Antibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations
- Western blot [1]
- Immunocytochemistry [1]
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Validation data
Reference
Comment
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- Product number
- PAB12949 - Provider product page
- Provider
- Abnova Corporation
- Proper citation
- Abnova Corporation Cat#PAB12949, RRID:AB_10553953
- Product name
- IRS1 polyclonal antibody
- Antibody type
- Polyclonal
- Description
- Rabbit polyclonal antibody raised against synthetic peptide of IRS1.
- Storage
- Store at 4°C for three months. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.
Submitted references Integration of growth factor and nutrient signaling: implications for cancer biology.
A phosphatidylinositol 3-kinase/Akt/mTOR pathway mediates and PTEN antagonizes tumor necrosis factor inhibition of insulin signaling through insulin receptor substrate-1.
Insulin receptor substrate (IRS) transduction system: distinct and overlapping signaling potential.
Shamji AF, Nghiem P, Schreiber SL
Molecular cell 2003 Aug;12(2):271-80
Molecular cell 2003 Aug;12(2):271-80
A phosphatidylinositol 3-kinase/Akt/mTOR pathway mediates and PTEN antagonizes tumor necrosis factor inhibition of insulin signaling through insulin receptor substrate-1.
Ozes ON, Akca H, Mayo LD, Gustin JA, Maehama T, Dixon JE, Donner DB
Proceedings of the National Academy of Sciences of the United States of America 2001 Apr 10;98(8):4640-5
Proceedings of the National Academy of Sciences of the United States of America 2001 Apr 10;98(8):4640-5
Insulin receptor substrate (IRS) transduction system: distinct and overlapping signaling potential.
Giovannone B, Scaldaferri ML, Federici M, Porzio O, Lauro D, Fusco A, Sbraccia P, Borboni P, Lauro R, Sesti G
Diabetes/metabolism research and reviews 2000 Nov-Dec;16(6):434-41
Diabetes/metabolism research and reviews 2000 Nov-Dec;16(6):434-41
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Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Western blot analysis of IRS1 in PC-3 cell lysate with IRS1 polyclonal antibody (Cat # PAB12949) at (A) 1, (B) 2 and (C) 4 ug/mL .
Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Immunocytochemistry of IRS1 in P815 cells with IRS1 polyclonal antibody (Cat # PAB12949) at 2 ug/mL .
- Validation comment
- Immunocytochemistry