H00003309-A01

antibody from Abnova Corporation

Targeting: HSPA5 BiP, GRP78

Western blot (Supportive data in Antibodypedia)

Antibody Data

Product number

H00003309-A01

Provider

Abnova Corporation

Proper citation

Abnova Corporation Cat#H00003309-A01, RRID:AB_606416

Product name

HSPA5 polyclonal antibody (A01)

Antibody type

Polyclonal

Description

Mouse polyclonal antibody raised against a full-length recombinant HSPA5.

Antigen sequence

EEEDKKEDVGTVVGIDLGTTYSCVGVFKNGRVEII
ANDQGNRITPSYVAFTPEGERLIGDAAKNQLTSNP
ENTVFDAKRLIGRTWNDPSVQQDIKFLPFKVVEKK
TKPYIQVDIGGGQTKTFAPEEISAMVLTKMKETAE
AYLGKKVTHAVVTVPAYFNDAQRQATKDAGTIAGL
NVMRIINEPTAAAIAYGLDKREGEKNILVFDLGGG
TFDVSLLTIDNGVFEVVATNGDTHLGGEDFDQRVM
EHFIKLYKKKTGKDVRKDNRAVQKLRREVEKAKRA
LSSQHQARIEIESFYEGEDFSETLTRAKFEELNMD
LFRSTMKPVQKVLEDSDLKKSDIDEIVLVGGSTRI
PKIQQLVKEFFNGKEPSRGINPDEAVAYGAAVQAG
VLSGDQDTGDLVLLDVCPLTLGIETVGGVMTKLIP
RNTVVPTKKSQIFSTASDNQPTVTIKVYEGERPLT
KDNHLLGTFDLTGIPPAPRGVPQIEVTFEIDVNGI
LRVTAEDKGTGNKNKITITNDQNRLTPEEIERMVN
DAEKFAEEDKKLKERIDTRNELESYAYSLKNQIGD
KEKLGGKLSSEDKETMEKAVEEKIEWLESHQDADI
EDFKAKKKELEEIVQPIISKLYGSAGPPPTGEEDT
AEKDEL


Storage

Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References

Submitted references

GRP-78 secreted by tumor cells blocks the antiangiogenic activity of bortezomib.

Kern J, Untergasser G, Zenzmaier C, Sarg B, Gastl G, Gunsilius E, Steurer M
Blood 2009 Oct 29;114(18):3960-7

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Proteinuria and hyperglycemia induce endoplasmic reticulum stress.

Lindenmeyer MT, Rastaldi MP, Ikehata M, Neusser MA, Kretzler M, Cohen CD, Schlöndorff D
Journal of the American Society of Nephrology : JASN 2008 Nov;19(11):2225-36

Western blot

Supportive validation

Submitted by

Abnova Corporation (provider)

Main image

Experimental details

HSPA5 polyclonal antibody (A01), Lot # 050920JC01 Western Blot analysis of HSPA5 expression in MES-SA/Dx5 ( Cat # L021V1 ).