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- Antibody Data
- Antigen structure
- References [13]
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- Validations
- Immunocytochemistry [1]
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- Product number
- ADI-SPA-826-F - Provider product page
- Provider
- Enzo Life Sciences
- Product name
- Grp 78 BiP, pAb
- Antibody type
- Polyclonal
- Antigen
- Synthetic peptide
- Description
- Protein A affinity purified. Liquid. In PBS containing 50% glycerol and 0.09% sodium azide.
Submitted references The HSP90 inhibitor, 17AAG, protects the intestinal stem cell niche and inhibits graft versus host disease development.
A Versatile Cell Death Screening Assay Using Dye-Stained Cells and Multivariate Image Analysis.
miR-184 Regulates Pancreatic β-Cell Function According to Glucose Metabolism.
ERp29, an endoplasmic reticulum secretion factor is involved in the growth of breast tumor xenografts.
Nerve growth factor blocks thapsigargin-induced apoptosis at the level of the mitochondrion via regulation of Bim.
Small heat-shock proteins select deltaF508-CFTR for endoplasmic reticulum-associated degradation.
gamma-Secretase activity requires the presenilin-dependent trafficking of nicastrin through the Golgi apparatus but not its complex glycosylation.
Mutant SOD1 linked to familial amyotrophic lateral sclerosis, but not wild-type SOD1, induces ER stress in COS7 cells and transgenic mice.
Bax plays a pivotal role in thapsigargin-induced apoptosis of human colon cancer HCT116 cells by controlling Smac/Diablo and Omi/HtrA2 release from mitochondria.
The protein kinase/endoribonuclease IRE1alpha that signals the unfolded protein response has a luminal N-terminal ligand-independent dimerization domain.
Differential interaction of molecular chaperones with procollagen I and type IV collagen in corneal endothelial cells.
Nitric oxide-induced apoptosis in RAW 264.7 macrophages is mediated by endoplasmic reticulum stress pathway involving ATF6 and CHOP.
Truncation releases olfactory receptors from the endoplasmic reticulum of heterologous cells.
Joly AL, Deepti A, Seignez A, Goloudina A, Hebrard S, Schmitt E, Richaud S, Fourmaux E, Hammann A, Collura A, Svrcek M, Jego G, Robinet E, Solary E, Demidov O, Kohli E, Garrido C
Oncogene 2015 Sep 14;
Oncogene 2015 Sep 14;
A Versatile Cell Death Screening Assay Using Dye-Stained Cells and Multivariate Image Analysis.
Collins TJ, Ylanko J, Geng F, Andrews DW
Assay and drug development technologies 2015 Nov;13(9):547-57
Assay and drug development technologies 2015 Nov;13(9):547-57
miR-184 Regulates Pancreatic β-Cell Function According to Glucose Metabolism.
Tattikota SG, Rathjen T, Hausser J, Khedkar A, Kabra UD, Pandey V, Sury M, Wessels HH, Mollet IG, Eliasson L, Selbach M, Zinzen RP, Zavolan M, Kadener S, Tschöp MH, Jastroch M, Friedländer MR, Poy MN
The Journal of biological chemistry 2015 Aug 14;290(33):20284-94
The Journal of biological chemistry 2015 Aug 14;290(33):20284-94
ERp29, an endoplasmic reticulum secretion factor is involved in the growth of breast tumor xenografts.
Mkrtchian S, Baryshev M, Sargsyan E, Chatzistamou I, Volakaki AA, Chaviaras N, Pafiti A, Triantafyllou A, Kiaris H
Molecular carcinogenesis 2008 Nov;47(11):886-92
Molecular carcinogenesis 2008 Nov;47(11):886-92
Nerve growth factor blocks thapsigargin-induced apoptosis at the level of the mitochondrion via regulation of Bim.
Szegezdi E, Herbert KR, Kavanagh ET, Samali A, Gorman AM
Journal of cellular and molecular medicine 2008 Dec;12(6A):2482-96
Journal of cellular and molecular medicine 2008 Dec;12(6A):2482-96
Small heat-shock proteins select deltaF508-CFTR for endoplasmic reticulum-associated degradation.
Ahner A, Nakatsukasa K, Zhang H, Frizzell RA, Brodsky JL
Molecular biology of the cell 2007 Mar;18(3):806-14
Molecular biology of the cell 2007 Mar;18(3):806-14
gamma-Secretase activity requires the presenilin-dependent trafficking of nicastrin through the Golgi apparatus but not its complex glycosylation.
Herreman A, Van Gassen G, Bentahir M, Nyabi O, Craessaerts K, Mueller U, Annaert W, De Strooper B
Journal of cell science 2003 Mar 15;116(Pt 6):1127-36
Journal of cell science 2003 Mar 15;116(Pt 6):1127-36
Mutant SOD1 linked to familial amyotrophic lateral sclerosis, but not wild-type SOD1, induces ER stress in COS7 cells and transgenic mice.
Tobisawa S, Hozumi Y, Arawaka S, Koyama S, Wada M, Nagai M, Aoki M, Itoyama Y, Goto K, Kato T
Biochemical and biophysical research communications 2003 Apr 4;303(2):496-503
Biochemical and biophysical research communications 2003 Apr 4;303(2):496-503
Bax plays a pivotal role in thapsigargin-induced apoptosis of human colon cancer HCT116 cells by controlling Smac/Diablo and Omi/HtrA2 release from mitochondria.
Yamaguchi H, Bhalla K, Wang HG
Cancer research 2003 Apr 1;63(7):1483-9
Cancer research 2003 Apr 1;63(7):1483-9
The protein kinase/endoribonuclease IRE1alpha that signals the unfolded protein response has a luminal N-terminal ligand-independent dimerization domain.
Liu CY, Wong HN, Schauerte JA, Kaufman RJ
The Journal of biological chemistry 2002 May 24;277(21):18346-56
The Journal of biological chemistry 2002 May 24;277(21):18346-56
Differential interaction of molecular chaperones with procollagen I and type IV collagen in corneal endothelial cells.
Ko MK, Kay EP
Molecular vision 2002 Jan 11;8:1-9
Molecular vision 2002 Jan 11;8:1-9
Nitric oxide-induced apoptosis in RAW 264.7 macrophages is mediated by endoplasmic reticulum stress pathway involving ATF6 and CHOP.
Gotoh T, Oyadomari S, Mori K, Mori M
The Journal of biological chemistry 2002 Apr 5;277(14):12343-50
The Journal of biological chemistry 2002 Apr 5;277(14):12343-50
Truncation releases olfactory receptors from the endoplasmic reticulum of heterologous cells.
Gimelbrant AA, Stoss TD, Landers TM, McClintock TS
Journal of neurochemistry 1999 Jun;72(6):2301-11
Journal of neurochemistry 1999 Jun;72(6):2301-11
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Supportive validation
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- Enzo Life Sciences (provider)
- Main image
- Experimental details
- Western blot analysis: Lane 1: MW marker, Lane 2: 150 ng of Grp78 (BiP) recombinant protein (Prod. No. ADI-SPP-765), Lane 3: 20µg of CHO-K1 cell lysate, Lane 4: 20µg of mouse liver microsome tissue extract (Prod. No. ADI-LYT-MM100).
