Antibody data
- Antibody Data
- Antigen structure
- References [304]
- Comments [0]
- Validations
- Western blot [1]
- Immunocytochemistry [1]
- Immunoprecipitation [1]
- Immunohistochemistry [2]
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- Product number
- 11587-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#11587-1-AP, RRID:AB_2119855
- Product name
- GRP78/BIP antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated GRP78/BIP antibody (Cat. #11587-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: FC, IF, IHC, IP, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references The PERK/PKR-eIF2α Pathway Negatively Regulates Porcine Hemagglutinating Encephalomyelitis Virus Replication by Attenuating Global Protein Translation and Facilitating Stress Granule Formation.
Glucose consumption of vascular cell types in culture: toward optimization of experimental conditions.
Zinc Protects against Heat Stress-Induced Apoptosis via the Inhibition of Endoplasmic Reticulum Stress in TM3 Leydig Cells.
Eicosapentaenoic Acid-Induced Autophagy Attenuates Intervertebral Disc Degeneration by Suppressing Endoplasmic Reticulum Stress, Extracellular Matrix Degradation, and Apoptosis.
Plasma Purification Treatment Relieves the Damage of Hyperlipidemia to PBMCs.
Pharmacological Activating Transcription Factor 6 Activation Is Beneficial for Liver Retrieval With ex vivo Normothermic Mechanical Perfusion From Cardiac Dead Donor Rats.
Curcumin Alleviates Palmitic Acid-Induced LOX-1 Upregulation by Suppressing Endoplasmic Reticulum Stress in HUVECs.
Mechanosensitive Ion Channel Piezo1 Activated by Matrix Stiffness Regulates Oxidative Stress-Induced Senescence and Apoptosis in Human Intervertebral Disc Degeneration.
Wenxin Granules Regulate Endoplasmic Reticulum Stress Unfolded Protein Response and Improve Ventricular Remodeling on Rats with Myocardial Infarction.
Ginkgo Biloba Extract EGB761 Ameliorates the Extracellular Matrix Accumulation and Mesenchymal Transformation of Renal Tubules in Diabetic Kidney Disease by Inhibiting Endoplasmic Reticulum Stress.
The Dietary Supplement γ-Oryzanol Attenuates Hepatic Ischemia Reperfusion Injury via Inhibiting Endoplasmic Reticulum Stress and HMGB1/NLRP3 Inflammasome.
Endophilin A2-mediated alleviation of endoplasmic reticulum stress-induced cardiac injury involves the suppression of ERO1α/IP3R signaling pathway.
Autophagy Blockade by Ai Du Qing Formula Promotes Chemosensitivity of Breast Cancer Stem Cells Via GRP78/β-Catenin/ABCG2 Axis.
Dl-3-n-Butylphthalide Ameliorates Diabetic Nephropathy by Ameliorating Excessive Fibrosis and Podocyte Apoptosis.
Hypothermic oxygenated perfusion with defatting cocktail further improves steatotic liver grafts in a transplantation rat model.
Exosomal ERp44 derived from ER-stressed cells strengthens cisplatin resistance of nasopharyngeal carcinoma.
A rapid and simple procedure for the isolation and cultivation of fibroblast-like cells from medaka and zebrafish embryos and fin clip biopsies.
Role of UPR Sensor Activation in Cell Death-Survival Decision of Colon Cancer Cells Stressed by DPE Treatment.
Autophagy protein NRBF2 attenuates endoplasmic reticulum stress-associated neuroinflammation and oxidative stress via promoting autophagosome maturation by interacting with Rab7 after SAH.
Hydrogen sulphide reduced the accumulation of lipid droplets in cardiac tissues of db/db mice via Hrd1 S-sulfhydration.
GnRHa protects the ovarian reserve by reducing endoplasmic reticulum stress during cyclophosphamide-based chemotherapy.
Inhibition of the miR-193b-3p protects against oxidized low-density lipoprotein-induced HUVECs injury by upregulating ALDH2.
Azithromycin alleviates the severity of rheumatoid arthritis by targeting the unfolded protein response component of glucose-regulated protein 78 (GRP78).
Naringenin attenuates endoplasmic reticulum stress, reduces apoptosis, and improves functional recovery in experimental traumatic brain injury.
Targeting GRP78 enhances the sensitivity of HOS osteosarcoma cells to pyropheophorbide-α methyl ester-mediated photodynamic therapy via the Wnt/β-catenin signaling pathway.
Cytotoxic BODIPY-Appended Half-Sandwich Iridium(III) Complex Forms Protein Adducts and Induces ER Stress.
Inhibition of USP14 influences alphaherpesvirus proliferation by degrading viral VP16 protein via ER stress-triggered selective autophagy.
2-Amino-3-Methylimidazo[4,5-f]quinoline Triggering Liver Damage by Inhibiting Autophagy and Inducing Endoplasmic Reticulum Stress in Zebrafish (Danio rerio).
Contribution of Endoplasmic Reticulum Stress to the Clinical Instability of Carotid Plaques in Human Carotid Stenosis.
cFLIPL Alleviates Myocardial Ischemia-Reperfusion Injury by Inhibiting Endoplasmic Reticulum Stress.
SAA1 is transcriptionally activated by STAT3 and accelerates renal interstitial fibrosis by inducing endoplasmic reticulum stress.
The seed oil of Paeonia ludlowii ameliorates Aβ25-35-induced Alzheimer's disease in rats.
Macrophage-derived exosomes mediate silica-induced pulmonary fibrosis by activating fibroblast in an endoplasmic reticulum stress-dependent manner.
Roles of endoplasmic reticulum stress in 2,2',4,4'-tetrabromodiphenylether-induced thyroid cell apoptosis and autophagy.
SMYD3-PARP16 axis accelerates unfolded protein response and mediates neointima formation.
Heme cytotoxicity is the consequence of endoplasmic reticulum stress in atherosclerotic plaque progression.
The role of ATF6 in Cr(VI)-induced apoptosis in DF-1 cells.
Sirtuin 6 ameliorates alcohol-induced liver injury by reducing endoplasmic reticulum stress in mice.
Ubiquitin-proteasome System Is a Promising Target for Killing Cisplatin-resistant Bladder Cancer Cells.
Lipotoxicity suppresses the synthesis of growth hormone in pituitary somatotrophs via endoplasmic reticulum stress.
Characterization of a complex phenotype (fever-dependent recurrent acute liver failure and osteogenesis imperfecta) due to NBAS and P4HB variants.
Endoplasmic reticulum stress manipulates autophagic response that antagonizes polybrominated diphenyl ethers quinone induced cytotoxicity in microglial BV2 cells.
Trim21-mediated HIF-1α degradation attenuates aerobic glycolysis to inhibit renal cancer tumorigenesis and metastasis.
Neutrophil extracellular traps impair intestinal barrier functions in sepsis by regulating TLR9-mediated endoplasmic reticulum stress pathway.
The mechanism of 5-aminolevulinic acid photodynamic therapy in promoting endoplasmic reticulum stress in the treatment of HR-HPV-infected HeLa cells.
Polybrominated diphenyl ethers quinone-induced intracellular protein oxidative damage triggers ubiquitin-proteasome and autophagy-lysosomal system activation in LO2 cells.
Choline attenuates heat stress-induced oxidative injury and apoptosis in bovine mammary epithelial cells by modulating PERK/Nrf-2 signaling pathway.
Zinc Alleviates Arsenic-Induced Inflammation and Apoptosis in the Head Kidney of Common Carp by Inhibiting Oxidative Stress and Endoplasmic Reticulum Stress.
Untargeted metabolomics and transcriptomics identified glutathione metabolism disturbance and PCS and TMAO as potential biomarkers for ER stress in lung.
Thrombospondin 1-induced exosomal proteins attenuate hypoxia-induced paraptosis in corneal epithelial cells and promote wound healing.
Autophagy impairment as a key feature for acetaminophen-induced ototoxicity.
Bioactivation of clozapine by mitochondria of the murine heart: Possible cause of cardiotoxicity.
MicroRNA-150 affects endoplasmic reticulum stress via MALAT1-miR-150 axis-mediated NF-κB pathway in LPS-challenged HUVECs and septic mice.
Microcystin-leucine arginine induced the apoptosis of GnRH neurons by activating the endoplasmic reticulum stress resulting in a decrease of serum testosterone level in mice.
Activation of the G Protein-Coupled Estrogen Receptor Prevented the Development of Acute Colitis by Protecting the Crypt Cell.
Boron Attenuates Heat Stress-Induced Apoptosis by Inhibiting Endoplasmic Reticulum Stress in Mouse Granulosa Cells.
Central role of TRAP1 in the ameliorative effect of oleanolic acid on the mitochondrial-mediated and endoplasmic reticulum stress-excitated apoptosis induced by ochratoxin A.
Receptor-Mediated ER Export of Lipoproteins Controls Lipid Homeostasis in Mice and Humans.
A point mutation in the Pdia6 gene results in loss of pancreatic β-cell identity causing overt diabetes.
Endoplasmic reticulum stress pathway mediates T-2 toxin-induced chondrocyte apoptosis.
Non-canonical activation of the ER stress sensor ATF6 by Legionella pneumophila effectors.
ChREBP deficiency alleviates apoptosis by inhibiting TXNIP/oxidative stress in diabetic nephropathy.
GJB1 mutations c.212T>G and c.311A>C induce apoptosis and inwardly rectifying potassium current changes in X-linked Charcot-Marie-Tooth type 1.
ATF6-mediated unfolded protein response facilitates AAV2 transduction by releasing the suppression of AAV receptor on ER stress.
Sulforaphane protects against oxidative stress‑induced apoptosis via activating SIRT1 in mouse osteoarthritis.
The ameliorative effect of terpinen-4-ol on ER stress-induced vascular calcification depends on SIRT1-mediated regulation of PERK acetylation.
Integration of Metabolomics and Transcriptomics Reveals Ketone Body and Lipid Metabolism Disturbance Related to ER Stress in the Liver.
Manganese Mitigates Heat Stress-Induced Apoptosis by Alleviating Endoplasmic Reticulum Stress and Activating the NRF2/SOD2 Pathway in Primary Chick Embryonic Myocardial Cells.
TMEM41B acts as an ER scramblase required for lipoprotein biogenesis and lipid homeostasis.
Ultrabright plasmonic fluor nanolabel-enabled detection of a urinary ER stress biomarker in autosomal dominant tubulointerstitial kidney disease.
ARFGAP1 binds to classical swine fever virus NS5A protein and enhances CSFV replication in PK-15 cells.
Changes in hepatic triglyceride content with the activation of ER stress and increased FGF21 secretion during pregnancy.
Glutamate-Cysteine Ligase Catalytic Subunit Attenuated Hepatitis C Virus-Related Liver Fibrosis and Suppressed Endoplasmic Reticulum Stress.
Methane-Rich Saline Alleviates CA/CPR Brain Injury by Inhibiting Oxidative Stress, Microglial Activation-Induced Inflammatory Responses, and ER Stress-Mediated Apoptosis.
Therapeutic Role of Protein Tyrosine Phosphatase 1B in Parkinson's Disease via Antineuroinflammation and Neuroprotection In Vitro and In Vivo.
Diazoxide Protects against Myocardial Ischemia/Reperfusion Injury by Moderating ERS via Regulation of the miR-10a/IRE1 Pathway.
Salvianolic Acid B Improves Chronic Mild Stress-Induced Depressive Behaviors in Rats: Involvement of AMPK/SIRT1 Signaling Pathway.
Chlorin A-mediated photodynamic therapy induced apoptosis in human cholangiocarcinoma cells via impaired autophagy flux.
Role of Endoplasmic Reticulum Stress in Otitis Media.
ANKS4B Restricts Replication of Zika Virus by Downregulating the Autophagy.
Maimendong Decoction Improves Pulmonary Function in Rats With Idiopathic Pulmonary Fibrosis by Inhibiting Endoplasmic Reticulum Stress in AECIIs.
A paralog-specific role of COPI vesicles in the neuronal differentiation of mouse pluripotent cells.
Asiatic acid ameliorates acute hepatic injury by reducing endoplasmic reticulum stress and triggering hepatocyte autophagy.
Reactive oxygen species mediate anlotinib-induced apoptosis via activation of endoplasmic reticulum stress in pancreatic cancer.
Liraglutide Up-regulation Thioredoxin Attenuated Müller Cells Apoptosis in High Glucose by Regulating Oxidative Stress and Endoplasmic Reticulum Stress.
ROS-mediated PERK-eIF2α-ATF4 pathway plays an important role in arsenite-induced L-02 cells apoptosis via regulating CHOP-DR5 signaling.
Melatonin inhibits oxalate-induced endoplasmic reticulum stress and apoptosis in HK-2 cells by activating the AMPK pathway.
Neuroprotective mechanism of L-cysteine after subarachnoid hemorrhage.
T-type calcium channel blockade induces apoptosis in C2C12 myotubes and skeletal muscle via endoplasmic reticulum stress activation.
IL-32 induces epithelial-mesenchymal transition by triggering endoplasmic reticulum stress in A549 cells.
Design, synthesis, and biological evaluation of 5-((8-methoxy-2-methylquinolin-4-yl)amino)-1H-indole-2-carbohydrazide derivatives as novel Nur77 modulators.
Protective effects of pterostilbene against hepatic damage, redox imbalance, mitochondrial dysfunction, and endoplasmic reticulum stress in weanling piglets.
Aging is associated with increased TRB3, ER stress, and hepatic glucose production in the liver of rats.
Ubiquitin ligase CHIP regulates OTUD3 stability and suppresses tumour metastasis in lung cancer.
TRPV4 contributes to ER stress: Relation to apoptosis in the MPP+-induced cell model of Parkinson's disease.
Acupuncture protects against cerebral ischemia-reperfusion injury via suppressing endoplasmic reticulum stress-mediated autophagy and apoptosis.
Cleavage of cyclic AMP-responsive element-binding protein H aggravates myocardial hypoxia reperfusion injury in a hepatocyte-myocardial cell co-culture system.
Exogenous spermine attenuates rat diabetic cardiomyopathy via suppressing ROS-p53 mediated downregulation of calcium-sensitive receptor.
Pyruvate alleviates high glucose-induced endoplasmic reticulum stress and apoptosis in HK-2 cells.
Sigma-1 receptor activity in primary sensory neurons is a critical driver of neuropathic pain.
miR-384-5p promotes spinal cord injury recovery in rats through suppressing of autophagy and endoplasmic reticulum stress.
Knockout of DNase1l1l abrogates lens denucleation process and causes cataract in zebrafish.
Xanthatin induces glioma cell apoptosis and inhibits tumor growth via activating endoplasmic reticulum stress-dependent CHOP pathway.
Blockade of HSP70 by VER-155008 synergistically enhances bortezomib-induced cytotoxicity in multiple myeloma.
Intrabody against prolyl hydroxylase 2 ameliorates acetaminophen-induced acute liver injury in mice via concomitant promotion of angiogenesis and redox homeostasis.
A novel splice site indel alteration in the EIF2AK3 gene is responsible for the first cases of Wolcott-Rallison syndrome in Hungary.
A light-triggered self-reinforced nanoagent for targeted chemo-photodynamic therapy of breast cancer bone metastases via ER stress and mitochondria mediated apoptotic pathways.
Endoplasmic Reticulum Stress Signalling Induces Casein Kinase 1-Dependent Formation of Cytosolic TDP-43 Inclusions in Motor Neuron-Like Cells.
Iodine‑125 seed radiation induces ROS‑mediated apoptosis, autophagy and paraptosis in human esophageal squamous cell carcinoma cells.
Sulforaphane attenuates apoptosis of hippocampal neurons induced by high glucose via regulating endoplasmic reticulum.
Ubiquitin C-terminal hydrolase L1 (UCHL1) regulates post-myocardial infarction cardiac fibrosis through glucose-regulated protein of 78 kDa (GRP78).
UBE2T promotes glioblastoma invasion and migration via stabilizing GRP78 and regulating EMT.
Excretory/secretory products of Angiostrongylus cantonensis fifth-stage larvae induce endoplasmic reticulum stress via the Sonic hedgehog pathway in mouse astrocytes.
Perinatal low-dose PBDE-47 exposure hampered thyroglobulin turnover and induced thyroid cell apoptosis by triggering ER stress and lysosomal destabilization contributing to thyroid toxicity in adult female rats.
Polychlorinated Biphenyl Quinone Promotes Atherosclerosis through Lipid Accumulation and Endoplasmic Reticulum Stress via CD36.
Non-Esterified Fatty Acid-Induced Reactive Oxygen Species Mediated Granulosa Cells Apoptosis Is Regulated by Nrf2/p53 Signaling Pathway.
SHQ1 is an ER stress response gene that facilitates chemotherapeutics-induced apoptosis via sensitizing ER-stress response.
Circulating Exosomes From Lipopolysaccharide-Induced Ards Mice Trigger Endoplasmic Reticulum Stress in Lung Tissue.
Extracellular Vesicles Isolated from Human Induced Pluripotent Stem Cell-Derived Neurons Contain a Transcriptional Network.
Endosulfan induces endothelial inflammation and dysfunction via IRE1α/NF-κB signaling pathway.
78 kDa Glucose-Regulated Protein Attenuates Protein Aggregation and Monocyte Adhesion Induced by Angiotensin II in Vascular Cells.
Liraglutide protects pancreatic β cells from endoplasmic reticulum stress by upregulating MANF to promote autophagy turnover.
Withaferin A triggers G2/M arrest and intrinsic apoptosis in glioblastoma cells via ATF4-ATF3-CHOP axis.
Selenium Attenuates Chronic Heat Stress-Induced Apoptosis via the Inhibition of Endoplasmic Reticulum Stress in Mouse Granulosa Cells.
MCP-1 mediates ischemia-reperfusion-induced cardiomyocyte apoptosis via MCPIP1 and CaSR.
Hydrogen sulfide regulates muscle RING finger-1 protein S-sulfhydration at Cys(44) to prevent cardiac structural damage in diabetic cardiomyopathy.
Protective effect of Liraglutide on diabetic retinal neurodegeneration via inhibiting oxidative stress and endoplasmic reticulum stress.
Clinicopathological significance of endoplasmic reticulum stress proteins in ovarian carcinoma.
Oxidative Stress and Endoplasmic Reticulum Stress Are Involved in the Protective Effect of Alpha Lipoic Acid Against Heat Damage in Chicken Testes.
Protection of retinal function and morphology in MNU-induced retinitis pigmentosa rats by ALDH2: an in-vivo study.
Hepatic DNAJB9 Drives Anabolic Biasing to Reduce Steatosis and Obesity.
Fengbaisan suppresses endoplasmic reticulum stress by up-regulating SIRT1 expression to protect rats with chronic obstructive pulmonary diseases.
NLRP3 inflammasome and endoplasmic reticulum stress in the epileptogenic zone in temporal lobe epilepsy: molecular insights into their interdependence.
Zinc application alleviates the adverse renal effects of arsenic stress in a protein quality control way in common carp.
Exogenous hydrogen sulfide inhibits apoptosis by regulating endoplasmic reticulum stress-autophagy axis and improves myocardial reconstruction after acute myocardial infarction.
ALDH2 protects naturally aged mouse retina via inhibiting oxidative stress-related apoptosis and enhancing unfolded protein response in endoplasmic reticulum.
Cell cycle exit during bortezomib-induced osteogenic differentiation of mesenchymal stem cells was mediated by Xbp1s-upregulated p21Cip1 and p27Kip1.
Hydrogen sulphide ameliorating skeletal muscle atrophy in db/db mice via Muscle RING finger 1 S-sulfhydration.
Proteomic Analysis Reveals Proteins and Pathways Associated with Lactation in Bovine Mammary Epithelial Cell-Derived Exosomes.
FGF21 mitigates atherosclerosis via inhibition of NLRP3 inflammasome-mediated vascular endothelial cells pyroptosis.
LncRNA GUARDIN suppresses cellular senescence through a LRP130-PGC1α-FOXO4-p21-dependent signaling axis.
CACNA1H downregulation induces skeletal muscle atrophy involving endoplasmic reticulum stress activation and autophagy flux blockade.
Exosomes from mesenchymal stem cells modulate endoplasmic reticulum stress to protect against nucleus pulposus cell death and ameliorate intervertebral disc degeneration in vivo.
GRP78 regulates milk biosynthesis and the proliferation of bovinemammaryepithelial cells through the mTOR signaling pathway.
Unfolded Protein Response Pathways Correlatively Modulate Endoplasmic Reticulum Stress Responses in Rat Retinal Müller Cells.
Betulinic Acid Suppresses Breast Cancer Metastasis by Targeting GRP78-Mediated Glycolysis and ER Stress Apoptotic Pathway.
UFL1 Alleviates Lipopolysaccharide-Induced Cell Damage and Inflammation via Regulation of the TLR4/NF-κB Pathway in Bovine Mammary Epithelial Cells.
ZYZ-803 Mitigates Endoplasmic Reticulum Stress-Related Necroptosis after Acute Myocardial Infarction through Downregulating the RIP3-CaMKII Signaling Pathway.
Alpha-mangostin induces endoplasmic reticulum stress and autophagy which count against fatty acid synthase inhibition mediated apoptosis in human breast cancer cells.
The IRE1α-XBP1 pathway function in hypoxia-induced pulmonary vascular remodeling, is upregulated by quercetin, inhibits apoptosis and partially reverses the effect of quercetin in PASMCs.
Antimetastatic Effect of Fucoidan-Sargassum against Liver Cancer Cell Invadopodia Formation via Targeting Integrin αVβ3 and Mediating αVβ3/Src/E2F1 Signaling.
Abnormal Glucose Metabolism and Insulin Resistance Are Induced via the IRE1α/XBP-1 Pathway in Subclinical Hypothyroidism.
Vildagliptin Reduces Stenosis of Injured Carotid Artery in Diabetic Mouse Through Inhibiting Vascular Smooth Muscle Cell Proliferation via ER Stress/NF-κB Pathway.
Correction to: Protective effects of dioscin against alcohol‑induced liver injury.
Regulatory role of Golgi brefeldin A resistance factor-1 in amyloid precursor protein trafficking, cleavage and Aβ formation.
Mechanisms of IFNalpha-1a-Induced Apoptosis in a Laryngeal Cancer Cell Line.
BDE-209 induces autophagy and apoptosis via IRE1α/Akt/mTOR signaling pathway in human umbilical vein endothelial cells.
Resveratrol reduces brain injury after subarachnoid hemorrhage by inhibiting oxidative stress and endoplasmic reticulum stress.
Suhuang antitussive capsule inhibits NLRP3 inflammasome activation and ameliorates pulmonary dysfunction via suppression of endoplasmic reticulum stress in cough variant asthma.
Niban protein regulates apoptosis in HK-2 cells via caspase-dependent pathway.
Lopinavir-Ritonavir Combination Induces Endoplasmic Reticulum Stress and Kills Urological Cancer Cells.
Impaired calcium homeostasis via advanced glycation end products promotes apoptosis through endoplasmic reticulum stress in human nucleus pulposus cells and exacerbates intervertebral disc degeneration in rats.
Sevoflurane modulates AQPs (1,5) expression and endoplasmic reticulum stress in mice lung with allergic airway inflammation.
Inhibiting lysine 353 oxidation of GRP78 by a hypochlorous probe targeting endoplasmic reticulum promotes autophagy in cancer cells.
ER stress activation impairs the expression of circadian clock and clock-controlled genes in NIH3T3 cells via an ATF4-dependent mechanism.
Quantitative interaction proteomics reveals differences in the interactomes of amyloid precursor protein isoforms.
Flaccidoxide-13-Acetate-Induced Apoptosis in Human Bladder Cancer Cells is through Activation of p38/JNK, Mitochondrial Dysfunction, and Endoplasmic Reticulum Stress Regulated Pathway.
ERp29 counteracts the suppression of malignancy mediated by endoplasmic reticulum stress and promotes the metastasis of colorectal cancer.
High-fat diet induces aberrant hepatic lipid secretion in blunt snout bream by activating endoplasmic reticulum stress-associated IRE1/XBP1 pathway.
Pharmacological preconditioning with the cellular stress inducer thapsigargin protects against experimental sepsis.
Low-concentration HCP1 inhibits apoptosis in vascular endothelial cells.
Quantitative proteomic analysis of deer antler stem cells as a model of mammalian organ regeneration.
A Legionella pneumophila Kinase Phosphorylates the Hsp70 Chaperone Family to Inhibit Eukaryotic Protein Synthesis.
Cyclophilin B control of lysine post-translational modifications of skin type I collagen.
Exosomes from Microglia Attenuate Photoreceptor Injury and Neovascularization in an Animal Model of Retinopathy of Prematurity.
APS could potentially activate hepatic insulin signaling in HFD-induced IR mice.
Metformin induces TPC-1 cell apoptosis through endoplasmic reticulum stress-associated pathways in vitro and in vivo.
Knockdown of TM9SF4 boosts ER stress to trigger cell death of chemoresistant breast cancer cells.
Ranolazine prevents pressure overload-induced cardiac hypertrophy and heart failure by restoring aberrant Na+ and Ca2+ handling.
Paneth cell ablation increases the small intestinal injury during acute necrotizing pancreatitis in rats.
The deubiquitylase OTUD3 stabilizes GRP78 and promotes lung tumorigenesis.
Induction of Endoplasmic Reticulum Stress by Cadmium and Its Regulation on Nrf2 Signaling Pathway in Kidneys of Rats.
Autophagy activation alleviates nonylphenol-induced apoptosis in cultured cortical neurons.
Pterostilbene exerts a protective effect via regulating tunicamycin-induced endoplasmic reticulum stress in mouse preimplantation embryos.
MiR-451a suppressing BAP31 can inhibit proliferation and increase apoptosis through inducing ER stress in colorectal cancer.
Mesencephalic astrocyte-derived neurotrophic factor (MANF) protects against Aβ toxicity via attenuating Aβ-induced endoplasmic reticulum stress.
Chronic intermittent hypoxia accelerates liver fibrosis in rats with combined hypoxia and nonalcoholic steatohepatitis via angiogenesis rather than endoplasmic reticulum stress.
Induction of the unfolded protein response (UPR) during pseudorabies virus infection.
Inhibition of CACNA1H attenuates doxorubicin-induced acute cardiotoxicity by affecting endoplasmic reticulum stress.
Signaling from mTOR to eIF2α mediates cell migration in response to the chemotherapeutic doxorubicin.
Human placenta-derived mesenchymal stem cells inhibit apoptosis of granulosa cells induced by IRE1α pathway in autoimmune POF mice.
Bone marrow mesenchymal stem cells could reduce the toxic effects of hexavalent chromium on the liver by decreasing endoplasmic reticulum stress-mediated apoptosis via SIRT1/HIF-1α signaling pathway in rats.
Proteomic analysis of retinal pigment epithelium cells after exposure to UVA radiation.
The IRE1 signaling pathway is involved in the protective effect of low-dose LPS on myocardial ischemia-reperfusion injury.
Prion Protein Protects Cancer Cells against Endoplasmic Reticulum Stress Induced Apoptosis.
Porcine Circovirus Type 2 Induces ORF3-Independent Mitochondrial Apoptosis via PERK Activation and Elevation of Cytosolic Calcium.
Differentially expressed genes of HepG2 cells treated with gecko polypeptide mixture.
Heme Induces Endoplasmic Reticulum Stress (HIER Stress) in Human Aortic Smooth Muscle Cells.
Salvianolic Acid A Attenuates Endoplasmic Reticulum Stress and Protects Against Cholestasis-Induced Liver Fibrosis via the SIRT1/HSF1 Pathway.
Impact of GADD34 on Apoptosis of Tonsillar Mononuclear Cells from IgA Nephropathy Patients by Regulating Eif2α Phosphorylation.
MnTMPyP inhibits paraquat-induced pulmonary epithelial-like cell injury by inhibiting oxidative stress.
Neuroprotective Effects of dl-3-n-Butylphthalide against Doxorubicin-Induced Neuroinflammation, Oxidative Stress, Endoplasmic Reticulum Stress, and Behavioral Changes.
Methane-Rich Saline Ameliorates Sepsis-Induced Acute Kidney Injury through Anti-Inflammation, Antioxidative, and Antiapoptosis Effects by Regulating Endoplasmic Reticulum Stress.
Palmitic Acid Downregulates Thyroglobulin (Tg), Sodium Iodide Symporter (NIS), and Thyroperoxidase (TPO) in Human Primary Thyrocytes: A Potential Mechanism by Which Lipotoxicity Affects Thyroid?
Proscillaridin A Promotes Oxidative Stress and ER Stress, Inhibits STAT3 Activation, and Induces Apoptosis in A549 Lung Adenocarcinoma Cells.
Glucagon-Like Peptide-1 Mediates the Protective Effect of the Dipeptidyl Peptidase IV Inhibitor on Renal Fibrosis via Reducing the Phenotypic Conversion of Renal Microvascular Cells in Monocrotaline-Treated Rats.
Vitamin C alters the amount of specific endoplasmic reticulum associated proteins involved in lipid metabolism in the liver of mice synthesizing a nonfunctional Werner syndrome (Wrn) mutant protein.
Amyotrophic lateral sclerosis (ALS) and Alzheimer's disease (AD) are characterised by differential activation of ER stress pathways: focus on UPR target genes.
Ticagrelor protects against AngII-induced endothelial dysfunction by alleviating endoplasmic reticulum stress.
Selenoprotein S protects against adipocyte death through mediation of the IRE1α-sXBP1 pathway.
Phosphoglucomutase 1 inhibits hepatocellular carcinoma progression by regulating glucose trafficking.
GanDouLing combined with Penicillamine improves cerebrovascular injury via PERK/eIF2α/CHOP endoplasmic reticulum stress pathway in the mouse model of Wilson's disease.
Tetrachlorobenzoquinone-Induced Nrf2 Confers Neuron-like PC12 Cells Resistance to Endoplasmic Reticulum Stress via Regulating Glutathione Synthesis and Protein Thiol Homeostasis.
Botulinum toxin B suppresses the pressure ulcer formation in cutaneous ischemia-reperfusion injury mouse model: Possible regulation of oxidative and endoplasmic reticulum stress.
A Novel Cx50 Insert Mutation from a Chinese Congenital Cataract Family Impairs Its Cellular Membrane Localization and Function.
Autophagy is a major mechanism for the dual effects of curcumin on renal cell carcinoma cells.
Bcl-2 overexpression reduces cisplatin cytotoxicity by decreasing ER-mitochondrial Ca2+ signaling in SKOV3 cells.
Effects of sevoflurane pretreatment on the apoptosis of rat H9c2 cardiomyocytes and the expression of GRP78.
Epigallocatechin-3-gallate alleviates bladder overactivity in a rat model with metabolic syndrome and ovarian hormone deficiency through mitochondria apoptosis pathways.
Advanced oxidation protein products aggravate cardiac remodeling via cardiomyocyte apoptosis in chronic kidney disease.
Serum vitamin C levels modulate the lifespan and endoplasmic reticulum stress response pathways in mice synthesizing a nonfunctional mutant WRN protein.
TRPV6 protects ER stress-induced apoptosis via ATF6α-TRPV6-JNK pathway in human embryonic stem cell-derived cardiomyocytes.
ER-localized protein-Herpud1 is a new mediator of IL-4-induced macrophage polarization and migration.
PGK1 and GRP78 overexpression correlates with clinical significance and poor prognosis in Chinese endometrial cancer patients.
Brucella induces unfolded protein response and inflammatory response via GntR in alveolar macrophages.
Excessive ER stress and the resulting autophagic flux dysfunction contribute to fluoride-induced neurotoxicity.
Young plasma reverses age-dependent alterations in hepatic function through the restoration of autophagy.
Protective Effects of Olive Leaf Extract on Acrolein-Exacerbated Myocardial Infarction via an Endoplasmic Reticulum Stress Pathway.
Asiatic acid from Potentilla chinensis alleviates non-alcoholic fatty liver by regulating endoplasmic reticulum stress and lipid metabolism.
Hepatic Mitochondrial Defects in a Nonalcoholic Fatty Liver Disease Mouse Model Are Associated with Increased Degradation of Oxidative Phosphorylation Subunits.
Perigestational exposure to low doses of PBDE-47 induces excessive ER stress, defective autophagy and the resultant apoptosis contributing to maternal thyroid toxicity.
Mini-peptide RPL41 attenuated retinal neovascularization by inducing degradation of ATF4 in oxygen-induced retinopathy mice.
CHOP induces apoptosis by affecting brain iron metabolism in rats with subarachnoid hemorrhage.
Downregulation of reticulocalbin-1 differentially facilitates apoptosis and necroptosis in human prostate cancer cells.
Hepatic loss of Lissencephaly 1 (Lis1) induces fatty liver and accelerates liver tumorigenesis in mice.
Exogenous H2S restores ischemic post-conditioning-induced cardioprotection through inhibiting endoplasmic reticulum stress in the aged cardiomyocytes.
Hydrogen Gas Attenuates Myocardial Ischemia Reperfusion Injury Independent of Postconditioning in Rats by Attenuating Endoplasmic Reticulum Stress-Induced Autophagy.
Endoplasmic Reticulum Stress Is Involved in Cochlear Cell Apoptosis in a Cisplatin-Induced Ototoxicity Rat Model.
TBHQ Alleviated Endoplasmic Reticulum Stress-Apoptosis and Oxidative Stress by PERK-Nrf2 Crosstalk in Methamphetamine-Induced Chronic Pulmonary Toxicity.
Involvement of endoplasmic reticulum stress in formalin-induced pain is attenuated by 4-phenylbutyric acid.
GRP78 plays an integral role in tumor cell inflammation-related migration induced by M2 macrophages.
The meta and bioinformatics analysis of GRP78 expression in gastric cancer.
Inhibition of Endoplasmic Reticulum Stress Alleviates Lung Injury Induced by Brain Death.
CNPY2 is a key initiator of the PERK-CHOP pathway of the unfolded protein response.
Therapeutic effects of L-Cysteine in newborn mice subjected to hypoxia-ischemia brain injury via the CBS/H2S system: Role of oxidative stress and endoplasmic reticulum stress.
Hepatitis B virus X protein inhibits apoptosis by modulating endoplasmic reticulum stress response.
PCSK9 regulates apoptosis in human lung adenocarcinoma A549 cells via endoplasmic reticulum stress and mitochondrial signaling pathways.
Renin-angiotensin system activation accelerates atherosclerosis in experimental renal failure by promoting endoplasmic reticulum stress-related inflammation.
Calcium release induced by 2-pyridinecarboxaldehyde thiosemicarbazone and its copper complex contributes to tumor cell death.
Identification of Novel SCIRR69-Interacting Proteins During ER Stress Using SILAC-Immunoprecipitation Quantitative Proteomics Approach.
Exogenous H2S regulates endoplasmic reticulum-mitochondria cross-talk to inhibit apoptotic pathways in STZ-induced type I diabetes.
Cr(VI) induces cytotoxicity in vitro through activation of ROS-mediated endoplasmic reticulum stress and mitochondrial dysfunction via the PI3K/Akt signaling pathway.
Curcumin enhances the effects of irinotecan on colorectal cancer cells through the generation of reactive oxygen species and activation of the endoplasmic reticulum stress pathway.
Cell surface GRP78 facilitates hepatoma cells proliferation and migration by activating IGF-IR.
Endoplasmic reticulum stress and apoptosis via PERK-eIF2α-CHOP signaling in the methamphetamine-induced chronic pulmonary injury.
GALNT6 Stabilizes GRP78 Protein by O-glycosylation and Enhances its Activity to Suppress Apoptosis Under Stress Condition.
Knockdown of histidine-rich calcium-binding protein (HRC) suppresses liver fibrosis by inhibiting the activation of hepatic stellate cells.
A positive feedback loop between GRP78 and VPS34 is critical for GRP78-mediated autophagy in cancer cells.
Protective effect of mesenchymal stem cells on the pressure ulcer formation by the regulation of oxidative and endoplasmic reticulum stress.
Elevated urinary CRELD2 is associated with endoplasmic reticulum stress-mediated kidney disease.
Autoantibodies against glucose-regulated protein 78 as serological biomarkers in metastatic and recurrent hepatocellular carcinoma.
Quantitative Proteomic Profiling the Molecular Signatures of Annexin A5 in Lung Squamous Carcinoma Cells.
A Health Threat to Bystanders Living in the Homes of Smokers: How Smoke Toxins Deposited on Surfaces Can Cause Insulin Resistance.
Dysfunctional tubular endoplasmic reticulum constitutes a pathological feature of Alzheimer's disease.
Activating Transcription Factor 4 (ATF4)-ATF3-C/EBP Homologous Protein (CHOP) Cascade Shows an Essential Role in the ER Stress-Induced Sensitization of Tetrachlorobenzoquinone-Challenged PC12 Cells to ROS-Mediated Apoptosis via Death Receptor 5 (DR5) Signaling.
Hydrogen-rich saline mediates neuroprotection through the regulation of endoplasmic reticulum stress and autophagy under hypoxia-ischemia neonatal brain injury in mice.
Design, purification and assessment of GRP78 binding peptide-linked Subunit A of Subtilase cytotoxic for targeting cancer cells.
Palmitic acid aggravates inflammation of pancreatic acinar cells by enhancing unfolded protein response induced CCAAT-enhancer-binding protein β-CCAAT-enhancer-binding protein α activation.
Chronic alpha-linolenic acid treatment alleviates age-associated neuropathology: Roles of PERK/eIF2α signaling pathway.
Rifampicin-induced injury in L02 cells is alleviated by 4-PBA via inhibition of the PERK-ATF4-CHOP pathway.
Cytotoxicity of 11-epi-Sinulariolide Acetate Isolated from Cultured Soft Corals on HA22T Cells through the Endoplasmic Reticulum Stress Pathway and Mitochondrial Dysfunction.
Alpha-lipoic acid defends homocysteine-induced endoplasmic reticulum and oxidative stress in HAECs.
Cyanidin 3-O-β-Glucoside Ameliorates Ethanol-Induced Acute Liver Injury by Attenuating Oxidative Stress and Apoptosis: The Role of SIRT1/FOXO1 Signaling.
Japanese encephalitis virus induces apoptosis by the IRE1/JNK pathway of ER stress response in BHK-21 cells.
Translation from the 5' untranslated region shapes the integrated stress response.
The ATF6 pathway of the ER stress response contributes to enhanced viability in glioblastoma.
Effects of Placental Ischemia Are Attenuated by 1,25-Dihydroxyvitamin D Treatment and Associated with Reduced Apoptosis and Increased Autophagy.
ABT737 reverses cisplatin resistance by regulating ER-mitochondria Ca2+ signal transduction in human ovarian cancer cells.
Resveratrol Induces Cancer Cell Apoptosis through MiR-326/PKM2-Mediated ER Stress and Mitochondrial Fission.
Cathelicidin PR-39 peptide inhibits hypoxia/reperfusion-induced kidney cell apoptosis by suppression of the endoplasmic reticulum-stress pathway.
Endoplasmic Reticulum Stress May Play a Pivotal Role in Lipid Metabolic Disorders in a Novel Mouse Model of Subclinical Hypothyroidism.
PACE4 regulates apoptosis in human prostate cancer cells via endoplasmic reticulum stress and mitochondrial signaling pathways.
Metabolic and Phenotypic Differences between Mice Producing a Werner Syndrome Helicase Mutant Protein and Wrn Null Mice.
Impaired unfolded protein response in the degeneration of cochlea cells in a mouse model of age-related hearing loss.
IRE1 prevents endoplasmic reticulum membrane permeabilization and cell death under pathological conditions.
Polychlorinated biphenyl quinone induces endoplasmic reticulum stress, unfolded protein response, and calcium release.
Legionella suppresses the host unfolded protein response via multiple mechanisms.
Knockdown of glucose-regulated protein 78/binding immunoglobulin heavy chain protein expression by asymmetric small interfering RNA induces apoptosis in prostate cancer cells and attenuates migratory capability.
Potent effects of the total saponins from Dioscorea nipponica Makino against streptozotocin-induced type 2 diabetes mellitus in rats.
Impact of vitamin C on the cardiometabolic and inflammatory profiles of mice lacking a functional Werner syndrome protein helicase.
Ketamine-induced ulcerative cystitis and bladder apoptosis involve oxidative stress mediated by mitochondria and the endoplasmic reticulum.
Protective effects of dioscin against alcohol-induced liver injury.
The resveratrol attenuates ethanol-induced hepatocyte apoptosis via inhibiting ER-related caspase-12 activation and PDE activity in vitro.
Exposure to tributyltin induces endoplasmic reticulum stress and the unfolded protein response in zebrafish.
ABCG1 deficiency promotes endothelial apoptosis by endoplasmic reticulum stress-dependent pathway.
Protein kinase RNA-like endoplasmic reticulum kinase (PERK) signaling pathway plays a major role in reactive oxygen species (ROS)-mediated endoplasmic reticulum stress-induced apoptosis in diabetic cardiomyopathy.
The alteration of protein profile induced by cigarette smoking via oxidative stress in mice epididymis.
Upregulation of phosphorylated HSP27, PRDX2, GRP75, GRP78 and GRP94 in acquired middle ear cholesteatoma growth.
Protective effects of the total saponins from Rosa laevigata Michx fruit against carbon tetrachloride-induced acute liver injury in mice.
Selenium deficiency is associated with endoplasmic reticulum stress in a rat model of cardiac malfunction.
Cell intrinsic role of COX-2 in pancreatic cancer development.
Profiling of differentially expressed proteins in stage IV colorectal cancers with good and poor outcomes.
Proteomic analysis of anti-tumor effects of 11-dehydrosinulariolide on CAL-27 cells.
Co-chaperone HSJ1a dually regulates the proteasomal degradation of ataxin-3.
Shi J, Li Z, Xu R, Zhang J, Zhou Q, Gao R, Lu H, Lan Y, Zhao K, He H, Gao F, He W
Journal of virology 2022 Jan 12;96(1):e0169521
Journal of virology 2022 Jan 12;96(1):e0169521
Glucose consumption of vascular cell types in culture: toward optimization of experimental conditions.
Torimoto K, Okuno K, Kuroda R, Shanas N, Cicalese SM, Eguchi K, Elliott KJ, Kawai T, Corbett CB, Peluzzo AM, St Paul AK, Autieri MV, Scalia R, Rizzo V, Hashimoto T, Eguchi S
American journal of physiology. Cell physiology 2022 Jan 1;322(1):C73-C85
American journal of physiology. Cell physiology 2022 Jan 1;322(1):C73-C85
Zinc Protects against Heat Stress-Induced Apoptosis via the Inhibition of Endoplasmic Reticulum Stress in TM3 Leydig Cells.
Xiong Y, Li J, He S
Biological trace element research 2022 Feb;200(2):728-739
Biological trace element research 2022 Feb;200(2):728-739
Eicosapentaenoic Acid-Induced Autophagy Attenuates Intervertebral Disc Degeneration by Suppressing Endoplasmic Reticulum Stress, Extracellular Matrix Degradation, and Apoptosis.
Lin Z, Ni L, Teng C, Zhang Z, Wu L, Jin Y, Lu X, Lin Z
Frontiers in cell and developmental biology 2021;9:745621
Frontiers in cell and developmental biology 2021;9:745621
Plasma Purification Treatment Relieves the Damage of Hyperlipidemia to PBMCs.
Zhang XM, Gu YH, Deng H, Xu ZQ, Zhong ZY, Lyu XJ, Jin HM, Yang XH
Frontiers in cardiovascular medicine 2021;8:691336
Frontiers in cardiovascular medicine 2021;8:691336
Pharmacological Activating Transcription Factor 6 Activation Is Beneficial for Liver Retrieval With ex vivo Normothermic Mechanical Perfusion From Cardiac Dead Donor Rats.
Cheng N, Shi JH, Jin Y, Shi YB, Liu XD, Zhang HP, Cao SL, Yang H, Guo WZ, Zhang SJ
Frontiers in surgery 2021;8:665260
Frontiers in surgery 2021;8:665260
Curcumin Alleviates Palmitic Acid-Induced LOX-1 Upregulation by Suppressing Endoplasmic Reticulum Stress in HUVECs.
Luo R, Zhao L, Li S, Chen P, Wang, Yu H, Cai K, Yu Q, Tian W
BioMed research international 2021;2021:9983725
BioMed research international 2021;2021:9983725
Mechanosensitive Ion Channel Piezo1 Activated by Matrix Stiffness Regulates Oxidative Stress-Induced Senescence and Apoptosis in Human Intervertebral Disc Degeneration.
Wang B, Ke W, Wang K, Li G, Ma L, Lu S, Xiang Q, Liao Z, Luo R, Song Y, Hua W, Wu X, Zhang Y, Zeng X, Yang C
Oxidative medicine and cellular longevity 2021;2021:8884922
Oxidative medicine and cellular longevity 2021;2021:8884922
Wenxin Granules Regulate Endoplasmic Reticulum Stress Unfolded Protein Response and Improve Ventricular Remodeling on Rats with Myocardial Infarction.
Liu K, Lv M, Ji X, Lou L, Nie B, Zhao J, Wu A, Zhao M
Evidence-based complementary and alternative medicine : eCAM 2021;2021:7375549
Evidence-based complementary and alternative medicine : eCAM 2021;2021:7375549
Ginkgo Biloba Extract EGB761 Ameliorates the Extracellular Matrix Accumulation and Mesenchymal Transformation of Renal Tubules in Diabetic Kidney Disease by Inhibiting Endoplasmic Reticulum Stress.
Han J, Pang X, Shi X, Zhang Y, Peng Z, Xing Y
BioMed research international 2021;2021:6657206
BioMed research international 2021;2021:6657206
The Dietary Supplement γ-Oryzanol Attenuates Hepatic Ischemia Reperfusion Injury via Inhibiting Endoplasmic Reticulum Stress and HMGB1/NLRP3 Inflammasome.
Du Y, Zhong F, Cheng H, Li T, Chen Y, Tan P, Huang M, Liang T, Liu Y, Xia X, Fu W
Oxidative medicine and cellular longevity 2021;2021:4628050
Oxidative medicine and cellular longevity 2021;2021:4628050
Endophilin A2-mediated alleviation of endoplasmic reticulum stress-induced cardiac injury involves the suppression of ERO1α/IP3R signaling pathway.
Liu Y, Hu R, Shen H, Mo Q, Wang X, Zhang G, Li S, Liang G, Hou N, Luo J
International journal of biological sciences 2021;17(13):3672-3688
International journal of biological sciences 2021;17(13):3672-3688
Autophagy Blockade by Ai Du Qing Formula Promotes Chemosensitivity of Breast Cancer Stem Cells Via GRP78/β-Catenin/ABCG2 Axis.
Liao M, Wang C, Yang B, Huang D, Zheng Y, Wang S, Wang X, Zhang J, Tang C, Xu Z, He Y, Huang R, Zhang F, Wang Z, Wang N
Frontiers in pharmacology 2021;12:659297
Frontiers in pharmacology 2021;12:659297
Dl-3-n-Butylphthalide Ameliorates Diabetic Nephropathy by Ameliorating Excessive Fibrosis and Podocyte Apoptosis.
Xu J, Tang Z, He Y, Cai S, Wang B, Zhang S, Wu M, Qian K, Zhang K, Chai B, Chen G, Xu K, Ji H, Xiao J, Wu Y
Frontiers in pharmacology 2021;12:628950
Frontiers in pharmacology 2021;12:628950
Hypothermic oxygenated perfusion with defatting cocktail further improves steatotic liver grafts in a transplantation rat model.
Lin F, Zhen F, Yan X, Shaojun Y, Guizhu P, Yanfeng W, Qifa Y
Artificial organs 2021 Sep;45(9):E304-E316
Artificial organs 2021 Sep;45(9):E304-E316
Exosomal ERp44 derived from ER-stressed cells strengthens cisplatin resistance of nasopharyngeal carcinoma.
Xia T, Tian H, Zhang K, Zhang S, Chen W, Shi S, You Y
BMC cancer 2021 Sep 8;21(1):1003
BMC cancer 2021 Sep 8;21(1):1003
A rapid and simple procedure for the isolation and cultivation of fibroblast-like cells from medaka and zebrafish embryos and fin clip biopsies.
Beedgen L, Hüllen A, Gücüm S, Thumberger T, Wittbrodt J, Thiel C
Laboratory animals 2021 Sep 22;:236772211045483
Laboratory animals 2021 Sep 22;:236772211045483
Role of UPR Sensor Activation in Cell Death-Survival Decision of Colon Cancer Cells Stressed by DPE Treatment.
Benedetti R, Gilardini Montani MS, Romeo MA, Arena A, Santarelli R, D'Orazi G, Cirone M
Biomedicines 2021 Sep 18;9(9)
Biomedicines 2021 Sep 18;9(9)
Autophagy protein NRBF2 attenuates endoplasmic reticulum stress-associated neuroinflammation and oxidative stress via promoting autophagosome maturation by interacting with Rab7 after SAH.
Zeng H, Chen H, Li M, Zhuang J, Peng Y, Zhou H, Xu C, Yu Q, Fu X, Cao S, Cai J, Yan F, Chen G
Journal of neuroinflammation 2021 Sep 16;18(1):210
Journal of neuroinflammation 2021 Sep 16;18(1):210
Hydrogen sulphide reduced the accumulation of lipid droplets in cardiac tissues of db/db mice via Hrd1 S-sulfhydration.
Sun Y, Zhang L, Lu B, Wen J, Wang M, Zhang S, Li Q, Shu F, Lu F, Liu N, Peng S, Zhao Y, Dong S, Lu F, Zhang W, Wang Y
Journal of cellular and molecular medicine 2021 Oct;25(19):9154-9167
Journal of cellular and molecular medicine 2021 Oct;25(19):9154-9167
GnRHa protects the ovarian reserve by reducing endoplasmic reticulum stress during cyclophosphamide-based chemotherapy.
Li X, Liu S, Chen X, Huang R, Ma L, Weng H, Yu Y, Zong X
NPJ breast cancer 2021 Oct 7;7(1):132
NPJ breast cancer 2021 Oct 7;7(1):132
Inhibition of the miR-193b-3p protects against oxidized low-density lipoprotein-induced HUVECs injury by upregulating ALDH2.
Bai Y, Wang M, Yang Y, Liu X, Chen Q, Guo Z
Cell biology international 2021 Oct 31;
Cell biology international 2021 Oct 31;
Azithromycin alleviates the severity of rheumatoid arthritis by targeting the unfolded protein response component of glucose-regulated protein 78 (GRP78).
Zhang Y, Ge L, Song G, Zhang R, Li S, Shi H, Zhang H, Li Y, Pan J, Wang L, Han J
British journal of pharmacology 2021 Oct 19;
British journal of pharmacology 2021 Oct 19;
Naringenin attenuates endoplasmic reticulum stress, reduces apoptosis, and improves functional recovery in experimental traumatic brain injury.
Deng C, Yi R, Fei M, Li T, Han Y, Wang H
Brain research 2021 Oct 15;1769:147591
Brain research 2021 Oct 15;1769:147591
Targeting GRP78 enhances the sensitivity of HOS osteosarcoma cells to pyropheophorbide-α methyl ester-mediated photodynamic therapy via the Wnt/β-catenin signaling pathway.
Zuo Q, Ou Y, Zhong S, Yu H, Zhan F, Zhang M
Acta biochimica et biophysica Sinica 2021 Oct 12;53(10):1387-1397
Acta biochimica et biophysica Sinica 2021 Oct 12;53(10):1387-1397
Cytotoxic BODIPY-Appended Half-Sandwich Iridium(III) Complex Forms Protein Adducts and Induces ER Stress.
Ramos R, Gilles JF, Morichon R, Przybylski C, Caron B, Botuha C, Karaiskou A, Salmain M, Sobczak-Thépot J
Journal of medicinal chemistry 2021 Nov 25;64(22):16675-16686
Journal of medicinal chemistry 2021 Nov 25;64(22):16675-16686
Inhibition of USP14 influences alphaherpesvirus proliferation by degrading viral VP16 protein via ER stress-triggered selective autophagy.
Ming SL, Zhang S, Wang Q, Zeng L, Zhou LY, Wang MD, Ma YX, Han LQ, Zhong K, Zhu HS, Bai YL, Yang GY, Wang J, Chu BB
Autophagy 2021 Nov 25;:1-21
Autophagy 2021 Nov 25;:1-21
2-Amino-3-Methylimidazo[4,5-f]quinoline Triggering Liver Damage by Inhibiting Autophagy and Inducing Endoplasmic Reticulum Stress in Zebrafish (Danio rerio).
Li D, Li Z, Zhang T, Peng B, Zhang Y, Sun H, Wang S
Toxins 2021 Nov 22;13(11)
Toxins 2021 Nov 22;13(11)
Contribution of Endoplasmic Reticulum Stress to the Clinical Instability of Carotid Plaques in Human Carotid Stenosis.
Hosoda K, Imahori T, Tanaka K, Uno T, Nakai T, Kohta M, Fujita A, Sasayama T
Translational stroke research 2021 Nov 16;
Translational stroke research 2021 Nov 16;
cFLIPL Alleviates Myocardial Ischemia-Reperfusion Injury by Inhibiting Endoplasmic Reticulum Stress.
Li YZ, Wu H, Liu D, Yang J, Yang J, Ding JW, Zhou G, Zhang J, Zhang D
Cardiovascular drugs and therapy 2021 Nov 12;
Cardiovascular drugs and therapy 2021 Nov 12;
SAA1 is transcriptionally activated by STAT3 and accelerates renal interstitial fibrosis by inducing endoplasmic reticulum stress.
Zhang F, Zhou X, Zou H, Liu L, Li X, Ruan Y, Xie Y, Shi M, Xiao Y, Wang Y, Zhou Y, Wu Y, Guo B
Experimental cell research 2021 Nov 1;408(1):112856
Experimental cell research 2021 Nov 1;408(1):112856
The seed oil of Paeonia ludlowii ameliorates Aβ25-35-induced Alzheimer's disease in rats.
Lu YZ, Zhang CQ, Yu BX, Zhang EH, Quan H, Yin X, Cai H, Yuan F, Li LQ, Xu YJ, Su YJ, Xing YJ, Liao ZH, Lan XZ
Food science & nutrition 2021 May;9(5):2402-2413
Food science & nutrition 2021 May;9(5):2402-2413
Macrophage-derived exosomes mediate silica-induced pulmonary fibrosis by activating fibroblast in an endoplasmic reticulum stress-dependent manner.
Qin X, Lin X, Liu L, Li Y, Li X, Deng Z, Chen H, Chen H, Niu Z, Li Z, Hu Y
Journal of cellular and molecular medicine 2021 May;25(9):4466-4477
Journal of cellular and molecular medicine 2021 May;25(9):4466-4477
Roles of endoplasmic reticulum stress in 2,2',4,4'-tetrabromodiphenylether-induced thyroid cell apoptosis and autophagy.
Ma R, Li B, Zhang C, Lei R, Zhang X, Wang C, Zhang S, Wang A
Ecotoxicology and environmental safety 2021 May;214:112077
Ecotoxicology and environmental safety 2021 May;214:112077
SMYD3-PARP16 axis accelerates unfolded protein response and mediates neointima formation.
Long F, Yang D, Wang J, Wang Q, Ni T, Wei G, Zhu Y, Liu X
Acta pharmaceutica Sinica. B 2021 May;11(5):1261-1273
Acta pharmaceutica Sinica. B 2021 May;11(5):1261-1273
Heme cytotoxicity is the consequence of endoplasmic reticulum stress in atherosclerotic plaque progression.
Pethő D, Hendrik Z, Nagy A, Beke L, Patsalos A, Nagy L, Póliska S, Méhes G, Tóth C, Potor L, Eaton JW, Jacob HS, Balla G, Balla J, Gáll T
Scientific reports 2021 May 17;11(1):10435
Scientific reports 2021 May 17;11(1):10435
The role of ATF6 in Cr(VI)-induced apoptosis in DF-1 cells.
Zhang S, Zhao X, Hao J, Zhu Y, Wang Y, Wang L, Guo S, Yi H, Liu Y, Liu J
Journal of hazardous materials 2021 May 15;410:124607
Journal of hazardous materials 2021 May 15;410:124607
Sirtuin 6 ameliorates alcohol-induced liver injury by reducing endoplasmic reticulum stress in mice.
Xin Y, Xu L, Zhang X, Yang C, Wang Q, Xiong X
Biochemical and biophysical research communications 2021 Mar 12;544:44-51
Biochemical and biophysical research communications 2021 Mar 12;544:44-51
Ubiquitin-proteasome System Is a Promising Target for Killing Cisplatin-resistant Bladder Cancer Cells.
Okubo K, Isono M, Asano T, REßING N, Schulz WA, Hansen FK, Sato A
Anticancer research 2021 Jun;41(6):2901-2912
Anticancer research 2021 Jun;41(6):2901-2912
Lipotoxicity suppresses the synthesis of growth hormone in pituitary somatotrophs via endoplasmic reticulum stress.
Gong Y, Yang J, Wei S, Yang R, Gao L, Shao S, Zhao J
Journal of cellular and molecular medicine 2021 Jun;25(11):5250-5259
Journal of cellular and molecular medicine 2021 Jun;25(11):5250-5259
Characterization of a complex phenotype (fever-dependent recurrent acute liver failure and osteogenesis imperfecta) due to NBAS and P4HB variants.
Cotrina-Vinagre FJ, Rodríguez-García ME, Martín-Hernández E, Durán-Aparicio C, Merino-López A, Medina-Benítez E, Martínez-Azorín F
Molecular genetics and metabolism 2021 Jun;133(2):201-210
Molecular genetics and metabolism 2021 Jun;133(2):201-210
Endoplasmic reticulum stress manipulates autophagic response that antagonizes polybrominated diphenyl ethers quinone induced cytotoxicity in microglial BV2 cells.
Zhu Q, Liu Z, Wang Y, Song E, Song Y
Journal of hazardous materials 2021 Jun 5;411:124958
Journal of hazardous materials 2021 Jun 5;411:124958
Trim21-mediated HIF-1α degradation attenuates aerobic glycolysis to inhibit renal cancer tumorigenesis and metastasis.
Chen X, Li Z, Yong H, Wang W, Wang D, Chu S, Li M, Hou P, Zheng J, Bai J
Cancer letters 2021 Jun 28;508:115-126
Cancer letters 2021 Jun 28;508:115-126
Neutrophil extracellular traps impair intestinal barrier functions in sepsis by regulating TLR9-mediated endoplasmic reticulum stress pathway.
Sun S, Duan Z, Wang X, Chu C, Yang C, Chen F, Wang D, Wang C, Li Q, Ding W
Cell death & disease 2021 Jun 11;12(6):606
Cell death & disease 2021 Jun 11;12(6):606
The mechanism of 5-aminolevulinic acid photodynamic therapy in promoting endoplasmic reticulum stress in the treatment of HR-HPV-infected HeLa cells.
Li Z, Teng M, Wang Y, Wang Q, Feng Y, Xiao Z, Li C, Zeng K
Photodermatology, photoimmunology & photomedicine 2021 Jul;37(4):348-359
Photodermatology, photoimmunology & photomedicine 2021 Jul;37(4):348-359
Polybrominated diphenyl ethers quinone-induced intracellular protein oxidative damage triggers ubiquitin-proteasome and autophagy-lysosomal system activation in LO2 cells.
Wang Y, Xu L, Peng L, Fang C, Qin Q, Lv X, Liu Z, Yang B, Song E, Song Y
Chemosphere 2021 Jul;275:130034
Chemosphere 2021 Jul;275:130034
Choline attenuates heat stress-induced oxidative injury and apoptosis in bovine mammary epithelial cells by modulating PERK/Nrf-2 signaling pathway.
Yang M, Kuang M, Wang G, Ali I, Tang Y, Yang C, Li Y, Li L
Molecular immunology 2021 Jul;135:388-397
Molecular immunology 2021 Jul;135:388-397
Zinc Alleviates Arsenic-Induced Inflammation and Apoptosis in the Head Kidney of Common Carp by Inhibiting Oxidative Stress and Endoplasmic Reticulum Stress.
Xing P, Zhang Y, Chi Q, Li S
Biological trace element research 2021 Jul 21;
Biological trace element research 2021 Jul 21;
Untargeted metabolomics and transcriptomics identified glutathione metabolism disturbance and PCS and TMAO as potential biomarkers for ER stress in lung.
Wang Z, Ma P, Wang Y, Hou B, Zhou C, Tian H, Li B, Shui G, Yang X, Qiang G, Yin C, Du G
Scientific reports 2021 Jul 19;11(1):14680
Scientific reports 2021 Jul 19;11(1):14680
Thrombospondin 1-induced exosomal proteins attenuate hypoxia-induced paraptosis in corneal epithelial cells and promote wound healing.
Lai YH, Lee PY, Lu CY, Liu YR, Wang SC, Liu CC, Chang YC, Chen YH, Su CC, Li CY, Liu PL
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 Jan;35(1):e21200
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 Jan;35(1):e21200
Autophagy impairment as a key feature for acetaminophen-induced ototoxicity.
Zhao T, Zheng T, Yu H, Hu BH, Hu B, Ma P, Yang Y, Yang N, Hu J, Cao T, Chen G, Yan B, Peshoff M, Hatzoglou M, Geng R, Li B, Zheng QY
Cell death & disease 2021 Jan 4;12(1):3
Cell death & disease 2021 Jan 4;12(1):3
Bioactivation of clozapine by mitochondria of the murine heart: Possible cause of cardiotoxicity.
Arzuk E, Karakuş F, Orhan H
Toxicology 2021 Jan 15;447:152628
Toxicology 2021 Jan 15;447:152628
MicroRNA-150 affects endoplasmic reticulum stress via MALAT1-miR-150 axis-mediated NF-κB pathway in LPS-challenged HUVECs and septic mice.
Liu L, Yan LN, Sui Z
Life sciences 2021 Jan 15;265:118744
Life sciences 2021 Jan 15;265:118744
Microcystin-leucine arginine induced the apoptosis of GnRH neurons by activating the endoplasmic reticulum stress resulting in a decrease of serum testosterone level in mice.
Jin H, Hou J, Meng X, Ma T, Wang B, Liu Z, Sha X, Ding J, Han X
Ecotoxicology and environmental safety 2021 Jan 15;208:111748
Ecotoxicology and environmental safety 2021 Jan 15;208:111748
Activation of the G Protein-Coupled Estrogen Receptor Prevented the Development of Acute Colitis by Protecting the Crypt Cell.
Wang Q, Li Z, Liu K, Liu J, Chai S, Chen G, Wen S, Ming T, Wang J, Ma Y, Zeng H, Liu C, Xue B
The Journal of pharmacology and experimental therapeutics 2021 Feb;376(2):281-293
The Journal of pharmacology and experimental therapeutics 2021 Feb;376(2):281-293
Boron Attenuates Heat Stress-Induced Apoptosis by Inhibiting Endoplasmic Reticulum Stress in Mouse Granulosa Cells.
Xiong Y, Jin E, Yin Q, Che C, He S
Biological trace element research 2021 Feb;199(2):611-621
Biological trace element research 2021 Feb;199(2):611-621
Central role of TRAP1 in the ameliorative effect of oleanolic acid on the mitochondrial-mediated and endoplasmic reticulum stress-excitated apoptosis induced by ochratoxin A.
Zhang Q, Chen W, Zhang B, Li C, Zhang X, Wang Q, Wang Y, Zhou Q, Li X, Shen XL
Toxicology 2021 Feb 28;450:152681
Toxicology 2021 Feb 28;450:152681
Receptor-Mediated ER Export of Lipoproteins Controls Lipid Homeostasis in Mice and Humans.
Wang X, Wang H, Xu B, Huang D, Nie C, Pu L, Zajac GJM, Yan H, Zhao J, Shi F, Emmer BT, Lu J, Wang R, Dong X, Dai J, Zhou W, Wang C, Gao G, Wang Y, Willer C, Lu X, Zhu Y, Chen XW
Cell metabolism 2021 Feb 2;33(2):350-366.e7
Cell metabolism 2021 Feb 2;33(2):350-366.e7
A point mutation in the Pdia6 gene results in loss of pancreatic β-cell identity causing overt diabetes.
Chhabra NF, Amend AL, Bastidas-Ponce A, Sabrautzki S, Tarquis-Medina M, Sachs S, Rubey M, Lorenz-Depiereux B, Feuchtinger A, Bakhti M, Lickert H, Przemeck GKH, Hrabě de Angelis M
Molecular metabolism 2021 Dec;54:101334
Molecular metabolism 2021 Dec;54:101334
Endoplasmic reticulum stress pathway mediates T-2 toxin-induced chondrocyte apoptosis.
Liu YN, Mu YD, Wang H, Zhang M, Shi YW, Mi G, Peng LX, Chen JH
Toxicology 2021 Dec;464:152989
Toxicology 2021 Dec;464:152989
Non-canonical activation of the ER stress sensor ATF6 by Legionella pneumophila effectors.
Ibe NU, Subramanian A, Mukherjee S
Life science alliance 2021 Dec;4(12)
Life science alliance 2021 Dec;4(12)
ChREBP deficiency alleviates apoptosis by inhibiting TXNIP/oxidative stress in diabetic nephropathy.
Chen N, Song S, Yang Z, Wu M, Mu L, Zhou T, Shi Y
Journal of diabetes and its complications 2021 Dec;35(12):108050
Journal of diabetes and its complications 2021 Dec;35(12):108050
GJB1 mutations c.212T>G and c.311A>C induce apoptosis and inwardly rectifying potassium current changes in X-linked Charcot-Marie-Tooth type 1.
Guo H, Liu Y, Gu J, Luo J, Ma Y, Xiao F
Biochemical and biophysical research communications 2021 Dec 10;582:8-15
Biochemical and biophysical research communications 2021 Dec 10;582:8-15
ATF6-mediated unfolded protein response facilitates AAV2 transduction by releasing the suppression of AAV receptor on ER stress.
Cui M, Zhao Q, Wang J, Si Y, Cheng S, Ding W
Journal of virology 2021 Dec 1;:JVI0110321
Journal of virology 2021 Dec 1;:JVI0110321
Sulforaphane protects against oxidative stress‑induced apoptosis via activating SIRT1 in mouse osteoarthritis.
Chen M, Huang L, Lv Y, Li L, Dong Q
Molecular medicine reports 2021 Aug;24(2)
Molecular medicine reports 2021 Aug;24(2)
The ameliorative effect of terpinen-4-ol on ER stress-induced vascular calcification depends on SIRT1-mediated regulation of PERK acetylation.
Zhang Y, He L, Tu M, Huang M, Chen Y, Pan D, Peng J, Shen X
Pharmacological research 2021 Aug;170:105629
Pharmacological research 2021 Aug;170:105629
Integration of Metabolomics and Transcriptomics Reveals Ketone Body and Lipid Metabolism Disturbance Related to ER Stress in the Liver.
Ma P, Wang Z, Wang Y, Hou B, Sun J, Tian H, Li B, Shui G, Yang X, Yang X, Qiang G, Liew CW, Du G
Journal of proteome research 2021 Aug 6;20(8):3875-3888
Journal of proteome research 2021 Aug 6;20(8):3875-3888
Manganese Mitigates Heat Stress-Induced Apoptosis by Alleviating Endoplasmic Reticulum Stress and Activating the NRF2/SOD2 Pathway in Primary Chick Embryonic Myocardial Cells.
Qin S, Wang R, Tang D, Qin S, Guo Y, Shi Z
Biological trace element research 2021 Aug 4;
Biological trace element research 2021 Aug 4;
TMEM41B acts as an ER scramblase required for lipoprotein biogenesis and lipid homeostasis.
Huang D, Xu B, Liu L, Wu L, Zhu Y, Ghanbarpour A, Wang Y, Chen FJ, Lyu J, Hu Y, Kang Y, Zhou W, Wang X, Ding W, Li X, Jiang Z, Chen J, Zhang X, Zhou H, Li JZ, Guo C, Zheng W, Zhang X, Li P, Melia T, Reinisch K, Chen XW
Cell metabolism 2021 Aug 3;33(8):1655-1670.e8
Cell metabolism 2021 Aug 3;33(8):1655-1670.e8
Ultrabright plasmonic fluor nanolabel-enabled detection of a urinary ER stress biomarker in autosomal dominant tubulointerstitial kidney disease.
Kim Y, Wang Z, Li C, Kidd K, Wang Y, Johnson BG, Kmoch S, Morrissey JJ, Bleyer AJ, Duffield JS, Singamaneni S, Chen YM
American journal of physiology. Renal physiology 2021 Aug 1;321(2):F236-F244
American journal of physiology. Renal physiology 2021 Aug 1;321(2):F236-F244
ARFGAP1 binds to classical swine fever virus NS5A protein and enhances CSFV replication in PK-15 cells.
Zhang L, Jin M, Song M, Liu S, Wang T, Guo K, Zhang Y
Veterinary microbiology 2021 Apr;255:109034
Veterinary microbiology 2021 Apr;255:109034
Changes in hepatic triglyceride content with the activation of ER stress and increased FGF21 secretion during pregnancy.
Lu J, Gong Y, Wei X, Yao Z, Yang R, Xin J, Gao L, Shao S
Nutrition & metabolism 2021 Apr 13;18(1):40
Nutrition & metabolism 2021 Apr 13;18(1):40
Glutamate-Cysteine Ligase Catalytic Subunit Attenuated Hepatitis C Virus-Related Liver Fibrosis and Suppressed Endoplasmic Reticulum Stress.
Fu N, Li D, Li W, Zhao W, Zhang S, Liu L, Zhao S, Du J, Kong L, Wang R, Zhang Y, Nan Y
Frontiers in molecular biosciences 2020;7:199
Frontiers in molecular biosciences 2020;7:199
Methane-Rich Saline Alleviates CA/CPR Brain Injury by Inhibiting Oxidative Stress, Microglial Activation-Induced Inflammatory Responses, and ER Stress-Mediated Apoptosis.
Cui R, Liu S, Wang C, Liu T, Ren J, Jia Y, Tong Y, Liu C, Zhang J
Oxidative medicine and cellular longevity 2020;2020:8829328
Oxidative medicine and cellular longevity 2020;2020:8829328
Therapeutic Role of Protein Tyrosine Phosphatase 1B in Parkinson's Disease via Antineuroinflammation and Neuroprotection In Vitro and In Vivo.
Feng CW, Chen NF, Chan TF, Chen WF
Parkinson's disease 2020;2020:8814236
Parkinson's disease 2020;2020:8814236
Diazoxide Protects against Myocardial Ischemia/Reperfusion Injury by Moderating ERS via Regulation of the miR-10a/IRE1 Pathway.
Zhang L, Cai S, Cao S, Nie J, Zhou W, Zhang Y, Li K, Wang H, Yu S, Yu T
Oxidative medicine and cellular longevity 2020;2020:4957238
Oxidative medicine and cellular longevity 2020;2020:4957238
Salvianolic Acid B Improves Chronic Mild Stress-Induced Depressive Behaviors in Rats: Involvement of AMPK/SIRT1 Signaling Pathway.
Liao D, Chen Y, Guo Y, Wang C, Liu N, Gong Q, Fu Y, Fu Y, Cao L, Yao D, Jiang P
Journal of inflammation research 2020;13:195-206
Journal of inflammation research 2020;13:195-206
Chlorin A-mediated photodynamic therapy induced apoptosis in human cholangiocarcinoma cells via impaired autophagy flux.
He C, Xia J, Gao Y, Chen Z, Wan X
American journal of translational research 2020;12(9):5080-5094
American journal of translational research 2020;12(9):5080-5094
Role of Endoplasmic Reticulum Stress in Otitis Media.
Zhao H, Wang Y, Li B, Zheng T, Liu X, Hu BH, Che J, Zhao T, Chen J, Hatzoglou M, Zhang X, Fan Z, Zheng Q
Frontiers in genetics 2020;11:495
Frontiers in genetics 2020;11:495
ANKS4B Restricts Replication of Zika Virus by Downregulating the Autophagy.
Lin Q, Zhou S, Huang Y, Huo Z, Chen C, Luo X, He J, Liu C, Zhang P
Frontiers in microbiology 2020;11:1745
Frontiers in microbiology 2020;11:1745
Maimendong Decoction Improves Pulmonary Function in Rats With Idiopathic Pulmonary Fibrosis by Inhibiting Endoplasmic Reticulum Stress in AECIIs.
Shen M, Nan Y, Zhang L, Di L, He S, Li Y, Li Y
Frontiers in pharmacology 2020;11:1262
Frontiers in pharmacology 2020;11:1262
A paralog-specific role of COPI vesicles in the neuronal differentiation of mouse pluripotent cells.
Jain Goyal M, Zhao X, Bozhinova M, Andrade-López K, de Heus C, Schulze-Dramac S, Müller-McNicoll M, Klumperman J, Béthune J
Life science alliance 2020 Sep;3(9)
Life science alliance 2020 Sep;3(9)
Asiatic acid ameliorates acute hepatic injury by reducing endoplasmic reticulum stress and triggering hepatocyte autophagy.
Pang X, Qiao Q, Vonglorkham S, Feng Z, Pang L, Chen S, Wang D, Lao L, Lin X, Wei J
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Sep;129:110375
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Sep;129:110375
Reactive oxygen species mediate anlotinib-induced apoptosis via activation of endoplasmic reticulum stress in pancreatic cancer.
Yang L, Zhou X, Sun J, Lei Q, Wang Q, Pan D, Ding M, Ding Y
Cell death & disease 2020 Sep 17;11(9):766
Cell death & disease 2020 Sep 17;11(9):766
Liraglutide Up-regulation Thioredoxin Attenuated Müller Cells Apoptosis in High Glucose by Regulating Oxidative Stress and Endoplasmic Reticulum Stress.
Ren X, Sun L, Wei L, Liu J, Zhu J, Yu Q, Kong H, Kong L
Current eye research 2020 Oct;45(10):1283-1291
Current eye research 2020 Oct;45(10):1283-1291
ROS-mediated PERK-eIF2α-ATF4 pathway plays an important role in arsenite-induced L-02 cells apoptosis via regulating CHOP-DR5 signaling.
Liu C, Zhang A
Environmental toxicology 2020 Oct;35(10):1100-1113
Environmental toxicology 2020 Oct;35(10):1100-1113
Melatonin inhibits oxalate-induced endoplasmic reticulum stress and apoptosis in HK-2 cells by activating the AMPK pathway.
Song Q, He Z, Li B, Liu J, Liu L, Liao W, Xiong Y, Song C, Yang S, Liu Y
Cell cycle (Georgetown, Tex.) 2020 Oct;19(20):2600-2610
Cell cycle (Georgetown, Tex.) 2020 Oct;19(20):2600-2610
Neuroprotective mechanism of L-cysteine after subarachnoid hemorrhage.
Xiong Y, Xin DQ, Hu Q, Wang LX, Qiu J, Yuan HT, Chu XL, Liu DX, Li G, Wang Z
Neural regeneration research 2020 Oct;15(10):1920-1930
Neural regeneration research 2020 Oct;15(10):1920-1930
T-type calcium channel blockade induces apoptosis in C2C12 myotubes and skeletal muscle via endoplasmic reticulum stress activation.
Chen M, Li S, Hao M, Chen J, Zhao Z, Hong S, Min J, Tang J, Hu M, Hong L
FEBS open bio 2020 Oct;10(10):2122-2136
FEBS open bio 2020 Oct;10(10):2122-2136
IL-32 induces epithelial-mesenchymal transition by triggering endoplasmic reticulum stress in A549 cells.
Gong L, Liu G, Zhu H, Li C, Li P, Liu C, Tang H, Wu K, Wu J, Liu D, Tang X
BMC pulmonary medicine 2020 Oct 23;20(1):278
BMC pulmonary medicine 2020 Oct 23;20(1):278
Design, synthesis, and biological evaluation of 5-((8-methoxy-2-methylquinolin-4-yl)amino)-1H-indole-2-carbohydrazide derivatives as novel Nur77 modulators.
Li B, Yao J, Guo K, He F, Chen K, Lin Z, Liu S, Huang J, Wu Q, Fang M, Zeng J, Wu Z
European journal of medicinal chemistry 2020 Oct 15;204:112608
European journal of medicinal chemistry 2020 Oct 15;204:112608
Protective effects of pterostilbene against hepatic damage, redox imbalance, mitochondrial dysfunction, and endoplasmic reticulum stress in weanling piglets.
Zhang H, Chen Y, Li Y, Jia P, Ji S, Chen Y, Wang T
Journal of animal science 2020 Oct 1;98(10)
Journal of animal science 2020 Oct 1;98(10)
Aging is associated with increased TRB3, ER stress, and hepatic glucose production in the liver of rats.
Gaspar RC, Muñoz VR, Nakandakari SCBR, Vieira RFL, da Conceição LR, de Oliveira F, Crisol BM, da Silva ASR, Cintra DE, de Moura LP, Ropelle ER, Zaghloul I, Mekary RA, Pauli JR
Experimental gerontology 2020 Oct 1;139:111021
Experimental gerontology 2020 Oct 1;139:111021
Ubiquitin ligase CHIP regulates OTUD3 stability and suppresses tumour metastasis in lung cancer.
Zhang P, Li C, Li H, Yuan L, Dai H, Peng Z, Deng Z, Chang Z, Cui CP, Zhang L
Cell death and differentiation 2020 Nov;27(11):3177-3195
Cell death and differentiation 2020 Nov;27(11):3177-3195
TRPV4 contributes to ER stress: Relation to apoptosis in the MPP+-induced cell model of Parkinson's disease.
Liu N, Liu J, Wen X, Bai L, Shao R, Bai J
Life sciences 2020 Nov 15;261:118461
Life sciences 2020 Nov 15;261:118461
Acupuncture protects against cerebral ischemia-reperfusion injury via suppressing endoplasmic reticulum stress-mediated autophagy and apoptosis.
Sun X, Liu H, Sun Z, Zhang B, Wang X, Liu T, Pan T, Gao Y, Jiang X, Li H
Molecular medicine (Cambridge, Mass.) 2020 Nov 10;26(1):105
Molecular medicine (Cambridge, Mass.) 2020 Nov 10;26(1):105
Cleavage of cyclic AMP-responsive element-binding protein H aggravates myocardial hypoxia reperfusion injury in a hepatocyte-myocardial cell co-culture system.
Jin Z, Chen Y, Weng X, Huang A, Lin S, Li H
The Journal of international medical research 2020 May;48(5):300060520904835
The Journal of international medical research 2020 May;48(5):300060520904835
Exogenous spermine attenuates rat diabetic cardiomyopathy via suppressing ROS-p53 mediated downregulation of calcium-sensitive receptor.
Wang Y, Chen J, Li S, Zhang X, Guo Z, Hu J, Shao X, Song N, Zhao Y, Li H, Yang G, Xu C, Wei C
Redox biology 2020 May;32:101514
Redox biology 2020 May;32:101514
Pyruvate alleviates high glucose-induced endoplasmic reticulum stress and apoptosis in HK-2 cells.
Zhang XM, Wang YZ, Tong JD, Ning XC, Zhou FQ, Yang XH, Jin HM
FEBS open bio 2020 May;10(5):827-834
FEBS open bio 2020 May;10(5):827-834
Sigma-1 receptor activity in primary sensory neurons is a critical driver of neuropathic pain.
Shin SM, Wang F, Qiu C, Itson-Zoske B, Hogan QH, Yu H
Gene therapy 2020 May 18;
Gene therapy 2020 May 18;
miR-384-5p promotes spinal cord injury recovery in rats through suppressing of autophagy and endoplasmic reticulum stress.
Zhou Z, Hu B, Lyu Q, Xie T, Wang J, Cai Q
Neuroscience letters 2020 May 14;727:134937
Neuroscience letters 2020 May 14;727:134937
Knockout of DNase1l1l abrogates lens denucleation process and causes cataract in zebrafish.
Zhang J, Cui WW, Du C, Huang Y, Pi X, Guo W, Wang J, Huang W, Chen D, Li J, Li H, Zhang J, Ma Y, Mu H, Zhang S, Liu M, Cui X, Hu Y
Biochimica et biophysica acta. Molecular basis of disease 2020 May 1;1866(5):165724
Biochimica et biophysica acta. Molecular basis of disease 2020 May 1;1866(5):165724
Xanthatin induces glioma cell apoptosis and inhibits tumor growth via activating endoplasmic reticulum stress-dependent CHOP pathway.
Ma YY, Di ZM, Cao Q, Xu WS, Bi SX, Yu JS, Shen YJ, Yu YQ, Shen YX, Feng LJ
Acta pharmacologica Sinica 2020 Mar;41(3):404-414
Acta pharmacologica Sinica 2020 Mar;41(3):404-414
Blockade of HSP70 by VER-155008 synergistically enhances bortezomib-induced cytotoxicity in multiple myeloma.
Huang L, Wang Y, Bai J, Yang Y, Wang F, Feng Y, Zhang R, Li F, Zhang P, Lv N, Lei L, Hu J, He A
Cell stress & chaperones 2020 Mar;25(2):357-367
Cell stress & chaperones 2020 Mar;25(2):357-367
Intrabody against prolyl hydroxylase 2 ameliorates acetaminophen-induced acute liver injury in mice via concomitant promotion of angiogenesis and redox homeostasis.
Zhao L, Zhao J, Gao R, Tian Y, Zhang Y, Tang W, Jiang Y, Li C, Wang M, Yang F, Li G
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Mar;123:109783
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Mar;123:109783
A novel splice site indel alteration in the EIF2AK3 gene is responsible for the first cases of Wolcott-Rallison syndrome in Hungary.
Sümegi A, Hendrik Z, Gáll T, Felszeghy E, Szakszon K, Antal-Szalmás P, Beke L, Papp Á, Méhes G, Balla J, Balla G
BMC medical genetics 2020 Mar 27;21(1):61
BMC medical genetics 2020 Mar 27;21(1):61
A light-triggered self-reinforced nanoagent for targeted chemo-photodynamic therapy of breast cancer bone metastases via ER stress and mitochondria mediated apoptotic pathways.
Huang Y, Xiao Z, Guan Z, Shen Y, Jiang Y, Xu X, Huang Z, Zhao C
Journal of controlled release : official journal of the Controlled Release Society 2020 Mar 10;319:119-134
Journal of controlled release : official journal of the Controlled Release Society 2020 Mar 10;319:119-134
Endoplasmic Reticulum Stress Signalling Induces Casein Kinase 1-Dependent Formation of Cytosolic TDP-43 Inclusions in Motor Neuron-Like Cells.
Hicks DA, Cross LL, Williamson R, Rattray M
Neurochemical research 2020 Jun;45(6):1354-1364
Neurochemical research 2020 Jun;45(6):1354-1364
Iodine‑125 seed radiation induces ROS‑mediated apoptosis, autophagy and paraptosis in human esophageal squamous cell carcinoma cells.
Wang C, Li TK, Zeng CH, Fan R, Wang Y, Zhu GY, Guo JH
Oncology reports 2020 Jun;43(6):2028-2044
Oncology reports 2020 Jun;43(6):2028-2044
Sulforaphane attenuates apoptosis of hippocampal neurons induced by high glucose via regulating endoplasmic reticulum.
Tang L, Ren X, Han Y, Chen L, Meng X, Zhang C, Chu H, Kong L, Ma H
Neurochemistry international 2020 Jun;136:104728
Neurochemistry international 2020 Jun;136:104728
Ubiquitin C-terminal hydrolase L1 (UCHL1) regulates post-myocardial infarction cardiac fibrosis through glucose-regulated protein of 78 kDa (GRP78).
Lei Q, Yi T, Li H, Yan Z, Lv Z, Li G, Wang Y
Scientific reports 2020 Jun 30;10(1):10604
Scientific reports 2020 Jun 30;10(1):10604
UBE2T promotes glioblastoma invasion and migration via stabilizing GRP78 and regulating EMT.
Huang P, Guo Y, Zhao Z, Ning W, Wang H, Gu C, Zhang M, Qu Y, Zhang H, Song Y
Aging 2020 Jun 3;12(11):10275-10289
Aging 2020 Jun 3;12(11):10275-10289
Excretory/secretory products of Angiostrongylus cantonensis fifth-stage larvae induce endoplasmic reticulum stress via the Sonic hedgehog pathway in mouse astrocytes.
Chen KY, Chen YJ, Cheng CJ, Jhan KY, Wang LC
Parasites & vectors 2020 Jun 18;13(1):317
Parasites & vectors 2020 Jun 18;13(1):317
Perinatal low-dose PBDE-47 exposure hampered thyroglobulin turnover and induced thyroid cell apoptosis by triggering ER stress and lysosomal destabilization contributing to thyroid toxicity in adult female rats.
Li P, Gao H, Dong L, Liu L, Zhou G, Luo C, Tian Z, Xia T, Wang A, Zhang S
Journal of hazardous materials 2020 Jun 15;392:122265
Journal of hazardous materials 2020 Jun 15;392:122265
Polychlorinated Biphenyl Quinone Promotes Atherosclerosis through Lipid Accumulation and Endoplasmic Reticulum Stress via CD36.
Yang B, Qin Q, Xu L, Lv X, Liu Z, Song E, Song Y
Chemical research in toxicology 2020 Jun 15;33(6):1497-1507
Chemical research in toxicology 2020 Jun 15;33(6):1497-1507
Non-Esterified Fatty Acid-Induced Reactive Oxygen Species Mediated Granulosa Cells Apoptosis Is Regulated by Nrf2/p53 Signaling Pathway.
Wang Y, Li C, Li J, Wang G, Li L
Antioxidants (Basel, Switzerland) 2020 Jun 14;9(6)
Antioxidants (Basel, Switzerland) 2020 Jun 14;9(6)
SHQ1 is an ER stress response gene that facilitates chemotherapeutics-induced apoptosis via sensitizing ER-stress response.
Liu H, Xie S, Fang F, Kalvakolanu DV, Xiao W
Cell death & disease 2020 Jun 10;11(6):445
Cell death & disease 2020 Jun 10;11(6):445
Circulating Exosomes From Lipopolysaccharide-Induced Ards Mice Trigger Endoplasmic Reticulum Stress in Lung Tissue.
Tang X, Yu Q, Wen X, Qi D, Peng J, He J, Deng W, Zhu T, Zhao Y, Wang D
Shock (Augusta, Ga.) 2020 Jul;54(1):110-118
Shock (Augusta, Ga.) 2020 Jul;54(1):110-118
Extracellular Vesicles Isolated from Human Induced Pluripotent Stem Cell-Derived Neurons Contain a Transcriptional Network.
Hicks DA, Jones AC, Corbett NJ, Fisher K, Pickering-Brown SM, Ashe MP, Hooper NM
Neurochemical research 2020 Jul;45(7):1711-1728
Neurochemical research 2020 Jul;45(7):1711-1728
Endosulfan induces endothelial inflammation and dysfunction via IRE1α/NF-κB signaling pathway.
Sun S, Ji Z, Fu J, Wang XF, Zhang LS
Environmental science and pollution research international 2020 Jul;27(21):26163-26171
Environmental science and pollution research international 2020 Jul;27(21):26163-26171
78 kDa Glucose-Regulated Protein Attenuates Protein Aggregation and Monocyte Adhesion Induced by Angiotensin II in Vascular Cells.
Cicalese S, Okuno K, Elliott KJ, Kawai T, Scalia R, Rizzo V, Eguchi S
International journal of molecular sciences 2020 Jul 15;21(14)
International journal of molecular sciences 2020 Jul 15;21(14)
Liraglutide protects pancreatic β cells from endoplasmic reticulum stress by upregulating MANF to promote autophagy turnover.
Fu J, Nchambi KM, Wu H, Luo X, An X, Liu D
Life sciences 2020 Jul 1;252:117648
Life sciences 2020 Jul 1;252:117648
Withaferin A triggers G2/M arrest and intrinsic apoptosis in glioblastoma cells via ATF4-ATF3-CHOP axis.
Tang Q, Ren L, Liu J, Li W, Zheng X, Wang J, Du G
Cell proliferation 2020 Jan;53(1):e12706
Cell proliferation 2020 Jan;53(1):e12706
Selenium Attenuates Chronic Heat Stress-Induced Apoptosis via the Inhibition of Endoplasmic Reticulum Stress in Mouse Granulosa Cells.
Xiong Y, Yin Q, Jin E, Chen H, He S
Molecules (Basel, Switzerland) 2020 Jan 28;25(3)
Molecules (Basel, Switzerland) 2020 Jan 28;25(3)
MCP-1 mediates ischemia-reperfusion-induced cardiomyocyte apoptosis via MCPIP1 and CaSR.
Zhang W, Zhu T, Chen L, Luo W, Chao J
American journal of physiology. Heart and circulatory physiology 2020 Jan 1;318(1):H59-H71
American journal of physiology. Heart and circulatory physiology 2020 Jan 1;318(1):H59-H71
Hydrogen sulfide regulates muscle RING finger-1 protein S-sulfhydration at Cys(44) to prevent cardiac structural damage in diabetic cardiomyopathy.
Sun X, Zhao D, Lu F, Peng S, Yu M, Liu N, Sun Y, Du H, Wang B, Chen J, Dong S, Lu F, Zhang W
British journal of pharmacology 2020 Feb;177(4):836-856
British journal of pharmacology 2020 Feb;177(4):836-856
Protective effect of Liraglutide on diabetic retinal neurodegeneration via inhibiting oxidative stress and endoplasmic reticulum stress.
Liu J, Wei L, Wang Z, Song S, Lin Z, Zhu J, Ren X, Kong L
Neurochemistry international 2020 Feb;133:104624
Neurochemistry international 2020 Feb;133:104624
Clinicopathological significance of endoplasmic reticulum stress proteins in ovarian carcinoma.
Samanta S, Tamura S, Dubeau L, Mhawech-Fauceglia P, Miyagi Y, Kato H, Lieberman R, Buckanovich RJ, Lin YG, Neamati N
Scientific reports 2020 Feb 7;10(1):2160
Scientific reports 2020 Feb 7;10(1):2160
Oxidative Stress and Endoplasmic Reticulum Stress Are Involved in the Protective Effect of Alpha Lipoic Acid Against Heat Damage in Chicken Testes.
Xiong Y, Yin Q, Li J, He S
Animals : an open access journal from MDPI 2020 Feb 27;10(3)
Animals : an open access journal from MDPI 2020 Feb 27;10(3)
Protection of retinal function and morphology in MNU-induced retinitis pigmentosa rats by ALDH2: an in-vivo study.
Yan W, Long P, Wei D, Yan W, Zheng X, Chen G, Wang J, Zhang Z, Chen T, Chen M
BMC ophthalmology 2020 Feb 18;20(1):55
BMC ophthalmology 2020 Feb 18;20(1):55
Hepatic DNAJB9 Drives Anabolic Biasing to Reduce Steatosis and Obesity.
Sun F, Liao Y, Qu X, Xiao X, Hou S, Chen Z, Huang H, Li P, Fu S
Cell reports 2020 Feb 11;30(6):1835-1847.e9
Cell reports 2020 Feb 11;30(6):1835-1847.e9
Fengbaisan suppresses endoplasmic reticulum stress by up-regulating SIRT1 expression to protect rats with chronic obstructive pulmonary diseases.
Wang Y, Su NX, Pan SG, Ge XP, Dai XP
Pharmaceutical biology 2020 Dec;58(1):878-885
Pharmaceutical biology 2020 Dec;58(1):878-885
NLRP3 inflammasome and endoplasmic reticulum stress in the epileptogenic zone in temporal lobe epilepsy: molecular insights into their interdependence.
Yue J, Wei YJ, Yang XL, Liu SY, Yang H, Zhang CQ
Neuropathology and applied neurobiology 2020 Dec;46(7):770-785
Neuropathology and applied neurobiology 2020 Dec;46(7):770-785
Zinc application alleviates the adverse renal effects of arsenic stress in a protein quality control way in common carp.
Wang Y, Zhao H, Nie X, Guo M, Jiang G, Xing M
Environmental research 2020 Dec;191:110063
Environmental research 2020 Dec;191:110063
Exogenous hydrogen sulfide inhibits apoptosis by regulating endoplasmic reticulum stress-autophagy axis and improves myocardial reconstruction after acute myocardial infarction.
Li Y, Liu M, Yi J, Song X, Zheng X, Liu D, Wang S, Chu C, Yang J
Acta biochimica et biophysica Sinica 2020 Dec 29;52(12):1325-1336
Acta biochimica et biophysica Sinica 2020 Dec 29;52(12):1325-1336
ALDH2 protects naturally aged mouse retina via inhibiting oxidative stress-related apoptosis and enhancing unfolded protein response in endoplasmic reticulum.
Long P, He M, Yan W, Chen W, Wei D, Wang S, Zhang Z, Ge W, Chen T
Aging 2020 Dec 19;13(2):2750-2767
Aging 2020 Dec 19;13(2):2750-2767
Cell cycle exit during bortezomib-induced osteogenic differentiation of mesenchymal stem cells was mediated by Xbp1s-upregulated p21Cip1 and p27Kip1.
Zhang D, Fan R, Lei L, Lei L, Wang Y, Lv N, Chen P, Williamson RA, Wang B, Hu J
Journal of cellular and molecular medicine 2020 Aug;24(16):9428-9438
Journal of cellular and molecular medicine 2020 Aug;24(16):9428-9438
Hydrogen sulphide ameliorating skeletal muscle atrophy in db/db mice via Muscle RING finger 1 S-sulfhydration.
Lu F, Lu B, Zhang L, Wen J, Wang M, Zhang S, Li Q, Shu F, Sun Y, Liu N, Peng S, Zhao Y, Dong S, Zhao D, Lu F, Zhang W
Journal of cellular and molecular medicine 2020 Aug;24(16):9362-9377
Journal of cellular and molecular medicine 2020 Aug;24(16):9362-9377
Proteomic Analysis Reveals Proteins and Pathways Associated with Lactation in Bovine Mammary Epithelial Cell-Derived Exosomes.
Zhang M, Ma Z, Li R, Guo S, Qiu Y, Gao X
Journal of proteome research 2020 Aug 7;19(8):3211-3219
Journal of proteome research 2020 Aug 7;19(8):3211-3219
FGF21 mitigates atherosclerosis via inhibition of NLRP3 inflammasome-mediated vascular endothelial cells pyroptosis.
Zeng Z, Zheng Q, Chen J, Tan X, Li Q, Ding L, Zhang R, Lin X
Experimental cell research 2020 Aug 15;393(2):112108
Experimental cell research 2020 Aug 15;393(2):112108
LncRNA GUARDIN suppresses cellular senescence through a LRP130-PGC1α-FOXO4-p21-dependent signaling axis.
Sun X, Thorne RF, Zhang XD, He M, Li J, Feng S, Liu X, Wu M
EMBO reports 2020 Apr 3;21(4):e48796
EMBO reports 2020 Apr 3;21(4):e48796
CACNA1H downregulation induces skeletal muscle atrophy involving endoplasmic reticulum stress activation and autophagy flux blockade.
Li S, Hao M, Li B, Chen M, Chen J, Tang J, Hong S, Min J, Hu M, Hong L
Cell death & disease 2020 Apr 24;11(4):279
Cell death & disease 2020 Apr 24;11(4):279
Exosomes from mesenchymal stem cells modulate endoplasmic reticulum stress to protect against nucleus pulposus cell death and ameliorate intervertebral disc degeneration in vivo.
Liao Z, Luo R, Li G, Song Y, Zhan S, Zhao K, Hua W, Zhang Y, Wu X, Yang C
Theranostics 2019;9(14):4084-4100
Theranostics 2019;9(14):4084-4100
GRP78 regulates milk biosynthesis and the proliferation of bovinemammaryepithelial cells through the mTOR signaling pathway.
Liu Y, Wang X, Zhen Z, Yu Y, Qiu Y, Xiang W
Cellular & molecular biology letters 2019;24:57
Cellular & molecular biology letters 2019;24:57
Unfolded Protein Response Pathways Correlatively Modulate Endoplasmic Reticulum Stress Responses in Rat Retinal Müller Cells.
Wu S, Zhu X, Guo B, Zheng T, Ren J, Zeng W, Chen X, Ke M
Journal of ophthalmology 2019;2019:9028483
Journal of ophthalmology 2019;2019:9028483
Betulinic Acid Suppresses Breast Cancer Metastasis by Targeting GRP78-Mediated Glycolysis and ER Stress Apoptotic Pathway.
Zheng Y, Liu P, Wang N, Wang S, Yang B, Li M, Chen J, Situ H, Xie M, Lin Y, Wang Z
Oxidative medicine and cellular longevity 2019;2019:8781690
Oxidative medicine and cellular longevity 2019;2019:8781690
UFL1 Alleviates Lipopolysaccharide-Induced Cell Damage and Inflammation via Regulation of the TLR4/NF-κB Pathway in Bovine Mammary Epithelial Cells.
Li C, Li L, Chen K, Wang Y, Yang F, Wang G
Oxidative medicine and cellular longevity 2019;2019:6505373
Oxidative medicine and cellular longevity 2019;2019:6505373
ZYZ-803 Mitigates Endoplasmic Reticulum Stress-Related Necroptosis after Acute Myocardial Infarction through Downregulating the RIP3-CaMKII Signaling Pathway.
Chang L, Wang Z, Ma F, Tran B, Zhong R, Xiong Y, Dai T, Wu J, Xin X, Guo W, Xie Y, Mao Y, Zhu YZ
Oxidative medicine and cellular longevity 2019;2019:6173685
Oxidative medicine and cellular longevity 2019;2019:6173685
Alpha-mangostin induces endoplasmic reticulum stress and autophagy which count against fatty acid synthase inhibition mediated apoptosis in human breast cancer cells.
Huang W, Liang Y, Ma X
Cancer cell international 2019;19:151
Cancer cell international 2019;19:151
The IRE1α-XBP1 pathway function in hypoxia-induced pulmonary vascular remodeling, is upregulated by quercetin, inhibits apoptosis and partially reverses the effect of quercetin in PASMCs.
Cao X, He Y, Li X, Xu Y, Liu X
American journal of translational research 2019;11(2):641-654
American journal of translational research 2019;11(2):641-654
Antimetastatic Effect of Fucoidan-Sargassum against Liver Cancer Cell Invadopodia Formation via Targeting Integrin αVβ3 and Mediating αVβ3/Src/E2F1 Signaling.
Pan TJ, Li LX, Zhang JW, Yang ZS, Shi DM, Yang YK, Wu WZ
Journal of Cancer 2019;10(20):4777-4792
Journal of Cancer 2019;10(20):4777-4792
Abnormal Glucose Metabolism and Insulin Resistance Are Induced via the IRE1α/XBP-1 Pathway in Subclinical Hypothyroidism.
Xu C, Zhou L, Wu K, Li Y, Xu J, Jiang D, Gao L
Frontiers in endocrinology 2019;10:303
Frontiers in endocrinology 2019;10:303
Vildagliptin Reduces Stenosis of Injured Carotid Artery in Diabetic Mouse Through Inhibiting Vascular Smooth Muscle Cell Proliferation via ER Stress/NF-κB Pathway.
Ji Y, Ge Y, Xu X, Ye S, Fan Y, Zhang J, Mei L, Zhang X, Ying L, Yang T, Li C
Frontiers in pharmacology 2019;10:142
Frontiers in pharmacology 2019;10:142
Correction to: Protective effects of dioscin against alcohol‑induced liver injury.
Xu T, Zheng L, Xu L, Yin L, Qi Y, Xu Y, Han X, Peng J
Archives of toxicology 2019 Sep;93(9):2713
Archives of toxicology 2019 Sep;93(9):2713
Regulatory role of Golgi brefeldin A resistance factor-1 in amyloid precursor protein trafficking, cleavage and Aβ formation.
Liu K, Liu Y, Xu Y, Nandakumar KS, Shen X, Lin J, Li C, He C, Zhou C
Journal of cellular biochemistry 2019 Sep;120(9):15604-15615
Journal of cellular biochemistry 2019 Sep;120(9):15604-15615
Mechanisms of IFNalpha-1a-Induced Apoptosis in a Laryngeal Cancer Cell Line.
Xin XL, Zhang R, Yuan XM, Liu L
Medical science monitor : international medical journal of experimental and clinical research 2019 Sep 22;25:7100-7114
Medical science monitor : international medical journal of experimental and clinical research 2019 Sep 22;25:7100-7114
BDE-209 induces autophagy and apoptosis via IRE1α/Akt/mTOR signaling pathway in human umbilical vein endothelial cells.
Hou Y, Fu J, Sun S, Jin Y, Wang X, Zhang L
Environmental pollution (Barking, Essex : 1987) 2019 Oct;253:429-438
Environmental pollution (Barking, Essex : 1987) 2019 Oct;253:429-438
Resveratrol reduces brain injury after subarachnoid hemorrhage by inhibiting oxidative stress and endoplasmic reticulum stress.
Xie YK, Zhou X, Yuan HT, Qiu J, Xin DQ, Chu XL, Wang DC, Wang Z
Neural regeneration research 2019 Oct;14(10):1734-1742
Neural regeneration research 2019 Oct;14(10):1734-1742
Suhuang antitussive capsule inhibits NLRP3 inflammasome activation and ameliorates pulmonary dysfunction via suppression of endoplasmic reticulum stress in cough variant asthma.
Qin W, Wu X, Jia Y, Tong X, Guo C, Chen D, Wang Z, Tan N
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Oct;118:109188
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Oct;118:109188
Niban protein regulates apoptosis in HK-2 cells via caspase-dependent pathway.
Tang S, Wang J, Liu J, Huang Y, Zhou Y, Yang S, Zhang W, Yang M, Zhang H
Renal failure 2019 Nov;41(1):455-466
Renal failure 2019 Nov;41(1):455-466
Lopinavir-Ritonavir Combination Induces Endoplasmic Reticulum Stress and Kills Urological Cancer Cells.
Okubo K, Isono M, Asano T, Sato A
Anticancer research 2019 Nov;39(11):5891-5901
Anticancer research 2019 Nov;39(11):5891-5901
Impaired calcium homeostasis via advanced glycation end products promotes apoptosis through endoplasmic reticulum stress in human nucleus pulposus cells and exacerbates intervertebral disc degeneration in rats.
Luo R, Song Y, Liao Z, Yin H, Zhan S, Wang K, Li S, Li G, Ma L, Lu S, Zhang Y, Yang C
The FEBS journal 2019 Nov;286(21):4356-4373
The FEBS journal 2019 Nov;286(21):4356-4373
Sevoflurane modulates AQPs (1,5) expression and endoplasmic reticulum stress in mice lung with allergic airway inflammation.
Lv CM, Wu HM, Wu L, Xu GH, Yang ZL, Shen QY
Bioscience reports 2019 Nov 29;39(11)
Bioscience reports 2019 Nov 29;39(11)
Inhibiting lysine 353 oxidation of GRP78 by a hypochlorous probe targeting endoplasmic reticulum promotes autophagy in cancer cells.
Ning J, Lin Z, Zhao X, Zhao B, Miao J
Cell death & disease 2019 Nov 12;10(11):858
Cell death & disease 2019 Nov 12;10(11):858
ER stress activation impairs the expression of circadian clock and clock-controlled genes in NIH3T3 cells via an ATF4-dependent mechanism.
Gao L, Chen H, Li C, Xiao Y, Yang D, Zhang M, Zhou D, Liu W, Wang A, Jin Y
Cellular signalling 2019 May;57:89-101
Cellular signalling 2019 May;57:89-101
Quantitative interaction proteomics reveals differences in the interactomes of amyloid precursor protein isoforms.
Andrew RJ, Fisher K, Heesom KJ, Kellett KAB, Hooper NM
Journal of neurochemistry 2019 May;149(3):399-412
Journal of neurochemistry 2019 May;149(3):399-412
Flaccidoxide-13-Acetate-Induced Apoptosis in Human Bladder Cancer Cells is through Activation of p38/JNK, Mitochondrial Dysfunction, and Endoplasmic Reticulum Stress Regulated Pathway.
Wu YJ, Su TR, Dai GF, Su JH, Liu CI
Marine drugs 2019 May 13;17(5)
Marine drugs 2019 May 13;17(5)
ERp29 counteracts the suppression of malignancy mediated by endoplasmic reticulum stress and promotes the metastasis of colorectal cancer.
Guo L, Ma L, Liu C, Lei Y, Tang N, Huang Y, Huang G, Li D, Wang Q, Liu G, Tang M, Jing Z, Deng Y
Oncology reports 2019 Mar;41(3):1603-1615
Oncology reports 2019 Mar;41(3):1603-1615
High-fat diet induces aberrant hepatic lipid secretion in blunt snout bream by activating endoplasmic reticulum stress-associated IRE1/XBP1 pathway.
Cao XF, Dai YJ, Liu MY, Yuan XY, Wang CC, Huang YY, Liu WB, Jiang GZ
Biochimica et biophysica acta. Molecular and cell biology of lipids 2019 Mar;1864(3):213-223
Biochimica et biophysica acta. Molecular and cell biology of lipids 2019 Mar;1864(3):213-223
Pharmacological preconditioning with the cellular stress inducer thapsigargin protects against experimental sepsis.
Wei Y, Meng M, Tian Z, Xie F, Yin Q, Dai C, Wang J, Zhang Q, Liu Y, Liu C, Yan F, Jiang F, Guo X
Pharmacological research 2019 Mar;141:114-122
Pharmacological research 2019 Mar;141:114-122
Low-concentration HCP1 inhibits apoptosis in vascular endothelial cells.
Wei Q, Zhang J, Su L, Zhao X, Zhao B, Miao J, Lin Z
Biochemical and biophysical research communications 2019 Mar 26;511(1):92-98
Biochemical and biophysical research communications 2019 Mar 26;511(1):92-98
Quantitative proteomic analysis of deer antler stem cells as a model of mammalian organ regeneration.
Dong Z, Coates D, Liu Q, Sun H, Li C
Journal of proteomics 2019 Mar 20;195:98-113
Journal of proteomics 2019 Mar 20;195:98-113
A Legionella pneumophila Kinase Phosphorylates the Hsp70 Chaperone Family to Inhibit Eukaryotic Protein Synthesis.
Moss SM, Taylor IR, Ruggero D, Gestwicki JE, Shokat KM, Mukherjee S
Cell host & microbe 2019 Mar 13;25(3):454-462.e6
Cell host & microbe 2019 Mar 13;25(3):454-462.e6
Cyclophilin B control of lysine post-translational modifications of skin type I collagen.
Terajima M, Taga Y, Cabral WA, Liu Y, Nagasawa M, Sumida N, Kayashima Y, Chandrasekaran P, Han L, Maeda N, Perdivara I, Hattori S, Marini JC, Yamauchi M
PLoS genetics 2019 Jun;15(6):e1008196
PLoS genetics 2019 Jun;15(6):e1008196
Exosomes from Microglia Attenuate Photoreceptor Injury and Neovascularization in an Animal Model of Retinopathy of Prematurity.
Xu W, Wu Y, Hu Z, Sun L, Dou G, Zhang Z, Wang H, Guo C, Wang Y
Molecular therapy. Nucleic acids 2019 Jun 7;16:778-790
Molecular therapy. Nucleic acids 2019 Jun 7;16:778-790
APS could potentially activate hepatic insulin signaling in HFD-induced IR mice.
Sun J, Liu Y, Yu J, Wu J, Gao W, Ran L, Jiang R, Guo M, Han D, Liu B, Wang N, Li Y, Huang H, Zeng L, Gao Y, Li X, Wu Y
Journal of molecular endocrinology 2019 Jul;63(1):77-91
Journal of molecular endocrinology 2019 Jul;63(1):77-91
Metformin induces TPC-1 cell apoptosis through endoplasmic reticulum stress-associated pathways in vitro and in vivo.
Ye J, Qi L, Chen K, Li R, Song S, Zhou C, Zhai W
International journal of oncology 2019 Jul;55(1):331-339
International journal of oncology 2019 Jul;55(1):331-339
Knockdown of TM9SF4 boosts ER stress to trigger cell death of chemoresistant breast cancer cells.
Zhu Y, Xie M, Meng Z, Leung LK, Chan FL, Hu X, Chi K, Liu C, Yao X
Oncogene 2019 Jul;38(29):5778-5791
Oncogene 2019 Jul;38(29):5778-5791
Ranolazine prevents pressure overload-induced cardiac hypertrophy and heart failure by restoring aberrant Na+ and Ca2+ handling.
Nie J, Duan Q, He M, Li X, Wang B, Zhou C, Wu L, Wen Z, Chen C, Wang DW, Alsina KM, Wehrens XHT, Wang DW, Ni L
Journal of cellular physiology 2019 Jul;234(7):11587-11601
Journal of cellular physiology 2019 Jul;234(7):11587-11601
Paneth cell ablation increases the small intestinal injury during acute necrotizing pancreatitis in rats.
Liu L, Guo Y, Zheng J, Lu Y, Shen Y, Huang C, Zeng Y, Wang X
Molecular medicine reports 2019 Jul;20(1):473-484
Molecular medicine reports 2019 Jul;20(1):473-484
The deubiquitylase OTUD3 stabilizes GRP78 and promotes lung tumorigenesis.
Du T, Li H, Fan Y, Yuan L, Guo X, Zhu Q, Yao Y, Li X, Liu C, Yu X, Liu Z, Cui CP, Han C, Zhang L
Nature communications 2019 Jul 2;10(1):2914
Nature communications 2019 Jul 2;10(1):2914
Induction of Endoplasmic Reticulum Stress by Cadmium and Its Regulation on Nrf2 Signaling Pathway in Kidneys of Rats.
Chen ZJ, Chen JX, Wu LK, Li BY, Tian YF, Xian M, Huang ZP, Yu RA
Biomedical and environmental sciences : BES 2019 Jan;32(1):1-10
Biomedical and environmental sciences : BES 2019 Jan;32(1):1-10
Autophagy activation alleviates nonylphenol-induced apoptosis in cultured cortical neurons.
Li S, Jiang Z, Chai W, Xu Y, Wang Y
Neurochemistry international 2019 Jan;122:73-84
Neurochemistry international 2019 Jan;122:73-84
Pterostilbene exerts a protective effect via regulating tunicamycin-induced endoplasmic reticulum stress in mouse preimplantation embryos.
Ullah O, Li Z, Ali I, Xu L, Liu H, Jin HZ, Fang YY, Jin QG, Fang N
In vitro cellular & developmental biology. Animal 2019 Feb;55(2):82-93
In vitro cellular & developmental biology. Animal 2019 Feb;55(2):82-93
MiR-451a suppressing BAP31 can inhibit proliferation and increase apoptosis through inducing ER stress in colorectal cancer.
Xu K, Han B, Bai Y, Ma XY, Ji ZN, Xiong Y, Miao SK, Zhang YY, Zhou LM
Cell death & disease 2019 Feb 15;10(3):152
Cell death & disease 2019 Feb 15;10(3):152
Mesencephalic astrocyte-derived neurotrophic factor (MANF) protects against Aβ toxicity via attenuating Aβ-induced endoplasmic reticulum stress.
Xu S, Di Z, He Y, Wang R, Ma Y, Sun R, Li J, Wang T, Shen Y, Fang S, Feng L, Shen Y
Journal of neuroinflammation 2019 Feb 13;16(1):35
Journal of neuroinflammation 2019 Feb 13;16(1):35
Chronic intermittent hypoxia accelerates liver fibrosis in rats with combined hypoxia and nonalcoholic steatohepatitis via angiogenesis rather than endoplasmic reticulum stress.
Wu W, Li W, Wei J, Wang C, Yao Y, Zhu W, He W, Zhou W, Liu J
Acta biochimica et biophysica Sinica 2019 Feb 1;51(2):159-167
Acta biochimica et biophysica Sinica 2019 Feb 1;51(2):159-167
Induction of the unfolded protein response (UPR) during pseudorabies virus infection.
Yang S, Zhu J, Zhou X, Wang H, Li X, Zhao A
Veterinary microbiology 2019 Dec;239:108485
Veterinary microbiology 2019 Dec;239:108485
Inhibition of CACNA1H attenuates doxorubicin-induced acute cardiotoxicity by affecting endoplasmic reticulum stress.
Hu J, Wu Q, Wang Z, Hong J, Chen R, Li B, Hu Z, Hu X, Zhang M
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Dec;120:109475
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Dec;120:109475
Signaling from mTOR to eIF2α mediates cell migration in response to the chemotherapeutic doxorubicin.
Harvey RF, Pöyry TAA, Stoneley M, Willis AE
Science signaling 2019 Dec 17;12(612)
Science signaling 2019 Dec 17;12(612)
Human placenta-derived mesenchymal stem cells inhibit apoptosis of granulosa cells induced by IRE1α pathway in autoimmune POF mice.
Li H, Zhao W, Wang L, Luo Q, Yin N, Lu X, Hou Y, Cui J, Zhang H
Cell biology international 2019 Aug;43(8):899-909
Cell biology international 2019 Aug;43(8):899-909
Bone marrow mesenchymal stem cells could reduce the toxic effects of hexavalent chromium on the liver by decreasing endoplasmic reticulum stress-mediated apoptosis via SIRT1/HIF-1α signaling pathway in rats.
Zhao Y, Yan J, Li AP, Zhang ZL, Li ZR, Guo KJ, Zhao KC, Ruan Q, Guo L
Toxicology letters 2019 Aug;310:31-38
Toxicology letters 2019 Aug;310:31-38
Proteomic analysis of retinal pigment epithelium cells after exposure to UVA radiation.
Chen JL, Hung CT, Keller JJ, Lin HC, Wu YJ
BMC ophthalmology 2019 Aug 2;19(1):168
BMC ophthalmology 2019 Aug 2;19(1):168
The IRE1 signaling pathway is involved in the protective effect of low-dose LPS on myocardial ischemia-reperfusion injury.
Wu T, Jiang N, Ji Z, Shi G
Life sciences 2019 Aug 15;231:116569
Life sciences 2019 Aug 15;231:116569
Prion Protein Protects Cancer Cells against Endoplasmic Reticulum Stress Induced Apoptosis.
Gao Z, Peng M, Chen L, Yang X, Li H, Shi R, Wu G, Cai L, Song Q, Li C
Virologica Sinica 2019 Apr;34(2):222-234
Virologica Sinica 2019 Apr;34(2):222-234
Porcine Circovirus Type 2 Induces ORF3-Independent Mitochondrial Apoptosis via PERK Activation and Elevation of Cytosolic Calcium.
Zhang Y, Sun R, Geng S, Shan Y, Li X, Fang W
Journal of virology 2019 Apr 1;93(7)
Journal of virology 2019 Apr 1;93(7)
Differentially expressed genes of HepG2 cells treated with gecko polypeptide mixture.
Duan YM, Jin Y, Guo ML, Duan LX, Wang JG
Journal of Cancer 2018;9(15):2723-2733
Journal of Cancer 2018;9(15):2723-2733
Heme Induces Endoplasmic Reticulum Stress (HIER Stress) in Human Aortic Smooth Muscle Cells.
Gáll T, Pethő D, Nagy A, Hendrik Z, Méhes G, Potor L, Gram M, Åkerström B, Smith A, Nagy P, Balla G, Balla J
Frontiers in physiology 2018;9:1595
Frontiers in physiology 2018;9:1595
Salvianolic Acid A Attenuates Endoplasmic Reticulum Stress and Protects Against Cholestasis-Induced Liver Fibrosis via the SIRT1/HSF1 Pathway.
Zhu J, Wang R, Xu T, Zhang S, Zhao Y, Li Z, Wang C, Zhou J, Gao D, Hu Y, Tian X, Yao J
Frontiers in pharmacology 2018;9:1277
Frontiers in pharmacology 2018;9:1277
Impact of GADD34 on Apoptosis of Tonsillar Mononuclear Cells from IgA Nephropathy Patients by Regulating Eif2α Phosphorylation.
Peng X, Yang T, He L, Chen X, Jiang Y, Zhang H, Liu H, Peng Y
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;50(6):2203-2215
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;50(6):2203-2215
MnTMPyP inhibits paraquat-induced pulmonary epithelial-like cell injury by inhibiting oxidative stress.
Xu Y, Sun D, Song C, Wang R, Dong X
The Journal of toxicological sciences 2018;43(9):545-555
The Journal of toxicological sciences 2018;43(9):545-555
Neuroprotective Effects of dl-3-n-Butylphthalide against Doxorubicin-Induced Neuroinflammation, Oxidative Stress, Endoplasmic Reticulum Stress, and Behavioral Changes.
Liao D, Xiang D, Dang R, Xu P, Wang J, Han W, Fu Y, Yao D, Cao L, Jiang P
Oxidative medicine and cellular longevity 2018;2018:9125601
Oxidative medicine and cellular longevity 2018;2018:9125601
Methane-Rich Saline Ameliorates Sepsis-Induced Acute Kidney Injury through Anti-Inflammation, Antioxidative, and Antiapoptosis Effects by Regulating Endoplasmic Reticulum Stress.
Jia Y, Li Z, Feng Y, Cui R, Dong Y, Zhang X, Xiang X, Qu K, Liu C, Zhang J
Oxidative medicine and cellular longevity 2018;2018:4756846
Oxidative medicine and cellular longevity 2018;2018:4756846
Palmitic Acid Downregulates Thyroglobulin (Tg), Sodium Iodide Symporter (NIS), and Thyroperoxidase (TPO) in Human Primary Thyrocytes: A Potential Mechanism by Which Lipotoxicity Affects Thyroid?
Zhao M, Zhang X, Gao L, Song Y, Xu C, Yu C, Shao S, Zhao J
International journal of endocrinology 2018;2018:4215848
International journal of endocrinology 2018;2018:4215848
Proscillaridin A Promotes Oxidative Stress and ER Stress, Inhibits STAT3 Activation, and Induces Apoptosis in A549 Lung Adenocarcinoma Cells.
Maryam A, Mehmood T, Yan Q, Li Y, Khan M, Ma T
Oxidative medicine and cellular longevity 2018;2018:3853409
Oxidative medicine and cellular longevity 2018;2018:3853409
Glucagon-Like Peptide-1 Mediates the Protective Effect of the Dipeptidyl Peptidase IV Inhibitor on Renal Fibrosis via Reducing the Phenotypic Conversion of Renal Microvascular Cells in Monocrotaline-Treated Rats.
Xu J, Wang J, Cheng Y, Li X, He M, Zhu J, Han H, Wei G, Kong H, Xie W, Wang H, Zuo X
BioMed research international 2018;2018:1864107
BioMed research international 2018;2018:1864107
Vitamin C alters the amount of specific endoplasmic reticulum associated proteins involved in lipid metabolism in the liver of mice synthesizing a nonfunctional Werner syndrome (Wrn) mutant protein.
Aumailley L, Roux-Dalvai F, Kelly I, Droit A, Lebel M
PloS one 2018;13(3):e0193170
PloS one 2018;13(3):e0193170
Amyotrophic lateral sclerosis (ALS) and Alzheimer's disease (AD) are characterised by differential activation of ER stress pathways: focus on UPR target genes.
Montibeller L, de Belleroche J
Cell stress & chaperones 2018 Sep;23(5):897-912
Cell stress & chaperones 2018 Sep;23(5):897-912
Ticagrelor protects against AngII-induced endothelial dysfunction by alleviating endoplasmic reticulum stress.
Wang X, Han X, Li M, Han Y, Zhang Y, Zhao S, Li Y
Microvascular research 2018 Sep;119:98-104
Microvascular research 2018 Sep;119:98-104
Selenoprotein S protects against adipocyte death through mediation of the IRE1α-sXBP1 pathway.
Men L, Yu S, Yao J, Li Y, Ren D, Du J
Biochemical and biophysical research communications 2018 Sep 18;503(4):2866-2871
Biochemical and biophysical research communications 2018 Sep 18;503(4):2866-2871
Phosphoglucomutase 1 inhibits hepatocellular carcinoma progression by regulating glucose trafficking.
Jin GZ, Zhang Y, Cong WM, Wu X, Wang X, Wu S, Wang S, Zhou W, Yuan S, Gao H, Yu G, Yang W
PLoS biology 2018 Oct;16(10):e2006483
PLoS biology 2018 Oct;16(10):e2006483
GanDouLing combined with Penicillamine improves cerebrovascular injury via PERK/eIF2α/CHOP endoplasmic reticulum stress pathway in the mouse model of Wilson's disease.
Chen Y, Zhang B, Cao S, Huang W, Liu N, Yang W
Bioscience reports 2018 Oct 31;38(5)
Bioscience reports 2018 Oct 31;38(5)
Tetrachlorobenzoquinone-Induced Nrf2 Confers Neuron-like PC12 Cells Resistance to Endoplasmic Reticulum Stress via Regulating Glutathione Synthesis and Protein Thiol Homeostasis.
Liu Z, Dong W, Yang B, Peng L, Xia X, Pu L, Zhang N, Song E, Song Y
Chemical research in toxicology 2018 Nov 19;31(11):1230-1239
Chemical research in toxicology 2018 Nov 19;31(11):1230-1239
Botulinum toxin B suppresses the pressure ulcer formation in cutaneous ischemia-reperfusion injury mouse model: Possible regulation of oxidative and endoplasmic reticulum stress.
Sekiguchi A, Motegi SI, Uchiyama A, Uehara A, Fujiwara C, Yamazaki S, Perera B, Nakamura H, Ogino S, Yokoyama Y, Akai R, Iwawaki T, Ishikawa O
Journal of dermatological science 2018 May;90(2):144-153
Journal of dermatological science 2018 May;90(2):144-153
A Novel Cx50 Insert Mutation from a Chinese Congenital Cataract Family Impairs Its Cellular Membrane Localization and Function.
Cui X, Zhou Z, Zhu K, Feng R, Han J, Li M, Wang S, Li J, Zhang J, Jiang Q, Zhang W, Mu H, Liu Y, Hu Y
DNA and cell biology 2018 May;37(5):449-456
DNA and cell biology 2018 May;37(5):449-456
Autophagy is a major mechanism for the dual effects of curcumin on renal cell carcinoma cells.
Deng Q, Liang L, Liu Q, Duan W, Jiang Y, Zhang L
European journal of pharmacology 2018 May 5;826:24-30
European journal of pharmacology 2018 May 5;826:24-30
Bcl-2 overexpression reduces cisplatin cytotoxicity by decreasing ER-mitochondrial Ca2+ signaling in SKOV3 cells.
Xu L, Xie Q, Qi L, Wang C, Xu N, Liu W, Yu Y, Li S, Xu Y
Oncology reports 2018 Mar;39(3):985-992
Oncology reports 2018 Mar;39(3):985-992
Effects of sevoflurane pretreatment on the apoptosis of rat H9c2 cardiomyocytes and the expression of GRP78.
Wang Z, Cui R, Wang K
Experimental and therapeutic medicine 2018 Mar;15(3):2818-2823
Experimental and therapeutic medicine 2018 Mar;15(3):2818-2823
Epigallocatechin-3-gallate alleviates bladder overactivity in a rat model with metabolic syndrome and ovarian hormone deficiency through mitochondria apoptosis pathways.
Lee YL, Lin KL, Wu BN, Chuang SM, Wu WJ, Lee YC, Ho WT, Juan YS
Scientific reports 2018 Mar 29;8(1):5358
Scientific reports 2018 Mar 29;8(1):5358
Advanced oxidation protein products aggravate cardiac remodeling via cardiomyocyte apoptosis in chronic kidney disease.
Feng W, Zhang K, Liu Y, Chen J, Cai Q, He W, Zhang Y, Wang MH, Wang J, Huang H
American journal of physiology. Heart and circulatory physiology 2018 Mar 1;314(3):H475-H483
American journal of physiology. Heart and circulatory physiology 2018 Mar 1;314(3):H475-H483
Serum vitamin C levels modulate the lifespan and endoplasmic reticulum stress response pathways in mice synthesizing a nonfunctional mutant WRN protein.
Aumailley L, Dubois MJ, Brennan TA, Garand C, Paquet ER, Pignolo RJ, Marette A, Lebel M
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2018 Jul;32(7):3623-3640
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2018 Jul;32(7):3623-3640
TRPV6 protects ER stress-induced apoptosis via ATF6α-TRPV6-JNK pathway in human embryonic stem cell-derived cardiomyocytes.
Li Z, Meng Z, Lu J, Chen FM, Wong WT, Tse G, Zheng C, Keung W, Tse K, Li RA, Jiang L, Yao X
Journal of molecular and cellular cardiology 2018 Jul;120:1-11
Journal of molecular and cellular cardiology 2018 Jul;120:1-11
ER-localized protein-Herpud1 is a new mediator of IL-4-induced macrophage polarization and migration.
Li Y, Xie Y, Hao J, Liu J, Ning Y, Tang Q, Ma M, Zhou H, Guan S, Zhou Q, Lv X
Experimental cell research 2018 Jul 15;368(2):167-173
Experimental cell research 2018 Jul 15;368(2):167-173
PGK1 and GRP78 overexpression correlates with clinical significance and poor prognosis in Chinese endometrial cancer patients.
Guo S, Xiao Y, Li D, Jiang Q, Zhu L, Lin D, Jiang H, Chen W, Wang L, Liu C, Fang W, Lin L
Oncotarget 2018 Jan 2;9(1):680-690
Oncotarget 2018 Jan 2;9(1):680-690
Brucella induces unfolded protein response and inflammatory response via GntR in alveolar macrophages.
Zhou D, Zhi FJ, Qi MZ, Bai FR, Zhang G, Li JM, Liu H, Chen HT, Lin PF, Tang KQ, Liu W, Jin YP, Wang AH
Oncotarget 2018 Jan 12;9(4):5184-5196
Oncotarget 2018 Jan 12;9(4):5184-5196
Excessive ER stress and the resulting autophagic flux dysfunction contribute to fluoride-induced neurotoxicity.
Niu Q, Chen J, Xia T, Li P, Zhou G, Xu C, Zhao Q, Dong L, Zhang S, Wang A
Environmental pollution (Barking, Essex : 1987) 2018 Feb;233:889-899
Environmental pollution (Barking, Essex : 1987) 2018 Feb;233:889-899
Young plasma reverses age-dependent alterations in hepatic function through the restoration of autophagy.
Liu A, Guo E, Yang J, Yang Y, Liu S, Jiang X, Hu Q, Dirsch O, Dahmen U, Zhang C, Gewirtz DA, Fang H
Aging cell 2018 Feb;17(1)
Aging cell 2018 Feb;17(1)
Protective Effects of Olive Leaf Extract on Acrolein-Exacerbated Myocardial Infarction via an Endoplasmic Reticulum Stress Pathway.
Xu Y, Wu L, Chen A, Xu C, Feng Q
International journal of molecular sciences 2018 Feb 7;19(2)
International journal of molecular sciences 2018 Feb 7;19(2)
Asiatic acid from Potentilla chinensis alleviates non-alcoholic fatty liver by regulating endoplasmic reticulum stress and lipid metabolism.
Wang D, Lao L, Pang X, Qiao Q, Pang L, Feng Z, Bai F, Sun X, Lin X, Wei J
International immunopharmacology 2018 Dec;65:256-267
International immunopharmacology 2018 Dec;65:256-267
Hepatic Mitochondrial Defects in a Nonalcoholic Fatty Liver Disease Mouse Model Are Associated with Increased Degradation of Oxidative Phosphorylation Subunits.
Lee K, Haddad A, Osme A, Kim C, Borzou A, Ilchenko S, Allende D, Dasarathy S, McCullough A, Sadygov RG, Kasumov T
Molecular & cellular proteomics : MCP 2018 Dec;17(12):2371-2386
Molecular & cellular proteomics : MCP 2018 Dec;17(12):2371-2386
Perigestational exposure to low doses of PBDE-47 induces excessive ER stress, defective autophagy and the resultant apoptosis contributing to maternal thyroid toxicity.
Li P, Liu L, Zhou G, Tian Z, Luo C, Xia T, Chen J, Niu Q, Dong L, Zhao Q, Wang A, Zhang S
The Science of the total environment 2018 Dec 15;645:363-371
The Science of the total environment 2018 Dec 15;645:363-371
Mini-peptide RPL41 attenuated retinal neovascularization by inducing degradation of ATF4 in oxygen-induced retinopathy mice.
Geng W, Qin F, Ren J, Xiao S, Wang A
Experimental cell research 2018 Aug 15;369(2):243-250
Experimental cell research 2018 Aug 15;369(2):243-250
CHOP induces apoptosis by affecting brain iron metabolism in rats with subarachnoid hemorrhage.
Zhao J, Xiang X, Zhang H, Jiang D, Liang Y, Qing W, Liu L, Zhao Q, He Z
Experimental neurology 2018 Apr;302:22-33
Experimental neurology 2018 Apr;302:22-33
Downregulation of reticulocalbin-1 differentially facilitates apoptosis and necroptosis in human prostate cancer cells.
Liu X, Zhang N, Wang D, Zhu D, Yuan Q, Zhang X, Qian L, Niu H, Lu Y, Ren G, Tian K, Yuan H
Cancer science 2018 Apr;109(4):1147-1157
Cancer science 2018 Apr;109(4):1147-1157
Hepatic loss of Lissencephaly 1 (Lis1) induces fatty liver and accelerates liver tumorigenesis in mice.
Li X, Liu L, Li R, Wu A, Lu J, Wu Q, Jia J, Zhao M, Song H
The Journal of biological chemistry 2018 Apr 6;293(14):5160-5171
The Journal of biological chemistry 2018 Apr 6;293(14):5160-5171
Exogenous H2S restores ischemic post-conditioning-induced cardioprotection through inhibiting endoplasmic reticulum stress in the aged cardiomyocytes.
Sun W, Yang J, Zhang Y, Xi Y, Wen X, Yuan D, Wang Y, Wei C, Wang R, Wu L, Li H, Xu C
Cell & bioscience 2017;7:67
Cell & bioscience 2017;7:67
Hydrogen Gas Attenuates Myocardial Ischemia Reperfusion Injury Independent of Postconditioning in Rats by Attenuating Endoplasmic Reticulum Stress-Induced Autophagy.
Gao Y, Yang H, Chi J, Xu Q, Zhao L, Yang W, Liu W, Yang W
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2017;43(4):1503-1514
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2017;43(4):1503-1514
Endoplasmic Reticulum Stress Is Involved in Cochlear Cell Apoptosis in a Cisplatin-Induced Ototoxicity Rat Model.
Zong S, Liu T, Wan F, Chen P, Luo P, Xiao H
Audiology & neuro-otology 2017;22(3):160-168
Audiology & neuro-otology 2017;22(3):160-168
TBHQ Alleviated Endoplasmic Reticulum Stress-Apoptosis and Oxidative Stress by PERK-Nrf2 Crosstalk in Methamphetamine-Induced Chronic Pulmonary Toxicity.
Wang Y, Gu YH, Liu M, Bai Y, Liang LY, Wang HL
Oxidative medicine and cellular longevity 2017;2017:4310475
Oxidative medicine and cellular longevity 2017;2017:4310475
Involvement of endoplasmic reticulum stress in formalin-induced pain is attenuated by 4-phenylbutyric acid.
Zhou F, Zhang W, Zhou J, Li M, Zhong F, Zhang Y, Liu Y, Wang Y
Journal of pain research 2017;10:653-662
Journal of pain research 2017;10:653-662
GRP78 plays an integral role in tumor cell inflammation-related migration induced by M2 macrophages.
Zhang L, Li Z, Ding G, La X, Yang P, Li Z
Cellular signalling 2017 Sep;37:136-148
Cellular signalling 2017 Sep;37:136-148
The meta and bioinformatics analysis of GRP78 expression in gastric cancer.
Zheng HC, Gong BC, Zhao S
Oncotarget 2017 Sep 22;8(42):73017-73028
Oncotarget 2017 Sep 22;8(42):73017-73028
Inhibition of Endoplasmic Reticulum Stress Alleviates Lung Injury Induced by Brain Death.
Tang H, Zhang J, Cao S, Yan B, Fang H, Zhang H, Guo W, Zhang S
Inflammation 2017 Oct;40(5):1664-1671
Inflammation 2017 Oct;40(5):1664-1671
CNPY2 is a key initiator of the PERK-CHOP pathway of the unfolded protein response.
Hong F, Liu B, Wu BX, Morreall J, Roth B, Davies C, Sun S, Diehl JA, Li Z
Nature structural & molecular biology 2017 Oct;24(10):834-839
Nature structural & molecular biology 2017 Oct;24(10):834-839
Therapeutic effects of L-Cysteine in newborn mice subjected to hypoxia-ischemia brain injury via the CBS/H2S system: Role of oxidative stress and endoplasmic reticulum stress.
Liu S, Xin D, Wang L, Zhang T, Bai X, Li T, Xie Y, Xue H, Bo S, Liu D, Wang Z
Redox biology 2017 Oct;13:528-540
Redox biology 2017 Oct;13:528-540
Hepatitis B virus X protein inhibits apoptosis by modulating endoplasmic reticulum stress response.
Li J, He J, Fu Y, Hu X, Sun LQ, Huang Y, Fan X
Oncotarget 2017 Nov 10;8(56):96027-96034
Oncotarget 2017 Nov 10;8(56):96027-96034
PCSK9 regulates apoptosis in human lung adenocarcinoma A549 cells via endoplasmic reticulum stress and mitochondrial signaling pathways.
Xu X, Cui Y, Cao L, Zhang Y, Yin Y, Hu X
Experimental and therapeutic medicine 2017 May;13(5):1993-1999
Experimental and therapeutic medicine 2017 May;13(5):1993-1999
Renin-angiotensin system activation accelerates atherosclerosis in experimental renal failure by promoting endoplasmic reticulum stress-related inflammation.
Yang J, Zhang X, Yu X, Tang W, Gan H
International journal of molecular medicine 2017 Mar;39(3):613-621
International journal of molecular medicine 2017 Mar;39(3):613-621
Calcium release induced by 2-pyridinecarboxaldehyde thiosemicarbazone and its copper complex contributes to tumor cell death.
Fu Y, Liu Y, Wang J, Li C, Zhou S, Yang Y, Zhou P, Lu C, Li C
Oncology reports 2017 Mar;37(3):1662-1670
Oncology reports 2017 Mar;37(3):1662-1670
Identification of Novel SCIRR69-Interacting Proteins During ER Stress Using SILAC-Immunoprecipitation Quantitative Proteomics Approach.
Chen Y, Liu Y, Lin S, Yang S, Que H, Liu S
Neuromolecular medicine 2017 Mar;19(1):81-93
Neuromolecular medicine 2017 Mar;19(1):81-93
Exogenous H2S regulates endoplasmic reticulum-mitochondria cross-talk to inhibit apoptotic pathways in STZ-induced type I diabetes.
Yang F, Yu X, Li T, Wu J, Zhao Y, Liu J, Sun A, Dong S, Wu J, Zhong X, Xu C, Lu F, Zhang W
American journal of physiology. Endocrinology and metabolism 2017 Mar 1;312(3):E190-E203
American journal of physiology. Endocrinology and metabolism 2017 Mar 1;312(3):E190-E203
Cr(VI) induces cytotoxicity in vitro through activation of ROS-mediated endoplasmic reticulum stress and mitochondrial dysfunction via the PI3K/Akt signaling pathway.
Zhang Y, Xiao F, Liu X, Liu K, Zhou X, Zhong C
Toxicology in vitro : an international journal published in association with BIBRA 2017 Jun;41:232-244
Toxicology in vitro : an international journal published in association with BIBRA 2017 Jun;41:232-244
Curcumin enhances the effects of irinotecan on colorectal cancer cells through the generation of reactive oxygen species and activation of the endoplasmic reticulum stress pathway.
Huang YF, Zhu DJ, Chen XW, Chen QK, Luo ZT, Liu CC, Wang GX, Zhang WJ, Liao NZ
Oncotarget 2017 Jun 20;8(25):40264-40275
Oncotarget 2017 Jun 20;8(25):40264-40275
Cell surface GRP78 facilitates hepatoma cells proliferation and migration by activating IGF-IR.
Yin Y, Chen C, Chen J, Zhan R, Zhang Q, Xu X, Li D, Li M
Cellular signalling 2017 Jul;35:154-162
Cellular signalling 2017 Jul;35:154-162
Endoplasmic reticulum stress and apoptosis via PERK-eIF2α-CHOP signaling in the methamphetamine-induced chronic pulmonary injury.
Gu YH, Wang Y, Bai Y, Liu M, Wang HL
Environmental toxicology and pharmacology 2017 Jan;49:194-201
Environmental toxicology and pharmacology 2017 Jan;49:194-201
GALNT6 Stabilizes GRP78 Protein by O-glycosylation and Enhances its Activity to Suppress Apoptosis Under Stress Condition.
Lin J, Chung S, Ueda K, Matsuda K, Nakamura Y, Park JH
Neoplasia (New York, N.Y.) 2017 Jan;19(1):43-53
Neoplasia (New York, N.Y.) 2017 Jan;19(1):43-53
Knockdown of histidine-rich calcium-binding protein (HRC) suppresses liver fibrosis by inhibiting the activation of hepatic stellate cells.
Liu J, Li M, Gong J, Han P, Wang Y, Li D, Tian D, Liao J
Biology open 2017 Jan 15;6(1):29-34
Biology open 2017 Jan 15;6(1):29-34
A positive feedback loop between GRP78 and VPS34 is critical for GRP78-mediated autophagy in cancer cells.
Wang Y, Wu H, Li Z, Yang P, Li Z
Experimental cell research 2017 Feb 1;351(1):24-35
Experimental cell research 2017 Feb 1;351(1):24-35
Protective effect of mesenchymal stem cells on the pressure ulcer formation by the regulation of oxidative and endoplasmic reticulum stress.
Motegi SI, Sekiguchi A, Uchiyama A, Uehara A, Fujiwara C, Yamazaki S, Perera B, Nakamura H, Ogino S, Yokoyama Y, Akai R, Iwawaki T, Ishikawa O
Scientific reports 2017 Dec 7;7(1):17186
Scientific reports 2017 Dec 7;7(1):17186
Elevated urinary CRELD2 is associated with endoplasmic reticulum stress-mediated kidney disease.
Kim Y, Park SJ, Manson SR, Molina CA, Kidd K, Thiessen-Philbrook H, Perry RJ, Liapis H, Kmoch S, Parikh CR, Bleyer AJ, Chen YM
JCI insight 2017 Dec 7;2(23)
JCI insight 2017 Dec 7;2(23)
Autoantibodies against glucose-regulated protein 78 as serological biomarkers in metastatic and recurrent hepatocellular carcinoma.
Ying X, Han SX, He CC, Zhou CY, Dong YP, Cai MJ, Sui X, Ma CX, Sun X, Zhang YY, Gou WL, Mason C, Zhu Q
Oncotarget 2017 Apr 11;8(15):24828-24839
Oncotarget 2017 Apr 11;8(15):24828-24839
Quantitative Proteomic Profiling the Molecular Signatures of Annexin A5 in Lung Squamous Carcinoma Cells.
Sun B, Bai Y, Zhang L, Gong L, Qi X, Li H, Wang F, Chi X, Jiang Y, Shao S
PloS one 2016;11(9):e0163622
PloS one 2016;11(9):e0163622
A Health Threat to Bystanders Living in the Homes of Smokers: How Smoke Toxins Deposited on Surfaces Can Cause Insulin Resistance.
Adhami N, Starck SR, Flores C, Martins Green M
PloS one 2016;11(3):e0149510
PloS one 2016;11(3):e0149510
Dysfunctional tubular endoplasmic reticulum constitutes a pathological feature of Alzheimer's disease.
Sharoar MG, Shi Q, Ge Y, He W, Hu X, Perry G, Zhu X, Yan R
Molecular psychiatry 2016 Sep;21(9):1263-71
Molecular psychiatry 2016 Sep;21(9):1263-71
Activating Transcription Factor 4 (ATF4)-ATF3-C/EBP Homologous Protein (CHOP) Cascade Shows an Essential Role in the ER Stress-Induced Sensitization of Tetrachlorobenzoquinone-Challenged PC12 Cells to ROS-Mediated Apoptosis via Death Receptor 5 (DR5) Signaling.
Liu Z, Shi Q, Song X, Wang Y, Wang Y, Song E, Song Y
Chemical research in toxicology 2016 Sep 19;29(9):1510-8
Chemical research in toxicology 2016 Sep 19;29(9):1510-8
Hydrogen-rich saline mediates neuroprotection through the regulation of endoplasmic reticulum stress and autophagy under hypoxia-ischemia neonatal brain injury in mice.
Bai X, Liu S, Yuan L, Xie Y, Li T, Wang L, Wang X, Zhang T, Qin S, Song G, Ge L, Wang Z
Brain research 2016 Sep 1;1646:410-417
Brain research 2016 Sep 1;1646:410-417
Design, purification and assessment of GRP78 binding peptide-linked Subunit A of Subtilase cytotoxic for targeting cancer cells.
Zhang L, Li Z, Shi T, La X, Li H, Li Z
BMC biotechnology 2016 Sep 1;16(1):65
BMC biotechnology 2016 Sep 1;16(1):65
Palmitic acid aggravates inflammation of pancreatic acinar cells by enhancing unfolded protein response induced CCAAT-enhancer-binding protein β-CCAAT-enhancer-binding protein α activation.
Wu J, Hu G, Lu Y, Zheng J, Chen J, Wang X, Zeng Y
The international journal of biochemistry & cell biology 2016 Oct;79:181-193
The international journal of biochemistry & cell biology 2016 Oct;79:181-193
Chronic alpha-linolenic acid treatment alleviates age-associated neuropathology: Roles of PERK/eIF2α signaling pathway.
Gao H, Yan P, Zhang S, Nie S, Huang F, Han H, Deng Q, Huang Q, Yang W, Wu H, Yao P, Ye K, Xu J, Liu L
Brain, behavior, and immunity 2016 Oct;57:314-325
Brain, behavior, and immunity 2016 Oct;57:314-325
Rifampicin-induced injury in L02 cells is alleviated by 4-PBA via inhibition of the PERK-ATF4-CHOP pathway.
Zhang W, Chen L, Shen Y, Xu J
Toxicology in vitro : an international journal published in association with BIBRA 2016 Oct;36:186-196
Toxicology in vitro : an international journal published in association with BIBRA 2016 Oct;36:186-196
Cytotoxicity of 11-epi-Sinulariolide Acetate Isolated from Cultured Soft Corals on HA22T Cells through the Endoplasmic Reticulum Stress Pathway and Mitochondrial Dysfunction.
Lin JJ, Wang RY, Chen JC, Chiu CC, Liao MH, Wu YJ
International journal of molecular sciences 2016 Oct 27;17(11)
International journal of molecular sciences 2016 Oct 27;17(11)
Alpha-lipoic acid defends homocysteine-induced endoplasmic reticulum and oxidative stress in HAECs.
Hu H, Wang C, Jin Y, Meng Q, Liu Q, Liu K, Sun H
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2016 May;80:63-72
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2016 May;80:63-72
Cyanidin 3-O-β-Glucoside Ameliorates Ethanol-Induced Acute Liver Injury by Attenuating Oxidative Stress and Apoptosis: The Role of SIRT1/FOXO1 Signaling.
Liu J, Zhou J, Wu Z, Wang X, Liu L, Yao C
Alcoholism, clinical and experimental research 2016 Mar;40(3):457-66
Alcoholism, clinical and experimental research 2016 Mar;40(3):457-66
Japanese encephalitis virus induces apoptosis by the IRE1/JNK pathway of ER stress response in BHK-21 cells.
Huang M, Xu A, Wu X, Zhang Y, Guo Y, Guo F, Pan Z, Kong L
Archives of virology 2016 Mar;161(3):699-703
Archives of virology 2016 Mar;161(3):699-703
Translation from the 5' untranslated region shapes the integrated stress response.
Starck SR, Tsai JC, Chen K, Shodiya M, Wang L, Yahiro K, Martins-Green M, Shastri N, Walter P
Science (New York, N.Y.) 2016 Jan 29;351(6272):aad3867
Science (New York, N.Y.) 2016 Jan 29;351(6272):aad3867
The ATF6 pathway of the ER stress response contributes to enhanced viability in glioblastoma.
Dadey DY, Kapoor V, Khudanyan A, Urano F, Kim AH, Thotala D, Hallahan DE
Oncotarget 2016 Jan 12;7(2):2080-92
Oncotarget 2016 Jan 12;7(2):2080-92
Effects of Placental Ischemia Are Attenuated by 1,25-Dihydroxyvitamin D Treatment and Associated with Reduced Apoptosis and Increased Autophagy.
Tian X, Ma S, Wang Y, Hou L, Shi Y, Yao M, Wang X, Zhang H, Jiang L
DNA and cell biology 2016 Feb;35(2):59-70
DNA and cell biology 2016 Feb;35(2):59-70
ABT737 reverses cisplatin resistance by regulating ER-mitochondria Ca2+ signal transduction in human ovarian cancer cells.
Xie Q, Su J, Jiao B, Shen L, Ma L, Qu X, Yu C, Jiang X, Xu Y, Sun L
International journal of oncology 2016 Dec;49(6):2507-2519
International journal of oncology 2016 Dec;49(6):2507-2519
Resveratrol Induces Cancer Cell Apoptosis through MiR-326/PKM2-Mediated ER Stress and Mitochondrial Fission.
Wu H, Wang Y, Wu C, Yang P, Li H, Li Z
Journal of agricultural and food chemistry 2016 Dec 14;64(49):9356-9367
Journal of agricultural and food chemistry 2016 Dec 14;64(49):9356-9367
Cathelicidin PR-39 peptide inhibits hypoxia/reperfusion-induced kidney cell apoptosis by suppression of the endoplasmic reticulum-stress pathway.
Liu J, Xue W, Xiang H, Zheng J, Zhao Y, Jiao L, Jiao Z
Acta biochimica et biophysica Sinica 2016 Aug;48(8):714-22
Acta biochimica et biophysica Sinica 2016 Aug;48(8):714-22
Endoplasmic Reticulum Stress May Play a Pivotal Role in Lipid Metabolic Disorders in a Novel Mouse Model of Subclinical Hypothyroidism.
Zhou L, Ding S, Li Y, Wang L, Chen W, Bo T, Wu K, Li C, Liu X, Zhao J, Xu C, Gao L
Scientific reports 2016 Aug 19;6:31381
Scientific reports 2016 Aug 19;6:31381
PACE4 regulates apoptosis in human prostate cancer cells via endoplasmic reticulum stress and mitochondrial signaling pathways.
Yao Z, Sun B, Hong Q, Yan J, Mu D, Li J, Sheng H, Guo H
Drug design, development and therapy 2015;9:5911-23
Drug design, development and therapy 2015;9:5911-23
Metabolic and Phenotypic Differences between Mice Producing a Werner Syndrome Helicase Mutant Protein and Wrn Null Mice.
Aumailley L, Garand C, Dubois MJ, Johnson FB, Marette A, Lebel M
PloS one 2015;10(10):e0140292
PloS one 2015;10(10):e0140292
Impaired unfolded protein response in the degeneration of cochlea cells in a mouse model of age-related hearing loss.
Wang W, Sun Y, Chen S, Zhou X, Wu X, Kong W, Kong W
Experimental gerontology 2015 Oct;70:61-70
Experimental gerontology 2015 Oct;70:61-70
IRE1 prevents endoplasmic reticulum membrane permeabilization and cell death under pathological conditions.
Kanekura K, Ma X, Murphy JT, Zhu LJ, Diwan A, Urano F
Science signaling 2015 Jun 23;8(382):ra62
Science signaling 2015 Jun 23;8(382):ra62
Polychlorinated biphenyl quinone induces endoplasmic reticulum stress, unfolded protein response, and calcium release.
Xu D, Su C, Song X, Shi Q, Fu J, Hu L, Xia X, Song E, Song Y
Chemical research in toxicology 2015 Jun 15;28(6):1326-37
Chemical research in toxicology 2015 Jun 15;28(6):1326-37
Legionella suppresses the host unfolded protein response via multiple mechanisms.
Treacy-Abarca S, Mukherjee S
Nature communications 2015 Jul 29;6:7887
Nature communications 2015 Jul 29;6:7887
Knockdown of glucose-regulated protein 78/binding immunoglobulin heavy chain protein expression by asymmetric small interfering RNA induces apoptosis in prostate cancer cells and attenuates migratory capability.
Lu T, Yang W, Wang Z, Hu Z, Zeng X, Yang C, Wang Y, Zhang Y, Li F, Liu Z, Wang D, Ye Z
Molecular medicine reports 2015 Jan;11(1):249-56
Molecular medicine reports 2015 Jan;11(1):249-56
Potent effects of the total saponins from Dioscorea nipponica Makino against streptozotocin-induced type 2 diabetes mellitus in rats.
Yu H, Zheng L, Xu L, Yin L, Lin Y, Li H, Liu K, Peng J
Phytotherapy research : PTR 2015 Feb;29(2):228-40
Phytotherapy research : PTR 2015 Feb;29(2):228-40
Impact of vitamin C on the cardiometabolic and inflammatory profiles of mice lacking a functional Werner syndrome protein helicase.
Aumailley L, Dubois MJ, Garand C, Marette A, Lebel M
Experimental gerontology 2015 Dec;72:192-203
Experimental gerontology 2015 Dec;72:192-203
Ketamine-induced ulcerative cystitis and bladder apoptosis involve oxidative stress mediated by mitochondria and the endoplasmic reticulum.
Liu KM, Chuang SM, Long CY, Lee YL, Wang CC, Lu MC, Lin RJ, Lu JH, Jang MY, Wu WJ, Ho WT, Juan YS
American journal of physiology. Renal physiology 2015 Aug 15;309(4):F318-31
American journal of physiology. Renal physiology 2015 Aug 15;309(4):F318-31
Protective effects of dioscin against alcohol-induced liver injury.
Xu T, Zheng L, Xu L, Yin L, Qi Y, Xu Y, Han X, Peng J
Archives of toxicology 2014 Mar;88(3):739-53
Archives of toxicology 2014 Mar;88(3):739-53
The resveratrol attenuates ethanol-induced hepatocyte apoptosis via inhibiting ER-related caspase-12 activation and PDE activity in vitro.
Liu LQ, Fan ZQ, Tang YF, Ke ZJ
Alcoholism, clinical and experimental research 2014 Mar;38(3):683-93
Alcoholism, clinical and experimental research 2014 Mar;38(3):683-93
Exposure to tributyltin induces endoplasmic reticulum stress and the unfolded protein response in zebrafish.
Komoike Y, Matsuoka M
Aquatic toxicology (Amsterdam, Netherlands) 2013 Oct 15;142-143:221-9
Aquatic toxicology (Amsterdam, Netherlands) 2013 Oct 15;142-143:221-9
ABCG1 deficiency promotes endothelial apoptosis by endoplasmic reticulum stress-dependent pathway.
Xue J, Wei J, Dong X, Zhu C, Li Y, Song A, Liu Z
The journal of physiological sciences : JPS 2013 Nov;63(6):435-44
The journal of physiological sciences : JPS 2013 Nov;63(6):435-44
Protein kinase RNA-like endoplasmic reticulum kinase (PERK) signaling pathway plays a major role in reactive oxygen species (ROS)-mediated endoplasmic reticulum stress-induced apoptosis in diabetic cardiomyopathy.
Liu ZW, Zhu HT, Chen KL, Dong X, Wei J, Qiu C, Xue JH
Cardiovascular diabetology 2013 Nov 2;12:158
Cardiovascular diabetology 2013 Nov 2;12:158
The alteration of protein profile induced by cigarette smoking via oxidative stress in mice epididymis.
Zhu Z, Xu W, Dai J, Chen X, Zhao X, Fang P, Yang F, Tang M, Wang Z, Wang L, Ma D, Qaio Z
The international journal of biochemistry & cell biology 2013 Mar;45(3):571-82
The international journal of biochemistry & cell biology 2013 Mar;45(3):571-82
Upregulation of phosphorylated HSP27, PRDX2, GRP75, GRP78 and GRP94 in acquired middle ear cholesteatoma growth.
Ho KY, Yeh TS, Huang HH, Hung KF, Chai CY, Chen WT, Tsai SM, Chang NC, Chien CY, Wang HM, Wu YJ
International journal of molecular sciences 2013 Jul 11;14(7):14439-59
International journal of molecular sciences 2013 Jul 11;14(7):14439-59
Protective effects of the total saponins from Rosa laevigata Michx fruit against carbon tetrachloride-induced acute liver injury in mice.
Dong D, Zhang S, Yin L, Tang X, Xu Y, Han X, Qi Y, Peng J
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2013 Dec;62:120-30
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2013 Dec;62:120-30
Selenium deficiency is associated with endoplasmic reticulum stress in a rat model of cardiac malfunction.
Wang SQ, Niu XL, Liu ZW, Zhu YH, Gao DF
Biological trace element research 2013 Dec;156(1-3):196-201
Biological trace element research 2013 Dec;156(1-3):196-201
Cell intrinsic role of COX-2 in pancreatic cancer development.
Hill R, Li Y, Tran LM, Dry S, Calvopina JH, Garcia A, Kim C, Wang Y, Donahue TR, Herschman HR, Wu H
Molecular cancer therapeutics 2012 Oct;11(10):2127-37
Molecular cancer therapeutics 2012 Oct;11(10):2127-37
Profiling of differentially expressed proteins in stage IV colorectal cancers with good and poor outcomes.
Kim HJ, Kang UB, Lee H, Jung JH, Lee ST, Yu MH, Kim H, Lee C
Journal of proteomics 2012 Jun 6;75(10):2983-97
Journal of proteomics 2012 Jun 6;75(10):2983-97
Proteomic analysis of anti-tumor effects of 11-dehydrosinulariolide on CAL-27 cells.
Liu CI, Chen CC, Chen JC, Su JH, Huang HH, Chen JY, Wu YJ
Marine drugs 2011;9(7):1254-72
Marine drugs 2011;9(7):1254-72
Co-chaperone HSJ1a dually regulates the proteasomal degradation of ataxin-3.
Gao XC, Zhou CJ, Zhou ZR, Zhang YH, Zheng XM, Song AX, Hu HY
PloS one 2011;6(5):e19763
PloS one 2011;6(5):e19763
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HepG2 cells were subjected to SDS PAGE followed by western blot with 11587-1-AP(GRP78,BIP antibody) at dilution of 1:1000
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The GRP78/BIP antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human GRP78/BIP. This antibody recognizes human, mouse, rat antigen. The GRP78/BIP antibody has been validated for the following applications: ELISA, WB, IP, IF, IHC analysis.
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- IP Result of anti-GRP78,BIP (IP:11587-1-AP, 3ug; Detection:11587-1-AP 1:1000) with MCF-7 cells lysate 3250ug.
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human pancreas cancer using 11587-1-AP(GRP78,BIP antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human pancreas cancer using 11587-1-AP(GRP78,BIP antibody) at dilution of 1:50 (under 40x lens)
- Sample type
- tissue