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Western blotAntibody data
- Antibody Data
- Antigen structure
- References [3]
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- Validations
- Western blot [1]
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- Product number
- PAB7915 - Provider product page
- Provider
- Abnova Corporation
- Proper citation
- Abnova Corporation Cat#PAB7915, RRID:AB_1706937
- Product name
- ITGB4 (phospho Y1494) polyclonal antibody
- Antibody type
- Polyclonal
- Description
- Rabbit polyclonal antibody raised against synthetic phosphopeptide of ITGB4.
- Storage
- Store at -20°C.Aliquot to avoid repeated freezing and thawing.
Submitted references Curcumin inhibition of integrin (alpha6beta4)-dependent breast cancer cell motility and invasion.
Tyrosine phosphorylation of the beta 4 integrin cytoplasmic domain mediates Shc signaling to extracellular signal-regulated kinase and antagonizes formation of hemidesmosomes.
Identification of insulin receptor substrate 1 (IRS-1) and IRS-2 as signaling intermediates in the alpha6beta4 integrin-dependent activation of phosphoinositide 3-OH kinase and promotion of invasion.
Kim HI, Huang H, Cheepala S, Huang S, Chung J
Cancer prevention research (Philadelphia, Pa.) 2008 Oct;1(5):385-91
Cancer prevention research (Philadelphia, Pa.) 2008 Oct;1(5):385-91
Tyrosine phosphorylation of the beta 4 integrin cytoplasmic domain mediates Shc signaling to extracellular signal-regulated kinase and antagonizes formation of hemidesmosomes.
Dans M, Gagnoux-Palacios L, Blaikie P, Klein S, Mariotti A, Giancotti FG
The Journal of biological chemistry 2001 Jan 12;276(2):1494-502
The Journal of biological chemistry 2001 Jan 12;276(2):1494-502
Identification of insulin receptor substrate 1 (IRS-1) and IRS-2 as signaling intermediates in the alpha6beta4 integrin-dependent activation of phosphoinositide 3-OH kinase and promotion of invasion.
Shaw LM
Molecular and cellular biology 2001 Aug;21(15):5082-93
Molecular and cellular biology 2001 Aug;21(15):5082-93
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- Abnova Corporation (provider)
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- Experimental details
- Western blot analysis of A-431 cells serum starved overnight (lane 1) and treated with pervanadate (1mM) for 30 min (lane 2). The blots were probed with ITGB4 (phospho Y1494) polyclonal antibody (Cat # PAB7915).
