GTX101448

Ono K, Eguchi T, Sogawa C, Calderwood SK, Futagawa J, Kasai T, Seno M, Okamoto K, Sasaki A, Kozaki KI
Journal of cellular biochemistry 2018 Sep;119(9):7350-7362

Anti-EGFR antibody cetuximab is secreted by oral squamous cell carcinoma and alters EGF-driven mesenchymal transition.

Fujiwara T, Eguchi T, Sogawa C, Ono K, Murakami J, Ibaragi S, Asaumi JI, Okamoto K, Calderwood SK, Kozaki KI
Biochemical and biophysical research communications 2018 Sep 10;503(3):1267-1272

Genomic analysis of DNA repair genes and androgen signaling in prostate cancer.

Jividen K, Kedzierska KZ, Yang CS, Szlachta K, Ratan A, Paschal BM
BMC cancer 2018 Oct 10;18(1):960

Carcinogenic epithelial-mesenchymal transition initiated by oral cancer exosomes is inhibited by anti-EGFR antibody cetuximab.

Fujiwara T, Eguchi T, Sogawa C, Ono K, Murakami J, Ibaragi S, Asaumi JI, Calderwood SK, Okamoto K, Kozaki KI
Oral oncology 2018 Nov;86:251-257

Anti-cancer activity of withaferin A in B-cell lymphoma.

McKenna MK, Gachuki BW, Alhakeem SS, Oben KN, Rangnekar VM, Gupta RC, Bondada S
Cancer biology & therapy 2015;16(7):1088-98

The unfolded protein response is shaped by the NMD pathway.

Karam R, Lou CH, Kroeger H, Huang L, Lin JH, Wilkinson MF
EMBO reports 2015 May;16(5):599-609

N-terminal functional domain of Gasdermin A3 regulates mitochondrial homeostasis via mitochondrial targeting.

Lin PH, Lin HY, Kuo CC, Yang LT
Journal of biomedical science 2015 Jun 24;22:44

Mutations in the unfolded protein response regulator ATF6 cause the cone dysfunction disorder achromatopsia.

Kohl S, Zobor D, Chiang WC, Weisschuh N, Staller J, Gonzalez Menendez I, Chang S, Beck SC, Garcia Garrido M, Sothilingam V, Seeliger MW, Stanzial F, Benedicenti F, Inzana F, Héon E, Vincent A, Beis J, Strom TM, Rudolph G, Roosing S, Hollander AI, Cremers FP, Lopez I, Ren H, Moore AT, Webster AR, Michaelides M, Koenekoop RK, Zrenner E, Kaufman RJ, Tsang SH, Wissinger B, Lin JH
Nature genetics 2015 Jul;47(7):757-65

No comments: Submit comment

Supportive validation

Submitted by: GeneTex (provider)
Main image
Experimental details: Sample(30 ?g of whole cell lysate)A:293TB:A431(GTX27909)7.5% SDS PAGEGTX101448 diluted at 1:1500The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.

Supportive validation

Submitted by: GeneTex (provider)
Main image
Experimental details: Various whole cell extracts (30 ?g) were separated by 7.5% SDS-PAGE, and the membrane was blotted with HSP90 beta antibody (GTX101448) diluted at 1:1500. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.

Supportive validation

Submitted by: GeneTex (provider)
Main image
Experimental details: Various whole cell extracts (30 ?g) were separated by 7.5% SDS-PAGE, and the membrane was blotted with HSP90 beta antibody (GTX101448) diluted at 1:1500. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.

Supportive validation

Submitted by: GeneTex (provider)
Main image
Experimental details: Immunofluorescence analysis of methanol-fixed HCT116, using HSP90 beta(GTX101448) antibody at 1:500 dilution.

Supportive validation

Submitted by: GeneTex (provider)
Main image
Experimental details: Immunohistochemical analysis of paraffin-embedded BT483 xenograft, using HSP90 beta(GTX101448) antibody at 1:100 dilution.

Supportive validation

Submitted by: GeneTex (provider)
Main image
Experimental details: HSP90 beta antibody detects HSP90 beta protein at cytosol on mouse skin by immunohistochemical analysis. Sample: Paraffin-embedded mouse skin. HSP90 beta antibody (GTX101448) dilution: 1:500.

Supportive validation

Submitted by: GeneTex (provider)
Main image
Experimental details: HSP90 beta antibody detects HSP90 beta protein at cytosol on mouse lung by immunohistochemical analysis. Sample: Paraffin-embedded mouse lung. HSP90 beta antibody (GTX101448) dilution: 1:500.