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- Antibody Data
- Antigen structure
- References [5]
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- Validations
- Western blot [1]
- Immunohistochemistry [2]
- Flow cytometry [1]
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- Product number
- 21738-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#21738-1-AP, RRID:AB_10733888
- Product name
- Integrin Beta 4 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated Integrin Beta 4 antibody (Cat. #21738-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: FC, IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references FAM83A exerts tumor‑suppressive roles in cervical cancer by regulating integrins.
Reciprocal regulation of integrin β4 and KLF4 promotes gliomagenesis through maintaining cancer stem cell traits.
17-allylamino-17-demethoxygeldanamycin impeded chemotherapy through antioxidant activation via reducing reactive oxygen species-induced cell death.
Programmed death ligand 1 promotes lymph node metastasis and glucose metabolism in cervical cancer by activating integrin β4/SNAI1/SIRT3 signaling pathway.
Integrin β4 promotes cell invasion and epithelial-mesenchymal transition through the modulation of Slug expression in hepatocellular carcinoma.
Xu J, Lu W
International journal of oncology 2020 Aug;57(2):509-521
International journal of oncology 2020 Aug;57(2):509-521
Reciprocal regulation of integrin β4 and KLF4 promotes gliomagenesis through maintaining cancer stem cell traits.
Ma B, Zhang L, Zou Y, He R, Wu Q, Han C, Zhang B
Journal of experimental & clinical cancer research : CR 2019 Jan 18;38(1):23
Journal of experimental & clinical cancer research : CR 2019 Jan 18;38(1):23
17-allylamino-17-demethoxygeldanamycin impeded chemotherapy through antioxidant activation via reducing reactive oxygen species-induced cell death.
Li Y, Chen Y, Qiu C, Ma X, Lei K, Cai G, Liang X, Liu J
Journal of cellular biochemistry 2018 Oct 30;
Journal of cellular biochemistry 2018 Oct 30;
Programmed death ligand 1 promotes lymph node metastasis and glucose metabolism in cervical cancer by activating integrin β4/SNAI1/SIRT3 signaling pathway.
Wang S, Li J, Xie J, Liu F, Duan Y, Wu Y, Huang S, He X, Wang Z, Wu X
Oncogene 2018 Jul;37(30):4164-4180
Oncogene 2018 Jul;37(30):4164-4180
Integrin β4 promotes cell invasion and epithelial-mesenchymal transition through the modulation of Slug expression in hepatocellular carcinoma.
Li XL, Liu L, Li DD, He YP, Guo LH, Sun LP, Liu LN, Xu HX, Zhang XP
Scientific reports 2017 Jan 13;7:40464
Scientific reports 2017 Jan 13;7:40464
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- MCF7 cells were subjected to SDS PAGE followed by western blot with 21738-1-AP(ITGB4 antibody) at dilution of 1:500
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human pancreas cancer using 21738-1-AP(ITGB4 antibody) at dilution of 1:100 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human pancreas cancer using 21738-1-AP(ITGB4 antibody) at dilution of 1:100 (under 40x lens)
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The Integrin beta-4 antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human Integrin beta-4. This antibody recognizes human,mouse,rat antigen. The Integrin beta-4 antibody has been validated for the following applications: ELISA, WB, IHC, FC analysis.
