li N, Hou R, Liu C, Yang T, Qiao C, Wei J
Clinical proteomics 2021 Dec 29;18(1):31
Clinical proteomics 2021 Dec 29;18(1):31
Loss-of-function missense variant of AKAP4 induced male infertility through reduced interaction with QRICH2 during sperm flagella development.
Zhang G, Li D, Tu C, Meng L, Tan Y, Ji Z, Cheng J, Lu G, Lin G, Zhang H, Sun J, Wang M, Du J, Xu W
Human molecular genetics 2021 Dec 27;31(2):219-231
Human molecular genetics 2021 Dec 27;31(2):219-231
TdIF1-LSD1 Axis Regulates Epithelial-Mesenchymal Transition and Metastasis via Histone Demethylation of E-Cadherin Promoter in Lung Cancer.
Liu Q, Xiong J, Xu D, Hao N, Zhang Y, Sang Y, Wang Z, Zheng X, Min J, Diao H, Raphael J, Maleki Vareki S, Koropatnick J, Min W
International journal of molecular sciences 2021 Dec 27;23(1)
International journal of molecular sciences 2021 Dec 27;23(1)
MyD88 Mediates Colitis- and RANKL-Induced Microfold Cell Differentiation.
Li Y, Yang S, Huang X, Yang N, Wang C, Zhao J, Jing Z, Willems L, Liu G
Veterinary sciences 2021 Dec 24;9(1)
Veterinary sciences 2021 Dec 24;9(1)
SARS-CoV-2 Variants of Concern Infect the Respiratory Tract and Induce Inflammatory Response in Wild-Type Laboratory Mice.
Stone S, Rothan HA, Natekar JP, Kumari P, Sharma S, Pathak H, Arora K, Auroni TT, Kumar M
Viruses 2021 Dec 24;14(1)
Viruses 2021 Dec 24;14(1)
Rosmanol and Carnosol Synergistically Alleviate Rheumatoid Arthritis through Inhibiting TLR4/NF-κB/MAPK Pathway.
Li L, Pan Z, Ning D, Fu Y
Molecules (Basel, Switzerland) 2021 Dec 23;27(1)
Molecules (Basel, Switzerland) 2021 Dec 23;27(1)
6-Thioguanine Inhibits Herpes Simplex Virus 1 Infection of Eyes.
Chen D, Liu Y, Zhang F, You Q, Ma W, Wu J, Wu Z
Microbiology spectrum 2021 Dec 22;9(3):e0064621
Microbiology spectrum 2021 Dec 22;9(3):e0064621
Pan-cancer analysis of N4-acetylcytidine adaptor THUMPD1 as a predictor for prognosis and immunotherapy.
Li K, Liu J, Yang X, Tu Z, Huang K, Zhu X
Bioscience reports 2021 Dec 22;41(12)
Bioscience reports 2021 Dec 22;41(12)
miR-378d suppresses malignant phenotype of ESCC cells through AKT signaling.
Peng J, Shi S, Yu J, Liu J, Wei H, Song H, Wang S, Li Z, He S, Li L, Zhang H, Yan Z, Zhao R, Liu Y, Liu Y, Li J, Zhang R, Wang W
Cancer cell international 2021 Dec 22;21(1):702
Cancer cell international 2021 Dec 22;21(1):702
MIIP inhibits clear cell renal cell carcinoma proliferation and angiogenesis via negative modulation of the HIF-2α-CYR61 axis.
Yan F, Wang Q, Xia M, Ru Y, Hu W, Yan G, Xiong X, Zhang M, Wang J, Li Q, Zhang B, Wang H, Lin W, Wu G, Li X
Cancer biology & medicine 2021 Dec 22;19(6):818-35
Cancer biology & medicine 2021 Dec 22;19(6):818-35
Heat stress affects fetal brain and intestinal function associated with the alterations of placental barrier in late pregnant mouse.
Guo H, Yang Y, Qiao Y, He J, Yao W, Zheng W
Ecotoxicology and environmental safety 2021 Dec 20;227:112916
Ecotoxicology and environmental safety 2021 Dec 20;227:112916
Responses of JNK signaling pathway to the toxic dinoflagellate Prorocentrum lima in the mussel Perna viridis.
Lv JJ, Yuan KK, Lu MY, He ZB, Li HY, Yang WD
Ecotoxicology and environmental safety 2021 Dec 20;227:112905
Ecotoxicology and environmental safety 2021 Dec 20;227:112905
WTIP upregulates FOXO3a and induces apoptosis through PUMA in acute myeloid leukemia.
Zhu Y, Tong X, Wang Y, Lu X
Cell death & disease 2021 Dec 20;13(1):18
Cell death & disease 2021 Dec 20;13(1):18
USP3 promotes gastric cancer progression and metastasis by deubiquitination-dependent COL9A3/COL6A5 stabilisation.
Wu X, Wang H, Zhu D, Chai Y, Wang J, Dai W, Xiao Y, Tang W, Li J, Hong L, Pei M, Zhang J, Lin Z, Wang J, Li A, Liu S
Cell death & disease 2021 Dec 20;13(1):10
Cell death & disease 2021 Dec 20;13(1):10
Identification of key genes as predictive biomarkers for osteosarcoma metastasis using translational bioinformatics.
Ding FP, Tian JY, Wu J, Han DF, Zhao D
Cancer cell international 2021 Dec 2;21(1):640
Cancer cell international 2021 Dec 2;21(1):640
A machine learning pipeline revealing heterogeneous responses to drug perturbations on vascular smooth muscle cell spheroid morphology and formation.
Vaidyanathan K, Wang C, Krajnik A, Yu Y, Choi M, Lin B, Jang J, Heo SJ, Kolega J, Lee K, Bae Y
Scientific reports 2021 Dec 2;11(1):23285
Scientific reports 2021 Dec 2;11(1):23285
Anti-tumor effect of polysaccharide from Pleurotus ostreatus on H22 mouse Hepatoma ascites in-vivo and hepatocellular carcinoma in-vitro model.
Khinsar KH, Abdul S, Hussain A, Ud Din R, Lei L, Cao J, Abbasi M, Ur Rehman A, Farooqui N, Yi X, Min H, Wang L, Mintao Z
AMB Express 2021 Dec 2;11(1):160
AMB Express 2021 Dec 2;11(1):160
CLN7 is an organellar chloride channel regulating lysosomal function.
Wang Y, Zeng W, Lin B, Yao Y, Li C, Hu W, Wu H, Huang J, Zhang M, Xue T, Ren D, Qu L, Cang C
Science advances 2021 Dec 17;7(51):eabj9608
Science advances 2021 Dec 17;7(51):eabj9608
Generation and analysis of innovative genomically humanized knockin SOD1, TARDBP (TDP-43), and FUS mouse models.
Devoy A, Price G, De Giorgio F, Bunton-Stasyshyn R, Thompson D, Gasco S, Allan A, Codner GF, Nair RR, Tibbit C, McLeod R, Ali Z, Noda J, Marrero-Gagliardi A, Brito-Armas JM, Williams C, Öztürk MM, Simon M, O'Neill E, Bryce-Smith S, Harrison J, Atkins G, Corrochano S, Stewart M, Gilthorpe JD, Teboul L, Acevedo-Arozena A, Fisher EMC, Cunningham TJ
iScience 2021 Dec 17;24(12):103463
iScience 2021 Dec 17;24(12):103463
TCF4 and HuR mediated-METTL14 suppresses dissemination of colorectal cancer via N6-methyladenosine-dependent silencing of ARRDC4.
Wang H, Wei W, Zhang ZY, Liu Y, Shi B, Zhong W, Zhang HS, Fang X, Sun CL, Wang JB, Liu LX
Cell death & disease 2021 Dec 17;13(1):3
Cell death & disease 2021 Dec 17;13(1):3
Antiviral Activities of Carbazole Derivatives against Porcine Epidemic Diarrhea Virus In Vitro.
Chen Z, Chen J, Wei X, Hua H, Hu R, Ding N, Zhang J, Song D, Ye Y, Tang Y, Ding Z, Ke S
Viruses 2021 Dec 16;13(12)
Viruses 2021 Dec 16;13(12)
WITHDRAWN: Role of microRNA-19b-3p on osteoporosis after experimental spinal cord injury in rats.
Liu D, Lin Z, Huang Y, Qiu M
Archives of biochemistry and biophysics 2021 Dec 15;714:108805
Archives of biochemistry and biophysics 2021 Dec 15;714:108805
Lactoferrin Alleviates Acute Alcoholic Liver Injury by Improving Redox-Stress Response Capacity in Female C57BL/6J Mice.
Li D, Hu Z, He Q, Guo Y, Chong Y, Xu J, Qin L
Journal of agricultural and food chemistry 2021 Dec 15;69(49):14856-14867
Journal of agricultural and food chemistry 2021 Dec 15;69(49):14856-14867
A novel protoapigenone analog RY10-4 induces apoptosis of breast cancer cells by exacerbating mitochondrial Ca(2+) influx through mitochondrial calcium uniporter.
Xue P, Chen Q, Ren X, Liu D, Yang X
Toxicology and applied pharmacology 2021 Dec 15;433:115776
Toxicology and applied pharmacology 2021 Dec 15;433:115776
miR-126 regulates angiogenesis in myocardial ischemia by targeting HIF-1α.
Gao S, Gao H, Dai L, Han Y, Lei Z, Wang X, Chang H, Liu S, Wang Z, Tong H, Wu H
Experimental cell research 2021 Dec 15;409(2):112925
Experimental cell research 2021 Dec 15;409(2):112925
Deficiency of the Ribosomal Protein uL5 Leads to Significant Rearrangements of the Transcriptional and Translational Landscapes in Mammalian Cells.
Babaylova ES, Gopanenko AV, Tupikin AE, Kabilov MR, Malygin AA, Karpova GG
International journal of molecular sciences 2021 Dec 15;22(24)
International journal of molecular sciences 2021 Dec 15;22(24)
Synergistic anti-inflammatory activity of apigenin and curcumin co-encapsulated in caseins assessed with lipopolysaccharide-stimulated RAW 264.7 macrophages.
Hong S, Dia VP, Zhong Q
International journal of biological macromolecules 2021 Dec 15;193(Pt A):702-712
International journal of biological macromolecules 2021 Dec 15;193(Pt A):702-712
A Study on How Methionine Restriction Decreases the Body's Hepatic and Lipid Deposition in Rice Field Eel (Monopterus albus).
Hu Y, Cai M, Zhong H, Chu W, Hu Y
International journal of molecular sciences 2021 Dec 13;22(24)
International journal of molecular sciences 2021 Dec 13;22(24)
Effect of High Static Magnetic Fields on Biological Activities and Iron Metabolism in MLO-Y4 Osteocyte-like Cells.
Yang J, Zhang G, Li Q, Tang Q, Feng Y, Shang P, Zeng Y
Cells 2021 Dec 13;10(12)
Cells 2021 Dec 13;10(12)
Intermittent bolus feeding does not enhance protein synthesis, myonuclear accretion, or lean growth more than continuous feeding in a premature piglet model.
Rudar M, Naberhuis JK, Suryawan A, Nguyen HV, Stoll B, Style CC, Verla MA, Olutoye OO, Burrin DG, Fiorotto ML, Davis TA
American journal of physiology. Endocrinology and metabolism 2021 Dec 1;321(6):E737-E752
American journal of physiology. Endocrinology and metabolism 2021 Dec 1;321(6):E737-E752
Role of the hippo signaling pathway in the extracellular matrix degradation of chondrocytes induced by fluoride exposure.
Yu FF, Zuo J, Fu X, Gao MH, Sun L, Yu SY, Li Z, Zhou GY, Ba Y
Ecotoxicology and environmental safety 2021 Dec 1;225:112796
Ecotoxicology and environmental safety 2021 Dec 1;225:112796
Cypermethrin triggers YY1-mediated testosterone biosynthesis suppression.
Liu C, Qu J, Wu M, Huang X, Li L
Ecotoxicology and environmental safety 2021 Dec 1;225:112792
Ecotoxicology and environmental safety 2021 Dec 1;225:112792
Klotho ameliorated cognitive deficits in a temporal lobe epilepsy rat model by inhibiting ferroptosis.
Xiang T, Luo X, Zeng C, Li S, Ma M, Wu Y
Brain research 2021 Dec 1;1772:147668
Brain research 2021 Dec 1;1772:147668
Nicaraven inhibits TNFα-induced endothelial activation and inflammation through suppression of NF-κB signaling pathway.
Lin H, Wu X, Yang Y, Wang Z, Huang W, Wang LF, Liu QW, Guan XH, Deng KY, Li TS, Qian Y, Xin HB
Canadian journal of physiology and pharmacology 2021 Aug;99(8):803-811
Canadian journal of physiology and pharmacology 2021 Aug;99(8):803-811
Adipose-derived stem cells (ADSCs) inhibit the expression of anti-apoptosis proteins through up-regulation of ATF4 on breast cancer cells.
Ren J, Kong W, Lu F, Li Y
Annals of translational medicine 2021 Aug;9(16):1300
Annals of translational medicine 2021 Aug;9(16):1300
Glaucocalyxin A induces apoptosis and autophagy in tongue squamous cell carcinoma cells by regulating ROS.
Shi F, Xue D, Jiang Q, Qiu J
Cancer chemotherapy and pharmacology 2021 Aug;88(2):235-246
Cancer chemotherapy and pharmacology 2021 Aug;88(2):235-246
IL-10 ameliorates PM2.5-induced lung injury by activating the AMPK/SIRT1/PGC-1α pathway.
Zhang N, Li P, Lin H, Shuo T, Ping F, Su L, Chen G
Environmental toxicology and pharmacology 2021 Aug;86:103659
Environmental toxicology and pharmacology 2021 Aug;86:103659
Hsa-miR-34a-5p reverses multidrug resistance in gastric cancer cells by targeting the 3'-UTR of SIRT1 and inhibiting its expression.
Deng XJ, Zheng HL, Ke XQ, Deng M, Ma ZZ, Zhu Y, Cui YY
Cellular signalling 2021 Aug;84:110016
Cellular signalling 2021 Aug;84:110016
CircZNF208 enhances the sensitivity to X-rays instead of carbon-ions through the miR-7-5p /SNCA signal axis in non-small-cell lung cancer cells.
Liu B, Li H, Liu X, Li F, Chen W, Kuang Y, Zhao X, Li L, Yu B, Jin X, Li Q
Cellular signalling 2021 Aug;84:110012
Cellular signalling 2021 Aug;84:110012
Heat shock protein 90 inhibitor ameliorates pancreatic fibrosis by degradation of transforming growth factor-β receptor.
Peng YF, Lin H, Liu DC, Zhu XY, Huang N, Wei YX, Li L
Cellular signalling 2021 Aug;84:110001
Cellular signalling 2021 Aug;84:110001
The Regulation of Neutrophil Extracellular Trap-induced Tissue Damage by Human CD177.
Yoneyama T, Maeda A, Kogata S, Toyama C, Lo PC, Masahata K, Kamiyama M, Haneda T, Okamatu C, Eguchi H, Tazuke Y, Ueno T, Okuyama H, Miyagawa S
Transplantation direct 2021 Aug;7(8):e734
Transplantation direct 2021 Aug;7(8):e734
6-Shogaol from ginger shows anti-tumor effect in cervical carcinoma via PI3K/Akt/mTOR pathway.
Pei XD, He ZL, Yao HL, Xiao JS, Li L, Gu JZ, Shi PZ, Wang JH, Jiang LH
European journal of nutrition 2021 Aug;60(5):2781-2793
European journal of nutrition 2021 Aug;60(5):2781-2793
microRNA-4429-5p suppresses the malignant development of colon cancer by targeting matrix metalloproteinase 16.
Li W, Song Z, Jia N, Zhang C, Gao W, Wang L
In vitro cellular & developmental biology. Animal 2021 Aug;57(7):715-725
In vitro cellular & developmental biology. Animal 2021 Aug;57(7):715-725
ROBO2 hampers malignant biological behavior and predicts a better prognosis in pancreatic adenocarcinoma.
Ding C, Li Y, Wang S, Xing C, Chen L, Zhang H, Wang Y, Dai M
Scandinavian journal of gastroenterology 2021 Aug;56(8):955-964
Scandinavian journal of gastroenterology 2021 Aug;56(8):955-964
Effect of electro-acupuncture at ST 36 on maternal food restriction-induced lung phenotype in rat offspring.
Mou Q, Ji B, Zhao G, Liu Y, Sakurai R, Xie Y, Zhang Q, Dai J, Lu Y, Ge Y, Shi T, Xu S, Rehan VK
Pediatric pulmonology 2021 Aug;56(8):2537-2545
Pediatric pulmonology 2021 Aug;56(8):2537-2545
Comparison of the biological and functional characteristics of mesenchymal stem cells from intrahepatic and identical bone marrow.
Lai J, Jiang S, Shuai L, Zhang Y, Xia R, Chen Q, Bai L
Stem cell research 2021 Aug;55:102477
Stem cell research 2021 Aug;55:102477
Establishment of two homozygous CRISPR interference (CRISPRi) knock-in human induced pluripotent stem cell (hiPSC) lines for titratable endogenous gene repression.
Schoger E, Zimmermann WH, Cyganek L, Zelarayán LC
Stem cell research 2021 Aug;55:102473
Stem cell research 2021 Aug;55:102473
Base editing-mediated perturbation of endogenous PKM1/2 splicing facilitates isoform-specific functional analysis in vitro and in vivo.
Lin J, Wu S, Shen Q, Liu J, Huang S, Peng G, Qiao Y
Cell proliferation 2021 Aug;54(8):e13096
Cell proliferation 2021 Aug;54(8):e13096
Loss of microRNA-147 function alleviates synovial inflammation through ZNF148 in rheumatoid and experimental arthritis.
Jiang C, Wu X, Li X, Li M, Zhang W, Tao P, Xu J, Ren X, Mo L, Guo Y, Wang S, Geng M, Zhang F, Tian J, Zhu W, Meng L, Lu S
European journal of immunology 2021 Aug;51(8):2062-2073
European journal of immunology 2021 Aug;51(8):2062-2073
DJ-1 activates the noncanonical NF-κB pathway via interaction with Cezanne to inhibit the apoptosis and promote the proliferation of Ishikawa cells.
Zhu QZ, Liu HY, Zhao XY, Qiu LJ, Zhou TT, Wang XY, Chen HP, Xiao ZQ
Molecular biology reports 2021 Aug;48(8):6075-6083
Molecular biology reports 2021 Aug;48(8):6075-6083
Long noncoding RNA uc003pxg.1 regulates endothelial cell proliferation and migration via miR‑25‑5p in coronary artery disease.
Li P, Li Y, Chen L, Ma X, Yan X, Yan M, Qian B, Wang F, Xu J, Yin J, Xu G, Sun K
International journal of molecular medicine 2021 Aug;48(2)
International journal of molecular medicine 2021 Aug;48(2)
Increased AT(1) receptor expression mediates vasoconstriction leading to hypertension in Snx1(-/-) mice.
Liu C, Li X, Fu J, Chen K, Liao Q, Wang J, Chen C, Luo H, Jose PA, Yang Y, Yang J, Zeng C
Hypertension research : official journal of the Japanese Society of Hypertension 2021 Aug;44(8):906-917
Hypertension research : official journal of the Japanese Society of Hypertension 2021 Aug;44(8):906-917
Downregulation of glucose-6-phosphatase expression contributes to fluoxetine-induced hepatic steatosis.
Lu S, Ma Z, Gu Y, Li P, Chen Y, Bai M, Zhou H, Yang X, Jiang H
Journal of applied toxicology : JAT 2021 Aug;41(8):1232-1240
Journal of applied toxicology : JAT 2021 Aug;41(8):1232-1240
Chromium (VI) promotes EMT by regulating FLNA in BLCA.
Sheng F, Chen KX, Liu J, Li JX, Liang GH, Xu Y, Du E, Zhang ZH
Environmental toxicology 2021 Aug;36(8):1694-1701
Environmental toxicology 2021 Aug;36(8):1694-1701
Rearrangement of Actin Cytoskeleton by Zika Virus Infection Facilitates Blood-Testis Barrier Hyperpermeability.
Nie Y, Hui L, Guo M, Yang W, Huang R, Chen J, Wen X, Zhao M, Wu Y
Virologica Sinica 2021 Aug;36(4):692-705
Virologica Sinica 2021 Aug;36(4):692-705
Endothelial neuropilin-2 influences angiogenesis by regulating actin pattern development and α5-integrin-p-FAK complex recruitment to assembling adhesion sites.
Benwell CJ, Taylor JAGE, Robinson SD
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 Aug;35(8):e21679
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 Aug;35(8):e21679
Salidroside protects cardiac function in mice with diabetic cardiomyopathy via activation of mitochondrial biogenesis and SIRT3.
Li Y, Wei X, Liu SL, Zhao Y, Jin S, Yang XY
Phytotherapy research : PTR 2021 Aug;35(8):4579-4591
Phytotherapy research : PTR 2021 Aug;35(8):4579-4591
RNA m(6)A modification orchestrates a LINE-1-host interaction that facilitates retrotransposition and contributes to long gene vulnerability.
Xiong F, Wang R, Lee JH, Li S, Chen SF, Liao Z, Hasani LA, Nguyen PT, Zhu X, Krakowiak J, Lee DF, Han L, Tsai KL, Liu Y, Li W
Cell research 2021 Aug;31(8):861-885
Cell research 2021 Aug;31(8):861-885
Inhibition of hepatitis E virus replication by zinc-finger antiviral Protein synergizes with IFN-β.
Yu W, Ji H, Long F, Chen S, He Q, Xia Y, Cong C, Yang C, Wei D, Huang F
Journal of viral hepatitis 2021 Aug;28(8):1219-1229
Journal of viral hepatitis 2021 Aug;28(8):1219-1229
GINS2 promotes EMT in pancreatic cancer via specifically stimulating ERK/MAPK signaling.
Huang L, Chen S, Fan H, Ji D, Chen C, Sheng W
Cancer gene therapy 2021 Aug;28(7-8):839-849
Cancer gene therapy 2021 Aug;28(7-8):839-849
Lys694Arg polymorphism leads to blunted responses to LPS by interfering TLR4 with recruitment of MyD88.
Yang Y, Hu Y, Zhou Y, Liang T, Tang H, Ju H, Shi Q, Fang H
Innate immunity 2021 Aug;27(6):483-492
Innate immunity 2021 Aug;27(6):483-492
Genotype-dependent epigenetic regulation of DLGAP2 in alcohol use and dependence.
Meng W, Sjöholm LK, Kononenko O, Tay N, Zhang D, Sarkisyan D, Geske JR, Ing A, Qiu W, Watanabe H, Almamoun R, Frieling H, Bleich S, Cui D, Biernacka JM, Mayfield RD, Dang Y, Karpyak VM, Schumann G, IMAGEN Consortium, Bakalkin G, Ekström TJ, Rüegg J, Liu Y
Molecular psychiatry 2021 Aug;26(8):4367-4382
Molecular psychiatry 2021 Aug;26(8):4367-4382
Helicobacter pylori induces gastric cancer via down-regulating miR-375 to inhibit dendritic cell maturation.
Zhang Z, Chen S, Fan M, Ruan G, Xi T, Zheng L, Guo L, Ye F, Xing Y
Helicobacter 2021 Aug;26(4):e12813
Helicobacter 2021 Aug;26(4):e12813
Vimentin rearrangement by phosphorylation is beneficial for porcine reproductive and respiratory syndrome virus replication in vitro.
Zheng XX, Li R, Qiao S, Chen XX, Zhang L, Lu Q, Xing G, Zhou EM, Zhang G
Veterinary microbiology 2021 Aug;259:109133
Veterinary microbiology 2021 Aug;259:109133
EGCG synergizes the therapeutic effect of irinotecan through enhanced DNA damage in human colorectal cancer cells.
Wu W, Dong J, Gou H, Geng R, Yang X, Chen D, Xiang B, Zhang Z, Ren S, Chen L, Liu J
Journal of cellular and molecular medicine 2021 Aug;25(16):7913-7921
Journal of cellular and molecular medicine 2021 Aug;25(16):7913-7921
Ring finger protein 19A is overexpressed in non-small cell lung cancer and mediates p53 ubiquitin-degradation to promote cancer growth.
Cheng Y, Hu Y, Wang H, Zhao Z, Jiang X, Zhang Y, Zhang J, Tong Y, Qiu X
Journal of cellular and molecular medicine 2021 Aug;25(16):7796-7808
Journal of cellular and molecular medicine 2021 Aug;25(16):7796-7808
Propofol attenuates renal ischemia/reperfusion injury by regulating the MALAT1/miR-126-5p axis.
Li X, Zhang Z, Li A, Hu Y
The journal of gene medicine 2021 Aug;23(8):e3349
The journal of gene medicine 2021 Aug;23(8):e3349
ASTE1 promotes shieldin-complex-mediated DNA repair by attenuating end resection.
Zhao F, Kim W, Gao H, Liu C, Zhang Y, Chen Y, Deng M, Zhou Q, Huang J, Hu Q, Chen SH, Nowsheen S, Kloeber JA, Qin B, Yin P, Tu X, Guo G, Qin S, Zhang C, Gao M, Luo K, Liu Y, Lou Z, Yuan J
Nature cell biology 2021 Aug;23(8):894-904
Nature cell biology 2021 Aug;23(8):894-904
Decreased TMEM40 expression is associated with malignant behavior of cutaneous squamous cell carcinoma and inhibits tumor progression.
Yu L, Liu J, Zhang TD, Zheng XF, Luo DL, Zhu WL, Qiu XW, Guo LL
Oncology letters 2021 Aug;22(2):606
Oncology letters 2021 Aug;22(2):606
Indoleamine 2,3-Dioxygenase 1 (IDO1) Promotes Cardiac Hypertrophy via a PI3K-AKT-mTOR-Dependent Mechanism.
Liu Y, Li S, Gao Z, Li S, Tan Q, Li Y, Wang D, Wang Q
Cardiovascular toxicology 2021 Aug;21(8):655-668
Cardiovascular toxicology 2021 Aug;21(8):655-668
A γ-adducin cleavage fragment induces neurite deficits and synaptic dysfunction in Alzheimer's disease.
Xiong M, Zou L, Meng L, Zhang X, Tian Y, Zhang G, Yang J, Chen G, Xiong J, Ye K, Zhang Z
Progress in neurobiology 2021 Aug;203:102074
Progress in neurobiology 2021 Aug;203:102074
Investigating the nature of active forces in tissues reveals how contractile cells can form extensile monolayers.
Balasubramaniam L, Doostmohammadi A, Saw TB, Narayana GHNS, Mueller R, Dang T, Thomas M, Gupta S, Sonam S, Yap AS, Toyama Y, Mège RM, Yeomans JM, Ladoux B
Nature materials 2021 Aug;20(8):1156-1166
Nature materials 2021 Aug;20(8):1156-1166
MiR-532-3p suppresses cell viability, migration and invasion of clear cell renal cell carcinoma through targeting TROAP.
Gao B, Wang L, Zhang Y, Zhang N, Han M, Liu H, Sun D, Liu Y
Cell cycle (Georgetown, Tex.) 2021 Aug;20(16):1578-1588
Cell cycle (Georgetown, Tex.) 2021 Aug;20(16):1578-1588
Nitazoxanide impairs mitophagy flux through ROS-mediated mitophagy initiation and lysosomal dysfunction in bladder cancer.
Sun H, Ou T, Hu J, Yang Z, Lei Q, Li Y, Wang G, Li Y, Wu K, Wang S, Wu S
Biochemical pharmacology 2021 Aug;190:114588
Biochemical pharmacology 2021 Aug;190:114588
Depletion of CIP2A inhibits the proliferation, migration, invasion and epithelial-mesenchymal transition of glioma cells.
Xu Z, Chen X, Hegazy AM, Zhang S, Liu X, Tian J, Wu J, Shi F, Li L, Niu X, Pu J
Brain research bulletin 2021 Aug;173:14-21
Brain research bulletin 2021 Aug;173:14-21
The role of circTmeff-1 in incubation of context-induced morphine craving.
Yu H, Xie B, Zhang J, Luo Y, Galaj E, Zhang X, Shen Q, Liu Y, Cong B, Wen D, Ma C
Pharmacological research 2021 Aug;170:105722
Pharmacological research 2021 Aug;170:105722
High-throughput screening and genome-wide analyses of 44 anticancer drugs in the 1000 Genomes cell lines reveals an association of the NQO1 gene with the response of multiple anticancer drugs.
Akhtari FS, Green AJ, Small GW, Havener TM, House JS, Roell KR, Reif DM, McLeod HL, Wiltshire T, Motsinger-Reif AA
PLoS genetics 2021 Aug;17(8):e1009732
PLoS genetics 2021 Aug;17(8):e1009732
PtdIns4P restriction by hydrolase SAC1 decides specific fusion of autophagosomes with lysosomes.
Zhang H, Zhou J, Xiao P, Lin Y, Gong X, Liu S, Xu Q, Wang M, Ren H, Lu M, Wang Y, Zhu J, Xie Z, Li H, Lu K
Autophagy 2021 Aug;17(8):1907-1917
Autophagy 2021 Aug;17(8):1907-1917
Classical swine fever virus infection suppresses claudin-1 expression to facilitate its replication in PK-15 cells.
Wang X, Yang Y, Yang X, Liu X, Wang X, Gao L, Yang C, Lan R, Bi J, Zhao Q, Yang G, Wang J, Lin Y, Liu J, Yin G
Microbial pathogenesis 2021 Aug;157:105012
Microbial pathogenesis 2021 Aug;157:105012
Stabilization of Nrf2 leading to HO-1 activation protects against zinc oxide nanoparticles-induced endothelial cell death.
Zhang L, Zou L, Jiang X, Cheng S, Zhang J, Qin X, Qin Z, Chen C, Zou Z
Nanotoxicology 2021 Aug;15(6):779-797
Nanotoxicology 2021 Aug;15(6):779-797
Bavachin enhances NLRP3 inflammasome activation induced by ATP or nigericin and causes idiosyncratic hepatotoxicity.
Qin N, Xu G, Wang Y, Zhan X, Gao Y, Wang Z, Fu S, Shi W, Hou X, Wang C, Li R, Liu Y, Wang J, Zhao H, Xiao X, Bai Z
Frontiers of medicine 2021 Aug;15(4):594-607
Frontiers of medicine 2021 Aug;15(4):594-607
Expression of ISL1 and its partners in prostate cancer progression and neuroendocrine differentiation.
Alshalalfa M, Abou-Ouf H, Davicioni E, Karnes RJ, Alhajj R, Bismar TA
Journal of cancer research and clinical oncology 2021 Aug;147(8):2223-2231
Journal of cancer research and clinical oncology 2021 Aug;147(8):2223-2231
MD2 blockage prevents the migration and invasion of hepatocellular carcinoma cells via inhibition of the EGFR signaling pathway.
Qi Y, Fang Q, Li Q, Ding H, Shu Q, Hu Y, Xin W, Fang L
Journal of gastrointestinal oncology 2021 Aug;12(4):1873-1883
Journal of gastrointestinal oncology 2021 Aug;12(4):1873-1883
miR-744-5p suppresses tumor proliferation and metastasis by targeting transforming growth factor-beta 1 (TGF-β1) in hepatocellular carcinoma (HCC).
Huang W, Chen Q, Dai J, Zhang Y, Yi Y, Wei X, Wu Z
Journal of gastrointestinal oncology 2021 Aug;12(4):1811-1822
Journal of gastrointestinal oncology 2021 Aug;12(4):1811-1822
XPA serves as an autophagy and apoptosis inducer by suppressing hepatocellular carcinoma in a PI3K/Akt/mTOR dependent manner.
Deng Y, Chen QS, Huang WF, Dai JW, Wu ZJ
Journal of gastrointestinal oncology 2021 Aug;12(4):1797-1810
Journal of gastrointestinal oncology 2021 Aug;12(4):1797-1810
Vitamin D alleviates hypoxia/reoxygenation-induced injury of human trophoblast HTR-8 cells by activating autophagy.
Pi Y, Tian X, Ma J, Zhang H, Huang X
Placenta 2021 Aug;111:10-18
Placenta 2021 Aug;111:10-18
Follicle-stimulating hormone worsens osteoarthritis by causing inflammation and chondrocyte dedifferentiation.
Huan Z, Wang Y, Zhang M, Zhang X, Liu Y, Kong L, Xu J
FEBS open bio 2021 Aug;11(8):2292-2303
FEBS open bio 2021 Aug;11(8):2292-2303
Renoprotective effects of levosimendan on acute kidney injury following cardiac arrest via anti-inflammation, anti-apoptosis, and ERK activation.
Tian L, Wang S, Zhao L, Lu X, Zhu C, Gong H, Yang W
FEBS open bio 2021 Aug;11(8):2236-2244
FEBS open bio 2021 Aug;11(8):2236-2244
TRIM27 contributes to glomerular endothelial cell injury in lupus nephritis by mediating the FoxO1 signaling pathway.
Liu J, Xu J, Huang J, Gu C, Liu Q, Zhang W, Gao F, Tian Y, Miao X, Zhu Z, Jia B, Tian Y, Wu L, Zhao H, Feng X, Liu S
Laboratory investigation; a journal of technical methods and pathology 2021 Aug;101(8):983-997
Laboratory investigation; a journal of technical methods and pathology 2021 Aug;101(8):983-997
Paraquat but not diquat induces TGF-β expression and thus activates calcium-NFAT axis for epithelial-mesenchymal transition.
Yang W, Ma X, Zhu Y, Meng X, Tian R, Yang Z
Toxicology research 2021 Aug;10(4):733-741
Toxicology research 2021 Aug;10(4):733-741
AHR mediates the aflatoxin B1 toxicity associated with hepatocellular carcinoma.
Zhu Q, Ma Y, Liang J, Wei Z, Li M, Zhang Y, Liu M, He H, Qu C, Cai J, Wang X, Zeng Y, Jiao Y
Signal transduction and targeted therapy 2021 Aug 9;6(1):299
Signal transduction and targeted therapy 2021 Aug 9;6(1):299
Bcl-2-associated transcription factor 1 Ser290 phosphorylation mediates DNA damage response and regulates radiosensitivity in gastric cancer.
Liu J, Li J, Sun Z, Duan Y, Wang F, Wei G, Yang JH
Journal of translational medicine 2021 Aug 9;19(1):339
Journal of translational medicine 2021 Aug 9;19(1):339
Autophagy-associated circular RNA hsa_circ_0007813 modulates human bladder cancer progression via hsa-miR-361-3p/IGF2R regulation.
Zhang Z, Mou Z, Xu C, Wu S, Dai X, Chen X, Ou Y, Chen Y, Yang C, Jiang H
Cell death & disease 2021 Aug 7;12(8):778
Cell death & disease 2021 Aug 7;12(8):778
MiR-133a-3p inhibits scar formation in scalded mice and suppresses the proliferation and migration of scar derived-fibroblasts by targeting connective tissue growth factor.
Hirman AR, Du L, Cheng S, Zheng H, Duo L, Zhai Q, Xu J
Experimental animals 2021 Aug 6;70(3):322-332
Experimental animals 2021 Aug 6;70(3):322-332
miR-145-5p attenuates inflammatory response and apoptosis in myocardial ischemia-reperfusion injury by inhibiting (NADPH) oxidase homolog 1.
Tan L, Liu L, Yao J, Piao C
Experimental animals 2021 Aug 6;70(3):311-321
Experimental animals 2021 Aug 6;70(3):311-321
Cofilin-1 promotes fibrocyte differentiation and contributes to pulmonary fibrosis.
Guo W, Guo T, Zhou Q, Long Y, Luo M, Shen Q, Duan W, Ouyang X, Peng H
Biochemical and biophysical research communications 2021 Aug 6;565:43-49
Biochemical and biophysical research communications 2021 Aug 6;565:43-49
Human CD4+ T-Cell Clone Expansion Leads to the Expression of the Cysteine Peptidase Inhibitor Cystatin F.
Perišić Nanut M, Pawelec G, Kos J
International journal of molecular sciences 2021 Aug 5;22(16)
International journal of molecular sciences 2021 Aug 5;22(16)
RNA-binding protein RBM47 stabilizes IFNAR1 mRNA to potentiate host antiviral activity.
Wang K, Huang C, Jiang T, Chen Z, Xue M, Zhang Q, Zhang J, Dai J
EMBO reports 2021 Aug 4;22(8):e52205
EMBO reports 2021 Aug 4;22(8):e52205
PKCε controls the fusion of secretory vesicles in mast cells in a phosphatidic acid-dependent mode.
Serrano-López EM, López-Martínez D, Gómez-Fernández JC, Egea-Jiménez AL, Corbalán-García S
International journal of biological macromolecules 2021 Aug 31;185:377-389
International journal of biological macromolecules 2021 Aug 31;185:377-389
Methyltransferase-like 3 Modulates Severe Acute Respiratory Syndrome Coronavirus-2 RNA N6-Methyladenosine Modification and Replication.
Zhang X, Hao H, Ma L, Zhang Y, Hu X, Chen Z, Liu D, Yuan J, Hu Z, Guan W
mBio 2021 Aug 31;12(4):e0106721
mBio 2021 Aug 31;12(4):e0106721
Pericentromeric noncoding RNA changes DNA binding of CTCF and inflammatory gene expression in senescence and cancer.
Miyata K, Imai Y, Hori S, Nishio M, Loo TM, Okada R, Yang L, Nakadai T, Maruyama R, Fujii R, Ueda K, Jiang L, Zheng H, Toyokuni S, Sakata T, Shirahige K, Kojima R, Nakayama M, Oshima M, Nagayama S, Seimiya H, Hirota T, Saya H, Hara E, Takahashi A
Proceedings of the National Academy of Sciences of the United States of America 2021 Aug 31;118(35)
Proceedings of the National Academy of Sciences of the United States of America 2021 Aug 31;118(35)
UBE2T promotes autophagy via the p53/AMPK/mTOR signaling pathway in lung adenocarcinoma.
Zhu J, Ao H, Liu M, Cao K, Ma J
Journal of translational medicine 2021 Aug 30;19(1):374
Journal of translational medicine 2021 Aug 30;19(1):374
Enriched environment remedies cognitive dysfunctions and synaptic plasticity through NMDAR-Ca(2+)-Activin A circuit in chronic cerebral hypoperfusion rats.
Zhang X, Shi X, Wang J, Xu Z, He J
Aging 2021 Aug 30;13(16):20748-20761
Aging 2021 Aug 30;13(16):20748-20761
AEG-1 silencing attenuates M2-polarization of glioma-associated microglia/macrophages and sensitizes glioma cells to temozolomide.
Li J, Sun Y, Sun X, Zhao X, Ma Y, Wang Y, Zhang X
Scientific reports 2021 Aug 30;11(1):17348
Scientific reports 2021 Aug 30;11(1):17348
BGP-15 Inhibits Hyperglycemia-Aggravated VSMC Calcification Induced by High Phosphate.
Nagy A, Pethő D, Gesztelyi R, Juhász B, Balla G, Szilvássy Z, Balla J, Gáll T
International journal of molecular sciences 2021 Aug 26;22(17)
International journal of molecular sciences 2021 Aug 26;22(17)
Efficient intracellular delivery of proteins by a multifunctional chimaeric peptide in vitro and in vivo.
Yu S, Yang H, Li T, Pan H, Ren S, Luo G, Jiang J, Yu L, Chen B, Zhang Y, Wang S, Tian R, Zhang T, Zhang S, Chen Y, Yuan Q, Ge S, Zhang J, Xia N
Nature communications 2021 Aug 26;12(1):5131
Nature communications 2021 Aug 26;12(1):5131
Autophagy Inhibition Plays a Protective Role in Ferroptosis Induced by Alcohol via the p62-Keap1-Nrf2 Pathway.
Zhao Y, Lu J, Mao A, Zhang R, Guan S
Journal of agricultural and food chemistry 2021 Aug 25;69(33):9671-9683
Journal of agricultural and food chemistry 2021 Aug 25;69(33):9671-9683
SESN2 protects against denervated muscle atrophy through unfolded protein response and mitophagy.
Yang X, Xue P, Yuan M, Xu X, Wang C, Li W, Machens HG, Chen Z
Cell death & disease 2021 Aug 24;12(9):805
Cell death & disease 2021 Aug 24;12(9):805
Biallelic SYNE2 Missense Mutations Leading to Nesprin-2 Giant Hypo-Expression Are Associated with Intellectual Disability and Autism.
Young N, Asif M, Jackson M, Fernández-Mayoralas DM, de la Peña MJ, Calleja-Pérez B, Álvarez S, Hunter-Featherstone E, Noegel AA, Höhne W, Nürnberg P, Obara B, Hussain MS, Karakesisoglou I, Fernández-Jaén A
Genes 2021 Aug 24;12(9)
Genes 2021 Aug 24;12(9)
Ten-eleven translocation 1 mediated-DNA hydroxymethylation is required for myelination and remyelination in the mouse brain.
Zhang M, Wang J, Zhang K, Lu G, Liu Y, Ren K, Wang W, Xin D, Xu L, Mao H, Xing J, Gao X, Jin W, Berry K, Mikoshiba K, Wu S, Lu QR, Zhao X
Nature communications 2021 Aug 24;12(1):5091
Nature communications 2021 Aug 24;12(1):5091
Autophagic elimination of ribosomes during spermiogenesis provides energy for flagellar motility.
Lei Y, Zhang X, Xu Q, Liu S, Li C, Jiang H, Lin H, Kong E, Liu J, Qi S, Li H, Xu W, Lu K
Developmental cell 2021 Aug 23;56(16):2313-2328.e7
Developmental cell 2021 Aug 23;56(16):2313-2328.e7
Helicobacter urease suppresses cytotoxic CD8+ T-cell responses through activating Myh9-dependent induction of PD-L1.
Wu J, Zhu X, Guo X, Yang Z, Cai Q, Gu D, Luo W, Yuan C, Xiang Y
International immunology 2021 Aug 23;33(9):491-504
International immunology 2021 Aug 23;33(9):491-504
A single genetic locus controls both expression of DPEP1/CHMP1A and kidney disease development via ferroptosis.
Guan Y, Liang X, Ma Z, Hu H, Liu H, Miao Z, Linkermann A, Hellwege JN, Voight BF, Susztak K
Nature communications 2021 Aug 23;12(1):5078
Nature communications 2021 Aug 23;12(1):5078
Engineered basic fibroblast growth factor-overexpressing human umbilical cord-derived mesenchymal stem cells improve the proliferation and neuronal differentiation of endogenous neural stem cells and functional recovery of spinal cord injury by activating the PI3K-Akt-GSK-3β signaling pathway.
Huang F, Gao T, Wang W, Wang L, Xie Y, Tai C, Liu S, Cui Y, Wang B
Stem cell research & therapy 2021 Aug 21;12(1):468
Stem cell research & therapy 2021 Aug 21;12(1):468
Sodium valproate increases activity of the sirtuin pathway resulting in beneficial effects for spinocerebellar ataxia-3 in vivo.
Watchon M, Luu L, Robinson KJ, Yuan KC, De Luca A, Suddull HJ, Tym MC, Guillemin GJ, Cole NJ, Nicholson GA, Chung RS, Lee A, Laird AS
Molecular brain 2021 Aug 20;14(1):128
Molecular brain 2021 Aug 20;14(1):128
UHPLC-MS-based metabolomics and chemoinformatics study reveals the neuroprotective effect and chemical characteristic in Parkinson's disease mice after oral administration of Wen-Shen-Yang-Gan decoction.
Zhu G, Wang W, Chen C, Tang L, Liang Y, Zhang Z, Lu Y, Zhao Y
Aging 2021 Aug 2;13(15):19510-19528
Aging 2021 Aug 2;13(15):19510-19528
Kaempferol attenuates diquat-induced oxidative damage and apoptosis in intestinal porcine epithelial cells.
Jin Y, Zhai Z, Jia H, Lai J, Si X, Wu Z
Food & function 2021 Aug 2;12(15):6889-6899
Food & function 2021 Aug 2;12(15):6889-6899
Enhancer RNA m6A methylation facilitates transcriptional condensate formation and gene activation.
Lee JH, Wang R, Xiong F, Krakowiak J, Liao Z, Nguyen PT, Moroz-Omori EV, Shao J, Zhu X, Bolt MJ, Wu H, Singh PK, Bi M, Shi CJ, Jamal N, Li G, Mistry R, Jung SY, Tsai KL, Ferreon JC, Stossi F, Caflisch A, Liu Z, Mancini MA, Li W
Molecular cell 2021 Aug 19;81(16):3368-3385.e9
Molecular cell 2021 Aug 19;81(16):3368-3385.e9
Repurposing of glycine transport inhibitors for the treatment of erythropoietic protoporphyria.
Halloy F, Iyer PS, Ghidini A, Lysenko V, Barman-Aksözen J, Grubenmann CP, Jucker J, Wildner-Verhey van Wijk N, Ruepp MD, Minder EI, Minder AE, Schneider-Yin X, Theocharides APA, Schümperli D, Hall J
Cell chemical biology 2021 Aug 19;28(8):1221-1234.e6
Cell chemical biology 2021 Aug 19;28(8):1221-1234.e6
Gastrin exerts a protective effect against myocardial infarction via promoting angiogenesis.
Fu J, Tang Y, Zhang Z, Tong L, Yue R, Cai L
Molecular medicine (Cambridge, Mass.) 2021 Aug 19;27(1):90
Molecular medicine (Cambridge, Mass.) 2021 Aug 19;27(1):90
Infection with Human Papillomavirus 18 Promotes Alkylating Agent-Induced Malignant Transformation in a Human Esophageal Cell Line.
Zhang Y, Li Y, Pan E, Zhao C, Zhang H, Liu R, Wang S, Pu Y, Yin L
Chemical research in toxicology 2021 Aug 16;34(8):1866-1878
Chemical research in toxicology 2021 Aug 16;34(8):1866-1878
Proof of Gene Doping in a Mouse Model with a Human Erythropoietin Gene Transferred Using an Adenoviral Vector.
Sugasawa T, Nakano T, Fujita SI, Matsumoto Y, Ishihara G, Aoki K, Yanazawa K, Ono S, Tamai S, Manevich L, Ueda H, Ishibashi N, Tamai K, Kanki Y, Yoshida Y, Watanabe K, Takemasa T, Kawakami Y, Takekoshi K
Genes 2021 Aug 16;12(8)
Genes 2021 Aug 16;12(8)
Tubeimoside I protects against sepsis-induced cardiac dysfunction via SIRT3.
Cheng Z, Lv D, Luo M, Wang R, Guo Y, Yang X, Huang L, Li X, Li C, Shang FF, Huang B, Shen J, Luo S, Yan J
European journal of pharmacology 2021 Aug 15;905:174186
European journal of pharmacology 2021 Aug 15;905:174186
Silencing of RSPO1 mitigates obesity-related renal fibrosis in mice by deactivating Wnt/β-catenin pathway.
Su X, Zhou G, Tian M, Wu S, Wang Y
Experimental cell research 2021 Aug 15;405(2):112713
Experimental cell research 2021 Aug 15;405(2):112713
Long-term exposure to environmental level of phenanthrene causes adaptive immune response and fibrosis in mouse kidneys.
Ruan F, Wu L, Yin H, Fang L, Tang C, Huang S, Fang L, Zuo Z, He C, Huang J
Environmental pollution (Barking, Essex : 1987) 2021 Aug 15;283:117028
Environmental pollution (Barking, Essex : 1987) 2021 Aug 15;283:117028
Itpr1 regulates the formation of anterior eye segment tissues derived from neural crest cells.
Kinoshita A, Ohyama K, Tanimura S, Matsuda K, Kishino T, Negishi Y, Asahina N, Shiraishi H, Hosoki K, Tomiwa K, Ishihara N, Mishima H, Mori R, Nakashima M, Saitoh S, Yoshiura KI
Development (Cambridge, England) 2021 Aug 15;148(16)
Development (Cambridge, England) 2021 Aug 15;148(16)
HPV16 E6 enhances the radiosensitivity in HPV-positive human head and neck squamous cell carcinoma by regulating the miR-27a-3p/SMG1 axis.
Long D, Xu L, Deng Z, Guo D, Zhang Y, Liu Z, Zhang C
Infectious agents and cancer 2021 Aug 13;16(1):56
Infectious agents and cancer 2021 Aug 13;16(1):56
Targeted Ablation of Primary Cilia in Differentiated Dopaminergic Neurons Reduces Striatal Dopamine and Responsiveness to Metabolic Stress.
Mustafa R, Rawas C, Mannal N, Kreiner G, Spittau B, Kamińska K, Yilmaz R, Pötschke C, Kirsch J, Liss B, Tucker KL, Parlato R
Antioxidants (Basel, Switzerland) 2021 Aug 13;10(8)
Antioxidants (Basel, Switzerland) 2021 Aug 13;10(8)
Loss of Smad4 promotes aggressive lung cancer metastasis by de-repression of PAK3 via miRNA regulation.
Tan X, Tong L, Li L, Xu J, Xie S, Ji L, Fu J, Liu Q, Shen S, Liu Y, Xiao Y, Gao F, Moses RE, Bardeesy N, Wang Y, Zhang J, Tang L, Li L, Wong KK, Song D, Yang X, Liu J, Li X
Nature communications 2021 Aug 11;12(1):4853
Nature communications 2021 Aug 11;12(1):4853
Serum exosomal pregnancy zone protein as a promising biomarker in inflammatory bowel disease.
Shao J, Jin Y, Shao C, Fan H, Wang X, Yang G
Cellular & molecular biology letters 2021 Aug 10;26(1):36
Cellular & molecular biology letters 2021 Aug 10;26(1):36
Rab1A promotes cell proliferation and migration by upregulating Gli1 in colorectal cancer.
Peng C, Li X, Ye Z, Wu W
Scientific reports 2021 Aug 10;11(1):16243
Scientific reports 2021 Aug 10;11(1):16243
The Cell-Permeable Derivative of the Immunoregulatory Metabolite Itaconate, 4-Octyl Itaconate, Is Anti-Fibrotic in Systemic Sclerosis.
Henderson J, Dayalan Naidu S, Dinkova-Kostova AT, Przyborski S, Stratton R, O Reilly S
Cells 2021 Aug 10;10(8)
Cells 2021 Aug 10;10(8)
Humanin Alleviates Insulin Resistance in Polycystic Ovary Syndrome: A Human and Rat Model-Based Study.
Wang Y, Zeng Z, Zhao S, Tang L, Yan J, Li N, Zou L, Fan X, Xu C, Huang J, Xia W, Zhu C, Rao M
Endocrinology 2021 Aug 1;162(8)
Endocrinology 2021 Aug 1;162(8)
TSH Activates Macrophage Inflammation by G13- and G15-dependent Pathways.
Yang C, He Z, Zhang Q, Lu M, Zhao J, Chen W, Gao L
Endocrinology 2021 Aug 1;162(8)
Endocrinology 2021 Aug 1;162(8)
LncRNA ABCC6P1 promotes proliferation and migration of papillary thyroid cancer cells via Wnt/β-catenin signaling pathway.
Guan Y, Li Y, Yang QB, Yu J, Qiao H
Annals of translational medicine 2021 Apr;9(8):664
Annals of translational medicine 2021 Apr;9(8):664
ESM1 promotes triple-negative breast cancer cell proliferation through activating AKT/NF-κB/Cyclin D1 pathway.
Liu W, Yang Y, He B, Ma F, Sun F, Guo M, Zhang M, Dong Z
Annals of translational medicine 2021 Apr;9(7):533
Annals of translational medicine 2021 Apr;9(7):533
hucMSCs transplantation promotes locomotor function recovery, reduces apoptosis and inhibits demyelination after SCI in rats.
Liao Z, Yang X, Wang W, Deng W, Zhang Y, Song A, Ni B, Zhao H, Zhang S, Li Z
Neuropeptides 2021 Apr;86:102125
Neuropeptides 2021 Apr;86:102125
Ginsenoside-Rg1 acts as an IDO1 inhibitor, protects against liver fibrosis via alleviating IDO1-mediated the inhibition of DCs maturation.
Mo C, Xie S, Zeng T, Lai Y, Huang S, Zhou C, Yan W, Huang S, Gao L, Lv Z
Phytomedicine : international journal of phytotherapy and phytopharmacology 2021 Apr;84:153524
Phytomedicine : international journal of phytotherapy and phytopharmacology 2021 Apr;84:153524
Bergenin inhibits bladder cancer progression via activating the PPARγ/PTEN/Akt signal pathway.
Liu J, Zhang Y, Yu C, Zhang P, Gu S, Wang G, Xiao H, Li S
Drug development research 2021 Apr;82(2):278-286
Drug development research 2021 Apr;82(2):278-286
Arsenic-induced autophagy regulates apoptosis in AML-12 cells.
Yuan M, Sun Z, Manthari RK, Zhao Y, Guo Q, Yang K, Wang J
Toxicology in vitro : an international journal published in association with BIBRA 2021 Apr;72:105074
Toxicology in vitro : an international journal published in association with BIBRA 2021 Apr;72:105074
LncRNA XIST Promotes Migration and Invasion of Papillary Thyroid Cancer Cell by Modulating MiR-101-3p/CLDN1 Axis.
Du YL, Liang Y, Cao Y, Liu L, Li J, Shi GQ
Biochemical genetics 2021 Apr;59(2):437-452
Biochemical genetics 2021 Apr;59(2):437-452
Mutant IDH1 Enhances Temozolomide Sensitivity via Regulation of the ATM/CHK2 Pathway in Glioma.
Lin L, Cai J, Tan Z, Meng X, Li R, Li Y, Jiang C
Cancer research and treatment 2021 Apr;53(2):367-377
Cancer research and treatment 2021 Apr;53(2):367-377
Morusin inhibits the growth of human colorectal cancer HCT116‑derived sphere‑forming cells via the inactivation of Akt pathway.
Zhou Y, Li X, Ye M
International journal of molecular medicine 2021 Apr;47(4):1
International journal of molecular medicine 2021 Apr;47(4):1
Mono-macrophage-Derived MANF Protects Against Lipopolysaccharide-Induced Acute Kidney Injury via Inhibiting Inflammation and Renal M1 Macrophages.
Hou C, Mei Q, Song X, Bao Q, Li X, Wang D, Shen Y
Inflammation 2021 Apr;44(2):693-703
Inflammation 2021 Apr;44(2):693-703
Aspergillus fumigatus-Stimulated Human Corneal Epithelial Cells Induce Pyroptosis of THP-1 Macrophages by Secreting TSLP.
Ji Q, Wang L, Liu J, Wu Y, Lv H, Wen Y, Shi L, Qu B, Szentmáry N
Inflammation 2021 Apr;44(2):682-692
Inflammation 2021 Apr;44(2):682-692
Reduced intracellular chloride concentration impairs angiogenesis by inhibiting oxidative stress-mediated VEGFR2 activation.
Li K, Liu YY, Lv XF, Lin ZM, Zhang TT, Zhang FR, Guo JW, Hong Y, Liu X, Lin XC, Zhou JG, Wu QQ, Liang SJ, Shang JY
Acta pharmacologica Sinica 2021 Apr;42(4):560-572
Acta pharmacologica Sinica 2021 Apr;42(4):560-572
MiR-32-5p knockdown inhibits epithelial to mesenchymal transition and renal fibrosis by targeting SMAD7 in diabetic nephropathy.
Wang HJ, Liu H, Lin YH, Zhang SJ
Human & experimental toxicology 2021 Apr;40(4):587-595
Human & experimental toxicology 2021 Apr;40(4):587-595
Cartilage endplate stem cells inhibit intervertebral disc degeneration by releasing exosomes to nucleus pulposus cells to activate Akt/autophagy.
Luo L, Jian X, Sun H, Qin J, Wang Y, Zhang J, Shen Z, Yang D, Li C, Zhao P, Liu M, Tian Z, Zhou Y
Stem cells (Dayton, Ohio) 2021 Apr;39(4):467-481
Stem cells (Dayton, Ohio) 2021 Apr;39(4):467-481
LRP6 downregulation promotes cardiomyocyte proliferation and heart regeneration.
Wu Y, Zhou L, Liu H, Duan R, Zhou H, Zhang F, He X, Lu D, Xiong K, Xiong M, Zhuang J, Liu Y, Li L, Liang D, Chen YH
Cell research 2021 Apr;31(4):450-462
Cell research 2021 Apr;31(4):450-462
A chemical genetics approach to examine the functions of AAA proteins.
Cupido T, Jones NH, Grasso MJ, Pisa R, Kapoor TM
Nature structural & molecular biology 2021 Apr;28(4):388-397
Nature structural & molecular biology 2021 Apr;28(4):388-397
Programmed cell death 4 modulates lysosomal function by inhibiting TFEB translation.
Chen X, Guan Y, Zhang Y, Jia Y, Li W, Guo C, Li Y, Wang X, Shi Y, Wang Q, Zhu F, Li Y, Zhang L
Cell death and differentiation 2021 Apr;28(4):1237-1250
Cell death and differentiation 2021 Apr;28(4):1237-1250
Small molecule screening identified cepharanthine as an inhibitor of porcine reproductive and respiratory syndrome virus infection in vitro by suppressing integrins/ILK/RACK1/PKCα/NF-κB signalling axis.
Yang C, Zuo Q, Liu X, Zhao Q, Pu H, Gao L, Zhao L, Guo Z, Lin Y, Liu J, Bi J, Yin G
Veterinary microbiology 2021 Apr;255:109016
Veterinary microbiology 2021 Apr;255:109016
Characterization of an endoplasmic reticulum stress-related signature to evaluate immune features and predict prognosis in glioma.
Zhang Q, Guan G, Cheng P, Cheng W, Yang L, Wu A
Journal of cellular and molecular medicine 2021 Apr;25(8):3870-3884
Journal of cellular and molecular medicine 2021 Apr;25(8):3870-3884
ARID1B/SUB1-activated lncRNA HOXA-AS2 drives the malignant behaviour of hepatoblastoma through regulation of HOXA3.
Liu G, Liu B, Liu X, Xie L, He J, Zhang J, Dong R, Ma D, Dong K, Ye M
Journal of cellular and molecular medicine 2021 Apr;25(7):3524-3536
Journal of cellular and molecular medicine 2021 Apr;25(7):3524-3536
Helicobacter pylori inhibits autophagic flux and promotes its intracellular survival and colonization by down-regulating SIRT1.
Wang X, Wang B, Gao W, An Y, Dong G, Jia J, Yang Q
Journal of cellular and molecular medicine 2021 Apr;25(7):3348-3360
Journal of cellular and molecular medicine 2021 Apr;25(7):3348-3360
Glucagon-like peptide 2 attenuates intestinal mucosal barrier injury through the MLCK/pMLC signaling pathway in a piglet model.
Chang Y, Deng Q, Zhang Z, Zhao H, Tang J, Chen X, Liu G, Tian G, Cai J, Jia G
Journal of cellular physiology 2021 Apr;236(4):3015-3032
Journal of cellular physiology 2021 Apr;236(4):3015-3032
Ten-m/Odz3 regulates migration and differentiation of chondrogenic ATDC5 cells via RhoA-mediated actin reorganization.
Takano I, Takeshita N, Yoshida M, Seki D, Oyanagi T, Kimura S, Jiang W, Sasaki K, Sogi C, Kawatsu M, Takano-Yamamoto T
Journal of cellular physiology 2021 Apr;236(4):2906-2919
Journal of cellular physiology 2021 Apr;236(4):2906-2919
Involvement of oxidative stress-induced annulus fibrosus cell and nucleus pulposus cell ferroptosis in intervertebral disc degeneration pathogenesis.
Yang RZ, Xu WN, Zheng HL, Zheng XF, Li B, Jiang LS, Jiang SD
Journal of cellular physiology 2021 Apr;236(4):2725-2739
Journal of cellular physiology 2021 Apr;236(4):2725-2739
Novel role of CXCL14 in modulating STAR expression in luteinized granulosa cells: implication for progesterone synthesis in PCOS patients.
Qi J, Li J, Wang Y, Wang W, Zhu Q, He Y, Lu Y, Wu H, Li X, Zhu Z, Ding Y, Xu R, Sun Y
Translational research : the journal of laboratory and clinical medicine 2021 Apr;230:55-67
Translational research : the journal of laboratory and clinical medicine 2021 Apr;230:55-67
Melatonin exerts protective effects on diabetic retinopathy via inhibition of Wnt/β-catenin pathway as revealed by quantitative proteomics.
Yan M, Wang H, Gu Y, Li X, Tao L, Lu P
Experimental eye research 2021 Apr;205:108521
Experimental eye research 2021 Apr;205:108521
Depression-like behavior is associated with lower Per2 mRNA expression in the lateral habenula of rats.
Li Y, Li G, Li J, Cai X, Sun Y, Zhang B, Zhao H
Genes, brain, and behavior 2021 Apr;20(4):e12702
Genes, brain, and behavior 2021 Apr;20(4):e12702
MNK as a potential pharmacological target for suppressing LPS-induced acute lung injury in mice.
Gao J, Teng L, Yang S, Huang S, Li L, Zhou L, Liu G, Tang H
Biochemical pharmacology 2021 Apr;186:114499
Biochemical pharmacology 2021 Apr;186:114499
Harmine alleviates atherogenesis by inhibiting disturbed flow-mediated endothelial activation via protein tyrosine phosphatase PTPN14 and YAP.
Yang Y, Ma Q, Li Z, Wang H, Zhang C, Liu Y, Li B, Wang Y, Cui Q, Xue F, Ai D, Zhu Y, He J
British journal of pharmacology 2021 Apr;178(7):1524-1540
British journal of pharmacology 2021 Apr;178(7):1524-1540
A novel amphibian-derived peptide alleviated ultraviolet B-induced photodamage in mice.
Zhang X, Feng C, Wang S, Wang Y, Fu Z, Zhang Y, Sun H, Xie C, Fu Y, Tao J, Luo M, Yang X
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Apr;136:111258
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Apr;136:111258
Effects of miR-132-3p on progress and epithelial mesenchymal transition of non-small cell lung cancer via regulating KLF7.
Wang N, Xu Y, Guo Q, Zhu C, Zhao W, Qian W, Zheng M
Journal of thoracic disease 2021 Apr;13(4):2426-2436
Journal of thoracic disease 2021 Apr;13(4):2426-2436
POST1/C12ORF49 regulates the SREBP pathway by promoting site-1 protease maturation.
Xiao J, Xiong Y, Yang LT, Wang JQ, Zhou ZM, Dong LW, Shi XJ, Zhao X, Luo J, Song BL
Protein & cell 2021 Apr;12(4):279-296
Protein & cell 2021 Apr;12(4):279-296
Transcription factor EB promotes rheumatoid arthritis of Sprague-Dawley rats via regulating autophagy.
Xu L, Pan J
3 Biotech 2021 Apr;11(4):162
3 Biotech 2021 Apr;11(4):162
DBA/1 mice display equivalent cardiac function to C57BL/6J mice.
Wang Z, Zhou Z, Guo P, Wang M, Sun H, Tai Y, Xiao F, Han Y, Wei W, Wang Q
Experimental physiology 2021 Apr;106(4):868-881
Experimental physiology 2021 Apr;106(4):868-881
A partial loss-of-function variant in GNRNR gene in a Chinese cohort with idiopathic hypogonadotropic hypogonadism.
Chen Y, Sun T, Niu Y, Wang D, Liu K, Wang T, Wang S, Xu H, Liu J
Translational andrology and urology 2021 Apr;10(4):1676-1687
Translational andrology and urology 2021 Apr;10(4):1676-1687
PolyQ-expanded proteins impair cellular proteostasis of ataxin-3 through sequestering the co-chaperone HSJ1 into aggregates.
Yue HW, Hong JY, Zhang SX, Jiang LL, Hu HY
Scientific reports 2021 Apr 9;11(1):7815
Scientific reports 2021 Apr 9;11(1):7815
ATP6V0A1 encoding the a1-subunit of the V0 domain of vacuolar H(+)-ATPases is essential for brain development in humans and mice.
Aoto K, Kato M, Akita T, Nakashima M, Mutoh H, Akasaka N, Tohyama J, Nomura Y, Hoshino K, Ago Y, Tanaka R, Epstein O, Ben-Haim R, Heyman E, Miyazaki T, Belal H, Takabayashi S, Ohba C, Takata A, Mizuguchi T, Miyatake S, Miyake N, Fukuda A, Matsumoto N, Saitsu H
Nature communications 2021 Apr 8;12(1):2107
Nature communications 2021 Apr 8;12(1):2107
Therapeutic Effect of Endothelin-Converting Enzyme Inhibitor on Chronic Kidney Disease through the Inhibition of Endoplasmic Reticulum Stress and the NLRP3 Inflammasome.
Hsu YH, Zheng CM, Chou CL, Chen YJ, Lee YH, Lin YF, Chiu HW
Biomedicines 2021 Apr 7;9(4)
Biomedicines 2021 Apr 7;9(4)
Fangchinoline suppresses conjunctival melanoma by directly binding FUBP2 and inhibiting the homologous recombination pathway.
Bao K, Li Y, Wei J, Li R, Yang J, Shi J, Li B, Zhu J, Mao F, Jia R, Li J
Cell death & disease 2021 Apr 7;12(4):380
Cell death & disease 2021 Apr 7;12(4):380
DOCK7 protects against replication stress by promoting RPA stability on chromatin.
Gao M, Guo G, Huang J, Hou X, Ham H, Kim W, Zhao F, Tu X, Zhou Q, Zhang C, Zhu Q, Liu J, Yan Y, Xu Z, Yin P, Luo K, Weroha J, Deng M, Billadeau DD, Lou Z
Nucleic acids research 2021 Apr 6;49(6):3322-3337
Nucleic acids research 2021 Apr 6;49(6):3322-3337
MCPIP1-mediated NFIC alternative splicing inhibits proliferation of triple-negative breast cancer via cyclin D1-Rb-E2F1 axis.
Chen F, Wang Q, Yu X, Yang N, Wang Y, Zeng Y, Zheng Z, Zhou F, Zhou Y
Cell death & disease 2021 Apr 6;12(4):370
Cell death & disease 2021 Apr 6;12(4):370
Regulation of MRP4 Expression by circHIPK3 via Sponging miR-124-3p/miR-4524-5p in Hepatocellular Carcinoma.
Hu H, Wang Y, Qin Z, Sun W, Chen Y, Wang J, Wang Y, Nie J, Chen L, Cai S, Yu L, Zeng S
Biomedicines 2021 Apr 30;9(5)
Biomedicines 2021 Apr 30;9(5)
ARID3A promotes the development of colorectal cancer by upregulating AURKA.
Tang J, Yang L, Li Y, Ning X, Chaulagain A, Wang T, Wang D
Carcinogenesis 2021 Apr 30;42(4):578-586
Carcinogenesis 2021 Apr 30;42(4):578-586
Anti-tumor activity of a novel proteasome inhibitor D395 against multiple myeloma and its lower cardiotoxicity compared with carfilzomib.
Shen X, Wu C, Lei M, Yan Q, Zhang H, Zhang L, Wang X, Yang Y, Li J, Zhu Y, Chen L
Cell death & disease 2021 Apr 30;12(5):429
Cell death & disease 2021 Apr 30;12(5):429
The role of E26 transformation-specific variant transcription factor 5 in colorectal cancer cell proliferation and cell cycle progression.
Peng Y, Feng H, Wang C, Song Z, Zhang Y, Liu K, Cheng X, Zhao R
Cell death & disease 2021 Apr 30;12(5):427
Cell death & disease 2021 Apr 30;12(5):427
Tumor-derived exosomal circPSMA1 facilitates the tumorigenesis, metastasis, and migration in triple-negative breast cancer (TNBC) through miR-637/Akt1/β-catenin (cyclin D1) axis.
Yang SJ, Wang DD, Zhong SL, Chen WQ, Wang FL, Zhang J, Xu WX, Xu D, Zhang Q, Li J, Zhang HD, Hou JC, Mao L, Tang JH
Cell death & disease 2021 Apr 28;12(5):420
Cell death & disease 2021 Apr 28;12(5):420
Multi-omics analysis to identify susceptibility genes for colorectal cancer.
Yuan Y, Bao J, Chen Z, Villanueva AD, Wen W, Wang F, Zhao D, Fu X, Cai Q, Long J, Shu XO, Zheng D, Moreno V, Zheng W, Lin W, Guo X
Human molecular genetics 2021 Apr 27;30(5):321-330
Human molecular genetics 2021 Apr 27;30(5):321-330
Interaction of NEP with G Protein Pathway Suppressor 2 Facilitates Influenza A Virus Replication by Weakening the Inhibition of GPS2 to RNA Synthesis and Ribonucleoprotein Assembly.
Gong W, He X, Huang K, Zhang Y, Li C, Yang Y, Zou Z, Jin M
Journal of virology 2021 Apr 26;95(10)
Journal of virology 2021 Apr 26;95(10)
Knockdown of the Ribosomal Protein eL38 in HEK293 Cells Changes the Translational Efficiency of Specific Genes.
Gopanenko AV, Kolobova AV, Tupikin AE, Kabilov MR, Malygin AA, Karpova GG
International journal of molecular sciences 2021 Apr 26;22(9)
International journal of molecular sciences 2021 Apr 26;22(9)
ZIP8 mediates the extracellular matrix degradation of nucleus pulposus cells via NF-κB signaling pathway.
Ding W, Ge Y, Sun H, Xu J, Gu H, Bian C, Chen H, Jiang L, Yin X
Biochemical and biophysical research communications 2021 Apr 23;550:30-36
Biochemical and biophysical research communications 2021 Apr 23;550:30-36
Abelson interactor 1 splice isoform-L plays an anti-oncogenic role in colorectal carcinoma through interactions with WAVE2 and full-length Abelson interactor 1.
Li K, Peng YF, Guo JZ, Li M, Zhang Y, Chen JY, Lin TR, Yu X, Yu WD
World journal of gastroenterology 2021 Apr 21;27(15):1595-1615
World journal of gastroenterology 2021 Apr 21;27(15):1595-1615
Impaired 26S Proteasome Assembly Precedes Neuronal Loss in Mutant UBQLN2 Rats.
Zhang W, Huang B, Gao L, Huang C
International journal of molecular sciences 2021 Apr 21;22(9)
International journal of molecular sciences 2021 Apr 21;22(9)
Generation of a Polyclonal Antibody against the Mouse Metal Transporter ZIP8.
Wei G, Wu Y, Zhao N
Antibodies (Basel, Switzerland) 2021 Apr 21;10(2)
Antibodies (Basel, Switzerland) 2021 Apr 21;10(2)
Inhibition of Notch1 signaling reduces hepatocyte injury in nonalcoholic fatty liver disease via autophagy.
Zhang M, Wu P, Li M, Guo Y, Tian T, Liao X, Tan S
Biochemical and biophysical research communications 2021 Apr 2;547:131-138
Biochemical and biophysical research communications 2021 Apr 2;547:131-138
Role of Small Envelope Protein in Sustaining the Intracellular and Extracellular Levels of Hepatitis B Virus Large and Middle Envelope Proteins.
Zhang J, Wang Y, Fu S, Yuan Q, Wang Q, Xia N, Wen Y, Li J, Tong S
Viruses 2021 Apr 2;13(4)
Viruses 2021 Apr 2;13(4)
CircLIFR synergizes with MSH2 to attenuate chemoresistance via MutSα/ATM-p73 axis in bladder cancer.
Zhang H, Xiao X, Wei W, Huang C, Wang M, Wang L, He Y, Sun J, Jiang Y, Jiang G, Zhang X
Molecular cancer 2021 Apr 19;20(1):70
Molecular cancer 2021 Apr 19;20(1):70
RUNX1 promotes MAPK signaling to increase tumor progression and metastasis via OPN in head and neck cancer.
Liu K, Hu H, Jiang H, Zhang H, Gong S, Wei D, Yu Z
Carcinogenesis 2021 Apr 17;42(3):414-422
Carcinogenesis 2021 Apr 17;42(3):414-422
miR-324-3p reverses cisplatin resistance by inducing GPX4-mediated ferroptosis in lung adenocarcinoma cell line A549.
Deng SH, Wu DM, Li L, Liu T, Zhang T, Li J, Yu Y, He M, Zhao YY, Han R, Xu Y
Biochemical and biophysical research communications 2021 Apr 16;549:54-60
Biochemical and biophysical research communications 2021 Apr 16;549:54-60
Crystal structures reveal a novel dimer of the RWD domain of human general control nonderepressible 2.
Hei Z, Wu S, Zheng L, Zhou J, Liu Z, Wang J, Fang P
Biochemical and biophysical research communications 2021 Apr 16;549:164-170
Biochemical and biophysical research communications 2021 Apr 16;549:164-170
Promyelocytic leukemia protein promotes the phenotypic switch of smooth muscle cells in atherosclerotic plaques of human coronary arteries.
Karle W, Becker S, Stenzel P, Knosalla C, Siegel G, Baum O, Zakrzewicz A, Berkholz J
Clinical science (London, England : 1979) 2021 Apr 16;135(7):887-905
Clinical science (London, England : 1979) 2021 Apr 16;135(7):887-905
Effects of CMYA1 overexpression on cardiac structure and function in mice.
Li C, Zhang H, Xie Y, Liu S, Zhao R, Huang J, Huang J, Wei Y
Acta biochimica et biophysica Sinica 2021 Apr 15;53(5):593-600
Acta biochimica et biophysica Sinica 2021 Apr 15;53(5):593-600
Dual effects of fibrinogen decoration on the tuning of silica nanoparticles-induced autophagic response: The implication of sedimentation and internalization.
Zhang L, Wei W, Liu Z, Liu X, Song E, Song Y
Journal of hazardous materials 2021 Apr 15;408:124467
Journal of hazardous materials 2021 Apr 15;408:124467
Chemoproteomics-enabled discovery of covalent RNF114-based degraders that mimic natural product function.
Luo M, Spradlin JN, Boike L, Tong B, Brittain SM, McKenna JM, Tallarico JA, Schirle M, Maimone TJ, Nomura DK
Cell chemical biology 2021 Apr 15;28(4):559-566.e15
Cell chemical biology 2021 Apr 15;28(4):559-566.e15
Glaucocalyxin A induces cell cycle arrest and apoptosis via inhibiting NF-κB/p65 signaling pathway in melanoma cells.
Chen J, Zhang W, Pan C, Fan J, Zhong X, Tang S
Life sciences 2021 Apr 15;271:119185
Life sciences 2021 Apr 15;271:119185
Synthesis, characterization, and targeted chemotherapy of SCT200-linker-monomethyl auristatin E conjugates.
Hu X, Jiang H, Bai W, Liu X, Miao Q, Wang L, Jin J, Cui A, Liu R, Li Z
European journal of medicinal chemistry 2021 Apr 15;216:113297
European journal of medicinal chemistry 2021 Apr 15;216:113297
The biological function and clinical significance of STIL in osteosarcoma.
Ji SF, Wen SL, Sun Y, Huang PW, Wu H, He ML
Cancer cell international 2021 Apr 15;21(1):218
Cancer cell international 2021 Apr 15;21(1):218
Loss of Mitochondrial Protease CLPP Activates Type I IFN Responses through the Mitochondrial DNA-cGAS-STING Signaling Axis.
Torres-Odio S, Lei Y, Gispert S, Maletzko A, Key J, Menissy SS, Wittig I, Auburger G, West AP
Journal of immunology (Baltimore, Md. : 1950) 2021 Apr 15;206(8):1890-1900
Journal of immunology (Baltimore, Md. : 1950) 2021 Apr 15;206(8):1890-1900
AKR1B10 negatively regulates autophagy through reducing GAPDH upon glucose starvation in colon cancer.
Li W, Liu C, Huang Z, Shi L, Zhong C, Zhou W, Meng P, Li Z, Wang S, Luo F, Yan J, Wu T
Journal of cell science 2021 Apr 15;134(8)
Journal of cell science 2021 Apr 15;134(8)
KLF7/VPS35 axis contributes to hepatocellular carcinoma progression through CCDC85C-activated β-catenin pathway.
Guo Y, Chai B, Jia J, Yang M, Li Y, Zhang R, Wang S, Xu J
Cell & bioscience 2021 Apr 15;11(1):73
Cell & bioscience 2021 Apr 15;11(1):73
Cytoplasmic DNA sensing by KU complex in aged CD4(+) T cell potentiates T cell activation and aging-related autoimmune inflammation.
Wang Y, Fu Z, Li X, Liang Y, Pei S, Hao S, Zhu Q, Yu T, Pei Y, Yuan J, Ye J, Fu J, Xu J, Hong J, Yang R, Hou H, Huang X, Peng C, Zheng M, Xiao Y
Immunity 2021 Apr 13;54(4):632-647.e9
Immunity 2021 Apr 13;54(4):632-647.e9
TDP-43 prevents endogenous RNAs from triggering a lethal RIG-I-dependent interferon response.
Dunker W, Ye X, Zhao Y, Liu L, Richardson A, Karijolich J
Cell reports 2021 Apr 13;35(2):108976
Cell reports 2021 Apr 13;35(2):108976
Changes in hepatic triglyceride content with the activation of ER stress and increased FGF21 secretion during pregnancy.
Lu J, Gong Y, Wei X, Yao Z, Yang R, Xin J, Gao L, Shao S
Nutrition & metabolism 2021 Apr 13;18(1):40
Nutrition & metabolism 2021 Apr 13;18(1):40
EpCAM promotes endosomal modulation of the cortical RhoA zone for epithelial organization.
Gaston C, De Beco S, Doss B, Pan M, Gauquelin E, D'Alessandro J, Lim CT, Ladoux B, Delacour D
Nature communications 2021 Apr 13;12(1):2226
Nature communications 2021 Apr 13;12(1):2226
TRIM39 deficiency inhibits tumor progression and autophagic flux in colorectal cancer via suppressing the activity of Rab7.
Hu J, Ding X, Tian S, Chu Y, Liu Z, Li Y, Li X, Wang G, Wang L, Wang Z
Cell death & disease 2021 Apr 12;12(4):391
Cell death & disease 2021 Apr 12;12(4):391
Reciprocal regulation of RIG-I and XRCC4 connects DNA repair with RIG-I immune signaling.
Guo G, Gao M, Gao X, Zhu B, Huang J, Tu X, Kim W, Zhao F, Zhou Q, Zhu S, Wu Z, Yan Y, Zhang Y, Zeng X, Zhu Q, Yin P, Luo K, Sun J, Deng M, Lou Z
Nature communications 2021 Apr 12;12(1):2187
Nature communications 2021 Apr 12;12(1):2187
ADAMTS19 Suppresses Cell Migration and Invasion by Targeting S100A16 via the NF-κB Pathway in Human Gastric Cancer.
Jiang Y, Yu X, Zhao Y, Huang J, Li T, Chen H, Zhou J, Huang Z, Yang Z
Biomolecules 2021 Apr 12;11(4)
Biomolecules 2021 Apr 12;11(4)
NET1 promotes HCC growth and metastasis in vitro and in vivo via activating the Akt signaling pathway.
Chen ZH, Ni QZ, Zhang XP, Ma N, Feng JK, Wang K, Li JJ, Xie D, Ma XY, Cheng SQ
Aging 2021 Apr 11;13(7):10672-10687
Aging 2021 Apr 11;13(7):10672-10687
p53-targeted lncRNA ST7-AS1 acts as a tumour suppressor by interacting with PTBP1 to suppress the Wnt/β-catenin signalling pathway in glioma.
Sheng J, He X, Yu W, Chen Y, Long Y, Wang K, Zhu S, Liu Q
Cancer letters 2021 Apr 10;503:54-68
Cancer letters 2021 Apr 10;503:54-68
Dcaf11 activates Zscan4-mediated alternative telomere lengthening in early embryos and embryonic stem cells.
Le R, Huang Y, Zhang Y, Wang H, Lin J, Dong Y, Li Z, Guo M, Kou X, Zhao Y, Chen M, Zhu Q, Zhao A, Yin J, Sun J, Su Z, Shi K, Gao Y, Chen J, Liu W, Kang L, Wang Y, Li C, Liu X, Gao R, Wang H, Ju Z, Gao S
Cell stem cell 2021 Apr 1;28(4):732-747.e9
Cell stem cell 2021 Apr 1;28(4):732-747.e9
Polychlorinated biphenyl quinone regulates MLKL phosphorylation that stimulates exosome biogenesis and secretion via a short negative feedback loop.
Peng L, Wang Y, Yang B, Qin Q, Song E, Song Y
Environmental pollution (Barking, Essex : 1987) 2021 Apr 1;274:115606
Environmental pollution (Barking, Essex : 1987) 2021 Apr 1;274:115606
Design and screening of a novel neuropilin-1 targeted penetrating peptide for anti-angiogenic therapy in glioma.
Zhao L, Chen H, Lu L, Zhao C, Malichewe CV, Wang L, Guo X, Zhang X
Life sciences 2021 Apr 1;270:119113
Life sciences 2021 Apr 1;270:119113
RETRACTED: MicroRNA-376b-5p targets SOX7 to alleviate ischemic brain injury in a mouse model through activating Wnt/β-catenin signaling pathway.
Zhao B, Wang P, Yu J, Zhang Y
Life sciences 2021 Apr 1;270:119072
Life sciences 2021 Apr 1;270:119072
RANK promotes colorectal cancer migration and invasion by activating the Ca(2+)-calcineurin/NFATC1-ACP5 axis.
Liang Q, Wang Y, Lu Y, Zhu Q, Xie W, Tang N, Huang L, An T, Zhang D, Yan A, Liu S, Ye L, Zhu C
Cell death & disease 2021 Apr 1;12(4):336
Cell death & disease 2021 Apr 1;12(4):336
Identification of Beilschmiedia tsangii Root Extract as a Liver Cancer Cell-Normal Keratinocyte Dual-Selective NRF2 Regulator.
Chen YS, Chang HS, Hsiao HH, Chen YF, Kuo YP, Yen FL, Yen CH
Antioxidants (Basel, Switzerland) 2021 Apr 1;10(4)
Antioxidants (Basel, Switzerland) 2021 Apr 1;10(4)
Lycopene alleviates oxidative stress via the PI3K/Akt/Nrf2pathway in a cell model of Alzheimer's disease.
Fang Y, Ou S, Wu T, Zhou L, Tang H, Jiang M, Xu J, Guo K
PeerJ 2020;8:e9308
PeerJ 2020;8:e9308
Conditioned medium from M2b macrophages modulates the proliferation, migration, and apoptosis of pulmonary artery smooth muscle cells by deregulating the PI3K/Akt/FoxO3a pathway.
Huang S, Yue Y, Feng K, Huang X, Li H, Hou J, Yang S, Huang S, Liang M, Chen G, Wu Z
PeerJ 2020;8:e9110
PeerJ 2020;8:e9110
Icariin protects against sodium azide-induced neurotoxicity by activating the PI3K/Akt/GSK-3β signaling pathway.
Zhang Y, Huang N, Lu H, Huang J, Jin H, Shi J, Jin F
PeerJ 2020;8:e8955
PeerJ 2020;8:e8955
Glycyrrhizin suppresses epithelial-mesenchymal transition by inhibiting high-mobility group box1 via the TGF-β1/Smad2/3 pathway in lung epithelial cells.
Gui Y, Sun J, You W, Wei Y, Tian H, Jiang S
PeerJ 2020;8:e8514
PeerJ 2020;8:e8514
miR-29a-3p directly targets Smad nuclear interacting protein 1 and inhibits the migration and proliferation of cervical cancer HeLa cells.
Chen Y, Zhang W, Yan L, Zheng P, Li J
PeerJ 2020;8:e10148
PeerJ 2020;8:e10148
Examination of the Effect of a 50-Hz Electromagnetic Field at 500 μT on Parameters Related With the Cardiovascular System in Rats.
Zhang Y, Li L, Liu X, Ding L, Wu X, Wang J, He M, Hou H, Ruan G, Lai J, Chen C
Frontiers in public health 2020;8:87
Frontiers in public health 2020;8:87
Mimicking the Organic and Inorganic Composition of Anabolic Bone Enhances Human Mesenchymal Stem Cell Osteoinduction and Scaffold Mechanical Properties.
Mondragón E, Cowdin M, Taraballi F, Minardi S, Tasciotti E, Gregory CA, Kaunas R
Frontiers in bioengineering and biotechnology 2020;8:753
Frontiers in bioengineering and biotechnology 2020;8:753
Histone Deacetylases Inhibit the Snail2-Mediated EMT During Metastasis of Hepatocellular Carcinoma Cells.
Hu Y, Nie Q, Dai M, Chen F, Wu H
Frontiers in cell and developmental biology 2020;8:752
Frontiers in cell and developmental biology 2020;8:752
RNA-Binding Protein HuR Suppresses Inflammation and Promotes Extracellular Matrix Homeostasis via NKRF in Intervertebral Disc Degeneration.
Shao Z, Tu Z, Shi Y, Li S, Wu A, Wu Y, Tian N, Sun L, Pan Z, Chen L, Gao W, Zhou Y, Wang X, Zhang X
Frontiers in cell and developmental biology 2020;8:611234
Frontiers in cell and developmental biology 2020;8:611234
Knockdown of POSTN Inhibits Osteogenic Differentiation of Mesenchymal Stem Cells From Patients With Steroid-Induced Osteonecrosis.
Han L, Gong S, Wang R, Liu S, Wang B, Chen G, Gong T, Xu W
Frontiers in cell and developmental biology 2020;8:606289
Frontiers in cell and developmental biology 2020;8:606289
Caspase-8 Inhibition Prevents the Cleavage and Degradation of E3 Ligase Substrate Receptor Cereblon and Potentiates Its Biological Function.
Zhou L, Yu W, Jayabalan DS, Niesvizky R, Jaffrey SR, Huang X, Xu G
Frontiers in cell and developmental biology 2020;8:605989
Frontiers in cell and developmental biology 2020;8:605989
HDAC6 Regulates the Fusion of Autophagosome and Lysosome to Involve in Odontoblast Differentiation.
Zhan Y, Wang H, Zhang L, Pei F, Chen Z
Frontiers in cell and developmental biology 2020;8:605609
Frontiers in cell and developmental biology 2020;8:605609
Transient Receptor Potential Channel 6 Knockout Ameliorates Kidney Fibrosis by Inhibition of Epithelial-Mesenchymal Transition.
Zhang Y, Yin N, Sun A, Wu Q, Hu W, Hou X, Zeng X, Zhu M, Liao Y
Frontiers in cell and developmental biology 2020;8:602703
Frontiers in cell and developmental biology 2020;8:602703
Iron Overload Is Associated With Accelerated Progression of Osteoarthritis: The Role of DMT1 Mediated Iron Homeostasis.
Jing X, Lin J, Du T, Jiang Z, Li T, Wang G, Liu X, Cui X, Sun K
Frontiers in cell and developmental biology 2020;8:594509
Frontiers in cell and developmental biology 2020;8:594509
miR-766-3p Targeting BCL9L Suppressed Tumorigenesis, Epithelial-Mesenchymal Transition, and Metastasis Through the β-Catenin Signaling Pathway in Osteosarcoma Cells.
Zhang S, Chen H, Liu W, Fang L, Qian Z, Kong R, Zhang Q, Li J, Cao X
Frontiers in cell and developmental biology 2020;8:594135
Frontiers in cell and developmental biology 2020;8:594135
Deficiency of LMP10 Attenuates Diet-Induced Atherosclerosis by Inhibiting Macrophage Polarization and Inflammation in Apolipoprotein E Deficient Mice.
Liao J, An X, Yang X, Lin QY, Liu S, Xie Y, Bai J, Xia YL, Li HH
Frontiers in cell and developmental biology 2020;8:592048
Frontiers in cell and developmental biology 2020;8:592048
p.His16Arg of STXBP1 (MUNC18-1) Associated With Syntaxin 3B Causes Autosomal Dominant Congenital Nystagmus.
Li Y, Jiang L, Wang L, Wang C, Liu C, Guo A, Liu M, Zhang L, Ma C, Zhang X, Gao S, Liu JY
Frontiers in cell and developmental biology 2020;8:591781
Frontiers in cell and developmental biology 2020;8:591781
EZH2-Inhibited MicroRNA-454-3p Promotes M2 Macrophage Polarization in Glioma.
Qi B, Yang C, Zhu Z, Chen H
Frontiers in cell and developmental biology 2020;8:574940
Frontiers in cell and developmental biology 2020;8:574940
Modulation of Increased mGluR1 Signaling by RGS8 Protects Purkinje Cells From Dendritic Reduction and Could Be a Common Mechanism in Diverse Forms of Spinocerebellar Ataxia.
Wu QW, Kapfhammer JP
Frontiers in cell and developmental biology 2020;8:569889
Frontiers in cell and developmental biology 2020;8:569889
MicroRNA-221/222 Mediates ADSC-Exosome-Induced Cardioprotection Against Ischemia/Reperfusion by Targeting PUMA and ETS-1.
Lai TC, Lee TL, Chang YC, Chen YC, Lin SR, Lin SW, Pu CM, Tsai JS, Chen YL
Frontiers in cell and developmental biology 2020;8:569150
Frontiers in cell and developmental biology 2020;8:569150
Glycogen Phosphorylase B Is Regulated by miR101-3p and Promotes Hepatocellular Carcinoma Tumorigenesis.
Cui G, Wang H, Liu W, Xing J, Song W, Zeng Z, Liu L, Wang H, Wang X, Luo H, Leng X, Shen S
Frontiers in cell and developmental biology 2020;8:566494
Frontiers in cell and developmental biology 2020;8:566494
Oct4 Regulates the Transition of Cancer Stem-Like Cells to Tumor Endothelial-Like Cells in Human Liver Cancer.
Liu HL, Tang HT, Yang HL, Deng TT, Xu YP, Xu SQ, Peng L, Wang Z, Fang Q, Kuang XY, Li QS
Frontiers in cell and developmental biology 2020;8:563316
Frontiers in cell and developmental biology 2020;8:563316
Overexpression of FAM46A, a Non-canonical Poly(A) Polymerase, Promotes Hemin-Induced Hemoglobinization in K562 Cells.
Lin HH, Lo YL, Wang WC, Huang KY, I KY, Chang GW
Frontiers in cell and developmental biology 2020;8:414
Frontiers in cell and developmental biology 2020;8:414
Siwei Jianbu decoction improves painful paclitaxel-induced peripheral neuropathy in mouse model by modulating the NF-κB and MAPK signaling pathways.
Suo J, Wang M, Zhang P, Lu Y, Xu R, Zhang L, Qiu S, Zhang Q, Qian Y, Meng J, Zhu J
Regenerative medicine research 2020;8:2
Regenerative medicine research 2020;8:2
The Changes of Twist1 Pathway in Pulmonary Microvascular Permeability in a Newborn Rat Model of Hyperoxia-Induced Acute Lung Injury.
Ruan Y, Dong W, Kang L, Lei X, Zhang R, Wang F, Zhu X
Frontiers in pediatrics 2020;8:190
Frontiers in pediatrics 2020;8:190
CDKN2a/p16 Antagonizes Hepatic Stellate Cell Activation and Liver Fibrosis by Modulating ROS Levels.
Lv F, Li N, Kong M, Wu J, Fan Z, Miao D, Xu Y, Ye Q, Wang Y
Frontiers in cell and developmental biology 2020;8:176
Frontiers in cell and developmental biology 2020;8:176
Crx Is Posttranscriptionally Regulated by Light Stimulation in Postnatal Rat Retina.
Wu Y, Qiu J, Chen S, Chen X, Zhang J, Zhuang J, Liu S, Yang M, Zhou P, Chen H, Ge J, Yu K, Zhuang J
Frontiers in cell and developmental biology 2020;8:174
Frontiers in cell and developmental biology 2020;8:174
S-Adenosylmethionine Alleviates Amyloid-β-Induced Neural Injury by Enhancing Trans-Sulfuration Pathway Activity in Astrocytes.
Wan X, Ma B, Wang X, Guo C, Sun J, Cui J, Li L
Journal of Alzheimer's disease : JAD 2020;76(3):981-995
Journal of Alzheimer's disease : JAD 2020;76(3):981-995
Dendrobium nobile Lindl. Alkaloids Ameliorate Cognitive Dysfunction in Senescence Accelerated SAMP8 Mice by Decreasing Amyloid-β Aggregation and Enhancing Autophagy Activity.
Lv LL, Liu B, Liu J, Li LS, Jin F, Xu YY, Wu Q, Liu J, Shi JS
Journal of Alzheimer's disease : JAD 2020;76(2):657-669
Journal of Alzheimer's disease : JAD 2020;76(2):657-669
Oxytocin Alleviates MPTP-Induced Neurotoxicity in Mice by Targeting MicroRNA-26a/Death-Associated Protein Kinase 1 Pathway.
Almansoub HAMM, Tang H, Wu Y, Wang DQ, Mahaman YAR, Salissou MTM, Lu Y, Hu F, Zhou LT, Almansob YAM, Liu D
Journal of Alzheimer's disease : JAD 2020;74(3):883-901
Journal of Alzheimer's disease : JAD 2020;74(3):883-901
miR-193a-3p Mediates Placenta Accreta Spectrum Development by Targeting EFNB2 via Epithelial-Mesenchymal Transition Pathway Under Decidua Defect Conditions.
Li N, Hou R, Yang T, Liu C, Wei J
Frontiers in molecular biosciences 2020;7:613802
Frontiers in molecular biosciences 2020;7:613802
DGCR8/miR-106 Axis Enhances Radiosensitivity of Head and Neck Squamous Cell Carcinomas by Downregulating RUNX3.
Zhang C, Chen H, Deng Z, Long D, Xu L, Liu Z
Frontiers in medicine 2020;7:582097
Frontiers in medicine 2020;7:582097
Identification of Transcriptional Variation in Aortic Remodeling Using a Murine Transverse Aortic Constriction (TAC) Model.
Zhang X, Feng T, Zeng XI, Liang H, Situ B, Zhang Q, Zhou F, Chen Y, Wang T, Cai D, Lin X, Xiu J, Zheng L
Frontiers in cardiovascular medicine 2020;7:581362
Frontiers in cardiovascular medicine 2020;7:581362
Dioscin Protects against Aβ1-42 Oligomers-Induced Neurotoxicity via the Function of SIRT3 and Autophagy.
Zhang Z, Han K, Wang C, Sun C, Jia N
Chemical & pharmaceutical bulletin 2020;68(8):717-725
Chemical & pharmaceutical bulletin 2020;68(8):717-725
Osthole: A Traditional Chinese Medicine for Ocular Anti-Angiogenic Therapy.
Zhang QY, Tao SY, Lu C, Li JJ, Li XM, Jiang Q, Yan B
Ophthalmic research 2020;63(5):483-490
Ophthalmic research 2020;63(5):483-490
Electroacupuncture Improves Motor Symptoms of Parkinson's Disease and Promotes Neuronal Autophagy Activity in Mouse Brain.
Hsu WT, Chen YH, Yang HB, Lin JG, Hung SY
The American journal of Chinese medicine 2020;48(7):1651-1669
The American journal of Chinese medicine 2020;48(7):1651-1669
Overexpression of MECP2 attenuates cigarette smoke extracts induced lung epithelial cell injury by promoting CYP1B1 methylation.
Lin J, Peng J, Liu G, Deng L
The Journal of toxicological sciences 2020;45(3):177-186
The Journal of toxicological sciences 2020;45(3):177-186
TRIB3 promotes hepatocellular carcinoma growth and predicts poor prognosis.
Wang XJ, Li FF, Zhang YJ, Jiang M, Ren WH
Cancer biomarkers : section A of Disease markers 2020;29(3):307-315
Cancer biomarkers : section A of Disease markers 2020;29(3):307-315
BMSC-derived leptin and IGFBP2 promote erlotinib resistance in lung adenocarcinoma cells through IGF-1R activation in hypoxic environment.
Wang F, Zhang L, Sai B, Wang L, Zhang X, Zheng L, Tang J, Li G, Xiang J
Cancer biology & therapy 2020;21(1):61-71
Cancer biology & therapy 2020;21(1):61-71
DLX6-AS1 promotes cell proliferation, migration and EMT of gastric cancer through FUS-regulated MAP4K1.
Wu Q, Ma J, Meng W, Hui P
Cancer biology & therapy 2020;21(1):17-25
Cancer biology & therapy 2020;21(1):17-25
Effect of Wenshen-Yanggan Decoction on Movement Disorder and Substantia Nigra Dopaminergic Neurons in Mice with Chronic Parkinson's Disease.
Tang L, Chen C, Xia B, Wu W, Wei R, Zhu G, Tang J, Zhou X, Liang Y, Zhang ZN, Lu Y, Yang Y, Zhao Y
Evidence-based complementary and alternative medicine : eCAM 2020;2020:9838295
Evidence-based complementary and alternative medicine : eCAM 2020;2020:9838295
Adrenal (Pro)renin Receptor Expression and Serum Soluble (Pro)renin Receptor Concentration in Primary Aldosteronism.
Watanabe D, Morimoto S, Morishima N, Kato Y, Nagashima Y, Shibata N, Ichihara A
International journal of endocrinology 2020;2020:9640103
International journal of endocrinology 2020;2020:9640103
Autophagy Contributes to Host Immunity and Protection against Zika Virus Infection via Type I IFN Signaling.
Huang Y, Wang Y, Meng S, Chen Z, Kong H, Pan T, Lu G, Li X
Mediators of inflammation 2020;2020:9527147
Mediators of inflammation 2020;2020:9527147
Distinct Expression Patterns of Apoptosis and Autophagy-Associated Proteins and Genes during Postnatal Development of Spiral Ganglion Neurons in Rat.
Hou S, Chen P, Chen J, Chen J, Sun L, Chen J, He B, Li Y, Qin H, Hong Y, Li S, He J, Gao D, Mammano F, Yang J
Neural plasticity 2020;2020:9387560
Neural plasticity 2020;2020:9387560
Citron Rho-Interacting Serine/Threonine Kinase Promotes HIF1a-CypA Signaling and Growth of Human Pancreatic Adenocarcinoma.
Cong L, Bai Z, Du Y, Cheng Y
BioMed research international 2020;2020:9210891
BioMed research international 2020;2020:9210891
Electroacupuncture Improved Chronic Cerebral Hypoperfusion-Induced Anxiety-Like Behavior and Memory Impairments in Spontaneously Hypertensive Rats by Downregulating the ACE/Ang II/AT1R Axis and Upregulating the ACE2/Ang-(1-7)/MasR Axis.
Feng P, Wu Z, Liu H, Shen Y, Yao X, Li X, Shen Z
Neural plasticity 2020;2020:9076042
Neural plasticity 2020;2020:9076042
PBX3 Promotes Tumor Growth and Angiogenesis via Activation of AT1R/VEGFR2 Pathway in Papillary Thyroid Carcinoma.
Chen Q, Yu WY, Zhang HH, Zhang SZ, Fang J, Wu F, Ying HZ, Yu CH
BioMed research international 2020;2020:8954513
BioMed research international 2020;2020:8954513
AURKA Increase the Chemosensitivity of Colon Cancer Cells to Oxaliplatin by Inhibiting the TP53-Mediated DNA Damage Response Genes.
Shan B, Zhao R, Zhou J, Zhang M, Qi X, Wang T, Gong J, Wu Y, Zhu Y, Yang W, Zhang Y, Wang G, Li X
BioMed research international 2020;2020:8916729
BioMed research international 2020;2020:8916729
Jian-Pi-Yi-Shen Regulates EPO and Iron Recycling Protein Expressions in Anemic Rats with Chronic Kidney Disease: Accumulation of Hypoxia Inducible Factor-2α via ERK Signaling.
Wang F, Yu H, Huang S, Zheng L, Zheng P, Zhang S, Li S, Chen J
Evidence-based complementary and alternative medicine : eCAM 2020;2020:8894257
Evidence-based complementary and alternative medicine : eCAM 2020;2020:8894257
Exosomes from Bone Marrow Microenvironment-Derived Mesenchymal Stem Cells Affect CML Cells Growth and Promote Drug Resistance to Tyrosine Kinase Inhibitors.
Zhang X, Yang Y, Yang Y, Chen H, Tu H, Li J
Stem cells international 2020;2020:8890201
Stem cells international 2020;2020:8890201
Responsive Expression of MafF to β-Amyloid-Induced Oxidative Stress.
Wang X, Zhang Y, Wan X, Guo C, Cui J, Sun J, Li L
Disease markers 2020;2020:8861358
Disease markers 2020;2020:8861358
EA Ameliorated Depressive Behaviors in CUMS Rats and Was Related to Its Suppressing Autophagy in the Hippocampus.
Zhang Z, Cai X, Yao Z, Wen F, Fu Z, Zhang J, Zhong Z, Huang Y, Qu S
Neural plasticity 2020;2020:8860968
Neural plasticity 2020;2020:8860968
Metformin Reduces the Senescence of Renal Tubular Epithelial Cells in Diabetic Nephropathy via the MBNL1/miR-130a-3p/STAT3 Pathway.
Jiang X, Ruan XL, Xue YX, Yang S, Shi M, Wang LN
Oxidative medicine and cellular longevity 2020;2020:8708236
Oxidative medicine and cellular longevity 2020;2020:8708236
Fuzheng Huayu Recipe Prevented and Treated CCl4-Induced Mice Liver Fibrosis through Regulating Polarization and Chemotaxis of Intrahepatic Macrophages via CCL2 and CX3CL1.
Zhang M, Liu HL, Huang K, Peng Y, Tao YY, Zhao CQ, Hu XD, Liu CH
Evidence-based complementary and alternative medicine : eCAM 2020;2020:8591892
Evidence-based complementary and alternative medicine : eCAM 2020;2020:8591892
Trained Innate Immunity by Repeated Low-Dose Lipopolysaccharide Injections Displays Long-Term Neuroprotective Effects.
Zhou XY, Gao R, Hu J, Gao DP, Liao YL, Yang JJ
Mediators of inflammation 2020;2020:8191079
Mediators of inflammation 2020;2020:8191079
Astaxanthin Protects Ochratoxin A-Induced Oxidative Stress and Apoptosis in the Heart via the Nrf2 Pathway.
Cui G, Li L, Xu W, Wang M, Jiao D, Yao B, Xu K, Chen Y, Yang S, Long M, Li P, Guo Y
Oxidative medicine and cellular longevity 2020;2020:7639109
Oxidative medicine and cellular longevity 2020;2020:7639109
Rhein Suppresses Neuroinflammation via Multiple Signaling Pathways in LPS-Stimulated BV2 Microglia Cells.
Zheng P, Tian X, Zhang W, Yang Z, Zhou J, Zheng J, Cui H, Tang T, Luo J, Wang Y
Evidence-based complementary and alternative medicine : eCAM 2020;2020:7210627
Evidence-based complementary and alternative medicine : eCAM 2020;2020:7210627
Adaptive Autophagy Offers Cardiorenal Protection in Rats with Acute Myocardial Infarction.
Feng Z, Jiang HX, Chen H, Liu YN, Wang Y, Yang RB, Han X, Xia CH, Zhu ZB, Shang H, Wu A, Liu WJ
Cardiology research and practice 2020;2020:7158975
Cardiology research and practice 2020;2020:7158975
Anticancer Activity of Tetrandrine by Inducing Apoptosis in Human Breast Cancer Cell Line MDA-MB-231 In Vivo.
Wang CH, Yang JM, Guo YB, Shen J, Pei XH
Evidence-based complementary and alternative medicine : eCAM 2020;2020:6823520
Evidence-based complementary and alternative medicine : eCAM 2020;2020:6823520
Tumor Necrosis Factor Receptor-Associated Protein 1 Protects against Mitochondrial Injury by Preventing High Glucose-Induced mPTP Opening in Diabetes.
Liu L, Zhang L, Zhao J, Guo X, Luo Y, Hu W, Zhao T
Oxidative medicine and cellular longevity 2020;2020:6431517
Oxidative medicine and cellular longevity 2020;2020:6431517
Curcumin Inhibits Proliferation and Epithelial-Mesenchymal Transition in Lens Epithelial Cells through Multiple Pathways.
Liu H, Mao Y, Xia B, Long C, Kuang X, Huang H, Ning J, Ma X, Zhang H, Wang R, Tang H, Du H, Yan J, Zhang Q, Zhang X, Shen H
BioMed research international 2020;2020:6061894
BioMed research international 2020;2020:6061894
Mild Hypothermia Attenuates Hepatic Ischemia-Reperfusion Injury through Regulating the JAK2/STAT3-CPT1a-Dependent Fatty Acid β-Oxidation.
Wang W, Hu X, Xia Z, Liu Z, Zhong Z, Lu Z, Liu A, Ye S, Cao Q, Wang Y, Zhu F, Ye Q
Oxidative medicine and cellular longevity 2020;2020:5849794
Oxidative medicine and cellular longevity 2020;2020:5849794
Plumbagin Enhances the Anticancer Efficacy of Cisplatin by Increasing Intracellular ROS in Human Tongue Squamous Cell Carcinoma.
Xue D, Pan ST, Zhou X, Ye F, Zhou Q, Shi F, He F, Yu H, Qiu J
Oxidative medicine and cellular longevity 2020;2020:5649174
Oxidative medicine and cellular longevity 2020;2020:5649174
NLRC3 Delays the Progression of AD in APP/PS1 Mice via Inhibiting PI3K Activation.
Zha L, Yu Z, Fang J, Zhou L, Guo W, Zhou J
Oxidative medicine and cellular longevity 2020;2020:5328031
Oxidative medicine and cellular longevity 2020;2020:5328031
Protective Effect of Simplicillium sp. Ethyl Acetate Extract against High Glucose-Induced Oxidative Stress in HUVECs.
Tian TT, Li QR, Gan SQ, Chang CR, Shen XC
Evidence-based complementary and alternative medicine : eCAM 2020;2020:5172765
Evidence-based complementary and alternative medicine : eCAM 2020;2020:5172765
The Class III PI3K/Beclin-1 Autophagic Pathway Participates in the mmLDL-Induced Upregulation of ET(A) Receptor in Mouse Mesenteric Arteries.
Xie X, Chen C, Xu CB, Lin J, Cao L, Chen G, Li J
Advances in pharmacological and pharmaceutical sciences 2020;2020:5070436
Advances in pharmacological and pharmaceutical sciences 2020;2020:5070436
Nei Endonuclease VIII-Like1 (NEIL1) Inhibits Apoptosis of Human Colorectal Cancer Cells.
Xue W, Liu Y, Xin N, Miao J, Du J, Wang Y, Shi H, Wei Y, Zhang H, Chen Y, Gao Y, Li D, Feng Y, Yan J, Zhang J, Hou N, Huang C, Han J
BioMed research international 2020;2020:5053975
BioMed research international 2020;2020:5053975
Baicalin Ameliorates Cognitive Impairment and Protects Microglia from LPS-Induced Neuroinflammation via the SIRT1/HMGB1 Pathway.
Li Y, Liu T, Li Y, Han D, Hong J, Yang N, He J, Peng R, Mi X, Kuang C, Zhou Y, Han Y, Shi C, Li Z, Guo X
Oxidative medicine and cellular longevity 2020;2020:4751349
Oxidative medicine and cellular longevity 2020;2020:4751349
Saponin from Periploca forrestii Schltr Mitigates Oxazolone-Induced Atopic Dermatitis via Modulating Macrophage Activation.
Zeng L, Liu Y, Xing C, Huang Y, Sun X, Sun G
Mediators of inflammation 2020;2020:4346367
Mediators of inflammation 2020;2020:4346367
Roux-en-Y Gastric Bypass in Obese Diabetic Rats Promotes Autophagy to Improve Lipid Metabolism through mTOR/p70S6K Signaling Pathway.
Ma N, Ma R, Tang K, Li X, He B
Journal of diabetes research 2020;2020:4326549
Journal of diabetes research 2020;2020:4326549
Obesity-Induced Upregulation of ZBTB7A Promotes Lipid Accumulation through SREBP1.
Zhou JP, Ren YD, Xu QY, Song Y, Zhou F, Chen MY, Liu JJ, Chen LG, Pan JS
BioMed research international 2020;2020:4087928
BioMed research international 2020;2020:4087928
Mining the Prognostic Value of HNRNPAB and Its Function in Breast Carcinoma.
Cao Y, Zhang W, Jin YT, Zou Q
International journal of genomics 2020;2020:3750673
International journal of genomics 2020;2020:3750673
Protective Role of Tangshen Formula on the Progression of Renal Damage in db/db Mice by TRPC6/Talin1 Pathway in Podocytes.
Wang Q, Tian X, Zhou W, Wang Y, Zhao H, Li J, Zhou X, Zhang H, Zhao T, Li P
Journal of diabetes research 2020;2020:3634974
Journal of diabetes research 2020;2020:3634974
Tianma Gouteng Decoction Exerts Cardiovascular Protection by Upregulating OPG and TRAIL in Spontaneously Hypertensive Rats.
Deng LH, Li L, Zhai Y, Michael S, Yang CY, Guo R, Chen SF, Fan GW, Zhao YQ, Liu W
Evidence-based complementary and alternative medicine : eCAM 2020;2020:3439191
Evidence-based complementary and alternative medicine : eCAM 2020;2020:3439191
Quantitative Analysis of the Proteome and the Succinylome in the Thyroid Tissue of High-Fat Diet-Induced Hypothyroxinemia in Rats.
Hu B, Zhao M, Luo D, Yu C, Shao S, Zhao L, Yang Y, Zhang X, Zhao J, Gao L
International journal of endocrinology 2020;2020:3240198
International journal of endocrinology 2020;2020:3240198
Prokineticin 2 (PK2) Rescues Cardiomyocytes from High Glucose/High Palmitic Acid-Induced Damage by Regulating the AKT/GSK3β Pathway In Vitro.
Yang Z, Wu Y, Wang L, Qiu P, Zha W, Yu W
Oxidative medicine and cellular longevity 2020;2020:3163629
Oxidative medicine and cellular longevity 2020;2020:3163629
Anticancer Activity of Modified Tongyou Decoction on Eca109 Esophageal Cancer Cell Invasion and Metastasis through Regulation of the Epithelial-Mesenchymal Transition Mediated by the HIF-1α-Snail Axis.
Jia Y, Yan X, Cao Y, Song W, Zhang G, Hu X
Evidence-based complementary and alternative medicine : eCAM 2020;2020:3053506
Evidence-based complementary and alternative medicine : eCAM 2020;2020:3053506
GDF15 Repression Contributes to 5-Fluorouracil Resistance in Human Colon Cancer by Regulating Epithelial-Mesenchymal Transition and Apoptosis.
Wang B, Ma N, Zheng X, Li X, Ma X, Hu J, Cao B
BioMed research international 2020;2020:2826010
BioMed research international 2020;2020:2826010
Ginsenoside Rg1 Alleviates Podocyte Injury Induced by Hyperlipidemia via Targeting the mTOR/NF-κB/NLRP3 Axis.
Wang T, Gao Y, Yue R, Wang X, Shi Y, Xu J, Wu B, Li Y
Evidence-based complementary and alternative medicine : eCAM 2020;2020:2735714
Evidence-based complementary and alternative medicine : eCAM 2020;2020:2735714
RRS1 Promotes Retinoblastoma Cell Proliferation and Invasion via Activating the AKT/mTOR Signaling Pathway.
Yan X, Wu S, Liu Q, Zhang J
BioMed research international 2020;2020:2420437
BioMed research international 2020;2020:2420437
Posttranslational Modification Defects in Fibroblast Growth Factor Receptor 1 as a Reason for Normosmic Isolated Hypogonadotropic Hypogonadism.
Ying H, Sun Y, Wu H, Jia W, Guan Q, He Z, Gao L, Zhao J, Ji Y, Li G, Xu C
Oxidative medicine and cellular longevity 2020;2020:2358719
Oxidative medicine and cellular longevity 2020;2020:2358719
OSCC Exosomes Regulate miR-210-3p Targeting EFNA3 to Promote Oral Cancer Angiogenesis through the PI3K/AKT Pathway.
Wang H, Wang L, Zhou X, Luo X, Liu K, Jiang E, Chen Y, Shao Z, Shang Z
BioMed research international 2020;2020:2125656
BioMed research international 2020;2020:2125656
Lipin1 Is Involved in the Pathogenesis of Diabetic Encephalopathy through the PKD/Limk/Cofilin Signaling Pathway.
Xie M, Wang M, Liu W, Xu M, Shang P, Jiang D, Ju L, Wu F, Sun A, Yu S, Zhuang X, Chen S
Oxidative medicine and cellular longevity 2020;2020:1723423
Oxidative medicine and cellular longevity 2020;2020:1723423
Emodin Alleviates Hydrogen Peroxide-Induced Inflammation and Oxidative Stress via Mitochondrial Dysfunction by Inhibiting the PI3K/mTOR/GSK3β Pathway in Neuroblastoma SH-SY5Y Cells.
Li R, Liu W, Ou L, Gao F, Li M, Wang L, Wei P, Miao F
BioMed research international 2020;2020:1562915
BioMed research international 2020;2020:1562915
Silencing of PRDX2 Inhibits the Proliferation and Invasion of Non-Small Cell Lung Cancer Cells.
Jing X, Du L, Niu A, Wang Y, Wang Y, Wang C
BioMed research international 2020;2020:1276328
BioMed research international 2020;2020:1276328
Vagus Nerve Stimulation Alleviates Hepatic Ischemia and Reperfusion Injury by Regulating Glutathione Production and Transformation.
Xia H, Liu Z, Liang W, Zeng X, Yang Y, Chen P, Zhong Z, Ye Q
Oxidative medicine and cellular longevity 2020;2020:1079129
Oxidative medicine and cellular longevity 2020;2020:1079129
ADAM10 promotes cell growth, migration, and invasion in osteosarcoma via regulating E-cadherin/β-catenin signaling pathway and is regulated by miR-122-5p.
Yuan Q, Yu H, Chen J, Song X, Sun L
Cancer cell international 2020;20:99
Cancer cell international 2020;20:99
MYC-regulated lncRNA NEAT1 promotes B cell proliferation and lymphomagenesis via the miR-34b-5p-GLI1 pathway in diffuse large B-cell lymphoma.
Qian CS, Li LJ, Huang HW, Yang HF, Wu DP
Cancer cell international 2020;20:87
Cancer cell international 2020;20:87
Alantolactone inhibits cell autophagy and promotes apoptosis via AP2M1 in acute lymphoblastic leukemia.
Shi C, Lan W, Wang Z, Yang D, Wei J, Liu Z, Teng Y, Gu M, Yuan T, Cao F, Zhou J, Li Y
Cancer cell international 2020;20:442
Cancer cell international 2020;20:442
A novel chalcone derivative has antitumor activity in melanoma by inducing DNA damage through the upregulation of ROS products.
Li K, Zhao S, Long J, Su J, Wu L, Tao J, Zhou J, Zhang J, Chen X, Peng C
Cancer cell international 2020;20:36
Cancer cell international 2020;20:36
Downexpression of HSD17B6 correlates with clinical prognosis and tumor immune infiltrates in hepatocellular carcinoma.
Lv L, Zhao Y, Wei Q, Zhao Y, Yi Q
Cancer cell international 2020;20:210
Cancer cell international 2020;20:210
EphA5 knockdown enhances the invasion and migration ability of esophageal squamous cell carcinoma via epithelial-mesenchymal transition through activating Wnt/β-catenin pathway.
Zhang R, Liu J, Zhang W, Hua L, Qian LT, Zhou SB
Cancer cell international 2020;20:20
Cancer cell international 2020;20:20
MicroRNA-196b-5p promotes malignant progression of colorectal cancer by targeting ING5.
Xin H, Wang C, Chi Y, Liu Z
Cancer cell international 2020;20:119
Cancer cell international 2020;20:119
IL-21 promotes osteoblastic differentiation of human valvular interstitial cells through the JAK3/STAT3 pathway.
Liu Z, Wang Y, Shi J, Chen S, Xu L, Li F, Dong N
International journal of medical sciences 2020;17(18):3065-3072
International journal of medical sciences 2020;17(18):3065-3072
Interactome analysis of gene expression profiles identifies CDC6 as a potential therapeutic target modified by miR-215-5p in hepatocellular carcinoma.
Xu H, Huang J, Hua S, Liang L, He X, Zhan M, Lu L, Chu J
International journal of medical sciences 2020;17(18):2926-2940
International journal of medical sciences 2020;17(18):2926-2940
Fine Particulate Matter (PM(2.5)) upregulates expression of Inflammasome NLRP1 via ROS/NF-κB signaling in HaCaT Cells.
Dong L, Hu R, Yang D, Zhao J, Kan H, Tan J, Guan M, Kang Z, Xu F
International journal of medical sciences 2020;17(14):2200-2206
International journal of medical sciences 2020;17(14):2200-2206
Retinal dehydrogenase 5 (RHD5) attenuates metastasis via regulating HIPPO/YAP signaling pathway in Hepatocellular Carcinoma.
Hu H, Xu L, Luo SJ, Xiang T, Chen Y, Cao ZR, Zhang YJ, Mo Z, Wang Y, Meng DF, Yu L, Lin LZ, Zhang SJ
International journal of medical sciences 2020;17(13):1897-1908
International journal of medical sciences 2020;17(13):1897-1908
Polysaccharide extracted from WuGuChong reduces high-fat diet-induced obesity in mice by regulating the composition of intestinal microbiota.
Wang W, Zhong M, Yu T, Chen L, Shi L, Zong J, Wang S
Nutrition & metabolism 2020;17:27
Nutrition & metabolism 2020;17:27
Human follicular fluid proteome reveals association between overweight status and oocyte maturation abnormality.
Liu X, Wang Y, Zhu P, Wang J, Liu J, Li N, Wang W, Zhang W, Zhang C, Wang Y, Shen X, Liu F
Clinical proteomics 2020;17:22
Clinical proteomics 2020;17:22
Wnt5a/CaMKII/ERK/CCL2 axis is required for tumor-associated macrophages to promote colorectal cancer progression.
Liu Q, Song J, Pan Y, Shi D, Yang C, Wang S, Xiong B
International journal of biological sciences 2020;16(6):1023-1034
International journal of biological sciences 2020;16(6):1023-1034
Cdh1 functions as an oncogene by inducing self-renewal of lung cancer stem-like cells via oncogenic pathways.
Ye T, Li J, Sun Z, Liu D, Zeng B, Zhao Q, Wang J, Xing HR
International journal of biological sciences 2020;16(3):447-459
International journal of biological sciences 2020;16(3):447-459
Poly(U) binding splicing factor 60 promotes renal cell carcinoma growth by transcriptionally upregulating telomerase reverse transcriptase.
Long Q, Hua Y, He L, Zhang C, Sui S, Li Y, Qiu H, Tian T, An X, Luo G, Yan Y, Zhao A, Shi D, Xie F, Chen M, Zheng F, Deng W
International journal of biological sciences 2020;16(15):3002-3017
International journal of biological sciences 2020;16(15):3002-3017
Glucocorticoids improve severe or critical COVID-19 by activating ACE2 and reducing IL-6 levels.
Xiang Z, Liu J, Shi D, Chen W, Li J, Yan R, Bi Y, Hu W, Zhu Z, Yu Y, Yang Z
International journal of biological sciences 2020;16(13):2382-2391
International journal of biological sciences 2020;16(13):2382-2391
MFP-FePt-GO Nanocomposites Promote Radiosensitivity of Non-Small Cell Lung Cancer Via Activating Mitochondrial-Mediated Apoptosis and Impairing DNA Damage Repair.
Peng S, Sun Y, Luo Y, Ma S, Sun W, Tang G, Li S, Zhang N, Ren J, Xiao Y, Liu X, Zhang J, Gong Y, Xie C
International journal of biological sciences 2020;16(12):2145-2158
International journal of biological sciences 2020;16(12):2145-2158
Polysaccharides isolated from Cordyceps Sinensis contribute to the progression of NASH by modifying the gut microbiota in mice fed a high-fat diet.
Chen L, Zhang L, Wang W, Qiu W, Liu L, Ning A, Cao J, Huang M, Zhong M
PloS one 2020;15(6):e0232972
PloS one 2020;15(6):e0232972
Effects of miR-103 by negatively regulating SATB2 on proliferation and osteogenic differentiation of human bone marrow mesenchymal stem cells.
Lv H, Yang H, Wang Y
PloS one 2020;15(5):e0232695
PloS one 2020;15(5):e0232695
Decorin knockdown affects the gene expression profile of adhesion, growth and extracellular matrix metabolism in C-28/I2 chondrocytes.
Wang M, Li Z, Zhang M, Wang H, Zhang Y, Feng Y, Liu Y, Chen J
PloS one 2020;15(4):e0232321
PloS one 2020;15(4):e0232321
S100A6 promotes proliferation and migration of HepG2 cells via increased ubiquitin-dependent degradation of p53.
Song D, Xu B, Shi D, Li S, Cai Y
Open medicine (Warsaw, Poland) 2020;15(1):317-326
Open medicine (Warsaw, Poland) 2020;15(1):317-326
TiO(2) Nanoparticles Caused DNA Damage in Lung and Extra-Pulmonary Organs Through ROS-Activated FOXO3a Signaling Pathway After Intratracheal Administration in Rats.
Han B, Pei Z, Shi L, Wang Q, Li C, Zhang B, Su X, Zhang N, Zhou L, Zhao B, Niu Y, Zhang R
International journal of nanomedicine 2020;15:6279-6294
International journal of nanomedicine 2020;15:6279-6294
Anticancer Effects of Zinc Oxide Nanoparticles Through Altering the Methylation Status of Histone on Bladder Cancer Cells.
Zhang T, Du E, Liu Y, Cheng J, Zhang Z, Xu Y, Qi S, Chen Y
International journal of nanomedicine 2020;15:1457-1468
International journal of nanomedicine 2020;15:1457-1468
Cardiac-Specific Caveolin-3 Overexpression Prevents Post-Myocardial Infarction Ventricular Arrhythmias by Inhibiting Ryanodine Receptor-2 Hyperphosphorylation.
Zhang Z, Fang Q, Du T, Chen G, Wang Y, Wang DW
Cardiology 2020;145(3):136-147
Cardiology 2020;145(3):136-147
Upregulation of C Terminus of Hsc70-Interacting Protein Attenuates Apoptosis and Procoagulant Activity and Facilitates Brain Repair After Traumatic Brain Injury.
Chen H, Jing Y, Xu Z, Yang D, Ju S, Guo Y, Tian H, Xue L
Frontiers in neuroscience 2020;14:925
Frontiers in neuroscience 2020;14:925
Oxymatrine Liposomes for Intervertebral Disc Treatment: Formulation, in vitro and vivo Assessments.
Wang H, Ding Y, Zhang W, Wei K, Pei Y, Zou C, Zhang C, Ding J, Fang H, Tan S
Drug design, development and therapy 2020;14:921-931
Drug design, development and therapy 2020;14:921-931
Plasmacytoid Dendritic Cells Protect Against Middle Cerebral Artery Occlusion Induced Brain Injury by Priming Regulatory T Cells.
Chen C, Chencheng Z, Cuiying L, Xiaokun G
Frontiers in cellular neuroscience 2020;14:8
Frontiers in cellular neuroscience 2020;14:8
Neuroprotection Against Parkinson's Disease Through the Activation of Akt/GSK3β Signaling Pathway by Tovophyllin A.
Huang Y, Sun L, Zhu S, Xu L, Liu S, Yuan C, Guo Y, Wang X
Frontiers in neuroscience 2020;14:723
Frontiers in neuroscience 2020;14:723
Neuroprotective Effect of Ketone Metabolism on Inhibiting Inflammatory Response by Regulating Macrophage Polarization After Acute Cervical Spinal Cord Injury in Rats.
Lin J, Huang Z, Liu J, Huang Z, Liu Y, Liu Q, Yang Z, Li R, Wu X, Shi Z, Zhu Q, Wu X
Frontiers in neuroscience 2020;14:583611
Frontiers in neuroscience 2020;14:583611
Effects of Saikosaponin D on CYP1A2 and CYP2D6 in HepaRG Cells.
Li H, Tang Y, Wang Y, Wei W, Yin C, Tang F
Drug design, development and therapy 2020;14:5251-5258
Drug design, development and therapy 2020;14:5251-5258
Combined Transplantation of Olfactory Ensheathing Cells With Rat Neural Stem Cells Enhanced the Therapeutic Effect in the Retina of RCS Rats.
Zhai W, Gao L, Qu L, Li Y, Zeng Y, Li Q, Xu H, Yin ZQ
Frontiers in cellular neuroscience 2020;14:52
Frontiers in cellular neuroscience 2020;14:52
Effect of Platelet-Activating Factor on Barrier Function of ARPE-19 Cells.
Zhang F, Liu L, Zhang H, Liu ZL
Drug design, development and therapy 2020;14:4205-4214
Drug design, development and therapy 2020;14:4205-4214
Metformin Inhibits Propofol-Induced Apoptosis of Mouse Hippocampal Neurons HT-22 Through Downregulating Cav-1.
Ge J, Huang Y, Zhang Y, Liu L, Gu T, Liu X, Yao L, Cai M, Sun J, Song J
Drug design, development and therapy 2020;14:1561-1569
Drug design, development and therapy 2020;14:1561-1569
Bergenin Exerts Hepatoprotective Effects by Inhibiting the Release of Inflammatory Factors, Apoptosis and Autophagy via the PPAR-γ Pathway.
Xiang S, Chen K, Xu L, Wang T, Guo C
Drug design, development and therapy 2020;14:129-143
Drug design, development and therapy 2020;14:129-143
RGFP966 Suppresses Tumor Growth and Migration Through Inhibition of EGFR Expression in Hepatocellular Carcinoma Cells in vitro.
Yu X, Yang F, Jiang H, Fan L
Drug design, development and therapy 2020;14:121-128
Drug design, development and therapy 2020;14:121-128
Cigarette smoke supports stemness and epithelial-mesenchymal transition in bladder cancer stem cells through SHH signaling.
Sun X, Song J, Li E, Geng H, Li Y, Yu D, Zhong C
International journal of clinical and experimental pathology 2020;13(6):1333-1348
International journal of clinical and experimental pathology 2020;13(6):1333-1348
Combination of astragaloside IV and ACEi ameliorates renal injuries in db/db mice.
Zhan H, Han P, Wang M, Wang Y, Weng W, Yu X, Yuan C, Li Y, Shao M, Sun H
International journal of clinical and experimental pathology 2020;13(5):827-836
International journal of clinical and experimental pathology 2020;13(5):827-836
FOXO1 and hsa-microRNA-204-5p affect the biologic behavior of MDA-MB-231 breast cancer cells.
Liang CY, Huang ZG, Tang ZQ, Xiao XL, Zeng JJ, Feng ZB
International journal of clinical and experimental pathology 2020;13(5):1146-1158
International journal of clinical and experimental pathology 2020;13(5):1146-1158
Kin17 knockdown suppresses the migration and invasion of cervical cancer cells through NF-κB-Snail pathway.
Zhong M, Liu Z, Wu K, Hong Z, Zhang Y, Qu J, Zhu C, Ou Z, Zeng T
International journal of clinical and experimental pathology 2020;13(3):607-615
International journal of clinical and experimental pathology 2020;13(3):607-615
Kelch-like protein 14 promotes proliferation and migration of ovarian cancer cells.
Chen Z, Wu M, Liu J
International journal of clinical and experimental pathology 2020;13(12):2950-2961
International journal of clinical and experimental pathology 2020;13(12):2950-2961
Overexpression of EPDR1 has an antitumorigenic effect on breast cancer in vitro.
Liang X, Bai J, Chen B
International journal of clinical and experimental pathology 2020;13(10):2628-2636
International journal of clinical and experimental pathology 2020;13(10):2628-2636
Clinical significance of focal adhesion kinase (FAK) in cervical cancer progression and metastasis.
Chen Y, Hu X, Yang S
International journal of clinical and experimental pathology 2020;13(10):2586-2592
International journal of clinical and experimental pathology 2020;13(10):2586-2592
MicroRNA-451a targets caveolin-1 in stomach cancer cells.
Wang Y, Lin Z, Song J, Wei S, Ye Z, Chen S, Zeng Y, Lin Z, Chen X, Chen L
International journal of clinical and experimental pathology 2020;13(10):2524-2533
International journal of clinical and experimental pathology 2020;13(10):2524-2533
Effect of the SIRT3-AMPK/PPAR pathway on invasion and migration of cervical cancer cells.
Xiao JB, Ma JQ, Yakefu K, Tursun M
International journal of clinical and experimental pathology 2020;13(10):2495-2501
International journal of clinical and experimental pathology 2020;13(10):2495-2501
Acupuncture Targeting SIRT1 in the Hypothalamic Arcuate Nucleus Can Improve Obesity in High-Fat-Diet-Induced Rats with Insulin Resistance via an Anorectic Effect.
Shu Q, Chen L, Wu S, Li J, Liu J, Xiao L, Chen R, Liang F
Obesity facts 2020;13(1):40-57
Obesity facts 2020;13(1):40-57
Circular RNA circNELL2 Acts as the Sponge of miR-127-5p to Promote Esophageal Squamous Cell Carcinoma Progression.
Xiong G, Diao D, Lu D, Liu X, Liu Z, Mai S, Feng S, Dong X, Cai K
OncoTargets and therapy 2020;13:9245-9255
OncoTargets and therapy 2020;13:9245-9255
TDO Promotes Hepatocellular Carcinoma Progression.
Li S, Li L, Wu J, Song F, Qin Z, Hou L, Xiao C, Weng J, Qin X, Xu J
OncoTargets and therapy 2020;13:5845-5855
OncoTargets and therapy 2020;13:5845-5855
TMED3 Promotes Proliferation and Migration in Breast Cancer Cells by Activating Wnt/β-Catenin Signaling.
Zhang X, Luo Y, Li Q
OncoTargets and therapy 2020;13:5819-5830
OncoTargets and therapy 2020;13:5819-5830
Characterization of Triple-Negative Breast Cancer MDA-MB-231 Cell Spheroid Model.
Huang Z, Yu P, Tang J
OncoTargets and therapy 2020;13:5395-5405
OncoTargets and therapy 2020;13:5395-5405
β-Elemene Enhances the Chemotherapeutic Effect of 5-Fluorouracil in Triple-Negative Breast Cancer via PI3K/AKT, RAF-MEK-ErK, and NF-κB Signaling Pathways.
Su P, Ahmad B, Zou K, Zou L
OncoTargets and therapy 2020;13:5207-5222
OncoTargets and therapy 2020;13:5207-5222
Diosgenin and GSK126 Produce Synergistic Effects on Epithelial-Mesenchymal Transition in Gastric Cancer Cells by Mediating EZH2 via the Rho/ROCK Signaling Pathway.
Liu S, Rong G, Li X, Geng L, Zeng Z, Jiang D, Yang J, Wei Y
OncoTargets and therapy 2020;13:5057-5067
OncoTargets and therapy 2020;13:5057-5067
Comprehensive Transcriptomic Analysis and Experimental Validation Identify lncRNA HOXA-AS2/miR-184/COL6A2 as the Critical ceRNA Regulation Involved in Low-Grade Glioma Recurrence.
Chen PY, Li XD, Ma WN, Li H, Li MM, Yang XY, Li SY
OncoTargets and therapy 2020;13:4999-5016
OncoTargets and therapy 2020;13:4999-5016
miR-877-5p Suppresses Gastric Cancer Cell Proliferation Through Targeting FOXM1.
Wu K, Yu Z, Tang Z, Wei W, Xie D, Xie Y, Xiao Q
OncoTargets and therapy 2020;13:4731-4742
OncoTargets and therapy 2020;13:4731-4742
FANCI Cooperates with IMPDH2 to Promote Lung Adenocarcinoma Tumor Growth via a MEK/ERK/MMPs Pathway.
Zheng P, Li L
OncoTargets and therapy 2020;13:451-463
OncoTargets and therapy 2020;13:451-463
DNMT1 Enhances the Radiosensitivity of HPV-Positive Head and Neck Squamous Cell Carcinomas via Downregulating SMG1.
Zhang C, Mi J, Deng Y, Deng Z, Long D, Liu Z
OncoTargets and therapy 2020;13:4201-4211
OncoTargets and therapy 2020;13:4201-4211
Microsatellite Instability-Related ACVR2A Mutations Partially Account for Decreased Lymph Node Metastasis in MSI-H Gastric Cancers.
Zhao L, Zhang J, Qu X, Yang Y, Gong Z, Yang Y, Wu Z, Guo W
OncoTargets and therapy 2020;13:3809-3821
OncoTargets and therapy 2020;13:3809-3821
GPR30 Promotes the Phenotypic Switching of Vascular Smooth Muscle Cells via Activating the AKT and ERK Pathways.
Zha B, Qiu P, Zhang C, Li X, Chen Z
OncoTargets and therapy 2020;13:3801-3808
OncoTargets and therapy 2020;13:3801-3808
Low-Dose Radiation Promotes Invasion and Migration of A549 Cells by Activating the CXCL1/NF-κB Signaling Pathway.
Li J, Wu DM, Han R, Yu Y, Deng SH, Liu T, Zhang T, Xu Y
OncoTargets and therapy 2020;13:3619-3629
OncoTargets and therapy 2020;13:3619-3629
Cbl Proto-Oncogene B (CBLB) c.197A>T Mutation Induces Mild Metabolic Dysfunction in Partial Type I Multiple Symmetric Lipomatosis (MSL).
Chen K, Wan X, Zhao L, Zhao S, Peng L, Yang W, Yuan J, Zhu L, Mo Z
Diabetes, metabolic syndrome and obesity : targets and therapy 2020;13:3535-3549
Diabetes, metabolic syndrome and obesity : targets and therapy 2020;13:3535-3549
RCC2 Interacts with Small GTPase RalA and Regulates Cell Proliferation and Motility in Gastric Cancer.
Wang P, Zhang W, Wang L, Liang W, Cai A, Gao Y, Chen L
OncoTargets and therapy 2020;13:3093-3103
OncoTargets and therapy 2020;13:3093-3103
RSF-1 siRNA Enhances Tumor Radiosensitivity in Cervical Cancer via Enhanced DNA Damage, Cell Cycle Redistribution, and Promotion of Apoptosis.
Tian J, Kong E, Wang X, Xie Z, Chang CY, Sheu JJ, Hao Q, Sun L
OncoTargets and therapy 2020;13:3061-3071
OncoTargets and therapy 2020;13:3061-3071
Long Non-Coding RNA SPRY4-IT1 Reverses Cisplatin Resistance by Downregulating MPZL-1 via Suppressing EMT in NSCLC.
Ye Y, Gu J, Liu P, Wang H, Jiang L, Lei T, Yu S, Han G, Wang Z
OncoTargets and therapy 2020;13:2783-2793
OncoTargets and therapy 2020;13:2783-2793
Tumor Suppressor microRNA-138 Suppresses Low-Grade Glioma Development and Metastasis via Regulating IGF2BP2.
Yang Y, Liu X, Cheng L, Li L, Wei Z, Wang Z, Han G, Wan X, Wang Z, Zhang J, Chen C
OncoTargets and therapy 2020;13:2247-2260
OncoTargets and therapy 2020;13:2247-2260
Circular RNA 0001313 Knockdown Suppresses Non-Small Cell Lung Cancer Cell Proliferation and Invasion via the microRNA-452/HMGB3/ERK/MAPK Axis.
Zhang S, Liu J, Yuan T, Liu H, Wan C, Le Y
International journal of general medicine 2020;13:1495-1507
International journal of general medicine 2020;13:1495-1507
Knockdown of Circular RNA Hsa_circ_0000714 Can Regulate RAB17 by Sponging miR-370-3p to Reduce Paclitaxel Resistance of Ovarian Cancer Through CDK6/RB Pathway.
Guo M, Li S, Zhao X, Yuan Y, Zhang B, Guan Y
OncoTargets and therapy 2020;13:13211-13224
OncoTargets and therapy 2020;13:13211-13224
DUSP9 Suppresses Proliferation and Migration of Clear Cell Renal Cell Carcinoma via the mTOR Pathway.
Luo J, Luo X, Liu X, Fang Z, Xu J, Li L
OncoTargets and therapy 2020;13:1321-1330
OncoTargets and therapy 2020;13:1321-1330
Hsa_circRNA_100146 Acts as a Sponge of miR-149-5p in Promoting Bladder Cancer Progression via Regulating RNF2.
Wang H, Niu X, Mao F, Liu X, Zhong B, Jiang H, Fu G
OncoTargets and therapy 2020;13:11007-11017
OncoTargets and therapy 2020;13:11007-11017
Overexpression of RNF126 Promotes the Development of Colorectal Cancer via Enhancing p53 Ubiquitination and Degradation.
Wang S, Wang T, Wang L, Zhong L, Li K
OncoTargets and therapy 2020;13:10917-10929
OncoTargets and therapy 2020;13:10917-10929
17-Allylamino-Demethoxygeldanamycin Ameliorate Microthrombosis Via HSP90/RIP3/NLRP3 Pathway After Subarachnoid Hemorrhage in Rats.
Zuo Y, He T, Liao P, Zhuang K, Yan X, Liu F
Acta neurochirurgica. Supplement 2020;127:69-75
Acta neurochirurgica. Supplement 2020;127:69-75
lncRNA USP2-AS1 promotes colon cancer progression by modulating Hippo/YAP1 signaling.
Li D, Bao J, Yao J, Li J
American journal of translational research 2020;12(9):5670-5682
American journal of translational research 2020;12(9):5670-5682
β-catenin regulates myocardial ischemia/reperfusion injury following heterotopic heart transplantation in mice by modulating PTEN pathways.
Ban Q, Qiao L, Xia H, Xie B, Liu J, Ma Y, Zhang L, Zhang M, Liu LG, Jiao W, Yang S, Li Z, Zheng S, Liu D, Xia J, Qi Z
American journal of translational research 2020;12(8):4757-4771
American journal of translational research 2020;12(8):4757-4771
Homocysteine-induced electrical remodeling via the mediation of IP(3)R1/Nav1.5 signaling pathway.
Han L, Wu A, Li Q, Xia Z, Wu Y, Hong K, Xia Z, Li J
American journal of translational research 2020;12(7):3822-3841
American journal of translational research 2020;12(7):3822-3841
Astragaloside IV alleviates puromycin aminonucleoside-induced podocyte cytoskeleton injury through the Wnt/PCP pathway.
Zeng Y, Zhang B, Liu X, He L, Wang T, Yu X, Kang Y, Li S
American journal of translational research 2020;12(7):3512-3521
American journal of translational research 2020;12(7):3512-3521
CircAPLP2 regulates the proliferation and metastasis of colorectal cancer by targeting miR-101-3p to activate the Notch signalling pathway.
Wu HB, Huang SS, Lu CG, Tian SD, Chen M
American journal of translational research 2020;12(6):2554-2569
American journal of translational research 2020;12(6):2554-2569
Huangqi-Danshen decoction alleviates diabetic nephropathy in db/db mice by inhibiting PINK1/Parkin-mediated mitophagy.
Liu X, Lu J, Liu S, Huang D, Chen M, Xiong G, Li S
American journal of translational research 2020;12(3):989-998
American journal of translational research 2020;12(3):989-998
Kaempferol attenuated cisplatin-induced cardiac injury via inhibiting STING/NF-κB-mediated inflammation.
Qi Y, Ying Y, Zou J, Fang Q, Yuan X, Cao Y, Cai Y, Fu S
American journal of translational research 2020;12(12):8007-8018
American journal of translational research 2020;12(12):8007-8018
Enzastaurin enhances ATRA-induced differentiation of acute myeloid leukemia cells.
Li ZY, Liang C, Ding M, Weng XQ, Sheng Y, Wu J, Lu H, Cai X
American journal of translational research 2020;12(12):7836-7854
American journal of translational research 2020;12(12):7836-7854
Polydopamine coating with static magnetic field promotes the osteogenic differentiation of human bone-derived mesenchymal stem cells on three-dimensional printed porous titanium scaffolds by upregulation of the BMP-Smads signaling pathway.
Kong L, Han Y, Lu Q, Zhou D, Wang B, Wang D, Zhang W, Xiang H, Li M, Wang F
American journal of translational research 2020;12(12):7812-7825
American journal of translational research 2020;12(12):7812-7825
EphA5 Silencing Increases the Radiosensitivity of ESCC Cells Through ATM-Dependent Pathway.
Zhang R, Han D, Li L, Luo W, Liu J, Qian L
Cancer management and research 2020;12:9539-9549
Cancer management and research 2020;12:9539-9549
miR-758-3p Inhibits Proliferation, Migration, and Invasion of Clear Cell Renal Cell Carcinoma and Predicts Favorable Prognosis.
Wu Y, Liu Y
Cancer management and research 2020;12:9285-9295
Cancer management and research 2020;12:9285-9295
Exosome-Reversed Chemoresistance to Cisplatin in Non-Small Lung Cancer Through Transferring miR-613.
Li D, Meng D, Niu R
Cancer management and research 2020;12:7961-7972
Cancer management and research 2020;12:7961-7972
miR-31-5p Regulates 14-3-3 ɛ to Inhibit Prostate Cancer 22RV1 Cell Survival and Proliferation via PI3K/AKT/Bcl-2 Signaling Pathway.
Zhao J, Xu H, Duan Z, Chen X, Ao Z, Chen Y, Ruan Y, Ni M
Cancer management and research 2020;12:6679-6694
Cancer management and research 2020;12:6679-6694
MiTF is Associated with Chemoresistance to Cisplatin in A549 Lung Cancer Cells via Modulating Lysosomal Biogenesis and Autophagy.
Li W, Qin X, Wang B, Xu G, Zhang J, Jiang X, Chen C, Qiu F, Zou Z
Cancer management and research 2020;12:6563-6573
Cancer management and research 2020;12:6563-6573
Class I HDAC Inhibitor Improves Synaptic Proteins and Repairs Cytoskeleton Through Regulating Synapse-Related Genes In vitro and In vivo.
Han Y, Chen L, Guo Y, Wang C, Zhang C, Kong L, Ma H
Frontiers in aging neuroscience 2020;12:619866
Frontiers in aging neuroscience 2020;12:619866
FTY720 Prevents Spatial Memory Impairment in a Rat Model of Chronic Cerebral Hypoperfusion via a SIRT3-Independent Pathway.
Zhang M, Hu Y, Zhang J, Zhang J
Frontiers in aging neuroscience 2020;12:593364
Frontiers in aging neuroscience 2020;12:593364
The Requirement of the C-Terminal Domain of GluA1 in Different Forms of Long-Term Potentiation in the Hippocampus Is Age-Dependent.
Liu A, Ji H, Ren Q, Meng Y, Zhang H, Collingride G, Xie W, Jia Z
Frontiers in synaptic neuroscience 2020;12:588785
Frontiers in synaptic neuroscience 2020;12:588785
Glucosamine-6-Phosphate Isomerase 1 Promotes Tumor Progression and Indicates Poor Prognosis in Hepatocellular Carcinoma.
Li D, Cheng X, Zheng W, Chen J
Cancer management and research 2020;12:4923-4935
Cancer management and research 2020;12:4923-4935
Down-regulation of USP8 Inhibits Cholangiocarcinoma Cell Proliferation and Invasion.
Jing X, Chen Y, Chen Y, Shi G, Lv S, Cheng N, Feng C, Xin Z, Zhang L, Wu J
Cancer management and research 2020;12:2185-2194
Cancer management and research 2020;12:2185-2194
AOC1 Contributes to Tumor Progression by Promoting the AKT and EMT Pathways in Gastric Cancer.
Xu F, Xu Y, Xiong JH, Zhang JH, Wu J, Luo J, Xiong JP
Cancer management and research 2020;12:1789-1798
Cancer management and research 2020;12:1789-1798
MicroRNA-1276 Promotes Colon Cancer Cell Proliferation by Negatively Regulating LACTB.
Wang C, Shi Z, Hong Z, Pan J, Chen Z, Qiu C, Zhuang H, Zheng X
Cancer management and research 2020;12:12185-12195
Cancer management and research 2020;12:12185-12195
Hyperin Controls the Development and Therapy of Gastric Cancer via Regulating Wnt/β-Catenin Signaling.
Ping MH
Cancer management and research 2020;12:11773-11782
Cancer management and research 2020;12:11773-11782
MicroRNA-802 Suppresses Tumorigenesis of Colorectal Cancer via Regulating UBN2.
Yang T, Guo Q, Li D, Bai G, Sun H, Wang W
Cancer management and research 2020;12:11219-11230
Cancer management and research 2020;12:11219-11230
miR-302e Suppresses Glioma Progression by Targeting VEGFA.
Xie Y, Liu X, Hu T, Wang W
Cancer management and research 2020;12:10965-10974
Cancer management and research 2020;12:10965-10974
Exosomes derived from 5-fluorouracil-resistant colon cancer cells are enriched in GDF15 and can promote angiogenesis.
Zheng X, Ma N, Wang X, Hu J, Ma X, Wang J, Cao B
Journal of Cancer 2020;11(24):7116-7126
Journal of Cancer 2020;11(24):7116-7126
NFE2L3 promotes malignant behavior and EMT of human hepatocellular carcinoma (HepG2) cells via Wnt/β‑catenin pathway.
Ren Y, Wang Y, Hao S, Yang Y, Xiong W, Qiu L, Tao J, Tang A
Journal of Cancer 2020;11(23):6939-6949
Journal of Cancer 2020;11(23):6939-6949
Ligand-independent EphB1 signaling mediates TGF-β-activated CDH2 and promotes lung cancer cell invasion and migration.
Wang L, Peng Q, Sai B, Zheng L, Xu J, Yin N, Feng X, Xiang J
Journal of Cancer 2020;11(14):4123-4131
Journal of Cancer 2020;11(14):4123-4131
Analysis of Differentially Expressed Genes in a Chinese Cohort of Esophageal Squamous Cell Carcinoma.
Liu G, Zhao Y, Chen H, Jia J, Cheng X, Wang F, Ji Q, Thorne RF, Chen S, Liu X
Journal of Cancer 2020;11(13):3783-3793
Journal of Cancer 2020;11(13):3783-3793
Caffeic Acid Phenethyl Ester Ameliorates Calcification by Inhibiting Activation of the AKT/NF-κB/NLRP3 Inflammasome Pathway in Human Aortic Valve Interstitial Cells.
Liu M, Li F, Huang Y, Zhou T, Chen S, Li G, Shi J, Dong N, Xu K
Frontiers in pharmacology 2020;11:826
Frontiers in pharmacology 2020;11:826
UVA Induced Oxidative Stress Was Inhibited by Paeoniflorin/Nrf2 Signaling or PLIN2.
Lu YS, Jiang Y, Yuan JP, Jiang SB, Yang Y, Zhu PY, Sun YZ, Qi RQ, Liu T, Wang HX, Wu Y, Gao XH, Chen HD
Frontiers in pharmacology 2020;11:736
Frontiers in pharmacology 2020;11:736
Gelatinases Cleave Dentin Sialoprotein Intracellularly.
Gou X, Xue Y, Zheng H, Yang G, Chen S, Chen Z, Yuan G
Frontiers in physiology 2020;11:686
Frontiers in physiology 2020;11:686
Salvianolic Acid A Has Anti-Osteoarthritis Effect In Vitro and In Vivo.
Wu Y, Wang Z, Lin Z, Fu X, Zhan J, Yu K
Frontiers in pharmacology 2020;11:682
Frontiers in pharmacology 2020;11:682
Notch3 Modulates Cardiac Fibroblast Proliferation, Apoptosis, and Fibroblast to Myofibroblast Transition via Negative Regulation of the RhoA/ROCK/Hif1α Axis.
Shi J, Xiao P, Liu X, Chen Y, Xu Y, Fan J, Yin Y
Frontiers in physiology 2020;11:669
Frontiers in physiology 2020;11:669
Obg-Like ATPase 1 Enhances Chemoresistance of Breast Cancer via Activation of TGF-β/Smad Axis Cascades.
Liu J, Miao X, Xiao B, Huang J, Tao X, Zhang J, Zhao H, Pan Y, Wang H, Gao G, Xiao GG
Frontiers in pharmacology 2020;11:666
Frontiers in pharmacology 2020;11:666
Ursolic Acid Regulates Cell Cycle and Proliferation in Colon Adenocarcinoma by Suppressing Cyclin B1.
Yang M, Hu C, Cao Y, Liang W, Yang X, Xiao T
Frontiers in pharmacology 2020;11:622212
Frontiers in pharmacology 2020;11:622212
Pristimerin Suppresses RANKL-Induced Osteoclastogenesis and Ameliorates Ovariectomy-Induced Bone Loss.
Qi D, Liu H, Sun X, Luo D, Zhu M, Tao T, Gao C, Zhou C, Zhou W, Xiao J
Frontiers in pharmacology 2020;11:621110
Frontiers in pharmacology 2020;11:621110
Integrating Network Pharmacology and Experimental Validation to Investigate the Effects and Mechanism of Astragalus Flavonoids Against Hepatic Fibrosis.
An L, Lin Y, Li L, Kong M, Lou Y, Wu J, Liu Z
Frontiers in pharmacology 2020;11:618262
Frontiers in pharmacology 2020;11:618262
Butylphthalide Inhibits Autophagy and Promotes Multiterritory Perforator Flap Survival.
Li B, Chen Z, Luo X, Zhang C, Chen H, Wang S, Zhao M, Ma H, Liu J, Cheng M, Yang Y, Yan H
Frontiers in pharmacology 2020;11:612932
Frontiers in pharmacology 2020;11:612932
Role of GABRD Gene Methylation in the Nucleus Accumbens in Heroin-Seeking Behavior in Rats.
Hong Q, Xu W, Lin Z, Liu J, Chen W, Zhu H, Lai M, Zhuang D, Xu Z, Fu D, Zhou W, Liu H
Frontiers in pharmacology 2020;11:612200
Frontiers in pharmacology 2020;11:612200
Elucidation of the Mechanism of Action of Ginseng Against Acute Lung Injury/Acute Respiratory Distress Syndrome by a Network Pharmacology-Based Strategy.
Ding Q, Zhu W, Diao Y, Xu G, Wang L, Qu S, Shi Y
Frontiers in pharmacology 2020;11:611794
Frontiers in pharmacology 2020;11:611794
Isorhamnetin Enhances the Radiosensitivity of A549 Cells Through Interleukin-13 and the NF-κB Signaling Pathway.
Du Y, Jia C, Liu Y, Li Y, Wang J, Sun K
Frontiers in pharmacology 2020;11:610772
Frontiers in pharmacology 2020;11:610772
A Rare KIF1A Missense Mutation Enhances Synaptic Function and Increases Seizure Activity.
Guo Y, Chen Y, Yang M, Xu X, Lin Z, Ma J, Chen H, Hu Y, Ma Y, Wang X, Tian X
Frontiers in genetics 2020;11:61
Frontiers in genetics 2020;11:61
Oleoylethanolamide Protects Against Acute Liver Injury by Regulating Nrf-2/HO-1 and NLRP3 Pathways in Mice.
Hu J, Zhu Z, Ying H, Yao J, Ma H, Li L, Zhao Y
Frontiers in pharmacology 2020;11:605065
Frontiers in pharmacology 2020;11:605065
Stimulation of Vibratory Urticaria-Associated Adhesion-GPCR, EMR2/ADGRE2, Triggers the NLRP3 Inflammasome Activation Signal in Human Monocytes.
I KY, Tseng WY, Wang WC, Gordon S, Ng KF, Lin HH
Frontiers in immunology 2020;11:602016
Frontiers in immunology 2020;11:602016
Isoquercitrin Ameliorates Cisplatin-Induced Nephrotoxicity Via the Inhibition of Apoptosis, Inflammation, and Oxidative Stress.
Wang H, Xia W, Long G, Pei Z, Li Y, Wu M, Wang Q, Zhang Y, Jia Z, Chen H
Frontiers in pharmacology 2020;11:599416
Frontiers in pharmacology 2020;11:599416
Poly(dA:dT) Suppresses HSV-2 Infection of Human Cervical Epithelial Cells Through RIG-I Activation.
Shao DD, Meng FZ, Liu Y, Xu XQ, Wang X, Hu WH, Hou W, Ho WZ
Frontiers in immunology 2020;11:598884
Frontiers in immunology 2020;11:598884
A Longitudinal Study of T2 Mapping Combined With Diffusion Tensor Imaging to Quantitatively Evaluate Tissue Repair of Rat Skeletal Muscle After Frostbite.
Gao Y, Lu Z, Lyu X, Liu Q, Pan S
Frontiers in physiology 2020;11:597638
Frontiers in physiology 2020;11:597638
Human Umbilical Cord Mesenchymal Stem Cell Differentiation Into Odontoblast-Like Cells and Endothelial Cells: A Potential Cell Source for Dental Pulp Tissue Engineering.
Zhang S, Zhang W, Li Y, Ren L, Deng H, Yin X, Gao X, Pan S, Niu Y
Frontiers in physiology 2020;11:593
Frontiers in physiology 2020;11:593
Tanshinone IIA Inhibits Epithelial-to-Mesenchymal Transition Through Hindering β-Arrestin1 Mediated β-Catenin Signaling Pathway in Colorectal Cancer.
Song Q, Yang L, Han Z, Wu X, Li R, Zhou L, Liu N, Sui H, Cai J, Wang Y, Ji Q, Li Q
Frontiers in pharmacology 2020;11:586616
Frontiers in pharmacology 2020;11:586616
MiR-497-5p Regulates Osteo/Odontogenic Differentiation of Stem Cells From Apical Papilla via the Smad Signaling Pathway by Targeting Smurf2.
Liu J, Wang X, Song M, Du J, Yu J, Zheng W, Zhang C, Wang Y
Frontiers in genetics 2020;11:582366
Frontiers in genetics 2020;11:582366
A Novel Transcript Isoform of TBK1 Negatively Regulates Type I IFN Production by Promoting Proteasomal Degradation of TBK1 and Lysosomal Degradation of IRF3.
Zhang J, Wu XM, Hu YW, Chang MX
Frontiers in immunology 2020;11:580864
Frontiers in immunology 2020;11:580864
Seneca Valley Virus 3C Protease Inhibits Stress Granule Formation by Disrupting eIF4GI-G3BP1 Interaction.
Wen W, Zhao Q, Yin M, Qin L, Hu J, Chen H, Li X, Qian P
Frontiers in immunology 2020;11:577838
Frontiers in immunology 2020;11:577838
Evodiamine Attenuates Experimental Colitis Injury Via Activating Autophagy and Inhibiting NLRP3 Inflammasome Assembly.
Ding W, Ding Z, Wang Y, Zhu Y, Gao Q, Cao W, Du R
Frontiers in pharmacology 2020;11:573870
Frontiers in pharmacology 2020;11:573870
Chidamide Inhibits Acute Myeloid Leukemia Cell Proliferation by lncRNA VPS9D1-AS1 Downregulation via MEK/ERK Signaling Pathway.
Lin L, Que Y, Lu P, Li H, Xiao M, Zhu X, Li D
Frontiers in pharmacology 2020;11:569651
Frontiers in pharmacology 2020;11:569651
Transcriptomic Analysis of Glycolysis-Related Genes Reveals an Independent Signature of Bladder Carcinoma.
Mou Z, Yang C, Zhang Z, Wu S, Xu C, Cheng Z, Dai X, Chen X, Ou Y, Jiang H
Frontiers in genetics 2020;11:566918
Frontiers in genetics 2020;11:566918
Sleep Deprivation Induces Cognitive Impairment by Increasing Blood-Brain Barrier Permeability via CD44.
Sun J, Wu J, Hua F, Chen Y, Zhan F, Xu G
Frontiers in neurology 2020;11:563916
Frontiers in neurology 2020;11:563916
Protective effects of taurine against muscle damage induced by diquat in 35 days weaned piglets.
Wen C, Li F, Guo Q, Zhang L, Duan Y, Wang W, Li J, He S, Chen W, Yin Y
Journal of animal science and biotechnology 2020;11:56
Journal of animal science and biotechnology 2020;11:56
The Endogenous Alterations of the Gut Microbiota and Feces Metabolites Alleviate Oxidative Damage in the Brain of LanCL1 Knockout Mice.
Zhang F, Qi N, Zeng Y, Bao M, Chen Y, Liao J, Wei L, Cao D, Huang S, Luo Q, Jiang Y, Mo Z
Frontiers in microbiology 2020;11:557342
Frontiers in microbiology 2020;11:557342
Protective Effects and Possible Mechanisms of Actions of Bushen Cuyun Recipe on Diminished Ovarian Reserve Induced by Cyclophosphamide in Rats.
Jiang M, Wang W, Zhang J, Wang C, Bi Y, Li P, Yang S, Li J, Xu YT, Wang T
Frontiers in pharmacology 2020;11:546
Frontiers in pharmacology 2020;11:546
Mechanical Stretch Induces Smooth Muscle Cell Dysfunction by Regulating ACE2 via P38/ATF3 and Post-transcriptional Regulation by miR-421.
Liu X, Liu X, Li M, Zhang Y, Chen W, Zhang M, Zhang C, Zhang M
Frontiers in physiology 2020;11:540591
Frontiers in physiology 2020;11:540591
Hepatitis B Core Antigen Impairs the Polarization While Promoting the Production of Inflammatory Cytokines of M2 Macrophages via the TLR2 Pathway.
Yi H, Zhang Y, Yang X, Li M, Hu H, Xiong J, Wang N, Jin J, Zhang Y, Song Y, Wang X, Chen L, Lian J
Frontiers in immunology 2020;11:535
Frontiers in immunology 2020;11:535
Investigation of the Lipid-Lowering Mechanisms and Active Ingredients of Danhe Granule on Hyperlipidemia Based on Systems Pharmacology.
Chen K, Ma Z, Yan X, Liu J, Xu W, Li Y, Dai Y, Zhang Y, Xiao H
Frontiers in pharmacology 2020;11:528
Frontiers in pharmacology 2020;11:528
Lian Hua Qing Wen Capsules, a Potent Epithelial Protector in Acute Lung Injury Model, Block Proapoptotic Communication Between Macrophages, and Alveolar Epithelial Cells.
Li Q, Ran Q, Sun L, Yin J, Luo T, Liu L, Zhao Z, Yang Q, Li Y, Chen Y, Weng X, Wang Y, Cai W, Zhu X
Frontiers in pharmacology 2020;11:522729
Frontiers in pharmacology 2020;11:522729
Differential Expression and Alternative Splicing of Transcripts Associated With Cisplatin-Induced Chemoresistance in Nasopharyngeal Carcinoma.
Zhang J, Jiang H, Xie T, Zheng J, Tian Y, Li R, Wang B, Lin J, Xu A, Huang X, Yuan Y
Frontiers in genetics 2020;11:52
Frontiers in genetics 2020;11:52
Fibroblast Growth Factor 1 Ameliorates Diabetes-Induced Liver Injury by Reducing Cellular Stress and Restoring Autophagy.
Xu Z, Wu Y, Wang F, Li X, Wang P, Li Y, Wu J, Li Y, Jiang T, Pan X, Zhang X, Xie L, Xiao J, Liu Y
Frontiers in pharmacology 2020;11:52
Frontiers in pharmacology 2020;11:52
C-X-C Motif Chemokine 10 Contributes to the Development of Neuropathic Pain by Increasing the Permeability of the Blood-Spinal Cord Barrier.
Li HL, Huang Y, Zhou YL, Teng RH, Zhou SZ, Lin JP, Yang Y, Zhu SM, Xu H, Yao YX
Frontiers in immunology 2020;11:477
Frontiers in immunology 2020;11:477
Antimicrobial Role of RNASET2 Protein During Innate Immune Response in the Medicinal Leech Hirudo verbana.
Baranzini N, De Vito A, Orlandi VT, Reguzzoni M, Monti L, de Eguileor M, Rosini E, Pollegioni L, Tettamanti G, Acquati F, Grimaldi A
Frontiers in immunology 2020;11:370
Frontiers in immunology 2020;11:370
Single-Anastomosis Duodenal Jejunal Bypass Improve Glucose Metabolism by Regulating Gut Microbiota and Short-Chain Fatty Acids in Goto-Kakisaki Rats.
Yu X, Wu Z, Song Z, Zhang H, Zhan J, Yu H, Huang H, Yang B, Xie L, Dai X, Zhao W, Yu J, Wu L
Frontiers in microbiology 2020;11:273
Frontiers in microbiology 2020;11:273
Reduced Let-7f in Bone Marrow-Derived Mesenchymal Stem Cells Triggers Treg/Th17 Imbalance in Patients With Systemic Lupus Erythematosus.
Geng L, Tang X, Wang S, Sun Y, Wang D, Tsao BP, Feng X, Sun L
Frontiers in immunology 2020;11:233
Frontiers in immunology 2020;11:233
Tilianin Extracted From Dracocephalum moldavica L. Induces Intrinsic Apoptosis and Drives Inflammatory Microenvironment Response on Pharyngeal Squamous Carcinoma Cells via Regulating TLR4 Signaling Pathways.
Jiang H, Zeng L, Dong X, Guo S, Xing J, Li Z, Liu R
Frontiers in pharmacology 2020;11:205
Frontiers in pharmacology 2020;11:205
HPV16 E6/E7 promote the translocation and glucose uptake of GLUT1 by PI3K/AKT pathway via relieving miR-451 inhibitory effect on CAB39 in lung cancer cells.
Wang HM, Lu YJ, He L, Gu NJ, Wang SY, Qiu XS, Wang EH, Wu GP
Therapeutic advances in chronic disease 2020;11:2040622320957143
Therapeutic advances in chronic disease 2020;11:2040622320957143
Scutellarein inhibits BLM-mediated pulmonary fibrosis by affecting fibroblast differentiation, proliferation, and apoptosis.
Miao K, Pan T, Mou Y, Zhang L, Xiong W, Xu Y, Yu J, Wang Y
Therapeutic advances in chronic disease 2020;11:2040622320940185
Therapeutic advances in chronic disease 2020;11:2040622320940185
Critical Role of AdipoR1 in Regulating Th17 Cell Differentiation Through Modulation of HIF-1α-Dependent Glycolysis.
Zhang Q, Wang L, Jiang J, Lin S, Luo A, Zhao P, Tan W, Zhang M
Frontiers in immunology 2020;11:2040
Frontiers in immunology 2020;11:2040
Treatment and Prevention of Lung Cancer Using a Virus-Infected Reprogrammed Somatic Cell-Derived Tumor Cell Vaccination (VIReST) Regime.
Zhang Z, Lu S, Dunmall LSC, Wang Z, Cheng Z, Zhang Z, Yan W, Chu Y, Gao D, Wang N, Li Y, Wang J, Li Y, Ji Y, Shan D, Li K, Wang P, Dong Y, Dong J, Lemoine NR, Pei D, Zhang L, Wang Y
Frontiers in immunology 2020;11:1996
Frontiers in immunology 2020;11:1996
MiR-362-5p, Which Is Regulated by Long Non-Coding RNA MBNL1-AS1, Promotes the Cell Proliferation and Tumor Growth of Bladder Cancer by Targeting QKI.
Wei X, Wang B, Wang Q, Yang X, Yang Y, Fang Z, Yi C, Shi L, Fan X, Tao J, Guo Y, Song D
Frontiers in pharmacology 2020;11:164
Frontiers in pharmacology 2020;11:164
Csf2 Attenuated Sepsis-Induced Acute Kidney Injury by Promoting Alternative Macrophage Transition.
Li Y, Zhai P, Zheng Y, Zhang J, Kellum JA, Peng Z
Frontiers in immunology 2020;11:1415
Frontiers in immunology 2020;11:1415
Combined Proteome and Transcriptome Analysis of Heat-Primed Azalea Reveals New Insights Into Plant Heat Acclimation Memory.
Wang X, Li Z, Liu B, Zhou H, Elmongy MS, Xia Y
Frontiers in plant science 2020;11:1278
Frontiers in plant science 2020;11:1278
Maimendong Decoction Improves Pulmonary Function in Rats With Idiopathic Pulmonary Fibrosis by Inhibiting Endoplasmic Reticulum Stress in AECIIs.
Shen M, Nan Y, Zhang L, Di L, He S, Li Y, Li Y
Frontiers in pharmacology 2020;11:1262
Frontiers in pharmacology 2020;11:1262
The Protective Effect of Luteolin in Glucocorticoid-Induced Osteonecrosis of the Femoral Head.
Yan Z, Zhan J, Qi W, Lin J, Huang Y, Xue X, Pan X
Frontiers in pharmacology 2020;11:1195
Frontiers in pharmacology 2020;11:1195
Gallic Acid Attenuates Angiotensin II-Induced Hypertension and Vascular Dysfunction by Inhibiting the Degradation of Endothelial Nitric Oxide Synthase.
Yan X, Zhang QY, Zhang YL, Han X, Guo SB, Li HH
Frontiers in pharmacology 2020;11:1121
Frontiers in pharmacology 2020;11:1121
Metformin Mitigates Cartilage Degradation by Activating AMPK/SIRT1-Mediated Autophagy in a Mouse Osteoarthritis Model.
Wang C, Yao Z, Zhang Y, Yang Y, Liu J, Shi Y, Zhang C
Frontiers in pharmacology 2020;11:1114
Frontiers in pharmacology 2020;11:1114
AKT Inhibitor SC66 Inhibits Proliferation and Induces Apoptosis in Human Glioblastoma Through Down-Regulating AKT/β-Catenin Pathway.
Gao L, Liu J, Xu P, Deng G, Liu B, Yuan F, Tan Y, Sun Q, Xu Y, Zhang H, Qi Y, Han S, Yang K, Geng R, Jiang H, Chen Q
Frontiers in pharmacology 2020;11:1102
Frontiers in pharmacology 2020;11:1102
De novo Synthesis of SAA1 in the Placenta Participates in Parturition.
Gan XW, Wang WS, Lu JW, Ling LJ, Zhou Q, Zhang HJ, Ying H, Sun K
Frontiers in immunology 2020;11:1038
Frontiers in immunology 2020;11:1038
MiR-185-5p Protects Against Angiogenesis in Polycystic Ovary Syndrome by Targeting VEGFA.
Wei J, Zhao Y
Frontiers in pharmacology 2020;11:1030
Frontiers in pharmacology 2020;11:1030
Inhibition of JNK-Mediated Autophagy Promotes Proscillaridin A- Induced Apoptosis via ROS Generation, Intracellular Ca(+2) Oscillation and Inhibiting STAT3 Signaling in Breast Cancer Cells.
Saleem MZ, Alshwmi M, Zhang H, Din SRU, Nisar MA, Khan M, Alam S, Alam G, Jin L, Ma T
Frontiers in pharmacology 2020;11:01055
Frontiers in pharmacology 2020;11:01055
PAQR4 promotes chemoresistance in non-small cell lung cancer through inhibiting Nrf2 protein degradation.
Xu P, Jiang L, Yang Y, Wu M, Liu B, Shi Y, Shen Q, Jiang X, He Y, Cheng D, Xiong Q, Yang Z, Duan L, Lin J, Zhao S, Shi P, Yang C, Chen Y
Theranostics 2020;10(8):3767-3778
Theranostics 2020;10(8):3767-3778
CNTNAP4 deficiency in dopaminergic neurons initiates parkinsonian phenotypes.
Zhang W, Zhou M, Lu W, Gong J, Gao F, Li Y, Xu X, Lin Y, Zhang X, Ding L, Zhang Z, Li G, Chen X, Sun X, Zhu X, Xu P, Zhang Y
Theranostics 2020;10(7):3000-3021
Theranostics 2020;10(7):3000-3021
SMYD2 suppresses APC2 expression to activate the Wnt/β-catenin pathway and promotes epithelial-mesenchymal transition in colorectal cancer.
Meng F, Liu X, Lin C, Xu L, Liu J, Zhang P, Zhang X, Song J, Yan Y, Ren Z, Zhang Y
American journal of cancer research 2020;10(3):997-1011
American journal of cancer research 2020;10(3):997-1011
Fasudil Promotes α-Synuclein Clearance in an AAV-Mediated α-Synuclein Rat Model of Parkinson's Disease by Autophagy Activation.
Yang YJ, Bu LL, Shen C, Ge JJ, He SJ, Yu HL, Tang YL, Jue Z, Sun YM, Yu WB, Zuo CT, Wu JJ, Wang J, Liu FT
Journal of Parkinson's disease 2020;10(3):969-979
Journal of Parkinson's disease 2020;10(3):969-979
Denervation drives skeletal muscle atrophy and induces mitochondrial dysfunction, mitophagy and apoptosis via miR-142a-5p/MFN1 axis.
Yang X, Xue P, Chen H, Yuan M, Kang Y, Duscher D, Machens HG, Chen Z
Theranostics 2020;10(3):1415-1432
Theranostics 2020;10(3):1415-1432
Promotion of mitochondrial fusion protects against developmental PBDE-47 neurotoxicity by restoring mitochondrial homeostasis and suppressing excessive apoptosis.
Dong L, Li P, Yang K, Liu L, Gao H, Zhou G, Zhao Q, Xia T, Wang A, Zhang S
Theranostics 2020;10(3):1245-1261
Theranostics 2020;10(3):1245-1261
Virus-induced p38 MAPK activation facilitates viral infection.
Cheng Y, Sun F, Wang L, Gao M, Xie Y, Sun Y, Liu H, Yuan Y, Yi W, Huang Z, Yan H, Peng K, Wu Y, Cao Z
Theranostics 2020;10(26):12223-12240
Theranostics 2020;10(26):12223-12240
Restoring the epigenetically silenced PCK2 suppresses renal cell carcinoma progression and increases sensitivity to sunitinib by promoting endoplasmic reticulum stress.
Xiong Z, Yuan C, Shi J, Xiong W, Huang Y, Xiao W, Yang H, Chen K, Zhang X
Theranostics 2020;10(25):11444-11461
Theranostics 2020;10(25):11444-11461
TSTA3 facilitates esophageal squamous cell carcinoma progression through regulating fucosylation of LAMP2 and ERBB2.
Zhang L, Gao Y, Zhang X, Guo M, Yang J, Cui H, Kong P, Niu X, Bi Y, Xu J, Yan T, Ma Y, Yang J, Qian Y, Wang F, Li H, Liu F, Cheng X, Cui Y
Theranostics 2020;10(24):11339-11358
Theranostics 2020;10(24):11339-11358
Truncated HDAC9 identified by integrated genome-wide screen as the key modulator for paclitaxel resistance in triple-negative breast cancer.
Lian B, Pei YC, Jiang YZ, Xue MZ, Li DQ, Li XG, Zheng YZ, Liu XY, Qiao F, Sun WL, Ling H, He M, Yao L, Hu X, Shao ZM
Theranostics 2020;10(24):11092-11109
Theranostics 2020;10(24):11092-11109
Hypergastrinemia Expands Gastric ECL Cells Through CCK2R(+) Progenitor Cells via ERK Activation.
Sheng W, Malagola E, Nienhüser H, Zhang Z, Kim W, Zamechek L, Sepulveda A, Hata M, Hayakawa Y, Zhao CM, Chen D, Wang TC
Cellular and molecular gastroenterology and hepatology 2020;10(2):434-449.e1
Cellular and molecular gastroenterology and hepatology 2020;10(2):434-449.e1
LncRNA CSMD1-1 promotes the progression of Hepatocellular Carcinoma by activating MYC signaling.
Liu J, Xu R, Mai SJ, Ma YS, Zhang MY, Cao PS, Weng NQ, Wang RQ, Cao D, Wei W, Guo RP, Zhang YJ, Xu L, Chen MS, Zhang HZ, Huang L, Fu D, Wang HY
Theranostics 2020;10(17):7527-7544
Theranostics 2020;10(17):7527-7544
Protein acetylation derepresses Serotonin Synthesis to potentiate Pancreatic Beta-Cell Function through HDAC1-PKA-Tph1 signaling.
Zhang Y, Wang S, Zhang L, Zhou F, Zhu K, Zhu Q, Liu Q, Liu Y, Jiang L, Ning G, Bi Y, Zhou L, Wang X
Theranostics 2020;10(16):7351-7368
Theranostics 2020;10(16):7351-7368
Diethyldithiocarbamate-copper nanocomplex reinforces disulfiram chemotherapeutic efficacy through light-triggered nuclear targeting.
Ren L, Feng W, Shao J, Ma J, Xu M, Zhu BZ, Zheng N, Liu S
Theranostics 2020;10(14):6384-6398
Theranostics 2020;10(14):6384-6398
Selective targeting of the oncogenic KRAS G12S mutant allele by CRISPR/Cas9 induces efficient tumor regression.
Gao Q, Ouyang W, Kang B, Han X, Xiong Y, Ding R, Li Y, Wang F, Huang L, Chen L, Wang D, Dong X, Zhang Z, Li Y, Ze B, Hou Y, Yang H, Ma Y, Gu Y, Chao CC
Theranostics 2020;10(11):5137-5153
Theranostics 2020;10(11):5137-5153
Circ-EEF2 facilitated autophagy via interaction with mir-6881-3p and ANXA2 in EOC.
Yong M, Hu J, Zhu H, Jiang X, Gan X, Hu L
American journal of cancer research 2020;10(11):3737-3751
American journal of cancer research 2020;10(11):3737-3751
LncRNA NEAT1 facilitates pancreatic cancer growth and metastasis through stabilizing ELF3 mRNA.
Feng Y, Gao L, Cui G, Cao Y
American journal of cancer research 2020;10(1):237-248
American journal of cancer research 2020;10(1):237-248
Ovary Proteome Analysis Reveals RH36 Regulates Reproduction via Vitellin Uptake Mediated by HSP70 Protein in Hard Ticks.
Wang F, Wang Y, Wang G, Zhang H, Kuang C, Zhou Y, Cao J, Zhou J
Frontiers in cellular and infection microbiology 2020;10:93
Frontiers in cellular and infection microbiology 2020;10:93
KLF13 suppresses the proliferation and growth of colorectal cancer cells through transcriptionally inhibiting HMGCS1-mediated cholesterol biosynthesis.
Yao W, Jiao Y, Zhou Y, Luo X
Cell & bioscience 2020;10:76
Cell & bioscience 2020;10:76
RAC1 Involves in the Radioresistance by Mediating Epithelial-Mesenchymal Transition in Lung Cancer.
Tan S, Yi P, Wang H, Xia L, Han Y, Wang H, Zeng B, Tang L, Pan Q, Tian Y, Rao S, Oyang L, Liang J, Lin J, Su M, Shi Y, Liao Q, Zhou Y
Frontiers in oncology 2020;10:649
Frontiers in oncology 2020;10:649
Long Noncoding RNA UCA1 Is Related to Autophagy and Apoptosis in Endometrial Stromal Cells.
Jiang L, Wan Y, Feng Z, Liu D, Ouyang L, Li Y, Liu K
Frontiers in oncology 2020;10:618472
Frontiers in oncology 2020;10:618472
circ_NOTCH3 Functions as a Protooncogene Competing With miR-205-5p, Modulating KLF12 Expression and Promoting the Development and Progression of Basal-Like Breast Carcinoma.
Guan B, Li Q, Zhang HZ, Yang HS
Frontiers in oncology 2020;10:602694
Frontiers in oncology 2020;10:602694
MLK3 Is Associated With Poor Prognosis in Patients With Glioblastomas and Actin Cytoskeleton Remodeling in Glioblastoma Cells.
Zhu Y, Sun JM, Sun ZC, Chen FJ, Wu YP, Hou XY
Frontiers in oncology 2020;10:600762
Frontiers in oncology 2020;10:600762
Antioxidant Effect of Propofol in Gliomas and Its Association With Divalent Metal Transporter 1.
Yang C, Xia Z, Li T, Chen Y, Zhao M, Sun Y, Ma J, Wu Y, Wang X, Wang P, Wang H
Frontiers in oncology 2020;10:590931
Frontiers in oncology 2020;10:590931
Characterization of ROS Metabolic Equilibrium Reclassifies Pan-Cancer Samples and Guides Pathway Targeting Therapy.
Shen S, Yan Z, Wu J, Liu X, Guan G, Zou C, Guo Q, Zhu C, Liu T, Chen C, Chen L, Cheng P, Cheng W, Wu A
Frontiers in oncology 2020;10:581197
Frontiers in oncology 2020;10:581197
Long Non-Coding RNA LINC02747 Promotes the Proliferation of Clear Cell Renal Cell Carcinoma by Inhibiting miR-608 and Activating TFE3.
Ju X, Sun Y, Zhang F, Wei X, Wang Z, He X
Frontiers in oncology 2020;10:573789
Frontiers in oncology 2020;10:573789
PUF60/AURKA Axis Contributes to Tumor Progression and Malignant Phenotypes in Bladder Cancer.
Long Q, An X, Chen M, Wang N, Sui S, Li Y, Zhang C, Lee K, Wang X, Tian T, Pan Y, Qiu H, Xie F, Deng W, Zheng F, He L
Frontiers in oncology 2020;10:568015
Frontiers in oncology 2020;10:568015
Vitamin D3 Inhibits Helicobacter pylori Infection by Activating the VitD3/VDR-CAMP Pathway in Mice.
Zhou A, Li L, Zhao G, Min L, Liu S, Zhu S, Guo Q, Liu C, Zhang S, Li P
Frontiers in cellular and infection microbiology 2020;10:566730
Frontiers in cellular and infection microbiology 2020;10:566730
Single-Cell Sequencing of Glioblastoma Reveals Central Nervous System Susceptibility to SARS-CoV-2.
Wu B, Wang W, Wang H, Zou Q, Hu B, Ye L, Hu Y, Xie Y, Huang N, Lan Q, Cheng H, Dong J, Dai X
Frontiers in oncology 2020;10:566599
Frontiers in oncology 2020;10:566599
BYSL Promotes Glioblastoma Cell Migration, Invasion, and Mesenchymal Transition Through the GSK-3β/β-Catenin Signaling Pathway.
Sha Z, Zhou J, Wu Y, Zhang T, Li C, Meng Q, Musunuru PP, You F, Wu Y, Yu R, Gao S
Frontiers in oncology 2020;10:565225
Frontiers in oncology 2020;10:565225
TDO2 Promotes the EMT of Hepatocellular Carcinoma Through Kyn-AhR Pathway.
Li L, Wang T, Li S, Chen Z, Wu J, Cao W, Wo Q, Qin X, Xu J
Frontiers in oncology 2020;10:562823
Frontiers in oncology 2020;10:562823
Carbohydrate Sulfotransferase 4 Inhibits the Progression of Hepatitis B Virus-Related Hepatocellular Carcinoma and Is a Potential Prognostic Marker in Several Tumors.
Zhang L, Fan Y, Wang X, Yang M, Wu X, Huang W, Lan J, Liao L, Huang W, Yuan L, Pan H, Wu Y, Chen L, Guan J
Frontiers in oncology 2020;10:554331
Frontiers in oncology 2020;10:554331
FOXK1 Promotes Proliferation and Metastasis of Gallbladder Cancer by Activating AKT/mTOR Signaling Pathway.
Wencong M, Jinghan W, Yong Y, Jianyang A, Bin L, Qingbao C, Chen L, Xiaoqing J
Frontiers in oncology 2020;10:545
Frontiers in oncology 2020;10:545
Thioguanine Induces Apoptosis in Triple-Negative Breast Cancer by Regulating PI3K-AKT Pathway.
Zhang D, An X, Li Q, Man X, Chu M, Li H, Zhang N, Dai X, Yu H, Li Z
Frontiers in oncology 2020;10:524922
Frontiers in oncology 2020;10:524922
Long Non-coding RNA CCAT1 Acts as an Oncogene and Promotes Sunitinib Resistance in Renal Cell Carcinoma.
Shan L, Liu W, Zhan Y
Frontiers in oncology 2020;10:516552
Frontiers in oncology 2020;10:516552
CDC27 Promotes Tumor Progression and Affects PD-L1 Expression in T-Cell Lymphoblastic Lymphoma.
Song Y, Song W, Li Z, Song W, Wen Y, Li J, Xia Q, Zhang M
Frontiers in oncology 2020;10:488
Frontiers in oncology 2020;10:488
Nicotine Reduces Human Brain Microvascular Endothelial Cell Response to Escherichia coli K1 Infection by Inhibiting Autophagy.
Wu C, Yang M, Liu R, Hu H, Ji L, Zhang X, Huang S, Wang L
Frontiers in cellular and infection microbiology 2020;10:484
Frontiers in cellular and infection microbiology 2020;10:484
Nevirapine Increases Sodium/Iodide Symporter-Mediated Radioiodide Uptake by Activation of TSHR/cAMP/CREB/PAX8 Signaling Pathway in Dedifferentiated Thyroid Cancer.
Shang H, Zhao J, Yao J, Wang H, Dong J, Liao L
Frontiers in oncology 2020;10:404
Frontiers in oncology 2020;10:404
EGFR/FOXO3A/LXR-α Axis Promotes Prostate Cancer Proliferation and Metastasis and Dual-Targeting LXR-α/EGFR Shows Synthetic Lethality.
Chen T, Xu J, Fu W
Frontiers in oncology 2020;10:1688
Frontiers in oncology 2020;10:1688
miR-15b-5p Promotes Growth and Metastasis in Breast Cancer by Targeting HPSE2.
Wu B, Liu G, Jin Y, Yang T, Zhang D, Ding L, Zhou F, Pan Y, Wei Y
Frontiers in oncology 2020;10:108
Frontiers in oncology 2020;10:108
Conditional ablation of MAPK7 expression in chondrocytes impairs endochondral bone formation in limbs and adaptation of chondrocytes to hypoxia.
Yang X, Zhong D, Gao W, Liao Z, Chen Y, Zhang S, Zhou H, Su P, Xu C
Cell & bioscience 2020;10:103
Cell & bioscience 2020;10:103
The neuro-immune interaction in airway inflammation through TRPA1 expression in CD4+ T cells of asthmatic mice.
Li M, Fan X, Yue Q, Hu F, Zhang Y, Zhu C
International immunopharmacology 2020 Sep;86:106696
International immunopharmacology 2020 Sep;86:106696
Curcumin ameliorates CKD-induced mitochondrial dysfunction and oxidative stress through inhibiting GSK-3β activity.
Wang D, Yang Y, Zou X, Zheng Z, Zhang J
The Journal of nutritional biochemistry 2020 Sep;83:108404
The Journal of nutritional biochemistry 2020 Sep;83:108404
Resveratrol inhibits the tumor migration and invasion by upregulating TET1 and reducing TIMP2/3 methylation in prostate carcinoma cells.
Wang K, Chen Z, Shi J, Feng Y, Yu M, Sun Y, Zhuang Q, Liang B, Luo G, Xu X, Fan M
The Prostate 2020 Sep;80(12):977-985
The Prostate 2020 Sep;80(12):977-985
METTL7B (methyltransferase-like 7B) identification as a novel biomarker for lung adenocarcinoma.
Ali J, Liu W, Duan W, Liu C, Song J, Ali S, Li E, Wang Q
Annals of translational medicine 2020 Sep;8(18):1130
Annals of translational medicine 2020 Sep;8(18):1130
Magnolol inhibits myotube atrophy induced by cancer cachexia through myostatin signaling pathway in vitro.
Ge Z, Liu D, Shang Y, Li Y, Chen SZ
Journal of natural medicines 2020 Sep;74(4):741-749
Journal of natural medicines 2020 Sep;74(4):741-749
Bisphenol-A exposure induced neurotoxicity and associated with synapse and cytoskeleton in Neuro-2a cells.
Yin Z, Hua L, Chen L, Hu D, Li J, An Z, Tian T, Ning H, Ge Y
Toxicology in vitro : an international journal published in association with BIBRA 2020 Sep;67:104911
Toxicology in vitro : an international journal published in association with BIBRA 2020 Sep;67:104911
Islet-cell autoantigen 69 accelerates liver regeneration by downregulating Tgfbr1 and attenuating Tgfβ signaling in mice.
Chen L, Tao F, Zhang Y, Shu C, Xiang W, Yang L, Chen X, Hong Y, Chen B, Li K, Zhang W, Hao K, Ge F, Wang Z, Lyu J
FEBS letters 2020 Sep;594(17):2881-2893
FEBS letters 2020 Sep;594(17):2881-2893
GBP1 promotes erlotinib resistance via PGK1‑activated EMT signaling in non‑small cell lung cancer.
Cheng L, Gou L, Wei T, Zhang J
International journal of oncology 2020 Sep;57(3):858-870
International journal of oncology 2020 Sep;57(3):858-870
ID1 overexpression promotes HCC progression by amplifying the AURKA/Myc signaling pathway.
Wu M, Zhou Y, Fei C, Chen T, Yin X, Zhang L, Ren Z
International journal of oncology 2020 Sep;57(3):845-857
International journal of oncology 2020 Sep;57(3):845-857
Protein phosphorylation profiling of peripheral nerve regeneration after autologous nerve grafting.
Cheng Z, Shen Y, Qian T, Yi S, He J
Molecular and cellular biochemistry 2020 Sep;472(1-2):35-44
Molecular and cellular biochemistry 2020 Sep;472(1-2):35-44
High glucose condition inhibits trophoblast proliferation, migration and invasion by downregulating placental growth factor expression.
Tao J, Xia LZ, Chen JJ, Zeng JF, Meng J, Wu S, Wang Z
The journal of obstetrics and gynaecology research 2020 Sep;46(9):1690-1701
The journal of obstetrics and gynaecology research 2020 Sep;46(9):1690-1701
Sodium Butyrate Exacerbates Parkinson's Disease by Aggravating Neuroinflammation and Colonic Inflammation in MPTP-Induced Mice Model.
Qiao CM, Sun MF, Jia XB, Li Y, Zhang BP, Zhao LP, Shi Y, Zhou ZL, Zhu YL, Cui C, Shen YQ
Neurochemical research 2020 Sep;45(9):2128-2142
Neurochemical research 2020 Sep;45(9):2128-2142
A Novel Compound YS-5-23 Exhibits Neuroprotective Effect by Reducing β-Site Amyloid Precursor Protein Cleaving Enzyme 1's Expression and H(2)O(2)-Induced Cytotoxicity in SH-SY5Y Cells.
Cheng C, Zheng N, Sun D, Fang W, Zheng L, Song W, Huang J
Neurochemical research 2020 Sep;45(9):2113-2127
Neurochemical research 2020 Sep;45(9):2113-2127
ErbB4 knockdown in serotonergic neurons in the dorsal raphe induces anxiety-like behaviors.
Zhang SR, Wu JL, Chen H, Luo R, Chen WJ, Tang LJ, Li XW, Yang JM, Gao TM
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2020 Sep;45(10):1698-1706
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2020 Sep;45(10):1698-1706
Differential regulation of Actn2 and Actn3 expression during unfolded protein response in C2C12 myotubes.
Harada N, Gotoda Y, Hatakeyama A, Nakagawa T, Miyatake Y, Kuroda M, Masumoto S, Tsutsumi R, Nakaya Y, Sakaue H
Journal of muscle research and cell motility 2020 Sep;41(2-3):199-209
Journal of muscle research and cell motility 2020 Sep;41(2-3):199-209
Mitochondrial superoxide contributes to oxidative stress exacerbated by DNA damage response in RAD51-depleted ovarian cancer cells.
Xu L, Wu T, Lu S, Hao X, Qin J, Wang J, Zhang X, Liu Q, Kong B, Gong Y, Liu Z, Shao C
Redox biology 2020 Sep;36:101604
Redox biology 2020 Sep;36:101604
Obesity promotes gastric cancer metastasis via diacylglycerol acyltransferase 2-dependent lipid droplets accumulation and redox homeostasis.
Li S, Wu T, Lu YX, Wang JX, Yu FH, Yang MZ, Huang YJ, Li ZJ, Wang SL, Huang L, Lu L, Tian T
Redox biology 2020 Sep;36:101596
Redox biology 2020 Sep;36:101596
Quercetin alleviated H(2) O(2) -induced apoptosis and steroidogenic impairment in goat luteinized granulosa cells.
Li M, Xue Y, Yu H, Mao D
Journal of biochemical and molecular toxicology 2020 Sep;34(9):e22527
Journal of biochemical and molecular toxicology 2020 Sep;34(9):e22527
Vagus Nerve Stimulation Attenuates Early Traumatic Brain Injury by Regulating the NF-κB/NLRP3 Signaling Pathway.
Tang Y, Dong X, Chen G, Ye W, Kang J, Tang Y, Feng Z
Neurorehabilitation and neural repair 2020 Sep;34(9):831-843
Neurorehabilitation and neural repair 2020 Sep;34(9):831-843
APC2(CDH1) negatively regulates agrin signaling by promoting the ubiquitination and proteolytic degradation of DOK7.
Chen A, Bai L, Zhong K, Shu X, Wang A, Xiao Y, Zhang K, Shen C
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Sep;34(9):12009-12023
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Sep;34(9):12009-12023
Selenoprotein T protects against cisplatin-induced acute kidney injury through suppression of oxidative stress and apoptosis.
Huang J, Bao D, Lei CT, Tang H, Zhang CY, Su H, Zhang C
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Sep;34(9):11983-11996
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Sep;34(9):11983-11996
The MAF1 Phosphoregulatory Region Controls MAF1 Interaction with the RNA Polymerase III C34 Subunit and Transcriptional Repression in Plants.
Oliveira Andrade M, Sforça ML, Batista FAH, Figueira ACM, Benedetti CE
The Plant cell 2020 Sep;32(9):3019-3035
The Plant cell 2020 Sep;32(9):3019-3035
A paralog-specific role of COPI vesicles in the neuronal differentiation of mouse pluripotent cells.
Jain Goyal M, Zhao X, Bozhinova M, Andrade-López K, de Heus C, Schulze-Dramac S, Müller-McNicoll M, Klumperman J, Béthune J
Life science alliance 2020 Sep;3(9)
Life science alliance 2020 Sep;3(9)
The deubiquitylase USP2 maintains ErbB2 abundance via counteracting endocytic degradation and represents a therapeutic target in ErbB2-positive breast cancer.
Zhang J, Liu S, Li Q, Shi Y, Wu Y, Liu F, Wang S, Zaky MY, Yousuf W, Sun Q, Guo D, Wang T, Zhang Y, Wang Y, Li M, Liu H
Cell death and differentiation 2020 Sep;27(9):2710-2725
Cell death and differentiation 2020 Sep;27(9):2710-2725
Cardioprotection by isosteviol derivate JC105: A unique drug property to activate ERK1/2 only when cells are exposed to hypoxia-reoxygenation.
Mohammed Abdul KS, Rayadurgam J, Faiz N, Jovanović A, Tan W
Journal of cellular and molecular medicine 2020 Sep;24(18):10924-10934
Journal of cellular and molecular medicine 2020 Sep;24(18):10924-10934
Decreased ANGPTL4 impairs endometrial angiogenesis during peri-implantation period in patients with recurrent implantation failure.
Li M, Hu J, Yao L, Gao M
Journal of cellular and molecular medicine 2020 Sep;24(18):10730-10743
Journal of cellular and molecular medicine 2020 Sep;24(18):10730-10743
Follicle-stimulating hormone impairs dental pulp stem cells odontogenic differentiation.
Qian H, Guan X
Journal of cellular and molecular medicine 2020 Sep;24(18):10621-10635
Journal of cellular and molecular medicine 2020 Sep;24(18):10621-10635
Musashi2 promotes the progression of pancreatic cancer through a novel ISYNA1-p21/ZEB-1 pathway.
Zhou L, Sheng W, Jia C, Shi X, Cao R, Wang G, Lin Y, Zhu F, Dong Q, Dong M
Journal of cellular and molecular medicine 2020 Sep;24(18):10560-10572
Journal of cellular and molecular medicine 2020 Sep;24(18):10560-10572
AKR1C2 acts as a targetable oncogene in esophageal squamous cell carcinoma via activating PI3K/AKT signaling pathway.
Zhang ZF, Huang TJ, Zhang XK, Xie YJ, Lin ST, Luo FF, Meng DF, Hu H, Wang J, Peng LX, Qian CN, Cheng C, Huang BJ
Journal of cellular and molecular medicine 2020 Sep;24(17):9999-10012
Journal of cellular and molecular medicine 2020 Sep;24(17):9999-10012
Aberrant ASPM expression mediated by transcriptional regulation of FoxM1 promotes the progression of gliomas.
Zeng WJ, Cheng Q, Wen ZP, Wang JY, Chen YH, Zhao J, Gong ZC, Chen XP
Journal of cellular and molecular medicine 2020 Sep;24(17):9613-9626
Journal of cellular and molecular medicine 2020 Sep;24(17):9613-9626
UVA influenced the SIRT1-miR-27a-5p-SMAD2-MMP1/COL1/BCL2 axis in human skin primary fibroblasts.
Jiang SB, Lu YS, Liu T, Li LM, Wang HX, Wu Y, Gao XH, Chen HD
Journal of cellular and molecular medicine 2020 Sep;24(17):10027-10041
Journal of cellular and molecular medicine 2020 Sep;24(17):10027-10041
Deubiquitinase USP13 promotes extracellular matrix expression by stabilizing Smad4 in lung fibroblast cells.
Liao X, Li Y, Liu J, Zhang Y, Tan J, Kass DJ, Rojas M, Mallampalli RK, Zhao J, Zhao Y
Translational research : the journal of laboratory and clinical medicine 2020 Sep;223:15-24
Translational research : the journal of laboratory and clinical medicine 2020 Sep;223:15-24
TRIM11 promotes breast cancer cell proliferation by stabilizing estrogen receptor α.
Tang J, Luo Y, Tian Z, Liao X, Cui Q, Yang Q, Wu G
Neoplasia (New York, N.Y.) 2020 Sep;22(9):343-351
Neoplasia (New York, N.Y.) 2020 Sep;22(9):343-351
Circular RNA hsa_circ_0005556 Accelerates Gastric Cancer Progression by Sponging miR-4270 to Increase MMP19 Expression.
Shen D, Zhao H, Zeng P, Song J, Yang Y, Gu X, Ji Q, Zhao W
Journal of gastric cancer 2020 Sep;20(3):300-312
Journal of gastric cancer 2020 Sep;20(3):300-312
Antiviral immune mechanism of Toll-like receptor 4-mediated human alveolar epithelial cells type Ⅱ.
Wang D, Wang J
Experimental and therapeutic medicine 2020 Sep;20(3):2561-2568
Experimental and therapeutic medicine 2020 Sep;20(3):2561-2568
Oxidation of multiple MiT/TFE transcription factors links oxidative stress to transcriptional control of autophagy and lysosome biogenesis.
Wang H, Wang N, Xu D, Ma Q, Chen Y, Xu S, Xia Q, Zhang Y, Prehn JHM, Wang G, Ying Z
Autophagy 2020 Sep;16(9):1683-1696
Autophagy 2020 Sep;16(9):1683-1696
Myeloid Cell Expression of LACC1 Is Required for Bacterial Clearance and Control of Intestinal Inflammation.
Kang JW, Yan J, Ranjan K, Zhang X, Turner JR, Abraham C
Gastroenterology 2020 Sep;159(3):1051-1067
Gastroenterology 2020 Sep;159(3):1051-1067
BAIAP2L2 promotes the progression of gastric cancer via AKT/mTOR and Wnt3a/β-catenin signaling pathways.
Liu J, Shangguan Y, Sun J, Cong W, Xie Y
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Sep;129:110414
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Sep;129:110414
PM2.5 compromises antiviral immunity in influenza infection by inhibiting activation of NLRP3 inflammasome and expression of interferon-β.
Tao RJ, Cao WJ, Li MH, Yang L, Dai RX, Luo XL, Liu Y, Ge BX, Su X, Xu JF
Molecular immunology 2020 Sep;125:178-186
Molecular immunology 2020 Sep;125:178-186
Novel long non-coding RNA LINC02323 promotes epithelial-mesenchymal transition and metastasis via sponging miR-1343-3p in lung adenocarcinoma.
Zhang X, Du L, Han J, Li X, Wang H, Zheng G, Wang Y, Yang Y, Hu Y, Wang C
Thoracic cancer 2020 Sep;11(9):2506-2516
Thoracic cancer 2020 Sep;11(9):2506-2516
Icariside Ⅱ, a main compound in Epimedii Folium, induces idiosyncratic hepatotoxicity by enhancing NLRP3 inflammasome activation.
Wang Z, Xu G, Wang H, Zhan X, Gao Y, Chen N, Li R, Song X, Guo Y, Yang R, Niu M, Wang J, Liu Y, Xiao X, Bai Z
Acta pharmaceutica Sinica. B 2020 Sep;10(9):1619-1633
Acta pharmaceutica Sinica. B 2020 Sep;10(9):1619-1633
Impaired NHEJ repair in amyotrophic lateral sclerosis is associated with TDP-43 mutations.
Konopka A, Whelan DR, Jamali MS, Perri E, Shahheydari H, Toth RP, Parakh S, Robinson T, Cheong A, Mehta P, Vidal M, Ragagnin AMG, Khizhnyak I, Jagaraj CJ, Galper J, Grima N, Deva A, Shadfar S, Nicholson GA, Yang S, Cutts SM, Horejsi Z, Bell TDM, Walker AK, Blair IP, Atkin JD
Molecular neurodegeneration 2020 Sep 9;15(1):51
Molecular neurodegeneration 2020 Sep 9;15(1):51
Functional regulation of an ancestral RAG transposon ProtoRAG by a trans-acting factor YY1 in lancelet.
Liu S, Yuan S, Gao X, Tao X, Yu W, Li X, Chen S, Xu A
Nature communications 2020 Sep 9;11(1):4515
Nature communications 2020 Sep 9;11(1):4515
Legionella Manipulates Non-canonical SNARE Pairing Using a Bacterial Deubiquitinase.
Kitao T, Taguchi K, Seto S, Arasaki K, Ando H, Nagai H, Kubori T
Cell reports 2020 Sep 8;32(10):108107
Cell reports 2020 Sep 8;32(10):108107
MiR-126 Regulates Properties of SOX9(+) Liver Progenitor Cells during Liver Repair by Targeting Hoxb6.
Yan Y, Wang R, Hu X, Wang S, Zhang L, Hou C, Zhang L
Stem cell reports 2020 Sep 8;15(3):706-720
Stem cell reports 2020 Sep 8;15(3):706-720
Knockdown of TXNDC9 induces apoptosis and autophagy in glioma and mediates cell differentiation by p53 activation.
Zheng T, Chen K, Zhang X, Feng H, Shi Y, Liu L, Zhang J, Chen Y
Aging 2020 Sep 8;12(18):18649-18659
Aging 2020 Sep 8;12(18):18649-18659
Autocrine INSL5 promotes tumor progression and glycolysis via activation of STAT5 signaling.
Li SB, Liu YY, Yuan L, Ji MF, Zhang A, Li HY, Tang LQ, Fang SG, Zhang H, Xing S, Li MZ, Zhong Q, Lin SJ, Liu WL, Huang P, Zeng YX, Zheng YM, Ling ZQ, Sui JH, Zeng MS
EMBO molecular medicine 2020 Sep 7;12(9):e12050
EMBO molecular medicine 2020 Sep 7;12(9):e12050
hUMSCs regulate the differentiation of ovarian stromal cells via TGF-β(1)/Smad3 signaling pathway to inhibit ovarian fibrosis to repair ovarian function in POI rats.
Cui L, Bao H, Liu Z, Man X, Liu H, Hou Y, Luo Q, Wang S, Fu Q, Zhang H
Stem cell research & therapy 2020 Sep 7;11(1):386
Stem cell research & therapy 2020 Sep 7;11(1):386
Palmatine ameliorates Helicobacter pylori-induced chronic atrophic gastritis by inhibiting MMP-10 through ADAM17/EGFR.
Chen X, Wang R, Bao C, Zhang J, Zhang J, Li R, Wu S, Wen J, Yang T, Wei S, Li H, Wei Y, Ren S, Zhao Y
European journal of pharmacology 2020 Sep 5;882:173267
European journal of pharmacology 2020 Sep 5;882:173267
Long non-coding RNA FAM133B-2 represses the radio-resistance of nasopharyngeal cancer cells by targeting miR-34a-5p/CDK6 axis.
Huang D, Zhu X, Wang Y, Yu H, Pu Y
Aging 2020 Sep 5;12(17):16936-16950
Aging 2020 Sep 5;12(17):16936-16950
Neuroprotective Effect of Piracetam against Cocaine-Induced Neuro Epigenetic Modification of DNA Methylation in Astrocytes.
Sivalingam K, Samikkannu T
Brain sciences 2020 Sep 5;10(9)
Brain sciences 2020 Sep 5;10(9)
YAP1 Inhibition in HUVECs Is Associated with Released Exosomes and Increased Hepatocarcinoma Invasion and Metastasis.
Li Y, Zhang X, Zheng Q, Zhang Y, Ma Y, Zhu C, Yang L, Peng X, Wang Q, Wang B, Meng X, Li H, Liu J
Molecular therapy. Nucleic acids 2020 Sep 4;21:86-97
Molecular therapy. Nucleic acids 2020 Sep 4;21:86-97
Circular RNA circREPS2 Acts as a Sponge of miR-558 to Suppress Gastric Cancer Progression by Regulating RUNX3/β-catenin Signaling.
Guo X, Dai X, Liu J, Cheng A, Qin C, Wang Z
Molecular therapy. Nucleic acids 2020 Sep 4;21:577-591
Molecular therapy. Nucleic acids 2020 Sep 4;21:577-591
Fc-Elabela fusion protein attenuates lipopolysaccharide-induced kidney injury in mice.
Xu F, Zhou H, Wu M, Zhang H, Zhang Y, Zhao Q, Brown R, Gong DW, Miao L
Bioscience reports 2020 Sep 30;40(9)
Bioscience reports 2020 Sep 30;40(9)
Porphyromonas gingivalis disrupts vascular endothelial homeostasis in a TLR-NF-κB axis dependent manner.
Xie M, Tang Q, Yu S, Sun J, Mei F, Zhao J, Chen L
International journal of oral science 2020 Sep 30;12(1):28
International journal of oral science 2020 Sep 30;12(1):28
Anti-bacterial and anti-viral nanchangmycin displays anti-myeloma activity by targeting Otub1 and c-Maf.
Xu Y, Sun T, Zeng K, Xu M, Chen J, Xu X, Zhang Z, Cao B, Tang X, Wu D, Kong Y, Zeng Y, Mao X
Cell death & disease 2020 Sep 30;11(9):818
Cell death & disease 2020 Sep 30;11(9):818
Quality Control of ER Membrane Proteins by the RNF185/Membralin Ubiquitin Ligase Complex.
van de Weijer ML, Krshnan L, Liberatori S, Guerrero EN, Robson-Tull J, Hahn L, Lebbink RJ, Wiertz EJHJ, Fischer R, Ebner D, Carvalho P
Molecular cell 2020 Sep 3;79(5):768-781.e7
Molecular cell 2020 Sep 3;79(5):768-781.e7
Aldehyde dehydrogenase 2 inhibited oxidized LDL-induced NLRP3 inflammasome priming and activation via attenuating oxidative stress.
Xu Y, Yuan Q, Cao S, Cui S, Xue L, Song X, Li Z, Xu R, Yuan Q, Li R
Biochemical and biophysical research communications 2020 Sep 3;529(4):998-1004
Biochemical and biophysical research communications 2020 Sep 3;529(4):998-1004
KLF16 overexpression deleteriously affects the proliferation and migration of retinoblastoma by transcriptionally repressing BCL2L15.
Zhang JX, Yan XJ, Wu S, Liu Q, Ma JM
Biochemical and biophysical research communications 2020 Sep 3;529(4):977-983
Biochemical and biophysical research communications 2020 Sep 3;529(4):977-983
BAP1 regulates AMPK-mTOR signalling pathway through deubiquitinating and stabilizing tumour-suppressor LKB1.
Yang C, Ding H, Yang Y, Yang L, Yang Y, Fang M, Ren J, Hu R, Wang C, Geng W
Biochemical and biophysical research communications 2020 Sep 3;529(4):1025-1032
Biochemical and biophysical research communications 2020 Sep 3;529(4):1025-1032
The microRNA/TET3/REST axis is required for olfactory globose basal cell proliferation and male behavior.
Yang D, Wu X, Zhou Y, Wang W, Wang Z
EMBO reports 2020 Sep 3;21(9):e49431
EMBO reports 2020 Sep 3;21(9):e49431
TRIM29 inhibits miR-873-5P biogenesis via CYTOR to upregulate fibronectin 1 and promotes invasion of papillary thyroid cancer cells.
Wu T, Zhang DL, Wang JM, Jiang JY, Du X, Zeng XY, Du ZX
Cell death & disease 2020 Sep 29;11(9):813
Cell death & disease 2020 Sep 29;11(9):813
Maternal sevoflurane exposure affects differentiation of hippocampal neural stem cells by regulating miR-410-3p and ATN1.
Zhang Y, Wu Z, Li X, Wan Y, Zhang Y, Zhao P
Stem cell research & therapy 2020 Sep 29;11(1):423
Stem cell research & therapy 2020 Sep 29;11(1):423
Antimicrobial Effect of Zophobas morio Hemolymph against Bovine Mastitis Pathogens.
Du M, Liu X, Xu J, Li S, Wang S, Zhu Y, Wang J
Microorganisms 2020 Sep 28;8(10)
Microorganisms 2020 Sep 28;8(10)
Establishment and characterization of a PCOS and a normal human granulosa cell line.
Hashemian Z, Afsharian P, Farzaneh P, Eftekhari-Yazdi P, Vakhshiteh F, Daneshvar Amoli A, Nasimian A
Cytotechnology 2020 Sep 28;72(6):833-45
Cytotechnology 2020 Sep 28;72(6):833-45
Small-molecule MMP2/MMP9 inhibitor SB-3CT modulates tumor immune surveillance by regulating PD-L1.
Ye Y, Kuang X, Xie Z, Liang L, Zhang Z, Zhang Y, Ma F, Gao Q, Chang R, Lee HH, Zhao S, Su J, Li H, Peng J, Chen H, Yin M, Peng C, Yang N, Wang J, Liu J, Liu H, Han L, Chen X
Genome medicine 2020 Sep 28;12(1):83
Genome medicine 2020 Sep 28;12(1):83
Multi-Compartment, Early Disruption of cGMP and cAMP Signalling in Cardiac Myocytes from the mdx Model of Duchenne Muscular Dystrophy.
Brescia M, Chao YC, Koschinski A, Tomek J, Zaccolo M
International journal of molecular sciences 2020 Sep 25;21(19)
International journal of molecular sciences 2020 Sep 25;21(19)
Imaging-Based Reporter Systems to Define CVB-Induced Membrane Remodeling in Living Cells.
Lennemann NJ, Evans AS, Coyne CB
Viruses 2020 Sep 25;12(10)
Viruses 2020 Sep 25;12(10)
RNA-binding protein CUGBP1 controls the differential INSR splicing in molecular subtypes of breast cancer cells and affects cell aggressiveness.
Huang G, Song C, Wang N, Qin T, Sui S, Obr A, Zeng L, Wood TL, Leroith D, Li M, Wu Y
Carcinogenesis 2020 Sep 24;41(9):1294-1305
Carcinogenesis 2020 Sep 24;41(9):1294-1305
MSC-derived exosomes promote recovery from traumatic brain injury via microglia/macrophages in rat.
Chen Y, Li J, Ma B, Li N, Wang S, Sun Z, Xue C, Han Q, Wei J, Zhao RC
Aging 2020 Sep 23;12(18):18274-18296
Aging 2020 Sep 23;12(18):18274-18296
Peptidome analysis of umbilical cord mesenchymal stem cell (hUC-MSC) conditioned medium from preterm and term infants.
Wang Y, Zhang L, Wu Y, Zhu R, Wang Y, Cao Y, Long W, Ji C, Wang H, You L
Stem cell research & therapy 2020 Sep 23;11(1):414
Stem cell research & therapy 2020 Sep 23;11(1):414
Bardoxolone conjugation enables targeted protein degradation of BRD4.
Tong B, Luo M, Xie Y, Spradlin JN, Tallarico JA, McKenna JM, Schirle M, Maimone TJ, Nomura DK
Scientific reports 2020 Sep 23;10(1):15543
Scientific reports 2020 Sep 23;10(1):15543
NIR-II window tracking of hyperglycemia induced intracerebral hemorrhage in cerebral cavernous malformation deficient mice.
Parchur AK, Fang Z, Jagtap JM, Sharma G, Hansen C, Shafiee S, Hu W, Miao QR, Joshi A
Biomaterials science 2020 Sep 21;8(18):5133-5144
Biomaterials science 2020 Sep 21;8(18):5133-5144
CD36 facilitates fatty acid uptake by dynamic palmitoylation-regulated endocytosis.
Hao JW, Wang J, Guo H, Zhao YY, Sun HH, Li YF, Lai XY, Zhao N, Wang X, Xie C, Hong L, Huang X, Wang HR, Li CB, Liang B, Chen S, Zhao TJ
Nature communications 2020 Sep 21;11(1):4765
Nature communications 2020 Sep 21;11(1):4765
miR-29a Modulates GSK3β/SIRT1-Linked Mitochondrial Proteostatic Stress to Ameliorate Mouse Non-Alcoholic Steatohepatitis.
Yang YL, Wang PW, Wang FS, Lin HY, Huang YH
International journal of molecular sciences 2020 Sep 19;21(18)
International journal of molecular sciences 2020 Sep 19;21(18)
NRF2 preserves genomic integrity by facilitating ATR activation and G2 cell cycle arrest.
Sun X, Wang Y, Ji K, Liu Y, Kong Y, Nie S, Li N, Hao J, Xie Y, Xu C, Du L, Liu Q
Nucleic acids research 2020 Sep 18;48(16):9109-9123
Nucleic acids research 2020 Sep 18;48(16):9109-9123
Complex I mutations synergize to worsen the phenotypic expression of Leber's hereditary optic neuropathy.
Ji Y, Zhang J, Lu Y, Yi Q, Chen M, Xie S, Mao X, Xiao Y, Meng F, Zhang M, Yang R, Guan MX
The Journal of biological chemistry 2020 Sep 18;295(38):13224-13238
The Journal of biological chemistry 2020 Sep 18;295(38):13224-13238
Zinc oxide nanoparticles effectively regulate autophagic cell death by activating autophagosome formation and interfering with their maturation.
Liu Z, Lv X, Xu L, Liu X, Zhu X, Song E, Song Y
Particle and fibre toxicology 2020 Sep 18;17(1):46
Particle and fibre toxicology 2020 Sep 18;17(1):46
Cepharanthine and Curcumin inhibited mitochondrial apoptosis induced by PCV2.
Xu Y, Zheng J, Sun P, Guo J, Zheng X, Sun Y, Fan K, Yin W, Li H, Sun N
BMC veterinary research 2020 Sep 18;16(1):345
BMC veterinary research 2020 Sep 18;16(1):345
Resveratrol alleviates the interleukin-1β-induced chondrocytes injury through the NF-κB signaling pathway.
Yi H, Zhang W, Cui ZM, Cui SY, Fan JB, Zhu XH, Liu W
Journal of orthopaedic surgery and research 2020 Sep 18;15(1):424
Journal of orthopaedic surgery and research 2020 Sep 18;15(1):424
AKT2 regulates development and metabolic homeostasis via AMPK-depedent pathway in skeletal muscle.
Chen M, Ji C, Yang Q, Gao S, Peng Y, Li Z, Gao X, Li Y, Jiang N, Zhang Y, Bian X, Chen C, Zhang K, Sanchis D, Yan F, Ye J
Clinical science (London, England : 1979) 2020 Sep 18;134(17):2381-2398
Clinical science (London, England : 1979) 2020 Sep 18;134(17):2381-2398
Cyclin G2 Is Involved in the Proliferation of Placental Trophoblast Cells and Their Interactions with Endothelial Cells.
Sun M, Liu S, Gao J, Meng T, Xing X, Chen C, Chen H, Luo Y
Medical science monitor : international medical journal of experimental and clinical research 2020 Sep 17;26:e926414
Medical science monitor : international medical journal of experimental and clinical research 2020 Sep 17;26:e926414
Stachydrine hydrochloride suppresses phenylephrine-induced pathological cardiac hypertrophy by inhibiting the calcineurin/nuclear factor of activated T-cell signalling pathway.
Zheng J, Tian J, Wang S, Hu P, Wu Q, Shan X, Zhao P, Zhang C, Guo W, Xu M, Chen H, Lu R
European journal of pharmacology 2020 Sep 15;883:173386
European journal of pharmacology 2020 Sep 15;883:173386
α-Cyperone inhibits the proliferation of human cervical cancer HeLa cells via ROS-mediated PI3K/Akt/mTOR signaling pathway.
Pei XD, Yao HL, Shen LQ, Yang Y, Lu L, Xiao JS, Wang XY, He ZL, Jiang LH
European journal of pharmacology 2020 Sep 15;883:173355
European journal of pharmacology 2020 Sep 15;883:173355
Co-inhibition of the TGF-β pathway and the PD-L1 checkpoint by pH-responsive clustered nanoparticles for pancreatic cancer microenvironment regulation and anti-tumor immunotherapy.
Wang Y, Gao Z, Du X, Chen S, Zhang W, Wang J, Li H, He X, Cao J, Wang J
Biomaterials science 2020 Sep 15;8(18):5121-5132
Biomaterials science 2020 Sep 15;8(18):5121-5132
MicroRNA-183 exerts a protective role in lupus nephritis through blunting the activation of TGF-β/Smad/TLR3 pathway via reducing Tgfbr1.
Qi H, Cao Q, Liu Q
Experimental cell research 2020 Sep 15;394(2):112138
Experimental cell research 2020 Sep 15;394(2):112138
The Natural Compound Notopterol Binds and Targets JAK2/3 to Ameliorate Inflammation and Arthritis.
Wang Q, Zhou X, Yang L, Zhao Y, Chew Z, Xiao J, Liu C, Zheng X, Zheng Y, Shi Q, Liang Q, Wang Y, Wang H
Cell reports 2020 Sep 15;32(11):108158
Cell reports 2020 Sep 15;32(11):108158
A tRNA-derived fragment (tRF-3001b) aggravates the development of nonalcoholic fatty liver disease by inhibiting autophagy.
Zhu J, Cheng M, Zhao X
Life sciences 2020 Sep 15;257:118125
Life sciences 2020 Sep 15;257:118125
Inhibition of PP2A enhances the osteogenic differentiation of human aortic valvular interstitial cells via ERK and p38 MAPK pathways.
Xie F, Li F, Li R, Liu Z, Shi J, Zhang C, Dong N
Life sciences 2020 Sep 15;257:118086
Life sciences 2020 Sep 15;257:118086
Paired box 9 regulates VSMC phenotypic transformation, proliferation, and migration via sonic hedgehog.
Xu J, Zhang Y, You S, Guo Y, Chen S, Chang Y, Zhang N, Sun Y
Life sciences 2020 Sep 15;257:118053
Life sciences 2020 Sep 15;257:118053
Melatonin rescues glucocorticoid-induced inhibition of osteoblast differentiation in MC3T3-E1 cells via the PI3K/AKT and BMP/Smad signalling pathways.
Zhao R, Tao L, Qiu S, Shen L, Tian Y, Gong Z, Tao ZB, Zhu Y
Life sciences 2020 Sep 15;257:118044
Life sciences 2020 Sep 15;257:118044
BMSC-derived exosomes alleviate smoke inhalation lung injury through blockade of the HMGB1/NF-κB pathway.
Xu B, Gan CX, Chen SS, Li JQ, Liu MZ, Guo GH
Life sciences 2020 Sep 15;257:118042
Life sciences 2020 Sep 15;257:118042
High fat diet impairs spermatogenesis by regulating glucose and lipid metabolism in Sertoli cells.
Luo D, Zhang M, Su X, Liu L, Zhou X, Zhang X, Zheng D, Yu C, Guan Q
Life sciences 2020 Sep 15;257:118028
Life sciences 2020 Sep 15;257:118028
Sphingomyelin Synthase 2 Participate in the Regulation of Sperm Motility and Apoptosis.
Li X, Luo T, Li H, Yan N
Molecules (Basel, Switzerland) 2020 Sep 15;25(18)
Molecules (Basel, Switzerland) 2020 Sep 15;25(18)
Overactivated sonic hedgehog signaling aggravates intrauterine adhesion via inhibiting autophagy in endometrial stromal cells.
Wei C, Pan Y, Zhang Y, Dai Y, Jiang L, Shi L, Yang W, Xu S, Zhang Y, Xu W, Zhang Y, Lin X, Zhang S
Cell death & disease 2020 Sep 15;11(9):755
Cell death & disease 2020 Sep 15;11(9):755
Troxerutin protects against DHT-induced polycystic ovary syndrome in rats.
Gao Z, Ma X, Liu J, Ge Y, Wang L, Fu P, Liu Z, Yao R, Yan X
Journal of ovarian research 2020 Sep 13;13(1):106
Journal of ovarian research 2020 Sep 13;13(1):106
Tectorigenin enhances PDX1 expression and protects pancreatic β-cells by activating ERK and reducing ER stress.
Yao X, Li K, Liang C, Zhou Z, Wang J, Wang S, Liu L, Yu CL, Song ZB, Bao YL, Zheng LH, Sun Y, Wang G, Huang Y, Yi J, Sun L, Li Y
The Journal of biological chemistry 2020 Sep 11;295(37):12975-12992
The Journal of biological chemistry 2020 Sep 11;295(37):12975-12992
The protoapigenone analog WYC0209 targets CD133+ cells: A potential adjuvant agent against cancer stem cells in urothelial cancer therapy.
Yeh BW, Yu LE, Li CC, Yang JC, Li WM, Wu YC, Wei YC, Lee HT, Kung ML, Wu WJ
Toxicology and applied pharmacology 2020 Sep 1;402:115129
Toxicology and applied pharmacology 2020 Sep 1;402:115129
The vicious cycle between ferritinophagy and ROS production triggered EMT inhibition of gastric cancer cells was through p53/AKT/mTor pathway.
Xu Z, Feng J, Li Y, Guan D, Chen H, Zhai X, Zhang L, Li C, Li C
Chemico-biological interactions 2020 Sep 1;328:109196
Chemico-biological interactions 2020 Sep 1;328:109196
Tp53 Suppression Promotes Cardiomyocyte Proliferation during Zebrafish Heart Regeneration.
Shoffner A, Cigliola V, Lee N, Ou J, Poss KD
Cell reports 2020 Sep 1;32(9):108089
Cell reports 2020 Sep 1;32(9):108089
Downregulation of PIF1, a potential new target of MYCN, induces apoptosis and inhibits cell migration in neuroblastoma cells.
Chen B, Hua Z, Gong B, Tan X, Zhang S, Li Q, Chen Y, Zhang J, Li Z
Life sciences 2020 Sep 1;256:117820
Life sciences 2020 Sep 1;256:117820
Four active monomers from Moutan Cortex exert inhibitory effects against oxidative stress by activating Nrf2/Keap1 signaling pathway.
Zhang B, Yu D, Luo N, Yang C, Zhu Y
The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology 2020 Sep 1;24(5):373-384
The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology 2020 Sep 1;24(5):373-384
FERMT1 promotes gastric cancer progression by activating the NF-κB pathway and predicts poor prognosis.
Fan H, Zhang S, Zhang Y, Liang W, Cao B
Cancer biology & therapy 2020 Sep 1;21(9):815-825
Cancer biology & therapy 2020 Sep 1;21(9):815-825
A novel antiviral lncRNA, EDAL, shields a T309 O-GlcNAcylation site to promote EZH2 lysosomal degradation.
Sui B, Chen D, Liu W, Wu Q, Tian B, Li Y, Hou J, Liu S, Xie J, Jiang H, Luo Z, Lv L, Huang F, Li R, Zhang C, Tian Y, Cui M, Zhou M, Chen H, Fu ZF, Zhang Y, Zhao L
Genome biology 2020 Sep 1;21(1):228
Genome biology 2020 Sep 1;21(1):228
Expression Level of Small Envelope Protein in Addition to Sequence Divergence inside Its Major Hydrophilic Region Contributes to More Efficient Surface Antigen Secretion by Hepatitis B Virus Subgenotype D2 than Subgenotype A2.
Wang Q, Fu S, Zhang J, Yuan Q, Li J, Xia N, Wen YM, Wang Y, Tong S
Viruses 2020 Sep 1;12(9)
Viruses 2020 Sep 1;12(9)
Dual targeting of NUAK1 and ULK1 using the multitargeted inhibitor MRT68921 exerts potent antitumor activities.
Chen Y, Xie X, Wang C, Hu Y, Zhang H, Zhang L, Tu S, He Y, Li Y
Cell death & disease 2020 Sep 1;11(8):712
Cell death & disease 2020 Sep 1;11(8):712
miR-142-5p and miR-130a-3p regulate pulmonary macrophage polarization and asthma airway remodeling.
Shi J, Chen M, Ouyang L, Wang Q, Guo Y, Huang L, Jiang S
Immunology and cell biology 2020 Oct;98(9):715-725
Immunology and cell biology 2020 Oct;98(9):715-725
MiR-375-3p alleviates the severity of inflammation through targeting YAP1/LEKTI pathway in HaCaT cells.
Cheng S, Di Z, Hirman AR, Zheng H, Duo L, Zhai Q, Xu J
Bioscience, biotechnology, and biochemistry 2020 Oct;84(10):2005-2013
Bioscience, biotechnology, and biochemistry 2020 Oct;84(10):2005-2013
Genome-wide pathogenesis interpretation using a heat diffusion-based systems genetics method and implications for gene function annotation.
Quan Y, Zhang QY, Lv BM, Xu RF, Zhang HY
Molecular genetics & genomic medicine 2020 Oct;8(10):e1456
Molecular genetics & genomic medicine 2020 Oct;8(10):e1456
Amyotrophic lateral sclerosis-linked UBQLN2 mutants inhibit endoplasmic reticulum to Golgi transport, leading to Golgi fragmentation and ER stress.
Halloran M, Ragagnin AMG, Vidal M, Parakh S, Yang S, Heng B, Grima N, Shahheydari H, Soo KY, Blair I, Guillemin GJ, Sundaramoorthy V, Atkin JD
Cellular and molecular life sciences : CMLS 2020 Oct;77(19):3859-3873
Cellular and molecular life sciences : CMLS 2020 Oct;77(19):3859-3873
Uncovering the mechanism of Astragali Radix against nephrotic syndrome by intergrating lipidomics and network pharmacology.
Li AP, Yang L, Cui T, Zhang LC, Liu YT, Yan Y, Li K, Qin XM
Phytomedicine : international journal of phytotherapy and phytopharmacology 2020 Oct;77:153274
Phytomedicine : international journal of phytotherapy and phytopharmacology 2020 Oct;77:153274
Senolytic Agent Navitoclax Inhibits Angiotensin II-Induced Heart Failure in Mice.
Jia K, Dai Y, Liu A, Li X, Wu L, Lu L, Bao Y, Jin Q
Journal of cardiovascular pharmacology 2020 Oct;76(4):452-460
Journal of cardiovascular pharmacology 2020 Oct;76(4):452-460
miR-29b-3p protects cardiomyocytes against endotoxin-induced apoptosis and inflammatory response through targeting FOXO3A.
Li Z, Yi N, Chen R, Meng Y, Wang Y, Liu H, Cao W, Hu Y, Gu Y, Tong C, Lu M, Li L, Peng L
Cellular signalling 2020 Oct;74:109716
Cellular signalling 2020 Oct;74:109716
MYCT1 inhibits the EMT and migration of laryngeal cancer cells via the SP1/miR-629-3p/ESRP2 pathway.
Yue PJ, Sun YY, Li YH, Xu ZM, Fu WN
Cellular signalling 2020 Oct;74:109709
Cellular signalling 2020 Oct;74:109709
Blocking NFATc3 ameliorates azoxymethane/dextran sulfate sodium induced colitis-associated colorectal cancer in mice via the inhibition of inflammatory responses and epithelial-mesenchymal transition.
Lin Y, Koumba MH, Qu S, Wang D, Lin L
Cellular signalling 2020 Oct;74:109707
Cellular signalling 2020 Oct;74:109707
Identification of mecciRNAs and their roles in the mitochondrial entry of proteins.
Liu X, Wang X, Li J, Hu S, Deng Y, Yin H, Bao X, Zhang QC, Wang G, Wang B, Shi Q, Shan G
Science China. Life sciences 2020 Oct;63(10):1429-1449
Science China. Life sciences 2020 Oct;63(10):1429-1449
The support of genetic evidence for cardiovascular risk induced by antineoplastic drugs.
Cui H, Zuo S, Liu Z, Liu H, Wang J, You T, Zheng Z, Zhou Y, Qian X, Yao H, Xie L, Liu T, Sham PC, Yu Y, Li MJ
Science advances 2020 Oct;6(42)
Science advances 2020 Oct;6(42)
Upregulation of secreted phosphoprotein 1 affects malignant progression, prognosis, and resistance to cetuximab via the KRAS/MEK pathway in head and neck cancer.
Liu K, Hu H, Jiang H, Liu C, Zhang H, Gong S, Wei D, Yu Z
Molecular carcinogenesis 2020 Oct;59(10):1147-1158
Molecular carcinogenesis 2020 Oct;59(10):1147-1158
MiR-34a suppresses the proliferation and invasion of gastric cancer by modulating PDL1 in the immune microenvironment.
Yong H, Fu J, Gao G, Shi H, Zheng D, Zhou X
Molecular and cellular probes 2020 Oct;53:101601
Molecular and cellular probes 2020 Oct;53:101601
Bovine Milk Exosomes Affect Proliferation and Protect Macrophages against Cisplatin-Induced Cytotoxicity.
Matic S, D'Souza DH, Wu T, Pangloli P, Dia VP
Immunological investigations 2020 Oct;49(7):711-725
Immunological investigations 2020 Oct;49(7):711-725
Generation of homozygous CRISPRa human induced pluripotent stem cell (hiPSC) lines for sustained endogenous gene activation.
Schoger E, Argyriou L, Zimmermann WH, Cyganek L, Zelarayán LC
Stem cell research 2020 Oct;48:101944
Stem cell research 2020 Oct;48:101944
sATP‑binding cassette subfamily G member 2 enhances the multidrug resistance properties of human nasal natural killer/T cell lymphoma side population cells.
Wu S, Zhang X, Dong M, Yang Z, Zhang M, Chen Q
Oncology reports 2020 Oct;44(4):1467-1478
Oncology reports 2020 Oct;44(4):1467-1478
NLRC3 silencing accelerates the invasion of hepatocellular carcinoma cell via IL-6/JAK2/STAT3 pathway activation.
Kang JH, Li MJ, Luan PP, Jiang DK, Chen YW, Xu X, Yu Q, Xu YW, Su Q, Peng WH, Jian WX
Cell biology international 2020 Oct;44(10):2053-2064
Cell biology international 2020 Oct;44(10):2053-2064
Internalization of the TAT-PBX1 fusion protein significantly enhances the proliferation of human hair follicle-derived mesenchymal stem cells and delays their senescence.
Wang B, Liu F, Liu Z, Han X, Lian A, Zhang Y, Zuo K, Wang Y, Liu M, Zou F, Jiang Y, Jin M, Liu X, Liu J
Biotechnology letters 2020 Oct;42(10):1877-1885
Biotechnology letters 2020 Oct;42(10):1877-1885
Pellino1 Contributes to Morphine Tolerance by Microglia Activation via MAPK Signaling in the Spinal Cord of Mice.
Wang L, Yin C, Xu X, Liu T, Wang B, Abdul M, Zhou Y, Cao J, Lu C
Cellular and molecular neurobiology 2020 Oct;40(7):1117-1131
Cellular and molecular neurobiology 2020 Oct;40(7):1117-1131
Tissue Inhibitor of Metalloprotease-1 (TIMP-1) Regulates Adipogenesis of Adipose-derived Stem Cells (ASCs) via the Wnt Signaling Pathway in an MMP-independent Manner.
Wang L, Zhang CG, Jia YL, Hu L
Current medical science 2020 Oct;40(5):989-996
Current medical science 2020 Oct;40(5):989-996
3-Methyladenine Alleviates Experimental Subretinal Fibrosis by Inhibiting Macrophages and M2 Polarization Through the PI3K/Akt Pathway.
Bo Q, Shen M, Xiao M, Liang J, Zhai Y, Zhu H, Jiang M, Wang F, Luo X, Sun X
Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 2020 Oct;36(8):618-628
Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 2020 Oct;36(8):618-628
The role of Caspase-1/GSDMD-mediated pyroptosis in Taxol-induced cell death and a Taxol-resistant phenotype in nasopharyngeal carcinoma regulated by autophagy.
Wang X, Li H, Li W, Xie J, Wang F, Peng X, Song Y, Tan G
Cell biology and toxicology 2020 Oct;36(5):437-457
Cell biology and toxicology 2020 Oct;36(5):437-457
Zbtb20 deficiency causes cardiac contractile dysfunction in mice.
Ren AJ, Chen C, Zhang S, Liu M, Wei C, Wang K, Ma X, Song Y, Wang R, Zhang H, Chen YX, Wu H, Xie Z, Zhang Y, Zhang WJ
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Oct;34(10):13862-13876
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Oct;34(10):13862-13876
Endothelial microparticles induced by cyclic stretch activate Src and modulate cell apoptosis.
Zhuang F, Bao H, Shi Q, Li J, Jiang ZL, Wang Y, Qi YX
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Oct;34(10):13586-13596
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Oct;34(10):13586-13596
Xanthatin alleviates airway inflammation in asthmatic mice by regulating the STAT3/NF-κB signaling pathway.
Chang J, Gao J, Lou L, Chu H, Li P, Chen T, Gao F
Respiratory physiology & neurobiology 2020 Oct;281:103491
Respiratory physiology & neurobiology 2020 Oct;281:103491
Curcumin suppresses the proliferation and tumorigenicity of Cal27 by modulating cancer-associated fibroblasts of TSCC.
Ba P, Xu M, Yu M, Li L, Duan X, Lv S, Fu G, Yang J, Yang P, Yang C, Sun Q
Oral diseases 2020 Oct;26(7):1375-1383
Oral diseases 2020 Oct;26(7):1375-1383
Aloe extract inhibits porcine epidemic diarrhea virus in vitro and in vivo.
Xu Z, Liu Y, Peng P, Liu Y, Huang M, Ma Y, Xue C, Cao Y
Veterinary microbiology 2020 Oct;249:108849
Veterinary microbiology 2020 Oct;249:108849
Emodin inhibiting neutrophil elastase-induced epithelial-mesenchymal transition through Notch1 signalling in alveolar epithelial cells.
Zhou L, Gao R, Hong H, Li X, Yang J, Shen W, Wang Z, Yang J
Journal of cellular and molecular medicine 2020 Oct;24(20):11998-12007
Journal of cellular and molecular medicine 2020 Oct;24(20):11998-12007
Ulinastatin reduces myocardial injury induced by doxorubicin in SD rats.
Zhu JG, Jin K, Ren Y
European review for medical and pharmacological sciences 2020 Oct;24(20):10769-10778
European review for medical and pharmacological sciences 2020 Oct;24(20):10769-10778
Selective blocking of CXCR2 prevents and reverses atrial fibrillation in spontaneously hypertensive rats.
Zhang YL, Teng F, Han X, Li PB, Yan X, Guo SB, Li HH
Journal of cellular and molecular medicine 2020 Oct;24(19):11272-11282
Journal of cellular and molecular medicine 2020 Oct;24(19):11272-11282
Circular RNA circTET3 mediates migration of rat vascular smooth muscle cells by targeting miR-351-5p.
Yao QP, Liu Z, Yao AH, Liu JT, Jiang J, Chen Y, Li SS, Han Y, Jiang ZL, Qi YX
Journal of cellular physiology 2020 Oct;235(10):6831-6842
Journal of cellular physiology 2020 Oct;235(10):6831-6842
Resveratrol inhibits hypertrophic scars formation by activating autophagy via the miR-4654/Rheb axis.
Pang K, Li B, Tang Z, Yang W, Hao L, Shi Z, Zhang J, Cai L, Li R, Liu Y, Lv Q, Ding J, Han C
Molecular medicine reports 2020 Oct;22(4):3440-3452
Molecular medicine reports 2020 Oct;22(4):3440-3452
PRDX2 plays an oncogenic role in esophageal squamous cell carcinoma via Wnt/β-catenin and AKT pathways.
Feng AL, Han X, Meng X, Chen Z, Li Q, Shu W, Dai H, Zhu J, Yang Z
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 2020 Oct;22(10):1838-1848
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 2020 Oct;22(10):1838-1848
Autophagy-Sirt3 axis decelerates hematopoietic aging.
Fang Y, An N, Zhu L, Gu Y, Qian J, Jiang G, Zhao R, Wei W, Xu L, Zhang G, Yao X, Yuan N, Zhang S, Zhao Y, Wang J
Aging cell 2020 Oct;19(10):e13232
Aging cell 2020 Oct;19(10):e13232
Over-activation of NMDA receptors promotes ABCA1 degradation and foam cell formation.
Cheng H, Cheng Q, Bao X, Luo Y, Zhou Y, Li Y, Hua Q, Liu W, Tang S, Feng D, Luo Z
Biochimica et biophysica acta. Molecular and cell biology of lipids 2020 Oct;1865(10):158778
Biochimica et biophysica acta. Molecular and cell biology of lipids 2020 Oct;1865(10):158778
ML-SA1, a selective TRPML agonist, inhibits DENV2 and ZIKV by promoting lysosomal acidification and protease activity.
Xia Z, Wang L, Li S, Tang W, Sun F, Wu Y, Miao L, Cao Z
Antiviral research 2020 Oct;182:104922
Antiviral research 2020 Oct;182:104922
Perillaldehyde: A promising antifungal agent to treat oropharyngeal candidiasis.
Chen L, Qu S, Yang K, Liu M, Li YX, Keller NP, Zeng X, Tian J
Biochemical pharmacology 2020 Oct;180:114201
Biochemical pharmacology 2020 Oct;180:114201
TGF-β1-induced miR-424 promotes pulmonary myofibroblast differentiation by targeting Slit2 protein expression.
Huang Y, Xie Y, Abel PW, Wei P, Plowman J, Toews ML, Strah H, Siddique A, Bailey KL, Tu Y
Biochemical pharmacology 2020 Oct;180:114172
Biochemical pharmacology 2020 Oct;180:114172
Inhibition of RUNX1 promotes cisplatin-induced apoptosis in ovarian cancer cells.
Xiao L, Peng Z, Zhu A, Xue R, Lu R, Mi J, Xi S, Chen W, Jiang S
Biochemical pharmacology 2020 Oct;180:114116
Biochemical pharmacology 2020 Oct;180:114116
Peli1 impairs microglial Aβ phagocytosis through promoting C/EBPβ degradation.
Xu J, Yu T, Pietronigro EC, Yuan J, Arioli J, Pei Y, Luo X, Ye J, Constantin G, Mao C, Xiao Y
PLoS biology 2020 Oct;18(10):e3000837
PLoS biology 2020 Oct;18(10):e3000837
The Long Noncoding RNA NEAT1 Promotes Sarcoma Metastasis by Regulating RNA Splicing Pathways.
Huang J, Sachdeva M, Xu E, Robinson TJ, Luo L, Ma Y, Williams NT, Lopez O, Cervia LD, Yuan F, Qin X, Zhang D, Owzar K, Gokgoz N, Seto A, Okada T, Singer S, Andrulis IL, Wunder JS, Lazar AJ, Rubin BP, Pipho K, Mello SS, Giudice J, Kirsch DG
Molecular cancer research : MCR 2020 Oct;18(10):1534-1544
Molecular cancer research : MCR 2020 Oct;18(10):1534-1544
Antidiabetic activity in vitro and in vivo of BDB, a selective inhibitor of protein tyrosine phosphatase 1B, from Rhodomela confervoides.
Luo J, Zheng M, Jiang B, Li C, Guo S, Wang L, Li X, Yu R, Shi D
British journal of pharmacology 2020 Oct;177(19):4464-4480
British journal of pharmacology 2020 Oct;177(19):4464-4480
The human ribosomal protein eL29 binds in vivo to the cognate mRNA by interacting with its coding sequence, as revealed from in-cell cross-linking data.
Babaylova ES, Kolobova AV, Gopanenko AV, Tupikin AE, Kabilov MR, Malygin AA, Karpova GG
Biochimie 2020 Oct;177:68-77
Biochimie 2020 Oct;177:68-77
RAGE Signaling pathway in hippocampus dentate gyrus involved in GLT-1 decrease induced by chronic unpredictable stress in rats.
Yang F, Wang H, Chen H, Ran D, Tang Q, Weng P, Sun Y, Jiang W
Brain research bulletin 2020 Oct;163:49-56
Brain research bulletin 2020 Oct;163:49-56
Melatonin improves hypoxic-ischemic brain damage through the Akt/Nrf2/Gpx4 signaling pathway.
Gou Z, Su X, Hu X, Zhou Y, Huang L, Fan Y, Li J, Lu L
Brain research bulletin 2020 Oct;163:40-48
Brain research bulletin 2020 Oct;163:40-48
RNA demethylase Alkbh5 is widely expressed in neurons and decreased during brain development.
Du T, Li G, Yang J, Ma K
Brain research bulletin 2020 Oct;163:150-159
Brain research bulletin 2020 Oct;163:150-159
Inhibition of cell migration and induction of apoptosis by a novel class II histone deacetylase inhibitor, MCC2344.
Dawood M, Fleischer E, Klinger A, Bringmann G, Shan L, Efferth T
Pharmacological research 2020 Oct;160:105076
Pharmacological research 2020 Oct;160:105076
Enhancing PPARγ by HDAC inhibition reduces foam cell formation and atherosclerosis in ApoE deficient mice.
Gao Q, Wei A, Chen F, Chen X, Ding W, Ding Z, Wu Z, Du R, Cao W
Pharmacological research 2020 Oct;160:105059
Pharmacological research 2020 Oct;160:105059
p53 promotes ZDHHC1-mediated IFITM3 palmitoylation to inhibit Japanese encephalitis virus replication.
Wang X, Wu Z, Li Y, Yang Y, Xiao C, Liu X, Xiang X, Wei J, Shao D, Liu K, Deng X, Wu J, Qiu Y, Li B, Ma Z
PLoS pathogens 2020 Oct;16(10):e1009035
PLoS pathogens 2020 Oct;16(10):e1009035
STYK1 promotes autophagy through enhancing the assembly of autophagy-specific class III phosphatidylinositol 3-kinase complex I.
Zhou C, Qian X, Hu M, Zhang R, Liu N, Huang Y, Yang J, Zhang J, Bai H, Yang Y, Wang Y, Ali D, Michalak M, Chen XZ, Tang J
Autophagy 2020 Oct;16(10):1786-1806
Autophagy 2020 Oct;16(10):1786-1806
Identification of osalmid metabolic profile and active metabolites with anti-tumor activity in human hepatocellular carcinoma cells.
Wu Z, Zhan Y, Wang L, Tong J, Zhang L, Lin M, Jin X, Jiang L, Lou Y, Qiu Y
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Oct;130:110556
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Oct;130:110556
Therapeutic effect of phycocyanin on acute liver oxidative damage caused by X-ray.
Liu Q, Li W, Qin S
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Oct;130:110553
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Oct;130:110553
miR-483-3p promotes cell proliferation and suppresses apoptosis in rheumatoid arthritis fibroblast-like synoviocytes by targeting IGF-1.
Wang Y, Hou L, Yuan X, Xu N, Zhao S, Yang L, Zhang N
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Oct;130:110519
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Oct;130:110519
Paired like homeodomain 1 and SAM and SH3 domain-containing 1 in the progression and prognosis of head and neck squamous cell carcinoma.
Jin Y, Qin X
The international journal of biochemistry & cell biology 2020 Oct;127:105846
The international journal of biochemistry & cell biology 2020 Oct;127:105846
Lnc-MUC20-9 binds to ROCK1 and functions as a tumor suppressor in bladder cancer.
Dai R, Zhou Y, Chen Z, Zou Z, Pan Z, Liu P, Gao X
Journal of cellular biochemistry 2020 Oct;121(10):4214-4225
Journal of cellular biochemistry 2020 Oct;121(10):4214-4225
Matrix metalloprotease-mediated cleavage of neural glial-related cell adhesion molecules activates quiescent olfactory stem cells via EGFR.
Chen ZH, Luo XC, Yu CR, Huang L
Molecular and cellular neurosciences 2020 Oct;108:103552
Molecular and cellular neurosciences 2020 Oct;108:103552
Renal asymmetric dimethylarginine inhibits fibrosis.
Wu M, Yuan M, Wang Y, Tan B, Huang D, Wang C, Zou Y, Ye C
FEBS open bio 2020 Oct;10(10):2003-2009
FEBS open bio 2020 Oct;10(10):2003-2009
Enhancing site-specific DNA integration by a Cas9 nuclease fused with a DNA donor-binding domain.
Ma S, Wang X, Hu Y, Lv J, Liu C, Liao K, Guo X, Wang D, Lin Y, Rong Z
Nucleic acids research 2020 Oct 9;48(18):10590-10601
Nucleic acids research 2020 Oct 9;48(18):10590-10601
Mir-20a-5p induced WTX deficiency promotes gastric cancer progressions through regulating PI3K/AKT signaling pathway.
Li J, Ye D, Shen P, Liu X, Zhou P, Zhu G, Xu Y, Fu Y, Li X, Sun J, Xu J, Zhang Q
Journal of experimental & clinical cancer research : CR 2020 Oct 8;39(1):212
Journal of experimental & clinical cancer research : CR 2020 Oct 8;39(1):212
Calreticulin promotes EMT in pancreatic cancer via mediating Ca(2+) dependent acute and chronic endoplasmic reticulum stress.
Sheng W, Wang G, Tang J, Shi X, Cao R, Sun J, Lin YH, Jia C, Chen C, Zhou J, Dong M
Journal of experimental & clinical cancer research : CR 2020 Oct 7;39(1):209
Journal of experimental & clinical cancer research : CR 2020 Oct 7;39(1):209
miR-431-5p regulates cell proliferation and apoptosis in fibroblast-like synoviocytes in rheumatoid arthritis by targeting XIAP.
Wang Y, Zhang K, Yuan X, Xu N, Zhao S, Hou L, Yang L, Zhang N
Arthritis research & therapy 2020 Oct 6;22(1):231
Arthritis research & therapy 2020 Oct 6;22(1):231
Effect of Zhenxin Xingshui Yizhi Fang on Aβ(25-35) induced expression of related transporters in HBMEC cell model.
Wu L, Zheng Q, Guo YY, Zhang KN, Luo J, Xiao S, Li WJ, Yang M
Journal of ethnopharmacology 2020 Oct 5;260:112783
Journal of ethnopharmacology 2020 Oct 5;260:112783
Loss of TMEM106B and PGRN leads to severe lysosomal abnormalities and neurodegeneration in mice.
Feng T, Mai S, Roscoe JM, Sheng RR, Ullah M, Zhang J, Katz II, Yu H, Xiong W, Hu F
EMBO reports 2020 Oct 5;21(10):e50219
EMBO reports 2020 Oct 5;21(10):e50219
Temporal activation of LRH-1 and RAR-γ in human pluripotent stem cells induces a functional naïve-like state.
Taei A, Kiani T, Taghizadeh Z, Moradi S, Samadian A, Mollamohammadi S, Sharifi-Zarchi A, Guenther S, Akhlaghpour A, Asgari Abibeiglou B, Najar-Asl M, Karamzadeh R, Khalooghi K, Braun T, Hassani SN, Baharvand H
EMBO reports 2020 Oct 5;21(10):e47533
EMBO reports 2020 Oct 5;21(10):e47533
Blockade of Glial Connexin 43 Hemichannels Reduces Food Intake.
Guillebaud F, Barbot M, Barbouche R, Brézun JM, Poirot K, Vasile F, Lebrun B, Rouach N, Dallaporta M, Gaige S, Troadec JD
Cells 2020 Oct 31;9(11)
Cells 2020 Oct 31;9(11)
Defect of SLC38A3 promotes epithelial-mesenchymal transition and predicts poor prognosis in esophageal squamous cell carcinoma.
Liu R, Hong R, Wang Y, Gong Y, Yeerken D, Yang D, Li J, Fan J, Chen J, Zhang W, Zhan Q
Chinese journal of cancer research = Chung-kuo yen cheng yen chiu 2020 Oct 31;32(5):547-563
Chinese journal of cancer research = Chung-kuo yen cheng yen chiu 2020 Oct 31;32(5):547-563
IGF2BP1 silencing inhibits proliferation and induces apoptosis of high glucose-induced non-small cell lung cancer cells by regulating Netrin-1.
Zhang J, Luo W, Chi X, Zhang L, Ren Q, Wang H, Zhang W
Archives of biochemistry and biophysics 2020 Oct 30;693:108581
Archives of biochemistry and biophysics 2020 Oct 30;693:108581
Cancer-associated fibroblasts-derived exosomal miR-17-5p promotes colorectal cancer aggressive phenotype by initiating a RUNX3/MYC/TGF-β1 positive feedback loop.
Zhang Y, Wang S, Lai Q, Fang Y, Wu C, Liu Y, Li Q, Wang X, Gu C, Chen J, Cai J, Li A, Liu S
Cancer letters 2020 Oct 28;491:22-35
Cancer letters 2020 Oct 28;491:22-35
HIF-1α-Mediated Mitophagy Determines ZnO Nanoparticle-Induced Human Osteosarcoma Cell Death both In Vitro and In Vivo.
He G, Pan X, Liu X, Zhu Y, Ma Y, Du C, Liu X, Mao C
ACS applied materials & interfaces 2020 Oct 28;12(43):48296-48309
ACS applied materials & interfaces 2020 Oct 28;12(43):48296-48309
Circular RNA circ_PVT1 induces epithelial-mesenchymal transition to promote metastasis of cervical cancer.
Wang H, Wei M, Kang Y, Xing J, Zhao Y
Aging 2020 Oct 27;12(20):20139-20151
Aging 2020 Oct 27;12(20):20139-20151
Nicotine Causes Nephrotoxicity through the Induction of NLRP6 Inflammasome and Alpha7 Nicotinic Acetylcholine Receptor.
Zheng CM, Lee YH, Chiu IJ, Chiu YJ, Sung LC, Hsu YH, Chiu HW
Toxics 2020 Oct 26;8(4)
Toxics 2020 Oct 26;8(4)
A Dedicated Evolutionarily Conserved Molecular Network Licenses Differentiated Cells to Return to the Cell Cycle.
Miao ZF, Lewis MA, Cho CJ, Adkins-Threats M, Park D, Brown JW, Sun JX, Burclaff JR, Kennedy S, Lu J, Mahar M, Vietor I, Huber LA, Davidson NO, Cavalli V, Rubin DC, Wang ZN, Mills JC
Developmental cell 2020 Oct 26;55(2):178-194.e7
Developmental cell 2020 Oct 26;55(2):178-194.e7
Myostatin regulates fatty acid desaturation and fat deposition through MEF2C/miR222/SCD5 cascade in pigs.
Ren H, Xiao W, Qin X, Cai G, Chen H, Hua Z, Cheng C, Li X, Hua W, Xiao H, Zhang L, Dai J, Zheng X, Zhu Z, Qian C, Yao J, Bi Y
Communications biology 2020 Oct 23;3(1):612
Communications biology 2020 Oct 23;3(1):612
Inhibition of ROS/NLRP3/Caspase-1 mediated pyroptosis attenuates cadmium-induced apoptosis in duck renal tubular epithelial cells.
Wei Z, Nie G, Yang F, Pi S, Wang C, Cao H, Guo X, Liu P, Li G, Hu G, Zhang C
Environmental pollution (Barking, Essex : 1987) 2020 Oct 23;273:115919
Environmental pollution (Barking, Essex : 1987) 2020 Oct 23;273:115919
PD-1 Regulates GABAergic Neurotransmission and GABA-Mediated Analgesia and Anesthesia.
Jiang C, Wang Z, Donnelly CR, Wang K, Andriessen AS, Tao X, Matsuda M, Zhao J, Ji RR
iScience 2020 Oct 23;23(10):101570
iScience 2020 Oct 23;23(10):101570
USP52 regulates DNA end resection and chemosensitivity through removing inhibitory ubiquitination from CtIP.
Gao M, Guo G, Huang J, Kloeber JA, Zhao F, Deng M, Tu X, Kim W, Zhou Q, Zhang C, Yin P, Luo K, Lou Z
Nature communications 2020 Oct 23;11(1):5362
Nature communications 2020 Oct 23;11(1):5362
Functional validation of a human GLUD2 variant in a murine model of Parkinson's disease.
Zhang W, Gong J, Ding L, Zhang Z, Pan X, Chen X, Guo W, Zhang X, Yang X, Peng G, Lin Y, Gao F, Li Y, Zhu X, Xuan A, Wang S, Sun X, Zhang Y, Xu P
Cell death & disease 2020 Oct 22;11(10):897
Cell death & disease 2020 Oct 22;11(10):897
Phosphodiesterase 2A2 regulates mitochondria clearance through Parkin-dependent mitophagy.
Lobo MJ, Reverte-Salisa L, Chao YC, Koschinski A, Gesellchen F, Subramaniam G, Jiang H, Pace S, Larcom N, Paolocci E, Pfeifer A, Zanivan S, Zaccolo M
Communications biology 2020 Oct 21;3(1):596
Communications biology 2020 Oct 21;3(1):596
Loss of PRCD alters number and packaging density of rhodopsin in rod photoreceptor disc membranes.
Sechrest ER, Murphy J, Senapati S, Goldberg AFX, Park PS, Kolandaivelu S
Scientific reports 2020 Oct 21;10(1):17885
Scientific reports 2020 Oct 21;10(1):17885
Emergence of Carbapenem-Resistant Providencia rettgeri and Providencia stuartii Producing IMP-Type Metallo-β-Lactamase in Japan.
Iwata S, Tada T, Hishinuma T, Tohya M, Oshiro S, Kuwahara-Arai K, Ogawa M, Shimojima M, Kirikae T
Antimicrobial agents and chemotherapy 2020 Oct 20;64(11)
Antimicrobial agents and chemotherapy 2020 Oct 20;64(11)
A Regulation Loop between YAP and NR4A1 Balances Cell Proliferation and Apoptosis.
He L, Yuan L, Yu W, Sun Y, Jiang D, Wang X, Feng X, Wang Z, Xu J, Yang R, Zhang W, Feng H, Chen HZ, Zeng YA, Hui L, Wu Q, Zhang Y, Zhang L
Cell reports 2020 Oct 20;33(3):108284
Cell reports 2020 Oct 20;33(3):108284
Novel Therapeutic Insights in Dedifferentiated Liposarcoma: A Role for FGFR and MDM2 Dual Targeting.
Dadone-Montaudié B, Laroche-Clary A, Mongis A, Chamorey E, Mauro ID, Chaire V, Finetti P, Schiappa R, Le Loarer F, Birtwisle-Peyrottes I, Michiels JF, Bertucci F, Pedeutour F, Italiano A, Bianchini L
Cancers 2020 Oct 20;12(10)
Cancers 2020 Oct 20;12(10)
Targeting interleukin-17 receptor B enhances gemcitabine sensitivity through downregulation of mucins in pancreatic cancer.
Tsai LH, Hsu KW, Chiang CM, Yang HJ, Liu YH, Yang SF, Peng PH, Cheng WC, Wu HH
Scientific reports 2020 Oct 20;10(1):17817
Scientific reports 2020 Oct 20;10(1):17817
Expression of STAT1 is positively correlated with PD-L1 in human ovarian cancer.
Liu F, Liu J, Zhang J, Shi J, Gui L, Xu G
Cancer biology & therapy 2020 Oct 2;21(10):963-971
Cancer biology & therapy 2020 Oct 2;21(10):963-971
Multiple-Purpose Connectivity Map Analysis Reveals the Benefits of Esculetin to Hyperuricemia and Renal Fibrosis.
Wang Y, Kong W, Wang L, Zhang T, Huang B, Meng J, Yang B, Xie Z, Zhou H
International journal of molecular sciences 2020 Oct 18;21(20)
International journal of molecular sciences 2020 Oct 18;21(20)
Quality Control of ER Membrane Proteins by the RNF185/Membralin Ubiquitin Ligase Complex.
van de Weijer ML, Krshnan L, Liberatori S, Guerrero EN, Robson-Tull J, Hahn L, Lebbink RJ, Wiertz EJHJ, Fischer R, Ebner D, Carvalho P
Molecular cell 2020 Oct 15;80(2):374-375
Molecular cell 2020 Oct 15;80(2):374-375
Antioxidant Apigenin Relieves Age-Related Muscle Atrophy by Inhibiting Oxidative Stress and Hyperactive Mitophagy and Apoptosis in Skeletal Muscle of Mice.
Wang D, Yang Y, Zou X, Zhang J, Zheng Z, Wang Z
The journals of gerontology. Series A, Biological sciences and medical sciences 2020 Oct 15;75(11):2081-2088
The journals of gerontology. Series A, Biological sciences and medical sciences 2020 Oct 15;75(11):2081-2088
Autophagy regulates exosome secretion in rat nucleus pulposus cells via the RhoC/ROCK2 pathway.
Hu SQ, Zhang QC, Meng QB, Hu AN, Zou JP, Li XL
Experimental cell research 2020 Oct 15;395(2):112239
Experimental cell research 2020 Oct 15;395(2):112239
SARS-CoV-2 targets neurons of 3D human brain organoids.
Ramani A, Müller L, Ostermann PN, Gabriel E, Abida-Islam P, Müller-Schiffmann A, Mariappan A, Goureau O, Gruell H, Walker A, Andrée M, Hauka S, Houwaart T, Dilthey A, Wohlgemuth K, Omran H, Klein F, Wieczorek D, Adams O, Timm J, Korth C, Schaal H, Gopalakrishnan J
The EMBO journal 2020 Oct 15;39(20):e106230
The EMBO journal 2020 Oct 15;39(20):e106230
XK is a partner for VPS13A: a molecular link between Chorea-Acanthocytosis and McLeod Syndrome.
Park JS, Neiman AM
Molecular biology of the cell 2020 Oct 15;31(22):2425-2436
Molecular biology of the cell 2020 Oct 15;31(22):2425-2436
Ambient fine particulate matter induced the elevation of blood pressure through ACE2/Ang(1-7) pathway: The evidence from urine metabolites.
Du X, Zeng X, Zhang J, Pan K, Song L, Zhou J, Zhou L, Xie Y, Sun Q, Ge W, Chen R, Zhao J, Kan H
Ecotoxicology and environmental safety 2020 Oct 15;203:111044
Ecotoxicology and environmental safety 2020 Oct 15;203:111044
A novel pectin from Polygala tenuifolia blocks Aβ(42) aggregation and production by enhancing insulin-degradation enzyme and neprilysin.
Zeng H, Li P, Zhou L, Ding K
International journal of biological macromolecules 2020 Oct 15;161:35-43
International journal of biological macromolecules 2020 Oct 15;161:35-43
Structures and anti-atherosclerotic effects of 1,6-α-glucans from Fructus Corni.
Zhang XW, Sui Y, Liu XX, Fu CY, Qiao YH, Liu WJ, Li ZZ, Li XQ, Cao W
International journal of biological macromolecules 2020 Oct 15;161:1346-1357
International journal of biological macromolecules 2020 Oct 15;161:1346-1357
Melatonin suppresses ER stress-dependent proapoptotic effects via AMPK in bone mesenchymal stem cells during mitochondrial oxidative damage.
Fan C, Feng J, Tang C, Zhang Z, Feng Y, Duan W, Zhai M, Yan Z, Zhu L, Feng L, Zhu H, Luo E
Stem cell research & therapy 2020 Oct 15;11(1):442
Stem cell research & therapy 2020 Oct 15;11(1):442
BKCa channels regulate the immunomodulatory properties of WJ-MSCs by affecting the exosome protein profiles during the inflammatory response.
Song A, Wang J, Tong Y, Fang J, Zhang Y, Zhang H, Ruan H, Wang K, Liu Y
Stem cell research & therapy 2020 Oct 15;11(1):440
Stem cell research & therapy 2020 Oct 15;11(1):440
Identification of Fibroblast Activation Protein as an Osteogenic Suppressor and Anti-osteoporosis Drug Target.
Wei H, Xu Y, Wang Y, Xu L, Mo C, Li L, Shen B, Sun Y, Cheng P, Yang L, Pang Y, Qin A, Cao Y, Morrison SJ, Yue R
Cell reports 2020 Oct 13;33(2):108252
Cell reports 2020 Oct 13;33(2):108252
PERK controls bone homeostasis through the regulation of osteoclast differentiation and function.
Guo J, Ren R, Sun K, Yao X, Lin J, Wang G, Guo Z, Xu T, Guo F
Cell death & disease 2020 Oct 13;11(10):847
Cell death & disease 2020 Oct 13;11(10):847
The combined usage of Matrine and Osthole inhibited endoplasmic reticulum apoptosis induced by PCV2.
Xu Y, Sun P, Wan S, Guo J, Zheng X, Sun Y, Fan K, Yin W, Sun N, Li H
BMC microbiology 2020 Oct 12;20(1):303
BMC microbiology 2020 Oct 12;20(1):303
TAp63α targeting of Lgr5 mediates colorectal cancer stem cell properties and sulforaphane inhibition.
Chen Y, Wang MH, Zhu JY, Xie CF, Li XT, Wu JS, Geng SS, Han HY, Zhong CY
Oncogenesis 2020 Oct 10;9(10):89
Oncogenesis 2020 Oct 10;9(10):89
USP7 mediates pathological hepatic de novo lipogenesis through promoting stabilization and transcription of ZNF638.
Ni W, Lin S, Bian S, Zheng W, Qu L, Fan Y, Lu C, Xiao M, Zhou P
Cell death & disease 2020 Oct 10;11(10):843
Cell death & disease 2020 Oct 10;11(10):843
Landscape characterization of chimeric RNAs in colorectal cancer.
Wu H, Singh S, Xie Z, Li X, Li H
Cancer letters 2020 Oct 1;489:56-65
Cancer letters 2020 Oct 1;489:56-65
The RNA exosome complex degrades expanded hexanucleotide repeat RNA in C9orf72 FTLD/ALS.
Kawabe Y, Mori K, Yamashita T, Gotoh S, Ikeda M
The EMBO journal 2020 Oct 1;39(19):e102700
The EMBO journal 2020 Oct 1;39(19):e102700
3-Mercaptopyruvate sulfurtransferase/hydrogen sulfide protects cerebral endothelial cells against oxygen-glucose deprivation/reoxygenation-induced injury via mitoprotection and inhibition of the RhoA/ROCK pathway.
Zhang F, Chen S, Wen JY, Chen ZW
American journal of physiology. Cell physiology 2020 Oct 1;319(4):C720-C733
American journal of physiology. Cell physiology 2020 Oct 1;319(4):C720-C733
Type 2 diabetes-induced overactivation of P300 contributes to skeletal muscle atrophy by inhibiting autophagic flux.
Fan Z, Wu J, Chen QN, Lyu AK, Chen JL, Sun Y, Lyu Q, Zhao YX, Guo A, Liao ZY, Yang YF, Zhu SY, Jiang XS, Chen B, Xiao Q
Life sciences 2020 Oct 1;258:118243
Life sciences 2020 Oct 1;258:118243
Role and mechanism of PI3K/AKT/FoxO1/PDX-1 signaling pathway in functional changes of pancreatic islets in rats after severe burns.
Zhang B, Sun P, Shen C, Liu X, Sun J, Li D, Liu Z, Zhang W, Zhang K, Niu Y
Life sciences 2020 Oct 1;258:118145
Life sciences 2020 Oct 1;258:118145
Platycodon grandifloras polysaccharides inhibit mitophagy injury induced by Cr (VI) in DF-1 cells.
Hao J, Song Y, Tian B, Qi C, Li L, Wang L, Xing Y, Zhao X, Liu J
Ecotoxicology and environmental safety 2020 Oct 1;202:110901
Ecotoxicology and environmental safety 2020 Oct 1;202:110901
Targeting Mitochondria-Located circRNA SCAR Alleviates NASH via Reducing mROS Output.
Zhao Q, Liu J, Deng H, Ma R, Liao JY, Liang H, Hu J, Li J, Guo Z, Cai J, Xu X, Gao Z, Su S
Cell 2020 Oct 1;183(1):76-93.e22
Cell 2020 Oct 1;183(1):76-93.e22
Amifostine ameliorates induction of experimental autoimmune encephalomyelitis: Effect on reactive oxygen species/NLRP3 pathway.
Li J, Wu DM, Yu Y, Deng SH, Liu T, Zhang T, He M, Zhao YY, Xu Y
International immunopharmacology 2020 Nov;88:106998
International immunopharmacology 2020 Nov;88:106998
microRNA-421-3p prevents inflammatory response in cerebral ischemia/reperfusion injury through targeting m6A Reader YTHDF1 to inhibit p65 mRNA translation.
Zheng L, Tang X, Lu M, Sun S, Xie S, Cai J, Zan J
International immunopharmacology 2020 Nov;88:106937
International immunopharmacology 2020 Nov;88:106937
Wilms' tumor 1-associating protein contributes to psoriasis by promoting keratinocytes proliferation via regulating cyclinA2 and CDK2.
Kong Y, Wu R, Zhang S, Zhao M, Wu H, Lu Q, Fu S, Su Y
International immunopharmacology 2020 Nov;88:106918
International immunopharmacology 2020 Nov;88:106918
PDLIM2 protects articular chondrocytes from lipopolysaccharide-induced apoptosis, degeneration and inflammatory injury through down-regulation of nuclear factor (NF)-κB signaling.
Guo Q, Xu J, Shi Q, Wu S
International immunopharmacology 2020 Nov;88:106883
International immunopharmacology 2020 Nov;88:106883
Emodin ameliorates ovalbumin-induced airway remodeling in mice by suppressing airway smooth muscle cells proliferation.
Liu Y, Li X, He C, Chen R, Wei L, Meng L, Zhang C
International immunopharmacology 2020 Nov;88:106855
International immunopharmacology 2020 Nov;88:106855
The role of WNT1 mutant variant (WNT1(c.677C>T) ) in osteogenesis imperfecta.
Zhang B, Li R, Wang W, Zhou X, Luo B, Zhu Z, Zhang X, Ding A
Annals of human genetics 2020 Nov;84(6):447-455
Annals of human genetics 2020 Nov;84(6):447-455
Ginsenoside Rg3 attenuates ovariectomy-induced osteoporosis via AMPK/mTOR signaling pathway.
Zhang X, Huang F, Chen X, Wu X, Zhu J
Drug development research 2020 Nov;81(7):875-884
Drug development research 2020 Nov;81(7):875-884
RSPO3 is a marker candidate for predicting tumor aggressiveness in ovarian cancer.
Gu H, Tu H, Liu L, Liu T, Liu Z, Zhang W, Liu J
Annals of translational medicine 2020 Nov;8(21):1351
Annals of translational medicine 2020 Nov;8(21):1351
SOX2 promotes resistance of melanoma with PD-L1 high expression to T-cell-mediated cytotoxicity that can be reversed by SAHA.
Wu R, Wang C, Li Z, Xiao J, Li C, Wang X, Kong P, Cao J, Huang F, Li Z, Huang Y, Chen Y, Li X, Yang D, Zhang H, Mai J, Feng G, Deng R, Zhu X
Journal for immunotherapy of cancer 2020 Nov;8(2)
Journal for immunotherapy of cancer 2020 Nov;8(2)
The metabolic response to inflammation in astrocytes is regulated by nuclear factor-kappa B signaling.
Robb JL, Hammad NA, Weightman Potter PG, Chilton JK, Beall C, Ellacott KLJ
Glia 2020 Nov;68(11):2246-2263
Glia 2020 Nov;68(11):2246-2263
miR-877-5p antagonizes the promoting effect of SP on the gastric cancer progression.
Guo XD, Zhang N, Sha L
Neoplasma 2020 Nov;67(6):1293-1302
Neoplasma 2020 Nov;67(6):1293-1302
The molecular basis of tight nuclear tethering and inactivation of cGAS.
Zhao B, Xu P, Rowlett CM, Jing T, Shinde O, Lei Y, West AP, Liu WR, Li P
Nature 2020 Nov;587(7835):673-677
Nature 2020 Nov;587(7835):673-677
Loss of core fucosylation enhances the anticancer activity of cytotoxic T lymphocytes by increasing PD-1 degradation.
Zhang N, Li M, Xu X, Zhang Y, Liu Y, Zhao M, Li P, Chen J, Fukuda T, Gu J, Jin X, Li W
European journal of immunology 2020 Nov;50(11):1820-1833
European journal of immunology 2020 Nov;50(11):1820-1833
N‑linoleyltyrosine protects PC12 cells against oxidative damage via autophagy: Possible involvement of CB1 receptor regulation.
Liu X, Wu Y, Zhou D, Xie Y, Zhou Y, Lu Y, Yang R, Liu S
International journal of molecular medicine 2020 Nov;46(5):1827-1837
International journal of molecular medicine 2020 Nov;46(5):1827-1837
Association of tricellulin expression with poor colorectal cancer prognosis and metastasis.
Zhang JX, Qin MB, Ye Z, Peng P, Li SM, Song Q, Lin L, Liu SQ, Xie LH, Zhu Y, Huang JA
Oncology reports 2020 Nov;44(5):2174-2184
Oncology reports 2020 Nov;44(5):2174-2184
Caveolin-1 upregulates Fut8 expression by activating the Wnt/β-catenin pathway to enhance HCC cell proliferative and invasive ability.
Zhang C, Wu Q, Huang H, Chen X, Huang T, Li W, Zhang J, Liu Y
Cell biology international 2020 Nov;44(11):2202-2212
Cell biology international 2020 Nov;44(11):2202-2212
MG53 protects against contrast-induced acute kidney injury by reducing cell membrane damage and apoptosis.
Liu C, Hu YH, Han Y, Wang YB, Zhang Y, Zhang XQ, He DF, Ren HM, Liu YK, Wang HY, Tan T, Lin PH, Li HC, Rovin BH, Ma JJ, Zeng CY
Acta pharmacologica Sinica 2020 Nov;41(11):1457-1464
Acta pharmacologica Sinica 2020 Nov;41(11):1457-1464
The role of protein kinase C alpha in tri-ortho-cresyl phosphate-induced autophagy in human neuroblastoma SK-N-SH cells.
Deng Q, Jiang L, Mao L, Song XH, He CQ, Li XL, Zhang ZH, Zeng HC, Chen JX, Long DX
Journal of applied toxicology : JAT 2020 Nov;40(11):1480-1490
Journal of applied toxicology : JAT 2020 Nov;40(11):1480-1490
Nanog mediates tobacco smoke-induced enhancement of renal cancer stem cell properties.
Zhang T, Sun H, Liu R, Cao W, Zhang T, Li E, Sun X, Wu W, Yu D, Zhong C
Environmental toxicology 2020 Nov;35(11):1274-1283
Environmental toxicology 2020 Nov;35(11):1274-1283
In vivo immunotoxicity of Gd(2) O(3) :Eu(3+) nanoparticles and the associated molecular mechanism.
Zheng C, Tian X, Cai J, Huang L, Wang S, Yang F, Ma Y, Xie F, Li L
Journal of biochemical and molecular toxicology 2020 Nov;34(11):e22562
Journal of biochemical and molecular toxicology 2020 Nov;34(11):e22562
SNORA71B promotes breast cancer cells across blood-brain barrier by inducing epithelial-mesenchymal transition.
Duan S, Luo X, Zeng H, Zhan X, Yuan C
Breast cancer (Tokyo, Japan) 2020 Nov;27(6):1072-1081
Breast cancer (Tokyo, Japan) 2020 Nov;27(6):1072-1081
RBMX is required for activation of ATR on repetitive DNAs to maintain genome stability.
Zheng T, Zhou H, Li X, Peng D, Yang Y, Zeng Y, Liu H, Ren J, Zhao Y
Cell death and differentiation 2020 Nov;27(11):3162-3176
Cell death and differentiation 2020 Nov;27(11):3162-3176
MyoD1 suppresses cell migration and invasion by inhibiting FUT4 transcription in human gastric cancer cells.
Wu F, Qin Y, Jiang Q, Zhang J, Li F, Li Q, Wang X, Gao Y, Miao J, Guo C, Yang Y, Ni L, Liu L, Zhang S, Huang C
Cancer gene therapy 2020 Nov;27(10-11):773-784
Cancer gene therapy 2020 Nov;27(10-11):773-784
TRPV4 promotes acoustic wave-mediated BBB opening via Ca(2+)/PKC-δ pathway.
Liao WH, Hsiao MY, Kung Y, Liu HL, Béra JC, Inserra C, Chen WS
Journal of advanced research 2020 Nov;26:15-28
Journal of advanced research 2020 Nov;26:15-28
Hydroquinone inhibits PRV infection in neurons in vitro and in vivo.
Fang L, Gao Y, Lan M, Jiang P, Bai J, Li Y, Wang X
Veterinary microbiology 2020 Nov;250:108864
Veterinary microbiology 2020 Nov;250:108864
ndufa7 plays a critical role in cardiac hypertrophy.
Shi X, Zhang Y, Chen R, Gong Y, Zhang M, Guan R, Rotstein OD, Liu X, Wen XY
Journal of cellular and molecular medicine 2020 Nov;24(22):13151-13162
Journal of cellular and molecular medicine 2020 Nov;24(22):13151-13162
Down-regulated HDAC3 elevates microRNA-495-3p to restrain epithelial-mesenchymal transition and oncogenicity of melanoma cells via reducing TRAF5.
Ma Y, Duan J, Hao X
Journal of cellular and molecular medicine 2020 Nov;24(22):12933-12944
Journal of cellular and molecular medicine 2020 Nov;24(22):12933-12944
Long noncoding RNA TCONS-00106987 promotes atrial electrical remodelling during atrial fibrillation by sponging miR-26 to regulate KCNJ2.
Du J, Li Z, Wang X, Li J, Liu D, Wang X, Wei J, Ma S, Zhang Y, Hou Y
Journal of cellular and molecular medicine 2020 Nov;24(21):12777-12788
Journal of cellular and molecular medicine 2020 Nov;24(21):12777-12788
Cathepsin L promotes angiogenesis by regulating the CDP/Cux/VEGF-D pathway in human gastric cancer.
Pan T, Jin Z, Yu Z, Wu X, Chang X, Fan Z, Li F, Wang X, Li Z, Zhou Q, Li J, Liu B, Su L
Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association 2020 Nov;23(6):974-987
Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association 2020 Nov;23(6):974-987
Overexpression of G3BP1 facilitates the progression of colon cancer by activating β‑catenin signaling.
Li Y, Wang J, Zhong S, Li J, Du W
Molecular medicine reports 2020 Nov;22(5):4403-4411
Molecular medicine reports 2020 Nov;22(5):4403-4411
miR‑155 modulates high glucose‑induced cardiac fibrosis via the Nrf2/HO‑1 signaling pathway.
Li Y, Duan JZ, He Q, Wang CQ
Molecular medicine reports 2020 Nov;22(5):4003-4016
Molecular medicine reports 2020 Nov;22(5):4003-4016
The AKT inhibitor MK2206 suppresses airway inflammation and the pro‑remodeling pathway in a TDI‑induced asthma mouse model.
Cui H, Cheng Y, He Y, Cheng W, Zhao W, Zhao H, Zhou FH, Wang L, Dong J, Cai S
Molecular medicine reports 2020 Nov;22(5):3723-3734
Molecular medicine reports 2020 Nov;22(5):3723-3734
LncRNA GAS5 inhibits NLRP3 inflammasome activation-mediated pyroptosis in diabetic cardiomyopathy by targeting miR-34b-3p/AHR.
Xu Y, Fang H, Xu Q, Xu C, Yang L, Huang C
Cell cycle (Georgetown, Tex.) 2020 Nov;19(22):3054-3065
Cell cycle (Georgetown, Tex.) 2020 Nov;19(22):3054-3065
Crosstalk between pleural mesothelial cell and lung fibroblast contributes to pulmonary fibrosis.
Liu F, Yu F, Lu YZ, Cheng PP, Liang LM, Wang M, Chen SJ, Huang Y, Song LJ, He XL, Xiong L, Xin JB, Ma WL, Ye H
Biochimica et biophysica acta. Molecular cell research 2020 Nov;1867(11):118806
Biochimica et biophysica acta. Molecular cell research 2020 Nov;1867(11):118806
Paired associated magnetic stimulation promotes neural repair in the rat middle cerebral artery occlusion model of stroke.
Gao BY, Sun CC, Xia GH, Zhou ST, Zhang Y, Mao YR, Liu PL, Zheng Y, Zhao D, Li XT, Xu J, Xu DS, Bai YL
Neural regeneration research 2020 Nov;15(11):2047-2056
Neural regeneration research 2020 Nov;15(11):2047-2056
TRAF6 Activates Fibroblasts to Cancer-Associated Fibroblasts through FGF19 in Tumor Microenvironment to Benefit the Malignant Phenotype of Melanoma Cells.
Guo Y, Zhang X, Zeng W, Zhang J, Cai L, Wu Z, Su J, Xiao Y, Liu N, Tang L, Xu X, Chen X, Peng C
The Journal of investigative dermatology 2020 Nov;140(11):2268-2279.e11
The Journal of investigative dermatology 2020 Nov;140(11):2268-2279.e11
Pomegranate flower extract bidirectionally regulates the proliferation, differentiation and apoptosis of 3T3-L1 cells through regulation of PPARγ expression mediated by PI3K-AKT signaling pathway.
Li T, Zhang L, Jin C, Xiong Y, Cheng YY, Chen K
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Nov;131:110769
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Nov;131:110769
Type 2 diabetes mellitus facilitates endometrial hyperplasia progression by activating the proliferative function of mucin O-glycosylating enzyme GALNT2.
Zhou X, Xu Y, Yin D, Zhao F, Hao Z, Zhong Y, Zhang J, Zhang B, Yin X
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Nov;131:110764
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Nov;131:110764
Indirubin alleviates bleomycin-induced pulmonary fibrosis in mice by suppressing fibroblast to myofibroblast differentiation.
Wang Q, Yu J, Hu Y, Chen X, Zhang L, Pan T, Miao K, Mou Y, Xu Y, Xiong W, Wang Y
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Nov;131:110715
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Nov;131:110715
Exosome secreted by human gingival fibroblasts in radiation therapy inhibits osteogenic differentiation of bone mesenchymal stem cells by transferring miR-23a.
Zhuang XM, Zhou B
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Nov;131:110672
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Nov;131:110672
The long noncoding RNA FTX promotes a malignant phenotype in bone marrow mesenchymal stem cells via the miR-186/c-Met axis.
Liu L, Li X, Shi Y, Chen H
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Nov;131:110666
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Nov;131:110666
Enhancement of anti-acne effect of Scutellaria baicalensis extract by fermentation with symbiotic fungus Penicillium decumbens.
Zhu X, Mao Y, Guo M, Yu H, Hao L, Hua Q, Lu Z, Hong M, An F
Journal of bioscience and bioengineering 2020 Nov;130(5):457-463
Journal of bioscience and bioengineering 2020 Nov;130(5):457-463
Nucleoredoxin interaction with flightless-I/actin complex is differentially altered in alcoholic liver disease.
Alarcón-Sánchez BR, Guerrero-Escalera D, Rosas-Madrigal S, Ivette Aparicio-Bautista D, Reyes-Gordillo K, Lakshman MR, Ortiz-Fernández A, Quezada H, Medina-Contreras Ó, Villa-Treviño S, Isael Pérez-Carreón J, Arellanes-Robledo J
Basic & clinical pharmacology & toxicology 2020 Nov;127(5):389-404
Basic & clinical pharmacology & toxicology 2020 Nov;127(5):389-404
NLRC3-like 1 inhibits NOD1-RIPK2 pathway via targeting RIPK2.
Fang H, Wu XM, Hu YW, Song YJ, Zhang J, Chang MX
Developmental and comparative immunology 2020 Nov;112:103769
Developmental and comparative immunology 2020 Nov;112:103769
TGF-β2 interfering oligonucleotides used as adjuvants for microbial vaccines.
Tu L, Sun X, Yang L, Zhang T, Zhang X, Li X, Dong B, Liu Y, Yang M, Wang L, Yu Y
Journal of leukocyte biology 2020 Nov;108(5):1673-1692
Journal of leukocyte biology 2020 Nov;108(5):1673-1692
Overexpression of Dnmt3a ameliorates diabetic muscle atrophy by modulating the Pten/Akt pathway.
Wang M, Wu X, Gan L, Teng Z, Zhang H, Zhang Y
Experimental physiology 2020 Nov;105(11):1918-1927
Experimental physiology 2020 Nov;105(11):1918-1927
Two resveratrol analogs, pinosylvin and 4,4'-dihydroxystilbene, improve oligoasthenospermia in a mouse model by attenuating oxidative stress via the Nrf2-ARE pathway.
Wang CN, Sang MM, Gong SN, Yang JF, Cheng CY, Sun F
Bioorganic chemistry 2020 Nov;104:104295
Bioorganic chemistry 2020 Nov;104:104295
MiR-124-3p promotes trophoblast cell HTR-8/SVneo pyroptosis by targeting placental growth factor.
Tao J, Xia LZ, Liang L, Chen Y, Wei D, Meng J, Wu S, Wang Z
Placenta 2020 Nov;101:176-184
Placenta 2020 Nov;101:176-184
MiR-185-5p ameliorates endoplasmic reticulum stress and renal fibrosis by downregulation of ATF6.
Yuan Q, Xu T, Chen Y, Qu W, Sun D, Liu X, Sun L
Laboratory investigation; a journal of technical methods and pathology 2020 Nov;100(11):1436-1446
Laboratory investigation; a journal of technical methods and pathology 2020 Nov;100(11):1436-1446
Cholestasis impairs hepatic lipid storage via AMPK and CREB signaling in hepatitis B virus surface protein transgenic mice.
Irungbam K, Roderfeld M, Glimm H, Hempel F, Schneider F, Hehr L, Glebe D, Churin Y, Morlock G, Yüce I, Roeb E
Laboratory investigation; a journal of technical methods and pathology 2020 Nov;100(11):1411-1424
Laboratory investigation; a journal of technical methods and pathology 2020 Nov;100(11):1411-1424
Inositol-Requiring Enzyme 1α Promotes Zika Virus Infection through Regulation of Stearoyl Coenzyme A Desaturase 1-Mediated Lipid Metabolism.
Huang Y, Lin Q, Huo Z, Chen C, Zhou S, Ma X, Gao H, Lin Y, Li X, He J, Zhang P, Liu C
Journal of virology 2020 Nov 9;94(23)
Journal of virology 2020 Nov 9;94(23)
Oroxylin A alleviates immunoparalysis of CLP mice by degrading CHOP through interacting with FBXO15.
Zhang Z, Wang Y, Shan Y, Zhou R, Yin W
Scientific reports 2020 Nov 6;10(1):19272
Scientific reports 2020 Nov 6;10(1):19272
Long-wave Ultraviolet Ray Promotes Inflammation in Keloid-derived Fibroblasts by Activating P38-NFκB1 Signaling Pathway.
Niu X, Lin X, Chen X, Xu S, Huang Z, Tang Q
Journal of burn care & research : official publication of the American Burn Association 2020 Nov 30;41(6):1231-1239
Journal of burn care & research : official publication of the American Burn Association 2020 Nov 30;41(6):1231-1239
Macrophage-derived small extracellular vesicles promote biomimetic mineralized collagen-mediated endogenous bone regeneration.
Liu A, Jin S, Fu C, Cui S, Zhang T, Zhu L, Wang Y, Shen SGF, Jiang N, Liu Y
International journal of oral science 2020 Nov 30;12(1):33
International journal of oral science 2020 Nov 30;12(1):33
miR-206 as a prognostic and sensitivity biomarker for platinum chemotherapy in epithelial ovarian cancer.
Yu X, Zhang X, Wang G, Wang B, Ding Y, Zhao J, Liu H, Cui S
Cancer cell international 2020 Nov 3;20(1):534
Cancer cell international 2020 Nov 3;20(1):534
Smyd3-PARP16 axis accelerates unfolded protein response and vascular aging.
Yang D, Wang Q, Wei G, Wu J, Zhu YC, Zhu Q, Ni T, Liu X, Zhu YZ
Aging 2020 Nov 3;12(21):21423-21445
Aging 2020 Nov 3;12(21):21423-21445
Grape Seed Proanthocyanidins Induce Apoptosis and Cell Cycle Arrest of HepG2 Cells Accompanied by Induction of the MAPK Pathway and NAG-1.
Wang L, Zhan J, Huang W
Antioxidants (Basel, Switzerland) 2020 Nov 28;9(12)
Antioxidants (Basel, Switzerland) 2020 Nov 28;9(12)
IQGAP3 interacts with Rad17 to recruit the Mre11-Rad50-Nbs1 complex and contributes to radioresistance in lung cancer.
Zeng Y, Jie X, Wu B, Wu G, Liu L, Xu S
Cancer letters 2020 Nov 28;493:254-265
Cancer letters 2020 Nov 28;493:254-265
Calnexin mediates the maturation of GPI-anchors through ER retention.
Guo XY, Liu YS, Gao XD, Kinoshita T, Fujita M
The Journal of biological chemistry 2020 Nov 27;295(48):16393-16410
The Journal of biological chemistry 2020 Nov 27;295(48):16393-16410
Catalysis of proline isomerization and molecular chaperone activity in a tug-of-war.
Favretto F, Flores D, Baker JD, Strohäker T, Andreas LB, Blair LJ, Becker S, Zweckstetter M
Nature communications 2020 Nov 27;11(1):6046
Nature communications 2020 Nov 27;11(1):6046
SAHA Overcomes 5-FU Resistance in IFIT2-Depleted Oral Squamous Cell Carcinoma Cells.
Regmi P, Lai KC, Liu CJ, Lee TC
Cancers 2020 Nov 26;12(12)
Cancers 2020 Nov 26;12(12)
Effect of conditioned medium from neural stem cells on glioma progression and its protein expression profile analysis.
Zhang GL, Qian C, Zhang SZ, Tuo YH, Zeng BY, Ji YX, Wang YZ
World journal of stem cells 2020 Nov 26;12(11):1396-1409
World journal of stem cells 2020 Nov 26;12(11):1396-1409
Legumain is a predictor of all-cause mortality and potential therapeutic target in acute myocardial infarction.
Yang H, He Y, Zou P, Hu Y, Li X, Tang L, Zhu Z, Tai S, Tu T, Xiao Y, Chen M, Wu C, Zhou S
Cell death & disease 2020 Nov 26;11(11):1014
Cell death & disease 2020 Nov 26;11(11):1014
Protective Effects of Fucoxanthin on High Glucose- and 4-Hydroxynonenal (4-HNE)-Induced Injury in Human Retinal Pigment Epithelial Cells.
Chiang YF, Chen HY, Chang YJ, Shih YH, Shieh TM, Wang KL, Hsia SM
Antioxidants (Basel, Switzerland) 2020 Nov 25;9(12)
Antioxidants (Basel, Switzerland) 2020 Nov 25;9(12)
The effect of whey protein on viral infection and replication of SARS-CoV-2 and pangolin coronavirus in vitro.
Fan H, Hong B, Luo Y, Peng Q, Wang L, Jin X, Chen Y, Hu Y, Shi Y, Li T, Zhuang H, Zhou YH, Tong Y, Xiang K
Signal transduction and targeted therapy 2020 Nov 24;5(1):275
Signal transduction and targeted therapy 2020 Nov 24;5(1):275
Two novel likely pathogenic variants of HARS2 identified in a Chinese family with sensorineural hearing loss.
Yu J, Jiang W, Cao L, Na X, Yang J
Hereditas 2020 Nov 24;157(1):47
Hereditas 2020 Nov 24;157(1):47
Loss of Atg7 causes chaotic nucleosome assembly of mouse bone marrow CD11b(+)Ly6G(-) myeloid cells.
Fang Y, Gu Y, Li L, Zhu L, Qian J, Zhao C, Xu L, Wei W, Du Y, Yuan N, Zhang S, Yuan Y, Xu Y, Jiang C, Wang J
Aging 2020 Nov 24;12(24):25673-25683
Aging 2020 Nov 24;12(24):25673-25683
RNAi-mediated silencing of Trichinella spiralis serpin-type serine protease inhibitors results in a reduction in larval infectivity.
Yi N, Yu P, Wu L, Liu Z, Guan J, Liu C, Liu M, Lu Y
Veterinary research 2020 Nov 23;51(1):139
Veterinary research 2020 Nov 23;51(1):139
Calcium and TRPV4 promote metastasis by regulating cytoskeleton through the RhoA/ROCK1 pathway in endometrial cancer.
Li X, Cheng Y, Wang Z, Zhou J, Jia Y, He X, Zhao L, Dong Y, Fan Y, Yang X, Shen B, Wu X, Wang J, Xiong C, Wei L, Li X, Wang J
Cell death & disease 2020 Nov 23;11(11):1009
Cell death & disease 2020 Nov 23;11(11):1009
TDP-43 interacts with amyloid-β, inhibits fibrillization, and worsens pathology in a model of Alzheimer's disease.
Shih YH, Tu LH, Chang TY, Ganesan K, Chang WW, Chang PS, Fang YS, Lin YT, Jin LW, Chen YR
Nature communications 2020 Nov 23;11(1):5950
Nature communications 2020 Nov 23;11(1):5950
MiR-103a-3p promotes tumour glycolysis in colorectal cancer via hippo/YAP1/HIF1A axis.
Sun Z, Zhang Q, Yuan W, Li X, Chen C, Guo Y, Shao B, Dang Q, Zhou Q, Wang Q, Wang G, Liu J, Kan Q
Journal of experimental & clinical cancer research : CR 2020 Nov 20;39(1):250
Journal of experimental & clinical cancer research : CR 2020 Nov 20;39(1):250
Inhibition of ferroptosis alleviates atherosclerosis through attenuating lipid peroxidation and endothelial dysfunction in mouse aortic endothelial cell.
Bai T, Li M, Liu Y, Qiao Z, Wang Z
Free radical biology & medicine 2020 Nov 20;160:92-102
Free radical biology & medicine 2020 Nov 20;160:92-102
Velvet antler polypeptide prevents the disruption of hepatic tight junctions via inhibiting oxidative stress in cholestatic mice and liver cell lines.
Li L, Yang F, Jia R, Yan P, Ma L
Food & function 2020 Nov 18;11(11):9752-9763
Food & function 2020 Nov 18;11(11):9752-9763
Loss of TDP-43 in astrocytes leads to motor deficits by triggering A1-like reactive phenotype and triglial dysfunction.
Peng AYT, Agrawal I, Ho WY, Yen YC, Pinter AJ, Liu J, Phua QXC, Koh KB, Chang JC, Sanford E, Man JHK, Wong P, Gutmann DH, Tucker-Kellogg G, Ling SC
Proceedings of the National Academy of Sciences of the United States of America 2020 Nov 17;117(46):29101-29112
Proceedings of the National Academy of Sciences of the United States of America 2020 Nov 17;117(46):29101-29112
The TLR3/IRF1/Type III IFN Axis Facilitates Antiviral Responses against Enterovirus Infections in the Intestine.
Su R, Shereen MA, Zeng X, Liang Y, Li W, Ruan Z, Li Y, Liu W, Liu Y, Wu K, Luo Z, Wu J
mBio 2020 Nov 17;11(6)
mBio 2020 Nov 17;11(6)
Urocortin participates in LPS-induced apoptosis of THP-1 macrophages via S1P-cPLA2 signaling pathway.
Zhu C, Zhou J, Li T, Mu J, Jin L, Li S
European journal of pharmacology 2020 Nov 15;887:173559
European journal of pharmacology 2020 Nov 15;887:173559
Identification and functional analysis of fourteen NR5A1 variants in patients with the 46 XY disorders of sex development.
Na X, Mao Y, Tang Y, Jiang W, Yu J, Cao L, Yang J
Gene 2020 Nov 15;760:145004
Gene 2020 Nov 15;760:145004
Inhibiting Rab27a in renal tubular epithelial cells attenuates the inflammation of diabetic kidney disease through the miR-26a-5p/CHAC1/NF-kB pathway.
Li S, Jia Y, Xue M, Hu F, Zheng Z, Zhang S, Ren S, Yang Y, Si Z, Wang L, Guan M, Xue Y
Life sciences 2020 Nov 15;261:118347
Life sciences 2020 Nov 15;261:118347
USP33 regulates c-Met expression by deubiquitinating SP1 to facilitate metastasis in hepatocellular carcinoma.
Gan Q, Shao J, Cao Y, Lei J, Xie P, Ge J, Hu G
Life sciences 2020 Nov 15;261:118316
Life sciences 2020 Nov 15;261:118316
Macrophage-Derived IL-1β Regulates Emergency Myelopoiesis via the NF-κB and C/ebpβ in Zebrafish.
Wei Z, Li C, Zhang Y, Lin C, Zhang Y, Shu L, Luo L, Zhuo J, Li L
Journal of immunology (Baltimore, Md. : 1950) 2020 Nov 15;205(10):2694-2706
Journal of immunology (Baltimore, Md. : 1950) 2020 Nov 15;205(10):2694-2706
Targeting HMGB3/hTERT axis for radioresistance in cervical cancer.
Li Z, Zhang Y, Sui S, Hua Y, Zhao A, Tian X, Wang R, Guo W, Yu W, Zou K, Deng W, He L, Zou L
Journal of experimental & clinical cancer research : CR 2020 Nov 13;39(1):243
Journal of experimental & clinical cancer research : CR 2020 Nov 13;39(1):243
Autophagic blockage by bismuth sulfide nanoparticles inhibits migration and invasion of HepG2 cells.
Hao BM, Liu YN, Zhang CY, Li GQ, Wang WN, Xu WD, Zha ZB, Wang F, Li C, Miao ZH, Yang XX, Chen YL, Qian HS, Zhou W
Nanotechnology 2020 Nov 13;31(46):465102
Nanotechnology 2020 Nov 13;31(46):465102
The role of macrophage migration inhibitory factor in promoting benign prostatic hyperplasia epithelial cell growth by modulating COX-2 and P53 signaling.
Song H, Shen Q, Hu S, Jin J
Biology open 2020 Nov 12;9(11)
Biology open 2020 Nov 12;9(11)
Electroacupuncture alleviates Parkinson disease and regulates the expression of brain-gut peptides.
Yu J, Min D, Bai Y, Qu L, Zou T, Wang S
Experimental animals 2020 Nov 12;69(4):448-460
Experimental animals 2020 Nov 12;69(4):448-460
Tomatidine inhibits porcine epidemic diarrhea virus replication by targeting 3CL protease.
Wang P, Bai J, Liu X, Wang M, Wang X, Jiang P
Veterinary research 2020 Nov 11;51(1):136
Veterinary research 2020 Nov 11;51(1):136
A CRISPR-Cas9 screen identifies mitochondrial translation as an essential process in latent KSHV infection of human endothelial cells.
Holmes DL, Vogt DT, Lagunoff M
Proceedings of the National Academy of Sciences of the United States of America 2020 Nov 10;117(45):28384-28392
Proceedings of the National Academy of Sciences of the United States of America 2020 Nov 10;117(45):28384-28392
Inhibition of notch enhances the anti-atherosclerotic effects of LXR agonists while reducing fatty liver development in ApoE-deficient mice.
Hao Y, Wang X, Zhang F, Wang M, Wang Y, Wang H, Du Y, Wang T, Fu F, Gao Z, Zhang L
Toxicology and applied pharmacology 2020 Nov 1;406:115211
Toxicology and applied pharmacology 2020 Nov 1;406:115211
Discovery of novel anti-angiogenesis agents. Part 11: Development of PROTACs based on active molecules with potency of promoting vascular normalization.
Shan Y, Si R, Wang J, Zhang Q, Li J, Ma Y, Zhang J
European journal of medicinal chemistry 2020 Nov 1;205:112654
European journal of medicinal chemistry 2020 Nov 1;205:112654
L-lactate preconditioning promotes plasticity-related proteins expression and reduces neurological deficits by potentiating GPR81 signaling in rat traumatic brain injury model.
Zhai X, Li J, Li L, Sun Y, Zhang X, Xue Y, Lv J, Gao Y, Li S, Yan W, Yin S, Xiao Z
Brain research 2020 Nov 1;1746:146945
Brain research 2020 Nov 1;1746:146945
Circ-PGAM1 promotes malignant progression of epithelial ovarian cancer through regulation of the miR-542-3p/CDC5L/PEAK1 pathway.
Zhang C, Li Y, Zhao W, Liu G, Yang Q
Cancer medicine 2020 May;9(10):3500-3521
Cancer medicine 2020 May;9(10):3500-3521
Inhibition of miR-103a-3p suppresses the proliferation in oral squamous cell carcinoma cells via targeting RCAN1.
Zhang G, Chen Z, Zhang Y, Li T, Bao Y, Zhang S
Neoplasma 2020 May;67(3):461-472
Neoplasma 2020 May;67(3):461-472
Grape Extract Activates Brown Adipose Tissue Through Pathway Involving the Regulation of Gut Microbiota and Bile Acid.
Han X, Guo J, Yin M, Liu Y, You Y, Zhan J, Huang W
Molecular nutrition & food research 2020 May;64(10):e2000149
Molecular nutrition & food research 2020 May;64(10):e2000149
Lysyl-tRNA synthetase produces diadenosine tetraphosphate to curb STING-dependent inflammation.
Guerra J, Valadao AL, Vlachakis D, Polak K, Vila IK, Taffoni C, Prabakaran T, Marriott AS, Kaczmarek R, Houel A, Auzemery B, Déjardin S, Boudinot P, Nawrot B, Jones NJ, Paludan SR, Kossida S, Langevin C, Laguette N
Science advances 2020 May;6(21):eaax3333
Science advances 2020 May;6(21):eaax3333
CtBP1 transactivates RAD51 and confers cisplatin resistance to breast cancer cells.
Deng Y, Guo W, Xu N, Li F, Li J
Molecular carcinogenesis 2020 May;59(5):512-519
Molecular carcinogenesis 2020 May;59(5):512-519
TRIM22 inhibits endometrial cancer progression through the NOD2/NF‑κB signaling pathway and confers a favorable prognosis.
Zhang L, Zhang B, Wei M, Xu Z, Kong W, Deng K, Xu X, Zhang L, Ζhao X, Yan L
International journal of oncology 2020 May;56(5):1225-1239
International journal of oncology 2020 May;56(5):1225-1239
Mechanism of aberrant long non-coding RNA expression in an adriamycin-resistant liver cancer cell strain.
Wang Y, Wan G, Wang H, Zhang G, Li Z, Lu L, Wu Y, Yu X, Du J
Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 2020 May;52(5):582-587
Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 2020 May;52(5):582-587
MicroRNA‑145‑5p inhibits osteosarcoma cell proliferation by targeting E2F transcription factor 3.
Li H, Pan R, Lu Q, Ren C, Sun J, Wu H, Wen J, Chen H
International journal of molecular medicine 2020 May;45(5):1317-1326
International journal of molecular medicine 2020 May;45(5):1317-1326
DNA methylation‑regulated miR‑155‑5p depresses sensitivity of esophageal carcinoma cells to radiation and multiple chemotherapeutic drugs via suppression of MAP3K10.
Luo W, Zhang H, Liang X, Xia R, Deng H, Yi Q, Lv L, Qian L
Oncology reports 2020 May;43(5):1692-1704
Oncology reports 2020 May;43(5):1692-1704
Ganoderic acid hinders renal fibrosis via suppressing the TGF-β/Smad and MAPK signaling pathways.
Geng XQ, Ma A, He JZ, Wang L, Jia YL, Shao GY, Li M, Zhou H, Lin SQ, Ran JH, Yang BX
Acta pharmacologica Sinica 2020 May;41(5):670-677
Acta pharmacologica Sinica 2020 May;41(5):670-677
PBX1 promotes development of natural killer cells by binding directly to the Nfil3 promoter.
Xu X, Zhou Y, Fu B, Zhang J, Dong Z, Zhang X, Shen N, Sun R, Tian Z, Wei H
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 May;34(5):6479-6492
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 May;34(5):6479-6492
Cognitive improvement and synaptic deficit attenuation by a multifunctional carbazole-based cyanine in AD mice model through regulation of Ca(2+)/CaMKII/CREB signaling pathway.
Chen C, Xu D, Zhang ZH, Jia SZ, Cao XC, Chen YB, Song GL, Wong MS, Li HW
Experimental neurology 2020 May;327:113210
Experimental neurology 2020 May;327:113210
Yeast β-D-glucan exerts antitumour activity in liver cancer through impairing autophagy and lysosomal function, promoting reactive oxygen species production and apoptosis.
Wang N, Liu H, Liu G, Li M, He X, Yin C, Tu Q, Shen X, Bai W, Wang Q, Tao Y, Yin H
Redox biology 2020 May;32:101495
Redox biology 2020 May;32:101495
BMX activates Wnt/β-catenin signaling pathway to promote cell proliferation and migration in breast cancer.
Li K, Pan WT, Ma YB, Xu XL, Gao Y, He YQ, Wei L, Zhang JW
Breast cancer (Tokyo, Japan) 2020 May;27(3):363-371
Breast cancer (Tokyo, Japan) 2020 May;27(3):363-371
Autophagy related 4B, upregulated by HIF-1α, attenuates the sensitivity to cisplatin in nasopharyngeal carcinoma cells.
Huang J, Li HB, Yu S, Yuan F, Lou ZP
European review for medical and pharmacological sciences 2020 May;24(9):4793-4802
European review for medical and pharmacological sciences 2020 May;24(9):4793-4802
LncRNA ZEB2-AS1 promotes the proliferation, migration and invasion of esophageal squamous cell carcinoma cell through miR-574-3p/HMGA2 axis.
Xu JH, Chen RZ, Liu LY, Li XM, Wu CP, Zhou YT, Yan JD, Zhang ZY
European review for medical and pharmacological sciences 2020 May;24(10):5391-5403
European review for medical and pharmacological sciences 2020 May;24(10):5391-5403
miR-181a/b-5p ameliorates inflammatory response in monocrotaline-induced pulmonary arterial hypertension by targeting endocan.
Zhao H, Guo Y, Sun Y, Zhang N, Wang X
Journal of cellular physiology 2020 May;235(5):4422-4433
Journal of cellular physiology 2020 May;235(5):4422-4433
Altered circadian clock as a novel therapeutic target for constant darkness-induced insulin resistance and hyperandrogenism of polycystic ovary syndrome.
Li S, Zhai J, Chu W, Geng X, Chen ZJ, Du Y
Translational research : the journal of laboratory and clinical medicine 2020 May;219:13-29
Translational research : the journal of laboratory and clinical medicine 2020 May;219:13-29
Mitophagy is involved in chromium (VI)-induced mitochondria damage in DF-1 cells.
Xu Y, Wang X, Geng N, Zhu Y, Zhang S, Liu Y, Liu J
Ecotoxicology and environmental safety 2020 May;194:110414
Ecotoxicology and environmental safety 2020 May;194:110414
Chlorogenic acid rescues zearalenone induced injury to mouse ovarian granulosa cells.
Yi Y, Wan S, Hou Y, Cheng J, Guo J, Wang S, Khan A, Sun N, Li H
Ecotoxicology and environmental safety 2020 May;194:110401
Ecotoxicology and environmental safety 2020 May;194:110401
SOX9 represses hepatitis B virus replication through binding to HBV EnhII/Cp and inhibiting the promoter activity.
Yang H, Zhou Y, Mo J, Xiang Q, Qin M, Liu W, Shang J, Yang Q, Xu W, Yang G, Tan Q, Wu K, Liu Y, Wu J
Antiviral research 2020 May;177:104761
Antiviral research 2020 May;177:104761
Modulation of NR1 receptor by CaMKIIα plays an important role in chronic itch development in mice.
Li NQ, Tang Y, Huang ST, Liu XT, Zeng LP, Li H, Wan L
Brain research bulletin 2020 May;158:66-76
Brain research bulletin 2020 May;158:66-76
RIP3/MLKL-mediated neuronal necroptosis induced by methamphetamine at 39°C.
Guo LM, Wang Z, Li SP, Wang M, Yan WT, Liu FX, Wang CD, Zhang XD, Chen D, Yan J, Xiong K
Neural regeneration research 2020 May;15(5):865-874
Neural regeneration research 2020 May;15(5):865-874
Activation of sirtuin1 protects against ischemia/reperfusion-induced acute kidney injury.
Gong L, He J, Sun X, Li L, Zhang X, Gan H
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 May;125:110021
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 May;125:110021
The natural compound andrographolide inhibits human aortic valve interstitial cell calcification via the NF-kappa B/Akt/ERK pathway.
Huang Y, Zhou X, Liu M, Zhou T, Shi J, Dong N, Xu K
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 May;125:109985
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 May;125:109985
Melanoma suppression by quercein is correlated with RIG-I and type I interferon signaling.
Peng D, Chen L, Sun Y, Sun L, Yin Q, Deng S, Niu L, Lou F, Wang Z, Xu Z, Wang C, Fan L, Wang H, Wang H
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 May;125:109984
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 May;125:109984
Silencing METTL3 inhibits the proliferation and invasion of osteosarcoma by regulating ATAD2.
Zhou L, Yang C, Zhang N, Zhang X, Zhao T, Yu J
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 May;125:109964
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 May;125:109964
ALDH1A1 maintains the cancer stem-like cells properties of esophageal squamous cell carcinoma by activating the AKT signal pathway and interacting with β-catenin.
Wang W, He S, Zhang R, Peng J, Guo D, Zhang J, Xiang B, Li L
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 May;125:109940
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 May;125:109940
Upregulation of nuclear factor (erythroid-derived 2)-like 2 protein level in the human colorectal adenocarcinoma cell line DLD-1 by a heterocyclic organobismuth(III) compound: Effect of organobismuth(III) compound on NRF2 signaling.
Iuchi K, Tasaki Y, Shirai S, Hisatomi H
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 May;125:109928
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 May;125:109928
KIF2A promotes the progression via AKT signaling pathway and is upregulated by transcription factor ETV4 in human gastric cancer.
Zhang X, Wang Y, Liu X, Zhao A, Yang Z, Kong F, Sun L, Yu Y, Jiang L
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 May;125:109840
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 May;125:109840
β-elemene suppresses the malignant behavior of esophageal cancer cells by regulating the phosphorylation of AKT.
Liang Y, Li S, Zheng G, Zhang L
Acta histochemica 2020 May;122(4):151538
Acta histochemica 2020 May;122(4):151538
DACT2 regulates structural and electrical atrial remodeling in atrial fibrillation.
Hou J, Huang S, Long Y, Huang J, Yang S, Yao J, Chen G, Yue Y, Liang M, Mei B, Li J, Wu Z
Journal of thoracic disease 2020 May;12(5):2039-2048
Journal of thoracic disease 2020 May;12(5):2039-2048
Protein kinase CK2 participates in estrogen-mediated endothelial progenitor cell homing to endometriotic lesions through stromal cells in a stromal cell-derived factor-1- CXCR4-dependent manner.
Zhao R, Feng D, Zhuang G, Liu Y, Chi S, Zhang J, Zhou X, Zhang W, Wang H
Fertility and sterility 2020 May;113(5):1067-1079.e5
Fertility and sterility 2020 May;113(5):1067-1079.e5
BMP8A promotes survival and drug resistance via Nrf2/TRIM24 signaling pathway in clear cell renal cell carcinoma.
Yu YP, Cai LC, Wang XY, Cheng SY, Zhang DM, Jian WG, Wang TD, Yang JK, Yang KB, Zhang C
Cancer science 2020 May;111(5):1555-1566
Cancer science 2020 May;111(5):1555-1566
Epithelial V-like antigen 1 promotes hepatocellular carcinoma growth and metastasis via the ERBB-PI3K-AKT pathway.
Ni Q, Chen Z, Zheng Q, Xie D, Li JJ, Cheng S, Ma X
Cancer science 2020 May;111(5):1500-1513
Cancer science 2020 May;111(5):1500-1513
Hydrogen inhibits the osteoclastogenesis of mouse bone marrow mononuclear cells.
Liu Y, Wang DL, Huang YC, Wang TB, Zeng H
Materials science & engineering. C, Materials for biological applications 2020 May;110:110640
Materials science & engineering. C, Materials for biological applications 2020 May;110:110640
Whole transcriptome sequencing reveals dexmedetomidine-improves postoperative cognitive dysfunction in rats via modulating lncRNA.
Deng F, Cai L, Zhou B, Zhou Z, Xu G
3 Biotech 2020 May;10(5):202
3 Biotech 2020 May;10(5):202
Morphometric, Hemodynamic, and Multi-Omics Analyses in Heart Failure Rats with Preserved Ejection Fraction.
Zhang W, Zhang H, Yao W, Li L, Niu P, Huo Y, Tan W
International journal of molecular sciences 2020 May 9;21(9)
International journal of molecular sciences 2020 May 9;21(9)
Rapid Neutralization Testing System for Zika Virus Based on an Enzyme-Linked Immunospot Assay.
Li S, Zhao H, Yang H, Hou W, Cruz-Cosme R, Cao R, Chen C, Wang W, Xu L, Zhang J, Zhong W, Xia N, Tang Q, Cheng T
ACS infectious diseases 2020 May 8;6(5):811-819
ACS infectious diseases 2020 May 8;6(5):811-819
Perturbation of phosphoglycerate kinase 1 (PGK1) only marginally affects glycolysis in cancer cells.
Jin C, Zhu X, Wu H, Wang Y, Hu X
The Journal of biological chemistry 2020 May 8;295(19):6425-6446
The Journal of biological chemistry 2020 May 8;295(19):6425-6446
PHLDA2 regulates EMT and autophagy in colorectal cancer via the PI3K/AKT signaling pathway.
Ma Z, Lou S, Jiang Z
Aging 2020 May 8;12(9):7985-8000
Aging 2020 May 8;12(9):7985-8000
Analysis of the role of the interleukins in colon cancer.
Wei X, Zhang Y, Yang Z, Sha Y, Pan Y, Chen Y, Cai L
Biological research 2020 May 7;53(1):20
Biological research 2020 May 7;53(1):20
Neuropeptide Y1 receptor antagonist promotes osteoporosis and microdamage repair and enhances osteogenic differentiation of bone marrow stem cells via cAMP/PKA/CREB pathway.
Xie W, Li F, Han Y, Qin Y, Wang Y, Chi X, Xiao J, Li Z
Aging 2020 May 7;12(9):8120-8136
Aging 2020 May 7;12(9):8120-8136
Self-responsive co-delivery system for remodeling tumor intracellular microenvironment to promote PTEN-mediated anti-tumor therapy.
Wang Y, Wang R, Wu S, An J, Liang Y, Hou L, Zhang Z
Nanoscale 2020 May 7;12(17):9392-9403
Nanoscale 2020 May 7;12(17):9392-9403
Small-molecule inhibition of aging-associated chromosomal instability delays cellular senescence.
Barroso-Vilares M, Macedo JC, Reis M, Warren JD, Compton D, Logarinho E
EMBO reports 2020 May 6;21(5):e49248
EMBO reports 2020 May 6;21(5):e49248
Naringin inhibits autophagy mediated by PI3K-Akt-mTOR pathway to ameliorate endothelial cell dysfunction induced by high glucose/high fat stress.
Wang K, Peng S, Xiong S, Niu A, Xia M, Xiong X, Zeng G, Huang Q
European journal of pharmacology 2020 May 5;874:173003
European journal of pharmacology 2020 May 5;874:173003
Downregulation of GLYR1 contributes to microsatellite instability colorectal cancer by targeting p21 via the p38MAPK and PI3K/AKT pathways.
Hu Z, Long T, Ma Y, Zhu J, Gao L, Zhong Y, Wang X, Wang X, Li Z
Journal of experimental & clinical cancer research : CR 2020 May 5;39(1):76
Journal of experimental & clinical cancer research : CR 2020 May 5;39(1):76
Kalirin Interacts with TRAPP and Regulates Rab11 and Endosomal Recycling.
Wang X, Weng M, Ke Y, Sapp E, DiFiglia M, Li X
Cells 2020 May 4;9(5)
Cells 2020 May 4;9(5)
The heterocyclic compound Tempol inhibits the growth of cancer cells by interfering with glutamine metabolism.
Ye S, Xu P, Huang M, Chen X, Zeng S, Wang Q, Chen J, Li K, Gao W, Liu R, Liu J, Shao Y, Zhang H, Xu Y, Zhang Q, Zhong Z, Wei Z, Wang J, Hao B, Huang W, Liu Q
Cell death & disease 2020 May 4;11(5):312
Cell death & disease 2020 May 4;11(5):312
Prenatal bisphenol A exposure contributes to Tau pathology: Potential roles of CDK5/GSK3β/PP2A axis in BPA-induced neurotoxicity.
Xue J, Zhang L, Xie X, Gao Y, Jiang L, Wang J, Wang Y, Gao R, Yu J, Xiao H
Toxicology 2020 May 30;438:152442
Toxicology 2020 May 30;438:152442
Pharmacogenomic Analysis Reveals CCNA2 as a Predictive Biomarker of Sensitivity to Polo-Like Kinase I Inhibitor in Gastric Cancer.
Lee Y, Lee CE, Oh S, Kim H, Lee J, Kim SB, Kim HS
Cancers 2020 May 30;12(6)
Cancers 2020 May 30;12(6)
Design, Synthesis, and Biological Evaluation of HSP90 Inhibitor-SN38 Conjugates for Targeted Drug Accumulation.
Zhu S, Shen Q, Gao Y, Wang L, Fang Y, Chen Y, Lu W
Journal of medicinal chemistry 2020 May 28;63(10):5421-5441
Journal of medicinal chemistry 2020 May 28;63(10):5421-5441
PAX6 contributes to the activation and proliferation of hepatic stellate cells via activating Hedgehog/GLI1 pathway.
Li C, Tan YH, Sun J, Deng FM, Liu YL
Biochemical and biophysical research communications 2020 May 28;526(2):314-320
Biochemical and biophysical research communications 2020 May 28;526(2):314-320
Synergistic antifibrotic effects of miR-451 with miR-185 partly by co-targeting EphB2 on hepatic stellate cells.
Chen X, Zhang D, Wang Y, Chen K, Zhao L, Xu Y, Jiang H, Wang S
Cell death & disease 2020 May 28;11(5):402
Cell death & disease 2020 May 28;11(5):402
Glycolytic and lipid oxidative metabolic programs are essential for freshly-isolated regulatory T cells in mice with sepsis.
Zhu X, Ji W, Guo S, Zhu D, Yang Y, Liu X
RSC advances 2020 May 27;10(35):21000-21008
RSC advances 2020 May 27;10(35):21000-21008
circStrn3 is involved in bone cancer pain regulation in a rat model.
Zhang Y, Zhang X, Xing Z, Tang S, Chen H, Zhang Z, Li J, Li Y
Acta biochimica et biophysica Sinica 2020 May 26;52(5):495-505
Acta biochimica et biophysica Sinica 2020 May 26;52(5):495-505
Circular RNA circNRIP1 promotes migration and invasion in cervical cancer by sponging miR-629-3p and regulating the PTP4A1/ERK1/2 pathway.
Li X, Ma N, Zhang Y, Wei H, Zhang H, Pang X, Li X, Wu D, Wang D, Yang Z, Zhang S
Cell death & disease 2020 May 26;11(5):399
Cell death & disease 2020 May 26;11(5):399
Evodiamine via targeting nNOS and AMPA receptor GluA1 inhibits nitroglycerin-induced migraine-like response.
Lin J, Zhang X, Li C, Zhang Y, Lu H, Chen J, Li Z, Yang X, Wu Z
Journal of ethnopharmacology 2020 May 23;254:112727
Journal of ethnopharmacology 2020 May 23;254:112727
Delivery of oligonucleotides to bone marrow to modulate ferrochelatase splicing in a mouse model of erythropoietic protoporphyria.
Halloy F, Iyer PS, Ćwiek P, Ghidini A, Barman-Aksözen J, Wildner-Verhey van Wijk N, Theocharides APA, Minder EI, Schneider-Yin X, Schümperli D, Hall J
Nucleic acids research 2020 May 21;48(9):4658-4671
Nucleic acids research 2020 May 21;48(9):4658-4671
Exogenous Therapeutics of Microrna-29a Attenuates Development of Hepatic Fibrosis in Cholestatic Animal Model through Regulation of Phosphoinositide 3-Kinase p85 Alpha.
Yang YL, Wang FS, Lin HY, Huang YH
International journal of molecular sciences 2020 May 21;21(10)
International journal of molecular sciences 2020 May 21;21(10)
KMT2A regulates cervical cancer cell growth through targeting VDAC1.
Zhang C, Hua Y, Qiu H, Liu T, Long Q, Liao W, Qiu J, Wang N, Chen M, Shi D, Yan Y, Xie C, Deng W, Li T, Li Y
Aging 2020 May 21;12(10):9604-9620
Aging 2020 May 21;12(10):9604-9620
Inhibition of protein phosphatase methylesterase 1 dysregulates MAP kinase signaling and attenuates muscle cell differentiation.
Labuzan SA, Lynch SA, Cooper LM, Waddell DS
Gene 2020 May 20;739:144515
Gene 2020 May 20;739:144515
Anti-inflammatory activity of berberine in non-alcoholic fatty liver disease via the Angptl2 pathway.
Lu Z, He B, Chen Z, Yan M, Wu L
BMC immunology 2020 May 19;21(1):28
BMC immunology 2020 May 19;21(1):28
Fatty Acid Synthase Inhibitor G28 Shows Anticancer Activity in EGFR Tyrosine Kinase Inhibitor Resistant Lung Adenocarcinoma Models.
Polonio-Alcalá E, Palomeras S, Torres-Oteros D, Relat J, Planas M, Feliu L, Ciurana J, Ruiz-Martínez S, Puig T
Cancers 2020 May 19;12(5)
Cancers 2020 May 19;12(5)
Bone-targeted lncRNA OGRU alleviates unloading-induced bone loss via miR-320-3p/Hoxa10 axis.
Wang K, Wang Y, Hu Z, Zhang L, Li G, Dang L, Tan Y, Cao X, Shi F, Zhang S, Zhang G
Cell death & disease 2020 May 19;11(5):382
Cell death & disease 2020 May 19;11(5):382
High-mobility group box 1 promotes epithelial-to-mesenchymal transition in crystalline silica induced pulmonary inflammation and fibrosis.
Ma J, Xu Y, Li W, Zhou Y, Wang D, Yang M, Wang B, Chen W
Toxicology letters 2020 May 17;330:134-143
Toxicology letters 2020 May 17;330:134-143
Knockdown of the Ribosomal Protein eL29 in Mammalian Cells Leads to Significant Changes in Gene Expression at the Transcription Level.
Gopanenko AV, Kolobova AV, Meschaninova MI, Venyaminova AG, Tupikin AE, Kabilov MR, Malygin AA, Karpova GG
Cells 2020 May 15;9(5)
Cells 2020 May 15;9(5)
TACC3 promotes prostate cancer cell proliferation and restrains primary cilium formation.
Qie Y, Wang L, Du E, Chen S, Lu C, Ding N, Yang K, Xu Y
Experimental cell research 2020 May 15;390(2):111952
Experimental cell research 2020 May 15;390(2):111952
Time serial transcriptome reveals Cyp2c29 as a key gene in hepatocellular carcinoma development.
Wang Q, Tang Q, Zhao L, Zhang Q, Wu Y, Hu H, Liu L, Liu X, Zhu Y, Guo A, Yang X
Cancer biology & medicine 2020 May 15;17(2):401-417
Cancer biology & medicine 2020 May 15;17(2):401-417
MEL endomorphins act as potent inflammatory analgesics with the inhibition of activated non-neuronal cells and modulation of pro-inflammatory cytokines.
Cui JM, Zhao L, Wang ZJ, Ma MT, Wang Y, Luo KY, Wang LQ, Wei S, Zhang XH, Han CZ, Liu X, Wang R
Neuropharmacology 2020 May 15;168:107992
Neuropharmacology 2020 May 15;168:107992
Heterogeneous nuclear ribonucleoprotein A3 controls mitotic progression of neural progenitors via interaction with cohesin.
Ou MY, Ju XC, Cai YJ, Sun XY, Wang JF, Fu XQ, Sun Q, Luo ZG
Development (Cambridge, England) 2020 May 15;147(10)
Development (Cambridge, England) 2020 May 15;147(10)
UBQLN2 Promotes the Production of Type I Interferon via the TBK1-IRF3 Pathway.
Chen T, Zhang W, Huang B, Chen X, Huang C
Cells 2020 May 13;9(5)
Cells 2020 May 13;9(5)
Membrane-Associated α-Tubulin Is Less Acetylated in Postmortem Prefrontal Cortex from Depressed Subjects Relative to Controls: Cytoskeletal Dynamics, HDAC6, and Depression.
Singh H, Chmura J, Bhaumik R, Pandey GN, Rasenick MM
The Journal of neuroscience : the official journal of the Society for Neuroscience 2020 May 13;40(20):4033-4041
The Journal of neuroscience : the official journal of the Society for Neuroscience 2020 May 13;40(20):4033-4041
Discovery of a novel third-generation EGFR inhibitor and identification of a potential combination strategy to overcome resistance.
Zhang T, Qu R, Chan S, Lai M, Tong L, Feng F, Chen H, Song T, Song P, Bai G, Liu Y, Wang Y, Li Y, Su Y, Shen Y, Sun Y, Chen Y, Geng M, Ding K, Ding J, Xie H
Molecular cancer 2020 May 13;19(1):90
Molecular cancer 2020 May 13;19(1):90
Evidence for Cytoprotective Effect of Carbon Monoxide Donor in the Development of Acute Esophagitis Leading to Acute Esophageal Epithelium Lesions.
Magierowska K, Bakalarz D, Wójcik D, Korbut E, Danielak A, Głowacka U, Pajdo R, Buszewicz G, Ginter G, Surmiak M, Kwiecień S, Chmura A, Magierowski M, Brzozowski T
Cells 2020 May 12;9(5)
Cells 2020 May 12;9(5)
EFEMP2 indicates assembly of M0 macrophage and more malignant phenotypes of glioma.
Huang L, Wang Z, Chang Y, Wang K, Kang X, Huang R, Zhang Y, Chen J, Zeng F, Wu F, Zhao Z, Li G, Huang H, Jiang T, Hu H
Aging 2020 May 12;12(9):8397-8412
Aging 2020 May 12;12(9):8397-8412
SETDB1 promotes the progression of colorectal cancer via epigenetically silencing p21 expression.
Cao N, Yu Y, Zhu H, Chen M, Chen P, Zhuo M, Mao Y, Li L, Zhao Q, Wu M, Ye M
Cell death & disease 2020 May 11;11(5):351
Cell death & disease 2020 May 11;11(5):351
POTEE promotes colorectal carcinoma progression via activating the Rac1/Cdc42 pathway.
Xu Q, Chen J, Peng M, Duan S, Hu Y, Guo D, Geng J, Zhou J
Experimental cell research 2020 May 1;390(1):111933
Experimental cell research 2020 May 1;390(1):111933
RNA-Seq Reveals Underlying Transcriptomic Mechanisms of Bone Marrow-Derived Mesenchymal Stem Cells in the Regulation of Microglia-Mediated Neuroinflammation After Subarachnoid Hemorrhage.
Zhang L, Guo K, Yin S, Peng J, Pang J, Ma N, Zhang X, Xie Y, Chen L, Jiang Y
Stem cells and development 2020 May 1;29(9):562-573
Stem cells and development 2020 May 1;29(9):562-573
Type 3 adenylyl cyclase in the main olfactory epithelium participates in depression-like and anxiety-like behaviours.
Liu X, Zhou Y, Li S, Yang D, Jiao M, Liu X, Wang Z
Journal of affective disorders 2020 May 1;268:28-38
Journal of affective disorders 2020 May 1;268:28-38
A modular biomimetic strategy for the synthesis of macrolide P-glycoprotein inhibitors via Rh-catalyzed C-H activation.
Chen L, Quan H, Xu Z, Wang H, Xia Y, Lou L, Yang W
Nature communications 2020 May 1;11(1):2151
Nature communications 2020 May 1;11(1):2151
Demethyleneberberine attenuates concanavalin A-induced autoimmune hepatitis in mice through inhibition of NF-κB and MAPK signaling.
Zhang M, Li Q, Zhou C, Zhao Y, Li R, Zhang Y
International immunopharmacology 2020 Mar;80:106137
International immunopharmacology 2020 Mar;80:106137
Downregulation of ubiquitin-specific protease 2 possesses prognostic and diagnostic value and promotes the clear cell renal cell carcinoma progression.
Meng X, Xiong Z, Xiao W, Yuan C, Wang C, Huang Y, Tong J, Shi J, Chen Z, Liu C, Xie K, Xiong H, Chen K, Yang H, Zhang X
Annals of translational medicine 2020 Mar;8(6):319
Annals of translational medicine 2020 Mar;8(6):319
Genome sequencing analysis of a family with a child displaying severe abdominal distention and recurrent hypoglycemia.
Liu J, Ding G, Zou K, Jiang Z, Zhang J, Lu Y, Pignata A, Venner E, Liu P, Liu Z, Wangler MF, Sun Z
Molecular genetics & genomic medicine 2020 Mar;8(3):e1130
Molecular genetics & genomic medicine 2020 Mar;8(3):e1130
Characterization of seminal plasma proteomic alterations associated with the IVF and rescue-ICSI pregnancy in assisted reproduction.
Liu X, Liu G, Zhu P, Wang Y, Wang J, Zhang W, Wang W, Li N, Wang X, Zhang C, Liu J, Shen X, Liu F
Andrology 2020 Mar;8(2):407-420
Andrology 2020 Mar;8(2):407-420
Mouse model of metformin-induced diarrhea.
Takemori H, Hamamoto A, Isogawa K, Ito M, Takagi M, Morino H, Miura T, Oshida K, Shibata T
BMJ open diabetes research & care 2020 Mar;8(1)
BMJ open diabetes research & care 2020 Mar;8(1)
Rosmarinic acid exerts an anticancer effect on osteosarcoma cells by inhibiting DJ-1 via regulation of the PTEN-PI3K-Akt signaling pathway.
Ma Z, Yang J, Yang Y, Wang X, Chen G, Shi A, Lu Y, Jia S, Kang X, Lu L
Phytomedicine : international journal of phytotherapy and phytopharmacology 2020 Mar;68:153186
Phytomedicine : international journal of phytotherapy and phytopharmacology 2020 Mar;68:153186
Elevated myocardial SORBS2 and the underlying implications in left ventricular noncompaction cardiomyopathy.
Li C, Liu F, Liu S, Pan H, Du H, Huang J, Xie Y, Li Y, Zhao R, Wei Y
EBioMedicine 2020 Mar;53:102695
EBioMedicine 2020 Mar;53:102695
Thymosinβ4 alleviates cholestatic liver fibrosis in mice through downregulating PDGF/PDGFR and TGFβ/Smad pathways.
Chen C, Li X, Wang L
Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 2020 Mar;52(3):324-330
Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 2020 Mar;52(3):324-330
MicroRNA‑137 suppresses the proliferation, migration and invasion of cholangiocarcinoma cells by targeting WNT2B.
Chen T, Lei S, Zeng Z, Pan S, Zhang J, Xue Y, Sun Y, Lan J, Xu S, Mao D, Guo B
International journal of molecular medicine 2020 Mar;45(3):886-896
International journal of molecular medicine 2020 Mar;45(3):886-896
Linc00261 inhibits metastasis and the WNT signaling pathway of pancreatic cancer by regulating a miR‑552‑5p/FOXO3 axis.
Chen T, Lei S, Zeng Z, Zhang J, Xue Y, Sun Y, Lan J, Xu S, Mao D, Guo B
Oncology reports 2020 Mar;43(3):930-942
Oncology reports 2020 Mar;43(3):930-942
Aurora B induces epithelial-mesenchymal transition by stabilizing Snail1 to promote basal-like breast cancer metastasis.
Zhang J, Lin X, Wu L, Huang JJ, Jiang WQ, Kipps TJ, Zhang S
Oncogene 2020 Mar;39(12):2550-2567
Oncogene 2020 Mar;39(12):2550-2567
The Wnt/β-catenin/VASP positive feedback loop drives cell proliferation and migration in breast cancer.
Li K, Zhang J, Tian Y, He Y, Xu X, Pan W, Gao Y, Chen F, Wei L
Oncogene 2020 Mar;39(11):2258-2274
Oncogene 2020 Mar;39(11):2258-2274
Dehydrocostus lactone inhibits NLRP3 inflammasome activation by blocking ASC oligomerization and prevents LPS-mediated inflammation in vivo.
Chen Y, Li R, Wang Z, Hou X, Wang C, Ai Y, Shi W, Zhan X, Wang JB, Xiao X, Bai Z, Sun H, Xu G
Cellular immunology 2020 Mar;349:104046
Cellular immunology 2020 Mar;349:104046
Identification of apoptosis-associated protein factors distinctly expressed in cigarette smoke condensate-exposed airway bronchial epithelial cells.
Lin BC, Li QY, Tian L, Liu HL, Liu XH, Shi Y, He C, Ding SS, Yan J, Li K, Bian LP, Lai WQ, Zhang W, Li X, Xi ZG
Journal of biochemical and molecular toxicology 2020 Mar;34(3):e22444
Journal of biochemical and molecular toxicology 2020 Mar;34(3):e22444
HUWE1 promotes EGFR ubiquitination and degradation to protect against renal tubulointerstitial fibrosis.
Zhu Q, Dong H, Bukhari AA, Zhao A, Li M, Sun Y, Zhang X, Cao C, Su D, Liang X
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Mar;34(3):4591-4601
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Mar;34(3):4591-4601
Upregulation of KSRP by miR-27b attenuates schistosomiasis-induced hepatic fibrosis by targeting TGF-β1.
Wang S, Li M, Zhao X, Wang H, Zhu J, Wang C, Zhou M, Dong H, Zhou R
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Mar;34(3):4120-4133
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Mar;34(3):4120-4133
Jmjd3 regulates inflammasome activation and aggravates DSS-induced colitis in mice.
Huang M, Wang Q, Long F, Di Y, Wang J, Zhun Zhu Y, Liu X
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Mar;34(3):4107-4119
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Mar;34(3):4107-4119
Inflammatory-sensitive CHI3L1 protects nucleus pulposus via AKT3 signaling during intervertebral disc degeneration.
Wang R, Xu C, Zhong H, Hu B, Wei L, Liu N, Zhang Y, Shi Q, Wang C, Qi M, Gu Y, Shen X, Tian Y, Liu Y, Cao P, Chen H, Yuan W
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Mar;34(3):3554-3569
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Mar;34(3):3554-3569
Do You Know the Details of Your PAX8 Antibody? Monoclonal PAX8 (MRQ-50) Is Not Expressed in a Series of 45 Medullary Thyroid Carcinomas.
Gucer H, Caliskan S, Kefeli M, Mete O
Endocrine pathology 2020 Mar;31(1):33-38
Endocrine pathology 2020 Mar;31(1):33-38
A serpin from the tick Rhipicephalus haemaphysaloides: Involvement in vitellogenesis.
Xu Z, Yan Y, Zhang H, Cao J, Zhou Y, Xu Q, Zhou J
Veterinary parasitology 2020 Mar;279:109064
Veterinary parasitology 2020 Mar;279:109064
Atlastin-1 modulates seizure activity and neuronal excitability.
Lu X, Yang M, Yang Y, Wang XF
CNS neuroscience & therapeutics 2020 Mar;26(3):385-393
CNS neuroscience & therapeutics 2020 Mar;26(3):385-393
Immunoproteasome subunit β5i regulates diet-induced atherosclerosis through altering MERTK-mediated efferocytosis in Apoe knockout mice.
Liao J, Xie Y, Lin Q, Yang X, An X, Xia Y, Du J, Wang F, Li HH
The Journal of pathology 2020 Mar;250(3):275-287
The Journal of pathology 2020 Mar;250(3):275-287
Rutin promotes osteogenic differentiation of periodontal ligament stem cells through the GPR30-mediated PI3K/AKT/mTOR signaling pathway.
Zhao B, Xiong Y, Zhang Y, Jia L, Zhang W, Xu X
Experimental biology and medicine (Maywood, N.J.) 2020 Mar;245(6):552-561
Experimental biology and medicine (Maywood, N.J.) 2020 Mar;245(6):552-561
Oxymatrine suppresses IL-1β-induced degradation of the nucleus pulposus cell and extracellular matrix through the TLR4/NF-κB signaling pathway.
Wei K, Dai J, Wang Z, Pei Y, Chen Y, Ding Y, Ding Q, Ahati P, Zhou X, Wang H, Fang H
Experimental biology and medicine (Maywood, N.J.) 2020 Mar;245(6):532-541
Experimental biology and medicine (Maywood, N.J.) 2020 Mar;245(6):532-541
Anti-ageing effects of red ginseng on female Drosophila melanogaster.
Hou W, Pei J, Wang Y, Zhang J, Zheng H, Cui R
Journal of cellular and molecular medicine 2020 Mar;24(6):3751-3755
Journal of cellular and molecular medicine 2020 Mar;24(6):3751-3755
MiR-133a alleviates renal injury caused by sepsis by targeting BNIP3L.
Qin LY, Wang MX, Zhang H
European review for medical and pharmacological sciences 2020 Mar;24(5):2632-2639
European review for medical and pharmacological sciences 2020 Mar;24(5):2632-2639
Dioscin inhibits the growth of human osteosarcoma by inducing G2/M-phase arrest, apoptosis, and GSDME-dependent cell death in vitro and in vivo.
Ding Q, Zhang W, Cheng C, Mo F, Chen L, Peng G, Cai X, Wang J, Yang S, Liu X
Journal of cellular physiology 2020 Mar;235(3):2911-2924
Journal of cellular physiology 2020 Mar;235(3):2911-2924
Autophagy inhibition via Becn1 downregulation improves the mesenchymal stem cells antifibrotic potential in experimental liver fibrosis.
Wang HY, Li C, Liu WH, Deng FM, Ma Y, Guo LN, Kong H, Hu KA, Liu Q, Wu J, Sun J, Liu YL
Journal of cellular physiology 2020 Mar;235(3):2722-2737
Journal of cellular physiology 2020 Mar;235(3):2722-2737
Decreasing New York esophageal squamous cell carcinoma 1 expression inhibits multiple myeloma growth and osteolytic lesions.
Li F, Zhao F, Li M, Pan M, Shi F, Xu H, Zheng D, Wang L, Dou J
Journal of cellular physiology 2020 Mar;235(3):2183-2194
Journal of cellular physiology 2020 Mar;235(3):2183-2194
Silencing of tumor-suppressive NR_023387 in renal cell carcinoma via promoter hypermethylation and HNF4A deficiency.
Zhou H, Guo L, Yao W, Shi R, Yu G, Xu H, Ye Z
Journal of cellular physiology 2020 Mar;235(3):2113-2128
Journal of cellular physiology 2020 Mar;235(3):2113-2128
Polystyrene nanoplastic induces ROS production and affects the MAPK-HIF-1/NFkB-mediated antioxidant system in Daphnia pulex.
Liu Z, Huang Y, Jiao Y, Chen Q, Wu D, Yu P, Li Y, Cai M, Zhao Y
Aquatic toxicology (Amsterdam, Netherlands) 2020 Mar;220:105420
Aquatic toxicology (Amsterdam, Netherlands) 2020 Mar;220:105420
The tacrolimus-induced glucose homeostasis imbalance in terms of the liver: From bench to bedside.
Ling Q, Huang H, Han Y, Zhang C, Zhang X, Chen K, Wu L, Tang R, Zheng Z, Zheng S, Li L, Wang B
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2020 Mar;20(3):701-713
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2020 Mar;20(3):701-713
miR-181a negatively modulates synaptic plasticity in hippocampal cultures and its inhibition rescues memory deficits in a mouse model of Alzheimer's disease.
Rodriguez-Ortiz CJ, Prieto GA, Martini AC, Forner S, Trujillo-Estrada L, LaFerla FM, Baglietto-Vargas D, Cotman CW, Kitazawa M
Aging cell 2020 Mar;19(3):e13118
Aging cell 2020 Mar;19(3):e13118
Ubiquitination of P53 by E3 ligase MKRN2 promotes melanoma cell proliferation.
Zhang Y, Cui N, Zheng G
Oncology letters 2020 Mar;19(3):1975-1984
Oncology letters 2020 Mar;19(3):1975-1984
MicroRNA-103a-3p potentiates chemoresistance to cisplatin in non-small cell lung carcinoma by targeting neurofibromatosis 1.
Zhu H, Yang J, Yang S
Experimental and therapeutic medicine 2020 Mar;19(3):1797-1805
Experimental and therapeutic medicine 2020 Mar;19(3):1797-1805
The functional role of the C-terminal tail of the human ribosomal protein uS19.
Bulygin K, Malygin A, Gopanenko A, Graifer D, Karpova G
Biochimica et biophysica acta. Gene regulatory mechanisms 2020 Mar;1863(3):194490
Biochimica et biophysica acta. Gene regulatory mechanisms 2020 Mar;1863(3):194490
A long noncoding RNA sensitizes genotoxic treatment by attenuating ATM activation and homologous recombination repair in cancers.
Zhao K, Wang X, Xue X, Li L, Hu Y
PLoS biology 2020 Mar;18(3):e3000666
PLoS biology 2020 Mar;18(3):e3000666
Hypericin attenuates nonalcoholic fatty liver disease and abnormal lipid metabolism via the PKA-mediated AMPK signaling pathway in vitro and in vivo.
Liang C, Li Y, Bai M, Huang Y, Yang H, Liu L, Wang S, Yu C, Song Z, Bao Y, Yi J, Sun L, Li Y
Pharmacological research 2020 Mar;153:104657
Pharmacological research 2020 Mar;153:104657
Synthesis of dual functional procaine-derived carbon dots for bioimaging and anticancer therapy.
Zhao X, Qi T, Yang M, Zhang W, Kong C, Hao M, Wang Y, Zhang H, Yang B, Yang J, Jiang J
Nanomedicine (London, England) 2020 Mar;15(7):677-689
Nanomedicine (London, England) 2020 Mar;15(7):677-689
Matrix mechanics and water permeation regulate extracellular vesicle transport.
Lenzini S, Bargi R, Chung G, Shin JW
Nature nanotechnology 2020 Mar;15(3):217-223
Nature nanotechnology 2020 Mar;15(3):217-223
A new abietane diterpenoid from Ajuga ovalifolia var. calantha induces human lung epithelial A549 cell apoptosis by inhibiting SHP2.
Liu DM, Cao ZX, Yan HL, Li W, Yang F, Zhao WJ, Diao QC, Tan YZ
Fitoterapia 2020 Mar;141:104484
Fitoterapia 2020 Mar;141:104484
LongShengZhi capsule inhibits doxorubicin-induced heart failure by anti-oxidative stress.
Xu S, Wang Y, Yu M, Wang D, Liang Y, Chen Y, Liao C, Xie Z, Zhao B, Han J, Duan Y, Yang X
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Mar;123:109803
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Mar;123:109803
DKC1 enhances angiogenesis by promoting HIF-1α transcription and facilitates metastasis in colorectal cancer.
Hou P, Shi P, Jiang T, Yin H, Chu S, Shi M, Bai J, Song J
British journal of cancer 2020 Mar;122(5):668-679
British journal of cancer 2020 Mar;122(5):668-679
IL1β inhibits differentiation of cementoblasts via microRNA-325-3p.
Wang Y, Li Y, Shao P, Wang L, Bao X, Hu M
Journal of cellular biochemistry 2020 Mar;121(3):2606-2617
Journal of cellular biochemistry 2020 Mar;121(3):2606-2617
G protein-coupled receptor kinase-2: A potential biomarker for early diabetic cardiomyopathy.
Lai S, Fu X, Yang S, Zhang S, Lin Q, Zhang M, Chen H
Journal of diabetes 2020 Mar;12(3):247-258
Journal of diabetes 2020 Mar;12(3):247-258
Cannabinoid receptor 1 knockout alleviates hepatic steatosis by downregulating perilipin 2.
Irungbam K, Churin Y, Matono T, Weglage J, Ocker M, Glebe D, Hardt M, Koeppel A, Roderfeld M, Roeb E
Laboratory investigation; a journal of technical methods and pathology 2020 Mar;100(3):454-465
Laboratory investigation; a journal of technical methods and pathology 2020 Mar;100(3):454-465
ETS2 promotes epithelial-to-mesenchymal transition in renal fibrosis by targeting JUNB transcription.
Yao F, Wang X, Cui ZK, Lan H, Ai X, Song Q, Chen Z, Yang J, Wu B, Bai X
Laboratory investigation; a journal of technical methods and pathology 2020 Mar;100(3):438-453
Laboratory investigation; a journal of technical methods and pathology 2020 Mar;100(3):438-453
MicroRNA-217-5p ameliorates endothelial cell apoptosis induced by ox-LDL by targeting CLIC4.
Zhang X, Wang Z, Li W, Huang R, Zheng D, Bi G
Nutrition, metabolism, and cardiovascular diseases : NMCD 2020 Mar 9;30(3):523-533
Nutrition, metabolism, and cardiovascular diseases : NMCD 2020 Mar 9;30(3):523-533
Melatonin Promotes the Proliferation of Chicken Sertoli Cells by Activating the ERK/Inhibin Alpha Subunit Signaling Pathway.
Xu K, Wang J, Liu H, Zhao J, Lu W
Molecules (Basel, Switzerland) 2020 Mar 9;25(5)
Molecules (Basel, Switzerland) 2020 Mar 9;25(5)
Molecular hydrogen attenuates methamphetamine-induced behavioral sensitization and activation of ERK-ΔFosB signaling in the mouse nucleus accumbens.
Wen D, Hui R, Liu Y, Luo Y, Wang J, Shen X, Xie B, Yu F, Cong B, Ma C
Progress in neuro-psychopharmacology & biological psychiatry 2020 Mar 8;97:109781
Progress in neuro-psychopharmacology & biological psychiatry 2020 Mar 8;97:109781
Topology, Antiviral Functional Residues and Mechanism of IFITM1.
Sun F, Xia Z, Han Y, Gao M, Wang L, Wu Y, Sabatier JM, Miao L, Cao Z
Viruses 2020 Mar 8;12(3)
Viruses 2020 Mar 8;12(3)
Novel HSP90-PI3K Dual Inhibitor Suppresses Melanoma Cell Proliferation by Interfering with HSP90-EGFR Interaction and Downstream Signaling Pathways.
Zhao Q, Zhu HP, Xie X, Mao Q, Liu YQ, He XH, Peng C, Jiang QL, Huang W
International journal of molecular sciences 2020 Mar 7;21(5)
International journal of molecular sciences 2020 Mar 7;21(5)
Transcription co-activator P300 activates Elk1-aPKC-ι signaling mediated epithelial-to-mesenchymal transition and malignancy in hepatocellular carcinoma.
Ma C, Huang S, Xu L, Tian L, Yang Y, Wang J
Oncogenesis 2020 Mar 6;9(3):32
Oncogenesis 2020 Mar 6;9(3):32
Anti-toll-like receptor 2 antibody ameliorates hepatic injury, inflammation, fibrosis and steatosis in obesity-related metabolic disorder rats via regulating MAPK and NF-κB pathways.
Wu L, Sun J, Liu L, Du X, Liu Y, Yan X, Kombo Osoro E, Zhang F, Feng L, Liang D, Li Y, Chen Q, Sun S, Zhang L, Lan X, Li D, Lu S
International immunopharmacology 2020 Mar 6;82:106368
International immunopharmacology 2020 Mar 6;82:106368
Pathway-specific enzymes from bamboo and crop leaves biosynthesize anti-nociceptive C-glycosylated flavones.
Sun Y, Chen Z, Yang J, Mutanda I, Li S, Zhang Q, Zhang Y, Zhang Y, Wang Y
Communications biology 2020 Mar 6;3(1):110
Communications biology 2020 Mar 6;3(1):110
Human polymorphisms in GSDMD alter the inflammatory response.
Rathkey JK, Xiao TS, Abbott DW
The Journal of biological chemistry 2020 Mar 6;295(10):3228-3238
The Journal of biological chemistry 2020 Mar 6;295(10):3228-3238
lncRNA RMST Suppressed GBM Cell Mitophagy through Enhancing FUS SUMOylation.
Liu C, Peng Z, Li P, Fu H, Feng J, Zhang Y, Liu T, Liu Y, Liu Q, Liu Q, Li D, Wu M
Molecular therapy. Nucleic acids 2020 Mar 6;19:1198-1208
Molecular therapy. Nucleic acids 2020 Mar 6;19:1198-1208
The 25(OH)D/VDR signaling may play a role in major depression.
He Y, Wu Z, Lan T, Wang Y, Tian Y, Chen X, Li Y, Bai M, Liu J, Gong X, Cheng K, Xie P
Biochemical and biophysical research communications 2020 Mar 5;523(2):405-410
Biochemical and biophysical research communications 2020 Mar 5;523(2):405-410
TRPC6-dependent Ca(2+) signaling mediates airway inflammation in response to oxidative stress via ERK pathway.
Chen Q, Zhou Y, Zhou L, Fu Z, Yang C, Zhao L, Li S, Chen Y, Wu Y, Ling Z, Wang Y, Huang J, Li J
Cell death & disease 2020 Mar 5;11(3):170
Cell death & disease 2020 Mar 5;11(3):170
PTEN inhibitor VO-OHpic attenuates GC-associated endothelial progenitor cell dysfunction and osteonecrosis of the femoral head via activating Nrf2 signaling and inhibiting mitochondrial apoptosis pathway.
Yao X, Yu S, Jing X, Guo J, Sun K, Guo F, Ye Y
Stem cell research & therapy 2020 Mar 30;11(1):140
Stem cell research & therapy 2020 Mar 30;11(1):140
Genetic inactivation of mTORC1 or mTORC2 in neurons reveals distinct functions in glutamatergic synaptic transmission.
McCabe MP, Cullen ER, Barrows CM, Shore AN, Tooke KI, Laprade KA, Stafford JM, Weston MC
eLife 2020 Mar 3;9
eLife 2020 Mar 3;9
5-HT(1A)R alleviates Aβ-induced cognitive decline and neuroinflammation through crosstalk with NF-κB pathway in mice.
Wang M, Zong HF, Chang KW, Han H, Yasir Rizvi M, Iffat Neha S, Li ZY, Yang WN, Qian YH
International immunopharmacology 2020 Mar 3;82:106354
International immunopharmacology 2020 Mar 3;82:106354
Nanofiber Alignment Mediates the Pattern of Single Cell Migration.
Wang Y, Yao Y
Langmuir : the ACS journal of surfaces and colloids 2020 Mar 3;36(8):2129-2135
Langmuir : the ACS journal of surfaces and colloids 2020 Mar 3;36(8):2129-2135
Qingyi decoction protects against myocardial injuries induced by severe acute pancreatitis.
Li L, Li YQ, Sun ZW, Xu CM, Wu J, Liu GL, Bakheet AM, Chen HL
World journal of gastroenterology 2020 Mar 28;26(12):1317-1328
World journal of gastroenterology 2020 Mar 28;26(12):1317-1328
The Agpat4/LPA axis in colorectal cancer cells regulates antitumor responses via p38/p65 signaling in macrophages.
Zhang D, Shi R, Xiang W, Kang X, Tang B, Li C, Gao L, Zhang X, Zhang L, Dai R, Miao H
Signal transduction and targeted therapy 2020 Mar 27;5(1):24
Signal transduction and targeted therapy 2020 Mar 27;5(1):24
Long non-coding RNA HAL suppresses the migration and invasion of serous ovarian cancer by inhibiting EMT signaling pathway.
Wu K, Li L, Li L, Wang D
Bioscience reports 2020 Mar 27;40(3)
Bioscience reports 2020 Mar 27;40(3)
Posttranslational lysine 2-hydroxyisobutyrylation of human sperm tail proteins affects motility.
Cheng YM, Peng Z, Chen HY, Pan TT, Hu XN, Wang F, Luo T
Human reproduction (Oxford, England) 2020 Mar 27;35(3):494-503
Human reproduction (Oxford, England) 2020 Mar 27;35(3):494-503
The C-terminal domain of feline and bovine SAMHD1 proteins has a crucial role in lentiviral restriction.
Wang C, Zhang K, Meng L, Zhang X, Song Y, Zhang Y, Gai Y, Zhang Y, Yu B, Wu J, Wang S, Yu X
The Journal of biological chemistry 2020 Mar 27;295(13):4252-4264
The Journal of biological chemistry 2020 Mar 27;295(13):4252-4264
Design, Synthesis, and Biological Evaluation of Imidazo[1,2-a]pyridine Derivatives as Novel PI3K/mTOR Dual Inhibitors.
Yu Y, Han Y, Zhang F, Gao Z, Zhu T, Dong S, Ma M
Journal of medicinal chemistry 2020 Mar 26;63(6):3028-3046
Journal of medicinal chemistry 2020 Mar 26;63(6):3028-3046
Changed PGA and POSTN levels in choroid plexus are associated with depressive-like behaviors in mice.
Liu J, He Y, Cheng K, Xie P
Biochemical and biophysical research communications 2020 Mar 26;524(1):231-235
Biochemical and biophysical research communications 2020 Mar 26;524(1):231-235
KLF5 Is Crucial for Androgen-AR Signaling to Transactivate Genes and Promote Cell Proliferation in Prostate Cancer Cells.
Li J, Zhang B, Liu M, Fu X, Ci X, A J, Fu C, Dong G, Wu R, Zhang Z, Fu L, Dong JT
Cancers 2020 Mar 21;12(3)
Cancers 2020 Mar 21;12(3)
Dual regulation of p53 by the ribosome maturation factor SBDS.
Hao Q, Wang J, Chen Y, Wang S, Cao M, Lu H, Zhou X
Cell death & disease 2020 Mar 20;11(3):197
Cell death & disease 2020 Mar 20;11(3):197
Cervical carcinoma risk associate with genetic polymorphisms of NEIL2 gene in Chinese population and its significance as predictive biomarker.
Ye F, Liu J, Wang H, Chen X, Cheng Q, Chen H
Scientific reports 2020 Mar 20;10(1):5136
Scientific reports 2020 Mar 20;10(1):5136
Inhibiting both proline biosynthesis and lipogenesis synergistically suppresses tumor growth.
Liu M, Wang Y, Yang C, Ruan Y, Bai C, Chu Q, Cui Y, Chen C, Ying G, Li B
The Journal of experimental medicine 2020 Mar 2;217(3)
The Journal of experimental medicine 2020 Mar 2;217(3)
Complement Signals Determine Opposite Effects of B Cells in Chemotherapy-Induced Immunity.
Lu Y, Zhao Q, Liao JY, Song E, Xia Q, Pan J, Li Y, Li J, Zhou B, Ye Y, Di C, Yu S, Zeng Y, Su S
Cell 2020 Mar 19;180(6):1081-1097.e24
Cell 2020 Mar 19;180(6):1081-1097.e24
AQP1 modulates tendon stem/progenitor cells senescence during tendon aging.
Chen M, Li Y, Xiao L, Dai G, Lu P, Wang Y, Rui Y
Cell death & disease 2020 Mar 18;11(3):193
Cell death & disease 2020 Mar 18;11(3):193
ADORA1 Inhibition Promotes Tumor Immune Evasion by Regulating the ATF3-PD-L1 Axis.
Liu H, Kuang X, Zhang Y, Ye Y, Li J, Liang L, Xie Z, Weng L, Guo J, Li H, Ma F, Chen X, Zhao S, Su J, Yang N, Fang F, Xie Y, Tao J, Zhang J, Chen M, Peng C, Sun L, Zhang X, Liu J, Han L, Xu X, Hung MC, Chen X
Cancer cell 2020 Mar 16;37(3):324-339.e8
Cancer cell 2020 Mar 16;37(3):324-339.e8
PHLDA1 is a new therapeutic target of oxidative stress and ischemia reperfusion-induced myocardial injury.
Guo Y, Jia P, Chen Y, Yu H, Xin X, Bao Y, Yang H, Wu N, Sun Y, Jia D
Life sciences 2020 Mar 15;245:117347
Life sciences 2020 Mar 15;245:117347
Design, synthesis, biological evaluation of 6-(2-amino-1H-benzo[d]imidazole-6-yl)quinazolin-4(3H)-one derivatives as novel anticancer agents with Aurora kinase inhibition.
Fan C, Zhong T, Yang H, Yang Y, Wang D, Yang X, Xu Y, Fan Y
European journal of medicinal chemistry 2020 Mar 15;190:112108
European journal of medicinal chemistry 2020 Mar 15;190:112108
Mesencephalic astrocyte-derived neurotrophic factor ameliorates steatosis in HepG2 cells by regulating hepatic lipid metabolism.
He M, Wang C, Long XH, Peng JJ, Liu DF, Yang GY, Jensen MD, Zhang LL
World journal of gastroenterology 2020 Mar 14;26(10):1029-1041
World journal of gastroenterology 2020 Mar 14;26(10):1029-1041
Pellino1 regulates neuropathic pain as well as microglial activation through the regulation of MAPK/NF-κB signaling in the spinal cord.
Wang L, Yin C, Liu T, Abdul M, Zhou Y, Cao JL, Lu C
Journal of neuroinflammation 2020 Mar 14;17(1):83
Journal of neuroinflammation 2020 Mar 14;17(1):83
Western diet induces severe nonalcoholic steatohepatitis, ductular reaction, and hepatic fibrosis in liver CGI-58 knockout mice.
Yang P, Wang Y, Tang W, Sun W, Ma Y, Lin S, Jing J, Jiang L, Shi H, Song Z, Yu L
Scientific reports 2020 Mar 13;10(1):4701
Scientific reports 2020 Mar 13;10(1):4701
Dietary Compound Isoliquiritigenin, an Antioxidant from Licorice, Suppresses Triple-Negative Breast Tumor Growth via Apoptotic Death Program Activation in Cell and Xenograft Animal Models.
Lin PH, Chiang YF, Shieh TM, Chen HY, Shih CK, Wang TH, Wang KL, Huang TC, Hong YH, Li SC, Hsia SM
Antioxidants (Basel, Switzerland) 2020 Mar 10;9(3)
Antioxidants (Basel, Switzerland) 2020 Mar 10;9(3)
Controlled release of adenosine from core-shell nanofibers to promote bone regeneration through STAT3 signaling pathway.
Cheng X, Cheng G, Xing X, Yin C, Cheng Y, Zhou X, Jiang S, Tao F, Deng H, Li Z
Journal of controlled release : official journal of the Controlled Release Society 2020 Mar 10;319:234-245
Journal of controlled release : official journal of the Controlled Release Society 2020 Mar 10;319:234-245
LncRNA HCP5 promotes cell proliferation and inhibits apoptosis via miR-27a-3p/IGF-1 axis in human granulosa-like tumor cell line KGN.
Chen Y, Zhang X, An Y, Liu B, Lu M
Molecular and cellular endocrinology 2020 Mar 1;503:110697
Molecular and cellular endocrinology 2020 Mar 1;503:110697
AEBP1 Promotes the Occurrence and Development of Abdominal Aortic Aneurysm by Modulating Inflammation via the NF-κB Pathway.
Ren J, Han Y, Ren T, Fang H, Xu X, Lun Y, Jiang H, Xin S, Zhang J
Journal of atherosclerosis and thrombosis 2020 Mar 1;27(3):255-270
Journal of atherosclerosis and thrombosis 2020 Mar 1;27(3):255-270
Microcystins-LR induced apoptosis via S-nitrosylation of GAPDH in colorectal cancer cells.
Li K, Huang M, Xu P, Wang M, Ye S, Wang Q, Zeng S, Chen X, Gao W, Chen J, Zhang Q, Zhong Z, Sun Y, Liu Q
Ecotoxicology and environmental safety 2020 Mar 1;190:110096
Ecotoxicology and environmental safety 2020 Mar 1;190:110096
miR-144 Mediates High Fat-Induced Changes of Cholesterol Metabolism via Direct Regulation of C/EBPα in the Liver and Isolated Hepatocytes of Yellow Catfish.
Chen G, Wu K, Zhao T, Ling S, Liu W, Luo Z
The Journal of nutrition 2020 Mar 1;150(3):464-474
The Journal of nutrition 2020 Mar 1;150(3):464-474
Suppression of high-mobility group box 1 ameliorates xerostomia in a Sjögren syndrome-triggered mouse model.
Wang D, Zhou M, Wang Y, Sun S
Canadian journal of physiology and pharmacology 2020 Jun;98(6):351-356
Canadian journal of physiology and pharmacology 2020 Jun;98(6):351-356
Nbr1-regulated autophagy in Lactoferrin-induced osteoblastic differentiation.
Zhang Y, Zhang ZN, Li N, Zhao LJ, Xue Y, Wu HJ, Hou JM
Bioscience, biotechnology, and biochemistry 2020 Jun;84(6):1191-1200
Bioscience, biotechnology, and biochemistry 2020 Jun;84(6):1191-1200
Antibody microarray analysis of serum inflammatory cytokines in patients with calcific aortic valve disease.
Fu B, Zhang Y, Chen Q, Guo Z, Jiang N
Annals of translational medicine 2020 Jun;8(12):761
Annals of translational medicine 2020 Jun;8(12):761
Fam83d modulates MAP kinase and AKT signaling and is induced during neurogenic skeletal muscle atrophy.
Cooper LM, Hanson A, Kavanagh JA, Waddell DS
Cellular signalling 2020 Jun;70:109576
Cellular signalling 2020 Jun;70:109576
Expression, location and biological effects of four and a half LIM domain protein 2 (FHL2) on granulosa cells in ovine.
Zhang L, Li R, Chen L, Xing Z, Song Y, Nie X, Wang L, Han H, Liu A, Ma X, Ma RZ, Tian S
Reproduction in domestic animals = Zuchthygiene 2020 Jun;55(6):737-746
Reproduction in domestic animals = Zuchthygiene 2020 Jun;55(6):737-746
TNF-α/HMGB1 inflammation signalling pathway regulates pyroptosis during liver failure and acute kidney injury.
Wang Y, Zhang H, Chen Q, Jiao F, Shi C, Pei M, Lv J, Zhang H, Wang L, Gong Z
Cell proliferation 2020 Jun;53(6):e12829
Cell proliferation 2020 Jun;53(6):e12829
TGM3 promotes epithelial-mesenchymal transition and hepatocellular carcinogenesis and predicts poor prognosis for patients after curative resection.
Hu JW, Yang ZF, Li J, Hu B, Luo CB, Zhu K, Dai Z, Cai JB, Zhan H, Hu ZQ, Hu J, Cao Y, Qiu SJ, Zhou J, Fan J, Huang XW
Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 2020 Jun;52(6):668-676
Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 2020 Jun;52(6):668-676
Enhanced tenogenic differentiation and tendon-like tissue formation by Scleraxis overexpression in human amniotic mesenchymal stem cells.
Zhu X, Liu Z, Wu S, Li Y, Xiong H, Zou G, Jin Y, Yang J, You Q, Zhang J, Liu Y
Journal of molecular histology 2020 Jun;51(3):209-220
Journal of molecular histology 2020 Jun;51(3):209-220
Effects of hyperoxia exposure on the expression of Nrf2 and heme oxygenase-1 in lung tissues of premature rats.
Chu X, Zhang X, Gong X, Zhou H, Cai C
Molecular and cellular probes 2020 Jun;51:101529
Molecular and cellular probes 2020 Jun;51:101529
EMT related circular RNA expression profiles identify circSCYL2 as a novel molecule in breast tumor metastasis.
Yuan C, Luo X, Zhan X, Zeng H, Duan S
International journal of molecular medicine 2020 Jun;45(6):1697-1710
International journal of molecular medicine 2020 Jun;45(6):1697-1710
Alda-1, an Aldehyde Dehydrogenase 2 Agonist, Improves Cutaneous Wound Healing by Activating Epidermal Keratinocytes via Akt/GSK-3β/β-Catenin Pathway.
Zhang S, Chen C, Ying J, Wei C, Wang L, Yang Z, Qi F
Aesthetic plastic surgery 2020 Jun;44(3):993-1005
Aesthetic plastic surgery 2020 Jun;44(3):993-1005
Leucine-rich repeat containing 4 act as an autophagy inhibitor that restores sensitivity of glioblastoma to temozolomide.
Feng J, Zhang Y, Ren X, Li D, Fu H, Liu C, Zhou W, Liu Q, Liu Q, Wu M
Oncogene 2020 Jun;39(23):4551-4566
Oncogene 2020 Jun;39(23):4551-4566
Altered expression of AKT1 and P38A in the colons of patients with Hirschsprung's disease.
Wu L, Xiao P, Li Q, Zhang Z, Wang H, Jiang Q, Li L
Pediatric surgery international 2020 Jun;36(6):719-725
Pediatric surgery international 2020 Jun;36(6):719-725
Ghrelin promotes neural differentiation of adipose tissue-derived mesenchymal stem cell via AKT/mTOR and β-catenin signaling pathways.
Liu GB, Pan YM, Liu YS, Hu JH, Zhang XD, Zhang DW, Wang Y, Feng YK, Yu JB, Cheng YX
The Kaohsiung journal of medical sciences 2020 Jun;36(6):405-416
The Kaohsiung journal of medical sciences 2020 Jun;36(6):405-416
Berardinelli-Seip congenital lipodystrophy 2/SEIPIN determines brown adipose tissue maintenance and thermogenic programing.
Zhou H, Xu C, Lee H, Yoon Y, Chen W
Molecular metabolism 2020 Jun;36:100971
Molecular metabolism 2020 Jun;36:100971
Neuroprotective effects of miR-532-5p against ischemic stroke.
Mu J, Cheng X, Zhong S, Chen X, Zhao C
Metabolic brain disease 2020 Jun;35(5):753-763
Metabolic brain disease 2020 Jun;35(5):753-763
Upregulation of miR-219a-5p Decreases Cerebral Ischemia/Reperfusion Injury In Vitro by Targeting Pde4d.
Lu MY, Wu JR, Liang RB, Wang YP, Zhu YC, Ma ZT, Zhang H, Zan J, Tan W
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association 2020 Jun;29(6):104801
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association 2020 Jun;29(6):104801
Integrin β3, a RACK1 interacting protein, is critical for porcine reproductive and respiratory syndrome virus infection and NF-κB activation in Marc-145 cells.
Yang C, Lan R, Wang X, Zhao Q, Li X, Bi J, Wang J, Yang G, Lin Y, Liu J, Yin G
Virus research 2020 Jun;282:197956
Virus research 2020 Jun;282:197956
The E3 ubiquitin ligase TRIM7 suppressed hepatocellular carcinoma progression by directly targeting Src protein.
Zhu L, Qin C, Li T, Ma X, Qiu Y, Lin Y, Ma D, Qin Z, Sun C, Shen X, Zhao Y, Han L
Cell death and differentiation 2020 Jun;27(6):1819-1831
Cell death and differentiation 2020 Jun;27(6):1819-1831
Inflammatory injury and mitophagy induced by Cr(VI) in chicken liver.
Wang Y, Hao J, Zhang S, Li L, Wang R, Zhu Y, Liu Y, Liu J
Environmental science and pollution research international 2020 Jun;27(18):22980-22988
Environmental science and pollution research international 2020 Jun;27(18):22980-22988
Knockdown of p66ShcA activates Nrf2 pathway to protect cardiomyocytes from oxidative stress and inflammation induced by H2O2.
Liu B, Jia N, Wei HL, Lan M, Liu JM, Xue YZ
European review for medical and pharmacological sciences 2020 Jun;24(12):6994-7001
European review for medical and pharmacological sciences 2020 Jun;24(12):6994-7001
MiR-126 regulated myocardial autophagy on myocardial infarction.
Shi CC, Pan LY, Peng ZY, Li JG
European review for medical and pharmacological sciences 2020 Jun;24(12):6971-6979
European review for medical and pharmacological sciences 2020 Jun;24(12):6971-6979
Seizure-induced impairment in neuronal ketogenesis: Role of zinc-α2-glycoprotein in mitochondria.
Tan C, Liu X, Peng W, Wang H, Zhou W, Jiang J, Wei X, Mo L, Chen Y, Chen L
Journal of cellular and molecular medicine 2020 Jun;24(12):6833-6845
Journal of cellular and molecular medicine 2020 Jun;24(12):6833-6845
Endogenous thrombopoietin promotes non-small-cell lung carcinoma cell proliferation and migration by regulating EGFR signalling.
Zou Z, Fan X, Liu Y, Sun Y, Zhang X, Sun G, Li X, Xu S
Journal of cellular and molecular medicine 2020 Jun;24(12):6644-6657
Journal of cellular and molecular medicine 2020 Jun;24(12):6644-6657
A study of the effects of SGLT-2 inhibitors on diabetic cardiomyopathy through miR-30d/KLF9/VEGFA pathway.
Zhang WY, Wang J, Li AZ
European review for medical and pharmacological sciences 2020 Jun;24(11):6346-6359
European review for medical and pharmacological sciences 2020 Jun;24(11):6346-6359
Analysis of deep sequencing exosome-microRNA expression profile derived from CP-II reveals potential role of gga-miRNA-451 in inflammation.
Zhao Y, Fu Y, Zou M, Sun Y, Yin X, Niu L, Gong Y, Peng X
Journal of cellular and molecular medicine 2020 Jun;24(11):6178-6190
Journal of cellular and molecular medicine 2020 Jun;24(11):6178-6190
An upstream open reading frame regulates vasculogenic mimicry of glioma via ZNRD1-AS1/miR-499a-5p/ELF1/EMI1 pathway.
Wang M, Yang C, Liu X, Zheng J, Xue Y, Ruan X, Shen S, Wang D, Li Z, Cai H, Liu Y
Journal of cellular and molecular medicine 2020 Jun;24(11):6120-6136
Journal of cellular and molecular medicine 2020 Jun;24(11):6120-6136
Rice Protein Exerts Endogenous Antioxidant Capacity via Methionine Sulfoxide Reductase and the Nrf2 Antioxidant System Independent of Age.
Li H, Liang M, Wang Z, Zhang Y, Wu Q, Yang L
Journal of medicinal food 2020 Jun;23(6):565-574
Journal of medicinal food 2020 Jun;23(6):565-574
BMP4 resets mouse epiblast stem cells to naive pluripotency through ZBTB7A/B-mediated chromatin remodelling.
Yu S, Zhou C, Cao S, He J, Cai B, Wu K, Qin Y, Huang X, Xiao L, Ye J, Xu S, Xie W, Kuang J, Chu S, Guo J, Liu H, Pang W, Guo L, Zeng M, Wang X, Luo R, Li C, Zhao G, Wang B, Wu L, Chen J, Liu J, Pei D
Nature cell biology 2020 Jun;22(6):651-662
Nature cell biology 2020 Jun;22(6):651-662
MicroRNA‑28 promotes the proliferation of non‑small‑cell lung cancer cells by targeting PTEN.
Cui F, Zhou Q, Xiao K, Qian H
Molecular medicine reports 2020 Jun;21(6):2589-2596
Molecular medicine reports 2020 Jun;21(6):2589-2596
Bisphenol a affects endometrial stromal cells decidualization, involvement of epigenetic regulation.
Xiong Y, Wen X, Liu H, Zhang M, Zhang Y
The Journal of steroid biochemistry and molecular biology 2020 Jun;200:105640
The Journal of steroid biochemistry and molecular biology 2020 Jun;200:105640
Biointerface anisotropy modulates migration of breast cancer cell.
Dai J, Wang Y, Gong J, Yao Y
Colloids and surfaces. B, Biointerfaces 2020 Jun;190:110973
Colloids and surfaces. B, Biointerfaces 2020 Jun;190:110973
PTPN3 Inhibits the Growth and Metastasis of Clear Cell Renal Cell Carcinoma via Inhibition of PI3K/AKT Signaling.
Peng XS, Yang JP, Qiang YY, Sun R, Cao Y, Zheng LS, Peng LX, Lang YH, Mei Y, Li CZ, Meng DF, Liu ZJ, Wang MD, Zhou FJ, Huang BJ, Qian CN
Molecular cancer research : MCR 2020 Jun;18(6):903-912
Molecular cancer research : MCR 2020 Jun;18(6):903-912
Meprin-α (Mep1A) enhances TNF-α secretion by mast cells and aggravates abdominal aortic aneurysms.
Gao R, Liu D, Guo W, Ge W, Fan T, Li B, Gao P, Liu B, Zheng Y, Wang J
British journal of pharmacology 2020 Jun;177(12):2872-2885
British journal of pharmacology 2020 Jun;177(12):2872-2885
DHA attenuates Aβ-induced necroptosis through the RIPK1/RIPK3 signaling pathway in THP-1 monocytes.
Yuan S, Li H, Yang C, Xie W, Wang Y, Zhang J, Cai Z, Mao Z, Xie W, Lü T
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Jun;126:110102
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Jun;126:110102
Modified citrus pectin ameliorates myocardial fibrosis and inflammation via suppressing galectin-3 and TLR4/MyD88/NF-κB signaling pathway.
Xu GR, Zhang C, Yang HX, Sun JH, Zhang Y, Yao TT, Li Y, Ruan L, An R, Li AY
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Jun;126:110071
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Jun;126:110071
Interference with SMO increases chemotherapy drug sensitivity of A2780/DDP cells by inhibiting the Hh/Gli signaling pathway.
Ma S, Liu D, Tan W, Du B, Liu W, Li W, Jiao Y
Journal of cellular biochemistry 2020 Jun;121(5-6):3256-3265
Journal of cellular biochemistry 2020 Jun;121(5-6):3256-3265
Long noncoding RNA linc00467 plays an oncogenic role in hepatocellular carcinoma by regulating the miR-18a-5p/NEDD9 axis.
Zheng Y, Nie P, Xu S
Journal of cellular biochemistry 2020 Jun;121(5-6):3135-3144
Journal of cellular biochemistry 2020 Jun;121(5-6):3135-3144
Activator of thyroid and retinoid receptor increases sorafenib resistance in hepatocellular carcinoma by facilitating the Warburg effect.
Ma L, Liu W, Xu A, Ji Q, Ma Y, Tai Y, Wang Y, Shen C, Liu Y, Wang T, Han J, Zhao C
Cancer science 2020 Jun;111(6):2028-2040
Cancer science 2020 Jun;111(6):2028-2040
Oxidative stress induces monocyte-to-myofibroblast transdifferentiation through p38 in pancreatic ductal adenocarcinoma.
Huang X, He C, Hua X, Kan A, Mao Y, Sun S, Duan F, Wang J, Huang P, Li S
Clinical and translational medicine 2020 Jun;10(2):e41
Clinical and translational medicine 2020 Jun;10(2):e41
T-cell activation and immune memory enhancement induced by irreversible electroporation in pancreatic cancer.
He C, Huang X, Zhang Y, Lin X, Li S
Clinical and translational medicine 2020 Jun;10(2):e39
Clinical and translational medicine 2020 Jun;10(2):e39
The effect of swimming exercise and diet on the hypothalamic inflammation of ApoE-/- mice based on SIRT1-NF-κB-GnRH expression.
Wang X, Yang J, Lu T, Zhan Z, Wei W, Lyu X, Jiang Y, Xue X
Aging 2020 Jun 9;12(11):11085-11099
Aging 2020 Jun 9;12(11):11085-11099
Highly expressed STAT1 contributes to the suppression of stemness properties in human paclitaxel-resistant ovarian cancer cells.
Wang F, Zhang L, Liu J, Zhang J, Xu G
Aging 2020 Jun 9;12(11):11042-11060
Aging 2020 Jun 9;12(11):11042-11060
Gan Shen Fu Fang ameliorates liver fibrosis in vitro and in vivo by inhibiting the inflammatory response and extracellular signal-regulated kinase phosphorylation.
Du QH, Zhang CJ, Li WH, Mu Y, Xu Y, Lowe S, Han L, Yu X, Wang SY, Li Y, Li J
World journal of gastroenterology 2020 Jun 7;26(21):2810-2820
World journal of gastroenterology 2020 Jun 7;26(21):2810-2820
Progranulin inhibits LPS-induced macrophage M1 polarization via NF-кB and MAPK pathways.
Liu L, Guo H, Song A, Huang J, Zhang Y, Jin S, Li S, Zhang L, Yang C, Yang P
BMC immunology 2020 Jun 5;21(1):32
BMC immunology 2020 Jun 5;21(1):32
Role of ANKHD1/LINC00346/ZNF655 Feedback Loop in Regulating the Glioma Angiogenesis via Staufen1-Mediated mRNA Decay.
Yang C, Zheng J, Liu X, Xue Y, He Q, Dong Y, Wang D, Li Z, Liu L, Ma J, Cai H, Liu Y
Molecular therapy. Nucleic acids 2020 Jun 5;20:866-878
Molecular therapy. Nucleic acids 2020 Jun 5;20:866-878
lncRNA LINC00665 Stabilized by TAF15 Impeded the Malignant Biological Behaviors of Glioma Cells via STAU1-Mediated mRNA Degradation.
Ruan X, Zheng J, Liu X, Liu Y, Liu L, Ma J, He Q, Yang C, Wang D, Cai H, Li Z, Liu J, Xue Y
Molecular therapy. Nucleic acids 2020 Jun 5;20:823-840
Molecular therapy. Nucleic acids 2020 Jun 5;20:823-840
Minocycline alleviates NLRP3 inflammasome-dependent pyroptosis in monosodium glutamate-induced depressive rats.
Yang F, Zhu W, Cai X, Zhang W, Yu Z, Li X, Zhang J, Cai M, Xiang J, Cai D
Biochemical and biophysical research communications 2020 Jun 4;526(3):553-559
Biochemical and biophysical research communications 2020 Jun 4;526(3):553-559
Loss of CHCHD2 and CHCHD10 activates OMA1 peptidase to disrupt mitochondrial cristae phenocopying patient mutations.
Liu YT, Huang X, Nguyen D, Shammas MK, Wu BP, Dombi E, Springer DA, Poulton J, Sekine S, Narendra DP
Human molecular genetics 2020 Jun 3;29(9):1547-1567
Human molecular genetics 2020 Jun 3;29(9):1547-1567
Integrative Analysis of NSCLC Identifies LINC01234 as an Oncogenic lncRNA that Interacts with HNRNPA2B1 and Regulates miR-106b Biogenesis.
Chen Z, Chen X, Lei T, Gu Y, Gu J, Huang J, Lu B, Yuan L, Sun M, Wang Z
Molecular therapy : the journal of the American Society of Gene Therapy 2020 Jun 3;28(6):1479-1493
Molecular therapy : the journal of the American Society of Gene Therapy 2020 Jun 3;28(6):1479-1493
SRSF10 inhibits biogenesis of circ-ATXN1 to regulate glioma angiogenesis via miR-526b-3p/MMP2 pathway.
Liu X, Shen S, Zhu L, Su R, Zheng J, Ruan X, Shao L, Wang D, Yang C, Liu Y
Journal of experimental & clinical cancer research : CR 2020 Jun 29;39(1):121
Journal of experimental & clinical cancer research : CR 2020 Jun 29;39(1):121
Deletion of the Impg2 gene causes the degeneration of rod and cone cells in mice.
Xu H, Qu C, Gan L, Sun K, Tan J, Liu X, Jiang Z, Tian W, Liu W, Zhang S, Yang Y, Jiang L, Zhu X, Zhang L
Human molecular genetics 2020 Jun 27;29(10):1624-1634
Human molecular genetics 2020 Jun 27;29(10):1624-1634
Pyrroloquinoline Quinone Inhibits Oxidative Stress in Rats with Diabetic Nephropathy.
Zhang M, Zhang J, Xiong Y, Peng J, Wu X
Medical science monitor : international medical journal of experimental and clinical research 2020 Jun 27;26:e924372
Medical science monitor : international medical journal of experimental and clinical research 2020 Jun 27;26:e924372
Cimifugin ameliorates imiquimod-induced psoriasis by inhibiting oxidative stress and inflammation via NF-κB/MAPK pathway.
Liu A, Zhao W, Zhang B, Tu Y, Wang Q, Li J
Bioscience reports 2020 Jun 26;40(6)
Bioscience reports 2020 Jun 26;40(6)
STEAP1 facilitates metastasis and epithelial-mesenchymal transition of lung adenocarcinoma via the JAK2/STAT3 signaling pathway.
Huo SF, Shang WL, Yu M, Ren XP, Wen HX, Chai CY, Sun L, Hui K, Liu LH, Wei SH, Wang XX, Wang Y, Tian YX
Bioscience reports 2020 Jun 26;40(6)
Bioscience reports 2020 Jun 26;40(6)
Chi-miR-30b-5p inhibits dermal papilla cells proliferation by targeting CaMKIIδ gene in cashmere goat.
Zhang Y, Xia S, Wang T, Wang S, Yuan D, Li F, Wang X
BMC genomics 2020 Jun 26;21(1):430
BMC genomics 2020 Jun 26;21(1):430
The PABPC5/HCG15/ZNF331 Feedback Loop Regulates Vasculogenic Mimicry of Glioma via STAU1-Mediated mRNA Decay.
Jing F, Ruan X, Liu X, Yang C, Wang D, Zheng J, Xue Y, Shen S, Shao L, Yang Y, Wang P, Ma J, Liu Y
Molecular therapy oncolytics 2020 Jun 26;17:216-231
Molecular therapy oncolytics 2020 Jun 26;17:216-231
Overexpression of YBX1 Promotes Pancreatic Ductal Adenocarcinoma Growth via the GSK3B/Cyclin D1/Cyclin E1 Pathway.
Liu Z, Li Y, Li X, Zhao J, Wu S, Wu H, Gou S
Molecular therapy oncolytics 2020 Jun 26;17:21-30
Molecular therapy oncolytics 2020 Jun 26;17:21-30
RBFOX1 Regulates the Permeability of the Blood-Tumor Barrier via the LINC00673/MAFF Pathway.
Shen S, Yang C, Liu X, Zheng J, Liu Y, Liu L, Ma J, Ma T, An P, Lin Y, Cai H, Wang D, Li Z, Zhao L, Xue Y
Molecular therapy oncolytics 2020 Jun 26;17:138-152
Molecular therapy oncolytics 2020 Jun 26;17:138-152
MicroRNA-675-3p regulates IL-1β-stimulated human chondrocyte apoptosis and cartilage degradation by targeting GNG5.
Shen XF, Cheng Y, Dong QR, Zheng MQ
Biochemical and biophysical research communications 2020 Jun 25;527(2):458-465
Biochemical and biophysical research communications 2020 Jun 25;527(2):458-465
Circular RNA circ_0111277 attenuates human trophoblast cell invasion and migration by regulating miR-494/HTRA1/Notch-1 signal pathway in pre-eclampsia.
Ou Y, Zhu L, Wei X, Bai S, Chen M, Chen H, Zhang J
Cell death & disease 2020 Jun 25;11(6):479
Cell death & disease 2020 Jun 25;11(6):479
Targeted Delivery of Notch Inhibitor Attenuates Obesity-Induced Glucose Intolerance and Liver Fibrosis.
Richter LR, Wan Q, Wen D, Zhang Y, Yu J, Kang JK, Zhu C, McKinnon EL, Gu Z, Qiang L, Pajvani UB
ACS nano 2020 Jun 23;14(6):6878-6886
ACS nano 2020 Jun 23;14(6):6878-6886
α7nAchR mediates transcutaneous auricular vagus nerve stimulation-induced neuroprotection in a rat model of ischemic stroke by enhancing axonal plasticity.
Li J, Zhang Q, Li S, Niu L, Ma J, Wen L, Zhang L, Li C
Neuroscience letters 2020 Jun 21;730:135031
Neuroscience letters 2020 Jun 21;730:135031
Analysis of RAS protein interactions in living cells reveals a mechanism for pan-RAS depletion by membrane-targeted RAS binders.
Li YC, Lytle NK, Gammon ST, Wang L, Hayes TK, Sutton MN, Bast RC Jr, Der CJ, Piwnica-Worms D, McCormick F, Wahl GM
Proceedings of the National Academy of Sciences of the United States of America 2020 Jun 2;117(22):12121-12130
Proceedings of the National Academy of Sciences of the United States of America 2020 Jun 2;117(22):12121-12130
Immune activation of murine RAW264.7 macrophages by sonicated and alkalized paramylon from Euglena gracilis.
Guo Q, Bi D, Wu M, Yu B, Hu L, Liu C, Gu L, Zhu H, Lei A, Xu X, Wang J
BMC microbiology 2020 Jun 19;20(1):171
BMC microbiology 2020 Jun 19;20(1):171
LUZP1, a novel regulator of primary cilia and the actin cytoskeleton, is a contributing factor in Townes-Brocks Syndrome.
Bozal-Basterra L, Gonzalez-Santamarta M, Muratore V, Bermejo-Arteagabeitia A, Da Fonseca C, Barroso-Gomila O, Azkargorta M, Iloro I, Pampliega O, Andrade R, Martín-Martín N, Branon TC, Ting AY, Rodríguez JA, Carracedo A, Elortza F, Sutherland JD, Barrio R
eLife 2020 Jun 18;9
eLife 2020 Jun 18;9
Long noncoding RNA LINC00314 facilitates osteogenic differentiation of adipose-derived stem cells through the hsa-miR-129-5p/GRM5 axis via the Wnt signaling pathway.
Shi ZL, Zhang H, Fan ZY, Ma W, Song YZ, Li M, Li TQ, Cao SX, Feng GJ
Stem cell research & therapy 2020 Jun 17;11(1):240
Stem cell research & therapy 2020 Jun 17;11(1):240
Pannexin1 Channel Inhibitor ((10)panx) Protects Against Transient Focal Cerebral Ischemic Injury by Inhibiting RIP3 Expression and Inflammatory Response in Rats.
Wei R, Bao W, He F, Meng F, Liang H, Luo B
Neuroscience 2020 Jun 15;437:23-33
Neuroscience 2020 Jun 15;437:23-33
IL-4 Switches Microglia/macrophage M1/M2 Polarization and Alleviates Neurological Damage by Modulating the JAK1/STAT6 Pathway Following ICH.
He Y, Gao Y, Zhang Q, Zhou G, Cao F, Yao S
Neuroscience 2020 Jun 15;437:161-171
Neuroscience 2020 Jun 15;437:161-171
Perinatal low-dose PBDE-47 exposure hampered thyroglobulin turnover and induced thyroid cell apoptosis by triggering ER stress and lysosomal destabilization contributing to thyroid toxicity in adult female rats.
Li P, Gao H, Dong L, Liu L, Zhou G, Luo C, Tian Z, Xia T, Wang A, Zhang S
Journal of hazardous materials 2020 Jun 15;392:122265
Journal of hazardous materials 2020 Jun 15;392:122265
β-catenin-mediated Wnt signal transduction proceeds through an endocytosis-independent mechanism.
Rim EY, Kinney LK, Nusse R
Molecular biology of the cell 2020 Jun 15;31(13):1425-1436
Molecular biology of the cell 2020 Jun 15;31(13):1425-1436
Major depression accompanied with inflammation and multiple cytokines alterations: Evidences from clinical patients to macaca fascicularis and LPS-induced depressive mice model.
He Y, Li W, Wang Y, Tian Y, Chen X, Wu Z, Lan T, Li Y, Bai M, Liu J, Cheng K, Xie P
Journal of affective disorders 2020 Jun 15;271:262-271
Journal of affective disorders 2020 Jun 15;271:262-271
PLK1 Inhibition alleviates transplant-associated obliterative bronchiolitis by suppressing myofibroblast differentiation.
Yu J, Xu H, Cui J, Chen S, Zhang H, Zou Y, Zhao J, Le S, Jiang L, Chen Z, Liu H, Zhang D, Xia J, Wu J
Aging 2020 Jun 15;12(12):11636-11652
Aging 2020 Jun 15;12(12):11636-11652
Non-Esterified Fatty Acid-Induced Reactive Oxygen Species Mediated Granulosa Cells Apoptosis Is Regulated by Nrf2/p53 Signaling Pathway.
Wang Y, Li C, Li J, Wang G, Li L
Antioxidants (Basel, Switzerland) 2020 Jun 14;9(6)
Antioxidants (Basel, Switzerland) 2020 Jun 14;9(6)
Qian Yang Yu Yin Granule protects against hypertension-induced renal injury by epigenetic mechanism linked to Nicotinamide N-Methyltransferase (NNMT) expression.
Zhang SF, Mao XJ, Jiang WM, Fang ZY
Journal of ethnopharmacology 2020 Jun 12;255:112738
Journal of ethnopharmacology 2020 Jun 12;255:112738
Ginsenoside Rg3 promotes regression from hepatic fibrosis through reducing inflammation-mediated autophagy signaling pathway.
Liu X, Mi X, Wang Z, Zhang M, Hou J, Jiang S, Wang Y, Chen C, Li W
Cell death & disease 2020 Jun 12;11(6):454
Cell death & disease 2020 Jun 12;11(6):454
Circular RNA circZNF566 promotes hepatocellular carcinoma progression by sponging miR-4738-3p and regulating TDO2 expression.
Li S, Weng J, Song F, Li L, Xiao C, Yang W, Xu J
Cell death & disease 2020 Jun 12;11(6):452
Cell death & disease 2020 Jun 12;11(6):452
TSPO ligand Ro5-4864 modulates microglia/macrophages polarization after subarachnoid hemorrhage in mice.
Zhou J, Zhang X, Peng J, Xie Y, Du F, Guo K, Feng Y, Zhang L, Chen L, Jiang Y
Neuroscience letters 2020 Jun 11;729:134977
Neuroscience letters 2020 Jun 11;729:134977
Knockdown of fibronectin extra domain B suppresses TGF-β1-mediated cell proliferation and collagen deposition in keloid fibroblasts via AKT/ERK signaling pathway.
Cui J, Li Z, Jin C, Jin Z
Biochemical and biophysical research communications 2020 Jun 11;526(4):1131-1137
Biochemical and biophysical research communications 2020 Jun 11;526(4):1131-1137
Circular RNA (circRNA) CDYL Induces Myocardial Regeneration by ceRNA After Myocardial Infarction.
Zhang M, Wang Z, Cheng Q, Wang Z, Lv X, Wang Z, Li N
Medical science monitor : international medical journal of experimental and clinical research 2020 Jun 11;26:e923188
Medical science monitor : international medical journal of experimental and clinical research 2020 Jun 11;26:e923188
M6A-related bioinformatics analysis reveals that HNRNPC facilitates progression of OSCC via EMT.
Huang GZ, Wu QQ, Zheng ZN, Shao TR, Chen YC, Zeng WS, Lv XZ
Aging 2020 Jun 11;12(12):11667-11684
Aging 2020 Jun 11;12(12):11667-11684
Extrasynaptic CaMKIIα is involved in the antidepressant effects of ketamine by downregulating GluN2B receptors in an LPS-induced depression model.
Tang XH, Zhang GF, Xu N, Duan GF, Jia M, Liu R, Zhou ZQ, Yang JJ
Journal of neuroinflammation 2020 Jun 10;17(1):181
Journal of neuroinflammation 2020 Jun 10;17(1):181
SHQ1 is an ER stress response gene that facilitates chemotherapeutics-induced apoptosis via sensitizing ER-stress response.
Liu H, Xie S, Fang F, Kalvakolanu DV, Xiao W
Cell death & disease 2020 Jun 10;11(6):445
Cell death & disease 2020 Jun 10;11(6):445
Downregulation of BACH1 Protects AGAINST Cerebral Ischemia/Reperfusion Injury through the Functions of HO-1 and NQO1.
Yu S, Zhai J, Yu J, Yang Q, Yang J
Neuroscience 2020 Jun 1;436:154-166
Neuroscience 2020 Jun 1;436:154-166
Phenylephrine alleviates (131)I damage in submandibular gland through promoting endogenous stem cell regeneration via lissencephaly-1 upregulation.
Wang XY, Yu J, Zhang Y, Zhang FY, Liu KJ, Xiang B
Toxicology and applied pharmacology 2020 Jun 1;396:114999
Toxicology and applied pharmacology 2020 Jun 1;396:114999
DNMT1-mediated Foxp3 gene promoter hypermethylation involved in immune dysfunction caused by arsenic in human lymphocytes.
Ma Y, Ye Y, Liu Y, Chen J, Cen Y, Chen W, Yu C, Zeng Q, Zhang A, Yang G
Toxicology research 2020 Jul;9(4):519-529
Toxicology research 2020 Jul;9(4):519-529
ARHGEF10L expression regulates cell proliferation and migration in gastric tumorigenesis.
Wang DW, Tang JY, Zhang GQ, Chang XT
Bioscience, biotechnology, and biochemistry 2020 Jul;84(7):1362-1372
Bioscience, biotechnology, and biochemistry 2020 Jul;84(7):1362-1372
Costunolide improved dextran sulfate sodium-induced acute ulcerative colitis in mice through NF-κB, STAT1/3, and Akt signaling pathways.
Xie F, Zhang H, Zheng C, Shen XF
International immunopharmacology 2020 Jul;84:106567
International immunopharmacology 2020 Jul;84:106567
Acarbose, as a potential drug, effectively blocked the dynamic metastasis of EV71 from the intestine to the whole body.
Feng Q, Zhou H, Zhang X, Liu X, Wang J, Zhang C, Ma X, Quan C, Zheng Z
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases 2020 Jul;81:104210
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases 2020 Jul;81:104210
A mitophagic response to iron overload-induced oxidative damage associated with the PINK1/Parkin pathway in pancreatic beta cells.
Zhang L, Hou L, Liu Z, Huang S, Meng Z, Liang L
Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS) 2020 Jul;60:126493
Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS) 2020 Jul;60:126493
Generation of B6-Ddx4(em1(CreERT2)Utr) , a novel CreERT2 knock-in line, for germ cell lineage by CRISPR/Cas9.
Le HT, Hasegawa Y, Daitoku Y, Kato K, Miznuo-Iijima S, Dinh TTH, Kuba Y, Osawa Y, Mikami N, Morimoto K, Ayabe S, Tanimoto Y, Murata K, Yagami KI, Takahashi S, Mizuno S, Sugiyama F
Genesis (New York, N.Y. : 2000) 2020 Jul;58(7):e23367
Genesis (New York, N.Y. : 2000) 2020 Jul;58(7):e23367
Crocin Reverses Depression-Like Behavior in Parkinson Disease Mice via VTA-mPFC Pathway.
Tang J, Lu L, Wang Q, Liu H, Xue W, Zhou T, Xu L, Wang K, Wu D, Wei F, Tao W, Chen G
Molecular neurobiology 2020 Jul;57(7):3158-3170
Molecular neurobiology 2020 Jul;57(7):3158-3170
HSulf‑1 and palbociclib exert synergistic antitumor effects on RB‑positive triple‑negative breast cancer.
Chen F, Zhang Z, Yu Y, Liu Q, Pu F
International journal of oncology 2020 Jul;57(1):223-236
International journal of oncology 2020 Jul;57(1):223-236
Circulating Exosomes From Lipopolysaccharide-Induced Ards Mice Trigger Endoplasmic Reticulum Stress in Lung Tissue.
Tang X, Yu Q, Wen X, Qi D, Peng J, He J, Deng W, Zhu T, Zhao Y, Wang D
Shock (Augusta, Ga.) 2020 Jul;54(1):110-118
Shock (Augusta, Ga.) 2020 Jul;54(1):110-118
Matrix Metalloproteinase 11 as a Novel Tumor Promoter and Diagnostic and Prognostic Biomarker for Pancreatic Ductal Adenocarcinoma.
Zhang X, Lu J, Zhou L, You L, Liang Z, Guo J, Zhao Y
Pancreas 2020 Jul;49(6):812-821
Pancreas 2020 Jul;49(6):812-821
Methionine Enkephalin Suppresses Osteocyte Apoptosis Induced by Compressive Force through Regulation of Nuclear Translocation of NFATc1.
Sogi C, Takeshita N, Jiang W, Kim S, Maeda T, Yoshida M, Oyanagi T, Ito A, Kimura S, Seki D, Takano I, Sakai Y, Fujiwara I, Kure S, Takano-Yamamoto T
JBMR plus 2020 Jul;4(7):e10369
JBMR plus 2020 Jul;4(7):e10369
S100A14 suppresses metastasis of nasopharyngeal carcinoma by inhibition of NF-kB signaling through degradation of IRAK1.
Meng DF, Sun R, Liu GY, Peng LX, Zheng LS, Xie P, Lin ST, Mei Y, Qiang YY, Li CZ, Xu L, Peng XS, Hu H, Lang YH, Liu ZJ, Wang MD, Guo LL, Xie DH, Shu DT, Li HF, Luo FF, Niu XT, Huang BJ, Qian CN
Oncogene 2020 Jul;39(30):5307-5322
Oncogene 2020 Jul;39(30):5307-5322
Transcription factorIRX5 promotes hepatocellular carcinoma proliferation and inhibits apoptosis by regulating the p53 signalling pathway.
Zhu L, Dai L, Yang N, Liu M, Ma S, Li C, Shen J, Lin T, Wang D, Pan W, Li X
Cell biochemistry and function 2020 Jul;38(5):621-629
Cell biochemistry and function 2020 Jul;38(5):621-629
Thyrotropin receptor signaling deficiency impairs spatial learning and memory in mice.
Luan S, Bi W, Shi S, Peng L, Li Z, Jiang J, Gao L, Du Y, Hou X, He Z, Zhao J
The Journal of endocrinology 2020 Jul;246(1):41-55
The Journal of endocrinology 2020 Jul;246(1):41-55
Porcine RACK1 negatively regulates the infection of classical swine fever virus and the NF-κB activation in PK-15 cells.
Wang X, Gao L, Yang X, Zuo Q, Lan R, Li M, Yang C, Lin Y, Liu J, Yin G
Veterinary microbiology 2020 Jul;246:108711
Veterinary microbiology 2020 Jul;246:108711
UHRF1 predicts poor prognosis by triggering cell cycle in lung adenocarcinoma.
Tu Z, Deng X, Hou S, Feng A, Zhang Q
Journal of cellular and molecular medicine 2020 Jul;24(14):8069-8077
Journal of cellular and molecular medicine 2020 Jul;24(14):8069-8077
p75NTR optimizes the osteogenic potential of human periodontal ligament stem cells by up-regulating α1 integrin expression.
Li J, Zhao M, Wang Y, Shen M, Wang S, Tang M, Li M, Luo Y, Yang K, Wen X
Journal of cellular and molecular medicine 2020 Jul;24(13):7563-7575
Journal of cellular and molecular medicine 2020 Jul;24(13):7563-7575
Progress in the research of p53 tumour suppressor activity controlled by Numb in triple-negative breast cancer.
Xian J, Cheng Y, Qin X, Cao Y, Luo Y, Cao Y
Journal of cellular and molecular medicine 2020 Jul;24(13):7451-7459
Journal of cellular and molecular medicine 2020 Jul;24(13):7451-7459
Autophagy assuages myocardial infarction through Nrf2 signaling activation-mediated reactive oxygen species clear.
Sun B, Xu Y, Liu ZY, Meng WX, Yang H
European review for medical and pharmacological sciences 2020 Jul;24(13):7381-7390
European review for medical and pharmacological sciences 2020 Jul;24(13):7381-7390
Reversal of prolonged obesity-associated cerebrovascular dysfunction by inhibiting microglial Tak1.
Shen Q, Chen Z, Zhao F, Pan S, Zhang T, Cheng X, Zhang L, Zhang S, Qi J, Li J, Cai D, Zhang G
Nature neuroscience 2020 Jul;23(7):832-841
Nature neuroscience 2020 Jul;23(7):832-841
Wnt10b-overexpressing umbilical cord mesenchymal stem cells promote critical size rat calvarial defect healing by enhanced osteogenesis and VEGF-mediated angiogenesis.
Liu Y, Fang J, Zhang Q, Zhang X, Cao Y, Chen W, Shao Z, Yang S, Wu D, Hung M, Zhang Y, Tong W, Tian H
Journal of orthopaedic translation 2020 Jul;23:29-37
Journal of orthopaedic translation 2020 Jul;23:29-37
Antioxidant-related catalase CTA1 regulates development, aflatoxin biosynthesis, and virulence in pathogenic fungus Aspergillus flavus.
Zhu Z, Yang M, Bai Y, Ge F, Wang S
Environmental microbiology 2020 Jul;22(7):2792-2810
Environmental microbiology 2020 Jul;22(7):2792-2810
High expression of CDCA7 predicts tumor progression and poor prognosis in human colorectal cancer.
Li S, Huang J, Qin M, Zhang J, Liao C
Molecular medicine reports 2020 Jul;22(1):57-66
Molecular medicine reports 2020 Jul;22(1):57-66
MicroRNA‑93 promotes angiogenesis and attenuates remodeling via inactivation of the Hippo/Yap pathway by targeting Lats2 after myocardial infarctionω.
Ma C, Peng P, Zhou Y, Liu T, Wang L, Lu C
Molecular medicine reports 2020 Jul;22(1):483-493
Molecular medicine reports 2020 Jul;22(1):483-493
LncRNA MALAT1 affects the migration and invasion of trophoblast cells by regulating FOS expression in early-onset preeclampsia.
Li Q, Wang T, Huang S, Zuo Q, Jiang Z, Yang N, Sun L
Pregnancy hypertension 2020 Jul;21:50-57
Pregnancy hypertension 2020 Jul;21:50-57
Metastasis-associated gene MAPK15 promotes the migration and invasion of osteosarcoma cells via the c-Jun/MMPs pathway.
Su Z, Yang B, Zeng Z, Zhu S, Wang C, Lei S, Jiang Y, Lin L
Oncology letters 2020 Jul;20(1):99-112
Oncology letters 2020 Jul;20(1):99-112
PRR11 and SKA2 promote the proliferation, migration and invasion of esophageal carcinoma cells.
Chen J, Yang HM, Zhou HC, Peng RR, Niu ZX, Kang CY
Oncology letters 2020 Jul;20(1):639-646
Oncology letters 2020 Jul;20(1):639-646
miR-96-5p regulated TGF-β/SMAD signaling pathway and suppressed endometrial cell viability and migration via targeting TGFBR1.
Chen S, Luo Y, Cui L, Yang Q
Cell cycle (Georgetown, Tex.) 2020 Jul;19(14):1740-1753
Cell cycle (Georgetown, Tex.) 2020 Jul;19(14):1740-1753
GL-V9 reverses adriamycin resistance in hepatocellular carcinoma cells by affecting JNK2-related autophagy.
Yang Y, Liao Y, Gui YP, Zhao L, Guo LB
Chinese journal of natural medicines 2020 Jul;18(7):491-499
Chinese journal of natural medicines 2020 Jul;18(7):491-499
Artemisinin inhibits the replication of flaviviruses by promoting the type I interferon production.
Wang X, Zheng B, Ashraf U, Zhang H, Cao C, Li Q, Chen Z, Imran M, Chen H, Cao S, Ye J
Antiviral research 2020 Jul;179:104810
Antiviral research 2020 Jul;179:104810
Label-Free Quantitative Proteomic Profiling of LAD2 Mast Cell Releasates Reveals the Mechanism of Tween-80-Induced Anaphylactoid Reaction.
Mi YN, Yan PP, Di J, Cao L, Xiao X, Liu DZ, Cao YX
Proteomics. Clinical applications 2020 Jul;14(4):e1900065
Proteomics. Clinical applications 2020 Jul;14(4):e1900065
miR-429-CRKL axis regulates clear cell renal cell carcinoma malignant progression through SOS1/MEK/ERK/MMP2/MMP9 pathway.
Wang J, Wang C, Li Q, Guo C, Sun W, Zhao D, Jiang S, Hao L, Tian Y, Liu S, Sun MZ
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Jul;127:110215
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Jul;127:110215
Isocitrate dehydrogenase 2 contributes to radiation resistance of oesophageal squamous cell carcinoma via regulating mitochondrial function and ROS/pAKT signalling.
Chen X, Zhuo S, Xu W, Chen X, Huang D, Sun X, Cheng Y
British journal of cancer 2020 Jul;123(1):126-136
British journal of cancer 2020 Jul;123(1):126-136
Integration of in vitro data from three dimensionally cultured HepaRG cells and physiologically based pharmacokinetic modeling for assessment of acetaminophen hepatotoxicity.
Zhang C, Zhang Q, Li J, Yu L, Li F, Li W, Li Y, Peng H, Zhao J, Carmichael PL, Wang Y, Peng S, Guo J
Regulatory toxicology and pharmacology : RTP 2020 Jul;114:104661
Regulatory toxicology and pharmacology : RTP 2020 Jul;114:104661
High expression of KITLG is a new hallmark activating the MAPK pathway in type A and AB thymoma.
Yang Z, Liu S, Wang Y, Chen Y, Zhang P, Liu Y, Zhang H, Zhang P, Tao Z, Xiong K
Thoracic cancer 2020 Jul;11(7):1944-1954
Thoracic cancer 2020 Jul;11(7):1944-1954
Changes in Nup62 content affect contact-induced differentiation of cultured myoblasts.
Bishop PJ, Kinoshita Y, Lopes NN, Ward AS, Kohtz DS
Differentiation; research in biological diversity 2020 Jul-Aug;114:27-35
Differentiation; research in biological diversity 2020 Jul-Aug;114:27-35
RDP3, A Novel Antigout Peptide Derived from Water Extract of Rice.
Liu N, Wang Y, Zeng L, Yin S, Hu Y, Li S, Fu Y, Zhang X, Xie C, Shu L, Li Y, Sun H, Yang M, Sun J, Yang X
Journal of agricultural and food chemistry 2020 Jul 8;68(27):7143-7151
Journal of agricultural and food chemistry 2020 Jul 8;68(27):7143-7151
Matrine inhibits the growth of natural killer/T-cell lymphoma cells by modulating CaMKIIγ-c-Myc signaling pathway.
Gu J, Zhang Y, Wang X, Xiang J, Deng S, Wu D, Chen J, Yu L, Zhou Y, Wang Y, Shen J
BMC complementary medicine and therapies 2020 Jul 8;20(1):214
BMC complementary medicine and therapies 2020 Jul 8;20(1):214
Opposing biological functions of the cytoplasm and nucleus DAXX modified by SUMO-2/3 in gastric cancer.
Chen C, Sun X, Xie W, Chen S, Hu Y, Xing D, Xu J, Chen X, Zhao Z, Han Z, Xue X, Shen X, Lin K
Cell death & disease 2020 Jul 8;11(7):514
Cell death & disease 2020 Jul 8;11(7):514
κB-Ras and Ral GTPases regulate acinar to ductal metaplasia during pancreatic adenocarcinoma development and pancreatitis.
Beel S, Kolloch L, Apken LH, Jürgens L, Bolle A, Sudhof N, Ghosh S, Wardelmann E, Meisterernst M, Steinestel K, Oeckinghaus A
Nature communications 2020 Jul 8;11(1):3409
Nature communications 2020 Jul 8;11(1):3409
Cerebral Blood Flow-Guided Manipulation of Arterial Blood Pressure Attenuates Hippocampal Apoptosis After Asphyxia-Induced Cardiac Arrest in Rats.
Wang CH, Chang WT, Huang CH, Tsai MS, Liu SH, Chen WJ
Journal of the American Heart Association 2020 Jul 7;9(13):e016513
Journal of the American Heart Association 2020 Jul 7;9(13):e016513
CXCL5 promotes gastric cancer metastasis by inducing epithelial-mesenchymal transition and activating neutrophils.
Mao Z, Zhang J, Shi Y, Li W, Shi H, Ji R, Mao F, Qian H, Xu W, Zhang X
Oncogenesis 2020 Jul 6;9(7):63
Oncogenesis 2020 Jul 6;9(7):63
TRIM24 facilitates antiviral immunity through mediating K63-linked TRAF3 ubiquitination.
Zhu Q, Yu T, Gan S, Wang Y, Pei Y, Zhao Q, Pei S, Hao S, Yuan J, Xu J, Hou F, Wu X, Peng C, Wu P, Qin J, Xiao Y
The Journal of experimental medicine 2020 Jul 6;217(7)
The Journal of experimental medicine 2020 Jul 6;217(7)
Synthesis of a Hexavalent Betulinic Acid Derivative as a Hemagglutinin-Targeted Influenza Virus Entry Inhibitor.
Chen Y, Wang X, Zhu Y, Si L, Zhang B, Zhang Y, Zhang L, Zhou D, Xiao S
Molecular pharmaceutics 2020 Jul 6;17(7):2546-2554
Molecular pharmaceutics 2020 Jul 6;17(7):2546-2554
Spermidine activates RIP1 deubiquitination to inhibit TNF-α-induced NF-κB/p65 signaling pathway in osteoarthritis.
Chen Z, Lin CX, Song B, Li CC, Qiu JX, Li SX, Lin SP, Luo WQ, Fu Y, Fang GB, Wei-Ping L, Saw PE, Ding Y
Cell death & disease 2020 Jul 6;11(7):503
Cell death & disease 2020 Jul 6;11(7):503
Loss of HMGCS2 Enhances Lipogenesis and Attenuates the Protective Effect of the Ketogenic Diet in Liver Cancer.
Wang YH, Suk FM, Liao YJ
Cancers 2020 Jul 4;12(7)
Cancers 2020 Jul 4;12(7)
Apoptotic neurodegeneration in whitefly promotes the spread of TYLCV.
Wang S, Guo H, Ge F, Sun Y
eLife 2020 Jul 30;9
eLife 2020 Jul 30;9
Assessment of insulin resistance in the skeletal muscle of mice using positron emission tomography/computed tomography imaging.
Miyatake Y, Mishima Y, Tsutsumi R, Otani T, Suemasa N, Masumoto S, Kuroda M, Sakaue H
Biochemical and biophysical research communications 2020 Jul 30;528(3):499-505
Biochemical and biophysical research communications 2020 Jul 30;528(3):499-505
Application of Antibodies to Neuronally Expressed Nogo-A Increases Neuronal Survival and Neurite Outgrowth.
Nagaraj V, Theis T, Johal AS, Seth A, Gore J, Arsha N, Patel M, Hao HB, Kurian N, Schachner M
International journal of molecular sciences 2020 Jul 30;21(15)
International journal of molecular sciences 2020 Jul 30;21(15)
EN2 as an oncogene promotes tumor progression via regulating CCL20 in colorectal cancer.
Li Y, Liu J, Xiao Q, Tian R, Zhou Z, Gan Y, Li Y, Shu G, Yin G
Cell death & disease 2020 Jul 30;11(7):604
Cell death & disease 2020 Jul 30;11(7):604
MCF7 Spheroid Development: New Insight about Spatio/Temporal Arrangements of TNTs, Amyloid Fibrils, Cell Connections, and Cellular Bridges.
Pulze L, Congiu T, Brevini TAL, Grimaldi A, Tettamanti G, D'Antona P, Baranzini N, Acquati F, Ferraro F, de Eguileor M
International journal of molecular sciences 2020 Jul 29;21(15)
International journal of molecular sciences 2020 Jul 29;21(15)
LncRNA PVT1 promotes gemcitabine resistance of pancreatic cancer via activating Wnt/β-catenin and autophagy pathway through modulating the miR-619-5p/Pygo2 and miR-619-5p/ATG14 axes.
Zhou C, Yi C, Yi Y, Qin W, Yan Y, Dong X, Zhang X, Huang Y, Zhang R, Wei J, Ali DW, Michalak M, Chen XZ, Tang J
Molecular cancer 2020 Jul 29;19(1):118
Molecular cancer 2020 Jul 29;19(1):118
Sensitive Signal Amplifying a Diagnostic Biochip Based on a Biomimetic Periodic Nanostructure for Detecting Cancer Exosomes.
Zhang J, Zhu Y, Shi J, Zhang K, Zhang Z, Zhang H
ACS applied materials & interfaces 2020 Jul 29;12(30):33473-33482
ACS applied materials & interfaces 2020 Jul 29;12(30):33473-33482
CircATRNL1 promotes epithelial-mesenchymal transition in endometriosis by upregulating Yes-associated protein 1 in vitro.
Wang D, Luo Y, Wang G, Yang Q
Cell death & disease 2020 Jul 29;11(7):594
Cell death & disease 2020 Jul 29;11(7):594
The Impact of ALS-Associated Genes hnRNPA1, MATR3, VCP and UBQLN2 on the Severity of TDP-43 Aggregation.
Bajc Česnik A, Motaln H, Rogelj B
Cells 2020 Jul 28;9(8)
Cells 2020 Jul 28;9(8)
mTORC1-dependent TFEB nucleus translocation and pro-survival autophagy induced by zeolitic imidazolate framework-8.
Ding H, Song Y, Huang X, Wang L, Luo S, Zhang H, Pan H, Jiang W, Qian J, Yao G, Wen L, Zhang Y
Biomaterials science 2020 Jul 28;8(15):4358-4369
Biomaterials science 2020 Jul 28;8(15):4358-4369
Suppression of PTTG1 inhibits cell angiogenesis, migration and invasion in glioma cells.
Cui L, Ren T, Zhao H, Chen S, Zheng M, Gao X, Feng D, Yang L, Jin X, Zhuo R
Medical oncology (Northwood, London, England) 2020 Jul 28;37(8):73
Medical oncology (Northwood, London, England) 2020 Jul 28;37(8):73
Correlation between the HIF-1α/Notch signaling pathway and Modic changes in nucleus pulposus cells isolated from patients with low back pain.
Xiong Z, Ding J, Zhou J, Yao S, Zheng J, Guo X
BMC musculoskeletal disorders 2020 Jul 28;21(1):500
BMC musculoskeletal disorders 2020 Jul 28;21(1):500
Gold Nanoparticles Induce Tumor Vessel Normalization and Impair Metastasis by Inhibiting Endothelial Smad2/3 Signaling.
Huang N, Liu Y, Fang Y, Zheng S, Wu J, Wang M, Zhong W, Shi M, Xing M, Liao W
ACS nano 2020 Jul 28;14(7):7940-7958
ACS nano 2020 Jul 28;14(7):7940-7958
Structural and Biological Basis of Alphacoronavirus nsp1 Associated with Host Proliferation and Immune Evasion.
Shen Z, Yang Y, Yang S, Zhang G, Xiao S, Fu ZF, Peng G
Viruses 2020 Jul 28;12(8)
Viruses 2020 Jul 28;12(8)
The cross-talk between DDR1 and STAT3 promotes the development of hepatocellular carcinoma.
Lin Y, Jin H, Wu X, Jian Z, Zou X, Huang J, Guan R, Wei X
Aging 2020 Jul 27;12(14):14391-14405
Aging 2020 Jul 27;12(14):14391-14405
Histone deacetylase 4 inhibits NF-κB activation by facilitating IκBα sumoylation.
Yang Q, Tang J, Xu C, Zhao H, Zhou Y, Wang Y, Yang M, Chen X, Chen J
Journal of molecular cell biology 2020 Jul 27;12(12):933-945
Journal of molecular cell biology 2020 Jul 27;12(12):933-945
FLIM-FRET-Based Structural Characterization of a Class-A GPCR Dimer in the Cell Membrane.
Yang J, Gong Z, Lu YB, Xu CJ, Wei TF, Yang MS, Zhan TW, Yang YH, Lin L, Liu J, Tang C, Zhang WP
Journal of molecular biology 2020 Jul 24;432(16):4596-4611
Journal of molecular biology 2020 Jul 24;432(16):4596-4611
Glucosylation by the Legionella Effector SetA Promotes the Nuclear Localization of the Transcription Factor TFEB.
Beck WHJ, Kim D, Das J, Yu H, Smolka MB, Mao Y
iScience 2020 Jul 24;23(7):101300
iScience 2020 Jul 24;23(7):101300
LINC00266-1/miR-548c-3p/SMAD2 feedback loop stimulates the development of osteosarcoma.
Zheng S, Wan L, Ge D, Jiang F, Qian Z, Tang J, Yang J, Yao Y, Yan J, Zhao L, Li H, Yang L
Cell death & disease 2020 Jul 24;11(7):576
Cell death & disease 2020 Jul 24;11(7):576
Ddx56 maintains proliferation of mouse embryonic stem cells via ribosome assembly and interaction with the Oct4/Sox2 complex.
Wang J, Liu J, Ye M, Liu F, Wu S, Huang J, Shi G
Stem cell research & therapy 2020 Jul 23;11(1):314
Stem cell research & therapy 2020 Jul 23;11(1):314
Dopaminergic neurodegeneration induced by Parkinson's disease-linked G2019S LRRK2 is dependent on kinase and GTPase activity.
Nguyen APT, Tsika E, Kelly K, Levine N, Chen X, West AB, Boularand S, Barneoud P, Moore DJ
Proceedings of the National Academy of Sciences of the United States of America 2020 Jul 21;117(29):17296-17307
Proceedings of the National Academy of Sciences of the United States of America 2020 Jul 21;117(29):17296-17307
The food contaminant deoxynivalenol provokes metabolic impairments resulting in non-alcoholic fatty liver (NAFL) in mice.
Barbouche R, Gaigé S, Airault C, Poirot K, Dallaporta M, Troadec JD, Abysique A
Scientific reports 2020 Jul 21;10(1):12072
Scientific reports 2020 Jul 21;10(1):12072
CTCF promotes colorectal cancer cell proliferation and chemotherapy resistance to 5-FU via the P53-Hedgehog axis.
Lai Q, Li Q, He C, Fang Y, Lin S, Cai J, Ding J, Zhong Q, Zhang Y, Wu C, Wang X, He J, Liu Y, Yan Q, Li A, Liu S
Aging 2020 Jul 20;12(16):16270-16293
Aging 2020 Jul 20;12(16):16270-16293
Leukemogenic Chromatin Alterations Promote AML Leukemia Stem Cells via a KDM4C-ALKBH5-AXL Signaling Axis.
Wang J, Li Y, Wang P, Han G, Zhang T, Chang J, Yin R, Shan Y, Wen J, Xie X, Feng M, Wang Q, Hu J, Cheng Y, Zhang T, Li Y, Gao Z, Guo C, Wang J, Liang J, Cui M, Gao K, Chai J, Liu W, Cheng H, Li L, Zhou F, Liu L, Luo Y, Li S, Zhang H
Cell stem cell 2020 Jul 2;27(1):81-97.e8
Cell stem cell 2020 Jul 2;27(1):81-97.e8
SIRT1 alleviates high-magnitude compression-induced senescence in nucleus pulposus cells via PINK1-dependent mitophagy.
Wang Y, Wang H, Zhuo Y, Hu Y, Zhang Z, Ye J, Liu L, Luo L, Zhao C, Zhou Q, Li P
Aging 2020 Jul 18;12(16):16126-16141
Aging 2020 Jul 18;12(16):16126-16141
The urea transporter UT-A1 plays a predominant role in a urea-dependent urine-concentrating mechanism.
Geng X, Zhang S, He J, Ma A, Li Y, Li M, Zhou H, Chen G, Yang B
The Journal of biological chemistry 2020 Jul 17;295(29):9893-9900
The Journal of biological chemistry 2020 Jul 17;295(29):9893-9900
A Nimbolide-Based Kinase Degrader Preferentially Degrades Oncogenic BCR-ABL.
Tong B, Spradlin JN, Novaes LFT, Zhang E, Hu X, Moeller M, Brittain SM, McGregor LM, McKenna JM, Tallarico JA, Schirle M, Maimone TJ, Nomura DK
ACS chemical biology 2020 Jul 17;15(7):1788-1794
ACS chemical biology 2020 Jul 17;15(7):1788-1794
RNF126-Mediated Reubiquitination Is Required for Proteasomal Degradation of p97-Extracted Membrane Proteins.
Hu X, Wang L, Wang Y, Ji J, Li J, Wang Z, Li C, Zhang Y, Zhang ZR
Molecular cell 2020 Jul 16;79(2):320-331.e9
Molecular cell 2020 Jul 16;79(2):320-331.e9
Intracellular expression of arginine deiminase activates the mitochondrial apoptosis pathway by inhibiting cytosolic ferritin and inducing chromatin autophagy.
Feng Q, Bian X, Liu X, Wang Y, Zhou H, Ma X, Quan C, Yao Y, Zheng Z
BMC cancer 2020 Jul 16;20(1):665
BMC cancer 2020 Jul 16;20(1):665
BMMSC-sEV-derived miR-328a-3p promotes ECM remodeling of damaged urethral sphincters via the Sirt7/TGFβ signaling pathway.
Zhang H, Huang J, Liu J, Li Y, Gao Y
Stem cell research & therapy 2020 Jul 16;11(1):286
Stem cell research & therapy 2020 Jul 16;11(1):286
Nedd8-activating enzyme inhibitor MLN4924 (Pevonedistat), inhibits miR-1303 to suppress human breast cancer cell proliferation via targeting p27(Kip1).
Chen Y, Du M, Yusuying S, Liu W, Tan Y, Xie P
Experimental cell research 2020 Jul 15;392(2):112038
Experimental cell research 2020 Jul 15;392(2):112038
Effective-component compatibility of Bufei Yishen formula II inhibits mucus hypersecretion of chronic obstructive pulmonary disease rats by regulating EGFR/PI3K/mTOR signaling.
Li J, Ma J, Tian Y, Zhao P, Liu X, Dong H, Zheng W, Feng S, Zhang L, Wu M, Zhu L, Liu S, Zhao D
Journal of ethnopharmacology 2020 Jul 15;257:112796
Journal of ethnopharmacology 2020 Jul 15;257:112796
ZIC2 is downregulated and represses tumor growth via the regulation of STAT3 in breast cancer.
Liu ZH, Chen ML, Zhang Q, Zhang Y, An X, Luo YL, Liu XM, Liu SX, Liu Q, Yang T, Liu YM, Liu BL, Zhou AJ, Li MZ, Liu YJ, Liu ZX, Zhong Q
International journal of cancer 2020 Jul 15;147(2):505-518
International journal of cancer 2020 Jul 15;147(2):505-518
Excessive Polyamine Generation in Keratinocytes Promotes Self-RNA Sensing by Dendritic Cells in Psoriasis.
Lou F, Sun Y, Xu Z, Niu L, Wang Z, Deng S, Liu Z, Zhou H, Bai J, Yin Q, Cai X, Sun L, Wang H, Li Q, Wu Z, Chen X, Gu J, Shi YL, Tao W, Ginhoux F, Wang H
Immunity 2020 Jul 14;53(1):204-216.e10
Immunity 2020 Jul 14;53(1):204-216.e10
Circular RNA CDR1as Exerts Oncogenic Properties Partially through Regulating MicroRNA 641 in Cholangiocarcinoma.
Li D, Tang Z, Gao Z, Shen P, Liu Z, Dang X
Molecular and cellular biology 2020 Jul 14;40(15)
Molecular and cellular biology 2020 Jul 14;40(15)
CPEB3 inhibits epithelial-mesenchymal transition by disrupting the crosstalk between colorectal cancer cells and tumor-associated macrophages via IL-6R/STAT3 signaling.
Zhong Q, Fang Y, Lai Q, Wang S, He C, Li A, Liu S, Yan Q
Journal of experimental & clinical cancer research : CR 2020 Jul 11;39(1):132
Journal of experimental & clinical cancer research : CR 2020 Jul 11;39(1):132
Synaptopodin-2 promotes hepatocellular carcinoma metastasis via calcineurin-induced nuclear-cytoplasmic translocation.
Gao J, Zhang HP, Sun YH, Guo WZ, Li J, Tang HW, Guo DF, Zhang JK, Shi XY, Yu DS, Zhang XD, Wen PH, Shi JH, Zhang SJ
Cancer letters 2020 Jul 10;482:8-18
Cancer letters 2020 Jul 10;482:8-18
ETV4 is a theranostic target in clear cell renal cell carcinoma that promotes metastasis by activating the pro-metastatic gene FOSL1 in a PI3K-AKT dependent manner.
Xu L, Hu H, Zheng LS, Wang MY, Mei Y, Peng LX, Qiang YY, Li CZ, Meng DF, Wang MD, Liu ZJ, Li XJ, Huang BJ, Qian CN
Cancer letters 2020 Jul 10;482:74-89
Cancer letters 2020 Jul 10;482:74-89
MiR-920 promotes osteogenic differentiation of human bone mesenchymal stem cells by targeting HOXA7.
Zha JP, Wang XQ, Di J
Journal of orthopaedic surgery and research 2020 Jul 10;15(1):254
Journal of orthopaedic surgery and research 2020 Jul 10;15(1):254
TCF7L2 rs290487 C allele aberrantly enhances hepatic gluconeogenesis through allele-specific changes in transcription and chromatin binding.
Zhang X, Ye P, Huang H, Wang B, Dong F, Ling Q
Aging 2020 Jul 10;12(13):13365-13387
Aging 2020 Jul 10;12(13):13365-13387
GABRG2 Deletion Linked to Genetic Epilepsy with Febrile Seizures Plus Affects the Expression of GABA(A) Receptor Subunits and Other Genes at Different Temperatures.
Li X, Guo S, Liu K, Zhang C, Chang H, Yang W, Rong S, Hu Q, Cui J, Wang F, Sun T
Neuroscience 2020 Jul 1;438:116-136
Neuroscience 2020 Jul 1;438:116-136
miR-744-5p mediates lncRNA HOTTIP to regulate the proliferation and apoptosis of papillary thyroid carcinoma cells.
Yuan Q, Fan Y, Liu Z, Wang X, Jia M, Geng Z, Zheng J, Lu X
Experimental cell research 2020 Jul 1;392(1):112024
Experimental cell research 2020 Jul 1;392(1):112024
Erythropoietin-producing hepatocellular receptor A7 restrains estrogen negative feedback of luteinizing hormone via ephrin A5 in the hypothalamus of female rats.
Li S, Zhai J, Xu B, Liu J, Chu W, Wang D, Geng X, Chen ZJ, Du Y
American journal of physiology. Endocrinology and metabolism 2020 Jul 1;319(1):E81-E90
American journal of physiology. Endocrinology and metabolism 2020 Jul 1;319(1):E81-E90
Circulating extracellular vesicles from patients with valvular heart disease induce neutrophil chemotaxis via FOXO3a and the inhibiting role of dexmedetomidine.
Yuan HX, Chen CY, Li YQ, Ning DS, Li Y, Chen YT, Li SX, Fu MX, Li XD, Ma J, Jian YP, Liu DH, Mo ZW, Peng YM, Xu KQ, Ou ZJ, Ou JS
American journal of physiology. Endocrinology and metabolism 2020 Jul 1;319(1):E217-E231
American journal of physiology. Endocrinology and metabolism 2020 Jul 1;319(1):E217-E231
A role of the frontotemporal lobar degeneration risk factor TMEM106B in myelination.
Feng T, Sheng RR, Solé-Domènech S, Ullah M, Zhou X, Mendoza CS, Enriquez LCM, Katz II, Paushter DH, Sullivan PM, Wu X, Maxfield FR, Hu F
Brain : a journal of neurology 2020 Jul 1;143(7):2255-2271
Brain : a journal of neurology 2020 Jul 1;143(7):2255-2271
LncRNA MBNL1-AS1 represses cell proliferation and enhances cell apoptosis via targeting miR-135a-5p/PHLPP2/FOXO1 axis in bladder cancer.
Wei X, Yang X, Wang B, Yang Y, Fang Z, Yi C, Shi L, Song D
Cancer medicine 2020 Jan;9(2):724-736
Cancer medicine 2020 Jan;9(2):724-736
Microglial activation contributes to depressive-like behavior in dopamine D3 receptor knockout mice.
Wang J, Lai S, Li G, Zhou T, Wang B, Cao F, Chen T, Zhang X, Chen Y
Brain, behavior, and immunity 2020 Jan;83:226-238
Brain, behavior, and immunity 2020 Jan;83:226-238
CHK2-FOXK axis promotes transcriptional control of autophagy programs.
Chen Y, Wu J, Liang G, Geng G, Zhao F, Yin P, Nowsheen S, Wu C, Li Y, Li L, Kim W, Zhou Q, Huang J, Liu J, Zhang C, Guo G, Deng M, Tu X, Gao X, Liu Z, Chen Y, Lou Z, Luo K, Yuan J
Science advances 2020 Jan;6(1):eaax5819
Science advances 2020 Jan;6(1):eaax5819
MiR-let-7d-3p regulates IL-17 expression through targeting AKT1/mTOR signaling in CD4(+) T cells.
Wang J, Wang X, Wang L, Sun C, Xie C, Li Z
In vitro cellular & developmental biology. Animal 2020 Jan;56(1):67-74
In vitro cellular & developmental biology. Animal 2020 Jan;56(1):67-74
PRRX1-induced epithelial-to-mesenchymal transition in salivary adenoid cystic carcinoma activates the metabolic reprogramming of free fatty acids to promote invasion and metastasis.
Jiang YP, Tang YL, Wang SS, Wu JS, Zhang M, Pang X, Wu JB, Chen Y, Tang YJ, Liang XH
Cell proliferation 2020 Jan;53(1):e12705
Cell proliferation 2020 Jan;53(1):e12705
SIRT3 promotes the invasion and metastasis of cervical cancer cells by regulating fatty acid synthase.
Xu LX, Hao LJ, Ma JQ, Liu JK, Hasim A
Molecular and cellular biochemistry 2020 Jan;464(1-2):11-20
Molecular and cellular biochemistry 2020 Jan;464(1-2):11-20
The aqueous extract of Gentianella acuta improves isoproterenol‑induced myocardial fibrosis via inhibition of the TGF‑β1/Smads signaling pathway.
Yang HX, Xu GR, Zhang C, Sun JH, Zhang Y, Song JN, Li YF, Liu Y, Li AY
International journal of molecular medicine 2020 Jan;45(1):223-233
International journal of molecular medicine 2020 Jan;45(1):223-233
Metformin facilitates the proliferation, migration, and osteogenic differentiation of periodontal ligament stem cells in vitro.
Zhang R, Liang Q, Kang W, Ge S
Cell biology international 2020 Jan;44(1):70-79
Cell biology international 2020 Jan;44(1):70-79
RNA-binding motif protein 10 induces apoptosis and suppresses proliferation by activating p53.
Jung JH, Lee H, Cao B, Liao P, Zeng SX, Lu H
Oncogene 2020 Jan;39(5):1031-1040
Oncogene 2020 Jan;39(5):1031-1040
Dichloroacetate restores colorectal cancer chemosensitivity through the p53/miR-149-3p/PDK2-mediated glucose metabolic pathway.
Liang Y, Hou L, Li L, Li L, Zhu L, Wang Y, Huang X, Hou Y, Zhu D, Zou H, Gu Y, Weng X, Wang Y, Li Y, Wu T, Yao M, Gross I, Gaiddon C, Luo M, Wang J, Meng X
Oncogene 2020 Jan;39(2):469-485
Oncogene 2020 Jan;39(2):469-485
Autophagy and Ubiquitin-Proteasome System Coordinate to Regulate the Protein Quality Control of Neurodegenerative Disease-Associated DCTN1.
Wang N, Ma Q, Peng P, Yu Y, Xu S, Wang G, Ying Z, Wang H
Neurotoxicity research 2020 Jan;37(1):48-57
Neurotoxicity research 2020 Jan;37(1):48-57
Fabrication of porous bovine pericardium scaffolds incorporated with bFGF for tissue engineering applications.
Liu X, Wu H, Lu F, Li Q, Xu Z
Xenotransplantation 2020 Jan;27(1):e12568
Xenotransplantation 2020 Jan;27(1):e12568
MiR-146a down-regulates inflammatory response by targeting TLR3 and TRAF6 in Coxsackievirus B infection.
Fei Y, Chaulagain A, Wang T, Chen Y, Liu J, Yi M, Wang Y, Huang Y, Lin L, Chen S, Xu W, Tong L, Wu X, Zhao D, Zhang F, Zhao W, Zhong Z
RNA (New York, N.Y.) 2020 Jan;26(1):91-100
RNA (New York, N.Y.) 2020 Jan;26(1):91-100
In utero hypoxia altered Ang II-induced contraction via PKCβ in fetal cerebral arteries.
Su H, Chen X, Zhang Y, Qi L, He Y, Lv J, Zhang Y, Li X, Tang J, Xu Z
The Journal of endocrinology 2020 Jan;244(1):213-222
The Journal of endocrinology 2020 Jan;244(1):213-222
Hic-5 deficiency protects cerulein-induced chronic pancreatitis via down-regulation of the NF-κB (p65)/IL-6 signalling pathway.
Chen H, Tan P, Qian B, Du Y, Wang A, Shi H, Huang Z, Huang S, Liang T, Fu W
Journal of cellular and molecular medicine 2020 Jan;24(2):1488-1503
Journal of cellular and molecular medicine 2020 Jan;24(2):1488-1503
MicroRNA-29b-3p suppresses oral squamous cell carcinoma cell migration and invasion via IL32/AKT signalling pathway.
He J, Ye W, Kou N, Chen K, Cui B, Zhang X, Hu S, Liu T, Kang L, Li X
Journal of cellular and molecular medicine 2020 Jan;24(1):841-849
Journal of cellular and molecular medicine 2020 Jan;24(1):841-849
Protective mechanism of SIRT1 on Hcy-induced atrial fibrosis mediated by TRPC3.
Han L, Tang Y, Li S, Wu Y, Chen X, Wu Q, Hong K, Li J
Journal of cellular and molecular medicine 2020 Jan;24(1):488-510
Journal of cellular and molecular medicine 2020 Jan;24(1):488-510
Long noncoding RNA MAGI1-IT1 regulates cardiac hypertrophy by modulating miR-302e/DKK1/Wnt/beta-catenin signaling pathway.
Zhang Q, Wang F, Wang F, Wu N
Journal of cellular physiology 2020 Jan;235(1):245-253
Journal of cellular physiology 2020 Jan;235(1):245-253
Targeting the WEE1 kinase strengthens the antitumor activity of imatinib via promoting KIT autophagic degradation in gastrointestinal stromal tumors.
Liu W, Zeng X, Yin Y, Li C, Yang W, Wan W, Shi L, Wang G, Tao K, Zhang P
Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association 2020 Jan;23(1):39-51
Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association 2020 Jan;23(1):39-51
Exome sequencing revealed Notch ligand JAG1 as a novel candidate gene for familial exudative vitreoretinopathy.
Zhang L, Zhang X, Xu H, Huang L, Zhang S, Liu W, Yang Y, Fei P, Li S, Yang M, Zhao P, Zhu X, Yang Z
Genetics in medicine : official journal of the American College of Medical Genetics 2020 Jan;22(1):77-84
Genetics in medicine : official journal of the American College of Medical Genetics 2020 Jan;22(1):77-84
Activity and mechanism of flavokawain A in inhibiting P-glycoprotein expression in paclitaxel resistance of lung cancer.
Li J, Zheng L, Yan M, Wu J, Liu Y, Tian X, Jiang W, Zhang L, Wang R
Oncology letters 2020 Jan;19(1):379-387
Oncology letters 2020 Jan;19(1):379-387
Receptor tyrosine kinase inhibitors block proliferation of TGEV mainly through p38 mitogen-activated protein kinase pathways.
Dong W, Xie W, Liu Y, Sui B, Zhang H, Liu L, Tan Y, Tong X, Fu ZF, Yin P, Fang L, Peng G
Antiviral research 2020 Jan;173:104651
Antiviral research 2020 Jan;173:104651
Functional heritage: the evolution of chimeric RNA into a gene.
Wu H, Singh S, Shi X, Xie Z, Lin E, Li X, Li H
RNA biology 2020 Jan;17(1):125-134
RNA biology 2020 Jan;17(1):125-134
Activation of PPARA-mediated autophagy reduces Alzheimer disease-like pathology and cognitive decline in a murine model.
Luo R, Su LY, Li G, Yang J, Liu Q, Yang LX, Zhang DF, Zhou H, Xu M, Fan Y, Li J, Yao YG
Autophagy 2020 Jan;16(1):52-69
Autophagy 2020 Jan;16(1):52-69
FGF9 knockout in GABAergic neurons induces apoptosis and inflammation via the Fas/caspase-3 pathway in the cerebellum of mice.
Guo M, Chen H, Duan W, Li Z, Li Y, Ma Y, Xu X, Yi L, Bi Y, Liu Y, Zhang J, Li C
Brain research bulletin 2020 Jan;154:91-101
Brain research bulletin 2020 Jan;154:91-101
Alpha-hemolysin of uropathogenic Escherichia coli induces GM-CSF-mediated acute kidney injury.
Wang C, Li Q, Lv J, Sun X, Cao Y, Yu K, Miao C, Zhang ZS, Yao Z, Wang Q
Mucosal immunology 2020 Jan;13(1):22-33
Mucosal immunology 2020 Jan;13(1):22-33
Osthole inhibits cell proliferation by regulating the TGF-β1/Smad/p38 signaling pathways in pulmonary arterial smooth muscle cells.
Yue Y, Li YQ, Fu S, Wu YT, Zhu L, Hua L, Lv JY, Li YL, Yang DL
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Jan;121:109640
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Jan;121:109640
Long noncoding RNA CASC21 exerts an oncogenic role in colorectal cancer through regulating miR-7-5p/YAP1 axis.
Zheng Y, Nie P, Xu S
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Jan;121:109628
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Jan;121:109628
Convallatoxin induces HaCaT cell necroptosis and ameliorates skin lesions in psoriasis-like mouse models.
Jiang BW, Zhang WJ, Wang Y, Tan LP, Bao YL, Song ZB, Yu CL, Wang SY, Liu L, Li YX
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Jan;121:109615
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Jan;121:109615
Involvement of the p38 MAPK-pHsp27 pathway in vascular hyporeactivity induced by obstructive jaundice in rats.
Di HT, Wu XZ, Wang HQ, Chen M, Kong EL, Yu WF, Wu FX
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Jan;121:109304
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Jan;121:109304
Resveratrol induces depletion of TRAF6 and suppresses prostate cancer cell proliferation and migration.
Khusbu FY, Zhou X, Roy M, Chen FZ, Cao Q, Chen HC
The international journal of biochemistry & cell biology 2020 Jan;118:105644
The international journal of biochemistry & cell biology 2020 Jan;118:105644
Anti-inflammation effects of injectable platelet-rich fibrin via macrophages and dendritic cells.
Zhang J, Yin C, Zhao Q, Zhao Z, Wang J, Miron RJ, Zhang Y
Journal of biomedical materials research. Part A 2020 Jan;108(1):61-68
Journal of biomedical materials research. Part A 2020 Jan;108(1):61-68
Overexpression of human wtTDP-43 causes impairment in hippocampal plasticity and behavioral deficits in CAMKII-tTa transgenic mouse model.
Quadri Z, Johnson N, Zamudio F, Miller A, Peters M, Smeltzer S, Hunt JB Jr, Housley SB, Brown B, Kraner S, Norris CM, Nash K, Weeber E, Lee DC, Selenica MB
Molecular and cellular neurosciences 2020 Jan;102:103418
Molecular and cellular neurosciences 2020 Jan;102:103418
Tamoxifen induces fatty liver disease in breast cancer through the MAPK8/FoxO pathway.
Gong L, Tang H, Luo Z, Sun X, Tan X, Xie L, Lei Y, Cai M, He C, Ma J, Han S
Clinical and translational medicine 2020 Jan;10(1):137-150
Clinical and translational medicine 2020 Jan;10(1):137-150
Decreased DHRS2 expression is associated with HDACi resistance and poor prognosis in ovarian cancer.
Han Y, Wang Z, Sun S, Zhang Z, Liu J, Jin X, Wu P, Ji T, Ding W, Wang B, Gao Q
Epigenetics 2020 Jan-Feb;15(1-2):122-133
Epigenetics 2020 Jan-Feb;15(1-2):122-133
SLC6A8 Knockdown Suppresses the Invasion and Migration of Human Hepatocellular Carcinoma Huh-7 and Hep3B Cells.
Yuan L, Wu XJ, Li WC, Zhuo C, Xu Z, Tan C, Ma R, Wang J, Pu J
Technology in cancer research & treatment 2020 Jan-Dec;19:1533033820983029
Technology in cancer research & treatment 2020 Jan-Dec;19:1533033820983029
Desloratadine, a Novel Antigrowth Reagent for Bladder Cancer.
Ma J, Qi J, Li S, Zhang C, Wang H, Shao L, Yuan X, Sha Q
Technology in cancer research & treatment 2020 Jan-Dec;19:1533033820926591
Technology in cancer research & treatment 2020 Jan-Dec;19:1533033820926591
c-Abl-p38α signaling pathway mediates dopamine neuron loss in trigeminal neuralgia.
Fu J, Mu G, Qiu L, Zhao J, Ou C
Molecular pain 2020 Jan-Dec;16:1744806920930855
Molecular pain 2020 Jan-Dec;16:1744806920930855
Satellite glial cells in sensory ganglia express functional transient receptor potential ankyrin 1 that is sensitized in neuropathic and inflammatory pain.
Shin SM, Itson-Zoske B, Cai Y, Qiu C, Pan B, Stucky CL, Hogan QH, Yu H
Molecular pain 2020 Jan-Dec;16:1744806920925425
Molecular pain 2020 Jan-Dec;16:1744806920925425
Chemokine receptor CXCR4 activates the RhoA/ROCK2 pathway in spinal neurons that induces bone cancer pain.
Xu H, Peng C, Chen XT, Yao YY, Chen LP, Yin Q, Shen W
Molecular pain 2020 Jan-Dec;16:1744806920919568
Molecular pain 2020 Jan-Dec;16:1744806920919568
Scorpion alleviates bone cancer pain through inhibition of bone destruction and glia activation.
Yu J, Luo Y, Jin H, Lv J, Zhou T, Yabasin IB, Wen Q
Molecular pain 2020 Jan-Dec;16:1744806920909993
Molecular pain 2020 Jan-Dec;16:1744806920909993
STAT3 Activation-Induced Fatty Acid Oxidation in CD8(+) T Effector Cells Is Critical for Obesity-Promoted Breast Tumor Growth.
Zhang C, Yue C, Herrmann A, Song J, Egelston C, Wang T, Zhang Z, Li W, Lee H, Aftabizadeh M, Li YJ, Lee PP, Forman S, Somlo G, Chu P, Kruper L, Mortimer J, Hoon DSB, Huang W, Priceman S, Yu H
Cell metabolism 2020 Jan 7;31(1):148-161.e5
Cell metabolism 2020 Jan 7;31(1):148-161.e5
CD2AP links actin to PI3 kinase activity to extend epithelial cell height and constrain cell area.
Wang Y, Brieher WM
The Journal of cell biology 2020 Jan 6;219(1)
The Journal of cell biology 2020 Jan 6;219(1)
A novel IFNα-induced long noncoding RNA negatively regulates immunosuppression by interrupting H3K27 acetylation in head and neck squamous cell carcinoma.
Ma H, Chang H, Yang W, Lu Y, Hu J, Jin S
Molecular cancer 2020 Jan 6;19(1):4
Molecular cancer 2020 Jan 6;19(1):4
An Alu Element Insertion in Intron 1 Results in Aberrant Alternative Splicing of APOBEC3G Pre-mRNA in Northern Pig-Tailed Macaques (Macaca leonina) That May Reduce APOBEC3G-Mediated Hypermutation Pressure on HIV-1.
Zhang XL, Luo MT, Song JH, Pang W, Zheng YT
Journal of virology 2020 Jan 31;94(4)
Journal of virology 2020 Jan 31;94(4)
Isoliquiritigenin inhibits the proliferation, migration and metastasis of Hep3B cells via suppressing cyclin D1 and PI3K/AKT pathway.
Huang Y, Liu C, Zeng WC, Xu GY, Wu JM, Li ZW, Huang XY, Lin RJ, Shi X
Bioscience reports 2020 Jan 31;40(1)
Bioscience reports 2020 Jan 31;40(1)
17β-estradiol binding to ERα promotes the progression of prolactinoma through estrogen-response element-induced CaBP-9k up-regulation.
Liu J, Han H, Lu W, Fan G
Bioscience reports 2020 Jan 31;40(1)
Bioscience reports 2020 Jan 31;40(1)
ADAM12 is A Potential Therapeutic Target Regulated by Hypomethylation in Triple-Negative Breast Cancer.
Mendaza S, Ulazia-Garmendia A, Monreal-Santesteban I, Córdoba A, Azúa YR, Aguiar B, Beloqui R, Armendáriz P, Arriola M, Martín-Sánchez E, Guerrero-Setas D
International journal of molecular sciences 2020 Jan 30;21(3)
International journal of molecular sciences 2020 Jan 30;21(3)
The synthetic cannabinoid dehydroxylcannabidiol restores the function of a major GABA(A) receptor isoform in a cell model of hyperekplexia.
Zou G, Xia J, Han Q, Liu D, Xiong W
The Journal of biological chemistry 2020 Jan 3;295(1):138-145
The Journal of biological chemistry 2020 Jan 3;295(1):138-145
Inhibition of long non-coding RNA metastasis-associated lung adenocarcinoma transcript 1 attenuates high glucose-induced cardiomyocyte apoptosis via regulation of miR-181a-5p.
Cheng Y, Li J, Wang C, Yang H, Wang Y, Zhan T, Guo S, Liang J, Bai Y, Yu J, Liu G
Experimental animals 2020 Jan 29;69(1):34-44
Experimental animals 2020 Jan 29;69(1):34-44
Synthesis, characterization, and antitumor properties of Au(i)-thiourea complexes.
Yu B, Liu Y, Peng X, Hua S, Zhou G, Yan K, Liu Y
Metallomics : integrated biometal science 2020 Jan 29;12(1):104-113
Metallomics : integrated biometal science 2020 Jan 29;12(1):104-113
Hedgehog signaling promotes sorafenib resistance in hepatocellular carcinoma patient-derived organoids.
Wang S, Wang Y, Xun X, Zhang C, Xiang X, Cheng Q, Hu S, Li Z, Zhu J
Journal of experimental & clinical cancer research : CR 2020 Jan 28;39(1):22
Journal of experimental & clinical cancer research : CR 2020 Jan 28;39(1):22
Mechanical force regulation of YAP by F-actin and GPCR revealed by super-resolution imaging.
Gao J, He L, Zhou L, Jing Y, Wang F, Shi Y, Cai M, Sun J, Xu H, Jiang J, Zhang L, Wang H
Nanoscale 2020 Jan 28;12(4):2703-2714
Nanoscale 2020 Jan 28;12(4):2703-2714
Scutellarin inhibition of the rosuvastatin uptake in rat hepatocytes and the competition for organic anion transporting polypeptide 1B1 in HEK293T cells.
Liu J, Guo Y, Liu K, Ye X, Wang F, Xu Y, Xia C
Scientific reports 2020 Jan 28;10(1):1308
Scientific reports 2020 Jan 28;10(1):1308
Proteomic and lipidomic analysis of exosomes derived from ovarian cancer cells and ovarian surface epithelial cells.
Cheng L, Zhang K, Qing Y, Li D, Cui M, Jin P, Xu T
Journal of ovarian research 2020 Jan 22;13(1):9
Journal of ovarian research 2020 Jan 22;13(1):9
Inhibitory Activity of a Scorpion Defensin BmKDfsin3 against Hepatitis C Virus.
Cheng Y, Sun F, Li S, Gao M, Wang L, Sarhan M, Abdel-Rahman MA, Li W, Kwok HF, Wu Y, Cao Z
Antibiotics (Basel, Switzerland) 2020 Jan 17;9(1)
Antibiotics (Basel, Switzerland) 2020 Jan 17;9(1)
Photocrosslinking Activity-Based Probes for Ubiquitin RING E3 Ligases.
Mathur S, Fletcher AJ, Branigan E, Hay RT, Virdee S
Cell chemical biology 2020 Jan 16;27(1):74-82.e6
Cell chemical biology 2020 Jan 16;27(1):74-82.e6
Dysregulation of BDNF/TrkB signaling mediated by NMDAR/Ca(2+)/calpain might contribute to postoperative cognitive dysfunction in aging mice.
Qiu LL, Pan W, Luo D, Zhang GF, Zhou ZQ, Sun XY, Yang JJ, Ji MH
Journal of neuroinflammation 2020 Jan 16;17(1):23
Journal of neuroinflammation 2020 Jan 16;17(1):23
High RhCG expression predicts poor survival and promotes migration and proliferation of gastric cancer via keeping intracellular alkaline.
Chen P, Liu C, Li P, Wang Q, Gao X, Wu H, Huang J
Experimental cell research 2020 Jan 15;386(2):111740
Experimental cell research 2020 Jan 15;386(2):111740
linc01088 promotes cell proliferation by scaffolding EZH2 and repressing p21 in human non-small cell lung cancer.
Liu JQ, Feng YH, Zeng S, Zhong MZ
Life sciences 2020 Jan 15;241:117134
Life sciences 2020 Jan 15;241:117134
Intermittent hypoxia mediated by TSP1 dependent on STAT3 induces cardiac fibroblast activation and cardiac fibrosis.
Bao Q, Zhang B, Suo Y, Liu C, Yang Q, Zhang K, Yuan M, Yuan M, Zhang Y, Li G
eLife 2020 Jan 14;9
eLife 2020 Jan 14;9
Targeting 7-Dehydrocholesterol Reductase Integrates Cholesterol Metabolism and IRF3 Activation to Eliminate Infection.
Xiao J, Li W, Zheng X, Qi L, Wang H, Zhang C, Wan X, Zheng Y, Zhong R, Zhou X, Lu Y, Li Z, Qiu Y, Liu C, Zhang F, Zhang Y, Xu X, Yang Z, Chen H, Zhai Q, Wei B, Wang H
Immunity 2020 Jan 14;52(1):109-122.e6
Immunity 2020 Jan 14;52(1):109-122.e6
Impact of GFRA1 gene reactivation by DNA demethylation on prognosis of patients with metastatic colon cancer.
Ma WR, Xu P, Liu ZJ, Zhou J, Gu LK, Zhang J, Deng DJ
World journal of gastroenterology 2020 Jan 14;26(2):184-198
World journal of gastroenterology 2020 Jan 14;26(2):184-198
Synaptic density marker SV2A is reduced in schizophrenia patients and unaffected by antipsychotics in rats.
Onwordi EC, Halff EF, Whitehurst T, Mansur A, Cotel MC, Wells L, Creeney H, Bonsall D, Rogdaki M, Shatalina E, Reis Marques T, Rabiner EA, Gunn RN, Natesan S, Vernon AC, Howes OD
Nature communications 2020 Jan 14;11(1):246
Nature communications 2020 Jan 14;11(1):246
FHL3 promotes pancreatic cancer invasion and metastasis through preventing the ubiquitination degradation of EMT associated transcription factors.
Li P, Cao G, Zhang Y, Shi J, Cai K, Zhen L, He X, Zhou Y, Li Y, Zhu Y, Xiong M, Wu Y
Aging 2020 Jan 13;12(1):53-69
Aging 2020 Jan 13;12(1):53-69
RETRACTED: Endogenous production of C-C motif chemokine ligand 2 by nasopharyngeal carcinoma cells drives radioresistance-associated metastasis.
Guo SS, Liu R, Wen YF, Liu LT, Yuan L, Li YX, Li Y, Hao WW, Peng JY, Chen DN, Tang QN, Sun XS, Guo L, Mo HY, Qian CN, Zeng MS, Bei JX, Sun SY, Chen QY, Tang LQ, Mai HQ
Cancer letters 2020 Jan 1;468:27-40
Cancer letters 2020 Jan 1;468:27-40
Yap/Taz are required for establishing the cerebellar radial glia scaffold and proper foliation.
Hughes LJ, Park R, Lee MJ, Terry BK, Lee DJ, Kim H, Cho SH, Kim S
Developmental biology 2020 Jan 1;457(1):150-162
Developmental biology 2020 Jan 1;457(1):150-162
Endothelial microvesicles induced by physiological cyclic stretch inhibit ICAM1-Dependent leukocyte adhesion.
Zhuang F, Shi Q, Wang WB, Bao H, Yan J, Gao S, Liu Z, Jiang ZL, Qi YX
Experimental cell research 2020 Jan 1;386(1):111710
Experimental cell research 2020 Jan 1;386(1):111710
miR-181b-5p inhibits endothelial-mesenchymal transition in monocrotaline-induced pulmonary arterial hypertension by targeting endocan and TGFBR1.
Zhao H, Wang Y, Zhang X, Guo Y, Wang X
Toxicology and applied pharmacology 2020 Jan 1;386:114827
Toxicology and applied pharmacology 2020 Jan 1;386:114827
Hepatitis B virus-triggered PTEN/β-catenin/c-Myc signaling enhances PD-L1 expression to promote immune evasion.
Sun Y, Yu M, Qu M, Ma Y, Zheng D, Yue Y, Guo S, Tang L, Li G, Zheng W, Wang M, Guo D, Li C
American journal of physiology. Gastrointestinal and liver physiology 2020 Jan 1;318(1):G162-G173
American journal of physiology. Gastrointestinal and liver physiology 2020 Jan 1;318(1):G162-G173
Role of the autotaxin-lysophosphatidic acid axis in glaucoma, aqueous humor drainage and fibrogenic activity.
Ho LTY, Osterwald A, Ruf I, Hunziker D, Mattei P, Challa P, Vann R, Ullmer C, Rao PV
Biochimica et biophysica acta. Molecular basis of disease 2020 Jan 1;1866(1):165560
Biochimica et biophysica acta. Molecular basis of disease 2020 Jan 1;1866(1):165560
Attenuation of secondary damage and Aβ deposits in the ipsilateral thalamus of dMCAO rats through reduction of cathepsin B by bis(propyl)-cognitin, a multifunctional dimer.
Zuo X, Hu S, Tang Y, Zhan L, Sun W, Zheng J, Han Y, Xu E
Neuropharmacology 2020 Jan 1;162:107786
Neuropharmacology 2020 Jan 1;162:107786
Identification of chemoresistance-related mRNAs based on gemcitabine-resistant pancreatic cancer cell lines.
Zhou J, Zhang L, Zheng H, Ge W, Huang Y, Yan Y, Zhou X, Zhu W, Kong Y, Ding Y, Wang W
Cancer medicine 2020 Feb;9(3):1115-1130
Cancer medicine 2020 Feb;9(3):1115-1130
Interferon gamma inhibits CXCL8-CXCR2 axis mediated tumor-associated macrophages tumor trafficking and enhances anti-PD1 efficacy in pancreatic cancer.
Zhang M, Huang L, Ding G, Huang H, Cao G, Sun X, Lou N, Wei Q, Shen T, Xu X, Cao L, Yan Q
Journal for immunotherapy of cancer 2020 Feb;8(1)
Journal for immunotherapy of cancer 2020 Feb;8(1)
The key role of macrophage depolarization in the treatment of COPD with ergosterol both in vitro and in vivo.
Sun X, Liu Y, Feng X, Li C, Li S, Zhao Z
International immunopharmacology 2020 Feb;79:106086
International immunopharmacology 2020 Feb;79:106086
LL-37 restored glucocorticoid sensitivity impaired by virus dsRNA in lung.
Li K, Tao N, Zheng L, Sun T
International immunopharmacology 2020 Feb;79:106057
International immunopharmacology 2020 Feb;79:106057
Icariside II improves myocardial fibrosis in spontaneously hypertensive rats by inhibiting collagen synthesis.
Fu S, Li Y, Wu Y, Yue Y, Yang D
The Journal of pharmacy and pharmacology 2020 Feb;72(2):227-235
The Journal of pharmacy and pharmacology 2020 Feb;72(2):227-235
Activation of CRHR1 contributes to cerebral endothelial barrier impairment via cPLA(2) phosphorylation in experimental ischemic stroke.
Cao C, Zhou J, Wu X, Qian Y, Hong Y, Mu J, Jin L, Zhu C, Li S
Cellular signalling 2020 Feb;66:109467
Cellular signalling 2020 Feb;66:109467
Alveolar Stretch Activation of Endothelial Piezo1 Protects Adherens Junctions and Lung Vascular Barrier.
Zhong M, Wu W, Kang H, Hong Z, Xiong S, Gao X, Rehman J, Komarova YA, Malik AB
American journal of respiratory cell and molecular biology 2020 Feb;62(2):168-177
American journal of respiratory cell and molecular biology 2020 Feb;62(2):168-177
Long non‑coding RNA CASC2 suppresses pancreatic cancer cell growth and progression by regulating the miR‑24/MUC6 axis.
Xu DF, Wang LS, Zhou JH
International journal of oncology 2020 Feb;56(2):494-507
International journal of oncology 2020 Feb;56(2):494-507
Epiregulin promotes trophoblast epithelial-mesenchymal transition through poFUT1 and O-fucosylation by poFUT1 on uPA.
Cui X, Wang H, Li Y, Chen T, Liu S, Yan Q
Cell proliferation 2020 Feb;53(2):e12745
Cell proliferation 2020 Feb;53(2):e12745
Long noncoding RNA NEAT1 is involved in the protective effect of Klotho on renal tubular epithelial cells in diabetic kidney disease through the ERK1/2 signaling pathway.
Yang YL, Xue M, Jia YJ, Hu F, Zheng ZJ, Wang L, Si ZK, Xue YM
Experimental & molecular medicine 2020 Feb;52(2):266-280
Experimental & molecular medicine 2020 Feb;52(2):266-280
miR-1294 alleviates epithelial-mesenchymal transition by repressing FOXK1 in gastric cancer.
Wang Y, Liu G, Sun S, Qin J
Genes & genomics 2020 Feb;42(2):217-224
Genes & genomics 2020 Feb;42(2):217-224
EPHA2 feedback activation limits the response to PDEδ inhibition in KRAS-dependent cancer cells.
Chen YH, Lv H, Shen N, Wang XM, Tang S, Xiong B, Ding J, Geng MY, Huang M
Acta pharmacologica Sinica 2020 Feb;41(2):270-277
Acta pharmacologica Sinica 2020 Feb;41(2):270-277
A lncRNA coordinates with Ezh2 to inhibit HIF-1α transcription and suppress cancer cell adaption to hypoxia.
Wang X, Wang Y, Li L, Xue X, Xie H, Shi H, Hu Y
Oncogene 2020 Feb;39(9):1860-1874
Oncogene 2020 Feb;39(9):1860-1874
RBBP8/CtIP suppresses P21 expression by interacting with CtBP and BRCA1 in gastric cancer.
Yu Y, Chen L, Zhao G, Li H, Guo Q, Zhu S, Li P, Min L, Zhang S
Oncogene 2020 Feb;39(6):1273-1289
Oncogene 2020 Feb;39(6):1273-1289
Comparative Transcriptome Analysis Reveals Different Host Cell Responses to Acute and Persistent Foot-and-Mouth Disease Virus Infection.
Li J, Han L, Hao Y, Yuan Y, Wang M, Xin X, Wang H, Yu F, Zheng C, Shen C
Virologica Sinica 2020 Feb;35(1):52-63
Virologica Sinica 2020 Feb;35(1):52-63
Histone deacetylase 6 inhibition restores autophagic flux to promote functional recovery after spinal cord injury.
Zheng Z, Zhou Y, Ye L, Lu Q, Zhang K, Zhang J, Xie L, Wu Y, Xu K, Zhang H, Xiao J
Experimental neurology 2020 Feb;324:113138
Experimental neurology 2020 Feb;324:113138
Bisphenol A Exposure Enhances Endometrial Stromal Cell Invasion and Has a Positive Association with Peritoneal Endometriosis.
Wen X, Xiong Y, Jin L, Zhang M, Huang L, Mao Y, Zhou C, Qiao Y, Zhang Y
Reproductive sciences (Thousand Oaks, Calif.) 2020 Feb;27(2):704-712
Reproductive sciences (Thousand Oaks, Calif.) 2020 Feb;27(2):704-712
HSF1 promotes the viability of islet β-cells via upregulating SIRPα expression.
Zhang HM, Yang M, Zhang XY, Tang Y, Wu JL, Huang J
European review for medical and pharmacological sciences 2020 Feb;24(4):1939-1947
European review for medical and pharmacological sciences 2020 Feb;24(4):1939-1947
N-glycosylation of uterine endometrium determines its receptivity.
Yu M, Qin H, Wang H, Liu J, Liu S, Yan Q
Journal of cellular physiology 2020 Feb;235(2):1076-1089
Journal of cellular physiology 2020 Feb;235(2):1076-1089
Protocatechuic Aldehyde Represses Proliferation and Migration of Breast Cancer Cells through Targeting C-terminal Binding Protein 1.
Deng Y, Guo W, Li G, Li S, Li H, Li X, Niu B, Song M, Zhang Y, Xu Z, Li F
Journal of breast cancer 2020 Feb;23(1):20-35
Journal of breast cancer 2020 Feb;23(1):20-35
Chidamide induces necroptosis via regulation of c‑FLIPL expression in Jurkat and HUT‑78 cells.
Chi Z, Gao H, Liu H, Wu B, Zhang B, Gu M, Yang W
Molecular medicine reports 2020 Feb;21(2):936-944
Molecular medicine reports 2020 Feb;21(2):936-944
miR‑337‑3p inhibits gastric tumor metastasis by targeting ARHGAP10.
Wang Z, Yao L, Li Y, Hao B, Wang M, Wang J, Gu W, Zhan H, Liu G, Wu Q
Molecular medicine reports 2020 Feb;21(2):705-719
Molecular medicine reports 2020 Feb;21(2):705-719
HDAC11 promotes meiotic apparatus assembly during mouse oocyte maturation via decreasing H4K16 and α-tubulin acetylation.
Sui L, Zhang S, Huang R, Li Z
Cell cycle (Georgetown, Tex.) 2020 Feb;19(3):354-362
Cell cycle (Georgetown, Tex.) 2020 Feb;19(3):354-362
α-synuclein promotes progression of Parkinson's disease by upregulating autophagy signaling pathway to activate NLRP3 inflammasome.
Wang X, Chi J, Huang D, Ding L, Zhao X, Jiang L, Yu Y, Gao F
Experimental and therapeutic medicine 2020 Feb;19(2):931-938
Experimental and therapeutic medicine 2020 Feb;19(2):931-938
BMP4 induces asymmetric cell division in human glioma stem-like cells.
Koguchi M, Nakahara Y, Ito H, Wakamiya T, Yoshioka F, Ogata A, Inoue K, Masuoka J, Izumi H, Abe T
Oncology letters 2020 Feb;19(2):1247-1254
Oncology letters 2020 Feb;19(2):1247-1254
Maternal exposure to fine particle matters cause autophagy via UPR-mediated PI3K-mTOR pathway in testicular tissue of adult male mice in offspring.
Ren L, Huang J, Wei J, Zang Y, Zhao Y, Wu S, Zhao X, Zhou X, Sun Z, Lu H
Ecotoxicology and environmental safety 2020 Feb;189:109943
Ecotoxicology and environmental safety 2020 Feb;189:109943
Capping Protein Regulator and Myosin 1 Linker 3 Is Required for Tumor Metastasis.
Wang H, Wang C, Peng G, Yu D, Cui XG, Sun YH, Ma X
Molecular cancer research : MCR 2020 Feb;18(2):240-252
Molecular cancer research : MCR 2020 Feb;18(2):240-252
3-Mercaptopyruvate sulfurtransferase supports endothelial cell angiogenesis and bioenergetics.
Abdollahi Govar A, Törő G, Szaniszlo P, Pavlidou A, Bibli SI, Thanki K, Resto VA, Chao C, Hellmich MR, Szabo C, Papapetropoulos A, Módis K
British journal of pharmacology 2020 Feb;177(4):866-883
British journal of pharmacology 2020 Feb;177(4):866-883
Retinoic acid receptor gamma is targeted by microRNA-124 and inhibits neurite outgrowth.
Su X, Gu X, Zhang Z, Li W, Wang X
Neuropharmacology 2020 Feb;163:107657
Neuropharmacology 2020 Feb;163:107657
Proteomics profiling of epithelium-derived exosomes from nasal polyps revealed signaling functions affecting cellular proliferation.
Zhou M, Tan KS, Guan WJ, Jiang LJ, Deng J, Gao WX, Lee YM, Xu ZF, Luo X, Liu C, Shi JB, Lai Y
Respiratory medicine 2020 Feb;162:105871
Respiratory medicine 2020 Feb;162:105871
Arfgef1 haploinsufficiency in mice alters neuronal endosome composition and decreases membrane surface postsynaptic GABA(A) receptors.
Teoh J, Subramanian N, Pero ME, Bartolini F, Amador A, Kanber A, Williams D, Petri S, Yang M, Allen AS, Beal J, Haut SR, Frankel WN
Neurobiology of disease 2020 Feb;134:104632
Neurobiology of disease 2020 Feb;134:104632
The role of invariant natural killer T cells in experimental xenobiotic-induced cholestatic hepatotoxicity.
Nong C, Zou M, Xue R, Bai L, Liu L, Jiang Z, Sun L, Huang X, Zhang L, Wang X
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Feb;122:109579
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Feb;122:109579
lncRNA SNHG3 facilitates acute myeloid leukemia cell growth via the regulation of miR-758-3p/SRGN axis.
Peng L, Zhang Y, Xin H
Journal of cellular biochemistry 2020 Feb;121(2):1023-1031
Journal of cellular biochemistry 2020 Feb;121(2):1023-1031
A risk prediction model of DNA methylation improves prognosis evaluation and indicates gene targets in prostate cancer.
Zhang E, Hou X, Hou B, Zhang M, Song Y
Epigenomics 2020 Feb;12(4):333-352
Epigenomics 2020 Feb;12(4):333-352
Ubiquitination of NOTCH2 by DTX3 suppresses the proliferation and migration of human esophageal carcinoma.
Ding XY, Hu HY, Huang KN, Wei RQ, Min J, Qi C, Tang H, Qin X
Cancer science 2020 Feb;111(2):489-501
Cancer science 2020 Feb;111(2):489-501
3-O-Acetyl-11-keto- β -boswellic acid ameliorated aberrant metabolic landscape and inhibited autophagy in glioblastoma.
Li W, Ren L, Zheng X, Liu J, Wang J, Ji T, Du G
Acta pharmaceutica Sinica. B 2020 Feb;10(2):301-312
Acta pharmaceutica Sinica. B 2020 Feb;10(2):301-312
FAM172A inhibits EMT in pancreatic cancer via ERK-MAPK signaling.
Chen Y, Liu P, Shen D, Liu H, Xu L, Wang J, Shen D, Sun H, Wu H
Biology open 2020 Feb 7;9(2)
Biology open 2020 Feb 7;9(2)
Systematic Comparison of Label-Free, SILAC, and TMT Techniques to Study Early Adaption toward Inhibition of EGFR Signaling in the Colorectal Cancer Cell Line DiFi.
Stepath M, Zülch B, Maghnouj A, Schork K, Turewicz M, Eisenacher M, Hahn S, Sitek B, Bracht T
Journal of proteome research 2020 Feb 7;19(2):926-937
Journal of proteome research 2020 Feb 7;19(2):926-937
Extracellular nanofiber-orchestrated cytoskeletal reorganization and mediated directional migration of cancer cells.
Wang Y, Gong J, Yao Y
Nanoscale 2020 Feb 7;12(5):3183-3193
Nanoscale 2020 Feb 7;12(5):3183-3193
DGCR8/ZFAT-AS1 Promotes CDX2 Transcription in a PRC2 Complex-Dependent Manner to Facilitate the Malignant Biological Behavior of Glioma Cells.
Zhang F, Ruan X, Ma J, Liu X, Zheng J, Liu Y, Liu L, Shen S, Shao L, Wang D, Yang C, Cai H, Li Z, Feng Z, Xue Y
Molecular therapy : the journal of the American Society of Gene Therapy 2020 Feb 5;28(2):613-630
Molecular therapy : the journal of the American Society of Gene Therapy 2020 Feb 5;28(2):613-630
The Fluoro-Thiazolylhydrazone Compound TSC-3C Inhibits Triple Negative Breast Cancer (TNBC) Cell Line Activity by Promoting Apoptosis, Regulating the MAPK Pathway and Inducing Mitochondrial Dysfunction.
Zhang J, Dai J, Zheng Q, Guo S, Yu Y, Hu W, Gao Y, Shi D
International journal of molecular sciences 2020 Feb 4;21(3)
International journal of molecular sciences 2020 Feb 4;21(3)
Protective properties of heme oxygenase-1 expressed in umbilical cord mesenchymal stem cells help restore the ovarian function of premature ovarian failure mice through activating the JNK/Bcl-2 signal pathway-regulated autophagy and upregulating the circulating of CD8(+)CD28(-) T cells.
Yin N, Wu C, Qiu J, Zhang Y, Bo L, Xu Y, Shi M, Zhu S, Yang G, Mao C
Stem cell research & therapy 2020 Feb 4;11(1):49
Stem cell research & therapy 2020 Feb 4;11(1):49
A DNAH17 missense variant causes flagella destabilization and asthenozoospermia.
Zhang B, Ma H, Khan T, Ma A, Li T, Zhang H, Gao J, Zhou J, Li Y, Yu C, Bao J, Ali A, Murtaza G, Yin H, Gao Q, Jiang X, Zhang F, Liu C, Khan I, Zubair M, Hussain HMJ, Khan R, Yousaf A, Yuan L, Lu Y, Xu X, Wang Y, Tao Q, Hao Q, Fang H, Cheng H, Zhang Y, Shi Q
The Journal of experimental medicine 2020 Feb 3;217(2)
The Journal of experimental medicine 2020 Feb 3;217(2)
Mevalonate metabolism-dependent protein geranylgeranylation regulates thymocyte egress.
Du X, Zeng H, Liu S, Guy C, Dhungana Y, Neale G, Bergo MO, Chi H
The Journal of experimental medicine 2020 Feb 3;217(2)
The Journal of experimental medicine 2020 Feb 3;217(2)
Differential effects of Chinese high-fat dietary habits on lipid metabolism: mechanisms and health implications.
Yan S, Zhou H, Liu S, Wang J, Zeng Y, Matias FB, Wen L
Lipids in health and disease 2020 Feb 29;19(1):30
Lipids in health and disease 2020 Feb 29;19(1):30
Downregulation of lung miR-203a-3p expression by high-altitude hypoxia enhances VEGF/Notch signaling.
Cai W, Liu S, Liu Z, Hou S, Lv Q, Cui H, Wang X, Zhang Y, Fan H, Ding H
Aging 2020 Feb 29;12(5):4247-4267
Aging 2020 Feb 29;12(5):4247-4267
SOX2 Represses Hepatitis B Virus Replication by Binding to the Viral EnhII/Cp and Inhibiting the Promoter Activation.
Yang H, Mo J, Xiang Q, Zhao P, Song Y, Yang G, Wu K, Liu Y, Liu W, Wu J
Viruses 2020 Feb 29;12(3)
Viruses 2020 Feb 29;12(3)
FKBP9 promotes the malignant behavior of glioblastoma cells and confers resistance to endoplasmic reticulum stress inducers.
Xu H, Liu P, Yan Y, Fang K, Liang D, Hou X, Zhang X, Wu S, Ma J, Wang R, Li T, Piao H, Meng S
Journal of experimental & clinical cancer research : CR 2020 Feb 28;39(1):44
Journal of experimental & clinical cancer research : CR 2020 Feb 28;39(1):44
Assessment of Prolonged Dengue Virus Infection in Dermal Fibroblasts and Hair-Follicle Dermal Papilla Cells.
Wei KC, Wei WJ, Liu YS, Yen LC, Chang TH
Viruses 2020 Feb 28;12(3)
Viruses 2020 Feb 28;12(3)
Anti-inflammatory effects of Lactobacillus johnsonii L531 in a pig model of Salmonella Infantis infection involves modulation of CCR6(+) T cell responses and ER stress.
Yang GY, Xia B, Su JH, He T, Liu X, Guo L, Zhang S, Zhu YH, Wang JF
Veterinary research 2020 Feb 24;51(1):26
Veterinary research 2020 Feb 24;51(1):26
The behavioural and neuropathologic sexual dimorphism and absence of MIP-3α in tau P301S mouse model of Alzheimer's disease.
Sun Y, Guo Y, Feng X, Jia M, Ai N, Dong Y, Zheng Y, Fu L, Yu B, Zhang H, Wu J, Yu X, Wu H, Kong W
Journal of neuroinflammation 2020 Feb 24;17(1):72
Journal of neuroinflammation 2020 Feb 24;17(1):72
Rumen-Protected Glucose Stimulates the Insulin-Like Growth Factor System and mTOR/AKT Pathway in the Endometrium of Early Postpartum Dairy Cows.
Wang Y, Han X, Tan Z, Kang J, Wang Z
Animals : an open access journal from MDPI 2020 Feb 23;10(2)
Animals : an open access journal from MDPI 2020 Feb 23;10(2)
Structural Basis for Inhibiting Porcine Epidemic Diarrhea Virus Replication with the 3C-Like Protease Inhibitor GC376.
Ye G, Wang X, Tong X, Shi Y, Fu ZF, Peng G
Viruses 2020 Feb 21;12(2)
Viruses 2020 Feb 21;12(2)
Modulation of in vitro Brain Endothelium by Mechanical Trauma: Structural and Functional Restoration by Poloxamer 188.
Inyang E, Abhyankar V, Chen B, Cho M
Scientific reports 2020 Feb 20;10(1):3054
Scientific reports 2020 Feb 20;10(1):3054
A Novel Role for PX, a Structural Protein of Fowl Adenovirus Serotype 4 (FAdV4), as an Apoptosis-Inducer in Leghorn Male Hepatocellular Cell.
Zhao M, Duan X, Wang Y, Gao L, Cao H, Li X, Zheng SJ
Viruses 2020 Feb 18;12(2)
Viruses 2020 Feb 18;12(2)
Targeted overexpression of the long noncoding RNA ODSM can regulate osteoblast function in vitro and in vivo.
Wang Y, Wang K, Zhang L, Tan Y, Hu Z, Dang L, Zhou H, Li G, Wang H, Zhang S, Shi F, Cao X, Zhang G
Cell death & disease 2020 Feb 18;11(2):133
Cell death & disease 2020 Feb 18;11(2):133
Generation of a self-cleaved inducible Cre recombinase for efficient temporal genetic manipulation.
Tian X, He L, Liu K, Pu W, Zhao H, Li Y, Liu X, Tang M, Sun R, Fei J, Ji Y, Qiao Z, Lui KO, Zhou B
The EMBO journal 2020 Feb 17;39(4):e102675
The EMBO journal 2020 Feb 17;39(4):e102675
Overcoming cisplatin resistance by targeting the MTDH-PTEN interaction in ovarian cancer with sera derived from rats exposed to Guizhi Fuling wan extract.
Han L, Cao X, Chen Z, Guo X, Yang L, Zhou Y, Bian H
BMC complementary medicine and therapies 2020 Feb 17;20(1):57
BMC complementary medicine and therapies 2020 Feb 17;20(1):57
Dynasore potentiates c-Met inhibitors against hepatocellular carcinoma through destabilizing c-Met.
Zaky MY, Liu X, Wang T, Wang S, Liu F, Wang D, Wu Y, Zhang Y, Guo D, Sun Q, Li Q, Zhang J, Zhang Y, Dong W, Liu Z, Liu S, Liu H
Archives of biochemistry and biophysics 2020 Feb 15;680:108239
Archives of biochemistry and biophysics 2020 Feb 15;680:108239
GRWD1 promotes cell proliferation and migration in non-small cell lung cancer by activating the Notch pathway.
Wang Q, Ren H, Xu Y, Jiang J, Wudu M, Liu Z, Su H, Jiang X, Zhang Y, Zhang B, Qiu X
Experimental cell research 2020 Feb 15;387(2):111806
Experimental cell research 2020 Feb 15;387(2):111806
Extracellular vesicles transmitted miR-31-5p promotes sorafenib resistance by targeting MLH1 in renal cell carcinoma.
He J, He J, Min L, He Y, Guan H, Wang J, Peng X
International journal of cancer 2020 Feb 15;146(4):1052-1063
International journal of cancer 2020 Feb 15;146(4):1052-1063
Down-regulation of CCR7 via AKT pathway and GATA2 inactivation suppressed trophoblast migration and invasion in recurrent spontaneous abortion†.
Luan X, Li S, Zhao J, Zhai J, Liu X, Chen ZJ, Li W, Du Y
Biology of reproduction 2020 Feb 14;102(2):424-433
Biology of reproduction 2020 Feb 14;102(2):424-433
Entorhinal cortex-based metabolic profiling of chronic restraint stress mice model of depression.
Chen X, Lan T, Wang Y, He Y, Wu Z, Tian Y, Li Y, Bai M, Zhou W, Zhang H, Cheng K, Xie P
Aging 2020 Feb 12;12(3):3042-3052
Aging 2020 Feb 12;12(3):3042-3052
Level of N6-Methyladenosine in Peripheral Blood RNA: A Novel Predictive Biomarker for Gastric Cancer.
Ge L, Zhang N, Chen Z, Song J, Wu Y, Li Z, Chen F, Wu J, Li D, Li J, Wang C, Wang H, Wang J
Clinical chemistry 2020 Feb 1;66(2):342-351
Clinical chemistry 2020 Feb 1;66(2):342-351
Sodium butyrate causes α-synuclein degradation by an Atg5-dependent and PI3K/Akt/mTOR-related autophagy pathway.
Qiao CM, Sun MF, Jia XB, Shi Y, Zhang BP, Zhou ZL, Zhao LP, Cui C, Shen YQ
Experimental cell research 2020 Feb 1;387(1):111772
Experimental cell research 2020 Feb 1;387(1):111772
Nucleostemin promotes hepatocellular carcinoma by regulating the function of STAT3.
Zhang X, Lv J, Luo H, Liu Z, Xu C, Zhou D, Tang L, Zhang Z, Liu J, Xiao M, Yao Y, Qu L, Lu C
Experimental cell research 2020 Feb 1;387(1):111748
Experimental cell research 2020 Feb 1;387(1):111748
Silencing of DsbA-L gene impairs the PPARγ agonist function of improving insulin resistance in a high-glucose cell model.
Zhou X, Li JQ, Wei LJ, He MZ, Jia J, Zhang JY, Wang SS, Feng L
Journal of Zhejiang University. Science. B 2020 Dec.;21(12):990-998
Journal of Zhejiang University. Science. B 2020 Dec.;21(12):990-998
Autotaxin stimulates LPA2 receptor in macrophages and exacerbates dextran sulfate sodium-induced acute colitis.
Wang Z, Shi W, Tian D, Qin H, Vallance BA, Yang H, Yu HB, Yu Q
Journal of molecular medicine (Berlin, Germany) 2020 Dec;98(12):1781-1794
Journal of molecular medicine (Berlin, Germany) 2020 Dec;98(12):1781-1794
Neuron-derived factors negatively modulate ryanodine receptor-mediated calcium release in cultured mouse astrocytes.
Skowrońska K, Kozłowska H, Albrecht J
Cell calcium 2020 Dec;92:102304
Cell calcium 2020 Dec;92:102304
Inhibition of PI3K/Akt/NF-κB signaling by Aloin for ameliorating the progression of osteoarthritis: In vitro and in vivo studies.
Zhang C, Shao Z, Hu X, Chen Z, Li B, Jiang R, Bsoul N, Chen J, Xu C, Gao W
International immunopharmacology 2020 Dec;89(Pt B):107079
International immunopharmacology 2020 Dec;89(Pt B):107079
Protective effect of taraxasterol on ischemia/reperfusion-induced acute kidney injury via inhibition of oxidative stress, inflammation, and apoptosis.
Li C, Zheng Z, Xie Y, Zhu N, Bao J, Yu Q, Zhou Z, Liu J
International immunopharmacology 2020 Dec;89(Pt A):107169
International immunopharmacology 2020 Dec;89(Pt A):107169
Inhibition of PCSK9 potentiates immune checkpoint therapy for cancer.
Liu X, Bao X, Hu M, Chang H, Jiao M, Cheng J, Xie L, Huang Q, Li F, Li CY
Nature 2020 Dec;588(7839):693-698
Nature 2020 Dec;588(7839):693-698
Structure of LRRK2 in Parkinson's disease and model for microtubule interaction.
Deniston CK, Salogiannis J, Mathea S, Snead DM, Lahiri I, Matyszewski M, Donosa O, Watanabe R, Böhning J, Shiau AK, Knapp S, Villa E, Reck-Peterson SL, Leschziner AE
Nature 2020 Dec;588(7837):344-349
Nature 2020 Dec;588(7837):344-349
Hepatoprotective effects of Camellia nitidissima aqueous ethanol extract against CCl(4)-induced acute liver injury in SD rats related to Nrf2 and NF-κB signalling.
Zhang X, Feng J, Su S, Huang L
Pharmaceutical biology 2020 Dec;58(1):239-246
Pharmaceutical biology 2020 Dec;58(1):239-246
Hepatoprotective effect of Xiayuxue decoction ethyl acetate fraction against carbon tetrachloride-induced liver fibrosis in mice via inducing apoptosis and suppressing activation of hepatic stellate cells.
Zhang D, Zhang L, Chen G, Xu Y, Yang H, Xiao Z, Chen J, Mu Y, Zhang H, Liu W, Liu P
Pharmaceutical biology 2020 Dec;58(1):1229-1243
Pharmaceutical biology 2020 Dec;58(1):1229-1243
Hypermethylation-mediated silencing of NDRG4 promotes pancreatic ductal adenocarcinoma by regulating mitochondrial function.
Shi HH, Liu HE, Luo XJ
BMB reports 2020 Dec;53(12):658-663
BMB reports 2020 Dec;53(12):658-663
Hypermethylation-mediated silencing of NDRG4 promotes pancreatic ductal adenocarcinoma by regulating mitochondrial function.
Shi HH, Liu HE, Luo XJ
BMB reports 2020 Dec;53(12):658-663
BMB reports 2020 Dec;53(12):658-663
Anti-tumour activity of zinc ionophore pyrithione in human ovarian cancer cells through inhibition of proliferation and migration and promotion of lysosome-mitochondrial apoptosis.
Chen M, Ding Y, Ke Y, Zeng Y, Liu N, Zhong Y, Hua X, Li Z, Xiong Y, Wu C, Yu H
Artificial cells, nanomedicine, and biotechnology 2020 Dec;48(1):824-833
Artificial cells, nanomedicine, and biotechnology 2020 Dec;48(1):824-833
Circ_0079593 facilitates proliferation, metastasis, glucose metabolism and inhibits apoptosis in melanoma by regulating the miR-516b/GRM3 axis.
Lu J, Li Y
Molecular and cellular biochemistry 2020 Dec;475(1-2):227-237
Molecular and cellular biochemistry 2020 Dec;475(1-2):227-237
Modulation of miRNAs by vitamin C in H2O2‑exposed human umbilical vein endothelial cells.
Wu J, Liang J, Li M, Lin M, Mai L, Huang X, Liang J, Hu Y, Huang Y
International journal of molecular medicine 2020 Dec;46(6):2150-2160
International journal of molecular medicine 2020 Dec;46(6):2150-2160
The protective effects of umbilical cord-derived endothelial colony forming cells on hepatic veno-occlusive disease.
Chen L, Zhang J, Liu X, Yao M, Zhang H
Cell biology international 2020 Dec;44(12):2541-2552
Cell biology international 2020 Dec;44(12):2541-2552
Tumor cell-expressed IL-15Rα drives antagonistic effects on the progression and immune control of gastric cancer and is epigenetically regulated in EBV-positive gastric cancer.
Wei J, Guo C, An X, Miao W, Zhang C, Wang B, Cai W, Li M, Zhang F
Cellular oncology (Dordrecht, Netherlands) 2020 Dec;43(6):1085-1097
Cellular oncology (Dordrecht, Netherlands) 2020 Dec;43(6):1085-1097
Aberrant expression of miRNA-192-5p contributes to N,N-dimethylformamide-induced hepatic apoptosis.
Zhang Z, Zhu W, Liu Z, Liu Y, Chang C, Jiang H, Li R, Xiao Y, Chen W, Hu Q, Wang Q
Journal of applied toxicology : JAT 2020 Dec;40(12):1683-1693
Journal of applied toxicology : JAT 2020 Dec;40(12):1683-1693
Upregulated miR-101 inhibits acute kidney injury-chronic kidney disease transition by regulating epithelial-mesenchymal transition.
Zhao JY, Wang XL, Yang YC, Zhang B, Wu YB
Human & experimental toxicology 2020 Dec;39(12):1628-1638
Human & experimental toxicology 2020 Dec;39(12):1628-1638
The kinesin motor protein KIF4A as a potential therapeutic target in renal cell carcinoma.
Liu G, Lu Y, Li L, Jiang T, Chu S, Hou P, Bai J, Chen M
Investigational new drugs 2020 Dec;38(6):1730-1742
Investigational new drugs 2020 Dec;38(6):1730-1742
Promotion of esophageal adenocarcinoma metastasis via Wnt/ß-catenin signal pathway by sorting nexins 3.
Pan B, Liu L, Hu X, Sun X, Zhu Y, Zhang T, Wei D, Guo Y, Shan J
Journal of gastroenterology and hepatology 2020 Dec;35(12):2131-2139
Journal of gastroenterology and hepatology 2020 Dec;35(12):2131-2139
Chondroitin synthase-3 regulates nucleus pulposus degeneration through actin-induced YAP signaling.
Wei L, Cao P, Xu C, Zhong H, Wang X, Bai M, Hu B, Wang R, Liu N, Tian Y, Chen H, Li J, Yuan W
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Dec;34(12):16581-16600
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Dec;34(12):16581-16600
Polyphyllin I attenuates cognitive impairments and reduces AD-like pathology through CIP2A-PP2A signaling pathway in 3XTg-AD mice.
Zhou Y, Yang D, Chen H, Zheng C, Jiang H, Liu X, Huang X, Ye S, Song S, Jiang N, Zhao Z, Ma S, Ma J, Huang K, Chen C, Fan X, Gong Y, Wang X, Fan J, Liu R, Shentu Y
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Dec;34(12):16414-16431
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Dec;34(12):16414-16431
Cold-induced RNA-binding protein (CIRBP) regulates the expression of Src-associated during mitosis of 68 kDa (Sam68) and extracellular signal-regulated kinases (ERK) during heat stress-induced testicular injury.
Xu C, Ke D, Zou L, Li N, Wang Y, Fan X, Zhu C, Xia W
Reproduction, fertility, and development 2020 Dec;32(18):1357-1364
Reproduction, fertility, and development 2020 Dec;32(18):1357-1364
JMY expression by Sertoli cells contributes to mediating spermatogenesis in mice.
Liu Y, Fan J, Yan Y, Dang X, Zhao R, Xu Y, Ding Z
The FEBS journal 2020 Dec;287(24):5478-5497
The FEBS journal 2020 Dec;287(24):5478-5497
Platelet-derived microvesicles promote endothelial progenitor cell proliferation in intimal injury by delivering TGF-β1.
Yan J, Bao H, Fan YJ, Jiang ZL, Qi YX, Han Y
The FEBS journal 2020 Dec;287(23):5196-5217
The FEBS journal 2020 Dec;287(23):5196-5217
Maresin1 Promotes M2 Macrophage Polarization Through Peroxisome Proliferator-Activated Receptor-γ Activation to Expedite Resolution of Acute Lung Injury.
Qiao N, Lin Y, Wang Z, Chen JY, Ge YY, Yao SL, Gong J
The Journal of surgical research 2020 Dec;256:584-594
The Journal of surgical research 2020 Dec;256:584-594
Inhibition of porcine reproductive and respiratory syndrome virus by PKC inhibitor dequalinium chloride in vitro.
Liu X, Gao L, Zhao Q, Wang X, Yang C, Bi J, Yang R, Jin X, Lan R, Cui R, Wang X, Li W, Wang X, Yang Y, Yu X, Lin Y, Liu J, Yin G
Veterinary microbiology 2020 Dec;251:108913
Veterinary microbiology 2020 Dec;251:108913
Long noncoding RNA XIST regulates cardiomyocyte apoptosis by targeting miR-873-5p/MCL1 axis.
Cai CL, Jin L, Lang XL, Li BL
European review for medical and pharmacological sciences 2020 Dec;24(24):12878-12886
European review for medical and pharmacological sciences 2020 Dec;24(24):12878-12886
IGFBP6 regulates vascular smooth muscle cell proliferation and morphology via cyclin E-CDK2.
Wang Z, Qi Y, Wang R, Wu W, Li Z, Wang M, Liu R, Zhang C, Li W, Wang S
Journal of cellular physiology 2020 Dec;235(12):9538-9556
Journal of cellular physiology 2020 Dec;235(12):9538-9556
The proinflammatory cytokines IL-1β and TNF-α modulate corneal epithelial wound healing through p16(Ink4a) suppressing STAT3 activity.
Wang X, Zhang S, Dong M, Li Y, Zhou Q, Yang L
Journal of cellular physiology 2020 Dec;235(12):10081-10093
Journal of cellular physiology 2020 Dec;235(12):10081-10093
Sulforaphane suppresses polyinosinic‑polycytidylic acid‑stimulated release of cytokines, chemokines and MMPs by human corneal fibroblasts.
Liu P, Liu Y, Zheng H, Zheng X, Yang X, Zhao X, Chen L, Liu Y
Molecular medicine reports 2020 Dec;22(6):5463-5471
Molecular medicine reports 2020 Dec;22(6):5463-5471
miR‑124‑3p regulates angiogenesis in peripheral arterial disease by targeting STAT3.
Shi Y, Xu X, Luan P, Kou W, Li M, Yu Q, Zhuang J, Xu Y, Peng W, Jian W
Molecular medicine reports 2020 Dec;22(6):4890-4898
Molecular medicine reports 2020 Dec;22(6):4890-4898
Demethylation of HACE1 gene promoter by propofol promotes autophagy of human A549 cells.
Li S, Yang H, Zhao M, Gong L, Wang Y, Lv Z, Quan Y, Wang Z
Oncology letters 2020 Dec;20(6):280
Oncology letters 2020 Dec;20(6):280
Long noncoding RNA HAND2-AS1 reduced the viability of hepatocellular carcinoma via targeting microRNA-300/SOCS5 axis.
Bi HQ, Li ZH, Zhang H
Hepatobiliary & pancreatic diseases international : HBPD INT 2020 Dec;19(6):567-574
Hepatobiliary & pancreatic diseases international : HBPD INT 2020 Dec;19(6):567-574
UBR5 over-expression contributes to poor prognosis and tamoxifen resistance of ERa+ breast cancer by stabilizing β-catenin.
Yang Y, Zhao J, Mao Y, Lin G, Li F, Jiang Z
Breast cancer research and treatment 2020 Dec;184(3):699-710
Breast cancer research and treatment 2020 Dec;184(3):699-710
Loss of hepatic aldolase B activates Akt and promotes hepatocellular carcinogenesis by destabilizing the Aldob/Akt/PP2A protein complex.
He X, Li M, Yu H, Liu G, Wang N, Yin C, Tu Q, Narla G, Tao Y, Cheng S, Yin H
PLoS biology 2020 Dec;18(12):e3000803
PLoS biology 2020 Dec;18(12):e3000803
A spirostanol saponin isolated from Tupistra chinensis Baker simultaneously induces apoptosis and autophagy by regulating the JNK pathway in human gastric cancer cells.
Xu J, Wang Z, Huang Y, Wang Y, Xiang L, He X
Steroids 2020 Dec;164:108737
Steroids 2020 Dec;164:108737
LGR4 maintains HGSOC cell epithelial phenotype and stem-like traits.
Wang Z, Yin P, Sun Y, Na L, Gao J, Wang W, Zhao C
Gynecologic oncology 2020 Dec;159(3):839-849
Gynecologic oncology 2020 Dec;159(3):839-849
Pentraxin 3 contributes to neurogenesis after traumatic brain injury in mice.
Zhou C, Chen H, Zheng JF, Guo ZD, Huang ZJ, Wu Y, Zhong JJ, Sun XC, Cheng CJ
Neural regeneration research 2020 Dec;15(12):2318-2326
Neural regeneration research 2020 Dec;15(12):2318-2326
Glycogen synthase kinase-3β inhibition alleviates activation of the NLRP3 inflammasome in myocardial infarction.
Wang S, Su X, Xu L, Chang C, Yao Y, Komal S, Cha X, Zang M, Ouyang X, Zhang L, Han S
Journal of molecular and cellular cardiology 2020 Dec;149:82-94
Journal of molecular and cellular cardiology 2020 Dec;149:82-94
The role of invariant natural killer T cells and associated immunoregulatory factors in triptolide-induced cholestatic liver injury.
Zou M, Nong C, Yu Z, Cai H, Jiang Z, Xue R, Huang X, Sun L, Zhang L, Wang X
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2020 Dec;146:111777
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2020 Dec;146:111777
LINC00673 exerts oncogenic function in cervical cancer by negatively regulating miR-126-5p expression and activates PTEN/PI3K/AKT signaling pathway.
Shi WJ, Liu H, Ge YF, Wu D, Tan YJ, Shen YC, Wang H, Xu H
Cytokine 2020 Dec;136:155286
Cytokine 2020 Dec;136:155286
The effects of cytarabine combined with ginsenoside compound K synergistically induce DNA damage in acute myeloid leukemia cells.
Qi W, Yan X, Xu X, Song B, Sun L, Zhao D, Sun L
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Dec;132:110812
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Dec;132:110812
Gu-Ben-Fang-Xiao attenuates allergic airway inflammation by inhibiting BAFF-mediated B cell activation.
Liang ZQ, Tu PC, Ji JJ, Xing QQ, Zhao X
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Dec;132:110801
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Dec;132:110801
Down-regulation of long noncoding RNA LINC00472 alleviates sepsis-induced acute hepatic injury by regulating miR-373-3p/TRIM8 axis.
Li L, He Y, He XJ, Bi MR, Qi YH, Zhu WW
Experimental and molecular pathology 2020 Dec;117:104562
Experimental and molecular pathology 2020 Dec;117:104562
Enterovirus 71 induces neural cell apoptosis and autophagy through promoting ACOX1 downregulation and ROS generation.
You L, Chen J, Liu W, Xiang Q, Luo Z, Wang W, Xu W, Wu K, Zhang Q, Liu Y, Wu J
Virulence 2020 Dec;11(1):537-553
Virulence 2020 Dec;11(1):537-553
Down-regulation of lncRNA DNAJC3-AS1 inhibits colon cancer via regulating miR-214-3p/LIVIN axis.
Han B, Ge Y, Cui J, Liu B
Bioengineered 2020 Dec;11(1):524-535
Bioengineered 2020 Dec;11(1):524-535
Upregulation of the microRNA rno-miR-146b-5p may be involved in the development of intestinal injury through inhibition of Kruppel-like factor 4 in intestinal sepsis.
Tong L, Tang C, Cai C, Guan X
Bioengineered 2020 Dec;11(1):1334-1349
Bioengineered 2020 Dec;11(1):1334-1349
Cannabinoid receptor subtype influence on neuritogenesis in human SH-SY5Y cells.
Lyons EL, Leone-Kabler S, Kovach AL, Thomas BF, Howlett AC
Molecular and cellular neurosciences 2020 Dec;109:103566
Molecular and cellular neurosciences 2020 Dec;109:103566
Targeted degradation of CD147 proteins in melanoma.
Zhou Z, Long J, Wang Y, Li Y, Zhang X, Tang L, Chang Q, Chen Z, Hu G, Hu S, Li Q, Peng C, Chen X
Bioorganic chemistry 2020 Dec;105:104453
Bioorganic chemistry 2020 Dec;105:104453
Design, synthesis and biological evaluation of novel 1,3,4-thiadiazole derivatives as anti-glioblastoma agents targeting the AKT pathway.
Szeliga M, Karpińska M, Rola R, Niewiadomy A
Bioorganic chemistry 2020 Dec;105:104362
Bioorganic chemistry 2020 Dec;105:104362
Latcripin-7A, derivative of Lentinula edodes C(91-3), reduces migration and induces apoptosis, autophagy, and cell cycle arrest at G(1) phase in breast cancer cells.
Din SRU, Zhong M, Nisar MA, Saleem MZ, Hussain A, Khinsar KH, Alam S, Ayub G, Kanwal S, Li X, Zhang W, Wang X, Ning A, Cao J, Huang M
Applied microbiology and biotechnology 2020 Dec;104(23):10165-10179
Applied microbiology and biotechnology 2020 Dec;104(23):10165-10179
Structural and Functional Characterization of Host FHL1 Protein Interaction with Hypervariable Domain of Chikungunya Virus nsP3 Protein.
Lukash T, Agback T, Dominguez F, Shiliaev N, Meshram C, Frolova EI, Agback P, Frolov I
Journal of virology 2020 Dec 9;95(1)
Journal of virology 2020 Dec 9;95(1)
β-Elemene enhances radiosensitivity in non-small-cell lung cancer by inhibiting epithelial-mesenchymal transition and cancer stem cell traits via Prx-1/NF-kB/iNOS signaling pathway.
Zou K, Li Z, Zhang Y, Mu L, Chen M, Wang R, Deng W, Zou L, Liu J
Aging 2020 Dec 9;13(2):2575-2592
Aging 2020 Dec 9;13(2):2575-2592
FN-EDA mediates angiogenesis of hepatic fibrosis via integrin-VEGFR2 in a CD63 synergetic manner.
Su X, Ma X, Xie X, Wu H, Wang L, Feng Y, Yu Z, Liu C, Qi J, Zhu Q
Cell death discovery 2020 Dec 8;6(1):140
Cell death discovery 2020 Dec 8;6(1):140
Dually regulating the proliferation and the immune microenvironment of melanoma via nanoparticle-delivered siRNA targeting onco-immunologic CD155.
Wang Y, Luo YL, Chen YF, Lu ZD, Wang Y, Czarna A, Shen S, Xu CF, Wang J
Biomaterials science 2020 Dec 7;8(23):6683-6694
Biomaterials science 2020 Dec 7;8(23):6683-6694
Extracellular Cystatin F Is Internalised by Cytotoxic T Lymphocytes and Decreases Their Cytotoxicity.
Prunk M, Perišić Nanut M, Jakoš T, Sabotič J, Švajger U, Kos J
Cancers 2020 Dec 6;12(12)
Cancers 2020 Dec 6;12(12)
The protective effect of 1,25(OH)(2)D(3) against cardiac hypertrophy is mediated by the cyclin-dependent kinase inhibitor p21.
Liu N, Su H, Zhang Y, Kong J
European journal of pharmacology 2020 Dec 5;888:173510
European journal of pharmacology 2020 Dec 5;888:173510
miR-214 Attenuates Aortic Valve Calcification by Regulating Osteogenic Differentiation of Valvular Interstitial Cells.
Li N, Bai Y, Zhou G, Ma Y, Tan M, Qiao F, Li X, Shen M, Song X, Zhao X, Liu X, Xu Z
Molecular therapy. Nucleic acids 2020 Dec 4;22:971-980
Molecular therapy. Nucleic acids 2020 Dec 4;22:971-980
YTHDF1 Facilitates the Progression of Hepatocellular Carcinoma by Promoting FZD5 mRNA Translation in an m6A-Dependent Manner.
Liu X, Qin J, Gao T, Li C, He B, Pan B, Xu X, Chen X, Zeng K, Xu M, Zhu C, Pan Y, Sun H, Sun L, Xu T, Wang S
Molecular therapy. Nucleic acids 2020 Dec 4;22:750-765
Molecular therapy. Nucleic acids 2020 Dec 4;22:750-765
circFN1 Mediates Sorafenib Resistance of Hepatocellular Carcinoma Cells by Sponging miR-1205 and Regulating E2F1 Expression.
Yang C, Dong Z, Hong H, Dai B, Song F, Geng L, Lu J, Yang J, Sui C, Xu M
Molecular therapy. Nucleic acids 2020 Dec 4;22:421-433
Molecular therapy. Nucleic acids 2020 Dec 4;22:421-433
Translatome and Transcriptome Profiling of Hypoxic-Induced Rat Cardiomyocytes.
Shen Z, Zeng L, Zhang Z
Molecular therapy. Nucleic acids 2020 Dec 4;22:1016-1024
Molecular therapy. Nucleic acids 2020 Dec 4;22:1016-1024
SPOCK1/SIX1axis promotes breast cancer progression by activating AKT/mTOR signaling.
Xu M, Zhang X, Zhang S, Piao J, Yang Y, Wang X, Lin Z
Aging 2020 Dec 3;13(1):1032-1050
Aging 2020 Dec 3;13(1):1032-1050
Exogenous hydrogen sulfide inhibits apoptosis by regulating endoplasmic reticulum stress-autophagy axis and improves myocardial reconstruction after acute myocardial infarction.
Li Y, Liu M, Yi J, Song X, Zheng X, Liu D, Wang S, Chu C, Yang J
Acta biochimica et biophysica Sinica 2020 Dec 29;52(12):1325-1336
Acta biochimica et biophysica Sinica 2020 Dec 29;52(12):1325-1336
Overexpression of Mucin 1 Suppresses the Therapeutical Efficacy of Disulfiram against Canine Mammary Tumor.
Zhao Y, Lin Z, Lin Z, Zhou C, Liu G, Lin J, Zhang D, Lin D
Animals : an open access journal from MDPI 2020 Dec 27;11(1)
Animals : an open access journal from MDPI 2020 Dec 27;11(1)
Discovery and Biological Evaluation of CD147 N-Glycan Inhibitors: A New Direction in the Treatment of Tumor Metastasis.
Li W, Wang D, Ge Y, Zhang L, Wu J, Liu D
Molecules (Basel, Switzerland) 2020 Dec 23;26(1)
Molecules (Basel, Switzerland) 2020 Dec 23;26(1)
Radiosensitization Effect of AGuIX, a Gadolinium-Based Nanoparticle, in Nonsmall Cell Lung Cancer.
Du Y, Sun H, Lux F, Xie Y, Du L, Xu C, Zhang H, He N, Wang J, Liu Y, Leduc G, Doussineau T, Ji K, Wang Q, Lin Z, Wang Y, Liu Q, Tillement O
ACS applied materials & interfaces 2020 Dec 23;12(51):56874-56885
ACS applied materials & interfaces 2020 Dec 23;12(51):56874-56885
Lanthanum chloride causes blood-brain barrier disruption through intracellular calcium-mediated RhoA/Rho kinase signaling and myosin light chain kinase.
Wu J, Yang J, Yu M, Sun W, Han Y, Lu X, Jin C, Wu S, Cai Y
Metallomics : integrated biometal science 2020 Dec 23;12(12):2075-2083
Metallomics : integrated biometal science 2020 Dec 23;12(12):2075-2083
Schistosoma mansoni eggs induce Wnt/β-catenin signaling and activate the protooncogene c-Jun in human and hamster colon.
Weglage J, Wolters F, Hehr L, Lichtenberger J, Wulz C, Hempel F, Baier A, Quack T, Köhler K, Longerich T, Schramm G, Irungbam K, Mueller H, von Buelow V, Tschuschner A, Odenthal M, Drebber U, Arousy ME, Ramalho LNZ, Bankov K, Wild P, Pons-Kühnemann J, Tschammer J, Grevelding CG, Roeb E, Roderfeld M
Scientific reports 2020 Dec 23;10(1):22373
Scientific reports 2020 Dec 23;10(1):22373
CircPlekha7 plays an anti-fibrotic role in intrauterine adhesions by modulating endometrial stromal cell proliferation and apoptosis.
Xie W, He M, Liu Y, Huang X, Song D, Xiao Y
The Journal of reproduction and development 2020 Dec 22;66(6):493-504
The Journal of reproduction and development 2020 Dec 22;66(6):493-504
Rapalink-1 Targets Glioblastoma Stem Cells and Acts Synergistically with Tumor Treating Fields to Reduce Resistance against Temozolomide.
Vargas-Toscano A, Nickel AC, Li G, Kamp MA, Muhammad S, Leprivier G, Fritsche E, Barker RA, Sabel M, Steiger HJ, Zhang W, Hänggi D, Kahlert UD
Cancers 2020 Dec 21;12(12)
Cancers 2020 Dec 21;12(12)
MELK is an oncogenic kinase essential for metastasis, mitotic progression, and programmed death in lung carcinoma.
Tang Q, Li W, Zheng X, Ren L, Liu J, Li S, Wang J, Du G
Signal transduction and targeted therapy 2020 Dec 2;5(1):279
Signal transduction and targeted therapy 2020 Dec 2;5(1):279
LncRNA LINC00998 inhibits the malignant glioma phenotype via the CBX3-mediated c-Met/Akt/mTOR axis.
Cai H, Yu Y, Ni X, Li C, Hu Y, Wang J, Chen F, Xi S, Chen Z
Cell death & disease 2020 Dec 2;11(12):1032
Cell death & disease 2020 Dec 2;11(12):1032
Variants in RABL2A causing male infertility and ciliopathy.
Ding X, Fragoza R, Singh P, Zhang S, Yu H, Schimenti JC
Human molecular genetics 2020 Dec 18;29(20):3402-3411
Human molecular genetics 2020 Dec 18;29(20):3402-3411
Aldehyde dehydrogenase 2 protects against sympathetic excitation-induced cardiac fibrosis.
Yuan Q, Yang F, Dai S, Wang Z, Xu Y, Xu BC, Sun Y, Zheng B, Zhao Y, Wang W, Liu B, Wang J, Cui S, Cao S, Zhang R, Xue L, Wei S, Xue M, Xu T, Xu F, Chen Y
Biochemical and biophysical research communications 2020 Dec 17;533(4):1427-1434
Biochemical and biophysical research communications 2020 Dec 17;533(4):1427-1434
Pharmacological activation of the p53 pathway by a new compound CYZ2017 exerts anti-tumor effects.
Han Y, Ren Z, Wu Y, Chen Y, Cui Z, Zhu T, Ma M, Du Y, Dong S
Biochemical and biophysical research communications 2020 Dec 17;533(4):1069-1075
Biochemical and biophysical research communications 2020 Dec 17;533(4):1069-1075
The deubiquitinase USP36 Regulates DNA replication stress and confers therapeutic resistance through PrimPol stabilization.
Yan Y, Xu Z, Huang J, Guo G, Gao M, Kim W, Zeng X, Kloeber JA, Zhu Q, Zhao F, Luo K, Lou Z
Nucleic acids research 2020 Dec 16;48(22):12711-12726
Nucleic acids research 2020 Dec 16;48(22):12711-12726
S119N Mutation of the E3 Ubiquitin Ligase SPOP Suppresses SLC7A1 Degradation to Regulate Hepatoblastoma Progression.
He W, Zhang J, Liu B, Liu X, Liu G, Xie L, He J, Wei M, Li K, Ma J, Dong R, Ma D, Dong K, Ye M
Molecular therapy oncolytics 2020 Dec 16;19:149-162
Molecular therapy oncolytics 2020 Dec 16;19:149-162
Exosome-mediated Hic-5 regulates proliferation and apoptosis of osteosarcoma via Wnt/β-catenin signal pathway.
Sha L, Ma D, Chen C
Aging 2020 Dec 13;12(23):23598-23608
Aging 2020 Dec 13;12(23):23598-23608
Hugan Qingzhi medication ameliorates free fatty acid-induced L02 hepatocyte endoplasmic reticulum stress by regulating the activation of PKC-δ.
Yang M, Chen Z, Xiang S, Xia F, Tang W, Yao X, Zhou B
BMC complementary medicine and therapies 2020 Dec 11;20(1):377
BMC complementary medicine and therapies 2020 Dec 11;20(1):377
Epigenetic Inactivation of α-Internexin Accelerates Microtubule Polymerization in Colorectal Cancer.
Li Y, Bai L, Yu H, Cai D, Wang X, Huang B, Peng S, Huang M, Cao G, Kaz AM, Grady WM, Wang J, Luo Y
Cancer research 2020 Dec 1;80(23):5203-5215
Cancer research 2020 Dec 1;80(23):5203-5215
Microtubule poleward flux in human cells is driven by the coordinated action of four kinesins.
Steblyanko Y, Rajendraprasad G, Osswald M, Eibes S, Jacome A, Geley S, Pereira AJ, Maiato H, Barisic M
The EMBO journal 2020 Dec 1;39(23):e105432
The EMBO journal 2020 Dec 1;39(23):e105432
FGF signaling regulates development by processes beyond canonical pathways.
Ray AT, Mazot P, Brewer JR, Catela C, Dinsmore CJ, Soriano P
Genes & development 2020 Dec 1;34(23-24):1735-1752
Genes & development 2020 Dec 1;34(23-24):1735-1752
Silencing of the lncRNA TUG1 attenuates the epithelial-mesenchymal transition of renal tubular epithelial cells by sponging miR-141-3p via regulating β-catenin.
Zhang B, Zhao C, Hou L, Wu Y
American journal of physiology. Renal physiology 2020 Dec 1;319(6):F1125-F1134
American journal of physiology. Renal physiology 2020 Dec 1;319(6):F1125-F1134
iTRAQ-based proteomics implies inflammasome pathway activation in the prefrontal cortex of CSDS mice may influence resilience and susceptibility.
Lan T, Bai M, Chen X, Wang Y, Li Y, Tian Y, He Y, Wu Z, Yu H, Chen Z, Chen C, Yu Y, Cheng K, Xie P
Life sciences 2020 Dec 1;262:118501
Life sciences 2020 Dec 1;262:118501
LncRNA Gm16410 regulates PM(2.5)-induced lung Endothelial-Mesenchymal Transition via the TGF-β1/Smad3/p-Smad3 pathway.
Ma K, Li C, Xu J, Ren F, Xu X, Liu C, Niu B, Li F
Ecotoxicology and environmental safety 2020 Dec 1;205:111327
Ecotoxicology and environmental safety 2020 Dec 1;205:111327
Inhibition of autophagy enhances cadmium-induced apoptosis in duck renal tubular epithelial cells.
Wang C, Nie G, Zhuang Y, Hu R, Wu H, Xing C, Li G, Hu G, Yang F, Zhang C
Ecotoxicology and environmental safety 2020 Dec 1;205:111188
Ecotoxicology and environmental safety 2020 Dec 1;205:111188
Cadmium inhibits apoptosis of human esophageal epithelial cells by upregulating CDK6.
Yang J, Guo T, Liang X, Zhai Y, Cheng Y, Sun H, Cui Y, Cheng X
Ecotoxicology and environmental safety 2020 Dec 1;205:111146
Ecotoxicology and environmental safety 2020 Dec 1;205:111146
E3 ligase FBXW7 restricts M2-like tumor-associated macrophage polarization by targeting c-Myc.
Zhong L, Zhang Y, Li M, Song Y, Liu D, Yang X, Yang D, Qu H, Lai L, Wang Q, Chen Z
Aging 2020 Dec 1;12(23):24394-24423
Aging 2020 Dec 1;12(23):24394-24423
Cigarette smoke extract induces airway epithelial cell death via repressing PRMT6/AKT signaling.
Li T, Fanning KV, Nyunoya T, Chen Y, Zou C
Aging 2020 Dec 1;12(23):24301-24317
Aging 2020 Dec 1;12(23):24301-24317
Stachydrine ameliorates the progression of intervertebral disc degeneration via the PI3K/Akt/NF-κB signaling pathway: in vitro and in vivo studies.
Shao Z, Lu J, Zhang C, Zeng G, Chen B, Liang H, Wu A, Zhang X, Wang X
Food & function 2020 Dec 1;11(12):10864-10875
Food & function 2020 Dec 1;11(12):10864-10875
The induction and characterization of monoclonal antibodies specific to GP of Ebola virus.
Tian X, Chen D, Wang H, Xu S, Zhu L, Wu X, Wu Z
Journal of medical virology 2020 Aug;92(8):996-1006
Journal of medical virology 2020 Aug;92(8):996-1006
The vulnerability of motor and frontal cortex-dependent behaviors in mice expressing ALS-linked mutation in TDP-43.
Wong P, Ho WY, Yen YC, Sanford E, Ling SC
Neurobiology of aging 2020 Aug;92:43-60
Neurobiology of aging 2020 Aug;92:43-60
Differential Effects of Components in Artemisia annua Extract on the Induction of Drug-Metabolizing Enzyme Expression Mediated by Nuclear Receptors.
Zhang X, Meng R, Wang H, Xing J
Planta medica 2020 Aug;86(12):867-875
Planta medica 2020 Aug;86(12):867-875
Rhein attenuates renal inflammatory injury of uric acid nephropathy via lincRNA-Cox2/miR-150-5p/STAT1 axis.
Hu J, Yang Z, Wu H, Wang D
International immunopharmacology 2020 Aug;85:106620
International immunopharmacology 2020 Aug;85:106620
Melatonin alleviates intestinal injury, neuroinflammation and cognitive dysfunction caused by intestinal ischemia/reperfusion.
Yang B, Zhang LY, Chen Y, Bai YP, Jia J, Feng JG, Liu KX, Zhou J
International immunopharmacology 2020 Aug;85:106596
International immunopharmacology 2020 Aug;85:106596
IL-38 alleviates the inflammatory response and the degeneration of nucleus pulposus cells via inhibition of the NF-κB signaling pathway in vitro.
Yu H, Liu Y, Xie W, Xie Q, Liu Q, Cheng L
International immunopharmacology 2020 Aug;85:106592
International immunopharmacology 2020 Aug;85:106592
Knockdown of interferon-induced transmembrane protein 1 inhibited proliferation, induced cell cycle arrest and apoptosis, and suppressed MAPK signaling pathway in pancreatic cancer cells.
Zhang L, Wang Z, Kong D, Zhao X, Chen X, Chai W
Bioscience, biotechnology, and biochemistry 2020 Aug;84(8):1603-1613
Bioscience, biotechnology, and biochemistry 2020 Aug;84(8):1603-1613
To what extent should the intestinal be resected proximally after radiotherapy: hint from a pathological view.
Wu PH, Zhong QH, Ma TH, Qin QY, Huang XY, Kuang YY, Wang HM, Yuan ZX, Wang L, Chen DC
Gastroenterology report 2020 Aug;8(4):277-285
Gastroenterology report 2020 Aug;8(4):277-285
Rationalized inhibition of mixed lineage kinase 3 and CD70 enhances life span and antitumor efficacy of CD8(+) T cells.
Kumar S, Singh SK, Viswakarma N, Sondarva G, Nair RS, Sethupathi P, Dorman M, Sinha SC, Hoskins K, Thatcher G, Rana B, Rana A
Journal for immunotherapy of cancer 2020 Aug;8(2)
Journal for immunotherapy of cancer 2020 Aug;8(2)
The role of miR-34c-5p/Notch in epithelial-mesenchymal transition (EMT) in endometriosis.
Luo Y, Wang D, Chen S, Yang Q
Cellular signalling 2020 Aug;72:109666
Cellular signalling 2020 Aug;72:109666
miR-296-5p suppresses stem cell potency of hepatocellular carcinoma cells via regulating Brg1/Sall4 axis.
Shi DM, Shi XL, Xing KL, Zhou HX, Lu LL, Wu WZ
Cellular signalling 2020 Aug;72:109650
Cellular signalling 2020 Aug;72:109650
m(6)A mRNA Methylation Controls Functional Maturation in Neonatal Murine β-Cells.
Wang Y, Sun J, Lin Z, Zhang W, Wang S, Wang W, Wang Q, Ning G
Diabetes 2020 Aug;69(8):1708-1722
Diabetes 2020 Aug;69(8):1708-1722
Metabolomic profiling reveals similar cytotoxic effects and protective functions of quercetin during deoxynivalenol- and 15-acetyl deoxynivalenol-induced cell apoptosis.
Yang YX, Yu S, Jia BX, Liu N, Wu A
Toxicology in vitro : an international journal published in association with BIBRA 2020 Aug;66:104838
Toxicology in vitro : an international journal published in association with BIBRA 2020 Aug;66:104838
miR-410-5p promotes the development of diabetic cardiomyopathy by suppressing PIM1-induced anti-apoptosis.
Xia X, Liang Y, Zheng W, Lin D, Sun S
Molecular and cellular probes 2020 Aug;52:101558
Molecular and cellular probes 2020 Aug;52:101558
Exosomes derived from human exfoliated deciduous teeth ameliorate adult bone loss in mice through promoting osteogenesis.
Wei J, Song Y, Du Z, Yu F, Zhang Y, Jiang N, Ge X
Journal of molecular histology 2020 Aug;51(4):455-466
Journal of molecular histology 2020 Aug;51(4):455-466
The AKR1B1 inhibitor epalrestat suppresses the progression of cervical cancer.
Ji J, Xu MX, Qian TY, Zhu SZ, Jiang F, Liu ZX, Xu WS, Zhou J, Xiao MB
Molecular biology reports 2020 Aug;47(8):6091-6103
Molecular biology reports 2020 Aug;47(8):6091-6103
Neferine Inhibits Expression of Inflammatory Mediators and Matrix Degrading Enzymes in IL-1β-Treated Rat Chondrocytes via Suppressing MAPK and NF-κB Signaling Pathways.
Ni B, Huang X, Xi Y, Mao Z, Chu X, Zhang R, Ma X, You H
Inflammation 2020 Aug;43(4):1209-1221
Inflammation 2020 Aug;43(4):1209-1221
Schisandrin B improves cerebral ischemia and reduces reperfusion injury in rats through TLR4/NF-κB signaling pathway inhibition.
Fan X, Elkin K, Shi Y, Zhang Z, Cheng Y, Gu J, Liang J, Wang C, Ji X
Neurological research 2020 Aug;42(8):693-702
Neurological research 2020 Aug;42(8):693-702
Rare mutations in the autophagy-regulating gene AMBRA1 contribute to human neural tube defects.
Ye J, Tong Y, Lv J, Peng R, Chen S, Kuang L, Su K, Zheng Y, Zhang T, Zhang F, Jin L, Yang X, Wang H
Human mutation 2020 Aug;41(8):1383-1393
Human mutation 2020 Aug;41(8):1383-1393
Red nucleus IL-6 mediates the maintenance of neuropathic pain by inducing the productions of TNF-α and IL-1β through the JAK2/STAT3 and ERK signaling pathways.
Yang QQ, Li HN, Zhang ST, Yu YL, Wei W, Zhang X, Wang JY, Zeng XY
Neuropathology : official journal of the Japanese Society of Neuropathology 2020 Aug;40(4):347-357
Neuropathology : official journal of the Japanese Society of Neuropathology 2020 Aug;40(4):347-357
Astragaloside IV attenuates chronic intermittent hypoxia-induced myocardial injury by modulating Ca(2+) homeostasis.
Jiang S, Jiao G, Chen Y, Han M, Wang X, Liu W
Cell biochemistry and function 2020 Aug;38(6):710-720
Cell biochemistry and function 2020 Aug;38(6):710-720
MiR-129-5p alleviates myocardial injury by targeting suppressor of cytokine signaling 2 after ischemia/reperfusion.
Ma R, Chen X, Ma Y, Bai G, Li DS
The Kaohsiung journal of medical sciences 2020 Aug;36(8):599-606
The Kaohsiung journal of medical sciences 2020 Aug;36(8):599-606
Effect of AmyTrap, an amyloid-β binding drug, on Aβ induced mitochondrial dysfunction and tau phosphorylation in cultured neuroblastoma cells.
Gandbhir O, Sundaram P
Metabolic brain disease 2020 Aug;35(6):923-931
Metabolic brain disease 2020 Aug;35(6):923-931
Curcumin inhibits calcification of human aortic valve interstitial cells by interfering NF-κB, AKT, and ERK pathways.
Zhou T, Wang Y, Liu M, Huang Y, Shi J, Dong N, Xu K
Phytotherapy research : PTR 2020 Aug;34(8):2074-2081
Phytotherapy research : PTR 2020 Aug;34(8):2074-2081
Src-mediated phosphorylation of GAPDH regulates its nuclear localization and cellular response to DNA damage.
Ci S, Xia W, Liang W, Qin L, Zhang Y, Dianov GL, Wang M, Zhao X, Wu C, Alagamuthu KK, Hu Z, He L, Pan F, Guo Z
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Aug;34(8):10443-10461
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Aug;34(8):10443-10461
Hydrogen sulphide ameliorating skeletal muscle atrophy in db/db mice via Muscle RING finger 1 S-sulfhydration.
Lu F, Lu B, Zhang L, Wen J, Wang M, Zhang S, Li Q, Shu F, Sun Y, Liu N, Peng S, Zhao Y, Dong S, Zhao D, Lu F, Zhang W
Journal of cellular and molecular medicine 2020 Aug;24(16):9362-9377
Journal of cellular and molecular medicine 2020 Aug;24(16):9362-9377
Effects of PYRIN-containing Apaf1-like protein 1 on isoflurane-induced postoperative cognitive dysfunction in aged rats.
Zhang X, Fan X, Li F, Qiu J, Zhang Y
Molecular medicine reports 2020 Aug;22(2):1391-1399
Molecular medicine reports 2020 Aug;22(2):1391-1399
Overexpression of negative regulator of ubiquitin-like proteins 1 (NUB1) inhibits proliferation and invasion of gastric cancer cells through upregulation of p27Kip1 and inhibition of epithelial-mesenchymal transition.
Zhang D, Wu P, Zhang Z, An W, Zhang C, Pan S, Tan Y, Xu H
Pathology, research and practice 2020 Aug;216(8):153002
Pathology, research and practice 2020 Aug;216(8):153002
Cloning of the XPD gene and its function in malignant melanoma cells.
Wang Y, Zhou Y, Wang Y, Peng C, Gao M
Oncology letters 2020 Aug;20(2):1803-1809
Oncology letters 2020 Aug;20(2):1803-1809
miR-140-3p enhances cisplatin sensitivity and attenuates stem cell-like properties through repressing Wnt/β-catenin signaling in lung adenocarcinoma cells.
Wu S, Wang H, Pan Y, Yang X, Wu D
Experimental and therapeutic medicine 2020 Aug;20(2):1664-1674
Experimental and therapeutic medicine 2020 Aug;20(2):1664-1674
ZMIZ1 promotes the proliferation and migration of melanocytes in vitiligo.
Li M, Fan Y, Wang Y, Xu J, Xu H
Experimental and therapeutic medicine 2020 Aug;20(2):1371-1378
Experimental and therapeutic medicine 2020 Aug;20(2):1371-1378
BX795 demonstrates potent antiviral benefits against herpes simplex Virus-1 infection of human cell lines.
Iqbal A, Suryawanshi R, Yadavalli T, Volety I, Shukla D
Antiviral research 2020 Aug;180:104814
Antiviral research 2020 Aug;180:104814
miR-106a Regulates Cell Proliferation and Autophagy by Targeting LKB1 in HPV-16-Associated Cervical Cancer.
Cui X, Wang X, Zhou X, Jia J, Chen H, Zhao W
Molecular cancer research : MCR 2020 Aug;18(8):1129-1141
Molecular cancer research : MCR 2020 Aug;18(8):1129-1141
Targeting G6PD reverses paclitaxel resistance in ovarian cancer by suppressing GSTP1.
Feng Q, Li X, Sun W, Sun M, Li Z, Sheng H, Xie F, Zhang S, Shan C
Biochemical pharmacology 2020 Aug;178:114092
Biochemical pharmacology 2020 Aug;178:114092
Celastrol ameliorates autoimmune disorders in Trex1-deficient mice.
Liu Y, Xiao N, Du H, Kou M, Lin L, Huang M, Zhang S, Xu S, Li D, Chen Q
Biochemical pharmacology 2020 Aug;178:114090
Biochemical pharmacology 2020 Aug;178:114090
Hippocampal glutamatergic synapses impairment mediated novel-object recognition dysfunction in rats with neuropathic pain.
Xiong B, Zhang W, Zhang L, Huang X, Zhou W, Zou Q, Manyande A, Wang J, Tian Y, Tian X
Pain 2020 Aug;161(8):1824-1836
Pain 2020 Aug;161(8):1824-1836
Correcting abnormalities in miR-124/PTPN1 signaling rescues tau pathology in Alzheimer's disease.
Hou TY, Zhou Y, Zhu LS, Wang X, Pang P, Wang DQ, Liuyang ZY, Man H, Lu Y, Zhu LQ, Liu D
Journal of neurochemistry 2020 Aug;154(4):441-457
Journal of neurochemistry 2020 Aug;154(4):441-457
Overexpression of PTEN regulated by miR-19b and miR-494 in the villous of recurrent spontaneous abortion patients.
Tian S, Yu J, Zhang Y, Bian Y, Ma J, Yan J
Journal of reproductive immunology 2020 Aug;140:103133
Journal of reproductive immunology 2020 Aug;140:103133
Apocynum venetum leaf extract protects against H(2)O(2)-induced oxidative stress by increasing autophagy in PC12 cells.
Feng Y, Jiang C, Yang F, Chen Z, Li Z
Biomedical reports 2020 Aug;13(2):6
Biomedical reports 2020 Aug;13(2):6
Prunella vulgaris L. attenuates experimental autoimmune thyroiditis by inducing indoleamine 2,3-dioxygenase 1 expression and regulatory T cell expansion.
Qiu H, Zhang J, Guo Q, Zhang Y, Zhong X
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Aug;128:110288
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Aug;128:110288
LINC00467 promotes cell proliferation and stemness in lung adenocarcinoma by sponging miR-4779 and miR-7978.
Chang Y, Yang L
Journal of cellular biochemistry 2020 Aug;121(8-9):3691-3699
Journal of cellular biochemistry 2020 Aug;121(8-9):3691-3699
Glibenclamide restores dopaminergic reward circuitry in obese mice through interscauplar brown adipose tissue.
Kuo YY, Lin JK, Lin YT, Chen JC, Kuo YM, Chen PS, Wu SN, Chen PC
Psychoneuroendocrinology 2020 Aug;118:104712
Psychoneuroendocrinology 2020 Aug;118:104712
MiR-195 suppression alleviates apoptosis and oxidative stress in CCl4-induced ALI in mice by targeting Pim-1.
Yang K, Zou Z, Wu Y, Hu G
Experimental and molecular pathology 2020 Aug;115:104438
Experimental and molecular pathology 2020 Aug;115:104438
Sarcopenia is attenuated by TRB3 knockout in aging mice via the alleviation of atrophy and fibrosis of skeletal muscles.
Shang GK, Han L, Wang ZH, Liu YP, Yan SB, Sai WW, Wang D, Li YH, Zhang W, Zhong M
Journal of cachexia, sarcopenia and muscle 2020 Aug;11(4):1104-1120
Journal of cachexia, sarcopenia and muscle 2020 Aug;11(4):1104-1120
The mechanism of Chinese herbal formula HQT in the treatment of rheumatoid arthritis is related to its regulation of lncRNA uc.477 and miR-19b.
Wang M, Mei L, Liu Z, Tang X, Wu X, Chen X, Zhao Y, Huang Q, Huang R
Journal of leukocyte biology 2020 Aug;108(2):519-529
Journal of leukocyte biology 2020 Aug;108(2):519-529
MiR-221/222 promote migration and invasion, and inhibit autophagy and apoptosis by modulating ATG10 in aggressive papillary thyroid carcinoma.
Shen H, Lin Z, Shi H, Wu L, Ma B, Li H, Yin B, Tang J, Yu H, Yin X
3 Biotech 2020 Aug;10(8):339
3 Biotech 2020 Aug;10(8):339
METTL3 and N6-Methyladenosine Promote Homologous Recombination-Mediated Repair of DSBs by Modulating DNA-RNA Hybrid Accumulation.
Zhang C, Chen L, Peng D, Jiang A, He Y, Zeng Y, Xie C, Zhou H, Luo X, Liu H, Chen L, Ren J, Wang W, Zhao Y
Molecular cell 2020 Aug 6;79(3):425-442.e7
Molecular cell 2020 Aug 6;79(3):425-442.e7
Partial MHC/neuroantigen peptide constructs attenuate methamphetamine-seeking and brain chemokine (C-C motif) ligand 2 levels in rats.
Loftis JM, Navis T, Taylor J, Hudson R, Person U, Lattal KM, Vandenbark AA, Shirley R, Huckans M
European journal of pharmacology 2020 Aug 5;880:173175
European journal of pharmacology 2020 Aug 5;880:173175
Schisandrin ameliorates cognitive deficits, endoplasmic reticulum stress and neuroinflammation in streptozotocin (STZ)-induced Alzheimer's disease rats.
Song L, Piao Z, Yao L, Zhang L, Lu Y
Experimental animals 2020 Aug 5;69(3):363-373
Experimental animals 2020 Aug 5;69(3):363-373
Butyrate-mediated autophagy inhibition limits cytosolic Salmonella Infantis replication in the colon of pigs treated with a mixture of Lactobacillus and Bacillus.
Chu B, Zhu Y, Su J, Xia B, Zou Y, Nie J, Zhang W, Wang J
Veterinary research 2020 Aug 5;51(1):99
Veterinary research 2020 Aug 5;51(1):99
Neutrophil extracellular traps amplify neutrophil recruitment and inflammation in neutrophilic asthma by stimulating the airway epithelial cells to activate the TLR4/ NF-κB pathway and secrete chemokines.
Wan R, Jiang J, Hu C, Chen X, Chen C, Zhao B, Hu X, Zheng Z, Li Y
Aging 2020 Aug 5;12(17):16820-16836
Aging 2020 Aug 5;12(17):16820-16836
Icotinib Attenuates Monocrotaline-Induced Pulmonary Hypertension by Preventing Pulmonary Arterial Smooth Muscle Cell Dysfunction.
Peng LY, Yu M, Yang MX, Liu P, Zhou H, Huang W, Kong H, Xie WP
American journal of hypertension 2020 Aug 4;33(8):775-783
American journal of hypertension 2020 Aug 4;33(8):775-783
Macrophage K63-Linked Ubiquitination of YAP Promotes Its Nuclear Localization and Exacerbates Atherosclerosis.
Liu M, Yan M, Lv H, Wang B, Lv X, Zhang H, Xiang S, Du J, Liu T, Tian Y, Zhang X, Zhou F, Cheng T, Zhu Y, Jiang H, Cao Y, Ai D
Cell reports 2020 Aug 4;32(5):107990
Cell reports 2020 Aug 4;32(5):107990
Nicotinamide Mononucleotide Supplementation Reverses the Declining Quality of Maternally Aged Oocytes.
Miao Y, Cui Z, Gao Q, Rui R, Xiong B
Cell reports 2020 Aug 4;32(5):107987
Cell reports 2020 Aug 4;32(5):107987
miR-4634 augments the anti-tumor effects of RAD001 and associates well with clinical prognosis of non-small cell lung cancer.
Liu S, Zang H, Zheng H, Wang W, Wen Q, Zhan Y, Yang Y, Ning Y, Wang H, Fan S
Scientific reports 2020 Aug 4;10(1):13079
Scientific reports 2020 Aug 4;10(1):13079
An Optimized Reverse Genetics System Suitable for Efficient Recovery of Simian, Human, and Murine-Like Rotaviruses.
Sánchez-Tacuba L, Feng N, Meade NJ, Mellits KH, Jaïs PH, Yasukawa LL, Resch TK, Jiang B, López S, Ding S, Greenberg HB
Journal of virology 2020 Aug 31;94(18)
Journal of virology 2020 Aug 31;94(18)
[Down-regulation of pannexin 2 channel enhances cisplatin-induced apoptosis in testicular cancer I-10 cells].
Yao Y, Dong S, Zhu C, Hu M, Du B, Tong X
Nan fang yi ke da xue xue bao = Journal of Southern Medical University 2020 Aug 30;40(8):1090-1096
Nan fang yi ke da xue xue bao = Journal of Southern Medical University 2020 Aug 30;40(8):1090-1096
16-Hydroxycleroda-3,13-dien-15,16-olide Induces Apoptosis in Human Bladder Cancer Cells through Cell Cycle Arrest, Mitochondria ROS Overproduction, and Inactivation of EGFR-Related Signalling Pathways.
Chen YC, Wang PY, Huang BM, Chen YJ, Lee WC, Chen YC
Molecules (Basel, Switzerland) 2020 Aug 30;25(17)
Molecules (Basel, Switzerland) 2020 Aug 30;25(17)
Promising xenograft animal model recapitulating the features of human pancreatic cancer.
Miao JX, Wang JY, Li HZ, Guo HR, Dunmall LSC, Zhang ZX, Cheng ZG, Gao DL, Dong JZ, Wang ZD, Wang YH
World journal of gastroenterology 2020 Aug 28;26(32):4802-4816
World journal of gastroenterology 2020 Aug 28;26(32):4802-4816
Glutamyl-Prolyl-tRNA Synthetase Regulates Proline-Rich Pro-Fibrotic Protein Synthesis During Cardiac Fibrosis.
Wu J, Subbaiah KCV, Xie LH, Jiang F, Khor ES, Mickelsen D, Myers JR, Tang WHW, Yao P
Circulation research 2020 Aug 28;127(6):827-846
Circulation research 2020 Aug 28;127(6):827-846
The HMGB1-2 Ovarian Cancer Interactome. The Role of HMGB Proteins and Their Interacting Partners MIEN1 and NOP53 in Ovary Cancer and Drug-Response.
Cámara-Quílez M, Barreiro-Alonso A, Vizoso-Vázquez Á, Rodríguez-Belmonte E, Quindós-Varela M, Lamas-Maceiras M, Cerdán ME
Cancers 2020 Aug 27;12(9)
Cancers 2020 Aug 27;12(9)
Chidamide, a histone deacetylase inhibitor, inhibits autophagy and exhibits therapeutic implication in chronic lymphocytic leukemia.
Kong YL, Pan BH, Liang JH, Zhu HY, Wang L, Xia Y, Wu JZ, Fan L, Li JY, Xu W
Aging 2020 Aug 27;12(16):16083-16098
Aging 2020 Aug 27;12(16):16083-16098
The Circadian Hormone Melatonin Inhibits Morphine-Induced Tolerance and Inflammation via the Activation of Antioxidative Enzymes.
Chen IJ, Yang CP, Lin SH, Lai CM, Wong CS
Antioxidants (Basel, Switzerland) 2020 Aug 22;9(9)
Antioxidants (Basel, Switzerland) 2020 Aug 22;9(9)
Small molecules targeting RORγt inhibit autoimmune disease by suppressing Th17 cell differentiation.
Tan J, Liu H, Huang M, Li N, Tang S, Meng J, Tang S, Zhou H, Kijlstra A, Yang P, Hou S
Cell death & disease 2020 Aug 22;11(8):697
Cell death & disease 2020 Aug 22;11(8):697
The gut microbiota regulates autism-like behavior by mediating vitamin B(6) homeostasis in EphB6-deficient mice.
Li Y, Luo ZY, Hu YY, Bi YW, Yang JM, Zou WJ, Song YL, Li S, Shen T, Li SJ, Huang L, Zhou AJ, Gao TM, Li JM
Microbiome 2020 Aug 20;8(1):120
Microbiome 2020 Aug 20;8(1):120
In Vitro and In Vivo Activity, Tolerability, and Mechanism of Action of BX795 as an Antiviral against Herpes Simplex Virus 2 Genital Infection.
Hopkins J, Yadavalli T, Suryawanshi R, Qatanani F, Volety I, Koganti R, Iqbal A, Shukla D
Antimicrobial agents and chemotherapy 2020 Aug 20;64(9)
Antimicrobial agents and chemotherapy 2020 Aug 20;64(9)
A kinase-independent function for AURORA-A in replisome assembly during DNA replication initiation.
Guarino Almeida E, Renaudin X, Venkitaraman AR
Nucleic acids research 2020 Aug 20;48(14):7844-7855
Nucleic acids research 2020 Aug 20;48(14):7844-7855
A CRISPR knockout negative screen reveals synergy between CDKs inhibitor and metformin in the treatment of human cancer in vitro and in vivo.
Ma Y, Zhu Q, Liang J, Li Y, Li M, Zhang Y, Wang X, Zeng Y, Jiao Y
Signal transduction and targeted therapy 2020 Aug 19;5(1):152
Signal transduction and targeted therapy 2020 Aug 19;5(1):152
Exosomal Delivery of AntagomiRs Targeting Viral and Cellular MicroRNAs Synergistically Inhibits Cancer Angiogenesis.
Wang J, Jiang Q, Faleti OD, Tsang CM, Zhao M, Wu G, Tsao SW, Fu M, Chen Y, Ding T, Chong T, Long Y, Yang X, Zhang Y, Cai Y, Li H, Peng M, Lyu X, Li X
Molecular therapy. Nucleic acids 2020 Aug 19;22:153-165
Molecular therapy. Nucleic acids 2020 Aug 19;22:153-165
Antidepressant-like Effect of Merazin Hydrate Depends on NO/ERK by Suppressing Its Downstream NF-κB or Nonactivating CREB/BDNF in Mouse Hippocampus.
Wu L, Liu X, Huang Y, Lu C, Zhou J, Ren P, Huang X
ACS chemical neuroscience 2020 Aug 19;11(16):2472-2481
ACS chemical neuroscience 2020 Aug 19;11(16):2472-2481
Ubiquitin-Conjugating Enzyme 2S Enhances Viral Replication by Inhibiting Type I IFN Production through Recruiting USP15 to Deubiquitinate TBK1.
Huang L, Liu H, Zhang K, Meng Q, Hu L, Zhang Y, Xiang Z, Li J, Yang Y, Chen Y, Cui S, Tang H, Pei H, Bu Z, Weng C
Cell reports 2020 Aug 18;32(7):108044
Cell reports 2020 Aug 18;32(7):108044
Novel dot-blot assay for detection of vascular Notch3 aggregates in patients with CADASIL.
Ma Y, Ueda M, Ueda A, Shinriki S, Nagatoshi A, Isoguchi A, Okada M, Tasaki M, Nomura T, Inoue Y, Masuda T, Misumi Y, Yamashita T, Matsui H, Ando Y
Journal of the neurological sciences 2020 Aug 15;415:116931
Journal of the neurological sciences 2020 Aug 15;415:116931
Lamin B2 promotes the malignant phenotype of non-small cell lung cancer cells by upregulating dimethylation of histone 3 lysine 9.
Zhang MY, Han YC, Han Q, Liang Y, Luo Y, Wei L, Yan T, Yang Y, Liu SL, Wang EH
Experimental cell research 2020 Aug 15;393(2):112090
Experimental cell research 2020 Aug 15;393(2):112090
Lactobacillus johnsonii L531 Ameliorates Escherichia coli-Induced Cell Damage via Inhibiting NLRP3 Inflammasome Activity and Promoting ATG5/ATG16L1-Mediated Autophagy in Porcine Mammary Epithelial Cells.
Zou YJ, Xu JJ, Wang X, Zhu YH, Wu Q, Wang JF
Veterinary sciences 2020 Aug 14;7(3)
Veterinary sciences 2020 Aug 14;7(3)
Magnetic targeting enhances the cutaneous wound healing effects of human mesenchymal stem cell-derived iron oxide exosomes.
Li X, Wang Y, Shi L, Li B, Li J, Wei Z, Lv H, Wu L, Zhang H, Yang B, Xu X, Jiang J
Journal of nanobiotechnology 2020 Aug 14;18(1):113
Journal of nanobiotechnology 2020 Aug 14;18(1):113
TRIM59 attenuates IL-1β-driven cartilage matrix degradation in osteoarthritis via direct suppression of NF-κB and JAK2/STAT3 signaling pathway.
Teng Y, Ni G, Zhang W, Hua J, Sun L, Zheng M, Dong Q, Huang W
Biochemical and biophysical research communications 2020 Aug 13;529(1):28-34
Biochemical and biophysical research communications 2020 Aug 13;529(1):28-34
A cell-based high-throughput screen identifies drugs that cause bleeding disorders by off-targeting the vitamin K cycle.
Chen X, Li C, Jin DY, Ingram B, Hao Z, Bai X, Stafford DW, Hu K, Tie JK
Blood 2020 Aug 13;136(7):898-908
Blood 2020 Aug 13;136(7):898-908
Flavagline synthetic derivative induces senescence in glioblastoma cancer cells without being toxic to healthy astrocytes.
Harmouch E, Seitlinger J, Chaddad H, Ubeaud-Sequier G, Barths J, Saidu S, Désaubry L, Grandemange S, Massfelder T, Fuhrmann G, Fioretti F, Dontenwill M, Benkirane-Jessel N, Idoux-Gillet Y
Scientific reports 2020 Aug 13;10(1):13750
Scientific reports 2020 Aug 13;10(1):13750
Acetylation of Cytidine Residues Boosts HIV-1 Gene Expression by Increasing Viral RNA Stability.
Tsai K, Jaguva Vasudevan AA, Martinez Campos C, Emery A, Swanstrom R, Cullen BR
Cell host & microbe 2020 Aug 12;28(2):306-312.e6
Cell host & microbe 2020 Aug 12;28(2):306-312.e6
Amyloid precursor protein glycosylation is altered in the brain of patients with Alzheimer's disease.
Boix CP, Lopez-Font I, Cuchillo-Ibañez I, Sáez-Valero J
Alzheimer's research & therapy 2020 Aug 12;12(1):96
Alzheimer's research & therapy 2020 Aug 12;12(1):96
Expressional Localization and Functionally Identifying an RNA Editing Enzyme BmADARa of the Silkworm Bombyx mori.
Ye C, Jiang S, Gong M, Min Q, Fan M, Gao J, Meng Y
Insects 2020 Aug 12;11(8)
Insects 2020 Aug 12;11(8)
Qingda granule inhibits angiotensin Ⅱ induced VSMCs proliferation through MAPK and PI3K/AKT pathways.
Yu N, Shen A, Chu J, Huang Y, Zhang L, Lin S, Cai Q, Sankararaman S, Sferra TJ, Chen Y, Peng J
Journal of ethnopharmacology 2020 Aug 10;258:112767
Journal of ethnopharmacology 2020 Aug 10;258:112767
Frequent and mild scrotal heat stress in mice epigenetically alters glucose metabolism in the male offspring.
Wan X, He X, Liu Q, Wang X, Ding X, Li H
American journal of physiology. Endocrinology and metabolism 2020 Aug 1;319(2):E291-E304
American journal of physiology. Endocrinology and metabolism 2020 Aug 1;319(2):E291-E304
Dual-specificity phosphatase 29 is induced during neurogenic skeletal muscle atrophy and attenuates glucocorticoid receptor activity in muscle cell culture.
Cooper LM, West RC, Hayes CS, Waddell DS
American journal of physiology. Cell physiology 2020 Aug 1;319(2):C441-C454
American journal of physiology. Cell physiology 2020 Aug 1;319(2):C441-C454
Chlorogenic acid attenuates cyclophosphamide-induced rat interstitial cystitis.
Luo J, Yang C, Luo X, Yang Y, Li J, Song B, Zhao J, Li L
Life sciences 2020 Aug 1;254:117590
Life sciences 2020 Aug 1;254:117590
Syndecan-1 regulates extracellular matrix expression in keloid fibroblasts via TGF-β1/Smad and MAPK signaling pathways.
Cui J, Jin S, Jin C, Jin Z
Life sciences 2020 Aug 1;254:117326
Life sciences 2020 Aug 1;254:117326
Dandelion Extract Alleviated Lipopolysaccharide-Induced Oxidative Stress through the Nrf2 Pathway in Bovine Mammary Epithelial Cells.
Sun Y, Wu Y, Wang Z, Chen J, Yang Y, Dong G
Toxins 2020 Aug 1;12(8)
Toxins 2020 Aug 1;12(8)
MicroRNA-378-3p/5p suppresses the migration and invasiveness of oral squamous carcinoma cells by inhibiting KLK4 expression.
Cui Z, Sun S, Liu Q, Zhou X, Gao S, Peng P, Li Q
Biochemistry and cell biology = Biochimie et biologie cellulaire 2020 Apr;98(2):154-163
Biochemistry and cell biology = Biochimie et biologie cellulaire 2020 Apr;98(2):154-163
Anethole compromises human sperm function by affecting the sperm intracellular calcium concentration and tyrosine phosphorylation.
Luo T, Wang F, Weng S, Chen H, Kang H, Wang J, Luo S
Reproductive toxicology (Elmsford, N.Y.) 2020 Apr;93:99-105
Reproductive toxicology (Elmsford, N.Y.) 2020 Apr;93:99-105
miR-455-3p enhances chondrocytes apoptosis and inflammation by targeting COL2A1 in the in vitro osteoarthritis model.
Cheng F, Hu H, Sun K, Yan F, Geng Y
Bioscience, biotechnology, and biochemistry 2020 Apr;84(4):695-702
Bioscience, biotechnology, and biochemistry 2020 Apr;84(4):695-702
Glaucocalyxin A alleviates LPS-mediated septic shock and inflammation via inhibiting NLRP3 inflammasome activation.
Hou X, Xu G, Wang Z, Zhan X, Li H, Li R, Shi W, Wang C, Chen Y, Ai Y, Xiao X, Bai Z
International immunopharmacology 2020 Apr;81:106271
International immunopharmacology 2020 Apr;81:106271
Baicalin attenuates hepatic injury in non-alcoholic steatohepatitis cell model by suppressing inflammasome-dependent GSDMD-mediated cell pyroptosis.
Shi H, Zhang Y, Xing J, Liu L, Qiao F, Li J, Chen Y
International immunopharmacology 2020 Apr;81:106195
International immunopharmacology 2020 Apr;81:106195
Cellular secretion and cytotoxicity of transthyretin mutant proteins underlie late-onset amyloidosis and neurodegeneration.
Ibrahim RB, Yeh SY, Lin KP, Ricardo F, Yu TY, Chan CC, Tsai JW, Liu YT
Cellular and molecular life sciences : CMLS 2020 Apr;77(7):1421-1434
Cellular and molecular life sciences : CMLS 2020 Apr;77(7):1421-1434
Synergistic effects of tanshinone IIA and andrographolide on the apoptosis of cancer cells via crosstalk between p53 and reactive oxygen species pathways.
Li Y, Jiang B, Wang R, Wang J, Li Y, Bao Y
Pharmacological reports : PR 2020 Apr;72(2):400-417
Pharmacological reports : PR 2020 Apr;72(2):400-417
Streptococcus pneumoniae aminopeptidase N contributes to bacterial virulence and elicits a strong innate immune response through MAPK and PI3K/AKT signaling.
Wang L, Zhang X, Wu G, Qi Y, Zhang J, Yang J, Wang H, Xu W
Journal of microbiology (Seoul, Korea) 2020 Apr;58(4):330-339
Journal of microbiology (Seoul, Korea) 2020 Apr;58(4):330-339
E6‑regulated overproduction of prostaglandin E2 may inhibit migration of dendritic cells in human papillomavirus 16‑positive cervical lesions.
Huang J, Diao G, Zhang Q, Chen Y, Han J, Guo J
International journal of oncology 2020 Apr;56(4):921-931
International journal of oncology 2020 Apr;56(4):921-931
Effects of rutin on the oxidative stress, proliferation and osteogenic differentiation of periodontal ligament stem cells in LPS-induced inflammatory environment and the underlying mechanism.
Zhao B, Zhang W, Xiong Y, Zhang Y, Zhang D, Xu X
Journal of molecular histology 2020 Apr;51(2):161-171
Journal of molecular histology 2020 Apr;51(2):161-171
Long noncoding RNA MACC1-AS1 promotes the stemness of hepatocellular carcinoma cells by antagonizing miR-145.
Guo Y, Zhong J, Wu F, Zhan Z
The Journal of international medical research 2020 Apr;48(4):300060520920411
The Journal of international medical research 2020 Apr;48(4):300060520920411
LncRNA MIAT/miR-133a-3p axis regulates atrial fibrillation and atrial fibrillation-induced myocardial fibrosis.
Yao L, Zhou B, You L, Hu H, Xie R
Molecular biology reports 2020 Apr;47(4):2605-2617
Molecular biology reports 2020 Apr;47(4):2605-2617
Low-intensity pulsed ultrasound promotes the expression of immediate-early genes in mouse ST2 bone marrow stromal cells.
Tabuchi Y, Hasegawa H, Suzuki N, Furusawa Y, Hirano T, Nagaoka R, Takeuchi SI, Shiiba M, Mochizuki T
Journal of medical ultrasonics (2001) 2020 Apr;47(2):193-201
Journal of medical ultrasonics (2001) 2020 Apr;47(2):193-201
Down-regulation of lncRNA BLACAT1 inhibits ovarian cancer progression by suppressing the Wnt/β-catenin signaling pathway via regulating miR-519d-3p.
Yang H, Qi Y, Wang XL, Gu JJ, Shi TM
Molecular and cellular biochemistry 2020 Apr;467(1-2):95-105
Molecular and cellular biochemistry 2020 Apr;467(1-2):95-105
Rab22a is a novel prognostic marker for cell progression in breast cancer.
He M, Shen L, Jiang C, Gao G, Wang K, Jiao Y, Sun L, Cui Y, Ke Z, Yang Z
International journal of molecular medicine 2020 Apr;45(4):1037-1046
International journal of molecular medicine 2020 Apr;45(4):1037-1046
Sirtuin 2 Inhibition Attenuates Sevoflurane-Induced Learning and Memory Deficits in Developing Rats via Modulating Microglial Activation.
Wu Z, Zhang Y, Zhang Y, Zhao P
Cellular and molecular neurobiology 2020 Apr;40(3):437-446
Cellular and molecular neurobiology 2020 Apr;40(3):437-446
CFIm25-regulated lncRNA acv3UTR promotes gastric tumorigenesis via miR-590-5p/YAP1 axis.
Liu K, Wang BJ, Han W, Chi CH, Gu C, Wang Y, Fu X, Huang W, Liu Z, Song X
Oncogene 2020 Apr;39(15):3075-3088
Oncogene 2020 Apr;39(15):3075-3088
MiR-194-5p inhibited metastasis and EMT of nephroblastoma cells through targeting Crk.
Liu H, Ren SY, Qu Y, Liu C, Zhang Y, Li XQ, Ma H
The Kaohsiung journal of medical sciences 2020 Apr;36(4):265-273
The Kaohsiung journal of medical sciences 2020 Apr;36(4):265-273
MTH1 Inhibitor TH287 Suppresses Gastric Cancer Development Through the Regulation of PI3K/AKT Signaling.
Zhan D, Zhang X, Li J, Ding X, Cui Y, Jia J
Cancer biotherapy & radiopharmaceuticals 2020 Apr;35(3):223-232
Cancer biotherapy & radiopharmaceuticals 2020 Apr;35(3):223-232
Regulation of hepatic glutamine metabolism by miR-122.
Sengupta D, Cassel T, Teng KY, Aljuhani M, Chowdhary VK, Hu P, Zhang X, Fan TW, Ghoshal K
Molecular metabolism 2020 Apr;34:174-186
Molecular metabolism 2020 Apr;34:174-186
Different Serotypes of Adeno-Associated Virus Vector- and Lentivirus-Mediated Tropism in Choroid Plexus by Intracerebroventricular Delivery.
Chen X, He Y, Tian Y, Wang Y, Wu Z, Lan T, Wang H, Cheng K, Xie P
Human gene therapy 2020 Apr;31(7-8):440-447
Human gene therapy 2020 Apr;31(7-8):440-447
Nicotinamide riboside rescues angiotensin II-induced cerebral small vessel disease in mice.
Li CC, Chen WX, Wang J, Xia M, Jia ZC, Guo C, Tang XQ, Li MX, Yin Y, Liu X, Feng H
CNS neuroscience & therapeutics 2020 Apr;26(4):438-447
CNS neuroscience & therapeutics 2020 Apr;26(4):438-447
Estrogen accelerates heart regeneration by promoting the inflammatory response in zebrafish.
Xu S, Xie F, Tian L, Fallah S, Babaei F, Manno SHC, Manno FAM, Zhu L, Wong KF, Liang Y, Ramalingam R, Sun L, Wang X, Plumb R, Gethings L, Lam YW, Cheng SH
The Journal of endocrinology 2020 Apr;245(1):39-51
The Journal of endocrinology 2020 Apr;245(1):39-51
Potent USP10/13 antagonist spautin-1 suppresses melanoma growth via ROS-mediated DNA damage and exhibits synergy with cisplatin.
Guo J, Zhang J, Liang L, Liu N, Qi M, Zhao S, Su J, Liu J, Peng C, Chen X, Liu H
Journal of cellular and molecular medicine 2020 Apr;24(7):4324-4340
Journal of cellular and molecular medicine 2020 Apr;24(7):4324-4340
METTL3/YTHDF2 m(6) A axis promotes tumorigenesis by degrading SETD7 and KLF4 mRNAs in bladder cancer.
Xie H, Li J, Ying Y, Yan H, Jin K, Ma X, He L, Xu X, Liu B, Wang X, Zheng X, Xie L
Journal of cellular and molecular medicine 2020 Apr;24(7):4092-4104
Journal of cellular and molecular medicine 2020 Apr;24(7):4092-4104
MiR-210-3p-EphrinA3-PI3K/AKT axis regulates the progression of oral cancer.
Wang L, Song Y, Wang H, Liu K, Shao Z, Shang Z
Journal of cellular and molecular medicine 2020 Apr;24(7):4011-4022
Journal of cellular and molecular medicine 2020 Apr;24(7):4011-4022
Long noncoding RNA FBXL19-AS1 induces tumor growth and metastasis by sponging miR-203a-3p in lung adenocarcinoma.
Wang L, Zhang X, Liu Y, Xu S
Journal of cellular physiology 2020 Apr;235(4):3612-3625
Journal of cellular physiology 2020 Apr;235(4):3612-3625
Estradiol-17β regulates proliferation and apoptosis of sheep endometrial epithelial cells by regulating the relative abundance of YAP1.
An SY, Gao XX, Wang ZB, Liang YX, Wang ST, Xiao SH, Xia JT, You PH, Wang F, Zhang GM
Animal reproduction science 2020 Apr;215:106328
Animal reproduction science 2020 Apr;215:106328
Long non‑coding RNA MALAT1 regulates cholesterol accumulation in ox‑LDL‑induced macrophages via the microRNA‑17‑5p/ABCA1 axis.
Liu L, Tan L, Yao J, Yang L
Molecular medicine reports 2020 Apr;21(4):1761-1770
Molecular medicine reports 2020 Apr;21(4):1761-1770
C9orf72 associates with inactive Rag GTPases and regulates mTORC1-mediated autophagosomal and lysosomal biogenesis.
Wang M, Wang H, Tao Z, Xia Q, Hao Z, Prehn JHM, Zhen X, Wang G, Ying Z
Aging cell 2020 Apr;19(4):e13126
Aging cell 2020 Apr;19(4):e13126
Effects of propofol on LC3II and mTOR/p-mTOR expression during ischemia-reperfusion myocardium injury in rats with type 2 diabetes mellitus.
Wang Y, Zhang K, Qi X, Yang G, Wang H, Zhang Z, Yang B
Experimental and therapeutic medicine 2020 Apr;19(4):2441-2448
Experimental and therapeutic medicine 2020 Apr;19(4):2441-2448
Galantamine Inhibits Aβ(1-42)-Induced Neurotoxicity by Enhancing α7nAChR Expression as a Cargo Carrier for LC3 Binding and Aβ(1-42) Engulfment During Autophagic Degradation.
Lin MW, Chen YH, Yang HB, Lin CC, Hung SY
Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics 2020 Apr;17(2):676-689
Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics 2020 Apr;17(2):676-689
Ehrlichia chaffeensis TRP120-mediated ubiquitination and proteasomal degradation of tumor suppressor FBW7 increases oncoprotein stability and promotes infection.
Wang JY, Zhu B, Patterson LL, Rogan MR, Kibler CE, McBride JW
PLoS pathogens 2020 Apr;16(4):e1008541
PLoS pathogens 2020 Apr;16(4):e1008541
Potential role of full-length and nonfull-length progranulin in affecting aortic valve calcification.
Huang G, An L, Fan M, Zhang M, Chen B, Zhu M, Wu J, Liu Y, Wang Y, Huang Q, Shi Q, Weng Y
Journal of molecular and cellular cardiology 2020 Apr;141:93-104
Journal of molecular and cellular cardiology 2020 Apr;141:93-104
Overcoming acquired resistance of EGFR-mutant NSCLC cells to the third generation EGFR inhibitor, osimertinib, with the natural product honokiol.
Zang H, Qian G, Arbiser J, Owonikoko TK, Ramalingam SS, Fan S, Sun SY
Molecular oncology 2020 Apr;14(4):882-895
Molecular oncology 2020 Apr;14(4):882-895
3,4,5-Tri-O-caffeoylquinic acid methyl ester isolated from Lonicera japonica Thunb. Flower buds facilitates hepatitis B virus replication in HepG2.2.15 cells.
Wan H, Ge L, Xiao L, Li J, Wu W, Peng S, Huang J, Zhou B, Zeng X
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2020 Apr;138:111250
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2020 Apr;138:111250
Photobiomodulation by diffusing optical fiber on spinal cord: A feasibility study in piglet model.
Liang Z, Lei T, Wang S, Zuo X, Li K, Song J, Sun J, Zhang J, Zheng Q, Kang X, Ma Y, Hu X, Ding T, Wang Z
Journal of biophotonics 2020 Apr;13(4):e201960022
Journal of biophotonics 2020 Apr;13(4):e201960022
Tissue Transglutaminase contributes to myelin phagocytosis in interleukin-4-treated human monocyte-derived macrophages.
Sestito C, Brevé JJP, Bol JGJM, Wilhelmus MMM, Drukarch B, van Dam AM
Cytokine 2020 Apr;128:155024
Cytokine 2020 Apr;128:155024
Prazosin inhibits the proliferation and survival of acute myeloid leukaemia cells through down-regulating TNS1.
Sun X, Yang S, Song W
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Apr;124:109731
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Apr;124:109731
Circ-IGF1R inhibits cell invasion and migration in non-small cell lung cancer.
Xu Z, Xiang W, Chen W, Sun Y, Qin F, Wei J, Yuan L, Zheng L, Li S
Thoracic cancer 2020 Apr;11(4):875-887
Thoracic cancer 2020 Apr;11(4):875-887
Low-dose lithium feeding increases the SERCA2a-to-phospholamban ratio, improving SERCA function in murine left ventricles.
Hamstra SI, Kurgan N, Baranowski RW, Qiu L, Watson CJF, Messner HN, MacPherson REK, MacNeil AJ, Roy BD, Fajardo VA
Experimental physiology 2020 Apr;105(4):666-675
Experimental physiology 2020 Apr;105(4):666-675
Dexmedetomidine alleviates postoperative cognitive dysfunction through circular RNA in aged rats.
Cao C, Deng F, Hu Y
3 Biotech 2020 Apr;10(4):176
3 Biotech 2020 Apr;10(4):176
Small Nucleolar RNA, C/D Box 16 (SNORD16) Acts as a Potential Prognostic Biomarker in Colon Cancer.
He JY, Liu X, Qi ZH, Wang Q, Lu WQ, Zhang QT, He SY, Wang ZD
Dose-response : a publication of International Hormesis Society 2020 Apr-Jun;18(2):1559325820917829
Dose-response : a publication of International Hormesis Society 2020 Apr-Jun;18(2):1559325820917829
PGN and LTA from Staphylococcus aureus Induced Inflammation and Decreased Lactation through Regulating DNA Methylation and Histone H3 Acetylation in Bovine Mammary Epithelial Cells.
Wu Y, Chen J, Sun Y, Dong X, Wang Z, Chen J, Dong G
Toxins 2020 Apr 9;12(4)
Toxins 2020 Apr 9;12(4)
Caspase-8 Induces Lysosome-Associated Cell Death in Cancer Cells.
Zhong B, Liu M, Bai C, Ruan Y, Wang Y, Qiu L, Hong Y, Wang X, Li L, Li B
Molecular therapy : the journal of the American Society of Gene Therapy 2020 Apr 8;28(4):1078-1091
Molecular therapy : the journal of the American Society of Gene Therapy 2020 Apr 8;28(4):1078-1091
Type 3 adenylyl cyclase in the MOE is involved in learning and memory in mice.
Liu X, Zhou Y, Yang D, Li S, Liu X, Wang Z
Behavioural brain research 2020 Apr 6;383:112533
Behavioural brain research 2020 Apr 6;383:112533
α-Tubulin detyrosination impairs mitotic error correction by suppressing MCAK centromeric activity.
Ferreira LT, Orr B, Rajendraprasad G, Pereira AJ, Lemos C, Lima JT, Guasch Boldú C, Ferreira JG, Barisic M, Maiato H
The Journal of cell biology 2020 Apr 6;219(4)
The Journal of cell biology 2020 Apr 6;219(4)
Impaired autophagic flux contributes to muscle atrophy in obesity by affecting muscle degradation and regeneration.
Fan Z, Xiao Q
Biochemical and biophysical research communications 2020 Apr 30;525(2):462-468
Biochemical and biophysical research communications 2020 Apr 30;525(2):462-468
The cellular expression and proteolytic processing of the amyloid precursor protein is independent of TDP-43.
Hicks DA, Jones AC, Pickering-Brown SM, Hooper NM
Bioscience reports 2020 Apr 30;40(4)
Bioscience reports 2020 Apr 30;40(4)
METTL3 is essential for postnatal development of brown adipose tissue and energy expenditure in mice.
Wang Y, Gao M, Zhu F, Li X, Yang Y, Yan Q, Jia L, Xie L, Chen Z
Nature communications 2020 Apr 3;11(1):1648
Nature communications 2020 Apr 3;11(1):1648
Breast cancer-derived exosomes transmit lncRNA SNHG16 to induce CD73+γδ1 Treg cells.
Ni C, Fang QQ, Chen WZ, Jiang JX, Jiang Z, Ye J, Zhang T, Yang L, Meng FB, Xia WJ, Zhong M, Huang J
Signal transduction and targeted therapy 2020 Apr 29;5(1):41
Signal transduction and targeted therapy 2020 Apr 29;5(1):41
Dimethyl itaconate, an itaconate derivative, exhibits immunomodulatory effects on neuroinflammation in experimental autoimmune encephalomyelitis.
Kuo PC, Weng WT, Scofield BA, Paraiso HC, Brown DA, Wang PY, Yu IC, Yen JH
Journal of neuroinflammation 2020 Apr 29;17(1):138
Journal of neuroinflammation 2020 Apr 29;17(1):138
ACE2 correlated with immune infiltration serves as a prognostic biomarker in endometrial carcinoma and renal papillary cell carcinoma: implication for COVID-19.
Yang J, Li H, Hu S, Zhou Y
Aging 2020 Apr 27;12(8):6518-6535
Aging 2020 Apr 27;12(8):6518-6535
PENK inhibits osteosarcoma cell migration by activating the PI3K/Akt signaling pathway.
Zhang HP, Yu ZL, Wu BB, Sun FR
Journal of orthopaedic surgery and research 2020 Apr 25;15(1):162
Journal of orthopaedic surgery and research 2020 Apr 25;15(1):162
Inhibition of cGAS-Mediated Interferon Response Facilitates Transgene Expression.
Fu Y, Fang Y, Lin Z, Yang L, Zheng L, Hu H, Yu T, Huang B, Chen S, Wang H, Xu S, Bao W, Chen Q, Sun L
iScience 2020 Apr 24;23(4):101026
iScience 2020 Apr 24;23(4):101026
4,5-di-O-caffeoylquinic acid methyl ester isolated from Lonicera japonica Thunb. targets the Keap1/Nrf2 pathway to attenuate H(2)O(2)-induced liver oxidative damage in HepG2 cells.
Xiao L, Liang S, Ge L, Wan H, Wu W, Fei J, Wu S, Zhou B, Zeng X
Phytomedicine : international journal of phytotherapy and phytopharmacology 2020 Apr 23;70:153219
Phytomedicine : international journal of phytotherapy and phytopharmacology 2020 Apr 23;70:153219
Pathogenic Variants in CEP85L Cause Sporadic and Familial Posterior Predominant Lissencephaly.
Tsai MH, Muir AM, Wang WJ, Kang YN, Yang KC, Chao NH, Wu MF, Chang YC, Porter BE, Jansen LA, Sebire G, Deconinck N, Fan WL, Su SC, Chung WH, Almanza Fuerte EP, Mehaffey MG, University of Washington Center for Mendelian Genomics, Ng CC, Chan CK, Lim KS, Leventer RJ, Lockhart PJ, Riney K, Damiano JA, Hildebrand MS, Mirzaa GM, Dobyns WB, Berkovic SF, Scheffer IE, Tsai JW, Mefford HC
Neuron 2020 Apr 22;106(2):237-245.e8
Neuron 2020 Apr 22;106(2):237-245.e8
The potential role of Krüppel-like factor 13 (Aj-klf13) in the intestine regeneration of sea cucumber Apostichopus japonicus.
Chen L, Yao F, Qin Y, Shao Y, Fang L, Yu X, Wang S, Hou L
Gene 2020 Apr 20;735:144407
Gene 2020 Apr 20;735:144407
Carnosol inhibits inflammasome activation by directly targeting HSP90 to treat inflammasome-mediated diseases.
Shi W, Xu G, Zhan X, Gao Y, Wang Z, Fu S, Qin N, Hou X, Ai Y, Wang C, He T, Liu H, Chen Y, Liu Y, Wang J, Niu M, Guo Y, Xiao X, Bai Z
Cell death & disease 2020 Apr 20;11(4):252
Cell death & disease 2020 Apr 20;11(4):252
Sitagliptin Inhibits Extracellular Matrix Accumulation and Proliferation in Lung Fibroblasts.
Liu X, Zhang T, Zhang C
Medical science monitor : international medical journal of experimental and clinical research 2020 Apr 17;26:e922644
Medical science monitor : international medical journal of experimental and clinical research 2020 Apr 17;26:e922644
Alamandine attenuates hepatic fibrosis by regulating autophagy induced by NOX4-dependent ROS.
Huang Y, Li Y, Lou A, Wang GZ, Hu Y, Zhang Y, Huang W, Wang J, Li Y, Zhu X, Chen T, Lin J, Meng Y, Li X
Clinical science (London, England : 1979) 2020 Apr 17;134(7):853-869
Clinical science (London, England : 1979) 2020 Apr 17;134(7):853-869
Reverse Genetics Reveals a Role of Rotavirus VP3 Phosphodiesterase Activity in Inhibiting RNase L Signaling and Contributing to Intestinal Viral Replication In Vivo.
Song Y, Feng N, Sanchez-Tacuba L, Yasukawa LL, Ren L, Silverman RH, Ding S, Greenberg HB
Journal of virology 2020 Apr 16;94(9)
Journal of virology 2020 Apr 16;94(9)
Induced CD10 expression during monocyte-to-macrophage differentiation identifies a unique subset of macrophages in pancreatic ductal adenocarcinoma.
Huang X, He C, Lin G, Lu L, Xing K, Hua X, Sun S, Mao Y, Song Y, Wang J, Li S
Biochemical and biophysical research communications 2020 Apr 16;524(4):1064-1071
Biochemical and biophysical research communications 2020 Apr 16;524(4):1064-1071
Zhx2 Accelerates Sepsis by Promoting Macrophage Glycolysis via Pfkfb3.
Wang Z, Kong L, Tan S, Zhang Y, Song X, Wang T, Lin Q, Wu Z, Xiang P, Li C, Gao L, Liang X, Ma C
Journal of immunology (Baltimore, Md. : 1950) 2020 Apr 15;204(8):2232-2241
Journal of immunology (Baltimore, Md. : 1950) 2020 Apr 15;204(8):2232-2241
NOD1 Promotes Antiviral Signaling by Binding Viral RNA and Regulating the Interaction of MDA5 and MAVS.
Wu XM, Zhang J, Li PW, Hu YW, Cao L, Ouyang S, Bi YH, Nie P, Chang MX
Journal of immunology (Baltimore, Md. : 1950) 2020 Apr 15;204(8):2216-2231
Journal of immunology (Baltimore, Md. : 1950) 2020 Apr 15;204(8):2216-2231
The circular RNA CDR1as regulate cell proliferation via TMED2 and TMED10.
Yang X, Li S, Wu Y, Ge F, Chen Y, Xiong Q
BMC cancer 2020 Apr 15;20(1):312
BMC cancer 2020 Apr 15;20(1):312
Betulinic Acid-Mediated Tuning of PERK/CHOP Signaling by Sp1 Inhibition as a Novel Therapeutic Strategy for Glioblastoma.
Lo WL, Hsu TI, Yang WB, Kao TJ, Wu MH, Huang YN, Yeh SH, Chuang JY
Cancers 2020 Apr 15;12(4)
Cancers 2020 Apr 15;12(4)
Interleukin 26 Skews Macrophage Polarization Towards M1 Phenotype by Activating cJUN and the NF-κB Pathway.
Lin YH, Wang YH, Peng YJ, Liu FC, Lin GJ, Huang SH, Sytwu HK, Cheng CP
Cells 2020 Apr 10;9(4)
Cells 2020 Apr 10;9(4)
Doxorubicin-polyglycerol-nanodiamond conjugates disrupt STAT3/IL-6-mediated reciprocal activation loop between glioblastoma cells and astrocytes.
Chen Z, Yuan SJ, Li K, Zhang Q, Li TF, An HC, Xu HZ, Yue Y, Han M, Xu YH, Komatsu N, Zhao L, Chen X
Journal of controlled release : official journal of the Controlled Release Society 2020 Apr 10;320:469-483
Journal of controlled release : official journal of the Controlled Release Society 2020 Apr 10;320:469-483
A Novel Rhynchophylline Analog, Y396, Inhibits Endothelial Dysfunction Induced by Oxidative Stress in Diabetes Through Epidermal Growth Factor Receptor.
Wang ZJ, Chang LL, Wu J, Pan HM, Zhang QY, Wang MJ, Xin XM, Luo SS, Chen JA, Gu XF, Guo W, Zhu YZ
Antioxidants & redox signaling 2020 Apr 10;32(11):743-765
Antioxidants & redox signaling 2020 Apr 10;32(11):743-765
The HIV-1 capsid-binding host factor CPSF6 is post-transcriptionally regulated by the cellular microRNA miR-125b.
Chaudhuri E, Dash S, Balasubramaniam M, Padron A, Holland J, Sowd GA, Villalta F, Engelman AN, Pandhare J, Dash C
The Journal of biological chemistry 2020 Apr 10;295(15):5081-5094
The Journal of biological chemistry 2020 Apr 10;295(15):5081-5094
Paraoxonase 3 functions as a chaperone to decrease functional expression of the epithelial sodium channel.
Shi S, Montalbetti N, Wang X, Rush BM, Marciszyn AL, Baty CJ, Tan RJ, Carattino MD, Kleyman TR
The Journal of biological chemistry 2020 Apr 10;295(15):4950-4962
The Journal of biological chemistry 2020 Apr 10;295(15):4950-4962
FTO promotes cell proliferation and migration in esophageal squamous cell carcinoma through up-regulation of MMP13.
Liu S, Huang M, Chen Z, Chen J, Chao Q, Yin X, Quan M
Experimental cell research 2020 Apr 1;389(1):111894
Experimental cell research 2020 Apr 1;389(1):111894
Adipose-derived exosomes protect the pulmonary endothelial barrier in ventilator-induced lung injury by inhibiting the TRPV4/Ca(2+) signaling pathway.
Yu Q, Wang D, Wen X, Tang X, Qi D, He J, Zhao Y, Deng W, Zhu T
American journal of physiology. Lung cellular and molecular physiology 2020 Apr 1;318(4):L723-L741
American journal of physiology. Lung cellular and molecular physiology 2020 Apr 1;318(4):L723-L741
miR-524-5p inhibits angiogenesis through targeting WNK1 in colon cancer cells.
Li X, Li Z, Zhu Y, Li Z, Yao L, Zhang L, Yuan L, Shang Y, Liu J, Li C
American journal of physiology. Gastrointestinal and liver physiology 2020 Apr 1;318(4):G827-G839
American journal of physiology. Gastrointestinal and liver physiology 2020 Apr 1;318(4):G827-G839
OTUD1 Negatively Regulates Type I IFN Induction by Disrupting Noncanonical Ubiquitination of IRF3.
Zhang Z, Wang D, Wang P, Zhao Y, You F
Journal of immunology (Baltimore, Md. : 1950) 2020 Apr 1;204(7):1904-1918
Journal of immunology (Baltimore, Md. : 1950) 2020 Apr 1;204(7):1904-1918
Lanthanum chloride impairs spatial learning and memory by inducing [Ca(2+)](m) overload, mitochondrial fission-fusion disorder and excessive mitophagy in hippocampal nerve cells of rats.
Yu M, Yang J, Gao X, Sun W, Liu S, Han Y, Lu X, Jin C, Wu S, Cai Y
Metallomics : integrated biometal science 2020 Apr 1;12(4):592-606
Metallomics : integrated biometal science 2020 Apr 1;12(4):592-606
The protective effects of β-sitosterol and vermicularin from Thamnolia vermicularis (Sw.) Ach. against skin aging in vitro.
Haiyuan YU, Shen X, Liu D, Hong M, Lu Y
Anais da Academia Brasileira de Ciencias 2019;91(4):e20181088
Anais da Academia Brasileira de Ciencias 2019;91(4):e20181088
Tumor-associated macrophages (TAMs) depend on Shp2 for their anti-tumor roles in colorectal cancer.
Wang S, Yao Y, Li H, Zheng G, Lu S, Chen W
American journal of cancer research 2019;9(9):1957-1969
American journal of cancer research 2019;9(9):1957-1969
Progerin accumulation in nucleus pulposus cells impairs mitochondrial function and induces intervertebral disc degeneration and therapeutic effects of sulforaphane.
Xu X, Wang D, Zheng C, Gao B, Fan J, Cheng P, Liu B, Yang L, Luo Z
Theranostics 2019;9(8):2252-2267
Theranostics 2019;9(8):2252-2267
Overexpression of MEF2D contributes to oncogenic malignancy and chemotherapeutic resistance in ovarian carcinoma.
Li X, Zhang Y, Chai X, Zhou S, Zhang H, He J, Zhou R, Cai L, Chen L, Tao G
American journal of cancer research 2019;9(5):887-905
American journal of cancer research 2019;9(5):887-905
Changes in the intestinal microecology induced by bacillus subtilis inhibit the occurrence of ulcerative colitis and associated cancers: a study on the mechanisms.
Wu C, Ouyang M, Guo Q, Jia J, Liu R, Jiang Y, Wu M, Shen S
American journal of cancer research 2019;9(5):872-886
American journal of cancer research 2019;9(5):872-886
Collaborative ISL1/GATA3 interaction in controlling neuroblastoma oncogenic pathways overlapping with but distinct from MYCN.
Zhang Q, Zhang Q, Jiang X, Ye Y, Liao H, Zhu F, Yan J, Luo L, Tian L, Jiang C, Chen Y, Liang X, Sun Y
Theranostics 2019;9(4):986-1000
Theranostics 2019;9(4):986-1000
CACYBP Enhances Cytoplasmic Retention of P27(Kip1) to Promote Hepatocellular Carcinoma Progression in the Absence of RNF41 Mediated Degradation.
Lian YF, Huang YL, Zhang YJ, Chen DM, Wang JL, Wei H, Bi YH, Jiang ZW, Li P, Chen MS, Huang YH
Theranostics 2019;9(26):8392-8408
Theranostics 2019;9(26):8392-8408
Inhibition of SMYD2 suppresses tumor progression by down-regulating microRNA-125b and attenuates multi-drug resistance in renal cell carcinoma.
Yan L, Ding B, Liu H, Zhang Y, Zeng J, Hu J, Yao W, Yu G, An R, Chen Z, Ye Z, Xing J, Xiao K, Wu L, Xu H
Theranostics 2019;9(26):8377-8391
Theranostics 2019;9(26):8377-8391
A Compound AC1Q3QWB Selectively Disrupts HOTAIR-Mediated Recruitment of PRC2 and Enhances Cancer Therapy of DZNep.
Li Y, Ren Y, Wang Y, Tan Y, Wang Q, Cai J, Zhou J, Yang C, Zhao K, Yi K, Jin W, Wang L, Liu M, Yang J, Li M, Kang C
Theranostics 2019;9(16):4608-4623
Theranostics 2019;9(16):4608-4623
Autophagy impairment contributes to PBDE-47-induced developmental neurotoxicity and its relationship with apoptosis.
Li P, Ma R, Dong L, Liu L, Zhou G, Tian Z, Zhao Q, Xia T, Zhang S, Wang A
Theranostics 2019;9(15):4375-4390
Theranostics 2019;9(15):4375-4390
Long noncoding RNA GAS5 inhibits metastasis by targeting miR-182/ANGPTL1 in hepatocellular carcinoma.
Chen F, Li Y, Li M, Wang L
American journal of cancer research 2019;9(1):108-121
American journal of cancer research 2019;9(1):108-121
CRISPRa-mediated FOXP3 gene upregulation in mammalian cells.
Forstnerič V, Oven I, Ogorevc J, Lainšček D, Praznik A, Lebar T, Jerala R, Horvat S
Cell & bioscience 2019;9:93
Cell & bioscience 2019;9:93
Aurora-A Induces Chemoresistance Through Activation of the AKT/mTOR Pathway in Endometrial Cancer.
Wu J, Cheng Z, Xu X, Fu J, Wang K, Liu T, Wu C, Kong X, Yang Q, Yan G, Zhou H
Frontiers in oncology 2019;9:422
Frontiers in oncology 2019;9:422
Antitumor Effects of Berberine on Gliomas via Inactivation of Caspase-1-Mediated IL-1β and IL-18 Release.
Tong L, Xie C, Wei Y, Qu Y, Liang H, Zhang Y, Xu T, Qian X, Qiu H, Deng H
Frontiers in oncology 2019;9:364
Frontiers in oncology 2019;9:364
A Novel Citrullinated Modification of Histone 3 and Its Regulatory Mechanisms Related to IPO-38 Antibody-Labeled Protein.
Song S, Xiang Z, Li J, Ji J, Yan R, Zhu Z, Yu Y
Frontiers in oncology 2019;9:304
Frontiers in oncology 2019;9:304
Nociceptin Receptor Is Overexpressed in Non-small Cell Lung Cancer and Predicts Poor Prognosis.
Wang K, Zheng Y, Yang Y, Wang J, Li B, Wei F, Zhao H, Ren X
Frontiers in oncology 2019;9:235
Frontiers in oncology 2019;9:235
Identification of a Two-Gene (PML-EPB41) Signature With Independent Prognostic Value in Osteosarcoma.
Liu S, Liu J, Yu X, Shen T, Fu Q
Frontiers in oncology 2019;9:1578
Frontiers in oncology 2019;9:1578
PA28α/β Promote Breast Cancer Cell Invasion and Metastasis via Down-Regulation of CDK15.
Li S, Dai X, Gong K, Song K, Tai F, Shi J
Frontiers in oncology 2019;9:1283
Frontiers in oncology 2019;9:1283
Long Non-coding RNA SNHG12 Functions as a Competing Endogenous RNA to Regulate MDM4 Expression by Sponging miR-129-5p in Clear Cell Renal Cell Carcinoma.
Wu Z, Chen D, Wang K, Cao C, Xu X
Frontiers in oncology 2019;9:1260
Frontiers in oncology 2019;9:1260
The Tumor Suppressor Role of Zinc Finger Protein 671 (ZNF671) in Multiple Tumors Based on Cancer Single-Cell Sequencing.
Zhang J, Luo J, Jiang H, Xie T, Zheng J, Tian Y, Li R, Wang B, Lin J, Xu A, Huang X, Yuan Y
Frontiers in oncology 2019;9:1214
Frontiers in oncology 2019;9:1214
MRPS30-DT Knockdown Inhibits Breast Cancer Progression by Targeting Jab1/Cops5.
Wu B, Pan Y, Liu G, Yang T, Jin Y, Zhou F, Wei Y
Frontiers in oncology 2019;9:1170
Frontiers in oncology 2019;9:1170
FA2H Exhibits Tumor Suppressive Roles on Breast Cancers via Cancer Stemness Control.
Dai X, Zhang S, Cheng H, Cai D, Chen X, Huang Z
Frontiers in oncology 2019;9:1089
Frontiers in oncology 2019;9:1089
SEMA3C Promotes Cervical Cancer Growth and Is Associated With Poor Prognosis.
Liu R, Shuai Y, Luo J, Zhang Z
Frontiers in oncology 2019;9:1035
Frontiers in oncology 2019;9:1035
Heatstroke-induced hepatocyte exosomes promote liver injury by activating the NOD-like receptor signaling pathway in mice.
Li Y, Zhu X, Zhang M, Tong H, Su L
PeerJ 2019;7:e8216
PeerJ 2019;7:e8216
Structural basis for the recognition of K48-linked Ub chain by proteasomal receptor Rpn13.
Liu Z, Dong X, Yi HW, Yang J, Gong Z, Wang Y, Liu K, Zhang WP, Tang C
Cell discovery 2019;5:19
Cell discovery 2019;5:19
Loss of the Golgi Matrix Protein 130 Cause Aberrant IgA1 Glycosylation in IgA Nephropathy.
Wang C, Ye M, Zhao Q, Xia M, Liu D, He L, Chen G, Peng Y, Liu H
American journal of nephrology 2019;49(4):307-316
American journal of nephrology 2019;49(4):307-316
Hsa_circ_001569 is an unfavorable prognostic factor and promotes cell proliferation and metastasis by modulating PI3K-AKT pathway in breast cancer.
Xu JH, Wang Y, Xu D
Cancer biomarkers : section A of Disease markers 2019;25(2):193-201
Cancer biomarkers : section A of Disease markers 2019;25(2):193-201
Long noncoding RNA glutathione peroxidase 3-antisense inhibits lens epithelial cell apoptosis by upregulating glutathione peroxidase 3 expression in age-related cataract.
Tu Y, Li L, Qin B, Wu J, Cheng T, Kang L, Guan H
Molecular vision 2019;25:734-744
Molecular vision 2019;25:734-744
The long noncoding RNA LINC00483 promotes lung adenocarcinoma progression by sponging miR-204-3p.
Yang S, Liu T, Sun Y, Liang X
Cellular & molecular biology letters 2019;24:70
Cellular & molecular biology letters 2019;24:70
Effect of MicroRNA-20a on Osteogenic Differentiation of Human Adipose Tissue-Derived Stem Cells.
Luo T, Yang X, Sun Y, Huang X, Zou L, Liu J
Cells, tissues, organs 2019;208(3-4):148-157
Cells, tissues, organs 2019;208(3-4):148-157
Xiaokeping Mixture Attenuates Diabetic Kidney Disease by Modulating TGF-β/Smad Pathway in db/db Mice.
Yang B, Xia Z, Xin C, Ma C, Zhang F
Evidence-based complementary and alternative medicine : eCAM 2019;2019:9241896
Evidence-based complementary and alternative medicine : eCAM 2019;2019:9241896
Mangiferin Prevents TBHP-Induced Apoptosis and ECM Degradation in Mouse Osteoarthritic Chondrocytes via Restoring Autophagy and Ameliorates Murine Osteoarthritis.
Li Y, Wu Y, Jiang K, Han W, Zhang J, Xie L, Liu Y, Xiao J, Wang X
Oxidative medicine and cellular longevity 2019;2019:8783197
Oxidative medicine and cellular longevity 2019;2019:8783197
A Peptide Analogue of Selectin Ligands Attenuated Atherosclerosis by Inhibiting Monocyte Activation.
Ye Z, Zhang S, Liu Y, Wang S, Zhang J, Huang R
Mediators of inflammation 2019;2019:8709583
Mediators of inflammation 2019;2019:8709583
Modulations of Histone Deacetylase 2 Offer a Protective Effect through the Mitochondrial Apoptosis Pathway in Acute Liver Failure.
Wang Y, Yang F, Jiao FZ, Chen Q, Zhang WB, Wang LW, Gong ZJ
Oxidative medicine and cellular longevity 2019;2019:8173016
Oxidative medicine and cellular longevity 2019;2019:8173016
Therapeutic Effects of Human Urine-Derived Stem Cells in a Rat Model of Cisplatin-Induced Acute Kidney Injury In Vivo and In Vitro.
Sun B, Luo X, Yang C, Liu P, Yang Y, Dong X, Yang Z, Xu J, Zhang Y, Li L
Stem cells international 2019;2019:8035076
Stem cells international 2019;2019:8035076
Targeting INHBA in Ovarian Cancer Cells Suppresses Cancer Xenograft Growth by Attenuating Stromal Fibroblast Activation.
Li X, Yang Z, Xu S, Wang Z, Jin P, Yang X, Zhang Z, Wang Y, Wei X, Fang T, Gao Q
Disease markers 2019;2019:7275289
Disease markers 2019;2019:7275289
Abnormal Ribosome Biogenesis Partly Induced p53-Dependent Aortic Medial Smooth Muscle Cell Apoptosis and Oxidative Stress.
Wu Q, Hong J, Wang Z, Hu J, Chen R, Hu Z, Li B, Hu X, Zhang Z, Ruan Y
Oxidative medicine and cellular longevity 2019;2019:7064319
Oxidative medicine and cellular longevity 2019;2019:7064319
Pretreatment with AM1241 Enhances the Analgesic Effect of Intrathecally Administrated Mesenchymal Stem Cells.
Xie J, Ren J, Liu N, Wu C, Xiao D, Luo H, Du J
Stem cells international 2019;2019:7025473
Stem cells international 2019;2019:7025473
Effect of YAP on an Immortalized Periodontal Ligament Stem Cell Line.
Chen X, Wang Q, Gu K, Li A, Fu X, Wang Y, Gu W, Wen Y
Stem cells international 2019;2019:6804036
Stem cells international 2019;2019:6804036
Bufei Qingyu Granules Inhibit the Development of Systemic Sclerosis via Notch-1/Jagged-2 Signaling Pathway.
Su M, Tian F, Ouyang B, Wu X, Guo F, Chen H, Zhu X, Chen J, Qian X
Evidence-based complementary and alternative medicine : eCAM 2019;2019:6709278
Evidence-based complementary and alternative medicine : eCAM 2019;2019:6709278
Melatonin Rescued Reactive Oxygen Species-Impaired Osteogenesis of Human Bone Marrow Mesenchymal Stem Cells in the Presence of Tumor Necrosis Factor-Alpha.
Qiu X, Wang X, Qiu J, Zhu Y, Liang T, Gao B, Wu Z, Lian C, Peng Y, Liang A, Su P, Huang D
Stem cells international 2019;2019:6403967
Stem cells international 2019;2019:6403967
Hepatitis B Virus X Protein-Induced RORγ Expression to Promote the Migration and Proliferation of Hepatocellular Carcinoma.
Huang Y, Liang H, He C, Peng F
BioMed research international 2019;2019:5407126
BioMed research international 2019;2019:5407126
Identification of Upregulated HNRNPs Associated with Poor Prognosis in Pancreatic Cancer.
Qiao L, Xie N, Bai Y, Li Y, Shi Y, Wang J, Liu N
BioMed research international 2019;2019:5134050
BioMed research international 2019;2019:5134050
N-Acetylcysteine Attenuates Cisplatin-Induced Acute Kidney Injury by Inhibiting the C5a Receptor.
Huang S, You J, Wang K, Li Y, Zhang Y, Wei H, Liang X, Liu Y
BioMed research international 2019;2019:4805853
BioMed research international 2019;2019:4805853
NANOG Attenuates Hair Follicle-Derived Mesenchymal Stem Cell Senescence by Upregulating PBX1 and Activating AKT Signaling.
Liu F, Shi J, Zhang Y, Lian A, Han X, Zuo K, Liu M, Zheng T, Zou F, Liu X, Jin M, Mu Y, Li G, Su G, Liu J
Oxidative medicine and cellular longevity 2019;2019:4286213
Oxidative medicine and cellular longevity 2019;2019:4286213
Cul4a as a New Interaction Protein of PARP1 Inhibits Oxidative Stress-Induced H9c2 Cell Apoptosis.
Ye N, Zhang N, Zhang Y, Qian H, Wu B, Sun Y
Oxidative medicine and cellular longevity 2019;2019:4273261
Oxidative medicine and cellular longevity 2019;2019:4273261
Bu Shen Zhu Yun Decoction Improves Endometrial Receptivity via VEGFR-2-Mediated Angiogenesis.
Li L, Jiang H, Wei X, Geng D, He M, Du H
Evidence-based complementary and alternative medicine : eCAM 2019;2019:3949824
Evidence-based complementary and alternative medicine : eCAM 2019;2019:3949824
Loss of SDC1 Expression Is Associated with Poor Prognosis of Colorectal Cancer Patients in Northern China.
Li K, Li L, Wu X, Yu J, Ma H, Zhang R, Li Y, Wang W
Disease markers 2019;2019:3768708
Disease markers 2019;2019:3768708
Genetically Modified Porcine Mesenchymal Stem Cells by Lentiviral Tbx18 Create a Biological Pacemaker.
Hu Y, Li N, Liu L, Zhang H, Xue X, Shao X, Zhang Y, Lang X
Stem cells international 2019;2019:3621314
Stem cells international 2019;2019:3621314
Protocatechuic Acid-Mediated miR-219a-5p Activation Inhibits the p66shc Oxidant Pathway to Alleviate Alcoholic Liver Injury.
Fu R, Zhou J, Wang R, Sun R, Feng D, Wang Z, Zhao Y, Lv L, Tian X, Yao J
Oxidative medicine and cellular longevity 2019;2019:3527809
Oxidative medicine and cellular longevity 2019;2019:3527809
Upregulation of UCP2 Expression Protects against LPS-Induced Oxidative Stress and Apoptosis in Cardiomyocytes.
Huang J, Peng W, Zheng Y, Hao H, Li S, Yao Y, Ding Y, Zhang J, Lyu J, Zeng Q
Oxidative medicine and cellular longevity 2019;2019:2758262
Oxidative medicine and cellular longevity 2019;2019:2758262
Identification of CTRP1 as a Prognostic Biomarker and Oncogene in Human Glioblastoma.
Chen L, Su G
BioMed research international 2019;2019:2582416
BioMed research international 2019;2019:2582416
A regulatory circuit of circ-MTO1/miR-17/QKI-5 inhibits the proliferation of lung adenocarcinoma.
Zhang B, Chen M, Jiang N, Shi K, Qian R
Cancer biology & therapy 2019;20(8):1127-1135
Cancer biology & therapy 2019;20(8):1127-1135
Long non-coding RNA ARAP1-AS1 promotes the progression of bladder cancer by regulating miR-4735-3p/NOTCH2 axis.
Teng J, Ai X, Jia Z, Wang K, Guan Y, Guo Y
Cancer biology & therapy 2019;20(4):552-561
Cancer biology & therapy 2019;20(4):552-561
The m(6)A eraser FTO facilitates proliferation and migration of human cervical cancer cells.
Zou D, Dong L, Li C, Yin Z, Rao S, Zhou Q
Cancer cell international 2019;19:321
Cancer cell international 2019;19:321
The long noncoding RNA PCGEM1 promotes cell proliferation, migration and invasion via targeting the miR-182/FBXW11 axis in cervical cancer.
Zhang Q, Zheng J, Liu L
Cancer cell international 2019;19:304
Cancer cell international 2019;19:304
LncRNA DANCR promotes the proliferation, migration, and invasion of tongue squamous cell carcinoma cells through miR-135a-5p/KLF8 axis.
Zheng Y, Zheng B, Meng X, Yan Y, He J, Liu Y
Cancer cell international 2019;19:302
Cancer cell international 2019;19:302
Strand-specific miR-28-3p and miR-28-5p have differential effects on nasopharyngeal cancer cells proliferation, apoptosis, migration and invasion.
Lv Y, Yang H, Ma X, Wu G
Cancer cell international 2019;19:187
Cancer cell international 2019;19:187
Methods for Monitoring Autophagy in Silkworm Organs.
Montali A, Casartelli M, Bruno D, Grimaldi A, Tettamanti G
Methods in molecular biology (Clifton, N.J.) 2019;1854:159-174
Methods in molecular biology (Clifton, N.J.) 2019;1854:159-174
MicroRNA-29a is a key regulon that regulates BRD4 and mitigates liver fibrosis in mice by inhibiting hepatic stellate cell activation.
Huang YH, Kuo HC, Yang YL, Wang FS
International journal of medical sciences 2019;16(2):212-220
International journal of medical sciences 2019;16(2):212-220
LncRNA SNHG6 promotes proliferation, invasion and migration in colorectal cancer cells by activating TGF-β/Smad signaling pathway via targeting UPF1 and inducing EMT via regulation of ZEB1.
Wang X, Lai Q, He J, Li Q, Ding J, Lan Z, Gu C, Yan Q, Fang Y, Zhao X, Liu S
International journal of medical sciences 2019;16(1):51-59
International journal of medical sciences 2019;16(1):51-59
Ccr7 null mice are protected against diet-induced obesity via Ucp1 upregulation and enhanced energy expenditure.
Sano T, Sanada T, Sotomaru Y, Shinjo T, Iwashita M, Yamashita A, Fukuda T, Sanui T, Asano T, Kanematsu T, Nishimura F
Nutrition & metabolism 2019;16:43
Nutrition & metabolism 2019;16:43
Hypericin maintians PDX1 expression via the Erk pathway and protects islet β-cells against glucotoxicity and lipotoxicity.
Liang C, Hao F, Yao X, Qiu Y, Liu L, Wang S, Yu C, Song Z, Bao Y, Yi J, Huang Y, Wu Y, Zheng L, Sun Y, Wang G, Yang X, Yang S, Sun L, Li Y
International journal of biological sciences 2019;15(7):1472-1487
International journal of biological sciences 2019;15(7):1472-1487
KLF4-Mediated CDH3 Upregulation Suppresses Human Hepatoma Cell Growth and Migration via GSK-3β Signaling.
Li L, Yu S, Wu Q, Dou N, Li Y, Gao Y
International journal of biological sciences 2019;15(5):953-961
International journal of biological sciences 2019;15(5):953-961
Taurine Transporter Regulates Adipogenic Differentiation of Human Adipose-Derived Stem Cells through Affecting Wnt/β-catenin Signaling Pathway.
Hou X, Wang Z, Ding F, He Y, Wang P, Liu X, Xu F, Wang J, Yang Y
International journal of biological sciences 2019;15(5):1104-1112
International journal of biological sciences 2019;15(5):1104-1112
Upregulated MMP28 in Hepatocellular Carcinoma Promotes Metastasis via Notch3 Signaling and Predicts Unfavorable Prognosis.
Zhou J, Zheng X, Feng M, Mo Z, Shan Y, Wang Y, Jin J
International journal of biological sciences 2019;15(4):812-825
International journal of biological sciences 2019;15(4):812-825
Inhibition of Heme Oxygenase-1 enhances hyperthermia-induced autophagy and antiviral effect.
Yang Y, Wang HX, Zhang L, Huo W, Li XD, Qi RQ, Song XY, Wei S, Gao XH, Han S, Cao L
International journal of biological sciences 2019;15(3):568-578
International journal of biological sciences 2019;15(3):568-578
MiR-93 regulates vascular smooth muscle cell proliferation, and neointimal formation through targeting Mfn2.
Feng S, Gao L, Zhang D, Tian X, Kong L, Shi H, Wu L, Huang Z, Du B, Liang C, Zhang Y, Yao R
International journal of biological sciences 2019;15(12):2615-2626
International journal of biological sciences 2019;15(12):2615-2626
Muscle Injury Associated Elevated Oxidative Stress and Abnormal Myogenesis in Patients with Idiopathic Scoliosis.
Li J, Tang M, Yang G, Wang L, Gao Q, Zhang H
International journal of biological sciences 2019;15(12):2584-2595
International journal of biological sciences 2019;15(12):2584-2595
Resveratrol induced premature senescence and inhibited epithelial-mesenchymal transition of cancer cells via induction of tumor suppressor Rad9.
Chen KY, Chen CC, Chang YC, Chang MC
PloS one 2019;14(7):e0219317
PloS one 2019;14(7):e0219317
Progranulin deficiency leads to reduced glucocerebrosidase activity.
Zhou X, Paushter DH, Pagan MD, Kim D, Nunez Santos M, Lieberman RL, Overkleeft HS, Sun Y, Smolka MB, Hu F
PloS one 2019;14(7):e0212382
PloS one 2019;14(7):e0212382
Radiotherapy resistance acquisition in Glioblastoma. Role of SOCS1 and SOCS3.
Ventero MP, Fuentes-Baile M, Quereda C, Perez-Valeciano E, Alenda C, Garcia-Morales P, Esposito D, Dorado P, Manuel Barbera V, Saceda M
PloS one 2019;14(2):e0212581
PloS one 2019;14(2):e0212581
P16 methylation increases the sensitivity of cancer cells to the CDK4/6 inhibitor palbociclib.
Li P, Zhang X, Gu L, Zhou J, Deng D
PloS one 2019;14(10):e0223084
PloS one 2019;14(10):e0223084
Porous Se@SiO(2) nanospheres attenuate ischemia/reperfusion (I/R)-induced acute kidney injury (AKI) and inflammation by antioxidative stress.
Zheng Z, Deng G, Qi C, Xu Y, Liu X, Zhao Z, Zhang Z, Chu Y, Wu H, Liu J
International journal of nanomedicine 2019;14:215-229
International journal of nanomedicine 2019;14:215-229
Long-Term Effects of Zinc Deficiency and Zinc Supplementation on Developmental Seizure-Induced Brain Damage and the Underlying GPR39/ZnT-3 and MBP Expression in the Hippocampus.
Chen NN, Zhao DJ, Sun YX, Wang DD, Ni H
Frontiers in neuroscience 2019;13:920
Frontiers in neuroscience 2019;13:920
Effects of Acupuncture on Behavioral Stereotypies and Brain Dopamine System in Mice as a Model of Tourette Syndrome.
Lin L, Yu L, Xiang H, Hu X, Yuan X, Zhu H, Li H, Zhang H, Hou T, Cao J, Wu S, Su W, Li M
Frontiers in behavioral neuroscience 2019;13:239
Frontiers in behavioral neuroscience 2019;13:239
Calsyntenin-1 Negatively Regulates ICAM5 Accumulation in Postsynaptic Membrane and Influences Dendritic Spine Maturation in a Mouse Model of Fragile X Syndrome.
Cheng K, Chen YS, Yue CX, Zhang SM, Pei YP, Cheng GR, Liu D, Xu L, Dong HX, Zeng Y
Frontiers in neuroscience 2019;13:1098
Frontiers in neuroscience 2019;13:1098
Osteoprotegerin promotes islet β cell proliferation in intrauterine growth retardation rats through the PI3K/AKT/FoxO1 pathway.
Tang S, Xin Y, Yang M, Zhang D, Xu C
International journal of clinical and experimental pathology 2019;12(6):2324-2338
International journal of clinical and experimental pathology 2019;12(6):2324-2338
CD147 promotes cervical cancer migration and invasion by up-regulating fatty acid synthase expression.
Guo W, Abudumijiti H, Xu L, Hasim A
International journal of clinical and experimental pathology 2019;12(12):4280-4288
International journal of clinical and experimental pathology 2019;12(12):4280-4288
CLK3 Is A Direct Target Of miR-144 And Contributes To Aggressive Progression In Hepatocellular Carcinoma.
Li H, Cui X, Hu Q, Chen X, Zhou P
OncoTargets and therapy 2019;12:9201-9213
OncoTargets and therapy 2019;12:9201-9213
Downregulation of CENPK suppresses hepatocellular carcinoma malignant progression through regulating YAP1.
Wang J, Li H, Xia C, Yang X, Dai B, Tao K, Dou K
OncoTargets and therapy 2019;12:869-882
OncoTargets and therapy 2019;12:869-882
INPP4B As A Prognostic And Diagnostic Marker Regulates Cell Growth Of Pancreatic Cancer Via Activating AKT.
Zhai S, Liu Y, Lu X, Qian H, Tang X, Cheng X, Wang Y, Shi Y, Deng X
OncoTargets and therapy 2019;12:8287-8299
OncoTargets and therapy 2019;12:8287-8299
GADD45a Mediated Cell Cycle Inhibition Is Regulated By P53 In Bladder Cancer.
Han N, Yuan F, Xian P, Liu N, Liu J, Zhang H, Zhang H, Yao K, Yuan G
OncoTargets and therapy 2019;12:7591-7599
OncoTargets and therapy 2019;12:7591-7599
MicroRNA-217 acts as a tumor suppressor and correlates with the chemoresistance of cervical carcinoma to cisplatin.
Yin Z, Ren W
OncoTargets and therapy 2019;12:759-771
OncoTargets and therapy 2019;12:759-771
GJB4 promotes gastric cancer cell proliferation and migration via Wnt/CTNNB1 pathway.
Liu G, Pang Y, Zhang Y, Fu H, Xiong W, Zhang Y
OncoTargets and therapy 2019;12:6745-6755
OncoTargets and therapy 2019;12:6745-6755
GPX2 suppression of H(2)O(2) stress regulates cervical cancer metastasis and apoptosis via activation of the β-catenin-WNT pathway.
Wang Y, Cao P, Alshwmi M, Jiang N, Xiao Z, Jiang F, Gu J, Wang X, Sun X, Li S
OncoTargets and therapy 2019;12:6639-6651
OncoTargets and therapy 2019;12:6639-6651
tRNA-derived fragment tRF-03357 promotes cell proliferation, migration and invasion in high-grade serous ovarian cancer.
Zhang M, Li F, Wang J, He W, Li Y, Li H, Wei Z, Cao Y
OncoTargets and therapy 2019;12:6371-6383
OncoTargets and therapy 2019;12:6371-6383
14-Deoxycoleon U-induced endoplasmic reticulum stress-mediated apoptosis, autophagy, and cell cycle arrest in lung adenocarcinoma.
Peng X, Tu Y, Fu S, Xia Y, Ma C, Yang Y, Wu H, Liu Y, You P
OncoTargets and therapy 2019;12:5955-5965
OncoTargets and therapy 2019;12:5955-5965
Diallyl disulfide inhibits colon cancer metastasis by suppressing Rac1-mediated epithelial-mesenchymal transition.
Xia L, Lin J, Su J, Oyang L, Wang H, Tan S, Tang Y, Chen X, Liu W, Luo X, Tian Y, Liang J, Su Q, Liao Q, Zhou Y
OncoTargets and therapy 2019;12:5713-5728
OncoTargets and therapy 2019;12:5713-5728
LncRNA FENDRR attenuates colon cancer progression by repression of SOX4 protein.
Liu J, Du W
OncoTargets and therapy 2019;12:4287-4295
OncoTargets and therapy 2019;12:4287-4295
Exosomal Tenascin-c induces proliferation and invasion of pancreatic cancer cells by WNT signaling.
Qian S, Tan X, Liu X, Liu P, Wu Y
OncoTargets and therapy 2019;12:3197-3205
OncoTargets and therapy 2019;12:3197-3205
Silencing UBE4B induces nasopharyngeal carcinoma apoptosis through the activation of caspase3 and p53.
Weng C, Chen Y, Wu Y, Liu X, Mao H, Fang X, Li B, Wang L, Guan M, Liu G, Lu L, Yuan Y
OncoTargets and therapy 2019;12:2553-2561
OncoTargets and therapy 2019;12:2553-2561
AdipoRon Alleviates Free Fatty Acid-Induced Myocardial Cell Injury Via Suppressing Nlrp3 Inflammasome Activation.
Zhang YZ, Zhang YL, Huang Q, Huang C, Jiang ZL, Cai F, Shen JF
Diabetes, metabolic syndrome and obesity : targets and therapy 2019;12:2165-2179
Diabetes, metabolic syndrome and obesity : targets and therapy 2019;12:2165-2179
RRAD suppresses the Warburg effect by downregulating ACTG1 in hepatocellular carcinoma.
Yan Y, Xu H, Zhang L, Zhou X, Qian X, Zhou J, Huang Y, Ge W, Wang W
OncoTargets and therapy 2019;12:1691-1703
OncoTargets and therapy 2019;12:1691-1703
Upregulation of STC2 in colorectal cancer and its clinicopathological significance.
Zhang C, Chen S, Ma X, Yang Q, Su F, Shu X, Xie W, Feng M, Xiong B
OncoTargets and therapy 2019;12:1249-1258
OncoTargets and therapy 2019;12:1249-1258
Oncogenic Role and Prognostic Value of MicroRNA-937-3p in Patients with Breast Cancer.
Li D, Zhong J, Zhang G, Lin L, Liu Z
OncoTargets and therapy 2019;12:11045-11056
OncoTargets and therapy 2019;12:11045-11056
Osteoglycin (OGN) Inhibits Cell Proliferation and Invasiveness in Breast Cancer via PI3K/Akt/mTOR Signaling Pathway.
Xu T, Zhang R, Dong M, Zhang Z, Li H, Zhan C, Li X
OncoTargets and therapy 2019;12:10639-10650
OncoTargets and therapy 2019;12:10639-10650
Overexpressing CCT6A Contributes To Cancer Cell Growth By Affecting The G1-To-S Phase Transition And Predicts A Negative Prognosis In Hepatocellular Carcinoma.
Zeng G, Wang J, Huang Y, Lian Y, Chen D, Wei H, Lin C, Huang Y
OncoTargets and therapy 2019;12:10427-10439
OncoTargets and therapy 2019;12:10427-10439
miR-140-3p Suppresses Cell Growth And Induces Apoptosis In Colorectal Cancer By Targeting PD-L1.
Jiang W, Li T, Wang J, Jiao R, Shi X, Huang X, Ji G
OncoTargets and therapy 2019;12:10275-10285
OncoTargets and therapy 2019;12:10275-10285
Osteopontin Mediates Cetuximab Resistance via the MAPK Pathway in NSCLC Cells.
Cui J, Wang J, Lin C, Liu J, Zuo W
OncoTargets and therapy 2019;12:10177-10185
OncoTargets and therapy 2019;12:10177-10185
Long noncoding RNA CASC15 predicts unfavorable prognosis and exerts oncogenic functions in non-small cell lung cancer.
Li M, Chen Y, Zhu J, Gao Z, Wang T, Zhou P
American journal of translational research 2019;11(7):4303-4314
American journal of translational research 2019;11(7):4303-4314
MiR-27a-regulated FOXO1 promotes pancreatic ductal adenocarcinoma cell progression by enhancing Wnt/β-catenin signaling activity.
Ling J, Dong X, Wang L, Xue Y, Jia X, Song W, Li Q
American journal of translational research 2019;11(5):3069-3080
American journal of translational research 2019;11(5):3069-3080
Low-molecular-weight fucoidan attenuates bleomycin-induced pulmonary fibrosis: possible role in inhibiting TGF-β1-induced epithelial-mesenchymal transition through ERK pathway.
Wang L, Zhang P, Li X, Zhang Y, Zhan Q, Wang C
American journal of translational research 2019;11(4):2590-2602
American journal of translational research 2019;11(4):2590-2602
Vitamin D retards intervertebral disc degeneration through inactivation of the NF-κB pathway in mice.
Huang H, Cheng S, Zheng T, Ye Y, Ye A, Zhu S, Lin X
American journal of translational research 2019;11(4):2496-2506
American journal of translational research 2019;11(4):2496-2506
Herbacetin treatment remitted LPS induced inhibition of osteoblast differentiation through blocking AKT/NF-κB signaling pathway.
Cai P, Cai T, Li X, Fan L, Chen G, Yu B, Liu T
American journal of translational research 2019;11(2):865-874
American journal of translational research 2019;11(2):865-874
BPTF cooperates with p50 NF-κB to promote COX-2 expression and tumor cell growth in lung cancer.
Dai M, Hu S, Liu CF, Jiang L, Yu W, Li ZL, Guo W, Tang R, Dong CY, Wu TH, Deng WG
American journal of translational research 2019;11(12):7398-7409
American journal of translational research 2019;11(12):7398-7409
Protective effects of Ulinastatin on oxidative stress and inflammation of rat-derived cardiomyocytes H9c2.
Xie X, Li T, Yuan H
American journal of translational research 2019;11(11):7094-7103
American journal of translational research 2019;11(11):7094-7103
A pilot study comparing the genetic molecular biology of gestational and non-gestational choriocarcinoma.
Lazare C, Zhi W, Dai J, Cao C, Sookha RR, Wang L, Meng Y, Gao P, Wu P, Wei J, Hu J, Wu P
American journal of translational research 2019;11(11):7049-7062
American journal of translational research 2019;11(11):7049-7062
HnRNP-F promotes cell proliferation by regulating TPX2 in bladder cancer.
Li F, Su M, Zhao H, Xie W, Cao S, Xu Y, Chen W, Wang L, Hou L, Tan W
American journal of translational research 2019;11(11):7035-7048
American journal of translational research 2019;11(11):7035-7048
UBE2T promotes proliferation via G2/M checkpoint in hepatocellular carcinoma.
Liu LL, Zhu JM, Yu XN, Zhu HR, Shi X, Bilegsaikhan E, Guo HY, Wu J, Shen XZ
Cancer management and research 2019;11:8359-8370
Cancer management and research 2019;11:8359-8370
Overexpression of HOXC6 promotes cell proliferation and migration via MAPK signaling and predicts a poor prognosis in glioblastoma.
Yang P, Kang W, Pan Y, Zhao X, Duan L
Cancer management and research 2019;11:8167-8179
Cancer management and research 2019;11:8167-8179
Upregulation of family with sequence similarity 83 member D expression enhances cell proliferation and motility via activation of Wnt/β-catenin signaling and predicts poor prognosis in gastric cancer.
Wang F, Zhang S, Wei Y, Chen H, Jiao Z, Li Y
Cancer management and research 2019;11:6775-6791
Cancer management and research 2019;11:6775-6791
The β-galactoside α2,6-sialyltranferase 1 (ST6GAL1) inhibits the colorectal cancer metastasis by stabilizing intercellular adhesion molecule-1 via sialylation.
Zhou L, Zhang S, Zou X, Lu J, Yang X, Xu Z, Shan A, Jia W, Liu F, Yan X, Su H, Liang T, Zheng M, Zhang Y, Feng B
Cancer management and research 2019;11:6185-6199
Cancer management and research 2019;11:6185-6199
siPRDX2-elevated DNM3 inhibits the proliferation and metastasis of colon cancer cells via AKT signaling pathway.
Ma Y, Guan L, Han Y, Zhou Y, Li X, Liu Y, Zhang X, Zhang W, Li X, Wang S, Lu W
Cancer management and research 2019;11:5799-5811
Cancer management and research 2019;11:5799-5811
Candidate tumor suppressor gene IRF6 is involved in human breast cancer pathogenesis via modulating PI3K-regulatory subunit PIK3R2 expression.
Xu HF, Huang TJ, Yang Q, Xu L, Lin F, Lang YH, Hu H, Peng LX, Meng DF, Xie YJ, Tan L, Qian CN, Huang BJ
Cancer management and research 2019;11:5557-5572
Cancer management and research 2019;11:5557-5572
Dl-3-n-Butylphthalide Exerts Dopaminergic Neuroprotection Through Inhibition of Neuroinflammation.
Chen Y, Wu T, Li H, Li X, Li Q, Zhu X, Yu M, Kuo SH, Huang F, Wu YC
Frontiers in aging neuroscience 2019;11:44
Frontiers in aging neuroscience 2019;11:44
UNBS5162 and amonafide inhibits tumor progression in human melanoma by the AKT/mTOR pathway.
Ye Y, Huang S, Wu Y
Cancer management and research 2019;11:2339-2348
Cancer management and research 2019;11:2339-2348
The oncogenic role of GNL3 in the progression and metastasis of osteosarcoma.
Li T, Li L, Wu X, Tian K, Wang Y
Cancer management and research 2019;11:2179-2188
Cancer management and research 2019;11:2179-2188
Peptide V3 Inhibits the Growth of Human Hepatocellular Carcinoma by Inhibiting the Ras/Raf/MEK/ERK Signaling Pathway.
Wu D, Li M, Gao Y, Tian W, Li J, Zhang Q, Liu Z, Zheng M, Wang H, Wang J, Teng T, Zhang L, Ji X, Xie Z, Ji A, Li Y
Journal of Cancer 2019;10(7):1693-1706
Journal of Cancer 2019;10(7):1693-1706
Lyn Kinase Promotes the Proliferation of Malignant Melanoma Cells through Inhibition of Apoptosis and Autophagy via the PI3K/Akt Signaling Pathway.
Zhang Q, Meng X, Qin G, Xue X, Dang N
Journal of Cancer 2019;10(5):1197-1208
Journal of Cancer 2019;10(5):1197-1208
High expression of calreticulin indicates poor prognosis and modulates cell migration and invasion via activating Stat3 in nasopharyngeal carcinoma.
Han Y, Liao Q, Wang H, Rao S, Yi P, Tang L, Tian Y, Oyang L, Wang H, Shi Y, Zhou Y
Journal of Cancer 2019;10(22):5460-5468
Journal of Cancer 2019;10(22):5460-5468
The Role of the Tumor Microenvironment in Neuropilin 1-Induced Radiation Resistance in Lung Cancer Cells.
Dong Z, Zhang H, Gong X, Wei W, Lv Y, Chen Z, Wang R, Yi J, Shen Y, Jin S
Journal of Cancer 2019;10(17):4017-4030
Journal of Cancer 2019;10(17):4017-4030
KIAA0101 is a novel transcriptional target of FoxM1 and is involved in the regulation of hepatocellular carcinoma microvascular invasion by regulating epithelial-mesenchymal transition.
Zhang T, Guo J, Gu J, Chen K, Wang Z, Li H, Wang G, Wang J
Journal of Cancer 2019;10(15):3501-3516
Journal of Cancer 2019;10(15):3501-3516
Association of SMUG1 SNPs in Intron Region and Linkage Disequilibrium with Occurrence of Cervical Carcinoma and HPV Infection in Chinese Population.
Ye F, Wang H, Liu J, Cheng Q, Chen X, Chen H
Journal of Cancer 2019;10(1):238-248
Journal of Cancer 2019;10(1):238-248
PINK1/Parkin-Mediated Mitophagy Regulation by Reactive Oxygen Species Alleviates Rocaglamide A-Induced Apoptosis in Pancreatic Cancer Cells.
Zhao C, He R, Shen M, Zhu F, Wang M, Liu Y, Chen H, Li X, Qin R
Frontiers in pharmacology 2019;10:968
Frontiers in pharmacology 2019;10:968
MicroRNA-532-3p Suppresses Malignant Behaviors of Tongue Squamous Cell Carcinoma via Regulating CCR7.
Feng C, So HI, Yin S, Su X, Xu Q, Wang S, Duan W, Zhang E, Sun C, Xu Z
Frontiers in pharmacology 2019;10:940
Frontiers in pharmacology 2019;10:940
ANLN and KDR Are Jointly Prognostic of Breast Cancer Survival and Can Be Modulated for Triple Negative Breast Cancer Control.
Dai X, Mei Y, Chen X, Cai D
Frontiers in genetics 2019;10:790
Frontiers in genetics 2019;10:790
FKN Facilitates HK-2 Cell EMT and Tubulointerstitial Lesions via the Wnt/β-Catenin Pathway in a Murine Model of Lupus Nephritis.
Fu D, Senouthai S, Wang J, You Y
Frontiers in immunology 2019;10:784
Frontiers in immunology 2019;10:784
Emodin Induced SREBP1-Dependent and SREBP1-Independent Apoptosis in Hepatocellular Carcinoma Cells.
Yang N, Li C, Li H, Liu M, Cai X, Cao F, Feng Y, Li M, Wang X
Frontiers in pharmacology 2019;10:709
Frontiers in pharmacology 2019;10:709
Myricetin Attenuated Diabetes-Associated Kidney Injuries and Dysfunction via Regulating Nuclear Factor (Erythroid Derived 2)-Like 2 and Nuclear Factor-κB Signaling.
Yang ZJ, Wang HR, Wang YI, Zhai ZH, Wang LW, Li L, Zhang C, Tang L
Frontiers in pharmacology 2019;10:647
Frontiers in pharmacology 2019;10:647
A Novel α-Galactosidase A Splicing Mutation Predisposes to Fabry Disease.
Li P, Zhang L, Zhao N, Xiong Q, Zhou YA, Wu C, Xiao H
Frontiers in genetics 2019;10:60
Frontiers in genetics 2019;10:60
Sex Dependent Dysregulation of Hepatic Glucose Production in Lean Type 2 Diabetic Rats.
Blesson CS, Schutt A, Chacko S, Marini JC, Mathew PR, Tanchico D, Balakrishnan M, Yallampalli C
Frontiers in endocrinology 2019;10:538
Frontiers in endocrinology 2019;10:538
DNA Sensor IFI204 Contributes to Host Defense Against Staphylococcus aureus Infection in Mice.
Chen W, Yu SX, Zhou FH, Zhang XJ, Gao WY, Li KY, Liu ZZ, Han WY, Yang YJ
Frontiers in immunology 2019;10:474
Frontiers in immunology 2019;10:474
Mechanosensitive Ion Channel Piezo1 Regulates Diet-Induced Adipose Inflammation and Systemic Insulin Resistance.
Zhao C, Sun Q, Tang L, Cao Y, Nourse JL, Pathak MM, Lu X, Yang Q
Frontiers in endocrinology 2019;10:373
Frontiers in endocrinology 2019;10:373
Phosphorylation of Microtubule- Associated Protein 4 Promotes Hypoxic Endothelial Cell Migration and Proliferation.
Zhang J, Li L, Zhang Q, Yang X, Zhang C, Zhang X, Zhang D, Lv Y, Song H, Chen B, Liu Y, Hu J, Huang Y
Frontiers in pharmacology 2019;10:368
Frontiers in pharmacology 2019;10:368
Transient Inhibition of mTORC1 Signaling Ameliorates Irradiation-Induced Liver Damage.
Yang W, Shao L, Zhu S, Li H, Zhang X, Ding C, Wu X, Xu R, Yue M, Tang J, Kuang B, Fan G, Zhu Q, Zeng H
Frontiers in physiology 2019;10:228
Frontiers in physiology 2019;10:228
DDX23, an Evolutionary Conserved dsRNA Sensor, Participates in Innate Antiviral Responses by Pairing With TRIF or MAVS.
Ruan J, Cao Y, Ling T, Li P, Wu S, Peng D, Wang Y, Jia X, Chen S, Xu A, Yuan S
Frontiers in immunology 2019;10:2202
Frontiers in immunology 2019;10:2202
Structural and Functional Characterization of Hermetia illucens Larval Midgut.
Bonelli M, Bruno D, Caccia S, Sgambetterra G, Cappellozza S, Jucker C, Tettamanti G, Casartelli M
Frontiers in physiology 2019;10:204
Frontiers in physiology 2019;10:204
Antiproliferative and Immunoregulatory Effects of Azelaic Acid Against Acute Myeloid Leukemia via the Activation of Notch Signaling Pathway.
Dongdong Z, Jin Y, Yang T, Yang Q, Wu B, Chen Y, Luo Z, Liang L, Liu Y, Xu A, Tong X, Can C, Ding L, Tu H, Tan Y, Jiang H, Liu X, Shen H, Liu L, Pan Y, Wei Y, Zhou F
Frontiers in pharmacology 2019;10:1396
Frontiers in pharmacology 2019;10:1396
Huang-Lian-Jie-Du Decoction Ameliorates Acute Ulcerative Colitis in Mice via Regulating NF-κB and Nrf2 Signaling Pathways and Enhancing Intestinal Barrier Function.
Yuan Z, Yang L, Zhang X, Ji P, Hua Y, Wei Y
Frontiers in pharmacology 2019;10:1354
Frontiers in pharmacology 2019;10:1354
Muscle-Specific Sensitivity to Voluntary Physical Activity and Detraining.
Hyatt JK, Brown EA, Deacon HM, McCall GE
Frontiers in physiology 2019;10:1328
Frontiers in physiology 2019;10:1328
USP37 Promotes Lung Cancer Cell Migration by Stabilizing Snail Protein via Deubiquitination.
Cai J, Li M, Wang X, Li L, Li Q, Hou Z, Jia H, Liu S
Frontiers in genetics 2019;10:1324
Frontiers in genetics 2019;10:1324
Seneca Valley Virus 2C and 3C(pro) Induce Apoptosis via Mitochondrion-Mediated Intrinsic Pathway.
Liu T, Li X, Wu M, Qin L, Chen H, Qian P
Frontiers in microbiology 2019;10:1202
Frontiers in microbiology 2019;10:1202
Parental Renovascular Hypertension-Induced Autonomic Dysfunction in Male Offspring Is Improved by Prenatal or Postnatal Treatment With Hydrogen Sulfide.
Guo Q, Feng X, Xue H, Jin S, Teng X, Duan X, Xiao L, Wu Y
Frontiers in physiology 2019;10:1184
Frontiers in physiology 2019;10:1184
Severe Fever With Thrombocytopenia Syndrome Virus-Induced Macrophage Differentiation Is Regulated by miR-146.
Zhang L, Fu Y, Wang H, Guan Y, Zhu W, Guo M, Zheng N, Wu Z
Frontiers in immunology 2019;10:1095
Frontiers in immunology 2019;10:1095
The Therapeutic Effects of Treadmill Exercise on Osteoarthritis in Rats by Inhibiting the HDAC3/NF-KappaB Pathway in vivo and in vitro.
Zhang H, Ji L, Yang Y, Wei Y, Zhang X, Gang Y, Lu J, Bai L
Frontiers in physiology 2019;10:1060
Frontiers in physiology 2019;10:1060
Protective Effects of Dioscin Against Doxorubicin-Induced Hepatotoxicity Via Regulation of Sirt1/FOXO1/NF-κb Signal.
Song S, Chu L, Liang H, Chen J, Liang J, Huang Z, Zhang B, Chen X
Frontiers in pharmacology 2019;10:1030
Frontiers in pharmacology 2019;10:1030
Apigenin Inhibits IL-6 Transcription and Suppresses Esophageal Carcinogenesis.
Qiu JG, Wang L, Liu WJ, Wang JF, Zhao EJ, Zhou FM, Ji XB, Wang LH, Xia ZK, Wang W, Lin MC, Liu LZ, Huang YX, Jiang BH
Frontiers in pharmacology 2019;10:1002
Frontiers in pharmacology 2019;10:1002
Decreased NDRG1 expression is associated with pregnancy loss in mice and attenuates the in vitro decidualization of endometrial stromal cells.
Meng N, Yang Q, He Y, Gu WW, Gu Y, Zhen XX, Wang J, Zhang X, Sun ZG, Wang J
Molecular reproduction and development 2019 Sep;86(9):1210-1223
Molecular reproduction and development 2019 Sep;86(9):1210-1223
Knockdown of SP1/Syncytin1 axis inhibits the proliferation and metastasis through the AKT and ERK1/2 signaling pathways in non-small cell lung cancer.
Li X, Fu Y, Xia X, Zhang X, Xiao K, Zhuang X, Zhang Y
Cancer medicine 2019 Sep;8(12):5750-5759
Cancer medicine 2019 Sep;8(12):5750-5759
HOXA10 induces BCL2 expression, inhibits apoptosis, and promotes cell proliferation in gastric cancer.
Song C, Han Y, Luo H, Qin Z, Chen Z, Liu Y, Lu S, Sun H, Zhou C
Cancer medicine 2019 Sep;8(12):5651-5661
Cancer medicine 2019 Sep;8(12):5651-5661
Telbivudine antagonizes TLR4 to inhibit the epithelial-to-mesenchymal transition in human proximal tubular epithelial cells in vitro.
Chen J, Li D, Luo E
International immunopharmacology 2019 Sep;74:105683
International immunopharmacology 2019 Sep;74:105683
Functional evaluation of a novel GLA causative mutation in Fabry disease.
Li P, Zhang L, Xiong Q, Wang Z, Cui X, Zhou YA, Wang Y, Xiao H, Wu C
Molecular genetics & genomic medicine 2019 Sep;7(9):e864
Molecular genetics & genomic medicine 2019 Sep;7(9):e864
Cholesterol transport through the peroxisome-ER membrane contacts tethered by PI(4,5)P(2) and extended synaptotagmins.
Xiao J, Luo J, Hu A, Xiao T, Li M, Kong Z, Jiang L, Zhou Z, Liao Y, Xie C, Chu B, Miao H, Li B, Shi X, Song BL
Science China. Life sciences 2019 Sep;62(9):1117-1135
Science China. Life sciences 2019 Sep;62(9):1117-1135
The interaction between PLEKHG2 and ABL1 suppresses cell growth via the NF-κB signaling pathway in HEK293 cells.
Nishikawa M, Nakano S, Nakao H, Sato K, Sugiyama T, Akao Y, Nagaoka H, Yamakawa H, Nagase T, Ueda H
Cellular signalling 2019 Sep;61:93-107
Cellular signalling 2019 Sep;61:93-107
Seneca Valley virus 2C and 3C inhibit type I interferon production by inducing the degradation of RIG-I.
Wen W, Yin M, Zhang H, Liu T, Chen H, Qian P, Hu J, Li X
Virology 2019 Sep;535:122-129
Virology 2019 Sep;535:122-129
Overexpression of matrix metalloproteinase-9 in breast cancer cell lines remarkably increases the cell malignancy largely via activation of transforming growth factor beta/SMAD signalling.
Dong H, Diao H, Zhao Y, Xu H, Pei S, Gao J, Wang J, Hussain T, Zhao D, Zhou X, Lin D
Cell proliferation 2019 Sep;52(5):e12633
Cell proliferation 2019 Sep;52(5):e12633
Essential role of IκB(NS) for in vivo CD4(+) T-cell activation, proliferation, and Th1-cell differentiation during Listeria monocytogenes infection in mice.
Frentzel S, Katsoulis-Dimitriou K, Jeron A, Schmitz I, Bruder D
European journal of immunology 2019 Sep;49(9):1391-1398
European journal of immunology 2019 Sep;49(9):1391-1398
Transforming growth factor β1 promotes fibroblast-like synoviocytes migration and invasion via TGF-β1/Smad signaling in rheumatoid arthritis.
Zhu D, Zhao J, Lou A, Huang Q, OuYang Q, Zhu J, Fan M, He Y, Ren H, Yang M
Molecular and cellular biochemistry 2019 Sep;459(1-2):141-150
Molecular and cellular biochemistry 2019 Sep;459(1-2):141-150
MiR-212-3p inhibits cell proliferation and promotes apoptosis by targeting nuclear factor IA in bladder cancer.
Wu X, Chen H, Zhang G, Wu J, Zhu W, Gu Y, He YI
Journal of biosciences 2019 Sep;44(4)
Journal of biosciences 2019 Sep;44(4)
Hypoxia‑induced mitochondrial translocation of DNM1L increases mitochondrial fission and triggers mPTP opening in HCC cells via activation of HK2.
Cai M, He P, Fang DL
Oncology reports 2019 Sep;42(3):1125-1132
Oncology reports 2019 Sep;42(3):1125-1132
Ubiquitin ligase TRIM65 promotes colorectal cancer metastasis by targeting ARHGAP35 for protein degradation.
Chen D, Li Y, Zhang X, Wu H, Wang Q, Cai J, Cui Y, Liu H, Lan P, Wang J, Yang Z, Wang L
Oncogene 2019 Sep;38(37):6429-6444
Oncogene 2019 Sep;38(37):6429-6444
Downregulation of WW domain-containing oxidoreductase leads to tamoxifen-resistance by the inactivation of Hippo signaling.
Li J, Feng X, Li C, Liu J, Li P, Wang R, Chen H, Liu P
Experimental biology and medicine (Maywood, N.J.) 2019 Sep;244(12):972-982
Experimental biology and medicine (Maywood, N.J.) 2019 Sep;244(12):972-982
NLRC3 inhibits MCT-induced pulmonary hypertension in rats via attenuating PI3K activation.
Zha LH, Zhou J, Li TZ, Luo H, Zhang MQ, Li S, Yu ZX
Journal of cellular physiology 2019 Sep;234(9):15963-15976
Journal of cellular physiology 2019 Sep;234(9):15963-15976
Regional Ischemic Preconditioning Has Clinical Value in Cirrhotic HCC Through MAPK Pathways.
Wang L, Feng L, Rong W, Liu M, Wu F, Yu W, An S, Zhou X, Wu J
Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract 2019 Sep;23(9):1767-1777
Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract 2019 Sep;23(9):1767-1777
Bavachinin exhibits antitumor activity against non‑small cell lung cancer by targeting PPARγ.
Ge LN, Yan L, Li C, Cheng K
Molecular medicine reports 2019 Sep;20(3):2805-2811
Molecular medicine reports 2019 Sep;20(3):2805-2811
Upregulation of EPS8L3 is associated with tumorigenesis and poor prognosis in patients with liver cancer.
Li P, Hu T, Wang H, Tang Y, Ma Y, Wang X, Xu Y, Chen G
Molecular medicine reports 2019 Sep;20(3):2493-2499
Molecular medicine reports 2019 Sep;20(3):2493-2499
Cancer associated fibroblasts are distinguishable from peri-tumor fibroblasts by biological characteristics in TSCC.
Ba P, Zhang X, Yu M, Li L, Duan X, Wang M, Lv S, Fu G, Yang P, Yang C, Sun Q
Oncology letters 2019 Sep;18(3):2484-2490
Oncology letters 2019 Sep;18(3):2484-2490
Probiotic effect on Helicobacter pylori attachment and inhibition of inflammation in human gastric epithelial cells.
Song H, Zhou L, Liu D, Ge L, Li Y
Experimental and therapeutic medicine 2019 Sep;18(3):1551-1562
Experimental and therapeutic medicine 2019 Sep;18(3):1551-1562
Inhibition of polycomb repressor complex 2 ameliorates neointimal hyperplasia by suppressing trimethylation of H3K27 in vascular smooth muscle cells.
Liang J, Li Q, Cai W, Zhang X, Yang B, Li X, Jiang S, Tian S, Zhang K, Song H, Ai D, Zhang X, Wang C, Zhu Y
British journal of pharmacology 2019 Sep;176(17):3206-3219
British journal of pharmacology 2019 Sep;176(17):3206-3219
Functional daidzein enhances the anticancer effect of topotecan and reverses BCRP-mediated drug resistance in breast cancer.
Guo J, Wang Q, Zhang Y, Sun W, Zhang S, Li Y, Wang J, Bao Y
Pharmacological research 2019 Sep;147:104387
Pharmacological research 2019 Sep;147:104387
TRAF4 Promotes Fibroblast Proliferation in Keloids by Destabilizing p53 via Interacting with the Deubiquitinase USP10.
Deng CC, Zhu DH, Chen YJ, Huang TY, Peng Y, Liu SY, Lu P, Xue YH, Xu YP, Yang B, Rong Z
The Journal of investigative dermatology 2019 Sep;139(9):1925-1935.e5
The Journal of investigative dermatology 2019 Sep;139(9):1925-1935.e5
SARI attenuates colon inflammation by promoting STAT1 degradation in intestinal epithelial cells.
Dai L, Liu Y, Cheng L, Wang H, Lin Y, Shi G, Dong Z, Li J, Fan P, Wang Q, Su X, Zhang S, Yang Y, Hu X, Huang W, Zhou Z, Yu D, Probert C, Wei Y, Deng H
Mucosal immunology 2019 Sep;12(5):1130-1140
Mucosal immunology 2019 Sep;12(5):1130-1140
In vitro effect of Pannexin 1 channel on the invasion and migration of I-10 testicular cancer cells via ERK1/2 signaling pathway.
Liu H, Yuan M, Yao Y, Wu D, Dong S, Tong X
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Sep;117:109090
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Sep;117:109090
Treatment with andrographolide sulfonate provides additional benefits to imipenem in a mouse model of Klebsiella pneumoniae pneumonia.
Zhang G, Jiang C, Xie N, Xu Y, Liu L, Liu N
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Sep;117:109065
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Sep;117:109065
circMTO1 promotes tumorigenesis and chemoresistance of cervical cancer via regulating miR-6893.
Chen M, Ai G, Zhou J, Mao W, Li H, Guo J
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Sep;117:109064
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Sep;117:109064
Kinesin family member C1 accelerates bladder cancer cell proliferation and induces epithelial-mesenchymal transition via Akt/GSK3β signaling.
Xiao KH, Teng K, Ye YL, Tan L, Chen MK, Liang HT, Feng ZH, Duan JL, Deng MH, Wei WS, Luo JH, Qin ZK, Xie D
Cancer science 2019 Sep;110(9):2822-2833
Cancer science 2019 Sep;110(9):2822-2833
Inhibiting effect of microRNA-187-3p on osteogenic differentiation of osteoblast precursor cells by suppressing cannabinoid receptor type 2.
Xu A, Yang Y, Shao Y, Wu M, Sun Y
Differentiation; research in biological diversity 2019 Sep-Oct;109:9-15
Differentiation; research in biological diversity 2019 Sep-Oct;109:9-15
Angiopoietin-Like Protein 4 (ANGPTL4) Induces Retinal Pigment Epithelial Barrier Breakdown by Activating Signal Transducer and Activator of Transcription 3 (STAT3): Evidence from ARPE-19 Cells Under Hypoxic Condition and Diabetic Rats.
Yang X, Cao J, Du Y, Gong Q, Cheng Y, Su G
Medical science monitor : international medical journal of experimental and clinical research 2019 Sep 8;25:6742-6754
Medical science monitor : international medical journal of experimental and clinical research 2019 Sep 8;25:6742-6754
De novo synthesis of serine and glycine fuels purine nucleotide biosynthesis in human lung cancer tissues.
Fan TWM, Bruntz RC, Yang Y, Song H, Chernyavskaya Y, Deng P, Zhang Y, Shah PP, Beverly LJ, Qi Z, Mahan AL, Higashi RM, Dang CV, Lane AN
The Journal of biological chemistry 2019 Sep 6;294(36):13464-13477
The Journal of biological chemistry 2019 Sep 6;294(36):13464-13477
lncRNA NR_038323 Suppresses Renal Fibrosis in Diabetic Nephropathy by Targeting the miR-324-3p/DUSP1 Axis.
Ge Y, Wang J, Wu D, Zhou Y, Qiu S, Chen J, Zhu X, Xiang X, Li H, Zhang D
Molecular therapy. Nucleic acids 2019 Sep 6;17:741-753
Molecular therapy. Nucleic acids 2019 Sep 6;17:741-753
Myosin II isoforms play distinct roles in adherens junction biogenesis.
Heuzé ML, Sankara Narayana GHN, D'Alessandro J, Cellerin V, Dang T, Williams DS, Van Hest JC, Marcq P, Mège RM, Ladoux B
eLife 2019 Sep 5;8
eLife 2019 Sep 5;8
CD36 inhibits β-catenin/c-myc-mediated glycolysis through ubiquitination of GPC4 to repress colorectal tumorigenesis.
Fang Y, Shen ZY, Zhan YZ, Feng XC, Chen KL, Li YS, Deng HJ, Pan SM, Wu DH, Ding Y
Nature communications 2019 Sep 4;10(1):3981
Nature communications 2019 Sep 4;10(1):3981
MiR-532-3p suppresses colorectal cancer progression by disrupting the ETS1/TGM2 axis-mediated Wnt/β-catenin signaling.
Gu C, Cai J, Xu Z, Zhou S, Ye L, Yan Q, Zhang Y, Fang Y, Liu Y, Tu C, Wang X, He J, Li Q, Han L, Lin X, Li A, Liu S
Cell death & disease 2019 Sep 30;10(10):739
Cell death & disease 2019 Sep 30;10(10):739
Ubiquitin ligase TRIM71 suppresses ovarian tumorigenesis by degrading mutant p53.
Chen Y, Hao Q, Wang J, Li J, Huang C, Zhang Y, Wu X, Lu H, Zhou X
Cell death & disease 2019 Sep 30;10(10):737
Cell death & disease 2019 Sep 30;10(10):737
Inhibition of MCF-7 breast cancer cell proliferation by a synthetic peptide derived from the C-terminal sequence of Orai channel.
Li S, Yao M, Niu C, Liu D, Tang Z, Gu C, Zhao H, Ke J, Wu S, Wang X, Wu F
Biochemical and biophysical research communications 2019 Sep 3;516(4):1066-1072
Biochemical and biophysical research communications 2019 Sep 3;516(4):1066-1072
Ribavirin Induces Polyamine Depletion via Nucleotide Depletion to Limit Virus Replication.
Tate PM, Mastrodomenico V, Mounce BC
Cell reports 2019 Sep 3;28(10):2620-2633.e4
Cell reports 2019 Sep 3;28(10):2620-2633.e4
microRNA arm-imbalance in part from complementary targets mediated decay promotes gastric cancer progression.
Zhang Z, Pi J, Zou D, Wang X, Xu J, Yu S, Zhang T, Li F, Zhang X, Zhao H, Wang F, Wang D, Ma Y, Yu J
Nature communications 2019 Sep 27;10(1):4397
Nature communications 2019 Sep 27;10(1):4397
NRF2-dependent gene expression promotes ciliogenesis and Hedgehog signaling.
Martin-Hurtado A, Martin-Morales R, Robledinos-Antón N, Blanco R, Palacios-Blanco I, Lastres-Becker I, Cuadrado A, Garcia-Gonzalo FR
Scientific reports 2019 Sep 25;9(1):13896
Scientific reports 2019 Sep 25;9(1):13896
Targeting the IL-1β/IL-1Ra pathways for the aggregation of human islet amyloid polypeptide in an ex vivo organ culture system of the intervertebral disc.
Wu X, Liao Z, Wang K, Hua W, Liu X, Song Y, Zhang Y, Yang S, Yang C
Experimental & molecular medicine 2019 Sep 25;51(9):1-16
Experimental & molecular medicine 2019 Sep 25;51(9):1-16
Modulation of M2 macrophage polarization by the crosstalk between Stat6 and Trim24.
Yu T, Gan S, Zhu Q, Dai D, Li N, Wang H, Chen X, Hou D, Wang Y, Pan Q, Xu J, Zhang X, Liu J, Pei S, Peng C, Wu P, Romano S, Mao C, Huang M, Zhu X, Shen K, Qin J, Xiao Y
Nature communications 2019 Sep 25;10(1):4353
Nature communications 2019 Sep 25;10(1):4353
OPA1 overexpression ameliorates mitochondrial cristae remodeling, mitochondrial dysfunction, and neuronal apoptosis in prion diseases.
Wu W, Zhao D, Shah SZA, Zhang X, Lai M, Yang D, Wu X, Guan Z, Li J, Zhao H, Li W, Gao H, Zhou X, Qiao J, Yang L
Cell death & disease 2019 Sep 24;10(10):710
Cell death & disease 2019 Sep 24;10(10):710
Retromer and TBC1D5 maintain late endosomal RAB7 domains to enable amino acid-induced mTORC1 signaling.
Kvainickas A, Nägele H, Qi W, Dokládal L, Jimenez-Orgaz A, Stehl L, Gangurde D, Zhao Q, Hu Z, Dengjel J, De Virgilio C, Baumeister R, Steinberg F
The Journal of cell biology 2019 Sep 2;218(9):3019-3038
The Journal of cell biology 2019 Sep 2;218(9):3019-3038
Recurrent GNAQ mutation encoding T96S in natural killer/T cell lymphoma.
Li Z, Zhang X, Xue W, Zhang Y, Li C, Song Y, Mei M, Lu L, Wang Y, Zhou Z, Jin M, Bian Y, Zhang L, Wang X, Li L, Li X, Fu X, Sun Z, Wu J, Nan F, Chang Y, Yan J, Yu H, Feng X, Wang G, Zhang D, Fu X, Zhang Y, Young KH, Li W, Zhang M
Nature communications 2019 Sep 16;10(1):4209
Nature communications 2019 Sep 16;10(1):4209
Up-regulated cathepsin C induces macrophage M1 polarization through FAK-triggered p38 MAPK/NF-κB pathway.
Alam S, Liu Q, Liu S, Liu Y, Zhang Y, Yang X, Liu G, Fan K, Ma J
Experimental cell research 2019 Sep 15;382(2):111472
Experimental cell research 2019 Sep 15;382(2):111472
Altered bile acid composition and disposition in a mouse model of non-alcoholic steatohepatitis.
Suga T, Yamaguchi H, Ogura J, Shoji S, Maekawa M, Mano N
Toxicology and applied pharmacology 2019 Sep 15;379:114664
Toxicology and applied pharmacology 2019 Sep 15;379:114664
Extensive disruption of protein interactions by genetic variants across the allele frequency spectrum in human populations.
Fragoza R, Das J, Wierbowski SD, Liang J, Tran TN, Liang S, Beltran JF, Rivera-Erick CA, Ye K, Wang TY, Yao L, Mort M, Stenson PD, Cooper DN, Wei X, Keinan A, Schimenti JC, Clark AG, Yu H
Nature communications 2019 Sep 12;10(1):4141
Nature communications 2019 Sep 12;10(1):4141
Near-Infrared Light-Sensitive Nano Neuro-Immune Blocker Capsule Relieves Pain and Enhances the Innate Immune Response for Necrotizing Infection.
Zhao Q, Wang J, Yin C, Zhang P, Zhang J, Shi M, Shen K, Xiao Y, Zhao Y, Yang X, Zhang Y
Nano letters 2019 Sep 11;19(9):5904-5914
Nano letters 2019 Sep 11;19(9):5904-5914
Transforming growth factor (TGF)-β1-induced miR-133a inhibits myofibroblast differentiation and pulmonary fibrosis.
Wei P, Xie Y, Abel PW, Huang Y, Ma Q, Li L, Hao J, Wolff DW, Wei T, Tu Y
Cell death & disease 2019 Sep 11;10(9):670
Cell death & disease 2019 Sep 11;10(9):670
miR-146a attenuates apoptosis and modulates autophagy by targeting TAF9b/P53 pathway in doxorubicin-induced cardiotoxicity.
Pan JA, Tang Y, Yu JY, Zhang H, Zhang JF, Wang CQ, Gu J
Cell death & disease 2019 Sep 11;10(9):668
Cell death & disease 2019 Sep 11;10(9):668
Exosomal transfer of miR-501 confers doxorubicin resistance and tumorigenesis via targeting of BLID in gastric cancer.
Liu X, Lu Y, Xu Y, Hou S, Huang J, Wang B, Zhao J, Xia S, Fan S, Yu X, Du Y, Hou L, Li Z, Ding Z, An S, Huang B, Li L, Tang J, Ju J, Guan H, Song B
Cancer letters 2019 Sep 10;459:122-134
Cancer letters 2019 Sep 10;459:122-134
Inhibitory effect of taspine derivative TAD1822-7 on tumor cell growth and angiogenesis via suppression of EphrinB2 and related signaling pathways.
Liu R, Yu R, Cui Y, Fan M, Wang B, Zhang Y
Acta pharmaceutica (Zagreb, Croatia) 2019 Sep 1;69(3):423-431
Acta pharmaceutica (Zagreb, Croatia) 2019 Sep 1;69(3):423-431
Tributyltin exposure disturbs hepatic glucose metabolism in male mice.
Xu J, Ou K, Chen C, Li B, Guo J, Zuo Z, Wang C
Toxicology 2019 Sep 1;425:152242
Toxicology 2019 Sep 1;425:152242
Chronic administration of diethylnitrosamine to induce hepatocarcinogenesis and to evaluate its synergistic effect with other hepatotoxins in mice.
Fuentes-Hernández S, Alarcón-Sánchez BR, Guerrero-Escalera D, Montes-Aparicio AV, Castro-Gil MP, Idelfonso-García OG, Rosas-Madrigal S, Aparicio-Bautista DI, Pérez-Hernández JL, Reyes-Gordillo K, Lakshman MR, Vásquez-Garzón VR, Baltiérrez-Hoyos R, López-González ML, Sierra-Santoyo A, Villa-Treviño S, Pérez-Carreón JI, Arellanes-Robledo J
Toxicology and applied pharmacology 2019 Sep 1;378:114611
Toxicology and applied pharmacology 2019 Sep 1;378:114611
Characterization of a novel separase-interacting protein and candidate new securin, Eip1p, in the fungal pathogen Candida albicans.
Sparapani S, Bachewich C
Molecular biology of the cell 2019 Sep 1;30(19):2469-2489
Molecular biology of the cell 2019 Sep 1;30(19):2469-2489
The estrogen-regulated lncRNA H19/miR-216a-5p axis alters stromal cell invasion and migration via ACTA2 in endometriosis.
Xu Z, Zhang L, Yu Q, Zhang Y, Yan L, Chen ZJ
Molecular human reproduction 2019 Sep 1;25(9):550-561
Molecular human reproduction 2019 Sep 1;25(9):550-561
Increased miR-214 expression suppresses cell migration and proliferation in Hirschsprung disease by interacting with PLAGL2.
Wu L, Yuan W, Chen J, Zhou Z, Shu Y, Ji J, Liu Z, Tang Q, Zhang X, Shu X
Pediatric research 2019 Oct;86(4):460-470
Pediatric research 2019 Oct;86(4):460-470
Cinobufagin inhibits tumor growth by inducing apoptosis through Notch signaling pathways in human cholangiocarcinoma.
Ren J, Wang S, Jin L, Ma F, Zhou D, Cai Q
Translational cancer research 2019 Oct;8(6):2461-2469
Translational cancer research 2019 Oct;8(6):2461-2469
Knockdown of METTL14 inhibits the growth and invasion of cervical cancer.
Geng F, Fan MJ, Li J, Liang SM, Li CY, Li N
Translational cancer research 2019 Oct;8(6):2307-2315
Translational cancer research 2019 Oct;8(6):2307-2315
Effect of NOP2 knockdown on colon cancer cell proliferation, migration, and invasion.
Bi J, Huang Y, Liu Y
Translational cancer research 2019 Oct;8(6):2274-2283
Translational cancer research 2019 Oct;8(6):2274-2283
Baicalein and baicalin promote antitumor immunity by suppressing PD-L1 expression in hepatocellular carcinoma cells.
Ke M, Zhang Z, Xu B, Zhao S, Ding Y, Wu X, Wu R, Lv Y, Dong J
International immunopharmacology 2019 Oct;75:105824
International immunopharmacology 2019 Oct;75:105824
Potential role of M2 macrophage polarization in ventilator-induced lung fibrosis.
Wang L, Zhang Y, Zhang N, Xia J, Zhan Q, Wang C
International immunopharmacology 2019 Oct;75:105795
International immunopharmacology 2019 Oct;75:105795
MiR-92a regulates endothelial progenitor cells (EPCs) by targeting GDF11 via activate SMAD2/3/FAK/Akt/eNOS pathway.
Huang HT, Liu ZC, Wu KQ, Gu SR, Lu TC, Zhong CJ, Zhou YX
Annals of translational medicine 2019 Oct;7(20):563
Annals of translational medicine 2019 Oct;7(20):563
Direct Amplification of Tissue Factor:Factor VIIa Procoagulant Activity by Bile Acids Drives Intrahepatic Coagulation.
Baker KS, Kopec AK, Pant A, Poole LG, Cline-Fedewa H, Ivkovich D, Olyaee M, Woolbright BL, Miszta A, Jaeschke H, Wolberg AS, Luyendyk JP
Arteriosclerosis, thrombosis, and vascular biology 2019 Oct;39(10):2038-2048
Arteriosclerosis, thrombosis, and vascular biology 2019 Oct;39(10):2038-2048
LINC00346 promotes pancreatic cancer progression through the CTCF-mediated Myc transcription.
Peng WX, He RZ, Zhang Z, Yang L, Mo YY
Oncogene 2019 Oct;38(41):6770-6780
Oncogene 2019 Oct;38(41):6770-6780
HBx regulates transcription factor PAX8 stabilization to promote the progression of hepatocellular carcinoma.
Wang J, Li N, Huang ZB, Fu S, Yu SM, Fu YM, Zhou PC, Chen RC, Zhou RR, Huang Y, Hu XW, Fan XG
Oncogene 2019 Oct;38(40):6696-6710
Oncogene 2019 Oct;38(40):6696-6710
Antioxidant activity of Coridius chinensis extracts on manganese-induced testicular damage in rats.
Liu Q, Cen C, Fu H, Wang F, Wang Y, Xu T, Hou X
Environmental toxicology 2019 Oct;34(10):1067-1073
Environmental toxicology 2019 Oct;34(10):1067-1073
Genistein inhibits nasopharyngeal cancer stem cells through sonic hedgehog signaling.
Zhang Q, Cao WS, Wang XQ, Zhang M, Lu XM, Chen JQ, Chen Y, Ge MM, Zhong CY, Han HY
Phytotherapy research : PTR 2019 Oct;33(10):2783-2791
Phytotherapy research : PTR 2019 Oct;33(10):2783-2791
MiR-100 suppresses inflammatory activation of microglia and neuronal apoptosis following spinal cord injury via TLR4/NF-κB pathway.
Li XH, Fu NS, Xing ZM
European review for medical and pharmacological sciences 2019 Oct;23(20):8713-8720
European review for medical and pharmacological sciences 2019 Oct;23(20):8713-8720
miR-29a promotes pathological cardiac hypertrophy by targeting the PTEN/AKT/mTOR signalling pathway and suppressing autophagy.
Shi JY, Chen C, Xu X, Lu Q
Acta physiologica (Oxford, England) 2019 Oct;227(2):e13323
Acta physiologica (Oxford, England) 2019 Oct;227(2):e13323
Silencing lncRNA SNHG6 suppresses proliferation and invasion of breast cancer cells through miR-26a/VASP axis.
Li K, Ma YB, Tian YH, Xu XL, Gao Y, He YQ, Pan WT, Zhang JW, He CJ, Wei L
Pathology, research and practice 2019 Oct;215(10):152575
Pathology, research and practice 2019 Oct;215(10):152575
NKAP functions as an oncogene in Ewing sarcoma cells partly through the AKT signaling pathway.
Li F, Wu JT, Wang PF, Qu LZ
Experimental and therapeutic medicine 2019 Oct;18(4):3037-3045
Experimental and therapeutic medicine 2019 Oct;18(4):3037-3045
GSK343 induces autophagy and downregulates the AKT/mTOR signaling pathway in pancreatic cancer cells.
Xu H, Zhang L, Qian X, Zhou X, Yan Y, Zhou J, Ge W, Albahde M, Wang W
Experimental and therapeutic medicine 2019 Oct;18(4):2608-2616
Experimental and therapeutic medicine 2019 Oct;18(4):2608-2616
Ginsenoside Rg5 induces G2/M phase arrest, apoptosis and autophagy via regulating ROS-mediated MAPK pathways against human gastric cancer.
Liu Y, Fan D
Biochemical pharmacology 2019 Oct;168:285-304
Biochemical pharmacology 2019 Oct;168:285-304
Hyperoside protects against heart failure-induced liver fibrosis in rats.
Guo X, Zhu C, Liu X, Ge Y, Jiang X, Zhao W
Acta histochemica 2019 Oct;121(7):804-811
Acta histochemica 2019 Oct;121(7):804-811
LXRα-mediated downregulation of EGFR suppress colorectal cancer cell proliferation.
Liang X, Cao Y, Xiang S, Xiang Z
Journal of cellular biochemistry 2019 Oct;120(10):17391-17404
Journal of cellular biochemistry 2019 Oct;120(10):17391-17404
LMX1B involved in the radioresistance, proliferation and migration of esophageal cancer cells.
Zang C, Zhao F, Pu Y
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Oct;118:109358
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Oct;118:109358
Magnesium lithospermate B attenuates renal injury in 5/6 renal ablation/infarction rats by mitochondrial pathway of apoptosis.
Wang M, Yang L, Yang J, Zhou Y, Wang C
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Oct;118:109316
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Oct;118:109316
ACT001, a novel PAI-1 inhibitor, exerts synergistic effects in combination with cisplatin by inhibiting PI3K/AKT pathway in glioma.
Xi X, Liu N, Wang Q, Chu Y, Yin Z, Ding Y, Lu Y
Cell death & disease 2019 Oct 7;10(10):757
Cell death & disease 2019 Oct 7;10(10):757
Strong anion exchange-mediated phosphoproteomics reveals extensive human non-canonical phosphorylation.
Hardman G, Perkins S, Brownridge PJ, Clarke CJ, Byrne DP, Campbell AE, Kalyuzhnyy A, Myall A, Eyers PA, Jones AR, Eyers CE
The EMBO journal 2019 Oct 4;38(21):e100847
The EMBO journal 2019 Oct 4;38(21):e100847
Cichorium intybus L. Extract Suppresses Experimental Gout by Inhibiting the NF-κB and NLRP3 Signaling Pathways.
Wang Y, Lin Z, Zhang B, Jiang Z, Guo F, Yang T
International journal of molecular sciences 2019 Oct 4;20(19)
International journal of molecular sciences 2019 Oct 4;20(19)
Improvement of Mitochondrial Activity and Fibrosis by Resveratrol Treatment in Mice with Schistosoma japonicum Infection.
Chen TT, Peng S, Wang Y, Hu Y, Shen Y, Xu Y, Yin J, Liu C, Cao J
Biomolecules 2019 Oct 25;9(11)
Biomolecules 2019 Oct 25;9(11)
Activated spinal astrocytes contribute to the later phase of carrageenan-induced prostatitis pain.
Deng GC, Lu M, Zhao YY, Yuan Y, Chen G
Journal of neuroinflammation 2019 Oct 25;16(1):189
Journal of neuroinflammation 2019 Oct 25;16(1):189
YTHDF1 links hypoxia adaptation and non-small cell lung cancer progression.
Shi Y, Fan S, Wu M, Zuo Z, Li X, Jiang L, Shen Q, Xu P, Zeng L, Zhou Y, Huang Y, Yang Z, Zhou J, Gao J, Zhou H, Xu S, Ji H, Shi P, Wu DD, Yang C, Chen Y
Nature communications 2019 Oct 25;10(1):4892
Nature communications 2019 Oct 25;10(1):4892
Discovery of Novel Aryl Carboxamide Derivatives as Hypoxia-Inducible Factor 1α Signaling Inhibitors with Potent Activities of Anticancer Metastasis.
Liu M, Liang Y, Zhu Z, Wang J, Cheng X, Cheng J, Xu B, Li R, Liu X, Wang Y
Journal of medicinal chemistry 2019 Oct 24;62(20):9299-9314
Journal of medicinal chemistry 2019 Oct 24;62(20):9299-9314
MicroRNA-29a Suppresses CD36 to Ameliorate High Fat Diet-Induced Steatohepatitis and Liver Fibrosis in Mice.
Lin HY, Wang FS, Yang YL, Huang YH
Cells 2019 Oct 22;8(10)
Cells 2019 Oct 22;8(10)
The protective effect of Phellinus linteus decoction on podocyte injury in the kidney of FSGS rats.
Wan F, Yang RC, Shi YP, Tang YW, Tang XL, Zhu XL, Li YG, Wang YJ
BMC complementary and alternative medicine 2019 Oct 21;19(1):272
BMC complementary and alternative medicine 2019 Oct 21;19(1):272
Systematically characterize the clinical and biological significances of 1p19q genes in 1p/19q non-codeletion glioma.
Chai RC, Zhang KN, Chang YZ, Wu F, Liu YQ, Zhao Z, Wang KY, Chang YH, Jiang T, Wang YZ
Carcinogenesis 2019 Oct 16;40(10):1229-1239
Carcinogenesis 2019 Oct 16;40(10):1229-1239
N(6)-methyladenosine modification of circNSUN2 facilitates cytoplasmic export and stabilizes HMGA2 to promote colorectal liver metastasis.
Chen RX, Chen X, Xia LP, Zhang JX, Pan ZZ, Ma XD, Han K, Chen JW, Judde JG, Deas O, Wang F, Ma NF, Guan X, Yun JP, Wang FW, Xu RH, Dan Xie
Nature communications 2019 Oct 16;10(1):4695
Nature communications 2019 Oct 16;10(1):4695
Exosomal and extracellular HMGB1 have opposite effects on SASH1 expression in rat astrocytes and glioma C6 cells.
Ma C, Chen H, Zhang S, Yan Y, Wu R, Wang Y, Liu Y, Yang L, Liu M
Biochemical and biophysical research communications 2019 Oct 15;518(2):325-330
Biochemical and biophysical research communications 2019 Oct 15;518(2):325-330
Bromodomain-containing protein 4 contributes to renal fibrosis through the induction of epithelial-mesenchymal transition.
Wang X, Zhou Y, Peng Y, Huang T, Xia F, Yang T, Duan Q, Zhang W
Experimental cell research 2019 Oct 15;383(2):111507
Experimental cell research 2019 Oct 15;383(2):111507
Human Umbilical Cord-Derived Mesenchymal Stem Cells Relieve Hind Limb Ischemia by Promoting Angiogenesis in Mice.
Wang Z, Zheng L, Lian C, Qi Y, Li W, Wang S
Stem cells and development 2019 Oct 15;28(20):1384-1397
Stem cells and development 2019 Oct 15;28(20):1384-1397
Dystroglycan is involved in the activation of ERK pathway inducing the change of AQP4 expression in scratch-injured astrocytes.
Zhang G, Ma P, Wan S, Xu J, Yang M, Qiu G, Zhuo F, Xu S, Huo J, Ju Y, Liu H
Brain research 2019 Oct 15;1721:146347
Brain research 2019 Oct 15;1721:146347
Endothelial cell pyroptosis plays an important role in Kawasaki disease via HMGB1/RAGE/cathespin B signaling pathway and NLRP3 inflammasome activation.
Jia C, Zhang J, Chen H, Zhuge Y, Chen H, Qian F, Zhou K, Niu C, Wang F, Qiu H, Wang Z, Xiao J, Rong X, Chu M
Cell death & disease 2019 Oct 14;10(10):778
Cell death & disease 2019 Oct 14;10(10):778
A circular RNA from APC inhibits the proliferation of diffuse large B-cell lymphoma by inactivating Wnt/β-catenin signaling via interacting with TET1 and miR-888.
Hu Y, Zhao Y, Shi C, Ren P, Wei B, Guo Y, Ma J
Aging 2019 Oct 13;11(19):8068-8084
Aging 2019 Oct 13;11(19):8068-8084
Polyphenol-Rich Extracts from Toona sinensis Bark and Fruit Ameliorate Free Fatty Acid-Induced Lipogenesis through AMPK and LC3 Pathways.
Chen YC, Chen HJ, Huang BM, Chen YC, Chang CF
Journal of clinical medicine 2019 Oct 11;8(10)
Journal of clinical medicine 2019 Oct 11;8(10)
TMEM18 inhibits osteogenic differentiation of rat bone marrow-derived mesenchymal stem cells by inactivating β-catenin.
Zhang Y, Wang H, Yin T, Liu Y, Zhou W, Fan X, Wu L, Song C, Shao J, Yang T
Experimental cell research 2019 Oct 1;383(1):111491
Experimental cell research 2019 Oct 1;383(1):111491
Genetic loss of Gas6/Mer pathway attenuates silica-induced lung inflammation and fibrosis in mice.
Li W, Xie L, Ma J, Yang M, Wang B, Xu Y, Fan L, Mu G, Shi T, Chen W
Toxicology letters 2019 Oct 1;313:178-187
Toxicology letters 2019 Oct 1;313:178-187
Serum miR-221-3p as a new potential biomarker for depressed mood in perioperative patients.
Feng J, Wang M, Li M, Yang J, Jia J, Liu L, Zhou J, Zhang C, Wang X
Brain research 2019 Oct 1;1720:146296
Brain research 2019 Oct 1;1720:146296
Prolonged neutrophil retention in the wound impairs zebrafish heart regeneration after cryoinjury.
Xu S, Xie F, Tian L, Manno SH, Manno FAM 3rd, Cheng SH
Fish & shellfish immunology 2019 Nov;94:447-454
Fish & shellfish immunology 2019 Nov;94:447-454
lncRNA ABHD11-AS1, regulated by the EGFR pathway, contributes to the ovarian cancer tumorigenesis by epigenetically suppressing TIMP2.
Zeng XY, Jiang XY, Yong JH, Xie H, Yuan J, Zeng D, Dou YY, Xiao SS
Cancer medicine 2019 Nov;8(16):7074-7085
Cancer medicine 2019 Nov;8(16):7074-7085
Combined MEK inhibition and tumor-associated macrophages depletion suppresses tumor growth in a triple-negative breast cancer mouse model.
Zhang Q, Le K, Xu M, Zhou J, Xiao Y, Yang W, Jiang Y, Xi Z, Huang T
International immunopharmacology 2019 Nov;76:105864
International immunopharmacology 2019 Nov;76:105864
Role of miR-214 in regulation of β-catenin and the malignant phenotype of melanoma.
Prabhakar K, Rodrίguez CI, Jayanthy AS, Mikheil DM, Bhasker AI, Perera RJ, Setaluri V
Molecular carcinogenesis 2019 Nov;58(11):1974-1984
Molecular carcinogenesis 2019 Nov;58(11):1974-1984
Allele-selective lowering of mutant HTT protein by HTT-LC3 linker compounds.
Li Z, Wang C, Wang Z, Zhu C, Li J, Sha T, Ma L, Gao C, Yang Y, Sun Y, Wang J, Sun X, Lu C, Difiglia M, Mei Y, Ding C, Luo S, Dang Y, Ding Y, Fei Y, Lu B
Nature 2019 Nov;575(7781):203-209
Nature 2019 Nov;575(7781):203-209
Structural characterization and biological function of bivalent binding of CD2AP to intrinsically disordered domain of chikungunya virus nsP3 protein.
Agback P, Dominguez F, Pustovalova Y, Lukash T, Shiliaev N, Orekhov VY, Frolov I, Agback T, Frolova EI
Virology 2019 Nov;537:130-142
Virology 2019 Nov;537:130-142
Upregulated PDK4 expression is a sensitive marker of increased fatty acid oxidation.
Pettersen IKN, Tusubira D, Ashrafi H, Dyrstad SE, Hansen L, Liu XZ, Nilsson LIH, Løvsletten NG, Berge K, Wergedahl H, Bjørndal B, Fluge Ø, Bruland O, Rustan AC, Halberg N, Røsland GV, Berge RK, Tronstad KJ
Mitochondrion 2019 Nov;49:97-110
Mitochondrion 2019 Nov;49:97-110
Dehydrogenase/reductase SDR family member 2 silencing sensitizes an oxaliplatin‑resistant cell line to oxaliplatin by inhibiting excision repair cross‑complementing group 1 protein expression.
Li JM, Jiang GM, Zhao L, Yang F, Yuan WQ, Wang H, Luo YQ
Oncology reports 2019 Nov;42(5):1725-1734
Oncology reports 2019 Nov;42(5):1725-1734
KDELR2 Promotes Glioblastoma Tumorigenesis Targeted by HIF1a via mTOR Signaling Pathway.
Liao Z, She C, Ma L, Sun Z, Li P, Zhang X, Wang P, Li W
Cellular and molecular neurobiology 2019 Nov;39(8):1207-1215
Cellular and molecular neurobiology 2019 Nov;39(8):1207-1215
The digestive system of the adult Hermetia illucens (Diptera: Stratiomyidae): morphological features and functional properties.
Bruno D, Bonelli M, Cadamuro AG, Reguzzoni M, Grimaldi A, Casartelli M, Tettamanti G
Cell and tissue research 2019 Nov;378(2):221-238
Cell and tissue research 2019 Nov;378(2):221-238
The protective effect of lithocholic acid on the intestinal epithelial barrier is mediated by the vitamin D receptor via a SIRT1/Nrf2 and NF-κB dependent mechanism in Caco-2 cells.
Yao B, He J, Yin X, Shi Y, Wan J, Tian Z
Toxicology letters 2019 Nov;316:109-118
Toxicology letters 2019 Nov;316:109-118
Transcription factor 7-like 2-associated signaling mechanism in regulating cementum generation by the NF-κB pathway.
Zhao Z, Dai J, Yin C, Wang X, Wang J, Jia X, Zhao Q, Fu H, Zhang Y, Xia H
Journal of cellular physiology 2019 Nov;234(11):20790-20800
Journal of cellular physiology 2019 Nov;234(11):20790-20800
EphA8 acts as an oncogene and contributes to poor prognosis in gastric cancer via regulation of ADAM10.
Wang Y, Zhou N, Li P, Wu H, Wang Q, Gao X, Wang X, Huang J
Journal of cellular physiology 2019 Nov;234(11):20408-20419
Journal of cellular physiology 2019 Nov;234(11):20408-20419
The miR-27a-3p/USP25 axis participates in the pathogenesis of recurrent miscarriage by inhibiting trophoblast migration and invasion.
Ding J, Cheng Y, Zhang Y, Liao S, Yin T, Yang J
Journal of cellular physiology 2019 Nov;234(11):19951-19963
Journal of cellular physiology 2019 Nov;234(11):19951-19963
GSK-3β inhibition protects the rat heart from the lipopolysaccharide-induced inflammation injury via suppressing FOXO3A activity.
Li Z, Zhu H, Liu C, Wang Y, Wang D, Liu H, Cao W, Hu Y, Lin Q, Tong C, Lu M, Sachinidis A, Li L, Peng L
Journal of cellular and molecular medicine 2019 Nov;23(11):7796-7809
Journal of cellular and molecular medicine 2019 Nov;23(11):7796-7809
Long non-coding RNA cardiac hypertrophy-associated regulator governs cardiac hypertrophy via regulating miR-20b and the downstream PTEN/AKT pathway.
Zhang M, Jiang Y, Guo X, Zhang B, Wu J, Sun J, Liang H, Shan H, Zhang Y, Liu J, Wang Y, Wang L, Zhang R, Yang B, Xu C
Journal of cellular and molecular medicine 2019 Nov;23(11):7685-7698
Journal of cellular and molecular medicine 2019 Nov;23(11):7685-7698
TMPO-AS1 promotes cervical cancer progression by upregulating RAB14 via sponging miR-577.
Yang J, Liang B, Hou S
The journal of gene medicine 2019 Nov;21(11):e3125
The journal of gene medicine 2019 Nov;21(11):e3125
Knockdown of long noncoding RNA DLEU1 suppresses the progression of renal cell carcinoma by downregulating the Akt pathway.
Yue G, Chen C, Bai L, Wang G, Huang Y, Wang Y, Cui H, Xiao Y
Molecular medicine reports 2019 Nov;20(5):4551-4557
Molecular medicine reports 2019 Nov;20(5):4551-4557
Deficiency of PTEN leads to aberrant chromosome segregation through downregulation of MAD2.
Sun Z, Lu J, Wu M, Li M, Bai L, Shi Z, Hao L, Wu Y
Molecular medicine reports 2019 Nov;20(5):4235-4243
Molecular medicine reports 2019 Nov;20(5):4235-4243
Downregulation of transgelin 2 promotes breast cancer metastasis by activating the reactive oxygen species/nuclear factor‑κB signaling pathway.
Yang L, Hong Q, Xu SG, Kuang XY, Di GH, Liu GY, Wu J, Shao ZM, Yu SJ
Molecular medicine reports 2019 Nov;20(5):4045-4258
Molecular medicine reports 2019 Nov;20(5):4045-4258
Identification of two novel RHO mutations in Chinese retinitis pigmentosa patients.
Wang J, Xu D, Zhu T, Zhou Y, Chen X, Wang F, Zhang J, Tian H, Gao F, Zhang J, Jin C, Xu J, Lu L, Liu Q, Xu GT
Experimental eye research 2019 Nov;188:107726
Experimental eye research 2019 Nov;188:107726
SNX3 suppresses the migration and invasion of colorectal cancer cells by reversing epithelial-to-mesenchymal transition via the β-catenin pathway.
Pan B, Zhang T, Yang W, Liu Y, Chen Y, Zhou Z, Tang Y, Zeng J, Liu Y, Zhao C, Guo Y
Oncology letters 2019 Nov;18(5):5332-5340
Oncology letters 2019 Nov;18(5):5332-5340
Exogenous hydrogen sulfide protects against high glucose-induced apoptosis and oxidative stress by inhibiting the STAT3/HIF-1α pathway in H9c2 cardiomyocytes.
Li J, Yuan YQ, Zhang L, Zhang H, Zhang SW, Zhang Y, Xuan XX, Wang MJ, Zhang JY
Experimental and therapeutic medicine 2019 Nov;18(5):3948-3958
Experimental and therapeutic medicine 2019 Nov;18(5):3948-3958
C2-lacking isoform of Nedd4-2 regulates excitatory synaptic strength through GluA1 ubiquitination-independent mechanisms.
Zhu J, Lee KY, Jong TT, Tsai NP
Journal of neurochemistry 2019 Nov;151(3):289-300
Journal of neurochemistry 2019 Nov;151(3):289-300
Atsttrin reduces lipopolysaccharide-induced neuroinflammation by inhibiting the nuclear factor kappa B signaling pathway.
Liu L, Qu Y, Liu Y, Zhao H, Ma HC, Noor AF, Ji CJ, Nie L, Si M, Cheng L
Neural regeneration research 2019 Nov;14(11):1994-2002
Neural regeneration research 2019 Nov;14(11):1994-2002
C9orf72 intermediate repeats are associated with corticobasal degeneration, increased C9orf72 expression and disruption of autophagy.
Cali CP, Patino M, Tai YK, Ho WY, McLean CA, Morris CM, Seeley WW, Miller BL, Gaig C, Vonsattel JPG, White CL 3rd, Roeber S, Kretzschmar H, Troncoso JC, Troakes C, Gearing M, Ghetti B, Van Deerlin VM, Lee VM, Trojanowski JQ, Mok KY, Ling H, Dickson DW, Schellenberg GD, Ling SC, Lee EB
Acta neuropathologica 2019 Nov;138(5):795-811
Acta neuropathologica 2019 Nov;138(5):795-811
Delta-aminolevulinic acid synthase 2 expression in combination with iron as modifiers of disease severity in erythropoietic protoporphyria.
Barman-Aksözen J, Halloy F, Iyer PS, Schümperli D, Minder AE, Hall J, Minder EI, Schneider-Yin X
Molecular genetics and metabolism 2019 Nov;128(3):304-308
Molecular genetics and metabolism 2019 Nov;128(3):304-308
Transmural pressure drives proliferation of human arterial smooth muscle cells via mechanism associated with NADPH oxidase and Survivin.
Ran K, Yang Z, Zhao Y, Wang X
Microvascular research 2019 Nov;126:103905
Microvascular research 2019 Nov;126:103905
IL-22 suppresses HSV-2 replication in human cervical epithelial cells.
Xu XQ, Liu Y, Zhang B, Liu H, Shao DD, Liu JB, Wang X, Zhou LN, Hu WH, Ho WZ
Cytokine 2019 Nov;123:154776
Cytokine 2019 Nov;123:154776
miR-9-5p attenuates ischemic stroke through targeting ERMP1-mediated endoplasmic reticulum stress.
Chi L, Jiao D, Nan G, Yuan H, Shen J, Gao Y
Acta histochemica 2019 Nov;121(8):151438
Acta histochemica 2019 Nov;121(8):151438
Serum proteomics analysis based on label-free revealed the protective effect of Chinese herbal formula Gu-Ben-Fang-Xiao.
Xing QQ, Liu LW, Zhao X, Lu Y, Dong YM, Liang ZQ
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Nov;119:109390
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Nov;119:109390
G9a and histone deacetylases are crucial for Snail2-mediated E-cadherin repression and metastasis in hepatocellular carcinoma.
Hu Y, Zheng Y, Dai M, Wang X, Wu J, Yu B, Zhang H, Cui Y, Kong W, Wu H, Yu X
Cancer science 2019 Nov;110(11):3442-3452
Cancer science 2019 Nov;110(11):3442-3452
The metabolic regulator small heterodimer partner contributes to the glucose and lipid homeostasis abnormalities induced by hepatitis C virus infection.
Chen J, Zhou Y, Zhuang Y, Qin T, Guo M, Jiang J, Niu J, Li JZ, Chen X, Wang Q
Metabolism: clinical and experimental 2019 Nov;100:153954
Metabolism: clinical and experimental 2019 Nov;100:153954
Double-stranded RNA deaminase ADAR1 promotes the Zika virus replication by inhibiting the activation of protein kinase PKR.
Zhou S, Yang C, Zhao F, Huang Y, Lin Y, Huang C, Ma X, Du J, Wang Y, Long G, He J, Liu C, Zhang P
The Journal of biological chemistry 2019 Nov 29;294(48):18168-18180
The Journal of biological chemistry 2019 Nov 29;294(48):18168-18180
Microtubule destabilization caused by silicate via HDAC6 activation contributes to autophagic dysfunction in bone mesenchymal stem cells.
Li Z, Liu S, Fu T, Peng Y, Zhang J
Stem cell research & therapy 2019 Nov 27;10(1):351
Stem cell research & therapy 2019 Nov 27;10(1):351
Astaxanthin protects against osteoarthritis via Nrf2: a guardian of cartilage homeostasis.
Sun K, Luo J, Jing X, Guo J, Yao X, Hao X, Ye Y, Liang S, Lin J, Wang G, Guo F
Aging 2019 Nov 26;11(22):10513-10531
Aging 2019 Nov 26;11(22):10513-10531
Long noncoding RNA LINC01111 suppresses pancreatic cancer aggressiveness by regulating DUSP1 expression via microRNA-3924.
Pan S, Shen M, Zhou M, Shi X, He R, Yin T, Wang M, Guo X, Qin R
Cell death & disease 2019 Nov 25;10(12):883
Cell death & disease 2019 Nov 25;10(12):883
ZFP161 regulates replication fork stability and maintenance of genomic stability by recruiting the ATR/ATRIP complex.
Kim W, Zhao F, Wu R, Qin S, Nowsheen S, Huang J, Zhou Q, Chen Y, Deng M, Guo G, Luo K, Lou Z, Yuan J
Nature communications 2019 Nov 22;10(1):5304
Nature communications 2019 Nov 22;10(1):5304
CD105 Is Expressed in Ovarian Cancer Precursor Lesions and Is Required for Metastasis to the Ovary.
Bai S, Zhu W, Coffman L, Vlad A, Schwartz LE, Elishaev E, Drapkin R, Buckanovich RJ
Cancers 2019 Nov 2;11(11)
Cancers 2019 Nov 2;11(11)
Tissue plasminogen activator disrupts the blood-brain barrier through increasing the inflammatory response mediated by pericytes after cerebral ischemia.
Yang E, Cai Y, Yao X, Liu J, Wang Q, Jin W, Wu Q, Fan W, Qiu L, Kang C, Wu J
Aging 2019 Nov 18;11(22):10167-10182
Aging 2019 Nov 18;11(22):10167-10182
Efficient Delivery of Therapeutic siRNA by Fe(3)O(4) Magnetic Nanoparticles into Oral Cancer Cells.
Jin L, Wang Q, Chen J, Wang Z, Xin H, Zhang D
Pharmaceutics 2019 Nov 17;11(11)
Pharmaceutics 2019 Nov 17;11(11)
Chemerin-induced macrophages pyroptosis in fetal brain tissue leads to cognitive disorder in offspring of diabetic dams.
Liang Z, Han L, Sun D, Chen Y, Wu Q, Zhang L, Zhou M, Chen D
Journal of neuroinflammation 2019 Nov 16;16(1):226
Journal of neuroinflammation 2019 Nov 16;16(1):226
Viral Nonstructural Protein 1 Induces Mitochondrion-Mediated Apoptosis in Mink Enteritis Virus Infection.
Lin P, Cheng Y, Song S, Qiu J, Yi L, Cao Z, Li J, Cheng S, Wang J
Journal of virology 2019 Nov 15;93(22)
Journal of virology 2019 Nov 15;93(22)
Nitidine chloride induces S phase cell cycle arrest and mitochondria-dependent apoptosis in HaCaT cells and ameliorates skin lesions in psoriasis-like mouse models.
Yang XG, Jiang BW, Jing QQ, Li WJ, Tan LP, Bao YL, Song ZB, Yu CL, Liu L, Liu YC, Li YX
European journal of pharmacology 2019 Nov 15;863:172680
European journal of pharmacology 2019 Nov 15;863:172680
Aberrant activation of RPB1 is critical for cell overgrowth in acute myeloid leukemia.
Yu Q, Xu Y, Zhuang H, Wu Z, Zhang L, Li J, Yang L, Wu B, Wang P, Zhang X, Gan X, Liang Y, Zheng S, Yu X, Gu Y, Xu R
Experimental cell research 2019 Nov 15;384(2):111653
Experimental cell research 2019 Nov 15;384(2):111653
A thiazole-derived oridonin analogue exhibits antitumor activity by directly and allosterically inhibiting STAT3.
Shen X, Zhao L, Chen P, Gong Y, Liu D, Zhang X, Dai L, Sun Q, Lou J, Jin Z, Zhang B, Niu D, Chen C, Qi X, Jia D
The Journal of biological chemistry 2019 Nov 15;294(46):17471-17486
The Journal of biological chemistry 2019 Nov 15;294(46):17471-17486
FUS-mediated dysregulation of Sema5a, an autism-related gene, in FUS mice with hippocampus-dependent cognitive deficits.
Ho WY, Chang JC, Tyan SH, Yen YC, Lim K, Tan BSY, Ong J, Tucker-Kellogg G, Wong P, Koo E, Ling SC
Human molecular genetics 2019 Nov 15;28(22):3777-3791
Human molecular genetics 2019 Nov 15;28(22):3777-3791
β-Caryophyllene protects against ischemic stroke by promoting polarization of microglia toward M2 phenotype via the TLR4 pathway.
Tian X, Liu H, Xiang F, Xu L, Dong Z
Life sciences 2019 Nov 15;237:116915
Life sciences 2019 Nov 15;237:116915
Covalent Ligand Screening Uncovers a RNF4 E3 Ligase Recruiter for Targeted Protein Degradation Applications.
Ward CC, Kleinman JI, Brittain SM, Lee PS, Chung CYS, Kim K, Petri Y, Thomas JR, Tallarico JA, McKenna JM, Schirle M, Nomura DK
ACS chemical biology 2019 Nov 15;14(11):2430-2440
ACS chemical biology 2019 Nov 15;14(11):2430-2440
A dual functional ruthenium arene complex induces differentiation and apoptosis of acute promyelocytic leukemia cells.
Huang H, Cao K, Kong Y, Yuan S, Liu H, Wang Y, Liu Y
Chemical science 2019 Nov 14;10(42):9721-9728
Chemical science 2019 Nov 14;10(42):9721-9728
SPOP inhibits mice pancreatic stellate cell activation by promoting FADD degradation in cerulein-induced chronic pancreatitis.
Tan P, Wang A, Chen H, Du Y, Qian B, Shi H, Zhang Y, Xia X, Fu W
Experimental cell research 2019 Nov 1;384(1):111606
Experimental cell research 2019 Nov 1;384(1):111606
Prematurity blunts the feeding-induced stimulation of translation initiation signaling and protein synthesis in muscle of neonatal piglets.
Naberhuis JK, Suryawan A, Nguyen HV, Hernandez-Garcia A, Cruz SM, Lau PE, Olutoye OO, Stoll B, Burrin DG, Fiorotto ML, Davis TA
American journal of physiology. Endocrinology and metabolism 2019 Nov 1;317(5):E839-E851
American journal of physiology. Endocrinology and metabolism 2019 Nov 1;317(5):E839-E851
Aurone derivatives as Vps34 inhibitors that modulate autophagy.
Li G, Boyle JW, Ko CN, Zeng W, Wong VKW, Wan JB, Chan PWH, Ma DL, Leung CH
Acta pharmaceutica Sinica. B 2019 May;9(3):537-544
Acta pharmaceutica Sinica. B 2019 May;9(3):537-544
Regulation of insulin resistance by targeting the insulin-like growth factor 1 receptor with microRNA-122-5p in hepatic cells.
Dong L, Hou X, Liu F, Tao H, Zhang Y, Zhao H, Song G
Cell biology international 2019 May;43(5):553-564
Cell biology international 2019 May;43(5):553-564
RPS7 promotes cell migration through targeting epithelial-mesenchymal transition in prostate cancer.
Wen Y, An Z, Qiao B, Zhang C, Zhang Z
Urologic oncology 2019 May;37(5):297.e1-297.e7
Urologic oncology 2019 May;37(5):297.e1-297.e7
Identification of genes with universally upregulated or downregulated expressions in colorectal cancer.
Song K, Su W, Liu Y, Zhang J, Liang Q, Li N, Guan Q, He J, Bai X, Zhao W, Guo Z
Journal of gastroenterology and hepatology 2019 May;34(5):880-889
Journal of gastroenterology and hepatology 2019 May;34(5):880-889
Taurine alleviates repression of betaine-homocysteine S-methyltransferase and significantly improves the efficacy of long-term betaine treatment in a mouse model of cystathionine β-synthase-deficient homocystinuria.
Maclean KN, Jiang H, Phinney WN, Keating AK, Hurt KJ, Stabler SP
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 May;33(5):6339-6353
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 May;33(5):6339-6353
Adipose-Specific Lipin-1 Overexpression Renders Hepatic Ferroptosis and Exacerbates Alcoholic Steatohepatitis in Mice.
Zhou Z, Ye TJ, Bonavita G, Daniels M, Kainrad N, Jogasuria A, You M
Hepatology communications 2019 May;3(5):656-669
Hepatology communications 2019 May;3(5):656-669
Serine/arginine protein-specific kinase 2 promotes the development and progression of pancreatic cancer by downregulating Numb and p53.
Wang G, Sheng W, Shi X, Li X, Zhou J, Dong M
The FEBS journal 2019 May;286(9):1668-1682
The FEBS journal 2019 May;286(9):1668-1682
MicroRNA-92a promotes vascular smooth muscle cell proliferation and migration through the ROCK/MLCK signalling pathway.
Wang J, Zhang C, Li C, Zhao D, Li S, Ma L, Cui Y, Wei X, Zhao Y, Gao Y
Journal of cellular and molecular medicine 2019 May;23(5):3696-3710
Journal of cellular and molecular medicine 2019 May;23(5):3696-3710
Ectopic expression of miR-944 impairs colorectal cancer cell proliferation and invasion by targeting GATA binding protein 6.
Tang JT, Zhao J, Sheng W, Zhou JP, Dong Q, Dong M
Journal of cellular and molecular medicine 2019 May;23(5):3483-3494
Journal of cellular and molecular medicine 2019 May;23(5):3483-3494
The pattern-recognition molecule mindin binds integrin Mac-1 to promote macrophage phagocytosis via Syk activation and NF-κB p65 translocation.
Liu YS, Wang LF, Cheng XS, Huo YN, Ouyang XM, Liang LY, Lin Y, Wu JF, Ren JL, Guleng B
Journal of cellular and molecular medicine 2019 May;23(5):3402-3416
Journal of cellular and molecular medicine 2019 May;23(5):3402-3416
The RNA N(6)-methyladenosine modification landscape of human fetal tissues.
Xiao S, Cao S, Huang Q, Xia L, Deng M, Yang M, Jia G, Liu X, Shi J, Wang W, Li Y, Liu S, Zhu H, Tan K, Luo Q, Zhong M, He C, Xia L
Nature cell biology 2019 May;21(5):651-661
Nature cell biology 2019 May;21(5):651-661
ERα and Wnt/β‑catenin signaling pathways are involved in angelicin‑dependent promotion of osteogenesis.
Ge L, Cui Y, Liu B, Yin X, Pang J, Han J
Molecular medicine reports 2019 May;19(5):3469-3476
Molecular medicine reports 2019 May;19(5):3469-3476
β-Catenin and Yes-Associated Protein 1 Cooperate in Hepatoblastoma Pathogenesis.
Min Q, Molina L, Li J, Adebayo Michael AO, Russell JO, Preziosi ME, Singh S, Poddar M, Matz-Soja M, Ranganathan S, Bell AW, Gebhardt R, Gaunitz F, Yu J, Tao J, Monga SP
The American journal of pathology 2019 May;189(5):1091-1104
The American journal of pathology 2019 May;189(5):1091-1104
A novel function of anaphase promoting complex subunit 10 in tumor progression in non-small cell lung cancer.
Wang Y, Han T, Gan M, Guo M, Xie C, Jin J, Zhang S, Wang P, Cao J, Wang JB
Cell cycle (Georgetown, Tex.) 2019 May;18(9):1019-1032
Cell cycle (Georgetown, Tex.) 2019 May;18(9):1019-1032
Demethylation of the HACE1 gene promoter inhibits the proliferation of human liver cancer cells.
Yu Z, Li Y, Han T, Liu Z
Oncology letters 2019 May;17(5):4361-4368
Oncology letters 2019 May;17(5):4361-4368
Upregulated forkhead-box A3 elevates the expression of forkhead-box A1 and forkhead-box A2 to promote metastasis in esophageal cancer.
Chen B, Yu J, Lu L, Dong F, Zhou F, Tao X, Sun E
Oncology letters 2019 May;17(5):4351-4360
Oncology letters 2019 May;17(5):4351-4360
Nano hydroxyapatite induces glioma cell apoptosis by suppressing NF-κB signaling pathway.
Guo G, Tian A, Lan X, Fu C, Yan Z, Wang C
Experimental and therapeutic medicine 2019 May;17(5):4080-4088
Experimental and therapeutic medicine 2019 May;17(5):4080-4088
Attenuation of interferon regulatory factor 7 activity in local infectious sites of trachea and lung for preventing the development of acute lung injury caused by influenza A virus.
Yang L, Tu L, Zhao P, Wang Y, Wang S, Lu W, Wang Y, Li X, Yu Y, Hua S, Wang L
Immunology 2019 May;157(1):37-51
Immunology 2019 May;157(1):37-51
SMCR8 negatively regulates AKT and MTORC1 signaling to modulate lysosome biogenesis and tissue homeostasis.
Lan Y, Sullivan PM, Hu F
Autophagy 2019 May;15(5):871-885
Autophagy 2019 May;15(5):871-885
The ALS-FTD-linked gene product, C9orf72, regulates neuronal morphogenesis via autophagy.
Ho WY, Tai YK, Chang JC, Liang J, Tyan SH, Chen S, Guan JL, Zhou H, Shen HM, Koo E, Ling SC
Autophagy 2019 May;15(5):827-842
Autophagy 2019 May;15(5):827-842
FAM175B promotes apoptosis by inhibiting ATF4 ubiquitination in esophageal squamous cell carcinoma.
Zhao Y, Yu Y, Li H, Zhang Z, Guo S, Zhu S, Guo Q, Li P, Min L, Zhang S
Molecular oncology 2019 May;13(5):1150-1165
Molecular oncology 2019 May;13(5):1150-1165
Expression of DEC2 enhances chemosensitivity by inhibiting STAT5A in gastric cancer.
Li H, Ma X, Xiao D, Jia Y, Wang Y
Journal of cellular biochemistry 2019 May;120(5):8447-8456
Journal of cellular biochemistry 2019 May;120(5):8447-8456
Nrf2 controls iron homeostasis in haemochromatosis and thalassaemia via Bmp6 and hepcidin.
Lim PJ, Duarte TL, Arezes J, Garcia-Santos D, Hamdi A, Pasricha SR, Armitage AE, Mehta H, Wideman S, Santos AG, Santos-Gonçalves A, Morovat A, Hughes JR, Soilleux E, Wang CY, Bayer AL, Klenerman P, Willberg CB, Hartley RC, Murphy MP, Babitt JL, Ponka P, Porto G, Drakesmith H
Nature metabolism 2019 May;1(5):519-531
Nature metabolism 2019 May;1(5):519-531
Sox17 is required for endothelial regeneration following inflammation-induced vascular injury.
Liu M, Zhang L, Marsboom G, Jambusaria A, Xiong S, Toth PT, Benevolenskaya EV, Rehman J, Malik AB
Nature communications 2019 May 9;10(1):2126
Nature communications 2019 May 9;10(1):2126
Inhibiting Glutamine-Dependent mTORC1 Activation Ameliorates Liver Cancers Driven by β-Catenin Mutations.
Adebayo Michael AO, Ko S, Tao J, Moghe A, Yang H, Xu M, Russell JO, Pradhan-Sundd T, Liu S, Singh S, Poddar M, Monga JS, Liu P, Oertel M, Ranganathan S, Singhi A, Rebouissou S, Zucman-Rossi J, Ribback S, Calvisi D, Qvartskhava N, Görg B, Häussinger D, Chen X, Monga SP
Cell metabolism 2019 May 7;29(5):1135-1150.e6
Cell metabolism 2019 May 7;29(5):1135-1150.e6
Thyrotropin aggravates atherosclerosis by promoting macrophage inflammation in plaques.
Yang C, Lu M, Chen W, He Z, Hou X, Feng M, Zhang H, Bo T, Zhou X, Yu Y, Zhang H, Zhao M, Wang L, Yu C, Gao L, Jiang W, Zhang Q, Zhao J
The Journal of experimental medicine 2019 May 6;216(5):1182-1198
The Journal of experimental medicine 2019 May 6;216(5):1182-1198
Adipose HuR protects against diet-induced obesity and insulin resistance.
Li J, Gong L, Liu S, Zhang Y, Zhang C, Tian M, Lu H, Bu P, Yang J, Ouyang C, Jiang X, Wu J, Zhang Y, Min Q, Zhang C, Zhang W
Nature communications 2019 May 30;10(1):2375
Nature communications 2019 May 30;10(1):2375
USP36 protects proximal tubule cells from ischemic injury by stabilizing c-Myc and SOD2.
Liu Q, Sheng W, Ma Y, Zhen J, Roy S, Alvira Jafar C, Xin W, Wan Q
Biochemical and biophysical research communications 2019 May 28;513(2):502-508
Biochemical and biophysical research communications 2019 May 28;513(2):502-508
p53 suppression is essential for oncogenic SPAG5 upregulation in lung adenocarcinoma.
Wang T, Li K, Song H, Xu D, Liao Y, Jing B, Guo W, Hu M, Kuang Y, Sun B, Ling J, Zhang T, Xu J, Yao F, Deng J
Biochemical and biophysical research communications 2019 May 28;513(2):319-325
Biochemical and biophysical research communications 2019 May 28;513(2):319-325
HMGB1 contributes to SASH1 methylation to attenuate astrocyte adhesion.
Wu R, Yan Y, Ma C, Chen H, Dong Z, Wang Y, Liu Y, Liu M, Yang L
Cell death & disease 2019 May 28;10(6):417
Cell death & disease 2019 May 28;10(6):417
Inhibition of the IGF-1-PI3K-Akt-mTORC2 pathway in lipid rafts increases neuronal vulnerability in a genetic lysosomal glycosphingolipidosis.
Sural-Fehr T, Singh H, Cantuti-Catelvetri L, Zhu H, Marshall MS, Rebiai R, Jastrzebski MJ, Givogri MI, Rasenick MM, Bongarzone ER
Disease models & mechanisms 2019 May 23;12(5)
Disease models & mechanisms 2019 May 23;12(5)
PLA Electrospun Scaffolds for Three-Dimensional Triple-Negative Breast Cancer Cell Culture.
Polonio-Alcalá E, Rabionet M, Gallardo X, Angelats D, Ciurana J, Ruiz-Martínez S, Puig T
Polymers 2019 May 23;11(5)
Polymers 2019 May 23;11(5)
Shen Shuai IIRecipe attenuates renal injury and fibrosis in chronic kidney disease by regulating NLRP3 inflammasome and Sirt1/Smad3 deacetylation pathway.
Wang M, Yang L, Yang J, Wang C
BMC complementary and alternative medicine 2019 May 22;19(1):107
BMC complementary and alternative medicine 2019 May 22;19(1):107
Isodunnianol alleviates doxorubicin-induced myocardial injury by activating protective autophagy.
Chen C, Jiang L, Zhang M, Pan X, Peng C, Huang W, Jiang Q
Food & function 2019 May 22;10(5):2651-2657
Food & function 2019 May 22;10(5):2651-2657
Estrogen negatively regulates the renal epithelial sodium channel (ENaC) by promoting Derlin-1 expression and AMPK activation.
Zhang X, Ge Y, Bukhari AA, Zhu Q, Shen Y, Li M, Sun H, Su D, Liang X
Experimental & molecular medicine 2019 May 21;51(5):1-12
Experimental & molecular medicine 2019 May 21;51(5):1-12
Tumor Cell "Slimming" Regulates Tumor Progression through PLCL1/UCP1-Mediated Lipid Browning.
Xiong Z, Xiao W, Bao L, Xiong W, Xiao H, Qu Y, Yuan C, Ruan H, Cao Q, Wang K, Song Z, Wang C, Hu W, Ru Z, Tong J, Cheng G, Xu T, Meng X, Shi J, Chen Z, Yang H, Chen K, Zhang X
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2019 May 17;6(10):1801862
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2019 May 17;6(10):1801862
M2 macrophages promote NSCLC metastasis by upregulating CRYAB.
Guo Z, Song J, Hao J, Zhao H, Du X, Li E, Kuang Y, Yang F, Wang W, Deng J, Wang Q
Cell death & disease 2019 May 16;10(6):377
Cell death & disease 2019 May 16;10(6):377
Triptolide prevents proliferation and migration of Esophageal Squamous Cell Cancer via MAPK/ERK signaling pathway.
Yanchun M, Yi W, Lu W, Yu Q, Jian Y, Pengzhou K, Ting Y, Hongyi L, Fang W, Xiaolong C, Yongping C
European journal of pharmacology 2019 May 15;851:43-51
European journal of pharmacology 2019 May 15;851:43-51
Oral Administration of a Select Mixture of Lactobacillus and Bacillus Alleviates Inflammation and Maintains Mucosal Barrier Integrity in the Ileum of Pigs Challenged with Salmonella Infantis.
Liu X, Xia B, He T, Li D, Su JH, Guo L, Wang JF, Zhu YH
Microorganisms 2019 May 15;7(5)
Microorganisms 2019 May 15;7(5)
Hic-5 regulates Src-induced invadopodia rosette formation and organization.
Gulvady AC, Forsythe IJ, Turner CE
Molecular biology of the cell 2019 May 15;30(11):1298-1313
Molecular biology of the cell 2019 May 15;30(11):1298-1313
FGFR2 Promotes Expression of PD-L1 in Colorectal Cancer via the JAK/STAT3 Signaling Pathway.
Li P, Huang T, Zou Q, Liu D, Wang Y, Tan X, Wei Y, Qiu H
Journal of immunology (Baltimore, Md. : 1950) 2019 May 15;202(10):3065-3075
Journal of immunology (Baltimore, Md. : 1950) 2019 May 15;202(10):3065-3075
Sodium ferulate protects against influenza virus infection by activation of the TLR7/9-MyD88-IRF7 signaling pathway and inhibition of the NF-κB signaling pathway.
Zhu Y, Shao Y, Qu X, Guo J, Yang J, Zhou Z, Wang S
Biochemical and biophysical research communications 2019 May 14;512(4):793-798
Biochemical and biophysical research communications 2019 May 14;512(4):793-798
The Glycoprotein and Nucleocapsid Protein of Hantaviruses Manipulate Autophagy Flux to Restrain Host Innate Immune Responses.
Wang K, Ma H, Liu H, Ye W, Li Z, Cheng L, Zhang L, Lei Y, Shen L, Zhang F
Cell reports 2019 May 14;27(7):2075-2091.e5
Cell reports 2019 May 14;27(7):2075-2091.e5
ELF4 facilitates innate host defenses against Plasmodium by activating transcription of Pf4 and Ppbp.
Wang D, Zhang Z, Cui S, Zhao Y, Craft S, Fikrig E, You F
The Journal of biological chemistry 2019 May 10;294(19):7787-7796
The Journal of biological chemistry 2019 May 10;294(19):7787-7796
Cynomorium songaricum Rupr demonstrates phytoestrogenic or phytoandrogenic like activities that attenuates benign prostatic hyperplasia via regulating steroid 5-α-reductase.
Tao R, Miao L, Yu X, Orgah JO, Barnabas O, Chang Y, Liu E, Fan G, Gao X
Journal of ethnopharmacology 2019 May 10;235:65-74
Journal of ethnopharmacology 2019 May 10;235:65-74
Anterior Gradient-2 monoclonal antibody inhibits lung cancer growth and metastasis by upregulating p53 pathway and without exerting any toxicological effects: A preclinical study.
Negi H, Merugu SB, Mangukiya HB, Li Z, Zhou B, Sehar Q, Kamle S, Yunus FU, Mashausi DS, Wu Z, Li D
Cancer letters 2019 May 1;449:125-134
Cancer letters 2019 May 1;449:125-134
USP39 regulates DNA damage response and chemo-radiation resistance by deubiquitinating and stabilizing CHK2.
Wu J, Chen Y, Geng G, Li L, Yin P, Nowsheen S, Li Y, Wu C, Liu J, Zhao F, Kim W, Zhou Q, Huang J, Guo G, Zhang C, Tu X, Gao X, Lou Z, Luo K, Qiao H, Yuan J
Cancer letters 2019 May 1;449:114-124
Cancer letters 2019 May 1;449:114-124
Astragaloside IV Regulates the PI3K/Akt/HO-1 Signaling Pathway and Inhibits H9c2 Cardiomyocyte Injury Induced by Hypoxia-Reoxygenation.
Yang P, Zhou Y, Xia Q, Yao L, Chang X
Biological & pharmaceutical bulletin 2019 May 1;42(5):721-727
Biological & pharmaceutical bulletin 2019 May 1;42(5):721-727
Inactivation of Cyclic AMP Response Element Transcription Caused by Constitutive p38 Activation Is Mediated by Hyperphosphorylation-Dependent CRTC2 Nucleocytoplasmic Transport.
Ma H, Liu Z, Zhong CQ, Liu Y, Zhang Z, Liang Y, Li J, Han S, Han J
Molecular and cellular biology 2019 May 1;39(9)
Molecular and cellular biology 2019 May 1;39(9)
Fatty acid-binding protein 3 contributes to ischemic heart injury by regulating cardiac myocyte apoptosis and MAPK pathways.
Zhuang L, Li C, Chen Q, Jin Q, Wu L, Lu L, Yan X, Chen K
American journal of physiology. Heart and circulatory physiology 2019 May 1;316(5):H971-H984
American journal of physiology. Heart and circulatory physiology 2019 May 1;316(5):H971-H984
Inhibition of mitochondrial complex I activity attenuates neointimal hyperplasia by inhibiting smooth muscle cell proliferation and migration.
Yin J, Xia W, Wu M, Zhang Y, Huang S, Zhang A, Jia Z
Chemico-biological interactions 2019 May 1;304:73-82
Chemico-biological interactions 2019 May 1;304:73-82
Reactivation of nonsense-mediated mRNA decay protects against C9orf72 dipeptide-repeat neurotoxicity.
Xu W, Bao P, Jiang X, Wang H, Qin M, Wang R, Wang T, Yang Y, Lorenzini I, Liao L, Sattler R, Xu J
Brain : a journal of neurology 2019 May 1;142(5):1349-1364
Brain : a journal of neurology 2019 May 1;142(5):1349-1364
Sirt3 mediates the protective effect of hydrogen in inhibiting ROS-induced retinal senescence.
Li R, Liu Y, Xie J, Huang X, Zhang L, Liu H, Li L
Free radical biology & medicine 2019 May 1;135:116-124
Free radical biology & medicine 2019 May 1;135:116-124
Oxytocin facilitates the proliferation, migration and osteogenic differentiation of human periodontal stem cells in vitro.
Ge B, Liu H, Liang Q, Shang L, Wang T, Ge S
Archives of oral biology 2019 Mar;99:126-133
Archives of oral biology 2019 Mar;99:126-133
Nr5a2 promotes cancer stem cell properties and tumorigenesis in nonsmall cell lung cancer by regulating Nanog.
Ye T, Li J, Sun Z, Liu Y, Kong L, Zhou S, Tang J, Wang J, Xing HR
Cancer medicine 2019 Mar;8(3):1232-1245
Cancer medicine 2019 Mar;8(3):1232-1245
MicroRNA-186 is associated with hypoxia-inducible factor-1α expression in chronic obstructive pulmonary disease.
Lin L, Sun J, Wu D, Lin D, Sun D, Li Q, Chen J, Niu H, He P, Ding Y
Molecular genetics & genomic medicine 2019 Mar;7(3):e531
Molecular genetics & genomic medicine 2019 Mar;7(3):e531
Gallic Acid Suppresses Cardiac Hypertrophic Remodeling and Heart Failure.
Yan X, Zhang YL, Zhang L, Zou LX, Chen C, Liu Y, Xia YL, Li HH
Molecular nutrition & food research 2019 Mar;63(5):e1800807
Molecular nutrition & food research 2019 Mar;63(5):e1800807
Herbal decoctosome is a novel form of medicine.
Li X, Liang Z, Du J, Wang Z, Mei S, Li Z, Zhao Y, Zhao D, Ma Y, Ye J, Xu J, Zhao Y, Chang J, Qin Y, Yu L, Wang C, Jiang C
Science China. Life sciences 2019 Mar;62(3):333-348
Science China. Life sciences 2019 Mar;62(3):333-348
Pb disrupts autophagic flux through inhibiting the formation and activity of lysosomes in neural cells.
Gu X, Han M, Du Y, Wu Y, Xu Y, Zhou X, Ye D, Wang HL
Toxicology in vitro : an international journal published in association with BIBRA 2019 Mar;55:43-50
Toxicology in vitro : an international journal published in association with BIBRA 2019 Mar;55:43-50
Role of heparan sulfate in the Zika virus entry, replication, and cell death.
Gao H, Lin Y, He J, Zhou S, Liang M, Huang C, Li X, Liu C, Zhang P
Virology 2019 Mar;529:91-100
Virology 2019 Mar;529:91-100
NS38 is required for aquareovirus replication via interaction with viral core proteins and host eIF3A.
Zhang J, Guo H, Zhang F, Chen Q, Chang M, Fang Q
Virology 2019 Mar;529:216-225
Virology 2019 Mar;529:216-225
Continuous translation of circularized mRNA improves recombinant protein titer.
Costello A, Lao NT, Barron N, Clynes M
Metabolic engineering 2019 Mar;52:284-292
Metabolic engineering 2019 Mar;52:284-292
Regulation of Neurotransmitter Release by Amyloid Precursor Protein Through Synapsin Phosphorylation.
Liu A, Zhang Y, Han L, He G, Xie W, Zhou Z, Jia Z
Neurochemical research 2019 Mar;44(3):683-691
Neurochemical research 2019 Mar;44(3):683-691
Bromodomain‑containing protein 7 sensitizes breast cancer cells to paclitaxel by activating Bcl2‑antagonist/killer protein.
Ma J, Niu W, Wang X, Zhou Y, Wang H, Liu F, Liu Y, Guo J, Xiong W, Zeng Z, Fan S, Li X, Nie X, Li G, Gui R, Luo Y, Zhou M
Oncology reports 2019 Mar;41(3):1487-1496
Oncology reports 2019 Mar;41(3):1487-1496
miR-4739 mediates pleural fibrosis by targeting bone morphogenetic protein 7.
Wang M, Xiong L, Jiang LJ, Lu YZ, Liu F, Song LJ, Xiang F, He XL, Yu F, Shuai SY, Ma WL, Ye H
EBioMedicine 2019 Mar;41:670-682
EBioMedicine 2019 Mar;41:670-682
The HNF1α-Regulated LncRNA HNF1α-AS1 Is Involved in the Regulation of Cytochrome P450 Expression in Human Liver Tissues and Huh7 Cells.
Wang Y, Yan L, Liu J, Chen S, Liu G, Nie Y, Wang P, Yang W, Chen L, Zhong X, Han S, Zhang L
The Journal of pharmacology and experimental therapeutics 2019 Mar;368(3):353-362
The Journal of pharmacology and experimental therapeutics 2019 Mar;368(3):353-362
3D human bone marrow stromal and endothelial cell spheres promote bone healing in an osteogenic niche.
Inglis S, Kanczler JM, Oreffo ROC
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 Mar;33(3):3279-3290
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 Mar;33(3):3279-3290
Oncostatin M-induced upregulation of SDF-1 improves Bone marrow stromal cell migration in a rat middle cerebral artery occlusion stroke model.
Han J, Feng Z, Xie Y, Li F, Lv B, Hua T, Zhang Z, Sun C, Su D, Ouyang Q, Cai Y, Zou Y, Tang Y, Sun H, Jiang X
Experimental neurology 2019 Mar;313:49-59
Experimental neurology 2019 Mar;313:49-59
PARylation regulates stress granule dynamics, phase separation, and neurotoxicity of disease-related RNA-binding proteins.
Duan Y, Du A, Gu J, Duan G, Wang C, Gui X, Ma Z, Qian B, Deng X, Zhang K, Sun L, Tian K, Zhang Y, Jiang H, Liu C, Fang Y
Cell research 2019 Mar;29(3):233-247
Cell research 2019 Mar;29(3):233-247
β‑elemene inhibits oxygen‑induced retinal neovascularization via promoting miR‑27a and reducing VEGF expression.
Zhang W, Chen L, Geng J, Liu L, Xu L
Molecular medicine reports 2019 Mar;19(3):2307-2316
Molecular medicine reports 2019 Mar;19(3):2307-2316
Modulation of α-adrenoceptor signalling protects photoreceptors after retinal detachment by inhibiting oxidative stress and inflammation.
Li T, Yang S, She X, Yan Q, Zhang P, Zhu H, Wang F, Luo X, Sun X
British journal of pharmacology 2019 Mar;176(6):801-813
British journal of pharmacology 2019 Mar;176(6):801-813
NF-κB and Poly (ADP-ribose) Polymerase 1 Form a Positive Feedback Loop that Regulates DNA Repair in Acute Myeloid Leukemia Cells.
Li D, Luo Y, Chen X, Zhang L, Wang T, Zhuang Y, Fan Y, Xu J, Chen Y, Wu L
Molecular cancer research : MCR 2019 Mar;17(3):761-772
Molecular cancer research : MCR 2019 Mar;17(3):761-772
miRNA profiling in the hippocampus of attention-deficit/hyperactivity disorder rats.
Tian T, Zhang Y, Wu T, Yang L, Chen C, Li N, Li Y, Xu S, Fu Z, Cui X, Ji C, Chi X, Tong M, Chen R, Hong Q, Hu Y
Journal of cellular biochemistry 2019 Mar;120(3):3621-3629
Journal of cellular biochemistry 2019 Mar;120(3):3621-3629
MET mutation causes muscular dysplasia and arthrogryposis.
Zhou H, Lian C, Wang T, Yang X, Xu C, Su D, Zheng S, Huang X, Liao Z, Zhou T, Qiu X, Chen Y, Gao B, Li Y, Wang X, You G, Fu Q, Gurnett C, Huang D, Su P
EMBO molecular medicine 2019 Mar;11(3)
EMBO molecular medicine 2019 Mar;11(3)
MLKL deficiency inhibits DSS-induced colitis independent of intestinal microbiota.
Zhang J, Qin D, Yang YJ, Hu GQ, Qin XX, Du CT, Chen W
Molecular immunology 2019 Mar;107:132-141
Molecular immunology 2019 Mar;107:132-141
Combinatory FK506 and Minocycline Treatment Alleviates Prion-Induced Neurodegenerative Events via Caspase-Mediated MAPK-NRF2 Pathway.
Shah SZA, Zhao D, Taglialatela G, Hussain T, Dong H, Sabir N, Mangi MH, Wu W, Lai M, Zhang X, Duan Y, Wang L, Zhou X, Yang L
International journal of molecular sciences 2019 Mar 6;20(5)
International journal of molecular sciences 2019 Mar 6;20(5)
Circadian control of stress granules by oscillating EIF2α.
Wang R, Jiang X, Bao P, Qin M, Xu J
Cell death & disease 2019 Mar 4;10(3):215
Cell death & disease 2019 Mar 4;10(3):215
Neuroprotective Effect of Dioscin on the Aging Brain.
Qi Y, Li R, Xu L, Yin L, Xu Y, Han X, Peng J
Molecules (Basel, Switzerland) 2019 Mar 30;24(7)
Molecules (Basel, Switzerland) 2019 Mar 30;24(7)
Silencing of XRCC4 increases radiosensitivity of triple-negative breast cancer cells.
Wen Y, Dai G, Wang L, Fu K, Zuo S
Bioscience reports 2019 Mar 29;39(3)
Bioscience reports 2019 Mar 29;39(3)
Cysteine Dioxygenase Regulates the Epithelial Morphogenesis of Mammary Gland via Cysteine Sulfinic Acid.
Zhao J, Han Y, Ma X, Zhou Y, Yuan S, Shen Q, Ye G, Liu H, Fu P, Zhang G, Qiao B, Liu A
iScience 2019 Mar 29;13:173-189
iScience 2019 Mar 29;13:173-189
Viral-Mediated AURKB Cleavage Promotes Cell Segregation and Tumorigenesis.
Zhu Q, Ding L, Zi Z, Gao S, Wang C, Wang Y, Zhu C, Yuan Z, Wei F, Cai Q
Cell reports 2019 Mar 26;26(13):3657-3671.e5
Cell reports 2019 Mar 26;26(13):3657-3671.e5
MicroRNA-29a Disrupts DNMT3b to Ameliorate Diet-Induced Non-Alcoholic Steatohepatitis in Mice.
Yang YL, Kuo HC, Wang FS, Huang YH
International journal of molecular sciences 2019 Mar 26;20(6)
International journal of molecular sciences 2019 Mar 26;20(6)
H(2)S restores the cardioprotective effects of ischemic post-conditioning by upregulating HB-EGF/EGFR signaling.
Zhang Y, Gao J, Sun W, Wen X, Xi Y, Wang Y, Wei C, Xu C, Li H
Aging 2019 Mar 26;11(6):1745-1758
Aging 2019 Mar 26;11(6):1745-1758
Ribosomal Proteins Regulate MHC Class I Peptide Generation for Immunosurveillance.
Wei J, Kishton RJ, Angel M, Conn CS, Dalla-Venezia N, Marcel V, Vincent A, Catez F, Ferré S, Ayadi L, Marchand V, Dersh D, Gibbs JS, Ivanov IP, Fridlyand N, Couté Y, Diaz JJ, Qian SB, Staudt LM, Restifo NP, Yewdell JW
Molecular cell 2019 Mar 21;73(6):1162-1173.e5
Molecular cell 2019 Mar 21;73(6):1162-1173.e5
Genetically Encoded FapR-NLuc as a Biosensor to Determine Malonyl-CoA in Situ at Subcellular Scales.
Du Y, Hu H, Pei X, Du K, Wei T
Bioconjugate chemistry 2019 Mar 20;30(3):826-832
Bioconjugate chemistry 2019 Mar 20;30(3):826-832
Discovery of human TyrRS inhibitors by structure-based virtual screening, structural optimization, and bioassays.
Huang S, Wang X, Lin G, Cheng J, Chen X, Sun W, Xiang R, Yu Y, Li L, Yang S
RSC advances 2019 Mar 15;9(16):9323-9330
RSC advances 2019 Mar 15;9(16):9323-9330
Detecting Secretory Proteins by Acoustic Droplet Ejection in Multiplexed High-Throughput Applications.
Iannotti MJ, MacArthur R, Jones R, Tao D, Singeç I, Michael S, Inglese J
ACS chemical biology 2019 Mar 15;14(3):497-505
ACS chemical biology 2019 Mar 15;14(3):497-505
A GPR17-cAMP-Lactate Signaling Axis in Oligodendrocytes Regulates Whole-Body Metabolism.
Ou Z, Ma Y, Sun Y, Zheng G, Wang S, Xing R, Chen X, Han Y, Wang J, Lu QR, Zhao TJ, Chen Y
Cell reports 2019 Mar 12;26(11):2984-2997.e4
Cell reports 2019 Mar 12;26(11):2984-2997.e4
p53-targeted lincRNA-p21 acts as a tumor suppressor by inhibiting JAK2/STAT3 signaling pathways in head and neck squamous cell carcinoma.
Jin S, Yang X, Li J, Yang W, Ma H, Zhang Z
Molecular cancer 2019 Mar 11;18(1):38
Molecular cancer 2019 Mar 11;18(1):38
Porcine Hemagglutinating Encephalomyelitis Virus Activation of the Integrin α5β1-FAK-Cofilin Pathway Causes Cytoskeletal Rearrangement To Promote Its Invasion of N2a Cells.
Lv X, Li Z, Guan J, Hu S, Zhang J, Lan Y, Zhao K, Lu H, Song D, He H, Gao F, He W
Journal of virology 2019 Mar 1;93(5)
Journal of virology 2019 Mar 1;93(5)
PRL-3 Promotes Ubiquitination and Degradation of AURKA and Colorectal Cancer Progression via Dephosphorylation of FZR1.
Zhang C, Qu L, Lian S, Meng L, Min L, Liu J, Song Q, Shen L, Shou C
Cancer research 2019 Mar 1;79(5):928-940
Cancer research 2019 Mar 1;79(5):928-940
HOXD-AS1 promotes the epithelial to mesenchymal transition of ovarian cancer cells by regulating miR-186-5p and PIK3R3.
Dong S, Wang R, Wang H, Ding Q, Zhou X, Wang J, Zhang K, Long Y, Lu S, Hong T, Ren H, Wong K, Sheng X, Wang Y, Zeng Y
Journal of experimental & clinical cancer research : CR 2019 Mar 1;38(1):110
Journal of experimental & clinical cancer research : CR 2019 Mar 1;38(1):110
Candidate-based screening via gene modulation in human neurons and astrocytes implicates FERMT2 in Aβ and TAU proteostasis.
Sullivan SE, Liao M, Smith RV, White C, Lagomarsino VN, Xu J, Taga M, Bennett DA, De Jager PL, Young-Pearse TL
Human molecular genetics 2019 Mar 1;28(5):718-735
Human molecular genetics 2019 Mar 1;28(5):718-735
In Vitro and In Vivo Anti-Inflammatory Effects of Polyphyllin VII through Downregulating MAPK and NF-κB Pathways.
Zhang C, Li C, Jia X, Wang K, Tu Y, Wang R, Liu K, Lu T, He C
Molecules (Basel, Switzerland) 2019 Mar 1;24(5)
Molecules (Basel, Switzerland) 2019 Mar 1;24(5)
Gα(i2) Signaling Regulates Inflammasome Priming and Cytokine Production by Biasing Macrophage Phenotype Determination.
Vural A, Nabar NR, Hwang IY, Sohn S, Park C, Karlsson MCI, Blumer JB, Kehrl JH
Journal of immunology (Baltimore, Md. : 1950) 2019 Mar 1;202(5):1510-1520
Journal of immunology (Baltimore, Md. : 1950) 2019 Mar 1;202(5):1510-1520
Molecular characterization of caspase-8-like and its expression induced by microcystin-LR in grass carp (Ctenopharygodon idella).
Wei L, He L, Fu J, Liu Y, Ruan J, Liu L, Zhong Q
Fish & shellfish immunology 2019 Jun;89:727-735
Fish & shellfish immunology 2019 Jun;89:727-735
Defective Central Immune Tolerance Induced by High-Dose D-Galactose Resembles Aging.
Du HM, Wang YJ, Liu X, Wang SL, Wu SM, Yuan Z, Zhu XK
Biochemistry. Biokhimiia 2019 Jun;84(6):617-626
Biochemistry. Biokhimiia 2019 Jun;84(6):617-626
Exosomal cyclophilin A as a novel noninvasive biomarker for Epstein-Barr virus associated nasopharyngeal carcinoma.
Liu L, Zuo L, Yang J, Xin S, Zhang J, Zhou J, Li G, Tang J, Lu J
Cancer medicine 2019 Jun;8(6):3142-3151
Cancer medicine 2019 Jun;8(6):3142-3151
Activation of cGMP/PKG/p65 signaling associated with PDE5-Is downregulates CCL5 secretion by CD8 (+) T cells in benign prostatic hyperplasia.
Jin S, Xiang P, Liu J, Yang Y, Hu S, Sheng J, He Q, Yu W, Han W, Jin J, Peng J
The Prostate 2019 Jun;79(8):909-919
The Prostate 2019 Jun;79(8):909-919
Minimally modified low-density lipoprotein upregulates the ET(B) and α(1) receptors in mouse mesenteric arteries in vivo by activating the PI3K/Akt pathway.
Zeng ZS, Lin J, Xu CB, Cao L, Chen C, Li J
The Journal of pharmacy and pharmacology 2019 Jun;71(6):937-944
The Journal of pharmacy and pharmacology 2019 Jun;71(6):937-944
Deficiency of ZnT8 Promotes Adiposity and Metabolic Dysfunction by Increasing Peripheral Serotonin Production.
Mao Z, Lin H, Su W, Li J, Zhou M, Li Z, Zhou B, Yang Q, Zhou M, Pan K, He J, Zhang W
Diabetes 2019 Jun;68(6):1197-1209
Diabetes 2019 Jun;68(6):1197-1209
Activated CRH receptors inhibit autophagy by repressing conversion of LC3BI to LC3BII.
Jin L, Qian Y, Zhou J, Dai L, Cao C, Zhu C, Li S
Cellular signalling 2019 Jun;58:119-130
Cellular signalling 2019 Jun;58:119-130
A comprehensive study on donor-matched comparisons of three types of mesenchymal stem cells-containing cells from human dental tissue.
Xing Y, Zhang Y, Wu X, Zhao B, Ji Y, Xu X
Journal of periodontal research 2019 Jun;54(3):286-299
Journal of periodontal research 2019 Jun;54(3):286-299
Effects of 3-dimensional Bioprinting Alginate/Gelatin Hydrogel Scaffold Extract on Proliferation and Differentiation of Human Dental Pulp Stem Cells.
Yu H, Zhang X, Song W, Pan T, Wang H, Ning T, Wei Q, Xu HHK, Wu B, Ma D
Journal of endodontics 2019 Jun;45(6):706-715
Journal of endodontics 2019 Jun;45(6):706-715
The circRNA circPTPRA suppresses epithelial-mesenchymal transitioning and metastasis of NSCLC cells by sponging miR-96-5p.
Wei S, Zheng Y, Jiang Y, Li X, Geng J, Shen Y, Li Q, Wang X, Zhao C, Chen Y, Qian Z, Zhou J, Li W
EBioMedicine 2019 Jun;44:182-193
EBioMedicine 2019 Jun;44:182-193
FasL on decidual macrophages mediates trophoblast apoptosis: A potential cause of recurrent miscarriage.
Ding J, Yin T, Yan N, Cheng Y, Yang J
International journal of molecular medicine 2019 Jun;43(6):2376-2386
International journal of molecular medicine 2019 Jun;43(6):2376-2386
Obesity-associated family with sequence similarity 13, member A (FAM13A) is dispensable for adipose development and insulin sensitivity.
Tang J, Zhou H, Sahay K, Xu W, Yang J, Zhang W, Chen W
International journal of obesity (2005) 2019 Jun;43(6):1269-1280
International journal of obesity (2005) 2019 Jun;43(6):1269-1280
Probenecid Relieves Cerebral Dysfunction of Sepsis by Inhibiting Pannexin 1-Dependent ATP Release.
Zhang Z, Lei Y, Yan C, Mei X, Jiang T, Ma Z, Wang Q
Inflammation 2019 Jun;42(3):1082-1092
Inflammation 2019 Jun;42(3):1082-1092
Early Pattern of Epstein-Barr Virus Infection in Gastric Epithelial Cells by "Cell-in-cell".
Yue W, Zhu M, Zuo L, Xin S, Zhang J, Liu L, Li S, Dang W, Zhang S, Xie Y, Zhu F, Lu J
Virologica Sinica 2019 Jun;34(3):253-261
Virologica Sinica 2019 Jun;34(3):253-261
Reduced asymmetric dimethylarginine accumulation through inhibition of the type I protein arginine methyltransferases promotes renal fibrosis in obstructed kidneys.
Wu M, Lin P, Li L, Chen D, Yang X, Xu L, Zhou B, Wang C, Zhang Y, Luo C, Ye C
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 Jun;33(6):6948-6956
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 Jun;33(6):6948-6956
Suppression of puerarin on polymethylmethacrylate-induced lesion of peri-implant by inhibiting NF-κB activation in vitro and in vivo.
Yan B, Zhou H, Chu J, Cao X
Pathology, research and practice 2019 Jun;215(6):152372
Pathology, research and practice 2019 Jun;215(6):152372
An SOD1 deficiency aggravates proteasome inhibitor bortezomib-induced testicular damage in mice.
Homma T, Fujii J
Biochimica et biophysica acta. General subjects 2019 Jun;1863(6):1108-1115
Biochimica et biophysica acta. General subjects 2019 Jun;1863(6):1108-1115
The p53/miRNAs/Ccna2 pathway serves as a novel regulator of cellular senescence: Complement of the canonical p53/p21 pathway.
Xu S, Wu W, Huang H, Huang R, Xie L, Su A, Liu S, Zheng R, Yuan Y, Zheng HL, Sun X, Xiong XD, Liu X
Aging cell 2019 Jun;18(3):e12918
Aging cell 2019 Jun;18(3):e12918
Enhanced responsiveness of platelets to vicagrel in IL-10-deficient mice through STAT3-dependent up-regulation of the hydrolase arylacetamide deacetylase in the intestine.
Jia YM, Zhou H, Tai T, Gu TT, Ji JZ, Mi QY, Huang BB, Li YF, Zhu T, Xie HG
British journal of pharmacology 2019 Jun;176(11):1717-1727
British journal of pharmacology 2019 Jun;176(11):1717-1727
Inhibition of Wee1 sensitizes AML cells to ATR inhibitor VE-822-induced DNA damage and apoptosis.
Qi W, Xu X, Wang M, Li X, Wang C, Sun L, Zhao D, Sun L
Biochemical pharmacology 2019 Jun;164:273-282
Biochemical pharmacology 2019 Jun;164:273-282
AC002454.1 and CDK6 synergistically promote endometrial cell migration and invasion in endometriosis.
Liu J, Wang Y, Chen P, Ma Y, Wang S, Tian Y, Wang A, Wang D
Reproduction (Cambridge, England) 2019 Jun;157(6):535-543
Reproduction (Cambridge, England) 2019 Jun;157(6):535-543
Hydrogen sulfide protects against DSS-induced colitis by inhibiting NLRP3 inflammasome.
Qin M, Long F, Wu W, Yang D, Huang M, Xiao C, Chen X, Liu X, Zhu YZ
Free radical biology & medicine 2019 Jun;137:99-109
Free radical biology & medicine 2019 Jun;137:99-109
Amplification of USP13 drives non-small cell lung cancer progression mediated by AKT/MAPK signaling.
Wu Y, Zhang Y, Liu C, Zhang Y, Wang D, Wang S, Wu Y, Liu F, Li Q, Liu X, Zaky MY, Yan D, Liu S
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Jun;114:108831
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Jun;114:108831
Antithrombotic Effect of shRNA Target F12 Mediated by Adeno-Associated Virus.
Li F, Yang X, Liu J, Shu K, Shen C, Chen T, Yang W, Li S, Wang X, Jiang M
Molecular therapy. Nucleic acids 2019 Jun 7;16:295-301
Molecular therapy. Nucleic acids 2019 Jun 7;16:295-301
Insulin-like growth factor-1 attenuates oxidative stress-induced hepatocyte premature senescence in liver fibrogenesis via regulating nuclear p53-progerin interaction.
Luo X, Jiang X, Li J, Bai Y, Li Z, Wei P, Sun S, Liang Y, Han S, Li X, Zhang B
Cell death & disease 2019 Jun 6;10(6):451
Cell death & disease 2019 Jun 6;10(6):451
Death-associated protein kinase 3 deficiency alleviates vascular calcification via AMPK-mediated inhibition of endoplasmic reticulum stress.
Li KX, Du Q, Wang HP, Sun HJ
European journal of pharmacology 2019 Jun 5;852:90-98
European journal of pharmacology 2019 Jun 5;852:90-98
Alternative transcription start site selection in ACSS2 controls its nuclear localization and promotes ribosome biosynthesis in hepatocellular carcinoma.
Wang YH, Huang S, Zhu L, Yang Q, Yang XM, Gu JR, Zhang ZG, Nie HZ, Li J
Biochemical and biophysical research communications 2019 Jun 30;514(3):632-638
Biochemical and biophysical research communications 2019 Jun 30;514(3):632-638
NLRC5 inhibits neointima formation following vascular injury and directly interacts with PPARγ.
Luan P, Jian W, Xu X, Kou W, Yu Q, Hu H, Li D, Wang W, Feinberg MW, Zhuang J, Xu Y, Peng W
Nature communications 2019 Jun 28;10(1):2882
Nature communications 2019 Jun 28;10(1):2882
Pervasive Chromatin-RNA Binding Protein Interactions Enable RNA-Based Regulation of Transcription.
Xiao R, Chen JY, Liang Z, Luo D, Chen G, Lu ZJ, Chen Y, Zhou B, Li H, Du X, Yang Y, San M, Wei X, Liu W, Lécuyer E, Graveley BR, Yeo GW, Burge CB, Zhang MQ, Zhou Y, Fu XD
Cell 2019 Jun 27;178(1):107-121.e18
Cell 2019 Jun 27;178(1):107-121.e18
Transcriptional Regulation of gga-miR-451 by AhR:Arnt in Mycoplasma gallisepticum (HS Strain) Infection.
Zhao Y, Fu Y, Sun Y, Zou M, Peng X
International journal of molecular sciences 2019 Jun 24;20(12)
International journal of molecular sciences 2019 Jun 24;20(12)
miR-211 facilitates platinum chemosensitivity by blocking the DNA damage response (DDR) in ovarian cancer.
Wang T, Hao D, Yang S, Ma J, Yang W, Zhu Y, Weng M, An X, Wang X, Li Y, Wu D, Tang J, Yang C, He Y, Zhang L, Jin X, Wang G, Li Z, Zheng T, Meng H, Feng Y, Li X
Cell death & disease 2019 Jun 24;10(7):495
Cell death & disease 2019 Jun 24;10(7):495
Identification of metabolic vulnerabilities of receptor tyrosine kinases-driven cancer.
Jin N, Bi A, Lan X, Xu J, Wang X, Liu Y, Wang T, Tang S, Zeng H, Chen Z, Tan M, Ai J, Xie H, Zhang T, Liu D, Huang R, Song Y, Leung EL, Yao X, Ding J, Geng M, Lin SH, Huang M
Nature communications 2019 Jun 20;10(1):2701
Nature communications 2019 Jun 20;10(1):2701
Quercetin inhibits kidney fibrosis and the epithelial to mesenchymal transition of the renal tubular system involving suppression of the Sonic Hedgehog signaling pathway.
Liu X, Sun N, Mo N, Lu S, Song E, Ren C, Li Z
Food & function 2019 Jun 19;10(6):3782-3797
Food & function 2019 Jun 19;10(6):3782-3797
Low Polymerase Activity Attributed to PA Drives the Acquisition of the PB2 E627K Mutation of H7N9 Avian Influenza Virus in Mammals.
Liang L, Jiang L, Li J, Zhao Q, Wang J, He X, Huang S, Wang Q, Zhao Y, Wang G, Sun N, Deng G, Shi J, Tian G, Zeng X, Jiang Y, Liu L, Liu J, Chen P, Bu Z, Kawaoka Y, Chen H, Li C
mBio 2019 Jun 18;10(3)
mBio 2019 Jun 18;10(3)
Induction of Fibrosis and Autophagy in Kidney Cells by Vinyl Chloride.
Hsu YH, Chuang HC, Lee YH, Lin YF, Chiu YJ, Wang YL, Wu MS, Chiu HW
Cells 2019 Jun 17;8(6)
Cells 2019 Jun 17;8(6)
Cellular Interleukin Enhancer-Binding Factor 2, ILF2, Inhibits Japanese Encephalitis Virus Replication In Vitro.
Cui X, Qian P, Rao T, Wei Y, Zhao F, Zhang H, Chen H, Li X
Viruses 2019 Jun 17;11(6)
Viruses 2019 Jun 17;11(6)
Insulin transcriptionally down-regulates carboxylesterases through pregnane X receptor in an Akt-dependent manner.
Yang X, Zhang X, Liu Y, Xi T, Xiong J
Toxicology 2019 Jun 15;422:60-68
Toxicology 2019 Jun 15;422:60-68
NOL12 Repression Induces Nucleolar Stress-Driven Cellular Senescence and Is Associated with Normative Aging.
Pinho M, Macedo JC, Logarinho E, Pereira PS
Molecular and cellular biology 2019 Jun 15;39(12)
Molecular and cellular biology 2019 Jun 15;39(12)
Dihydromyricetin alleviates acetaminophen-induced liver injury via the regulation of transformation, lipid homeostasis, cell death and regeneration.
Dong S, Ji J, Hu L, Wang H
Life sciences 2019 Jun 15;227:20-29
Life sciences 2019 Jun 15;227:20-29
Fine particulate matter-induced cardiovascular injury is associated with NLRP3 inflammasome activation in Apo E(-/-) mice.
Du X, Jiang S, Zeng X, Zhang J, Pan K, Song L, Zhou J, Kan H, Sun Q, Zhao J, Xie Y
Ecotoxicology and environmental safety 2019 Jun 15;174:92-99
Ecotoxicology and environmental safety 2019 Jun 15;174:92-99
Heartland virus antagonizes type I and III interferon antiviral signaling by inhibiting phosphorylation and nuclear translocation of STAT2 and STAT1.
Feng K, Deng F, Hu Z, Wang H, Ning YJ
The Journal of biological chemistry 2019 Jun 14;294(24):9503-9517
The Journal of biological chemistry 2019 Jun 14;294(24):9503-9517
Small molecule inhibitor of TGF-β signaling enables robust osteogenesis of autologous GMSCs to successfully repair minipig severe maxillofacial bone defects.
Shi A, Heinayati A, Bao D, Liu H, Ding X, Tong X, Wang L, Wang B, Qin H
Stem cell research & therapy 2019 Jun 13;10(1):172
Stem cell research & therapy 2019 Jun 13;10(1):172
CDK9 modulates circadian clock by attenuating REV-ERBα activity.
Ou J, Li H, Qiu P, Li Q, Chang HC, Tang YC
Biochemical and biophysical research communications 2019 Jun 11;513(4):967-973
Biochemical and biophysical research communications 2019 Jun 11;513(4):967-973
Arsenic trioxide inhibits EMT in hepatocellular carcinoma by promoting lncRNA MEG3 via PKM2.
Fan Z, He J, Fu T, Zhang W, Yang G, Qu X, Liu R, Lv L, Wang J
Biochemical and biophysical research communications 2019 Jun 11;513(4):834-840
Biochemical and biophysical research communications 2019 Jun 11;513(4):834-840
Targeting ATGL to rescue BSCL2 lipodystrophy and its associated cardiomyopathy.
Zhou H, Lei X, Yan Y, Lydic T, Li J, Weintraub NL, Su H, Chen W
JCI insight 2019 Jun 11;5(14)
JCI insight 2019 Jun 11;5(14)
microRNA-378a Regulates the Reactive Oxygen Species (ROS)/Phosphatidylinositol 3-Kinases (PI3K)/AKT Signaling Pathway in Human Lens Epithelial Cells and Cataract.
Liu Y, Li H, Liu Y
Medical science monitor : international medical journal of experimental and clinical research 2019 Jun 10;25:4314-4321
Medical science monitor : international medical journal of experimental and clinical research 2019 Jun 10;25:4314-4321
Role of TMPRSS4 Modulation in Breast Cancer Cell Proliferation.
Assani G, Yessoufou A, Xiong Y, Segbo J, Yu X, Zhou F, Zhou Y
Asian Pacific journal of cancer prevention : APJCP 2019 Jun 1;20(6):1849-1856
Asian Pacific journal of cancer prevention : APJCP 2019 Jun 1;20(6):1849-1856
Nrf2 deficiency aggravates Angiotensin II-induced cardiac injury by increasing hypertrophy and enhancing IL-6/STAT3-dependent inflammation.
Chen D, Li Z, Bao P, Chen M, Zhang M, Yan F, Xu Y, Ji C, Hu X, Sanchis D, Zhang Y, Ye J
Biochimica et biophysica acta. Molecular basis of disease 2019 Jun 1;1865(6):1253-1264
Biochimica et biophysica acta. Molecular basis of disease 2019 Jun 1;1865(6):1253-1264
Aerobic exercise regulates synaptic transmission and reactive oxygen species production in the paraventricular nucleus of spontaneously hypertensive rats.
Li C, Li Y, Zhao Z, Lv Y, Gu B, Zhao L
Brain research 2019 Jun 1;1712:82-92
Brain research 2019 Jun 1;1712:82-92
Esrrb plays important roles in maintaining self-renewal of trophoblast stem cells (TSCs) and reprogramming somatic cells to induced TSCs.
Gao H, Gao R, Zhang L, Xiu W, Zang R, Wang H, Zhang Y, Chen J, Gao Y, Gao S
Journal of molecular cell biology 2019 Jun 1;11(6):463-473
Journal of molecular cell biology 2019 Jun 1;11(6):463-473
Cardamonin from a medicinal herb protects against LPS-induced septic shock by suppressing NLRP3 inflammasome.
Wang Z, Xu G, Gao Y, Zhan X, Qin N, Fu S, Li R, Niu M, Wang J, Liu Y, Xiao X, Bai Z
Acta pharmaceutica Sinica. B 2019 Jul;9(4):734-744
Acta pharmaceutica Sinica. B 2019 Jul;9(4):734-744
IL-25 promotes cisplatin resistance of lung cancer cells by activating NF-κB signaling pathway to increase of major vault protein.
Shen W, Qiu Y, Li J, Wu C, Liu Z, Zhang X, Hu X, Liao Y, Wang H
Cancer medicine 2019 Jul;8(7):3491-3501
Cancer medicine 2019 Jul;8(7):3491-3501
Anti-inflammatory and antitumour activity of various extracts and compounds from the fruits of Piper longum L.
Guo Z, Xu J, Xia J, Wu Z, Lei J, Yu J
The Journal of pharmacy and pharmacology 2019 Jul;71(7):1162-1171
The Journal of pharmacy and pharmacology 2019 Jul;71(7):1162-1171
Knockdown of circulating C1 inhibitor induces neurovascular impairment, glial cell activation, neuroinflammation, and behavioral deficits.
Farfara D, Feierman E, Richards A, Revenko AS, MacLeod RA, Norris EH, Strickland S
Glia 2019 Jul;67(7):1359-1373
Glia 2019 Jul;67(7):1359-1373
MicroRNA-135b alleviates MPP(+)-mediated Parkinson's disease in in vitro model through suppressing FoxO1-induced NLRP3 inflammasome and pyroptosis.
Zeng R, Luo DX, Li HP, Zhang QS, Lei SS, Chen JH
Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 2019 Jul;65:125-133
Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 2019 Jul;65:125-133
APS could potentially activate hepatic insulin signaling in HFD-induced IR mice.
Sun J, Liu Y, Yu J, Wu J, Gao W, Ran L, Jiang R, Guo M, Han D, Liu B, Wang N, Li Y, Huang H, Zeng L, Gao Y, Li X, Wu Y
Journal of molecular endocrinology 2019 Jul;63(1):77-91
Journal of molecular endocrinology 2019 Jul;63(1):77-91
MicroRNA-221 sensitizes chronic myeloid leukemia cells to imatinib by targeting STAT5.
Jiang X, Cheng Y, Hu C, Zhang A, Ren Y, Xu X
Leukemia & lymphoma 2019 Jul;60(7):1709-1720
Leukemia & lymphoma 2019 Jul;60(7):1709-1720
Comparison of intracellular responses between HBV genotype A and C infection in human hepatocyte chimeric mice.
Tsushima K, Tsuge M, Hiraga N, Uchida T, Murakami E, Makokha GN, Kurihara M, Nomura M, Hiyama Y, Fujino H, Ono A, Nakahara T, Yamauchi M, Abe-Chayama H, Kawaoka T, Miki D, Imamura M, Aikata H, Hayes CN, Chayama K
Journal of gastroenterology 2019 Jul;54(7):650-659
Journal of gastroenterology 2019 Jul;54(7):650-659
Clearance of apoptotic cells by mesenchymal stem cells contributes to immunosuppression via PGE2.
Zhang Z, Huang S, Wu S, Qi J, Li W, Liu S, Cong Y, Chen H, Lu L, Shi S, Wang D, Chen W, Sun L
EBioMedicine 2019 Jul;45:341-350
EBioMedicine 2019 Jul;45:341-350
The potential role of pregnancy-associated plasma protein-A2 in angiogenesis and development of preeclampsia.
Chen X, Chen K, Feng Y, Ren C, Li W, Xiao J, Fan L, Beejadhursing R, Xi L, Chen S
Hypertension research : official journal of the Japanese Society of Hypertension 2019 Jul;42(7):970-980
Hypertension research : official journal of the Japanese Society of Hypertension 2019 Jul;42(7):970-980
Luteolin suppresses colorectal cancer cell metastasis via regulation of the miR‑384/pleiotrophin axis.
Yao Y, Rao C, Zheng G, Wang S
Oncology reports 2019 Jul;42(1):131-141
Oncology reports 2019 Jul;42(1):131-141
Dynasore Suppresses mTORC1 Activity and Induces Autophagy to Regulate the Clearance of Protein Aggregates in Neurodegenerative Diseases.
Chen Y, Xu S, Wang N, Ma Q, Peng P, Yu Y, Zhang L, Ying Z, Wang H
Neurotoxicity research 2019 Jul;36(1):108-116
Neurotoxicity research 2019 Jul;36(1):108-116
Reduction of PGRN increased fibrosis during skin wound healing in mice.
Li SS, Zhang MX, Wang Y, Wang W, Zhao CM, Sun XM, Dong GK, Li ZR, Yin WJ, Zhu B, Cai HX
Histology and histopathology 2019 Jul;34(7):765-774
Histology and histopathology 2019 Jul;34(7):765-774
Activation of prostaglandin EP4 receptor attenuates the induction of cyclooxygenase-2 expression by EP2 receptor activation in human amnion fibroblasts: implications for parturition.
Lu JW, Wang WS, Zhou Q, Gan XW, Myatt L, Sun K
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 Jul;33(7):8148-8160
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 Jul;33(7):8148-8160
Resveratrol targets TyrRS acetylation to protect against radiation-induced damage.
Gao P, Li N, Ji K, Wang Y, Xu C, Liu Y, Wang Q, Wang J, He N, Sun Z, Du L, Liu Q
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 Jul;33(7):8083-8093
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 Jul;33(7):8083-8093
Notch signaling activation induces cell death in MAPKi-resistant melanoma cells.
Mikheil DM, Prabhakar K, Arshad A, Rodriguez CI, Newton MA, Setaluri V
Pigment cell & melanoma research 2019 Jul;32(4):528-539
Pigment cell & melanoma research 2019 Jul;32(4):528-539
Molecular basis of vasohibins-mediated detyrosination and its impact on spindle function and mitosis.
Liao S, Rajendraprasad G, Wang N, Eibes S, Gao J, Yu H, Wu G, Tu X, Huang H, Barisic M, Xu C
Cell research 2019 Jul;29(7):533-547
Cell research 2019 Jul;29(7):533-547
Alcohol dehydrogenase of Candida albicans triggers differentiation of THP-1 cells into macrophages.
Liu Y, Ou Y, Sun L, Li W, Yang J, Zhang X, Hu Y
Journal of advanced research 2019 Jul;18:137-145
Journal of advanced research 2019 Jul;18:137-145
Neuroprotection of Fasting Mimicking Diet on MPTP-Induced Parkinson's Disease Mice via Gut Microbiota and Metabolites.
Zhou ZL, Jia XB, Sun MF, Zhu YL, Qiao CM, Zhang BP, Zhao LP, Yang Q, Cui C, Chen X, Shen YQ
Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics 2019 Jul;16(3):741-760
Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics 2019 Jul;16(3):741-760
Harnessing the anti-cancer natural product nimbolide for targeted protein degradation.
Spradlin JN, Hu X, Ward CC, Brittain SM, Jones MD, Ou L, To M, Proudfoot A, Ornelas E, Woldegiorgis M, Olzmann JA, Bussiere DE, Thomas JR, Tallarico JA, McKenna JM, Schirle M, Maimone TJ, Nomura DK
Nature chemical biology 2019 Jul;15(7):747-755
Nature chemical biology 2019 Jul;15(7):747-755
RTN1-C is involved in high glucose-aggravated neuronal cell subjected to oxygen-glucose deprivation and reoxygenation injury via endoplasmic reticulum stress.
Lin M, Ling J, Geng X, Zhang J, Du J, Chen L
Brain research bulletin 2019 Jul;149:129-136
Brain research bulletin 2019 Jul;149:129-136
Long-term pulmonary exposure to multi-walled carbon nanotubes promotes breast cancer metastatic cascades.
Lu X, Zhu Y, Bai R, Wu Z, Qian W, Yang L, Cai R, Yan H, Li T, Pandey V, Liu Y, Lobie PE, Chen C, Zhu T
Nature nanotechnology 2019 Jul;14(7):719-727
Nature nanotechnology 2019 Jul;14(7):719-727
Aqueous extract of Salvia miltiorrhiza Bunge-Radix Puerariae herb pair ameliorates diabetic vascular injury by inhibiting oxidative stress in streptozotocin-induced diabetic rats.
Zhao W, Yuan Y, Zhao H, Han Y, Chen X
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2019 Jul;129:97-107
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2019 Jul;129:97-107
Effect of Hypoxia on the Muscle Fiber Switching Signal Pathways CnA/NFATc1 and Myostatin in Mouse Myocytes.
Lixin L, Juan W, Yun B, Jingwei L, Xiuju Y, Xiaomao L, Zhiwei Z, Xiaoyan H, Yanjun D, Hongquan L, Haidong W
Acta histochemica 2019 Jul;121(5):539-545
Acta histochemica 2019 Jul;121(5):539-545
Hsa_circ_0023404 enhances cervical cancer metastasis and chemoresistance through VEGFA and autophagy signaling by sponging miR-5047.
Guo J, Chen M, Ai G, Mao W, Li H, Zhou J
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Jul;115:108957
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Jul;115:108957
Taurine protects against arsenic trioxide-induced insulin resistance via ROS-Autophagy pathway in skeletal muscle.
Yang L, Qiu T, Yao X, Jiang L, Wei S, Pei P, Wang Z, Bai J, Liu X, Yang G, Liu S, Sun X
The international journal of biochemistry & cell biology 2019 Jul;112:50-60
The international journal of biochemistry & cell biology 2019 Jul;112:50-60
Long noncoding RNA actin filament-associated protein 1 antisense RNA 1 promotes malignant phenotype through binding with lysine-specific demethylase 1 and repressing HMG box-containing protein 1 in non-small-cell lung cancer.
Yu S, Yang D, Ye Y, Liu P, Chen Z, Lei T, Pu J, Liu L, Wang Z
Cancer science 2019 Jul;110(7):2211-2225
Cancer science 2019 Jul;110(7):2211-2225
Lysine glutarylation in human sperm is associated with progressive motility.
Cheng YM, Hu XN, Peng Z, Pan TT, Wang F, Chen HY, Chen WQ, Zhang Y, Zeng XH, Luo T
Human reproduction (Oxford, England) 2019 Jul 8;34(7):1186-1194
Human reproduction (Oxford, England) 2019 Jul 8;34(7):1186-1194
microRNA-16-5p promotes 3T3-L1 adipocyte differentiation through regulating EPT1.
Xu J, Zhang L, Shu G, Wang B
Biochemical and biophysical research communications 2019 Jul 5;514(4):1251-1256
Biochemical and biophysical research communications 2019 Jul 5;514(4):1251-1256
Comparative interactome analysis reveals distinct and overlapping properties of Raf family kinases.
Zhang XY, Guo H, Huang Y, Hao PQ, Yang Y, Liu Y, Guo XX, Hao Q, An S, Xu TR
Biochemical and biophysical research communications 2019 Jul 5;514(4):1217-1223
Biochemical and biophysical research communications 2019 Jul 5;514(4):1217-1223
Long noncoding RNA PCAT1, a novel serum-based biomarker, enhances cell growth by sponging miR-326 in oesophageal squamous cell carcinoma.
Huang L, Wang Y, Chen J, Wang Y, Zhao Y, Wang Y, Ma Y, Chen X, Liu W, Li Z, Zhao L, Shan B, Dong X, Li D, Shao S, Song Y, Zhan Q, Liu X
Cell death & disease 2019 Jul 4;10(7):513
Cell death & disease 2019 Jul 4;10(7):513
TSPAN12 Precedes Tumor Proliferation by Cell Cycle Control in Ovarian Cancer.
Ji G, Liang H, Wang F, Wang N, Fu S, Cui X
Molecules and cells 2019 Jul 31;42(7):557-567
Molecules and cells 2019 Jul 31;42(7):557-567
LncRNA-H19 promotes hepatic lipogenesis by directly regulating miR-130a/PPARγ axis in non-alcoholic fatty liver disease.
Liu J, Tang T, Wang GD, Liu B
Bioscience reports 2019 Jul 31;39(7)
Bioscience reports 2019 Jul 31;39(7)
A novel RP2 missense mutation Q158P identified in an X-linked retinitis pigmentosa family impaired RP2 protein stability.
Zhang J, Gao F, Du C, Wang J, Pi X, Guo W, Li J, Li H, Ma Y, Zhang W, Mu H, Hu Y, Cui X
Gene 2019 Jul 30;707:86-92
Gene 2019 Jul 30;707:86-92
Melatonin attenuates cadmium-induced ovulatory dysfunction by suppressing endoplasmic reticulum stress and cell apoptosis.
Yang Q, Zhu J, Luo X, Li F, Cong L, Wang Y, Sun Y
Reproductive biology and endocrinology : RB&E 2019 Jul 29;17(1):61
Reproductive biology and endocrinology : RB&E 2019 Jul 29;17(1):61
MiR-205 mediated APC regulation contributes to pancreatic cancer cell proliferation.
Qin RF, Zhang J, Huo HR, Yuan ZJ, Xue JD
World journal of gastroenterology 2019 Jul 28;25(28):3775-3786
World journal of gastroenterology 2019 Jul 28;25(28):3775-3786
Osteoprotegerin (OPG) Promotes Recruitment of Endothelial Progenitor Cells (EPCs) via CXCR4 Signaling Pathway to Improve Bone Defect Repair.
Zhang R, Liu J, Yu S, Sun D, Wang X, Fu J, Shen J, Xie Z
Medical science monitor : international medical journal of experimental and clinical research 2019 Jul 27;25:5572-5579
Medical science monitor : international medical journal of experimental and clinical research 2019 Jul 27;25:5572-5579
Simultaneous knockdown of YAP and TAZ increases apoptosis of hepatocellular carcinoma cells under hypoxic condition.
Yan B, Li T, Shen L, Zhou Z, Liu X, Wang X, Sun X
Biochemical and biophysical research communications 2019 Jul 23;515(2):275-281
Biochemical and biophysical research communications 2019 Jul 23;515(2):275-281
Diallyl Disulfide Induces Apoptosis and Autophagy in Human Osteosarcoma MG-63 Cells through the PI3K/Akt/mTOR Pathway.
Yue Z, Guan X, Chao R, Huang C, Li D, Yang P, Liu S, Hasegawa T, Guo J, Li M
Molecules (Basel, Switzerland) 2019 Jul 23;24(14)
Molecules (Basel, Switzerland) 2019 Jul 23;24(14)
Blood autophagy defect causes accelerated non-hematopoietic organ aging.
Fang Y, Zhu L, An N, Jiang G, Qian J, Zhao R, Yuan N, Zhang S, Wang J
Aging 2019 Jul 21;11(14):4910-4922
Aging 2019 Jul 21;11(14):4910-4922
Inhibitory Effects of Oxymatrine on Transdifferentiation of Neonatal Rat Cardiac Fibroblasts to Myofibroblasts Induced by Aldosterone via Keap1/Nrf2 Signaling Pathways In Vitro.
Yang Y, Chen S, Tao L, Gan S, Luo H, Xu Y, Shen X
Medical science monitor : international medical journal of experimental and clinical research 2019 Jul 20;25:5375-5388
Medical science monitor : international medical journal of experimental and clinical research 2019 Jul 20;25:5375-5388
SFRS11 Loss Leads to Aging-Associated Cognitive Decline by Modulating LRP8 and ApoE.
Raihan O, Brishti A, Li Q, Zhang Q, Li D, Li X, Zhang Q, Xie Z, Li J, Zhang J, Liu Q
Cell reports 2019 Jul 2;28(1):78-90.e6
Cell reports 2019 Jul 2;28(1):78-90.e6
Structural and functional analyses of hepatitis B virus X protein BH3-like domain and Bcl-xL interaction.
Zhang TY, Chen HY, Cao JL, Xiong HL, Mo XB, Li TL, Kang XZ, Zhao JH, Yin B, Zhao X, Huang CH, Yuan Q, Xue D, Xia NS, Yuan YA
Nature communications 2019 Jul 19;10(1):3192
Nature communications 2019 Jul 19;10(1):3192
CD4 Expression and Env Conformation Are Critical for HIV-1 Restriction by SERINC5.
Zhang X, Shi J, Qiu X, Chai Q, Frabutt DA, Schwartz RC, Zheng YH
Journal of virology 2019 Jul 15;93(14)
Journal of virology 2019 Jul 15;93(14)
A novel, highly-water-soluble apigenin derivative provides neuroprotection following ischemia in male rats by regulating the ERK/Nrf2/HO-1 pathway.
Zhang S, Xu S, Duan H, Zhu Z, Yang Z, Cao J, Zhao Y, Huang Z, Wu Q, Duan J
European journal of pharmacology 2019 Jul 15;855:208-215
European journal of pharmacology 2019 Jul 15;855:208-215
LncRNA FOXD2-AS1 plays an oncogenic role in hepatocellular carcinoma through epigenetically silencing CDKN1B(p27) via EZH2.
Xu K, Zhang Z, Qian J, Wang S, Yin S, Xie H, Zhou L, Zheng S
Experimental cell research 2019 Jul 15;380(2):198-204
Experimental cell research 2019 Jul 15;380(2):198-204
Matrine inhibits IL-1β secretion in primary porcine alveolar macrophages through the MyD88/NF-κB pathway and NLRP3 inflammasome.
Sun P, Sun N, Yin W, Sun Y, Fan K, Guo J, Khan A, He Y, Li H
Veterinary research 2019 Jul 12;50(1):53
Veterinary research 2019 Jul 12;50(1):53
KHDRBS3 regulates the permeability of blood-tumor barrier via cDENND4C/miR-577 axis.
Wu P, Gao Y, Shen S, Xue Y, Liu X, Ruan X, Shao L, Liu Y, Wang P
Cell death & disease 2019 Jul 11;10(7):536
Cell death & disease 2019 Jul 11;10(7):536
Insulin-like growth factor 2 mRNA binding protein 2 promotes aerobic glycolysis and cell proliferation in pancreatic ductal adenocarcinoma via stabilizing GLUT1 mRNA.
Huang S, Wu Z, Cheng Y, Wei W, Hao L
Acta biochimica et biophysica Sinica 2019 Jul 10;51(7):743-752
Acta biochimica et biophysica Sinica 2019 Jul 10;51(7):743-752
Knockdown ATG4C inhibits gliomas progression and promotes temozolomide chemosensitivity by suppressing autophagic flux.
Wen ZP, Zeng WJ, Chen YH, Li H, Wang JY, Cheng Q, Yu J, Zhou HH, Liu ZZ, Xiao J, Chen XP
Journal of experimental & clinical cancer research : CR 2019 Jul 10;38(1):298
Journal of experimental & clinical cancer research : CR 2019 Jul 10;38(1):298
Activation of 20-HETE/PPARs involved in reno-therapeutic effect of naringenin on diabetic nephropathy.
Ding S, Qiu H, Huang J, Chen R, Zhang J, Huang B, Zou X, Cheng O, Jiang Q
Chemico-biological interactions 2019 Jul 1;307:116-124
Chemico-biological interactions 2019 Jul 1;307:116-124
Toxicological exploration of peptide-based cationic liposomes in siRNA delivery.
Zhu Y, Meng Y, Zhao Y, Zhu J, Xu H, Zhang E, Shi L, Du L, Liu G, Zhang C, Xu X, Kang X, Zhen Y, Zhang S
Colloids and surfaces. B, Biointerfaces 2019 Jul 1;179:66-76
Colloids and surfaces. B, Biointerfaces 2019 Jul 1;179:66-76
Exosomal miR-1229 derived from colorectal cancer cells promotes angiogenesis by targeting HIPK2.
Hu HY, Yu CH, Zhang HH, Zhang SZ, Yu WY, Yang Y, Chen Q
International journal of biological macromolecules 2019 Jul 1;132:470-477
International journal of biological macromolecules 2019 Jul 1;132:470-477
Phenylephrine Alleviates (131)I Radiation Damage in Submandibular Gland Through Maintaining Mitochondrial Homeostasis.
Wang XY, Yu J, Zhang FY, Liu KJ, Xiang B
International journal of radiation oncology, biology, physics 2019 Jul 1;104(3):644-655
International journal of radiation oncology, biology, physics 2019 Jul 1;104(3):644-655
Extracellular matrix remodeling effects of serum amyloid A1 in the human amnion: Implications for fetal membrane rupture.
Wang YW, Wang WS, Wang LY, Bao YR, Lu JW, Lu Y, Zhang CY, Li WJ, Sun K, Ying H
American journal of reproductive immunology (New York, N.Y. : 1989) 2019 Jan;81(1):e13073
American journal of reproductive immunology (New York, N.Y. : 1989) 2019 Jan;81(1):e13073
Overexpression of P2X4 receptor in Schwann cells promotes motor and sensory functional recovery and remyelination via BDNF secretion after nerve injury.
Su WF, Wu F, Jin ZH, Gu Y, Chen YT, Fei Y, Chen H, Wang YX, Xing LY, Zhao YY, Yuan Y, Tang X, Chen G
Glia 2019 Jan;67(1):78-90
Glia 2019 Jan;67(1):78-90
Neuroprotective effects of Astilbin on MPTP-induced Parkinson's disease mice: Glial reaction, α-synuclein expression and oxidative stress.
Zhu YL, Sun MF, Jia XB, Cheng K, Xu YD, Zhou ZL, Zhang PH, Qiao CM, Cui C, Chen X, Yang XS, Shen YQ
International immunopharmacology 2019 Jan;66:19-27
International immunopharmacology 2019 Jan;66:19-27
BMAL1 knockout macaque monkeys display reduced sleep and psychiatric disorders.
Qiu P, Jiang J, Liu Z, Cai Y, Huang T, Wang Y, Liu Q, Nie Y, Liu F, Cheng J, Li Q, Tang YC, Poo MM, Sun Q, Chang HC
National science review 2019 Jan;6(1):87-100
National science review 2019 Jan;6(1):87-100
HUS1 checkpoint clamp component (HUS1) is a potential tumor suppressor in primary hepatocellular carcinoma.
Zhou ZQ, Zhao JJ, Chen CL, Liu Y, Zeng JX, Wu ZR, Tang Y, Zhu Q, Weng DS, Xia JC
Molecular carcinogenesis 2019 Jan;58(1):76-87
Molecular carcinogenesis 2019 Jan;58(1):76-87
ERp57‑small interfering RNA silencing can enhance the sensitivity of drug‑resistant human ovarian cancer cells to paclitaxel.
Li S, Zhao X, Chang S, Li Y, Guo M, Guan Y
International journal of oncology 2019 Jan;54(1):249-260
International journal of oncology 2019 Jan;54(1):249-260
MiR-20a Plays a Key Regulatory Role in the Repair of Spinal Cord Dorsal Column Lesion via PDZ-RhoGEF/RhoA/GAP43 Axis in Rat.
Wang T, Li B, Yuan X, Cui L, Wang Z, Zhang Y, Yu M, Xiu Y, Zhang Z, Li W, Wang F, Guo X, Zhao X, Chen X
Cellular and molecular neurobiology 2019 Jan;39(1):87-98
Cellular and molecular neurobiology 2019 Jan;39(1):87-98
Heme oxygenase-1 prevents heart against myocardial infarction by attenuating ischemic injury-induced cardiomyocytes senescence.
Shan H, Li T, Zhang L, Yang R, Li Y, Zhang M, Dong Y, Zhou Y, Xu C, Yang B, Liang H, Gao X, Shan H
EBioMedicine 2019 Jan;39:59-68
EBioMedicine 2019 Jan;39:59-68
DPSCs seeded in acellular nerve grafts processed by Myroilysin improve nerve regeneration.
Qiao W, Lu L, Wu G, An X, Li D, Guo J
Journal of biomaterials applications 2019 Jan;33(6):819-833
Journal of biomaterials applications 2019 Jan;33(6):819-833
Dual regulatory role of CCNA2 in modulating CDK6 and MET-mediated cell-cycle pathway and EMT progression is blocked by miR-381-3p in bladder cancer.
Li J, Ying Y, Xie H, Jin K, Yan H, Wang S, Xu M, Xu X, Wang X, Yang K, Zheng X, Xie L
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 Jan;33(1):1374-1388
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 Jan;33(1):1374-1388
Chromium(VI) promotes cell migration through targeting epithelial-mesenchymal transition in prostate cancer.
Zhang C, Cai K, Feng Q, Xu Y, Zhang Z
Toxicology letters 2019 Jan;300:10-17
Toxicology letters 2019 Jan;300:10-17
MiR-10b suppresses the growth and metastasis of colorectal cancer cell by targeting FGF13.
Song JJ, Li W
European review for medical and pharmacological sciences 2019 Jan;23(2):576-587
European review for medical and pharmacological sciences 2019 Jan;23(2):576-587
Characterization and proteomic profiling of pancreatic cancer-derived serum exosomes.
Jiao YJ, Jin DD, Jiang F, Liu JX, Qu LS, Ni WK, Liu ZX, Lu CH, Ni RZ, Zhu J, Xiao MB
Journal of cellular biochemistry 2019 Jan;120(1):988-999
Journal of cellular biochemistry 2019 Jan;120(1):988-999
Combined detection of estrogen and tumor markers is an important reference factor in the diagnosis and prognosis of lung cancer.
Bai Y, Shen W, Zhu M, Zhang L, Wei Y, Tang H, Zhao J
Journal of cellular biochemistry 2019 Jan;120(1):105-114
Journal of cellular biochemistry 2019 Jan;120(1):105-114
EETs/PPARs activation together mediates the preventive effect of naringenin in high glucose-induced cardiomyocyte hypertrophy.
Zhang J, Qiu H, Huang J, Ding S, Huang B, Zhou P, Jiang Q
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Jan;109:1498-1505
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Jan;109:1498-1505
Ginsenoside Rd contributes the attenuation of cardiac hypertrophy in vivo and in vitro.
Zhang N, An X, Lang P, Wang F, Xie Y
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Jan;109:1016-1023
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Jan;109:1016-1023
Role of bone morphogenetic protein-2/4 in astrocyte activation in neuropathic pain.
Yang L, Liu S, Wang Y
Molecular pain 2019 Jan-Dec;15:1744806919892100
Molecular pain 2019 Jan-Dec;15:1744806919892100
Zingerone Nanotetramer Strengthened the Polypharmacological Efficacy of Zingerone on Human Hepatoma Cell Lines.
Kung ML, Lin PY, Huang ST, Tai MH, Hsieh SL, Wu CC, Yeh BW, Wu WJ, Hsieh S
ACS applied materials & interfaces 2019 Jan 9;11(1):137-150
ACS applied materials & interfaces 2019 Jan 9;11(1):137-150
A scorpion venom peptide Ev37 restricts viral late entry by alkalizing acidic organelles.
Li F, Lang Y, Ji Z, Xia Z, Han Y, Cheng Y, Liu G, Sun F, Zhao Y, Gao M, Chen Z, Wu Y, Li W, Cao Z
The Journal of biological chemistry 2019 Jan 4;294(1):182-194
The Journal of biological chemistry 2019 Jan 4;294(1):182-194
The deregulation of STIM1 and store operative calcium entry impaired aortic smooth muscle cells contractility in aortic medial degeneration.
Hong J, Hu Z, Wu Q, Tang C, Hu J, Chen R, Li B, Wang Z
Bioscience reports 2019 Jan 31;39(1)
Bioscience reports 2019 Jan 31;39(1)
DDX19 Inhibits Type I Interferon Production by Disrupting TBK1-IKKε-IRF3 Interactions and Promoting TBK1 and IKKε Degradation.
Zhang K, Zhang Y, Xue J, Meng Q, Liu H, Bi C, Li C, Hu L, Yu H, Xiong T, Yang Y, Cui S, Bu Z, He X, Li J, Huang L, Weng C
Cell reports 2019 Jan 29;26(5):1258-1272.e4
Cell reports 2019 Jan 29;26(5):1258-1272.e4
Atoh1 Controls Primary Cilia Formation to Allow for SHH-Triggered Granule Neuron Progenitor Proliferation.
Chang CH, Zanini M, Shirvani H, Cheng JS, Yu H, Feng CH, Mercier AL, Hung SY, Forget A, Wang CH, Cigna SM, Lu IL, Chen WY, Leboucher S, Wang WJ, Ruat M, Spassky N, Tsai JW, Ayrault O
Developmental cell 2019 Jan 28;48(2):184-199.e5
Developmental cell 2019 Jan 28;48(2):184-199.e5
The Plk1 kinase negatively regulates the Hedgehog signaling pathway by phosphorylating Gli1.
Zhang T, Xin G, Jia M, Zhuang T, Zhu S, Zhang B, Wang G, Jiang Q, Zhang C
Journal of cell science 2019 Jan 22;132(2)
Journal of cell science 2019 Jan 22;132(2)
Acetaldehyde dehydrogenase 2 interactions with LDLR and AMPK regulate foam cell formation.
Zhong S, Li L, Zhang YL, Zhang L, Lu J, Guo S, Liang N, Ge J, Zhu M, Tao Y, Wu YC, Yin H
The Journal of clinical investigation 2019 Jan 2;129(1):252-267
The Journal of clinical investigation 2019 Jan 2;129(1):252-267
LncRNA SNHG12 inhibits miR-199a to upregulate SIRT1 to attenuate cerebral ischemia/reperfusion injury through activating AMPK signaling pathway.
Yin WL, Yin WG, Huang BS, Wu LX
Neuroscience letters 2019 Jan 18;690:188-195
Neuroscience letters 2019 Jan 18;690:188-195
Sphingosine 1 phosphate receptor-1 (S1P1) promotes tumor-associated regulatory T cell expansion: leading to poor survival in bladder cancer.
Liu YN, Zhang H, Zhang L, Cai TT, Huang DJ, He J, Ni HH, Zhou FJ, Zhang XS, Li J
Cell death & disease 2019 Jan 18;10(2):50
Cell death & disease 2019 Jan 18;10(2):50
Genome-wide CRISPR Analysis Identifies Substrate-Specific Conjugation Modules in ER-Associated Degradation.
Leto DE, Morgens DW, Zhang L, Walczak CP, Elias JE, Bassik MC, Kopito RR
Molecular cell 2019 Jan 17;73(2):377-389.e11
Molecular cell 2019 Jan 17;73(2):377-389.e11
Transfer of Extracellular Vesicle-Associated-RNAs Induces Drug Resistance in ALK-Translocated Lung Adenocarcinoma.
Kwok HH, Ning Z, Chong PW, Wan TS, Ng MH, Ho GYF, Ip MS, Lam DC
Cancers 2019 Jan 17;11(1)
Cancers 2019 Jan 17;11(1)
Cathepsin C promotes microglia M1 polarization and aggravates neuroinflammation via activation of Ca(2+)-dependent PKC/p38MAPK/NF-κB pathway.
Liu Q, Zhang Y, Liu S, Liu Y, Yang X, Liu G, Shimizu T, Ikenaka K, Fan K, Ma J
Journal of neuroinflammation 2019 Jan 16;16(1):10
Journal of neuroinflammation 2019 Jan 16;16(1):10
Hepatitis B e Antigen Inhibits NF-κB Activity by Interrupting K63-Linked Ubiquitination of NEMO.
Wang Y, Cui L, Yang G, Zhan J, Guo L, Chen Y, Fan C, Liu D, Guo D
Journal of virology 2019 Jan 15;93(2)
Journal of virology 2019 Jan 15;93(2)
Binding of cellular nucleolin with the viral core RNA G-quadruplex structure suppresses HCV replication.
Bian WX, Xie Y, Wang XN, Xu GH, Fu BS, Li S, Long G, Zhou X, Zhang XL
Nucleic acids research 2019 Jan 10;47(1):56-68
Nucleic acids research 2019 Jan 10;47(1):56-68
N6-methyladenosine modification and METTL3 modulate enterovirus 71 replication.
Hao H, Hao S, Chen H, Chen Z, Zhang Y, Wang J, Wang H, Zhang B, Qiu J, Deng F, Guan W
Nucleic acids research 2019 Jan 10;47(1):362-374
Nucleic acids research 2019 Jan 10;47(1):362-374
Histone Demethylase KDM4B Promotes DNA Damage by Activating Long Interspersed Nuclear Element-1.
Xiang Y, Yan K, Zheng Q, Ke H, Cheng J, Xiong W, Shi X, Wei L, Zhao M, Yang F, Wang P, Lu X, Fu L, Lu X, Li F
Cancer research 2019 Jan 1;79(1):86-98
Cancer research 2019 Jan 1;79(1):86-98
FAPP2 promotes tumor cell growth in human colon cancer through activation of Wnt signaling.
Chen J, Li L, Zhou Z, Yu S, Li Y, Gao Y
Experimental cell research 2019 Jan 1;374(1):12-18
Experimental cell research 2019 Jan 1;374(1):12-18
Piezo1 mediates angiogenesis through activation of MT1-MMP signaling.
Kang H, Hong Z, Zhong M, Klomp J, Bayless KJ, Mehta D, Karginov AV, Hu G, Malik AB
American journal of physiology. Cell physiology 2019 Jan 1;316(1):C92-C103
American journal of physiology. Cell physiology 2019 Jan 1;316(1):C92-C103
Different Isoforms of the Neuronal Guidance Molecule Slit2 Directly Cause Chemoattraction or Chemorepulsion of Human Neutrophils.
Pilling D, Chinea LE, Consalvo KM, Gomer RH
Journal of immunology (Baltimore, Md. : 1950) 2019 Jan 1;202(1):239-248
Journal of immunology (Baltimore, Md. : 1950) 2019 Jan 1;202(1):239-248
MiR-26a-5p Inhibits Cell Proliferation and Enhances Doxorubicin Sensitivity in HCC Cells via Targeting AURKA.
Yuan YL, Yu H, Mu SM, Dong YD, Li Y
Technology in cancer research & treatment 2019 Jan 1;18:1533033819851833
Technology in cancer research & treatment 2019 Jan 1;18:1533033819851833
Colon Cancer Cell Secretes EGF to Promote M2 Polarization of TAM Through EGFR/PI3K/AKT/mTOR Pathway.
Lian G, Chen S, Ouyang M, Li F, Chen L, Yang J
Technology in cancer research & treatment 2019 Jan 1;18:1533033819849068
Technology in cancer research & treatment 2019 Jan 1;18:1533033819849068
MMP13 inhibition rescues cognitive decline in Alzheimer transgenic mice via BACE1 regulation.
Zhu BL, Long Y, Luo W, Yan Z, Lai YJ, Zhao LG, Zhou WH, Wang YJ, Shen LL, Liu L, Deng XJ, Wang XF, Sun F, Chen GJ
Brain : a journal of neurology 2019 Jan 1;142(1):176-192
Brain : a journal of neurology 2019 Jan 1;142(1):176-192
Genotoxic stress causes the accumulation of DNA-dependent protein kinase catalytic subunit phosphorylated at serine 2056 at nuclear speckles and alters pre-mRNA alternative splicing.
Liu S, Shao Y, Wang Q, Zhai Y, Li X
FEBS open bio 2019 Feb;9(2):304-314
FEBS open bio 2019 Feb;9(2):304-314
High expression of SLC17A9 correlates with poor prognosis in colorectal cancer.
Yang L, Chen Z, Xiong W, Ren H, Zhai E, Xu K, Yang H, Zhang Z, Ding L, He Y, Song X, Liu J
Human pathology 2019 Feb;84:62-70
Human pathology 2019 Feb;84:62-70
MicroRNA-5195-3p plays a suppressive role in cell proliferation, migration and invasion by targeting MYO6 in human non-small cell lung cancer.
Yang Q
Bioscience, biotechnology, and biochemistry 2019 Feb;83(2):212-220
Bioscience, biotechnology, and biochemistry 2019 Feb;83(2):212-220
Early onset developmental delay and epilepsy in pediatric patients with WDR45 variants.
Chen H, Qian Y, Yu S, Xiao D, Guo X, Wang Q, Hao L, Yan K, Lu Y, Dong X, Zhou W, Wu B, Zhou S, Wang H
European journal of medical genetics 2019 Feb;62(2):149-160
European journal of medical genetics 2019 Feb;62(2):149-160
Tunicamycin enhances the suppressive effects of cisplatin on lung cancer growth through PTX3 glycosylation via AKT/NF-κB signaling pathway.
Ahmmed B, Khan MN, Nisar MA, Kampo S, Zheng Q, Li Y, Yan Q
International journal of oncology 2019 Feb;54(2):431-442
International journal of oncology 2019 Feb;54(2):431-442
Increased levels of serum pigment epithelium-derived factor aggravate proteinuria via induction of podocyte actin rearrangement.
Huang N, Zhang X, Jiang Y, Mei H, Zhang L, Zhang Q, Hu J, Chen B
International urology and nephrology 2019 Feb;51(2):359-367
International urology and nephrology 2019 Feb;51(2):359-367
Rapid depletion of ESCRT protein Vps4 underlies injury-induced autophagic impediment and Wallerian degeneration.
Wang H, Wang X, Zhang K, Wang Q, Cao X, Wang Z, Zhang S, Li A, Liu K, Fang Y
Science advances 2019 Feb;5(2):eaav4971
Science advances 2019 Feb;5(2):eaav4971
CXCR4 enhances cisplatin resistance of human tongue squamous cell carcinoma.
Zhuang XM, Zhou B
Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology 2019 Feb;48(2):122-128
Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology 2019 Feb;48(2):122-128
Chlamydia trachomatis plasmid-encoded protein Pgp3 inhibits apoptosis via the PI3K-AKT-mediated MDM2-p53 axis.
Zou Y, Lei W, Su S, Bu J, Zhu S, Huang Q, Li Z
Molecular and cellular biochemistry 2019 Feb;452(1-2):167-176
Molecular and cellular biochemistry 2019 Feb;452(1-2):167-176
The Effects of Mitogen-activated Protein Kinase Signaling Pathways on Lipopolysaccharide-mediated Osteo/Odontogenic Differentiation of Stem Cells from the Apical Papilla.
Liu J, Du J, Chen X, Yang L, Zhao W, Song M, Wang Z, Wang Y
Journal of endodontics 2019 Feb;45(2):161-167
Journal of endodontics 2019 Feb;45(2):161-167
Down-regulation of lncRNA OGFRP1 induces autophagy and growth inhibition by AKT/mTOR signaling pathway in HCAECs.
Zhang X, Liu J, Gu Y, Sun C, Qu F
Cell biology international 2019 Feb;43(2):158-166
Cell biology international 2019 Feb;43(2):158-166
Investigating a chimeric anti-mouse PDGFRα antibody as a radiosensitizer in primary mouse sarcomas.
Song EJ, Ashcraft KA, Lowery CD, Mowery YM, Luo L, Ma Y, Campos LDS, Cardona DM, Stancato L, Kirsch DG
EBioMedicine 2019 Feb;40:224-230
EBioMedicine 2019 Feb;40:224-230
Antiviral activity of bone morphogenetic proteins and activins.
Eddowes LA, Al-Hourani K, Ramamurthy N, Frankish J, Baddock HT, Sandor C, Ryan JD, Fusco DN, Arezes J, Giannoulatou E, Boninsegna S, Chevaliez S, Owens BMJ, Sun CC, Fabris P, Giordani MT, Martines D, Vukicevic S, Crowe J, Lin HY, Rehwinkel J, McHugh PJ, Binder M, Babitt JL, Chung RT, Lawless MW, Armitage AE, Webber C, Klenerman P, Drakesmith H
Nature microbiology 2019 Feb;4(2):339-351
Nature microbiology 2019 Feb;4(2):339-351
Decrease of GSK3β Ser-9 Phosphorylation Induced Osteoblast Apoptosis in Rat Osteoarthritis Model.
Deng S, Nie ZG, Peng PJ, Liu Y, Xing S, Long LS, Peng H
Current medical science 2019 Feb;39(1):75-80
Current medical science 2019 Feb;39(1):75-80
Acetylation of AGO2 promotes cancer progression by increasing oncogenic miR-19b biogenesis.
Zhang H, Wang Y, Dou J, Guo Y, He J, Li L, Liu X, Chen R, Deng R, Huang J, Xie R, Zhao X, Yu J
Oncogene 2019 Feb;38(9):1410-1431
Oncogene 2019 Feb;38(9):1410-1431
Lipopolysaccharide from Escherichia coli stimulates osteogenic differentiation of human periodontal ligament stem cells through Wnt/β-catenin-induced TAZ elevation.
Xing Y, Zhang Y, Jia L, Xu X
Molecular oral microbiology 2019 Feb;34(1)
Molecular oral microbiology 2019 Feb;34(1)
Drastic induction of MMP-7 by cortisol in the human amnion: implications for membrane rupture at parturition.
Wang LY, Wang WS, Wang YW, Lu JW, Lu Y, Zhang CY, Li WJ, Sun K, Ying H
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 Feb;33(2):2770-2781
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 Feb;33(2):2770-2781
Bisphenol A exposure alters placentation and causes preeclampsia-like features in pregnant mice involved in reprogramming of DNA methylation of WNT2.
Ye Y, Tang Y, Xiong Y, Feng L, Li X
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 Feb;33(2):2732-2742
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 Feb;33(2):2732-2742
PPPDE1 promotes hepatocellular carcinoma development by negatively regulate p53 and apoptosis.
Xie X, Wang X, Liao W, Fei R, Wu N, Cong X, Chen Q, Wei L, Wang Y, Chen H
Apoptosis : an international journal on programmed cell death 2019 Feb;24(1-2):135-144
Apoptosis : an international journal on programmed cell death 2019 Feb;24(1-2):135-144
Otx2 enhances transdifferentiation of Müller cells-derived retinal stem cells into photoreceptor-like cells.
Xiong Y, Ji H, You Z, Yao F, Zhou R, Song W, Xia X
Journal of cellular and molecular medicine 2019 Feb;23(2):943-953
Journal of cellular and molecular medicine 2019 Feb;23(2):943-953
Phorbol esters induce PLVAP expression via VEGF and additional secreted molecules in MEK1-dependent and p38, JNK and PI3K/Akt-independent manner.
Hamilton BJ, Tse D, Stan RV
Journal of cellular and molecular medicine 2019 Feb;23(2):920-933
Journal of cellular and molecular medicine 2019 Feb;23(2):920-933
Nucleoporin 107 facilitates the nuclear export of Scn5a mRNA to regulate cardiac bioelectricity.
Guan Y, Gao X, Tang Q, Huang L, Gao S, Yu S, Huang J, Li J, Zhou D, Zhang Y, Shi D, Liang D, Liu Y, Li L, Cui Y, Xu L, Chen YH
Journal of cellular and molecular medicine 2019 Feb;23(2):1448-1457
Journal of cellular and molecular medicine 2019 Feb;23(2):1448-1457
Glucose Signaling Is Connected to Chromosome Segregation Through Protein Kinase A Phosphorylation of the Dam1 Kinetochore Subunit in Saccharomycescerevisiae.
Shah SB, Parmiter D, Constantine C, Elizalde P, Naldrett M, Karpova TS, Choy JS
Genetics 2019 Feb;211(2):531-547
Genetics 2019 Feb;211(2):531-547
Endogenous cholesterol ester hydroperoxides modulate cholesterol levels and inhibit cholesterol uptake in hepatocytes and macrophages.
Guo S, Lu J, Zhuo Y, Xiao M, Xue X, Zhong S, Shen X, Yin C, Li L, Chen Q, Zhu M, Chen B, Zhao M, Zheng L, Tao Y, Yin H
Redox biology 2019 Feb;21:101069
Redox biology 2019 Feb;21:101069
Proteomic Profiling of LPS-Induced Macrophage-Derived Exosomes Indicates Their Involvement in Acute Liver Injury.
Wang G, Jin S, Ling X, Li Y, Hu Y, Zhang Y, Huang Y, Chen T, Lin J, Ning Z, Meng Y, Li X
Proteomics 2019 Feb;19(3):e1800274
Proteomics 2019 Feb;19(3):e1800274
miR-140-5p inhibits cell proliferation and invasion in colorectal carcinoma by targeting SOX4.
Zhao Z, Liu W, Li J
Oncology letters 2019 Feb;17(2):2215-2220
Oncology letters 2019 Feb;17(2):2215-2220
miR-7-5p inhibits cell migration and invasion in glioblastoma through targeting SATB1.
Yin CY, Kong W, Jiang J, Xu H, Zhao W
Oncology letters 2019 Feb;17(2):1819-1825
Oncology letters 2019 Feb;17(2):1819-1825
Ebselen protects rat hearts against myocardial ischemia-reperfusion injury.
Cheng B, Zhong JP, Wu FX, Li GL, Ruan QX, Luo G, Jiang H
Experimental and therapeutic medicine 2019 Feb;17(2):1412-1419
Experimental and therapeutic medicine 2019 Feb;17(2):1412-1419
Motor Neuron Abnormalities Correlate with Impaired Movement in Zebrafish that Express Mutant Superoxide Dismutase 1.
Robinson KJ, Yuan KC, Don EK, Hogan AL, Winnick CG, Tym MC, Lucas CW, Shahheydari H, Watchon M, Blair IP, Atkin JD, Nicholson GA, Cole NJ, Laird AS
Zebrafish 2019 Feb;16(1):8-14
Zebrafish 2019 Feb;16(1):8-14
Doxorubicin conjugated with nanodiamonds and in free form commit glioblastoma cells to heterodromous fates.
Chen Z, Wang C, Li TF, Li K, Yue Y, Liu X, Xu HZ, Wen Y, Zhang Q, Han M, Komatsu N, Xu YH, Zhao L, Chen X
Nanomedicine (London, England) 2019 Feb;14(3):335-351
Nanomedicine (London, England) 2019 Feb;14(3):335-351
Interaction of estrogen receptor β5 and interleukin 6 receptor in the progression of non-small cell lung cancer.
Tang H, Bai Y, Xiong L, Zhang L, Wei Y, Zhu M, Wu X, Long D, Yang J, Yu L, Xu S, Zhao J
Journal of cellular biochemistry 2019 Feb;120(2):2028-2038
Journal of cellular biochemistry 2019 Feb;120(2):2028-2038
Coupling function of cyclin-dependent kinase 2 and Septin2 in the promotion of hepatocellular carcinoma.
Xu C, Zhang W, Zhang X, Zhou D, Qu L, Liu J, Xiao M, Ni R, Jiang F, Ni W, Lu C
Cancer science 2019 Feb;110(2):540-549
Cancer science 2019 Feb;110(2):540-549
MiR-23a-3p acts as an oncogene and potential prognostic biomarker by targeting PNRC2 in RCC.
Quan J, Pan X, Li Y, Hu Y, Tao L, Li Z, Zhao L, Wang J, Li H, Lai Y, Zhou L, Lin C, Gui Y, Ye J, Zhang F, Lai Y
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Feb;110:656-666
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Feb;110:656-666
Long non-coding RNA SNHG6 enhances cell proliferation, migration and invasion by regulating miR-26a-5p/MAPK6 in breast cancer.
Lv P, Qiu X, Gu Y, Yang X, Xu X, Yang Y
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Feb;110:294-301
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Feb;110:294-301
Noradrenergic depletion causes sex specific alterations in the endocannabinoid system in the Murine prefrontal cortex.
Urquhart MA, Ross JA, Reyes BAS, Nitikman M, Thomas SA, Mackie K, Van Bockstaele EJ
Neurobiology of stress 2019 Feb;10:100164
Neurobiology of stress 2019 Feb;10:100164
Combined Single-Cell Profiling of lncRNAs and Functional Screening Reveals that H19 Is Pivotal for Embryonic Hematopoietic Stem Cell Development.
Zhou J, Xu J, Zhang L, Liu S, Ma Y, Wen X, Hao J, Li Z, Ni Y, Li X, Zhou F, Li Q, Wang F, Wang X, Si Y, Zhang P, Liu C, Bartolomei M, Tang F, Liu B, Yu J, Lan Y
Cell stem cell 2019 Feb 7;24(2):285-298.e5
Cell stem cell 2019 Feb 7;24(2):285-298.e5
SNHG1 promotes malignant biological behaviors of glioma cells via microRNA-154-5p/miR-376b-3p- FOXP2- KDM5B participating positive feedback loop.
Li H, Xue Y, Ma J, Shao L, Wang D, Zheng J, Liu X, Yang C, He Q, Ruan X, Li Z, Liu Y
Journal of experimental & clinical cancer research : CR 2019 Feb 6;38(1):59
Journal of experimental & clinical cancer research : CR 2019 Feb 6;38(1):59
Increased expression of thymic stromal lymphopoietin receptor in a rat model of middle cerebral artery occlusion.
Yu X, Zeng K, Liu X, Peng Y, Li C, Fu K, Liang H
Neuroreport 2019 Feb 6;30(3):182-187
Neuroreport 2019 Feb 6;30(3):182-187
Heterozygous Tbk1 loss has opposing effects in early and late stages of ALS in mice.
Brenner D, Sieverding K, Bruno C, Lüningschrör P, Buck E, Mungwa S, Fischer L, Brockmann SJ, Ulmer J, Bliederhäuser C, Philibert CE, Satoh T, Akira S, Boillée S, Mayer B, Sendtner M, Ludolph AC, Danzer KM, Lobsiger CS, Freischmidt A, Weishaupt JH
The Journal of experimental medicine 2019 Feb 4;216(2):267-278
The Journal of experimental medicine 2019 Feb 4;216(2):267-278
LPCAT1 promotes brain metastasis of lung adenocarcinoma by up-regulating PI3K/AKT/MYC pathway.
Wei C, Dong X, Lu H, Tong F, Chen L, Zhang R, Dong J, Hu Y, Wu G, Dong X
Journal of experimental & clinical cancer research : CR 2019 Feb 21;38(1):95
Journal of experimental & clinical cancer research : CR 2019 Feb 21;38(1):95
Lanthanum chloride induces autophagy in rat hippocampus through ROS-mediated JNK and AKT/mTOR signaling pathways.
Gao X, Yang J, Li Y, Yu M, Liu S, Han Y, Lu X, Jin C, Wu S, Cai Y
Metallomics : integrated biometal science 2019 Feb 20;11(2):439-453
Metallomics : integrated biometal science 2019 Feb 20;11(2):439-453
High-fat and high-glucose microenvironment decreases Runx2 and TAZ expression and inhibits bone regeneration in the mouse.
Wu X, Zhang Y, Xing Y, Zhao B, Zhou C, Wen Y, Xu X
Journal of orthopaedic surgery and research 2019 Feb 18;14(1):55
Journal of orthopaedic surgery and research 2019 Feb 18;14(1):55
Novel metabolic disorders in skeletal muscle of Lipodystrophic Bscl2/Seipin deficient mice.
Xu W, Zhou H, Xuan H, Saha P, Wang G, Chen W
Molecular and cellular endocrinology 2019 Feb 15;482:1-10
Molecular and cellular endocrinology 2019 Feb 15;482:1-10
Curcumae Radix Extract Decreases Mammary Tumor-Derived Lung Metastasis via Suppression of C-C Chemokine Receptor Type 7 Expression.
Kaya P, Lee SR, Lee YH, Kwon SW, Yang H, Lee HW, Hong EJ
Nutrients 2019 Feb 15;11(2)
Nutrients 2019 Feb 15;11(2)
Involvement of serum amyloid A1 in the rupture of fetal membranes through induction of collagen I degradation.
Wang WS, Li WJ, Wang YW, Wang LY, Mi YB, Lu JW, Lu Y, Zhang CY, Sun K
Clinical science (London, England : 1979) 2019 Feb 14;133(3):515-530
Clinical science (London, England : 1979) 2019 Feb 14;133(3):515-530
Long non-coding RNA FAM84B-AS promotes resistance of gastric cancer to platinum drugs through inhibition of FAM84B expression.
Zhang Y, Li Q, Yu S, Zhu C, Zhang Z, Cao H, Xu J
Biochemical and biophysical research communications 2019 Feb 12;509(3):753-762
Biochemical and biophysical research communications 2019 Feb 12;509(3):753-762
Ankyrin-G regulated epithelial phenotype is required for mouse lens morphogenesis and growth.
Rasiah PK, Maddala R, Bennett V, Rao PV
Developmental biology 2019 Feb 1;446(1):119-131
Developmental biology 2019 Feb 1;446(1):119-131
Fragment-based drug discovery of triazole inhibitors to block PDEδ-RAS protein-protein interaction.
Chen D, Chen Y, Lian F, Chen L, Li Y, Cao D, Wang X, Chen L, Li J, Meng T, Huang M, Geng M, Shen J, Zhang N, Xiong B
European journal of medicinal chemistry 2019 Feb 1;163:597-609
European journal of medicinal chemistry 2019 Feb 1;163:597-609
Host HDAC4 regulates the antiviral response by inhibiting the phosphorylation of IRF3.
Yang Q, Tang J, Pei R, Gao X, Guo J, Xu C, Wang Y, Wang Q, Wu C, Zhou Y, Hu X, Zhao H, Wang Y, Chen X, Chen J
Journal of molecular cell biology 2019 Feb 1;11(2):158-169
Journal of molecular cell biology 2019 Feb 1;11(2):158-169
MiR-26b suppresses hepatocellular carcinoma development by negatively regulating ZNRD1 and Wnt/β-catenin signaling.
Hu X, Wang R, Ren Z, Liu X, Gu J, Cui G, Li Q
Cancer medicine 2019 Dec;8(17):7359-7371
Cancer medicine 2019 Dec;8(17):7359-7371
Upregulation of CYP2E1 expression causes oxidative damage induced by 2-chloroethanol in primary cultured rat astrocytes.
Tang H, Sun Q, Wang T, Liao Y, Wang G, Zhao F, Jin Y
Neurotoxicology 2019 Dec;75:233-244
Neurotoxicology 2019 Dec;75:233-244
Bioactive molecule Icariin inhibited proliferation while enhanced apoptosis and autophagy of rat airway smooth muscle cells in vitro.
Yang L, Xiao B, Hou L, Zhou G, Mo B, Yao D
Cytotechnology 2019 Dec;71(6):1109-1120
Cytotechnology 2019 Dec;71(6):1109-1120
Upregulated Expression of CUX1 Correlates with Poor Prognosis in Glioma Patients: a Bioinformatic Analysis.
Wu X, Feng F, Yang C, Zhang M, Cheng Y, Zhao Y, Wang Y, Che F, Zhang J, Heng X
Journal of molecular neuroscience : MN 2019 Dec;69(4):527-537
Journal of molecular neuroscience : MN 2019 Dec;69(4):527-537
Molecular mechanism of Bisphenol A on androgen receptor antagonism.
Huang X, Cang X, Liu J
Toxicology in vitro : an international journal published in association with BIBRA 2019 Dec;61:104621
Toxicology in vitro : an international journal published in association with BIBRA 2019 Dec;61:104621
miR-124 ameliorates depressive-like behavior by targeting STAT3 to regulate microglial activation.
Lou D, Wang J, Wang X
Molecular and cellular probes 2019 Dec;48:101470
Molecular and cellular probes 2019 Dec;48:101470
Ribociclib (LEE011) suppresses cell proliferation and induces apoptosis of MDA-MB-231 by inhibiting CDK4/6-cyclin D-Rb-E2F pathway.
Li T, Xiong Y, Wang Q, Chen F, Zeng Y, Yu X, Wang Y, Zhou F, Zhou Y
Artificial cells, nanomedicine, and biotechnology 2019 Dec;47(1):4001-4011
Artificial cells, nanomedicine, and biotechnology 2019 Dec;47(1):4001-4011
Cancer cell membrane cloaking nanoparticles for targeted co-delivery of doxorubicin and PD-L1 siRNA.
Chen M, Chen M, He J
Artificial cells, nanomedicine, and biotechnology 2019 Dec;47(1):1635-1641
Artificial cells, nanomedicine, and biotechnology 2019 Dec;47(1):1635-1641
Palmitoylome profiling indicates that androgens regulate the palmitoylation of α‑tubulin in prostate cancer‑derived LNCaP cells and supernatants.
Li W, Zhang J, Zou L, Cui J, Su F, Jin J, Xiao F, Liu M, Zhao G
Oncology reports 2019 Dec;42(6):2788-2796
Oncology reports 2019 Dec;42(6):2788-2796
Intrathecal injection of dexmedetomidine ameliorates chronic neuropathic pain via the modulation of MPK3/ERK1/2 in a mouse model of chronic neuropathic pain.
Qian Y, Wang Q, Jiao J, Wang G, Gu Z, Huang D, Wang Z
Neurological research 2019 Dec;41(12):1059-1068
Neurological research 2019 Dec;41(12):1059-1068
Mebendazole elicits potent antimyeloma activity by inhibiting the USP5/c-Maf axis.
Chen XH, Xu YJ, Wang XG, Lin P, Cao BY, Zeng YY, Wang Q, Zhang ZB, Mao XL, Zhang T
Acta pharmacologica Sinica 2019 Dec;40(12):1568-1577
Acta pharmacologica Sinica 2019 Dec;40(12):1568-1577
Epigenetic regulation of TIMP1 expression by 8-oxoguanine DNA glycosylase-1 binding to DNA:RNA hybrid.
Pan L, Wang H, Luo J, Zeng J, Pi J, Liu H, Liu C, Ba X, Qu X, Xiang Y, Boldogh I, Qin X
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 Dec;33(12):14159-14170
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 Dec;33(12):14159-14170
Silencing ubiquitin-conjugating enzyme 2C inhibits proliferation and epithelial-mesenchymal transition in pancreatic ductal adenocarcinoma.
Wang X, Yin L, Yang L, Zheng Y, Liu S, Yang J, Cui H, Wang H
The FEBS journal 2019 Dec;286(24):4889-4909
The FEBS journal 2019 Dec;286(24):4889-4909
Rotenone protects against β-cell apoptosis and attenuates type 1 diabetes mellitus.
Wu M, Chen W, Zhang S, Huang S, Zhang A, Zhang Y, Jia Z
Apoptosis : an international journal on programmed cell death 2019 Dec;24(11-12):879-891
Apoptosis : an international journal on programmed cell death 2019 Dec;24(11-12):879-891
STRIP2 silencing inhibits vascular smooth muscle cell proliferation and migration via P38-AKT-MMP-2 signaling pathway.
Dai L, Zhou J, Li T, Qian Y, Jin L, Zhu C, Li S
Journal of cellular physiology 2019 Dec;234(12):22463-22476
Journal of cellular physiology 2019 Dec;234(12):22463-22476
HOXC13-AS promotes breast cancer cell growth through regulating miR-497-5p/PTEN axis.
Li X, Wang Q, Rui Y, Zhang C, Wang W, Gu J, Tang J, Ding Y
Journal of cellular physiology 2019 Dec;234(12):22343-22351
Journal of cellular physiology 2019 Dec;234(12):22343-22351
Integrated analysis of transcriptome data revealed MMP3 and MMP13 as critical genes in anaplastic thyroid cancer progression.
Ma Y, Cang S, Li G, Su Y, Zhang H, Wang L, Yang J, Shi X, Qin G, Yuan H
Journal of cellular physiology 2019 Dec;234(12):22260-22271
Journal of cellular physiology 2019 Dec;234(12):22260-22271
Critical roles of PI3K/Akt/NF‑κB survival axis in angiotensin II‑induced podocyte injury.
Wang J, Fu D, Senouthai S, You Y
Molecular medicine reports 2019 Dec;20(6):5134-5144
Molecular medicine reports 2019 Dec;20(6):5134-5144
PTEN-knockdown disrupts the morphology, growth pattern and function of Nthy-Ori 3-1 cells by downregulating PAX8 expression.
Sun Z, Lu J, Wu M, Ouyang C, Xing Y, Hou X, Shi Z, Wu Y
Oncology letters 2019 Dec;18(6):6732-6740
Oncology letters 2019 Dec;18(6):6732-6740
Receptor tyrosine kinase expression in high-grade gliomas before and after chemoradiotherapy.
Wang K, Huang R, Wu C, Li G, Zhao Z, Hu H, Liu Y
Oncology letters 2019 Dec;18(6):6509-6515
Oncology letters 2019 Dec;18(6):6509-6515
Caffeic acid reduces A53T α-synuclein by activating JNK/Bcl-2-mediated autophagy in vitro and improves behaviour and protects dopaminergic neurons in a mouse model of Parkinson's disease.
Zhang Y, Wu Q, Zhang L, Wang Q, Yang Z, Liu J, Feng L
Pharmacological research 2019 Dec;150:104538
Pharmacological research 2019 Dec;150:104538
Identification of viral SIM-SUMO2-interaction inhibitors for treating primary effusion lymphoma.
Ding L, Zhu Q, Zhou F, Tan H, Xu W, Pan C, Zhu C, Wang Y, Zhang H, Fu W, Qian Z, Yuan Z, Xu H, Wei F, Cai Q
PLoS pathogens 2019 Dec;15(12):e1008174
PLoS pathogens 2019 Dec;15(12):e1008174
Genetic ablation and pharmacological inhibition of immunosubunit β5i attenuates cardiac remodeling in deoxycorticosterone-acetate (DOCA)-salt hypertensive mice.
Cao HJ, Fang J, Zhang YL, Zou LX, Han X, Yang J, Yan X, Li PB, Wang HX, Guo SB, Li HH
Journal of molecular and cellular cardiology 2019 Dec;137:34-45
Journal of molecular and cellular cardiology 2019 Dec;137:34-45
16 T high static magnetic field inhibits receptor activator of nuclear factor kappa-Β ligand-induced osteoclast differentiation by regulating iron metabolism in Raw264.7 cells.
Dong D, Yang J, Zhang G, Huyan T, Shang P
Journal of tissue engineering and regenerative medicine 2019 Dec;13(12):2181-2190
Journal of tissue engineering and regenerative medicine 2019 Dec;13(12):2181-2190
Snail2 induced E-cadherin suppression and metastasis in lung carcinoma facilitated by G9a and HDACs.
Hu Y, Zheng Y, Dai M, Wu J, Yu B, Zhang H, Kong W, Wu H, Yu X
Cell adhesion & migration 2019 Dec;13(1):285-292
Cell adhesion & migration 2019 Dec;13(1):285-292
Platelet endothelial aggregation receptor-1 regulates bovine muscle satellite cell migration and differentiation via integrin beta-1 and focal adhesion kinase.
Pang Y, Zhang Z, Wang Z, Wang Y, Yan Y, Li S, Tong H
Cell adhesion & migration 2019 Dec;13(1):192-202
Cell adhesion & migration 2019 Dec;13(1):192-202
Down-regulated long non-coding RNA PVT1 contributes to gestational diabetes mellitus and preeclampsia via regulation of human trophoblast cells.
Wang Q, Lu X, Li C, Zhang W, Lv Y, Wang L, Wu L, Meng L, Fan Y, Ding H, Long W, Lv M
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Dec;120:109501
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Dec;120:109501
Epigallocatechin-3-gallate inhibits tumor angiogenesis: involvement of endoglin/Smad1 signaling in human umbilical vein endothelium cells.
Chen CY, Lin YJ, Wang CCN, Lan YH, Lan SJ, Sheu MJ
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Dec;120:109491
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Dec;120:109491
Ferulic acid increases intestinal Lactobacillus and improves cardiac function in TAC mice.
Liu Z, Ma Z, Zhang H, Summah BS, Liu H, An D, Zhan Q, Lai W, Zeng Q, Ren H, Xu D
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Dec;120:109482
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Dec;120:109482
Endocytic degradation of ErbB2 mediates the effectiveness of neratinib in the suppression of ErbB2-positive ovarian cancer.
Wang S, Zhang J, Wang T, Ren F, Liu X, Lu Y, Xu L, Zhang Y, Wang D, Xu L, Wu Y, Liu F, Li Q, Zaky MY, Liu S, Dong W, Liu F, Zou K, Zhang Y
The international journal of biochemistry & cell biology 2019 Dec;117:105640
The international journal of biochemistry & cell biology 2019 Dec;117:105640
Forkhead box C1 promotes metastasis and invasion of non-small cell lung cancer by binding directly to the lysyl oxidase promoter.
Gong R, Lin W, Gao A, Liu Y, Li J, Sun M, Chen X, Han S, Men C, Sun Y, Liu J
Cancer science 2019 Dec;110(12):3663-3676
Cancer science 2019 Dec;110(12):3663-3676
Dietary Antioxidant Trans-Cinnamaldehyde Reduced Visfatin-Induced Breast Cancer Progression: In Vivo and In Vitro Study.
Chiang YF, Chen HY, Huang KC, Lin PH, Hsia SM
Antioxidants (Basel, Switzerland) 2019 Dec 6;8(12)
Antioxidants (Basel, Switzerland) 2019 Dec 6;8(12)
Rice Protein Exerts Anti-Inflammatory Effect in Growing and Adult Rats via Suppressing NF-κB Pathway.
Wang Z, Liang M, Li H, Cai L, Yang L
International journal of molecular sciences 2019 Dec 6;20(24)
International journal of molecular sciences 2019 Dec 6;20(24)
Role of linc00174/miR-138-5p (miR-150-5p)/FOSL2 Feedback Loop on Regulating the Blood-Tumor Barrier Permeability.
Guo J, Shen S, Liu X, Ruan X, Zheng J, Liu Y, Liu L, Ma J, Ma T, Shao L, Wang D, Yang C, Xue Y
Molecular therapy. Nucleic acids 2019 Dec 6;18:1072-1090
Molecular therapy. Nucleic acids 2019 Dec 6;18:1072-1090
Grape Seed Proanthocyanidins Induce Autophagy and Modulate Survivin in HepG2 Cells and Inhibit Xenograft Tumor Growth in Vivo.
Wang L, Huang W, Zhan J
Nutrients 2019 Dec 6;11(12)
Nutrients 2019 Dec 6;11(12)
NOS1 inhibits the interferon response of cancer cells by S-nitrosylation of HDAC2.
Xu P, Ye S, Li K, Huang M, Wang Q, Zeng S, Chen X, Gao W, Chen J, Zhang Q, Zhong Z, Lin Y, Rong Z, Xu Y, Hao B, Peng A, Ouyang M, Liu Q
Journal of experimental & clinical cancer research : CR 2019 Dec 5;38(1):483
Journal of experimental & clinical cancer research : CR 2019 Dec 5;38(1):483
Astragaloside IV protects against diabetic nephropathy via activating eNOS in streptozotocin diabetes-induced rats.
Fan Y, Fan H, Zhu B, Zhou Y, Liu Q, Li P
BMC complementary and alternative medicine 2019 Dec 5;19(1):355
BMC complementary and alternative medicine 2019 Dec 5;19(1):355
Celastrol Inhibits Dopaminergic Neuronal Death of Parkinson's Disease through Activating Mitophagy.
Lin MW, Lin CC, Chen YH, Yang HB, Hung SY
Antioxidants (Basel, Switzerland) 2019 Dec 31;9(1)
Antioxidants (Basel, Switzerland) 2019 Dec 31;9(1)
Liver Soluble Epoxide Hydrolase Regulates Behavioral and Cellular Effects of Chronic Stress.
Qin XH, Wu Z, Dong JH, Zeng YN, Xiong WC, Liu C, Wang MY, Zhu MZ, Chen WJ, Zhang Y, Huang QY, Zhu XH
Cell reports 2019 Dec 3;29(10):3223-3234.e6
Cell reports 2019 Dec 3;29(10):3223-3234.e6
BMP10 preserves cardiac function through its dual activation of SMAD-mediated and STAT3-mediated pathways.
Qu X, Liu Y, Cao D, Chen J, Liu Z, Ji H, Chen Y, Zhang W, Zhu P, Xiao D, Li X, Shou W, Chen H
The Journal of biological chemistry 2019 Dec 27;294(52):19877-19888
The Journal of biological chemistry 2019 Dec 27;294(52):19877-19888
The regulatory effect of microRNA-21a-3p on the promotion of telocyte angiogenesis mediated by PI3K (p110α)/AKT/mTOR in LPS induced mice ARDS.
Zhou Y, Yang Y, Liang T, Hu Y, Tang H, Song D, Fang H
Journal of translational medicine 2019 Dec 26;17(1):427
Journal of translational medicine 2019 Dec 26;17(1):427
Antiviral activity of interleukin-11 as a response to porcine epidemic diarrhea virus infection.
Li Y, Wu Q, Jin Y, Yang Q
Veterinary research 2019 Dec 21;50(1):111
Veterinary research 2019 Dec 21;50(1):111
Integrated Metabolomics and Network Pharmacology Strategy-Driven Active Traditional Chinese Medicine Ingredients Discovery for the Alleviation of Cisplatin Nephrotoxicity.
Xu L, Zhang Y, Zhang P, Dai X, Gao Y, Lv Y, Qin S, Xu F
Chemical research in toxicology 2019 Dec 16;32(12):2411-2421
Chemical research in toxicology 2019 Dec 16;32(12):2411-2421
Hypothalamic paraventricular nucleus neurons activated by estrogen GPER1 receptors promote anti-inflammation effects in the early stage of colitis.
Jiang T, Wang R, Yin W, Zhou Y, Kong D, Xu S, Gao P, Yu W, Jiao Y, Wen D
Acta biochimica et biophysica Sinica 2019 Dec 13;51(12):1216-1222
Acta biochimica et biophysica Sinica 2019 Dec 13;51(12):1216-1222
The Human Cytomegalovirus Nonstructural Glycoprotein UL148 Reorganizes the Endoplasmic Reticulum.
Zhang H, Read C, Nguyen CC, Siddiquey MNA, Shang C, Hall CM, von Einem J, Kamil JP
mBio 2019 Dec 10;10(6)
mBio 2019 Dec 10;10(6)
The Combination of Adipose-derived Schwann-like Cells and Acellular Nerve Allografts Promotes Sciatic Nerve Regeneration and Repair through the JAK2/STAT3 Signaling Pathway in Rats.
Fu XM, Wang Y, Fu WL, Liu DH, Zhang CY, Wang QL, Tong XJ
Neuroscience 2019 Dec 1;422:134-145
Neuroscience 2019 Dec 1;422:134-145
Silencing TTK expression inhibits the proliferation and progression of prostate cancer.
Chen S, Wang J, Wang L, Peng H, Xiao L, Li C, Lin D, Yang K
Experimental cell research 2019 Dec 1;385(1):111669
Experimental cell research 2019 Dec 1;385(1):111669
The exocyst complex regulates insulin-stimulated glucose uptake of skeletal muscle cells.
Fujimoto BA, Young M, Carter L, Pang APS, Corley MJ, Fogelgren B, Polgar N
American journal of physiology. Endocrinology and metabolism 2019 Dec 1;317(6):E957-E972
American journal of physiology. Endocrinology and metabolism 2019 Dec 1;317(6):E957-E972
The focal adhesion scaffold protein Hic-5 regulates vimentin organization in fibroblasts.
Vohnoutka RB, Gulvady AC, Goreczny G, Alpha K, Handelman SK, Sexton JZ, Turner CE
Molecular biology of the cell 2019 Dec 1;30(25):3037-3056
Molecular biology of the cell 2019 Dec 1;30(25):3037-3056
Histone deacetylase 6 inhibitor ACY1215 offers a protective effect through the autophagy pathway in acute liver failure.
Chen Q, Wang Y, Jiao FZ, Shi CX, Gong ZJ
Life sciences 2019 Dec 1;238:116976
Life sciences 2019 Dec 1;238:116976
Paper/polymer composited microfluidic platform for screening cell viability and protein expression under a chemical gradient environment.
Lei KF, Goh A, Huang CH
Talanta 2019 Dec 1;205:120124
Talanta 2019 Dec 1;205:120124
Uhrf1-Mediated Tnf-α Gene Methylation Controls Proinflammatory Macrophages in Experimental Colitis Resembling Inflammatory Bowel Disease.
Qi S, Li Y, Dai Z, Xiang M, Wang G, Wang L, Wang Z
Journal of immunology (Baltimore, Md. : 1950) 2019 Dec 1;203(11):3045-3053
Journal of immunology (Baltimore, Md. : 1950) 2019 Dec 1;203(11):3045-3053
Downregulation of TMPRSS4 Enhances Triple-Negative Breast Cancer Cell Radiosensitivity Through Cell Cycle and Cell Apoptosis Process Impairment.
Assani G, Segbo J, Yu X, Yessoufou A, Xiong Y, Zhou F, Zhou Y
Asian Pacific journal of cancer prevention : APJCP 2019 Dec 1;20(12):3679-3687
Asian Pacific journal of cancer prevention : APJCP 2019 Dec 1;20(12):3679-3687
Reduced m6A modification predicts malignant phenotypes and augmented Wnt/PI3K-Akt signaling in gastric cancer.
Zhang C, Zhang M, Ge S, Huang W, Lin X, Gao J, Gong J, Shen L
Cancer medicine 2019 Aug;8(10):4766-4781
Cancer medicine 2019 Aug;8(10):4766-4781
RECQL5 plays an essential role in maintaining genome stability and viability of triple-negative breast cancer cells.
Peng J, Tang L, Cai M, Chen H, Wong J, Zhang P
Cancer medicine 2019 Aug;8(10):4743-4752
Cancer medicine 2019 Aug;8(10):4743-4752
Dexmedetomidine alleviates LPS-induced apoptosis and inflammation in macrophages by eliminating damaged mitochondria via PINK1 mediated mitophagy.
Wang Y, Mao X, Chen H, Feng J, Yan M, Wang Y, Yu Y
International immunopharmacology 2019 Aug;73:471-481
International immunopharmacology 2019 Aug;73:471-481
Sulforaphane inhibits gastric cancer stem cells via suppressing sonic hedgehog pathway.
Ge M, Zhang L, Cao L, Xie C, Li X, Li Y, Meng Y, Chen Y, Wang X, Chen J, Zhang Q, Shao J, Zhong C
International journal of food sciences and nutrition 2019 Aug;70(5):570-578
International journal of food sciences and nutrition 2019 Aug;70(5):570-578
Angiogenic Factor AGGF1-Primed Endothelial Progenitor Cells Repair Vascular Defect in Diabetic Mice.
Yao Y, Li Y, Song Q, Hu C, Xie W, Xu C, Chen Q, Wang QK
Diabetes 2019 Aug;68(8):1635-1648
Diabetes 2019 Aug;68(8):1635-1648
Steroid-Enriched Fraction of Achyranthes bidentata Protects Amyloid β Peptide 1-40-Induced Cognitive Dysfunction and Neuroinflammation in Rats.
Lin LW, Tsai FH, Lan WC, Cheng YD, Lee SC, Wu CR
Molecular neurobiology 2019 Aug;56(8):5671-5688
Molecular neurobiology 2019 Aug;56(8):5671-5688
Pyrroline-5-Carboxylate Reductase 1 Accelerates the Migration and Invasion of Nonsmall Cell Lung Cancer In Vitro.
Sang S, Zhang C, Shan J
Cancer biotherapy & radiopharmaceuticals 2019 Aug;34(6):380-387
Cancer biotherapy & radiopharmaceuticals 2019 Aug;34(6):380-387
Total flavonoids from sea buckthorn ameliorates lipopolysaccharide/cigarette smoke-induced airway inflammation.
Ren QC, Li XH, Li QY, Yang HL, Wang HL, Zhang H, Zhao L, Jiang-Yong SL, Meng XL, Zhang Y, Shen XF
Phytotherapy research : PTR 2019 Aug;33(8):2102-2117
Phytotherapy research : PTR 2019 Aug;33(8):2102-2117
FAT1, a direct transcriptional target of E2F1, suppresses cell proliferation, migration and invasion in esophageal squamous cell carcinoma.
Wang Y, Wang G, Ma Y, Teng J, Wang Y, Cui Y, Dong Y, Shao S, Zhan Q, Liu X
Chinese journal of cancer research = Chung-kuo yen cheng yen chiu 2019 Aug;31(4):609-619
Chinese journal of cancer research = Chung-kuo yen cheng yen chiu 2019 Aug;31(4):609-619
Discovery of a Pathogenic Variant rs139379666 (p. P2974L) in ATM for Breast Cancer Risk in Chinese Populations.
Guo X, Lin W, Bai M, Li H, Wen W, Zeng C, Chen Z, He J, Chen J, Cai Q, Long J, Jia WH, Shu XO, Zheng W
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2019 Aug;28(8):1308-1315
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2019 Aug;28(8):1308-1315
Role of SNHG7-miR-653-5p-STAT2 feedback loop in regulating neuroblastoma progression.
Chi R, Chen X, Liu M, Zhang H, Li F, Fan X, Wang W, Lu H
Journal of cellular physiology 2019 Aug;234(8):13403-13412
Journal of cellular physiology 2019 Aug;234(8):13403-13412
Exosomes from tendon stem cells promote injury tendon healing through balancing synthesis and degradation of the tendon extracellular matrix.
Wang Y, He G, Guo Y, Tang H, Shi Y, Bian X, Zhu M, Kang X, Zhou M, Lyu J, Yang M, Mu M, Lai F, Lu K, Chen W, Zhou B, Zhang J, Tang K
Journal of cellular and molecular medicine 2019 Aug;23(8):5475-5485
Journal of cellular and molecular medicine 2019 Aug;23(8):5475-5485
MANF regulates splenic macrophage differentiation in mice.
Hou C, Wang D, Li X, He Y, Wei C, Jiang R, Liu J, Feng L, Shen Y
Immunology letters 2019 Aug;212:37-45
Immunology letters 2019 Aug;212:37-45
Migrasome formation is mediated by assembly of micron-scale tetraspanin macrodomains.
Huang Y, Zucker B, Zhang S, Elias S, Zhu Y, Chen H, Ding T, Li Y, Sun Y, Lou J, Kozlov MM, Yu L
Nature cell biology 2019 Aug;21(8):991-1002
Nature cell biology 2019 Aug;21(8):991-1002
Migrasomes provide regional cues for organ morphogenesis during zebrafish gastrulation.
Jiang D, Jiang Z, Lu D, Wang X, Liang H, Zhang J, Meng Y, Li Y, Wu D, Huang Y, Chen Y, Deng H, Wu Q, Xiong J, Meng A, Yu L
Nature cell biology 2019 Aug;21(8):966-977
Nature cell biology 2019 Aug;21(8):966-977
Identification of COMMD1 as a novel lamin A binding partner.
Jiang Z, Chen W, Zhou J, Peng Q, Zheng H, Yuan Y, Cui H, Zhao W, Sun X, Zhou Z, Liu X
Molecular medicine reports 2019 Aug;20(2):1790-1796
Molecular medicine reports 2019 Aug;20(2):1790-1796
E3 ligase Fbw7 participates in oxidative stress‑induced myocardial cell injury via interacting with Mcl‑1.
Li X, Zhang N, Zhang Y, Jia P, Guo Y, Tian Y, You S, Wu S, Sun Y
Molecular medicine reports 2019 Aug;20(2):1561-1568
Molecular medicine reports 2019 Aug;20(2):1561-1568
Roseburia intestinalis supernatant ameliorates colitis induced in mice by regulating the immune response.
Luo W, Shen Z, Deng M, Li X, Tan B, Xiao M, Wu S, Yang Z, Zhu C, Tian L, Wu X, Meng X, Quan Y, Wang X
Molecular medicine reports 2019 Aug;20(2):1007-1016
Molecular medicine reports 2019 Aug;20(2):1007-1016
Progranulin Promotes Bleomycin-Induced Skin Sclerosis by Enhancing Transforming Growth Factor-β/Smad3 Signaling through Up-Regulation of Transforming Growth Factor-β Type I Receptor.
Yang T, Zhang X, Chen A, Xiao Y, Sun S, Yan J, Cao Y, Chen J, Li F, Zhang Q, Huang K
The American journal of pathology 2019 Aug;189(8):1582-1593
The American journal of pathology 2019 Aug;189(8):1582-1593
Fibronectin regulates the self-renewal of rabbit limbal epithelial stem cells by stimulating the Wnt11/Fzd7/ROCK non-canonical Wnt pathway.
Zheng M, Tian C, Fan T, Xu B
Experimental eye research 2019 Aug;185:107681
Experimental eye research 2019 Aug;185:107681
MicroRNA-2053 overexpression inhibits the development and progression of hepatocellular carcinoma.
Song T, Ma K, Zhao C, Yang J, Liu J
Oncology letters 2019 Aug;18(2):2043-2049
Oncology letters 2019 Aug;18(2):2043-2049
Ursolic acid isolated from Isodon excisoides induces apoptosis and inhibits invasion of GBC-SD gallbladder carcinoma cells.
Chen H, Wu X, Duan Y, Zhi D, Zou M, Zhao Z, Zhang X, Yang X, Zhang J
Oncology letters 2019 Aug;18(2):1467-1474
Oncology letters 2019 Aug;18(2):1467-1474
Inducible LGALS3BP/90K activates antiviral innate immune responses by targeting TRAF6 and TRAF3 complex.
Xu G, Xia Z, Deng F, Liu L, Wang Q, Yu Y, Wang F, Zhu C, Liu W, Cheng Z, Zhu Y, Zhou L, Zhang Y, Lu M, Liu S
PLoS pathogens 2019 Aug;15(8):e1008002
PLoS pathogens 2019 Aug;15(8):e1008002
Sesterterpene MHO7 suppresses breast cancer cells as a novel estrogen receptor degrader.
Zhao Y, Zhao C, Lu J, Wu J, Li C, Hu Z, Tian W, Yang L, Xiang J, Zhou H, Deng Z, Huang J, Hong K
Pharmacological research 2019 Aug;146:104294
Pharmacological research 2019 Aug;146:104294
MicroRNA-128-3p aggravates doxorubicin-induced liver injury by promoting oxidative stress via targeting Sirtuin-1.
Zhao X, Jin Y, Li L, Xu L, Tang Z, Qi Y, Yin L, Peng J
Pharmacological research 2019 Aug;146:104276
Pharmacological research 2019 Aug;146:104276
Inhibitor of growth 4 (ING4) inhibits hypoxia-induced EMT by decreasing HIF-1α and snail in HK2 cells.
Lu L, Li J, Le Y, Jiang H
Acta histochemica 2019 Aug;121(6):695-703
Acta histochemica 2019 Aug;121(6):695-703
STAT3-induced long noncoding RNA LINC00668 promotes migration and invasion of non-small cell lung cancer via the miR-193a/KLF7 axis.
An YX, Shang YJ, Xu ZW, Zhang QC, Wang Z, Xuan WX, Zhang XJ
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Aug;116:109023
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Aug;116:109023
Ablation of core fucosylation attenuates the signal transduction via T cell receptor to suppress the T cell development.
Liang W, Mao S, Li M, Zhang N, Sun S, Fang H, Zhang J, Gu J, Wang J, Li W
Molecular immunology 2019 Aug;112:312-321
Molecular immunology 2019 Aug;112:312-321
Vasorin stimulates malignant progression and angiogenesis in glioma.
Liang W, Guo B, Ye J, Liu H, Deng W, Lin C, Zhong X, Wang L
Cancer science 2019 Aug;110(8):2558-2572
Cancer science 2019 Aug;110(8):2558-2572
CircAGFG1 sponges miR-203 to promote EMT and metastasis of non-small-cell lung cancer by upregulating ZNF281 expression.
Xue YB, Ding MQ, Xue L, Luo JH
Thoracic cancer 2019 Aug;10(8):1692-1701
Thoracic cancer 2019 Aug;10(8):1692-1701
Extracellular Vesicles from Albumin-Induced Tubular Epithelial Cells Promote the M1 Macrophage Phenotype by Targeting Klotho.
Jia Y, Zheng Z, Xue M, Zhang S, Hu F, Li Y, Yang Y, Zou M, Li S, Wang L, Guan M, Xue Y
Molecular therapy : the journal of the American Society of Gene Therapy 2019 Aug 7;27(8):1452-1466
Molecular therapy : the journal of the American Society of Gene Therapy 2019 Aug 7;27(8):1452-1466
LncRNA MEG3 acts a biomarker and regulates cell functions by targeting ADAR1 in colorectal cancer.
Wang W, Xie Y, Chen F, Liu X, Zhong LL, Wang HQ, Li QC
World journal of gastroenterology 2019 Aug 7;25(29):3972-3984
World journal of gastroenterology 2019 Aug 7;25(29):3972-3984
Berberine prevents stress-induced gut inflammation and visceral hypersensitivity and reduces intestinal motility in rats.
Yu ZC, Cen YX, Wu BH, Wei C, Xiong F, Li DF, Liu TT, Luo MH, Guo LL, Li YX, Wang LS, Wang JY, Yao J
World journal of gastroenterology 2019 Aug 7;25(29):3956-3971
World journal of gastroenterology 2019 Aug 7;25(29):3956-3971
Isoliquiritigenin Suppresses E2-Induced Uterine Leiomyoma Growth through the Modulation of Cell Death Program and the Repression of ECM Accumulation.
Lin PH, Kung HL, Chen HY, Huang KC, Hsia SM
Cancers 2019 Aug 7;11(8)
Cancers 2019 Aug 7;11(8)
A novel role for NFIA in restoring radiosensitivity in radioresistant NSCLC cells by downregulating the AKT and ERK pathways.
Sun C, Li Y, Tan Y, Zhang H, Liang Y, Zeng J, Yu J, Zou H
Biochemical and biophysical research communications 2019 Aug 6;515(4):558-564
Biochemical and biophysical research communications 2019 Aug 6;515(4):558-564
Mitochondrial NOS1 suppresses apoptosis in colon cancer cells through increasing SIRT3 activity.
Wang Q, Ye S, Chen X, Xu P, Li K, Zeng S, Huang M, Gao W, Chen J, Zhang Q, Zhong Z, Liu Q
Biochemical and biophysical research communications 2019 Aug 6;515(4):517-523
Biochemical and biophysical research communications 2019 Aug 6;515(4):517-523
TFEB-driven autophagy potentiates TGF-β induced migration in pancreatic cancer cells.
He R, Wang M, Zhao C, Shen M, Yu Y, He L, Zhao Y, Chen H, Shi X, Zhou M, Pan S, Liu Y, Guo X, Li X, Qin R
Journal of experimental & clinical cancer research : CR 2019 Aug 6;38(1):340
Journal of experimental & clinical cancer research : CR 2019 Aug 6;38(1):340
Generation of Human Fatty Livers Using Custom-Engineered Induced Pluripotent Stem Cells with Modifiable SIRT1 Metabolism.
Collin de l'Hortet A, Takeishi K, Guzman-Lepe J, Morita K, Achreja A, Popovic B, Wang Y, Handa K, Mittal A, Meurs N, Zhu Z, Weinberg F, Salomon M, Fox IJ, Deng CX, Nagrath D, Soto-Gutierrez A
Cell metabolism 2019 Aug 6;30(2):385-401.e9
Cell metabolism 2019 Aug 6;30(2):385-401.e9
Simvastatin inhibits the proliferation of HL-60 clone 15- derived eosinophils by inducing the arrest of the cell cycle in the G1/S phase.
Fu CH, Lee TJ, Huang CC, Chang PH, Tsai JW, Chuang LP, Su Pang JH
European journal of pharmacology 2019 Aug 5;856:172400
European journal of pharmacology 2019 Aug 5;856:172400
Endoplasmic reticulum stress and proteasome pathway involvement in human podocyte injury with a truncated COL4A3 mutation.
Zhang HD, Huang JN, Liu YZ, Ren H, Xie JY, Chen N
Chinese medical journal 2019 Aug 5;132(15):1823-1832
Chinese medical journal 2019 Aug 5;132(15):1823-1832
CBX8 promotes tumorigenesis and confers radioresistance in esophageal squamous cell carcinoma cells through targeting APAF1.
Zhang Y, Chen H, Zhu H, Sun X
Gene 2019 Aug 30;711:143949
Gene 2019 Aug 30;711:143949
Ibuprofen inhibited migration of skeletal muscle cells in association with downregulation of p130cas and CrkII expressions.
Liao CH, Lin LP, Yu TY, Hsu CC, Pang JS, Tsai WC
Skeletal muscle 2019 Aug 29;9(1):23
Skeletal muscle 2019 Aug 29;9(1):23
EXT1, Regulated by MiR-665, Promotes Cell Apoptosis via ERK1/2 Signaling Pathway in Acute Lymphoblastic Leukemia.
Liu NW, Huang X, Liu S, Lu Y
Medical science monitor : international medical journal of experimental and clinical research 2019 Aug 29;25:6491-6503
Medical science monitor : international medical journal of experimental and clinical research 2019 Aug 29;25:6491-6503
Identification of Glyceraldehyde-3-Phosphate Dehydrogenase Gene as an Alternative Safe Harbor Locus in Pig Genome.
Han X, Xiong Y, Zhao C, Xie S, Li C, Li X, Liu X, Li K, Zhao S, Ruan J
Genes 2019 Aug 29;10(9)
Genes 2019 Aug 29;10(9)
SIV-Mediated Synaptic Dysfunction Is Associated with an Increase in Synapsin Site 1 Phosphorylation and Impaired PP2A Activity.
Shekarabi M, Robinson JA, Smith MD, Burdo TH
The Journal of neuroscience : the official journal of the Society for Neuroscience 2019 Aug 28;39(35):7006-7018
The Journal of neuroscience : the official journal of the Society for Neuroscience 2019 Aug 28;39(35):7006-7018
Nelfinavir and lenalidomide/dexamethasone in patients with lenalidomide-refractory multiple myeloma. A phase I/II Trial (SAKK 39/10).
Hitz F, Kraus M, Pabst T, Hess D, Besse L, Silzle T, Novak U, Seipel K, Rondeau S, Stüdeli S, Vilei SB, Samaras P, Mey U, Driessen C, Swiss Group for Clinical Cancer Research SAKK
Blood cancer journal 2019 Aug 27;9(9):70
Blood cancer journal 2019 Aug 27;9(9):70
Anti-high mobility group box-1 antibody attenuated vascular smooth muscle cell phenotypic switching and vascular remodelling after subarachnoid haemorrhage in rats.
Wang L, Zhang Z, Liang L, Wu Y, Zhong J, Sun X
Neuroscience letters 2019 Aug 24;708:134338
Neuroscience letters 2019 Aug 24;708:134338
Topoisomerase inhibitors promote cancer cell motility via ROS-mediated activation of JAK2-STAT1-CXCL1 pathway.
Liu J, Qu L, Meng L, Shou C
Journal of experimental & clinical cancer research : CR 2019 Aug 22;38(1):370
Journal of experimental & clinical cancer research : CR 2019 Aug 22;38(1):370
CircRNA CBL.11 suppresses cell proliferation by sponging miR-6778-5p in colorectal cancer.
Li H, Jin X, Liu B, Zhang P, Chen W, Li Q
BMC cancer 2019 Aug 22;19(1):826
BMC cancer 2019 Aug 22;19(1):826
Depletion of phosphatidylinositol 4-phosphate at the Golgi translocates K-Ras to mitochondria.
Miller TE, Henkels KM, Huddleston M, Salisbury R, Hussain SM, Sasaki AT, Cho KJ
Journal of cell science 2019 Aug 22;132(16)
Journal of cell science 2019 Aug 22;132(16)
MiR-1197-3p regulates testosterone secretion in goat Leydig cells via targeting PPARGC1A.
An SY, Zhang GM, Liu ZF, Zhou C, Yang PC, Wang F
Gene 2019 Aug 20;710:131-139
Gene 2019 Aug 20;710:131-139
CBX3/HP1γ promotes tumor proliferation and predicts poor survival in hepatocellular carcinoma.
Zhong X, Kan A, Zhang W, Zhou J, Zhang H, Chen J, Tang S
Aging 2019 Aug 2;11(15):5483-5497
Aging 2019 Aug 2;11(15):5483-5497
Internalization Characterization of Si Nanorod with Camouflaged Cell Membrane Proteins Reveals ATXN2 as a Negative Regulator.
Lu Y, Dai J, Kong N, Liu J, Gong J, Yao Y
Cells 2019 Aug 19;8(8)
Cells 2019 Aug 19;8(8)
Combined Assembly and Targeted Integration of Multigene for Nitrogenase Biosynthetic Pathway in Saccharomyces cerevisiae.
Liu X, Wang M, Song Y, Li Y, Liu P, Shi H, Li Y, Hao T, Zhang H, Jiang W, Chen S, Li J
ACS synthetic biology 2019 Aug 16;8(8):1766-1775
ACS synthetic biology 2019 Aug 16;8(8):1766-1775
CRABP2 regulates invasion and metastasis of breast cancer through hippo pathway dependent on ER status.
Feng X, Zhang M, Wang B, Zhou C, Mu Y, Li J, Liu X, Wang Y, Song Z, Liu P
Journal of experimental & clinical cancer research : CR 2019 Aug 16;38(1):361
Journal of experimental & clinical cancer research : CR 2019 Aug 16;38(1):361
miR-504 suppresses mesenchymal phenotype of glioblastoma by directly targeting the FZD7-mediated Wnt-β-catenin pathway.
Liu Q, Guan Y, Li Z, Wang Y, Liu Y, Cui R, Wang Y
Journal of experimental & clinical cancer research : CR 2019 Aug 16;38(1):358
Journal of experimental & clinical cancer research : CR 2019 Aug 16;38(1):358
IMM-H007 improves heart function via reducing cardiac fibrosis.
Ge W, Zhang W, Gao R, Li B, Zhu H, Wang J
European journal of pharmacology 2019 Aug 15;857:172442
European journal of pharmacology 2019 Aug 15;857:172442
The combination of lonafarnib and sorafenib induces cyclin D1 degradation via ATG3-mediated autophagic flux in hepatocellular carcinoma cells.
Wang J, Wei H, Huang Y, Chen D, Zeng G, Lian Y, Huang Y
Aging 2019 Aug 13;11(15):5769-5785
Aging 2019 Aug 13;11(15):5769-5785
Induction of Fibroblast Senescence During Mouse Corneal Wound Healing.
Wang X, Qu M, Li J, Danielson P, Yang L, Zhou Q
Investigative ophthalmology & visual science 2019 Aug 1;60(10):3669-3679
Investigative ophthalmology & visual science 2019 Aug 1;60(10):3669-3679
Corneal Denervation Causes Epithelial Apoptosis Through Inhibiting NAD+ Biosynthesis.
Li Y, Ma X, Li J, Yang L, Zhao X, Qi X, Zhang X, Zhou Q, Shi W
Investigative ophthalmology & visual science 2019 Aug 1;60(10):3538-3546
Investigative ophthalmology & visual science 2019 Aug 1;60(10):3538-3546
p21-Activated kinase 3 promotes cancer stem cell phenotypes through activating the Akt-GSK3β-β-catenin signaling pathway in pancreatic cancer cells.
Wu HY, Yang MC, Ding LY, Chen CS, Chu PC
Cancer letters 2019 Aug 1;456:13-22
Cancer letters 2019 Aug 1;456:13-22
Retinol binding protein 4 mediates MEHP-induced glucometabolic abnormalities in HepG2 cells.
Wang F, Chang C, Li R, Zhang Z, Jiang H, Zeng N, Li D, Chen L, Xiao Y, Chen W, Wang Q
Toxicology 2019 Aug 1;424:152236
Toxicology 2019 Aug 1;424:152236
RUNX1 promotes tumour metastasis by activating the Wnt/β-catenin signalling pathway and EMT in colorectal cancer.
Li Q, Lai Q, He C, Fang Y, Yan Q, Zhang Y, Wang X, Gu C, Wang Y, Ye L, Han L, Lin X, Chen J, Cai J, Li A, Liu S
Journal of experimental & clinical cancer research : CR 2019 Aug 1;38(1):334
Journal of experimental & clinical cancer research : CR 2019 Aug 1;38(1):334
Amyotrophic lateral sclerosis-associated TDP-43 mutation Q331K prevents nuclear translocation of XRCC4-DNA ligase 4 complex and is linked to genome damage-mediated neuronal apoptosis.
Guerrero EN, Mitra J, Wang H, Rangaswamy S, Hegde PM, Basu P, Rao KS, Hegde ML
Human molecular genetics 2019 Aug 1;28(15):2459-2476
Human molecular genetics 2019 Aug 1;28(15):2459-2476
Roseburia intestinalis inhibits oncostatin M and maintains tight junction integrity in a murine model of acute experimental colitis.
Tan B, Luo W, Shen Z, Xiao M, Wu S, Meng X, Wu X, Yang Z, Tian L, Wang X
Scandinavian journal of gastroenterology 2019 Apr;54(4):432-440
Scandinavian journal of gastroenterology 2019 Apr;54(4):432-440
Adaptive EGF expression sensitizes pancreatic cancer cells to ionizing radiation through activation of the cyclin D1/P53/PARP pathway.
Liu X, Chen H, Hou Y, Ma X, Ye M, Huang R, Hu B, Cao H, Xu L, Liu M, Li L, Gao J, Bai Y
International journal of oncology 2019 Apr;54(4):1466-1480
International journal of oncology 2019 Apr;54(4):1466-1480
Expression patterns of C1ql4 and its cell-adhesion GPCR Bai3 in the murine testis and functional roles in steroidogenesis.
Tan A, Ke S, Chen Y, Chen L, Lu X, Ding F, Yang L, Tang Y, Yu Y
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 Apr;33(4):4893-4906
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 Apr;33(4):4893-4906
Treatment with metformin prevents myocardial ischemia-reperfusion injury via STEAP4 signaling pathway.
Luo T, Zeng X, Yang W, Zhang Y
Anatolian journal of cardiology 2019 Apr;21(5):261-271
Anatolian journal of cardiology 2019 Apr;21(5):261-271
Comparative localization of cystathionine beta synthases and cystathionine gamma lyase in canine, non-human primate and human retina.
Badiei A, Sudharsan R, Santana E, Dunaief JL, Aguirre GD
Experimental eye research 2019 Apr;181:72-84
Experimental eye research 2019 Apr;181:72-84
Type III interferon-induced CBFβ inhibits HBV replication by hijacking HBx.
Xu F, Song H, Xiao Q, Li N, Zhang H, Cheng G, Tan G
Cellular & molecular immunology 2019 Apr;16(4):357-366
Cellular & molecular immunology 2019 Apr;16(4):357-366
5-(3,4-Difluorophenyl)-3-(6-methylpyridin-3-yl)-1,2,4-oxadiazole (DDO-7263), a novel Nrf2 activator targeting brain tissue, protects against MPTP-induced subacute Parkinson's disease in mice by inhibiting the NLRP3 inflammasome and protects PC12 cells against oxidative stress.
Xu LL, Wu YF, Yan F, Li CC, Dai Z, You QD, Jiang ZY, Di B
Free radical biology & medicine 2019 Apr;134:288-303
Free radical biology & medicine 2019 Apr;134:288-303
Role of p53 mediated miR-23a/CXCL12 pathway in osteogenic differentiation of bone mesenchymal stem cells on nanostructured titanium surfaces.
Zhuang XM, Zhou B, Yuan KF
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Apr;112:108649
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Apr;112:108649
Ribociclib, a selective cyclin D kinase 4/6 inhibitor, inhibits proliferation and induces apoptosis of human cervical cancer in vitro and in vivo.
Xiong Y, Li T, Assani G, Ling H, Zhou Q, Zeng Y, Zhou F, Zhou Y
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Apr;112:108602
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Apr;112:108602
Adjudin synergizes with paclitaxel and inhibits cell growth and metastasis by regulating the sirtuin 3-Forkhead box O3a axis in human small-cell lung cancer.
Wang X, Zeng Q, Li Z, Yang X, Xia W, Chen Z
Thoracic cancer 2019 Apr;10(4):642-658
Thoracic cancer 2019 Apr;10(4):642-658
Oxytocin Receptor Antagonists, Atosiban and Nolasiban, Inhibit Prostaglandin F(2α)-induced Contractions and Inflammatory Responses in Human Myometrium.
Kim SH, Riaposova L, Ahmed H, Pohl O, Chollet A, Gotteland JP, Hanyaloglu A, Bennett PR, Terzidou V
Scientific reports 2019 Apr 8;9(1):5792
Scientific reports 2019 Apr 8;9(1):5792
GTSE1 is involved in breast cancer progression in p53 mutation-dependent manner.
Lin F, Xie YJ, Zhang XK, Huang TJ, Xu HF, Mei Y, Liang H, Hu H, Lin ST, Luo FF, Lang YH, Peng LX, Qian CN, Huang BJ
Journal of experimental & clinical cancer research : CR 2019 Apr 8;38(1):152
Journal of experimental & clinical cancer research : CR 2019 Apr 8;38(1):152
HAMP Downregulation Contributes to Aggressive Hepatocellular Carcinoma via Mechanism Mediated by Cyclin4-Dependent Kinase-1/STAT3 Pathway.
Shen Y, Li X, Su Y, Badshah SA, Zhang B, Xue Y, Shang P
Diagnostics (Basel, Switzerland) 2019 Apr 30;9(2)
Diagnostics (Basel, Switzerland) 2019 Apr 30;9(2)
TMEM30A deficiency in endothelial cells impairs cell proliferation and angiogenesis.
Zhang S, Liu W, Yang Y, Sun K, Li S, Xu H, Yang M, Zhang L, Zhu X
Journal of cell science 2019 Apr 3;132(7)
Journal of cell science 2019 Apr 3;132(7)
FOXO1-regulated lncRNA LINC01197 inhibits pancreatic adenocarcinoma cell proliferation by restraining Wnt/β-catenin signaling.
Ling J, Wang F, Liu C, Dong X, Xue Y, Jia X, Song W, Li Q
Journal of experimental & clinical cancer research : CR 2019 Apr 26;38(1):179
Journal of experimental & clinical cancer research : CR 2019 Apr 26;38(1):179
Numb inhibits epithelial-mesenchymal transition via RBP-Jκ-dependent Notch1/PTEN/FAK signaling pathway in tongue cancer.
Li JY, Huang WX, Zhou X, Chen J, Li Z
BMC cancer 2019 Apr 25;19(1):391
BMC cancer 2019 Apr 25;19(1):391
YAP Aggravates Inflammatory Bowel Disease by Regulating M1/M2 Macrophage Polarization and Gut Microbial Homeostasis.
Zhou X, Li W, Wang S, Zhang P, Wang Q, Xiao J, Zhang C, Zheng X, Xu X, Xue S, Hui L, Ji H, Wei B, Wang H
Cell reports 2019 Apr 23;27(4):1176-1189.e5
Cell reports 2019 Apr 23;27(4):1176-1189.e5
Crosstalk Between Connexin32 and Mitochondrial Apoptotic Signaling Pathway Plays a Pivotal Role in Renal Ischemia Reperfusion-Induced Acute Kidney Injury.
Chen C, Yao W, Wu S, Zhou S, Ge M, Gu Y, Li X, Chen G, Bellanti JA, Zheng SG, Yuan D, Hei Z
Antioxidants & redox signaling 2019 Apr 20;30(12):1521-1538
Antioxidants & redox signaling 2019 Apr 20;30(12):1521-1538
Stabilized Peptide HDAC Inhibitors Derived from HDAC1 Substrate H3K56 for the Treatment of Cancer Stem-Like Cells In Vivo.
Wang D, Li W, Zhao R, Chen L, Liu N, Tian Y, Zhao H, Xie M, Lu F, Fang Q, Liang W, Yin F, Li Z
Cancer research 2019 Apr 15;79(8):1769-1783
Cancer research 2019 Apr 15;79(8):1769-1783
Benzoxazine monomer derived carbon dots as a broad-spectrum agent to block viral infectivity.
Huang S, Gu J, Ye J, Fang B, Wan S, Wang C, Ashraf U, Li Q, Wang X, Shao L, Song Y, Zheng X, Cao F, Cao S
Journal of colloid and interface science 2019 Apr 15;542:198-206
Journal of colloid and interface science 2019 Apr 15;542:198-206
Proteomic analysis of mouse ovaries during the prepubertal stages.
Xiong J, Wu M, Zhang Q, Zhang C, Xiong G, Ma L, Lu Z, Wang S
Experimental cell research 2019 Apr 15;377(1-2):36-46
Experimental cell research 2019 Apr 15;377(1-2):36-46
Activation of GPR40 produces mechanical antiallodynia via the spinal glial interleukin-10/β-endorphin pathway.
Mao XF, Wu HY, Tang XQ, Ali U, Liu H, Wang YX
Journal of neuroinflammation 2019 Apr 13;16(1):84
Journal of neuroinflammation 2019 Apr 13;16(1):84
CDK4/6 inhibitor palbociclib enhances the effect of pyrotinib in HER2-positive breast cancer.
Zhang K, Hong R, Kaping L, Xu F, Xia W, Qin G, Zheng Q, Lu Q, Zhai Q, Shi Y, Yuan Z, Deng W, Chen M, Wang S
Cancer letters 2019 Apr 10;447:130-140
Cancer letters 2019 Apr 10;447:130-140
Mild thermotherapy and hyperbaric oxygen enhance sensitivity of TMZ/PSi nanoparticles via decreasing the stemness in glioma.
Zeng X, Wang Q, Tan X, Jia L, Li Y, Hu M, Zhang Z, Bai X, Zhu Y, Yang X
Journal of nanobiotechnology 2019 Apr 1;17(1):47
Journal of nanobiotechnology 2019 Apr 1;17(1):47
The HMGA2-IMP2 Pathway Promotes Granulosa Cell Proliferation in Polycystic Ovary Syndrome.
Li M, Zhao H, Zhao SG, Wei DM, Zhao YR, Huang T, Muhammad T, Yan L, Gao F, Li L, Lu G, Chan WY, Leung PCK, Dunaif A, Liu HB, Chen ZJ
The Journal of clinical endocrinology and metabolism 2019 Apr 1;104(4):1049-1059
The Journal of clinical endocrinology and metabolism 2019 Apr 1;104(4):1049-1059
Exosomal ephrinA2 derived from serum as a potential biomarker for prostate cancer.
Li S, Zhao Y, Chen W, Yin L, Zhu J, Zhang H, Cai C, Li P, Huang L, Ma P
Journal of Cancer 2018;9(15):2659-2665
Journal of Cancer 2018;9(15):2659-2665
P21-activated kinase 7 (PAK7) interacts with and activates Wnt/β-catenin signaling pathway in breast cancer.
Li K, Xu X, He Y, Tian Y, Pan W, Xu L, Ma Y, Gao Y, Gao J, Qi Y, Wei L, Zhang J
Journal of Cancer 2018;9(10):1821-1835
Journal of Cancer 2018;9(10):1821-1835
TANK-Binding Kinase 1 (TBK1) Isoforms Negatively Regulate Type I Interferon Induction by Inhibiting TBK1-IRF3 Interaction and IRF3 Phosphorylation.
Hu YW, Zhang J, Wu XM, Cao L, Nie P, Chang MX
Frontiers in immunology 2018;9:84
Frontiers in immunology 2018;9:84
Core Fucosylation of the T Cell Receptor Is Required for T Cell Activation.
Liang W, Mao S, Sun S, Li M, Li Z, Yu R, Ma T, Gu J, Zhang J, Taniguchi N, Li W
Frontiers in immunology 2018;9:78
Frontiers in immunology 2018;9:78
Fertility Enhancement but Premature Ovarian Failure in esr1-Deficient Female Zebrafish.
Chen Y, Tang H, Wang L, He J, Guo Y, Liu Y, Liu X, Lin H
Frontiers in endocrinology 2018;9:567
Frontiers in endocrinology 2018;9:567
Bioinformatics Analysis Identifies p53 as a Candidate Prognostic Biomarker for Neuropathic Pain.
Gao Y, Sun N, Wang L, Wu Y, Ma L, Hong J, Ren J, Zhu B, Yu L, Yan M
Frontiers in genetics 2018;9:320
Frontiers in genetics 2018;9:320
The Host Restriction Factor Interferon-Inducible Transmembrane Protein 3 Inhibits Vaccinia Virus Infection.
Li C, Du S, Tian M, Wang Y, Bai J, Tan P, Liu W, Yin R, Wang M, Jiang Y, Li Y, Zhu N, Zhu Y, Li T, Wu S, Jin N, He F
Frontiers in immunology 2018;9:228
Frontiers in immunology 2018;9:228
Tc17/IL-17A Up-Regulated the Expression of MMP-9 via NF-κB Pathway in Nasal Epithelial Cells of Patients With Chronic Rhinosinusitis.
Chen X, Chang L, Li X, Huang J, Yang L, Lai X, Huang Z, Wang Z, Wu X, Zhao J, Bellanti JA, Zheng SG, Zhang G
Frontiers in immunology 2018;9:2121
Frontiers in immunology 2018;9:2121
Sesamin Protects the Femoral Head From Osteonecrosis by Inhibiting ROS-Induced Osteoblast Apoptosis in Rat Model.
Deng S, Zhou JL, Fang HS, Nie ZG, Chen S, Peng H
Frontiers in physiology 2018;9:1787
Frontiers in physiology 2018;9:1787
Lactobacillus rhamnosus GR-1 Ameliorates Escherichia coli-Induced Activation of NLRP3 and NLRC4 Inflammasomes With Differential Requirement for ASC.
Wu Q, Zhu YH, Xu J, Liu X, Duan C, Wang MJ, Wang JF
Frontiers in microbiology 2018;9:1661
Frontiers in microbiology 2018;9:1661
Effective Amelioration of Liver Fibrosis Through Lentiviral Vector Carrying Toxoplasma gondii gra15(II) in Murine Model.
Liu L, Jin M, Tao Q, Yu L, Du J, Wang C, Luo Q, Xing T, Xu Y, Shen J, Chu D
Frontiers in immunology 2018;9:1572
Frontiers in immunology 2018;9:1572
MicroRNA-181a Functions as an Oncogene in Gastric Cancer by Targeting Caprin-1.
Lu Q, Chen Y, Sun D, Wang S, Ding K, Liu M, Zhang Y, Miao Y, Liu H, Zhou F
Frontiers in pharmacology 2018;9:1565
Frontiers in pharmacology 2018;9:1565
DEAD-Box Helicase 5 Interacts With Transcription Factor 12 and Promotes the Progression of Osteosarcoma by Stimulating Cell Cycle Progression.
Chen Y, Wang Q, Wang Q, Liu J, Jiang X, Zhang Y, Liu Y, Zhou F, Liu H
Frontiers in pharmacology 2018;9:1558
Frontiers in pharmacology 2018;9:1558
Coagulation Factor X Regulated by CASC2c Recruited Macrophages and Induced M2 Polarization in Glioblastoma Multiforme.
Zhang Y, Feng J, Fu H, Liu C, Yu Z, Sun Y, She X, Li P, Zhao C, Liu Y, Liu T, Liu Q, Liu Q, Li G, Wu M
Frontiers in immunology 2018;9:1557
Frontiers in immunology 2018;9:1557
Latent Membrane Protein 1 of Epstein-Barr Virus Promotes RIG-I Degradation Mediated by Proteasome Pathway.
Xu C, Sun L, Liu W, Duan Z
Frontiers in immunology 2018;9:1446
Frontiers in immunology 2018;9:1446
Invalidation of Microsomal Prostaglandin E Synthase-1 (mPGES-1) Reduces Diet-Induced Low-Grade Inflammation and Adiposity.
Pierre C, Guillebaud F, Airault C, Baril N, Barbouche R, Save E, Gaigé S, Bariohay B, Dallaporta M, Troadec JD
Frontiers in physiology 2018;9:1358
Frontiers in physiology 2018;9:1358
Non-Hematopoietic MLKL Protects Against Salmonella Mucosal Infection by Enhancing Inflammasome Activation.
Yu SX, Chen W, Liu ZZ, Zhou FH, Yan SQ, Hu GQ, Qin XX, Zhang J, Ma K, Du CT, Gu JM, Deng XM, Han WY, Yang YJ
Frontiers in immunology 2018;9:119
Frontiers in immunology 2018;9:119
Evaluation of Oral Antiretroviral Drugs in Mice With Metabolic and Neurologic Complications.
Tsai FJ, Ho MW, Lai CH, Chou CH, Li JP, Cheng CF, Wu YC, Liu X, Tsang H, Lin TH, Liao CC, Huang SM, Lin JC, Lin CC, Hsieh CL, Liang WM, Lin YJ
Frontiers in pharmacology 2018;9:1004
Frontiers in pharmacology 2018;9:1004
Efficient delivery of nucleic acid molecules into skin by combined use of microneedle roller and flexible interdigitated electroporation array.
Huang D, Zhao D, Wang X, Li C, Yang T, Du L, Wei Z, Cheng Q, Cao H, Liang Z, Huang Y, Li Z
Theranostics 2018;8(9):2361-2376
Theranostics 2018;8(9):2361-2376
OVOL2 links stemness and metastasis via fine-tuning epithelial-mesenchymal transition in nasopharyngeal carcinoma.
Qi XK, Han HQ, Zhang HJ, Xu M, Li L, Chen L, Xiang T, Feng QS, Kang T, Qian CN, Cai MY, Tao Q, Zeng YX, Feng L
Theranostics 2018;8(8):2202-2216
Theranostics 2018;8(8):2202-2216
S6K1 phosphorylation-dependent degradation of Mxi1 by β-Trcp ubiquitin ligase promotes Myc activation and radioresistance in lung cancer.
Huang Y, Hu K, Zhang S, Dong X, Yin Z, Meng R, Zhao Y, Dai X, Zhang T, Yang K, Liu L, Huang K, Shi S, Zhang Y, Chen J, Wu G, Xu S
Theranostics 2018;8(5):1286-1300
Theranostics 2018;8(5):1286-1300
Long noncoding RNA CCAT2 is activated by E2F1 and exerts oncogenic properties by interacting with PTTG1 in pituitary adenomas.
Fu D, Zhang Y, Cui H
American journal of cancer research 2018;8(2):245-255
American journal of cancer research 2018;8(2):245-255
Dengue Virus Infects Primary Human Hair Follicle Dermal Papilla Cells.
Wei KC, Huang MS, Chang TH
Frontiers in cellular and infection microbiology 2018;8:268
Frontiers in cellular and infection microbiology 2018;8:268
Neurodegeneration-associated FUS is a novel regulator of circadian gene expression.
Jiang X, Zhang T, Wang H, Wang T, Qin M, Bao P, Wang R, Liu Y, Chang HC, Yan J, Xu J
Translational neurodegeneration 2018;7:24
Translational neurodegeneration 2018;7:24
Does the Genetic Feature of the Chinese Tree Shrew (Tupaia belangeri chinensis) Support Its Potential as a Viable Model for Alzheimer's Disease Research?
Fan Y, Luo R, Su LY, Xiang Q, Yu D, Xu L, Chen JQ, Bi R, Wu DD, Zheng P, Yao YG
Journal of Alzheimer's disease : JAD 2018;61(3):1015-1028
Journal of Alzheimer's disease : JAD 2018;61(3):1015-1028
Huperzine A attenuates nonalcoholic fatty liver disease by regulating hepatocyte senescence and apoptosis: an in vitro study.
Hu XN, Wang JF, Huang YQ, Wang Z, Dong FY, Ma HF, Bao ZJ
PeerJ 2018;6:e5145
PeerJ 2018;6:e5145
miRNA-1290 Promotes Aggressiveness in Pancreatic Ductal Adenocarcinoma by Targeting IKK1.
Ta N, Huang X, Zheng K, Zhang Y, Gao Y, Deng L, Zhang B, Jiang H, Zheng J
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;51(2):711-728
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;51(2):711-728
FGFR2 Promotes Gastric Cancer Progression by Inhibiting the Expression of Thrombospondin4 via PI3K-Akt-Mtor Pathway.
Huang T, Liu D, Wang Y, Li P, Sun L, Xiong H, Dai Y, Zou M, Yuan X, Qiu H
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;50(4):1332-1345
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;50(4):1332-1345
Activator Protein-2β Promotes Tumor Growth and Predicts Poor Prognosis in Breast Cancer.
Li Z, Xu X, Luo M, Hao J, Zhao S, Yu W, Xiao X, Wu J, Zheng F, Chen M, Li Y, Qin G, Liao Y, Zhao X, Yu X, Guo W, Zou L, Deng W
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;47(5):1925-1935
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;47(5):1925-1935
HSP70/HSP90-Organizing Protein Contributes to Gastric Cancer Progression in an Autocrine Fashion and Predicts Poor Survival in Gastric Cancer.
Zhai E, Liang W, Lin Y, Huang L, He X, Cai S, Chen J, Zhang N, Li J, Zhang Q, He Y, Zeng Z, Chen M, Xu L, Peng S
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;47(2):879-892
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;47(2):879-892
Asiatic Acid (AA) Sensitizes Multidrug-Resistant Human Lung Adenocarcinoma A549/DDP Cells to Cisplatin (DDP) via Downregulation of P-Glycoprotein (MDR1) and Its Targets.
Cheng Q, Liao M, Hu H, Li H, Wu L
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;47(1):279-292
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;47(1):279-292
17β-Estradiol inhibits intervertebral disc degeneration by down-regulating MMP-3 and MMP-13 and up-regulating type II collagen in a rat model.
Liu S, Yang SD, Huo XW, Yang DL, Ma L, Ding WY
Artificial cells, nanomedicine, and biotechnology 2018;46(sup2):182-191
Artificial cells, nanomedicine, and biotechnology 2018;46(sup2):182-191
Neuroprotective Effects of Magnesium Lithospermate B against Subarachnoid Hemorrhage in Rats.
Peng Y, He P, Fan L, Xu H, Li J, Chen T, Ruan W, Dou Z, Chen G
The American journal of Chinese medicine 2018;46(6):1225-1241
The American journal of Chinese medicine 2018;46(6):1225-1241
NR4A1 is Involved in Fibrogenesis in Ovarian Endometriosis.
Zeng X, Yue Z, Gao Y, Jiang G, Zeng F, Shao Y, Huang J, Yin M, Li Y
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;46(3):1078-1090
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;46(3):1078-1090
Ethyl Pyruvate Attenuates CaCl2-Induced Tubular Epithelial Cell Injury by Inhibiting Autophagy and Inflammatory Responses.
Zhao J, Cheng J, Li C, Xu M, Ma C, Qin L, Yi K, Liao N
Kidney & blood pressure research 2018;43(5):1585-1595
Kidney & blood pressure research 2018;43(5):1585-1595
Inhibition of Autophagy Attenuated Ethylene Glycol Induced Crystals Deposition and Renal Injury in a Rat Model of Nephrolithiasis.
Liu Y, Liu Q, Wang X, He Z, Li D, Guan X, Tao Z, Deng Y
Kidney & blood pressure research 2018;43(1):246-255
Kidney & blood pressure research 2018;43(1):246-255
Renal sympathetic denervation lowers arterial pressure in canines with obesity-induced hypertension by regulating GAD65 and AT(1)R expression in rostral ventrolateral medulla.
Shen Z, Weng C, Zhang Z, Wang X, Yang K
Clinical and experimental hypertension (New York, N.Y. : 1993) 2018;40(1):49-57
Clinical and experimental hypertension (New York, N.Y. : 1993) 2018;40(1):49-57
MST1 Suppression Reduces Early Brain Injury by Inhibiting the NF-κB/MMP-9 Pathway after Subarachnoid Hemorrhage in Mice.
Qu J, Zhao H, Li Q, Pan P, Ma K, Liu X, Feng H, Chen Y
Behavioural neurology 2018;2018:6470957
Behavioural neurology 2018;2018:6470957
Hypoxia Enhances Fusion of Oral Squamous Carcinoma Cells and Epithelial Cells Partly via the Epithelial-Mesenchymal Transition of Epithelial Cells.
Huang CM, Yan TL, Xu Z, Wang M, Zhou XC, Jiang EH, Liu K, Shao Z, Shang ZJ
BioMed research international 2018;2018:5015203
BioMed research international 2018;2018:5015203
Increased Autophagy Enhances the Resistance to Tumor Necrosis Factor-Alpha Treatment in Rheumatoid Arthritis Human Fibroblast-Like Synovial Cell.
Dai Y, Ding J, Yin W, He Y, Yu F, Ye C, Hu S, Yu Y
BioMed research international 2018;2018:4941027
BioMed research international 2018;2018:4941027
Hydrogen Sulfide Alleviates Acute Myocardial Ischemia Injury by Modulating Autophagy and Inflammation Response under Oxidative Stress.
Bai YD, Yang YR, Mu XP, Lin G, Wang YP, Jin S, Chen Y, Wang MJ, Zhu YC
Oxidative medicine and cellular longevity 2018;2018:3402809
Oxidative medicine and cellular longevity 2018;2018:3402809
3-(1H-Benzo[d]imidazol-6-yl)-5-(4-fluorophenyl)-1,2,4-oxadiazole (DDO7232), a Novel Potent Nrf2/ARE Inducer, Ameliorates DSS-Induced Murine Colitis and Protects NCM460 Cells against Oxidative Stress via ERK1/2 Phosphorylation.
Xu LL, Liu T, Wang L, Li L, Wu YF, Li CC, Di B, You QD, Jiang ZY
Oxidative medicine and cellular longevity 2018;2018:3271617
Oxidative medicine and cellular longevity 2018;2018:3271617
High Expression of ITGA3 Promotes Proliferation and Cell Cycle Progression and Indicates Poor Prognosis in Intrahepatic Cholangiocarcinoma.
Huang Y, Kong Y, Zhang L, He T, Zhou X, Yan Y, Zhang L, Zhou D, Lu S, Zhou J, Zhou L, Xie H, Zheng S, Wang W
BioMed research international 2018;2018:2352139
BioMed research international 2018;2018:2352139
Selenoprotein S Attenuates Tumor Necrosis Factor-α-Induced Dysfunction in Endothelial Cells.
Cui S, Men L, Li Y, Zhong Y, Yu S, Li F, Du J
Mediators of inflammation 2018;2018:1625414
Mediators of inflammation 2018;2018:1625414
RNF138 confers cisplatin resistance in gastric cancer cells via activating Chk1 signaling pathway.
Lu Y, Han D, Liu W, Huang R, Ou J, Chen X, Zhang X, Wang X, Li S, Wang L, Liu C, Miao S, Wang L, Ma C, Song W
Cancer biology & therapy 2018;19(12):1128-1138
Cancer biology & therapy 2018;19(12):1128-1138
MicroRNA-133b/EGFR axis regulates esophageal squamous cell carcinoma metastases by suppressing anoikis resistance and anchorage-independent growth.
Zhu JF, Liu Y, Huang H, Shan L, Han ZG, Liu JY, Li YL, Dong X, Zeng W
Cancer cell international 2018;18:193
Cancer cell international 2018;18:193
Paraoxonase 3 is involved in the multi-drug resistance of esophageal cancer.
Huang D, Wang Y, He Y, Wang G, Wang W, Han X, Sun Y, Lin L, Shan B, Shen G, Cheng M, Bian G, Fang X, Hu S, Pan Y
Cancer cell international 2018;18:168
Cancer cell international 2018;18:168
The lncRNA CCAT1 upregulates TGFβR1 via sponging miR-490-3p to promote TGFβ1-induced EMT of ovarian cancer cells.
Mu Y, Li N, Cui YL
Cancer cell international 2018;18:145
Cancer cell international 2018;18:145
Downregulation of MiR-203a Disinhibits Bmi1 and Promotes Growth and Proliferation of Keratinocytes in Cholesteatoma.
Zang J, Hui L, Yang N, Yang B, Jiang X
International journal of medical sciences 2018;15(5):447-455
International journal of medical sciences 2018;15(5):447-455
Amelioration of hepatic steatosis is associated with modulation of gut microbiota and suppression of hepatic miR-34a in Gynostemma pentaphylla (Thunb.) Makino treated mice.
Jia N, Lin X, Ma S, Ge S, Mu S, Yang C, Shi S, Gao L, Xu J, Bo T, Zhao J
Nutrition & metabolism 2018;15:86
Nutrition & metabolism 2018;15:86
Overexpression of Toll-like Receptor 4-linked Mitogen-activated Protein Kinase Signaling Contributes to Internalization of Escherichia coli in Sheep.
Wang S, Cao Y, Deng S, Jiang X, Wang J, Zhang X, Zhang J, Liu G, Lian Z
International journal of biological sciences 2018;14(9):1022-1032
International journal of biological sciences 2018;14(9):1022-1032
PARI functions as a new transcriptional target of FOXM1 involved in gastric cancer development.
Zhang Y, Ye X, Chen L, Wu Q, Gao Y, Li Y
International journal of biological sciences 2018;14(5):531-541
International journal of biological sciences 2018;14(5):531-541
Engagement of circular RNA HECW2 in the nonautophagic role of ATG5 implicated in the endothelial-mesenchymal transition.
Yang L, Han B, Zhang Y, Bai Y, Chao J, Hu G, Yao H
Autophagy 2018;14(3):404-418
Autophagy 2018;14(3):404-418
Autosomal dominant retinitis pigmentosa-associated gene PRPF8 is essential for hypoxia-induced mitophagy through regulating ULK1 mRNA splicing.
Xu G, Li T, Chen J, Li C, Zhao H, Yao C, Dong H, Wen K, Wang K, Zhao J, Xia Q, Zhou T, Zhang H, Gao P, Li A, Pan X
Autophagy 2018;14(10):1818-1830
Autophagy 2018;14(10):1818-1830
Combined inhibition of autophagy and Nrf2 signaling augments bortezomib-induced apoptosis by increasing ROS production and ER stress in pancreatic cancer cells.
Li X, Liang M, Jiang J, He R, Wang M, Guo X, Shen M, Qin R
International journal of biological sciences 2018;14(10):1291-1305
International journal of biological sciences 2018;14(10):1291-1305
Dexmedetomidine attenuates the propofol-induced long-term neurotoxicity in the developing brain of rats by enhancing the PI3K/Akt signaling pathway.
Xiao Y, Zhou L, Tu Y, Li Y, Liang Y, Zhang X, Lv J, Zhong Y, Xie Y
Neuropsychiatric disease and treatment 2018;14:2191-2206
Neuropsychiatric disease and treatment 2018;14:2191-2206
Wenyang Huazhuo Tongluo formula inhibits fibrosis via suppressing Wnt/β-catenin signaling pathway in a Bleomycin-induced systemic sclerosis mouse model.
Wang Q, Zang W, Han L, Yang L, Ye S, Ouyang J, Zhang C, Bi Y, Zhang C, Bian H
Chinese medicine 2018;13:17
Chinese medicine 2018;13:17
Notch inhibitor can attenuate apparent diffusion coefficient and improve neurological function through downregulating NOX2-ROS in severe traumatic brain injury.
Zhang HM, Chen W, Liu RN, Zhao Y
Drug design, development and therapy 2018;12:3847-3854
Drug design, development and therapy 2018;12:3847-3854
Realgar, a traditional Chinese medicine, induces apoptosis of HPV16-positive cervical cells through a HPV16 E7-related pathway.
Ding W, Ji T, Xiong W, Li T, Pu D, Liu R
Drug design, development and therapy 2018;12:3459-3469
Drug design, development and therapy 2018;12:3459-3469
Zoledronate inhibits fibroblasts' proliferation and activation via targeting TGF-β signaling pathway.
Zhao Z, Shen W, Zhu H, Lin L, Jiang G, Zhu Y, Song H, Wu L
Drug design, development and therapy 2018;12:3021-3031
Drug design, development and therapy 2018;12:3021-3031
Gestational Exposure to Particulate Matter 2.5 (PM(2.5)) Leads to Spatial Memory Dysfunction and Neurodevelopmental Impairment in Hippocampus of Mice Offspring.
Zheng X, Wang X, Wang T, Zhang H, Wu H, Zhang C, Yu L, Guan Y
Frontiers in neuroscience 2018;12:1000
Frontiers in neuroscience 2018;12:1000
EDIL3 depletion suppress epithelial-mesenchymal transition of lens epithelial cells via transforming growth factor β pathway.
Zhang R, Wei YH, Zhao CY, Song HY, Shen N, Cui X, Gao X, Qi ZT, Zhong M, Shen W
International journal of ophthalmology 2018;11(1):18-24
International journal of ophthalmology 2018;11(1):18-24
Endothelial Monocyte-Activating Polypeptide-II Induces BNIP3-Mediated Mitophagy to Enhance Temozolomide Cytotoxicity of Glioma Stem Cells via Down-Regulating MiR-24-3p.
Zhang J, Liu L, Xue Y, Ma Y, Liu X, Li Z, Li Z, Liu Y
Frontiers in molecular neuroscience 2018;11:92
Frontiers in molecular neuroscience 2018;11:92
Brevilin A promotes oxidative stress and induces mitochondrial apoptosis in U87 glioblastoma cells.
Wang J, Li M, Cui X, Lv D, Jin L, Khan M, Ma T
OncoTargets and therapy 2018;11:7031-7040
OncoTargets and therapy 2018;11:7031-7040
MiR-429 Regulated by Endothelial Monocyte Activating Polypeptide-II (EMAP-II) Influences Blood-Tumor Barrier Permeability by Inhibiting the Expressions of ZO-1, Occludin and Claudin-5.
Chen L, Xue Y, Zheng J, Liu X, Liu J, Chen J, Li Z, Xi Z, Teng H, Wang P, Liu L, Liu Y
Frontiers in molecular neuroscience 2018;11:35
Frontiers in molecular neuroscience 2018;11:35
STAT3 induces colorectal carcinoma progression through a novel miR-572-MOAP-1 pathway.
Wang N, He X, Zhou R, Jia G, Qiao Q
OncoTargets and therapy 2018;11:3475-3484
OncoTargets and therapy 2018;11:3475-3484
Hypoxic Preconditioning Maintains GLT-1 Against Transient Global Cerebral Ischemia Through Upregulating Cx43 and Inhibiting c-Src.
Li K, Zhou H, Zhan L, Shi Z, Sun W, Liu D, Liu L, Liang D, Tan Y, Xu W, Xu E
Frontiers in molecular neuroscience 2018;11:344
Frontiers in molecular neuroscience 2018;11:344
Cosmosiin Increases ADAM10 Expression via Mechanisms Involving 5'UTR and PI3K Signaling.
Min Z, Tang Y, Hu XT, Zhu BL, Ma YL, Zha JS, Deng XJ, Yan Z, Chen GJ
Frontiers in molecular neuroscience 2018;11:198
Frontiers in molecular neuroscience 2018;11:198
Transcriptional Repression of p53 by PAX3 Contributes to Gliomagenesis and Differentiation of Glioma Stem Cells.
Zhu H, Wang H, Huang Q, Liu Q, Guo Y, Lu J, Li X, Xue C, Han Q
Frontiers in molecular neuroscience 2018;11:187
Frontiers in molecular neuroscience 2018;11:187
Characteristics of Sinus Fungus Ball: A Unique Form of Rhinosinusitis.
Jiang RS, Huang WC, Liang KL
Clinical medicine insights. Ear, nose and throat 2018;11:1179550618792254
Clinical medicine insights. Ear, nose and throat 2018;11:1179550618792254
GPX3 suppresses tumor migration and invasion via the FAK/AKT pathway in esophageal squamous cell carcinoma.
Zhu X, Wang J, Li L, Deng L, Wang J, Liu L, Zeng R, Wang Q, Zheng Y
American journal of translational research 2018;10(6):1908-1920
American journal of translational research 2018;10(6):1908-1920
NADH protect against radiation enteritis by enhancing autophagy and inhibiting inflammation through PI3K/AKT pathway.
Wang JT, Xie WQ, Liu FQ, Bi Y, Zhu XJ, Wang QE, Zheng YF
American journal of translational research 2018;10(6):1713-1721
American journal of translational research 2018;10(6):1713-1721
Reduced selenium-binding protein 1 correlates with a poor prognosis in intrahepatic cholangiocarcinoma and promotes the cell epithelial-mesenchymal transition.
Zhang XY, Gao PT, Yang X, Cai JB, Ding GY, Zhu XD, Ji Y, Shi GM, Shen YH, Zhou J, Fan J, Sun HC, Yang LX, Huang C
American journal of translational research 2018;10(11):3567-3578
American journal of translational research 2018;10(11):3567-3578
miR-125a-5p suppresses colorectal cancer progression by targeting VEGFA.
Yang X, Qiu J, Kang H, Wang Y, Qian J
Cancer management and research 2018;10:5839-5853
Cancer management and research 2018;10:5839-5853
Non-coding RNA NEAT1/miR-214-3p contribute to doxorubicin resistance of urothelial bladder cancer preliminary through the Wnt/β-catenin pathway.
Guo Y, Zhang H, Xie D, Hu X, Song R, Zhu L
Cancer management and research 2018;10:4371-4380
Cancer management and research 2018;10:4371-4380
Inhibition of Cathepsins B Induces Neuroprotection Against Secondary Degeneration in Ipsilateral Substantia Nigra After Focal Cortical Infarction in Adult Male Rats.
Zuo X, Hou Q, Jin J, Chen X, Zhan L, Tang Y, Shi Z, Sun W, Xu E
Frontiers in aging neuroscience 2018;10:125
Frontiers in aging neuroscience 2018;10:125
The transcription factor C/EBP α controls the role of cystatin F during the differentiation of monocytes to macrophages.
Dautović E, Perišić Nanut M, Softić A, Kos J
European journal of cell biology 2018 Sep;97(7):463-473
European journal of cell biology 2018 Sep;97(7):463-473
Comparative proteomics reveals the neurotoxicity mechanism of ER stressors tunicamycin and dithiothreitol.
Ren B, Wang Y, Wang H, Wu Y, Li J, Tian J
Neurotoxicology 2018 Sep;68:25-37
Neurotoxicology 2018 Sep;68:25-37
Gemcitabine induces apoptosis and autophagy via the AMPK/mTOR signaling pathway in pancreatic cancer cells.
Zhu J, Chen Y, Ji Y, Yu Y, Jin Y, Zhang X, Zhou J
Biotechnology and applied biochemistry 2018 Sep;65(5):665-671
Biotechnology and applied biochemistry 2018 Sep;65(5):665-671
Sex differences in the effect of cannabinoid type 1 receptor deletion on locus coeruleus-norepinephrine neurons and corticotropin releasing factor-mediated responses.
Wyrofsky RR, Reyes BAS, Yu D, Kirby LG, Van Bockstaele EJ
The European journal of neuroscience 2018 Sep;48(5):2118-2138
The European journal of neuroscience 2018 Sep;48(5):2118-2138
The suppressive effect of soluble Klotho on fibroblastic growth factor 23 synthesis in UMR-106 osteoblast-like cells.
Ma L, Gao M, Wu L, Zhao X, Mao H, Xing C
Cell biology international 2018 Sep;42(9):1270-1274
Cell biology international 2018 Sep;42(9):1270-1274
Downregulation of TRIM58 expression is associated with a poor patient outcome and enhances colorectal cancer cell invasion.
Liu M, Zhang X, Cai J, Li Y, Luo Q, Wu H, Yang Z, Wang L, Chen D
Oncology reports 2018 Sep;40(3):1251-1260
Oncology reports 2018 Sep;40(3):1251-1260
Interferon Gamma Inhibits CXCL8-Induced Proliferation and Migration of Pancreatic Cancer BxPC-3 Cell Line via a RhoGDI2/Rac1/NF-κB Signaling Pathway.
Zhang M, Ding G, Zhou L, Shen T, Xu X, Zhao T, Jia S, Cao L
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 2018 Sep;38(9):413-422
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 2018 Sep;38(9):413-422
Selective Actionable and Druggable Protein Kinases Drive the Progression of Neuroendocrine Prostate Cancer.
Lu C, Qie Y, Liu S, Wu C, Zhang Z, Liu R, Yang K, Hu H, Xu Y
DNA and cell biology 2018 Sep;37(9):758-766
DNA and cell biology 2018 Sep;37(9):758-766
Activation of STAT3 and Bcl-2 and reduction of reactive oxygen species (ROS) promote radioresistance in breast cancer and overcome of radioresistance with niclosamide.
Lu L, Dong J, Wang L, Xia Q, Zhang D, Kim H, Yin T, Fan S, Shen Q
Oncogene 2018 Sep;37(39):5292-5304
Oncogene 2018 Sep;37(39):5292-5304
IL-6 increases podocyte motility via MLC-mediated focal adhesion impairment and cytoskeleton disassembly.
He FF, Bao D, Su H, Wang YM, Lei CT, Zhang CY, Ye C, Tang H, Wan C, You CQ, Zhang J, Xiong J, Zhang C
Journal of cellular physiology 2018 Sep;233(9):7173-7181
Journal of cellular physiology 2018 Sep;233(9):7173-7181
Epigenetic regulation of megakaryocytic and erythroid differentiation by PHF2 histone demethylase.
Yang J, Ma J, Xiong Y, Wang Y, Jin K, Xia W, Chen Q, Huang J, Zhang J, Jiang N, Jiang S, Ma D
Journal of cellular physiology 2018 Sep;233(9):6841-6852
Journal of cellular physiology 2018 Sep;233(9):6841-6852
The oncogenic potentials and diagnostic significance of long non-coding RNA LINC00310 in breast cancer.
Li J, Peng W, Du L, Yang Q, Wang C, Mo YY
Journal of cellular and molecular medicine 2018 Sep;22(9):4486-4495
Journal of cellular and molecular medicine 2018 Sep;22(9):4486-4495
Stromal expression of JNK1 and VDR is associated with the prognosis of esophageal squamous cell carcinoma.
Bao Y, Zhang S, Guo Y, Wei X, Zhang Y, Yang Y, Zhang H, Ma M, Yang W
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 2018 Sep;20(9):1185-1195
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 2018 Sep;20(9):1185-1195
Protein arginine methyltransferase 5-mediated epigenetic silencing of IRX1 contributes to tumorigenicity and metastasis of gastric cancer.
Liu X, Zhang J, Liu L, Jiang Y, Ji J, Yan R, Zhu Z, Yu Y
Biochimica et biophysica acta. Molecular basis of disease 2018 Sep;1864(9 Pt B):2835-2844
Biochimica et biophysica acta. Molecular basis of disease 2018 Sep;1864(9 Pt B):2835-2844
UNBS5162 inhibits proliferation of human melanoma cells by inducing apoptosis via the PI3K/Akt pathway.
Shi X, Yang L, Xie J, Zhao Y, Cong J, Li Z, Li H, Cheng X, Fan J
Molecular medicine reports 2018 Sep;18(3):3382-3388
Molecular medicine reports 2018 Sep;18(3):3382-3388
Adenoviral vector-induced silencing of RGMa attenuates blood-brain barrier dysfunction in a rat model of MCAO/reperfusion.
Li M, Wen Y, Zhang R, Xie F, Zhang G, Qin X
Brain research bulletin 2018 Sep;142:54-62
Brain research bulletin 2018 Sep;142:54-62
Role of hepatoma-derived growth factor in promoting de novo lipogenesis and tumorigenesis in hepatocellular carcinoma.
Min X, Wen J, Zhao L, Wang K, Li Q, Huang G, Liu J, Zhao X
Molecular oncology 2018 Sep;12(9):1480-1497
Molecular oncology 2018 Sep;12(9):1480-1497
Long noncoding RNA LINC00460 targets miR-539/MMP-9 to promote meningioma progression and metastasis.
Xing H, Wang S, Li Q, Ma Y, Sun P
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Sep;105:677-682
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Sep;105:677-682
USP4 positively regulates RLR-induced NF-κB activation by targeting TRAF6 for K48-linked deubiquitination and inhibits enterovirus 71 replication.
Xu C, Peng Y, Zhang Q, Xu XP, Kong XM, Shi WF
Scientific reports 2018 Sep 7;8(1):13418
Scientific reports 2018 Sep 7;8(1):13418
FOXC1 induces cancer stem cell-like properties through upregulation of beta-catenin in NSCLC.
Cao S, Wang Z, Gao X, He W, Cai Y, Chen H, Xu R
Journal of experimental & clinical cancer research : CR 2018 Sep 6;37(1):220
Journal of experimental & clinical cancer research : CR 2018 Sep 6;37(1):220
De Novo Mutations of CCNK Cause a Syndromic Neurodevelopmental Disorder with Distinctive Facial Dysmorphism.
Fan Y, Yin W, Hu B, Kline AD, Zhang VW, Liang D, Sun Y, Wang L, Tang S, Powis Z, Li L, Yan H, Shi Z, Yang X, Chen Y, Wang J, Jiang Y, Tan H, Gu X, Wu L, Yu Y
American journal of human genetics 2018 Sep 6;103(3):448-455
American journal of human genetics 2018 Sep 6;103(3):448-455
LINC00470 Coordinates the Epigenetic Regulation of ELFN2 to Distract GBM Cell Autophagy.
Liu C, Fu H, Liu X, Lei Q, Zhang Y, She X, Liu Q, Liu Q, Sun Y, Li G, Wu M
Molecular therapy : the journal of the American Society of Gene Therapy 2018 Sep 5;26(9):2267-2281
Molecular therapy : the journal of the American Society of Gene Therapy 2018 Sep 5;26(9):2267-2281
Cationic Polymeric Nanoparticle Delivering CCR2 siRNA to Inflammatory Monocytes for Tumor Microenvironment Modification and Cancer Therapy.
Shen S, Zhang Y, Chen KG, Luo YL, Wang J
Molecular pharmaceutics 2018 Sep 4;15(9):3642-3653
Molecular pharmaceutics 2018 Sep 4;15(9):3642-3653
A new meroterpenoid functions as an anti-tumor agent in hepatoma cells by downregulating mTOR activation and inhibiting EMT.
Wan H, Li J, Zhang K, Zou X, Ge L, Zhu F, Zhou H, Gong M, Wang T, Chen D, Peng S, Zhou B, Zeng X
Scientific reports 2018 Sep 3;8(1):13152
Scientific reports 2018 Sep 3;8(1):13152
Long noncoding RNA MIR31HG inhibits hepatocellular carcinoma proliferation and metastasis by sponging microRNA-575 to modulate ST7L expression.
Yan S, Tang Z, Chen K, Liu Y, Yu G, Chen Q, Dang H, Chen F, Ling J, Zhu L, Huang A, Tang H
Journal of experimental & clinical cancer research : CR 2018 Sep 3;37(1):214
Journal of experimental & clinical cancer research : CR 2018 Sep 3;37(1):214
Covalent inhibitors of EGFR family protein kinases induce degradation of human Tribbles 2 (TRIB2) pseudokinase in cancer cells.
Foulkes DM, Byrne DP, Yeung W, Shrestha S, Bailey FP, Ferries S, Eyers CE, Keeshan K, Wells C, Drewry DH, Zuercher WJ, Kannan N, Eyers PA
Science signaling 2018 Sep 25;11(549)
Science signaling 2018 Sep 25;11(549)
Distinct multilevel misregulations of Parkin and PINK1 revealed in cell and animal models of TDP-43 proteinopathy.
Sun X, Duan Y, Qin C, Li JC, Duan G, Deng X, Ni J, Cao X, Xiang K, Tian K, Chen CH, Li A, Fang Y
Cell death & disease 2018 Sep 20;9(10):953
Cell death & disease 2018 Sep 20;9(10):953
Targeting Epigenetic Crosstalk as a Therapeutic Strategy for EZH2-Aberrant Solid Tumors.
Huang X, Yan J, Zhang M, Wang Y, Chen Y, Fu X, Wei R, Zheng XL, Liu Z, Zhang X, Yang H, Hao B, Shen YY, Su Y, Cong X, Huang M, Tan M, Ding J, Geng M
Cell 2018 Sep 20;175(1):186-199.e19
Cell 2018 Sep 20;175(1):186-199.e19
Anti-breast-Cancer Activity Exerted by β-Sitosterol-d-glucoside from Sweet Potato via Upregulation of MicroRNA-10a and via the PI3K-Akt Signaling Pathway.
Xu H, Li Y, Han B, Li Z, Wang B, Jiang P, Zhang J, Ma W, Zhou D, Li X, Ye X
Journal of agricultural and food chemistry 2018 Sep 19;66(37):9704-9718
Journal of agricultural and food chemistry 2018 Sep 19;66(37):9704-9718
Postinfarction Hearts Are Protected by Premature Senescent Cardiomyocytes Via GATA 4-Dependent CCN 1 Secretion.
Cui S, Xue L, Yang F, Dai S, Han Z, Liu K, Liu B, Yuan Q, Cui Z, Zhang Y, Xu F, Chen Y
Journal of the American Heart Association 2018 Sep 18;7(18):e009111
Journal of the American Heart Association 2018 Sep 18;7(18):e009111
IL-13 and IL-13Rα1 are overexpressed in extranodal natural killer/T cell lymphoma and mediate tumor cell proliferation.
Zhang Y, Li C, Zhang M, Li Z
Biochemical and biophysical research communications 2018 Sep 18;503(4):2715-2720
Biochemical and biophysical research communications 2018 Sep 18;503(4):2715-2720
Non-canonical NF-κB Antagonizes STING Sensor-Mediated DNA Sensing in Radiotherapy.
Hou Y, Liang H, Rao E, Zheng W, Huang X, Deng L, Zhang Y, Yu X, Xu M, Mauceri H, Arina A, Weichselbaum RR, Fu YX
Immunity 2018 Sep 18;49(3):490-503.e4
Immunity 2018 Sep 18;49(3):490-503.e4
Mesenchymal stem cells alleviate experimental autoimmune cholangitis through immunosuppression and cytoprotective function mediated by galectin-9.
Fan J, Tang X, Wang Q, Zhang Z, Wu S, Li W, Liu S, Yao G, Chen H, Sun L
Stem cell research & therapy 2018 Sep 17;9(1):237
Stem cell research & therapy 2018 Sep 17;9(1):237
TPC2 mediates autophagy progression and extracellular vesicle secretion in cancer cells.
Sun W, Yue J
Experimental cell research 2018 Sep 15;370(2):478-489
Experimental cell research 2018 Sep 15;370(2):478-489
Rab7 empowers renal tubular epithelial cells with autophagy-mediated protection against albumin-induced injury.
Liu L, Li Y, Wang Z, Ding F, Cheng Z, Xu Q, Cai Y, Limbu MH, Yang Y, Liu B, Chen P
Experimental cell research 2018 Sep 15;370(2):198-207
Experimental cell research 2018 Sep 15;370(2):198-207
miR-203 Suppresses Bladder Cancer Cell Growth and Targets Twist1.
Shen J, Zhang J, Xiao M, Yang J, Zhang N
Oncology research 2018 Sep 14;26(8):1155-1165
Oncology research 2018 Sep 14;26(8):1155-1165
Human Cytomegalovirus Immediate Early 1 Protein Causes Loss of SOX2 from Neural Progenitor Cells by Trapping Unphosphorylated STAT3 in the Nucleus.
Wu CC, Jiang X, Wang XZ, Liu XJ, Li XJ, Yang B, Ye HQ, Harwardt T, Jiang M, Xia HM, Wang W, Britt WJ, Paulus C, Nevels M, Luo MH
Journal of virology 2018 Sep 1;92(17)
Journal of virology 2018 Sep 1;92(17)
The developmental transcription factor IRF6 attenuates ABCG2 gene expression and distinctively reverses stemness phenotype in nasopharyngeal carcinoma.
Xu L, Huang TJ, Hu H, Wang MY, Shi SM, Yang Q, Lin F, Qiang YY, Mei Y, Lang YH, Li CZ, Peng LX, Zheng LS, Huang JL, Li XJ, Zhang SJ, Qian CN, Huang BJ
Cancer letters 2018 Sep 1;431:230-243
Cancer letters 2018 Sep 1;431:230-243
Spinal interleukin-10 produces antinociception in neuropathy through microglial β-endorphin expression, separated from antineuroinflammation.
Wu HY, Mao XF, Tang XQ, Ali U, Apryani E, Liu H, Li XY, Wang YX
Brain, behavior, and immunity 2018 Oct;73:504-519
Brain, behavior, and immunity 2018 Oct;73:504-519
MALAT1 promotes the colorectal cancer malignancy by increasing DCP1A expression and miR203 downregulation.
Wu C, Zhu X, Tao K, Liu W, Ruan T, Wan W, Zhang C, Zhang W
Molecular carcinogenesis 2018 Oct;57(10):1421-1431
Molecular carcinogenesis 2018 Oct;57(10):1421-1431
MiR-616-3p modulates cell proliferation and migration through targeting tissue factor pathway inhibitor 2 in preeclampsia.
Xu Y, Wu D, Jiang Z, Zhang Y, Wang S, Ma Z, Hui B, Wang J, Qian W, Ge Z, Sun L
Cell proliferation 2018 Oct;51(5):e12490
Cell proliferation 2018 Oct;51(5):e12490
The effects of HAP and macrophage cells to the expression of inflammatory factors and apoptosis in HK-2 cells of vitro co-cultured system.
Yu J, Deng Y, Tao Z, Liang W, Guan X, Wu J, Ning X, Liu Y, Liu Q, He Z
Urolithiasis 2018 Oct;46(5):429-443
Urolithiasis 2018 Oct;46(5):429-443
Effects of NMDAR Antagonist on the Regulation of P-MARCKS Protein to Aβ(1-42) Oligomers Induced Neurotoxicity.
Liu Y, Zhang P, Zheng Y, Yang C, Du T, Ge M, Chang X, Duan R, Ma G
Neurochemical research 2018 Oct;43(10):2008-2015
Neurochemical research 2018 Oct;43(10):2008-2015
GPR40 modulates epileptic seizure and NMDA receptor function.
Yang Y, Tian X, Xu D, Zheng F, Lu X, Zhang Y, Ma Y, Li Y, Xu X, Zhu B, Wang X
Science advances 2018 Oct;4(10):eaau2357
Science advances 2018 Oct;4(10):eaau2357
Erythropoietin-producing hepatocellular A7 triggering ovulation indicates a potential beneficial role for polycystic ovary syndrome.
Li S, Zhai J, Liu J, Di F, Sun Y, Li W, Chen ZJ, Du Y
EBioMedicine 2018 Oct;36:539-552
EBioMedicine 2018 Oct;36:539-552
SIRT5 deacylates metabolism-related proteins and attenuates hepatic steatosis in ob/ob mice.
Du Y, Hu H, Qu S, Wang J, Hua C, Zhang J, Wei P, He X, Hao J, Liu P, Yang F, Li T, Wei T
EBioMedicine 2018 Oct;36:347-357
EBioMedicine 2018 Oct;36:347-357
miR-25 Promotes Melanoma Progression by regulating RNA binding motif protein 47.
Jiang QQ, Liu WB
Medecine sciences : M/S 2018 Oct;34 Focus issue F1:59-65
Medecine sciences : M/S 2018 Oct;34 Focus issue F1:59-65
Histone Deacetylase 3 Inhibitor Suppresses Hepatitis C Virus Replication by Regulating Apo-A1 and LEAP-1 Expression.
Zhou Y, Wang Q, Yang Q, Tang J, Xu C, Gai D, Chen X, Chen J
Virologica Sinica 2018 Oct;33(5):418-428
Virologica Sinica 2018 Oct;33(5):418-428
Histone deacetylase inhibitor suberoylanilide hydroxamic acid alleviates liver fibrosis by suppressing the transforming growth factor-β1 signal pathway.
Wang Y, Zhao L, Jiao FZ, Zhang WB, Chen Q, Gong ZJ
Hepatobiliary & pancreatic diseases international : HBPD INT 2018 Oct;17(5):423-429
Hepatobiliary & pancreatic diseases international : HBPD INT 2018 Oct;17(5):423-429
Study on the expression of p53 and MMP-2 in patients with lung cancer after interventional therapy.
Zhang XS, Wang KY, Gao JQ, Li RJ, Guan QB, Song L
Oncology letters 2018 Oct;16(4):4291-4296
Oncology letters 2018 Oct;16(4):4291-4296
Subarachnoid hemorrhage enhances the expression of TDP-43 in the brain of experimental rats and human subjects.
He T, Zuo Y, Ai-Zakwani K, Luo J, Zhu H, Yan XX, Liu F
Experimental and therapeutic medicine 2018 Oct;16(4):3363-3368
Experimental and therapeutic medicine 2018 Oct;16(4):3363-3368
Genistein sensitizes glioblastoma cells to carbon ions via inhibiting DNA-PKcs phosphorylation and subsequently repressing NHEJ and delaying HR repair pathways.
Liu X, Li P, Hirayama R, Niu Y, Liu X, Chen W, Jin X, Zhang P, Ye F, Zhao T, Liu B, Li Q
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 2018 Oct;129(1):84-94
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 2018 Oct;129(1):84-94
MicroRNA-23a-5p promotes atherosclerotic plaque progression and vulnerability by repressing ATP-binding cassette transporter A1/G1 in macrophages.
Yang S, Ye ZM, Chen S, Luo XY, Chen SL, Mao L, Li Y, Jin H, Yu C, Xiang FX, Xie MX, Chang J, Xia YP, Hu B
Journal of molecular and cellular cardiology 2018 Oct;123:139-149
Journal of molecular and cellular cardiology 2018 Oct;123:139-149
Long non-coding RNA LINC00222 regulates GSK3β activity and promotes cell apoptosis in lung adenocarcinoma.
Zhang H, Wang Y, Lu J, Zhao Y
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Oct;106:755-762
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Oct;106:755-762
MicroRNA-139-3p regulates osteoblast differentiation and apoptosis by targeting ELK1 and interacting with long noncoding RNA ODSM.
Wang Y, Wang K, Hu Z, Zhou H, Zhang L, Wang H, Li G, Zhang S, Cao X, Shi F
Cell death & disease 2018 Oct 31;9(11):1107
Cell death & disease 2018 Oct 31;9(11):1107
The effects of lncRNA MALAT1 on proliferation, invasion and migration in colorectal cancer through regulating SOX9.
Xu Y, Zhang X, Hu X, Zhou W, Zhang P, Zhang J, Yang S, Liu Y
Molecular medicine (Cambridge, Mass.) 2018 Oct 3;24(1):52
Molecular medicine (Cambridge, Mass.) 2018 Oct 3;24(1):52
Apigenin suppresses PD-L1 expression in melanoma and host dendritic cells to elicit synergistic therapeutic effects.
Xu L, Zhang Y, Tian K, Chen X, Zhang R, Mu X, Wu Y, Wang D, Wang S, Liu F, Wang T, Zhang J, Liu S, Zhang Y, Tu C, Liu H
Journal of experimental & clinical cancer research : CR 2018 Oct 29;37(1):261
Journal of experimental & clinical cancer research : CR 2018 Oct 29;37(1):261
Salvianolic Acid B-Alleviated Angiotensin II Induces Cardiac Fibrosis by Suppressing NF-κB Pathway In Vitro.
Wang C, Luo H, Xu Y, Tao L, Chang C, Shen X
Medical science monitor : international medical journal of experimental and clinical research 2018 Oct 26;24:7654-7664
Medical science monitor : international medical journal of experimental and clinical research 2018 Oct 26;24:7654-7664
MicroRNA-9 modified bone marrow-derived mesenchymal stem cells (BMSCs) repair severe acute pancreatitis (SAP) via inducing angiogenesis in rats.
Qian D, Song G, Ma Z, Wang G, Jin L, Hu M, Song Z, Wang X
Stem cell research & therapy 2018 Oct 25;9(1):282
Stem cell research & therapy 2018 Oct 25;9(1):282
Up-regulated miR-133a orchestrates epithelial-mesenchymal transition of airway epithelial cells.
Chen L, He X, Xie Y, Huang Y, Wolff DW, Abel PW, Tu Y
Scientific reports 2018 Oct 19;8(1):15543
Scientific reports 2018 Oct 19;8(1):15543
Neuroinflammation is induced by tongue-instilled ZnO nanoparticles via the Ca(2+)-dependent NF-κB and MAPK pathways.
Liang H, Chen A, Lai X, Liu J, Wu J, Kang Y, Wang X, Shao L
Particle and fibre toxicology 2018 Oct 19;15(1):39
Particle and fibre toxicology 2018 Oct 19;15(1):39
Enhanced anti-obesity effects of bacterial cellulose combined with konjac glucomannan in high-fat diet-fed C57BL/6J mice.
Zhai X, Lin D, Zhao Y, Li W, Yang X
Food & function 2018 Oct 17;9(10):5260-5272
Food & function 2018 Oct 17;9(10):5260-5272
Immune Activation of RAW264.7 Macrophages by Low Molecular Weight Fucoidan Extracted from New Zealand Undaria pinnatifida.
Bi D, Yu B, Han Q, Lu J, White WL, Lai Q, Cai N, Luo W, Gu L, Li S, Xu H, Hu Z, Nie S, Xu X
Journal of agricultural and food chemistry 2018 Oct 17;66(41):10721-10728
Journal of agricultural and food chemistry 2018 Oct 17;66(41):10721-10728
miR-365 Suppresses Cholangiocarcinoma Cell Proliferation and Induces Apoptosis by Targeting E2F2.
Chen L, Huang X, Chen X
Oncology research 2018 Oct 17;26(9):1375-1382
Oncology research 2018 Oct 17;26(9):1375-1382
Cd induces G2/M cell cycle arrest by up-regulating miR-133b via directly targeting PPP2R2D in L02 hepatocytes.
Zhang Y, Xiao F, Zhong C, Zeng M, Zou L
Metallomics : integrated biometal science 2018 Oct 17;10(10):1510-1523
Metallomics : integrated biometal science 2018 Oct 17;10(10):1510-1523
Biased antagonism of CXCR4 avoids antagonist tolerance.
Hitchinson B, Eby JM, Gao X, Guite-Vinet F, Ziarek JJ, Abdelkarim H, Lee Y, Okamoto Y, Shikano S, Majetschak M, Heveker N, Volkman BF, Tarasova NI, Gaponenko V
Science signaling 2018 Oct 16;11(552)
Science signaling 2018 Oct 16;11(552)
GAPDH rs1136666 SNP indicates a high risk of Parkinson's disease.
Ping Z, Xiaomu W, Xufang X, Wenfeng C, Liang S, Tao W
Neuroscience letters 2018 Oct 15;685:55-62
Neuroscience letters 2018 Oct 15;685:55-62
PARP1 interacts with STAT3 and retains active phosphorylated-STAT3 in nucleus during pathological myocardial hypertrophy.
Wang L, Li Z, Tan Y, Li Q, Yang H, Wang P, Lu J, Liu P
Molecular and cellular endocrinology 2018 Oct 15;474:137-150
Molecular and cellular endocrinology 2018 Oct 15;474:137-150
The Age-dependent Elevation of miR-335-3p Leads to Reduced Cholesterol and Impaired Memory in Brain.
Raihan O, Brishti A, Molla MR, Li W, Zhang Q, Xu P, Khan MI, Zhang J, Liu Q
Neuroscience 2018 Oct 15;390:160-173
Neuroscience 2018 Oct 15;390:160-173
Identification of the UBA2-WTIP fusion gene in acute myeloid leukemia.
Lu X, Zhuang H, Yu Q, Zhang X, Wu Z, Zhang L, Xu Y, Wu B, Yang L, Ma A, Gan X, Yu X, Shen J, Xu R
Experimental cell research 2018 Oct 15;371(2):409-416
Experimental cell research 2018 Oct 15;371(2):409-416
Role of p62/SQSTM1 in lipopolysaccharide (LPS)-induced mucus hypersecretion in bronchial epithelial cells.
Wu Y, Li Y, Wang B, He X, Li Y, Wu B, Yu G, Wang H, Xu B
Life sciences 2018 Oct 15;211:270-278
Life sciences 2018 Oct 15;211:270-278
Bowman‒Birk Inhibitor Suppresses Herpes Simplex Virus Type 2 Infection of Human Cervical Epithelial Cells.
Liu Y, Xu XQ, Zhang B, Gu J, Meng FZ, Liu H, Zhou L, Wang X, Hou W, Ho WZ
Viruses 2018 Oct 12;10(10)
Viruses 2018 Oct 12;10(10)
Mechanism of piR-DQ590027/MIR17HG regulating the permeability of glioma conditioned normal BBB.
Leng X, Ma J, Liu Y, Shen S, Yu H, Zheng J, Liu X, Liu L, Chen J, Zhao L, Ruan X, Xue Y
Journal of experimental & clinical cancer research : CR 2018 Oct 11;37(1):246
Journal of experimental & clinical cancer research : CR 2018 Oct 11;37(1):246
Isopsoralen Enhanced Osteogenesis by Targeting AhR/ERα.
Ge L, Cui Y, Cheng K, Han J
Molecules (Basel, Switzerland) 2018 Oct 11;23(10)
Molecules (Basel, Switzerland) 2018 Oct 11;23(10)
Deleting MyD88 signaling in myeloid cells promotes development of adenocarcinomas of the colon.
Song J, Chen Z, Geng T, Wang M, Yi S, Liu K, Zhou W, Gao J, Song W, Tang H
Cancer letters 2018 Oct 1;433:65-75
Cancer letters 2018 Oct 1;433:65-75
Alantolactone induces apoptosis and improves chemosensitivity of pancreatic cancer cells by impairment of autophagy-lysosome pathway via targeting TFEB.
He R, Shi X, Zhou M, Zhao Y, Pan S, Zhao C, Guo X, Wang M, Li X, Qin R
Toxicology and applied pharmacology 2018 Oct 1;356:159-171
Toxicology and applied pharmacology 2018 Oct 1;356:159-171
Regulation of osteogenesis by micro/nano hierarchical titanium surfaces through a Rock-Wnt5a feedback loop.
Yu Y, Shen X, Liu J, Hu Y, Ran Q, Mu C, Cai K
Colloids and surfaces. B, Biointerfaces 2018 Oct 1;170:1-10
Colloids and surfaces. B, Biointerfaces 2018 Oct 1;170:1-10
The protective effect of melatonin on brain ischemia and reperfusion in rats and humans: In vivo assessment and a randomized controlled trial.
Zhao Z, Lu C, Li T, Wang W, Ye W, Zeng R, Ni L, Lai Z, Wang X, Liu C
Journal of pineal research 2018 Nov;65(4):e12521
Journal of pineal research 2018 Nov;65(4):e12521
The sialyltransferase ST3Gal3 facilitates the receptivity of the uterine endometrium in vitro and in vivo.
Yu M, Wang H, Liu J, Qin H, Liu S, Yan Q
FEBS letters 2018 Nov;592(22):3696-3707
FEBS letters 2018 Nov;592(22):3696-3707
RNA interference of long noncoding RNA HOTAIR suppresses autophagy and promotes apoptosis and sensitivity to cisplatin in oral squamous cell carcinoma.
Wang X, Liu W, Wang P, Li S
Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology 2018 Nov;47(10):930-937
Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology 2018 Nov;47(10):930-937
HMGB1 knock-down promoting tumor cells viability and arrest pro-apoptotic proteins via Stat3/NFκB in HepG2 cells.
Alduais S, Alduais Y, Wu X, Li H, Mao J
BioFactors (Oxford, England) 2018 Nov;44(6):570-576
BioFactors (Oxford, England) 2018 Nov;44(6):570-576
KLF5 promotes the tumorigenesis and metastatic potential of thyroid cancer cells through the NF-κB signaling pathway.
Ma Y, Wang Q, Liu F, Ma X, Wu L, Guo F, Zhao S, Huang F, Qin G
Oncology reports 2018 Nov;40(5):2608-2618
Oncology reports 2018 Nov;40(5):2608-2618
Microtubule associated protein 4 phosphorylation leads to pathological cardiac remodeling in mice.
Li L, Zhang Q, Zhang X, Zhang J, Wang X, Ren J, Jia J, Zhang D, Jiang X, Zhang J, Mei H, Chen B, Hu J, Huang Y
EBioMedicine 2018 Nov;37:221-235
EBioMedicine 2018 Nov;37:221-235
METTL3-mediated N(6)-methyladenosine mRNA modification enhances long-term memory consolidation.
Zhang Z, Wang M, Xie D, Huang Z, Zhang L, Yang Y, Ma D, Li W, Zhou Q, Yang YG, Wang XJ
Cell research 2018 Nov;28(11):1050-1061
Cell research 2018 Nov;28(11):1050-1061
miR-153 inhibits the migration and the tube formation of endothelial cells by blocking the paracrine of angiopoietin 1 in breast cancer cells.
Liang H, Ge F, Xu Y, Xiao J, Zhou Z, Liu R, Chen C
Angiogenesis 2018 Nov;21(4):849-860
Angiogenesis 2018 Nov;21(4):849-860
Silencing of rhomboid domain containing 1 to inhibit the metastasis of human breast cancer cells in vitro.
Huang C, Ji X, Peng Y, Wu M, Wu W, Luo Y, Cheng G, Zhu Y
Iranian journal of basic medical sciences 2018 Nov;21(11):1161-1166
Iranian journal of basic medical sciences 2018 Nov;21(11):1161-1166
Deficiency in augmenter of liver regeneration accelerates liver fibrosis by promoting migration of hepatic stellate cell.
Ai WL, Dong LY, Wang J, Li ZW, Wang X, Gao J, Wu Y, An W
Biochimica et biophysica acta. Molecular basis of disease 2018 Nov;1864(11):3780-3791
Biochimica et biophysica acta. Molecular basis of disease 2018 Nov;1864(11):3780-3791
Boron Affects the Development of the Kidney Through Modulation of Apoptosis, Antioxidant Capacity, and Nrf2 Pathway in the African Ostrich Chicks.
Khaliq H, Jing W, Ke X, Ke-Li Y, Peng-Peng S, Cui L, Wei-Wei Q, Zhixin L, Hua-Zhen L, Hui S, Ju-Ming Z, Ke-Mei P
Biological trace element research 2018 Nov;186(1):226-237
Biological trace element research 2018 Nov;186(1):226-237
Cantharidin inhibits melanoma cell proliferation via the miR‑21‑mediated PTEN pathway.
Mu Z, Sun Q
Molecular medicine reports 2018 Nov;18(5):4603-4610
Molecular medicine reports 2018 Nov;18(5):4603-4610
Protective effects of α‑2‑macroglobulin on human bone marrow mesenchymal stem cells in radiation injury.
Liu Y, Cao W, Kong X, Li J, Chen X, Ge Y, Zhong W, Fang S
Molecular medicine reports 2018 Nov;18(5):4219-4228
Molecular medicine reports 2018 Nov;18(5):4219-4228
Hepatitis B virus X protein promotes epithelial-mesenchymal transition and metastasis in hepatocellular carcinoma cell line HCCLM3 by targeting HMGA2.
Zha Y, Yao Q, Liu JS, Wang YY, Sun WM
Oncology letters 2018 Nov;16(5):5709-5714
Oncology letters 2018 Nov;16(5):5709-5714
METTL3 promotes ovarian carcinoma growth and invasion through the regulation of AXL translation and epithelial to mesenchymal transition.
Hua W, Zhao Y, Jin X, Yu D, He J, Xie D, Duan P
Gynecologic oncology 2018 Nov;151(2):356-365
Gynecologic oncology 2018 Nov;151(2):356-365
Blocking LINC00152 suppresses glioblastoma malignancy by impairing mesenchymal phenotype through the miR-612/AKT2/NF-κB pathway.
Cai J, Zhang J, Wu P, Yang W, Ye Q, Chen Q, Jiang C
Journal of neuro-oncology 2018 Nov;140(2):225-236
Journal of neuro-oncology 2018 Nov;140(2):225-236
Activation of α7 nicotinic acetylcholine receptor alleviates Aβ(1-42)-induced neurotoxicity via downregulation of p38 and JNK MAPK signaling pathways.
Chang KW, Zong HF, Ma KG, Zhai WY, Yang WN, Hu XD, Xu JH, Chen XL, Ji SF, Qian YH
Neurochemistry international 2018 Nov;120:238-250
Neurochemistry international 2018 Nov;120:238-250
Pathological cyclic strain promotes proliferation of vascular smooth muscle cells via the ACTH/ERK/STAT3 pathway.
Tang X, Liu Y, Xiao Q, Yao Q, Allen M, Wang Y, Gao L, Qi Y, Zhang P
Journal of cellular biochemistry 2018 Nov;119(10):8260-8270
Journal of cellular biochemistry 2018 Nov;119(10):8260-8270
Toll-like receptor 4 shRNA attenuates lipopolysaccharide-induced epithelial-mesenchymal transition of intrahepatic biliary epithelial cells in rats.
Tang S, Jiang X, Wu L, Chen S, Chen L, Jiang J, Yan P, Wang F, Tu K, Wang D, Gu J, Zhao L
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Nov;107:1210-1217
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Nov;107:1210-1217
miR-146b promotes cell proliferation and increases chemosensitivity, but attenuates cell migration and invasion via FBXL10 in ovarian cancer.
Yan M, Yang X, Shen R, Wu C, Wang H, Ye Q, Yang P, Zhang L, Chen M, Wan B, Zhang Q, Xia S, Lu X, Shao G, Zhou X, Yu J, Shao Q
Cell death & disease 2018 Nov 8;9(11):1123
Cell death & disease 2018 Nov 8;9(11):1123
Evaluation of a Potential Clinical Significant Drug-Drug Interaction between Digoxin and Bupropion in Cynomolgus Monkeys.
Shen Y, Yu Y, Lai W, Li S, Xu Z, Jin J, Yan X, Xing H, Chen X, Xiong A, Xia C, He J, Hong K
Pharmaceutical research 2018 Nov 6;36(1):1
Pharmaceutical research 2018 Nov 6;36(1):1
Breed Differences in Pig Liver Esterase (PLE) between Tongcheng (Chinese Local Breed) and Large White Pigs.
Xiao Q, Zhou Q, Yang L, Tian Z, Wang X, Xiao Y, Shi D
Scientific reports 2018 Nov 5;8(1):16364
Scientific reports 2018 Nov 5;8(1):16364
Synergetic and Antagonistic Molecular Effects Mediated by the Feedback Loop of p53 and JNK between Saikosaponin D and SP600125 on Lung Cancer A549 Cells.
Chen X, Liu C, Zhao R, Zhao P, Wu J, Zhou N, Ying M
Molecular pharmaceutics 2018 Nov 5;15(11):4974-4984
Molecular pharmaceutics 2018 Nov 5;15(11):4974-4984
Vasculogenic mimicry formation in EBV-associated epithelial malignancies.
Xiang T, Lin YX, Ma W, Zhang HJ, Chen KM, He GP, Zhang X, Xu M, Feng QS, Chen MY, Zeng MS, Zeng YX, Feng L
Nature communications 2018 Nov 27;9(1):5009
Nature communications 2018 Nov 27;9(1):5009
Abnormally elevated USP37 expression in breast cancer stem cells regulates stemness, epithelial-mesenchymal transition and cisplatin sensitivity.
Qin T, Li B, Feng X, Fan S, Liu L, Liu D, Mao J, Lu Y, Yang J, Yu X, Zhang Q, Zhang J, Song B, Li M, Li L
Journal of experimental & clinical cancer research : CR 2018 Nov 27;37(1):287
Journal of experimental & clinical cancer research : CR 2018 Nov 27;37(1):287
The Mitochondrial Apoptotic Effectors BAX/BAK Activate Caspase-3 and -7 to Trigger NLRP3 Inflammasome and Caspase-8 Driven IL-1β Activation.
Vince JE, De Nardo D, Gao W, Vince AJ, Hall C, McArthur K, Simpson D, Vijayaraj S, Lindqvist LM, Bouillet P, Rizzacasa MA, Man SM, Silke J, Masters SL, Lessene G, Huang DCS, Gray DHD, Kile BT, Shao F, Lawlor KE
Cell reports 2018 Nov 27;25(9):2339-2353.e4
Cell reports 2018 Nov 27;25(9):2339-2353.e4
Aspergillus fumigatus phospholipase D may enhance reactive oxygen species production by accumulation of histone deacetylase 6.
Yu S, Huo K
Biochemical and biophysical research communications 2018 Nov 2;505(3):651-656
Biochemical and biophysical research communications 2018 Nov 2;505(3):651-656
Tetrachlorobenzoquinone-Induced Nrf2 Confers Neuron-like PC12 Cells Resistance to Endoplasmic Reticulum Stress via Regulating Glutathione Synthesis and Protein Thiol Homeostasis.
Liu Z, Dong W, Yang B, Peng L, Xia X, Pu L, Zhang N, Song E, Song Y
Chemical research in toxicology 2018 Nov 19;31(11):1230-1239
Chemical research in toxicology 2018 Nov 19;31(11):1230-1239
PJA1 Coordinates with the SMC5/6 Complex To Restrict DNA Viruses and Episomal Genes in an Interferon-Independent Manner.
Xu W, Ma C, Zhang Q, Zhao R, Hu D, Zhang X, Chen J, Liu F, Wu K, Liu Y, Wu J
Journal of virology 2018 Nov 15;92(22)
Journal of virology 2018 Nov 15;92(22)
Up-regulation of LncRNA MEG3 inhibits cell migration and invasion and enhances cisplatin chemosensitivity in bladder cancer cells.
Feng SQ, Zhang XY, Fan HT, Sun QJ, Zhang M
Neoplasma 2018 Nov 15;65(6):925-932
Neoplasma 2018 Nov 15;65(6):925-932
CHCHD2 accumulates in distressed mitochondria and facilitates oligomerization of CHCHD10.
Huang X, Wu BP, Nguyen D, Liu YT, Marani M, Hench J, Bénit P, Kozjak-Pavlovic V, Rustin P, Frank S, Narendra DP
Human molecular genetics 2018 Nov 15;27(22):3881-3900
Human molecular genetics 2018 Nov 15;27(22):3881-3900
Hemopexin reduces blood-brain barrier injury and protects synaptic plasticity in cerebral ischemic rats by promoting EPCs through the HO-1 pathway.
Yang Y, Dong B, Lu J, Wang G, Yu Y
Brain research 2018 Nov 15;1699:177-185
Brain research 2018 Nov 15;1699:177-185
Tannic acid directly targets pyruvate kinase isoenzyme M2 to attenuate colon cancer cell proliferation.
Yang P, Ding GB, Liu W, Fu R, Sajid A, Li Z
Food & function 2018 Nov 14;9(11):5547-5559
Food & function 2018 Nov 14;9(11):5547-5559
Upregulation of circ-UBAP2 predicts poor prognosis and promotes triple-negative breast cancer progression through the miR-661/MTA1 pathway.
Wang S, Li Q, Wang Y, Li X, Wang R, Kang Y, Xue X, Meng R, Wei Q, Feng X
Biochemical and biophysical research communications 2018 Nov 10;505(4):996-1002
Biochemical and biophysical research communications 2018 Nov 10;505(4):996-1002
Astragaloside exerts anti-photoaging effects in UVB-induced premature senescence of rat dermal fibroblasts through enhanced autophagy.
Wen W, Chen J, Ding L, Luo X, Zheng X, Dai Q, Gu Q, Liu C, Liang M, Guo X, Liu P, Li M
Archives of biochemistry and biophysics 2018 Nov 1;657:31-40
Archives of biochemistry and biophysics 2018 Nov 1;657:31-40
Expression of programmed cell death protein 1 (PD-1) and indoleamine 2,3-dioxygenase (IDO) in the tumor microenvironment and in tumor-draining lymph nodes of breast cancer.
Ye Q, Wang C, Xian J, Zhang M, Cao Y, Cao Y
Human pathology 2018 May;75:81-90
Human pathology 2018 May;75:81-90
Progranulin promotes lymphangiogenesis through VEGF-C and is an independent risk factor in human esophageal cancers.
Li G, Dong T, Yang D, Gao A, Luo J, Yang H, Wang L
Human pathology 2018 May;75:116-124
Human pathology 2018 May;75:116-124
MicroRNA-181c promotes Th17 cell differentiation and mediates experimental autoimmune encephalomyelitis.
Zhang Z, Xue Z, Liu Y, Liu H, Guo X, Li Y, Yang H, Zhang L, Da Y, Yao Z, Zhang R
Brain, behavior, and immunity 2018 May;70:305-314
Brain, behavior, and immunity 2018 May;70:305-314
Resveratrol Improves Muscle Atrophy by Modulating Mitochondrial Quality Control in STZ-Induced Diabetic Mice.
Wang D, Sun H, Song G, Yang Y, Zou X, Han P, Li S
Molecular nutrition & food research 2018 May;62(9):e1700941
Molecular nutrition & food research 2018 May;62(9):e1700941
Follicle-stimulating hormone enhances hepatic gluconeogenesis by GRK2-mediated AMPK hyperphosphorylation at Ser485 in mice.
Qi X, Guo Y, Song Y, Yu C, Zhao L, Fang L, Kong D, Zhao J, Gao L
Diabetologia 2018 May;61(5):1180-1192
Diabetologia 2018 May;61(5):1180-1192
CEACAM1 resists hypoxia-induced inhibition of tube formation of human dermal lymphatic endothelial cells.
Xie Q, Chen X, Xu Y, Liang J, Wang F, Liu J
Cellular signalling 2018 May;45:145-152
Cellular signalling 2018 May;45:145-152
Ultrasound Irradiation Combined with Hepatocyte Growth Factor Accelerate the Hepatic Differentiation of Human Bone Marrow Mesenchymal Stem Cells.
Li F, Liu Y, Cai Y, Li X, Bai M, Sun T, Du L
Ultrasound in medicine & biology 2018 May;44(5):1044-1052
Ultrasound in medicine & biology 2018 May;44(5):1044-1052
Effect of placental sex hormone-binding globulin single nucleotide polymorphism rs6259 on protein and function in gestational diabetes mellitus.
Zhang X, Sun L, Jin Z
International journal of molecular medicine 2018 May;41(5):2927-2934
International journal of molecular medicine 2018 May;41(5):2927-2934
Identification of Functional Thyroid Stimulating Hormone Receptor and TSHR Gene Mutations in Hepatocellular Carcinoma.
Shih YL, Huang YH, Lin KH, Chu YD, Yeh CT
Anticancer research 2018 May;38(5):2793-2802
Anticancer research 2018 May;38(5):2793-2802
The E3 ubiquitin ligase Triad1 influences development of Mll-Ell-induced acute myeloid leukemia.
Wang H, Bei L, Shah CA, Huang W, Platanias LC, Eklund EA
Oncogene 2018 May;37(19):2532-2544
Oncogene 2018 May;37(19):2532-2544
LncRNA-PVT1 promotes pancreatic cancer cells proliferation and migration through acting as a molecular sponge to regulate miR-448.
Zhao L, Kong H, Sun H, Chen Z, Chen B, Zhou M
Journal of cellular physiology 2018 May;233(5):4044-4055
Journal of cellular physiology 2018 May;233(5):4044-4055
Antagonism of cortistatin against cyclosporine-induced apoptosis in rat myocardial cells and its effect on myocardial apoptosis gene expression.
Geng L, Wang XT, Yu J, Yang YL
European review for medical and pharmacological sciences 2018 May;22(10):3207-3213
European review for medical and pharmacological sciences 2018 May;22(10):3207-3213
PVT1 regulates the malignant behaviors of human glioma cells by targeting miR-190a-5p and miR-488-3p.
Xue W, Chen J, Liu X, Gong W, Zheng J, Guo X, Liu Y, Liu L, Ma J, Wang P, Li Z, Xue Y
Biochimica et biophysica acta. Molecular basis of disease 2018 May;1864(5 Pt A):1783-1794
Biochimica et biophysica acta. Molecular basis of disease 2018 May;1864(5 Pt A):1783-1794
FTO promotes SREBP1c maturation and enhances CIDEC transcription during lipid accumulation in HepG2 cells.
Chen A, Chen X, Cheng S, Shu L, Yan M, Yao L, Wang B, Huang S, Zhou L, Yang Z, Liu G
Biochimica et biophysica acta. Molecular and cell biology of lipids 2018 May;1863(5):538-548
Biochimica et biophysica acta. Molecular and cell biology of lipids 2018 May;1863(5):538-548
Targeting Polo-like Kinase 1 by a Novel Pyrrole-Imidazole Polyamide-Hoechst Conjugate Suppresses Tumor Growth In Vivo.
Liu K, Fang L, Sun H, Pan Z, Zhang J, Chen J, Shao X, Wang W, Tan Y, Ding Z, Ao L, Wu C, Liu X, Li H, Wang R, Su W, Li H
Molecular cancer therapeutics 2018 May;17(5):988-1002
Molecular cancer therapeutics 2018 May;17(5):988-1002
Liraglutide improves hepatic insulin resistance via the canonical Wnt signaling pathway.
Qin Y, Chen M, Yang Y, Zhou XR, Shao SY, Wang DW, Yuan G
Molecular medicine reports 2018 May;17(5):7372-7380
Molecular medicine reports 2018 May;17(5):7372-7380
Local intra‑articular injection of vascular endothelial growth factor accelerates articular cartilage degeneration in rat osteoarthritis model.
Deng S, Zhou JL, Peng H, Fang HS, Liu F, Weng JQ
Molecular medicine reports 2018 May;17(5):6311-6318
Molecular medicine reports 2018 May;17(5):6311-6318
Cantharidin suppresses cell growth and migration, and activates autophagy in human non-small cell lung cancer cells.
Liu YP, Li L, Xu L, Dai EN, Chen WD
Oncology letters 2018 May;15(5):6527-6532
Oncology letters 2018 May;15(5):6527-6532
M2-specific reduction of CD1d switches NKT cell-mediated immune responses and triggers metaflammation in adipose tissue.
Zhang H, Xue R, Zhu S, Fu S, Chen Z, Zhou R, Tian Z, Bai L
Cellular & molecular immunology 2018 May;15(5):506-517
Cellular & molecular immunology 2018 May;15(5):506-517
Cardioprotection of CAPE-oNO(2) against myocardial ischemia/reperfusion induced ROS generation via regulating the SIRT1/eNOS/NF-κB pathway in vivo and in vitro.
Li D, Wang X, Huang Q, Li S, Zhou Y, Li Z
Redox biology 2018 May;15:62-73
Redox biology 2018 May;15:62-73
The glucagon-like peptide-1 (GLP-1) analog liraglutide attenuates renal fibrosis.
Li YK, Ma DX, Wang ZM, Hu XF, Li SL, Tian HZ, Wang MJ, Shu YW, Yang J
Pharmacological research 2018 May;131:102-111
Pharmacological research 2018 May;131:102-111
Diallyl Trisulfide inhibits breast cancer stem cells via suppression of Wnt/β-catenin pathway.
Li X, Meng Y, Xie C, Zhu J, Wang X, Li Y, Geng S, Wu J, Zhong C, Li M
Journal of cellular biochemistry 2018 May;119(5):4134-4141
Journal of cellular biochemistry 2018 May;119(5):4134-4141
Activation of AMPK by simvastatin inhibited breast tumor angiogenesis via impeding HIF-1α-induced pro-angiogenic factor.
Wang JC, Li XX, Sun X, Li GY, Sun JL, Ye YP, Cong LL, Li WM, Lu SY, Feng J, Liu PJ
Cancer science 2018 May;109(5):1627-1637
Cancer science 2018 May;109(5):1627-1637
Perfluorooctane sulfonate mediates secretion of IL-1β through PI3K/AKT NF-кB pathway in astrocytes.
Chen X, Nie X, Mao J, Zhang Y, Yin K, Sun P, Luo J, Liu Y, Jiang S, Sun L
Neurotoxicology and teratology 2018 May-Jun;67:65-75
Neurotoxicology and teratology 2018 May-Jun;67:65-75
Chromosome Segregation Is Biased by Kinetochore Size.
Drpic D, Almeida AC, Aguiar P, Renda F, Damas J, Lewin HA, Larkin DM, Khodjakov A, Maiato H
Current biology : CB 2018 May 7;28(9):1344-1356.e5
Current biology : CB 2018 May 7;28(9):1344-1356.e5
CysLTR1 Blockage Ameliorates Liver Injury Caused by Aluminum-Overload via PI3K/AKT/mTOR-Mediated Autophagy Activation in Vivo and in Vitro.
Hu C, Yang J, He Q, Luo Y, Chen Z, Yang L, Yi H, Li H, Xia H, Ran D, Yang Y, Zhang J, Li Y, Wang H
Molecular pharmaceutics 2018 May 7;15(5):1996-2006
Molecular pharmaceutics 2018 May 7;15(5):1996-2006
Interleukin-23 promotes the migration and invasion of gastric cancer cells by inducing epithelial-to-mesenchymal transition via the STAT3 pathway.
Xu X, Yang C, Chen J, Liu J, Li P, Shi Y, Yu P
Biochemical and biophysical research communications 2018 May 5;499(2):273-278
Biochemical and biophysical research communications 2018 May 5;499(2):273-278
Dysregulation of tristetraprolin and human antigen R promotes gastric cancer progressions partly by upregulation of the high-mobility group box 1.
Wang H, Chen Y, Guo J, Shan T, Deng K, Chen J, Cai L, Zhou H, Zhao Q, Jin S, Xia J
Scientific reports 2018 May 4;8(1):7080
Scientific reports 2018 May 4;8(1):7080
The Novel miRNA N-72 Regulates EGF-Induced Migration of Human Amnion Mesenchymal Stem Cells by Targeting MMP2.
Li Y, Zhang D, Chen M, Wang R, Zhang T, Zhao F, Lin X, Pang X
International journal of molecular sciences 2018 May 4;19(5)
International journal of molecular sciences 2018 May 4;19(5)
Resting T cells are hypersensitive to DNA damage due to defective DNA repair pathway.
Hu Q, Xie Y, Ge Y, Nie X, Tao J, Zhao Y
Cell death & disease 2018 May 31;9(6):662
Cell death & disease 2018 May 31;9(6):662
Dietary supplementation with ketoacids protects against CKD-induced oxidative damage and mitochondrial dysfunction in skeletal muscle of 5/6 nephrectomised rats.
Wang D, Wei L, Yang Y, Liu H
Skeletal muscle 2018 May 31;8(1):18
Skeletal muscle 2018 May 31;8(1):18
Identification of Selective, Cell Active Inhibitors of Protein Arginine Methyltransferase 5 through Structure-Based Virtual Screening and Biological Assays.
Ye F, Zhang W, Ye X, Jin J, Lv Z, Luo C
Journal of chemical information and modeling 2018 May 29;58(5):1066-1073
Journal of chemical information and modeling 2018 May 29;58(5):1066-1073
MiR-29c reduces the cisplatin resistance of non-small cell lung cancer cells by negatively regulating the PI3K/Akt pathway.
Sun DM, Tang BF, Li ZX, Guo HB, Cheng JL, Song PP, Zhao X
Scientific reports 2018 May 22;8(1):8007
Scientific reports 2018 May 22;8(1):8007
[Role of allograft inflammatory factor-1 in regulating the proliferation, migration and apoptosis of colorectal cancer cells].
Ai XL, Yao F, Wang XJ, Duan DB, Li K, Hu ZY, Yin G, Wang M, Wu BY
Nan fang yi ke da xue xue bao = Journal of Southern Medical University 2018 May 20;38(5):511-519
Nan fang yi ke da xue xue bao = Journal of Southern Medical University 2018 May 20;38(5):511-519
Dexmedetomidine reduces ventilator-induced lung injury (VILI) by inhibiting Toll-like receptor 4 (TLR4)/nuclear factor (NF)-κB signaling pathway.
Chen H, Sun X, Yang X, Hou Y, Yu X, Wang Y, Wu J, Liu D, Wang H, Yu J, Yi W
Bosnian journal of basic medical sciences 2018 May 20;18(2):162-169
Bosnian journal of basic medical sciences 2018 May 20;18(2):162-169
Apolipoprotein C1 promotes prostate cancer cell proliferation in vitro.
Su WP, Sun LN, Yang SL, Zhao H, Zeng TY, Wu WZ, Wang D
Journal of biochemical and molecular toxicology 2018 May 2;32(7):e22158
Journal of biochemical and molecular toxicology 2018 May 2;32(7):e22158
Long-term exposure to low-dose Haemophilus influenzae during allergic airway disease drives a steroid-resistant neutrophilic inflammation and promotes airway remodeling.
Yang X, Wang Y, Zhao S, Wang R, Wang C
Oncotarget 2018 May 18;9(38):24898-24913
Oncotarget 2018 May 18;9(38):24898-24913
Rotenone ameliorates chronic renal injury caused by acute ischemia/reperfusion.
Zhang W, Sha Y, Wei K, Wu C, Ding D, Yang Y, Zhu C, Zhang Y, Ding G, Zhang A, Jia Z, Huang S
Oncotarget 2018 May 11;9(36):24199-24208
Oncotarget 2018 May 11;9(36):24199-24208
Single-Cell Analysis of the Impact of Host Cell Heterogeneity on Infection with Foot-and-Mouth Disease Virus.
Xin X, Wang H, Han L, Wang M, Fang H, Hao Y, Li J, Zhang H, Zheng C, Shen C
Journal of virology 2018 May 1;92(9)
Journal of virology 2018 May 1;92(9)
Autophagic degradation of caveolin-1 promotes liver sinusoidal endothelial cells defenestration.
Luo X, Wang D, Zhu X, Wang G, You Y, Ning Z, Li Y, Jin S, Huang Y, Hu Y, Chen T, Meng Y, Li X
Cell death & disease 2018 May 1;9(5):576
Cell death & disease 2018 May 1;9(5):576
KIF4A facilitates cell proliferation via induction of p21-mediated cell cycle progression and promotes metastasis in colorectal cancer.
Hou PF, Jiang T, Chen F, Shi PC, Li HQ, Bai J, Song J
Cell death & disease 2018 May 1;9(5):477
Cell death & disease 2018 May 1;9(5):477
Dkk3 dependent transcriptional regulation controls age related skeletal muscle atrophy.
Yin J, Yang L, Xie Y, Liu Y, Li S, Yang W, Xu B, Ji H, Ding L, Wang K, Li G, Chen L, Hu P
Nature communications 2018 May 1;9(1):1752
Nature communications 2018 May 1;9(1):1752
Inhibition of transient receptor potential melastatin 8 alleviates airway inflammation and remodeling in a murine model of asthma with cold air stimulus.
Liu H, Liu Q, Hua L, Pan J
Acta biochimica et biophysica Sinica 2018 May 1;50(5):499-506
Acta biochimica et biophysica Sinica 2018 May 1;50(5):499-506
Rewiring of Glutamine Metabolism Is a Bioenergetic Adaptation of Human Cells with Mitochondrial DNA Mutations.
Chen Q, Kirk K, Shurubor YI, Zhao D, Arreguin AJ, Shahi I, Valsecchi F, Primiano G, Calder EL, Carelli V, Denton TT, Beal MF, Gross SS, Manfredi G, D'Aurelio M
Cell metabolism 2018 May 1;27(5):1007-1025.e5
Cell metabolism 2018 May 1;27(5):1007-1025.e5
The Dopamine Receptor D3 Regulates Lipopolysaccharide-Induced Depressive-Like Behavior in Mice.
Wang J, Jia Y, Li G, Wang B, Zhou T, Zhu L, Chen T, Chen Y
The international journal of neuropsychopharmacology 2018 May 1;21(5):448-460
The international journal of neuropsychopharmacology 2018 May 1;21(5):448-460
Glial fibrillary acidic protein promoter determines transgene expression in satellite glial cells following intraganglionic adeno-associated virus delivery in adult rats.
Xiang H, Xu H, Fan F, Shin SM, Hogan QH, Yu H
Journal of neuroscience research 2018 Mar;96(3):436-448
Journal of neuroscience research 2018 Mar;96(3):436-448
Periostin promotes migration, proliferation, and differentiation of human periodontal ligament mesenchymal stem cells.
Wu Z, Dai W, Wang P, Zhang X, Tang Y, Liu L, Wang Q, Li M, Tang C
Connective tissue research 2018 Mar;59(2):108-119
Connective tissue research 2018 Mar;59(2):108-119
Combination Treatment with Methylene Blue and Hypothermia in Global Cerebral Ischemia.
Li L, Yang R, Li P, Lu H, Hao J, Li L, Tucker D, Zhang Q
Molecular neurobiology 2018 Mar;55(3):2042-2055
Molecular neurobiology 2018 Mar;55(3):2042-2055
Role of the hippocampal 5-HT1A receptor-mediated cAMP/PKA signalling pathway in sevoflurane-induced cognitivedysfunction in aged rats.
Qiu Y, Wang Y, Wang X, Wang C, Xia ZY
The Journal of international medical research 2018 Mar;46(3):1073-1085
The Journal of international medical research 2018 Mar;46(3):1073-1085
Baicalin protects H9c2 cardiomyocytes against hypoxia/reoxygenation-induced apoptosis and oxidative stress through activation of mitochondrial aldehyde dehydrogenase 2.
Jiang WB, Zhao W, Chen H, Wu YY, Wang Y, Fu GS, Yang XJ
Clinical and experimental pharmacology & physiology 2018 Mar;45(3):303-311
Clinical and experimental pharmacology & physiology 2018 Mar;45(3):303-311
Analysis of the oncogene BRAF mutation and the correlation of the expression of wild-type BRAF and CREB1 in endometriosis.
Lv X, Wang D, Ma Y, Long Z
International journal of molecular medicine 2018 Mar;41(3):1349-1356
International journal of molecular medicine 2018 Mar;41(3):1349-1356
Tumor-suppressive miRNA-135a inhibits breast cancer cell proliferation by targeting ELK1 and ELK3 oncogenes.
Ahmad A, Zhang W, Wu M, Tan S, Zhu T
Genes & genomics 2018 Mar;40(3):243-251
Genes & genomics 2018 Mar;40(3):243-251
miR-141 inhibits prostatic cancer cell proliferation and migration, and induces cell apoptosis via targeting of RUNX1.
Xu S, Ge J, Zhang Z, Zhou W
Oncology reports 2018 Mar;39(3):1454-1460
Oncology reports 2018 Mar;39(3):1454-1460
TAp63 is correlated with chronic inflammation in patients with newly diagnosed type 2 diabetes mellitus.
Hu X, Liu J, Sun L, Liu L, Hu Y, Yuan Y, Wu G, Wang Y, Chen J, Xu Y
Journal of diabetes and its complications 2018 Mar;32(3):335-341
Journal of diabetes and its complications 2018 Mar;32(3):335-341
Identification of a novel compound targeting the nuclear export of influenza A virus nucleoprotein.
Huang F, Chen J, Zhang J, Tan L, Lu G, Luo Y, Pan T, Liang J, Li Q, Luo B, Zhang H, Lu G
Journal of cellular and molecular medicine 2018 Mar;22(3):1826-1839
Journal of cellular and molecular medicine 2018 Mar;22(3):1826-1839
Analysis of the association of the expression of KiSS-1 in colorectal cancer tissues with the pathology and prognosis.
Huo X, Zhang L, Li T
Oncology letters 2018 Mar;15(3):3056-3060
Oncology letters 2018 Mar;15(3):3056-3060
miR-98 inhibits cell proliferation and induces cell apoptosis by targeting MAPK6 in HUVECs.
Hu C, Huang S, Wu F, Ding H
Experimental and therapeutic medicine 2018 Mar;15(3):2755-2760
Experimental and therapeutic medicine 2018 Mar;15(3):2755-2760
Type I IFN augments IL-27-dependent TRIM25 expression to inhibit HBV replication.
Tan G, Xiao Q, Song H, Ma F, Xu F, Peng D, Li N, Wang X, Niu J, Gao P, Qin FX, Cheng G
Cellular & molecular immunology 2018 Mar;15(3):272-281
Cellular & molecular immunology 2018 Mar;15(3):272-281
MAD2L2 inhibits colorectal cancer growth by promoting NCOA3 ubiquitination and degradation.
Li Y, Li L, Chen M, Yu X, Gu Z, Qiu H, Qin G, Long Q, Fu X, Liu T, Li W, Huang W, Shi D, Kang T, Luo M, Wu X, Deng W
Molecular oncology 2018 Mar;12(3):391-405
Molecular oncology 2018 Mar;12(3):391-405
Protein kinase C epsilon mediates the inhibition of angiotensin II on the slowly activating delayed-rectifier potassium current through channel phosphorylation.
Gou X, Wang W, Zou S, Qi Y, Xu Y
Journal of molecular and cellular cardiology 2018 Mar;116:165-174
Journal of molecular and cellular cardiology 2018 Mar;116:165-174
Lanthanum chloride impairs memory in rats by disturbing the glutamate-glutamine cycle and over-activating NMDA receptors.
Hu X, Yang J, Sun Y, Gao X, Zhang L, Li Y, Yu M, Liu S, Lu X, Jin C, Wu S, Cai Y
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2018 Mar;113:1-13
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2018 Mar;113:1-13
The expression of the new epididymal luminal protein of PDZ domain containing 1 is decreased in asthenozoospermia.
Liang AJ, Wang GS, Ping P, Hu SG, Lin Y, Ma Y, Duan ZZ, Wang HS, Sun F
Asian journal of andrology 2018 Mar-Apr;20(2):154-159
Asian journal of andrology 2018 Mar-Apr;20(2):154-159
MiR-134, epigenetically silenced in gliomas, could mitigate the malignant phenotype by targeting KRAS.
Wang ZL, Zhang CB, Wang Z, Meng XQ, Liu XJ, Han B, Duan CB, Cai JQ, Hao ZF, Chen MH, Jiang T, Li YL, Jiang CL, Wang HJ
Carcinogenesis 2018 Mar 8;39(3):389-396
Carcinogenesis 2018 Mar 8;39(3):389-396
SFTS phlebovirus promotes LC3-II accumulation and nonstructural protein of SFTS phlebovirus co-localizes with autophagy proteins.
Sun Y, Liu MM, Lei XY, Yu XJ
Scientific reports 2018 Mar 27;8(1):5287
Scientific reports 2018 Mar 27;8(1):5287
Inhibition of HIV early replication by the p53 and its downstream gene p21.
Shi B, Sharifi HJ, DiGrigoli S, Kinnetz M, Mellon K, Hu W, de Noronha CMC
Virology journal 2018 Mar 27;15(1):53
Virology journal 2018 Mar 27;15(1):53
Overexpression of zinc-α2-glycoprotein suppressed seizures and seizure-related neuroflammation in pentylenetetrazol-kindled rats.
Liu Y, Wang T, Liu X, Wen Y, Xu T, Yu X, Wei X, Ding X, Mo L, Yin M, Tan X, Chen L
Journal of neuroinflammation 2018 Mar 22;15(1):92
Journal of neuroinflammation 2018 Mar 22;15(1):92
The transcriptional profiles and functional implications of long non-coding RNAs in the unfolded protein response.
Quan H, Fan Q, Li C, Wang YY, Wang L
Scientific reports 2018 Mar 21;8(1):4981
Scientific reports 2018 Mar 21;8(1):4981
Regulation by FSH of the dynamic expression of retinol-binding protein 4 in the mouse ovary.
Jiang Y, Zhao Y, Chen S, Chen L, Li C, Zhou X
Reproductive biology and endocrinology : RB&E 2018 Mar 20;16(1):25
Reproductive biology and endocrinology : RB&E 2018 Mar 20;16(1):25
Transmembrane E3 ligase RNF183 mediates ER stress-induced apoptosis by degrading Bcl-xL.
Wu Y, Li X, Jia J, Zhang Y, Li J, Zhu Z, Wang H, Tang J, Hu J
Proceedings of the National Academy of Sciences of the United States of America 2018 Mar 20;115(12):E2762-E2771
Proceedings of the National Academy of Sciences of the United States of America 2018 Mar 20;115(12):E2762-E2771
Pin1 mediates Aβ(42)-induced dendritic spine loss.
Stallings NR, O'Neal MA, Hu J, Kavalali ET, Bezprozvanny I, Malter JS
Science signaling 2018 Mar 20;11(522)
Science signaling 2018 Mar 20;11(522)
PIWIL1/piRNA-DQ593109 Regulates the Permeability of the Blood-Tumor Barrier via the MEG3/miR-330-5p/RUNX3 Axis.
Shen S, Yu H, Liu X, Liu Y, Zheng J, Wang P, Gong W, Chen J, Zhao L, Xue Y
Molecular therapy. Nucleic acids 2018 Mar 2;10:412-425
Molecular therapy. Nucleic acids 2018 Mar 2;10:412-425
circ-SHKBP1 Regulates the Angiogenesis of U87 Glioma-Exposed Endothelial Cells through miR-544a/FOXP1 and miR-379/FOXP2 Pathways.
He Q, Zhao L, Liu Y, Liu X, Zheng J, Yu H, Cai H, Ma J, Liu L, Wang P, Li Z, Xue Y
Molecular therapy. Nucleic acids 2018 Mar 2;10:331-348
Molecular therapy. Nucleic acids 2018 Mar 2;10:331-348
Zc3h13 Regulates Nuclear RNA m(6)A Methylation and Mouse Embryonic Stem Cell Self-Renewal.
Wen J, Lv R, Ma H, Shen H, He C, Wang J, Jiao F, Liu H, Yang P, Tan L, Lan F, Shi YG, He C, Shi Y, Diao J
Molecular cell 2018 Mar 15;69(6):1028-1038.e6
Molecular cell 2018 Mar 15;69(6):1028-1038.e6
In vitro study of FUZ as a novel potential therapeutic target in non-small-cell lung cancer.
He M, Li K, Yu C, Lv B, Zhao N, Deng J, Cao L, Huang H, Yin A, Shi T, Wang L
Life sciences 2018 Mar 15;197:91-100
Life sciences 2018 Mar 15;197:91-100
Cigarette smoke stimulates the stemness of renal cancer stem cells via Sonic Hedgehog pathway.
Qian W, Kong X, Zhang T, Wang D, Song J, Li Y, Li X, Geng H, Min J, Kong Q, Liu J, Liu Z, Wang D, Zhang Z, Yu D, Zhong C
Oncogenesis 2018 Mar 13;7(3):24
Oncogenesis 2018 Mar 13;7(3):24
Structural Basis for the Inhibition of Host Gene Expression by Porcine Epidemic Diarrhea Virus nsp1.
Shen Z, Ye G, Deng F, Wang G, Cui M, Fang L, Xiao S, Fu ZF, Peng G
Journal of virology 2018 Mar 1;92(5)
Journal of virology 2018 Mar 1;92(5)
LncRNA UCA1 attenuates autophagy-dependent cell death through blocking autophagic flux under arsenic stress.
Gao M, Li C, Xu M, Liu Y, Liu S
Toxicology letters 2018 Mar 1;284:195-204
Toxicology letters 2018 Mar 1;284:195-204
Cell division cycle 7 is a potential therapeutic target in oral squamous cell carcinoma and is regulated by E2F1.
Jin S, Ma H, Yang W, Ju H, Wang L, Zhang Z
Journal of molecular medicine (Berlin, Germany) 2018 Jun;96(6):513-525
Journal of molecular medicine (Berlin, Germany) 2018 Jun;96(6):513-525
Propranolol prevents liver cirrhosis by inhibiting hepatic stellate cell activation mediated by the PDGFR/Akt pathway.
Ding Q, Li Z, Liu B, Ling L, Tian X, Zhang C
Human pathology 2018 Jun;76:37-46
Human pathology 2018 Jun;76:37-46
Setd7 and its contribution to Boron-induced bone regeneration in Boron-mesoporous bioactive glass scaffolds.
Yin C, Jia X, Miron RJ, Long Q, Xu H, Wei Y, Wu M, Zhang Y, Li Z
Acta biomaterialia 2018 Jun;73:522-530
Acta biomaterialia 2018 Jun;73:522-530
Clinical significance of combined detection of interleukin-6 and tumour markers in lung cancer.
Tang H, Bai Y, Shen W, Wei Y, Xu M, Zhou X, Zhao J
Autoimmunity 2018 Jun;51(4):191-198
Autoimmunity 2018 Jun;51(4):191-198
Oestrogen receptor β5 and epidermal growth factor receptor synergistically promote lung cancer progression.
Bai Y, Shen W, Zhang L, Yang Z, Xiong L, Tang H, Zhao J
Autoimmunity 2018 Jun;51(4):157-165
Autoimmunity 2018 Jun;51(4):157-165
Mutant KRAS promotes liver metastasis of colorectal cancer, in part, by upregulating the MEK-Sp1-DNMT1-miR-137-YB-1-IGF-IR signaling pathway.
Chu PC, Lin PC, Wu HY, Lin KT, Wu C, Bekaii-Saab T, Lin YJ, Lee CT, Lee JC, Chen CS
Oncogene 2018 Jun;37(25):3440-3455
Oncogene 2018 Jun;37(25):3440-3455
Sequestosome 1 protects esophageal squamous carcinoma cells from apoptosis via stabilizing SKP2 under serum starvation condition.
Shi C, Pan BQ, Shi F, Xie ZH, Jiang YY, Shang L, Zhang Y, Xu X, Cai Y, Hao JJ, Wang MR
Oncogene 2018 Jun;37(24):3260-3274
Oncogene 2018 Jun;37(24):3260-3274
Abberent expression of NOR1 protein in tumor associated macrophages contributes to the development of DEN-induced hepatocellular carcinoma.
Chen S, Zheng P, Wang W, Yi M, Chen P, Cai J, Li J, Peng Q, Ban Y, Zhou Y, Zeng Z, Li X, Xiong W, Li G, Xiang B
Journal of cellular physiology 2018 Jun;233(6):5002-5013
Journal of cellular physiology 2018 Jun;233(6):5002-5013
S1PR3 is essential for phosphorylated fingolimod to protect astrocytes against oxygen-glucose deprivation-induced neuroinflammation via inhibiting TLR2/4-NFκB signalling.
Dong YF, Guo RB, Ji J, Cao LL, Zhang L, Chen ZZ, Huang JY, Wu J, Lu J, Sun XL
Journal of cellular and molecular medicine 2018 Jun;22(6):3159-3166
Journal of cellular and molecular medicine 2018 Jun;22(6):3159-3166
Correlation between autophagy levels in peripheral blood mononuclear cells and clinical parameters in patients with chronic obstructive pulmonary disease.
Wu Y, Xu B, He X, Wu B, Li Y, Yu G, Tan C, Wang H
Molecular medicine reports 2018 Jun;17(6):8003-8009
Molecular medicine reports 2018 Jun;17(6):8003-8009
Osteogenesis potential of different titania nanotubes in oxidative stress microenvironment.
Yu Y, Shen X, Luo Z, Hu Y, Li M, Ma P, Ran Q, Dai L, He Y, Cai K
Biomaterials 2018 Jun;167:44-57
Biomaterials 2018 Jun;167:44-57
Protective effect of dioscin against doxorubicin-induced cardiotoxicity via adjusting microRNA-140-5p-mediated myocardial oxidative stress.
Zhao L, Tao X, Qi Y, Xu L, Yin L, Peng J
Redox biology 2018 Jun;16:189-198
Redox biology 2018 Jun;16:189-198
Downregulation of FOXP2 promotes breast cancer migration and invasion through TGFβ/SMAD signaling pathway.
Chen MT, Sun HF, Li LD, Zhao Y, Yang LP, Gao SP, Jin W
Oncology letters 2018 Jun;15(6):8582-8588
Oncology letters 2018 Jun;15(6):8582-8588
Excessive endoplasmic reticulum stress and decreased neuroplasticity-associated proteins in prefrontal cortex of obese rats and the regulatory effects of aerobic exercise.
Li F, Liu BB, Cai M, Li JJ, Lou SJ
Brain research bulletin 2018 Jun;140:52-59
Brain research bulletin 2018 Jun;140:52-59
Cognitive-enhancing effect of polysaccharides from Flammulina velutipes on Alzheimer's disease by compatibilizing with ginsenosides.
Zhang Y, Li H, Yang X, Jin G, Zhang Y
International journal of biological macromolecules 2018 Jun;112:788-795
International journal of biological macromolecules 2018 Jun;112:788-795
Krüppel-like factor 4 promotes c-Met amplification-mediated gefitinib resistance in non-small-cell lung cancer.
Feng W, Xie Q, Liu S, Ji Y, Li C, Wang C, Jin L
Cancer science 2018 Jun;109(6):1775-1786
Cancer science 2018 Jun;109(6):1775-1786
Effects of cholecalciferol cholesterol emulsion on renal fibrosis and aquaporin 2 and 4 in mice with unilateral ureteral obstruction.
Liu N, Zhang Y, Su H, Wang J, Liu Z, Kong J
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Jun;102:633-638
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Jun;102:633-638
Acetylation of oxidized base repair-initiating NEIL1 DNA glycosylase required for chromatin-bound repair complex formation in the human genome increases cellular resistance to oxidative stress.
Sengupta S, Yang C, Hegde ML, Hegde PM, Mitra J, Pandey A, Dutta A, Datarwala AT, Bhakat KK, Mitra S
DNA repair 2018 Jun-Jul;66-67:1-10
DNA repair 2018 Jun-Jul;66-67:1-10
The natural compound GL22, isolated from Ganoderma mushrooms, suppresses tumor growth by altering lipid metabolism and triggering cell death.
Liu G, Wang K, Kuang S, Cao R, Bao L, Liu R, Liu H, Sun C
Cell death & disease 2018 Jun 7;9(6):689
Cell death & disease 2018 Jun 7;9(6):689
Metformin ameliorates TGF-β1-induced osteoblastic differentiation of human aortic valve interstitial cells by inhibiting β-catenin signaling.
Liu F, Chu C, Wei Q, Shi J, Li H, Dong N
Biochemical and biophysical research communications 2018 Jun 7;500(3):710-716
Biochemical and biophysical research communications 2018 Jun 7;500(3):710-716
HEV ORF3 downregulates TLR7 to inhibit the generation of type I interferon via impairment of multiple signaling pathways.
Lei Q, Li L, Zhang S, Li T, Zhang X, Ding X, Qin B
Scientific reports 2018 Jun 5;8(1):8585
Scientific reports 2018 Jun 5;8(1):8585
Integrin αvβ3-associated DAAM1 is essential for collagen-induced invadopodia extension and cell haptotaxis in breast cancer cells.
Yan T, Zhang A, Shi F, Chang F, Mei J, Liu Y, Zhu Y
The Journal of biological chemistry 2018 Jun 29;293(26):10172-10185
The Journal of biological chemistry 2018 Jun 29;293(26):10172-10185
Traditional Chinese medication Tongxinluo attenuates apoptosis in ox-LDL-stimulated macrophages by enhancing Beclin-1-induced autophagy.
Chen Y, Li M, Zhang Y, Di M, Chen W, Liu X, Yu F, Wang H, Zhen X, Zhang M
Biochemical and biophysical research communications 2018 Jun 22;501(2):336-342
Biochemical and biophysical research communications 2018 Jun 22;501(2):336-342
Carbon monoxide-releasing molecule-3 protects against ischemic stroke by suppressing neuroinflammation and alleviating blood-brain barrier disruption.
Wang J, Zhang D, Fu X, Yu L, Lu Z, Gao Y, Liu X, Man J, Li S, Li N, Chen X, Hong M, Yang Q, Wang J
Journal of neuroinflammation 2018 Jun 21;15(1):188
Journal of neuroinflammation 2018 Jun 21;15(1):188
4EHP-independent repression of endogenous mRNAs by the RNA-binding protein GIGYF2.
Amaya Ramirez CC, Hubbe P, Mandel N, Béthune J
Nucleic acids research 2018 Jun 20;46(11):5792-5808
Nucleic acids research 2018 Jun 20;46(11):5792-5808
Deer thymosin beta 10 functions as a novel factor for angiogenesis and chondrogenesis during antler growth and regeneration.
Zhang W, Chu W, Liu Q, Coates D, Shang Y, Li C
Stem cell research & therapy 2018 Jun 19;9(1):166
Stem cell research & therapy 2018 Jun 19;9(1):166
Oxidative stress-mediated autophagic cell death participates in the neurotoxic effect on SH-SY5Y cells induced by excessive iodide.
Liu H, Wang L, Zeng Q, Zhao L, Cui Y, Hou C, Zhang B, Zhang Z, Zhang S, Chen X, Wang A
Environmental toxicology 2018 Jun 19;
Environmental toxicology 2018 Jun 19;
SPG6 supports development of acute myeloid leukemia by regulating BMPR2-Smad-Bcl-2/Bcl-xl signaling.
Chen J, Li C, Zhan R, Yin Y
Biochemical and biophysical research communications 2018 Jun 18;501(1):220-225
Biochemical and biophysical research communications 2018 Jun 18;501(1):220-225
PHF5A Epigenetically Inhibits Apoptosis to Promote Breast Cancer Progression.
Zheng YZ, Xue MZ, Shen HJ, Li XG, Ma D, Gong Y, Liu YR, Qiao F, Xie HY, Lian B, Sun WL, Zhao HY, Yao L, Zuo WJ, Li DQ, Wang P, Hu X, Shao ZM
Cancer research 2018 Jun 15;78(12):3190-3206
Cancer research 2018 Jun 15;78(12):3190-3206
RBM4 Modulates Radial Migration via Alternative Splicing of Dab1 during Cortex Development.
D D, Hung KY, Tarn WY
Molecular and cellular biology 2018 Jun 15;38(12)
Molecular and cellular biology 2018 Jun 15;38(12)
Reversal of reserpine-induced depression and cognitive disorder in zebrafish by sertraline and Traditional Chinese Medicine (TCM).
Zhang S, Liu X, Sun M, Zhang Q, Li T, Li X, Xu J, Zhao X, Chen D, Feng X
Behavioral and brain functions : BBF 2018 Jun 14;14(1):13
Behavioral and brain functions : BBF 2018 Jun 14;14(1):13
Exosomes released by hepatocarcinoma cells endow adipocytes with tumor-promoting properties.
Wang S, Xu M, Li X, Su X, Xiao X, Keating A, Zhao RC
Journal of hematology & oncology 2018 Jun 14;11(1):82
Journal of hematology & oncology 2018 Jun 14;11(1):82
Downregulation of HS6ST2 by miR-23b-3p enhances matrix degradation through p38 MAPK pathway in osteoarthritis.
Guo Y, Min Z, Jiang C, Wang W, Yan J, Xu P, Xu K, Xu J, Sun M, Zhao Y, Hussain S, Zhang R, Wang Q, Han Y, Zhang F, Zhu W, Li D, Meng L, Sun J, Lu S
Cell death & disease 2018 Jun 13;9(6):699
Cell death & disease 2018 Jun 13;9(6):699
BAI1 Suppresses Medulloblastoma Formation by Protecting p53 from Mdm2-Mediated Degradation.
Zhu D, Osuka S, Zhang Z, Reichert ZR, Yang L, Kanemura Y, Jiang Y, You S, Zhang H, Devi NS, Bhattacharya D, Takano S, Gillespie GY, Macdonald T, Tan C, Nishikawa R, Nelson WG, Olson JJ, Van Meir EG
Cancer cell 2018 Jun 11;33(6):1004-1016.e5
Cancer cell 2018 Jun 11;33(6):1004-1016.e5
miR-675 promotes odontogenic differentiation of human dental pulp cells by epigenetic regulation of DLX3.
Zeng L, Zhao N, Li F, Han D, Liu Y, Liu H, Sun S, Wang Y, Feng H
Experimental cell research 2018 Jun 1;367(1):104-111
Experimental cell research 2018 Jun 1;367(1):104-111
HBeAg induces the expression of macrophage miR-155 to accelerate liver injury via promoting production of inflammatory cytokines.
Wang W, Bian H, Li F, Li X, Zhang D, Sun S, Song S, Zhu Q, Ren W, Qin C, Qi J
Cellular and molecular life sciences : CMLS 2018 Jul;75(14):2627-2641
Cellular and molecular life sciences : CMLS 2018 Jul;75(14):2627-2641
Furin promotes dendritic morphogenesis and learning and memory in transgenic mice.
Zhu B, Zhao L, Luo D, Xu D, Tan T, Dong Z, Tang Y, Min Z, Deng X, Sun F, Yan Z, Chen G
Cellular and molecular life sciences : CMLS 2018 Jul;75(13):2473-2488
Cellular and molecular life sciences : CMLS 2018 Jul;75(13):2473-2488
LGR5 promotes epithelial ovarian cancer proliferation, metastasis, and epithelial-mesenchymal transition through the Notch1 signaling pathway.
Liu W, Zhang J, Gan X, Shen F, Yang X, Du N, Xia D, Liu L, Qiao L, Pan J, Sun Y, Xi X
Cancer medicine 2018 Jul;7(7):3132-3142
Cancer medicine 2018 Jul;7(7):3132-3142
Farnesoid X receptor signaling activates the hepatic X-box binding protein 1 pathway in vitro and in mice.
Liu X, Guo GL, Kong B, Hilburn DB, Hubchak SC, Park S, LeCuyer B, Hsieh A, Wang L, Fang D, Green RM
Hepatology (Baltimore, Md.) 2018 Jul;68(1):304-316
Hepatology (Baltimore, Md.) 2018 Jul;68(1):304-316
Anti-fibrogenic Potential of Mesenchymal Stromal Cells in Treating Fibrosis in Crohn's Disease.
Lian L, Huang Q, Zhang L, Qin H, He X, He X, Ke J, Xie M, Lan P
Digestive diseases and sciences 2018 Jul;63(7):1821-1834
Digestive diseases and sciences 2018 Jul;63(7):1821-1834
Glycyrrhizin ameliorates atopic dermatitis-like symptoms through inhibition of HMGB1.
Wang Y, Zhang Y, Peng G, Han X
International immunopharmacology 2018 Jul;60:9-17
International immunopharmacology 2018 Jul;60:9-17
LncRNA MT1DP Aggravates Cadmium-Induced Oxidative Stress by Repressing the Function of Nrf2 and is Dependent on Interaction with miR-365.
Gao M, Li C, Xu M, Liu Y, Cong M, Liu S
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2018 Jul;5(7):1800087
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2018 Jul;5(7):1800087
BCL11A Down-Regulation Induces γ-Globin in Human β-Thalassemia Major Erythroid Cells.
Li J, Lai Y, Shi L
Hemoglobin 2018 Jul;42(4):225-230
Hemoglobin 2018 Jul;42(4):225-230
A proteomic approach reveals the differential protein expression in Drosophila melanogaster treated with red ginseng extract (Panax ginseng).
Liu QX, Zhang W, Wang J, Hou W, Wang YP
Journal of ginseng research 2018 Jul;42(3):343-351
Journal of ginseng research 2018 Jul;42(3):343-351
Fenretinide inhibits the proliferation and migration of human liver cancer HepG2 cells by downregulating the activation of myosin light chain kinase through the p38‑MAPK signaling pathway.
Zhang L, Huang D, Shao D, Liu H, Zhou Q, Gui S, Wei W, Wang Y
Oncology reports 2018 Jul;40(1):518-526
Oncology reports 2018 Jul;40(1):518-526
Programmed death ligand 1 promotes lymph node metastasis and glucose metabolism in cervical cancer by activating integrin β4/SNAI1/SIRT3 signaling pathway.
Wang S, Li J, Xie J, Liu F, Duan Y, Wu Y, Huang S, He X, Wang Z, Wu X
Oncogene 2018 Jul;37(30):4164-4180
Oncogene 2018 Jul;37(30):4164-4180
Estrogen-related receptor alpha is involved in Alzheimer's disease-like pathology.
Tang Y, Min Z, Xiang XJ, Liu L, Ma YL, Zhu BL, Song L, Tang J, Deng XJ, Yan Z, Chen GJ
Experimental neurology 2018 Jul;305:89-96
Experimental neurology 2018 Jul;305:89-96
The endosomal recycling of FgSnc1 by FgSnx41-FgSnx4 heterodimer is essential for polarized growth and pathogenicity in Fusarium graminearum.
Zheng W, Lin Y, Fang W, Zhao X, Lou Y, Wang G, Zheng H, Liang Q, Abubakar YS, Olsson S, Zhou J, Wang Z
The New phytologist 2018 Jul;219(2):654-671
The New phytologist 2018 Jul;219(2):654-671
Inhibition of Mitochondrial Fission Preserves Photoreceptors after Retinal Detachment.
She X, Lu X, Li T, Sun J, Liang J, Zhai Y, Yang S, Gu Q, Wei F, Zhu H, Wang F, Luo X, Sun X
The American journal of pathology 2018 Jul;188(7):1713-1722
The American journal of pathology 2018 Jul;188(7):1713-1722
Increased oxidative stress mediates the antitumor effect of PARP inhibition in ovarian cancer.
Hou D, Liu Z, Xu X, Liu Q, Zhang X, Kong B, Wei JJ, Gong Y, Shao C
Redox biology 2018 Jul;17:99-111
Redox biology 2018 Jul;17:99-111
Sulforaphane attenuates microglia-mediated neuronal necroptosis through down-regulation of MAPK/NF-κB signaling pathways in LPS-activated BV-2 microglia.
Qin S, Yang C, Huang W, Du S, Mai H, Xiao J, Lü T
Pharmacological research 2018 Jul;133:218-235
Pharmacological research 2018 Jul;133:218-235
Temporary inhibition of the plasminogen activator inhibits periosteal chondrogenesis and promotes periosteal osteogenesis during appendicular bone fracture healing.
Bravo D, Josephson AM, Bradaschia-Correa V, Wong MZ, Yim NL, Neibart SS, Lee SN, Huo J, Coughlin T, Mizrahi MM, Leucht P
Bone 2018 Jul;112:97-106
Bone 2018 Jul;112:97-106
BET bromodomain inhibitor JQ1 preferentially suppresses EBV-positive nasopharyngeal carcinoma cells partially through repressing c-Myc.
Li N, Yang L, Qi XK, Lin YX, Xie X, He GP, Feng QS, Liu LR, Xie X, Zeng YX, Feng L
Cell death & disease 2018 Jul 9;9(7):761
Cell death & disease 2018 Jul 9;9(7):761
SET1A-Mediated Mono-Methylation at K342 Regulates YAP Activation by Blocking Its Nuclear Export and Promotes Tumorigenesis.
Fang L, Teng H, Wang Y, Liao G, Weng L, Li Y, Wang X, Jin J, Jiao C, Chen L, Peng X, Chen J, Yang Y, Fang H, Han D, Li C, Jin X, Zhang S, Liu Z, Liu M, Wei Q, Liao L, Ge X, Zhao B, Zhou D, Qin HL, Zhou J, Wang P
Cancer cell 2018 Jul 9;34(1):103-118.e9
Cancer cell 2018 Jul 9;34(1):103-118.e9
Naringenin exhibits the protective effect on cardiac hypertrophy via EETs-PPARs activation in streptozocin-induced diabetic mice.
Zhang J, Qiu H, Huang J, Ding S, Huang B, Wu Q, Jiang Q
Biochemical and biophysical research communications 2018 Jul 7;502(1):55-61
Biochemical and biophysical research communications 2018 Jul 7;502(1):55-61
The exon 19-deleted EGFR undergoes ubiquitylation-mediated endocytic degradation via dynamin activity-dependent and -independent mechanisms.
Wang T, Zhang J, Wang S, Sun X, Wang D, Gao Y, Zhang Y, Xu L, Wu Y, Wu Y, Liu F, Liu X, Liu S, Zhang Y, Wang Y, Zou L, Liu H
Cell communication and signaling : CCS 2018 Jul 5;16(1):40
Cell communication and signaling : CCS 2018 Jul 5;16(1):40
Ketamine differentially restores diverse alterations of neuroligins in brain regions in a rat model of neuropathic pain-induced depression.
Pan W, Zhang GF, Li HH, Ji MH, Zhou ZQ, Li KY, Yang JJ
Neuroreport 2018 Jul 4;29(10):863-869
Neuroreport 2018 Jul 4;29(10):863-869
Tristetraprolin Overexpression in Gastric Cancer Cells Suppresses PD-L1 Expression and Inhibits Tumor Progression by Enhancing Antitumor Immunity.
Guo J, Qu H, Shan T, Chen Y, Chen Y, Xia J
Molecules and cells 2018 Jul 31;41(7):653-664
Molecules and cells 2018 Jul 31;41(7):653-664
Circular RNA IARS (circ-IARS) secreted by pancreatic cancer cells and located within exosomes regulates endothelial monolayer permeability to promote tumor metastasis.
Li J, Li Z, Jiang P, Peng M, Zhang X, Chen K, Liu H, Bi H, Liu X, Li X
Journal of experimental & clinical cancer research : CR 2018 Jul 31;37(1):177
Journal of experimental & clinical cancer research : CR 2018 Jul 31;37(1):177
PEI-Coated Fe₃O₄ Nanoparticles Enable Efficient Delivery of Therapeutic siRNA Targeting REST into Glioblastoma Cells.
Wang R, Degirmenci V, Xin H, Li Y, Wang L, Chen J, Hu X, Zhang D
International journal of molecular sciences 2018 Jul 31;19(8)
International journal of molecular sciences 2018 Jul 31;19(8)
Imbalanced LIMK1 and LIMK2 expression leads to human colorectal cancer progression and metastasis via promoting β-catenin nuclear translocation.
Zhang Y, Li A, Shi J, Fang Y, Gu C, Cai J, Lin C, Zhao L, Liu S
Cell death & disease 2018 Jul 3;9(7):749
Cell death & disease 2018 Jul 3;9(7):749
17β-estradiol upregulates IL6 expression through the ERβ pathway to promote lung adenocarcinoma progression.
Huang Q, Zhang Z, Liao Y, Liu C, Fan S, Wei X, Ai B, Xiong J
Journal of experimental & clinical cancer research : CR 2018 Jul 3;37(1):133
Journal of experimental & clinical cancer research : CR 2018 Jul 3;37(1):133
3-O-acetyl-11-keto-β-boswellic acid exerts anti-tumor effects in glioblastoma by arresting cell cycle at G2/M phase.
Li W, Liu J, Fu W, Zheng X, Ren L, Liu S, Wang J, Ji T, Du G
Journal of experimental & clinical cancer research : CR 2018 Jul 3;37(1):132
Journal of experimental & clinical cancer research : CR 2018 Jul 3;37(1):132
ZDHHC8 critically regulates seizure susceptibility in epilepsy.
Yang Q, Zheng F, Hu Y, Yang Y, Li Y, Chen G, Wang W, He M, Zhou R, Ma Y, Xu D, Tian X, Gao X, Wang Q, Wang X
Cell death & disease 2018 Jul 23;9(8):795
Cell death & disease 2018 Jul 23;9(8):795
FoxM1 repression during human aging leads to mitotic decline and aneuploidy-driven full senescence.
Macedo JC, Vaz S, Bakker B, Ribeiro R, Bakker PL, Escandell JM, Ferreira MG, Medema R, Foijer F, Logarinho E
Nature communications 2018 Jul 19;9(1):2834
Nature communications 2018 Jul 19;9(1):2834
Long non-coding RNA PVT1 promotes malignancy in human endometrial carcinoma cells through negative regulation of miR-195-5p.
Kong F, Ma J, Yang H, Yang D, Wang C, Ma X
Biochimica et biophysica acta. Molecular cell research 2018 Jul 19;
Biochimica et biophysica acta. Molecular cell research 2018 Jul 19;
Comparison of the effects of selenomethionine and selenium-enriched yeast in the triple-transgenic mouse model of Alzheimer's disease.
Zhang ZH, Wu QY, Chen C, Zheng R, Chen Y, Ni JZ, Song GL
Food & function 2018 Jul 17;9(7):3965-3973
Food & function 2018 Jul 17;9(7):3965-3973
Unique BIR domain sets determine inhibitor of apoptosis protein-driven cell death and NOD2 complex signal specificity.
Chirieleison SM, Rathkey JK, Abbott DW
Science signaling 2018 Jul 17;11(539)
Science signaling 2018 Jul 17;11(539)
Aspirin is Involved in the Cell Cycle Arrest, Apoptosis, Cell Migration, and Invasion of Oral Squamous Cell Carcinoma.
Zhang X, Feng H, Li Z, Guo J, Li M
International journal of molecular sciences 2018 Jul 12;19(7)
International journal of molecular sciences 2018 Jul 12;19(7)
TNFRSF19 Inhibits TGFβ Signaling through Interaction with TGFβ Receptor Type I to Promote Tumorigenesis.
Deng C, Lin YX, Qi XK, He GP, Zhang Y, Zhang HJ, Xu M, Feng QS, Bei JX, Zeng YX, Feng L
Cancer research 2018 Jul 1;78(13):3469-3483
Cancer research 2018 Jul 1;78(13):3469-3483
Protective effect of dioscin against thioacetamide-induced acute liver injury via FXR/AMPK signaling pathway in vivo.
Zheng L, Yin L, Xu L, Qi Y, Li H, Xu Y, Han X, Liu K, Peng J
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Jan;97:481-488
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Jan;97:481-488
Stachydrine ameliorates carbon tetrachloride-induced hepatic fibrosis by inhibiting inflammation, oxidative stress and regulating MMPs/TIMPs system in rats.
Zhang J, Yang A, Wu Y, Guan W, Xiong B, Peng X, Wei X, Chen C, Liu Z
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Jan;97:1586-1594
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Jan;97:1586-1594
β-Arrestin-1 deficiency ameliorates renal interstitial fibrosis by blocking Wnt1/β-catenin signaling in mice.
Xu H, Li Q, Liu J, Zhu J, Li L, Wang Z, Zhang Y, Sun Y, Sun J, Wang R, Yi F
Journal of molecular medicine (Berlin, Germany) 2018 Jan;96(1):97-109
Journal of molecular medicine (Berlin, Germany) 2018 Jan;96(1):97-109
Limb remote ischemia per-conditioning protects the heart against ischemia-reperfusion injury through the opioid system in rats.
Zhang L, Guo H, Yuan F, Hong ZC, Tian YM, Zhang XJ, Zhang Y
Canadian journal of physiology and pharmacology 2018 Jan;96(1):68-75
Canadian journal of physiology and pharmacology 2018 Jan;96(1):68-75
Propofol attenuates myocardial ischemia reperfusion injury partly through inhibition of resident cardiac mast cell activation.
Yu X, Sun X, Zhao M, Hou Y, Li J, Yu J, Hou Y
International immunopharmacology 2018 Jan;54:267-274
International immunopharmacology 2018 Jan;54:267-274
Vimentin is a crucial target for anti-metastasis therapy of nasopharyngeal carcinoma.
Wang W, Yi M, Zhang R, Li J, Chen S, Cai J, Zeng Z, Li X, Xiong W, Wang L, Li G, Xiang B
Molecular and cellular biochemistry 2018 Jan;438(1-2):47-57
Molecular and cellular biochemistry 2018 Jan;438(1-2):47-57
Knockdown of eukaryotic translation initiation factor 3 subunit D (eIF3D) inhibits proliferation of acute myeloid leukemia cells.
Liu GZ, Liu JZ, Li XQ, Zhang L, Li SJ, Xiao TW, Wang JX, Li GY, Liu Y
Molecular and cellular biochemistry 2018 Jan;438(1-2):191-198
Molecular and cellular biochemistry 2018 Jan;438(1-2):191-198
Proteasome inhibitor bortezomib is a novel therapeutic agent for focal radiation-induced osteoporosis.
Chandra A, Wang L, Young T, Zhong L, Tseng WJ, Levine MA, Cengel K, Liu XS, Zhang Y, Pignolo RJ, Qin L
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2018 Jan;32(1):52-62
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2018 Jan;32(1):52-62
Localization of endogenous amyloid-β to the coeruleo-cortical pathway: consequences of noradrenergic depletion.
Ross JA, Reyes BAS, Thomas SA, Van Bockstaele EJ
Brain structure & function 2018 Jan;223(1):267-284
Brain structure & function 2018 Jan;223(1):267-284
Down-regulation of miR-10a-5p in synoviocytes contributes to TBX5-controlled joint inflammation.
Hussain N, Zhu W, Jiang C, Xu J, Wu X, Geng M, Hussain S, Cai Y, Xu K, Xu P, Han Y, Sun J, Meng L, Lu S
Journal of cellular and molecular medicine 2018 Jan;22(1):241-250
Journal of cellular and molecular medicine 2018 Jan;22(1):241-250
Identification of two antiviral inhibitors targeting 3C-like serine/3C-like protease of porcine reproductive and respiratory syndrome virus and porcine epidemic diarrhea virus.
Shi Y, Lei Y, Ye G, Sun L, Fang L, Xiao S, Fu ZF, Yin P, Song Y, Peng G
Veterinary microbiology 2018 Jan;213:114-122
Veterinary microbiology 2018 Jan;213:114-122
IgE induces hypotension in asthma mice by down-regulating vascular NCX1 expression through activating MiR-212-5p.
Zhao H, Song X, Yan L, Ren M, Cui X, Li Y, Gao R, Zhang W, Liu M, Liu B, Hu Y, Wang J
Biochimica et biophysica acta. Molecular basis of disease 2018 Jan;1864(1):189-196
Biochimica et biophysica acta. Molecular basis of disease 2018 Jan;1864(1):189-196
Cell Cycle-Dependent Tumor Engraftment and Migration Are Enabled by Aurora-A.
Chu TLH, Connell M, Zhou L, He Z, Won J, Chen H, Rahavi SMR, Mohan P, Nemirovsky O, Fotovati A, Pujana MA, Reid GSD, Nielsen TO, Pante N, Maxwell CA
Molecular cancer research : MCR 2018 Jan;16(1):16-31
Molecular cancer research : MCR 2018 Jan;16(1):16-31
Sphingomyelin synthase 2 overexpression promotes cisplatin-induced apoptosis of HepG2 cells.
Luo S, Pan Z, Liu S, Yuan S, Yan N
Oncology letters 2018 Jan;15(1):483-488
Oncology letters 2018 Jan;15(1):483-488
PTEN-L promotes type I interferon responses and antiviral immunity.
Cao Y, Wang H, Yang L, Zhang Z, Li C, Yuan X, Bu L, Chen L, Chen Y, Li CM, Guo D
Cellular & molecular immunology 2018 Jan;15(1):48-57
Cellular & molecular immunology 2018 Jan;15(1):48-57
20-HETE regulated PSMB5 expression via TGF-β/Smad signaling pathway.
Lai G, Sun R, Wu J, Zhang B, Zhao Y
Prostaglandins & other lipid mediators 2018 Jan;134:123-130
Prostaglandins & other lipid mediators 2018 Jan;134:123-130
Icariin, a flavonoid with anti-cancer effects, alleviated paclitaxel-induced neuropathic pain in a SIRT1-dependent manner.
Gui Y, Zhang J, Chen L, Duan S, Tang J, Xu W, Li A
Molecular pain 2018 Jan-Dec;14:1744806918768970
Molecular pain 2018 Jan-Dec;14:1744806918768970
Downregulation of N(6)-methyladenosine binding YTHDF2 protein mediated by miR-493-3p suppresses prostate cancer by elevating N(6)-methyladenosine levels.
Li J, Meng S, Xu M, Wang S, He L, Xu X, Wang X, Xie L
Oncotarget 2018 Jan 9;9(3):3752-3764
Oncotarget 2018 Jan 9;9(3):3752-3764
Inhibition of insulin resistance by PGE1 via autophagy-dependent FGF21 pathway in diabetic nephropathy.
Wei W, An XR, Jin SJ, Li XX, Xu M
Scientific reports 2018 Jan 8;8(1):9
Scientific reports 2018 Jan 8;8(1):9
Genomic and Epigenomic Profiling of High-Risk Intestinal Metaplasia Reveals Molecular Determinants of Progression to Gastric Cancer.
Huang KK, Ramnarayanan K, Zhu F, Srivastava S, Xu C, Tan ALK, Lee M, Tay S, Das K, Xing M, Fatehullah A, Alkaff SMF, Lim TKH, Lee J, Ho KY, Rozen SG, Teh BT, Barker N, Chia CK, Khor C, Ooi CJ, Fock KM, So J, Lim WC, Ling KL, Ang TL, Wong A, Rao J, Rajnakova A, Lim LG, Yap WM, Teh M, Yeoh KG, Tan P
Cancer cell 2018 Jan 8;33(1):137-150.e5
Cancer cell 2018 Jan 8;33(1):137-150.e5
Neutrophil extracellular traps contribute to the pathogenesis of acid-aspiration-induced ALI/ARDS.
Li H, Zhou X, Tan H, Hu Y, Zhang L, Liu S, Dai M, Li Y, Li Q, Mao Z, Pan P, Su X, Hu C
Oncotarget 2018 Jan 5;9(2):1772-1784
Oncotarget 2018 Jan 5;9(2):1772-1784
Protective Effects of Leukemia Inhibitory Factor on Retinal Vasculature and Cells in Streptozotocin-induced Diabetic Mice.
Yang XF, Huang YX, Lan M, Zhang TR, Zhou J
Chinese medical journal 2018 Jan 5;131(1):75-81
Chinese medical journal 2018 Jan 5;131(1):75-81
Antidiabetic activities of entagenic acid in type 2 diabetic db/db mice and L6 myotubes via AMPK/GLUT4 pathway.
Xiong H, Zhang S, Zhao Z, Zhao P, Chen L, Mei Z
Journal of ethnopharmacology 2018 Jan 30;211:366-374
Journal of ethnopharmacology 2018 Jan 30;211:366-374
LncRNA LOC730101 promotes osteosarcoma cell survival under energy stress.
Cheng G, Li B, Sun X, Cao Z, Zhang G, Zhao Z, Zhao Y, Yu Q, Liu W
Biochemical and biophysical research communications 2018 Jan 29;496(1):1-6
Biochemical and biophysical research communications 2018 Jan 29;496(1):1-6
Hydrogen-water ameliorates radiation-induced gastrointestinal toxicity via MyD88's effects on the gut microbiota.
Xiao HW, Li Y, Luo D, Dong JL, Zhou LX, Zhao SY, Zheng QS, Wang HC, Cui M, Fan SJ
Experimental & molecular medicine 2018 Jan 26;50(1):e433
Experimental & molecular medicine 2018 Jan 26;50(1):e433
Gentiopicroside ameliorates bleomycin-induced pulmonary fibrosis in mice via inhibiting inflammatory and fibrotic process.
Chen C, Wang YY, Wang YX, Cheng MQ, Yin JB, Zhang X, Hong ZP
Biochemical and biophysical research communications 2018 Jan 22;495(4):2396-2403
Biochemical and biophysical research communications 2018 Jan 22;495(4):2396-2403
C-MYC and BCL-2 mediate YAP-regulated tumorigenesis in OSCC.
Chen X, Gu W, Wang Q, Fu X, Wang Y, Xu X, Wen Y
Oncotarget 2018 Jan 2;9(1):668-679
Oncotarget 2018 Jan 2;9(1):668-679
Comprehensive Genomic Characterization of RNA-Binding Proteins across Human Cancers.
Wang ZL, Li B, Luo YX, Lin Q, Liu SR, Zhang XQ, Zhou H, Yang JH, Qu LH
Cell reports 2018 Jan 2;22(1):286-298
Cell reports 2018 Jan 2;22(1):286-298
The Potential Roles of the Apoptosis-Related Protein PDRG1 in Diapause Embryo Restarting of Artemia sinica.
Zhang W, Yao F, Zhang H, Li N, Zou X, Sui L, Hou L
International journal of molecular sciences 2018 Jan 2;19(1)
International journal of molecular sciences 2018 Jan 2;19(1)
SOCE induced calcium overload regulates autophagy in acute pancreatitis via calcineurin activation.
Zhu ZD, Yu T, Liu HJ, Jin J, He J
Cell death & disease 2018 Jan 19;9(2):50
Cell death & disease 2018 Jan 19;9(2):50
IcarisideII improves left ventricular remodeling in spontaneously hypertensive rats by inhibiting the ASK1-JNK/p38 signaling pathway.
Wu Y, Qian Z, Fu S, Yue Y, Li Y, Sun R, Huang B, Yang D
European journal of pharmacology 2018 Jan 15;819:68-79
European journal of pharmacology 2018 Jan 15;819:68-79
FBXO2, a novel marker for metastasis in human gastric cancer.
Sun X, Wang T, Guan ZR, Zhang C, Chen Y, Jin J, Hua D
Biochemical and biophysical research communications 2018 Jan 15;495(3):2158-2164
Biochemical and biophysical research communications 2018 Jan 15;495(3):2158-2164
SIRT3 prevents angiotensin II-induced renal tubular epithelial-mesenchymal transition by ameliorating oxidative stress and mitochondrial dysfunction.
He P, Li Z, Yue Z, Gao H, Feng G, Wang P, Huang Y, Luo W, Hong H, Liang L, Chen S, Liu P
Molecular and cellular endocrinology 2018 Jan 15;460:1-13
Molecular and cellular endocrinology 2018 Jan 15;460:1-13
Exosomes derived from imatinib-resistant chronic myeloid leukemia cells mediate a horizontal transfer of drug-resistant trait by delivering miR-365.
Min QH, Wang XZ, Zhang J, Chen QG, Li SQ, Liu XQ, Li J, Liu J, Yang WM, Jiang YH, Xu YM, Lin J, Gao QF, Sun F, Zhang L, Huang B
Experimental cell research 2018 Jan 15;362(2):386-393
Experimental cell research 2018 Jan 15;362(2):386-393
Co-expression analysis revealed PTCH1-3'UTR promoted cell migration and invasion by activating miR-101-3p/SLC39A6 axis in non-small cell lung cancer: implicating the novel function of PTCH1.
Wan X, Kong Z, Chu K, Yi C, Hu J, Qin R, Zhao C, Fu F, Wu H, Li Y, Huang Y
Oncotarget 2018 Jan 12;9(4):4798-4813
Oncotarget 2018 Jan 12;9(4):4798-4813
Inhibition of autophagy-attenuated calcium oxalate crystal-induced renal tubular epithelial cell injury in vivo and in vitro.
Liu Y, Li D, He Z, Liu Q, Wu J, Guan X, Tao Z, Deng Y
Oncotarget 2018 Jan 12;9(4):4571-4582
Oncotarget 2018 Jan 12;9(4):4571-4582
MicroRNA-200a confers chemoresistance by antagonizing TP53INP1 and YAP1 in human breast cancer.
Yu SJ, Yang L, Hong Q, Kuang XY, Di GH, Shao ZM
BMC cancer 2018 Jan 12;18(1):74
BMC cancer 2018 Jan 12;18(1):74
Pharmacological Investigation of the Anti-Inflammation and Anti-Oxidation Activities of Diallyl Disulfide in a Rat Emphysema Model Induced by Cigarette Smoke Extract.
Liu Y, Li A, Feng X, Sun X, Zhu X, Zhao Z
Nutrients 2018 Jan 12;10(1)
Nutrients 2018 Jan 12;10(1)
GBP3 promotes glioma cell proliferation via SQSTM1/p62-ERK1/2 axis.
Xu H, Sun L, Zheng Y, Yu S, Ou-Yang J, Han H, Dai X, Yu X, Li M, Lan Q
Biochemical and biophysical research communications 2018 Jan 1;495(1):446-453
Biochemical and biophysical research communications 2018 Jan 1;495(1):446-453
Protein Kinase A/CREB Signaling Prevents Adriamycin-Induced Podocyte Apoptosis via Upregulation of Mitochondrial Respiratory Chain Complexes.
Xie K, Zhu M, Xiang P, Chen X, Kasimumali A, Lu R, Wang Q, Mou S, Ni Z, Gu L, Pang H
Molecular and cellular biology 2018 Jan 1;38(1)
Molecular and cellular biology 2018 Jan 1;38(1)
MiR-208a-3p aggravates autophagy through the PDCD4-ATG5 pathway in Ang II-induced H9c2 cardiomyoblasts.
Wang L, Ye N, Lian X, Peng F, Zhang H, Gong H
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Feb;98:1-8
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Feb;98:1-8
The E3 ubiquitin ligase MuRF2 attenuates LPS-induced macrophage activation by inhibiting production of inflammatory cytokines and migration.
Bian H, Gao S, Zhang D, Zhao Q, Li F, Li X, Sun S, Song S, Li T, Zhu Q, Ren W, Qin C, Qi J
FEBS open bio 2018 Feb;8(2):234-243
FEBS open bio 2018 Feb;8(2):234-243
Exosomes From Adipose-Derived Stem Cells Attenuate Adipose Inflammation and Obesity Through Polarizing M2 Macrophages and Beiging in White Adipose Tissue.
Zhao H, Shang Q, Pan Z, Bai Y, Li Z, Zhang H, Zhang Q, Guo C, Zhang L, Wang Q
Diabetes 2018 Feb;67(2):235-247
Diabetes 2018 Feb;67(2):235-247
Speckle-Type POZ Protein Down-Regulates Matrix Metalloproteinase 2 Expression via Sp1/PI3K/Akt Signaling Pathway in Colorectal Cancer.
Zhang S, Xiao J, Chai Y, Hong Z, Liu Z, Yuan R, Luo Z, Zhou X, Lucero-Prisno DE III, Huang K
Digestive diseases and sciences 2018 Feb;63(2):395-402
Digestive diseases and sciences 2018 Feb;63(2):395-402
Proteasome-mediated degradation of collagen III by cortisol in amnion fibroblasts.
Mi Y, Wang W, Lu J, Zhang C, Wang Y, Ying H, Sun K
Journal of molecular endocrinology 2018 Feb;60(2):45-54
Journal of molecular endocrinology 2018 Feb;60(2):45-54
Telbivudine attenuates UUO-induced renal fibrosis via TGF-β/Smad and NF-κB signaling.
Chen J, Li D
International immunopharmacology 2018 Feb;55:1-8
International immunopharmacology 2018 Feb;55:1-8
Clinical significance of C/D box small nucleolar RNA U76 as an oncogene and a prognostic biomarker in hepatocellular carcinoma.
Wu L, Chang L, Wang H, Ma W, Peng Q, Yuan Y
Clinics and research in hepatology and gastroenterology 2018 Feb;42(1):82-91
Clinics and research in hepatology and gastroenterology 2018 Feb;42(1):82-91
Fungal β-Glucan Activates the NLRP3 Inflammasome in Human Bronchial Epithelial Cells Through ROS Production.
Huang Y, Hua M, Cui X
Inflammation 2018 Feb;41(1):164-173
Inflammation 2018 Feb;41(1):164-173
NLRC5 deficiency ameliorates diabetic nephropathy through alleviating inflammation.
Luan P, Zhuang J, Zou J, Li H, Shuai P, Xu X, Zhao Y, Kou W, Ji S, Peng A, Xu Y, Su Q, Jian W, Peng W
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2018 Feb;32(2):1070-1084
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2018 Feb;32(2):1070-1084
Coordinated transcription of ANRIL and P16 genes is silenced by P16 DNA methylation.
Gan Y, Ma W, Wang X, Qiao J, Zhang B, Cui C, Liu Z, Deng D
Chinese journal of cancer research = Chung-kuo yen cheng yen chiu 2018 Feb;30(1):93-103
Chinese journal of cancer research = Chung-kuo yen cheng yen chiu 2018 Feb;30(1):93-103
Ephrin receptor A2 is an epithelial cell receptor for Epstein-Barr virus entry.
Zhang H, Li Y, Wang HB, Zhang A, Chen ML, Fang ZX, Dong XD, Li SB, Du Y, Xiong D, He JY, Li MZ, Liu YM, Zhou AJ, Zhong Q, Zeng YX, Kieff E, Zhang Z, Gewurz BE, Zhao B, Zeng MS
Nature microbiology 2018 Feb;3(2):1-8
Nature microbiology 2018 Feb;3(2):1-8
Intrinsic antimicrobial properties of silk spun by genetically modified silkworm strains.
Saviane A, Romoli O, Bozzato A, Freddi G, Cappelletti C, Rosini E, Cappellozza S, Tettamanti G, Sandrelli F
Transgenic research 2018 Feb;27(1):87-101
Transgenic research 2018 Feb;27(1):87-101
Recurrent ECSIT mutation encoding V140A triggers hyperinflammation and promotes hemophagocytic syndrome in extranodal NK/T cell lymphoma.
Wen H, Ma H, Cai Q, Lin S, Lei X, He B, Wu S, Wang Z, Gao Y, Liu W, Liu W, Tao Q, Long Z, Yan M, Li D, Kelley KW, Yang Y, Huang H, Liu Q
Nature medicine 2018 Feb;24(2):154-164
Nature medicine 2018 Feb;24(2):154-164
The long non-coding RNA PVT1 represses ANGPTL4 transcription through binding with EZH2 in trophoblast cell.
Xu Y, Lian Y, Zhang Y, Huang S, Zuo Q, Yang N, Chen Y, Wu D, Sun L
Journal of cellular and molecular medicine 2018 Feb;22(2):1272-1282
Journal of cellular and molecular medicine 2018 Feb;22(2):1272-1282
Quantitative proteomics study of host response to virulent and attenuated pseudorabies virus infection in mouse brain.
Zeng HL, Yu FL, Zhang Z, Yang Q, Jin S, He X, Chen X, Shen Y, Cheng L, Guo L, Xu F
Biochimica et biophysica acta. Proteins and proteomics 2018 Feb;1866(2):307-315
Biochimica et biophysica acta. Proteins and proteomics 2018 Feb;1866(2):307-315
SATB2 suppresses non-small cell lung cancer invasiveness by G9a.
Ma YN, Zhang HY, Fei LR, Zhang MY, Wang CC, Luo Y, Han YC
Clinical and experimental medicine 2018 Feb;18(1):37-44
Clinical and experimental medicine 2018 Feb;18(1):37-44
Propofol protects against endotoxin-induced myocardial injury by inhibiting NF-κB-mediated inflammation.
Yang Z, Cheng F, Yan G, Xiong L, Liu H
Experimental and therapeutic medicine 2018 Feb;15(2):2032-2036
Experimental and therapeutic medicine 2018 Feb;15(2):2032-2036
Annexin A10 contributes to chronic constrictive injury-induced pain through activating ERK1/2 signalling in rats.
Li F, Xue ZY, Liu X, Bai G, Wang YL
The International journal of neuroscience 2018 Feb;128(2):125-132
The International journal of neuroscience 2018 Feb;128(2):125-132
Decreased expression of hepatic cytochrome P450 1A2 (CYP1A2) in a chronic intermittent hypoxia mouse model.
Zhang XB, Zeng YM, Chen XY, Zhang YX, Ding JZ, Xue C
Journal of thoracic disease 2018 Feb;10(2):825-834
Journal of thoracic disease 2018 Feb;10(2):825-834
Fasudil increases temozolomide sensitivity and suppresses temozolomide-resistant glioma growth via inhibiting ROCK2/ABCG2.
Zhang X, Liu X, Zhou W, Yang M, Ding Y, Wang Q, Hu R
Cell death & disease 2018 Feb 7;9(2):190
Cell death & disease 2018 Feb 7;9(2):190
Photosensitization of A2E triggers telomere dysfunction and accelerates retinal pigment epithelium senescence.
Wang J, Feng Y, Han P, Wang F, Luo X, Liang J, Sun X, Ye J, Lu Y, Sun X
Cell death & disease 2018 Feb 7;9(2):178
Cell death & disease 2018 Feb 7;9(2):178
Nicotine promotes atherosclerosis via ROS-NLRP3-mediated endothelial cell pyroptosis.
Wu X, Zhang H, Qi W, Zhang Y, Li J, Li Z, Lin Y, Bai X, Liu X, Chen X, Yang H, Xu C, Zhang Y, Yang B
Cell death & disease 2018 Feb 7;9(2):171
Cell death & disease 2018 Feb 7;9(2):171
Flavagline analog FL3 induces cell cycle arrest in urothelial carcinoma cell of the bladder by inhibiting the Akt/PHB interaction to activate the GADD45α pathway.
Yuan G, Chen X, Liu Z, Wei W, Shu Q, Abou-Hamdan H, Jiang L, Li X, Chen R, Désaubry L, Zhou F, Xie D
Journal of experimental & clinical cancer research : CR 2018 Feb 7;37(1):21
Journal of experimental & clinical cancer research : CR 2018 Feb 7;37(1):21
Silencing Ras-Related C3 Botulinum Toxin Substrate 1 Inhibits Growth and Migration of Hypopharyngeal Squamous Cell Carcinoma via the P38 Mitogen-Activated Protein Kinase Signaling Pathway.
Cheng H, Wang W, Wang G, Wang A, Du L, Lou W
Medical science monitor : international medical journal of experimental and clinical research 2018 Feb 7;24:768-781
Medical science monitor : international medical journal of experimental and clinical research 2018 Feb 7;24:768-781
N-oleoylethanolamide suppresses intimal hyperplasia after balloon injury in rats through AMPK/PPARα pathway.
Zhao Y, Liu Y, Jing Z, Peng L, Jin P, Lin Y, Zhou Y, Yang L, Ren J, Xie Q, Jin X
Biochemical and biophysical research communications 2018 Feb 5;496(2):415-421
Biochemical and biophysical research communications 2018 Feb 5;496(2):415-421
Estrogen directly stimulates LHb expression at the pituitary level during puberty in female zebrafish.
Li G, Tang H, Chen Y, Yin Y, Ogawa S, Liu M, Guo Y, Qi X, Liu Y, Parhar IS, Liu X, Lin H
Molecular and cellular endocrinology 2018 Feb 5;461:1-11
Molecular and cellular endocrinology 2018 Feb 5;461:1-11
l-Menthol alleviates cigarette smoke extract induced lung injury in rats by inhibiting oxidative stress and inflammation via nuclear factor kappa B, p38 MAPK and Nrf2 signalling pathways.
Liu Y, Li A, Feng X, Jiang X, Sun X, Huang W, Zhu X, Zhao Z
RSC advances 2018 Feb 28;8(17):9353-9363
RSC advances 2018 Feb 28;8(17):9353-9363
Ginsenoside Rg3 sensitizes hypoxic lung cancer cells to cisplatin via blocking of NF-κB mediated epithelial-mesenchymal transition and stemness.
Wang J, Tian L, Khan MN, Zhang L, Chen Q, Zhao Y, Yan Q, Fu L, Liu J
Cancer letters 2018 Feb 28;415:73-85
Cancer letters 2018 Feb 28;415:73-85
Comprehensive integrative analyses identify GLT8D1 and CSNK2B as schizophrenia risk genes.
Yang CP, Li X, Wu Y, Shen Q, Zeng Y, Xiong Q, Wei M, Chen C, Liu J, Huo Y, Li K, Xue G, Yao YG, Zhang C, Li M, Chen Y, Luo XJ
Nature communications 2018 Feb 26;9(1):838
Nature communications 2018 Feb 26;9(1):838
Liver-specific deletion of TSHR inhibits hepatic lipid accumulation in mice.
Zhou L, Wu K, Zhang L, Gao L, Chen S
Biochemical and biophysical research communications 2018 Feb 26;497(1):39-45
Biochemical and biophysical research communications 2018 Feb 26;497(1):39-45
PIM1 mediates epithelial-mesenchymal transition by targeting Smads and c-Myc in the nucleus and potentiates clear-cell renal-cell carcinoma oncogenesis.
Zhao B, Liu L, Mao J, Zhang Z, Wang Q, Li Q
Cell death & disease 2018 Feb 22;9(3):307
Cell death & disease 2018 Feb 22;9(3):307
High-fat Diet Mediates Anxiolytic-like Behaviors in a Time-dependent Manner Through the Regulation of SIRT1 in the Brain.
Xu L, Xu S, Lin L, Gu X, Fu C, Fang Y, Li X, Wang X
Neuroscience 2018 Feb 21;372:237-245
Neuroscience 2018 Feb 21;372:237-245
GRK5 functions as an oncogenic factor in non-small-cell lung cancer.
Jiang LP, Fan SQ, Xiong QX, Zhou YC, Yang ZZ, Li GF, Huang YC, Wu MG, Shen QS, Liu K, Yang CP, Chen YB
Cell death & disease 2018 Feb 20;9(3):295
Cell death & disease 2018 Feb 20;9(3):295
TRAF6 regulates EGF-induced cell transformation and cSCC malignant phenotype through CD147/EGFR.
Zhang X, Wu L, Xiao T, Tang L, Jia X, Guo Y, Zhang J, Li J, He Y, Su J, Zhao S, Tao J, Zhou J, Chen X, Peng C
Oncogenesis 2018 Feb 20;7(2):17
Oncogenesis 2018 Feb 20;7(2):17
Interferon-alpha enhances the antitumour activity of EGFR-targeted therapies by upregulating RIG-I in head and neck squamous cell carcinoma.
Ma H, Jin S, Yang W, Zhou G, Zhao M, Fang S, Zhang Z, Hu J
British journal of cancer 2018 Feb 20;118(4):509-521
British journal of cancer 2018 Feb 20;118(4):509-521
Upregulation of kinesin family member 4A enhanced cell proliferation via activation of Akt signaling and predicted a poor prognosis in hepatocellular carcinoma.
Huang Y, Wang H, Lian Y, Wu X, Zhou L, Wang J, Deng M, Huang Y
Cell death & disease 2018 Feb 2;9(2):141
Cell death & disease 2018 Feb 2;9(2):141
NIT1 suppresses tumour proliferation by activating the TGFβ1-Smad2/3 signalling pathway in colorectal cancer.
Lin C, Zhang J, Lu Y, Li X, Zhang W, Zhang W, Lin W, Zheng L, Li X
Cell death & disease 2018 Feb 15;9(3):263
Cell death & disease 2018 Feb 15;9(3):263
Molecular adaptations of adipose tissue to 6 weeks of morning fasting vs. daily breakfast consumption in lean and obese adults.
Gonzalez JT, Richardson JD, Chowdhury EA, Koumanov F, Holman GD, Cooper S, Thompson D, Tsintzas K, Betts JA
The Journal of physiology 2018 Feb 15;596(4):609-622
The Journal of physiology 2018 Feb 15;596(4):609-622
Hypoxia Activates Src and Promotes Endocytosis Which Decreases MMP-2 Activity and Aggravates Renal Interstitial Fibrosis.
Cheng Z, Liu L, Wang Z, Cai Y, Xu Q, Chen P
International journal of molecular sciences 2018 Feb 15;19(2)
International journal of molecular sciences 2018 Feb 15;19(2)
hPMSC transplantation restoring ovarian function in premature ovarian failure mice is associated with change of Th17/Tc17 and Th17/Treg cell ratios through the PI3K/Akt signal pathway.
Yin N, Wang Y, Lu X, Liu R, Zhang L, Zhao W, Yuan W, Luo Q, Wu H, Luan X, Zhang H
Stem cell research & therapy 2018 Feb 14;9(1):37
Stem cell research & therapy 2018 Feb 14;9(1):37
Polycystin-2 is an essential ion channel subunit in the primary cilium of the renal collecting duct epithelium.
Liu X, Vien T, Duan J, Sheu SH, DeCaen PG, Clapham DE
eLife 2018 Feb 14;7
eLife 2018 Feb 14;7
MYL6B, a myosin light chain, promotes MDM2-mediated p53 degradation and drives HCC development.
Xie X, Wang X, Liao W, Fei R, Wu N, Cong X, Chen Q, Wei L, Wang Y, Chen H
Journal of experimental & clinical cancer research : CR 2018 Feb 13;37(1):28
Journal of experimental & clinical cancer research : CR 2018 Feb 13;37(1):28
MicroRNA-29a mitigation of toll-like receptor 2 and 4 signaling and alleviation of obstructive jaundice-induced fibrosis in mice.
Lin YC, Wang FS, Yang YL, Chuang YT, Huang YH
Biochemical and biophysical research communications 2018 Feb 12;496(3):880-886
Biochemical and biophysical research communications 2018 Feb 12;496(3):880-886
Ursolic Acid Attenuates High Glucose-Mediated Mesangial Cell Injury by Inhibiting the Phosphatidylinositol 3-Kinase/Akt/Mammalian Target of Rapamycin (PI3K/Akt/mTOR) Signaling Pathway.
Wang EM, Fan QL, Yue Y, Xu L
Medical science monitor : international medical journal of experimental and clinical research 2018 Feb 11;24:846-854
Medical science monitor : international medical journal of experimental and clinical research 2018 Feb 11;24:846-854
Fertility impairment with defective spermatogenesis and steroidogenesis in male zebrafish lacking androgen receptor.
Tang H, Chen Y, Wang L, Yin Y, Li G, Guo Y, Liu Y, Lin H, Cheng CHK, Liu X
Biology of reproduction 2018 Feb 1;98(2):227-238
Biology of reproduction 2018 Feb 1;98(2):227-238
Overcoming STC2 mediated drug resistance through drug and gene co-delivery by PHB-PDMAEMA cationic polyester in liver cancer cells.
Cheng H, Wu Z, Wu C, Wang X, Liow SS, Li Z, Wu YL
Materials science & engineering. C, Materials for biological applications 2018 Feb 1;83:210-217
Materials science & engineering. C, Materials for biological applications 2018 Feb 1;83:210-217
AF119895 regulates NXF3 expression to promote migration and invasion of hepatocellular carcinoma through an interaction with miR-6508-3p.
Zeng T, Wang D, Chen J, Chen K, Yu G, Chen Q, Liu Y, Yan S, Zhu L, Zhou H, Huang A, Tang H
Experimental cell research 2018 Feb 1;363(1):129-139
Experimental cell research 2018 Feb 1;363(1):129-139
Bone marrow mesenchymal stromal cells alleviate brain white matter injury via the enhanced proliferation of oligodendrocyte progenitor cells in focal cerebral ischemic rats.
Yu X, Wu H, Zhao Y, Guo Y, Chen Y, Dong P, Mu Q, Wang X, Wang X
Brain research 2018 Feb 1;1680:127-136
Brain research 2018 Feb 1;1680:127-136
Truncated SALL1 Impedes Primary Cilia Function in Townes-Brocks Syndrome.
Bozal-Basterra L, Martín-Ruíz I, Pirone L, Liang Y, Sigurðsson JO, Gonzalez-Santamarta M, Giordano I, Gabicagogeascoa E, de Luca A, Rodríguez JA, Wilkie AOM, Kohlhase J, Eastwood D, Yale C, Olsen JV, Rauchman M, Anderson KV, Sutherland JD, Barrio R
American journal of human genetics 2018 Feb 1;102(2):249-265
American journal of human genetics 2018 Feb 1;102(2):249-265
Novel synthetic 4-chlorobenzoyl berbamine inhibits c-Myc expression and induces apoptosis of diffuse large B cell lymphoma cells.
Zhang L, Tong J, He X, Liang Y, Zhu L, Xu R, Zhao X
Annals of hematology 2018 Dec;97(12):2353-2362
Annals of hematology 2018 Dec;97(12):2353-2362
Quercetin ameliorates pulmonary fibrosis by inhibiting SphK1/S1P signaling.
Zhang X, Cai Y, Zhang W, Chen X
Biochemistry and cell biology = Biochimie et biologie cellulaire 2018 Dec;96(6):742-751
Biochemistry and cell biology = Biochimie et biologie cellulaire 2018 Dec;96(6):742-751
Red nucleus interleukin-1β evokes tactile allodynia through activation of JAK/STAT3 and JNK signaling pathways.
Guo YJ, Li HN, Ding CP, Han SP, Wang JY
Journal of neuroscience research 2018 Dec;96(12):1847-1861
Journal of neuroscience research 2018 Dec;96(12):1847-1861
Apolipoprotein E Exerts a Whole-Brain Protective Property by Promoting M1? Microglia Quiescence After Experimental Subarachnoid Hemorrhage in Mice.
Pang J, Peng J, Matei N, Yang P, Kuai L, Wu Y, Chen L, Vitek MP, Li F, Sun X, Zhang JH, Jiang Y
Translational stroke research 2018 Dec;9(6):654-668
Translational stroke research 2018 Dec;9(6):654-668
IL-23-induced macrophage polarization and its pathological roles in mice with imiquimod-induced psoriasis.
Hou Y, Zhu L, Tian H, Sun HX, Wang R, Zhang L, Zhao Y
Protein & cell 2018 Dec;9(12):1027-1038
Protein & cell 2018 Dec;9(12):1027-1038
Autophagy participates in innate immune defense in lamprey.
Luo L, Lu J, Wang Q, Chen S, Xu A, Yuan S
Fish & shellfish immunology 2018 Dec;83:416-424
Fish & shellfish immunology 2018 Dec;83:416-424
Establishing a dual knock-out cell line by lentivirus based combined CRISPR/Cas9 and Loxp/Cre system.
Li Y, Zhang W, Zhao J, Li S, Shan L, Zhu J, Li Y, Zhu H, Mao Q, Xia H
Cytotechnology 2018 Dec;70(6):1595-1605
Cytotechnology 2018 Dec;70(6):1595-1605
Buffalo oocyte-secreted factors promote cumulus cells apoptosis and the rate of cGMP production but not steroidogenesis.
Moussa M, Li MQ, Zheng HY, Yang CY, Yan SF, Yu NQ, Huang JX, Shang JH
Reproduction in domestic animals = Zuchthygiene 2018 Dec;53(6):1523-1529
Reproduction in domestic animals = Zuchthygiene 2018 Dec;53(6):1523-1529
Prolyl hydroxylases positively regulated LPS-induced inflammation in human gingival fibroblasts via TLR4/MyD88-mediated AKT/NF-κB and MAPK pathways.
Shang L, Wang T, Tong D, Kang W, Liang Q, Ge S
Cell proliferation 2018 Dec;51(6):e12516
Cell proliferation 2018 Dec;51(6):e12516
Overexpression of CXCL2 inhibits cell proliferation and promotes apoptosis in hepatocellular carcinoma.
Ding J, Xu K, Zhang J, Lin B, Wang Y, Yin S, Xie H, Zhou L, Zheng S
BMB reports 2018 Dec;51(12):630-635
BMB reports 2018 Dec;51(12):630-635
PI3K/Akt signaling pathway and Hsp70 activate in hippocampus of rats with chronic manganese sulfate exposure.
Cheng H, Xia B, Su C, Chen K, Chen X, Chen P, Zou Y, Yang X
Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS) 2018 Dec;50:332-338
Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS) 2018 Dec;50:332-338
Klotho gene-modified BMSCs showed elevated antifibrotic effects by inhibiting the Wnt/β-catenin pathway in kidneys after acute injury.
Zhang F, Wan X, Cao YZ, Sun D, Cao CC
Cell biology international 2018 Dec;42(12):1670-1679
Cell biology international 2018 Dec;42(12):1670-1679
miR‑29a suppresses the growth and metastasis of hepatocellular carcinoma through IFITM3.
Liang Y, Li E, Min J, Gong C, Gao J, Ai J, Liao W, Wu L
Oncology reports 2018 Dec;40(6):3261-3272
Oncology reports 2018 Dec;40(6):3261-3272
The Scorpion Venom Peptide Smp76 Inhibits Viral Infection by Regulating Type-I Interferon Response.
Ji Z, Li F, Xia Z, Guo X, Gao M, Sun F, Cheng Y, Wu Y, Li W, Ali SA, Cao Z
Virologica Sinica 2018 Dec;33(6):545-556
Virologica Sinica 2018 Dec;33(6):545-556
Elevating ATP-binding cassette transporter G1 improves re-endothelialization function of endothelial progenitor cells via Lyn/Akt/eNOS in diabetic mice.
Shi Y, Lv X, Liu Y, Li B, Liu M, Yan M, Liu Y, Li Q, Zhang X, He S, Zhu M, He J, Zhu Y, Zhu Y, Ai D
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2018 Dec;32(12):6525-6536
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2018 Dec;32(12):6525-6536
Phenethyl isothiocyanate inhibits colorectal cancer stem cells by suppressing Wnt/β-catenin pathway.
Chen Y, Li Y, Wang XQ, Meng Y, Zhang Q, Zhu JY, Chen JQ, Cao WS, Wang XQ, Xie CF, Li XT, Geng SS, Wu JS, Zhong CY, Han HY
Phytotherapy research : PTR 2018 Dec;32(12):2447-2455
Phytotherapy research : PTR 2018 Dec;32(12):2447-2455
MicroRNA-146b-3p Promotes Cell Metastasis by Directly Targeting NF2 in Human Papillary Thyroid Cancer.
Yu C, Zhang L, Luo D, Yan F, Liu J, Shao S, Zhao L, Jin T, Zhao J, Gao L
Thyroid : official journal of the American Thyroid Association 2018 Dec;28(12):1627-1641
Thyroid : official journal of the American Thyroid Association 2018 Dec;28(12):1627-1641
Expression Analysis of ACSL5 and Wnt2B in Human Congenital Pulmonary Airway Malformations.
Qu Y, Liu D, Jia H, Zhou X
The Journal of surgical research 2018 Dec;232:128-136
The Journal of surgical research 2018 Dec;232:128-136
Effects of mdig on proliferation and apoptosis of lung cancer cells.
Xu X, Cao L, Zhang Y, Lian H, Sun Z, Cui Y
Oncology letters 2018 Dec;16(6):7146-7151
Oncology letters 2018 Dec;16(6):7146-7151
Influencing mechanism of magnolol on expression of BDNF and Bax in rats with cerebral ischemic stroke.
Liu Z, Xie J, Lin K, Qi L
Experimental and therapeutic medicine 2018 Dec;16(6):4423-4428
Experimental and therapeutic medicine 2018 Dec;16(6):4423-4428
Regulation of hippocampal long term depression by Neuroligin 1.
Dang R, Qi J, Liu A, Ren Q, Lv D, Han L, Zhou Z, Cao F, Xie W, Jia Z
Neuropharmacology 2018 Dec;143:205-216
Neuropharmacology 2018 Dec;143:205-216
Cathelicidin-WA attenuates LPS-induced inflammation and redox imbalance through activation of AMPK signaling.
Wu W, Wang S, Liu Q, Wang X, Shan T, Wang Y
Free radical biology & medicine 2018 Dec;129:338-353
Free radical biology & medicine 2018 Dec;129:338-353
Mechanism and prognostic value of indoleamine 2,3-dioxygenase 1 expressed in hepatocellular carcinoma.
Li S, Han X, Lyu N, Xie Q, Deng H, Mu L, Pan T, Huang X, Wang X, Shi Y, Zhao M
Cancer science 2018 Dec;109(12):3726-3736
Cancer science 2018 Dec;109(12):3726-3736
Transcription factor 7-like 2 controls matrix degradation through nuclear factor κB signaling and is repressed by microRNA-155 in nucleus pulposus cells.
Sun J, Hong J, Sun S, Wang X, Peng Y, Zhou J, Huang Y, Li S, Chen W, Li C, Xu K, Ye W
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Dec;108:646-655
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Dec;108:646-655
PNMA1, regulated by miR-33a-5p, promotes proliferation and EMT in hepatocellular carcinoma by activating the Wnt/β-catenin pathway.
Liu P, Chen B, Gu Y, Liu Q
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Dec;108:492-499
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Dec;108:492-499
Dynasore-induced potent ubiquitylation of the exon 19 deletion mutant of epidermal growth factor receptor suppresses cell growth and migration in non-small cell lung cancer.
Wang T, Wang D, Zhang Y, Zhang J, Sun X, Wu Y, Wang S, Zhang Y, Xu L, Kong Q, Gao Y, Wu Y, Liu F, Liu S, Zhang Y, Lei T, Liu H
The international journal of biochemistry & cell biology 2018 Dec;105:1-12
The international journal of biochemistry & cell biology 2018 Dec;105:1-12
A novel pathway of LPS uptake through syndecan-1 leading to pyroptotic cell death.
Yokoyama S, Cai Y, Murata M, Tomita T, Yoneda M, Xu L, Pilon AL, Cachau RE, Kimura S
eLife 2018 Dec 7;7
eLife 2018 Dec 7;7
A Simplified System to Express Circularized Inhibitors of miRNA for Stable and Potent Suppression of miRNA Functions.
Shu Y, Wu K, Zeng Z, Huang S, Ji X, Yuan C, Zhang L, Liu W, Huang B, Feng Y, Zhang B, Dai Z, Shen Y, Luo W, Wang X, Liu B, Lei Y, Ye Z, Zhao L, Cao D, Yang L, Chen X, Luu HH, Reid RR, Wolf JM, Lee MJ, He TC
Molecular therapy. Nucleic acids 2018 Dec 7;13:556-567
Molecular therapy. Nucleic acids 2018 Dec 7;13:556-567
NR2C2-uORF targeting UCA1-miR-627-5p-NR2C2 feedback loop to regulate the malignant behaviors of glioma cells.
Fan Z, Zheng J, Xue Y, Liu X, Wang D, Yang C, Ma J, Liu L, Ruan X, Wang Z, Liu Y
Cell death & disease 2018 Dec 5;9(12):1165
Cell death & disease 2018 Dec 5;9(12):1165
MAN1B1 is associated with poor prognosis and modulates proliferation and apoptosis in bladder cancer.
Wang HF, Wu JH, Gai JW, Yang SQ, Ma QT, Ma HS, Feng Q
Gene 2018 Dec 30;679:314-319
Gene 2018 Dec 30;679:314-319
LINC00052/miR-101-3p axis inhibits cell proliferation and metastasis by targeting SOX9 in hepatocellular carcinoma.
Yan S, Shan X, Chen K, Liu Y, Yu G, Chen Q, Zeng T, Zhu L, Dang H, Chen F, Ling J, Huang A, Tang H
Gene 2018 Dec 30;679:138-149
Gene 2018 Dec 30;679:138-149
Systematic analysis of synergistic proteome modulations in a drug combination of cisplatin and MLN4924.
Megger DA, Abou-Eid S, Zülch B, Sitek B
Molecular omics 2018 Dec 3;14(6):450-457
Molecular omics 2018 Dec 3;14(6):450-457
4'-hydroxywogonin inhibits colorectal cancer angiogenesis by disrupting PI3K/AKT signaling.
Sun D, Zhang F, Qian J, Shen W, Fan H, Tan J, Li L, Xu C, Yang Y, Cheng H
Chemico-biological interactions 2018 Dec 25;296:26-33
Chemico-biological interactions 2018 Dec 25;296:26-33
Anti-tumoral potential of MDA19 in human osteosarcoma via suppressing PI3K/Akt/mTOR signaling pathway.
Liu B, Xu L, Dai EN, Tian JX, Li JM
Bioscience reports 2018 Dec 21;38(6)
Bioscience reports 2018 Dec 21;38(6)
Jian-Pi-Yi-Shen Formula ameliorates chronic kidney disease: involvement of mitochondrial quality control network.
Liu X, Chen J, Liu X, Wang D, Zheng P, Qi A, Yi T, Li S
BMC complementary and alternative medicine 2018 Dec 20;18(1):340
BMC complementary and alternative medicine 2018 Dec 20;18(1):340
Gli2 modulates cell cycle re-entry through autophagy-mediated regulation of the length of primary cilia.
Hsiao CJ, Chang CH, Ibrahim RB, Lin IH, Wang CH, Wang WJ, Tsai JW
Journal of cell science 2018 Dec 17;131(24)
Journal of cell science 2018 Dec 17;131(24)
CVB3 Nonstructural 2A Protein Modulates SREBP1a Signaling via the MEK/ERK Pathway.
Wang L, Xie W, Zhang L, Li D, Yu H, Xiong J, Peng J, Qiu J, Sheng H, He X, Zhang K
Journal of virology 2018 Dec 15;92(24)
Journal of virology 2018 Dec 15;92(24)
Perigestational exposure to low doses of PBDE-47 induces excessive ER stress, defective autophagy and the resultant apoptosis contributing to maternal thyroid toxicity.
Li P, Liu L, Zhou G, Tian Z, Luo C, Xia T, Chen J, Niu Q, Dong L, Zhao Q, Wang A, Zhang S
The Science of the total environment 2018 Dec 15;645:363-371
The Science of the total environment 2018 Dec 15;645:363-371
Dexmedetomidine alleviates cerebral ischemia-reperfusion injury by inhibiting endoplasmic reticulum stress dependent apoptosis through the PERK-CHOP-Caspase-11 pathway.
Liu C, Fu Q, Mu R, Wang F, Zhou C, Zhang L, Yu B, Zhang Y, Fang T, Tian F
Brain research 2018 Dec 15;1701:246-254
Brain research 2018 Dec 15;1701:246-254
Metformin regulates atrial SK2 and SK3 expression through inhibiting the PKC/ERK signaling pathway in type 2 diabetic rats.
Liu CH, Hua N, Fu X, Pan YL, Li B, Li XD
BMC cardiovascular disorders 2018 Dec 13;18(1):236
BMC cardiovascular disorders 2018 Dec 13;18(1):236
Epigenetic suppression of E-cadherin expression by Snail2 during the metastasis of colorectal cancer.
Hu Y, Dai M, Zheng Y, Wu J, Yu B, Zhang H, Kong W, Wu H, Yu X
Clinical epigenetics 2018 Dec 12;10(1):154
Clinical epigenetics 2018 Dec 12;10(1):154
Co-targeting PLK1 and mTOR induces synergistic inhibitory effects against esophageal squamous cell carcinoma.
Liu TT, Yang KX, Yu J, Cao YY, Ren JS, Hao JJ, Pan BQ, Ma S, Yang LY, Cai Y, Wang MR, Zhang Y
Journal of molecular medicine (Berlin, Germany) 2018 Aug;96(8):807-817
Journal of molecular medicine (Berlin, Germany) 2018 Aug;96(8):807-817
miR-128-3p regulates 3T3-L1 adipogenesis and lipolysis by targeting Pparg and Sertad2.
Chen C, Deng Y, Hu X, Ren H, Zhu J, Fu S, Xie J, Peng Y
Journal of physiology and biochemistry 2018 Aug;74(3):381-393
Journal of physiology and biochemistry 2018 Aug;74(3):381-393
Radiosensitizing effects of miR-18a-5p on lung cancer stem-like cells via downregulating both ATM and HIF-1α.
Chen X, Wu L, Li D, Xu Y, Zhang L, Niu K, Kong R, Gu J, Xu Z, Chen Z, Sun J
Cancer medicine 2018 Aug;7(8):3834-3847
Cancer medicine 2018 Aug;7(8):3834-3847
NRG1 regulates redox homeostasis via NRF2 in papillary thyroid cancer.
Zhang TT, Qu N, Sun GH, Zhang L, Wang YJ, Mu XM, Wei WJ, Wang YL, Wang Y, Ji QH, Zhu YX, Shi RL
International journal of oncology 2018 Aug;53(2):685-693
International journal of oncology 2018 Aug;53(2):685-693
Overexpression of PRDM13 inhibits glioma cells via Rho and GTP enzyme activation protein.
Zhang L, Cao H, He T, Yang J, Tao H, Wang Y, Hu Q
International journal of molecular medicine 2018 Aug;42(2):966-974
International journal of molecular medicine 2018 Aug;42(2):966-974
Overexpression of FOXQ1 enhances anti-senescence and migration effects of human umbilical cord mesenchymal stem cells in vitro and in vivo.
Zhang T, Wang P, Liu Y, Zhou J, Shi Z, Cheng K, Huang T, Wang X, Yang GL, Yang B, Ma S, Guan F
Cell and tissue research 2018 Aug;373(2):379-393
Cell and tissue research 2018 Aug;373(2):379-393
Scribble influences cyst formation in autosomal-dominant polycystic kidney disease by regulating Hippo signaling pathway.
Xu D, Lv J, He L, Fu L, Hu R, Cao Y, Mei C
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2018 Aug;32(8):4394-4407
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2018 Aug;32(8):4394-4407
Increased Expression of NDRG3 in Mouse Uterus During Embryo Implantation and in Mouse Endometrial Stromal Cells During In Vitro Decidualization.
Yang Q, Zhang X, Shi Y, He YP, Sun ZG, Shi HJ, Wang J
Reproductive sciences (Thousand Oaks, Calif.) 2018 Aug;25(8):1197-1207
Reproductive sciences (Thousand Oaks, Calif.) 2018 Aug;25(8):1197-1207
LncRNA BDNF-AS inhibits proliferation, migration, invasion and EMT in oesophageal cancer cells by targeting miR-214.
Zhao H, Diao C, Wang X, Xie Y, Liu Y, Gao X, Han J, Li S
Journal of cellular and molecular medicine 2018 Aug;22(8):3729-3739
Journal of cellular and molecular medicine 2018 Aug;22(8):3729-3739
Revealing A-Raf functions through its interactome.
Zhang XY, Guo H, Han B, Zhang XM, Huang Y, Yang Y, Liu Y, Guo XX, Hao Q, An S, Xu TR
Biochimica et biophysica acta. Proteins and proteomics 2018 Aug;1866(8):849-856
Biochimica et biophysica acta. Proteins and proteomics 2018 Aug;1866(8):849-856
miR-205-5p inhibits cell migration and invasion in prostatic carcinoma by targeting ZEB1.
Li L, Li S
Oncology letters 2018 Aug;16(2):1715-1721
Oncology letters 2018 Aug;16(2):1715-1721
Peri-ovarian adipose tissue contributes to intraovarian control during folliculogenesis in mice.
Yang L, Chen L, Lu X, Tan A, Chen Y, Li Y, Peng X, Yuan S, Cai D, Yu Y
Reproduction (Cambridge, England) 2018 Aug;156(2):133-144
Reproduction (Cambridge, England) 2018 Aug;156(2):133-144
MicroRNA-135a inhibits cardiac fibrosis induced by isoproterenol via TRPM7 channel.
Wu Y, Liu Y, Pan Y, Lu C, Xu H, Wang X, Liu T, Feng K, Tang Y
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Aug;104:252-260
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Aug;104:252-260
ITGBL1 promotes migration, invasion and predicts a poor prognosis in colorectal cancer.
Qiu X, Feng JR, Qiu J, Liu L, Xie Y, Zhang YP, Liu J, Zhao Q
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Aug;104:172-180
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Aug;104:172-180
Warfarin and vitamin K epoxide reductase: a molecular accounting for observed inhibition.
Wu S, Chen X, Jin DY, Stafford DW, Pedersen LG, Tie JK
Blood 2018 Aug 9;132(6):647-657
Blood 2018 Aug 9;132(6):647-657
Anillin is required for tumor growth and regulated by miR-15a/miR-16-1 in HBV-related hepatocellular carcinoma.
Lian YF, Huang YL, Wang JL, Deng MH, Xia TL, Zeng MS, Chen MS, Wang HB, Huang YH
Aging 2018 Aug 9;10(8):1884-1901
Aging 2018 Aug 9;10(8):1884-1901
HMGB1 knockdown increases MM cell vulnerability by regulating autophagy and DNA damage repair.
Guo X, He D, Zhang E, Chen J, Chen Q, Li Y, Yang L, Yang Y, Zhao Y, Wang G, He J, Cai Z
Journal of experimental & clinical cancer research : CR 2018 Aug 29;37(1):205
Journal of experimental & clinical cancer research : CR 2018 Aug 29;37(1):205
Ubiquitin-conjugating enzyme UBE2J1 negatively modulates interferon pathway and promotes RNA virus infection.
Feng T, Deng L, Lu X, Pan W, Wu Q, Dai J
Virology journal 2018 Aug 29;15(1):132
Virology journal 2018 Aug 29;15(1):132
MALAT1-miR663a negative feedback loop in colon cancer cell functions through direct miRNA-lncRNA binding.
Tian W, Du Y, Ma Y, Gu L, Zhou J, Deng D
Cell death & disease 2018 Aug 28;9(9):857
Cell death & disease 2018 Aug 28;9(9):857
Hepatocyte Wnts Are Dispensable During Diethylnitrosamine and Carbon Tetrachloride-Induced Injury and Hepatocellular Cancer.
Preziosi M, Poddar M, Singh S, Monga SP
Gene expression 2018 Aug 22;18(3):209-219
Gene expression 2018 Aug 22;18(3):209-219
Cold atmospheric plasma conveys selectivity on triple negative breast cancer cells both in vitro and in vivo.
Xiang L, Xu X, Zhang S, Cai D, Dai X
Free radical biology & medicine 2018 Aug 20;124:205-213
Free radical biology & medicine 2018 Aug 20;124:205-213
Increased Expression of CD81 in Breast Cancer Tissue is Associated with Reduced Patient Prognosis and Increased Cell Migration and Proliferation in MDA-MB-231 and MDA-MB-435S Human Breast Cancer Cell Lines In Vitro.
Zhang N, Zuo L, Zheng H, Li G, Hu X
Medical science monitor : international medical journal of experimental and clinical research 2018 Aug 17;24:5739-5747
Medical science monitor : international medical journal of experimental and clinical research 2018 Aug 17;24:5739-5747
Motoneuron Wnts regulate neuromuscular junction development.
Shen C, Li L, Zhao K, Bai L, Wang A, Shu X, Xiao Y, Zhang J, Zhang K, Hui T, Chen W, Zhang B, Hsu W, Xiong WC, Mei L
eLife 2018 Aug 16;7
eLife 2018 Aug 16;7
Inhibition of mTORC1 signaling protects kidney from irradiation-induced toxicity via accelerating recovery of renal stem-like cells.
Shao L, Yang W, Xu R, Zhu S, Huang Y, Li H, Wu X, Yue M, Xiong X, Chen X, Kuang B, Fan G, Zhu Q, Zeng H
Stem cell research & therapy 2018 Aug 14;9(1):219
Stem cell research & therapy 2018 Aug 14;9(1):219
Transactive Response DNA-Binding Protein 43 Abnormalities after Traumatic Brain Injury.
Tan XL, Sun M, Brady RD, Liu S, Llanos R, Cheung S, Wright DK, Casillas-Espinosa PM, Sashindranath M, O'Brien TJ, McDonald SJ, Turner BJ, Shultz SR
Journal of neurotrauma 2018 Aug 10;
Journal of neurotrauma 2018 Aug 10;
Antifertility effectiveness of a novel copper-containing intrauterine device material and its influence on the endometrial environment in rats.
Hu S, Wang Y, Ke D, Zhou F, Cheng G, Xia W, Zhu C
Materials science & engineering. C, Materials for biological applications 2018 Aug 1;89:444-455
Materials science & engineering. C, Materials for biological applications 2018 Aug 1;89:444-455
Lanthanum chloride reduces lactate production in primary culture rat cortical astrocytes and suppresses primary co-culture rat cortical astrocyte-neuron lactate transport.
Sun Y, Yang J, Hu X, Gao X, Li Y, Yu M, Liu S, Lu X, Jin C, Wu S, Cai Y
Archives of toxicology 2018 Apr;92(4):1407-1419
Archives of toxicology 2018 Apr;92(4):1407-1419
Interleukin-17A participates in podocyte injury by inducing IL-1β secretion through ROS-NLRP3 inflammasome-caspase-1 pathway.
Yan J, Li Y, Yang H, Zhang L, Yang B, Wang M, Li Q
Scandinavian journal of immunology 2018 Apr;87(4):e12645
Scandinavian journal of immunology 2018 Apr;87(4):e12645
PARP inhibitor olaparib sensitizes cholangiocarcinoma cells to radiation.
Mao Y, Huang X, Shuang Z, Lin G, Wang J, Duan F, Chen J, Li S
Cancer medicine 2018 Apr;7(4):1285-1296
Cancer medicine 2018 Apr;7(4):1285-1296
Gemin5 plays a role in unassembled-U1 snRNA disposal in SMN-deficient cells.
Jiang D, Zou X, Zhang C, Chen J, Li Z, Wang Y, Deng Z, Wang L, Chen S
FEBS letters 2018 Apr;592(8):1400-1411
FEBS letters 2018 Apr;592(8):1400-1411
MDM2 Degrades Deacetylated Nucleolin Through Ubiquitination to Promote Glioma Stem-Like Cell Enrichment for Chemotherapeutic Resistance.
Ko CY, Lin CH, Chuang JY, Chang WC, Hsu TI
Molecular neurobiology 2018 Apr;55(4):3211-3223
Molecular neurobiology 2018 Apr;55(4):3211-3223
Rolipram Attenuates Early Brain Injury Following Experimental Subarachnoid Hemorrhage in Rats: Possibly via Regulating the SIRT1/NF-κB Pathway.
Peng Y, Jin J, Fan L, Xu H, He P, Li J, Chen T, Ruan W, Chen G
Neurochemical research 2018 Apr;43(4):785-795
Neurochemical research 2018 Apr;43(4):785-795
miR‑21‑5p confers doxorubicin resistance in gastric cancer cells by targeting PTEN and TIMP3.
Chen J, Zhou C, Li J, Xiang X, Zhang L, Deng J, Xiong J
International journal of molecular medicine 2018 Apr;41(4):1855-1866
International journal of molecular medicine 2018 Apr;41(4):1855-1866
MiR-151a is involved in the pathogenesis of atopic dermatitis by regulating interleukin-12 receptor β2.
Chen XF, Zhang LJ, Zhang J, Dou X, Shao Y, Jia XJ, Zhang W, Yu B
Experimental dermatology 2018 Apr;27(4):427-432
Experimental dermatology 2018 Apr;27(4):427-432
Targeting P-glycoprotein and SORCIN: Dihydromyricetin strengthens anti-proliferative efficiency of adriamycin via MAPK/ERK and Ca(2+) -mediated apoptosis pathways in MCF-7/ADR and K562/ADR.
Sun Y, Wang C, Meng Q, Liu Z, Huo X, Sun P, Sun H, Ma X, Peng J, Liu K
Journal of cellular physiology 2018 Apr;233(4):3066-3079
Journal of cellular physiology 2018 Apr;233(4):3066-3079
TXNDC5 contributes to rheumatoid arthritis by down-regulating IGFBP1 expression.
Li J, Xu B, Wu C, Yan X, Zhang L, Chang X
Clinical and experimental immunology 2018 Apr;192(1):82-94
Clinical and experimental immunology 2018 Apr;192(1):82-94
Phenformin inhibits cell proliferation and induces cell apoptosis and autophagy in cholangiocarcinoma.
Hu S, Ouyang Q, Cheng Q, Wang J, Feng F, Qiao L, Gan W, Shi Y, Wu D, Jiang X
Molecular medicine reports 2018 Apr;17(4):6028-6032
Molecular medicine reports 2018 Apr;17(4):6028-6032
Zoledronic acid sensitizes breast cancer cells to fulvestrant via ERK/HIF-1 pathway inhibition in vivo.
Jia X, Cheng J, Shen Z, Shao Z, Liu G
Molecular medicine reports 2018 Apr;17(4):5470-5476
Molecular medicine reports 2018 Apr;17(4):5470-5476
Effect of TLR4/MyD88 signaling pathway on sepsis-associated acute respiratory distress syndrome in rats, via regulation of macrophage activation and inflammatory response.
Zhou S, Wang G, Zhang W
Experimental and therapeutic medicine 2018 Apr;15(4):3376-3384
Experimental and therapeutic medicine 2018 Apr;15(4):3376-3384
Screening the expression characteristics of several miRNAs in G93A-SOD1 transgenic mouse: altered expression of miRNA-124 is associated with astrocyte differentiation by targeting Sox2 and Sox9.
Zhou F, Zhang C, Guan Y, Chen Y, Lu Q, Jie L, Gao H, Du H, Zhang H, Liu Y, Wang X
Journal of neurochemistry 2018 Apr;145(1):51-67
Journal of neurochemistry 2018 Apr;145(1):51-67
TSR2 Induces laryngeal cancer cell apoptosis through inhibiting NF-κB signaling pathway.
He HJ, Bing H, Liu G
The Laryngoscope 2018 Apr;128(4):E130-E134
The Laryngoscope 2018 Apr;128(4):E130-E134
Icariside II attenuates myocardial fibrosis by inhibiting nuclear factor-κB and the TGF-β1/Smad2 signalling pathway in spontaneously hypertensive rats.
Fu S, Li YL, Wu YT, Yue Y, Qian ZQ, Yang DL
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Apr;100:64-71
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Apr;100:64-71
Apocynum venetum leaf extract reverses depressive-like behaviors in chronically stressed rats by inhibiting oxidative stress and apoptosis.
Li X, Wu T, Yu Z, Li T, Zhang J, Zhang Z, Cai M, Zhang W, Xiang J, Cai D
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Apr;100:394-406
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Apr;100:394-406
Ezrin/NF-κB Pathway Regulates EGF-induced Epithelial-Mesenchymal Transition (EMT), Metastasis, and Progression of Osteosarcoma.
Liu P, Yang P, Zhang Z, Liu M, Hu S
Medical science monitor : international medical journal of experimental and clinical research 2018 Apr 9;24:2098-2108
Medical science monitor : international medical journal of experimental and clinical research 2018 Apr 9;24:2098-2108
Protective effect of methylallyl sulfone in the development of cigarette smoke extract-induced apoptosis in rats and HFL-1 cells.
Li A, Liu Y, Zhu X, Sun X, Feng X, Li D, Zhang J, Zhu M, Zhao Z
Biochemical and biophysical research communications 2018 Apr 6;498(3):627-632
Biochemical and biophysical research communications 2018 Apr 6;498(3):627-632
R-spondin3-LGR4 signaling protects hepatocytes against DMOG-induced hypoxia/reoxygenation injury through activating β-catenin.
Liu S, Yin Y, Yu R, Li Y, Zhang W
Biochemical and biophysical research communications 2018 Apr 30;499(1):59-65
Biochemical and biophysical research communications 2018 Apr 30;499(1):59-65
Down-regulation of miR-10a-5p promotes proliferation and restricts apoptosis via targeting T-box transcription factor 5 in inflamed synoviocytes.
Hussain N, Zhu W, Jiang C, Xu J, Geng M, Wu X, Hussain S, Wang B, Rajoka MSR, Li Y, Tian J, Meng L, Lu S
Bioscience reports 2018 Apr 27;38(2)
Bioscience reports 2018 Apr 27;38(2)
Characterization of RUNX1T1, an Adipogenesis Regulator in Ovine Preadipocyte Differentiation.
Deng K, Ren C, Liu Z, Gao X, Fan Y, Zhang G, Zhang Y, Ma ES, Wang F, You P
International journal of molecular sciences 2018 Apr 26;19(5)
International journal of molecular sciences 2018 Apr 26;19(5)
Ehrlichia chaffeensis TRP75 Interacts with Host Cell Targets Involved in Homeostasis, Cytoskeleton Organization, and Apoptosis Regulation To Promote Infection.
Luo T, Mitra S, McBride JW
mSphere 2018 Apr 25;3(2)
mSphere 2018 Apr 25;3(2)
The LINC01138 drives malignancies via activating arginine methyltransferase 5 in hepatocellular carcinoma.
Li Z, Zhang J, Liu X, Li S, Wang Q, Di Chen, Hu Z, Yu T, Ding J, Li J, Yao M, Fan J, Huang S, Gao Q, Zhao Y, He X
Nature communications 2018 Apr 20;9(1):1572
Nature communications 2018 Apr 20;9(1):1572
RUVBL1, a novel C-RAF-binding protein, activates the RAF/MEK/ERK pathway to promote lung cancer tumorigenesis.
Guo H, Zhang XY, Peng J, Huang Y, Yang Y, Liu Y, Guo XX, Hao Q, An S, Xu TR
Biochemical and biophysical research communications 2018 Apr 15;498(4):932-939
Biochemical and biophysical research communications 2018 Apr 15;498(4):932-939
RGC32 Promotes Bleomycin-Induced Systemic Sclerosis in a Murine Disease Model by Modulating Classically Activated Macrophage Function.
Sun C, Chen SY
Journal of immunology (Baltimore, Md. : 1950) 2018 Apr 15;200(8):2777-2785
Journal of immunology (Baltimore, Md. : 1950) 2018 Apr 15;200(8):2777-2785
Vitamin A pretreatment protects NO-induced bovine mammary epithelial cells from oxidative stress by modulating Nrf2 and NF-κB signaling pathways.
Shi HY, Yan SM, Guo YM, Zhang BQ, Guo XY, Shi BL
Journal of animal science 2018 Apr 14;96(4):1305-1316
Journal of animal science 2018 Apr 14;96(4):1305-1316
gga-miR-451 Negatively Regulates Mycoplasma gallisepticum (HS Strain)-Induced Inflammatory Cytokine Production via Targeting YWHAZ.
Zhao Y, Zhang K, Zou M, Sun Y, Peng X
International journal of molecular sciences 2018 Apr 13;19(4)
International journal of molecular sciences 2018 Apr 13;19(4)
Lysophosphatidic Acid Induces ECM Production via Activation of the Mechanosensitive YAP/TAZ Transcriptional Pathway in Trabecular Meshwork Cells.
Ho LTY, Skiba N, Ullmer C, Rao PV
Investigative ophthalmology & visual science 2018 Apr 1;59(5):1969-1984
Investigative ophthalmology & visual science 2018 Apr 1;59(5):1969-1984
Caspase Inhibition Reduces Hepatic Tissue Factor-Driven Coagulation In Vitro and In Vivo.
Kopec AK, Spada AP, Contreras PC, Mackman N, Luyendyk JP
Toxicological sciences : an official journal of the Society of Toxicology 2018 Apr 1;162(2):396-405
Toxicological sciences : an official journal of the Society of Toxicology 2018 Apr 1;162(2):396-405
IncRNA H19 promotes tongue squamous cell carcinoma progression through β-catenin/GSK3β/EMT signaling via association with EZH2.
Zhang DM, Lin ZY, Yang ZH, Wang YY, Wan D, Zhong JL, Zhuang PL, Huang ZQ, Zhou B, Chen WL
American journal of translational research 2017;9(7):3474-3486
American journal of translational research 2017;9(7):3474-3486
RIZ1 negatively regulates ubiquitin-conjugating enzyme E2C/UbcH10 via targeting c-Myc in meningioma.
Cai Z, Zou Y, Hu H, Lu C, Sun W, Jiang L, Hu G
American journal of translational research 2017;9(5):2645-2655
American journal of translational research 2017;9(5):2645-2655
Down-regulation of miR-125a-5p is associated with salivary adenoid cystic carcinoma progression via targeting p38/JNK/ERK signal pathway.
Liang Y, Ye J, Jiao J, Zhang J, Lu Y, Zhang L, Wan D, Duan L, Wu Y, Zhang B
American journal of translational research 2017;9(3):1101-1113
American journal of translational research 2017;9(3):1101-1113
Upregulation of TSPAN12 is associated with the colorectal cancer growth and metastasis.
Liu J, Chen C, Li G, Chen D, Zhou Q
American journal of translational research 2017;9(2):812-822
American journal of translational research 2017;9(2):812-822
DDX3 binding with CK1ε was closely related to motor neuron degeneration of ALS by affecting neurite outgrowth.
Chen Y, Wang Q, Wang Q, Liu H, Zhou F, Zhang Y, Yuan M, Zhao C, Guan Y, Wang X
American journal of translational research 2017;9(10):4627-4639
American journal of translational research 2017;9(10):4627-4639
Levodopa/Benserazide Loaded Microspheres Alleviate L-dopa Induced Dyskinesia through Preventing the Over-Expression of D1R/Shp-2/ERK1/2 Signaling Pathway in a Rat Model of Parkinson's Disease.
Wan Y, Wu N, Song L, Wang X, Liu Z, Yuan W, Gan J
Frontiers in aging neuroscience 2017;9:331
Frontiers in aging neuroscience 2017;9:331
The role of the chemokine receptor XCR1 in breast cancer cells.
Yang XL, Qi LG, Lin FJ, Ou ZL
Breast cancer (Dove Medical Press) 2017;9:227-236
Breast cancer (Dove Medical Press) 2017;9:227-236
The Frequency-Dependent Aerobic Exercise Effects of Hypothalamic GABAergic Expression and Cardiovascular Functions in Aged Rats.
Li Y, Zhao Z, Cai J, Gu B, Lv Y, Zhao L
Frontiers in aging neuroscience 2017;9:212
Frontiers in aging neuroscience 2017;9:212
Methylation of ZNF331 is an independent prognostic marker of colorectal cancer and promotes colorectal cancer growth.
Wang Y, He T, Herman JG, Linghu E, Yang Y, Fuks F, Zhou F, Song L, Guo M
Clinical epigenetics 2017;9:115
Clinical epigenetics 2017;9:115
Downregulation of Mitochondrial Single Stranded DNA Binding Protein (SSBP1) Induces Mitochondrial Dysfunction and Increases the Radiosensitivity in Non-Small Cell Lung Cancer Cells.
Wang Y, Hu L, Zhang X, Zhao H, Xu H, Wei Y, Jiang H, Xie C, Zhou Y, Zhou F
Journal of Cancer 2017;8(8):1400-1409
Journal of Cancer 2017;8(8):1400-1409
HES1 Promotes Colorectal Cancer Cell Resistance To 5-Fu by Inducing Of EMT and ABC Transporter Proteins.
Sun L, Ke J, He Z, Chen Z, Huang Q, Ai W, Wang G, Wei Y, Zou X, Zhang S, Lan P, Hong C
Journal of Cancer 2017;8(14):2802-2808
Journal of Cancer 2017;8(14):2802-2808
CDC27 Induces Metastasis and Invasion in Colorectal Cancer via the Promotion of Epithelial-To-Mesenchymal Transition.
Qiu L, Tan X, Lin J, Liu RY, Chen S, Geng R, Wu J, Huang W
Journal of Cancer 2017;8(13):2626-2635
Journal of Cancer 2017;8(13):2626-2635
Interferon-α Promotes the Expression of Cancer Stem Cell Markers in Oral Squamous Cell Carcinoma.
Ma H, Jin S, Yang W, Tian Z, Liu S, Wang Y, Zhou G, Zhao M, Gvetadze S, Zhang Z, Hu J
Journal of Cancer 2017;8(12):2384-2393
Journal of Cancer 2017;8(12):2384-2393
In vitro Cytotoxic Activities of the Oral Platinum(IV) Prodrug Oxoplatin and HSP90 Inhibitor Ganetespib against a Panel of Gastric Cancer Cell Lines.
Klameth L, Rath B, Hamilton G
Journal of Cancer 2017;8(10):1733-1743
Journal of Cancer 2017;8(10):1733-1743
Carnosic Acid Alleviates BDL-Induced Liver Fibrosis through miR-29b-3p-Mediated Inhibition of the High-Mobility Group Box 1/Toll-Like Receptor 4 Signaling Pathway in Rats.
Zhang S, Wang Z, Zhu J, Xu T, Zhao Y, Zhao H, Tang F, Li Z, Zhou J, Gao D, Tian X, Yao J
Frontiers in pharmacology 2017;8:976
Frontiers in pharmacology 2017;8:976
Antidiabetic Effect of Tibetan Medicine Tang-Kang-Fu-San in db/db Mice via Activation of PI3K/Akt and AMPK Pathways.
Duan B, Zhao Z, Liao W, Xiong H, Liu S, Yin L, Gao T, Mei Z
Frontiers in pharmacology 2017;8:535
Frontiers in pharmacology 2017;8:535
Fentanyl Promotes Breast Cancer Cell Stemness and Epithelial-Mesenchymal Transition by Upregulating α1, 6-Fucosylation via Wnt/β-Catenin Signaling Pathway.
Yang HF, Yu M, Jin HD, Yao JQ, Lu ZL, Yabasin IB, Yan Q, Wen QP
Frontiers in physiology 2017;8:510
Frontiers in physiology 2017;8:510
Lactobacillus rhamnosus GG Affects Microbiota and Suppresses Autophagy in the Intestines of Pigs Challenged with Salmonella Infantis.
Zhang W, Zhu YH, Yang GY, Liu X, Xia B, Hu X, Su JH, Wang JF
Frontiers in microbiology 2017;8:2705
Frontiers in microbiology 2017;8:2705
Screening and Identification of the Host Proteins Interacting with Toxoplasma gondii Rhoptry Protein ROP16.
Pan M, Zhou Y, Wang Y, Li L, Song Y, Hou L, Zhao J
Frontiers in microbiology 2017;8:2408
Frontiers in microbiology 2017;8:2408
Lab-Attenuated Rabies Virus Causes Abortive Infection and Induces Cytokine Expression in Astrocytes by Activating Mitochondrial Antiviral-Signaling Protein Signaling Pathway.
Tian B, Zhou M, Yang Y, Yu L, Luo Z, Tian D, Wang K, Cui M, Chen H, Fu ZF, Zhao L
Frontiers in immunology 2017;8:2011
Frontiers in immunology 2017;8:2011
Protective Effects of Dioscin against Lipopolysaccharide-Induced Acute Lung Injury through Inhibition of Oxidative Stress and Inflammation.
Yao H, Sun Y, Song S, Qi Y, Tao X, Xu L, Yin L, Han X, Xu Y, Li H, Sun H, Peng J
Frontiers in pharmacology 2017;8:120
Frontiers in pharmacology 2017;8:120
LncRNA ZFAS1 promotes growth and metastasis by regulating BMI1 and ZEB2 in osteosarcoma.
Liu G, Wang L, Han H, Li Y, Lu S, Li T, Cheng C
American journal of cancer research 2017;7(7):1450-1462
American journal of cancer research 2017;7(7):1450-1462
Obatoclax and LY3009120 Efficiently Overcome Vemurafenib Resistance in Differentiated Thyroid Cancer.
Wei WJ, Sun ZK, Shen CT, Song HJ, Zhang XY, Qiu ZL, Luo QY
Theranostics 2017;7(4):987-1001
Theranostics 2017;7(4):987-1001
miR-381-3p suppresses the proliferation of oral squamous cell carcinoma cells by directly targeting FGFR2.
Yang X, Ruan H, Hu X, Cao A, Song L
American journal of cancer research 2017;7(4):913-922
American journal of cancer research 2017;7(4):913-922
NRSN2 promotes osteosarcoma cell proliferation and growth through PI3K/Akt/MTOR and Wnt/β-catenin signaling.
Keremu A, Maimaiti X, Aimaiti A, Yushan M, Alike Y, Yilihamu Y, Yusufu A
American journal of cancer research 2017;7(3):565-573
American journal of cancer research 2017;7(3):565-573
Angiopoietin-like protein 2 facilitates non-small cell lung cancer progression by promoting the polarization of M2 tumor-associated macrophages.
Wei X, Nie S, Liu H, Sun J, Liu J, Li J, Li S, Wang S, Han S, Wang J, Sun Y
American journal of cancer research 2017;7(11):2220-2233
American journal of cancer research 2017;7(11):2220-2233
Targeting NF-κB/AP-2β signaling to enhance antitumor activity of cisplatin by melatonin in hepatocellular carcinoma cells.
Hao J, Li Z, Zhang C, Yu W, Tang Z, Li Y, Feng X, Gao Y, Liu Q, Huang W, Guo W, Deng W
American journal of cancer research 2017;7(1):13-27
American journal of cancer research 2017;7(1):13-27
Exogenous H(2)S restores ischemic post-conditioning-induced cardioprotection through inhibiting endoplasmic reticulum stress in the aged cardiomyocytes.
Sun W, Yang J, Zhang Y, Xi Y, Wen X, Yuan D, Wang Y, Wei C, Wang R, Wu L, Li H, Xu C
Cell & bioscience 2017;7:67
Cell & bioscience 2017;7:67
Oral Administration of Lactobacillus rhamnosus GG Ameliorates Salmonella Infantis-Induced Inflammation in a Pig Model via Activation of the IL-22BP/IL-22/STAT3 Pathway.
Yang GY, Yu J, Su JH, Jiao LG, Liu X, Zhu YH
Frontiers in cellular and infection microbiology 2017;7:323
Frontiers in cellular and infection microbiology 2017;7:323
In-Cell Western Assays to Evaluate Hantaan Virus Replication as a Novel Approach to Screen Antiviral Molecules and Detect Neutralizing Antibody Titers.
Ma HW, Ye W, Chen HS, Nie TJ, Cheng LF, Zhang L, Han PJ, Wu XA, Xu ZK, Lei YF, Zhang FL
Frontiers in cellular and infection microbiology 2017;7:269
Frontiers in cellular and infection microbiology 2017;7:269
Selenomethionine Attenuates the Amyloid-β Level by Both Inhibiting Amyloid-β Production and Modulating Autophagy in Neuron-2a/AβPPswe Cells.
Zhang ZH, Wu QY, Chen C, Zheng R, Chen Y, Liu Q, Ni JZ, Song GL
Journal of Alzheimer's disease : JAD 2017;59(2):591-602
Journal of Alzheimer's disease : JAD 2017;59(2):591-602
MiR-142-5p Suppresses Tumorigenesis by Targeting PIK3CA in Non-Small Cell Lung Cancer.
Wang Z, Liu Z, Fang X, Yang H
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2017;43(6):2505-2515
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2017;43(6):2505-2515
Iridoids with Genipin Stem Nucleus Inhibit Lipopolysaccharide-Induced Inflammation and Oxidative Stress by Blocking the NF-κB Pathway in Polycystic Ovary Syndrome.
Zuo T, Zhu M, Xu W, Wang Z, Song H
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2017;43(5):1855-1865
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2017;43(5):1855-1865
The USP7 Inhibitor P5091 Induces Cell Death in Ovarian Cancers with Different P53 Status.
Wang M, Zhang Y, Wang T, Zhang J, Zhou Z, Sun Y, Wang S, Shi Y, Luan X, Zhang Y, Wang Y, Wang Y, Zou Z, Kang L, Liu H
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2017;43(5):1755-1766
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2017;43(5):1755-1766
Involvement of S100A8/A9-TLR4-NLRP3 Inflammasome Pathway in Contrast-Induced Acute Kidney Injury.
Tan X, Zheng X, Huang Z, Lin J, Xie C, Lin Y
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2017;43(1):209-222
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2017;43(1):209-222
The Lncrna-TUG1/EZH2 Axis Promotes Pancreatic Cancer Cell Proliferation, Migration and EMT Phenotype Formation Through Sponging Mir-382.
Zhao L, Sun H, Kong H, Chen Z, Chen B, Zhou M
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2017;42(6):2145-2158
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2017;42(6):2145-2158
Deoxyelephantopin Induces Reactive Oxygen Species-Mediated Apoptosis and Autophagy in Human Osteosarcoma Cells.
Zou J, Zhang Y, Sun J, Wang X, Tu H, Geng S, Liu R, Chen Y, Bi Z
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2017;42(5):1812-1821
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2017;42(5):1812-1821
CDC5L Promotes hTERT Expression and Colorectal Tumor Growth.
Li J, Zhang N, Zhang R, Sun L, Yu W, Guo W, Gao Y, Li M, Liu W, Liang P, Deng W, Cui X
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2017;41(6):2475-2488
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2017;41(6):2475-2488
SOX6 Downregulation Induces γ-Globin in Human β-Thalassemia Major Erythroid Cells.
Li J, Lai Y, Luo J, Luo L, Liu R, Liu Z, Zhao W
BioMed research international 2017;2017:9496058
BioMed research international 2017;2017:9496058
Neutrophil Extracellular Traps Are Pathogenic in Ventilator-Induced Lung Injury and Partially Dependent on TLR4.
Li H, Pan P, Su X, Liu S, Zhang L, Wu D, Li H, Dai M, Li Y, Hu C, Chen J
BioMed research international 2017;2017:8272504
BioMed research international 2017;2017:8272504
Resveratrol Prevents ROS-Induced Apoptosis in High Glucose-Treated Retinal Capillary Endothelial Cells via the Activation of AMPK/Sirt1/PGC-1α Pathway.
Li J, Yu S, Ying J, Shi T, Wang P
Oxidative medicine and cellular longevity 2017;2017:7584691
Oxidative medicine and cellular longevity 2017;2017:7584691
Differentiation of Human Amniotic Mesenchymal Stem Cells into Human Anterior Cruciate Ligament Fibroblast Cells by In Vitro Coculture.
Li Y, Liu Z, Jin Y, Zhu X, Wang S, Yang J, Ren Y, Fu Q, Xiong H, Zou G, Liu Y
BioMed research international 2017;2017:7360354
BioMed research international 2017;2017:7360354
Antidiabetic Effect of Tibetan Medicine Tang-Kang-Fu-San on High-Fat Diet and Streptozotocin-Induced Type 2 Diabetic Rats.
Duan B, Zhao Z, Lin L, Jin J, Zhang L, Xiong H, Ta N, Gao T, Mei Z
Evidence-based complementary and alternative medicine : eCAM 2017;2017:7302965
Evidence-based complementary and alternative medicine : eCAM 2017;2017:7302965
Salusin-β Is Involved in Diabetes Mellitus-Induced Endothelial Dysfunction via Degradation of Peroxisome Proliferator-Activated Receptor Gamma.
Sun HJ, Chen D, Wang PY, Wan MY, Zhang CX, Zhang ZX, Lin W, Zhang F
Oxidative medicine and cellular longevity 2017;2017:6905217
Oxidative medicine and cellular longevity 2017;2017:6905217
Electroacupuncture Alleviates Postoperative Cognitive Dysfunction in Aged Rats by Inhibiting Hippocampal Neuroinflammation Activated via Microglia/TLRs Pathway.
Feng PP, Deng P, Liu LH, Ai Q, Yin J, Liu Z, Wang GM
Evidence-based complementary and alternative medicine : eCAM 2017;2017:6421260
Evidence-based complementary and alternative medicine : eCAM 2017;2017:6421260
HIV-1 Transactivator Protein Induces ZO-1 and Neprilysin Dysfunction in Brain Endothelial Cells via the Ras Signaling Pathway.
Jiang W, Huang W, Chen Y, Zou M, Peng D, Chen D
Oxidative medicine and cellular longevity 2017;2017:3160360
Oxidative medicine and cellular longevity 2017;2017:3160360
Long-Term Effects of TCM Yangqing Kangxian Formula on Bleomycin-Induced Pulmonary Fibrosis in Rats via Regulating Nuclear Factor-κB Signaling.
Li M, Li Y, Li J, Zhao P, Bai Y, Feng S, Liu X, Wang Y, Bian Q, Li J
Evidence-based complementary and alternative medicine : eCAM 2017;2017:2089027
Evidence-based complementary and alternative medicine : eCAM 2017;2017:2089027
Synthetic Isoliquiritigenin Inhibits Human Tongue Squamous Carcinoma Cells through Its Antioxidant Mechanism.
Hou C, Li W, Li Z, Gao J, Chen Z, Zhao X, Yang Y, Zhang X, Song Y
Oxidative medicine and cellular longevity 2017;2017:1379430
Oxidative medicine and cellular longevity 2017;2017:1379430
ROR2 receptor promotes the migration of osteosarcoma cells in response to Wnt5a.
Dai B, Yan T, Zhang A
Cancer cell international 2017;17:112
Cancer cell international 2017;17:112
HSPB8 Promotes the Fusion of Autophagosome and Lysosome during Autophagy in Diabetic Neurons.
Li XC, Hu QK, Chen L, Liu SY, Su S, Tao H, Zhang LN, Sun T, He LJ
International journal of medical sciences 2017;14(13):1335-1341
International journal of medical sciences 2017;14(13):1335-1341
LncRNA AFAP1-AS Functions as a Competing Endogenous RNA to Regulate RAP1B Expression by sponging miR-181a in the HSCR.
Chen G, Peng L, Zhu Z, Du C, Shen Z, Zang R, Su Y, Xia Y, Tang W
International journal of medical sciences 2017;14(10):1022-1030
International journal of medical sciences 2017;14(10):1022-1030
Exosomes Derived from Human Pulmonary Artery Endothelial Cells Shift the Balance between Proliferation and Apoptosis of Smooth Muscle Cells.
Zhao L, Luo H, Li X, Li T, He J, Qi Q, Liu Y, Yu Z
Cardiology 2017;137(1):43-53
Cardiology 2017;137(1):43-53
Resveratrol ameliorates diet-induced dysregulation of lipid metabolism in zebrafish (Danio rerio).
Ran G, Ying L, Li L, Yan Q, Yi W, Ying C, Wu H, Ye X
PloS one 2017;12(7):e0180865
PloS one 2017;12(7):e0180865
Caveolin1 protects against diet induced hepatic lipid accumulation in mice.
Li M, Chen D, Huang H, Wang J, Wan X, Xu C, Li C, Ma H, Yu C, Li Y
PloS one 2017;12(6):e0178748
PloS one 2017;12(6):e0178748
Imatinib attenuates cardiac fibrosis by inhibiting platelet-derived growth factor receptors activation in isoproterenol induced model.
Wang LX, Yang X, Yue Y, Fan T, Hou J, Chen GX, Liang MY, Wu ZK
PloS one 2017;12(6):e0178619
PloS one 2017;12(6):e0178619
A mutation in the CACNA1C gene leads to early repolarization syndrome with incomplete penetrance: A Chinese family study.
Liu X, Shen Y, Xie J, Bao H, Cao Q, Wan R, Xu X, Zhou H, Huang L, Xu Z, Zhu W, Hu J, Cheng X, Hong K
PloS one 2017;12(5):e0177532
PloS one 2017;12(5):e0177532
Role of keratin 24 in human epidermal keratinocytes.
Min M, Chen XB, Wang P, Landeck L, Chen JQ, Li W, Cai SQ, Zheng M, Man XY
PloS one 2017;12(3):e0174626
PloS one 2017;12(3):e0174626
Far-infrared suppresses skin photoaging in ultraviolet B-exposed fibroblasts and hairless mice.
Chiu HW, Chen CH, Chen YJ, Hsu YH
PloS one 2017;12(3):e0174042
PloS one 2017;12(3):e0174042
Increased expression of protein kinase CK2α correlates with poor patient prognosis in epithelial ovarian cancer.
Ma Z, Wang X, He J, Xia J, Li Y
PloS one 2017;12(3):e0174037
PloS one 2017;12(3):e0174037
Aerobic exercise regulates Rho/cofilin pathways to rescue synaptic loss in aged rats.
Li Y, Zhao L, Gu B, Cai J, Lv Y, Yu L
PloS one 2017;12(2):e0171491
PloS one 2017;12(2):e0171491
Rottlerin as a therapeutic approach in psoriasis: Evidence from in vitro and in vivo studies.
Min M, Yan BX, Wang P, Landeck L, Chen JQ, Li W, Cai SQ, Zheng M, Man XY
PloS one 2017;12(12):e0190051
PloS one 2017;12(12):e0190051
Down-regulation of the klf5-c-Myc interaction due to klf5 phosphorylation mediates resveratrol repressing the caveolin-1 transcription through the PI3K/PKD1/Akt pathway.
Yang H, Chen Q, Sun F, Zhao N, Wen L, Li L, Ran G
PloS one 2017;12(12):e0189156
PloS one 2017;12(12):e0189156
XRCC5 cooperates with p300 to promote cyclooxygenase-2 expression and tumor growth in colon cancers.
Zhang Z, Zheng F, Yu Z, Hao J, Chen M, Yu W, Guo W, Chen Y, Huang W, Duan Z, Deng W
PloS one 2017;12(10):e0186900
PloS one 2017;12(10):e0186900
MITA/STING and Its Alternative Splicing Isoform MRP Restrict Hepatitis B Virus Replication.
Liu S, Zhao K, Su X, Lu L, Zhao H, Zhang X, Wang Y, Wu C, Chen J, Zhou Y, Hu X, Wang Y, Lu M, Chen X, Pei R
PloS one 2017;12(1):e0169701
PloS one 2017;12(1):e0169701
Gold nanoparticles attenuate metastasis by tumor vasculature normalization and epithelial-mesenchymal transition inhibition.
Li W, Li X, Liu S, Yang W, Pan F, Yang XY, Du B, Qin L, Pan Y
International journal of nanomedicine 2017;12:3509-3520
International journal of nanomedicine 2017;12:3509-3520
Knockdown of Long Non-Coding RNA KCNQ1OT1 Restrained Glioma Cells' Malignancy by Activating miR-370/CCNE2 Axis.
Gong W, Zheng J, Liu X, Liu Y, Guo J, Gao Y, Tao W, Chen J, Li Z, Ma J, Xue Y
Frontiers in cellular neuroscience 2017;11:84
Frontiers in cellular neuroscience 2017;11:84
Involvement of endoplasmic reticulum stress in formalin-induced pain is attenuated by 4-phenylbutyric acid.
Zhou F, Zhang W, Zhou J, Li M, Zhong F, Zhang Y, Liu Y, Wang Y
Journal of pain research 2017;10:653-662
Journal of pain research 2017;10:653-662
UNBS5162 inhibits proliferation of human retinoblastoma cells by promoting cell apoptosis.
Wang B, Shen J, Wang J
OncoTargets and therapy 2017;10:5303-5309
OncoTargets and therapy 2017;10:5303-5309
The Effect of MCM3AP-AS1/miR-211/KLF5/AGGF1 Axis Regulating Glioblastoma Angiogenesis.
Yang C, Zheng J, Xue Y, Yu H, Liu X, Ma J, Liu L, Wang P, Li Z, Cai H, Liu Y
Frontiers in molecular neuroscience 2017;10:437
Frontiers in molecular neuroscience 2017;10:437
Circ-104916 is downregulated in gastric cancer and suppresses migration and invasion of gastric cancer cells.
Li J, Zhen L, Zhang Y, Zhao L, Liu H, Cai D, Chen H, Yu J, Qi X, Li G
OncoTargets and therapy 2017;10:3521-3529
OncoTargets and therapy 2017;10:3521-3529
PIK3CA expression in diffuse large B cell lymphoma tissue and the effect of its knockdown in vitro.
Cui W, Zheng S, Liu Z, Wang W, Cai Y, Bi R, Cao B, Zhou X
OncoTargets and therapy 2017;10:2239-2247
OncoTargets and therapy 2017;10:2239-2247
The Role of HOTAIR/miR-148b-3p/USF1 on Regulating the Permeability of BTB.
Sa L, Li Y, Zhao L, Liu Y, Wang P, Liu L, Li Z, Ma J, Cai H, Xue Y
Frontiers in molecular neuroscience 2017;10:194
Frontiers in molecular neuroscience 2017;10:194
Downregulation of the Repressor Element 1-Silencing Transcription Factor (REST) Is Associated with Akt-mTOR and Wnt-β-Catenin Signaling in Prion Diseases Models.
Song Z, Shah SZA, Yang W, Dong H, Yang L, Zhou X, Zhao D
Frontiers in molecular neuroscience 2017;10:128
Frontiers in molecular neuroscience 2017;10:128
Tail vein injection of mmLDL upregulates mouse mesenteric artery ET(B) receptors via activation of the ERK1/2 pathway.
Liu Y, Chen XL, Xu CB, Cao L, Lin J, Chen G, Li J
Vascular pharmacology 2017 Sep;96-98:33-39
Vascular pharmacology 2017 Sep;96-98:33-39
Calreticulin regulates TGF-β1-induced epithelial mesenchymal transition through modulating Smad signaling and calcium signaling.
Wu Y, Xu X, Ma L, Yi Q, Sun W, Tang L
The international journal of biochemistry & cell biology 2017 Sep;90:103-113
The international journal of biochemistry & cell biology 2017 Sep;90:103-113
Ehrlichia chaffeensis TRP120 Moonlights as a HECT E3 Ligase Involved in Self- and Host Ubiquitination To Influence Protein Interactions and Stability for Intracellular Survival.
Zhu B, Das S, Mitra S, Farris TR, McBride JW
Infection and immunity 2017 Sep;85(9)
Infection and immunity 2017 Sep;85(9)
Ligustrazine modulates renal cysteine biosynthesis in rats exposed to cadmium.
Kuang W, Zhang X, Zhu W, Lan Z
Environmental toxicology and pharmacology 2017 Sep;54:125-132
Environmental toxicology and pharmacology 2017 Sep;54:125-132
The transcription factor cyclic adenosine 3',5'-monophosphate response element-binding protein enhances the odonto/osteogenic differentiation of stem cells from the apical papilla.
Su S, Zhu Y, Li S, Liang Y, Zhang J
International endodontic journal 2017 Sep;50(9):885-894
International endodontic journal 2017 Sep;50(9):885-894
lncRNA-PVT1 Facilitates Invasion Through Upregulation of MMP9 in Nonsmall Cell Lung Cancer Cell.
Chen W, Zhu H, Yin L, Wang T, Wu J, Xu J, Tao H, Liu J, He X
DNA and cell biology 2017 Sep;36(9):787-793
DNA and cell biology 2017 Sep;36(9):787-793
Stool DNA Test of Methylated Syndecan-2 for the Early Detection of Colorectal Neoplasia.
Niu F, Wen J, Fu X, Li C, Zhao R, Wu S, Yu H, Liu X, Zhao X, Liu S, Wang X, Wang J, Zou H
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2017 Sep;26(9):1411-1419
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2017 Sep;26(9):1411-1419
Vertebrate Lonesome Kinase Regulated Extracellular Matrix Protein Phosphorylation, Cell Shape, and Adhesion in Trabecular Meshwork Cells.
Maddala R, Skiba NP, Rao PV
Journal of cellular physiology 2017 Sep;232(9):2447-2460
Journal of cellular physiology 2017 Sep;232(9):2447-2460
An oligodeoxynucleotide with AAAG repeats significantly attenuates burn-induced systemic inflammatory responses via inhibiting interferon regulatory factor 5 pathway.
Xiao Y, Lu W, Li X, Zhao P, Yao Y, Wang X, Wang Y, Lin Z, Yu Y, Hua S, Wang L
Molecular medicine (Cambridge, Mass.) 2017 Sep;23:166-176
Molecular medicine (Cambridge, Mass.) 2017 Sep;23:166-176
TNF-α promotes survival and migration of MSCs under oxidative stress via NF-κB pathway to attenuate intimal hyperplasia in vein grafts.
Bai X, Xi J, Bi Y, Zhao X, Bing W, Meng X, Liu Y, Zhu Z, Song G
Journal of cellular and molecular medicine 2017 Sep;21(9):2077-2091
Journal of cellular and molecular medicine 2017 Sep;21(9):2077-2091
Assessment of tris (1, 3-dichloro-2-propyl) phosphate toxicology in PC12 cells by using digital gene expression profiling.
Li L, Jiang S, Li K, Lin B, Wang Z, Zhang Z, Fang Y
Chemosphere 2017 Sep;183:353-360
Chemosphere 2017 Sep;183:353-360
Attenuation of doxorubicin-induced cardiotoxicity by esculetin through modulation of Bmi-1 expression.
Xu F, Li X, Liu L, Xiao X, Zhang L, Zhang S, Lin P, Wang X, Wang Y, Li Q
Experimental and therapeutic medicine 2017 Sep;14(3):2216-2220
Experimental and therapeutic medicine 2017 Sep;14(3):2216-2220
Dioscin, a potent ITGA5 inhibitor, reduces the synthesis of collagen against liver fibrosis: Insights from SILAC-based proteomics analysis.
Xu L, Yin L, Tao X, Qi Y, Han X, Xu Y, Song S, Li L, Sun P, Peng J
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2017 Sep;107(Pt A):318-328
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2017 Sep;107(Pt A):318-328
Predictive single nucleotide polymorphism markers for acute oral mucositis in patients with nasopharyngeal carcinoma treated with radiotherapy.
Le Z, Niu X, Chen Y, Ou X, Zhao G, Liu Q, Tu W, Hu C, Kong L, Liu Y
Oncotarget 2017 Sep 8;8(38):63026-63037
Oncotarget 2017 Sep 8;8(38):63026-63037
Hsp90 activator Aha1 drives production of pathological tau aggregates.
Shelton LB, Baker JD, Zheng D, Sullivan LE, Solanki PK, Webster JM, Sun Z, Sabbagh JJ, Nordhues BA, Koren J 3rd, Ghosh S, Blagg BSJ, Blair LJ, Dickey CA
Proceedings of the National Academy of Sciences of the United States of America 2017 Sep 5;114(36):9707-9712
Proceedings of the National Academy of Sciences of the United States of America 2017 Sep 5;114(36):9707-9712
Sirt6 deficiency exacerbates podocyte injury and proteinuria through targeting Notch signaling.
Liu M, Liang K, Zhen J, Zhou M, Wang X, Wang Z, Wei X, Zhang Y, Sun Y, Zhou Z, Su H, Zhang C, Li N, Gao C, Peng J, Yi F
Nature communications 2017 Sep 4;8(1):413
Nature communications 2017 Sep 4;8(1):413
FAM83D, a microtubule-associated protein, promotes tumor growth and progression of human gastric cancer.
Huang M, Ma X, Shi H, Hu L, Fan Z, Pang L, Zhu F, Yang X, Xu W, Liu B, Zhu Z, Li C
Oncotarget 2017 Sep 26;8(43):74479-74493
Oncotarget 2017 Sep 26;8(43):74479-74493
Numb positively regulates autophagic flux via regulating lysosomal function.
Sun H, Liu Y, Zhang L, Shao X, Liu K, Ding Z, Liu X, Jiang C, Li H, Li H
Biochemical and biophysical research communications 2017 Sep 23;491(3):780-786
Biochemical and biophysical research communications 2017 Sep 23;491(3):780-786
Overexpression of miR-135b-5p promotes unfavorable clinical characteristics and poor prognosis via the repression of SFRP4 in pancreatic cancer.
Han X, Saiyin H, Zhao J, Fang Y, Rong Y, Shi C, Lou W, Kuang T
Oncotarget 2017 Sep 22;8(37):62195-62207
Oncotarget 2017 Sep 22;8(37):62195-62207
Regulation of the epithelial Na(+) channel by paraoxonase-2.
Shi S, Buck TM, Kinlough CL, Marciszyn AL, Hughey RP, Chalfie M, Brodsky JL, Kleyman TR
The Journal of biological chemistry 2017 Sep 22;292(38):15927-15938
The Journal of biological chemistry 2017 Sep 22;292(38):15927-15938
Long non-coding RNA NEAT1 regulates epithelial membrane protein 2 expression to repress nasopharyngeal carcinoma migration and irradiation-resistance through miR-101-3p as a competing endogenous RNA mechanism.
Wang Y, Wang C, Chen C, Wu F, Shen P, Zhang P, He G, Li X
Oncotarget 2017 Sep 19;8(41):70156-70171
Oncotarget 2017 Sep 19;8(41):70156-70171
Heat-killed salmonella typhimurium (HKST) protects mice against radiation in TLR4-dependent manner.
Xu Y, Chen Y, Liu H, Lei X, Guo J, Cao K, Liu C, Li B, Cai J, Ju J, Gao F, Yang Y
Oncotarget 2017 Sep 15;8(40):67082-67093
Oncotarget 2017 Sep 15;8(40):67082-67093
Testosterone regulates 3T3-L1 pre-adipocyte differentiation and epididymal fat accumulation in mice through modulating macrophage polarization.
Ren X, Fu X, Zhang X, Chen S, Huang S, Yao L, Liu G
Biochemical pharmacology 2017 Sep 15;140:73-88
Biochemical pharmacology 2017 Sep 15;140:73-88
Cloning, expression pattern, and potential role of apoptosis inhibitor 5 in the termination of embryonic diapause and early embryo development of Artemia sinica.
Zhang S, Yao F, Jing T, Zhang M, Zhao W, Zou X, Sui L, Hou L
Gene 2017 Sep 10;628:170-179
Gene 2017 Sep 10;628:170-179
Ezrin as a possible diagnostic and/or prognostic biomarker in mice lymphatic metastatic hepatocellular carcinoma in vivo.
Bakheet AMH, Mahmoud SA, Huang Y, Zhang J, Wang J, Wei Y, Gamallat Y, Awadasseid A, Owusu L, Khidir Y, Wang L, Zhou S, Seewooruttun PK, Xin B, Xuan W, Su Z, Tang J
BioFactors (Oxford, England) 2017 Sep 10;43(5):662-672
BioFactors (Oxford, England) 2017 Sep 10;43(5):662-672
Phorbol esters dPPA/dPA promote furin expression involving transcription factor CEBPβ in neuronal cells.
Zha JS, Zhu BL, Liu L, Lai YJ, Long Y, Hu XT, Deng XJ, Wang XF, Yan Z, Chen GJ
Oncotarget 2017 Sep 1;8(36):60159-60172
Oncotarget 2017 Sep 1;8(36):60159-60172
Live-cell visualization of gasdermin D-driven pyroptotic cell death.
Rathkey JK, Benson BL, Chirieleison SM, Yang J, Xiao TS, Dubyak GR, Huang AY, Abbott DW
The Journal of biological chemistry 2017 Sep 1;292(35):14649-14658
The Journal of biological chemistry 2017 Sep 1;292(35):14649-14658
ORMDL3 Facilitates the Survival of Splenic B Cells via an ATF6α-Endoplasmic Reticulum Stress-Beclin1 Autophagy Regulatory Pathway.
Dang J, Bian X, Ma X, Li J, Long F, Shan S, Yuan Q, Xin Q, Li Y, Gao F, Gong Y, Liu Q
Journal of immunology (Baltimore, Md. : 1950) 2017 Sep 1;199(5):1647-1659
Journal of immunology (Baltimore, Md. : 1950) 2017 Sep 1;199(5):1647-1659
New Insights Into the Role of Estrogens in Male Fertility Based on Findings in Aromatase-Deficient Zebrafish.
Tang H, Chen Y, Liu Y, Yin Y, Li G, Guo Y, Liu X, Lin H
Endocrinology 2017 Sep 1;158(9):3042-3054
Endocrinology 2017 Sep 1;158(9):3042-3054
Lithium alleviates neurotoxic prion peptide-induced synaptic damage and neuronal death partially by the upregulation of nuclear target REST and the restoration of Wnt signaling.
Song Z, Yang W, Zhou X, Yang L, Zhao D
Neuropharmacology 2017 Sep 1;123:332-348
Neuropharmacology 2017 Sep 1;123:332-348
Role of Pannexin1 channels in the resistance of I-10 testicular cancer cells to cisplatin mediated by ATP/IP(3) pathway.
Wu D, Wu J, Liu H, Yu M, Tao L, Dong S, Tong X
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2017 Oct;94:514-522
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2017 Oct;94:514-522
Cadmium chloride-induced testicular toxicity in male wistar rats; prophylactic effect of quercetin, and assessment of testicular recovery following cadmium chloride withdrawal.
Nna VU, Ujah GA, Mohamed M, Etim KB, Igba BO, Augustine ER, Osim EE
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2017 Oct;94:109-123
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2017 Oct;94:109-123
In vitro anticancer activities of osthole against renal cell carcinoma cells.
Liu L, Mao J, Wang Q, Zhang Z, Wu G, Tang Q, Zhao B, Li L, Li Q
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2017 Oct;94:1020-1027
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2017 Oct;94:1020-1027
Metformin Inhibits Porphyromonas gingivalis Lipopolysaccharide-Influenced Inflammatory Response in Human Gingival Fibroblasts via Regulating Activating Transcription Factor-3 Expression.
Kang W, Wang T, Hu Z, Liu F, Sun Y, Ge S
Journal of periodontology 2017 Oct;88(10):e169-e178
Journal of periodontology 2017 Oct;88(10):e169-e178
A potential contribution of dipeptidyl peptidase-4 by the mediation of monocyte differentiation in the development and progression of abdominal aortic aneurysms.
Lu HY, Huang CY, Shih CM, Lin YW, Tsai CS, Lin FY, Shih CC
Journal of vascular surgery 2017 Oct;66(4):1217-1226.e1
Journal of vascular surgery 2017 Oct;66(4):1217-1226.e1
CISD2 enhances the chemosensitivity of gastric cancer through the enhancement of 5-FU-induced apoptosis and the inhibition of autophagy by AKT/mTOR pathway.
Sun Y, Jiang Y, Huang J, Chen H, Liao Y, Yang Z
Cancer medicine 2017 Oct;6(10):2331-2346
Cancer medicine 2017 Oct;6(10):2331-2346
Propofol inhibits invasion and proliferation of C6 glioma cells by regulating the Ca(2+) permeable AMPA receptor-system x(c)(-) pathway.
Wang XY, Li YL, Wang HY, Zhu M, Guo D, Wang GL, Gao YT, Yang Z, Li T, Yang CY, Chen YM
Toxicology in vitro : an international journal published in association with BIBRA 2017 Oct;44:57-65
Toxicology in vitro : an international journal published in association with BIBRA 2017 Oct;44:57-65
Trichostatin A attenuates oxidative stress-mediated myocardial injury through the FoxO3a signaling pathway.
Guo Y, Li Z, Shi C, Li J, Yao M, Chen X
International journal of molecular medicine 2017 Oct;40(4):999-1008
International journal of molecular medicine 2017 Oct;40(4):999-1008
Zinc finger protein 307 functions as a tumor‑suppressor and inhibits cell proliferation by inducing apoptosis in hepatocellular carcinoma.
Liang Y, Li Q, Chen K, Ni W, Zhan Z, Ye F, Li Y, Fang Y, Zhang F, Chen L, Ding Y
Oncology reports 2017 Oct;38(4):2229-2236
Oncology reports 2017 Oct;38(4):2229-2236
Varicella-zoster virus ORF7 interacts with ORF53 and plays a role in its trans-Golgi network localization.
Wang W, Fu W, Pan D, Cai L, Ye J, Liu J, Liu C, Que Y, Xia N, Zhu H, Cheng T
Virologica Sinica 2017 Oct;32(5):387-395
Virologica Sinica 2017 Oct;32(5):387-395
The effects of fluoride on neuronal function occurs via cytoskeleton damage and decreased signal transmission.
Chen L, Ning H, Yin Z, Song X, Feng Y, Qin H, Li Y, Wang J, Ge Y, Wang W
Chemosphere 2017 Oct;185:589-594
Chemosphere 2017 Oct;185:589-594
Proteasomal degradation of T. gondii ROP18 requires Derlin2.
Tang Y, Zheng M, An R, Chen L, Gong L, Cai H, Liu K, Yu L, Shen J, Du J
Acta tropica 2017 Oct;174:106-113
Acta tropica 2017 Oct;174:106-113
Dietary Selenium Deficiency or Excess Reduces Sperm Quality and Testicular mRNA Abundance of Nuclear Glutathione Peroxidase 4 in Rats.
Zhou JC, Zheng S, Mo J, Liang X, Xu Y, Zhang H, Gong C, Liu XL, Lei XG
The Journal of nutrition 2017 Oct;147(10):1947-1953
The Journal of nutrition 2017 Oct;147(10):1947-1953
ERβ compensates for the absence of ERα function to promote osteoblast viability by inhibition of SOST signaling.
Lu S, Sun C, Miao C, Zhao Z
Experimental and therapeutic medicine 2017 Oct;14(4):3387-3392
Experimental and therapeutic medicine 2017 Oct;14(4):3387-3392
Caveolin 1-related autophagy initiated by aldosterone-induced oxidation promotes liver sinusoidal endothelial cells defenestration.
Luo X, Dan Wang, Luo X, Zhu X, Wang G, Ning Z, Li Y, Ma X, Yang R, Jin S, Huang Y, Meng Y, Li X
Redox biology 2017 Oct;13:508-521
Redox biology 2017 Oct;13:508-521
Neuroprotective Effects of Loganin on MPTP-Induced Parkinson's Disease Mice: Neurochemistry, Glial Reaction and Autophagy Studies.
Xu YD, Cui C, Sun MF, Zhu YL, Chu M, Shi YW, Lin SL, Yang XS, Shen YQ
Journal of cellular biochemistry 2017 Oct;118(10):3495-3510
Journal of cellular biochemistry 2017 Oct;118(10):3495-3510
Ligustilide Relieves Complete Freund's Adjuvant-induced Mechanical Hyperalgesia through Inhibiting the Activation of Spinal c-Jun N-terminal Kinase/c-Jun Pathway in Rats.
Wang YR, Xu H, Tao M, Xu LH, Fu XC
Pharmacognosy magazine 2017 Oct-Dec;13(52):634-638
Pharmacognosy magazine 2017 Oct-Dec;13(52):634-638
RTN1-C mediates cerebral ischemia/reperfusion injury via ER stress and mitochondria-associated apoptosis pathways.
Gong L, Tang Y, An R, Lin M, Chen L, Du J
Cell death & disease 2017 Oct 5;8(10):e3080
Cell death & disease 2017 Oct 5;8(10):e3080
High expression of IL-4R enhances proliferation and invasion of hepatocellular carcinoma cells.
Guo C, Ouyang Y, Cai J, Xiong L, Chen Y, Zeng X, Liu A
The International journal of biological markers 2017 Oct 31;32(4):e384-e390
The International journal of biological markers 2017 Oct 31;32(4):e384-e390
Circular RNA HIPK2 regulates astrocyte activation via cooperation of autophagy and ER stress by targeting MIR124-2HG.
Huang R, Zhang Y, Han B, Bai Y, Zhou R, Gan G, Chao J, Hu G, Yao H
Autophagy 2017 Oct 3;13(10):1722-1741
Autophagy 2017 Oct 3;13(10):1722-1741
Calreticulin promotes EGF-induced EMT in pancreatic cancer cells via Integrin/EGFR-ERK/MAPK signaling pathway.
Sheng W, Chen C, Dong M, Wang G, Zhou J, Song H, Li Y, Zhang J, Ding S
Cell death & disease 2017 Oct 26;8(10):e3147
Cell death & disease 2017 Oct 26;8(10):e3147
ANP promotes proliferation and inhibits apoptosis of ovarian granulosa cells by NPRA/PGRMC1/EGFR complex and improves ovary functions of PCOS rats.
Zheng Q, Li Y, Zhang D, Cui X, Dai K, Yang Y, Liu S, Tan J, Yan Q
Cell death & disease 2017 Oct 26;8(10):e3145
Cell death & disease 2017 Oct 26;8(10):e3145
Protective Effect of Flavonoids from Ziziphus jujuba cv. Jinsixiaozao against Acetaminophen-Induced Liver Injury by Inhibiting Oxidative Stress and Inflammation in Mice.
Huang W, Wang Y, Jiang X, Sun Y, Zhao Z, Li S
Molecules (Basel, Switzerland) 2017 Oct 20;22(10)
Molecules (Basel, Switzerland) 2017 Oct 20;22(10)
Centriolin, a centriole-appendage protein, regulates peripheral spindle migration and asymmetric division in mouse meiotic oocytes.
Sun TY, Wang HY, Kwon JW, Yuan B, Lee IW, Cui XS, Kim NH
Cell cycle (Georgetown, Tex.) 2017 Oct 2;16(19):1774-1780
Cell cycle (Georgetown, Tex.) 2017 Oct 2;16(19):1774-1780
MicroRNA-20a-mediated loss of autophagy contributes to breast tumorigenesis by promoting genomic damage and instability.
Liu L, He J, Wei X, Wan G, Lao Y, Xu W, Li Z, Hu H, Hu Z, Luo X, Wu J, Xie W, Zhang Y, Xu N
Oncogene 2017 Oct 19;36(42):5874-5884
Oncogene 2017 Oct 19;36(42):5874-5884
Linc-RoR promotes MAPK/ERK signaling and confers estrogen-independent growth of breast cancer.
Peng WX, Huang JG, Yang L, Gong AH, Mo YY
Molecular cancer 2017 Oct 17;16(1):161
Molecular cancer 2017 Oct 17;16(1):161
MicroRNA-21 suppresses ox-LDL-induced human aortic endothelial cells injuries in atherosclerosis through enhancement of autophagic flux: Involvement in promotion of lysosomal function.
Tang F, Yang TL, Zhang Z, Li XG, Zhong QQ, Zhao TT, Gong L
Experimental cell research 2017 Oct 15;359(2):374-383
Experimental cell research 2017 Oct 15;359(2):374-383
Rab11a is required for porcine reproductive and respiratory syndrome virus induced autophagy to promote viral replication.
Wang K, Li S, Worku T, Hao X, Yang L, Zhang S
Biochemical and biophysical research communications 2017 Oct 14;492(2):236-242
Biochemical and biophysical research communications 2017 Oct 14;492(2):236-242
Aneuploid Cell Survival Relies upon Sphingolipid Homeostasis.
Tang YC, Yuwen H, Wang K, Bruno PM, Bullock K, Deik A, Santaguida S, Trakala M, Pfau SJ, Zhong N, Huang T, Wang L, Clish CB, Hemann MT, Amon A
Cancer research 2017 Oct 1;77(19):5272-5286
Cancer research 2017 Oct 1;77(19):5272-5286
Far infrared promotes wound healing through activation of Notch1 signaling.
Hsu YH, Lin YF, Chen CH, Chiu YJ, Chiu HW
Journal of molecular medicine (Berlin, Germany) 2017 Nov;95(11):1203-1213
Journal of molecular medicine (Berlin, Germany) 2017 Nov;95(11):1203-1213
Role of NF-κB/GATA3 in the inhibition of lysyl oxidase by IL-1β in human amnion fibroblasts.
Zhang C, Wang W, Liu C, Lu J, Sun K
Immunology and cell biology 2017 Nov;95(10):943-952
Immunology and cell biology 2017 Nov;95(10):943-952
Long non-coding RNA HOTTIP promotes hypoxia-induced epithelial-mesenchymal transition of malignant glioma by regulating the miR-101/ZEB1 axis.
Zhang S, Wang W, Liu G, Xie S, Li Q, Li Y, Lin Z
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2017 Nov;95:711-720
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2017 Nov;95:711-720
Berberine activates caspase-9/cytochrome c-mediated apoptosis to suppress triple-negative breast cancer cells in vitro and in vivo.
Zhao Y, Jing Z, Lv J, Zhang Z, Lin J, Cao X, Zhao Z, Liu P, Mao W
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2017 Nov;95:18-24
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2017 Nov;95:18-24
Spiroplasma eriocheiris induces mouse 3T6-Swiss albino cell apoptosis that associated with the infection mechanism.
Hou L, Gu W, Zhu H, Yao W, Wang W, Meng Q
Molecular immunology 2017 Nov;91:75-85
Molecular immunology 2017 Nov;91:75-85
Effects of melatonin on the proliferation and differentiation of human dental pulp cells.
Liu Q, Fan W, He Y, Zhang F, Guan X, Deng Q, Lu X, He H, Huang F
Archives of oral biology 2017 Nov;83:33-39
Archives of oral biology 2017 Nov;83:33-39
MYC protein dysregulation is driven by BCR-PI3K signalling in diffuse large B-cell lymphoma.
Wang WG, Liu ZB, Jiang XN, Lee J, Zhou XY, Li XQ
Histopathology 2017 Nov;71(5):778-785
Histopathology 2017 Nov;71(5):778-785
Effectively enhancing cytotoxic and apoptotic effects of alpha-momorcharin by integrating a heparin-binding peptide.
Tan MJ, Cao XW, Li PF, Zhai YZ, Zhou Y, Liu YJ, Zhao J, Wang FJ
Biotechnology and applied biochemistry 2017 Nov;64(6):918-926
Biotechnology and applied biochemistry 2017 Nov;64(6):918-926
Artesunate induces apoptosis via inhibition of STAT3 in THP-1 cells.
Tan M, Rong Y, Su Q, Chen Y
Leukemia research 2017 Nov;62:98-103
Leukemia research 2017 Nov;62:98-103
MAPK/p38 regulation of cytoskeleton rearrangement accelerates induction of macrophage activation by TLR4, but not TLR3.
Bian H, Li F, Wang W, Zhao Q, Gao S, Ma J, Li X, Ren W, Qin C, Qi J
International journal of molecular medicine 2017 Nov;40(5):1495-1503
International journal of molecular medicine 2017 Nov;40(5):1495-1503
Platelet rich plasma promotes skeletal muscle cell migration in association with up-regulation of FAK, paxillin, and F-Actin formation.
Tsai WC, Yu TY, Lin LP, Lin MS, Tsai TT, Pang JS
Journal of orthopaedic research : official publication of the Orthopaedic Research Society 2017 Nov;35(11):2506-2512
Journal of orthopaedic research : official publication of the Orthopaedic Research Society 2017 Nov;35(11):2506-2512
Endothelial cell SHP-2 negatively regulates neutrophil adhesion and promotes transmigration by enhancing ICAM-1-VE-cadherin interaction.
Yan M, Zhang X, Chen A, Gu W, Liu J, Ren X, Zhang J, Wu X, Place AT, Minshall RD, Liu G
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2017 Nov;31(11):4759-4769
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2017 Nov;31(11):4759-4769
Sodium selenate activated Wnt/β-catenin signaling and repressed amyloid-β formation in a triple transgenic mouse model of Alzheimer's disease.
Jin N, Zhu H, Liang X, Huang W, Xie Q, Xiao P, Ni J, Liu Q
Experimental neurology 2017 Nov;297:36-49
Experimental neurology 2017 Nov;297:36-49
Neuroprotection of hypoxic postconditioning against global cerebral ischemia through influencing posttranslational regulations of heat shock protein 27 in adult rats.
Zhan L, Liu L, Li K, Wu B, Liu D, Liang D, Wen H, Wang Y, Sun W, Liao W, Xu E
Brain pathology (Zurich, Switzerland) 2017 Nov;27(6):822-838
Brain pathology (Zurich, Switzerland) 2017 Nov;27(6):822-838
Rho-kinase inhibitor Y-27632 facilitates the proliferation, migration and pluripotency of human periodontal ligament stem cells.
Wang T, Kang W, Du L, Ge S
Journal of cellular and molecular medicine 2017 Nov;21(11):3100-3112
Journal of cellular and molecular medicine 2017 Nov;21(11):3100-3112
Focal adhesion kinase family is involved in matrix contraction by transdifferentiated Müller cells.
Tsukahara R, Umazume K, McDonald K, Kaplan HJ, Tamiya S
Experimental eye research 2017 Nov;164:90-94
Experimental eye research 2017 Nov;164:90-94
IFNA2 p.Ala120Thr impairs the inhibitory activity of Interferon-α2 against the hepatitis B virus through altering its binding to the receptor.
Chen C, Zhu X, Xu W, Yang F, Zhang G, Wu L, Zheng Y, Gao Z, Xie C, Peng L
Antiviral research 2017 Nov;147:11-18
Antiviral research 2017 Nov;147:11-18
Reactive oxygen species-responsive polymeric nanoparticles for alleviating sepsis-induced acute liver injury in mice.
Chen G, Deng H, Song X, Lu M, Zhao L, Xia S, You G, Zhao J, Zhang Y, Dong A, Zhou H
Biomaterials 2017 Nov;144:30-41
Biomaterials 2017 Nov;144:30-41
Downregulated long non-coding RNA TCONS_00068220 upregulates apoptosis in gastric cancer cells.
Zhao Z, Xue J, Song Y, Liu T, Piao D
Oncology letters 2017 Nov;14(5):6143-6150
Oncology letters 2017 Nov;14(5):6143-6150
p63 inhibits CD44(+)/CD24(-) cell proliferation and chemoresistance in papillary thyroid carcinoma cells.
Guo JJ, Xu HS, Wu G, Ma ZY
Experimental and therapeutic medicine 2017 Nov;14(5):4693-4696
Experimental and therapeutic medicine 2017 Nov;14(5):4693-4696
Generation of apoptosis-resistant HEK293 cells with CRISPR/Cas mediated quadruple gene knockout for improved protein and virus production.
Zhang W, Xiao D, Shan L, Zhao J, Mao Q, Xia H
Biotechnology and bioengineering 2017 Nov;114(11):2539-2549
Biotechnology and bioengineering 2017 Nov;114(11):2539-2549
β-d-glucan from Antrodia Camphorata ameliorates LPS-induced inflammation and ROS production in human hepatocytes.
Chen Q, Tang H, Zha Z, Yin H, Wang Y, Wang Y, Li H, Yue L
International journal of biological macromolecules 2017 Nov;104(Pt A):768-777
International journal of biological macromolecules 2017 Nov;104(Pt A):768-777
Cell contact and pressure control of YAP localization and clustering revealed by super-resolution imaging.
Gao J, He L, Shi Y, Cai M, Xu H, Jiang J, Zhang L, Wang H
Nanoscale 2017 Nov 9;9(43):16993-17003
Nanoscale 2017 Nov 9;9(43):16993-17003
Insulin-like growth factor 2 mRNA binding protein 3 (IGF2BP3) promotes lung tumorigenesis via attenuating p53 stability.
Zhao W, Lu D, Liu L, Cai J, Zhou Y, Yang Y, Zhang Y, Zhang J
Oncotarget 2017 Nov 7;8(55):93672-93687
Oncotarget 2017 Nov 7;8(55):93672-93687
Targeted Metabolomics Reveals Abnormal Hepatic Energy Metabolism by Depletion of β-Carotene Oxygenase 2 in Mice.
Wu L, Guo X, Lyu Y, Clarke SL, Lucas EA, Smith BJ, Hildebrand D, Wang W, Medeiros DM, Shen X, Lin D
Scientific reports 2017 Nov 7;7(1):14624
Scientific reports 2017 Nov 7;7(1):14624
DC2 and KCP2 mediate the interaction between the oligosaccharyltransferase and the ER translocon.
Shrimal S, Cherepanova NA, Gilmore R
The Journal of cell biology 2017 Nov 6;216(11):3625-3638
The Journal of cell biology 2017 Nov 6;216(11):3625-3638
Curcumin inhibits bladder cancer stem cells by suppressing Sonic Hedgehog pathway.
Wang D, Kong X, Li Y, Qian W, Ma J, Wang D, Yu D, Zhong C
Biochemical and biophysical research communications 2017 Nov 4;493(1):521-527
Biochemical and biophysical research communications 2017 Nov 4;493(1):521-527
Upregulation of SOX2 activated LncRNA PVT1 expression promotes breast cancer cell growth and invasion.
Wang Y, Zhou J, Wang Z, Wang P, Li S
Biochemical and biophysical research communications 2017 Nov 4;493(1):429-436
Biochemical and biophysical research communications 2017 Nov 4;493(1):429-436
Cholecalciterol cholesterol emulsion attenuates experimental autoimmune myocarditis in mice via inhibition of the pyroptosis signaling pathway.
Liu N, Su H, Zhang Y, Liu Z, Kong J
Biochemical and biophysical research communications 2017 Nov 4;493(1):422-428
Biochemical and biophysical research communications 2017 Nov 4;493(1):422-428
Autocrine Interleukin-10 Mediates Glucagon-Like Peptide-1 Receptor-Induced Spinal Microglial β-Endorphin Expression.
Wu HY, Tang XQ, Mao XF, Wang YX
The Journal of neuroscience : the official journal of the Society for Neuroscience 2017 Nov 29;37(48):11701-11714
The Journal of neuroscience : the official journal of the Society for Neuroscience 2017 Nov 29;37(48):11701-11714
Metformin reverses bFGF-induced epithelial-mesenchymal transition in HCC cells.
Chengye W, Yu T, Ping S, Deguang S, Keyun W, Yan W, Rixin Z, Rui L, Zhenming G, Mingliang Y, Liming W
Oncotarget 2017 Nov 28;8(61):104247-104257
Oncotarget 2017 Nov 28;8(61):104247-104257
MiR-16-5p mediates a positive feedback loop in EV71-induced apoptosis and suppresses virus replication.
Zheng C, Zheng Z, Sun J, Zhang Y, Wei C, Ke X, Liu Y, Deng L, Wang H
Scientific reports 2017 Nov 27;7(1):16422
Scientific reports 2017 Nov 27;7(1):16422
Proteomics and metabolomics analysis of hepatic mitochondrial metabolism in alcohol-preferring and non-preferring rats.
Zeng HL, Yang Q, Du H, Li H, Shen Y, Liu T, Chen X, Kamal GM, Guan Q, Cheng L, Wang J, Xu F
Oncotarget 2017 Nov 24;8(60):102020-102032
Oncotarget 2017 Nov 24;8(60):102020-102032
Pim-3 as a potential predictor of chemoradiotherapy resistance in locally advanced rectal cancer patients.
Zhang RX, Zhou ZG, Lu SX, Lu ZH, Wan DS, Pan ZZ, Wu XJ, Chen G
Scientific reports 2017 Nov 22;7(1):16043
Scientific reports 2017 Nov 22;7(1):16043
AKAP95-mediated nuclear anchoring of PKA mediates cortisol-induced PTGS2 expression in human amnion fibroblasts.
Lu J, Wang W, Mi Y, Zhang C, Ying H, Wang L, Wang Y, Myatt L, Sun K
Science signaling 2017 Nov 21;10(506)
Science signaling 2017 Nov 21;10(506)
Levels of Leydig cell autophagy regulate the fertility of male naked mole-rats.
Yang W, Li L, Huang X, Kan G, Lin L, Cheng J, Xu C, Sun W, Cong W, Zhao S, Cui S
Oncotarget 2017 Nov 17;8(58):98677-98690
Oncotarget 2017 Nov 17;8(58):98677-98690
High expression of PDLIM5 facilitates cell tumorigenesis and migration by maintaining AMPK activation in prostate cancer.
Liu X, Chen L, Huang H, Lv JM, Chen M, Qu FJ, Pan XW, Li L, Yin L, Cui XG, Gao Y, Xu DF
Oncotarget 2017 Nov 17;8(58):98117-98134
Oncotarget 2017 Nov 17;8(58):98117-98134
Different miR-21-3p isoforms and their different features in colorectal cancer.
Jiao W, Leng X, Zhou Q, Wu Y, Sun L, Tan Y, Ni H, Dong X, Shen T, Liu Y, Li J
International journal of cancer 2017 Nov 15;141(10):2103-2111
International journal of cancer 2017 Nov 15;141(10):2103-2111
DLX3 promotes bone marrow mesenchymal stem cell proliferation through H19/miR-675 axis.
Zhao N, Zeng L, Liu Y, Han D, Liu H, Xu J, Jiang Y, Li C, Cai T, Feng H, Wang Y
Clinical science (London, England : 1979) 2017 Nov 15;131(22):2721-2735
Clinical science (London, England : 1979) 2017 Nov 15;131(22):2721-2735
Quercetin exerts synergetic anti-cancer activity with 10-hydroxy camptothecin.
Tang Q, Ji F, Wang J, Guo L, Li Y, Bao Y
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2017 Nov 15;109:223-232
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2017 Nov 15;109:223-232
Bcl-3 is a novel biomarker of renal fibrosis in chronic kidney disease.
Chen R, Wang L, Liu S, Chen X, Hu Y, Liu H, Zhang H, Jiang Y, Wang Q, Ye D, Li L, Liu D, Pan X, Wei L, Li X, Zhang X
Oncotarget 2017 Nov 14;8(57):97206-97216
Oncotarget 2017 Nov 14;8(57):97206-97216
FBXW8-dependent degradation of MRFAP1 in anaphase controls mitotic cell death.
Li DZ, Liu SF, Zhu L, Wang YX, Chen YX, Liu J, Hu G, Yu X, Li J, Zhang J, Wu ZX, Lu H, Liu W, Liu B
Oncotarget 2017 Nov 14;8(57):97178-97186
Oncotarget 2017 Nov 14;8(57):97178-97186
Comparative study of macrophages in naked mole rats and ICR mice.
Cheng J, Yuan Z, Yang W, Xu C, Cong W, Lin L, Zhao S, Sun W, Bai X, Cui S
Oncotarget 2017 Nov 14;8(57):96924-96934
Oncotarget 2017 Nov 14;8(57):96924-96934
iASPP Is an Antioxidative Factor and Drives Cancer Growth and Drug Resistance by Competing with Nrf2 for Keap1 Binding.
Ge W, Zhao K, Wang X, Li H, Yu M, He M, Xue X, Zhu Y, Zhang C, Cheng Y, Jiang S, Hu Y
Cancer cell 2017 Nov 13;32(5):561-573.e6
Cancer cell 2017 Nov 13;32(5):561-573.e6
CHST6 mutation screening and endoplasmatic reticulum stress in macular corneal dystrophy.
Wang L, Tang X, Lv X, Sun E, Wu D, Wang C, Liu P
Oncotarget 2017 Nov 10;8(56):96301-96312
Oncotarget 2017 Nov 10;8(56):96301-96312
KSRP specifies monocytic and granulocytic differentiation through regulating miR-129 biogenesis and RUNX1 expression.
Zhao H, Wang X, Yi P, Si Y, Tan P, He J, Yu S, Ren Y, Ma Y, Zhang J, Wang D, Wang F, Yu J
Nature communications 2017 Nov 10;8(1):1428
Nature communications 2017 Nov 10;8(1):1428
A Single-Amino-Acid Substitution at Position 225 in Hemagglutinin Alters the Transmissibility of Eurasian Avian-Like H1N1 Swine Influenza Virus in Guinea Pigs.
Wang Z, Yang H, Chen Y, Tao S, Liu L, Kong H, Ma S, Meng F, Suzuki Y, Qiao C, Chen H
Journal of virology 2017 Nov 1;91(21)
Journal of virology 2017 Nov 1;91(21)
Expression and Subcellular Localization of the Kaposi's Sarcoma-Associated Herpesvirus K15P Protein during Latency and Lytic Reactivation in Primary Effusion Lymphoma Cells.
Smith CG, Kharkwal H, Wilson DW
Journal of virology 2017 Nov 1;91(21)
Journal of virology 2017 Nov 1;91(21)
HERP Binds TBK1 To Activate Innate Immunity and Repress Virus Replication in Response to Endoplasmic Reticulum Stress.
Ge M, Luo Z, Qiao Z, Zhou Y, Cheng X, Geng Q, Cai Y, Wan P, Xiong Y, Liu F, Wu K, Liu Y, Wu J
Journal of immunology (Baltimore, Md. : 1950) 2017 Nov 1;199(9):3280-3292
Journal of immunology (Baltimore, Md. : 1950) 2017 Nov 1;199(9):3280-3292
Designed inhibitor for nuclear localization signal of polo-like kinase 1 induces mitotic arrest.
Chen F, Zhuo X, Qin T, Guo X, Zhang C, Lai L
Chemical biology & drug design 2017 May;89(5):732-740
Chemical biology & drug design 2017 May;89(5):732-740
The tumor suppressor p53 regulates autophagosomal and lysosomal biogenesis in lung cancer cells by targeting transcription factor EB.
Zhang Z, Wang H, Ding Q, Xing Y, Xu D, Xu Z, Zhou T, Qian B, Ji C, Pan X, Zhong A, Ying Z, Zhou C, Shi M
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2017 May;89:1055-1060
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2017 May;89:1055-1060
DLX3 mutation negatively regulates odontogenic differentiation of human dental pulp cells.
Zeng L, Zhao N, Han D, Liu H, Liu Y, Wang Y, Feng H
Archives of oral biology 2017 May;77:12-17
Archives of oral biology 2017 May;77:12-17
Cynandione A attenuates neuropathic pain through p38β MAPK-mediated spinal microglial expression of β-endorphin.
Huang Q, Mao XF, Wu HY, Liu H, Sun ML, Wang X, Wang YX
Brain, behavior, and immunity 2017 May;62:64-77
Brain, behavior, and immunity 2017 May;62:64-77
Involvement of FMRP in Primary MicroRNA Processing via Enhancing Drosha Translation.
Wan RP, Zhou LT, Yang HX, Zhou YT, Ye SH, Zhao QH, Gao MM, Liao WP, Yi YH, Long YS
Molecular neurobiology 2017 May;54(4):2585-2594
Molecular neurobiology 2017 May;54(4):2585-2594
The mechanism of epithelial-mesenchymal transition induced by TGF-β1 in neuroblastoma cells.
Shao JB, Gao ZM, Huang WY, Lu ZB
International journal of oncology 2017 May;50(5):1623-1633
International journal of oncology 2017 May;50(5):1623-1633
E-Prostanoid 3 Receptor Mediates Sprouting Angiogenesis Through Suppression of the Protein Kinase A/β-Catenin/Notch Pathway.
Chen D, Tang J, Wan Q, Zhang J, Wang K, Shen Y, Yu Y
Arteriosclerosis, thrombosis, and vascular biology 2017 May;37(5):856-866
Arteriosclerosis, thrombosis, and vascular biology 2017 May;37(5):856-866
Human recombinant RNASET2-induced inflammatory response and connective tissue remodeling in the medicinal leech.
Baranzini N, Pedrini E, Girardello R, Tettamanti G, de Eguileor M, Taramelli R, Acquati F, Grimaldi A
Cell and tissue research 2017 May;368(2):337-351
Cell and tissue research 2017 May;368(2):337-351
Fn14 hepatic progenitor cells are associated with liver fibrosis in biliary atresia.
Zheng L, Lv Z, Gong Z, Sheng Q, Gao Z, Zhang Y, Yu S, Zhou J, Xi Z, Wang X
Pediatric surgery international 2017 May;33(5):593-599
Pediatric surgery international 2017 May;33(5):593-599
Shen-Yuan-Dan Capsule Inhibiting Inflammatory Reaction by Regulating Insulin Receptor Substrate 1/PI3K/Akt/NF-κB Signaling Pathway in Apoliprotein E Knockout Mice Fed with a High-Fat Diet.
Zhou M, Li P, Kang Q, Zhang L, Shang J, Liu W, Liu H
Acta Cardiologica Sinica 2017 May;33(3):285-291
Acta Cardiologica Sinica 2017 May;33(3):285-291
Clinical Significance and Tumor-Suppressive Function of miR-516b in Nonsmall Cell Lung Cancer.
Zhu J, Zhang Y, Yang X, Jin L
Cancer biotherapy & radiopharmaceuticals 2017 May;32(4):115-123
Cancer biotherapy & radiopharmaceuticals 2017 May;32(4):115-123
Lethal concentration of perfluoroisobutylene induces acute lung injury in mice mediated via cytokine storm, oxidative stress and apoptosis.
Zhang Y, Fan L, Xi R, Mao Z, Shi D, Ding D, Zhang Z, Wang X
Inhalation toxicology 2017 May;29(6):255-265
Inhalation toxicology 2017 May;29(6):255-265
BNIP3 promotes the motility and migration of keratinocyte under hypoxia.
Zhang J, Zhang D, Yan T, Jiang X, Zhang C, Zhao L, Li L, Tang D, Zhang Q, Jia J, Zhang J, Huang Y
Experimental dermatology 2017 May;26(5):416-422
Experimental dermatology 2017 May;26(5):416-422
TSA protects H9c2 cells against thapsigargin-induced apoptosis related to endoplasmic reticulum stress-mediated mitochondrial injury.
Li Z, Liu Y, Dai X, Zhou Q, Liu X, Li Z, Chen X
Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society 2017 May;25(4):595-600
Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society 2017 May;25(4):595-600
lncRNA-HIT promotes cell proliferation of non-small cell lung cancer by association with E2F1.
Yu L, Fang F, Lu S, Li X, Yang Y, Wang Z
Cancer gene therapy 2017 May;24(5):221-226
Cancer gene therapy 2017 May;24(5):221-226
EphrinB-EphB Signaling Induces Hyperalgesia through ERK5/CREB Pathway in Rats.
Yu LN, Sun LH, Wang M, Wang LJ, Wu Y, Yu J, Wang WN, Zhang FJ, Li X, Yan M
Pain physician 2017 May;20(4):E563-E574
Pain physician 2017 May;20(4):E563-E574
siRNA-mediated knockdown of ID1 disrupts Nanog- and Oct-4-mediated cancer stem cell-likeness and resistance to chemotherapy in gastric cancer cells.
Li L, Wei X, Wu B, Xiao Y, Yin M, Yang Q
Oncology letters 2017 May;13(5):3014-3024
Oncology letters 2017 May;13(5):3014-3024
PCSK9 regulates apoptosis in human lung adenocarcinoma A549 cells via endoplasmic reticulum stress and mitochondrial signaling pathways.
Xu X, Cui Y, Cao L, Zhang Y, Yin Y, Hu X
Experimental and therapeutic medicine 2017 May;13(5):1993-1999
Experimental and therapeutic medicine 2017 May;13(5):1993-1999
Dihydroartemisin inhibits glioma invasiveness via a ROS to P53 to β-catenin signaling.
Que Z, Wang P, Hu Y, Xue Y, Liu X, Qu C, Ma J, Liu Y
Pharmacological research 2017 May;119:72-88
Pharmacological research 2017 May;119:72-88
Galectin-3 mediates the pulmonary arterial hypertension-induced right ventricular remodeling through interacting with NADPH oxidase 4.
He J, Li X, Luo H, Li T, Zhao L, Qi Q, Liu Y, Yu Z
Journal of the American Society of Hypertension : JASH 2017 May;11(5):275-289.e2
Journal of the American Society of Hypertension : JASH 2017 May;11(5):275-289.e2
A novel inducible lentiviral system for multi-gene expression with human HSP70 promoter and tetracycline-induced promoter.
Li S, Ma L, Ou M, Feng J, Liao Y, Wang G, Tang L
Applied microbiology and biotechnology 2017 May;101(9):3689-3702
Applied microbiology and biotechnology 2017 May;101(9):3689-3702
Upregulation of the lncRNA Meg3 induces autophagy to inhibit tumorigenesis and progression of epithelial ovarian carcinoma by regulating activity of ATG3.
Xiu YL, Sun KX, Chen X, Chen S, Zhao Y, Guo QG, Zong ZH
Oncotarget 2017 May 9;8(19):31714-31725
Oncotarget 2017 May 9;8(19):31714-31725
Atgl gene deletion predisposes to proximal tubule damage by impairing the fatty acid metabolism.
Chen W, Zhang Q, Cheng S, Huang J, Diao G, Han J
Biochemical and biophysical research communications 2017 May 20;487(1):160-166
Biochemical and biophysical research communications 2017 May 20;487(1):160-166
miR-29a regulated ER-positive breast cancer cell growth and invasion and is involved in the insulin signaling pathway.
Li ZH, Xiong QY, Xu L, Duan P, Yang QO, Zhou P, Tu JH
Oncotarget 2017 May 16;8(20):32566-32575
Oncotarget 2017 May 16;8(20):32566-32575
Fatty acid synthesis is critical for stem cell pluripotency via promoting mitochondrial fission.
Wang L, Zhang T, Wang L, Cai Y, Zhong X, He X, Hu L, Tian S, Wu M, Hui L, Zhang H, Gao P
The EMBO journal 2017 May 15;36(10):1330-1347
The EMBO journal 2017 May 15;36(10):1330-1347
MiR-23a-5p modulates mycobacterial survival and autophagy during mycobacterium tuberculosis infection through TLR2/MyD88/NF-κB pathway by targeting TLR2.
Gu X, Gao Y, Mu DG, Fu EQ
Experimental cell research 2017 May 15;354(2):71-77
Experimental cell research 2017 May 15;354(2):71-77
A critical role of Hrd1 in the regulation of optineurin degradation and aggresome formation.
Mao J, Xia Q, Liu C, Ying Z, Wang H, Wang G
Human molecular genetics 2017 May 15;26(10):1877-1889
Human molecular genetics 2017 May 15;26(10):1877-1889
Identification and activation of TLR4-mediated signalling pathways by alginate-derived guluronate oligosaccharide in RAW264.7 macrophages.
Fang W, Bi D, Zheng R, Cai N, Xu H, Zhou R, Lu J, Wan M, Xu X
Scientific reports 2017 May 10;7(1):1663
Scientific reports 2017 May 10;7(1):1663
CRISPR/Cas9 Screens Reveal Epstein-Barr Virus-Transformed B Cell Host Dependency Factors.
Ma Y, Walsh MJ, Bernhardt K, Ashbaugh CW, Trudeau SJ, Ashbaugh IY, Jiang S, Jiang C, Zhao B, Root DE, Doench JG, Gewurz BE
Cell host & microbe 2017 May 10;21(5):580-591.e7
Cell host & microbe 2017 May 10;21(5):580-591.e7
Chromium contributes to human bronchial epithelial cell carcinogenesis by activating Gli2 and inhibiting autophagy.
Huang J, Wu G, Zeng R, Wang J, Cai R, Ho JC, Zhang J, Zheng Y
Toxicology research 2017 May 1;6(3):324-332
Toxicology research 2017 May 1;6(3):324-332
7-O-Geranylquercetin induces apoptosis in gastric cancer cells via ROS-MAPK mediated mitochondrial signaling pathway activation.
Zhu Y, Jiang Y, Shi L, Du L, Xu X, Wang E, Sun Y, Guo X, Zou B, Wang H, Wang C, Sun L, Zhen Y
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2017 Mar;87:527-538
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2017 Mar;87:527-538
Vascular endothelial cells senescence is associated with NOD-like receptor family pyrin domain-containing 3 (NLRP3) inflammasome activation via reactive oxygen species (ROS)/thioredoxin-interacting protein (TXNIP) pathway.
Yin Y, Zhou Z, Liu W, Chang Q, Sun G, Dai Y
The international journal of biochemistry & cell biology 2017 Mar;84:22-34
The international journal of biochemistry & cell biology 2017 Mar;84:22-34
Melatonin synergizes the chemotherapeutic effect of 5-fluorouracil in colon cancer by suppressing PI3K/AKT and NF-κB/iNOS signaling pathways.
Gao Y, Xiao X, Zhang C, Yu W, Guo W, Zhang Z, Li Z, Feng X, Hao J, Zhang K, Xiao B, Chen M, Huang W, Xiong S, Wu X, Deng W
Journal of pineal research 2017 Mar;62(2)
Journal of pineal research 2017 Mar;62(2)
Hepatic deletion of X-box binding protein 1 impairs bile acid metabolism in mice.
Liu X, Henkel AS, LeCuyer BE, Hubchak SC, Schipma MJ, Zhang E, Green RM
Journal of lipid research 2017 Mar;58(3):504-511
Journal of lipid research 2017 Mar;58(3):504-511
PBDE-209 exposure damages learning and memory ability in rats potentially through increased autophagy and apoptosis in the hippocampus neuron.
Sun W, Du L, Tang W, Kuang L, Du P, Chen J, Chen D
Environmental toxicology and pharmacology 2017 Mar;50:151-158
Environmental toxicology and pharmacology 2017 Mar;50:151-158
miR-194 functions as a novel modulator of cellular senescence in mouse embryonic fibroblasts.
Xu S, Zhang B, Zhu Y, Huang H, Yang W, Huang H, Zheng HL, Liu X
Cell biology international 2017 Mar;41(3):249-257
Cell biology international 2017 Mar;41(3):249-257
High mobility group box 1/toll-like receptor 4/myeloid differentiation factor 88 signaling promotes progression of gastric cancer.
Yue Y, Zhou T, Gao Y, Zhang Z, Li L, Liu L, Shi W, Su L, Cheng B
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2017 Mar;39(3):1010428317694312
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2017 Mar;39(3):1010428317694312
MicroRNA-133b is regulated by TAp63 while no gene mutation is present in colorectal cancer.
Chen Y, Zhang Y, He J, Fu Y, Lin C, Li X
Oncology reports 2017 Mar;37(3):1646-1652
Oncology reports 2017 Mar;37(3):1646-1652
Knockdown of NUPR1 inhibits the proliferation of glioblastoma cells via ERK1/2, p38 MAPK and caspase-3.
Li J, Ren S, Liu Y, Lian Z, Dong B, Yao Y, Xu Y
Journal of neuro-oncology 2017 Mar;132(1):15-26
Journal of neuro-oncology 2017 Mar;132(1):15-26
Conditional knockout of Fgf13 in murine hearts increases arrhythmia susceptibility and reveals novel ion channel modulatory roles.
Wang X, Tang H, Wei EQ, Wang Z, Yang J, Yang R, Wang S, Zhang Y, Pitt GS, Zhang H, Wang C
Journal of molecular and cellular cardiology 2017 Mar;104:63-74
Journal of molecular and cellular cardiology 2017 Mar;104:63-74
Epidermal CD147 expression plays a key role in IL-22-induced psoriatic dermatitis.
Peng C, Zhang S, Lei L, Zhang X, Jia X, Luo Z, Huang X, Kuang Y, Zeng W, Su J, Chen X
Scientific reports 2017 Mar 8;7:44172
Scientific reports 2017 Mar 8;7:44172
A 3 base pair deletion in TBX1 leads to reduced protein expression and transcriptional activity.
Xu Y, Fang S, Zhang E, Pu T, Cao R, Fu Q, Li F, Chen S, Sun K, Xu R
Scientific reports 2017 Mar 8;7:44165
Scientific reports 2017 Mar 8;7:44165
Neuroprotective effects of lycopene in spinal cord injury in rats via antioxidative and anti-apoptotic pathway.
Hu W, Wang H, Liu Z, Liu Y, Wang R, Luo X, Huang Y
Neuroscience letters 2017 Mar 6;642:107-112
Neuroscience letters 2017 Mar 6;642:107-112
Dectin-2 Deficiency Modulates Th1 Differentiation and Improves Wound Healing After Myocardial Infarction.
Yan X, Zhang H, Fan Q, Hu J, Tao R, Chen Q, Iwakura Y, Shen W, Lu L, Zhang Q, Zhang R
Circulation research 2017 Mar 31;120(7):1116-1129
Circulation research 2017 Mar 31;120(7):1116-1129
Transducin (β)-like 1 X-linked receptor 1 promotes gastric cancer progression via the ERK1/2 pathway.
Zhou Q, Wang X, Yu Z, Wu X, Chen X, Li J, Zhu Z, Liu B, Su L
Oncogene 2017 Mar 30;36(13):1873-1886
Oncogene 2017 Mar 30;36(13):1873-1886
IL-6 secreted by cancer-associated fibroblasts promotes epithelial-mesenchymal transition and metastasis of gastric cancer via JAK2/STAT3 signaling pathway.
Wu X, Tao P, Zhou Q, Li J, Yu Z, Wang X, Li J, Li C, Yan M, Zhu Z, Liu B, Su L
Oncotarget 2017 Mar 28;8(13):20741-20750
Oncotarget 2017 Mar 28;8(13):20741-20750
Nuclear localization of Beclin 1 promotes radiation-induced DNA damage repair independent of autophagy.
Xu F, Fang Y, Yan L, Xu L, Zhang S, Cao Y, Xu L, Zhang X, Xie J, Jiang G, Ge C, An N, Zhou D, Yuan N, Wang J
Scientific reports 2017 Mar 27;7:45385
Scientific reports 2017 Mar 27;7:45385
Anti-tumor effect of evodiamine by inducing Akt-mediated apoptosis in hepatocellular carcinoma.
Yang F, Shi L, Liang T, Ji L, Zhang G, Shen Y, Zhu F, Xu L
Biochemical and biophysical research communications 2017 Mar 25;485(1):54-61
Biochemical and biophysical research communications 2017 Mar 25;485(1):54-61
PPARβ/δ, a Novel Regulator for Vascular Smooth Muscle Cells Phenotypic Modulation and Vascular Remodeling after Subarachnoid Hemorrhage in Rats.
Zhang H, Jiang L, Guo Z, Zhong J, Wu J, He J, Liu H, He Z, Wu H, Cheng C, Sun X
Scientific reports 2017 Mar 22;7:45234
Scientific reports 2017 Mar 22;7:45234
Molecular signaling underlying bulleyaconitine A (BAA)-induced microglial expression of prodynorphin.
Li TF, Wu HY, Wang YR, Li XY, Wang YX
Scientific reports 2017 Mar 22;7:45056
Scientific reports 2017 Mar 22;7:45056
Whole-exome sequencing identified a homozygous BRDT mutation in a patient with acephalic spermatozoa.
Li L, Sha Y, Wang X, Li P, Wang J, Kee K, Wang B
Oncotarget 2017 Mar 21;8(12):19914-19922
Oncotarget 2017 Mar 21;8(12):19914-19922
The promotion of the transformation of quiescent gastric cancer stem cells by IL-17 and the underlying mechanisms.
Jiang YX, Yang SW, Li PA, Luo X, Li ZY, Hao YX, Yu PW
Oncogene 2017 Mar 2;36(9):1256-1264
Oncogene 2017 Mar 2;36(9):1256-1264
Combined transplantation of human mesenchymal stem cells and human retinal progenitor cells into the subretinal space of RCS rats.
Qu L, Gao L, Xu H, Duan P, Zeng Y, Liu Y, Yin ZQ
Scientific reports 2017 Mar 15;7(1):199
Scientific reports 2017 Mar 15;7(1):199
Cytoskeleton-associated protein 5 and clathrin heavy chain binding regulates spindle assembly in mouse oocytes.
Lu A, Zhou CJ, Wang DH, Han Z, Kong XW, Ma YZ, Yun ZZ, Liang CG
Oncotarget 2017 Mar 14;8(11):17491-17503
Oncotarget 2017 Mar 14;8(11):17491-17503
Nonstructural Protein 4 of Porcine Reproductive and Respiratory Syndrome Virus Modulates Cell Surface Swine Leukocyte Antigen Class I Expression by Downregulating β2-Microglobulin Transcription.
Qi P, Liu K, Wei J, Li Y, Li B, Shao D, Wu Z, Shi Y, Tong G, Qiu Y, Ma Z
Journal of virology 2017 Mar 1;91(5)
Journal of virology 2017 Mar 1;91(5)
Selenomethionine Mitigates Cognitive Decline by Targeting Both Tau Hyperphosphorylation and Autophagic Clearance in an Alzheimer's Disease Mouse Model.
Zhang ZH, Wu QY, Zheng R, Chen C, Chen Y, Liu Q, Hoffmann PR, Ni JZ, Song GL
The Journal of neuroscience : the official journal of the Society for Neuroscience 2017 Mar 1;37(9):2449-2462
The Journal of neuroscience : the official journal of the Society for Neuroscience 2017 Mar 1;37(9):2449-2462
The MLKL Channel in Necroptosis Is an Octamer Formed by Tetramers in a Dyadic Process.
Huang D, Zheng X, Wang ZA, Chen X, He WT, Zhang Y, Xu JG, Zhao H, Shi W, Wang X, Zhu Y, Han J
Molecular and cellular biology 2017 Mar 1;37(5)
Molecular and cellular biology 2017 Mar 1;37(5)
miR-137 downregulates c-kit expression in acute myeloid leukemia.
Hu Y, Dong X, Chu G, Lai G, Zhang B, Wang L, Zhao Y
Leukemia research 2017 Jun;57:72-77
Leukemia research 2017 Jun;57:72-77
miR-19 targeting of GSK3β mediates sulforaphane suppression of lung cancer stem cells.
Zhu J, Wang S, Chen Y, Li X, Jiang Y, Yang X, Li Y, Wang X, Meng Y, Zhu M, Ma X, Huang C, Wu R, Xie C, Geng S, Wu J, Zhong C, Han H
The Journal of nutritional biochemistry 2017 Jun;44:80-91
The Journal of nutritional biochemistry 2017 Jun;44:80-91
Cr(VI) induces cytotoxicity in vitro through activation of ROS-mediated endoplasmic reticulum stress and mitochondrial dysfunction via the PI3K/Akt signaling pathway.
Zhang Y, Xiao F, Liu X, Liu K, Zhou X, Zhong C
Toxicology in vitro : an international journal published in association with BIBRA 2017 Jun;41:232-244
Toxicology in vitro : an international journal published in association with BIBRA 2017 Jun;41:232-244
Simvastatin Inhibits IL-1β-Induced Apoptosis and Extracellular Matrix Degradation by Suppressing the NF-kB and MAPK Pathways in Nucleus Pulposus Cells.
Tu J, Li W, Zhang Y, Wu X, Song Y, Kang L, Liu W, Wang K, Li S, Hua W, Yang C
Inflammation 2017 Jun;40(3):725-734
Inflammation 2017 Jun;40(3):725-734
Apobec-1 complementation factor regulates cell migration and apoptosis through Dickkopf1 by acting on its 3' untranslated region in MCF7 cells.
Yan X, Li Q, Ni D, Xie Y, He Q, Wan Q, Liu Y, Lyu Z, Mao Z, Zhou Q
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2017 Jun;39(6):1010428317706218
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2017 Jun;39(6):1010428317706218
RON and c-Met facilitate metastasis through the ERK signaling pathway in prostate cancer cells.
Yin B, Liu Z, Wang Y, Wang X, Liu W, Yu P, Duan X, Liu C, Chen Y, Zhang Y, Pan X, Yao H, Liao Z, Tao Z
Oncology reports 2017 Jun;37(6):3209-3218
Oncology reports 2017 Jun;37(6):3209-3218
Cooperation of Musashi-2, Numb, MDM2, and P53 in drug resistance and malignant biology of pancreatic cancer.
Sheng W, Dong M, Chen C, Wang Z, Li Y, Wang K, Li Y, Zhou J
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2017 Jun;31(6):2429-2438
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2017 Jun;31(6):2429-2438
Role of the Wnt/β-catenin signaling pathway in inducing apoptosis and renal fibrosis in 5/6-nephrectomized rats.
Lin X, Zha Y, Zeng XZ, Dong R, Wang QH, Wang DT
Molecular medicine reports 2017 Jun;15(6):3575-3582
Molecular medicine reports 2017 Jun;15(6):3575-3582
Overexpressed miR-9 promotes tumor metastasis via targeting E-cadherin in serous ovarian cancer.
Zhou B, Xu H, Xia M, Sun C, Li N, Guo E, Guo L, Shan W, Lu H, Wu Y, Li Y, Yang D, Weng D, Meng L, Hu J, Ma D, Chen G, Li K
Frontiers of medicine 2017 Jun;11(2):214-222
Frontiers of medicine 2017 Jun;11(2):214-222
Nucleotide-binding oligomerization domain (NOD) signaling defects and cell death susceptibility cannot be uncoupled in X-linked inhibitor of apoptosis (XIAP)-driven inflammatory disease.
Chirieleison SM, Marsh RA, Kumar P, Rathkey JK, Dubyak GR, Abbott DW
The Journal of biological chemistry 2017 Jun 9;292(23):9666-9679
The Journal of biological chemistry 2017 Jun 9;292(23):9666-9679
Loss of the novel mitochondrial protein FAM210B promotes metastasis via PDK4-dependent metabolic reprogramming.
Sun S, Liu J, Zhao M, Han Y, Chen P, Mo Q, Wang B, Chen G, Fang Y, Tian Y, Zhou J, Ma D, Gao Q, Wu P
Cell death & disease 2017 Jun 8;8(6):e2870
Cell death & disease 2017 Jun 8;8(6):e2870
Upconversion nanoparticle-mediated photodynamic therapy induces autophagy and cholesterol efflux of macrophage-derived foam cells via ROS generation.
Han XB, Li HX, Jiang YQ, Wang H, Li XS, Kou JY, Zheng YH, Liu ZN, Li H, Li J, Dou D, Wang Y, Tian Y, Yang LM
Cell death & disease 2017 Jun 8;8(6):e2864
Cell death & disease 2017 Jun 8;8(6):e2864
Erythropoietin activates SIRT1 to protect human cardiomyocytes against doxorubicin-induced mitochondrial dysfunction and toxicity.
Cui L, Guo J, Zhang Q, Yin J, Li J, Zhou W, Zhang T, Yuan H, Zhao J, Zhang L, Carmichael PL, Peng S
Toxicology letters 2017 Jun 5;275:28-38
Toxicology letters 2017 Jun 5;275:28-38
(-)-Epigallocatechin-3-Gallate Inhibits Colorectal Cancer Stem Cells by Suppressing Wnt/β-Catenin Pathway.
Chen Y, Wang XQ, Zhang Q, Zhu JY, Li Y, Xie CF, Li XT, Wu JS, Geng SS, Zhong CY, Han HY
Nutrients 2017 Jun 3;9(6)
Nutrients 2017 Jun 3;9(6)
miR-181d/MALT1 regulatory axis attenuates mesenchymal phenotype through NF-κB pathways in glioblastoma.
Yang F, Liu X, Liu Y, Liu Y, Zhang C, Wang Z, Jiang T, Wang Y
Cancer letters 2017 Jun 28;396:1-9
Cancer letters 2017 Jun 28;396:1-9
AQP9-induced cell cycle arrest is associated with RAS activation and improves chemotherapy treatment efficacy in colorectal cancer.
Huang D, Feng X, Liu Y, Deng Y, Chen H, Chen D, Fang L, Cai Y, Liu H, Wang L, Wang J, Yang Z
Cell death & disease 2017 Jun 22;8(6):e2894
Cell death & disease 2017 Jun 22;8(6):e2894
Total Flavonoids of Drynariae Rhizoma Prevent Bone Loss Induced by Hindlimb Unloading in Rats.
Song S, Gao Z, Lei X, Niu Y, Zhang Y, Li C, Lu Y, Wang Z, Shang P
Molecules (Basel, Switzerland) 2017 Jun 22;22(7)
Molecules (Basel, Switzerland) 2017 Jun 22;22(7)
Chemokine receptor CXCR4 regulates CaMKII/CREB pathway in spinal neurons that underlies cancer-induced bone pain.
Hu XM, Zhang H, Xu H, Zhang HL, Chen LP, Cui WQ, Yang W, Shen W
Scientific reports 2017 Jun 21;7(1):4005
Scientific reports 2017 Jun 21;7(1):4005
Long-Term Dietary Supplementation with Selenium-Enriched Yeast Improves Cognitive Impairment, Reverses Synaptic Deficits, and Mitigates Tau Pathology in a Triple Transgenic Mouse Model of Alzheimer's Disease.
Zhang ZH, Wen L, Wu QY, Chen C, Zheng R, Liu Q, Ni JZ, Song GL
Journal of agricultural and food chemistry 2017 Jun 21;65(24):4970-4979
Journal of agricultural and food chemistry 2017 Jun 21;65(24):4970-4979
Expression of estrogen receptors and androgen receptor and their clinical significance in gastric cancer.
Tang W, Liu R, Yan Y, Pan X, Wang M, Han X, Ren H, Zhang Z
Oncotarget 2017 Jun 20;8(25):40765-40777
Oncotarget 2017 Jun 20;8(25):40765-40777
Clonorchis sinensis lysophospholipase A upregulates IL-25 expression in macrophages as a potential pathway to liver fibrosis.
Zhou L, Shi M, Zhao L, Lin Z, Tang Z, Sun H, Chen T, Lv Z, Xu J, Huang Y, Yu X
Parasites & vectors 2017 Jun 17;10(1):295
Parasites & vectors 2017 Jun 17;10(1):295
RUFY3 interaction with FOXK1 promotes invasion and metastasis in colorectal cancer.
Xie R, Wang J, Liu X, Wu L, Zhang H, Tang W, Li Y, Xiang L, Peng Y, Huang X, Bai Y, Liu G, Li A, Wang Y, Chen Y, Ren Y, Li G, Gong W, Liu S, Wang J
Scientific reports 2017 Jun 16;7(1):3709
Scientific reports 2017 Jun 16;7(1):3709
CDK4 protein is degraded by anaphase-promoting complex/cyclosome in mitosis and reaccumulates in early G(1) phase to initiate a new cell cycle in HeLa cells.
Chen H, Xu X, Wang G, Zhang B, Wang G, Xin G, Liu J, Jiang Q, Zhang H, Zhang C
The Journal of biological chemistry 2017 Jun 16;292(24):10131-10141
The Journal of biological chemistry 2017 Jun 16;292(24):10131-10141
Quantitative Proteomic Analysis of Mosquito C6/36 Cells Reveals Host Proteins Involved in Zika Virus Infection.
Xin QL, Deng CL, Chen X, Wang J, Wang SB, Wang W, Deng F, Zhang B, Xiao G, Zhang LK
Journal of virology 2017 Jun 15;91(12)
Journal of virology 2017 Jun 15;91(12)
BST2 confers cisplatin resistance via NF-κB signaling in nasopharyngeal cancer.
Kuang CM, Fu X, Hua YJ, Shuai WD, Ye ZH, Li Y, Peng QH, Li YZ, Chen S, Qian CN, Huang W, Liu RY
Cell death & disease 2017 Jun 15;8(6):e2874
Cell death & disease 2017 Jun 15;8(6):e2874
The phosphatase Pgam5 antagonizes Wnt/β-Catenin signaling in embryonic anterior-posterior axis patterning.
Rauschenberger V, Bernkopf DB, Krenn S, Jalal K, Heller J, Behrens J, Gentzel M, Schambony A
Development (Cambridge, England) 2017 Jun 15;144(12):2234-2247
Development (Cambridge, England) 2017 Jun 15;144(12):2234-2247
Promoting tumorigenesis in nasopharyngeal carcinoma, NEDD8 serves as a potential theranostic target.
Xie P, Yang JP, Cao Y, Peng LX, Zheng LS, Sun R, Meng DF, Wang MY, Mei Y, Qiang YY, Cao L, Xiang YQ, Luo DH, Yun JP, Huang BJ, Jia LJ, Qian CN
Cell death & disease 2017 Jun 1;8(6):e2834
Cell death & disease 2017 Jun 1;8(6):e2834
cMyBP-C was decreased via KLHL3-mediated proteasomal degradation in congenital heart diseases.
Wang L, Lai G, Chu G, Liang X, Zhao Y
Experimental cell research 2017 Jun 1;355(1):18-25
Experimental cell research 2017 Jun 1;355(1):18-25
Autocrine Prolactin Stimulates Endometrial Carcinoma Growth and Metastasis and Reduces Sensitivity to Chemotherapy.
Ding K, Yuan Y, Chong QY, Yang Y, Li R, Li X, Kong X, Qian P, Xiong Z, Pandey V, Ma L, Wu Z, Lobie PE, Zhu T
Endocrinology 2017 Jun 1;158(6):1595-1611
Endocrinology 2017 Jun 1;158(6):1595-1611
Wogonin mitigates nonalcoholic fatty liver disease via enhancing PPARα/AdipoR2, in vivo and in vitro.
Chen J, Liu J, Wang Y, Hu X, Zhou F, Hu Y, Yuan Y, Xu Y
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2017 Jul;91:621-631
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2017 Jul;91:621-631
Garlic-derived organosulfur compound exerts antitumor efficacy via activation of MAPK pathway and modulation of cytokines in SGC-7901 tumor-bearing mice.
Jiang X, Zhu X, Huang W, Xu H, Zhao Z, Li S, Li S, Cai J, Cao J
International immunopharmacology 2017 Jul;48:135-145
International immunopharmacology 2017 Jul;48:135-145
Timing of autophagy and apoptosis during posterior silk gland degeneration in Bombyx mori.
Montali A, Romanelli D, Cappellozza S, Grimaldi A, de Eguileor M, Tettamanti G
Arthropod structure & development 2017 Jul;46(4):518-528
Arthropod structure & development 2017 Jul;46(4):518-528
RUVBL1-ITFG1 interaction is required for collective invasion in breast cancer.
Fan W, Xie J, Xia J, Zhang Y, Yang M, Wang H, Pan Y, Zhang M, Han B, Wu B, Hou Z, Liang D, Wang C, Xu J, Song L, Liu Q
Biochimica et biophysica acta. General subjects 2017 Jul;1861(7):1788-1800
Biochimica et biophysica acta. General subjects 2017 Jul;1861(7):1788-1800
Correlation study of DNA methylation of WNT6 gene with osteosarcoma in children.
Li L, Xu C, Liu P, Huang J
Oncology letters 2017 Jul;14(1):271-275
Oncology letters 2017 Jul;14(1):271-275
Bacterial effector NleL promotes enterohemorrhagic E. coli-induced attaching and effacing lesions by ubiquitylating and inactivating JNK.
Sheng X, You Q, Zhu H, Chang Z, Li Q, Wang H, Wang C, Wang H, Hui L, Du C, Xie X, Zeng R, Lin A, Shi D, Ruan K, Yan J, Gao GF, Shao F, Hu R
PLoS pathogens 2017 Jul;13(7):e1006534
PLoS pathogens 2017 Jul;13(7):e1006534
USP19 suppresses cellular type I interferon signaling by targeting TRAF3 for deubiquitination.
Gu Z, Shi W, Zhang L, Hu Z, Xu C
Future microbiology 2017 Jul;12:767-779
Future microbiology 2017 Jul;12:767-779
Cigarette smoke extract induces EGFR-TKI resistance via promoting EGFR signaling pathway and ROS generation in NSCLC cell lines.
Zhang L, Li J, Hu J, Li D, Wang X, Zhang R, Zhang H, Shi M, Chen H
Lung cancer (Amsterdam, Netherlands) 2017 Jul;109:109-116
Lung cancer (Amsterdam, Netherlands) 2017 Jul;109:109-116
5T4-specific chimeric antigen receptor modification promotes the immune efficacy of cytokine-induced killer cells against nasopharyngeal carcinoma stem cell-like cells.
Guo X, Zheng H, Luo W, Zhang Q, Liu J, Yao K
Scientific reports 2017 Jul 7;7(1):4859
Scientific reports 2017 Jul 7;7(1):4859
SNORD47, a box C/D snoRNA, suppresses tumorigenesis in glioblastoma.
Xu B, Ye MH, Lv SG, Wang QX, Wu MJ, Xiao B, Kang CS, Zhu XG
Oncotarget 2017 Jul 4;8(27):43953-43966
Oncotarget 2017 Jul 4;8(27):43953-43966
Down-regulation of UBC9 increases the sensitivity of hepatocellular carcinoma to doxorubicin.
Fang S, Qiu J, Wu Z, Bai T, Guo W
Oncotarget 2017 Jul 25;8(30):49783-49795
Oncotarget 2017 Jul 25;8(30):49783-49795
Fork Head Box Class O1 (FOXO1) Activates Bim Expression to Mediate Cardiac Apoptosis in Chronic Intermittent Hypoxia-Induced Cardiac Hypertrophy.
Li G, Jin M, He Y, Ren J, Zhang M, Chen Y, Lan X, Zhong J, Liu H
Medical science monitor : international medical journal of experimental and clinical research 2017 Jul 24;23:3603-3616
Medical science monitor : international medical journal of experimental and clinical research 2017 Jul 24;23:3603-3616
Correction: Phosphoglycerate mutase 1 regulates dNTP pool and promotes homologous recombination repair in cancer cells.
Qu J, Sun W, Zhong J, Lv H, Zhu M, Xu J, Jin N, Xie Z, Tan M, Lin SH, Geng M, Ding J, Huang M
The Journal of cell biology 2017 Jul 24;216(8):2597-8
The Journal of cell biology 2017 Jul 24;216(8):2597-8
Autophagosome maturation mediated by Rab7 contributes to neuroprotection of hypoxic preconditioning against global cerebral ischemia in rats.
Zhan L, Chen S, Li K, Liang D, Zhu X, Liu L, Lu Z, Sun W, Xu E
Cell death & disease 2017 Jul 20;8(7):e2949
Cell death & disease 2017 Jul 20;8(7):e2949
FOXQ1 regulates senescence-associated inflammation via activation of SIRT1 expression.
Wang P, Lv C, Zhang T, Liu J, Yang J, Guan F, Hong T
Cell death & disease 2017 Jul 20;8(7):e2946
Cell death & disease 2017 Jul 20;8(7):e2946
KMT2A promotes melanoma cell growth by targeting hTERT signaling pathway.
Zhang C, Song C, Liu T, Tang R, Chen M, Gao F, Xiao B, Qin G, Shi F, Li W, Li Y, Fu X, Shi D, Xiao X, Kang L, Huang W, Wu X, Tang B, Deng W
Cell death & disease 2017 Jul 20;8(7):e2940
Cell death & disease 2017 Jul 20;8(7):e2940
A hydrophobic residue in the TALE homeodomain of PBX1 promotes epithelial-to-mesenchymal transition of gastric carcinoma.
He C, Wang Z, Zhang L, Yang L, Li J, Chen X, Zhang J, Chang Q, Yu Y, Liu B, Zhu Z
Oncotarget 2017 Jul 18;8(29):46818-46833
Oncotarget 2017 Jul 18;8(29):46818-46833
Novel function of pregnancy-associated plasma protein A: promotes endometrium receptivity by up-regulating N-fucosylation.
Yu M, Wang J, Liu S, Wang X, Yan Q
Scientific reports 2017 Jul 13;7(1):5315
Scientific reports 2017 Jul 13;7(1):5315
Hydrogen sulfide attenuates cardiac injury in takotsubo cardiomyopathy by alleviating oxidative stress.
Zhang Z, Jin S, Teng X, Duan X, Chen Y, Wu Y
Nitric oxide : biology and chemistry 2017 Jul 1;67:10-25
Nitric oxide : biology and chemistry 2017 Jul 1;67:10-25
Feeding influences adipose tissue responses to exercise in overweight men.
Chen YC, Travers RL, Walhin JP, Gonzalez JT, Koumanov F, Betts JA, Thompson D
American journal of physiology. Endocrinology and metabolism 2017 Jul 1;313(1):E84-E93
American journal of physiology. Endocrinology and metabolism 2017 Jul 1;313(1):E84-E93
Resveratrol Pretreatment Decreases Ischemic Injury and Improves Neurological Function Via Sonic Hedgehog Signaling After Stroke in Rats.
Yu P, Wang L, Tang F, Zeng L, Zhou L, Song X, Jia W, Chen J, Yang Q
Molecular neurobiology 2017 Jan;54(1):212-226
Molecular neurobiology 2017 Jan;54(1):212-226
H/ACA Box Small Nucleolar RNA 7A Promotes the Self-Renewal of Human Umbilical Cord Mesenchymal Stem Cells.
Zhang Y, Xu C, Gu D, Wu M, Yan B, Xu Z, Wang Y, Liu H
Stem cells (Dayton, Ohio) 2017 Jan;35(1):222-235
Stem cells (Dayton, Ohio) 2017 Jan;35(1):222-235
Runx2, a novel regulator for goblet cell differentiation and asthma development.
Shi N, Zhang J, Chen SY
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2017 Jan;31(1):412-420
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2017 Jan;31(1):412-420
Cigarette smoke extract-induced proliferation of normal human urothelial cells via the MAPK/AP-1 pathway.
Geng H, Zhao L, Liang Z, Zhang Z, Xie D, Bi L, Wang Y, Zhang T, Cheng L, Yu D, Zhong C
Oncology letters 2017 Jan;13(1):469-475
Oncology letters 2017 Jan;13(1):469-475
Anti-inflammatory and neuroprotective effects of sanguinarine following cerebral ischemia in rats.
Wang Q, Dai P, Bao H, Liang P, Wang W, Xing A, Sun J
Experimental and therapeutic medicine 2017 Jan;13(1):263-268
Experimental and therapeutic medicine 2017 Jan;13(1):263-268
Forkhead box P3 regulates ARHGAP15 expression and affects migration of glioma cells through the Rac1 signaling pathway.
Sun Z, Zhang B, Wang C, Fu T, Li L, Wu Q, Cai Y, Wang J
Cancer science 2017 Jan;108(1):61-72
Cancer science 2017 Jan;108(1):61-72
Long-term exposure to a 'safe' dose of bisphenol A reduced protein acetylation in adult rat testes.
Chen Z, Zuo X, He D, Ding S, Xu F, Yang H, Jin X, Fan Y, Ying L, Tian C, Ying C
Scientific reports 2017 Jan 9;7:40337
Scientific reports 2017 Jan 9;7:40337
Mitomycin C-treated human-induced pluripotent stem cells as a safe delivery system of gold nanorods for targeted photothermal therapy of gastric cancer.
Yang M, Liu Y, Hou W, Zhi X, Zhang C, Jiang X, Pan F, Yang Y, Ni J, Cui D
Nanoscale 2017 Jan 7;9(1):334-340
Nanoscale 2017 Jan 7;9(1):334-340
Identification of a novel missense mutation of MIP in a Chinese family with congenital cataracts by target region capture sequencing.
Jiang B, Chen Y, Xu B, Hong N, Liu R, Qi M, Shen L
Scientific reports 2017 Jan 6;7:40129
Scientific reports 2017 Jan 6;7:40129
The RhoA/ROCK Pathway Ameliorates Adhesion and Inflammatory Infiltration Induced by AGEs in Glomerular Endothelial Cells.
Rao J, Ye Z, Tang H, Wang C, Peng H, Lai W, Li Y, Huang W, Lou T
Scientific reports 2017 Jan 5;7:39727
Scientific reports 2017 Jan 5;7:39727
Endothelial microparticles are increased in congenital heart diseases and contribute to endothelial dysfunction.
Lin ZB, Ci HB, Li Y, Cheng TP, Liu DH, Wang YS, Xu J, Yuan HX, Li HM, Chen J, Zhou L, Wang ZP, Zhang X, Ou ZJ, Ou JS
Journal of translational medicine 2017 Jan 4;15(1):4
Journal of translational medicine 2017 Jan 4;15(1):4
Genetic and epigenetic silencing of mircoRNA-506-3p enhances COTL1 oncogene expression to foster non-small lung cancer progression.
Guo S, Yang P, Jiang X, Li X, Wang Y, Zhang X, Sun B, Zhang Y, Jia Y
Oncotarget 2017 Jan 3;8(1):644-657
Oncotarget 2017 Jan 3;8(1):644-657
Metformin Induces Growth Inhibition and Cell Cycle Arrest by Upregulating MicroRNA34a in Renal Cancer Cells.
Xie W, Wang L, Sheng H, Qiu J, Zhang D, Zhang L, Yang F, Tang D, Zhang K
Medical science monitor : international medical journal of experimental and clinical research 2017 Jan 3;23:29-37
Medical science monitor : international medical journal of experimental and clinical research 2017 Jan 3;23:29-37
DAZ-interacting Protein 1 (Dzip1) Phosphorylation by Polo-like Kinase 1 (Plk1) Regulates the Centriolar Satellite Localization of the BBSome Protein during the Cell Cycle.
Zhang B, Wang G, Xu X, Yang S, Zhuang T, Wang G, Ren H, Cheng SY, Jiang Q, Zhang C
The Journal of biological chemistry 2017 Jan 27;292(4):1351-1360
The Journal of biological chemistry 2017 Jan 27;292(4):1351-1360
Resveratrol reverses Doxorubicin resistance by inhibiting epithelial-mesenchymal transition (EMT) through modulating PTEN/Akt signaling pathway in gastric cancer.
Xu J, Liu D, Niu H, Zhu G, Xu Y, Ye D, Li J, Zhang Q
Journal of experimental & clinical cancer research : CR 2017 Jan 26;36(1):19
Journal of experimental & clinical cancer research : CR 2017 Jan 26;36(1):19
Hormetic effect of panaxatriol saponins confers neuroprotection in PC12 cells and zebrafish through PI3K/AKT/mTOR and AMPK/SIRT1/FOXO3 pathways.
Zhang C, Li C, Chen S, Li Z, Ma L, Jia X, Wang K, Bao J, Liang Y, Chen M, Li P, Su H, Lee SM, Liu K, Wan JB, He C
Scientific reports 2017 Jan 23;7:41082
Scientific reports 2017 Jan 23;7:41082
Up-regulation of syncytin-1 contributes to TNF-α-enhanced fusion between OSCC and HUVECs partly via Wnt/β-catenin-dependent pathway.
Yan TL, Wang M, Xu Z, Huang CM, Zhou XC, Jiang EH, Zhao XP, Song Y, Song K, Shao Z, Liu K, Shang ZJ
Scientific reports 2017 Jan 23;7:40983
Scientific reports 2017 Jan 23;7:40983
B7-H3 regulates lipid metabolism of lung cancer through SREBP1-mediated expression of FASN.
Luo D, Xiao H, Dong J, Li Y, Feng G, Cui M, Fan S
Biochemical and biophysical research communications 2017 Jan 22;482(4):1246-1251
Biochemical and biophysical research communications 2017 Jan 22;482(4):1246-1251
Highly expressed lncRNA CCND2-AS1 promotes glioma cell proliferation through Wnt/β-catenin signaling.
Zhang H, Wei DL, Wan L, Yan SF, Sun YH
Biochemical and biophysical research communications 2017 Jan 22;482(4):1219-1225
Biochemical and biophysical research communications 2017 Jan 22;482(4):1219-1225
Secreted miR-27a Induced by Cyclic Stretch Modulates the Proliferation of Endothelial Cells in Hypertension via GRK6.
Wang L, Bao H, Wang KX, Zhang P, Yao QP, Chen XH, Huang K, Qi YX, Jiang ZL
Scientific reports 2017 Jan 20;7:41058
Scientific reports 2017 Jan 20;7:41058
Identification of TDP-43 as an oncogene in melanoma and its function during melanoma pathogenesis.
Zeng Q, Cao K, Liu R, Huang J, Xia K, Tang J, Chen X, Zhou M, Xie H, Zhou J
Cancer biology & therapy 2017 Jan 2;18(1):8-15
Cancer biology & therapy 2017 Jan 2;18(1):8-15
A comprehensive platform for the analysis of ubiquitin-like protein modifications using in vivo biotinylation.
Pirone L, Xolalpa W, Sigurðsson JO, Ramirez J, Pérez C, González M, de Sabando AR, Elortza F, Rodriguez MS, Mayor U, Olsen JV, Barrio R, Sutherland JD
Scientific reports 2017 Jan 18;7:40756
Scientific reports 2017 Jan 18;7:40756
Melatonin ameliorates amygdala-dependent emotional memory deficits in Tg2576 mice by up-regulating the CREB/c-Fos pathway.
Peng C, Hong X, Chen W, Zhang H, Tan L, Wang X, Ding Y, He J
Neuroscience letters 2017 Jan 18;638:76-82
Neuroscience letters 2017 Jan 18;638:76-82
[Changes of endogenous Spastin expression after sciatic nerve injury in rats].
Lin Y, Zong H, Hu X, Yu R, Shao W, Hou C, Lin H
Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery 2017 Jan 15;31(1):80-84
Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery 2017 Jan 15;31(1):80-84
Retromer- and WASH-dependent sorting of nutrient transporters requires a multivalent interaction network with ANKRD50.
Kvainickas A, Orgaz AJ, Nägele H, Diedrich B, Heesom KJ, Dengjel J, Cullen PJ, Steinberg F
Journal of cell science 2017 Jan 15;130(2):382-395
Journal of cell science 2017 Jan 15;130(2):382-395
Contractile forces at tricellular contacts modulate epithelial organization and monolayer integrity.
Salomon J, Gaston C, Magescas J, Duvauchelle B, Canioni D, Sengmanivong L, Mayeux A, Michaux G, Campeotto F, Lemale J, Viala J, Poirier F, Minc N, Schmitz J, Brousse N, Ladoux B, Goulet O, Delacour D
Nature communications 2017 Jan 13;8:13998
Nature communications 2017 Jan 13;8:13998
CRB3 regulates contact inhibition by activating the Hippo pathway in mammary epithelial cells.
Mao X, Li P, Wang Y, Liang Z, Liu J, Li J, Jiang Y, Bao G, Li L, Zhu B, Ren Y, Zhao X, Zhang J, Liu Y, Yang J, Liu P
Cell death & disease 2017 Jan 12;8(1):e2546
Cell death & disease 2017 Jan 12;8(1):e2546
TRIM52: A nuclear TRIM protein that positively regulates the nuclear factor-kappa B signaling pathway.
Fan W, Liu T, Li X, Zhou Y, Wu M, Cui X, Chen H, Qian P
Molecular immunology 2017 Feb;82:114-122
Molecular immunology 2017 Feb;82:114-122
MicroRNA-22 regulates inflammation and angiogenesis via targeting VE-cadherin.
Gu W, Zhan H, Zhou XY, Yao L, Yan M, Chen A, Liu J, Ren X, Zhang X, Liu JX, Liu G
FEBS letters 2017 Feb;591(3):513-526
FEBS letters 2017 Feb;591(3):513-526
Upregulation of miR-146a by YY1 depletion correlates with delayed progression of prostate cancer.
Huang Y, Tao T, Liu C, Guan H, Zhang G, Ling Z, Zhang L, Lu K, Chen S, Xu B, Chen M
International journal of oncology 2017 Feb;50(2):421-431
International journal of oncology 2017 Feb;50(2):421-431
MicroRNA-503-5p inhibits stretch-induced osteogenic differentiation and bone formation.
Liu L, Liu M, Li R, Liu H, Du L, Chen H, Zhang Y, Zhang S, Liu D
Cell biology international 2017 Feb;41(2):112-123
Cell biology international 2017 Feb;41(2):112-123
Expression of glia maturation factor γ is associated with colorectal cancer metastasis and its downregulation suppresses colorectal cancer cell migration and invasion in vitro.
Wang H, Chen Z, Chang H, Mu X, Deng W, Yuan Z, Yao F, Liu Y, Mai R, Wu B
Oncology reports 2017 Feb;37(2):929-936
Oncology reports 2017 Feb;37(2):929-936
Long Noncoding RNA DANCR Is a Positive Regulator of Proliferation and Chondrogenic Differentiation in Human Synovium-Derived Stem Cells.
Zhang L, Yang C, Chen S, Wang G, Shi B, Tao X, Zhou L, Zhao J
DNA and cell biology 2017 Feb;36(2):136-142
DNA and cell biology 2017 Feb;36(2):136-142
Diethylstilbestrol activates CatSper and disturbs progesterone actions in human spermatozoa.
Zou QX, Peng Z, Zhao Q, Chen HY, Cheng YM, Liu Q, He YQ, Weng SQ, Wang HF, Wang T, Zheng LP, Luo T
Human reproduction (Oxford, England) 2017 Feb;32(2):290-298
Human reproduction (Oxford, England) 2017 Feb;32(2):290-298
Kukoamine A Prevents Radiation-Induced Neuroinflammation and Preserves Hippocampal Neurogenesis in Rats by Inhibiting Activation of NF-κB and AP-1.
Zhang Y, Gao L, Cheng Z, Cai J, Niu Y, Meng W, Zhao Q
Neurotoxicity research 2017 Feb;31(2):259-268
Neurotoxicity research 2017 Feb;31(2):259-268
Phosphoglycerate mutase 1 regulates dNTP pool and promotes homologous recombination repair in cancer cells.
Qu J, Sun W, Zhong J, Lv H, Zhu M, Xu J, Jin N, Xie Z, Tan M, Lin SH, Geng M, Ding J, Huang M
The Journal of cell biology 2017 Feb;216(2):409-424
The Journal of cell biology 2017 Feb;216(2):409-424
The effect of nuclear factor erythroid 2-related factor/antioxidant response element signalling pathway in the lanthanum chloride-induced impairment of learning and memory in rats.
Zhang L, Yang J, Jin C, Wu S, Lu X, Hu X, Sun Y, Cai Y
Journal of neurochemistry 2017 Feb;140(3):463-475
Journal of neurochemistry 2017 Feb;140(3):463-475
GAPDH-mediated posttranscriptional regulations of sodium channel Scn1a and Scn3a genes under seizure and ketogenic diet conditions.
Lin GW, Lu P, Zeng T, Tang HL, Chen YH, Liu SJ, Gao MM, Zhao QH, Yi YH, Long YS
Neuropharmacology 2017 Feb;113(Pt A):480-489
Neuropharmacology 2017 Feb;113(Pt A):480-489
Triggering of apoptosis in osteosarcoma cells by graphene/single-walled carbon nanotube hybrids via the ROS-mediated mitochondrial pathway.
Yan X, Yang W, Shao Z, Yang S, Liu X
Journal of biomedical materials research. Part A 2017 Feb;105(2):443-453
Journal of biomedical materials research. Part A 2017 Feb;105(2):443-453
Quercetin induces autophagy via FOXO1-dependent pathways and autophagy suppression enhances quercetin-induced apoptosis in PASMCs in hypoxia.
He Y, Cao X, Guo P, Li X, Shang H, Liu J, Xie M, Xu Y, Liu X
Free radical biology & medicine 2017 Feb;103:165-176
Free radical biology & medicine 2017 Feb;103:165-176
Up-Regulation of RFC3 Promotes Triple Negative Breast Cancer Metastasis and is Associated With Poor Prognosis Via EMT.
He ZY, Wu SG, Peng F, Zhang Q, Luo Y, Chen M, Bao Y
Translational oncology 2017 Feb;10(1):1-9
Translational oncology 2017 Feb;10(1):1-9
LncRNA AK023948 is a positive regulator of AKT.
Koirala P, Huang J, Ho TT, Wu F, Ding X, Mo YY
Nature communications 2017 Feb 8;8:14422
Nature communications 2017 Feb 8;8:14422
Decreased expression of STING predicts poor prognosis in patients with gastric cancer.
Song S, Peng P, Tang Z, Zhao J, Wu W, Li H, Shao M, Li L, Yang C, Duan F, Zhang M, Zhang J, Wu H, Li C, Wang X, Wang H, Ruan Y, Gu J
Scientific reports 2017 Feb 8;7:39858
Scientific reports 2017 Feb 8;7:39858
A novel peptide, 9R-P201, strongly inhibits the viability, proliferation and migration of liver cancer HepG2 cells and induces apoptosis by down-regulation of FoxM1 expression.
Bi Z, Liu W, Ding R, Wu Y, Dou R, Zhang W, Yuan X, Liu X, Xiong L, Guo Z, Mao C
European journal of pharmacology 2017 Feb 5;796:175-189
European journal of pharmacology 2017 Feb 5;796:175-189
Luteolin suppresses gastric cancer progression by reversing epithelial-mesenchymal transition via suppression of the Notch signaling pathway.
Zang MD, Hu L, Fan ZY, Wang HX, Zhu ZL, Cao S, Wu XY, Li JF, Su LP, Li C, Zhu ZG, Yan M, Liu BY
Journal of translational medicine 2017 Feb 27;15(1):52
Journal of translational medicine 2017 Feb 27;15(1):52
HnRNP-L mediates bladder cancer progression by inhibiting apoptotic signaling and enhancing MAPK signaling pathways.
Lv D, Wu H, Xing R, Shu F, Lei B, Lei C, Zhou X, Wan B, Yang Y, Zhong L, Mao X, Zou Y
Oncotarget 2017 Feb 21;8(8):13586-13599
Oncotarget 2017 Feb 21;8(8):13586-13599
Simvastatin suppresses the DNA replication licensing factor MCM7 and inhibits the growth of tamoxifen-resistant breast cancer cells.
Liang Z, Li W, Liu J, Li J, He F, Jiang Y, Yang L, Li P, Wang B, Wang Y, Ren Y, Yang J, Luo Z, Vaziri C, Liu P
Scientific reports 2017 Feb 2;7:41776
Scientific reports 2017 Feb 2;7:41776
Method for Dual Viral Vector Mediated CRISPR-Cas9 Gene Disruption in Primary Human Endothelial Cells.
Gong H, Liu M, Klomp J, Merrill BJ, Rehman J, Malik AB
Scientific reports 2017 Feb 15;7:42127
Scientific reports 2017 Feb 15;7:42127
RELM-β promotes human pulmonary artery smooth muscle cell proliferation via FAK-stimulated surviving.
Lin C, Li X, Luo Q, Yang H, Li L, Zhou Q, Li Y, Tang H, Wu L
Experimental cell research 2017 Feb 1;351(1):43-50
Experimental cell research 2017 Feb 1;351(1):43-50
Sinomenine hydrochloride attenuates the proliferation, migration, invasiveness, angiogenesis and epithelial-mesenchymal transition of clear-cell renal cell carcinoma cells via targeting Smad in vitro.
Zhao B, Liu L, Mao J, Liu K, Fan W, Liu J, Zhang Z, Li Q
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2017 Dec;96:1036-1044
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2017 Dec;96:1036-1044
Quantitative determination, principal component analysis and discriminant analysis of eight marker compounds in crude and sweated Dipsaci Radix by HPLC-DAD.
Du W, Li X, Yang Y, Yue X, Jiang D, Ge W, Cai B
Pharmaceutical biology 2017 Dec;55(1):2129-2135
Pharmaceutical biology 2017 Dec;55(1):2129-2135
Long non-coding RNA CASC15 is upregulated in hepatocellular carcinoma and facilitates hepatocarcinogenesis.
He T, Zhang L, Kong Y, Huang Y, Zhang Y, Zhou D, Zhou X, Yan Y, Zhang L, Lu S, Zhou J, Wang W
International journal of oncology 2017 Dec;51(6):1722-1730
International journal of oncology 2017 Dec;51(6):1722-1730
MTA-induced Notch activation enhances the proliferation of human dental pulp cells by inhibiting autophagic flux.
Qiu W, Sun B, He F, Zhang Y
International endodontic journal 2017 Dec;50 Suppl 2:e52-e62
International endodontic journal 2017 Dec;50 Suppl 2:e52-e62
Productive HBV infection of well-differentiated, hNTCP-expressing human hepatoma-derived (Huh7) cells.
Zhou M, Zhao K, Yao Y, Yuan Y, Pei R, Wang Y, Chen J, Hu X, Zhou Y, Chen X, Wu C
Virologica Sinica 2017 Dec;32(6):465-475
Virologica Sinica 2017 Dec;32(6):465-475
Glucose potentiates β-cell function by inducing Tph1 expression in rat islets.
Zhang Y, Deng R, Yang X, Xu W, Liu Y, Li F, Zhang J, Tang H, Ji X, Bi Y, Wang X, Zhou L, Ning G
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2017 Dec;31(12):5342-5355
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2017 Dec;31(12):5342-5355
MicroRNA-200c impairs uterine receptivity formation by targeting FUT4 and α1,3-fucosylation.
Zheng Q, Zhang D, Yang YU, Cui X, Sun J, Liang C, Qin H, Yang X, Liu S, Yan Q
Cell death and differentiation 2017 Dec;24(12):2161-2172
Cell death and differentiation 2017 Dec;24(12):2161-2172
MiR-616 promotes proliferation and inhibits apoptosis in glioma cells by suppressing expression of SOX7 via the Wnt signaling pathway.
Bai QL, Hu CW, Wang XR, Shang JX, Yin GF
European review for medical and pharmacological sciences 2017 Dec;21(24):5630-5637
European review for medical and pharmacological sciences 2017 Dec;21(24):5630-5637
Expression of PTEN-long mediated by CRISPR/Cas9 can repress U87 cell proliferation.
Fang N, Gu T, Wang Y, Wang S, Wang F, An Y, Wei W, Zhang W, Guo X, Nazarali AJ, Ji S
Journal of cellular and molecular medicine 2017 Dec;21(12):3337-3346
Journal of cellular and molecular medicine 2017 Dec;21(12):3337-3346
POSH participates in epileptogenesis by increasing the surface expression of the NMDA receptor: a promising therapeutic target for epilepsy.
Wang X, Tian X, Yang Y, Lu X, Li Y, Ma Y, Zhang Y, Zheng F, Lu S, Xu D, Xu X, Wang W, Wang X
Expert opinion on therapeutic targets 2017 Dec;21(12):1083-1094
Expert opinion on therapeutic targets 2017 Dec;21(12):1083-1094
The reproductive toxicology of male SD rats after PM(2.5) exposure mediated by the stimulation of endoplasmic reticulum stress.
Liu X, Jin X, Su R, Li Z
Chemosphere 2017 Dec;189:547-555
Chemosphere 2017 Dec;189:547-555
Autophagy is essential for flavopiridol‑induced cytotoxicity against MCF‑7 breast cancer cells.
Wang S, Wang K, Wang H, Han J, Sun H
Molecular medicine reports 2017 Dec;16(6):9715-9720
Molecular medicine reports 2017 Dec;16(6):9715-9720
20-Hydroxyeicosatetraenoic acid regulates the expression of Nedd4‑2 in kidney and liver through a neddylation modification pathway.
Zhao J, Zhang B, Lai G, Xu R, Chu G, Zhao Y
Molecular medicine reports 2017 Dec;16(6):9671-9677
Molecular medicine reports 2017 Dec;16(6):9671-9677
Baicalin alleviates H2O2‑induced injury of H9c2 cardiomyocytes through suppression of the Wnt/β‑catenin signaling pathway.
Qiu L, Chen J, Lin J, Wo D, Chu J, Peng J
Molecular medicine reports 2017 Dec;16(6):9251-9255
Molecular medicine reports 2017 Dec;16(6):9251-9255
Propofol regulates the expression of TLR4 through miR‑21 in human umbilical vein endothelial cells.
Ma L, Yang Y, Sun X, Jiang M, Ma Y, Yang X, Guo Z
Molecular medicine reports 2017 Dec;16(6):9074-9080
Molecular medicine reports 2017 Dec;16(6):9074-9080
EPAC-RAP1 Axis-Mediated Switch in the Response of Primary and Metastatic Melanoma to Cyclic AMP.
Rodríguez CI, Castro-Pérez E, Prabhakar K, Block L, Longley BJ, Wisinski JA, Kimple ME, Setaluri V
Molecular cancer research : MCR 2017 Dec;15(12):1792-1802
Molecular cancer research : MCR 2017 Dec;15(12):1792-1802
Molecular mechanisms in vascular injury induced by hypertension: Expression and role of microRNA-34a.
Liu S, Yi F, Cheng W, Qu X, Wang C
Experimental and therapeutic medicine 2017 Dec;14(6):5497-5502
Experimental and therapeutic medicine 2017 Dec;14(6):5497-5502
Alginate enhances Toll-like receptor 4-mediated phagocytosis by murine RAW264.7 macrophages.
Bi D, Zhou R, Cai N, Lai Q, Han Q, Peng Y, Jiang Z, Tang Z, Lu J, Bao W, Xu H, Xu X
International journal of biological macromolecules 2017 Dec;105(Pt 2):1446-1454
International journal of biological macromolecules 2017 Dec;105(Pt 2):1446-1454
Biologico-clinical significance of DNMT3A variants expression in acute myeloid leukemia.
Lin N, Fu W, Zhao C, Li B, Yan X, Li Y
Biochemical and biophysical research communications 2017 Dec 9;494(1-2):270-277
Biochemical and biophysical research communications 2017 Dec 9;494(1-2):270-277
Upregulation of miR-126-3p promotes human saphenous vein endothelial cell proliferation in vitro and prevents vein graft neointimal formation ex vivo and in vivo.
Qu Q, Bing W, Meng X, Xi J, Bai X, Liu Q, Guo Y, Zhao X, Bi Y
Oncotarget 2017 Dec 5;8(63):106790-106806
Oncotarget 2017 Dec 5;8(63):106790-106806
A novel KCND3 mutation associated with early-onset lone atrial fibrillation.
Huang Y, Yang J, Xie W, Li Q, Zeng Z, Sui H, Shan Z, Huang Z
Oncotarget 2017 Dec 29;8(70):115503-115512
Oncotarget 2017 Dec 29;8(70):115503-115512
EGFR expression in patients with stage III colorectal cancer after adjuvant chemotherapy and on cancer cell function.
Huang CW, Chen YT, Tsai HL, Yeh YS, Su WC, Ma CJ, Tsai TN, Wang JY
Oncotarget 2017 Dec 29;8(70):114663-114676
Oncotarget 2017 Dec 29;8(70):114663-114676
Respiratory Syncytial Virus Nonstructural Protein 1 Blocks Glucocorticoid Receptor Nuclear Translocation by Targeting IPO13 and May Account for Glucocorticoid Insensitivity.
Xie J, Long X, Gao L, Chen S, Zhao K, Li W, Zhou N, Zang N, Deng Y, Ren L, Wang L, Luo Z, Tu W, Zhao X, Fu Z, Xie X, Liu E
The Journal of infectious diseases 2017 Dec 27;217(1):35-46
The Journal of infectious diseases 2017 Dec 27;217(1):35-46
Interactions between GHRH and GABAARs in the brains of patients with epilepsy and in animal models of epilepsy.
Tang S, Luo Z, Qiu X, Zhang Y, Lu X, Huang H, Xu Z, Xu Z
Scientific reports 2017 Dec 22;7(1):18110
Scientific reports 2017 Dec 22;7(1):18110
Morin enhances hepatic Nrf2 expression in a liver fibrosis rat model.
Sang L, Wang XM, Xu DY, Sang LX, Han Y, Jiang LY
World journal of gastroenterology 2017 Dec 21;23(47):8334-8344
World journal of gastroenterology 2017 Dec 21;23(47):8334-8344
ICAM-1 regulates macrophage polarization by suppressing MCP-1 expression via miR-124 upregulation.
Gu W, Yao L, Li L, Zhang J, Place AT, Minshall RD, Liu G
Oncotarget 2017 Dec 19;8(67):111882-111901
Oncotarget 2017 Dec 19;8(67):111882-111901
Disruption of the c-Myc/miR-200b-3p/PRDX2 regulatory loop enhances tumor metastasis and chemotherapeutic resistance in colorectal cancer.
Lv Z, Wei J, You W, Wang R, Shang J, Xiong Y, Yang H, Yang X, Fu Z
Journal of translational medicine 2017 Dec 19;15(1):257
Journal of translational medicine 2017 Dec 19;15(1):257
Bifunctional enzyme ATIC promotes propagation of hepatocellular carcinoma by regulating AMPK-mTOR-S6 K1 signaling.
Li M, Jin C, Xu M, Zhou L, Li D, Yin Y
Cell communication and signaling : CCS 2017 Dec 16;15(1):52
Cell communication and signaling : CCS 2017 Dec 16;15(1):52
Mammalian Numb protein antagonizes Notch by controlling postendocytic trafficking of the Notch ligand Delta-like 4.
Shao X, Ding Z, Zhao M, Liu K, Sun H, Chen J, Liu X, Zhang Y, Hong Y, Li H, Li H
The Journal of biological chemistry 2017 Dec 15;292(50):20628-20643
The Journal of biological chemistry 2017 Dec 15;292(50):20628-20643
Interleukin-22 participates in the inflammatory process of vitiligo.
Dong J, An X, Zhong H, Wang Y, Shang J, Zhou J
Oncotarget 2017 Dec 12;8(65):109161-109174
Oncotarget 2017 Dec 12;8(65):109161-109174
HRD1 prevents apoptosis in renal tubular epithelial cells by mediating eIF2α ubiquitylation and degradation.
Huang Y, Sun Y, Cao Y, Sun H, Li M, You H, Su D, Li Y, Liang X
Cell death & disease 2017 Dec 11;8(12):3202
Cell death & disease 2017 Dec 11;8(12):3202
Human Cytomegalovirus Encoded miR-US25-1-5p Attenuates CD147/EMMPRIN-Mediated Early Antiviral Response.
Chen J, Xia S, Yang X, Chen H, Li F, Liu F, Chen Z
Viruses 2017 Dec 1;9(12)
Viruses 2017 Dec 1;9(12)
Bisphenol a induces autophagy and apoptosis concurrently involving the Akt/mTOR pathway in testes of pubertal SD rats.
Quan C, Wang C, Duan P, Huang W, Chen W, Tang S, Yang K
Environmental toxicology 2017 Aug;32(8):1977-1989
Environmental toxicology 2017 Aug;32(8):1977-1989
Looping-out mechanism for resolution of replicative stress at telomeres.
Zhang T, Zhang Z, Li F, Hu Q, Liu H, Tang M, Ma W, Huang J, Songyang Z, Rong Y, Zhang S, Chen BP, Zhao Y
EMBO reports 2017 Aug;18(8):1412-1428
EMBO reports 2017 Aug;18(8):1412-1428
MicroRNA-149 contributes to scarless wound healing by attenuating inflammatory response.
Lang H, Zhao F, Zhang T, Liu X, Wang Z, Wang R, Shi P, Pang X
Molecular medicine reports 2017 Aug;16(2):2156-2162
Molecular medicine reports 2017 Aug;16(2):2156-2162
Protective effect of lutein on ARPE-19 cells upon H2O2-induced G2/M arrest.
Liu H, Liu W, Zhou X, Long C, Kuang X, Hu J, Tang Y, Liu L, He J, Huang Z, Fan Y, Jin G, Zhang Q, Shen H
Molecular medicine reports 2017 Aug;16(2):2069-2074
Molecular medicine reports 2017 Aug;16(2):2069-2074
Intermedin improves cardiac function and sympathetic neural remodeling in a rat model of post myocardial infarction heart failure.
Xu B, Xu H, Cao H, Liu X, Qin C, Zhao Y, Han X, Li H
Molecular medicine reports 2017 Aug;16(2):1723-1730
Molecular medicine reports 2017 Aug;16(2):1723-1730
The effects of hyperoside on apoptosis and the expression of Fas/FasL and survivin in SW579 human thyroid squamous cell carcinoma cell line.
Liu Z, Liu G, Liu X, Li S
Oncology letters 2017 Aug;14(2):2310-2314
Oncology letters 2017 Aug;14(2):2310-2314
Treatment mechanism of matrine in combination with irinotecan for colon cancer.
Duan L, Deng L, Wang D, Ma S, Li C, Zhao D
Oncology letters 2017 Aug;14(2):2300-2304
Oncology letters 2017 Aug;14(2):2300-2304
HRS plays an important role for TLR7 signaling to orchestrate inflammation and innate immunity upon EV71 infection.
Luo Z, Ge M, Chen J, Geng Q, Tian M, Qiao Z, Bai L, Zhang Q, Zhu C, Xiong Y, Wu K, Liu F, Liu Y, Wu J
PLoS pathogens 2017 Aug;13(8):e1006585
PLoS pathogens 2017 Aug;13(8):e1006585
Calpain Inhibition Is Protective in Machado-Joseph Disease Zebrafish Due to Induction of Autophagy.
Watchon M, Yuan KC, Mackovski N, Svahn AJ, Cole NJ, Goldsbury C, Rinkwitz S, Becker TS, Nicholson GA, Laird AS
The Journal of neuroscience : the official journal of the Society for Neuroscience 2017 Aug 9;37(32):7782-7794
The Journal of neuroscience : the official journal of the Society for Neuroscience 2017 Aug 9;37(32):7782-7794
The impact of p53 on the early stage replication of retrovirus.
Kinnetz M, Alghamdi F, Racz M, Hu W, Shi B
Virology journal 2017 Aug 9;14(1):151
Virology journal 2017 Aug 9;14(1):151
Platelet Derived Growth Factor Alpha (PDGFRα) Induces the Activation of Cardiac Fibroblasts by Activating c-Kit.
Wang L, Yue Y, Yang X, Fan T, Mei B, Hou J, Liang M, Chen G, Wu Z
Medical science monitor : international medical journal of experimental and clinical research 2017 Aug 6;23:3808-3816
Medical science monitor : international medical journal of experimental and clinical research 2017 Aug 6;23:3808-3816
TIMELESS confers cisplatin resistance in nasopharyngeal carcinoma by activating the Wnt/β-catenin signaling pathway and promoting the epithelial mesenchymal transition.
Liu SL, Lin HX, Lin CY, Sun XQ, Ye LP, Qiu F, Wen W, Hua X, Wu XQ, Li J, Song LB, Guo L
Cancer letters 2017 Aug 28;402:117-130
Cancer letters 2017 Aug 28;402:117-130
CO-releasing molecules-2 attenuates ox-LDL-induced injury in HUVECs by ameliorating mitochondrial function and inhibiting Wnt/β-catenin pathway.
Sun HJ, Xu DY, Sun YX, Xue T, Zhang CX, Zhang ZX, Lin W, Li KX
Biochemical and biophysical research communications 2017 Aug 26;490(3):629-635
Biochemical and biophysical research communications 2017 Aug 26;490(3):629-635
A Chinese herbal formula, Jian-Pi-Yi-Shen decoction, improves muscle atrophy via regulating mitochondrial quality control process in 5/6 nephrectomised rats.
Wang D, Chen J, Liu X, Zheng P, Song G, Yi T, Li S
Scientific reports 2017 Aug 23;7(1):9253
Scientific reports 2017 Aug 23;7(1):9253
Mediator MED23 Links Pigmentation and DNA Repair through the Transcription Factor MITF.
Xia M, Chen K, Yao X, Xu Y, Yao J, Yan J, Shao Z, Wang G
Cell reports 2017 Aug 22;20(8):1794-1804
Cell reports 2017 Aug 22;20(8):1794-1804
Activation of Nrf2/ARE signaling pathway attenuates lanthanum chloride induced injuries in primary rat astrocytes.
Zhang L, Yang J, Wu S, Jin C, Lu X, Hu X, Sun Y, Gao X, Cai Y
Metallomics : integrated biometal science 2017 Aug 16;9(8):1120-1131
Metallomics : integrated biometal science 2017 Aug 16;9(8):1120-1131
Seneca Valley Virus Suppresses Host Type I Interferon Production by Targeting Adaptor Proteins MAVS, TRIF, and TANK for Cleavage.
Qian S, Fan W, Liu T, Wu M, Zhang H, Cui X, Zhou Y, Hu J, Wei S, Chen H, Li X, Qian P
Journal of virology 2017 Aug 15;91(16)
Journal of virology 2017 Aug 15;91(16)
microRNA-451-modulated hnRNP A1 takes a part in granulocytic differentiation regulation and acute myeloid leukemia.
Song L, Lin HS, Gong JN, Han H, Wang XS, Su R, Chen MT, Shen C, Ma YN, Yu J, Zhang JW
Oncotarget 2017 Aug 15;8(33):55453-55466
Oncotarget 2017 Aug 15;8(33):55453-55466
Neuronal zinc-α2-glycoprotein is decreased in temporal lobe epilepsy in patients and rats.
Liu Y, Wang T, Liu X, Wei X, Xu T, Yin M, Ding X, Mo L, Chen L
Neuroscience 2017 Aug 15;357:56-66
Neuroscience 2017 Aug 15;357:56-66
Flavonoid glycosides isolated from Epimedium brevicornum and their estrogen biosynthesis-promoting effects.
Li F, Du BW, Lu DF, Wu WX, Wongkrajang K, Wang L, Pu WC, Liu CL, Liu HW, Wang MK, Wang F
Scientific reports 2017 Aug 10;7(1):7760
Scientific reports 2017 Aug 10;7(1):7760
AMPK Serves as a Therapeutic Target Against Anemia of Inflammation.
Wang M, Xin H, Tang W, Li Y, Zhang Z, Fan L, Miao L, Tan B, Wang X, Zhu YZ
Antioxidants & redox signaling 2017 Aug 10;27(5):251-268
Antioxidants & redox signaling 2017 Aug 10;27(5):251-268
Role of RAS/Wnt/β-catenin axis activation in the pathogenesis of podocyte injury and tubulo-interstitial nephropathy.
Chen L, Chen DQ, Wang M, Liu D, Chen H, Dou F, Vaziri ND, Zhao YY
Chemico-biological interactions 2017 Aug 1;273:56-72
Chemico-biological interactions 2017 Aug 1;273:56-72
Transcription factor GATA3 expression is induced by GLS2 overexpression in a glioblastoma cell line but is GLS2-independent in patient-derived glioblastoma.
Majewska E, Rola R, Barczewska M, Marquez J, Albrecht J, Szeliga M
Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 2017 Apr;68(2):209-214
Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 2017 Apr;68(2):209-214
The role of metastasis-associated in colon cancer 1 (MACC1) in endometrial carcinoma tumorigenesis and progression.
Chen S, Zong ZH, Wu DD, Sun KX, Liu BL, Zhao Y
Molecular carcinogenesis 2017 Apr;56(4):1361-1371
Molecular carcinogenesis 2017 Apr;56(4):1361-1371
Isoquercetin Ameliorates Cerebral Impairment in Focal Ischemia Through Anti-Oxidative, Anti-Inflammatory, and Anti-Apoptotic Effects in Primary Culture of Rat Hippocampal Neurons and Hippocampal CA1 Region of Rats.
Wang CP, Shi YW, Tang M, Zhang XC, Gu Y, Liang XM, Wang ZW, Ding F
Molecular neurobiology 2017 Apr;54(3):2126-2142
Molecular neurobiology 2017 Apr;54(3):2126-2142
The protective effect of dopamine on ventilator-induced lung injury via the inhibition of NLRP3 inflammasome.
Yang X, Sun X, Chen H, Xi G, Hou Y, Wu J, Liu D, Wang H, Hou Y, Yu J
International immunopharmacology 2017 Apr;45:68-73
International immunopharmacology 2017 Apr;45:68-73
Down-regulation of Pin1 in Temporal Lobe Epilepsy Patients and Mouse Model.
Tang L, Zhang Y, Chen G, Xiong Y, Wang X, Zhu B
Neurochemical research 2017 Apr;42(4):1211-1218
Neurochemical research 2017 Apr;42(4):1211-1218
Protective effect of naringin against the LPS-induced apoptosis of PC12 cells: Implications for the treatment of neurodegenerative disorders.
Wang H, Xu YS, Wang ML, Cheng C, Bian R, Yuan H, Wang Y, Guo T, Zhu LL, Zhou H
International journal of molecular medicine 2017 Apr;39(4):819-830
International journal of molecular medicine 2017 Apr;39(4):819-830
miR-92a promotes tumor growth of osteosarcoma by targeting PTEN/AKT signaling pathway.
Xiao J, Yu W, Hu K, Li M, Chen J, Li Z
Oncology reports 2017 Apr;37(4):2513-2521
Oncology reports 2017 Apr;37(4):2513-2521
miR-30a radiosensitizes non-small cell lung cancer by targeting ATF1 that is involved in the phosphorylation of ATM.
Guo Y, Sun W, Gong T, Chai Y, Wang J, Hui B, Li Y, Song L, Gao Y
Oncology reports 2017 Apr;37(4):1980-1988
Oncology reports 2017 Apr;37(4):1980-1988
Low expression of TMEM67 is a critical predictor of poor prognosis in human urothelial carcinoma of the bladder.
Du E, Zhang C, Qin Z, Yang K, Li C, Wang A, Zhang Z, Xu Y
Urologic oncology 2017 Apr;35(4):152.e7-152.e12
Urologic oncology 2017 Apr;35(4):152.e7-152.e12
The Selective Serotonin Reuptake Inhibitor Fluoxetine Directly Inhibits Osteoblast Differentiation and Mineralization During Fracture Healing in Mice.
Bradaschia-Correa V, Josephson AM, Mehta D, Mizrahi M, Neibart SS, Liu C, Kennedy OD, Castillo AB, Egol KA, Leucht P
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2017 Apr;32(4):821-833
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2017 Apr;32(4):821-833
Interleukin 6 induces cell proliferation of clear cell renal cell carcinoma by suppressing hepaCAM via the STAT3-dependent up-regulation of DNMT1 or DNMT3b.
Quan Z, He Y, Luo C, Xia Y, Zhao Y, Liu N, Wu X
Cellular signalling 2017 Apr;32:48-58
Cellular signalling 2017 Apr;32:48-58
Histone deacetylase inhibitor apicidin increases expression of the α-secretase ADAM10 through transcription factor USF1-mediated mechanisms.
Hu XT, Zhu BL, Zhao LG, Wang JW, Liu L, Lai YJ, He L, Deng XJ, Chen GJ
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2017 Apr;31(4):1482-1493
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2017 Apr;31(4):1482-1493
Blocking the recruitment of naive CD4(+) T cells reverses immunosuppression in breast cancer.
Su S, Liao J, Liu J, Huang D, He C, Chen F, Yang L, Wu W, Chen J, Lin L, Zeng Y, Ouyang N, Cui X, Yao H, Su F, Huang JD, Lieberman J, Liu Q, Song E
Cell research 2017 Apr;27(4):461-482
Cell research 2017 Apr;27(4):461-482
Non-hemolytic enterotoxin of Bacillus cereus induces apoptosis in Vero cells.
Liu X, Ding S, Shi P, Dietrich R, Märtlbauer E, Zhu K
Cellular microbiology 2017 Apr;19(4)
Cellular microbiology 2017 Apr;19(4)
Activation of ATP-sensitive potassium channel by iptakalim normalizes stress-induced HPA axis disorder and depressive behaviour by alleviating inflammation and oxidative stress in mouse hypothalamus.
Zhao XJ, Zhao Z, Yang DD, Cao LL, Zhang L, Ji J, Gu J, Huang JY, Sun XL
Brain research bulletin 2017 Apr;130:146-155
Brain research bulletin 2017 Apr;130:146-155
GP73 represses host innate immune response to promote virus replication by facilitating MAVS and TRAF6 degradation.
Zhang X, Zhu C, Wang T, Jiang H, Ren Y, Zhang Q, Wu K, Liu F, Liu Y, Wu J
PLoS pathogens 2017 Apr;13(4):e1006321
PLoS pathogens 2017 Apr;13(4):e1006321
Quercetin exerts preventive, ameliorative and prophylactic effects on cadmium chloride - induced oxidative stress in the uterus and ovaries of female Wistar rats.
Nna VU, Usman UZ, Ofutet EO, Owu DU
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2017 Apr;102:143-155
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2017 Apr;102:143-155
Induction of pro-inflammatory genes by serum amyloid A1 in human amnion fibroblasts.
Li W, Wang W, Zuo R, Liu C, Shu Q, Ying H, Sun K
Scientific reports 2017 Apr 6;7(1):693
Scientific reports 2017 Apr 6;7(1):693
Bone marrow-derived mesenchymal stem cells (BMSCs) repair acute necrotized pancreatitis by secreting microRNA-9 to target the NF-κB1/p50 gene in rats.
Qian D, Wei G, Xu C, He Z, Hua J, Li J, Hu Q, Lin S, Gong J, Meng H, Zhou B, Teng H, Song Z
Scientific reports 2017 Apr 3;7(1):581
Scientific reports 2017 Apr 3;7(1):581
HMGCS2 promotes autophagic degradation of the amyloid-β precursor protein through ketone body-mediated mechanisms.
Hu LT, Zhu BL, Lai YJ, Long Y, Zha JS, Hu XT, Zhang JH, Chen GJ
Biochemical and biophysical research communications 2017 Apr 29;486(2):492-498
Biochemical and biophysical research communications 2017 Apr 29;486(2):492-498
Atorvastatin prevents Angiotensin II induced myocardial hypertrophy in vitro via CCAAT/enhancer-binding protein β.
Chen Y, Yu S, Zhang N, Li Y, Chen S, Chang Y, Sun G, Sun Y
Biochemical and biophysical research communications 2017 Apr 29;486(2):423-430
Biochemical and biophysical research communications 2017 Apr 29;486(2):423-430
DNA replication licensing factor Cdc6 and Plk4 kinase antagonistically regulate centrosome duplication via Sas-6.
Xu X, Huang S, Zhang B, Huang F, Chi W, Fu J, Wang G, Li S, Jiang Q, Zhang C
Nature communications 2017 Apr 27;8:15164
Nature communications 2017 Apr 27;8:15164
CtBP2 overexpression promotes tumor cell proliferation and invasion in gastric cancer and is associated with poor prognosis.
Dai F, Xuan Y, Jin JJ, Yu S, Long ZW, Cai H, Liu XW, Zhou Y, Wang YN, Chen Z, Huang H
Oncotarget 2017 Apr 25;8(17):28736-28749
Oncotarget 2017 Apr 25;8(17):28736-28749
Amelioration of amyloid-β-induced deficits by DcR3 in an Alzheimer's disease model.
Liu YL, Chen WT, Lin YY, Lu PH, Hsieh SL, Cheng IH
Molecular neurodegeneration 2017 Apr 24;12(1):30
Molecular neurodegeneration 2017 Apr 24;12(1):30
Exenatide improves liver mitochondrial dysfunction and insulin resistance by reducing oxidative stress in high fat diet-induced obese mice.
Wang Z, Hou L, Huang L, Guo J, Zhou X
Biochemical and biophysical research communications 2017 Apr 22;486(1):116-123
Biochemical and biophysical research communications 2017 Apr 22;486(1):116-123
Tumor necrosis factor receptor 2/AKT and ERK signaling pathways contribute to the switch from fibroblasts to CAFs by progranulin in microenvironment of colorectal cancer.
Wang L, Yang D, Tian J, Gao A, Shen Y, Ren X, Li X, Jiang G, Dong T
Oncotarget 2017 Apr 18;8(16):26323-26333
Oncotarget 2017 Apr 18;8(16):26323-26333
Satb2 Ablation Impairs Hippocampus-Based Long-Term Spatial Memory and Short-Term Working Memory and Immediate Early Genes (IEGs)-Mediated Hippocampal Synaptic Plasticity.
Li Y, You QL, Zhang SR, Huang WY, Zou WJ, Jie W, Li SJ, Liu JH, Lv CY, Cong J, Hu YY, Gao TM, Li JM
Molecular neurobiology 2017 Apr 18;
Molecular neurobiology 2017 Apr 18;
Identification, expression pattern and functional characterization of As-kip2 in diapause embryo restarting process of Artemia sinica.
Zhang M, Yao F, Qin T, Hou L, Zou X
Gene 2017 Apr 15;608:28-40
Gene 2017 Apr 15;608:28-40
In vitro biomimetic platforms featuring a perfusion system and 3D spheroid culture promote the construction of tissue-engineered corneal endothelial layers.
Li S, Han Y, Lei H, Zeng Y, Cui Z, Zeng Q, Zhu D, Lian R, Zhang J, Chen Z, Chen J
Scientific reports 2017 Apr 10;7(1):777
Scientific reports 2017 Apr 10;7(1):777
MeCP2 regulated glycogenes contribute to proliferation and apoptosis of gastric cancer cells.
Qin Y, Zhao L, Wang X, Tong D, Hoover C, Wu F, Liu Y, Wang L, Liu L, Ni L, Song T, Huang C
Glycobiology 2017 Apr 1;27(4):306-317
Glycobiology 2017 Apr 1;27(4):306-317
Autophagic Degradation of Collagen 1A1 by Cortisol in Human Amnion Fibroblasts.
Mi Y, Wang W, Zhang C, Liu C, Lu J, Li W, Zuo R, Myatt L, Sun K
Endocrinology 2017 Apr 1;158(4):1005-1014
Endocrinology 2017 Apr 1;158(4):1005-1014
Knockdown of Sall4 inhibits intrahepatic cholangiocarcinoma cell migration and invasion in ICC-9810 cells.
Zhu L, Huang F, Deng G, Nie W, Huang W, Xu H, Zheng S, Yi Z, Wan T
OncoTargets and therapy 2016;9:5297-305
OncoTargets and therapy 2016;9:5297-305
Downregulating hypoxia-inducible factor-1α expression with perfluorooctyl-bromide nanoparticles reduces early brain injury following experimental subarachnoid hemorrhage in rats.
Xu W, Xu R, Li X, Zhang H, Wang X, Zhu J
American journal of translational research 2016;8(5):2114-26
American journal of translational research 2016;8(5):2114-26
Down-regulation of long non-coding RNA FOXD3 antisense RNA 1 (FOXD3-AS1) inhibits cell proliferation, migration, and invasion in malignant glioma cells.
Chen ZH, Hu HK, Zhang CR, Lu CY, Bao Y, Cai Z, Zou YX, Hu GH, Jiang L
American journal of translational research 2016;8(10):4106-4119
American journal of translational research 2016;8(10):4106-4119
Upregulation of long non-coding RNA LINC00152 by SP1 contributes to gallbladder cancer cell growth and tumor metastasis via PI3K/AKT pathway.
Cai Q, Wang ZQ, Wang SH, Li C, Zhu ZG, Quan ZW, Zhang WJ
American journal of translational research 2016;8(10):4068-4081
American journal of translational research 2016;8(10):4068-4081
Autophagy postpones apoptotic cell death in PRRSV infection through Bad-Beclin1 interaction.
Zhou A, Li S, Khan FA, Zhang S
Virulence 2016;7(2):98-109
Virulence 2016;7(2):98-109
Yin-Chen-Hao Tang Attenuates Severe Acute Pancreatitis in Rat: An Experimental Verification of In silico Network Target Prediction.
Xiang H, Wang G, Qu J, Xia S, Tao X, Qi B, Zhang Q, Shang D
Frontiers in pharmacology 2016;7:378
Frontiers in pharmacology 2016;7:378
Exogenous Hydrogen Sulfide Attenuates High Glucose-Induced Cardiotoxicity by Inhibiting NLRP3 Inflammasome Activation by Suppressing TLR4/NF-κB Pathway in H9c2 Cells.
Huang Z, Zhuang X, Xie C, Hu X, Dong X, Guo Y, Li S, Liao X
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2016;40(6):1578-1590
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2016;40(6):1578-1590
Parthenolide Induces Reactive Oxygen Species-Mediated Autophagic Cell Death in Human Osteosarcoma Cells.
Yang C, Yang QO, Kong QJ, Yuan W, Ou Yang YP
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2016;40(1-2):146-154
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2016;40(1-2):146-154
FBXO6-Mediated Ubiquitination and Degradation of Ero1L Inhibits Endoplasmic Reticulum Stress-Induced Apoptosis.
Chen X, Duan LH, Luo PC, Hu G, Yu X, Liu J, Lu H, Liu B
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2016;39(6):2501-2508
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2016;39(6):2501-2508
Effect of Type I Diabetes on the Proteome of Mouse Oocytes.
Jiang G, Zhang G, An T, He Z, Kang L, Yang X, Gu Y, Zhang D, Wang Y, Gao S
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2016;39(6):2320-2330
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2016;39(6):2320-2330
Similar efficacy from specific and non-specific mineralocorticoid receptor antagonist treatment of muscular dystrophy mice.
Lowe J, Floyd KT, Rastogi N, Schultz EJ, Chadwick JA, Swager SA, Zins JG, Kadakia FK, Smart S, Gomez-Sanchez EP, Gomez-Sanchez CE, Raman SV, Janssen PM, Rafael-Fortney JA
Journal of neuromuscular diseases 2016;3(3):395-404
Journal of neuromuscular diseases 2016;3(3):395-404
N-Stearoyl-L-Tyrosine Inhibits the Senescence of Neural Stem/Progenitor Cells Induced by Aβ 1-42 via the CB2 Receptor.
Li WQ, Wang ZJ, Liu S, Hu Y, Yin M, Lu Y
Stem cells international 2016;2016:7419389
Stem cells international 2016;2016:7419389
Neurotrophic Effect of Adipose Tissue-Derived Stem Cells on Erectile Function Recovery by Pigment Epithelium-Derived Factor Secretion in a Rat Model of Cavernous Nerve Injury.
Chen X, Yang Q, Zheng T, Bian J, Sun X, Shi Y, Liang X, Gao G, Liu G, Deng C
Stem cells international 2016;2016:5161248
Stem cells international 2016;2016:5161248
HIV-1 Tat Regulates Occludin and Aβ Transfer Receptor Expression in Brain Endothelial Cells via Rho/ROCK Signaling Pathway.
Chen Y, Huang W, Jiang W, Wu X, Ye B, Zhou X
Oxidative medicine and cellular longevity 2016;2016:4196572
Oxidative medicine and cellular longevity 2016;2016:4196572
MiR-20a-5p represses multi-drug resistance in osteosarcoma by targeting the KIF26B gene.
Pu Y, Yi Q, Zhao F, Wang H, Cai W, Cai S
Cancer cell international 2016;16:64
Cancer cell international 2016;16:64
Forsythoside A Inhibits BVDV Replication via TRAF2-Dependent CD28-4-1BB Signaling in Bovine PBMCs.
Song QJ, Weng XG, Cai DJ, Zhang W, Wang JF
PloS one 2016;11(9):e0162791
PloS one 2016;11(9):e0162791
Finasteride Enhances the Generation of Human Myeloid-Derived Suppressor Cells by Up-Regulating the COX2/PGE2 Pathway.
Zhang S, Wu K, Liu Y, Lin Y, Zhang X, Zhou J, Zhang H, Pan T, Fu Y
PloS one 2016;11(6):e0156549
PloS one 2016;11(6):e0156549
Hepatitis B Virus Stimulated Fibronectin Facilitates Viral Maintenance and Replication through Two Distinct Mechanisms.
Ren S, Wang J, Chen TL, Li HY, Wan YS, Peng NF, Gui XE, Zhu Y
PloS one 2016;11(3):e0152721
PloS one 2016;11(3):e0152721
Electroacupuncture Promotes Remyelination after Cuprizone Treatment by Enhancing Myelin Debris Clearance.
Zhu K, Sun J, Kang Z, Zou Z, Wu G, Wang J
Frontiers in neuroscience 2016;10:613
Frontiers in neuroscience 2016;10:613
Low-Dose Endothelial-Monocyte-Activating Polypeptide-II Induced Autophagy by Down-Regulating miR-20a in U-87 and U-251 Glioma Cells.
Chen J, Liu L, Liu Y, Liu X, Qu C, Meng F, Ma J, Lin Y, Xue Y
Frontiers in cellular neuroscience 2016;10:128
Frontiers in cellular neuroscience 2016;10:128
Fluoride induced endoplasmic reticulum stress and calcium overload in ameloblasts.
Zhang Y, Zhang K, Ma L, Gu H, Li J, Lei S
Archives of oral biology 2016 Sep;69:95-101
Archives of oral biology 2016 Sep;69:95-101
Effects of ZnO nanoparticles on perfluorooctane sulfonate induced thyroid-disrupting on zebrafish larvae.
Du J, Wang S, You H, Liu Z
Journal of environmental sciences (China) 2016 Sep;47:153-164
Journal of environmental sciences (China) 2016 Sep;47:153-164
Curcumin Attenuated Bupivacaine-Induced Neurotoxicity in SH-SY5Y Cells Via Activation of the Akt Signaling Pathway.
Fan YL, Li HC, Zhao W, Peng HH, Huang F, Jiang WH, Xu SY
Neurochemical research 2016 Sep;41(9):2425-32
Neurochemical research 2016 Sep;41(9):2425-32
Evodiamine exerts anti-tumor effects against hepatocellular carcinoma through inhibiting β-catenin-mediated angiogenesis.
Shi L, Yang F, Luo F, Liu Y, Zhang F, Zou M, Liu Q
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2016 Sep;37(9):12791-12803
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2016 Sep;37(9):12791-12803
Angiopoietin-like protein 2 expression is suppressed by angiotensin II via the angiotensin II type 1 receptor in rat cardiomyocytes.
Wang S, Li Y, Miao W, Zhao H, Zhang F, Liu N, Su G, Cai X
Molecular medicine reports 2016 Sep;14(3):2607-13
Molecular medicine reports 2016 Sep;14(3):2607-13
Simultaneous inhibition of the ubiquitin-proteasome system and autophagy enhances apoptosis induced by ER stress aggravators in human pancreatic cancer cells.
Li X, Zhu F, Jiang J, Sun C, Zhong Q, Shen M, Wang X, Tian R, Shi C, Xu M, Peng F, Guo X, Hu J, Ye D, Wang M, Qin R
Autophagy 2016 Sep;12(9):1521-37
Autophagy 2016 Sep;12(9):1521-37
Alternative splicing of spleen tyrosine kinase differentially regulates colorectal cancer progression.
Ni B, Hu J, Chen D, Li L, Chen D, Wang J, Wang L
Oncology letters 2016 Sep;12(3):1737-1744
Oncology letters 2016 Sep;12(3):1737-1744
Structure-based discovery of two antiviral inhibitors targeting the NS3 helicase of Japanese encephalitis virus.
Fang J, Li H, Kong D, Cao S, Peng G, Zhou R, Chen H, Song Y
Scientific reports 2016 Sep 29;6:34550
Scientific reports 2016 Sep 29;6:34550
Regulation of PCGEM1 by p54/nrb in prostate cancer.
Ho TT, Huang J, Zhou N, Zhang Z, Koirala P, Zhou X, Wu F, Ding X, Mo YY
Scientific reports 2016 Sep 29;6:34529
Scientific reports 2016 Sep 29;6:34529
Epigenomic profiling of primary gastric adenocarcinoma reveals super-enhancer heterogeneity.
Ooi WF, Xing M, Xu C, Yao X, Ramlee MK, Lim MC, Cao F, Lim K, Babu D, Poon LF, Lin Suling J, Qamra A, Irwanto A, Qu Zhengzhong J, Nandi T, Lee-Lim AP, Chan YS, Tay ST, Lee MH, Davies JO, Wong WK, Soo KC, Chan WH, Ong HS, Chow P, Wong CY, Rha SY, Liu J, Hillmer AM, Hughes JR, Rozen S, Teh BT, Fullwood MJ, Li S, Tan P
Nature communications 2016 Sep 28;7:12983
Nature communications 2016 Sep 28;7:12983
Control of cortex development by ULK4, a rare risk gene for mental disorders including schizophrenia.
Lang B, Zhang L, Jiang G, Hu L, Lan W, Zhao L, Hunter I, Pruski M, Song NN, Huang Y, Zhang L, St Clair D, McCaig CD, Ding YQ
Scientific reports 2016 Sep 27;6:31126
Scientific reports 2016 Sep 27;6:31126
Selenomethionine Ameliorates Neuropathology in the Olfactory Bulb of a Triple Transgenic Mouse Model of Alzheimer's Disease.
Zhang ZH, Chen C, Wu QY, Zheng R, Chen Y, Liu Q, Ni JZ, Song GL
International journal of molecular sciences 2016 Sep 27;17(10)
International journal of molecular sciences 2016 Sep 27;17(10)
TDP-43 aggregation mirrors TDP-43 knockdown, affecting the expression levels of a common set of proteins.
Prpar Mihevc S, Baralle M, Buratti E, Rogelj B
Scientific reports 2016 Sep 26;6:33996
Scientific reports 2016 Sep 26;6:33996
TRIM52 inhibits Japanese Encephalitis Virus replication by degrading the viral NS2A.
Fan W, Wu M, Qian S, Zhou Y, Chen H, Li X, Qian P
Scientific reports 2016 Sep 26;6:33698
Scientific reports 2016 Sep 26;6:33698
Polyphenols from hawthorn peels and fleshes differently mitigate dyslipidemia, inflammation and oxidative stress in association with modulation of liver injury in high fructose diet-fed mice.
Han X, Li W, Huang D, Yang X
Chemico-biological interactions 2016 Sep 25;257:132-40
Chemico-biological interactions 2016 Sep 25;257:132-40
Reversal of cisplatin resistance in non-small cell lung cancer stem cells by Taxus chinensis var.
Jiang YQ, Xu XP, Guo QM, Xu XC, Liu QY, An SH, Xu JL, Su F, Tai JB
Genetics and molecular research : GMR 2016 Sep 2;15(3)
Genetics and molecular research : GMR 2016 Sep 2;15(3)
Triplex structures induce DNA double strand breaks via replication fork collapse in NER deficient cells.
Kaushik Tiwari M, Adaku N, Peart N, Rogers FA
Nucleic acids research 2016 Sep 19;44(16):7742-54
Nucleic acids research 2016 Sep 19;44(16):7742-54
miR-106a promotes cardiac hypertrophy by targeting mitofusin 2.
Guan X, Wang L, Liu Z, Guo X, Jiang Y, Lu Y, Peng Y, Liu T, Yang B, Shan H, Zhang Y, Xu C
Journal of molecular and cellular cardiology 2016 Oct;99:207-217
Journal of molecular and cellular cardiology 2016 Oct;99:207-217
SIRT1 activator ameliorates the renal tubular injury induced by hyperglycemia in vivo and in vitro via inhibiting apoptosis.
Wang XL, Wu LY, Zhao L, Sun LN, Liu HY, Liu G, Guan GJ
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2016 Oct;83:41-50
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2016 Oct;83:41-50
Prognostic value of mixed lineage kinase domain-like protein expression in the survival of patients with gastric caner.
Ertao Z, Jianhui C, Kang W, Zhijun Y, Hui W, Chuangqi C, Changjiang Q, Sile C, Yulong H, Shirong C
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2016 Oct;37(10):13679-13685
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2016 Oct;37(10):13679-13685
Neuroprotective Effects of Dexmedetomidine Against Hypoxia-Induced Nervous System Injury are Related to Inhibition of NF-κB/COX-2 Pathways.
Pan W, Lin L, Zhang N, Yuan F, Hua X, Wang Y, Mo L
Cellular and molecular neurobiology 2016 Oct;36(7):1179-88
Cellular and molecular neurobiology 2016 Oct;36(7):1179-88
Inhibition of Lysyl Oxidase by Cortisol Regeneration in Human Amnion: Implications for Rupture of Fetal Membranes.
Liu C, Guo C, Wang W, Zhu P, Li W, Mi Y, Myatt L, Sun K
Endocrinology 2016 Oct;157(10):4055-4065
Endocrinology 2016 Oct;157(10):4055-4065
Nanoparticle-facilitated autophagy inhibition promotes the efficacy of chemotherapeutics against breast cancer stem cells.
Sun R, Shen S, Zhang YJ, Xu CF, Cao ZT, Wen LP, Wang J
Biomaterials 2016 Oct;103:44-55
Biomaterials 2016 Oct;103:44-55
Long non-coding RNA H19 regulates FOXM1 expression by competitively binding endogenous miR-342-3p in gallbladder cancer.
Wang SH, Ma F, Tang ZH, Wu XC, Cai Q, Zhang MD, Weng MZ, Zhou D, Wang JD, Quan ZW
Journal of experimental & clinical cancer research : CR 2016 Oct 3;35(1):160
Journal of experimental & clinical cancer research : CR 2016 Oct 3;35(1):160
Golgi protein 73 facilitates the interaction of hepatitis C virus NS5A with apolipoprotein E to promote viral particle secretion.
Zhang X, Wang T, Dai X, Zhang Y, Jiang H, Zhang Q, Liu F, Wu K, Liu Y, Zhou H, Wu J
Biochemical and biophysical research communications 2016 Oct 28;479(4):683-689
Biochemical and biophysical research communications 2016 Oct 28;479(4):683-689
Dioscin attenuates gastric ischemia/reperfusion injury through the down-regulation of PKC/ERK1/2 signaling via PKCα and PKCβ2 inhibition.
Hu Y, Tao X, Han X, Xu L, Yin L, Qi Y, Zhao Y, Xu Y, Wang C, Peng J
Chemico-biological interactions 2016 Oct 25;258:234-44
Chemico-biological interactions 2016 Oct 25;258:234-44
Depletion of thymopoietin inhibits proliferation and induces cell cycle arrest/apoptosis in glioblastoma cells.
Zhang L, Wang G, Chen S, Ding J, Ju S, Cao H, Tian H
World journal of surgical oncology 2016 Oct 19;14(1):267
World journal of surgical oncology 2016 Oct 19;14(1):267
Afamin promotes glucose metabolism in papillary thyroid carcinoma.
Shen CT, Wei WJ, Qiu ZL, Song HJ, Luo QY
Molecular and cellular endocrinology 2016 Oct 15;434:108-15
Molecular and cellular endocrinology 2016 Oct 15;434:108-15
Olig2-Targeted G-Protein-Coupled Receptor Gpr17 Regulates Oligodendrocyte Survival in Response to Lysolecithin-Induced Demyelination.
Ou Z, Sun Y, Lin L, You N, Liu X, Li H, Ma Y, Cao L, Han Y, Liu M, Deng Y, Yao L, Lu QR, Chen Y
The Journal of neuroscience : the official journal of the Society for Neuroscience 2016 Oct 12;36(41):10560-10573
The Journal of neuroscience : the official journal of the Society for Neuroscience 2016 Oct 12;36(41):10560-10573
Cleavage and polyadenylation specific factor 4 targets NF-κB/cyclooxygenase-2 signaling to promote lung cancer growth and progression.
Yi C, Wang Y, Zhang C, Xuan Y, Zhao S, Liu T, Li W, Liao Y, Feng X, Hao J, Gao Y, Yu W, Chen Y, Zhang C, Guo W, Tang B, Deng W
Cancer letters 2016 Oct 10;381(1):1-13
Cancer letters 2016 Oct 10;381(1):1-13
25-Hydroxycholesterol impairs endothelial function and vasodilation by uncoupling and inhibiting endothelial nitric oxide synthase.
Ou ZJ, Chen J, Dai WP, Liu X, Yang YK, Li Y, Lin ZB, Wang TT, Wu YY, Su DH, Cheng TP, Wang ZP, Tao J, Ou JS
American journal of physiology. Endocrinology and metabolism 2016 Oct 1;311(4):E781-E790
American journal of physiology. Endocrinology and metabolism 2016 Oct 1;311(4):E781-E790
Tim-4 protects mice against lipopolysaccharide-induced endotoxic shock by suppressing the NF-κB signaling pathway.
Xu L, Zhao P, Xu Y, Gao L, Wang H, Jia X, Ma H, Liang X, Ma C, Gao L
Laboratory investigation; a journal of technical methods and pathology 2016 Nov;96(11):1189-1197
Laboratory investigation; a journal of technical methods and pathology 2016 Nov;96(11):1189-1197
MicroRNA124 Regulated Neurite Elongation by Targeting OSBP.
Gu X, Li A, Liu S, Lin L, Xu S, Zhang P, Li S, Li X, Tian B, Zhu X, Wang X
Molecular neurobiology 2016 Nov;53(9):6388-6396
Molecular neurobiology 2016 Nov;53(9):6388-6396
Transplantation of Human Urine-Derived Stem Cells Transfected with Pigment Epithelium-Derived Factor to Protect Erectile Function in a Rat Model of Cavernous Nerve Injury.
Yang Q, Chen X, Zheng T, Han D, Zhang H, Shi Y, Bian J, Sun X, Xia K, Liang X, Liu G, Zhang Y, Deng C
Cell transplantation 2016 Nov;25(11):1987-2001
Cell transplantation 2016 Nov;25(11):1987-2001
Cyclooxygenase-2 is associated with malignant phenotypes in human lung cancer.
Li W, Yue W, Wang H, Lai B, Yang X, Zhang C, Wang Y, Gu M
Oncology letters 2016 Nov;12(5):3836-3844
Oncology letters 2016 Nov;12(5):3836-3844
Sargassum fusiforme polysaccharides activate antioxidant defense by promoting Nrf2-dependent cytoprotection and ameliorate stress insult during aging.
Chen P, He D, Zhang Y, Yang S, Chen L, Wang S, Zou H, Liao Z, Zhang X, Wu M
Food & function 2016 Nov 9;7(11):4576-4588
Food & function 2016 Nov 9;7(11):4576-4588
Promotive effects of bone morphogenetic protein 2 on angiogenesis in hepatocarcinoma via multiple signal pathways.
Zuo WH, Zeng P, Chen X, Lu YJ, Li A, Wu JB
Scientific reports 2016 Nov 25;6:37499
Scientific reports 2016 Nov 25;6:37499
NR4A1 Knockdown Suppresses Seizure Activity by Regulating Surface Expression of NR2B.
Zhang Y, Chen G, Gao B, Li Y, Liang S, Wang X, Wang X, Zhu B
Scientific reports 2016 Nov 23;6:37713
Scientific reports 2016 Nov 23;6:37713
Quantitative proteomics reveals molecular mechanism of gamabufotalin and its potential inhibition on Hsp90 in lung cancer.
Zhang L, Yu Z, Wang Y, Wang X, Zhang L, Wang C, Yue Q, Wang X, Deng S, Huo X, Tian X, Huang S, Zhang B, Ma X
Oncotarget 2016 Nov 22;7(47):76551-76564
Oncotarget 2016 Nov 22;7(47):76551-76564
Keap1 hypomorphism protects against ischemic and obstructive kidney disease.
Tan RJ, Chartoumpekis DV, Rush BM, Zhou D, Fu H, Kensler TW, Liu Y
Scientific reports 2016 Nov 2;6:36185
Scientific reports 2016 Nov 2;6:36185
Lithium promotes DNA stability and survival of ischemic retinal neurocytes by upregulating DNA ligase IV.
Yang Y, Wu N, Tian S, Li F, Hu H, Chen P, Cai X, Xu L, Zhang J, Chen Z, Ge J, Yu K, Zhuang J
Cell death & disease 2016 Nov 17;7(11):e2473
Cell death & disease 2016 Nov 17;7(11):e2473
microRNA-23a, -27a and -24 synergistically regulate JAK1/Stat3 cascade and serve as novel therapeutic targets in human acute erythroid leukemia.
Su R, Dong L, Zou D, Zhao H, Ren Y, Li F, Yi P, Li L, Zhu Y, Ma Y, Wang J, Wang F, Yu J
Oncogene 2016 Nov 17;35(46):6001-6014
Oncogene 2016 Nov 17;35(46):6001-6014
Neutrophil extracellular traps are indirectly triggered by lipopolysaccharide and contribute to acute lung injury.
Liu S, Su X, Pan P, Zhang L, Hu Y, Tan H, Wu D, Liu B, Li H, Li H, Li Y, Dai M, Li Y, Hu C, Tsung A
Scientific reports 2016 Nov 16;6:37252
Scientific reports 2016 Nov 16;6:37252
Activation of the RLR/MAVS Signaling Pathway by the L Protein of Mopeia Virus.
Zhang LK, Xin QL, Zhu SL, Wan WW, Wang W, Xiao G
Journal of virology 2016 Nov 15;90(22):10259-10270
Journal of virology 2016 Nov 15;90(22):10259-10270
MicroRNA deep sequencing in two adult stem cell populations identifies miR-501 as a novel regulator of myosin heavy chain during muscle regeneration.
Mizbani A, Luca E, Rushing EJ, Krützfeldt J
Development (Cambridge, England) 2016 Nov 15;143(22):4137-4148
Development (Cambridge, England) 2016 Nov 15;143(22):4137-4148
Phosphorylation of STAT2 on serine-734 negatively regulates the IFN-α-induced antiviral response.
Steen HC, Kotredes KP, Nogusa S, Harris MY, Balachandran S, Gamero AM
Journal of cell science 2016 Nov 15;129(22):4190-4199
Journal of cell science 2016 Nov 15;129(22):4190-4199
17β-Estradiol Inhibites Tumor Necrosis Factor-α Induced Apoptosis of Human Nucleus Pulposus Cells via the PI3K/Akt Pathway.
Wang T, Yang SD, Liu S, Wang H, Liu H, Ding WY
Medical science monitor : international medical journal of experimental and clinical research 2016 Nov 12;22:4312-4322
Medical science monitor : international medical journal of experimental and clinical research 2016 Nov 12;22:4312-4322
Deletion of Pr130 Interrupts Cardiac Development in Zebrafish.
Yang J, Li Z, Gan X, Zhai G, Gao J, Xiong C, Qiu X, Wang X, Yin Z, Zheng F
International journal of molecular sciences 2016 Nov 11;17(11)
International journal of molecular sciences 2016 Nov 11;17(11)
Downregulation of myosin VI reduced cell growth and increased apoptosis in human colorectal cancer.
You W, Tan G, Sheng N, Gong J, Yan J, Chen D, Zhang H, Wang Z
Acta biochimica et biophysica Sinica 2016 May;48(5):430-6
Acta biochimica et biophysica Sinica 2016 May;48(5):430-6
Pristimerin overcomes adriamycin resistance in breast cancer cells through suppressing Akt signaling.
Xie G, Yu X, Liang H, Chen J, Tang X, Wu S, Liao C
Oncology letters 2016 May;11(5):3111-3116
Oncology letters 2016 May;11(5):3111-3116
Downregulation of ATOH8 induced by EBV-encoded LMP1 contributes to the malignant phenotype of nasopharyngeal carcinoma.
Wang Z, Xie J, Yan M, Wang J, Wang X, Zhang J, Zhang Y, Li P, Lei X, Huang Q, Lin S, Guo X, Liu Q
Oncotarget 2016 May 3;7(18):26765-79
Oncotarget 2016 May 3;7(18):26765-79
MicroRNA-24 promotes 3T3-L1 adipocyte differentiation by directly targeting the MAPK7 signaling.
Jin M, Wu Y, Wang J, Chen J, Huang Y, Rao J, Feng C
Biochemical and biophysical research communications 2016 May 20;474(1):76-82
Biochemical and biophysical research communications 2016 May 20;474(1):76-82
RBM4 promotes neuronal differentiation and neurite outgrowth by modulating Numb isoform expression.
Tarn WY, Kuo HC, Yu HI, Liu SW, Tseng CT, Dhananjaya D, Hung KY, Tu CC, Chang SH, Huang GJ, Chiu IM
Molecular biology of the cell 2016 May 15;27(10):1676-83
Molecular biology of the cell 2016 May 15;27(10):1676-83
CGP57380 enhances efficacy of RAD001 in non-small cell lung cancer through abrogating mTOR inhibition-induced phosphorylation of eIF4E and activating mitochondrial apoptotic pathway.
Wen Q, Wang W, Luo J, Chu S, Chen L, Xu L, Zang H, Alnemah MM, Ma J, Fan S
Oncotarget 2016 May 10;7(19):27787-801
Oncotarget 2016 May 10;7(19):27787-801
MiR-146a affects the alteration in myeloid differentiation induced by hydroquinone in human CD34(+) hematopoietic progenitor cells and HL-60 cells.
Yuan W, Sun Q, Jiang Y, Zhang X, Chen L, Xie C, Qin F, Chen Y, Lv H, Chen W, Xiao Y
Toxicology research 2016 May 1;5(3):848-858
Toxicology research 2016 May 1;5(3):848-858
Transcription factor Fli-1 positively regulates lipopolysaccharide-induced interleukin-27 production in macrophages.
Gao P, Yuan M, Ma X, Jiang W, Zhu L, Wen M, Xu J, Liu Q, An H
Molecular immunology 2016 Mar;71:184-191
Molecular immunology 2016 Mar;71:184-191
Glutathione S-transferase SlGSTE1 in Spodoptera litura may be associated with feeding adaptation of host plants.
Zou X, Xu Z, Zou H, Liu J, Chen S, Feng Q, Zheng S
Insect biochemistry and molecular biology 2016 Mar;70:32-43
Insect biochemistry and molecular biology 2016 Mar;70:32-43
The protective effect of melatonin on smoke-induced vascular injury in rats and humans: a randomized controlled trial.
Wang Z, Ni L, Wang J, Lu C, Ren M, Han W, Liu C
Journal of pineal research 2016 Mar;60(2):217-27
Journal of pineal research 2016 Mar;60(2):217-27
Akt inhibitor MK-2206 enhances the effect of cisplatin in gastric cancer cells.
Tao K, Yin Y, Shen Q, Chen Y, Li R, Chang W, Bai J, Liu W, Shi L, Zhang P
Biomedical reports 2016 Mar;4(3):365-368
Biomedical reports 2016 Mar;4(3):365-368
Swine TRIM21 restricts FMDV infection via an intracellular neutralization mechanism.
Fan W, Zhang D, Qian P, Qian S, Wu M, Chen H, Li X
Antiviral research 2016 Mar;127:32-40
Antiviral research 2016 Mar;127:32-40
Significance of the NOR1-FOXA1/HDAC2-Slug regulatory network in epithelial-mesenchymal transition of tumor cells.
Wang W, Yi M, Chen S, Li J, Li G, Yang J, Zheng P, Zhang H, Xiong W, McCarthy JB, Li G, Li X, Xiang B
Oncotarget 2016 Mar 29;7(13):16745-59
Oncotarget 2016 Mar 29;7(13):16745-59
Bromodomain-containing protein 7 (BRD7) as a potential tumor suppressor in hepatocellular carcinoma.
Chen CL, Wang Y, Pan QZ, Tang Y, Wang QJ, Pan K, Huang LX, He J, Zhao JJ, Jiang SS, Zhang XF, Zhang HX, Zhou ZQ, Weng de S, Xia JC
Oncotarget 2016 Mar 29;7(13):16248-61
Oncotarget 2016 Mar 29;7(13):16248-61
TGF-β1 activates the canonical NF-κB signaling to promote cell survival and proliferation in dystrophic muscle fibroblasts in vitro.
Ma ZY, Zhong ZG, Qiu MY, Zhong YH, Zhang WX
Biochemical and biophysical research communications 2016 Mar 18;471(4):576-81
Biochemical and biophysical research communications 2016 Mar 18;471(4):576-81
REST alleviates neurotoxic prion peptide-induced synaptic abnormalities, neurofibrillary degeneration and neuronal death partially via LRP6-mediated Wnt-β-catenin signaling.
Song Z, Zhu T, Zhou X, Barrow P, Yang W, Cui Y, Yang L, Zhao D
Oncotarget 2016 Mar 15;7(11):12035-52
Oncotarget 2016 Mar 15;7(11):12035-52
Suppression of prostate cancer progression by cancer cell stemness inhibitor napabucasin.
Zhang Y, Jin Z, Zhou H, Ou X, Xu Y, Li H, Liu C, Li B
Cancer medicine 2016 Jun;5(6):1251-8
Cancer medicine 2016 Jun;5(6):1251-8
A novel conditional gene silencing method using a tumor-specific and heat-inducible siRNA system.
Feng J, Wang X, Liao Y, Feng J, Tang L
Journal of industrial microbiology & biotechnology 2016 Jun;43(6):761-70
Journal of industrial microbiology & biotechnology 2016 Jun;43(6):761-70
Mitigation of tight junction protein dysfunction in lung microvascular endothelial cells with pitavastatin.
Suzuki R, Nakamura Y, Chiba S, Mizuno T, Abe K, Horii Y, Nagashima H, Tanita T, Yamauchi K
Pulmonary pharmacology & therapeutics 2016 Jun;38:27-35
Pulmonary pharmacology & therapeutics 2016 Jun;38:27-35
Oleanolic acid inhibits cell survival and proliferation of prostate cancer cells in vitro and in vivo through the PI3K/Akt pathway.
Li X, Song Y, Zhang P, Zhu H, Chen L, Xiao Y, Xing Y
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2016 Jun;37(6):7599-613
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2016 Jun;37(6):7599-613
Recombinant adeno-associated virus-delivered anginex inhibits angiogenesis and growth of HUVECs by regulating the Akt, JNK and NF-κB signaling pathways.
Ma K, Wang C, Geng Q, Fan Y, Ning J, Yang H, Dong X, Dong D, Guo Y, Wei X, Li E, Wu Y
Oncology reports 2016 Jun;35(6):3505-13
Oncology reports 2016 Jun;35(6):3505-13
Coordinate regulatory osteogenesis effects of icariin, timosaponin B II and ferulic acid from traditional Chinese medicine formulas on UMR-106 osteoblastic cells and osteoblasts in neonatal rat calvaria cultures.
Li M, Zhang ND, Wang Y, Han T, Jiang YP, Rahman K, Qin LP, Xin HL, Zhang QY
Journal of ethnopharmacology 2016 Jun 5;185:120-31
Journal of ethnopharmacology 2016 Jun 5;185:120-31
Downregulation of stathmin 1 in human gallbladder carcinoma inhibits tumor growth in vitro and in vivo.
Wang J, Yao Y, Ming Y, Shen S, Wu N, Liu J, Liu H, Suo T, Pan H, Zhang D, Ding K, Liu H
Scientific reports 2016 Jun 28;6:28833
Scientific reports 2016 Jun 28;6:28833
HuR-regulated lncRNA NEAT1 stability in tumorigenesis and progression of ovarian cancer.
Chai Y, Liu J, Zhang Z, Liu L
Cancer medicine 2016 Jul;5(7):1588-98
Cancer medicine 2016 Jul;5(7):1588-98
Midgut epithelium in molting silkworm: A fine balance among cell growth, differentiation, and survival.
Franzetti E, Casartelli M, D'Antona P, Montali A, Romanelli D, Cappellozza S, Caccia S, Grimaldi A, de Eguileor M, Tettamanti G
Arthropod structure & development 2016 Jul;45(4):368-79
Arthropod structure & development 2016 Jul;45(4):368-79
High TXNDC5 expression predicts poor prognosis in renal cell carcinoma.
Mo R, Peng J, Xiao J, Ma J, Li W, Wang J, Ruan Y, Ma S, Hong Y, Wang C, Gao K, Fan J
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2016 Jul;37(7):9797-806
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2016 Jul;37(7):9797-806
MicroRNA-124 negatively regulates LPS-induced TNF-α production in mouse macrophages by decreasing protein stability.
Sun Y, Qin Z, Li Q, Wan JJ, Cheng MH, Wang PY, Su DF, Yu JG, Liu X
Acta pharmacologica Sinica 2016 Jul;37(7):889-97
Acta pharmacologica Sinica 2016 Jul;37(7):889-97
Berberine in combination with cisplatin suppresses breast cancer cell growth through induction of DNA breaks and caspase-3-dependent apoptosis.
Zhao Y, Jing Z, Li Y, Mao W
Oncology reports 2016 Jul;36(1):567-72
Oncology reports 2016 Jul;36(1):567-72
Malignant gliomas induce and exploit astrocytic mesenchymal-like transition by activating canonical Wnt/β-catenin signaling.
Lu P, Wang Y, Liu X, Wang H, Zhang X, Wang K, Wang Q, Hu R
Medical oncology (Northwood, London, England) 2016 Jul;33(7):66
Medical oncology (Northwood, London, England) 2016 Jul;33(7):66
Comparative Effects of Bile Diversion and Duodenal-Jejunal Bypass on Glucose and Lipid Metabolism in Male Diabetic Rats.
Zhang X, Liu T, Wang Y, Zhong M, Zhang G, Liu S, Wu T, Rayner CK, Hu S
Obesity surgery 2016 Jul;26(7):1565-75
Obesity surgery 2016 Jul;26(7):1565-75
Influence of orally fed a select mixture of Bacillus probiotics on intestinal T-cell migration in weaned MUC4 resistant pigs following Escherichia coli challenge.
Yang GY, Zhu YH, Zhang W, Zhou D, Zhai CC, Wang JF
Veterinary research 2016 Jul 16;47(1):71
Veterinary research 2016 Jul 16;47(1):71
Persisting and Increasing Neutrophil Infiltration Associates with Gastric Carcinogenesis and E-cadherin Downregulation.
Fu H, Ma Y, Yang M, Zhang C, Huang H, Xia Y, Lu L, Jin W, Cui D
Scientific reports 2016 Jul 14;6:29762
Scientific reports 2016 Jul 14;6:29762
Polyhydroxycurcuminoids but not curcumin upregulate neprilysin and can be applied to the prevention of Alzheimer's disease.
Chen PT, Chen ZT, Hou WC, Yu LC, Chen RP
Scientific reports 2016 Jul 13;6:29760
Scientific reports 2016 Jul 13;6:29760
Homologous recombination-dependent repair of telomeric DSBs in proliferating human cells.
Mao P, Liu J, Zhang Z, Zhang H, Liu H, Gao S, Rong YS, Zhao Y
Nature communications 2016 Jul 11;7:12154
Nature communications 2016 Jul 11;7:12154
Total saponins isolated from Radix et Rhizoma Leonticis suppresses tumor cells growth by regulation of PI3K/Akt/mTOR and p38 MAPK pathways.
Zhan Y, Liu R, Wang W, Li J, Yang XO, Zhang Y
Environmental toxicology and pharmacology 2016 Jan;41:39-44
Environmental toxicology and pharmacology 2016 Jan;41:39-44
Loss of TIM50 suppresses proliferation and induces apoptosis in breast cancer.
Gao SP, Sun HF, Jiang HL, Li LD, Hu X, Xu XE, Jin W
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2016 Jan;37(1):1279-87
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2016 Jan;37(1):1279-87
Knockdown of protein phosphatase 5 inhibits ovarian cancer growth in vitro.
Zheng X, Zhang L, Jin B, Zhang F, Zhang D, Cui L
Oncology letters 2016 Jan;11(1):168-172
Oncology letters 2016 Jan;11(1):168-172
DNA Methylation mediated down-regulating of MicroRNA-33b and its role in gastric cancer.
Yin H, Song P, Su R, Yang G, Dong L, Luo M, Wang B, Gong B, Liu C, Song W, Wang F, Ma Y, Zhang J, Wang W, Yu J
Scientific reports 2016 Jan 5;6:18824
Scientific reports 2016 Jan 5;6:18824
Regulation of SCN3B/scn3b by Interleukin 2 (IL-2): IL-2 modulates SCN3B/scn3b transcript expression and increases sodium current in myocardial cells.
Zhao Y, Sun Q, Zeng Z, Li Q, Zhou S, Zhou M, Xue Y, Cheng X, Xia Y, Wang Q, Tu X
BMC cardiovascular disorders 2016 Jan 4;16:1
BMC cardiovascular disorders 2016 Jan 4;16:1
miR-183 regulates autophagy and apoptosis in colorectal cancer through targeting of UVRAG.
Huangfu L, Liang H, Wang G, Su X, Li L, Du Z, Hu M, Dong Y, Bai X, Liu T, Yang B, Shan H
Oncotarget 2016 Jan 26;7(4):4735-45
Oncotarget 2016 Jan 26;7(4):4735-45
A simple multi-well stretching device to induce inflammatory responses of vascular endothelial cells.
Wang J, Fan B, Wei Y, Suo X, Ding Y
Lab on a chip 2016 Jan 21;16(2):360-7
Lab on a chip 2016 Jan 21;16(2):360-7
Differential requirement of bone morphogenetic protein receptors Ia (ALK3) and Ib (ALK6) in early embryonic patterning and neural crest development.
Schille C, Heller J, Schambony A
BMC developmental biology 2016 Jan 19;16:1
BMC developmental biology 2016 Jan 19;16:1
Increased expression of copine VI in patients with refractory epilepsy and a rat model.
Zhu B, Zha J, Long Y, Hu X, Chen G, Wang X
Journal of the neurological sciences 2016 Jan 15;360:30-6
Journal of the neurological sciences 2016 Jan 15;360:30-6
Ginsenoside Rg3 inhibits epithelial-mesenchymal transition (EMT) and invasion of lung cancer by down-regulating FUT4.
Tian L, Shen D, Li X, Shan X, Wang X, Yan Q, Liu J
Oncotarget 2016 Jan 12;7(2):1619-32
Oncotarget 2016 Jan 12;7(2):1619-32
A novel combination of oridonin and valproic acid in enhancement of apoptosis induction of HL-60 leukemia cells.
Shi M, Ren X, Wang X, Wang H, Liu G, Yuan X, Zheng S, Yu L, Pan S, Song G, Guo Q, Li L, Zhang X, Zhang Z, Ding H, Jiang G
International journal of oncology 2016 Feb;48(2):734-46
International journal of oncology 2016 Feb;48(2):734-46
Effect of LYRM1 knockdown on proliferation, apoptosis, differentiation and mitochondrial function in the P19 cell model of cardiac differentiation in vitro.
Chen YM, Li X, Song GX, Liu M, Fan Y, Wu LJ, Li H, Zhang QJ, Liu YQ, Qian LM
Journal of bioenergetics and biomembranes 2016 Feb;48(1):33-41
Journal of bioenergetics and biomembranes 2016 Feb;48(1):33-41
NudC regulates actin dynamics and ciliogenesis by stabilizing cofilin 1.
Zhang C, Zhang W, Lu Y, Yan X, Yan X, Zhu X, Liu W, Yang Y, Zhou T
Cell research 2016 Feb;26(2):239-53
Cell research 2016 Feb;26(2):239-53
Role of KIF2A in the progression and metastasis of human glioma.
Zhang X, Ma C, Wang Q, Liu J, Tian M, Yuan Y, Li X, Qu X
Molecular medicine reports 2016 Feb;13(2):1781-7
Molecular medicine reports 2016 Feb;13(2):1781-7
Nanocomplexes from RGD-modified generation 1.0 polyamidoamine based copolymers used for intravascular gene release to prevent restenosis.
Cao D, Tian S, Yi W, Dai G, Chen J, Feng M, Pan S
Nanomedicine (London, England) 2016 Feb;11(4):359-75
Nanomedicine (London, England) 2016 Feb;11(4):359-75
PGRN promotes migration and invasion of epithelial ovarian cancer cells through an epithelial mesenchymal transition program and the activation of cancer associated fibroblasts.
Dong T, Yang D, Li R, Zhang L, Zhao H, Shen Y, Zhang X, Kong B, Wang L
Experimental and molecular pathology 2016 Feb;100(1):17-25
Experimental and molecular pathology 2016 Feb;100(1):17-25
CREB-binding protein regulates lung cancer growth by targeting MAPK and CPSF4 signaling pathway.
Tang Z, Yu W, Zhang C, Zhao S, Yu Z, Xiao X, Tang R, Xuan Y, Yang W, Hao J, Xu T, Zhang Q, Huang W, Deng W, Guo W
Molecular oncology 2016 Feb;10(2):317-29
Molecular oncology 2016 Feb;10(2):317-29
MicroRNA-372 inhibits endometrial carcinoma development by targeting the expression of the Ras homolog gene family member C (RhoC).
Liu BL, Sun KX, Zong ZH, Chen S, Zhao Y
Oncotarget 2016 Feb 9;7(6):6649-64
Oncotarget 2016 Feb 9;7(6):6649-64
RNF135, RING finger protein, promotes the proliferation of human glioblastoma cells in vivo and in vitro via the ERK pathway.
Liu Y, Wang F, Liu Y, Yao Y, Lv X, Dong B, Li J, Ren S, Yao Y, Xu Y
Scientific reports 2016 Feb 9;6:20642
Scientific reports 2016 Feb 9;6:20642
Decreased TPD52 expression is associated with poor prognosis in primary hepatocellular carcinoma.
Wang Y, Chen CL, Pan QZ, Wu YY, Zhao JJ, Jiang SS, Chao J, Zhang XF, Zhang HX, Zhou ZQ, Tang Y, Huang XQ, Zhang JH, Xia JC
Oncotarget 2016 Feb 2;7(5):6323-34
Oncotarget 2016 Feb 2;7(5):6323-34
Thrombospondin-1 might be a therapeutic target to suppress RB cells by regulating the DNA double-strand breaks repair.
Chen P, Yu N, Zhang Z, Zhang P, Yang Y, Wu N, Xu L, Zhang J, Ge J, Yu K, Zhuang J
Oncotarget 2016 Feb 2;7(5):6105-20
Oncotarget 2016 Feb 2;7(5):6105-20
Lactobacillus rhamnosus GR-1 Ameliorates Escherichia coli-Induced Inflammation and Cell Damage via Attenuation of ASC-Independent NLRP3 Inflammasome Activation.
Wu Q, Liu MC, Yang J, Wang JF, Zhu YH
Applied and environmental microbiology 2016 Feb 15;82(4):1173-1182
Applied and environmental microbiology 2016 Feb 15;82(4):1173-1182
DLX3 negatively regulates osteoclastic differentiation through microRNA-124.
Zhao N, Han D, Liu Y, Li Y, Zeng L, Wang Y, Feng H
Experimental cell research 2016 Feb 15;341(2):166-76
Experimental cell research 2016 Feb 15;341(2):166-76
Mammalian cells lacking either the cotranslational or posttranslocational oligosaccharyltransferase complex display substrate-dependent defects in asparagine linked glycosylation.
Cherepanova NA, Gilmore R
Scientific reports 2016 Feb 11;6:20946
Scientific reports 2016 Feb 11;6:20946
Effects of total flavonoids from Drynariae Rhizoma prevent bone loss in vivo and in vitro.
Song SH, Zhai YK, Li CQ, Yu Q, Lu Y, Zhang Y, Hua WP, Wang ZZ, Shang P
Bone reports 2016 Dec;5:262-273
Bone reports 2016 Dec;5:262-273
Life-cycle exposure to BDE-47 results in thyroid endocrine disruption to adults and offsprings of zebrafish (Danio rerio).
Zhao X, Ren X, Ren B, Luo Z, Zhu R
Environmental toxicology and pharmacology 2016 Dec;48:157-167
Environmental toxicology and pharmacology 2016 Dec;48:157-167
Angelicin inhibits human lung carcinoma A549 cell growth and migration through regulating JNK and ERK pathways.
Li G, He Y, Yao J, Huang C, Song X, Deng Y, Xie S, Ren J, Jin M, Liu H
Oncology reports 2016 Dec;36(6):3504-3512
Oncology reports 2016 Dec;36(6):3504-3512
Developmental regulation of CYP3A4 and CYP3A7 in Chinese Han population.
He H, Nie YL, Li JF, Meng XG, Yang WH, Chen YL, Wang SJ, Ma X, Kan QC, Zhang LR
Drug metabolism and pharmacokinetics 2016 Dec;31(6):433-444
Drug metabolism and pharmacokinetics 2016 Dec;31(6):433-444
The lncRNA MALAT1 functions as a competing endogenous RNA to regulate MCL-1 expression by sponging miR-363-3p in gallbladder cancer.
Wang SH, Zhang WJ, Wu XC, Weng MZ, Zhang MD, Cai Q, Zhou D, Wang JD, Quan ZW
Journal of cellular and molecular medicine 2016 Dec;20(12):2299-2308
Journal of cellular and molecular medicine 2016 Dec;20(12):2299-2308
Oligosaccharyltransferase inhibition induces senescence in RTK-driven tumor cells.
Lopez-Sambrooks C, Shrimal S, Khodier C, Flaherty DP, Rinis N, Charest JC, Gao N, Zhao P, Wells L, Lewis TA, Lehrman MA, Gilmore R, Golden JE, Contessa JN
Nature chemical biology 2016 Dec;12(12):1023-1030
Nature chemical biology 2016 Dec;12(12):1023-1030
Interaction between endogenous carbon monoxide and hydrogen sulfide in the mechanism of gastroprotection against acute aspirin-induced gastric damage.
Magierowski M, Magierowska K, Hubalewska-Mazgaj M, Adamski J, Bakalarz D, Sliwowski Z, Pajdo R, Kwiecien S, Brzozowski T
Pharmacological research 2016 Dec;114:235-250
Pharmacological research 2016 Dec;114:235-250
Vam3 ameliorates total body irradiation-induced hematopoietic system injury partly by regulating the expression of Nrf2-targeted genes.
Zhang J, Xue X, Han X, Yao C, Lu L, Li D, Hou Q, Miao W, Meng A, Fan S
Free radical biology & medicine 2016 Dec;101:455-464
Free radical biology & medicine 2016 Dec;101:455-464
Repression of CDKN2C caused by PML/RARα binding promotes the proliferation and differentiation block in acute promyelocytic leukemia.
Wang X, Tan Y, Li Y, Li J, Jin W, Wang K
Frontiers of medicine 2016 Dec;10(4):420-429
Frontiers of medicine 2016 Dec;10(4):420-429
Senescence: novel insight into DLX3 mutations leading to enhanced bone formation in Tricho-Dento-Osseous syndrome.
Zhao N, Han D, Liu H, Li Y, Wong SW, Cao Z, Xu J, Zhang X, Cai T, Wang Y, Feng H
Scientific reports 2016 Dec 7;6:38680
Scientific reports 2016 Dec 7;6:38680
Rab8a/Rab11a regulate intercellular communications between neural cells via tunneling nanotubes.
Zhu H, Xue C, Xu X, Guo Y, Li X, Lu J, Ju S, Wang Y, Cao Z, Gu X
Cell death & disease 2016 Dec 22;7(12):e2523
Cell death & disease 2016 Dec 22;7(12):e2523
Elevated expression of ZNF217 promotes prostate cancer growth by restraining ferroportin-conducted iron egress.
Jiang X, Zhang C, Qi S, Guo S, Chen Y, Du E, Zhang H, Wang X, Liu R, Qiao B, Yang K, Zhang Z, Xu Y
Oncotarget 2016 Dec 20;7(51):84893-84906
Oncotarget 2016 Dec 20;7(51):84893-84906
Unc-5 homolog B (UNC5B) is one of the key downstream targets of N-α-Acetyltransferase 10 (Naa10).
Xu H, Han Y, Liu B, Li R
Scientific reports 2016 Dec 2;6:38508
Scientific reports 2016 Dec 2;6:38508
Up-regulation of granzyme B and perforin by staphylococcal enterotoxin C2 mutant induces enhanced cytotoxicity in Hepa1-6 cells.
Zhang G, Xu M, Zhang H, Song Y, Wang J, Zhang C
Toxicology and applied pharmacology 2016 Dec 15;313:1-9
Toxicology and applied pharmacology 2016 Dec 15;313:1-9
Attribution of NKG2DL to the inhibition of early stage allogeneic tumors in mice.
Hua L, Fang M, Dong B, Guo S, Cui C, Liu J, Yao Y, Xiao Y, Li X, Ren Y, Meng X, Hao X, Zhao P, Song Y, Wang L, Yu Y
Oncotarget 2016 Dec 13;7(50):82369-82383
Oncotarget 2016 Dec 13;7(50):82369-82383
ERK-mediated NF-κB activation through ASIC1 in response to acidosis.
Chen B, Liu J, Ho TT, Ding X, Mo YY
Oncogenesis 2016 Dec 12;5(12):e279
Oncogenesis 2016 Dec 12;5(12):e279
Growth Differentiation Factor-15-Induced Contractile Activity and Extracellular Matrix Production in Human Trabecular Meshwork Cells.
Muralidharan AR, Maddala R, Skiba NP, Rao PV
Investigative ophthalmology & visual science 2016 Dec 1;57(15):6482-6495
Investigative ophthalmology & visual science 2016 Dec 1;57(15):6482-6495
Myeloid cells are capable of synthesizing aldosterone to exacerbate damage in muscular dystrophy.
Chadwick JA, Swager SA, Lowe J, Welc SS, Tidball JG, Gomez-Sanchez CE, Gomez-Sanchez EP, Rafael-Fortney JA
Human molecular genetics 2016 Dec 1;25(23):5167-5177
Human molecular genetics 2016 Dec 1;25(23):5167-5177
Exercise preconditioning reduces neonatal incision surgery-induced enhanced hyperalgesia via inhibition of P38 mitogen-activated protein kinase and IL-1β, TNF-α release.
Gong X, Jiang J, Zhang M
International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience 2016 Aug;52:46-54
International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience 2016 Aug;52:46-54
Low level of FOXL1 indicates a worse prognosis for gastric cancer patients.
Ertao Z, Jianhui C, Chuangqi C, Changjiang Q, Sile C, Yulong H, Shirong C, Hui W
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2016 Aug;37(8):11331-7
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2016 Aug;37(8):11331-7
Dynamic distributions of tumor necrosis factor-alpha and its receptors in the red nucleus of rats with spared nerve injury.
Wang J, Ding CP, Yu J, Zeng XY, Han SP, Wang JY
Neuropathology : official journal of the Japanese Society of Neuropathology 2016 Aug;36(4):346-53
Neuropathology : official journal of the Japanese Society of Neuropathology 2016 Aug;36(4):346-53
LINE-1 gene hypomethylation and p16 gene hypermethylation in HepG2 cells induced by low-dose and long-term triclosan exposure: The role of hydroxyl group.
Zeng L, Ma H, Pan S, You J, Zhang G, Yu Z, Sheng G, Fu J
Toxicology in vitro : an international journal published in association with BIBRA 2016 Aug;34:35-44
Toxicology in vitro : an international journal published in association with BIBRA 2016 Aug;34:35-44
Improvements of Glucose and Lipid Metabolism After Jejuno-ileal Circuit Procedure in a Non-obese Diabetic Rat Model.
Wang Y, Zhang X, Zhong M, Liu T, Zhang G, Liu S, Guo W, Wei M, He Q, Sun D, Hu S
Obesity surgery 2016 Aug;26(8):1768-76
Obesity surgery 2016 Aug;26(8):1768-76
NRAGE is involved in homologous recombination repair to resist the DNA-damaging chemotherapy and composes a ternary complex with RNF8-BARD1 to promote cell survival in squamous esophageal tumorigenesis.
Yang Q, Pan Q, Li C, Xu Y, Wen C, Sun F
Cell death and differentiation 2016 Aug;23(8):1406-16
Cell death and differentiation 2016 Aug;23(8):1406-16
Inhibition of the glucocorticoid receptor results in an enhanced miR-99a/100-mediated radiation response in stem-like cells from human prostate cancers.
Rane JK, Erb HH, Nappo G, Mann VM, Simms MS, Collins AT, Visakorpi T, Maitland NJ
Oncotarget 2016 Aug 9;7(32):51965-51980
Oncotarget 2016 Aug 9;7(32):51965-51980
Paper-based microreactor array for rapid screening of cell signaling cascades.
Huang CH, Lei KF, Tsang NM
Lab on a chip 2016 Aug 7;16(15):2911-20
Lab on a chip 2016 Aug 7;16(15):2911-20
The long noncoding RNA ASNR regulates degradation of Bcl-2 mRNA through its interaction with AUF1.
Chen J, Liu L, Wei G, Wu W, Luo H, Yuan J, Luo J, Chen R
Scientific reports 2016 Aug 31;6:32189
Scientific reports 2016 Aug 31;6:32189
Porcine reproductive and respiratory syndrome virus triggers mitochondrial fission and mitophagy to attenuate apoptosis.
Li S, Wang J, Zhou A, Khan FA, Hu L, Zhang S
Oncotarget 2016 Aug 30;7(35):56002-56012
Oncotarget 2016 Aug 30;7(35):56002-56012
Long non-coding RNA AFAP1-AS1 facilitates tumor growth and promotes metastasis in colorectal cancer.
Han X, Wang L, Ning Y, Li S, Wang Z
Biological research 2016 Aug 30;49(1):36
Biological research 2016 Aug 30;49(1):36
EWSR1 regulates mitosis by dynamically influencing microtubule acetylation.
Wang YL, Chen H, Zhan YQ, Yin RH, Li CY, Ge CH, Yu M, Yang XM
Cell cycle (Georgetown, Tex.) 2016 Aug 17;15(16):2202-2215
Cell cycle (Georgetown, Tex.) 2016 Aug 17;15(16):2202-2215
USP14 regulates autophagy by suppressing K63 ubiquitination of Beclin 1.
Xu D, Shan B, Sun H, Xiao J, Zhu K, Xie X, Li X, Liang W, Lu X, Qian L, Yuan J
Genes & development 2016 Aug 1;30(15):1718-30
Genes & development 2016 Aug 1;30(15):1718-30
Constitutive translation of human α-synuclein is mediated by the 5'-untranslated region.
Koukouraki P, Doxakis E
Open biology 2016 Apr;6(4):160022
Open biology 2016 Apr;6(4):160022
Upregulation of GSK3β Contributes to Brain Disorders in Elderly REGγ-knockout Mice.
Lv Y, Meng B, Dong H, Jing T, Wu N, Yang Y, Huang L, Moses RE, O'Malley BW, Mei B, Li X
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2016 Apr;41(5):1340-9
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2016 Apr;41(5):1340-9
Interplay of autophagy and apoptosis during PRRSV infection of Marc145 cell.
Li S, Zhou A, Wang J, Zhang S
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases 2016 Apr;39:51-54
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases 2016 Apr;39:51-54
Down-regulation of ribosomal protein S15A inhibits proliferation of human glioblastoma cells in vivo and in vitro via AKT pathway.
Yao Y, Liu Y, Lv X, Dong B, Wang F, Li J, Zhang Q, Xu R, Xu Y
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2016 Apr;37(4):4979-90
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2016 Apr;37(4):4979-90
Lead Inhibits Human Sperm Functions by Reducing the Levels of Intracellular Calcium, cAMP, and Tyrosine Phosphorylation.
He Y, Zou Q, Chen H, Weng S, Luo T, Zeng X
The Tohoku journal of experimental medicine 2016 Apr;238(4):295-303
The Tohoku journal of experimental medicine 2016 Apr;238(4):295-303
Altered expression of miR-125a-5p in thymoma-associated myasthenia gravis and its down-regulation of foxp3 expression in Jurkat cells.
Li J, Qiu D, Chen Z, Du W, Liu J, Mo X
Immunology letters 2016 Apr;172:47-55
Immunology letters 2016 Apr;172:47-55
Lentivirus-mediated knockdown of CTDP1 inhibits lung cancer cell growth in vitro.
Zhong R, Ge X, Chu T, Teng J, Yan B, Pei J, Jiang L, Zhong H, Han B
Journal of cancer research and clinical oncology 2016 Apr;142(4):723-32
Journal of cancer research and clinical oncology 2016 Apr;142(4):723-32
Downregulation of VEGF and upregulation of TL1A expression induce HUVEC apoptosis in response to high glucose stimuli.
Yu M, Lu G, Zhu X, Huang Z, Feng C, Fang R, Wang Y, Gao X
Molecular medicine reports 2016 Apr;13(4):3265-72
Molecular medicine reports 2016 Apr;13(4):3265-72
β-Arrestins promote podocyte injury by inhibition of autophagy in diabetic nephropathy.
Liu J, Li QX, Wang XJ, Zhang C, Duan YQ, Wang ZY, Zhang Y, Yu X, Li NJ, Sun JP, Yi F
Cell death & disease 2016 Apr 7;7(4):e2183
Cell death & disease 2016 Apr 7;7(4):e2183
Linc-RoR promotes c-Myc expression through hnRNP I and AUF1.
Huang J, Zhang A, Ho TT, Zhang Z, Zhou N, Ding X, Zhang X, Xu M, Mo YY
Nucleic acids research 2016 Apr 20;44(7):3059-69
Nucleic acids research 2016 Apr 20;44(7):3059-69
Inhibition on Apoptosis Induced by Elevated Hydrostatic Pressure in Retinal Ganglion Cell-5 via Laminin Upregulating β1-integrin/Focal Adhesion Kinase/Protein Kinase B Signaling Pathway.
Li Y, Chen YM, Sun MM, Guo XD, Wang YC, Zhang ZZ
Chinese medical journal 2016 Apr 20;129(8):976-83
Chinese medical journal 2016 Apr 20;129(8):976-83
Autocrine Sonic hedgehog signaling promotes gastric cancer proliferation through induction of phospholipase Cγ1 and the ERK1/2 pathway.
Ertao Z, Jianhui C, Chuangqi C, Changjiang Q, Sile C, Yulong H, Hui W, Shirong C
Journal of experimental & clinical cancer research : CR 2016 Apr 2;35:63
Journal of experimental & clinical cancer research : CR 2016 Apr 2;35:63
A Point Mutation in the Exon Junction Complex Factor Y14 Disrupts Its Function in mRNA Cap Binding and Translation Enhancement.
Chuang TW, Lee KM, Lou YC, Lu CC, Tarn WY
The Journal of biological chemistry 2016 Apr 15;291(16):8565-74
The Journal of biological chemistry 2016 Apr 15;291(16):8565-74
Comparative proteomic study of the response to hypoxia in the muscle of oriental river prawn (Macrobrachium nipponense).
Sun S, Xuan F, Fu H, Ge X, Zhu J, Qiao H, Jin S, Zhang Y
Journal of proteomics 2016 Apr 14;138:115-23
Journal of proteomics 2016 Apr 14;138:115-23
Forced cell cycle exit and modulation of GABAA, CREB, and GSK3β signaling promote functional maturation of induced pluripotent stem cell-derived neurons.
Telezhkin V, Schnell C, Yarova P, Yung S, Cope E, Hughes A, Thompson BA, Sanders P, Geater C, Hancock JM, Joy S, Badder L, Connor-Robson N, Comella A, Straccia M, Bombau G, Brown JT, Canals JM, Randall AD, Allen ND, Kemp PJ
American journal of physiology. Cell physiology 2016 Apr 1;310(7):C520-41
American journal of physiology. Cell physiology 2016 Apr 1;310(7):C520-41
PACE4 regulates apoptosis in human prostate cancer cells via endoplasmic reticulum stress and mitochondrial signaling pathways.
Yao Z, Sun B, Hong Q, Yan J, Mu D, Li J, Sheng H, Guo H
Drug design, development and therapy 2015;9:5911-23
Drug design, development and therapy 2015;9:5911-23
Trefoil factor 1 elevates the malignant phenotype of mucinous ovarian cancer cell through Wnt/β-catenin signaling.
Zhao S, Ma Y, Huang X
International journal of clinical and experimental pathology 2015;8(9):10412-9
International journal of clinical and experimental pathology 2015;8(9):10412-9
Complement factors C1q, C3 and C5b-9 in the posterior sclera of guinea pigs with negative lens-defocused myopia.
Gao TT, Long Q, Yang X
International journal of ophthalmology 2015;8(4):675-80
International journal of ophthalmology 2015;8(4):675-80
Regulative Effect of Nampt on Tumor Progression and Cell Viability in Human Colorectal Cancer.
Lv X, Zhang L, Zhu Y, Said HM, Shi J, Xu G
Journal of Cancer 2015;6(9):849-58
Journal of Cancer 2015;6(9):849-58
Highly expressed UNC119 promotes hepatocellular carcinoma cell proliferation through Wnt/β-catenin signaling and predicts a poor prognosis.
Lei B, Chai W, Wang Z, Liu R
American journal of cancer research 2015;5(10):3123-34
American journal of cancer research 2015;5(10):3123-34
Huaier Aqueous Extract Induces Hepatocellular Carcinoma Cells Arrest in S Phase via JNK Signaling Pathway.
Zhang C, Zhang J, Li X, Sun N, Yu R, Zhao B, Yu D, Cheng Y, Liu Y
Evidence-based complementary and alternative medicine : eCAM 2015;2015:171356
Evidence-based complementary and alternative medicine : eCAM 2015;2015:171356
A Selected Lactobacillus rhamnosus Strain Promotes EGFR-Independent Akt Activation in an Enterotoxigenic Escherichia coli K88-Infected IPEC-J2 Cell Model.
Zhang W, Zhu YH, Yang JC, Yang GY, Zhou D, Wang JF
PloS one 2015;10(4):e0125717
PloS one 2015;10(4):e0125717
Down-Regulation of NDUFB9 Promotes Breast Cancer Cell Proliferation, Metastasis by Mediating Mitochondrial Metabolism.
Li LD, Sun HF, Liu XX, Gao SP, Jiang HL, Hu X, Jin W
PloS one 2015;10(12):e0144441
PloS one 2015;10(12):e0144441
Effects of Carbon Nanotube Environmental Dispersion on an Aquatic Invertebrate, Hirudo medicinalis.
Girardello R, Tasselli S, Baranzini N, Valvassori R, de Eguileor M, Grimaldi A
PloS one 2015;10(12):e0144361
PloS one 2015;10(12):e0144361
CRISPR/Cas9 Promotes Functional Study of Testis Specific X-Linked Gene In Vivo.
Li M, Huang R, Jiang X, Chen Y, Zhang Z, Zhang X, Liang P, Zhan S, Cao S, Songyang Z, Huang J
PloS one 2015;10(11):e0143148
PloS one 2015;10(11):e0143148
Endothelial cell-targeted pVEGF165 polyplex plays a pivotal role in inhibiting intimal thickening after vascular injury.
Tian S, Cao D, Zou H, Bai F, Wang Z, Pan S, Feng M
International journal of nanomedicine 2015;10:5751-68
International journal of nanomedicine 2015;10:5751-68
Circulating microparticles from patients with valvular heart disease and cardiac surgery inhibit endothelium-dependent vasodilation.
Fu L, Hu XX, Lin ZB, Chang FJ, Ou ZJ, Wang ZP, Ou JS
The Journal of thoracic and cardiovascular surgery 2015 Sep;150(3):666-72
The Journal of thoracic and cardiovascular surgery 2015 Sep;150(3):666-72
Effect of Huaier on the proliferation and apoptosis of human gastric cancer cells through modulation of the PI3K/AKT signaling pathway.
Xie HX, Xu ZY, Tang JN, DU YA, Huang L, Yu PF, Cheng XD
Experimental and therapeutic medicine 2015 Sep;10(3):1212-1218
Experimental and therapeutic medicine 2015 Sep;10(3):1212-1218
Phase transition of spindle-associated protein regulate spindle apparatus assembly.
Jiang H, Wang S, Huang Y, He X, Cui H, Zhu X, Zheng Y
Cell 2015 Sep 24;163(1):108-22
Cell 2015 Sep 24;163(1):108-22
SUMOylation at K707 of DGCR8 controls direct function of primary microRNA.
Zhu C, Chen C, Huang J, Zhang H, Zhao X, Deng R, Dou J, Jin H, Chen R, Xu M, Chen Q, Wang Y, Yu J
Nucleic acids research 2015 Sep 18;43(16):7945-60
Nucleic acids research 2015 Sep 18;43(16):7945-60
Prosaposin facilitates sortilin-independent lysosomal trafficking of progranulin.
Zhou X, Sun L, Bastos de Oliveira F, Qi X, Brown WJ, Smolka MB, Sun Y, Hu F
The Journal of cell biology 2015 Sep 14;210(6):991-1002
The Journal of cell biology 2015 Sep 14;210(6):991-1002
Identification of cellular microRNA-136 as a dual regulator of RIG-I-mediated innate immunity that antagonizes H5N1 IAV replication in A549 cells.
Zhao L, Zhu J, Zhou H, Zhao Z, Zou Z, Liu X, Lin X, Zhang X, Deng X, Wang R, Chen H, Jin M
Scientific reports 2015 Oct 9;5:14991
Scientific reports 2015 Oct 9;5:14991
Protein kinase CK2α catalytic subunit is overexpressed and serves as an unfavorable prognostic marker in primary hepatocellular carcinoma.
Zhang HX, Jiang SS, Zhang XF, Zhou ZQ, Pan QZ, Chen CL, Zhao JJ, Tang Y, Xia JC, Weng DS
Oncotarget 2015 Oct 27;6(33):34800-17
Oncotarget 2015 Oct 27;6(33):34800-17
FGF1-FGFR1 axis promotes tongue squamous cell carcinoma (TSCC) metastasis through epithelial-mesenchymal transition (EMT).
Jiao J, Zhao X, Liang Y, Tang D, Pan C
Biochemical and biophysical research communications 2015 Oct 23;466(3):327-32
Biochemical and biophysical research communications 2015 Oct 23;466(3):327-32
BPTF promotes tumor growth and predicts poor prognosis in lung adenocarcinomas.
Dai M, Lu JJ, Guo W, Yu W, Wang Q, Tang R, Tang Z, Xiao Y, Li Z, Sun W, Sun X, Qin Y, Huang W, Deng WG, Wu T
Oncotarget 2015 Oct 20;6(32):33878-92
Oncotarget 2015 Oct 20;6(32):33878-92
Neuroleukin/Autocrine Motility Factor Receptor Pathway Promotes Proliferation of Articular Chondrocytes through Activation of AKT and Smad2/3.
Tian K, Zhong W, Zheng X, Zhang J, Liu P, Zhang W, Liu H
Scientific reports 2015 Oct 13;5:15101
Scientific reports 2015 Oct 13;5:15101
RanGTP aids anaphase entry through Ubr5-mediated protein turnover.
Jiang H, He X, Feng D, Zhu X, Zheng Y
The Journal of cell biology 2015 Oct 12;211(1):7-18
The Journal of cell biology 2015 Oct 12;211(1):7-18
FOXL2 down-regulates vitellogenin expression at mature stage in Eriocheir sinensis.
Li Q, Xie J, He L, Wang Y, Yang H, Duan Z, Wang Q
Bioscience reports 2015 Oct 1;35(6)
Bioscience reports 2015 Oct 1;35(6)
G-protein-coupled receptor 137 accelerates proliferation of urinary bladder cancer cells in vitro.
Du Y, Bi W, Zhang F, Wu W, Xia S, Liu H
Biotechnology and applied biochemistry 2015 Nov-Dec;62(6):855-60
Biotechnology and applied biochemistry 2015 Nov-Dec;62(6):855-60
MiR542-3p Regulates the Epithelial-Mesenchymal Transition by Directly Targeting BMP7 in NRK52e.
Liu Z, Zhou Y, Yuan Y, Nie F, Peng R, Li Q, Lyu Z, Mao Z, Huang L, Zhou L, Li Y, Hao J, Ni D, Jin Q, Long Y, Ju P, Yu W, Liu J, Hu Y, Zhou Q
International journal of molecular sciences 2015 Nov 24;16(11):27945-55
International journal of molecular sciences 2015 Nov 24;16(11):27945-55
Phosphorylation and activation of ubiquitin-specific protease-14 by Akt regulates the ubiquitin-proteasome system.
Xu D, Shan B, Lee BH, Zhu K, Zhang T, Sun H, Liu M, Shi L, Liang W, Qian L, Xiao J, Wang L, Pan L, Finley D, Yuan J
eLife 2015 Nov 2;4:e10510
eLife 2015 Nov 2;4:e10510
Encephalomyocarditis Virus 3C Protease Relieves TRAF Family Member-associated NF-κB Activator (TANK) Inhibitory Effect on TRAF6-mediated NF-κB Signaling through Cleavage of TANK.
Huang L, Liu Q, Zhang L, Zhang Q, Hu L, Li C, Wang S, Li J, Zhang Y, Yu H, Wang Y, Zhong Z, Xiong T, Xia X, Wang X, Yu L, Deng G, Cai X, Cui S, Weng C
The Journal of biological chemistry 2015 Nov 13;290(46):27618-32
The Journal of biological chemistry 2015 Nov 13;290(46):27618-32
Co-expression of mitosis-regulating genes contributes to malignant progression and prognosis in oligodendrogliomas.
Liu Y, Hu H, Zhang C, Wang H, Zhang W, Wang Z, Li M, Zhang W, Zhou D, Jiang T
Oncotarget 2015 Nov 10;6(35):38257-69
Oncotarget 2015 Nov 10;6(35):38257-69
Dental Abnormalities Caused by Novel Compound Heterozygous CTSK Mutations.
Xue Y, Wang L, Xia D, Li Q, Gao S, Dong M, Cai T, Shi S, He L, Hu K, Mao T, Duan X
Journal of dental research 2015 May;94(5):674-81
Journal of dental research 2015 May;94(5):674-81
Vav3 oncogene is upregulated and a poor prognostic factor in breast cancer patients.
Chen X, Chen SI, Liu XA, Zhou WB, Ma RR, Chen L
Oncology letters 2015 May;9(5):2143-2148
Oncology letters 2015 May;9(5):2143-2148
Microgravity activates p38 MAPK-C/EBPβ pathway to regulate the expression of arginase and inflammatory cytokines in macrophages.
Wang C, Chen H, Luo H, Zhu L, Zhao Y, Tian H, Wang R, Shang P, Zhao Y
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2015 May;64(5):303-11
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2015 May;64(5):303-11
Mitosis. Microtubule detyrosination guides chromosomes during mitosis.
Barisic M, Silva e Sousa R, Tripathy SK, Magiera MM, Zaytsev AV, Pereira AL, Janke C, Grishchuk EL, Maiato H
Science (New York, N.Y.) 2015 May 15;348(6236):799-803
Science (New York, N.Y.) 2015 May 15;348(6236):799-803
Oxysophocarpine Ameliorates Carrageenan-induced Inflammatory Pain via Inhibiting Expressions of Prostaglandin E2 and Cytokines in Mice.
Yang Y, Li YX, Wang HL, Jin SJ, Zhou R, Qiao HQ, Du J, Wu J, Zhao CJ, Niu Y, Sun T, Yu JQ
Planta medica 2015 Jul;81(10):791-7
Planta medica 2015 Jul;81(10):791-7
HAP1 helps to regulate actin-based transport of insulin-containing granules in pancreatic β cells.
Wang Z, Peng T, Wu H, He J, Li H
Histochemistry and cell biology 2015 Jul;144(1):39-48
Histochemistry and cell biology 2015 Jul;144(1):39-48
Pigment epithelium-derived factor regulates microvascular permeability through adipose triglyceride lipase in sepsis.
He T, Hu J, Yan G, Li L, Zhang D, Zhang Q, Chen B, Huang Y
Clinical science (London, England : 1979) 2015 Jul;129(1):49-61
Clinical science (London, England : 1979) 2015 Jul;129(1):49-61
MNRR1 (formerly CHCHD2) is a bi-organellar regulator of mitochondrial metabolism.
Aras S, Bai M, Lee I, Springett R, Hüttemann M, Grossman LI
Mitochondrion 2015 Jan;20:43-51
Mitochondrion 2015 Jan;20:43-51
Proteomic profile in Perna viridis after exposed to Prorocentrum lima, a dinoflagellate producing DSP toxins.
Huang L, Zou Y, Weng HW, Li HY, Liu JS, Yang WD
Environmental pollution (Barking, Essex : 1987) 2015 Jan;196:350-7
Environmental pollution (Barking, Essex : 1987) 2015 Jan;196:350-7
DNA methylation downregulated mir-10b acts as a tumor suppressor in gastric cancer.
Li Z, Lei H, Luo M, Wang Y, Dong L, Ma Y, Liu C, Song W, Wang F, Zhang J, Shen J, Yu J
Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association 2015 Jan;18(1):43-54
Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association 2015 Jan;18(1):43-54
Toward operative in vivo fluorescence imaging of the c-Met proto-oncogene for personalization of therapy in ovarian cancer.
Liu S, Zheng Y, Volpi D, El-Kasti M, Klotz D, Tullis I, Henricks A, Campo L, Myers K, Laios A, Thomas P, Ng T, Dhar S, Becker C, Vojnovic B, Ahmed AA
Cancer 2015 Jan 15;121(2):202-13
Cancer 2015 Jan 15;121(2):202-13
Lentivirus-mediated silencing of SCIN inhibits proliferation of human lung carcinoma cells.
Liu H, Shi D, Liu T, Yu Z, Zhou C
Gene 2015 Jan 1;554(1):32-9
Gene 2015 Jan 1;554(1):32-9
Novel function of PITH domain-containing 1 as an activator of internal ribosomal entry site to enhance RUNX1 expression and promote megakaryocyte differentiation.
Lu B, Sun X, Chen Y, Jin Q, Liang Q, Liu S, Li Y, Zhou Y, Li W, Huang Z
Cellular and molecular life sciences : CMLS 2015 Feb;72(4):821-32
Cellular and molecular life sciences : CMLS 2015 Feb;72(4):821-32
Annexin A3 as a potential target for immunotherapy of liver cancer stem-like cells.
Pan QZ, Pan K, Wang QJ, Weng DS, Zhao JJ, Zheng HX, Zhang XF, Jiang SS, Lv L, Tang Y, Li YQ, He J, Liu Q, Chen CL, Zhang HX, Xia JC
Stem cells (Dayton, Ohio) 2015 Feb;33(2):354-66
Stem cells (Dayton, Ohio) 2015 Feb;33(2):354-66
Human mammary microenvironment better regulates the biology of human breast cancer in humanized mouse model.
Zheng MJ, Wang J, Xu L, Zha XM, Zhao Y, Ling LJ, Wang S
Medical oncology (Northwood, London, England) 2015 Feb;32(2):427
Medical oncology (Northwood, London, England) 2015 Feb;32(2):427
Potent effects of the total saponins from Dioscorea nipponica Makino against streptozotocin-induced type 2 diabetes mellitus in rats.
Yu H, Zheng L, Xu L, Yin L, Lin Y, Li H, Liu K, Peng J
Phytotherapy research : PTR 2015 Feb;29(2):228-40
Phytotherapy research : PTR 2015 Feb;29(2):228-40
Moesin and myosin phosphatase confine neutrophil orientation in a chemotactic gradient.
Liu X, Yang T, Suzuki K, Tsukita S, Ishii M, Zhou S, Wang G, Cao L, Qian F, Taylor S, Oh MJ, Levitan I, Ye RD, Carnegie GK, Zhao Y, Malik AB, Xu J
The Journal of experimental medicine 2015 Feb 9;212(2):267-80
The Journal of experimental medicine 2015 Feb 9;212(2):267-80
Targeting non-coding RNAs with the CRISPR/Cas9 system in human cell lines.
Ho TT, Zhou N, Huang J, Koirala P, Xu M, Fung R, Wu F, Mo YY
Nucleic acids research 2015 Feb 18;43(3):e17
Nucleic acids research 2015 Feb 18;43(3):e17
The Energy Metabolism in Caenorhabditis elegans under The Extremely Low-Frequency Electromagnetic Field Exposure.
Shi Z, Yu H, Sun Y, Yang C, Lian H, Cai P
Scientific reports 2015 Feb 16;5:8471
Scientific reports 2015 Feb 16;5:8471
Flavivirus Infection Impairs Peroxisome Biogenesis and Early Antiviral Signaling.
You J, Hou S, Malik-Soni N, Xu Z, Kumar A, Rachubinski RA, Frappier L, Hobman TC
Journal of virology 2015 Dec;89(24):12349-61
Journal of virology 2015 Dec;89(24):12349-61
Erythropoietin Protects Retinal Cells in Diabetic Rats Through Upregulating ZnT8 via Activating ERK Pathway and Inhibiting HIF-1α Expression.
Xu G, Kang D, Zhang C, Lou H, Sun C, Yang Q, Lu L, Xu GT, Zhang J, Wang F
Investigative ophthalmology & visual science 2015 Dec;56(13):8166-78
Investigative ophthalmology & visual science 2015 Dec;56(13):8166-78
Tumor necrosis factor α induces myofibroblast differentiation in human tongue cancer and promotes invasiveness and angiogenesis via secretion of stromal cell-derived factor-1.
Zhou B, Zhuang XM, Wang YY, Lin ZY, Zhang DM, Fan S, Li JS, Chen WL
Oral oncology 2015 Dec;51(12):1095-102
Oral oncology 2015 Dec;51(12):1095-102
Protection of seven dibenzocyclooctadiene lignans from Schisandra chinensis against serum and glucose deprivation injury in SH-SY5Y cells.
E Q, Tang M, Zhang X, Shi Y, Wang D, Gu Y, Li S, Liang X, Wang Z, Wang C
Cell biology international 2015 Dec;39(12):1418-24
Cell biology international 2015 Dec;39(12):1418-24
Cancer-testis antigen MAGE-C2 binds Rbx1 and inhibits ubiquitin ligase-mediated turnover of cyclin E.
Hao J, Song X, Wang J, Guo C, Li Y, Li B, Zhang Y, Yin Y
Oncotarget 2015 Dec 8;6(39):42028-39
Oncotarget 2015 Dec 8;6(39):42028-39
MicroRNA-186 induces sensitivity of ovarian cancer cells to paclitaxel and cisplatin by targeting ABCB1.
Sun KX, Jiao JW, Chen S, Liu BL, Zhao Y
Journal of ovarian research 2015 Dec 2;8:80
Journal of ovarian research 2015 Dec 2;8:80
The Mediator subunit MED23 couples H2B mono-ubiquitination to transcriptional control and cell fate determination.
Yao X, Tang Z, Fu X, Yin J, Liang Y, Li C, Li H, Tian Q, Roeder RG, Wang G
The EMBO journal 2015 Dec 2;34(23):2885-902
The EMBO journal 2015 Dec 2;34(23):2885-902
Involvement of AMPK/SIRT1 pathway in anti-allodynic effect of troxerutin in CCI-induced neuropathic pain.
Gui Y, Li A, Chen F, Zhou H, Tang Y, Chen L, Chen S, Duan S
European journal of pharmacology 2015 Dec 15;769:234-41
European journal of pharmacology 2015 Dec 15;769:234-41
miRNA-204 drives cardiomyocyte proliferation via targeting Jarid2.
Liang D, Li J, Wu Y, Zhen L, Li C, Qi M, Wang L, Deng F, Huang J, Lv F, Liu Y, Ma X, Yu Z, Zhang Y, Chen YH
International journal of cardiology 2015 Dec 15;201:38-48
International journal of cardiology 2015 Dec 15;201:38-48
Genipin inhibits NLRP3 and NLRC4 inflammasome activation via autophagy suppression.
Yu SX, Du CT, Chen W, Lei QQ, Li N, Qi S, Zhang XJ, Hu GQ, Deng XM, Han WY, Yang YJ
Scientific reports 2015 Dec 11;5:17935
Scientific reports 2015 Dec 11;5:17935
Activation of AMPK restricts coxsackievirus B3 replication by inhibiting lipid accumulation.
Xie W, Wang L, Dai Q, Yu H, He X, Xiong J, Sheng H, Zhang D, Xin R, Qi Y, Hu F, Guo S, Zhang K
Journal of molecular and cellular cardiology 2015 Aug;85:155-67
Journal of molecular and cellular cardiology 2015 Aug;85:155-67
CXCR1/2 antagonism with CXCL8/Interleukin-8 analogue CXCL8(3-72)K11R/G31P restricts lung cancer growth by inhibiting tumor cell proliferation and suppressing angiogenesis.
Khan MN, Wang B, Wei J, Zhang Y, Li Q, Luan X, Cheng JW, Gordon JR, Li F, Liu H
Oncotarget 2015 Aug 28;6(25):21315-27
Oncotarget 2015 Aug 28;6(25):21315-27
The Antiviral Effect of Baicalin on Enterovirus 71 In Vitro.
Li X, Liu Y, Wu T, Jin Y, Cheng J, Wan C, Qian W, Xing F, Shi W
Viruses 2015 Aug 19;7(8):4756-71
Viruses 2015 Aug 19;7(8):4756-71
Cdc42-Interacting Protein 4 Represses E-Cadherin Expression by Promoting β-Catenin Translocation to the Nucleus in Murine Renal Tubular Epithelial Cells.
Xu C, Zhou Q, Liu L, Liu P, Pei G, Zeng R, Han M, Xu G
International journal of molecular sciences 2015 Aug 14;16(8):19170-83
International journal of molecular sciences 2015 Aug 14;16(8):19170-83
si-RNA-mediated knockdown of PDLIM5 suppresses gastric cancer cell proliferation in vitro.
Li Y, Gao Y, Xu Y, Sun X, Song X, Ma H, Yang M
Chemical biology & drug design 2015 Apr;85(4):447-53
Chemical biology & drug design 2015 Apr;85(4):447-53
DNA methylation regulates bromodomain-containing protein 2 expression during adipocyte differentiation.
Sun R, Wu Y, Wang Y, Zang K, Wei H, Wang F, Yu M
Molecular and cellular biochemistry 2015 Apr;402(1-2):23-31
Molecular and cellular biochemistry 2015 Apr;402(1-2):23-31
Ppm1b negatively regulates necroptosis through dephosphorylating Rip3.
Chen W, Wu J, Li L, Zhang Z, Ren J, Liang Y, Chen F, Yang C, Zhou Z, Su SS, Zheng X, Zhang Z, Zhong CQ, Wan H, Xiao M, Lin X, Feng XH, Han J
Nature cell biology 2015 Apr;17(4):434-44
Nature cell biology 2015 Apr;17(4):434-44
GSK3β-Dzip1-Rab8 cascade regulates ciliogenesis after mitosis.
Zhang B, Zhang T, Wang G, Wang G, Chi W, Jiang Q, Zhang C
PLoS biology 2015 Apr;13(4):e1002129
PLoS biology 2015 Apr;13(4):e1002129
MicroRNA‑133b inhibits connective tissue growth factor in colorectal cancer and correlates with the clinical stage of the disease.
Guo Y, Li X, Lin C, Zhang Y, Hu G, Zhou J, Du J, Gao K, Gan Y, Deng H
Molecular medicine reports 2015 Apr;11(4):2805-12
Molecular medicine reports 2015 Apr;11(4):2805-12
Modification of BECN1 by ISG15 plays a crucial role in autophagy regulation by type I IFN/interferon.
Xu D, Zhang T, Xiao J, Zhu K, Wei R, Wu Z, Meng H, Li Y, Yuan J
Autophagy 2015 Apr 3;11(4):617-28
Autophagy 2015 Apr 3;11(4):617-28
The tumor suppressor role of miR-124 in osteosarcoma.
Geng S, Zhang X, Chen J, Liu X, Zhang H, Xu X, Ma Y, Li B, Zhang Y, Bi Z, Yang C
PloS one 2014;9(6):e91566
PloS one 2014;9(6):e91566
Megakaryocytic differentiation of K562 cells induced by PMA reduced the activity of respiratory chain complex IV.
Huang R, Zhao L, Chen H, Yin RH, Li CY, Zhan YQ, Zhang JH, Ge CH, Yu M, Yang XM
PloS one 2014;9(5):e96246
PloS one 2014;9(5):e96246
MicroRNA-424 is down-regulated in hepatocellular carcinoma and suppresses cell migration and invasion through c-Myb.
Yu L, Ding GF, He C, Sun L, Jiang Y, Zhu L
PloS one 2014;9(3):e91661
PloS one 2014;9(3):e91661
The self-interaction of a nodavirus replicase is enhanced by mitochondrial membrane lipids.
Qiu Y, Wang Z, Liu Y, Han Y, Miao M, Qi N, Yang J, Xia H, Li X, Qin CF, Hu Y, Zhou X
PloS one 2014;9(2):e89628
PloS one 2014;9(2):e89628
Leptin downregulates aggrecan through the p38-ADAMST pathway in human nucleus pulposus cells.
Li Z, Yu X, Liang J, Wu WK, Yu J, Shen J
PloS one 2014;9(10):e109595
PloS one 2014;9(10):e109595
MicroRNA-217 regulates WASF3 expression and suppresses tumor growth and metastasis in osteosarcoma.
Shen L, Wang P, Yang J, Li X
PloS one 2014;9(10):e109138
PloS one 2014;9(10):e109138
MicroRNA-10a is down-regulated by DNA methylation and functions as a tumor suppressor in gastric cancer cells.
Jia H, Zhang Z, Zou D, Wang B, Yan Y, Luo M, Dong L, Yin H, Gong B, Li Z, Wang F, Song W, Liu C, Ma Y, Zhang J, Zhao H, Li J, Yu J
PloS one 2014;9(1):e88057
PloS one 2014;9(1):e88057
Sox9 regulates hyperexpression of Wnt1 and Fzd1 in human osteosarcoma tissues and cells.
Liu H, Chen Y, Zhou F, Jie L, Pu L, Ju J, Li F, Dai Z, Wang X, Zhou S
International journal of clinical and experimental pathology 2014;7(8):4795-805
International journal of clinical and experimental pathology 2014;7(8):4795-805
Expression of leucine aminopeptidase 3 (LAP3) correlates with prognosis and malignant development of human hepatocellular carcinoma (HCC).
Tian SY, Chen SH, Shao BF, Cai HY, Zhou Y, Zhou YL, Xu AB
International journal of clinical and experimental pathology 2014;7(7):3752-62
International journal of clinical and experimental pathology 2014;7(7):3752-62
Cytohesin-3 is upregulated in hepatocellular carcinoma and contributes to tumor growth and vascular invasion.
Fu Y, Li J, Feng MX, Yang XM, Wang YH, Zhang YL, Qin W, Xia Q, Zhang ZG
International journal of clinical and experimental pathology 2014;7(5):2123-32
International journal of clinical and experimental pathology 2014;7(5):2123-32
SERPINA3 promotes endometrial cancer cells growth by regulating G2/M cell cycle checkpoint and apoptosis.
Yang GD, Yang XM, Lu H, Ren Y, Ma MZ, Zhu LY, Wang JH, Song WW, Zhang WM, Zhang R, Zhang ZG
International journal of clinical and experimental pathology 2014;7(4):1348-58
International journal of clinical and experimental pathology 2014;7(4):1348-58
Gemcitabine resistance in breast cancer cells regulated by PI3K/AKT-mediated cellular proliferation exerts negative feedback via the MEK/MAPK and mTOR pathways.
Yang XL, Lin FJ, Guo YJ, Shao ZM, Ou ZL
OncoTargets and therapy 2014;7:1033-42
OncoTargets and therapy 2014;7:1033-42
Distinct Orai-coupling domains in STIM1 and STIM2 define the Orai-activating site.
Wang X, Wang Y, Zhou Y, Hendron E, Mancarella S, Andrake MD, Rothberg BS, Soboloff J, Gill DL
Nature communications 2014;5:3183
Nature communications 2014;5:3183
Production of transgenic pigs over-expressing the antiviral gene Mx1.
Yan Q, Yang H, Yang D, Zhao B, Ouyang Z, Liu Z, Fan N, Ouyang H, Gu W, Lai L
Cell regeneration (London, England) 2014;3(1):11
Cell regeneration (London, England) 2014;3(1):11
Type 2 diabetes mellitus control and atherosclerosis prevention in a non-obese rat model using duodenal-jejunal bypass.
Chen X, Huang Z, Ran W, Liao G, Zha L, Wang Z
Experimental and therapeutic medicine 2014 Sep;8(3):856-862
Experimental and therapeutic medicine 2014 Sep;8(3):856-862
High density lipoprotein from patients with valvular heart disease uncouples endothelial nitric oxide synthase.
Chang FJ, Yuan HY, Hu XX, Ou ZJ, Fu L, Lin ZB, Wang ZP, Wang SM, Zhou L, Xu YQ, Wang CP, Xu Z, Zhang X, Zhang CX, Ou JS
Journal of molecular and cellular cardiology 2014 Sep;74:209-19
Journal of molecular and cellular cardiology 2014 Sep;74:209-19
Neuroprotective effect of schizandrin A on oxygen and glucose deprivation/reperfusion-induced cell injury in primary culture of rat cortical neurons.
Wang CP, Li GC, Shi YW, Zhang XC, Li JL, Wang ZW, Ding F, Liang XM
Journal of physiology and biochemistry 2014 Sep;70(3):735-47
Journal of physiology and biochemistry 2014 Sep;70(3):735-47
Altered expression of hypoxia-Inducible factor-1α participates in the epileptogenesis in animal models.
Li J, Jiang G, Chen Y, Chen L, Li Z, Wang Z, Wang X
Synapse (New York, N.Y.) 2014 Sep;68(9):402-9
Synapse (New York, N.Y.) 2014 Sep;68(9):402-9
Regulation of silicosis formation by lysophosphatidic acid and its receptors.
Cong C, Mao L, Zhang Y, Zhao Z, Xu X, Zhao J
Experimental lung research 2014 Sep;40(7):317-26
Experimental lung research 2014 Sep;40(7):317-26
MicroRNA-217 functions as a tumour suppressor gene and correlates with cell resistance to cisplatin in lung cancer.
Guo J, Feng Z, Huang Z, Wang H, Lu W
Molecules and cells 2014 Sep;37(9):664-71
Molecules and cells 2014 Sep;37(9):664-71
Regulation of COX-2 expression by miR-146a in lung cancer cells.
Cornett AL, Lutz CS
RNA (New York, N.Y.) 2014 Sep;20(9):1419-30
RNA (New York, N.Y.) 2014 Sep;20(9):1419-30
SILAC-based quantitative proteomic analysis of secretome between activated and reverted hepatic stellate cells.
Zhang H, Wu P, Chen F, Hao Y, Lao Y, Ren L, Sun L, Sun W, Wei H, Chan DW, Jiang Y, He F
Proteomics 2014 Sep;14(17-18):1977-86
Proteomics 2014 Sep;14(17-18):1977-86
Dioscin attenuates hepatic ischemia-reperfusion injury in rats through inhibition of oxidative-nitrative stress, inflammation and apoptosis.
Tao X, Wan X, Xu Y, Xu L, Qi Y, Yin L, Han X, Lin Y, Peng J
Transplantation 2014 Sep 27;98(6):604-11
Transplantation 2014 Sep 27;98(6):604-11
Hypoxia-inducible factor 1α mediates neuroprotection of hypoxic postconditioning against global cerebral ischemia.
Zhu T, Zhan L, Liang D, Hu J, Lu Z, Zhu X, Sun W, Liu L, Xu E
Journal of neuropathology and experimental neurology 2014 Oct;73(10):975-86
Journal of neuropathology and experimental neurology 2014 Oct;73(10):975-86
Nardilysin-dependent proteolysis of cell-associated VTCN1 (B7-H4) marks type 1 diabetes development.
Radichev IA, Maneva-Radicheva LV, Amatya C, Parker C, Ellefson J, Wasserfall C, Atkinson M, Burn P, Savinov AY
Diabetes 2014 Oct;63(10):3470-82
Diabetes 2014 Oct;63(10):3470-82
CKIP-1 suppresses the adipogenesis of mesenchymal stem cells by enhancing HDAC1-associated repression of C/EBPα.
Li D, Zhu H, Liang C, Li W, Xing G, Ma L, Ding L, Zhang Y, He F, Zhang L
Journal of molecular cell biology 2014 Oct;6(5):368-79
Journal of molecular cell biology 2014 Oct;6(5):368-79
Suppression of toll-like receptor 2 expression inhibits the bioactivity of human hepatocellular carcinoma.
Shi W, Su L, Li Q, Sun L, Lv J, Li J, Cheng B
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2014 Oct;35(10):9627-37
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2014 Oct;35(10):9627-37
PP242 synergizes with suberoylanilide hydroxamic acid to inhibit growth of ovarian cancer cells.
Qin Y, Zhao X, Fang Y
International journal of gynecological cancer : official journal of the International Gynecological Cancer Society 2014 Oct;24(8):1373-80
International journal of gynecological cancer : official journal of the International Gynecological Cancer Society 2014 Oct;24(8):1373-80
The involvement of CXCR7 in modulating the progression of papillary thyroid carcinoma.
Liu Z, Yang L, Teng X, Zhang H, Guan H
The Journal of surgical research 2014 Oct;191(2):379-88
The Journal of surgical research 2014 Oct;191(2):379-88
Up-regulation of hexokinase1 in the right ventricle of monocrotaline induced pulmonary hypertension.
Zhang WH, Qiu MH, Wang XJ, Sun K, Zheng Y, Jing ZC
Respiratory research 2014 Oct 8;15(1):119
Respiratory research 2014 Oct 8;15(1):119
MicroRNA-188 suppresses G1/S transition by targeting multiple cyclin/CDK complexes.
Wu J, Lv Q, He J, Zhang H, Mei X, Cui K, Huang N, Xie W, Xu N, Zhang Y
Cell communication and signaling : CCS 2014 Oct 11;12:66
Cell communication and signaling : CCS 2014 Oct 11;12:66
Elevated autocrine EDIL3 protects hepatocellular carcinoma from anoikis through RGD-mediated integrin activation.
Feng MX, Ma MZ, Fu Y, Li J, Wang T, Xue F, Zhang JJ, Qin WX, Gu JR, Zhang ZG, Xia Q
Molecular cancer 2014 Oct 1;13:226
Molecular cancer 2014 Oct 1;13:226
Down-regulation of asparagine synthetase induces cell cycle arrest and inhibits cell proliferation of breast cancer.
Yang H, He X, Zheng Y, Feng W, Xia X, Yu X, Lin Z
Chemical biology & drug design 2014 Nov;84(5):578-84
Chemical biology & drug design 2014 Nov;84(5):578-84
Rho/Rock cross-talks with transforming growth factor-β/Smad pathway participates in lung fibroblast-myofibroblast differentiation.
Ji H, Tang H, Lin H, Mao J, Gao L, Liu J, Wu T
Biomedical reports 2014 Nov;2(6):787-792
Biomedical reports 2014 Nov;2(6):787-792
TBC1D9B functions as a GTPase-activating protein for Rab11a in polarized MDCK cells.
Gallo LI, Liao Y, Ruiz WG, Clayton DR, Li M, Liu YJ, Jiang Y, Fukuda M, Apodaca G, Yin XM
Molecular biology of the cell 2014 Nov 15;25(23):3779-97
Molecular biology of the cell 2014 Nov 15;25(23):3779-97
Effects of the total saponins from Rosa laevigata Michx fruit against acetaminophen-induced liver damage in mice via induction of autophagy and suppression of inflammation and apoptosis.
Dong D, Xu L, Han X, Qi Y, Xu Y, Yin L, Liu K, Peng J
Molecules (Basel, Switzerland) 2014 May 30;19(6):7189-206
Molecules (Basel, Switzerland) 2014 May 30;19(6):7189-206
Nasopharyngeal cancer-specific therapy based on fusion peptide-functionalized lipid nanoparticles.
Luo H, Lu L, Yang F, Wang L, Yang X, Luo Q, Zhang Z
ACS nano 2014 May 27;8(5):4334-47
ACS nano 2014 May 27;8(5):4334-47
Effect of nigranoic acid on Ca²⁺ influx and its downstream signal mechanism in NGF-differentiated PC12 cells.
Yuan XX, Yang LP, Yang ZL, Xiao WL, Sun HD, Wu GS, Luo HR
Journal of ethnopharmacology 2014 May 14;153(3):725-31
Journal of ethnopharmacology 2014 May 14;153(3):725-31
Molecular characterization and expression analysis of the autophagic gene beclin 1 from the purse red common carp (Cyprinus carpio) exposed to cadmium.
Gao D, Xu Z, Kuang X, Qiao P, Liu S, Zhang L, He P, Jadwiga WS, Wang Y, Min W
Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 2014 Mar;160:15-22
Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 2014 Mar;160:15-22
miR-21 promotes human nucleus pulposus cell proliferation through PTEN/AKT signaling.
Liu H, Huang X, Liu X, Xiao S, Zhang Y, Xiang T, Shen X, Wang G, Sheng B
International journal of molecular sciences 2014 Mar 5;15(3):4007-18
International journal of molecular sciences 2014 Mar 5;15(3):4007-18
Novel function of the chromosome 7 open reading frame 41 gene to promote leukemic megakaryocyte differentiation by modulating TPA-induced signaling.
Sun X, Lu B, Hu B, Xiao W, Li W, Huang Z
Blood cancer journal 2014 Mar 28;4(3):e198
Blood cancer journal 2014 Mar 28;4(3):e198
Molecular analysis of curcumin-induced polarization of murine RAW264.7 macrophages.
Chen F, Guo N, Cao G, Zhou J, Yuan Z
Journal of cardiovascular pharmacology 2014 Jun;63(6):544-52
Journal of cardiovascular pharmacology 2014 Jun;63(6):544-52
The roles of p38 MAPK/MSK1 signaling pathway in the neuroprotection of hypoxic postconditioning against transient global cerebral ischemia in adult rats.
Zhu P, Zhan L, Zhu T, Liang D, Hu J, Sun W, Hou Q, Zhou H, Wu B, Wang Y, Xu E
Molecular neurobiology 2014 Jun;49(3):1338-49
Molecular neurobiology 2014 Jun;49(3):1338-49
MGARP regulates mouse neocortical development via mitochondrial positioning.
Jia L, Liang T, Yu X, Ma C, Zhang S
Molecular neurobiology 2014 Jun;49(3):1293-308
Molecular neurobiology 2014 Jun;49(3):1293-308
HepaCAM inhibits clear cell renal carcinoma 786-0 cell proliferation via blocking PKCε translocation from cytoplasm to plasma membrane.
Tan B, Tan J, Du H, Quan Z, Xu X, Jiang X, Luo C, Wu X
Molecular and cellular biochemistry 2014 Jun;391(1-2):95-102
Molecular and cellular biochemistry 2014 Jun;391(1-2):95-102
p16 Methylation is associated with chemosensitivity to fluorouracil in patients with advanced gastric cancer.
Wang M, Li Y, Gao J, Li Y, Zhou J, Gu L, Shen L, Deng D
Medical oncology (Northwood, London, England) 2014 Jun;31(6):988
Medical oncology (Northwood, London, England) 2014 Jun;31(6):988
Negative association of R-Ras activation and breast cancer development.
Song J, Zheng B, Bu X, Fei Y, Shi S
Oncology reports 2014 Jun;31(6):2776-84
Oncology reports 2014 Jun;31(6):2776-84
Toxoplasma gondii inhibits apoptosis via a novel STAT3-miR-17-92-Bim pathway in macrophages.
Cai Y, Chen H, Mo X, Tang Y, Xu X, Zhang A, Lun Z, Lu F, Wang Y, Shen J
Cellular signalling 2014 Jun;26(6):1204-12
Cellular signalling 2014 Jun;26(6):1204-12
Activation of JNK1/2 and p38 MAPK signaling pathways promotes enterovirus 71 infection in immature dendritic cells.
Peng H, Shi M, Zhang L, Li Y, Sun J, Zhang L, Wang X, Xu X, Zhang X, Mao Y, Ji Y, Jiang J, Shi W
BMC microbiology 2014 Jun 7;14:147
BMC microbiology 2014 Jun 7;14:147
Oxidored-nitro domain containing protein 1 (NOR1) expression suppresses slug/vimentin but not snail in nasopharyngeal carcinoma: Inhibition of EMT in vitro and in vivo in mice.
Wang W, Li X, Zhang W, Li W, Yi M, Yang J, Zeng Z, Colvin Wanshura LE, McCarthy JB, Fan S, Zheng P, Chen S, Xiang B, Li G
Cancer letters 2014 Jun 28;348(1-2):109-18
Cancer letters 2014 Jun 28;348(1-2):109-18
KIF2A silencing inhibits the proliferation and migration of breast cancer cells and correlates with unfavorable prognosis in breast cancer.
Wang J, Ma S, Ma R, Qu X, Liu W, Lv C, Zhao S, Gong Y
BMC cancer 2014 Jun 21;14:461
BMC cancer 2014 Jun 21;14:461
Mulberroside A protects against ischemic impairment in primary culture of rat cortical neurons after oxygen-glucose deprivation followed by reperfusion.
Wang CP, Zhang LZ, Li GC, Shi YW, Li JL, Zhang XC, Wang ZW, Ding F, Liang XM
Journal of neuroscience research 2014 Jul;92(7):944-54
Journal of neuroscience research 2014 Jul;92(7):944-54
LPS induced miR-181a promotes pancreatic cancer cell migration via targeting PTEN and MAP2K4.
Liu J, Xu D, Wang Q, Zheng D, Jiang X, Xu L
Digestive diseases and sciences 2014 Jul;59(7):1452-60
Digestive diseases and sciences 2014 Jul;59(7):1452-60
Regulated intramembrane proteolysis of the frontotemporal lobar degeneration risk factor, TMEM106B, by signal peptide peptidase-like 2a (SPPL2a).
Brady OA, Zhou X, Hu F
The Journal of biological chemistry 2014 Jul 11;289(28):19670-80
The Journal of biological chemistry 2014 Jul 11;289(28):19670-80
The inhibitory effect of IFN-γ on protease HTRA1 expression in rheumatoid arthritis.
Hou Y, Lin H, Zhu L, Liu Z, Hu F, Shi J, Yang T, Shi X, Guo H, Tan X, Zhang L, Wang Q, Li Z, Zhao Y
Journal of immunology (Baltimore, Md. : 1950) 2014 Jul 1;193(1):130-8
Journal of immunology (Baltimore, Md. : 1950) 2014 Jul 1;193(1):130-8
Neuroprotection by (-)-epigallocatechin-3-gallate in a rat model of stroke is mediated through inhibition of endoplasmic reticulum stress.
Yao C, Zhang J, Liu G, Chen F, Lin Y
Molecular medicine reports 2014 Jan;9(1):69-76
Molecular medicine reports 2014 Jan;9(1):69-76
Microgravity inhibition of lipopolysaccharide-induced tumor necrosis factor-α expression in macrophage cells.
Wang C, Luo H, Zhu L, Yang F, Chu Z, Tian H, Feng M, Zhao Y, Shang P
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2014 Jan;63(1):91-8
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2014 Jan;63(1):91-8
iTRAQ-based proteomic analysis of dioscin on human HCT-116 colon cancer cells.
Chen H, Xu L, Yin L, Xu Y, Han X, Qi Y, Zhao Y, Liu K, Peng J
Proteomics 2014 Jan;14(1):51-73
Proteomics 2014 Jan;14(1):51-73
Dengue virus subgenomic RNA induces apoptosis through the Bcl-2-mediated PI3k/Akt signaling pathway.
Liu Y, Liu H, Zou J, Zhang B, Yuan Z
Virology 2014 Jan 5;448:15-25
Virology 2014 Jan 5;448:15-25
Long non-coding RNA UCA1 promotes breast tumor growth by suppression of p27 (Kip1).
Huang J, Zhou N, Watabe K, Lu Z, Wu F, Xu M, Mo YY
Cell death & disease 2014 Jan 23;5(1):e1008
Cell death & disease 2014 Jan 23;5(1):e1008
High glucose induces activation of the local renin‑angiotensin system in glomerular endothelial cells.
Peng H, Xing YF, Ye ZC, Li CM, Luo PL, Li M, Lou TQ
Molecular medicine reports 2014 Feb;9(2):450-6
Molecular medicine reports 2014 Feb;9(2):450-6
Pretreatment of mice with oligonucleotide prop5 protects them from influenza virus infections.
Li K, Zhou Z, Wang YO, Liu J, Zhao HB, Yang J, Wang SQ
Viruses 2014 Feb 6;6(2):573-81
Viruses 2014 Feb 6;6(2):573-81
Akt/Ezrin Tyr353/NF-κB pathway regulates EGF-induced EMT and metastasis in tongue squamous cell carcinoma.
Wang Y, Lin Z, Sun L, Fan S, Huang Z, Zhang D, Yang Z, Li J, Chen W
British journal of cancer 2014 Feb 4;110(3):695-705
British journal of cancer 2014 Feb 4;110(3):695-705
A microtubule-associated zinc finger protein, BuGZ, regulates mitotic chromosome alignment by ensuring Bub3 stability and kinetochore targeting.
Jiang H, He X, Wang S, Jia J, Wan Y, Wang Y, Zeng R, Yates J 3rd, Zhu X, Zheng Y
Developmental cell 2014 Feb 10;28(3):268-81
Developmental cell 2014 Feb 10;28(3):268-81
An alternative splicing isoform of MITA antagonizes MITA-mediated induction of type I IFNs.
Chen H, Pei R, Zhu W, Zeng R, Wang Y, Wang Y, Lu M, Chen X
Journal of immunology (Baltimore, Md. : 1950) 2014 Feb 1;192(3):1162-70
Journal of immunology (Baltimore, Md. : 1950) 2014 Feb 1;192(3):1162-70
Protein profiling the differences between diabetic and normal mouse cumulus cells.
Jiang GJ, Ma JY, Zhang GL, Mo FF, Zhang DW, Gao SH, Li XL
Molecular reproduction and development 2014 Dec;81(12):1080-5
Molecular reproduction and development 2014 Dec;81(12):1080-5
Levofloxacin increases the effect of serum deprivation on anoikis of rat nucleus pulposus cells via Bax/Bcl-2/caspase-3 pathway.
Yang SD, Bai ZL, Zhang F, Ma L, Yang DL, Ding WY
Toxicology mechanisms and methods 2014 Dec;24(9):688-96
Toxicology mechanisms and methods 2014 Dec;24(9):688-96
Differential effects of agonistic 4-1BB (CD137) monoclonal antibody on the maturation and functions of hypoxic dendritic cells.
Shang Q, Dong Z, Liu C, Bai Y, Guo C, Zhang L, Wang Q
International immunopharmacology 2014 Dec;23(2):609-16
International immunopharmacology 2014 Dec;23(2):609-16
Effects of sodium fluoride treatment in vitro on cell proliferation, BMP-2 and BMP-3 expression in human osteosarcoma MG-63 cells.
Wei Y, Wu Y, Zeng B, Zhang H
Biological trace element research 2014 Dec;162(1-3):18-25
Biological trace element research 2014 Dec;162(1-3):18-25
A recessive variant of XRCC4 predisposes to non- BRCA1/2 breast cancer in chinese women and impairs the DNA damage response via dysregulated nuclear localization.
He M, Hu X, Chen L, Cao AY, Yu KD, Shi TY, Kuang XY, Shi WB, Ling H, Li S, Qiao F, Yao L, Wei Q, Di GH, Shao ZM
Oncotarget 2014 Dec 15;5(23):12218-32
Oncotarget 2014 Dec 15;5(23):12218-32
Calreticulin promotes migration and invasion of esophageal cancer cells by upregulating neuropilin-1 expression via STAT5A.
Shi F, Shang L, Pan BQ, Wang XM, Jiang YY, Hao JJ, Zhang Y, Cai Y, Xu X, Zhan QM, Wang MR
Clinical cancer research : an official journal of the American Association for Cancer Research 2014 Dec 1;20(23):6153-62
Clinical cancer research : an official journal of the American Association for Cancer Research 2014 Dec 1;20(23):6153-62
Decreased expression of TRIM3 is associated with poor prognosis in patients with primary hepatocellular carcinoma.
Chao J, Zhang XF, Pan QZ, Zhao JJ, Jiang SS, Wang Y, Zhang JH, Xia JC
Medical oncology (Northwood, London, England) 2014 Aug;31(8):102
Medical oncology (Northwood, London, England) 2014 Aug;31(8):102
Potent effects of flavonoid-rich extract from Rosa laevigata Michx fruit against hydrogen peroxide-induced damage in PC12 cells via attenuation of oxidative stress, inflammation and apoptosis.
Liu M, Xu Y, Han X, Liang C, Yin L, Xu L, Qi Y, Zhao Y, Peng J, Sun C
Molecules (Basel, Switzerland) 2014 Aug 7;19(8):11816-32
Molecules (Basel, Switzerland) 2014 Aug 7;19(8):11816-32
microRNA 490-3P enhances the drug-resistance of human ovarian cancer cells.
Chen S, Chen X, Xiu YL, Sun KX, Zong ZH, Zhao Y
Journal of ovarian research 2014 Aug 31;7:84
Journal of ovarian research 2014 Aug 31;7:84
DNA methylation-mediated silencing of matricellular protein dermatopontin promotes hepatocellular carcinoma metastasis by α3β1 integrin-Rho GTPase signaling.
Fu Y, Feng MX, Yu J, Ma MZ, Liu XJ, Li J, Yang XM, Wang YH, Zhang YL, Ao JP, Xue F, Qin W, Gu J, Xia Q, Zhang ZG
Oncotarget 2014 Aug 30;5(16):6701-15
Oncotarget 2014 Aug 30;5(16):6701-15
Oxidoreductase activity is necessary for N-glycosylation of cysteine-proximal acceptor sites in glycoproteins.
Cherepanova NA, Shrimal S, Gilmore R
The Journal of cell biology 2014 Aug 18;206(4):525-39
The Journal of cell biology 2014 Aug 18;206(4):525-39
Puerarin protected the brain from cerebral ischemia injury via astrocyte apoptosis inhibition.
Wang N, Zhang Y, Wu L, Wang Y, Cao Y, He L, Li X, Zhao J
Neuropharmacology 2014 Apr;79:282-9
Neuropharmacology 2014 Apr;79:282-9
The role of SIRT6 in the differentiation of vascular smooth muscle cells in response to cyclic strain.
Yao QP, Zhang P, Qi YX, Chen SG, Shen BR, Han Y, Yan ZQ, Jiang ZL
The international journal of biochemistry & cell biology 2014 Apr;49:98-104
The international journal of biochemistry & cell biology 2014 Apr;49:98-104
A synergic role of caspase-6 and caspase-3 in Tau truncation at D421 induced by H2O 2.
Zhao H, Zhao W, Lok K, Wang Z, Yin M
Cellular and molecular neurobiology 2014 Apr;34(3):369-78
Cellular and molecular neurobiology 2014 Apr;34(3):369-78
Protective effects of the total saponins from Dioscorea nipponica Makino against carbon tetrachloride-induced liver injury in mice through suppression of apoptosis and inflammation.
Yu H, Zheng L, Yin L, Xu L, Qi Y, Han X, Xu Y, Liu K, Peng J
International immunopharmacology 2014 Apr;19(2):233-44
International immunopharmacology 2014 Apr;19(2):233-44
Sine oculis homeobox homolog 1 promotes α5β1-mediated invasive migration and metastasis of cervical cancer cells.
Liu D, Zhang XX, Wan DY, Xi BX, Ma D, Wang H, Gao QL
Biochemical and biophysical research communications 2014 Apr 4;446(2):549-54
Biochemical and biophysical research communications 2014 Apr 4;446(2):549-54
Umbilical cord blood cells regulate the differentiation of endogenous neural stem cells in hypoxic ischemic neonatal rats via the hedgehog signaling pathway.
Wang X, Zhao Y, Wang X
Brain research 2014 Apr 29;1560:18-26
Brain research 2014 Apr 29;1560:18-26
IKKα restoration via EZH2 suppression induces nasopharyngeal carcinoma differentiation.
Yan M, Zhang Y, He B, Xiang J, Wang ZF, Zheng FM, Xu J, Chen MY, Zhu YL, Wen HJ, Wan XB, Yue CF, Yang N, Zhang W, Zhang JL, Wang J, Wang Y, Li LH, Zeng YX, Lam EW, Hung MC, Liu Q
Nature communications 2014 Apr 17;5:3661
Nature communications 2014 Apr 17;5:3661
Cadmium induces liver cell apoptosis through caspase-3A activation in purse red common carp (Cyprinus carpio).
Gao D, Xu Z, Qiao P, Liu S, Zhang L, He P, Zhang X, Wang Y, Min W
PloS one 2013;8(12):e83423
PloS one 2013;8(12):e83423
MicroRNA-10b promotes nucleus pulposus cell proliferation through RhoC-Akt pathway by targeting HOXD10 in intervetebral disc degeneration.
Yu X, Li Z, Shen J, Wu WK, Liang J, Weng X, Qiu G
PloS one 2013;8(12):e83080
PloS one 2013;8(12):e83080
Simvastatin alleviates hyperpermeability of glomerular endothelial cells in early-stage diabetic nephropathy by inhibition of RhoA/ROCK1.
Peng H, Luo P, Li Y, Wang C, Liu X, Ye Z, Li C, Lou T
PloS one 2013;8(11):e80009
PloS one 2013;8(11):e80009
Identification of three antiviral inhibitors against Japanese encephalitis virus from library of pharmacologically active compounds 1280.
Fang J, Sun L, Peng G, Xu J, Zhou R, Cao S, Chen H, Song Y
PloS one 2013;8(11):e78425
PloS one 2013;8(11):e78425
Resolvin D1 reverts lipopolysaccharide-induced TJ proteins disruption and the increase of cellular permeability by regulating IκBα signaling in human vascular endothelial cells.
Zhang X, Wang T, Gui P, Yao C, Sun W, Wang L, Wang H, Xie W, Yao S, Lin Y, Wu Q
Oxidative medicine and cellular longevity 2013;2013:185715
Oxidative medicine and cellular longevity 2013;2013:185715
Anti-miRNA-23a oligonucleotide suppresses glioma cells growth by targeting apoptotic protease activating factor-1.
Lian S, Shi R, Bai T, Liu Y, Miao W, Wang H, Liu X, Fan Y
Current pharmaceutical design 2013;19(35):6382-9
Current pharmaceutical design 2013;19(35):6382-9
Proteomic studies of multiple myeloma in RPMI8226 cell line treated with bendamustine.
Sun C, Li J, Gu J, Liu J, Huang B
Journal of B.U.ON. : official journal of the Balkan Union of Oncology 2013 Oct-Dec;18(4):996-1005
Journal of B.U.ON. : official journal of the Balkan Union of Oncology 2013 Oct-Dec;18(4):996-1005
Differential roles of C-terminal Eps15 homology domain proteins as vesiculators and tubulators of recycling endosomes.
Cai B, Giridharan SSP, Zhang J, Saxena S, Bahl K, Schmidt JA, Sorgen PL, Guo W, Naslavsky N, Caplan S
The Journal of biological chemistry 2013 Oct 18;288(42):30172-30180
The Journal of biological chemistry 2013 Oct 18;288(42):30172-30180
Molecular cloning, immunohistochemical localization, characterization and expression analysis of caspase-9 from the purse red common carp (Cyprinus carpio) exposed to cadmium.
Gao D, Xu Z, Zhang X, Wang H, Wang Y, Min W
Aquatic toxicology (Amsterdam, Netherlands) 2013 Oct 15;142-143:53-62
Aquatic toxicology (Amsterdam, Netherlands) 2013 Oct 15;142-143:53-62
Lipopolysaccharide increases the incidence of collagen-induced arthritis in mice through induction of protease HTRA-1 expression.
Hou Y, Lin H, Zhu L, Liu Z, Hu F, Shi J, Yang T, Shi X, Zhu M, Godley BF, Wang Q, Li Z, Zhao Y
Arthritis and rheumatism 2013 Nov;65(11):2835-46
Arthritis and rheumatism 2013 Nov;65(11):2835-46
Effects of perchlorate on BDE-47-induced alteration thyroid hormone and gene expression of in the hypothalamus-pituitary-thyroid axis in zebrafish larvae.
Zhao X, Wang S, Li D, You H, Ren X
Environmental toxicology and pharmacology 2013 Nov;36(3):1176-85
Environmental toxicology and pharmacology 2013 Nov;36(3):1176-85
MicroRNA-124 mediates the cholinergic anti-inflammatory action through inhibiting the production of pro-inflammatory cytokines.
Sun Y, Li Q, Gui H, Xu DP, Yang YL, Su DF, Liu X
Cell research 2013 Nov;23(11):1270-83
Cell research 2013 Nov;23(11):1270-83
Synergistic anti-glioma effect of Hydroxygenkwanin and Apigenin in vitro.
Wang Y, Xu YS, Yin LH, Xu LN, Peng JY, Zhou H, Kang W
Chemico-biological interactions 2013 Nov 25;206(2):346-55
Chemico-biological interactions 2013 Nov 25;206(2):346-55
Amyloid-β(1-42) oligomer accelerates senescence in adult hippocampal neural stem/progenitor cells via formylpeptide receptor 2.
He N, Jin WL, Lok KH, Wang Y, Yin M, Wang ZJ
Cell death & disease 2013 Nov 21;4(11):e924
Cell death & disease 2013 Nov 21;4(11):e924
Fructose-1,6-bisphosphatase, Malate Dehydrogenase, Isocitrate Lyase, Phosphoenolpyruvate Carboxykinase, Glyceraldehyde-3-phosphate Dehydrogenase, and Cyclophilin A are secreted in Saccharomyces cerevisiae grown in low glucose.
Giardina BJ, Chiang HL
Communicative & integrative biology 2013 Nov 1;6(6):e27216
Communicative & integrative biology 2013 Nov 1;6(6):e27216
Protection of the flavonoid fraction from Rosa laevigata Michx fruit against carbon tetrachloride-induced acute liver injury in mice.
Zhang S, Lu B, Han X, Xu L, Qi Y, Yin L, Xu Y, Zhao Y, Liu K, Peng J
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2013 May;55:60-9
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2013 May;55:60-9
PPE38 of Mycobacterium marinum triggers the cross-talk of multiple pathways involved in the host response, as revealed by subcellular quantitative proteomics.
Wang H, Dong D, Tang S, Chen X, Gao Q
Journal of proteome research 2013 May 3;12(5):2055-66
Journal of proteome research 2013 May 3;12(5):2055-66
Inositol-requiring protein 1α signaling pathway is activated in the temporal cortex of patients with mesial temporal lobe epilepsy.
Liu GL, Wang KY, Guo H, Zhao SJ, Shen Y, Zhao YB
Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology 2013 Mar;34(3):357-64
Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology 2013 Mar;34(3):357-64
Salidroside protects against hydrogen peroxide-induced injury in HUVECs via the regulation of REDD1 and mTOR activation.
Xu MC, Shi HM, Wang H, Gao XF
Molecular medicine reports 2013 Jul;8(1):147-53
Molecular medicine reports 2013 Jul;8(1):147-53
c-Src regulates cell cycle proteins expression through protein kinase B/glycogen synthase kinase 3 beta and extracellular signal-regulated kinases 1/2 pathways in MCF-7 cells.
Liu X, Du L, Feng R
Acta biochimica et biophysica Sinica 2013 Jul;45(7):586-92
Acta biochimica et biophysica Sinica 2013 Jul;45(7):586-92
Identification of STAT2 serine 287 as a novel regulatory phosphorylation site in type I interferon-induced cellular responses.
Steen HC, Nogusa S, Thapa RJ, Basagoudanavar SH, Gill AL, Merali S, Barrero CA, Balachandran S, Gamero AM
The Journal of biological chemistry 2013 Jan 4;288(1):747-58
The Journal of biological chemistry 2013 Jan 4;288(1):747-58
INMAP, a novel truncated version of POLR3B, represses AP-1 and p53 transcriptional activity.
Yunlei Z, Zhe C, Yan L, Pengcheng W, Yanbo Z, Le S, Qianjin L
Molecular and cellular biochemistry 2013 Feb;374(1-2):81-9
Molecular and cellular biochemistry 2013 Feb;374(1-2):81-9
Hyperforin attenuates brain damage induced by transient middle cerebral artery occlusion (MCAO) in rats via inhibition of TRPC6 channels degradation.
Lin Y, Zhang JC, Fu J, Chen F, Wang J, Wu ZL, Yuan SY
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2013 Feb;33(2):253-62
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2013 Feb;33(2):253-62
PES1 regulates sensitivity of colorectal cancer cells to anticancer drugs.
Xie W, Qu L, Meng L, Liu C, Wu J, Shou C
Biochemical and biophysical research communications 2013 Feb 15;431(3):460-5
Biochemical and biophysical research communications 2013 Feb 15;431(3):460-5
Neuroprotective effect of calcitriol on ischemic/reperfusion injury through the NR3A/CREB pathways in the rat hippocampus.
Fu J, Xue R, Gu J, Xiao Y, Zhong H, Pan X, Ran R
Molecular medicine reports 2013 Dec;8(6):1708-14
Molecular medicine reports 2013 Dec;8(6):1708-14
Isoquercetin protects cortical neurons from oxygen-glucose deprivation-reperfusion induced injury via suppression of TLR4-NF-кB signal pathway.
Wang CP, Li JL, Zhang LZ, Zhang XC, Yu S, Liang XM, Ding F, Wang ZW
Neurochemistry international 2013 Dec;63(8):741-9
Neurochemistry international 2013 Dec;63(8):741-9
Cadmium triggers kidney cell apoptosis of purse red common carp (Cyprinus carpio) without caspase-8 activation.
Gao D, Xu Z, Zhang X, Zhu C, Wang Y, Min W
Developmental and comparative immunology 2013 Dec;41(4):728-37
Developmental and comparative immunology 2013 Dec;41(4):728-37
STAT3-dependent transactivation of miRNA genes following Toxoplasma gondii infection in macrophage.
Cai Y, Chen H, Jin L, You Y, Shen J
Parasites & vectors 2013 Dec 16;6:356
Parasites & vectors 2013 Dec 16;6:356
miR-133b, a muscle-specific microRNA, is a novel prognostic marker that participates in the progression of human colorectal cancer via regulation of CXCR4 expression.
Duan FT, Qian F, Fang K, Lin KY, Wang WT, Chen YQ
Molecular cancer 2013 Dec 13;12:164
Molecular cancer 2013 Dec 13;12:164
Effects of flavonoids from Rosa laevigata Michx fruit against high-fat diet-induced non-alcoholic fatty liver disease in rats.
Zhang S, Zheng L, Dong D, Xu L, Yin L, Qi Y, Han X, Lin Y, Liu K, Peng J
Food chemistry 2013 Dec 1;141(3):2108-16
Food chemistry 2013 Dec 1;141(3):2108-16
Neuroprotectin D1 attenuates brain damage induced by transient middle cerebral artery occlusion in rats through TRPC6/CREB pathways.
Yao C, Zhang J, Chen F, Lin Y
Molecular medicine reports 2013 Aug;8(2):543-50
Molecular medicine reports 2013 Aug;8(2):543-50
Induction of apoptosis in infantile hemangioma endothelial cells by propranolol.
Tu JB, Ma RZ, Dong Q, Jiang F, Hu XY, Li QY, Pattar P, Zhang H
Experimental and therapeutic medicine 2013 Aug;6(2):574-578
Experimental and therapeutic medicine 2013 Aug;6(2):574-578
Lumbrokinase attenuates diabetic nephropathy through regulating extracellular matrix degradation in Streptozotocin-induced diabetic rats.
Sun H, Ge N, Shao M, Cheng X, Li Y, Li S, Shen J
Diabetes research and clinical practice 2013 Apr;100(1):85-95
Diabetes research and clinical practice 2013 Apr;100(1):85-95
Vps34p is required for the decline of extracellular fructose-1,6-bisphosphatase in the vacuole import and degradation pathway.
Alibhoy AA, Giardina BJ, Dunton DD, Chiang HL
The Journal of biological chemistry 2012 Sep 21;287(39):33080-93
The Journal of biological chemistry 2012 Sep 21;287(39):33080-93
The p16-specific reactivation and inhibition of cell migration through demethylation of CpG islands by engineered transcription factors.
Zhang B, Xiang S, Zhong Q, Yin Y, Gu L, Deng D
Human gene therapy 2012 Oct;23(10):1071-81
Human gene therapy 2012 Oct;23(10):1071-81
Phosphatase of regenerating liver-3 directly interacts with integrin β1 and regulates its phosphorylation at tyrosine 783.
Tian W, Qu L, Meng L, Liu C, Wu J, Shou C
BMC biochemistry 2012 Oct 23;13:22
BMC biochemistry 2012 Oct 23;13:22
miR-129-3p controls cilia assembly by regulating CP110 and actin dynamics.
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Nature cell biology 2012 Jun 10;14(7):697-706
Nature cell biology 2012 Jun 10;14(7):697-706
Embryonic liver fodrin involved in hepatic stellate cell activation and formation of regenerative nodule in liver cirrhosis.
Wang Z, Liu F, Tu W, Chang Y, Yao J, Wu W, Jiang X, He X, Lin J, Song Y
Journal of cellular and molecular medicine 2012 Jan;16(1):118-28
Journal of cellular and molecular medicine 2012 Jan;16(1):118-28
A novel mouse model of gastric cancer with human gastric microenvironment.
Zheng MJ, Wang J, Chen YW, Xu L, Xue DD, Fu W, Zhang YF, Du Q, Zhao Y, Ling LJ, Ding Q, Liu XA, Zha XM, Zheng W, Xia TS, Wang S
Cancer letters 2012 Dec 1;325(1):108-15
Cancer letters 2012 Dec 1;325(1):108-15
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Wang Z, Song Y, Tu W, He X, Lin J, Liu F
Liver international : official journal of the International Association for the Study of the Liver 2012 Aug;32(7):1103-11
Liver international : official journal of the International Association for the Study of the Liver 2012 Aug;32(7):1103-11
Genetic and epigenetic control of UNC5C expression in human renal cell carcinoma.
Lv D, Zhao W, Dong D, Qian XP, Zhang Y, Tian XJ, Zhang J
European journal of cancer (Oxford, England : 1990) 2011 Sep;47(13):2068-76
European journal of cancer (Oxford, England : 1990) 2011 Sep;47(13):2068-76
SCFFBXL¹⁵ regulates BMP signalling by directing the degradation of HECT-type ubiquitin ligase Smurf1.
Cui Y, He S, Xing C, Lu K, Wang J, Xing G, Meng A, Jia S, He F, Zhang L
The EMBO journal 2011 May 13;30(13):2675-89
The EMBO journal 2011 May 13;30(13):2675-89
Transplanted olfactory ensheathing cells reduce the gliotic injury response of Müller cells in a rat model of retinitis pigmentosa.
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Brain research 2011 Mar 25;1382:238-44
Differentiation of human bone marrow mesenchymal stem cells into neuron-like cells in vitro.
Zeng R, Wang LW, Hu ZB, Guo WT, Wei JS, Lin H, Sun X, Chen LX, Yang LJ
Spine 2011 Jun;36(13):997-1005
Spine 2011 Jun;36(13):997-1005
Fabp3 inhibits proliferation and promotes apoptosis of embryonic myocardial cells.
Zhu C, Hu DL, Liu YQ, Zhang QJ, Chen FK, Kong XQ, Cao KJ, Zhang JS, Qian LM
Cell biochemistry and biophysics 2011 Jul;60(3):259-66
Cell biochemistry and biophysics 2011 Jul;60(3):259-66
Differential expression of microRNAs in cardiac myocytes compared to undifferentiated P19 cells.
Hu DL, Liu YQ, Chen FK, Sheng YH, Yang R, Kong XQ, Cao KJ, Zhang JS, Qian LM
International journal of molecular medicine 2011 Jul;28(1):59-64
International journal of molecular medicine 2011 Jul;28(1):59-64
Involvement of IRE1α signaling in the hippocampus in patients with mesial temporal lobe epilepsy.
Liu G, Guo H, Guo C, Zhao S, Gong D, Zhao Y
Brain research bulletin 2011 Jan 15;84(1):94-102
Brain research bulletin 2011 Jan 15;84(1):94-102
Differential proteome analysis of bone marrow mesenchymal stem cells from adolescent idiopathic scoliosis patients.
Zhuang Q, Li J, Wu Z, Zhang J, Sun W, Li T, Yan Y, Jiang Y, Zhao RC, Qiu G
PloS one 2011 Apr 22;6(4):e18834
PloS one 2011 Apr 22;6(4):e18834
Functional characterization of inward rectifier potassium ion channel in murine fetal ventricular cardiomyocytes.
Liu A, Tang M, Xi J, Gao L, Zheng Y, Luo H, Hu X, Zhao F, Reppel M, Hescheler J, Liang H
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Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2010;26(3):413-20
Alpha1,3 fucosyltransferase VII plays a role in colorectal carcinoma metastases by promoting the carbohydration of glycoprotein CD24.
Li W, Zhang W, Luo J, Cao A, Zhang Y, Huang D, Sheng W, Cai S, Li J
Oncology reports 2010 Jun;23(6):1609-17
Oncology reports 2010 Jun;23(6):1609-17
Inhibition of epithelial to mesenchymal transition in metastatic breast carcinoma cells by c-Src suppression.
Liu X, Feng R
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Acta biochimica et biophysica Sinica 2010 Jul;42(7):496-501
The role of enoyl-CoA hydratase short chain 1 and peroxiredoxin 3 in PP2-induced apoptosis in human breast cancer MCF-7 cells.
Liu X, Feng R, Du L
FEBS letters 2010 Jul 16;584(14):3185-92
FEBS letters 2010 Jul 16;584(14):3185-92
SZ-685C, a marine anthraquinone, is a potent inducer of apoptosis with anticancer activity by suppression of the Akt/FOXO pathway.
Xie G, Zhu X, Li Q, Gu M, He Z, Wu J, Li J, Lin Y, Li M, She Z, Yuan J
British journal of pharmacology 2010 Feb 1;159(3):689-97
British journal of pharmacology 2010 Feb 1;159(3):689-97
Epidermal growth factor stimulates human trophoblast cell migration through Rho A and Rho C activation.
Han J, Li L, Hu J, Yu L, Zheng Y, Guo J, Zheng X, Yi P, Zhou Y
Endocrinology 2010 Apr;151(4):1732-42
Endocrinology 2010 Apr;151(4):1732-42
Electrophysiological study on differentiation of rat bone marrow stromal stem cells into neuron-like cells in vitro by edaravone.
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Chinese journal of traumatology = Zhonghua chuang shang za zhi 2009 Jun;12(3):167-72
Chinese journal of traumatology = Zhonghua chuang shang za zhi 2009 Jun;12(3):167-72
Palladin is overexpressed in the non-neoplastic stroma of infiltrating ductal adenocarcinomas of the pancreas, but is only rarely overexpressed in neoplastic cells.
Salaria SN, Illei P, Sharma R, Walter KM, Klein AP, Eshleman JR, Maitra A, Schulick R, Winter J, Ouellette MM, Goggins M, Hruban R
Cancer biology & therapy 2007 Mar;6(3):324-8
Cancer biology & therapy 2007 Mar;6(3):324-8
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Western blot of Hela cell with anti-GAPDH (60004-1-Ig) at various dilutions.
- Sample type
- cell line
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The GAPDH antibody from Proteintech is a mouse monoclonal antibody to a recombinant protein of human GAPDH. This antibody recognizes human,mouse,rat antigen. The GAPDH antibody has been validated for the following applications: ELISA, IHC, WB, IP, IF analysis.
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunofluorescent analysis of Ethacrynic acid treated HeLa cells using 60004-1-Ig( GAPDH Antibody) at dilution of 1:50 and N/A
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- IP result of anti-GAPDH (60004-1-Ig for IP and Detection) with HeLa cell lysate.
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human breast cancer using 60004-1-Ig(GAPDH antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human breast cancer using 60004-1-Ig(GAPDH antibody) at dilution of 1:50 (under 40x lens)
- Sample type
- tissue
